## Sun Mar 16 00:18:48 2025 ## emapper-2.1.9 ## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD1_bin.10.fa -m mmseqs --itype genome -o DYD1_bin.10 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD1_bin.10 --cpu 8 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs DYD1_k127_1045164_12 313612.L8106_08601 0.0001112 51.0 COG1988@1|root,COG1988@2|Bacteria,1G87P@1117|Cyanobacteria,1HG31@1150|Oscillatoriales 1117|Cyanobacteria S membrane-bound metal-dependent - - - ko:K07038 - - - - ko00000 - - - YdjM DYD1_k127_1045164_5 489825.LYNGBM3L_22490 3.979e-120 406.0 COG0578@1|root,COG0578@2|Bacteria,1G1T3@1117|Cyanobacteria,1H86N@1150|Oscillatoriales 1117|Cyanobacteria C FAD dependent oxidoreductase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C DYD1_k127_1045164_11 1121403.AUCV01000022_gene3504 6.738e-29 126.0 COG2227@1|root,COG2227@2|Bacteria,1R11D@1224|Proteobacteria,42RT6@68525|delta/epsilon subdivisions,2WNH2@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Nodulation protein S (NodS) - - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 DYD1_k127_1045164_0 1499967.BAYZ01000026_gene1631 1.963e-217 696.0 COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria 2|Bacteria E PFAM asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 DYD1_k127_1045164_9 1499967.BAYZ01000195_gene3102 6.751e-77 279.0 COG0438@1|root,COG0438@2|Bacteria,2NQRB@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_1045164_7 926569.ANT_15770 5.919e-100 344.0 COG0279@1|root,COG2203@1|root,COG0279@2|Bacteria,COG2203@2|Bacteria,2G6QD@200795|Chloroflexi 200795|Chloroflexi G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 DYD1_k127_1045164_2 926569.ANT_19990 3.371e-140 456.0 COG2605@1|root,COG2605@2|Bacteria,2G5TF@200795|Chloroflexi 200795|Chloroflexi S PFAM GHMP kinase - - 2.7.1.168 ko:K07031 ko00540,map00540 - R09770 RC00002,RC00078 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD1_k127_1045164_4 926569.ANT_15830 2.563e-128 422.0 COG1087@1|root,COG1087@2|Bacteria,2GA96@200795|Chloroflexi 200795|Chloroflexi M 3-beta hydroxysteroid dehydrogenase/isomerase family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd DYD1_k127_1045164_3 383372.Rcas_3974 1.093e-136 451.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G67F@200795|Chloroflexi,3769D@32061|Chloroflexia 32061|Chloroflexia M PFAM sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 DYD1_k127_1045164_8 926550.CLDAP_27900 7.346e-99 337.0 COG0438@1|root,COG0438@2|Bacteria,2G60E@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 DYD1_k127_1045164_6 926569.ANT_20340 5.984e-116 390.0 COG1215@1|root,COG1215@2|Bacteria,2G8HN@200795|Chloroflexi 200795|Chloroflexi M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3 DYD1_k127_1045164_10 926569.ANT_20320 2.01e-72 269.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glycos_transf_2 DYD1_k127_1045164_1 1385935.N836_31870 2.303e-151 487.0 COG1960@1|root,COG1960@2|Bacteria,1G4K8@1117|Cyanobacteria,1HE4R@1150|Oscillatoriales 1117|Cyanobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_107602_0 511051.CSE_14630 5.739e-219 687.0 COG0334@1|root,COG0334@2|Bacteria 2|Bacteria E glutamate dehydrogenase [NAD(P)+] activity gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009986,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793 ELFV_dehydrog,ELFV_dehydrog_N DYD1_k127_107602_1 926569.ANT_27120 4.543e-216 696.0 COG0574@1|root,COG0574@2|Bacteria 2|Bacteria G Belongs to the PEP-utilizing enzyme family - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PPDK_N DYD1_k127_1162197_6 926569.ANT_22470 2.425e-72 250.0 COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi 200795|Chloroflexi H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE,ThiS DYD1_k127_1162197_11 926569.ANT_22480 8.251e-53 190.0 COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC DYD1_k127_1162197_15 926569.ANT_16980 2.189e-17 83.0 COG0333@1|root,COG0333@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p DYD1_k127_1162197_4 1042163.BRLA_c033440 3.09e-77 271.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,26QJX@186822|Paenibacillaceae 91061|Bacilli I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 DYD1_k127_1162197_8 926569.ANT_12930 5.469e-66 238.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_1162197_3 671143.DAMO_1521 2.092e-88 302.0 COG0569@1|root,COG0569@2|Bacteria,2NPN3@2323|unclassified Bacteria 2|Bacteria P TrkA-C domain trkA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD1_k127_1162197_5 671143.DAMO_1520 3.983e-75 259.0 COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria 2|Bacteria P TrkA-N domain ceoB - - ko:K03499,ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD1_k127_1162197_0 671143.DAMO_0407 3.372e-299 929.0 COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria 2|Bacteria E Amino acid permease ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 DYD1_k127_1162197_14 316274.Haur_4061 4.938e-22 112.0 COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia 32061|Chloroflexia T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA DYD1_k127_1162197_7 926569.ANT_08930 2.636e-66 239.0 COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - - - - - - - - - - LytR_C,LytR_cpsA_psr DYD1_k127_1162197_13 926569.ANT_08930 1.615e-35 156.0 COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - - - - - - - - - - LytR_C,LytR_cpsA_psr DYD1_k127_1162197_2 926569.ANT_08920 3.311e-100 336.0 COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi 200795|Chloroflexi L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_1162197_12 1382304.JNIL01000001_gene2859 5.536e-48 179.0 COG1392@1|root,COG1392@2|Bacteria 2|Bacteria P Protein of unknown function DUF47 - - - ko:K07220 - - - - ko00000 - - - PhoU_div DYD1_k127_1162197_10 479434.Sthe_3397 1.251e-62 233.0 COG3839@1|root,COG3839@2|Bacteria 2|Bacteria P tungstate ion transport tupC - 3.6.3.55 ko:K06857 ko02010,map02010 M00186 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.2,3.A.1.6.4 - - ABC_tran DYD1_k127_1162197_9 479434.Sthe_3396 5.477e-64 228.0 COG4662@1|root,COG4662@2|Bacteria,2G6ZF@200795|Chloroflexi,27Z7U@189775|Thermomicrobia 189775|Thermomicrobia H Binding-protein-dependent transport system inner membrane component - - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 DYD1_k127_1162197_1 479434.Sthe_3395 1.721e-105 349.0 COG2998@1|root,COG2998@2|Bacteria,2G7MD@200795|Chloroflexi,27Z56@189775|Thermomicrobia 189775|Thermomicrobia H PBP superfamily domain - - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 DYD1_k127_1162197_16 326427.Cagg_2634 3.453e-11 64.0 COG4454@1|root,COG4454@2|Bacteria 2|Bacteria - - - GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 ko:K00368,ko:K18683 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cupredoxin_1,SoxE DYD1_k127_1176133_0 316274.Haur_4519 2.926e-15 81.0 COG1073@1|root,COG4842@1|root,COG1073@2|Bacteria,COG4842@2|Bacteria 2|Bacteria S protein secretion by the type VII secretion system - - 3.1.1.101 ko:K21104 - - R11540 - ko00000,ko01000 - - - Abhydrolase_5,Peptidase_C2,WXG100 DYD1_k127_1176133_4 293227.XP_008712801.1 6.813e-05 56.0 COG1716@1|root,KOG3872@2759|Eukaryota,39CGM@33154|Opisthokonta,3NYIV@4751|Fungi,3QMRH@4890|Ascomycota,20E53@147545|Eurotiomycetes,3MSE3@451870|Chaetothyriomycetidae 4751|Fungi O Forkhead associated domain - GO:0000075,GO:0000132,GO:0000226,GO:0000278,GO:0000281,GO:0000399,GO:0000910,GO:0000921,GO:0001100,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005815,GO:0005816,GO:0005856,GO:0005933,GO:0005934,GO:0005935,GO:0005938,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007088,GO:0007093,GO:0007094,GO:0007096,GO:0007105,GO:0007163,GO:0007346,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009966,GO:0009968,GO:0009987,GO:0010564,GO:0010639,GO:0010646,GO:0010648,GO:0010948,GO:0010965,GO:0010974,GO:0015630,GO:0016043,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0022402,GO:0022607,GO:0023051,GO:0023057,GO:0030010,GO:0030071,GO:0030427,GO:0031029,GO:0031030,GO:0031106,GO:0031577,GO:0031578,GO:0031991,GO:0032153,GO:0032155,GO:0032156,GO:0032161,GO:0032176,GO:0032177,GO:0032185,GO:0032186,GO:0032231,GO:0032446,GO:0032465,GO:0032466,GO:0032506,GO:0032879,GO:0032880,GO:0032954,GO:0032955,GO:0032956,GO:0032970,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0034613,GO:0034622,GO:0036211,GO:0040001,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044732,GO:0044810,GO:0045786,GO:0045839,GO:0045841,GO:0045930,GO:0046578,GO:0046580,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0051056,GO:0051058,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051293,GO:0051294,GO:0051301,GO:0051302,GO:0051493,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051726,GO:0051782,GO:0051783,GO:0051784,GO:0051865,GO:0051983,GO:0051985,GO:0060341,GO:0061630,GO:0061640,GO:0061659,GO:0065003,GO:0065007,GO:0070647,GO:0070727,GO:0070925,GO:0071173,GO:0071174,GO:0071704,GO:0071840,GO:0071944,GO:0090337,GO:0097271,GO:0099568,GO:0110020,GO:0110053,GO:0140096,GO:1901564,GO:1901891,GO:1901892,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902099,GO:1902100,GO:1902363,GO:1902364,GO:1902412,GO:1902413,GO:1902531,GO:1902532,GO:1902850,GO:1902903,GO:1903047,GO:1903436,GO:1903437,GO:1903827,GO:1903828,GO:1905818,GO:1905819,GO:2000816,GO:2001251 - ko:K08994 - - - - ko00000,ko02000 1.A.46.2 - - FHA,zf-RING_11 DYD1_k127_1176133_1 768671.ThimaDRAFT_4782 4.66e-12 79.0 COG2304@1|root,COG2304@2|Bacteria,1PBVT@1224|Proteobacteria,1S8TI@1236|Gammaproteobacteria,1WZBX@135613|Chromatiales 135613|Chromatiales S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA_2 DYD1_k127_1176133_3 749927.AMED_3662 5.652e-05 54.0 COG3164@1|root,COG3250@1|root,COG3164@2|Bacteria,COG3250@2|Bacteria,2I3EF@201174|Actinobacteria 201174|Actinobacteria G alpha-L-rhamnosidase - - - - - - - - - - - - Glyco_hydro_106 DYD1_k127_1183126_0 926569.ANT_10860 0.0 1924.0 COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi 200795|Chloroflexi K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 DYD1_k127_1183126_2 926569.ANT_10850 2.12e-167 567.0 COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity phoR GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K02484,ko:K07636,ko:K07642 ko02020,map02020 M00434,M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 DYD1_k127_1183126_3 926569.ANT_12920 8.74e-93 318.0 COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi 200795|Chloroflexi KT AAA domain - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - Response_reg DYD1_k127_1183126_5 1144275.COCOR_06733 8.663e-45 179.0 COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1MXH7@1224|Proteobacteria,43AYG@68525|delta/epsilon subdivisions 1224|Proteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_1183126_1 926569.ANT_12970 5.873e-181 587.0 COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi 200795|Chloroflexi L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C DYD1_k127_1183126_4 926569.ANT_12960 6.138e-52 191.0 COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - ko:K07025 - - - - ko00000 - - - HAD_2 DYD1_k127_1190808_3 1038859.AXAU01000004_gene4526 5.681e-35 142.0 COG4249@1|root,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria,3JQPH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caspase domain - - - - - - - - - - - - Peptidase_C14 DYD1_k127_1190808_2 1297569.MESS2_1220011 2.457e-39 156.0 COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria,2UC92@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Rhodopirellula transposase DDE domain - - - - - - - - - - - - DDE_Tnp_ISAZ013 DYD1_k127_1190808_0 525904.Tter_0079 8.774e-117 389.0 COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria 2|Bacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 ko:K01919,ko:K03072,ko:K12257 ko00270,ko00480,ko01100,ko02024,ko03060,ko03070,map00270,map00480,map01100,map02024,map03060,map03070 M00118,M00335 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - GshA,SecD_SecF,Sec_GG DYD1_k127_1190808_5 926569.ANT_16750 4.898e-26 111.0 COG0125@1|root,COG0125@2|Bacteria,2GBP3@200795|Chloroflexi 200795|Chloroflexi F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - - - - - - - - - - - DYD1_k127_1190808_1 926569.ANT_16730 1.026e-67 240.0 COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi 200795|Chloroflexi KT PFAM Stage II sporulation E family protein - - - - - - - - - - - - SpoIIE DYD1_k127_1190808_4 370438.PTH_1597 8.61e-34 146.0 COG0642@1|root,COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,264H3@186807|Peptococcaceae 186801|Clostridia T Signal transduction histidine kinase - - - - - - - - - - - - Fe_hyd_lg_C,HATPase_c,HisKA,Response_reg DYD1_k127_1211068_59 1125863.JAFN01000001_gene2793 1.987e-18 95.0 COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Cytochrome c pcmF - - - - - - - - - - - Cytochrom_C DYD1_k127_1211068_53 926569.ANT_26960 5.073e-31 135.0 2EH75@1|root,33AYZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1211068_39 926550.CLDAP_25550 1.5e-49 195.0 COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,2G8PE@200795|Chloroflexi 200795|Chloroflexi T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 DYD1_k127_1211068_31 1382306.JNIM01000001_gene1045 2.863e-62 220.0 COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi 200795|Chloroflexi K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg DYD1_k127_1211068_2 926569.ANT_21930 3.019e-250 791.0 COG5492@1|root,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - 3.2.1.81,3.2.1.97 ko:K01219,ko:K17624 - - - - ko00000,ko01000 - GH101 - Big_2,CBM_6,Cytochrome_C7,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,WxL DYD1_k127_1211068_40 525904.Tter_2548 1.943e-47 178.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,HATPase_c,HisKA_3,Response_reg DYD1_k127_1211068_46 479434.Sthe_0156 5.32e-39 164.0 COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia 189775|Thermomicrobia T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA_3 DYD1_k127_1211068_66 479434.Sthe_2107 1.061e-09 72.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3,PSCyt1 DYD1_k127_1211068_61 760192.Halhy_4417 5.485e-15 89.0 COG0607@1|root,COG2010@1|root,COG3185@1|root,COG0607@2|Bacteria,COG2010@2|Bacteria,COG3185@2|Bacteria 2|Bacteria E 4-Hydroxyphenylpyruvate dioxygenase - - 5.1.99.1 ko:K00406,ko:K05606,ko:K17315 ko00190,ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,ko02010,ko02020,map00190,map00280,map00630,map00640,map00720,map01100,map01120,map01200,map02010,map02020 M00156,M00373,M00375,M00376,M00605,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.24,3.A.1.1.30,3.D.4.3 - - Cytochrome_CBB3,Glyoxalase_3,Glyoxalase_4,Rhodanese DYD1_k127_1211068_56 1157490.EL26_05650 2.774e-27 130.0 COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1TRS8@1239|Firmicutes,4H9XH@91061|Bacilli,277YX@186823|Alicyclobacillaceae 91061|Bacilli C Cytochrome b(C-terminal)/b6/petD qcrC - - ko:K03888 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002 - - - Cytochrom_B_C,Cytochrome_CBB3 DYD1_k127_1211068_28 330214.NIDE3889 8.414e-74 254.0 COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae 2|Bacteria C Cytochrome b/b6/petB qcrC - - ko:K00412,ko:K03888 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3 DYD1_k127_1211068_55 234267.Acid_6209 2.215e-27 118.0 COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria 57723|Acidobacteria C Rieske [2Fe-2S] domain - - - ko:K03886 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske DYD1_k127_1211068_6 926569.ANT_21940 1.377e-191 613.0 COG3005@1|root,COG3005@2|Bacteria 2|Bacteria C denitrification pathway - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_NNT,Cytochrom_c3_2 DYD1_k127_1211068_16 926569.ANT_26970 1.282e-106 360.0 COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria 2|Bacteria C formate dehydrogenase - - - - - - - - - - - - Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1 DYD1_k127_1211068_15 926569.ANT_26980 7.553e-109 381.0 COG3005@1|root,COG3005@2|Bacteria 2|Bacteria C denitrification pathway - - - - - - - - - - - - Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1 DYD1_k127_1211068_42 926569.ANT_26970 4.114e-43 174.0 COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria 2|Bacteria C formate dehydrogenase - - - - - - - - - - - - Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1 DYD1_k127_1211068_25 290397.Adeh_2002 9.134e-81 284.0 COG3005@1|root,COG3005@2|Bacteria,1QYG3@1224|Proteobacteria,43CC8@68525|delta/epsilon subdivisions,2X7N4@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Cytochrome c3 - - - - - - - - - - - - Paired_CXXCH_1 DYD1_k127_1211068_32 1121413.JMKT01000008_gene1588 9.866e-60 231.0 COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42N47@68525|delta/epsilon subdivisions,2WIKZ@28221|Deltaproteobacteria,2M8JX@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM Polysulphide reductase, NrfD qrcD - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD DYD1_k127_1211068_33 1457250.BBMO01000001_gene477 4.231e-59 215.0 COG0437@1|root,arCOG01500@2157|Archaea,2XU83@28890|Euryarchaeota,23TXG@183963|Halobacteria 183963|Halobacteria C COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11,Fer4_4 DYD1_k127_1211068_65 1382359.JIAL01000001_gene327 6.219e-11 74.0 COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria,2JJ2B@204432|Acidobacteriia 204432|Acidobacteriia C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 DYD1_k127_1211068_29 864051.BurJ1DRAFT_3878 1.322e-71 257.0 COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria 1224|Proteobacteria S Ethylbenzene dehydrogenase - - - - - - - - - - - - EB_dh DYD1_k127_1211068_35 926569.ANT_19490 9.579e-58 205.0 COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi 200795|Chloroflexi O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH - - - ko:K02197 - - - - ko00000 - - - CcmE DYD1_k127_1211068_8 552811.Dehly_0435 2.763e-167 549.0 COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi 200795|Chloroflexi O PFAM Cytochrome C assembly protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD1_k127_1211068_45 926569.ANT_19460 3.75e-39 157.0 COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi 200795|Chloroflexi O subunit of a heme lyase ccmH - - ko:K02200 - - - - ko00000 - - - CcmH DYD1_k127_1211068_48 926550.CLDAP_40040 2.896e-37 147.0 COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi 200795|Chloroflexi CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,DnaJ DYD1_k127_1211068_62 926569.ANT_19430 4.71e-14 78.0 2DRD8@1|root,33BA3@2|Bacteria,2G7EV@200795|Chloroflexi 200795|Chloroflexi S zinc-ribbon domain - - - - - - - - - - - - zinc_ribbon_2 DYD1_k127_1211068_23 926569.ANT_19420 8.124e-88 316.0 COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi 200795|Chloroflexi C Cytochrome c - - - - - - - - - - - - CarboxypepD_reg,Cytochrome_CBB3 DYD1_k127_1211068_21 926569.ANT_19410 1.237e-90 306.0 COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran DYD1_k127_1211068_18 926569.ANT_19400 1.494e-96 321.0 COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi 200795|Chloroflexi O PFAM cytochrome c-type biogenesis protein CcmB ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB DYD1_k127_1211068_22 926569.ANT_19390 4.667e-89 300.0 COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi 200795|Chloroflexi O PFAM Cytochrome C assembly protein ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm DYD1_k127_1211068_50 903818.KI912268_gene670 4.808e-35 145.0 COG2324@1|root,COG2324@2|Bacteria,3Y7JJ@57723|Acidobacteria 57723|Acidobacteria S Carotenoid biosynthesis protein - - - - - - - - - - - - Caroten_synth DYD1_k127_1211068_54 298653.Franean1_2835 1.158e-27 128.0 COG3613@1|root,COG3613@2|Bacteria,2H4SW@201174|Actinobacteria 201174|Actinobacteria F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr DYD1_k127_1211068_47 1307761.L21SP2_3097 5.538e-38 159.0 COG1428@1|root,COG1428@2|Bacteria,2JAVV@203691|Spirochaetes 203691|Spirochaetes F Deoxynucleoside kinase dck - 2.7.1.74 ko:K00893 ko00230,ko00240,ko01100,map00230,map00240,map01100 - R00185,R01666 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK DYD1_k127_1211068_41 797299.HALLA_03760 1.979e-43 170.0 COG0697@1|root,arCOG00271@2157|Archaea,2XY2J@28890|Euryarchaeota,23Z1Z@183963|Halobacteria 183963|Halobacteria G EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_1211068_51 1089553.Tph_c26660 3.087e-34 135.0 COG2365@1|root,COG2365@2|Bacteria 2|Bacteria T protein tyrosine phosphatase activity iphP - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 DYD1_k127_1211068_19 926569.ANT_30970 6.11e-96 317.0 COG1838@1|root,COG1838@2|Bacteria,2G74D@200795|Chloroflexi 200795|Chloroflexi C Fumarase C-terminus - - 4.2.1.2 ko:K01676,ko:K01678 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase_C DYD1_k127_1211068_14 926569.ANT_30960 2.065e-121 397.0 COG1951@1|root,COG1951@2|Bacteria,2G6YI@200795|Chloroflexi 200795|Chloroflexi C Fumarate hydratase (Fumerase) - - 4.2.1.2 ko:K01676,ko:K01677 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase DYD1_k127_1211068_5 518766.Rmar_1549 4.642e-235 745.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FIUV@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C dehydrogenase, E1 component bfmBAB - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C DYD1_k127_1211068_10 926569.ANT_30000 1.478e-152 494.0 COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi 200795|Chloroflexi L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_III,MutS_V,Smr DYD1_k127_1211068_26 926569.ANT_30000 3.08e-80 278.0 COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi 200795|Chloroflexi L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_III,MutS_V,Smr DYD1_k127_1211068_64 1321778.HMPREF1982_02132 2.535e-11 74.0 2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_1211068_30 1232410.KI421428_gene1027 8.316e-63 222.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,43SFH@69541|Desulfuromonadales 28221|Deltaproteobacteria L Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco DYD1_k127_1211068_63 880074.BARVI_11285 1.824e-12 73.0 COG0375@1|root,COG0375@2|Bacteria,4NWR5@976|Bacteroidetes,2FV7V@200643|Bacteroidia,22YT9@171551|Porphyromonadaceae 976|Bacteroidetes S Probably plays a role in a hydrogenase nickel cofactor insertion step hypA - - ko:K04651 - - - - ko00000,ko03110 - - - HypA DYD1_k127_1211068_27 926569.ANT_17850 3.034e-75 260.0 COG0378@1|root,COG0378@2|Bacteria,2G6EP@200795|Chloroflexi 200795|Chloroflexi KO Hydrogenase accessory protein HypB hypB - - ko:K03189,ko:K04652 - - - - ko00000,ko03110 - - - cobW DYD1_k127_1211068_4 926569.ANT_17860 1.941e-235 752.0 COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi 200795|Chloroflexi O Belongs to the carbamoyltransferase HypF family hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF DYD1_k127_1211068_58 926569.ANT_17870 6.866e-20 98.0 COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi 200795|Chloroflexi O PFAM hydrogenase expression formation protein (HUPF HYPC) hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC DYD1_k127_1211068_9 357808.RoseRS_0974 7.684e-164 525.0 COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,376PX@32061|Chloroflexia 32061|Chloroflexia O TIGRFAM hydrogenase expression formation protein HypD - - - ko:K04654 - - - - ko00000 - - - HypD DYD1_k127_1211068_13 1000565.METUNv1_03210 7.236e-127 416.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,2KVH9@206389|Rhodocyclales 206389|Rhodocyclales O hydrogenase expression formation protein HypE hypE - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C DYD1_k127_1211068_37 1168034.FH5T_19015 3.032e-56 213.0 COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes 976|Bacteroidetes C oxidoreductase - - - - - - - - - - - - - DYD1_k127_1211068_20 237368.SCABRO_02910 6.484e-91 314.0 COG0644@1|root,COG0644@2|Bacteria,2J1WS@203682|Planctomycetes 203682|Planctomycetes C oxidoreductase - - - - - - - - - - - - - DYD1_k127_1211068_24 322710.Avin_04470 2.536e-82 287.0 COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,1SGMS@1236|Gammaproteobacteria 1236|Gammaproteobacteria D CobQ/CobB/MinD/ParA nucleotide binding domain - - - ko:K07321 - - - - ko00000 - - - CbiA DYD1_k127_1211068_11 1125863.JAFN01000001_gene1547 6.845e-141 462.0 COG1150@1|root,COG2048@1|root,COG1150@2|Bacteria,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria 28221|Deltaproteobacteria C heterodisulfide reductase hdrB - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG DYD1_k127_1211068_12 1125863.JAFN01000001_gene1548 1.345e-133 436.0 COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM Methylenetetrahydrofolate reductase - - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - CdhD,MTHFR DYD1_k127_1211068_17 1125863.JAFN01000001_gene1549 5.247e-97 325.0 COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria 28221|Deltaproteobacteria C PFAM Methylene-tetrahydrofolate reductase C terminal - - - - - - - - - - - - MTHFR_C DYD1_k127_1211068_38 429009.Adeg_0343 1.278e-52 190.0 COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales 186801|Clostridia C Methyl-viologen-reducing hydrogenase, delta subunit - - - - - - - - - - - - FlpD DYD1_k127_1211068_1 1125863.JAFN01000001_gene1552 0.0 1594.0 COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria 2|Bacteria C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2 DYD1_k127_1211068_49 426117.M446_3558 2.779e-36 147.0 COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,2TXMN@28211|Alphaproteobacteria,1JQWM@119045|Methylobacteriaceae 28211|Alphaproteobacteria T SMART PAS domain containing protein - - - - - - - - - - - - CHASE3,HATPase_c,HisKA,PAS_4,Response_reg DYD1_k127_1211068_52 187272.Mlg_1802 8.744e-32 140.0 COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SYV3@1236|Gammaproteobacteria,1X16X@135613|Chromatiales 135613|Chromatiales T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA DYD1_k127_1211068_60 1121468.AUBR01000040_gene1730 9.011e-18 85.0 COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales 186801|Clostridia C Methyl-viologen-reducing hydrogenase, delta subunit - - - - - - - - - - - - FlpD DYD1_k127_1211068_57 264732.Moth_1193 9.53e-24 101.0 COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales 186801|Clostridia C Methyl-viologen-reducing hydrogenase, delta subunit - - - - - - - - - - - - FlpD DYD1_k127_1211068_0 1125863.JAFN01000001_gene1552 0.0 1825.0 COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria 2|Bacteria C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2 DYD1_k127_1211068_43 264732.Moth_1193 9.757e-42 162.0 COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales 186801|Clostridia C Methyl-viologen-reducing hydrogenase, delta subunit - - - - - - - - - - - - FlpD DYD1_k127_1211068_68 552811.Dehly_0517 3.61e-05 56.0 COG1148@1|root,COG1148@2|Bacteria,2G7GY@200795|Chloroflexi 200795|Chloroflexi C 4Fe-4S binding domain - - - - - - - - - - - - - DYD1_k127_1211068_3 760568.Desku_0188 2.531e-247 803.0 COG1148@1|root,COG1148@2|Bacteria 2|Bacteria C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388,ko:K16885,ko:K16886 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_20,Fer4_4,Fer4_7,FlpD,Pyr_redox_2 DYD1_k127_1211068_36 351160.RRC232 2.97e-56 208.0 COG0492@1|root,arCOG01297@2157|Archaea,2Y84N@28890|Euryarchaeota,2N9Q1@224756|Methanomicrobia 224756|Methanomicrobia O PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase trxB-1 - 1.8.1.9 ko:K00384,ko:K03387 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Glutaredoxin,Pyr_redox_2 DYD1_k127_1211068_7 1047013.AQSP01000073_gene1101 6.335e-191 606.0 COG0281@1|root,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria 2|Bacteria C Malic enzyme, NAD binding domain mez_1 - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic DYD1_k127_1211068_34 264732.Moth_1197 7.343e-59 215.0 COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,42JFY@68295|Thermoanaerobacterales 186801|Clostridia E Pterin binding enzyme acsE - 2.1.1.13,2.1.1.258 ko:K00548,ko:K15023 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230 M00017,M00377 R00946,R02289,R09365,R10243 RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind DYD1_k127_1216434_34 1123401.JHYQ01000003_gene2174 0.0003692 52.0 COG3650@1|root,COG3650@2|Bacteria,1R2PG@1224|Proteobacteria 1224|Proteobacteria S Bacterial SH3 domain homologues - - - - - - - - - - - - - DYD1_k127_1216434_0 357808.RoseRS_1605 7.136e-291 917.0 COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,374Z8@32061|Chloroflexia 32061|Chloroflexia O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD1_k127_1216434_3 926569.ANT_15320 5.412e-159 513.0 COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi 200795|Chloroflexi H PFAM cytoplasmic peptidoglycan synthetase domain protein folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M DYD1_k127_1216434_25 1201290.M902_2886 2.89e-41 166.0 COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,42VZ4@68525|delta/epsilon subdivisions,2MSSI@213481|Bdellovibrionales,2WRDI@28221|Deltaproteobacteria 213481|Bdellovibrionales P ABC transporter, phosphonate, periplasmic substrate-binding protein phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd DYD1_k127_1216434_7 1307761.L21SP2_1483 2.26e-100 335.0 COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes 203691|Spirochaetes P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran DYD1_k127_1216434_21 1131269.AQVV01000005_gene388 6.488e-55 214.0 COG3639@1|root,COG3639@2|Bacteria 2|Bacteria P organic phosphonate transmembrane transporter activity phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 DYD1_k127_1216434_17 926569.ANT_09940 1.011e-66 231.0 COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi 200795|Chloroflexi L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 DYD1_k127_1216434_24 292459.STH124 3.162e-44 175.0 COG1920@1|root,COG1920@2|Bacteria,1V86Y@1239|Firmicutes,24K51@186801|Clostridia 186801|Clostridia S GTP binding - - - - - - - - - - - - - DYD1_k127_1216434_20 926569.ANT_20690 6.465e-57 204.0 COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi 200795|Chloroflexi J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE DYD1_k127_1216434_28 290397.Adeh_0236 2.307e-35 143.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2YVCY@29|Myxococcales 28221|Deltaproteobacteria S Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran DYD1_k127_1216434_8 926569.ANT_20670 1.911e-99 334.0 COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi 200795|Chloroflexi NU PFAM type II secretion system protein - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF DYD1_k127_1216434_11 926569.ANT_20660 1.848e-94 319.0 COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi 200795|Chloroflexi U PFAM type II secretion system protein - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF DYD1_k127_1216434_1 926569.ANT_20650 1.691e-219 691.0 COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi 200795|Chloroflexi U PFAM type II secretion system protein E - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE DYD1_k127_1216434_6 926569.ANT_20640 2.273e-119 399.0 COG2201@1|root,COG4963@1|root,COG2201@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi 200795|Chloroflexi D PFAM response regulator receiver - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,CbiA,ParA,Response_reg DYD1_k127_1216434_18 926569.ANT_20630 4.057e-59 220.0 COG3745@1|root,COG3745@2|Bacteria 2|Bacteria U Flp pilus assembly protein CpaB cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF DYD1_k127_1216434_13 926569.ANT_11580 2.299e-91 321.0 COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi 200795|Chloroflexi T histidine kinase, dimerisation and phosphoacceptor region - - 2.7.13.3 ko:K07777 ko02020,map02020 M00478 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DegS,HATPase_c,HisKA_3 DYD1_k127_1216434_19 309801.trd_1669 1.504e-58 211.0 COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia 189775|Thermomicrobia K Two component transcriptional regulator, LuxR family - - - - - - - - - - - - GerE,Response_reg DYD1_k127_1216434_5 926569.ANT_11560 5.795e-126 424.0 COG1269@1|root,COG1269@2|Bacteria 2|Bacteria C ATP hydrolysis coupled proton transport - - - - - - - - - - - - PMT_2 DYD1_k127_1216434_9 926569.ANT_11540 2.669e-99 344.0 COG5305@1|root,COG5305@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PMT_2 DYD1_k127_1216434_23 926569.ANT_11570 3.318e-45 186.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT,PMT_2 DYD1_k127_1216434_14 926569.ANT_26880 3.877e-88 310.0 COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi 200795|Chloroflexi S oligosaccharyl transferase activity - - - - - - - - - - - - - DYD1_k127_1216434_10 926569.ANT_11500 2.918e-98 344.0 COG1807@1|root,COG1807@2|Bacteria,2G991@200795|Chloroflexi 200795|Chloroflexi M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - DYD1_k127_1216434_4 926569.ANT_11490 7.184e-130 442.0 COG1807@1|root,COG1807@2|Bacteria,2G9HX@200795|Chloroflexi 200795|Chloroflexi M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - DYD1_k127_1216434_29 1303518.CCALI_00022 7.612e-24 105.0 COG0863@1|root,COG2852@1|root,COG0863@2|Bacteria,COG2852@2|Bacteria 2|Bacteria L Protein conserved in bacteria - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - DUF559,N6_N4_Mtase DYD1_k127_1216434_2 926569.ANT_18690 6.246e-185 588.0 COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi 200795|Chloroflexi K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_1216434_33 321327.CYA_2879 4.306e-06 55.0 2DN50@1|root,32VJ4@2|Bacteria,1GND9@1117|Cyanobacteria,1H0SG@1129|Synechococcus 1117|Cyanobacteria S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 DYD1_k127_1216434_22 1340493.JNIF01000004_gene358 1.16e-48 194.0 28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - DYD1_k127_1216434_12 1210884.HG799464_gene10754 1.398e-91 309.0 COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes 203682|Planctomycetes NOU Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD1_k127_1216434_16 795666.MW7_0066 1.569e-78 269.0 COG1024@1|root,COG1024@2|Bacteria,1R446@1224|Proteobacteria,2VQJ4@28216|Betaproteobacteria,1KD32@119060|Burkholderiaceae 28216|Betaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD1_k127_1216434_30 1188256.BASI01000005_gene1825 1.708e-15 76.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TQJR@28211|Alphaproteobacteria,3FCRB@34008|Rhodovulum 28211|Alphaproteobacteria I Acetyl-coenzyme A synthetase N-terminus prpE - 6.2.1.1,6.2.1.17 ko:K01895,ko:K01908 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD1_k127_1217320_5 926569.ANT_12100 6.862e-107 365.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM,OapA,OapA_N,Peptidase_M23 DYD1_k127_1217320_1 1121468.AUBR01000038_gene1955 1.994e-168 539.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales 186801|Clostridia C PFAM Acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_1217320_6 479434.Sthe_2328 4.521e-89 308.0 COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi,27Z66@189775|Thermomicrobia 189775|Thermomicrobia V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_1217320_9 765420.OSCT_0965 7.949e-64 240.0 28M0D@1|root,2ZAFE@2|Bacteria,2G9HQ@200795|Chloroflexi 200795|Chloroflexi S Putative ATP-binding cassette - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran_2 DYD1_k127_1217320_3 909663.KI867150_gene72 9.361e-113 377.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MRD6@213462|Syntrophobacterales 28221|Deltaproteobacteria L helicase superfamily c-terminal domain rhlE-2 - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C DYD1_k127_1217320_10 1313172.YM304_08050 1.227e-40 169.0 2DFIR@1|root,2ZS07@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1217320_7 1128421.JAGA01000002_gene1691 7.992e-86 304.0 COG3694@1|root,COG3694@2|Bacteria,2NQKI@2323|unclassified Bacteria 2|Bacteria S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 DYD1_k127_1217320_8 1382306.JNIM01000001_gene1764 5.892e-82 284.0 COG4587@1|root,COG4587@2|Bacteria,2G9N0@200795|Chloroflexi 200795|Chloroflexi S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 DYD1_k127_1217320_2 1128421.JAGA01000002_gene1693 8.299e-136 442.0 COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria 2|Bacteria S AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_1217320_4 395961.Cyan7425_3419 2.98e-108 362.0 COG2006@1|root,COG2006@2|Bacteria,1G0X0@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF362) - - - - - - - - - - - - DUF362 DYD1_k127_1217320_14 194439.CT1729 1.649e-18 90.0 COG2189@1|root,COG2852@1|root,COG2189@2|Bacteria,COG2852@2|Bacteria,1FEW7@1090|Chlorobi 1090|Chlorobi L DNA methylase - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase DYD1_k127_1217320_0 1487953.JMKF01000028_gene1253 1.18e-187 629.0 COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H9JN@1150|Oscillatoriales 1117|Cyanobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,FHA,GAF,GGDEF,PAS_3,PAS_9,Response_reg DYD1_k127_1217320_11 1121946.AUAX01000019_gene7777 6.508e-38 153.0 COG3340@1|root,COG3340@2|Bacteria,2ISWE@201174|Actinobacteria 201174|Actinobacteria E Peptidase family S51 - - - - - - - - - - - - Peptidase_S51 DYD1_k127_1217320_13 570952.ATVH01000011_gene628 8.256e-19 102.0 2F4MK@1|root,33XB4@2|Bacteria,1NWZX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_1217320_15 570967.JMLV01000003_gene2233 9.582e-15 89.0 2F4MK@1|root,33XB4@2|Bacteria,1NWZX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_1217320_16 383372.Rcas_3422 9.872e-09 66.0 COG3266@1|root,COG3266@2|Bacteria 2|Bacteria GM domain, Protein - - - ko:K09766 - - - - ko00000 - - - YSIRK_signal DYD1_k127_1240790_0 1123242.JH636435_gene1594 1.782e-95 321.0 COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes 203682|Planctomycetes C B12 binding domain - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM DYD1_k127_1240790_1 585423.KR49_01530 4.717e-21 105.0 COG0204@1|root,COG0204@2|Bacteria,1G0U3@1117|Cyanobacteria,1GZVM@1129|Synechococcus 1117|Cyanobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase DYD1_k127_1272565_5 926569.ANT_19020 2.21e-14 74.0 COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi 200795|Chloroflexi J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD1_k127_1272565_1 926569.ANT_10010 0.0 1034.0 COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_1272565_3 479434.Sthe_1032 1.38e-55 198.0 COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi,27Y66@189775|Thermomicrobia 189775|Thermomicrobia J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 DYD1_k127_1272565_2 926569.ANT_09990 9.965e-66 229.0 COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi 200795|Chloroflexi J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 DYD1_k127_1272565_0 926569.ANT_09980 0.0 1493.0 COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi 200795|Chloroflexi K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 DYD1_k127_1272565_4 240016.ABIZ01000001_gene2009 6.374e-29 120.0 COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,2ITKY@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Cytochrome C and Quinol oxidase polypeptide I - - - - - - - - - - - - COX1 DYD1_k127_1273364_0 316274.Haur_1174 4.624e-66 239.0 COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi,375EF@32061|Chloroflexia 32061|Chloroflexia H PFAM sugar isomerase (SIS) - - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - SIS DYD1_k127_1273364_2 28444.JODQ01000006_gene106 1.644e-43 167.0 2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4EJ8Z@85012|Streptosporangiales 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_1273364_1 670487.Ocepr_1935 1.883e-52 196.0 COG0433@1|root,COG1196@1|root,COG0433@2|Bacteria,COG1196@2|Bacteria,1WM64@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus D nuclear chromosome segregation - - - - - - - - - - - - - DYD1_k127_1288825_0 926569.ANT_10380 2.397e-95 323.0 COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM MazG family protein - - - ko:K02499 - - - - ko00000,ko03036 - - - MazG,TP_methylase DYD1_k127_1288825_1 329726.AM1_4292 9.019e-62 216.0 COG0170@1|root,COG0170@2|Bacteria,1G9XA@1117|Cyanobacteria 1117|Cyanobacteria I dolichyl monophosphate biosynthetic process - - - - - - - - - - - - - DYD1_k127_1299925_1 266117.Rxyl_1153 4.513e-67 237.0 COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria 201174|Actinobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 DYD1_k127_1299925_3 1173024.KI912148_gene3458 5.762e-35 136.0 COG4274@1|root,COG4274@2|Bacteria 2|Bacteria S GYD domain - - - - - - - - - - - - GYD DYD1_k127_1299925_2 926550.CLDAP_14230 2.417e-62 220.0 COG1839@1|root,COG1839@2|Bacteria,2G6BH@200795|Chloroflexi 200795|Chloroflexi S Adenosine specific kinase - - - ko:K09129 - - - - ko00000 - - - Adenosine_kin DYD1_k127_1299925_5 103733.JNYO01000042_gene6051 2.285e-15 83.0 2AYAM@1|root,31QD5@2|Bacteria,2HSGB@201174|Actinobacteria,4EDMG@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_1299925_0 926569.ANT_18600 2.13e-122 401.0 COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi 200795|Chloroflexi EQ PFAM peptidase S58, DmpA - - - - - - - - - - - - Peptidase_S58 DYD1_k127_1299925_4 926569.ANT_08490 1.794e-34 148.0 COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi 200795|Chloroflexi M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin DYD1_k127_1310807_1 926569.ANT_09810 3.052e-140 454.0 COG2008@1|root,COG2008@2|Bacteria,2G5XG@200795|Chloroflexi 200795|Chloroflexi E aromatic amino acid beta-eliminating lyase threonine aldolase gly1 - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase DYD1_k127_1310807_3 926569.ANT_09800 1.04e-96 334.0 COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi 200795|Chloroflexi J Responsible for synthesis of pseudouridine from uracil - GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_1310807_7 926569.ANT_09790 1.036e-33 138.0 COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi 200795|Chloroflexi M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 DYD1_k127_1310807_0 525904.Tter_0977 0.0 1197.0 COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria 2|Bacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_0027,iPC815.YPO0475 Anticodon_1,tRNA-synt_1,zf-FPG_IleRS DYD1_k127_1310807_5 485913.Krac_8827 2.006e-86 293.0 COG2872@1|root,COG2872@2|Bacteria,2GA6P@200795|Chloroflexi 200795|Chloroflexi S Threonyl alanyl tRNA synthetase SAD - - - ko:K07050 - - - - ko00000,ko01000,ko03016 - - - tRNA-synt_2c,tRNA_SAD DYD1_k127_1310807_8 479434.Sthe_0458 3.479e-17 93.0 COG0328@1|root,COG0328@2|Bacteria,2GB0N@200795|Chloroflexi,27YNH@189775|Thermomicrobia 189775|Thermomicrobia L Reverse transcriptase-like - - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 DYD1_k127_1310807_6 926569.ANT_04320 2.761e-86 294.0 COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi 200795|Chloroflexi S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_1310807_4 926569.ANT_23030 7.152e-94 325.0 COG0739@1|root,COG0739@2|Bacteria 2|Bacteria M heme binding - - - - - - - - - - - - APH,Aminotran_3,Peptidase_M23 DYD1_k127_1310807_2 926569.ANT_23020 5.493e-116 397.0 COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi 200795|Chloroflexi U WD40 domain protein beta Propeller - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 DYD1_k127_1346215_2 1128421.JAGA01000002_gene1649 2.168e-121 395.0 COG0616@1|root,COG0616@2|Bacteria,2NQ3T@2323|unclassified Bacteria 2|Bacteria OU Serine dehydrogenase proteinase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,SDH_sah DYD1_k127_1346215_5 326427.Cagg_3526 3.218e-80 274.0 COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,375V4@32061|Chloroflexia 32061|Chloroflexia S PFAM Rhomboid family protein - - - - - - - - - - - - Rhomboid DYD1_k127_1346215_15 243230.DR_1114 5.248e-14 78.0 COG0071@1|root,COG0071@2|Bacteria,1WJV5@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O Belongs to the small heat shock protein (HSP20) family ibpA - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_1346215_8 309799.DICTH_0708 3.018e-59 209.0 COG1803@1|root,COG1803@2|Bacteria 2|Bacteria G methylglyoxal synthase activity mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992 MGS DYD1_k127_1346215_3 1283300.ATXB01000002_gene3052 2.878e-90 326.0 COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria,1XFY9@135618|Methylococcales 135618|Methylococcales S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth DYD1_k127_1346215_18 326427.Cagg_0442 5.668e-05 57.0 COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,377RQ@32061|Chloroflexia 32061|Chloroflexia M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_1346215_7 935863.AWZR01000007_gene259 4.241e-62 222.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1X3XJ@135614|Xanthomonadales 1236|Gammaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm2 - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD1_k127_1346215_13 926569.ANT_28850 4.442e-38 146.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein ycaO - - ko:K09136 - - - - ko00000,ko03009 - - - OsmC,YcaO DYD1_k127_1346215_17 1131269.AQVV01000002_gene1238 3.069e-07 60.0 COG3011@1|root,COG3011@2|Bacteria 2|Bacteria CH Protein conserved in bacteria - - - - - - - - - - - - DUF393 DYD1_k127_1346215_14 926569.ANT_14090 1.86e-22 105.0 COG1716@1|root,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination - - - - - - - - - - - - FHA,RDD,Yop-YscD_cpl DYD1_k127_1346215_1 926569.ANT_25980 1.057e-134 443.0 COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi 200795|Chloroflexi O NfeD-like C-terminal, partner-binding - - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD DYD1_k127_1346215_4 926569.ANT_00990 2.748e-84 286.0 COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi 200795|Chloroflexi M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_1346215_12 500633.CLOHIR_01184 2.597e-45 172.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,25QN9@186804|Peptostreptococcaceae 186801|Clostridia L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII DYD1_k127_1346215_6 926569.ANT_31200 3.929e-76 290.0 COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA DYD1_k127_1346215_0 1382304.JNIL01000001_gene3056 0.0 1124.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,2793N@186823|Alicyclobacillaceae 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06730 Aconitase,Aconitase_C DYD1_k127_1346215_10 1500257.JQNM01000019_gene2757 6.505e-48 188.0 COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Protein of unknown function (DUF2652) - - - - - - - - - - - - DUF2652,Polyketide_cyc2 DYD1_k127_1346215_11 864702.OsccyDRAFT_1898 9.814e-46 170.0 COG2944@1|root,COG2944@2|Bacteria,1G6V7@1117|Cyanobacteria,1HBR9@1150|Oscillatoriales 1117|Cyanobacteria K Helix-turn-helix - - - - - - - - - - - - HTH_3 DYD1_k127_1346215_9 398767.Glov_1844 3.025e-48 191.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria 28221|Deltaproteobacteria T GAF domain - - - - - - - - - - - - GAF,GGDEF DYD1_k127_1346215_16 751944.HALDL1_12465 1.622e-09 61.0 COG0075@1|root,arCOG00082@2157|Archaea,2XTWU@28890|Euryarchaeota,23S81@183963|Halobacteria 183963|Halobacteria E Serine-pyruvate aminotransferase archaeal aspartate aminotransferase spaT - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD1_k127_1351951_0 1382306.JNIM01000001_gene1668 8.932e-121 398.0 COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi 2|Bacteria S PFAM ABC transporter related - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran DYD1_k127_1351951_3 1313172.YM304_01530 1.481e-98 334.0 COG1744@1|root,COG1744@2|Bacteria,2IEKS@201174|Actinobacteria 201174|Actinobacteria S ABC transporter substrate-binding protein PnrA-like - - - - - - - - - - - - Bmp DYD1_k127_1351951_2 1487923.DP73_12465 3.39e-99 332.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,26193@186807|Peptococcaceae 186801|Clostridia U Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 DYD1_k127_1351951_4 913865.DOT_3610 2.088e-94 325.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,24DRF@186801|Clostridia,2646E@186807|Peptococcaceae 186801|Clostridia U Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 DYD1_k127_1351951_1 1304874.JAFY01000002_gene575 2.253e-107 363.0 COG1748@1|root,COG1748@2|Bacteria 2|Bacteria E saccharopine dehydrogenase activity lysDH - 1.4.1.18 ko:K19064 ko00960,ko01100,ko01110,map00960,map01100,map01110 - R00446,R02317 RC00062,RC00694 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP DYD1_k127_1351951_6 349521.HCH_00321 1.908e-81 280.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1XJZQ@135619|Oceanospirillales 135619|Oceanospirillales G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin DYD1_k127_1351951_8 502025.Hoch_3589 6.978e-44 165.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42RY9@68525|delta/epsilon subdivisions,2WW61@28221|Deltaproteobacteria,2Z2RX@29|Myxococcales 28221|Deltaproteobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc DYD1_k127_1351951_7 357808.RoseRS_3708 2.812e-46 181.0 COG0404@1|root,COG0404@2|Bacteria,2GBIM@200795|Chloroflexi,3780N@32061|Chloroflexia 32061|Chloroflexia H PFAM glycine cleavage T protein (aminomethyl transferase) - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C DYD1_k127_1351951_5 926569.ANT_23120 2.606e-85 293.0 COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi 200795|Chloroflexi M PFAM peptidase C60, sortase A and B - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase DYD1_k127_1351951_9 926569.ANT_09210 5.907e-23 106.0 COG0745@1|root,COG2114@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP,dCache_1,dCache_3 DYD1_k127_1374091_1 485913.Krac_0962 3.696e-61 233.0 COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi 200795|Chloroflexi KLT Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,Pkinase DYD1_k127_1374091_0 306281.AJLK01000118_gene4075 2.589e-81 280.0 COG1562@1|root,COG1562@2|Bacteria,1G0U6@1117|Cyanobacteria,1JICE@1189|Stigonemataceae 1117|Cyanobacteria I Squalene/phytoene synthase - - 2.5.1.21 ko:K00801 ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130 - R00702,R02872,R06223 RC00362,RC00796,RC02839 ko00000,ko00001,ko01000,ko01006 - - - SQS_PSY DYD1_k127_1374091_2 926554.KI912664_gene1577 2.764e-32 139.0 29XYR@1|root,30JRD@2|Bacteria,1WNBY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Lysyl oxidase - - - - - - - - - - - - Lysyl_oxidase DYD1_k127_1382642_0 570952.ATVH01000011_gene628 2.201e-28 132.0 2F4MK@1|root,33XB4@2|Bacteria,1NWZX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_1425384_0 316274.Haur_1430 5.461e-17 94.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia 200795|Chloroflexi T PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc DYD1_k127_1450060_2 926569.ANT_09200 2.354e-150 494.0 COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi 200795|Chloroflexi K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_1450060_1 926569.ANT_08710 5.126e-198 637.0 COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi 200795|Chloroflexi L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 DYD1_k127_1450060_0 926569.ANT_08730 0.0 1111.0 COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi 200795|Chloroflexi J Glycyl-tRNA synthetase alpha subunit glyQS - 6.1.1.14 ko:K14164 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko03016 - - - tRNA-synt_2e,tRNA_synt_2f DYD1_k127_1450060_6 926569.ANT_08620 1.201e-67 240.0 COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi 200795|Chloroflexi L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N DYD1_k127_1450060_5 661478.OP10G_0619 5.142e-72 263.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase DYD1_k127_1450060_7 926569.ANT_08630 7.408e-41 156.0 COG0295@1|root,COG0295@2|Bacteria,2G7AW@200795|Chloroflexi 200795|Chloroflexi F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 DYD1_k127_1450060_4 926569.ANT_08640 2.403e-86 301.0 COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi 200795|Chloroflexi S CBS domain containing protein - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 DYD1_k127_1450060_3 926569.ANT_08650 8.044e-147 477.0 COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi 200795|Chloroflexi M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 DYD1_k127_1450060_8 1297742.A176_00921 2.422e-17 94.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43AH2@68525|delta/epsilon subdivisions,2X5X2@28221|Deltaproteobacteria,2YUXP@29|Myxococcales 28221|Deltaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_1476701_1 1089552.KI911559_gene3181 1.383e-66 231.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2JPNE@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the ABC transporter superfamily - - - ko:K02052 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - ABC_tran,TOBE_2 DYD1_k127_1476701_0 1089552.KI911559_gene3182 2.014e-150 484.0 COG0687@1|root,COG0687@2|Bacteria,1MWG5@1224|Proteobacteria,2TTP2@28211|Alphaproteobacteria,2JRUN@204441|Rhodospirillales 204441|Rhodospirillales E Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_8 DYD1_k127_1480075_3 926550.CLDAP_20840 3.312e-105 345.0 COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_SAD DYD1_k127_1480075_5 926569.ANT_06130 2.632e-69 249.0 COG1376@1|root,COG1376@2|Bacteria 2|Bacteria D ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - DUF5011,LysM,YkuD DYD1_k127_1480075_7 926550.CLDAP_35190 7.41e-23 108.0 2FKJC@1|root,34C6D@2|Bacteria,2G9T3@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_1480075_0 926550.CLDAP_03390 5.988e-235 744.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi 200795|Chloroflexi C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - CCG,Fer4_8,Nitrate_red_gam DYD1_k127_1480075_6 926560.KE387023_gene2058 3.667e-32 137.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT DYD1_k127_1480075_8 1521187.JPIM01000031_gene2014 3.935e-21 104.0 COG1592@1|root,COG1592@2|Bacteria,2G7FW@200795|Chloroflexi,3760H@32061|Chloroflexia 32061|Chloroflexia C DinB superfamily - - - - - - - - - - - - DinB_2 DYD1_k127_1480075_4 867845.KI911784_gene1357 8.081e-105 352.0 COG1071@1|root,COG1071@2|Bacteria,2G6HY@200795|Chloroflexi,3754C@32061|Chloroflexia 32061|Chloroflexia C PFAM dehydrogenase, E1 component - - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD1_k127_1480075_1 326427.Cagg_2096 3.877e-139 452.0 COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi,374SG@32061|Chloroflexia 32061|Chloroflexia C PFAM Transketolase central region - - 1.2.4.4 ko:K00167 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_1480075_2 324602.Caur_1691 6.992e-129 424.0 COG0508@1|root,COG0508@2|Bacteria,2G5TB@200795|Chloroflexi,3759C@32061|Chloroflexia 32061|Chloroflexia C catalytic domain of components of various dehydrogenase complexes - - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_150312_15 1128421.JAGA01000002_gene1498 1.315e-75 267.0 COG1502@1|root,COG1502@2|Bacteria,2NQ5Z@2323|unclassified Bacteria 2|Bacteria I PLD-like domain - - 3.1.4.4 ko:K17717 ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110 - R01310,R02051,R07385 RC00017,RC00425 ko00000,ko00001,ko01000 - - - PLDc_2 DYD1_k127_150312_12 926569.ANT_25310 2.142e-83 289.0 COG1996@1|root,COG1996@2|Bacteria 2|Bacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - DUF4379 DYD1_k127_150312_13 926569.ANT_25300 1.521e-80 279.0 COG2888@1|root,COG2888@2|Bacteria 2|Bacteria J peptidyl-tyrosine sulfation ybeL - 1.17.4.1,4.6.1.1 ko:K00525,ko:K01768 ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213 M00053,M00695 R00089,R00434,R02017,R02018,R02019,R02024 RC00295,RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - DUF1451 DYD1_k127_150312_21 1379270.AUXF01000001_gene2649 3.338e-32 135.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Helix-turn-helix diphteria tox regulatory element - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA DYD1_k127_150312_2 926569.ANT_26930 4.491e-224 712.0 COG0370@1|root,COG0370@2|Bacteria 2|Bacteria P ferrous iron transmembrane transporter activity feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate DYD1_k127_150312_28 1235793.C809_01944 3.319e-06 56.0 COG1652@1|root,COG1652@2|Bacteria,1V78C@1239|Firmicutes,24JMB@186801|Clostridia,27NZ6@186928|unclassified Lachnospiraceae 186801|Clostridia S Lysin motif - - - - - - - - - - - - LysM DYD1_k127_150312_16 326427.Cagg_3321 6.824e-65 228.0 COG1943@1|root,COG1943@2|Bacteria,2G88H@200795|Chloroflexi,377A5@32061|Chloroflexia 32061|Chloroflexia L Transposase IS200 like - - - - - - - - - - - - - DYD1_k127_150312_10 1396141.BATP01000003_gene4874 2.041e-87 300.0 COG0167@1|root,COG0167@2|Bacteria,46S5W@74201|Verrucomicrobia,2IU2W@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Dihydroorotate dehydrogenase pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh DYD1_k127_150312_4 5693.XP_811679.1 5.717e-130 432.0 COG0461@1|root,KOG1377@2759|Eukaryota,3XSWC@5653|Kinetoplastida 5653|Kinetoplastida F Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase - - 2.4.2.10,4.1.1.23 ko:K01591,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase,Pribosyltran DYD1_k127_150312_20 1127134.NOCYR_0781 8.597e-37 143.0 COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria,4G1T9@85025|Nocardiaceae 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx DYD1_k127_150312_6 130081.XP_005704774.1 2.135e-124 407.0 COG0122@1|root,COG0458@1|root,KOG0370@2759|Eukaryota,KOG2875@2759|Eukaryota 2759|Eukaryota L 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity URA2 GO:0000050,GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006282,GO:0006284,GO:0006285,GO:0006289,GO:0006304,GO:0006355,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009889,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010605,GO:0016020,GO:0016021,GO:0016053,GO:0016363,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019627,GO:0019637,GO:0019692,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0031326,GO:0031974,GO:0031981,GO:0032356,GO:0032357,GO:0032991,GO:0033554,GO:0033683,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045007,GO:0045008,GO:0045738,GO:0045934,GO:0045984,GO:0046112,GO:0046386,GO:0046394,GO:0046434,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0051716,GO:0055086,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0070013,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0072529,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901135,GO:1901136,GO:1901291,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001141 2.1.3.2,3.5.2.3,4.2.99.18,6.3.5.5 ko:K01954,ko:K01955,ko:K03660,ko:K11540,ko:K11541,ko:K19656 ko00240,ko00250,ko01100,ko03410,map00240,map00250,map01100,map03410 M00051 R00256,R00575,R01395,R01397,R01993,R10948,R10949 RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314 ko00000,ko00001,ko00002,ko01000,ko01002,ko03036,ko03400 - - - CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,HhH-GPD,MGS,OGG_N,OTCace,OTCace_N DYD1_k127_150312_5 9978.XP_004582728.1 3.069e-126 414.0 COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa,3CS9A@33213|Bilateria,4804V@7711|Chordata,490QX@7742|Vertebrata,3J7SX@40674|Mammalia,35JF3@314146|Euarchontoglires 33208|Metazoa F Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase CAD GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 ko:K11540 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R01397,R01993,R10948,R10949 RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314 ko00000,ko00001,ko00002,ko01000,ko01002 - - - Amidohydro_1,CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS,OTCace,OTCace_N DYD1_k127_150312_25 1449126.JQKL01000002_gene1553 2.351e-24 109.0 COG0680@1|root,COG0680@2|Bacteria 2|Bacteria C spore germination hybD - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI DYD1_k127_150312_1 1379698.RBG1_1C00001G0047 2.809e-234 733.0 COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria 2|Bacteria C Nickel-dependent hydrogenase - - 1.8.98.5 ko:K14126 ko00680,map00680 - R00019,R11943 RC00011 ko00000,ko00001,ko01000 - - - NiFeSe_Hases DYD1_k127_150312_8 1379698.RBG1_1C00001G0048 2.259e-117 387.0 COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria 2|Bacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit - - 1.8.98.5 ko:K14128 ko00680,map00680 - R00019,R11943 RC00011 ko00000,ko00001,ko01000 - - - Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6 DYD1_k127_150312_18 429009.Adeg_2015 1.158e-50 189.0 COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales 186801|Clostridia C PFAM methyl-viologen-reducing hydrogenase delta subunit - - 1.8.98.5,1.8.98.6 ko:K14127 ko00680,map00680 - R00019,R11943,R11944 RC00011 ko00000,ko00001,ko01000 - - - FlpD,NADH_4Fe-4S DYD1_k127_150312_0 1121440.AUMA01000003_gene3114 3.09e-247 783.0 COG1148@1|root,COG1148@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria,2M898@213115|Desulfovibrionales 28221|Deltaproteobacteria C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4,FlpD,Pyr_redox_2 DYD1_k127_150312_14 1379698.RBG1_1C00001G0051 1.294e-75 269.0 COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria 2|Bacteria C Heterodisulfide reductase subunit B hdrB - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG DYD1_k127_150312_19 1449126.JQKL01000002_gene1547 2.349e-41 160.0 COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia 186801|Clostridia C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_8 DYD1_k127_150312_17 909663.KI867150_gene2881 1.33e-58 223.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42QJF@68525|delta/epsilon subdivisions,2WJ9D@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,Response_reg DYD1_k127_150312_9 269799.Gmet_1057 9.757e-92 327.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase HAMP - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,sCache_3_3 DYD1_k127_150312_24 237368.SCABRO_02485 4.098e-29 121.0 COG0745@1|root,COG0745@2|Bacteria 237368.SCABRO_02485|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_150312_26 572477.Alvin_0806 3.668e-23 108.0 COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,1SIG2@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Hydrogenase maturation protease vhtD - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI DYD1_k127_150312_3 572477.Alvin_0807 1.437e-177 580.0 COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,1WY2T@135613|Chromatiales 135613|Chromatiales C PFAM Nickel-dependent hydrogenase, large subunit - - - - - - - - - - - - NiFeSe_Hases DYD1_k127_150312_11 572477.Alvin_0808 1.134e-84 293.0 COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,1WYVW@135613|Chromatiales 135613|Chromatiales C NADH ubiquinone oxidoreductase, 20 Kd subunit - - - - - - - - - - - - Oxidored_q6 DYD1_k127_150312_7 572477.Alvin_0809 2.024e-120 397.0 COG0543@1|root,COG0543@2|Bacteria,1MV72@1224|Proteobacteria,1T4D8@1236|Gammaproteobacteria,1X2TA@135613|Chromatiales 135613|Chromatiales C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - - - - - - - - - - DHODB_Fe-S_bind,NAD_binding_1 DYD1_k127_150312_23 572477.Alvin_0810 3.6e-29 118.0 COG1143@1|root,COG1143@2|Bacteria,1QVAQ@1224|Proteobacteria,1T4SQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_22 DYD1_k127_1516813_2 926569.ANT_15400 1.553e-93 317.0 COG0667@1|root,COG0667@2|Bacteria,2G6QZ@200795|Chloroflexi 200795|Chloroflexi C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD1_k127_1516813_3 926550.CLDAP_29040 6.303e-85 291.0 COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi 200795|Chloroflexi S NAD-dependent epimerase dehydratase - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase DYD1_k127_1516813_1 926569.ANT_06860 6.962e-162 524.0 COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi 200795|Chloroflexi L PFAM IstB domain protein ATP-binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 DYD1_k127_1516813_5 485913.Krac_12129 1.81e-33 138.0 COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi 200795|Chloroflexi L TIGRFAM primosome, DnaD subunit - - - - - - - - - - - - DnaB_2 DYD1_k127_1516813_0 926569.ANT_06840 1.306e-186 594.0 COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi 200795|Chloroflexi L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C DYD1_k127_1516813_4 926569.ANT_06830 1.986e-47 176.0 COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi 200795|Chloroflexi S Bifunctional nuclease - - - ko:K08999 - - - - ko00000 - - - DNase-RNase DYD1_k127_1516813_6 1463936.JOJI01000012_gene6220 7.155e-19 90.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria 201174|Actinobacteria C CoA-binding domain protein acdA1 - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD1_k127_1523547_3 485913.Krac_1674 1.05e-87 313.0 COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi 200795|Chloroflexi K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2,SnoaL_2 DYD1_k127_1523547_1 1173029.JH980292_gene1248 4.448e-150 488.0 28HX6@1|root,2Z82X@2|Bacteria,1G2BW@1117|Cyanobacteria,1HAG9@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_1523547_5 1121272.KB903249_gene1664 1.618e-61 241.0 COG3292@1|root,COG3292@2|Bacteria,2I71F@201174|Actinobacteria,4DKYH@85008|Micromonosporales 201174|Actinobacteria T Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - DYD1_k127_1523547_0 443143.GM18_1319 0.0 3464.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria 28221|Deltaproteobacteria G glycosyltransferase 36 associated - - 2.4.1.20 ko:K00702,ko:K13688 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase DYD1_k127_1523547_9 269800.Tfu_0056 1.15e-11 77.0 COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2GIV0@201174|Actinobacteria,4EM40@85012|Streptosporangiales 201174|Actinobacteria KLT WD domain, G-beta repeat - - - - - - - - - - - - PD40,Pkinase,WD40 DYD1_k127_1523547_2 338966.Ppro_0754 4.14e-140 457.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43T9G@69541|Desulfuromonadales 28221|Deltaproteobacteria L helicase superfamily c-terminal domain rhlE-2 - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C DYD1_k127_1523547_6 926560.KE387023_gene1539 3.491e-28 130.0 2DXZ1@1|root,34790@2|Bacteria,1WN4B@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - DYD1_k127_1523547_7 926569.ANT_08190 6.03e-24 106.0 COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi 200795|Chloroflexi K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD1_k127_1523547_8 926569.ANT_22010 3.273e-13 74.0 COG1143@1|root,COG1143@2|Bacteria,2G9SP@200795|Chloroflexi 200795|Chloroflexi C 4Fe-4S binding domain - - - ko:K14091 - - - - ko00000 - - - Fer4 DYD1_k127_1523547_4 926569.ANT_22020 2.44e-64 223.0 COG1005@1|root,COG1005@2|Bacteria 2|Bacteria C quinone binding nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_1559146_1 926550.CLDAP_10830 1.408e-65 235.0 COG0765@1|root,COG0765@2|Bacteria,2G6IJ@200795|Chloroflexi 200795|Chloroflexi P Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 DYD1_k127_1559146_0 926569.ANT_12150 3.26e-67 240.0 COG0834@1|root,COG0834@2|Bacteria,2G6HE@200795|Chloroflexi 200795|Chloroflexi ET Bacterial periplasmic substrate-binding proteins - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD1_k127_1559146_2 796606.BMMGA3_15055 1.368e-05 55.0 COG1316@1|root,COG1316@2|Bacteria,1TQ9C@1239|Firmicutes,4HB29@91061|Bacilli,1ZB6K@1386|Bacillus 91061|Bacilli K Transcriptional regulator yvhJ - - - - - - - - - - - LytR_cpsA_psr DYD1_k127_1561386_5 479434.Sthe_0465 1.485e-55 205.0 COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,27Y19@189775|Thermomicrobia 189775|Thermomicrobia L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_1561386_2 926569.ANT_09840 2.551e-108 357.0 COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi 200795|Chloroflexi F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 DYD1_k127_1561386_8 926569.ANT_09850 3.781e-25 113.0 28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_1561386_7 926569.ANT_09860 3.505e-31 139.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase yyaR - - ko:K06889,ko:K19273 - - - - ko00000,ko01000,ko01504 - - - Acetyltransf_1 DYD1_k127_1561386_1 926569.ANT_09870 1.698e-149 494.0 COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi 200795|Chloroflexi K N-terminal 7TM region of histidine kinase - - - - - - - - - - - - HisKA_7TM DYD1_k127_1561386_4 926569.ANT_09880 2.616e-74 261.0 COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi 2|Bacteria J PFAM RNA binding S1 domain protein ispH - 1.17.7.4 ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 M00096,M00178 R05884,R08210 RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - - LYTB,S1 DYD1_k127_1561386_0 926569.ANT_09890 8.114e-194 629.0 COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi 200795|Chloroflexi D PFAM cell divisionFtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma DYD1_k127_1561386_6 926569.ANT_09900 1.083e-54 198.0 COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi 200795|Chloroflexi I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD1_k127_1561386_3 926569.ANT_09910 1.63e-75 267.0 COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi 200795|Chloroflexi M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD1_k127_1563246_4 316274.Haur_3851 2.416e-10 72.0 COG4842@1|root,COG4842@2|Bacteria 2|Bacteria S protein secretion by the type VII secretion system - - - - - - - - - - - - Ntox44,Peptidase_C2,WXG100 DYD1_k127_1563246_2 485913.Krac_10555 1.765e-74 256.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE,Response_reg DYD1_k127_1563246_1 485913.Krac_6032 2.729e-83 293.0 COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi 200795|Chloroflexi T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,GAF_3,HATPase_c,HisKA_3 DYD1_k127_1563246_5 316274.Haur_3851 7.425e-09 61.0 COG4842@1|root,COG4842@2|Bacteria 2|Bacteria S protein secretion by the type VII secretion system - - - - - - - - - - - - Ntox44,Peptidase_C2,WXG100 DYD1_k127_1563246_3 316274.Haur_2580 1.298e-35 149.0 COG0515@1|root,COG0515@2|Bacteria 316274.Haur_2580|- KLT protein kinase activity - - - - - - - - - - - - - DYD1_k127_1563246_0 316274.Haur_2581 0.0 1716.0 COG1674@1|root,COG1674@2|Bacteria,2G5Y3@200795|Chloroflexi,376BF@32061|Chloroflexia 32061|Chloroflexia D PFAM cell divisionFtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE DYD1_k127_1563246_6 316274.Haur_2582 4.302e-07 60.0 COG1716@1|root,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - DUF4234,FHA,GAF,GAF_2,Guanylate_cyc,HATPase_c,Yop-YscD_cpl DYD1_k127_1564062_4 234267.Acid_6492 4.924e-40 156.0 COG1832@1|root,COG1832@2|Bacteria,3Y566@57723|Acidobacteria 57723|Acidobacteria S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 DYD1_k127_1564062_2 926560.KE387023_gene2289 7.317e-105 377.0 COG3852@1|root,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c DYD1_k127_1564062_0 926560.KE387023_gene1698 2.605e-202 643.0 COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1WM1W@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus KOT FAD dependent oxidoreductase - - - - - - - - - - - - Pyr_redox_2,Response_reg DYD1_k127_1564062_7 948106.AWZT01000079_gene4291 6.741e-15 89.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae 28216|Betaproteobacteria T adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16,BTAD,Guanylate_cyc,Pkinase,SAM_1 DYD1_k127_1564062_1 316274.Haur_1430 1.396e-133 449.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia 200795|Chloroflexi T PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc DYD1_k127_1564062_5 1254432.SCE1572_12540 1.072e-36 161.0 COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2Z01S@29|Myxococcales 28221|Deltaproteobacteria CT Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - HEAT_2,TLC,cNMP_binding DYD1_k127_1564062_3 926569.ANT_22320 2.751e-81 285.0 COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi 200795|Chloroflexi S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG DYD1_k127_1564062_6 643648.Slip_0359 9.62e-18 90.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,42K2F@68298|Syntrophomonadaceae 186801|Clostridia J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX DYD1_k127_1564062_8 572546.Arcpr_1480 0.000672 51.0 COG3299@1|root,arCOG10307@2157|Archaea,2XX74@28890|Euryarchaeota,246S4@183980|Archaeoglobi 183980|Archaeoglobi S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J DYD1_k127_157659_0 158189.SpiBuddy_0713 5.418e-308 962.0 COG0021@1|root,COG0021@2|Bacteria 2|Bacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_N,XFP,XFP_N DYD1_k127_157659_3 158189.SpiBuddy_0718 2.004e-85 292.0 COG1082@1|root,COG1082@2|Bacteria,2JA6D@203691|Spirochaetes 203691|Spirochaetes G PFAM Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 DYD1_k127_157659_1 525904.Tter_2057 1.133e-102 343.0 COG1052@1|root,COG1052@2|Bacteria 2|Bacteria CH NAD binding MA20_14995 - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_157659_2 416591.Tlet_0192 2.233e-99 335.0 COG1012@1|root,COG1012@2|Bacteria,2GCJA@200918|Thermotogae 200918|Thermotogae C PFAM Aldehyde dehydrogenase - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_1593557_1 926550.CLDAP_37650 7.255e-112 368.0 COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi 200795|Chloroflexi C PFAM Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_1593557_0 926569.ANT_07650 3.131e-156 515.0 COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi 200795|Chloroflexi V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_1593557_3 926569.ANT_08780 4.749e-99 328.0 COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi 200795|Chloroflexi P Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_1593557_2 926569.ANT_07670 1.288e-105 364.0 COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi 200795|Chloroflexi M PFAM secretion protein HlyD family protein - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_1593557_6 562970.Btus_0552 7.71e-05 54.0 2CQ9E@1|root,32SKP@2|Bacteria,1V985@1239|Firmicutes,4HJAZ@91061|Bacilli,279ZM@186823|Alicyclobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_1593557_5 211114.JOEF01000007_gene865 1.182e-25 113.0 COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E3X3@85010|Pseudonocardiales 201174|Actinobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2,SnoaL_2 DYD1_k127_1593557_4 401526.TcarDRAFT_2302 9.821e-49 183.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4H2A8@909932|Negativicutes 909932|Negativicutes C glutamate synthase (NADPH) gltA - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,Pyr_redox_2 DYD1_k127_1608215_0 1380391.JIAS01000011_gene5162 5.695e-225 700.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TTWE@28211|Alphaproteobacteria,2JRBD@204441|Rhodospirillales 28211|Alphaproteobacteria E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C DYD1_k127_1608215_1 1380391.JIAS01000011_gene5161 2.183e-43 162.0 COG0449@1|root,COG0449@2|Bacteria,1R41J@1224|Proteobacteria,2TWKT@28211|Alphaproteobacteria 28211|Alphaproteobacteria M -glutamine - - - - - - - - - - - - GATase_6 DYD1_k127_1623563_1 635013.TherJR_1719 1.286e-122 405.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,26111@186807|Peptococcaceae 186801|Clostridia I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD1_k127_1623563_3 382464.ABSI01000010_gene3730 2.946e-28 122.0 COG4770@1|root,COG4770@2|Bacteria 2|Bacteria I CoA carboxylase activity pccA - 6.4.1.3 ko:K01965,ko:K02160 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00373,M00376,M00741 R00742,R01859 RC00040,RC00097,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 DYD1_k127_1623563_5 1121405.dsmv_2427 3.113e-24 111.0 COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MKPT@213118|Desulfobacterales 28221|Deltaproteobacteria F PFAM adenylate cyclase - - 4.6.1.1 ko:K05873 ko00230,map00230 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - CYTH DYD1_k127_1623563_0 926569.ANT_02690 3.056e-246 775.0 COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi 200795|Chloroflexi I TIGRFAM methylmalonyl-CoA mutase, large subunit - - 5.4.99.2 ko:K01847,ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase DYD1_k127_1623563_2 926569.ANT_02700 4.883e-47 179.0 COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi 200795|Chloroflexi E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 DYD1_k127_1623563_4 1122221.JHVI01000013_gene2748 2.977e-26 110.0 COG1943@1|root,COG1943@2|Bacteria,1WKUD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Transposase - - - - - - - - - - - - - DYD1_k127_1678893_10 317936.Nos7107_1630 1.339e-17 89.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus - - - - - - - - - - - - Ank,Ank_2,Cu_amine_oxidN1 DYD1_k127_1678893_0 316274.Haur_0889 3.557e-141 469.0 COG3934@1|root,COG3934@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - 3.2.1.78 ko:K19355 ko00051,map00051 - R01332 RC00467 ko00000,ko00001,ko01000 - - - Cellulase,DUF5060 DYD1_k127_1678893_6 1227349.C170_28093 1.178e-39 152.0 COG1051@1|root,COG1051@2|Bacteria,1V9D6@1239|Firmicutes,4HICH@91061|Bacilli,26YH7@186822|Paenibacillaceae 91061|Bacilli F Nudix hydrolase - - - - - - - - - - - - NUDIX DYD1_k127_1678893_4 861299.J421_0690 4.081e-42 160.0 2AYX9@1|root,31R2Z@2|Bacteria,1ZTNZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes S DinB superfamily - - - - - - - - - - - - DinB_2 DYD1_k127_1678893_5 1237149.C900_00291 8.231e-40 152.0 2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD1_k127_1678893_9 1408254.T458_09080 1.432e-33 133.0 COG2764@1|root,COG2764@2|Bacteria,1TQ8R@1239|Firmicutes,4HQUZ@91061|Bacilli,26SZ4@186822|Paenibacillaceae 91061|Bacilli S glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD1_k127_1678893_3 1385519.N801_01225 2.208e-45 171.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins yokL3 - 2.3.1.57 ko:K00657,ko:K07023 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_3 DYD1_k127_1678893_8 485913.Krac_3628 7.241e-36 143.0 COG5649@1|root,COG5649@2|Bacteria 2|Bacteria E Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD1_k127_1678893_7 1122138.AQUZ01000016_gene283 4.619e-37 145.0 COG5646@1|root,COG5646@2|Bacteria 2|Bacteria S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD1_k127_1678893_2 136273.GY22_04940 5.786e-47 179.0 COG0596@1|root,COG0596@2|Bacteria,2IDI0@201174|Actinobacteria,1WABF@1268|Micrococcaceae 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_1678893_11 1082931.KKY_2436 8.825e-08 55.0 2EFVW@1|root,339N3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1688688_0 243090.RB818 3.829e-140 458.0 COG3344@1|root,COG3344@2|Bacteria,2IZGP@203682|Planctomycetes 203682|Planctomycetes L Reverse transcriptase (RNA-dependent DNA polymerase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 DYD1_k127_1689570_23 1501230.ET33_22105 4.374e-23 102.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,26RYF@186822|Paenibacillaceae 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase DYD1_k127_1689570_7 1382356.JQMP01000003_gene1420 1.551e-84 296.0 COG0276@1|root,COG0276@2|Bacteria,2G6A2@200795|Chloroflexi,27XJN@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase DYD1_k127_1689570_4 479434.Sthe_2324 1.145e-137 446.0 COG0407@1|root,COG0407@2|Bacteria,2G5NU@200795|Chloroflexi,27XWH@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D DYD1_k127_1689570_12 661478.OP10G_0939 4.434e-56 212.0 COG3253@1|root,COG3253@2|Bacteria 2|Bacteria S peroxidase activity - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114 1.13.11.49 ko:K09162 - - - - ko00000,ko01000 - - - Chlor_dismutase DYD1_k127_1689570_5 1120973.AQXL01000117_gene375 1.415e-124 409.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli 91061|Bacilli C Fe-S oxidoreductases - - - ko:K22227 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM DYD1_k127_1689570_2 1122223.KB890688_gene1418 2.67e-141 459.0 COG0113@1|root,COG0113@2|Bacteria,1WINH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD DYD1_k127_1689570_17 1128421.JAGA01000001_gene2427 2.635e-45 179.0 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2NPBQ@2323|unclassified Bacteria 2|Bacteria H Tetrapyrrole (Corrin/Porphyrin) Methylases hemD GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 ko:K01719,ko:K01749,ko:K02303,ko:K13542,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084,R03165,R03194 RC00003,RC00871,RC01861,RC02317 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS15755,iJN678.hemD HEM4,TP_methylase DYD1_k127_1689570_9 521098.Aaci_1838 8.144e-77 273.0 COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,278YD@186823|Alicyclobacillaceae 91061|Bacilli H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC DYD1_k127_1689570_8 1125863.JAFN01000001_gene1123 3.609e-84 303.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH DYD1_k127_1689570_28 1382306.JNIM01000001_gene144 4.615e-15 84.0 COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi 200795|Chloroflexi L PFAM regulatory protein, MerR - - - - - - - - - - - - HTH_17 DYD1_k127_1689570_18 1500257.JQNM01000013_gene2829 2.698e-42 157.0 COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,4BFSX@82115|Rhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 DYD1_k127_1689570_21 1210884.HG799471_gene14625 5.845e-31 128.0 COG3832@1|root,COG3832@2|Bacteria,2J16I@203682|Planctomycetes 203682|Planctomycetes S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD1_k127_1689570_14 526227.Mesil_1024 1.51e-55 198.0 COG5646@1|root,COG5646@2|Bacteria,1WKCV@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S InterPro IPR014922 - - - - - - - - - - - - DUF1801 DYD1_k127_1689570_13 485913.Krac_1995 6.078e-56 198.0 COG5649@1|root,COG5649@2|Bacteria 2|Bacteria E Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD1_k127_1689570_0 886293.Sinac_4094 0.0 1097.0 COG0178@1|root,COG0178@2|Bacteria,2IYJN@203682|Planctomycetes 203682|Planctomycetes L ABC transporter - - - - - - - - - - - - ABC_tran DYD1_k127_1689570_27 1033810.HLPCO_002951 2.44e-18 91.0 COG1978@1|root,COG1978@2|Bacteria,2NRV0@2323|unclassified Bacteria 2|Bacteria S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - 1.21.4.1,1.21.4.2 ko:K10672,ko:K10794 ko00330,map00330 - R02825 RC00790 ko00000,ko00001,ko01000 - - - GRDB DYD1_k127_1689570_10 1121382.JQKG01000020_gene1208 2.3e-64 228.0 COG1028@1|root,COG1028@2|Bacteria 1121382.JQKG01000020_gene1208|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - DYD1_k127_1689570_1 1156937.MFUM_690030 6.321e-149 489.0 COG1249@1|root,COG1249@2|Bacteria,46SPB@74201|Verrucomicrobia,37FWI@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia C Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) merA - 1.16.1.1 ko:K00520 - - - - ko00000,ko01000 - - - HMA,Pyr_redox_2,Pyr_redox_dim DYD1_k127_1689570_6 1121946.AUAX01000008_gene7362 9.942e-119 399.0 COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4D9VG@85008|Micromonosporales 201174|Actinobacteria OT Pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_3,Response_reg DYD1_k127_1689570_29 1122179.KB890423_gene2354 1.611e-12 74.0 COG0062@1|root,COG0062@2|Bacteria,4P050@976|Bacteroidetes 976|Bacteroidetes G YjeF-related protein N-terminus - - - - - - - - - - - - YjeF_N DYD1_k127_1689570_26 945713.IALB_1961 1.101e-19 97.0 COG0062@1|root,COG0062@2|Bacteria 2|Bacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD1_k127_1689570_19 264732.Moth_0927 7.665e-39 148.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,42GS3@68295|Thermoanaerobacterales 186801|Clostridia O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_1689570_16 1146883.BLASA_0805 1.2e-53 198.0 2F7BB@1|root,342EN@2|Bacteria 2|Bacteria S F5/8 type C domain - - - - - - - - - - - - F5_F8_type_C DYD1_k127_1689570_11 867845.KI911784_gene3657 6.312e-57 211.0 COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia 32061|Chloroflexia H PFAM GTP cyclohydrolase I folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI DYD1_k127_1689570_20 1254432.SCE1572_05510 1.246e-31 132.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_1689570_25 1121380.JNIW01000054_gene3202 5.329e-20 96.0 2E8I5@1|root,332W5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1689570_3 324602.Caur_0549 3.518e-138 450.0 COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function (DUF3179) - - - - - - - - - - - - DUF3179 DYD1_k127_1689570_15 1125863.JAFN01000001_gene2629 2.781e-54 205.0 COG1626@1|root,COG1626@2|Bacteria,1R261@1224|Proteobacteria 1224|Proteobacteria G Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 DYD1_k127_1689570_22 383372.Rcas_1003 3.184e-23 108.0 COG0029@1|root,COG0029@2|Bacteria,2G5JM@200795|Chloroflexi,375AE@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the oxidation of L-aspartate to iminoaspartate - - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_1689570_33 383372.Rcas_1003 0.0009642 46.0 COG0029@1|root,COG0029@2|Bacteria,2G5JM@200795|Chloroflexi,375AE@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the oxidation of L-aspartate to iminoaspartate - - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_1689570_24 1236976.JCM16418_1512 2.599e-21 100.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,26R0R@186822|Paenibacillaceae 91061|Bacilli FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA DYD1_k127_169187_0 446470.Snas_0537 2.342e-166 544.0 COG3055@1|root,COG3055@2|Bacteria 2|Bacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - Big_2,Kelch_1,Kelch_3,Kelch_6 DYD1_k127_169187_1 1298864.AUEQ01000003_gene5596 2.388e-46 175.0 COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,235JB@1762|Mycobacteriaceae 201174|Actinobacteria G Aldolase fucA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 4.1.1.104,4.1.2.17,4.2.1.109,5.1.3.4 ko:K01628,ko:K03077,ko:K08964,ko:K22130 ko00040,ko00051,ko00053,ko00270,ko01100,ko01120,map00040,map00051,map00053,map00270,map01100,map01120 M00034,M00550 R02262,R05850,R07392 RC00603,RC00604,RC01479,RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II DYD1_k127_169187_2 698737.SLGD_01684 5.46e-08 55.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,4GY9V@90964|Staphylococcaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim DYD1_k127_1732252_0 926569.ANT_31250 1.817e-146 474.0 COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi 200795|Chloroflexi P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD1_k127_1732252_3 237368.SCABRO_01122 7.171e-66 233.0 COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes 203682|Planctomycetes P Plays a role in the regulation of phosphate uptake - - - ko:K02039 - - - - ko00000 - - - PhoU DYD1_k127_1732252_1 383372.Rcas_0586 1.327e-104 345.0 COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi,3751I@32061|Chloroflexia 32061|Chloroflexia P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran DYD1_k127_1732252_2 926569.ANT_02630 2.126e-103 347.0 COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi 200795|Chloroflexi P TIGRFAM phosphate binding protein pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 DYD1_k127_1732252_4 926569.ANT_02640 3.167e-19 92.0 COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi 200795|Chloroflexi P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 DYD1_k127_1734689_0 1128421.JAGA01000002_gene1294 5.001e-87 304.0 COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria 2|Bacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_1734689_1 118163.Ple7327_1591 1.663e-24 106.0 COG1432@1|root,COG1432@2|Bacteria,1G01P@1117|Cyanobacteria,3VIQD@52604|Pleurocapsales 1117|Cyanobacteria S NYN domain - - - - - - - - - - - - NYN DYD1_k127_1753747_12 1089550.ATTH01000002_gene48 1.644e-88 315.0 COG2128@1|root,COG2128@2|Bacteria,4NHD5@976|Bacteroidetes,1FK71@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Protein of unknown function (DUF3179) - - - - - - - - - - - - DUF3179 DYD1_k127_1753747_8 68170.KL590558_gene5392 6.544e-109 363.0 COG1409@1|root,COG3103@1|root,COG1409@2|Bacteria,COG4991@2|Bacteria,2GIT1@201174|Actinobacteria,4E0S4@85010|Pseudonocardiales 201174|Actinobacteria T Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos DYD1_k127_1753747_20 479434.Sthe_0449 1.091e-29 134.0 COG3858@1|root,COG3858@2|Bacteria,2G7HP@200795|Chloroflexi,27XZM@189775|Thermomicrobia 2|Bacteria S PFAM glycoside hydrolase, family 18 - - - - - - - - - - - - Amidase_2,Cu_amine_oxidN1,FAD_oxidored,Glyco_hydro_18,Hydrolase_2,Polysacc_deac_1,SLH DYD1_k127_1753747_4 219305.MCAG_00296 2.259e-141 463.0 COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4DAW3@85008|Micromonosporales 201174|Actinobacteria M Phosphoesterase family - - 3.1.4.3 ko:K01114 ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919 - R01312,R02027,R02052,R03332,R07381 RC00017,RC00425 ko00000,ko00001,ko01000,ko02042 - - - Phosphoesterase DYD1_k127_1753747_5 68170.KL590558_gene5388 5.548e-139 460.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 DYD1_k127_1753747_22 880072.Desac_2946 5.779e-27 122.0 COG0457@1|root,COG0457@2|Bacteria,1N5M0@1224|Proteobacteria,42U23@68525|delta/epsilon subdivisions,2WQ2H@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_1,TPR_8 DYD1_k127_1753747_24 1173027.Mic7113_6230 2.053e-06 59.0 2CID5@1|root,32WVT@2|Bacteria,1G8N7@1117|Cyanobacteria,1HCM4@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_1753747_21 404589.Anae109_2943 1.76e-27 126.0 COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,42RSB@68525|delta/epsilon subdivisions,2WNIX@28221|Deltaproteobacteria,2Z0FF@29|Myxococcales 28221|Deltaproteobacteria I Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat DYD1_k127_1753747_10 1121468.AUBR01000024_gene3018 6.982e-99 338.0 COG2768@1|root,COG2768@2|Bacteria,1TPRV@1239|Firmicutes,247PJ@186801|Clostridia,42FD8@68295|Thermoanaerobacterales 186801|Clostridia C Domain of unknown function (DUF2088) - - - - - - - - - - - - DUF2088,DUF362 DYD1_k127_1753747_23 304371.MCP_2904 4.807e-25 113.0 COG0269@1|root,arCOG00103@2157|Archaea,2XUYW@28890|Euryarchaeota,2N9CN@224756|Methanomicrobia 224756|Methanomicrobia F Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin fae-hps - 4.1.2.43,4.2.1.147 ko:K13812 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338,R08058 RC00421,RC00422,RC01583,RC01795 ko00000,ko00001,ko00002,ko01000 - - - Fae,OMPdecase DYD1_k127_1753747_14 1035193.HMPREF9073_00671 3.024e-72 255.0 COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1HZJ2@117743|Flavobacteriia 976|Bacteroidetes O prohibitin homologues - - - - - - - - - - - - Band_7 DYD1_k127_1753747_7 926550.CLDAP_35620 1.718e-116 395.0 COG1175@1|root,COG1175@2|Bacteria 2|Bacteria P transmembrane transport - - - ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316 ko02010,map02010 M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39 - - BPD_transp_1 DYD1_k127_1753747_9 926550.CLDAP_35610 2.127e-101 338.0 COG0395@1|root,COG0395@2|Bacteria 2|Bacteria P glycerophosphodiester transmembrane transport malF - - ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 - - BPD_transp_1 DYD1_k127_1753747_13 926550.CLDAP_35600 4.912e-81 299.0 COG1653@1|root,COG1653@2|Bacteria,2G8XC@200795|Chloroflexi 200795|Chloroflexi G COGs COG1653 ABC-type sugar transport system periplasmic component - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 DYD1_k127_1753747_17 1265505.ATUG01000002_gene2237 4.31e-40 165.0 COG0708@1|root,COG0708@2|Bacteria 2|Bacteria L double-stranded DNA 3'-5' exodeoxyribonuclease activity - - - - - - - - - - - - Exo_endo_phos,Laminin_G_3 DYD1_k127_1753747_19 397291.C804_00959 5.23e-30 133.0 COG2404@1|root,COG2404@2|Bacteria,1UFBQ@1239|Firmicutes,24C28@186801|Clostridia 186801|Clostridia S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - DYD1_k127_1753747_25 58123.JOFJ01000008_gene496 4.244e-06 53.0 COG2197@1|root,COG2197@2|Bacteria,2GJ5I@201174|Actinobacteria,4EPKH@85012|Streptosporangiales 201174|Actinobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_1753747_15 552811.Dehly_0442 1.411e-55 213.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Cytochrom_c3_2 DYD1_k127_1753747_18 1382356.JQMP01000001_gene1211 4.188e-35 139.0 COG1522@1|root,COG1522@2|Bacteria,2G77K@200795|Chloroflexi,27YBX@189775|Thermomicrobia 189775|Thermomicrobia K Transcription regulator - - - ko:K03718 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_AsnC-type DYD1_k127_1753747_1 358823.DF19_30360 5.065e-176 561.0 COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria 201174|Actinobacteria E Saccharopine dehydrogenase lys1 - 1.5.1.7 ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715 RC00217,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP DYD1_k127_1753747_2 485913.Krac_7969 3.936e-168 540.0 COG4992@1|root,COG4992@2|Bacteria 2|Bacteria E N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity patA - 2.6.1.11,2.6.1.17,2.6.1.82 ko:K00821,ko:K05830,ko:K09251 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00031,M00763,M00845 R01155,R02283,R04475,R09778,R10932 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_1753747_3 926550.CLDAP_05420 9.112e-161 518.0 COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi 200795|Chloroflexi H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_1753747_0 592015.HMPREF1705_01067 1.088e-188 611.0 COG2414@1|root,COG2414@2|Bacteria 2|Bacteria C aldehyde ferredoxin oxidoreductase activity - - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N DYD1_k127_1753747_27 309801.trd_1708 4.78e-05 49.0 COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia 189775|Thermomicrobia H MoaE protein - - 2.8.1.12 ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE,ThiS DYD1_k127_1753747_6 1382356.JQMP01000003_gene1906 2.407e-130 429.0 COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,27XG2@189775|Thermomicrobia 189775|Thermomicrobia P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.31 ko:K11072 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.11.1 - - ABC_tran,TOBE_2 DYD1_k127_1753747_11 1183438.GKIL_2741 6.806e-96 322.0 COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria 1117|Cyanobacteria P ABC-type spermidine putrescine transport system, permease component I potB - - ko:K02054,ko:K11071 ko02010,ko02024,map02010,map02024 M00193,M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11,3.A.1.11.1 - - BPD_transp_1 DYD1_k127_1753747_26 794903.OPIT5_10315 1.942e-05 55.0 COG1177@1|root,COG1177@2|Bacteria,46SW5@74201|Verrucomicrobia,3K7V7@414999|Opitutae 414999|Opitutae E Binding-protein-dependent transport system inner membrane component - - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 DYD1_k127_1765915_0 1121324.CLIT_8c01210 1.506e-182 587.0 COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae 186801|Clostridia C Aldehyde ferredoxin oxidoreductase, N-terminal domain - - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N DYD1_k127_1773950_9 479434.Sthe_0091 1.246e-41 158.0 COG1607@1|root,COG1607@2|Bacteria,2G7A6@200795|Chloroflexi 200795|Chloroflexi I PFAM thioesterase superfamily protein - - - - - - - - - - - - 4HBT DYD1_k127_1773950_1 926569.ANT_11650 2.493e-148 480.0 COG1239@1|root,COG1239@2|Bacteria,2G832@200795|Chloroflexi 200795|Chloroflexi H SMART AAA ATPase - - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - Mg_chelatase DYD1_k127_1773950_14 926550.CLDAP_22170 1.008e-23 102.0 COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi 200795|Chloroflexi IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD1_k127_1773950_2 926569.ANT_20510 5.843e-128 417.0 COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi 200795|Chloroflexi H Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh DYD1_k127_1773950_7 926569.ANT_20520 4.522e-76 271.0 COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi 200795|Chloroflexi H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt DYD1_k127_1773950_0 926569.ANT_15160 1.789e-256 804.0 COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi 200795|Chloroflexi KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PQQ_3,Pkinase DYD1_k127_1773950_8 926569.ANT_15150 2.381e-63 228.0 COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi 200795|Chloroflexi T SMART protein phosphatase 2C domain protein - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 DYD1_k127_1773950_6 926569.ANT_15140 1.083e-100 346.0 COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi 200795|Chloroflexi O PFAM von Willebrand factor type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA DYD1_k127_1773950_11 926569.ANT_15130 1.553e-34 141.0 COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi 200795|Chloroflexi T PFAM Forkhead-associated protein - - - - - - - - - - - - FHA DYD1_k127_1773950_12 926569.ANT_15120 2.477e-28 115.0 2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_1773950_4 926569.ANT_15110 3.736e-112 368.0 COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi 200795|Chloroflexi K Two component transcriptional regulator, winged helix family - - - ko:K07667,ko:K07668 ko02020,ko02024,map02020,map02024 M00454,M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_1773950_5 926569.ANT_14300 6.274e-106 348.0 COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi 200795|Chloroflexi K Two component transcriptional regulator, LuxR family - - - - - - - - - - - - GerE,Response_reg DYD1_k127_1773950_13 926569.ANT_15180 4.83e-25 116.0 COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 DYD1_k127_1773950_15 926569.ANT_15190 7.593e-20 104.0 2DTJR@1|root,33KPB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1773950_3 926569.ANT_15200 1.09e-114 381.0 COG0387@1|root,COG0387@2|Bacteria,2G6GE@200795|Chloroflexi 200795|Chloroflexi P PFAM sodium calcium exchanger membrane region - - - ko:K07300 - - - - ko00000,ko02000 2.A.19 - - Na_Ca_ex DYD1_k127_1773950_10 1173020.Cha6605_5319 1.779e-35 147.0 COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria 1117|Cyanobacteria I PFAM Diacylglycerol kinase, catalytic - - - - - - - - - - - - DAGK_cat DYD1_k127_17957_2 926569.ANT_02910 6.022e-153 495.0 COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - - - - - - - - - - Thy1 DYD1_k127_17957_5 926569.ANT_02900 4.319e-77 268.0 COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi 200795|Chloroflexi H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase DYD1_k127_17957_4 926569.ANT_02220 1.804e-86 296.0 COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi 200795|Chloroflexi J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C,TruB_C_2,TruB_N DYD1_k127_17957_6 926569.ANT_02230 6.945e-76 269.0 COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi 200795|Chloroflexi S PFAM phosphoesterase, RecJ domain protein - - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD1_k127_17957_7 926569.ANT_02240 1.295e-30 127.0 COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi 200795|Chloroflexi J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA DYD1_k127_17957_1 926569.ANT_02250 4.939e-248 779.0 COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi 200795|Chloroflexi J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N DYD1_k127_17957_8 926569.ANT_02260 6.463e-26 113.0 COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi 200795|Chloroflexi K Protein of unknown function (DUF448) - - - ko:K07742 - - - - ko00000 - - - DUF448 DYD1_k127_17957_3 1121468.AUBR01000029_gene1572 7.549e-110 379.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,42EQU@68295|Thermoanaerobacterales 186801|Clostridia K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 DYD1_k127_17957_0 926569.ANT_10870 9.014e-258 824.0 COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi 200795|Chloroflexi L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD1_k127_1808273_1 290397.Adeh_1439 2.742e-181 596.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria,2YUFW@29|Myxococcales 28221|Deltaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N,Glyco_hydro_2 DYD1_k127_1808273_2 1254432.SCE1572_21470 6.158e-147 496.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,42MJI@68525|delta/epsilon subdivisions,2WJQP@28221|Deltaproteobacteria,2YYGI@29|Myxococcales 28221|Deltaproteobacteria C 6-phosphogluconate dehydrogenase, C-terminal domain gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2620 6PGD,NAD_binding_2 DYD1_k127_1808273_0 671143.DAMO_0488 3.648e-222 698.0 COG0166@1|root,COG0166@2|Bacteria,2NP2H@2323|unclassified Bacteria 2|Bacteria G Belongs to the GPI family tal - 2.2.1.2,5.3.1.9 ko:K01810,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI,TAL_FSA DYD1_k127_1813284_1 926550.CLDAP_21600 1.58e-42 160.0 COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi 200795|Chloroflexi C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD1_k127_1813284_0 485913.Krac_12092 5.04e-253 798.0 COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi 200795|Chloroflexi I PFAM carboxyl transferase - - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD1_k127_1813284_2 1284352.AOIG01000030_gene160 4.515e-18 83.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,26SJC@186822|Paenibacillaceae 91061|Bacilli I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD1_k127_1853545_0 926569.ANT_03530 1.546e-286 890.0 COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi 200795|Chloroflexi L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD1_k127_1853545_1 1173028.ANKO01000042_gene858 5.613e-276 872.0 COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria 1117|Cyanobacteria S penicillin amidase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase DYD1_k127_1876776_22 686340.Metal_3637 2.221e-27 116.0 COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,1RNY2@1236|Gammaproteobacteria,1XDMR@135618|Methylococcales 135618|Methylococcales K response regulator - - - - - - - - - - - - Response_reg,Trans_reg_C DYD1_k127_1876776_15 1094980.Mpsy_1174 6.822e-42 169.0 COG0642@1|root,COG2203@1|root,arCOG02339@1|root,arCOG02376@1|root,arCOG03567@1|root,arCOG02339@2157|Archaea,arCOG02357@2157|Archaea,arCOG02376@2157|Archaea,arCOG03567@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,2NBNI@224756|Methanomicrobia 28890|Euryarchaeota T GAF domain - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_9,sCache_3_3 DYD1_k127_1876776_3 926569.ANT_13900 1.215e-92 328.0 COG0642@1|root,COG2205@2|Bacteria 926569.ANT_13900|- T PhoQ Sensor - - - - - - - - - - - - - DYD1_k127_1876776_4 926569.ANT_13890 2.953e-88 298.0 COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi 200795|Chloroflexi K Transcriptional regulatory protein, C terminal - - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_1876776_19 926569.ANT_13860 1.148e-33 139.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3,HTH_31 DYD1_k127_1876776_26 926569.ANT_13850 4.247e-17 90.0 COG0457@1|root,COG0457@2|Bacteria 926569.ANT_13850|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_1876776_16 926569.ANT_13840 4.618e-39 162.0 COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi 200795|Chloroflexi K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_1876776_23 999419.HMPREF1077_03696 1.287e-23 107.0 COG0642@1|root,COG0745@1|root,COG2207@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,4NG0B@976|Bacteroidetes,2FM88@200643|Bacteroidia 976|Bacteroidetes T Response regulator receiver domain protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y DYD1_k127_1876776_24 296591.Bpro_3898 3.547e-21 101.0 COG2199@1|root,COG2203@1|root,COG4251@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,2WHFW@28216|Betaproteobacteria,4AJWX@80864|Comamonadaceae 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg DYD1_k127_1876776_8 1449126.JQKL01000016_gene2859 3.597e-75 262.0 COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia 186801|Clostridia I Hydrolase, alpha beta domain protein - - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 DYD1_k127_1876776_17 1382356.JQMP01000003_gene1647 1.706e-36 155.0 COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia 189775|Thermomicrobia O DSBA-like thioredoxin domain - - - - - - - - - - - - Thioredoxin_4 DYD1_k127_1876776_9 926569.ANT_11270 2.629e-74 257.0 COG1811@1|root,COG1811@2|Bacteria,2G6S2@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 DYD1_k127_1876776_13 926569.ANT_11280 1.463e-49 182.0 COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi 200795|Chloroflexi S PFAM Cobalamin adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans DYD1_k127_1876776_18 1123065.ATWL01000007_gene3261 2.479e-34 138.0 COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria 201174|Actinobacteria L Competence protein ComEA comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB DYD1_k127_1876776_2 926569.ANT_12620 1.507e-94 317.0 COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi 200795|Chloroflexi L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD1_k127_1876776_27 1435356.Y013_24185 8.957e-07 58.0 COG3427@1|root,COG3427@2|Bacteria,2IRE2@201174|Actinobacteria,4G3AE@85025|Nocardiaceae 201174|Actinobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 DYD1_k127_1876776_10 204669.Acid345_0039 3.215e-60 218.0 COG0491@1|root,COG0491@2|Bacteria,3Y3M4@57723|Acidobacteria,2JI7X@204432|Acidobacteriia 204432|Acidobacteriia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_1876776_0 926569.ANT_25290 0.0 1276.0 COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi 200795|Chloroflexi U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD1_k127_1876776_21 926550.CLDAP_33490 2.39e-28 125.0 COG1657@1|root,COG1657@2|Bacteria,2G7AD@200795|Chloroflexi 200795|Chloroflexi I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - - DYD1_k127_1876776_12 926569.ANT_28690 7.798e-51 195.0 COG3868@1|root,COG3868@2|Bacteria,2G983@200795|Chloroflexi 200795|Chloroflexi S Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 DYD1_k127_1876776_5 926569.ANT_30510 1.137e-78 271.0 COG3118@1|root,COG3118@2|Bacteria,2G90Y@200795|Chloroflexi 200795|Chloroflexi O PFAM Thioredoxin domain - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin DYD1_k127_1876776_14 926569.ANT_30300 5.932e-46 169.0 2FH2K@1|root,348XD@2|Bacteria,2G93E@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_1876776_1 926569.ANT_30130 4.253e-96 325.0 COG1376@1|root,COG1376@2|Bacteria 2|Bacteria D ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - DUF5011,YkuD DYD1_k127_1876776_6 926569.ANT_30120 3.791e-78 273.0 COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi 200795|Chloroflexi M PFAM ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD DYD1_k127_1876776_11 926569.ANT_30110 1.391e-53 199.0 COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi 200795|Chloroflexi M PFAM cell wall hydrolase autolysin - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 DYD1_k127_1876776_7 321332.CYB_2315 1.867e-76 262.0 COG0031@1|root,COG0031@2|Bacteria,1GBK3@1117|Cyanobacteria,1H00H@1129|Synechococcus 1117|Cyanobacteria E Pyridoxal-phosphate dependent enzyme - - 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_1876776_25 309801.trd_1312 1.168e-20 93.0 COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia 189775|Thermomicrobia E Cysteine synthase - - 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738,ko:K12339 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03132,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_1876776_20 518766.Rmar_1678 2.743e-29 133.0 COG1310@1|root,COG1310@2|Bacteria,4NTI0@976|Bacteroidetes,1FJCV@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S JAB/MPN domain - - 3.13.1.6 ko:K21140 ko04122,map04122 - R11524 RC00064,RC00090 ko00000,ko00001,ko01000 - - - Prok-JAB DYD1_k127_1876776_28 321327.CYA_2470 6.107e-06 49.0 COG1977@1|root,COG1977@2|Bacteria,1GFB9@1117|Cyanobacteria,1H11X@1129|Synechococcus 1117|Cyanobacteria H ThiS family - - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD1_k127_1953779_0 861299.J421_1877 1.814e-165 526.0 COG1063@1|root,COG1063@2|Bacteria 2|Bacteria E alcohol dehydrogenase gcd - - - - - - - - - - - ADH_N,ADH_zinc_N,Glu_dehyd_C DYD1_k127_1953779_2 373903.Hore_13020 2.805e-37 160.0 COG4223@1|root,COG4223@2|Bacteria,1VK8G@1239|Firmicutes,24VZD@186801|Clostridia 186801|Clostridia DZ transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - - DYD1_k127_1953779_1 502025.Hoch_2631 4.287e-93 313.0 COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,42QCJ@68525|delta/epsilon subdivisions,2WKE7@28221|Deltaproteobacteria,2YUF8@29|Myxococcales 28221|Deltaproteobacteria G Glycosyl hydrolases family 15 - - - - - - - - - - - - DUF547,Glyco_hydro_15 DYD1_k127_2017314_3 1382356.JQMP01000001_gene709 6.569e-08 55.0 COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi,27YXH@189775|Thermomicrobia 189775|Thermomicrobia L Formamidopyrimidine-DNA glycosylase H2TH domain - - - - - - - - - - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD1_k127_2017314_2 1166018.FAES_1168 2.197e-34 141.0 COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,47MUD@768503|Cytophagia 976|Bacteroidetes S PFAM MgtC SapB transporter - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC DYD1_k127_2017314_0 95619.PM1_0225415 5.736e-185 593.0 COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,1RRN8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG0277 FAD FMN-containing dehydrogenases ygcU - 2.5.1.26 ko:K00803 ko00565,ko01100,ko04146,map00565,map01100,map04146 - R04311 RC00020,RC02886 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 DYD1_k127_2017314_1 378806.STAUR_5598 4.467e-165 534.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C DYD1_k127_2053749_4 1408254.T458_21085 2.412e-47 173.0 COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,4HN60@91061|Bacilli,26WT8@186822|Paenibacillaceae 91061|Bacilli G Mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 DYD1_k127_2053749_2 324602.Caur_2883 1.237e-80 274.0 COG1011@1|root,COG1011@2|Bacteria,2G7B3@200795|Chloroflexi,376JH@32061|Chloroflexia 32061|Chloroflexia S HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 DYD1_k127_2053749_3 1122138.AQUZ01000004_gene1019 3.206e-51 192.0 COG0596@1|root,COG0596@2|Bacteria,2I26T@201174|Actinobacteria 201174|Actinobacteria S Belongs to the peptidase S33 family pip - 3.4.11.5,3.5.1.101 ko:K01259,ko:K18457 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_2053749_1 582515.KR51_00018110 1.654e-115 386.0 COG4974@1|root,COG4974@2|Bacteria,1G224@1117|Cyanobacteria 1117|Cyanobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase DYD1_k127_2053749_0 42256.RradSPS_0067 1.182e-130 432.0 COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4CPS2@84995|Rubrobacteria 84995|Rubrobacteria F Amidohydrolase family - - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 DYD1_k127_2053749_5 926569.ANT_17260 6.569e-08 55.0 COG0161@1|root,COG0161@2|Bacteria 2|Bacteria H adenosylmethionine-8-amino-7-oxononanoate transaminase activity - - 2.6.1.55 ko:K15372 ko00410,ko00430,ko01100,map00410,map00430,map01100 - R00908,R01684 RC00006,RC00062 ko00000,ko00001,ko01000 - - - Aminotran_3 DYD1_k127_2062113_11 742743.HMPREF9453_01425 1.658e-07 55.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4H56U@909932|Negativicutes 909932|Negativicutes J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM DYD1_k127_2062113_9 479434.Sthe_1867 1.085e-14 81.0 COG1837@1|root,COG1837@2|Bacteria,2G9VQ@200795|Chloroflexi,27YME@189775|Thermomicrobia 189775|Thermomicrobia S KH domain - - - ko:K06960 - - - - ko00000 - - - KH_4 DYD1_k127_2062113_6 926569.ANT_16040 2.931e-28 122.0 COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi 200795|Chloroflexi J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 DYD1_k127_2062113_3 926569.ANT_11400 4.339e-95 331.0 COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi 200795|Chloroflexi D Belongs to the SEDS family - - - - - - - - - - - - FTSW_RODA_SPOVE DYD1_k127_2062113_1 926569.ANT_11390 1.534e-118 387.0 COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates mtnP - 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 DYD1_k127_2062113_10 309801.trd_0616 3.868e-14 82.0 COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi,27YBI@189775|Thermomicrobia 189775|Thermomicrobia T Forkhead associated domain - - - - - - - - - - - - FHA DYD1_k127_2062113_5 326427.Cagg_1633 2.903e-39 156.0 COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia 32061|Chloroflexia T PFAM Forkhead-associated protein - - - - - - - - - - - - DUF3662,FHA DYD1_k127_2062113_7 926569.ANT_11370 1.085e-22 108.0 COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi 200795|Chloroflexi T PFAM Forkhead-associated protein - - - - - - - - - - - - DUF3662,FHA DYD1_k127_2062113_8 497965.Cyan7822_1195 1.638e-18 92.0 COG1371@1|root,COG1371@2|Bacteria,1G81W@1117|Cyanobacteria,3KK0K@43988|Cyanothece 1117|Cyanobacteria S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease DYD1_k127_2062113_0 118163.Ple7327_0388 8.44e-218 684.0 COG1690@1|root,COG1690@2|Bacteria,1G0YE@1117|Cyanobacteria 1117|Cyanobacteria L family UPF0027 rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB DYD1_k127_2062113_2 926550.CLDAP_22390 1.851e-118 404.0 COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b DYD1_k127_2062113_4 1254432.SCE1572_09415 4.242e-58 211.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2YUZM@29|Myxococcales 28221|Deltaproteobacteria F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD1_k127_2062134_7 350688.Clos_0873 9.299e-18 84.0 COG0074@1|root,COG0074@2|Bacteria,1UJ4F@1239|Firmicutes,24AQG@186801|Clostridia,36HIH@31979|Clostridiaceae 186801|Clostridia C Protein of unknown function (DUF1116) - - - ko:K02381 - - - - ko00000 - - - CoA_binding,DUF1116,Ligase_CoA DYD1_k127_2062134_0 1123279.ATUS01000004_gene3041 1.384e-111 381.0 COG0074@1|root,COG0074@2|Bacteria,1MWWN@1224|Proteobacteria,1RME7@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Membrane protein FdrA fdrA GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006928,GO:0008150,GO:0009361,GO:0009987,GO:0032991,GO:0040011,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588,GO:1902494 - ko:K02381 - - - - ko00000 - - - CoA_binding,Ligase_CoA DYD1_k127_2062134_8 911008.GLAD_01356 9.8e-09 58.0 COG1304@1|root,COG1304@2|Bacteria,1QWBP@1224|Proteobacteria,1T2T0@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Protein of unknown function (DUF1116) yahG - - - - - - - - - - - DUF1116 DYD1_k127_2062134_9 700598.Niako_3128 2.137e-07 58.0 2EIK5@1|root,33CBF@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2062134_6 479434.Sthe_2298 3.423e-29 125.0 COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,27Y88@189775|Thermomicrobia 189775|Thermomicrobia S Cobalamin adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans DYD1_k127_2062134_2 264732.Moth_0467 9.105e-79 271.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,42G07@68295|Thermoanaerobacterales 186801|Clostridia P ATPases associated with a variety of cellular activities - - - ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - ABC_tran DYD1_k127_2062134_4 706587.Desti_5345 3.537e-49 190.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,42SE1@68525|delta/epsilon subdivisions,2WPX3@28221|Deltaproteobacteria,2MRIM@213462|Syntrophobacterales 28221|Deltaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02050,ko:K15552 ko00920,ko02010,map00920,map02010 M00188,M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4 - - BPD_transp_1 DYD1_k127_2062134_5 596152.DesU5LDRAFT_0350 1.382e-32 140.0 COG0715@1|root,COG0715@2|Bacteria,1RHDX@1224|Proteobacteria,42V6G@68525|delta/epsilon subdivisions,2WRZJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - iAF987.Gmet_0996 NMT1_2 DYD1_k127_2062134_1 589924.Ferp_1747 1.854e-81 276.0 COG5012@1|root,arCOG02028@2157|Archaea,2XXFQ@28890|Euryarchaeota,2479U@183980|Archaeoglobi 183980|Archaeoglobi S B12 binding domain - - - - - - - - - - - - B12-binding,B12-binding_2 DYD1_k127_2062134_3 589924.Ferp_1746 3.846e-53 191.0 COG0407@1|root,arCOG03323@2157|Archaea,2XV21@28890|Euryarchaeota 28890|Euryarchaeota H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 2.1.1.246,2.1.1.247,4.1.1.37 ko:K01599,ko:K14080,ko:K14082 ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200 M00121,M00356,M00563 R03197,R04972,R09098,R09124,R09998,R09999,R10000 RC00035,RC00556,RC00732,RC00872,RC01144,RC02440,RC02984,RC02985,RC02986 ko00000,ko00001,ko00002,ko01000 - - - URO-D DYD1_k127_2066046_0 160488.PP_4043 1.588e-42 162.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1YVYF@136845|Pseudomonas putida group 1236|Gammaproteobacteria G 6-phosphogluconate dehydrogenase gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 DYD1_k127_2066046_2 1122917.KB899663_gene2772 1.988e-18 93.0 2DCFK@1|root,2ZDY1@2|Bacteria,1W5KF@1239|Firmicutes,4HZTU@91061|Bacilli,26ZEH@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_2066046_1 383372.Rcas_2295 1.213e-26 122.0 COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia 32061|Chloroflexia D Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 DYD1_k127_207153_0 926569.ANT_19370 1.669e-70 254.0 COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi 200795|Chloroflexi M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 DYD1_k127_2098036_1 926569.ANT_17720 2.923e-117 389.0 COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi 200795|Chloroflexi J PFAM tRNA synthetase class II (G H P and S) hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD1_k127_2098036_0 926569.ANT_18510 3.096e-157 516.0 COG2986@1|root,COG2986@2|Bacteria,2G66R@200795|Chloroflexi 200795|Chloroflexi E PFAM phenylalanine histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic DYD1_k127_2098036_2 765420.OSCT_3196 3.991e-59 229.0 COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia 200795|Chloroflexi KLT Serine threonine protein kinase - - - - - - - - - - - - Pkinase DYD1_k127_2098036_3 1121106.JQKB01000037_gene664 7.837e-17 87.0 COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,2U9GD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - MOSC DYD1_k127_2122915_1 926569.ANT_14520 6.482e-71 250.0 COG3608@1|root,COG3608@2|Bacteria,2G71G@200795|Chloroflexi 200795|Chloroflexi S succinylglutamate desuccinylase aspartoacylase - - - ko:K07402 - - - - ko00000 - - - - DYD1_k127_2122915_2 926569.ANT_15370 2.311e-60 228.0 COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi 200795|Chloroflexi S 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD1_k127_2122915_4 1047013.AQSP01000139_gene2341 8.4e-26 114.0 COG2068@1|root,COG2068@2|Bacteria,2NPK5@2323|unclassified Bacteria 2|Bacteria S 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase mocA GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 ko:K07141,ko:K19190 ko00760,ko00790,ko01120,map00760,map00790,map01120 - R10131,R10132,R11582 RC03053 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_3649,iB21_1397.B21_02672,iECABU_c1320.ECABU_c31580,iECBD_1354.ECBD_0860,iECB_1328.ECB_02710,iECD_1391.ECD_02710,iEcHS_1320.EcHS_A3037 HD,HTH_1,NTP_transf_3 DYD1_k127_2122915_0 1521187.JPIM01000035_gene3399 7.243e-241 759.0 COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,374WK@32061|Chloroflexia 32061|Chloroflexia J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon DYD1_k127_2122915_3 706587.Desti_1467 1.257e-37 145.0 COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,430JJ@68525|delta/epsilon subdivisions,2WVQQ@28221|Deltaproteobacteria,2MRZH@213462|Syntrophobacterales 28221|Deltaproteobacteria S Cyclophilin-like - - - ko:K09143 - - - - ko00000 - - - Cyclophil_like DYD1_k127_2143748_10 525904.Tter_0441 4.091e-22 105.0 COG2385@1|root,COG2385@2|Bacteria,2NRF5@2323|unclassified Bacteria 2|Bacteria D Stage II sporulation protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Amidase_2,Amidase_3,ChW,SpoIID DYD1_k127_2143748_2 926550.CLDAP_17770 9.38e-194 612.0 COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N DYD1_k127_2143748_8 316274.Haur_3323 4.355e-30 124.0 COG1051@1|root,COG1694@1|root,COG1051@2|Bacteria,COG1694@2|Bacteria,2G9Y9@200795|Chloroflexi,377WH@32061|Chloroflexia 32061|Chloroflexia F MazG-like family - - - - - - - - - - - - MazG-like DYD1_k127_2143748_6 1128421.JAGA01000001_gene2082 5.008e-45 175.0 COG2129@1|root,COG2129@2|Bacteria 2|Bacteria L metallophosphoesterase Z012_09970 - - - - - - - - - - - Metallophos,Metallophos_2 DYD1_k127_2143748_5 1128421.JAGA01000001_gene2083 1.004e-66 243.0 COG1475@1|root,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria 2|Bacteria K DNA binding - - - - - - - - - - - - DUF4032,ParBc DYD1_k127_2143748_12 223184.AS25_10770 4.97e-05 55.0 COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,1W8VI@1268|Micrococcaceae 201174|Actinobacteria G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin DYD1_k127_2143748_7 926569.ANT_14050 2.161e-34 149.0 COG1611@1|root,COG1611@2|Bacteria 2|Bacteria S cytokinin biosynthetic process - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD1_k127_2143748_1 926569.ANT_10600 1.445e-234 732.0 COG0442@1|root,COG0442@2|Bacteria,2G636@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b DYD1_k127_2143748_9 926569.ANT_10580 9.522e-28 114.0 COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi 200795|Chloroflexi J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 DYD1_k127_2143748_0 926569.ANT_10570 3.148e-311 970.0 COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi 200795|Chloroflexi J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 DYD1_k127_2143748_4 926569.ANT_14100 4.036e-68 250.0 COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi 200795|Chloroflexi S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD1_k127_2143748_3 1128421.JAGA01000002_gene1337 7.323e-87 303.0 COG2242@1|root,COG2242@2|Bacteria 2|Bacteria H protein methyltransferase activity - - 2.1.1.242,2.1.1.303,2.1.1.319 ko:K11434,ko:K15984,ko:K20421 ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922 M00830 R10963,R11216,R11217,R11219 RC00003,RC00392,RC02120,RC03388,RC03390 ko00000,ko00001,ko00002,ko01000,ko03009,ko03036 - - - DOT1,Methyltransf_21,Methyltransf_25 DYD1_k127_2153726_1 926569.ANT_07670 7.127e-19 98.0 COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi 200795|Chloroflexi M PFAM secretion protein HlyD family protein - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_2153726_0 765420.OSCT_1742 9.109e-147 492.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_2174774_5 930171.Asphe3_01580 3.249e-38 146.0 COG4274@1|root,COG4274@2|Bacteria,2IJ0R@201174|Actinobacteria,1WBDV@1268|Micrococcaceae 201174|Actinobacteria S GYD domain - - - - - - - - - - - - GYD DYD1_k127_2174774_2 926569.ANT_02470 7.701e-125 409.0 COG1744@1|root,COG1744@2|Bacteria,2G8E5@200795|Chloroflexi 200795|Chloroflexi S ABC transporter substrate-binding protein PnrA-like - - - ko:K07335 - - - - ko00000 - - - Bmp DYD1_k127_2174774_0 926569.ANT_02460 2.618e-166 537.0 COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi 2|Bacteria S PFAM ABC transporter related - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran DYD1_k127_2174774_1 926569.ANT_02450 4.542e-131 426.0 COG4603@1|root,COG4603@2|Bacteria,2G8J7@200795|Chloroflexi 200795|Chloroflexi S Branched-chain amino acid transport system / permease component - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 DYD1_k127_2174774_3 926569.ANT_02440 1.737e-121 397.0 COG1079@1|root,COG1079@2|Bacteria,2G8PS@200795|Chloroflexi 200795|Chloroflexi S Branched-chain amino acid transport system / permease component - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 DYD1_k127_2174774_4 1088721.NSU_1615 9.292e-61 216.0 COG1432@1|root,COG1432@2|Bacteria,1RJ15@1224|Proteobacteria,2UCYU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S NYN domain - - - - - - - - - - - - NYN DYD1_k127_2174774_6 1200792.AKYF01000001_gene3905 7.002e-28 122.0 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,26Y8P@186822|Paenibacillaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD DYD1_k127_2189344_2 1121448.DGI_1138 0.0001373 48.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,2M81T@213115|Desulfovibrionales 28221|Deltaproteobacteria L PFAM DNA polymerase III, beta chain dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 DYD1_k127_2189344_0 1150398.JIBJ01000026_gene27 1.079e-121 416.0 COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,1W8BJ@1268|Micrococcaceae 201174|Actinobacteria S ABC1 family - - - - - - - - - - - - ABC1 DYD1_k127_2189344_1 926569.ANT_31250 5.78e-102 337.0 COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi 200795|Chloroflexi P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD1_k127_220031_6 1379698.RBG1_1C00001G1219 4.904e-37 145.0 COG1943@1|root,COG1943@2|Bacteria 2|Bacteria L Transposase - - - - - - - - - - - - Y1_Tnp DYD1_k127_220031_8 926554.KI912647_gene1816 1.563e-16 86.0 COG3427@1|root,COG3427@2|Bacteria,1WMX6@1297|Deinococcus-Thermus 2|Bacteria S Carbon monoxide dehydrogenase subunit G (CoxG) - - - ko:K09386 - - - - ko00000 - - - COXG DYD1_k127_220031_3 926550.CLDAP_27990 5.455e-106 356.0 COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi 200795|Chloroflexi I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD1_k127_220031_1 562970.Btus_0349 1.641e-146 474.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HABI@91061|Bacilli,279GP@186823|Alicyclobacillaceae 91061|Bacilli C CoA-transferase family III - - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 DYD1_k127_220031_4 1298867.AUES01000006_gene345 3.442e-76 266.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JUB1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - - - - - - - - - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_220031_5 1382356.JQMP01000003_gene1477 5.72e-70 256.0 COG2080@1|root,COG2080@2|Bacteria,2GBQV@200795|Chloroflexi,27Y9S@189775|Thermomicrobia 189775|Thermomicrobia C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_220031_2 795797.C497_05402 3.607e-139 458.0 COG0154@1|root,arCOG01717@2157|Archaea,2XV02@28890|Euryarchaeota,23TIC@183963|Halobacteria 183963|Halobacteria J Amidase - - - - - - - - - - - - Amidase DYD1_k127_220031_0 926569.ANT_05660 5.613e-168 548.0 COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi 200795|Chloroflexi C CoA-ligase - - - ko:K02381 - - - - ko00000 - - - CoA_binding,Ligase_CoA DYD1_k127_220031_7 158189.SpiBuddy_2606 3.68e-24 102.0 COG0074@1|root,COG0074@2|Bacteria,2J9PD@203691|Spirochaetes 203691|Spirochaetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit - - - - - - - - - - - - CoA_binding,DUF1116,Ligase_CoA DYD1_k127_2205842_0 479434.Sthe_0996 4.938e-104 342.0 COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi,27XI2@189775|Thermomicrobia 189775|Thermomicrobia C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family - - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10 DYD1_k127_2205842_1 876269.ARWA01000001_gene2144 9.413e-58 222.0 COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,3N9KG@45404|Beijerinckiaceae 28211|Alphaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,Response_reg DYD1_k127_2205842_2 926569.ANT_15080 5.14e-22 112.0 COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi 2|Bacteria S Ig-like domain from next to BRCA1 gene - - - - - - - - - - - - DUF11,N_BRCA1_IG DYD1_k127_2205842_4 9713.XP_006751653.1 5.066e-10 73.0 KOG4351@1|root,KOG4351@2759|Eukaryota,38HHX@33154|Opisthokonta,3B9X5@33208|Metazoa,3CU75@33213|Bilateria,4841R@7711|Chordata,490A6@7742|Vertebrata,3J9B2@40674|Mammalia,3EI89@33554|Carnivora 33208|Metazoa S Chromosome 6 open reading frame 106 C6orf106 GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919 - - - - - - - - - - N_BRCA1_IG,UBA_4 DYD1_k127_2205842_3 1219045.BV98_003047 1.155e-15 92.0 COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales 204457|Sphingomonadales S amine dehydrogenase activity - - - - - - - - - - - - - DYD1_k127_2220211_2 652103.Rpdx1_1151 1.677e-113 372.0 COG0559@1|root,COG0559@2|Bacteria,1R5BB@1224|Proteobacteria,2TT61@28211|Alphaproteobacteria,3JSC1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component MA20_39775 - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_2220211_0 172088.AUGA01000006_gene8177 5.782e-204 640.0 COG0683@1|root,COG0683@2|Bacteria,1MUZU@1224|Proteobacteria,2TS7Z@28211|Alphaproteobacteria,3JR4F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Periplasmic binding protein domain MA20_39780 - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_2220211_1 1038860.AXAP01000005_gene8037 1.567e-127 416.0 COG4177@1|root,COG4177@2|Bacteria,1MX6P@1224|Proteobacteria,2TU00@28211|Alphaproteobacteria,3JUC7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component MA20_39785 - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_2220211_3 1304877.KI519400_gene668 2.945e-10 62.0 COG4674@1|root,COG4674@2|Bacteria,1PHYH@1224|Proteobacteria,2TTUI@28211|Alphaproteobacteria,3JVBS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ATPases associated with a variety of cellular activities MA20_08750 - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD1_k127_2221294_1 1283283.ATXA01000001_gene587 2.222e-21 102.0 COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria 201174|Actinobacteria M Choline ethanolamine kinase - - - - - - - - - - - - APH,Choline_kinase DYD1_k127_2221294_0 345341.KUTG_02723 2.065e-201 652.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales 201174|Actinobacteria E FAD dependent oxidoreductase central domain - - 1.5.3.19 ko:K19191 ko00760,ko01120,map00760,map01120 - R10102 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO,FAO_M,GCV_T,GCV_T_C DYD1_k127_22717_7 926569.ANT_31610 1.876e-65 244.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process wzx - - ko:K16694 - - - - ko00000,ko02000 2.A.66.2.6 - - Polysacc_synt_3 DYD1_k127_22717_5 926569.ANT_00620 7.051e-87 300.0 COG0438@1|root,COG0438@2|Bacteria,2G9D7@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 DYD1_k127_22717_9 472759.Nhal_2169 1.118e-55 216.0 28M01@1|root,2ZAF6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PMT_2 DYD1_k127_22717_0 926569.ANT_09960 1.701e-168 535.0 COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi 200795|Chloroflexi M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd DYD1_k127_22717_3 926569.ANT_06170 5.162e-134 440.0 COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi 200795|Chloroflexi M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_22717_6 1502851.FG93_04279 9.98e-84 291.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2U963@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_22717_13 685778.AORL01000010_gene3125 0.0006177 53.0 COG5265@1|root,COG5265@2|Bacteria,1MWU5@1224|Proteobacteria,2U7S8@28211|Alphaproteobacteria,2K15C@204457|Sphingomonadales 204457|Sphingomonadales O HPr kinase - - - - - - - - - - - - - DYD1_k127_22717_12 926569.ANT_06160 8.159e-39 161.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_22717_11 926569.ANT_06280 5.605e-43 164.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - DUF4388,HTH_24,MarR_2 DYD1_k127_22717_2 926569.ANT_06290 9.849e-152 484.0 COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi 200795|Chloroflexi GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase DYD1_k127_22717_4 234267.Acid_4640 5.3e-100 336.0 COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria 57723|Acidobacteria GM ABC-2 type transporter - - - ko:K09690 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC2_membrane DYD1_k127_22717_1 926569.ANT_06310 3.036e-163 537.0 COG1134@1|root,COG1134@2|Bacteria 2|Bacteria GM teichoic acid transport - - 3.6.3.38 ko:K01990,ko:K09689,ko:K09691 ko02010,map02010 M00249,M00250,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.101,3.A.1.103 - - ABC_tran,Wzt_C DYD1_k127_2330299_0 926560.KE387023_gene2224 6.415e-64 226.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase eryCVI GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983 2.1.1.234 ko:K13311,ko:K13326,ko:K21335 ko00523,ko01130,map00523,map01130 M00797,M00800 R06427,R11045,R11476 RC00003,RC01515,RC02262 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_25 DYD1_k127_2330299_1 118161.KB235922_gene4768 1.064e-35 141.0 COG0824@1|root,COG0824@2|Bacteria,1G6Q4@1117|Cyanobacteria,3VKNH@52604|Pleurocapsales 1117|Cyanobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 DYD1_k127_2330299_2 926569.ANT_30480 1.243e-33 138.0 COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF541) - - - ko:K09807 - - - - ko00000 - - - SIMPL DYD1_k127_2330299_3 402881.Plav_2321 4.232e-26 119.0 COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,1JP41@119043|Rhodobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF541) omp28 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K09807 - - - - ko00000 - - - SIMPL DYD1_k127_2330299_4 1128421.JAGA01000003_gene3395 7.712e-15 75.0 COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria 2|Bacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 DYD1_k127_2336908_0 1320556.AVBP01000010_gene3209 8.753e-175 554.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria,43IIH@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 DYD1_k127_2336908_1 1410620.SHLA_27c000460 1.415e-86 296.0 COG2421@1|root,COG2421@2|Bacteria,1MXKY@1224|Proteobacteria,2TSVA@28211|Alphaproteobacteria,4B72J@82115|Rhizobiaceae 28211|Alphaproteobacteria C Acetamidase/Formamidase family - - 3.5.1.4,3.5.1.49 ko:K01426,ko:K01455 ko00330,ko00360,ko00380,ko00460,ko00627,ko00630,ko00643,ko00910,ko01120,ko01200,map00330,map00360,map00380,map00460,map00627,map00630,map00643,map00910,map01120,map01200 - R00524,R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025,RC02432,RC02810 ko00000,ko00001,ko01000 - - - FmdA_AmdA DYD1_k127_2355929_3 196162.Noca_2590 1.237e-19 91.0 COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4DU8X@85009|Propionibacteriales 201174|Actinobacteria M Choline/ethanolamine kinase - - - - - - - - - - - - APH,Choline_kinase DYD1_k127_2355929_1 266117.Rxyl_0773 6.817e-61 231.0 COG0531@1|root,COG0531@2|Bacteria,2IPSH@201174|Actinobacteria,4CQHF@84995|Rubrobacteria 84995|Rubrobacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 DYD1_k127_2355929_0 1382306.JNIM01000001_gene2131 1.449e-79 280.0 COG2129@1|root,COG2129@2|Bacteria,2G7X0@200795|Chloroflexi 200795|Chloroflexi S metallophosphoesterase - - - - - - - - - - - - - DYD1_k127_2355929_2 930171.Asphe3_02290 2.813e-31 127.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,1W7IX@1268|Micrococcaceae 201174|Actinobacteria E Belongs to the GcvT family - - - - - - - - - - - - DAO,FAO_M,GCV_T,GCV_T_C DYD1_k127_2373357_9 1047013.AQSP01000122_gene2227 1.89e-26 116.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - ko:K02282,ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - GerE,Response_reg,TauD DYD1_k127_2373357_11 882086.SacxiDRAFT_3829 4.124e-19 97.0 COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4DX6I@85010|Pseudonocardiales 201174|Actinobacteria K luxR family - - - - - - - - - - - - GerE,Response_reg DYD1_k127_2373357_10 710696.Intca_1882 4.915e-23 109.0 COG2197@1|root,COG2197@2|Bacteria,2IH77@201174|Actinobacteria,4FIEN@85021|Intrasporangiaceae 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_2373357_7 321327.CYA_0005 1.296e-41 168.0 COG0300@1|root,COG0300@2|Bacteria,1G2GZ@1117|Cyanobacteria,1H45Y@1129|Synechococcus 1117|Cyanobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD1_k127_2373357_13 309801.trd_A0181 2.114e-15 87.0 COG1873@1|root,COG3798@1|root,COG1873@2|Bacteria,COG3798@2|Bacteria 2|Bacteria O Protein conserved in bacteria MA20_37705 - - ko:K03886 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002,ko01000 - - - CBS,DUF2171,MgtE_N,PRC DYD1_k127_2373357_8 930171.Asphe3_31150 2.784e-36 141.0 COG1145@1|root,32SB1@2|Bacteria,2IJFQ@201174|Actinobacteria,1W9BP@1268|Micrococcaceae 201174|Actinobacteria C Ferredoxin - - - - - - - - - - - - DUF326 DYD1_k127_2373357_12 745776.DGo_CA0645 1.275e-16 87.0 COG1145@1|root,32SB1@2|Bacteria,1WN0M@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Ferredoxin - - - - - - - - - - - - DUF326 DYD1_k127_2373357_0 926569.ANT_11030 0.0 1139.0 COG1449@1|root,COG4945@1|root,COG1449@2|Bacteria,COG4945@2|Bacteria 2|Bacteria G C-terminal binding-module, SLH-like, of glucodextranase - - - - - - - - - - - - AMPK1_CBM,Glucodextran_C,Glyco_hydro_57 DYD1_k127_2373357_3 316274.Haur_3868 7.75e-161 531.0 COG0366@1|root,COG0366@2|Bacteria,2GB3R@200795|Chloroflexi,3750S@32061|Chloroflexia 32061|Chloroflexia G SMART alpha amylase, catalytic sub domain - - - - - - - - - - - - Alpha-amylase DYD1_k127_2373357_5 1307761.L21SP2_2489 1.906e-120 396.0 COG3833@1|root,COG3833@2|Bacteria,2J6AB@203691|Spirochaetes 203691|Spirochaetes G PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 DYD1_k127_2373357_4 665571.STHERM_c10170 6.899e-125 409.0 COG1175@1|root,COG1175@2|Bacteria,2J6CI@203691|Spirochaetes 203691|Spirochaetes G PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 DYD1_k127_2373357_2 665571.STHERM_c10160 1.654e-161 519.0 COG2182@1|root,COG2182@2|Bacteria,2J5S3@203691|Spirochaetes 203691|Spirochaetes G PFAM Bacterial extracellular solute-binding protein - - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_8 DYD1_k127_2373357_1 926569.ANT_20720 4.14e-167 531.0 COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi 200795|Chloroflexi P PFAM ABC transporter related - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 DYD1_k127_2373357_6 316274.Haur_4010 4.655e-73 256.0 COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia 32061|Chloroflexia K DNA binding - - - - - - - - - - - - DUF4032 DYD1_k127_2381664_4 309801.trd_0159 1.165e-18 86.0 COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi 200795|Chloroflexi S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 DYD1_k127_2381664_6 903818.KI912268_gene2350 2.146e-05 55.0 arCOG03368@1|root,331XD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2381664_3 382464.ABSI01000011_gene2365 9.254e-20 99.0 COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,46VGQ@74201|Verrucomicrobia 74201|Verrucomicrobia C Cytochrome C oxidase, mono-heme subunit/FixO - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO DYD1_k127_2381664_0 269797.Mbar_A1599 5.913e-95 324.0 COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota,2N92Q@224756|Methanomicrobia 224756|Methanomicrobia C Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit hdrD GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 ko:K08264 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 - R04540 RC00011 ko00000,ko00001,ko01000 - - - CCG,Fer4_8 DYD1_k127_2381664_5 768704.Desmer_2170 1.752e-06 59.0 COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia,260K6@186807|Peptococcaceae 186801|Clostridia C Fe-S oxidoreductase - - - - - - - - - - - - CCG,Fer4_8,Nitrate_red_gam DYD1_k127_2381664_2 1125863.JAFN01000001_gene2793 2.238e-39 164.0 COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Cytochrome c pcmF - - - - - - - - - - - Cytochrom_C DYD1_k127_2381664_1 234267.Acid_3505 1.067e-74 259.0 COG1290@1|root,COG1290@2|Bacteria 2|Bacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - - - - - - - - - - Cytochrom_B_C,Cytochrome_B DYD1_k127_2381697_4 926569.ANT_22650 3.093e-27 123.0 COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi 200795|Chloroflexi T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA DYD1_k127_2381697_1 264732.Moth_0070 9.326e-70 243.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales 186801|Clostridia K Response regulator receiver phoP - - ko:K02483,ko:K07658,ko:K07668 ko02020,map02020 M00434,M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_2381697_2 1125863.JAFN01000001_gene1797 2.452e-35 138.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria 28221|Deltaproteobacteria J PFAM Endoribonuclease L-PSP - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP DYD1_k127_2381697_3 1396141.BATP01000007_gene5544 8.087e-30 123.0 2E3V1@1|root,32YSA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2381697_0 926569.ANT_10660 0.0 1247.0 COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi 200795|Chloroflexi J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 DYD1_k127_2381697_6 1206731.BAGB01000063_gene7449 0.0001409 46.0 COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4FXR2@85025|Nocardiaceae 201174|Actinobacteria L (ABC) transporter - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom DYD1_k127_2381697_7 649349.Lbys_1926 0.0004867 52.0 2B2WA@1|root,31VGV@2|Bacteria,4NRR4@976|Bacteroidetes,47QEK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_2386922_1 926569.ANT_30500 6.844e-120 395.0 COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase, family 51 - - - - - - - - - - - - Transgly,Transpeptidase DYD1_k127_2386922_2 926569.ANT_25740 1.445e-107 376.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - - DYD1_k127_2386922_9 926550.CLDAP_04620 6.167e-27 124.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain CP_0155 - - ko:K12204 - - - - ko00000,ko02044 3.A.7.10.1,3.A.7.9.1 - - LysM,T4SS_TraI DYD1_k127_2386922_4 309801.trd_1459 1.47e-99 337.0 COG0624@1|root,COG0624@2|Bacteria,2G60R@200795|Chloroflexi,27Y02@189775|Thermomicrobia 189775|Thermomicrobia E peptidase dimerisation domain protein - - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD1_k127_2386922_5 926569.ANT_30540 2.767e-87 303.0 2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_2386922_0 926569.ANT_08530 4.146e-129 420.0 COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi 200795|Chloroflexi M NAD(P)H-binding - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD1_k127_2386922_6 926569.ANT_08510 1.663e-53 196.0 COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi 200795|Chloroflexi L Belongs to the DNA glycosylase MPG family - - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco DYD1_k127_2386922_3 383372.Rcas_3406 9.447e-102 337.0 COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi,375AJ@32061|Chloroflexia 32061|Chloroflexia I Enoyl- acyl-carrier-protein reductase NADH - - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_2386922_8 1458275.AZ34_13670 8.251e-33 145.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WGYZ@28216|Betaproteobacteria,4AK44@80864|Comamonadaceae 28216|Betaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,SBP_bac_3 DYD1_k127_2386922_7 1123371.ATXH01000010_gene700 1.345e-45 170.0 COG0432@1|root,COG0432@2|Bacteria,2GIHV@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 DYD1_k127_2386922_10 926569.ANT_14070 1.122e-07 54.0 COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi 200795|Chloroflexi S PFAM LmbE family protein - - 3.5.1.115 ko:K18455 - - - - ko00000,ko01000 - - - PIG-L DYD1_k127_2393111_2 1304865.JAGF01000001_gene1459 5.45e-83 284.0 COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria 201174|Actinobacteria G ABC transporter (Permease) - - - - - - - - - - - - BPD_transp_1 DYD1_k127_2393111_3 416591.Tlet_1227 7.785e-80 276.0 COG1175@1|root,COG1175@2|Bacteria 2|Bacteria P transmembrane transport - - - ko:K02025,ko:K05814,ko:K10109,ko:K10118,ko:K15771,ko:K17242,ko:K17245 ko02010,map02010 M00194,M00196,M00198,M00207,M00491,M00600,M00601 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22,3.A.1.1.28,3.A.1.1.3,3.A.1.1.39,3.A.1.1.40 - - BPD_transp_1 DYD1_k127_2393111_1 1304865.JAGF01000001_gene1457 2.643e-87 304.0 COG2182@1|root,COG2182@2|Bacteria,2I2J8@201174|Actinobacteria 201174|Actinobacteria G Extracellular solute-binding protein malE - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_1,SBP_bac_8 DYD1_k127_2393111_0 479435.Kfla_4053 2.088e-97 332.0 COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4DPVT@85009|Propionibacteriales 201174|Actinobacteria GK ROK family - - - - - - - - - - - - HTH_24,MarR_2,ROK DYD1_k127_2393111_4 357808.RoseRS_1504 1.088e-28 119.0 COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia 32061|Chloroflexia C Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct DYD1_k127_2420762_8 926569.ANT_08450 9.089e-154 503.0 COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi 200795|Chloroflexi M Belongs to the DegT DnrJ EryC1 family - - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 DYD1_k127_2420762_26 1173020.Cha6605_4745 3.331e-39 155.0 COG1011@1|root,COG1011@2|Bacteria,1GAP5@1117|Cyanobacteria 1117|Cyanobacteria S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E - - 3.1.3.5 ko:K07025,ko:K08723 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 DYD1_k127_2420762_23 515635.Dtur_0588 2.527e-62 232.0 COG2232@1|root,COG2232@2|Bacteria 2|Bacteria V ATP-grasp domain - - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_3,Epimerase,HAD_2 DYD1_k127_2420762_29 1340493.JNIF01000003_gene4068 1.394e-19 101.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 DYD1_k127_2420762_11 926569.ANT_01770 1.859e-144 470.0 COG0438@1|root,COG0438@2|Bacteria,2G6KX@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 DYD1_k127_2420762_16 1128421.JAGA01000004_gene2684 5.368e-84 284.0 COG2148@1|root,COG2148@2|Bacteria,2NPJQ@2323|unclassified Bacteria 2|Bacteria M Bacterial sugar transferase epsL - - ko:K19428 - - - - ko00000,ko01000 - - - Bac_transf DYD1_k127_2420762_13 926569.ANT_01740 1.066e-101 364.0 COG5360@1|root,COG5360@2|Bacteria 2|Bacteria S Heparinase II/III-like protein - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N DYD1_k127_2420762_1 926569.ANT_30270 4.552e-243 771.0 COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,2G75J@200795|Chloroflexi 200795|Chloroflexi C PFAM Alcohol dehydrogenase zinc-binding domain protein - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD1_k127_2420762_24 243233.MCA0837 3.613e-59 217.0 COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,1S7RK@1236|Gammaproteobacteria,1XFWD@135618|Methylococcales 135618|Methylococcales L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp DYD1_k127_2420762_21 926569.ANT_23140 4.219e-79 280.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_2420762_12 926569.ANT_23150 4.174e-105 353.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_2420762_28 1205680.CAKO01000030_gene4970 7.374e-24 113.0 COG2519@1|root,COG2519@2|Bacteria,1R2V1@1224|Proteobacteria,2TZRX@28211|Alphaproteobacteria,2JZ5N@204441|Rhodospirillales 204441|Rhodospirillales J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 DYD1_k127_2420762_20 926569.ANT_02410 2.531e-80 282.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups pelF - - ko:K21011,ko:K21012 ko02025,map02025 - - - ko00000,ko00001,ko01003 - GT4 - DUF3492,Glyco_trans_1_4,Glycos_transf_1 DYD1_k127_2420762_9 926569.ANT_02400 5.222e-151 487.0 COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi 200795|Chloroflexi M Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 DYD1_k127_2420762_6 926569.ANT_02390 3.4e-175 559.0 COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi 200795|Chloroflexi M PFAM UDP-glucose GDP-mannose dehydrogenase - - 1.1.1.336 ko:K02472 ko00520,ko05111,map00520,map05111 - R03317 RC00291 ko00000,ko00001,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_2420762_25 1227487.C474_05060 2.339e-51 197.0 COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria 2157|Archaea S Serine threonine phosphatase - - - - - - - - - - - - Metallophos DYD1_k127_2420762_14 552811.Dehly_0569 1.564e-89 321.0 COG3568@1|root,COG3568@2|Bacteria,2G7ER@200795|Chloroflexi,34CM1@301297|Dehalococcoidia 301297|Dehalococcoidia S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos DYD1_k127_2420762_18 644966.Tmar_0517 1.019e-81 282.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,25F0C@186801|Clostridia,3WD52@538999|Clostridiales incertae sedis 186801|Clostridia CH PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - 1.1.1.26,1.1.1.310,1.1.1.399,1.1.1.95 ko:K00015,ko:K00058,ko:K16843 ko00260,ko00270,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020 R00717,R01388,R01513,R05693 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT DYD1_k127_2420762_5 1128421.JAGA01000001_gene2444 1.027e-181 583.0 COG2317@1|root,COG2317@2|Bacteria,2NQC7@2323|unclassified Bacteria 2|Bacteria E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues ypwA - 3.4.17.19 ko:K01299,ko:K03281 - - - - ko00000,ko01000,ko01002 2.A.49 - - Peptidase_M32 DYD1_k127_2420762_31 926550.CLDAP_28670 2.549e-14 78.0 2EM6G@1|root,33EVQ@2|Bacteria,2G9RV@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_2420762_30 1121918.ARWE01000001_gene200 1.468e-16 83.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_9 DYD1_k127_2420762_10 65093.PCC7418_1745 8.445e-145 472.0 COG0473@1|root,COG0473@2|Bacteria,1G28W@1117|Cyanobacteria 1117|Cyanobacteria C Isocitrate isopropylmalate dehydrogenase - - - - - - - - - - - - Iso_dh DYD1_k127_2420762_32 926569.ANT_06090 1.148e-13 83.0 COG3266@1|root,COG3266@2|Bacteria 2|Bacteria GM domain, Protein - - - - - - - - - - - - FG-GAP_2,WXG100 DYD1_k127_2420762_4 926569.ANT_06210 2.067e-185 598.0 COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi 200795|Chloroflexi V PFAM VanW family protein - - - - - - - - - - - - G5,PG_binding_4,VanW DYD1_k127_2420762_27 926569.ANT_06190 1.401e-25 107.0 COG2835@1|root,COG2835@2|Bacteria 2|Bacteria EG tetraacyldisaccharide 4'-kinase activity - - - ko:K09791 - - - - ko00000 - - - Methyltransf_11,Methyltransf_25,Trm112p DYD1_k127_2420762_38 1173028.ANKO01000214_gene6277 0.0004094 51.0 COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales 1117|Cyanobacteria C PBS lyase HEAT-like repeat - - - - - - - - - - - - HEAT_2,HEAT_PBS DYD1_k127_2420762_33 222534.KB893705_gene5841 2.376e-11 76.0 COG2839@1|root,COG2839@2|Bacteria,2IQDE@201174|Actinobacteria,4EW98@85013|Frankiales 201174|Actinobacteria S Protein of unknown function (DUF456) - - - ko:K09793 - - - - ko00000 - - - DUF456 DYD1_k127_2420762_3 926569.ANT_23610 2.006e-186 591.0 COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b DYD1_k127_2420762_36 1123320.KB889704_gene9379 3.576e-05 52.0 COG1846@1|root,COG1846@2|Bacteria,2GQK4@201174|Actinobacteria 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 DYD1_k127_2420762_7 309799.DICTH_0538 5.318e-164 535.0 COG0156@1|root,COG0156@2|Bacteria 2|Bacteria E 8-amino-7-oxononanoate synthase activity bioF GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_2420762_19 875328.JDM601_0482 2.399e-81 282.0 COG0451@1|root,COG0451@2|Bacteria,2GN90@201174|Actinobacteria,23871@1762|Mycobacteriaceae 201174|Actinobacteria M Polysaccharide biosynthesis protein - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase DYD1_k127_2420762_2 765420.OSCT_3114 2.348e-238 753.0 COG1132@1|root,COG1132@2|Bacteria,2G7QD@200795|Chloroflexi,376IN@32061|Chloroflexia 32061|Chloroflexia P PFAM ABC transporter related - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_2420762_0 665571.STHERM_c16630 0.0 1540.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,2J5QV@203691|Spirochaetes 203691|Spirochaetes C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin nifJ - 1.2.7.1 ko:K00169,ko:K03737 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C DYD1_k127_2420762_15 1122247.C731_4072 7.032e-89 305.0 COG1575@1|root,COG1575@2|Bacteria,2IPQ8@201174|Actinobacteria,23E29@1762|Mycobacteriaceae 201174|Actinobacteria H Belongs to the MenA family. Type 1 subfamily - - - - - - - - - - - - UbiA DYD1_k127_2420762_22 926569.ANT_04960 6.47e-69 248.0 COG0451@1|root,COG0451@2|Bacteria,2G8UC@200795|Chloroflexi 200795|Chloroflexi M NmrA-like family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase DYD1_k127_2420762_17 926569.ANT_31200 4.848e-83 310.0 COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA DYD1_k127_243245_1 383372.Rcas_3466 2.637e-77 265.0 COG0548@1|root,COG0548@2|Bacteria,2G5WV@200795|Chloroflexi,375DI@32061|Chloroflexia 32061|Chloroflexia E Belongs to the acetylglutamate kinase family. LysZ subfamily lysZ - - ko:K05828 ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230 M00031,M00763 R09776,R10930 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD1_k127_243245_0 324602.Caur_0335 4.595e-139 452.0 COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi,374YZ@32061|Chloroflexia 32061|Chloroflexia E Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde lysY - - ko:K05829 ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230 M00031,M00763 R09777,R10931 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh DYD1_k127_2442826_9 1303518.CCALI_01253 9.96e-45 174.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - - - - - - - - - - AhpC-TSA,Redoxin,Thioredoxin DYD1_k127_2442826_7 926569.ANT_07860 5.936e-76 266.0 COG1316@1|root,COG1316@2|Bacteria 2|Bacteria K TRANSCRIPTIONal - - - - - - - - - - - - LytR_C,LytR_cpsA_psr DYD1_k127_2442826_16 383372.Rcas_0534 0.0009344 46.0 COG3170@1|root,COG3170@2|Bacteria,2GBRC@200795|Chloroflexi,375MT@32061|Chloroflexia 32061|Chloroflexia NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - - DYD1_k127_2442826_10 926569.ANT_16430 2.064e-41 163.0 COG0745@1|root,COG0745@2|Bacteria 926569.ANT_16430|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_2442826_12 926569.ANT_16420 3.624e-21 100.0 COG1430@1|root,COG1430@2|Bacteria 2|Bacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 DYD1_k127_2442826_4 926569.ANT_16410 3.984e-93 325.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi 200795|Chloroflexi M Lysin motif - - - - - - - - - - - - LysM,Peptidase_M23 DYD1_k127_2442826_2 926569.ANT_16400 6.077e-143 470.0 2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_2442826_11 926569.ANT_16390 1.553e-34 141.0 2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_2442826_13 1345023.M467_00830 2.316e-08 64.0 2BIVC@1|root,32D3E@2|Bacteria,1VN3B@1239|Firmicutes,4I7VC@91061|Bacilli,3WFSW@539002|Bacillales incertae sedis 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_2442826_5 926569.ANT_20410 1.096e-89 301.0 COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi 200795|Chloroflexi K Two component transcriptional regulator, winged helix family - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_2442826_6 926569.ANT_20400 1.276e-82 293.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2GBIC@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - 2.7.13.3 ko:K02484,ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_2442826_0 479434.Sthe_0796 6.914e-288 898.0 COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia 189775|Thermomicrobia L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB DYD1_k127_2442826_3 926569.ANT_11320 1.295e-105 358.0 COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi 200795|Chloroflexi S SMART phosphoesterase PHP domain protein - - - - - - - - - - - - - DYD1_k127_2442826_15 1203622.HMPREF1290_01084 0.0005841 49.0 COG2340@1|root,COG2340@2|Bacteria 2|Bacteria S peptidase inhibitor activity - - - - - - - - - - - - CAP,CarboxypepD_reg,HemolysinCabind DYD1_k127_2442826_1 926569.ANT_25540 2.182e-177 575.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi 200795|Chloroflexi L PHP domain protein - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_thumb,HHH_5,HHH_8,PHP DYD1_k127_2442826_8 926569.ANT_22980 2.399e-74 262.0 COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi 200795|Chloroflexi S PFAM DegV family protein - - - - - - - - - - - - DegV DYD1_k127_2464627_8 926569.ANT_08190 6.088e-28 115.0 COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi 200795|Chloroflexi K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD1_k127_2464627_5 562970.Btus_1924 1.017e-63 232.0 COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4I2KV@91061|Bacilli,278R7@186823|Alicyclobacillaceae 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_2464627_4 316274.Haur_3061 1.333e-69 242.0 COG0745@1|root,COG0745@2|Bacteria,2GAJP@200795|Chloroflexi,37683@32061|Chloroflexia 32061|Chloroflexia K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C DYD1_k127_2464627_2 1122138.AQUZ01000041_gene7242 4.443e-78 271.0 COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4DUY3@85009|Propionibacteriales 201174|Actinobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C DYD1_k127_2464627_3 63737.Npun_R0619 3.518e-71 249.0 COG1028@1|root,COG1028@2|Bacteria,1G7G6@1117|Cyanobacteria,1HQIB@1161|Nostocales 1117|Cyanobacteria C Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_2464627_10 706587.Desti_4721 1.163e-24 108.0 2DZFA@1|root,32V98@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2464627_1 706587.Desti_4719 7.54e-132 434.0 COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales 28221|Deltaproteobacteria D Anion-transporting ATPase arsA - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase DYD1_k127_2464627_0 706587.Desti_4720 1.982e-136 441.0 COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales 28221|Deltaproteobacteria D Anion-transporting ATPase arsA - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase DYD1_k127_2464627_7 706587.Desti_4721 3.211e-35 141.0 2DZFA@1|root,32V98@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2464627_9 706587.Desti_4721 3.93e-25 109.0 2DZFA@1|root,32V98@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2464627_11 1128421.JAGA01000003_gene3244 2.118e-11 74.0 2EMGM@1|root,33F5A@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2464627_6 706587.Desti_4722 8.294e-61 227.0 COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria 28221|Deltaproteobacteria T carbon starvation protein CstA cstA - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM DYD1_k127_2475270_13 944480.ATUV01000002_gene127 1.738e-05 55.0 COG2142@1|root,COG2142@2|Bacteria,1Q5Y0@1224|Proteobacteria,4321V@68525|delta/epsilon subdivisions,2WX4X@28221|Deltaproteobacteria,2M79B@213113|Desulfurellales 28221|Deltaproteobacteria C Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt DYD1_k127_2475270_12 290512.Paes_2257 1.723e-14 79.0 COG2009@1|root,COG2009@2|Bacteria,1FE6C@1090|Chlorobi 1090|Chlorobi C TIGRFAM succinate dehydrogenase, cytochrome b556 subunit - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt DYD1_k127_2475270_8 292459.STH2640 6.687e-66 233.0 COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia 186801|Clostridia C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 DYD1_k127_2475270_1 306281.AJLK01000020_gene2966 6.034e-177 574.0 COG1053@1|root,COG1053@2|Bacteria,1G2KV@1117|Cyanobacteria,1JGTJ@1189|Stigonemataceae 1117|Cyanobacteria C Fumarate reductase flavoprotein C-term sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_2475270_3 383372.Rcas_4277 4.781e-142 473.0 COG0304@1|root,COG0304@2|Bacteria,2G7RK@200795|Chloroflexi,376IR@32061|Chloroflexia 32061|Chloroflexia IQ Belongs to the beta-ketoacyl-ACP synthases family - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_2475270_11 234621.RER_21420 3.861e-17 85.0 COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4FX6C@85025|Nocardiaceae 201174|Actinobacteria K response regulator tcsR2 - - - - - - - - - - - GerE,Response_reg DYD1_k127_2475270_4 926569.ANT_24720 2.57e-135 452.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi 200795|Chloroflexi T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,GAF_3,HATPase_c,HisKA_3 DYD1_k127_2475270_0 926569.ANT_28820 2.804e-180 574.0 COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi 200795|Chloroflexi C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88 ko:K00054 ko00900,ko01110,ko01130,map00900,map01110,map01130 - R02081 RC00004,RC00644 ko00000,ko00001,ko01000 - - - HMG-CoA_red DYD1_k127_2475270_2 926569.ANT_28810 2.497e-167 533.0 COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi 200795|Chloroflexi I 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein - - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - ACP_syn_III_C DYD1_k127_2475270_5 926569.ANT_28800 1.795e-108 363.0 COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi 200795|Chloroflexi I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD1_k127_2475270_9 926569.ANT_28790 3.955e-61 213.0 COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi 200795|Chloroflexi S DUF35 OB-fold domain, acyl-CoA-associated - - - ko:K07068 - - - - ko00000 - - - DUF35_N,OB_aCoA_assoc DYD1_k127_2475270_6 1157943.KB892705_gene965 2.122e-94 325.0 COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,234R8@1762|Mycobacteriaceae 201174|Actinobacteria IK Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Trans_reg_C DYD1_k127_2475270_10 485913.Krac_10670 2.714e-18 98.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulator, LuxR family - - - - - - - - - - - - AAA_22,GerE,NB-ARC,TPR_12 DYD1_k127_2475270_7 926560.KE387027_gene707 4.714e-82 280.0 COG1765@1|root,COG1765@2|Bacteria,1WM1H@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O OsmC-like protein - - - - - - - - - - - - OsmC DYD1_k127_2481193_2 1122603.ATVI01000005_gene3500 0.0004793 45.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales 135614|Xanthomonadales T Adenylate cyclase - - - - - - - - - - - - TPR_8 DYD1_k127_2481193_0 1121918.ARWE01000001_gene10 5.658e-91 310.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria 28221|Deltaproteobacteria L transposase IS116 IS110 IS902 family protein - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 DYD1_k127_2481193_1 1121382.JQKG01000019_gene1276 3.761e-32 138.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - ko:K06889 - - - - ko00000 - - - BAAT_C,Hydrolase_4,Peptidase_S9 DYD1_k127_2489342_8 266117.Rxyl_1010 6.492e-25 109.0 COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4CQKQ@84995|Rubrobacteria 84995|Rubrobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_2489342_9 338963.Pcar_2064 4.878e-15 79.0 COG2261@1|root,COG2261@2|Bacteria,1NE11@1224|Proteobacteria 1224|Proteobacteria S transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc DYD1_k127_2489342_10 55952.BU52_16575 4.563e-08 59.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator, arsR - - - - - - - - - - - - HTH_20,HTH_5,Rhodanese DYD1_k127_2489342_0 1121946.AUAX01000021_gene8088 3.403e-96 328.0 COG0473@1|root,COG0473@2|Bacteria,2I8V7@201174|Actinobacteria 201174|Actinobacteria CE Isocitrate isopropylmalate dehydrogenase - - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD1_k127_2489342_4 1210884.HG799465_gene11339 1.509e-57 205.0 COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes 203682|Planctomycetes H RibD C-terminal domain - - - - - - - - - - - - RibD_C DYD1_k127_2489342_1 1300345.LF41_1458 2.484e-80 283.0 COG2309@1|root,COG2309@2|Bacteria 2|Bacteria E aminopeptidase activity - - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - HTH_20,Peptidase_M29 DYD1_k127_2489342_7 1210046.B277_13484 2.065e-27 126.0 COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria,4FFH8@85021|Intrasporangiaceae 201174|Actinobacteria E COG1748 Saccharopine dehydrogenase and related lys1 - 1.5.1.7 ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715 RC00217,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP DYD1_k127_2489342_5 243233.MCA1906 1.51e-45 172.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RZFF@1236|Gammaproteobacteria,1XF0J@135618|Methylococcales 135618|Methylococcales C Di-haem cytochrome c peroxidase - - - - - - - - - - - - CCP_MauG,Cytochrom_C DYD1_k127_2489342_2 1472716.KBK24_0124815 2.661e-74 259.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,1K08S@119060|Burkholderiaceae 28216|Betaproteobacteria P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin DYD1_k127_2489342_6 903818.KI912268_gene3050 1.936e-32 130.0 COG0735@1|root,COG0735@2|Bacteria,3Y7UH@57723|Acidobacteria 57723|Acidobacteria P Ferric uptake regulator family - - - ko:K09825 - - - - ko00000,ko03000 - - - FUR DYD1_k127_2489342_3 1123073.KB899244_gene260 2.288e-60 218.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X5CT@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran DYD1_k127_2489451_4 1380390.JIAT01000010_gene3534 9.113e-64 231.0 COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria 84995|Rubrobacteria M Choline/ethanolamine kinase - - - - - - - - - - - - Choline_kinase DYD1_k127_2489451_0 1380390.JIAT01000010_gene3535 4.536e-281 887.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4CPSG@84995|Rubrobacteria 84995|Rubrobacteria E FAD dependent oxidoreductase central domain - - - - - - - - - - - - DAO,FAO_M,GCV_T,GCV_T_C DYD1_k127_2489451_6 1259795.ARJK01000003_gene904 2.566e-49 181.0 2F35P@1|root,33W0B@2|Bacteria,1VVSQ@1239|Firmicutes,251EN@186801|Clostridia,42ICJ@68295|Thermoanaerobacterales 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_2489451_3 1499967.BAYZ01000117_gene3320 2.079e-117 384.0 COG0637@1|root,COG0637@2|Bacteria 2|Bacteria S phosphonoacetaldehyde hydrolase activity cbbY - - - - - - - - - - - HAD_2 DYD1_k127_2489451_1 1499967.BAYZ01000117_gene3321 2.718e-161 515.0 COG0079@1|root,COG0079@2|Bacteria,2NNZK@2323|unclassified Bacteria 2|Bacteria E Aminotransferase class I and II hisD - 1.1.1.23,2.6.1.9 ko:K00013,ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R01158,R01163,R03012,R03243 RC00006,RC00099,RC00242,RC00463,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2,Histidinol_dh DYD1_k127_2489451_2 1499967.BAYZ01000117_gene3322 1.752e-144 468.0 COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria 2|Bacteria G Fructose-bisphosphate aldolase class-II fba2 - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase,PHP DYD1_k127_2489451_7 420246.GTNG_2203 2.246e-32 136.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1WEZR@129337|Geobacillus 91061|Bacilli K UTRA yvoA - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA DYD1_k127_2489451_5 518766.Rmar_0497 1.355e-62 231.0 COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1FKD5@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD1_k127_2494359_3 945713.IALB_0894 2.049e-09 64.0 COG1005@1|root,COG1005@2|Bacteria 2|Bacteria C quinone binding nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_2494359_0 926569.ANT_24790 1.917e-172 568.0 COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi 200795|Chloroflexi C Molydopterin dinucleotide binding domain - - - - - - - - - - - - Molybdopterin,Molydop_binding DYD1_k127_2494359_1 926569.ANT_24800 7.078e-43 163.0 COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi 200795|Chloroflexi C Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrome_C7 DYD1_k127_2494359_2 1382306.JNIM01000001_gene1045 1.03e-37 146.0 COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi 200795|Chloroflexi K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg DYD1_k127_2537330_18 1380408.AVGH01000044_gene1352 5.34e-26 110.0 2DSQW@1|root,33H3S@2|Bacteria,1VP4J@1239|Firmicutes,4HSVH@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_2537330_14 1123504.JQKD01000030_gene4596 2.785e-37 147.0 COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria,2VT4V@28216|Betaproteobacteria,4AFU0@80864|Comamonadaceae 28216|Betaproteobacteria O Ergosterol biosynthesis ERG4/ERG24 family - - - - - - - - - - - - PEMT DYD1_k127_2537330_9 696747.NIES39_E02470 9.305e-55 216.0 COG1807@1|root,COG1807@2|Bacteria,1G0W2@1117|Cyanobacteria,1H9QQ@1150|Oscillatoriales 1117|Cyanobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_2537330_5 1121346.KB899855_gene93 1e-71 248.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,26RVY@186822|Paenibacillaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 DYD1_k127_2537330_21 926569.ANT_01350 4.976e-18 89.0 COG0718@1|root,COG0718@2|Bacteria 2|Bacteria S YbaB/EbfC DNA-binding family ybaB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - ko:K06187,ko:K09747 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - YbaB_DNA_bd DYD1_k127_2537330_1 926569.ANT_01340 2.765e-164 532.0 COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi 200795|Chloroflexi L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 DYD1_k127_2537330_13 1089551.KE386572_gene1955 6.086e-42 173.0 COG3119@1|root,COG3119@2|Bacteria,1MYHH@1224|Proteobacteria,2UA67@28211|Alphaproteobacteria 28211|Alphaproteobacteria P arylsulfatase activity - - - - - - - - - - - - Sulfatase DYD1_k127_2537330_23 485915.Dret_1391 3.087e-11 70.0 2D7FD@1|root,32TNY@2|Bacteria,1NAHU@1224|Proteobacteria,42VAC@68525|delta/epsilon subdivisions,2WR6Q@28221|Deltaproteobacteria,2MCEJ@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM DnaJ homologue, subfamily C, member 28 - - - - - - - - - - - - DUF1992 DYD1_k127_2537330_22 926569.ANT_01330 1.327e-16 89.0 COG2333@1|root,COG2333@2|Bacteria 2|Bacteria N competence protein COMEC ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B DYD1_k127_2537330_4 709986.Deima_1228 4.194e-75 267.0 COG4805@1|root,COG4805@2|Bacteria,1WM4J@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein conserved in bacteria - - - - - - - - - - - - - DYD1_k127_2537330_20 357808.RoseRS_3314 1.762e-19 103.0 COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi,375WR@32061|Chloroflexia 32061|Chloroflexia S YacP-like NYN domain - - - ko:K06962 - - - - ko00000 - - - NYN_YacP DYD1_k127_2537330_15 479434.Sthe_1008 1.251e-29 133.0 COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi 200795|Chloroflexi K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_2537330_16 710696.Intca_3539 1.238e-28 123.0 COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria,4FIIB@85021|Intrasporangiaceae 201174|Actinobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.11 ko:K03428 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R04237 RC00003,RC00460 ko00000,ko00001,ko01000 - - - Methyltransf_11,Methyltransf_25 DYD1_k127_2537330_10 502025.Hoch_5191 3.446e-53 204.0 COG1024@1|root,COG1024@2|Bacteria,1MVJJ@1224|Proteobacteria 1224|Proteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD1_k127_2537330_25 65497.JODV01000007_gene529 5.349e-07 59.0 COG1073@1|root,COG1073@2|Bacteria,2GKYQ@201174|Actinobacteria,4E2DY@85010|Pseudonocardiales 201174|Actinobacteria S Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 DYD1_k127_2537330_19 1123508.JH636441_gene3020 8.331e-20 95.0 291S1@1|root,2ZPBY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2537330_8 1382356.JQMP01000003_gene2180 3.388e-57 208.0 COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,27Y6E@189775|Thermomicrobia 189775|Thermomicrobia K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 DYD1_k127_2537330_3 926569.ANT_25520 3.141e-78 267.0 COG0503@1|root,COG0503@2|Bacteria,2G71F@200795|Chloroflexi 200795|Chloroflexi F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran DYD1_k127_2537330_0 926569.ANT_25510 1.115e-229 721.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G5WB@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase DYD1_k127_2537330_12 926569.ANT_25500 1.547e-43 171.0 2DFV5@1|root,2ZT9W@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2537330_11 926569.ANT_29560 3.933e-52 206.0 COG1716@1|root,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination CP_0034 - - - - - - - - - - - BON,FHA,FTSW_RODA_SPOVE,Yop-YscD_cpl DYD1_k127_2537330_7 926569.ANT_29550 1.716e-61 226.0 COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi 200795|Chloroflexi T SMART protein phosphatase 2C domain protein - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 DYD1_k127_2537330_2 926562.Oweho_2949 1.187e-86 295.0 COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,1HXN8@117743|Flavobacteriia,2PAZB@246874|Cryomorphaceae 976|Bacteroidetes P TIGRFAM cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux DYD1_k127_2537330_6 891968.Anamo_0049 5.986e-62 224.0 COG0697@1|root,COG0697@2|Bacteria,3TB45@508458|Synergistetes 508458|Synergistetes EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_2556635_0 926569.ANT_29800 2.022e-86 291.0 COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 DYD1_k127_2556635_1 926569.ANT_22190 1.457e-40 164.0 COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi 2|Bacteria S Ig-like domain from next to BRCA1 gene - - - - - - - - - - - - DUF11,N_BRCA1_IG DYD1_k127_2576707_2 926569.ANT_04210 2.995e-78 268.0 COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi 200795|Chloroflexi C Proline dehydrogenase - - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh DYD1_k127_2576707_3 926569.ANT_30690 2.436e-51 190.0 COG1028@1|root,COG1028@2|Bacteria,2G8K5@200795|Chloroflexi 200795|Chloroflexi IQ PFAM short-chain dehydrogenase reductase SDR - - 1.1.1.100,1.5.1.33 ko:K00059,ko:K03793 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_2576707_9 401053.AciPR4_2197 0.0004689 51.0 2AYX9@1|root,31R2Z@2|Bacteria,3Y4ZH@57723|Acidobacteria,2JJGK@204432|Acidobacteriia 204432|Acidobacteriia S DinB superfamily - - - - - - - - - - - - DinB_2 DYD1_k127_2576707_5 1521187.JPIM01000111_gene2340 6.265e-29 131.0 COG0382@1|root,COG0382@2|Bacteria 2|Bacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - 2.5.1.39,2.5.1.42,2.5.1.74 ko:K02548,ko:K03179,ko:K17105 ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110 M00116,M00117 R04520,R05000,R05615,R05617,R06858,R10757 RC00209,RC01171,RC02895,RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - Flavodoxin_2,UbiA DYD1_k127_2576707_1 926569.ANT_04230 6.817e-125 412.0 COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi 200795|Chloroflexi H MoeA domain protein domain I and II - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N DYD1_k127_2576707_0 926569.ANT_04250 1.347e-251 794.0 COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi 200795|Chloroflexi K PBP superfamily domain - - 2.10.1.1 ko:K03750,ko:K07219 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - HTH_3,MoCF_biosynth,MoeA_C,MoeA_N,PBP_like DYD1_k127_2576707_6 1210884.HG799474_gene15133 8.056e-24 115.0 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - CHU_C,VCBS DYD1_k127_2576707_8 1449126.JQKL01000025_gene2386 6.65e-06 59.0 COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1V9XU@1239|Firmicutes,24NW6@186801|Clostridia 186801|Clostridia M ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - LysM,YkuD DYD1_k127_2576707_4 1210884.HG799474_gene15133 1.97e-35 153.0 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - CHU_C,VCBS DYD1_k127_2576707_7 1192034.CAP_5133 4.526e-08 54.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,42YEF@68525|delta/epsilon subdivisions,2WU92@28221|Deltaproteobacteria,2YYRX@29|Myxococcales 28221|Deltaproteobacteria E Peptidase family S58 dmpA - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 DYD1_k127_2592307_2 926569.ANT_12080 1.86e-136 452.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM,OapA,OapA_N,Peptidase_M23 DYD1_k127_2592307_4 926569.ANT_12100 2.578e-127 425.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM,OapA,OapA_N,Peptidase_M23 DYD1_k127_2592307_3 926569.ANT_12110 6.047e-135 449.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria 2|Bacteria M LysM domain - - 2.7.7.6 ko:K03046,ko:K03641,ko:K08642 ko00230,ko00240,ko01100,ko02024,ko03020,map00230,map00240,map01100,map02024,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021,ko03400 2.C.1.2 - - Glyco_hydro_18,LysM,OapA,PD40,Peptidase_M23 DYD1_k127_2592307_7 926569.ANT_10630 2.152e-28 122.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_2592307_0 926569.ANT_10620 1.592e-240 771.0 COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi 200795|Chloroflexi H Polynucleotide adenylyltransferase region - - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd DYD1_k127_2592307_1 1128421.JAGA01000003_gene3116 1.328e-140 464.0 COG0366@1|root,COG0366@2|Bacteria,2NP2D@2323|unclassified Bacteria 2|Bacteria G Alpha amylase, catalytic domain - - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,Malt_amylase_C DYD1_k127_2592307_5 926569.ANT_10920 1.904e-77 267.0 COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi 200795|Chloroflexi H PFAM Biotin lipoate A B protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB DYD1_k127_2592307_8 926569.ANT_22500 1.483e-17 88.0 COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF503) - - - ko:K09764 - - - - ko00000 - - - DUF503 DYD1_k127_2592307_6 344747.PM8797T_17999 4.275e-62 230.0 COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes 203682|Planctomycetes T FHA domain - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - FHA,GAF_2,SpoIIE DYD1_k127_2606053_1 926569.ANT_18320 2.725e-22 100.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - ko:K03413,ko:K07719 ko02020,ko02030,map02020,map02030 M00506,M00518 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HATPase_c,Response_reg,YcbB DYD1_k127_2606053_0 479434.Sthe_0827 7.022e-180 587.0 COG0613@1|root,COG2865@1|root,COG0613@2|Bacteria,COG2865@2|Bacteria,2G5UU@200795|Chloroflexi 200795|Chloroflexi K SMART phosphoesterase PHP domain protein - - - - - - - - - - - - AlbA_2,PHP DYD1_k127_2630815_3 398512.JQKC01000002_gene1732 8.311e-10 70.0 2ERNT@1|root,33J87@2|Bacteria,1VMAP@1239|Firmicutes,24X0B@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_2630815_1 926569.ANT_12370 2.233e-120 398.0 COG0624@1|root,COG0624@2|Bacteria,2G61X@200795|Chloroflexi 200795|Chloroflexi E Catalyzes the release of L-lysine from LysW -gamma-L- lysine lysK - - ko:K05831 ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230 M00031,M00763 R09779,R10933 RC00064,RC00090 ko00000,ko00001,ko00002 - - - Peptidase_M20 DYD1_k127_2630815_0 1382306.JNIM01000001_gene569 1.19e-148 480.0 COG0624@1|root,COG4992@1|root,COG0624@2|Bacteria,COG4992@2|Bacteria,2G5SG@200795|Chloroflexi 200795|Chloroflexi E Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine lysJ - - ko:K05830 ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230 M00031,M00763 R09778,R10932 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3,Peptidase_M20 DYD1_k127_2630815_2 383372.Rcas_3466 7.301e-22 96.0 COG0548@1|root,COG0548@2|Bacteria,2G5WV@200795|Chloroflexi,375DI@32061|Chloroflexia 32061|Chloroflexia E Belongs to the acetylglutamate kinase family. LysZ subfamily lysZ - - ko:K05828 ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230 M00031,M00763 R09776,R10930 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD1_k127_2632049_0 926569.ANT_12990 6.222e-133 440.0 COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi 200795|Chloroflexi V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 DYD1_k127_2632049_1 1128421.JAGA01000002_gene906 2.74e-27 117.0 COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria 2|Bacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 DYD1_k127_2633294_5 926550.CLDAP_22340 6.054e-195 624.0 COG1132@1|root,COG1132@2|Bacteria,2G5RP@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_2633294_43 1480694.DC28_07535 8.347e-13 74.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - MarR,MarR_2 DYD1_k127_2633294_17 926569.ANT_06180 3.811e-102 344.0 COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - - - - - - - - - - LytR_C,LytR_cpsA_psr DYD1_k127_2633294_31 926569.ANT_03890 2.208e-35 156.0 COG0457@1|root,COG0457@2|Bacteria 926569.ANT_03890|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_2633294_45 1297865.APJD01000007_gene1919 7.652e-10 67.0 COG4278@1|root,COG4278@2|Bacteria,1RBTS@1224|Proteobacteria,2U33M@28211|Alphaproteobacteria,3JWV5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H phenylacetate-CoA ligase activity - - - - - - - - - - - - - DYD1_k127_2633294_34 1202962.KB907168_gene2246 2.447e-21 102.0 COG3714@1|root,COG3714@2|Bacteria,1PN0I@1224|Proteobacteria,1RNUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane yhhN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - YhhN DYD1_k127_2633294_8 1191523.MROS_1373 1.753e-155 500.0 COG0436@1|root,COG0436@2|Bacteria 2|Bacteria E Aminotransferase - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_2633294_1 945713.IALB_1079 6.838e-233 744.0 COG1866@1|root,COG1866@2|Bacteria 2|Bacteria H phosphoenolpyruvate carboxykinase (ATP) activity pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP DYD1_k127_2633294_27 926569.ANT_17320 2.939e-54 203.0 29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_2633294_12 243233.MCA2776 5.611e-125 421.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales 135618|Methylococcales C Apoptosis-inducing factor, mitochondrion-associated, C-term - - - - - - - - - - - - AIF_C,Pyr_redox_2 DYD1_k127_2633294_21 926569.ANT_28960 1.708e-80 278.0 COG1814@1|root,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi 200795|Chloroflexi S VIT family - - - - - - - - - - - - VIT1 DYD1_k127_2633294_0 926569.ANT_16290 6.826e-314 972.0 COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi 200795|Chloroflexi F Belongs to the formate--tetrahydrofolate ligase family fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 ko:K00288,ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00141,M00377 R00943,R01220,R01655 RC00026,RC00111,RC00202,RC00578 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FTHFS DYD1_k127_2633294_10 886293.Sinac_1438 1.49e-136 447.0 COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes 203682|Planctomycetes G phosphoglycerate mutase - - 5.4.2.12 ko:K15635 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,PhosphMutase DYD1_k127_2633294_11 926569.ANT_13260 2.233e-128 426.0 COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi 200795|Chloroflexi S Required for morphogenesis under gluconeogenic growth conditions - - - - - - - - - - - - UPF0052 DYD1_k127_2633294_9 997346.HMPREF9374_2226 5.465e-137 446.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,27BBG@186824|Thermoactinomycetaceae 91061|Bacilli G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD1_k127_2633294_6 926550.CLDAP_03690 3.03e-161 516.0 COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi 200795|Chloroflexi F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK DYD1_k127_2633294_24 266940.Krad_0072 7.844e-68 252.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria 201174|Actinobacteria KLT serine threonine protein kinase pknB GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase DYD1_k127_2633294_19 926569.ANT_19840 4.365e-89 324.0 COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase DYD1_k127_2633294_16 1128421.JAGA01000001_gene2038 2.505e-108 379.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria 2|Bacteria KT COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - GAF,GAF_2,GGDEF,SpoIIE DYD1_k127_2633294_44 368407.Memar_2469 1.129e-11 73.0 COG2172@1|root,arCOG06892@2157|Archaea,2Y5NU@28890|Euryarchaeota 28890|Euryarchaeota T Histidine kinase-like ATPase domain - - - - - - - - - - - - HATPase_c_2 DYD1_k127_2633294_42 1121385.AQXW01000004_gene2322 7.625e-13 72.0 COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria,1ZWXY@145357|Dermacoccaceae 201174|Actinobacteria T Belongs to the anti-sigma-factor antagonist family rsbV GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04749 - - - - ko00000,ko03021 - - - STAS DYD1_k127_2633294_20 926569.ANT_14700 7.131e-85 294.0 COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi 200795|Chloroflexi H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30,2.5.1.90 ko:K00805,ko:K02523 ko00900,ko01110,map00900,map01110 - R09247,R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt DYD1_k127_2633294_23 521098.Aaci_0129 2.468e-69 251.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,27859@186823|Alicyclobacillaceae 91061|Bacilli L TatD related DNase tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase DYD1_k127_2633294_4 926569.ANT_14720 5.752e-198 630.0 COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi 200795|Chloroflexi G phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_2633294_37 926569.ANT_22410 2.095e-20 95.0 COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi 200795|Chloroflexi J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 DYD1_k127_2633294_25 926569.ANT_22420 7.034e-58 204.0 COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi 200795|Chloroflexi L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB DYD1_k127_2633294_35 926569.ANT_22430 2.821e-21 97.0 COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi 200795|Chloroflexi J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 DYD1_k127_2633294_26 926569.ANT_22440 4.118e-57 215.0 COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi 200795|Chloroflexi O PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - - - - - - - - - - Rotamase,Rotamase_3,SurA_N_3 DYD1_k127_2633294_2 525904.Tter_0998 4.345e-220 704.0 COG0317@1|root,COG0317@2|Bacteria,2NNM0@2323|unclassified Bacteria 2|Bacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - iSFV_1184.SFV_2673 ACT_4,HD_4,RelA_SpoT,TGS DYD1_k127_2633294_36 324602.Caur_0293 4.009e-21 98.0 COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,3764Y@32061|Chloroflexia 32061|Chloroflexia CO PFAM Vitamin K epoxide reductase - - - - - - - - - - - - VKOR DYD1_k127_2633294_30 926550.CLDAP_39600 1.136e-38 160.0 COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi 200795|Chloroflexi J PFAM RNA binding S1 domain protein - - - - - - - - - - - - S1 DYD1_k127_2633294_7 926569.ANT_11300 4.44e-156 510.0 COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi 200795|Chloroflexi E PFAM extracellular solute-binding protein, family 5 - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_2633294_46 525904.Tter_0916 7.937e-07 54.0 COG1314@1|root,COG1314@2|Bacteria,2NS1U@2323|unclassified Bacteria 2|Bacteria U Preprotein translocase SecG subunit secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG DYD1_k127_2633294_13 1382356.JQMP01000004_gene638 1.326e-122 402.0 COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,27XS7@189775|Thermomicrobia 189775|Thermomicrobia J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD1_k127_2633294_33 768671.ThimaDRAFT_1522 5.373e-22 106.0 2DRNI@1|root,33CD9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2633294_39 649638.Trad_1790 1.046e-16 90.0 COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S membrane - - - - - - - - - - - - DUF2154 DYD1_k127_2633294_32 357808.RoseRS_4198 4.389e-31 132.0 2E64T@1|root,330TJ@2|Bacteria,2G93I@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_2633294_38 926560.KE387027_gene895 5.459e-20 95.0 COG1983@1|root,COG1983@2|Bacteria,1WKSH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus KT PspC domain - - - - - - - - - - - - PspC DYD1_k127_2633294_29 926560.KE387027_gene896 1.918e-40 161.0 COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S membrane - - - - - - - - - - - - DUF2154 DYD1_k127_2633294_18 926569.ANT_04000 9.997e-101 336.0 COG3868@1|root,COG3868@2|Bacteria 2|Bacteria S Glycoside-hydrolase family GH114 - - - ko:K21006 ko02025,map02025 - - - ko00000,ko00001 - - - Glyco_hydro_114 DYD1_k127_2633294_22 68219.JNXI01000002_gene3959 5.886e-73 256.0 2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_2633294_3 926569.ANT_09770 1.653e-199 633.0 COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c DYD1_k127_2633294_15 926569.ANT_09760 1.58e-108 363.0 COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi 200795|Chloroflexi D Belongs to the SEDS family - - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE DYD1_k127_2633294_40 525903.Taci_1204 1.275e-13 76.0 COG0851@1|root,COG0851@2|Bacteria,3TBIQ@508458|Synergistetes 508458|Synergistetes D Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell minE - - ko:K03608 - - - - ko00000,ko03036,ko04812 - - - MinE DYD1_k127_2633294_14 926569.ANT_09740 2.515e-117 389.0 COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi 200795|Chloroflexi D Belongs to the ParA family minD - - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA DYD1_k127_2633294_28 926569.ANT_09730 1.966e-53 196.0 COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi 200795|Chloroflexi D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC - - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C,MinC_N DYD1_k127_2638902_7 926569.ANT_30350 2.744e-17 96.0 COG0745@1|root,COG0745@2|Bacteria 926569.ANT_30350|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_2638902_0 1247024.JRLH01000010_gene1213 3.641e-210 690.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria 1236|Gammaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 DYD1_k127_2638902_2 926569.ANT_30330 2.419e-152 509.0 COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi 200795|Chloroflexi S PFAM TPR repeat-containing protein - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8 DYD1_k127_2638902_3 926569.ANT_09470 1.176e-86 299.0 COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi 200795|Chloroflexi S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N DYD1_k127_2638902_8 406124.ACPC01000019_gene2733 3.389e-12 79.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR DYD1_k127_2638902_1 926550.CLDAP_17140 7.403e-156 504.0 COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi 200795|Chloroflexi S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 DYD1_k127_2638902_4 926569.ANT_19230 5.868e-49 182.0 COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi 200795|Chloroflexi U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 DYD1_k127_2638902_5 383372.Rcas_2148 4.338e-40 168.0 COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia 32061|Chloroflexia T histidine kinase A domain protein - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg DYD1_k127_2638902_10 1123270.ATUR01000007_gene1423 1.476e-09 71.0 COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TXBT@28211|Alphaproteobacteria,2K0YJ@204457|Sphingomonadales 204457|Sphingomonadales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - GGDEF,HATPase_c,HisKA,PAS_9 DYD1_k127_2638902_6 1128421.JAGA01000002_gene367 1.158e-17 93.0 COG0658@1|root,COG0658@2|Bacteria 2|Bacteria S establishment of competence for transformation comE - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B DYD1_k127_2667491_0 926569.ANT_06320 3.298e-133 443.0 COG0763@1|root,COG0763@2|Bacteria 2|Bacteria M lipid-A-disaccharide synthase activity - - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - Capsule_synth DYD1_k127_2667491_1 926569.ANT_06330 9.279e-74 277.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_2674799_25 926569.ANT_10090 1.816e-13 70.0 COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi 200795|Chloroflexi J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 DYD1_k127_2674799_3 926569.ANT_10100 2.832e-83 282.0 COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi 200795|Chloroflexi J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C DYD1_k127_2674799_10 926569.ANT_10110 4.466e-60 210.0 COG0197@1|root,COG0197@2|Bacteria,2G6NA@200795|Chloroflexi 200795|Chloroflexi J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 DYD1_k127_2674799_27 1382358.JHVN01000021_gene723 3.175e-09 61.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,21VXR@150247|Anoxybacillus 91061|Bacilli J Ribosomal L29 protein rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 DYD1_k127_2674799_23 926569.ANT_10130 8.609e-20 94.0 COG0186@1|root,COG0186@2|Bacteria,2G722@200795|Chloroflexi 200795|Chloroflexi J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 DYD1_k127_2674799_11 926569.ANT_10140 3.615e-59 209.0 COG0093@1|root,COG0093@2|Bacteria,2G6MZ@200795|Chloroflexi 200795|Chloroflexi J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 DYD1_k127_2674799_19 926569.ANT_10150 7.927e-42 156.0 COG0198@1|root,COG0198@2|Bacteria,2G750@200795|Chloroflexi 200795|Chloroflexi J One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 DYD1_k127_2674799_5 926569.ANT_10160 3.315e-77 265.0 COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi 200795|Chloroflexi J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C DYD1_k127_2674799_22 926569.ANT_10170 1.603e-20 93.0 COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi 200795|Chloroflexi J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 DYD1_k127_2674799_12 926569.ANT_10180 5.585e-58 204.0 COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi 200795|Chloroflexi J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 DYD1_k127_2674799_8 926569.ANT_10190 1.757e-65 229.0 COG0097@1|root,COG0097@2|Bacteria,2G6HZ@200795|Chloroflexi 200795|Chloroflexi J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 DYD1_k127_2674799_20 926569.ANT_10200 8.79e-40 151.0 COG0256@1|root,COG0256@2|Bacteria,2G6Y4@200795|Chloroflexi 200795|Chloroflexi J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p DYD1_k127_2674799_9 926569.ANT_10210 4.242e-65 227.0 COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi 200795|Chloroflexi J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C DYD1_k127_2674799_24 479434.Sthe_1054 3.992e-15 76.0 COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi,27YRK@189775|Thermomicrobia 189775|Thermomicrobia J Ribosomal protein L30p/L7e rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 DYD1_k127_2674799_14 926569.ANT_10230 4.236e-49 180.0 COG0200@1|root,COG0200@2|Bacteria,2G6XY@200795|Chloroflexi 200795|Chloroflexi J Binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A DYD1_k127_2674799_0 926569.ANT_10240 4.031e-168 541.0 COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi 200795|Chloroflexi U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY DYD1_k127_2674799_6 264732.Moth_2439 3.108e-67 235.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,42ES7@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - iHN637.CLJU_RS20110 ADK,ADK_lid DYD1_k127_2674799_2 926569.ANT_10260 1.119e-88 309.0 COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi 200795|Chloroflexi J TIGRFAM methionine aminopeptidase, type I - - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD1_k127_2674799_26 886293.Sinac_0464 2.09e-11 65.0 COG0257@1|root,COG0257@2|Bacteria,2J1IK@203682|Planctomycetes 203682|Planctomycetes J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 DYD1_k127_2674799_13 926569.ANT_10280 9.949e-56 197.0 COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi 200795|Chloroflexi J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 DYD1_k127_2674799_16 926569.ANT_10290 6.231e-48 175.0 COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi 200795|Chloroflexi J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 DYD1_k127_2674799_4 926569.ANT_10300 5.822e-82 277.0 COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi 200795|Chloroflexi J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 DYD1_k127_2674799_1 926569.ANT_10310 6.334e-140 452.0 COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi 200795|Chloroflexi K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L DYD1_k127_2674799_17 926569.ANT_10320 3.428e-43 161.0 COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi 200795|Chloroflexi J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 DYD1_k127_2674799_7 926569.ANT_10330 6.467e-66 235.0 COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi 200795|Chloroflexi J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 DYD1_k127_2674799_15 1415780.JPOG01000001_gene325 7.06e-49 180.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1X61V@135614|Xanthomonadales 135614|Xanthomonadales J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 DYD1_k127_2674799_21 926550.CLDAP_03790 4.358e-33 132.0 COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi 200795|Chloroflexi J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 DYD1_k127_2674799_18 926569.ANT_10380 3.758e-42 160.0 COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM MazG family protein - - - ko:K02499 - - - - ko00000,ko03036 - - - MazG,TP_methylase DYD1_k127_2679863_1 350058.Mvan_3244 3.042e-38 152.0 COG0500@1|root,COG2226@2|Bacteria,2GJUF@201174|Actinobacteria,236M1@1762|Mycobacteriaceae 201174|Actinobacteria Q Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_2679863_0 211165.AJLN01000015_gene2327 3.07e-50 185.0 COG0500@1|root,COG2226@2|Bacteria,1GCN5@1117|Cyanobacteria 1117|Cyanobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_31 DYD1_k127_2679863_2 1123242.JH636434_gene4709 1.984e-26 111.0 COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes 203682|Planctomycetes S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - - - - - - - - - - RRM_1 DYD1_k127_2679863_3 1121373.KB903642_gene3670 0.0008077 46.0 COG0484@1|root,COG0484@2|Bacteria,4NV0E@976|Bacteroidetes,47S5M@768503|Cytophagia 976|Bacteroidetes O heat shock protein binding - - - - - - - - - - - - - DYD1_k127_27001_13 552811.Dehly_1438 4.708e-32 129.0 2DNS7@1|root,32YWC@2|Bacteria 2|Bacteria S S23 ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_27001_0 926569.ANT_10460 8.112e-216 686.0 COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi 200795|Chloroflexi C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M DYD1_k127_27001_1 926569.ANT_10450 6.285e-211 667.0 COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi 200795|Chloroflexi C PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N DYD1_k127_27001_9 926569.ANT_10450 1.66e-66 230.0 COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi 200795|Chloroflexi C PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N DYD1_k127_27001_12 383372.Rcas_2095 1.306e-32 129.0 COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi,375VH@32061|Chloroflexia 32061|Chloroflexia C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD1_k127_27001_14 926569.ANT_10430 6.389e-30 128.0 COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi 200795|Chloroflexi C Belongs to the complex I subunit 6 family - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD1_k127_27001_3 926569.ANT_10420 1.621e-122 404.0 COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_27001_11 926569.ANT_10410 1.374e-37 144.0 COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 DYD1_k127_27001_4 926569.ANT_22610 5.517e-122 402.0 COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi 200795|Chloroflexi V PFAM Methicillin resistance protein - - - - - - - - - - - - FemAB DYD1_k127_27001_6 926569.ANT_22600 3.166e-104 353.0 COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi 200795|Chloroflexi V PFAM Methicillin resistance protein - - - - - - - - - - - - FemAB DYD1_k127_27001_10 404380.Gbem_3571 2.298e-53 196.0 COG4832@1|root,COG4832@2|Bacteria,1RBGY@1224|Proteobacteria 1224|Proteobacteria S GyrI-like small molecule binding domain - - - - - - - - - - - - GyrI-like DYD1_k127_27001_5 768671.ThimaDRAFT_1778 8.419e-113 372.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1X0CX@135613|Chromatiales 135613|Chromatiales E Pyridoxal-phosphate dependent enzyme - - 4.4.1.25 ko:K17950 ko00270,map00270 - R07634 RC01784 ko00000,ko00001,ko01000 - - - PALP DYD1_k127_27001_2 926569.ANT_23640 1.641e-171 556.0 COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi 200795|Chloroflexi T adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - FHA,GAF_2,GAF_3,Guanylate_cyc,PAS DYD1_k127_27001_8 1521187.JPIM01000001_gene834 1.698e-80 287.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase yghO - - - - - - - - - - - Acetyltransf_1 DYD1_k127_27001_7 926569.ANT_23650 6.094e-95 342.0 COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi 200795|Chloroflexi E PFAM transglutaminase domain protein - - - - - - - - - - - - DUF4129,Transglut_core DYD1_k127_2708747_3 1245469.S58_66500 1.186e-98 330.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TSE7@28211|Alphaproteobacteria,3JRVG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E amino acid livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_2708747_4 1380394.JADL01000002_gene1160 3.683e-97 335.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2U1BU@28211|Alphaproteobacteria,2JW92@204441|Rhodospirillales 204441|Rhodospirillales E ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran DYD1_k127_2708747_2 1380394.JADL01000002_gene1159 1.541e-121 397.0 COG0559@1|root,COG0559@2|Bacteria,1MXGK@1224|Proteobacteria,2TVKT@28211|Alphaproteobacteria,2JVW1@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 DYD1_k127_2708747_1 1380394.JADL01000002_gene1158 1.334e-121 400.0 COG4177@1|root,COG4177@2|Bacteria,1P0DF@1224|Proteobacteria,2TUBF@28211|Alphaproteobacteria,2JUXE@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 DYD1_k127_2708747_0 1037409.BJ6T_84510 1.015e-167 536.0 COG0683@1|root,COG0683@2|Bacteria,1MV1Z@1224|Proteobacteria,2TRTD@28211|Alphaproteobacteria,3JRR8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_2708747_5 330214.NIDE2980 7.569e-18 83.0 COG1830@1|root,COG1830@2|Bacteria,3J1DE@40117|Nitrospirae 40117|Nitrospirae G DeoC/LacD family aldolase - - 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - DeoC DYD1_k127_2722159_1 243231.GSU0775 5.785e-61 234.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase HAMP - - 2.7.13.3 ko:K02482 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,sCache_3_3 DYD1_k127_2722159_2 208439.AJAP_36740 5.528e-38 159.0 2DQGC@1|root,336PP@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4872) - - - - - - - - - - - - BtrH_N,DUF4872 DYD1_k127_2722159_0 861299.J421_0666 1.509e-111 371.0 COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes S cellulose binding - - - - - - - - - - - - - DYD1_k127_2722159_3 1382356.JQMP01000003_gene1357 7.57e-19 93.0 COG1977@1|root,COG1977@2|Bacteria,2GBBB@200795|Chloroflexi,27Z8W@189775|Thermomicrobia 189775|Thermomicrobia H ThiS family - - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD1_k127_2803683_4 926569.ANT_09210 4.428e-71 257.0 COG0745@1|root,COG2114@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP,dCache_1,dCache_3 DYD1_k127_2803683_0 926569.ANT_09640 1.222e-140 456.0 COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi 200795|Chloroflexi J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD1_k127_2803683_5 926569.ANT_09630 1.686e-55 206.0 COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi 200795|Chloroflexi J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 DYD1_k127_2803683_6 1382356.JQMP01000003_gene2404 3.373e-46 175.0 COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi,27Y7A@189775|Thermomicrobia 189775|Thermomicrobia J Telomere recombination - - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC DYD1_k127_2803683_7 926569.ANT_28940 3.863e-44 172.0 COG2382@1|root,COG2382@2|Bacteria 2|Bacteria P enterobactin catabolic process - - - ko:K07214 - - - - ko00000 - - - Esterase DYD1_k127_2803683_2 926569.ANT_07490 2.157e-85 291.0 COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi 200795|Chloroflexi P PFAM binding-protein-dependent transport systems inner membrane component - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_2803683_1 926569.ANT_07480 2.586e-102 343.0 COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi 200795|Chloroflexi P PFAM NMT1 THI5 like domain protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_2803683_3 1380394.JADL01000001_gene2547 3.235e-73 256.0 COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,2JW7Z@204441|Rhodospirillales 204441|Rhodospirillales P ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran DYD1_k127_2886713_1 326427.Cagg_0341 1.466e-33 139.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia 32061|Chloroflexia T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,HATPase_c,HisKA_3 DYD1_k127_2886713_0 324602.Caur_3230 1.345e-76 267.0 COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi,377YJ@32061|Chloroflexia 32061|Chloroflexia K Sigma-70, region 4 type 2 - - - ko:K11618 ko02020,map02020 M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg DYD1_k127_2886713_2 324602.Caur_3229 1.381e-10 73.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia 32061|Chloroflexia T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,HATPase_c,HisKA_3 DYD1_k127_2889345_1 926569.ANT_28020 1.04e-32 134.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM,Peptidase_M15_4 DYD1_k127_2889345_0 290397.Adeh_2994 1.543e-122 403.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WK79@28221|Deltaproteobacteria,2YV9G@29|Myxococcales 28221|Deltaproteobacteria H aminotransferase - - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD1_k127_2938731_16 566461.SSFG_05980 7.487e-17 80.0 2EPJ6@1|root,33H5U@2|Bacteria,2IT42@201174|Actinobacteria 201174|Actinobacteria S Unextendable partial coding region - - - - - - - - - - - - - DYD1_k127_2938731_19 1122921.KB898209_gene2653 5.937e-08 54.0 2BR0X@1|root,32JYC@2|Bacteria,1U1R4@1239|Firmicutes,4IB7I@91061|Bacilli,273UA@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_2938731_17 1121930.AQXG01000001_gene1488 1.665e-13 77.0 29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 DYD1_k127_2938731_15 1121271.AUCM01000004_gene1228 1.011e-19 94.0 COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain tcrX - - - - - - - - - - - Response_reg DYD1_k127_2938731_11 1227499.C493_09600 3.068e-35 157.0 COG1173@1|root,arCOG00748@2157|Archaea,2XUIX@28890|Euryarchaeota,23T5H@183963|Halobacteria 183963|Halobacteria P COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components nikC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N DYD1_k127_2938731_13 1502851.FG93_04007 7.326e-27 130.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria,3JSES@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EP Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - ko:K02033,ko:K13890 ko02010,ko02024,map02010,map02024 M00239,M00348 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.11 - - BPD_transp_1 DYD1_k127_2938731_10 402777.KB235903_gene1332 3.863e-50 199.0 COG1279@1|root,COG1279@2|Bacteria,1GQJ3@1117|Cyanobacteria,1HHX6@1150|Oscillatoriales 1117|Cyanobacteria S LysE type translocator - - - - - - - - - - - - LysE DYD1_k127_2938731_12 309801.trd_A0611 4.451e-33 135.0 COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YAV@189775|Thermomicrobia 189775|Thermomicrobia K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_2938731_14 1382356.JQMP01000001_gene846 5.09e-21 104.0 COG3806@1|root,COG3806@2|Bacteria,2GBHI@200795|Chloroflexi,27YJT@189775|Thermomicrobia 189775|Thermomicrobia T Anti-sigma-K factor rskA - - - - - - - - - - - - RskA,zf-HC2 DYD1_k127_2938731_21 383372.Rcas_0289 0.0005504 49.0 arCOG03922@1|root,33G2Q@2|Bacteria,2G9KY@200795|Chloroflexi,3760I@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function (DUF3054) - - - - - - - - - - - - DUF3054 DYD1_k127_2938731_8 926569.ANT_29500 1.54e-60 216.0 COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi 200795|Chloroflexi K sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_2938731_18 383372.Rcas_0730 2.001e-11 75.0 COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi,375WU@32061|Chloroflexia 32061|Chloroflexia K AntiSigma factor - - - - - - - - - - - - - DYD1_k127_2938731_9 926569.ANT_29480 2.606e-50 185.0 COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi 200795|Chloroflexi F Nudix hydrolase - - - - - - - - - - - - NUDIX DYD1_k127_2938731_2 1172180.KB911790_gene1226 6.419e-118 391.0 COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria 201174|Actinobacteria P Pfam Sodium hydrogen exchanger - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger DYD1_k127_2938731_4 926569.ANT_28060 5.259e-102 338.0 COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi 200795|Chloroflexi J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT DYD1_k127_2938731_3 926569.ANT_31100 1.954e-105 370.0 COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi 200795|Chloroflexi E PFAM extracellular solute-binding protein, family 5 - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_2938731_1 926550.CLDAP_11120 6.221e-144 464.0 COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi 200795|Chloroflexi P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_2938731_0 1173026.Glo7428_3203 2.435e-148 476.0 COG4608@1|root,COG4608@2|Bacteria,1G1Q0@1117|Cyanobacteria 1117|Cyanobacteria P Belongs to the ABC transporter superfamily - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_2938731_7 744872.Spica_2539 1.95e-74 273.0 COG4166@1|root,COG4166@2|Bacteria,2J687@203691|Spirochaetes 203691|Spirochaetes E extracellular solute-binding protein, family 5 oppA-1 - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 DYD1_k127_2938731_5 1449126.JQKL01000004_gene567 1.603e-87 301.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,268KP@186813|unclassified Clostridiales 186801|Clostridia EP Binding-protein-dependent transport system inner membrane component oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 DYD1_k127_2938731_6 1121324.CLIT_10c04120 2.502e-80 281.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,25SV4@186804|Peptostreptococcaceae 186801|Clostridia EP N-terminal TM domain of oligopeptide transport permease C oppC - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N DYD1_k127_2942057_4 717605.Theco_2465 7.473e-24 111.0 28KMW@1|root,303HV@2|Bacteria,1VJID@1239|Firmicutes,4HXA7@91061|Bacilli,2739W@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_2942057_1 1123487.KB892864_gene2136 1.108e-58 213.0 COG2334@1|root,COG2334@2|Bacteria,1R16N@1224|Proteobacteria,2W4AR@28216|Betaproteobacteria 28216|Betaproteobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH DYD1_k127_2942057_0 1396141.BATP01000058_gene1989 1e-71 248.0 COG4912@1|root,COG4912@2|Bacteria,46VM8@74201|Verrucomicrobia 74201|Verrucomicrobia L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation DYD1_k127_2942057_3 1122138.AQUZ01000052_gene8412 1.085e-25 110.0 COG3576@1|root,COG3576@2|Bacteria,2I46F@201174|Actinobacteria 201174|Actinobacteria S pyridoxamine 5-phosphate - - - - - - - - - - - - Putative_PNPOx DYD1_k127_2951089_2 926569.ANT_04910 8.542e-38 150.0 COG1765@1|root,COG1765@2|Bacteria,2G978@200795|Chloroflexi 200795|Chloroflexi O OsmC-like protein - - - ko:K07397 - - - - ko00000 - - - OsmC DYD1_k127_2951089_1 926569.ANT_22490 2.08e-62 223.0 COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi 200795|Chloroflexi D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA DYD1_k127_2951089_4 1501230.ET33_26280 2.737e-10 73.0 COG5652@1|root,COG5652@2|Bacteria,1VGDJ@1239|Firmicutes,4HNZ0@91061|Bacilli,26Z72@186822|Paenibacillaceae 91061|Bacilli S VanZ like family - - - - - - - - - - - - VanZ DYD1_k127_2951089_0 266117.Rxyl_2540 9.065e-195 628.0 COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria 84995|Rubrobacteria O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH DYD1_k127_2951089_3 1396141.BATP01000057_gene3037 7.325e-34 130.0 COG0449@1|root,COG0449@2|Bacteria,46S94@74201|Verrucomicrobia,2ITND@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glutamine amidotransferase domain - - - - - - - - - - - - GATase_6,SIS DYD1_k127_295940_2 1149133.ppKF707_3422 6.664e-107 365.0 COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,1RPZ2@1236|Gammaproteobacteria,1YEYV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_295940_0 1469245.JFBG01000014_gene2037 1.988e-138 445.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,1RQ0A@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K15552 ko00920,ko02010,map00920,map02010 M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 - - BPD_transp_1 DYD1_k127_295940_1 1469245.JFBG01000014_gene2038 1.094e-120 393.0 COG4525@1|root,COG4525@2|Bacteria,1QTUA@1224|Proteobacteria,1RPAF@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system tauB - 3.6.3.36 ko:K10831 ko00920,ko02010,map00920,map02010 M00435 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.1,3.A.1.17.4 - - ABC_tran DYD1_k127_295940_3 400682.PAC_15706569 3.146e-87 290.0 COG4521@1|root,2SA9K@2759|Eukaryota,3AMQS@33154|Opisthokonta,3C0J7@33208|Metazoa 33208|Metazoa P NMT1-like family - - - - - - - - - - - - NMT1,OpuAC DYD1_k127_2961466_9 351607.Acel_0986 2.319e-54 220.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4ERI4@85013|Frankiales 201174|Actinobacteria KLT Serine threonine protein kinase pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase DYD1_k127_2961466_6 717605.Theco_0041 3.65e-67 262.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,26QGU@186822|Paenibacillaceae 91061|Bacilli E ABC transporter substrate-binding protein dppE - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 DYD1_k127_2961466_14 489825.LYNGBM3L_49830 1.94e-22 109.0 COG2340@1|root,COG2340@2|Bacteria,1G4UZ@1117|Cyanobacteria,1HAAV@1150|Oscillatoriales 1117|Cyanobacteria Q Scp-like extracellular - - - - - - - - - - - - CAP,HemolysinCabind DYD1_k127_2961466_12 1122915.AUGY01000084_gene6180 2.894e-30 124.0 COG4430@1|root,COG4430@2|Bacteria,1VG0C@1239|Firmicutes,4HQHY@91061|Bacilli,277PA@186822|Paenibacillaceae 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - - DYD1_k127_2961466_3 1121918.ARWE01000001_gene50 2.629e-99 369.0 COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,1Q5XI@1224|Proteobacteria,437EC@68525|delta/epsilon subdivisions,2X2KQ@28221|Deltaproteobacteria,43VY4@69541|Desulfuromonadales 28221|Deltaproteobacteria P alginic acid biosynthetic process - - - - - - - - - - - - - DYD1_k127_2961466_13 926550.CLDAP_14620 8.371e-29 137.0 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Beta_helix,Peptidase_S74 DYD1_k127_2961466_11 1125863.JAFN01000001_gene2355 1.413e-41 179.0 COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1PFJ7@1224|Proteobacteria,42WVE@68525|delta/epsilon subdivisions 1224|Proteobacteria N domain, Protein - - - - - - - - - - - - - DYD1_k127_2961466_2 926569.ANT_27540 1.035e-119 393.0 COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi 200795|Chloroflexi E homoserine dehydrogenase metM - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 DYD1_k127_2961466_0 926569.ANT_12980 3.182e-300 955.0 COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi 200795|Chloroflexi O PFAM NHL repeat containing protein - - - - - - - - - - - - NHL,PMT_2 DYD1_k127_2961466_4 926569.ANT_27550 9.468e-90 301.0 COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi 200795|Chloroflexi BDLTU phosphatidylinositol kinase activity - - - - - - - - - - - - PI3_PI4_kinase DYD1_k127_2961466_7 926569.ANT_04570 9.357e-67 233.0 298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF3090) - - - - - - - - - - - - DUF3090 DYD1_k127_2961466_8 1128421.JAGA01000003_gene3534 1.69e-58 209.0 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity - - 3.1.3.3,3.1.3.73,5.4.2.12 ko:K02226,ko:K15634,ko:K22305 ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00122 R00582,R01518,R04594,R11173 RC00017,RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 DYD1_k127_2961466_1 926569.ANT_00900 7.563e-206 652.0 COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi 200795|Chloroflexi L PFAM AAA ATPase central domain protein - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N DYD1_k127_2961466_5 316274.Haur_3817 4.389e-70 248.0 COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi,3762A@32061|Chloroflexia 32061|Chloroflexia EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_2961466_10 926569.ANT_02780 1.61e-53 197.0 COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi 200795|Chloroflexi D PFAM Maf family protein maf - - ko:K06287 - - - - ko00000 - - - Maf DYD1_k127_2961466_15 926569.ANT_02790 9.681e-12 74.0 COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi 200795|Chloroflexi M NTF2-like N-terminal transpeptidase domain - - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - MecA_N,PBP_dimer,Transpeptidase DYD1_k127_2966748_3 552811.Dehly_0997 2.914e-29 127.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - 2.3.1.82 ko:K18815 - - - - br01600,ko00000,ko01000,ko01504 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 DYD1_k127_2966748_0 1121918.ARWE01000001_gene2996 8.992e-60 222.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,43U6N@69541|Desulfuromonadales 28221|Deltaproteobacteria M ATP-grasp domain - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD1_k127_2966748_1 926569.ANT_00330 1.525e-44 171.0 COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi 200795|Chloroflexi S PFAM LmbE family protein - - - - - - - - - - - - PIG-L DYD1_k127_2966748_2 1122138.AQUZ01000047_gene100 6.386e-31 126.0 COG5485@1|root,COG5485@2|Bacteria,2HPCH@201174|Actinobacteria,4DSK3@85009|Propionibacteriales 201174|Actinobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL DYD1_k127_2966748_4 1121930.AQXG01000007_gene409 4.482e-26 113.0 COG1695@1|root,COG1695@2|Bacteria,4PK5I@976|Bacteroidetes,1IZJS@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Transcriptional regulator PadR N-terminal-like - - - - - - - - - - - - PadR DYD1_k127_297232_29 1121422.AUMW01000012_gene2953 5.175e-12 69.0 COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267CM@186807|Peptococcaceae 186801|Clostridia T GAF domain - - - - - - - - - - - - GAF_2,HD DYD1_k127_297232_20 926569.ANT_08190 6.435e-25 106.0 COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi 200795|Chloroflexi K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD1_k127_297232_14 1121920.AUAU01000013_gene1720 1.389e-40 160.0 COG3613@1|root,COG3613@2|Bacteria 2|Bacteria F nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - - - - - - - - - - Nuc_deoxyrib_tr DYD1_k127_297232_13 290397.Adeh_1286 6.11e-48 185.0 COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales 28221|Deltaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_297232_9 96561.Dole_2131 7.422e-67 236.0 COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MKW3@213118|Desulfobacterales 28221|Deltaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 DYD1_k127_297232_25 877455.Metbo_0042 2.086e-17 91.0 COG0671@1|root,arCOG07501@2157|Archaea,2XYXG@28890|Euryarchaeota,23PN8@183925|Methanobacteria 183925|Methanobacteria I PFAM phosphatidate cytidylyltransferase - - - - - - - - - - - - - DYD1_k127_297232_19 926569.ANT_30850 5.774e-26 109.0 COG0694@1|root,COG0694@2|Bacteria 2|Bacteria O iron-sulfur cluster assembly nfuA - - - - - - - - - - - NifU DYD1_k127_297232_17 926569.ANT_30840 7.946e-34 136.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Fer4_7,HTH_Crp_2,cNMP_binding DYD1_k127_297232_2 926569.ANT_12730 2.223e-144 479.0 COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi 200795|Chloroflexi E TIGRFAM cysteine desulfurase family protein - - - - - - - - - - - - Aminotran_5 DYD1_k127_297232_15 479434.Sthe_1016 8.809e-37 147.0 COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi,27Y9U@189775|Thermomicrobia 189775|Thermomicrobia H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD1_k127_297232_1 926569.ANT_29620 1.243e-164 525.0 COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi 200795|Chloroflexi C PFAM Radical SAM domain protein - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM DYD1_k127_297232_23 926569.ANT_19040 5.438e-19 91.0 2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_297232_24 1206101.AZXC01000001_gene4316 1.593e-17 83.0 COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria 201174|Actinobacteria S Uncharacterized conserved protein (DUF2277) - - - - - - - - - - - - DUF2277 DYD1_k127_297232_0 926569.ANT_30160 6.628e-190 600.0 COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_297232_21 926569.ANT_00650 1.251e-24 114.0 COG2827@1|root,COG2827@2|Bacteria,2G9H6@200795|Chloroflexi 200795|Chloroflexi L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD1_k127_297232_18 742725.HMPREF9450_01364 1.489e-32 140.0 COG0499@1|root,COG0499@2|Bacteria,4P50E@976|Bacteroidetes,2G1VD@200643|Bacteroidia,22V89@171550|Rikenellaceae 976|Bacteroidetes H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine - - - - - - - - - - - - - DYD1_k127_297232_10 365044.Pnap_1340 4.039e-65 227.0 COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 DYD1_k127_297232_6 324602.Caur_2628 2.394e-92 319.0 COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi 200795|Chloroflexi Q PFAM Dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_297232_28 85643.Tmz1t_3037 2.42e-12 78.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,2KU90@206389|Rhodocyclales 206389|Rhodocyclales E Prephenate dehydrogenase tyrA - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH DYD1_k127_297232_11 926569.ANT_00670 4.357e-63 226.0 COG1994@1|root,COG1994@2|Bacteria,2G6VM@200795|Chloroflexi 200795|Chloroflexi S Peptidase M50 - - - - - - - - - - - - Peptidase_M50 DYD1_k127_297232_22 479434.Sthe_0412 9.762e-22 97.0 COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia 189775|Thermomicrobia S Bacterial protein of unknown function (DUF951) - - - - - - - - - - - - DUF951 DYD1_k127_297232_3 926569.ANT_00690 2.614e-113 377.0 COG0707@1|root,COG0707@2|Bacteria,2G6CA@200795|Chloroflexi 200795|Chloroflexi M Glycosyltransferase 28 domain - - 2.4.1.46 ko:K03715 ko00561,ko01100,map00561,map01100 - R02691 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT28 - Glyco_tran_28_C,MGDG_synth DYD1_k127_297232_26 867903.ThesuDRAFT_00714 2.233e-16 85.0 COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes 1239|Firmicutes S Ethyl tert-butyl ether degradation ethD - - - - - - - - - - - EthD DYD1_k127_297232_7 926569.ANT_29790 1.319e-82 284.0 COG0739@1|root,COG0739@2|Bacteria 2|Bacteria M heme binding - - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 DYD1_k127_297232_12 1120960.ATXG01000006_gene2205 5.449e-54 199.0 COG1028@1|root,COG1028@2|Bacteria,2GNM4@201174|Actinobacteria,4FTD6@85023|Microbacteriaceae 201174|Actinobacteria IQ KR domain - - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 DYD1_k127_297232_16 926569.ANT_27110 3.305e-34 139.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - - DYD1_k127_297232_4 926550.CLDAP_07100 5.142e-100 332.0 COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi 200795|Chloroflexi I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD1_k127_297232_8 926569.ANT_29760 1.092e-68 244.0 COG2746@1|root,COG2746@2|Bacteria 2|Bacteria V aminoglycoside 3-N-acetyltransferase activity yokD - 2.3.1.81 ko:K00662 - - - - ko00000,ko01000,ko01504 - - - Antibiotic_NAT DYD1_k127_297232_5 485913.Krac_12542 7.588e-99 336.0 COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi 200795|Chloroflexi C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD1_k127_297232_30 1211777.BN77_3679 2.34e-06 50.0 COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,2TT4T@28211|Alphaproteobacteria,4B9P6@82115|Rhizobiaceae 28211|Alphaproteobacteria GM NmrA-like family - - - - - - - - - - - - Epimerase,NAD_binding_10 DYD1_k127_3007784_6 926569.ANT_28020 9.747e-08 57.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM,Peptidase_M15_4 DYD1_k127_3007784_5 926550.CLDAP_33500 7.615e-61 220.0 COG1122@1|root,COG1122@2|Bacteria,2G6FK@200795|Chloroflexi 200795|Chloroflexi P ECF transporter, substrate-specific component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF_trnsprt DYD1_k127_3007784_4 926569.ANT_23190 2.442e-121 404.0 COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi 200795|Chloroflexi S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 DYD1_k127_3007784_3 926569.ANT_28150 3.035e-157 511.0 COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi 200795|Chloroflexi S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane - - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN DYD1_k127_3007784_1 926569.ANT_27910 1.868e-165 529.0 COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi 200795|Chloroflexi S Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 DYD1_k127_3007784_2 926569.ANT_27900 7.891e-163 522.0 COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi 200795|Chloroflexi S Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 DYD1_k127_3007784_0 926569.ANT_27890 6.809e-243 759.0 COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi 200795|Chloroflexi S PFAM ABC transporter related - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran DYD1_k127_3011670_1 330214.NIDE3473 1.379e-205 649.0 COG1538@1|root,COG1538@2|Bacteria,3J0N2@40117|Nitrospirae 40117|Nitrospirae M Evidence 2b Function of strongly homologous gene - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - OEP DYD1_k127_3011670_0 323848.Nmul_A0688 0.0 1039.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,3727K@32003|Nitrosomonadales 28216|Betaproteobacteria V Hydrophobe amphiphile efflux-1 HAE1 - - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD1_k127_3070131_0 886293.Sinac_0081 7.256e-210 656.0 COG4447@1|root,COG4447@2|Bacteria,2IXU6@203682|Planctomycetes 203682|Planctomycetes L cellulose binding - - - - - - - - - - - - - DYD1_k127_3070131_2 479434.Sthe_1273 8.319e-180 596.0 COG0277@1|root,COG0277@2|Bacteria 2|Bacteria C FAD linked oxidase domain protein - - - - - - - - - - - - BBE,FAD_binding_4 DYD1_k127_3070131_1 211165.AJLN01000153_gene659 5.181e-183 585.0 COG2270@1|root,COG2270@2|Bacteria,1G4W7@1117|Cyanobacteria 1117|Cyanobacteria S Major Facilitator Superfamily - - - ko:K18833 - - - - ko00000,ko01504,ko02000 2.A.1.21.2 - - MFS_1 DYD1_k127_3115920_2 1254432.SCE1572_35745 7.924e-101 349.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales 28221|Deltaproteobacteria T response regulator - - - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_3115920_3 926569.ANT_16900 1.167e-80 295.0 COG3852@1|root,COG3852@2|Bacteria,2G96T@200795|Chloroflexi 200795|Chloroflexi T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS DYD1_k127_3115920_1 926569.ANT_16910 7.122e-122 411.0 COG1508@1|root,COG1508@2|Bacteria,2G5VM@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM RNA polymerase sigma-54 factor, RpoN - - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD DYD1_k127_3115920_0 926569.ANT_16920 1.864e-156 501.0 COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs - - 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA DYD1_k127_311665_1 765420.OSCT_3196 1.211e-93 318.0 COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia 200795|Chloroflexi KLT Serine threonine protein kinase - - - - - - - - - - - - Pkinase DYD1_k127_311665_2 926569.ANT_22560 4.121e-87 300.0 COG0524@1|root,COG0524@2|Bacteria,2G8C3@200795|Chloroflexi 200795|Chloroflexi H PFAM PfkB domain protein - - 2.7.1.83 ko:K16328 ko00240,map00240 - R03315 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB DYD1_k127_311665_0 414684.RC1_0645 4.426e-94 318.0 COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria,2JR4R@204441|Rhodospirillales 204441|Rhodospirillales Q Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway psuG - 4.2.1.70 ko:K16329 ko00240,map00240 - R01055 RC00432,RC00433 ko00000,ko00001,ko01000 - - - Indigoidine_A DYD1_k127_311665_6 439235.Dalk_3860 6.987e-08 65.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - DUF2723,PMT_2 DYD1_k127_311665_4 326427.Cagg_0457 4.179e-53 211.0 COG1287@1|root,COG1287@2|Bacteria,2GA02@200795|Chloroflexi,377K4@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - DYD1_k127_311665_5 357808.RoseRS_1718 1.786e-41 173.0 COG1287@1|root,COG1807@1|root,COG1287@2|Bacteria,COG1807@2|Bacteria,2GAJ2@200795|Chloroflexi,3770X@32061|Chloroflexia 32061|Chloroflexia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - DYD1_k127_311665_3 383372.Rcas_0076 4.886e-59 216.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,3756Y@32061|Chloroflexia 32061|Chloroflexia C TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD1_k127_312166_3 234267.Acid_2815 1.805e-27 124.0 COG0477@1|root,COG0477@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 DYD1_k127_312166_2 525904.Tter_0400 2.715e-48 181.0 COG0613@1|root,COG0613@2|Bacteria 2|Bacteria Q PHP domain protein - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C DYD1_k127_312166_1 926569.ANT_22570 1.46e-92 327.0 COG0392@1|root,COG0392@2|Bacteria,2G6EN@200795|Chloroflexi 200795|Chloroflexi S PFAM conserved - - - - - - - - - - - - LPG_synthase_TM DYD1_k127_312166_0 309801.trd_0440 5.693e-176 560.0 COG2006@1|root,COG2006@2|Bacteria,2GA2Y@200795|Chloroflexi,27YWH@189775|Thermomicrobia 189775|Thermomicrobia S Domain of unknown function (DUF362) - - - - - - - - - - - - DUF362 DYD1_k127_3153849_2 926569.ANT_00200 5.628e-124 408.0 COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi 200795|Chloroflexi G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH DYD1_k127_3153849_7 292563.Cyast_0560 5.727e-71 252.0 COG1218@1|root,COG1218@2|Bacteria,1G1Z4@1117|Cyanobacteria 1117|Cyanobacteria P 3'(2'),5'-bisphosphate nucleotidase - - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P DYD1_k127_3153849_5 926569.ANT_03870 1.932e-104 369.0 COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi 200795|Chloroflexi S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_3153849_10 105420.BBPO01000049_gene1769 9.505e-10 67.0 COG2020@1|root,COG2020@2|Bacteria,2HUDA@201174|Actinobacteria,2NIQ9@228398|Streptacidiphilus 201174|Actinobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT DYD1_k127_3153849_8 1410634.JHVD01000007_gene1037 1.679e-69 243.0 COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4DNN6@85009|Propionibacteriales 201174|Actinobacteria T Transcriptional regulatory protein, C terminal regX3 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - ko:K07776 ko02020,map02020 M00443 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_3153849_9 1382306.JNIM01000001_gene3580 2.618e-52 199.0 COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi 200795|Chloroflexi T PFAM ATP-binding region, ATPase domain protein - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like DYD1_k127_3153849_1 765420.OSCT_1170 2.798e-132 430.0 COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia 32061|Chloroflexia P TIGRFAM phosphate binding protein - - - - - - - - - - - - PBP_like,PBP_like_2 DYD1_k127_3153849_3 765420.OSCT_1171 1.308e-119 394.0 COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi,375B0@32061|Chloroflexia 32061|Chloroflexia P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 DYD1_k127_3153849_0 316274.Haur_3999 7.597e-142 477.0 COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi,374ZR@32061|Chloroflexia 32061|Chloroflexia P TIGRFAM phosphate ABC transporter, inner membrane subunit PstA - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 DYD1_k127_3153849_4 926550.CLDAP_00810 9.643e-108 371.0 COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi 200795|Chloroflexi P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran DYD1_k127_3153849_6 926569.ANT_02660 1.524e-101 339.0 COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi 200795|Chloroflexi P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran DYD1_k127_3184387_12 926569.ANT_08430 1.712e-35 140.0 COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi 200795|Chloroflexi S Integral membrane protein DUF92 - - - - - - - - - - - - DUF92 DYD1_k127_3184387_1 926569.ANT_28990 1.008e-158 511.0 COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase DYD1_k127_3184387_5 368408.Tpen_1599 5.173e-88 306.0 arCOG00137@1|root,arCOG00137@2157|Archaea 2157|Archaea S MFS/sugar transport protein - - - - - - - - - - - - MFS_1 DYD1_k127_3184387_0 765420.OSCT_0207 2.634e-187 600.0 COG0747@1|root,COG0747@2|Bacteria,2G85H@200795|Chloroflexi,3773I@32061|Chloroflexia 32061|Chloroflexia E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_3184387_3 311402.Avi_5350 8.624e-138 447.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,4BBR1@82115|Rhizobiaceae 28211|Alphaproteobacteria EP ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02033,ko:K12369 ko02010,ko02024,map02010,map02024 M00239,M00324 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD1_k127_3184387_4 311402.Avi_5351 2.933e-126 412.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VETJ@28211|Alphaproteobacteria,4B73C@82115|Rhizobiaceae 28211|Alphaproteobacteria EP ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02034,ko:K12370 ko02010,ko02024,map02010,map02024 M00239,M00324 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N DYD1_k127_3184387_9 502025.Hoch_3168 8.277e-43 170.0 COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,43CNJ@68525|delta/epsilon subdivisions,2X7VW@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel DYD1_k127_3184387_6 452637.Oter_0266 4.991e-84 294.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups exoO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K16555,ko:K16564 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 DYD1_k127_3184387_15 926550.CLDAP_07270 3.053e-30 125.0 2DT85@1|root,33J4K@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3184387_13 926550.CLDAP_07260 5.449e-34 135.0 2E3MN@1|root,32YJW@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3184387_16 324602.Caur_0327 2.593e-28 117.0 COG1917@1|root,COG1917@2|Bacteria,2G7C7@200795|Chloroflexi,377HW@32061|Chloroflexia 32061|Chloroflexia S PFAM Cupin 2 conserved barrel domain protein - - - - - - - - - - - - - DYD1_k127_3184387_2 365044.Pnap_1326 1.327e-155 508.0 COG1622@1|root,COG2132@1|root,COG1622@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2VK95@28216|Betaproteobacteria 28216|Betaproteobacteria Q Nitrite reductase nirK - 1.3.3.5,1.7.2.1 ko:K00368,ko:K08100 ko00860,ko00910,ko01110,ko01120,map00860,map00910,map01110,map01120 M00529 R00783,R00785,R02394 RC00086,RC01983 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cytochrome_CBB3 DYD1_k127_3184387_19 1123237.Salmuc_03252 6.511e-07 57.0 2EKB5@1|root,3351G@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3184387_8 1121033.AUCF01000026_gene2970 2.595e-51 196.0 COG0664@1|root,COG0664@2|Bacteria,1NPY0@1224|Proteobacteria,2TT13@28211|Alphaproteobacteria,2JS8J@204441|Rhodospirillales 204441|Rhodospirillales K Cyclic nucleotide-monophosphate binding domain - - - ko:K21564 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding DYD1_k127_3184387_10 926569.ANT_03710 9.05e-43 164.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - 2.1.1.334 ko:K21310 ko00920,map00920 - R11546 RC02653 ko00000,ko00001,ko01000 - - - NnrU,PEMT DYD1_k127_3184387_11 37919.EP51_17380 2.179e-36 145.0 COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4G8U5@85025|Nocardiaceae 201174|Actinobacteria FG Scavenger mRNA decapping enzyme C-term binding - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT DYD1_k127_3184387_7 926569.ANT_17610 1.05e-60 219.0 COG1611@1|root,COG1611@2|Bacteria,2G6P1@200795|Chloroflexi 200795|Chloroflexi S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD1_k127_3214774_9 479434.Sthe_3264 1.541e-92 315.0 COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,27XIQ@189775|Thermomicrobia 189775|Thermomicrobia J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT DYD1_k127_3214774_20 367299.JOEE01000004_gene1183 1.585e-22 105.0 COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4FHNM@85021|Intrasporangiaceae 201174|Actinobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 DYD1_k127_3214774_11 926569.ANT_20930 1.509e-82 289.0 COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi 200795|Chloroflexi M glycosyl transferase group 1 - - 2.4.1.345 ko:K08256 - - R11702 - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 DYD1_k127_3214774_4 1128421.JAGA01000002_gene1294 1.594e-124 412.0 COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria 2|Bacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_3214774_3 1128421.JAGA01000002_gene1295 1.63e-127 417.0 COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria 2|Bacteria E Branched-chain amino acid transport system / permease component livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_3214774_2 1128421.JAGA01000002_gene1296 1.623e-134 447.0 COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria 2|Bacteria U Branched-chain amino acid transport system / permease component livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_3214774_7 926550.CLDAP_29810 2.501e-100 334.0 COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi 200795|Chloroflexi E PFAM ABC transporter related - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_3214774_8 1128421.JAGA01000002_gene1298 4.465e-97 326.0 COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria 2|Bacteria E ABC transporter livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD1_k127_3214774_0 869210.Marky_1927 4.748e-190 606.0 COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E COG0076 Glutamate decarboxylase and related PLP-dependent - - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC DYD1_k127_3214774_10 1499967.BAYZ01000065_gene6085 2.707e-85 295.0 COG2423@1|root,COG2423@2|Bacteria,2NPI5@2323|unclassified Bacteria 2|Bacteria E Ornithine cyclodeaminase/mu-crystallin family rapL - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_3214774_1 1173022.Cri9333_0749 4.293e-150 481.0 COG0667@1|root,COG0667@2|Bacteria,1G3WV@1117|Cyanobacteria,1HH84@1150|Oscillatoriales 1117|Cyanobacteria C Aldo/keto reductase family - - 1.1.1.91 ko:K05882 - - - - ko00000,ko01000 - - - Aldo_ket_red DYD1_k127_3214774_6 309801.trd_0889 1.158e-104 352.0 COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27YWR@189775|Thermomicrobia 189775|Thermomicrobia E NAD(P)-binding Rossmann-like domain - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO DYD1_k127_3214774_5 926569.ANT_21060 5.645e-116 384.0 COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi 200795|Chloroflexi S PFAM molybdopterin binding domain - - - - - - - - - - - - CinA,MoCF_biosynth DYD1_k127_3214774_15 246197.MXAN_5993 8.548e-50 180.0 COG0251@1|root,COG0251@2|Bacteria,1RES6@1224|Proteobacteria,435VN@68525|delta/epsilon subdivisions,2X0B9@28221|Deltaproteobacteria,2Z1FV@29|Myxococcales 28221|Deltaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD1_k127_3214774_24 926569.ANT_03690 0.0003354 48.0 COG2234@1|root,COG2234@2|Bacteria 2|Bacteria DZ aminopeptidase activity - - 3.4.11.10,3.4.11.24,3.4.11.6 ko:K19701,ko:K19702 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M28 DYD1_k127_3214774_21 1144664.F973_02005 4.804e-22 100.0 COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SAT7@1236|Gammaproteobacteria,3NNGV@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF559) - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - DUF559 DYD1_k127_3214774_18 926569.ANT_11850 3.371e-37 145.0 COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi 200795|Chloroflexi T cheY-homologous receiver domain - - - ko:K11443 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg DYD1_k127_3214774_14 926569.ANT_11840 3.753e-59 209.0 COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi 200795|Chloroflexi T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_3214774_17 926569.ANT_11830 1.793e-46 189.0 COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity virA - 2.7.13.3,4.6.1.1 ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819 ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213 M00471,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000 - - - GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1 DYD1_k127_3214774_23 596151.DesfrDRAFT_2910 6.126e-07 63.0 COG0840@1|root,COG0840@2|Bacteria,1N10Q@1224|Proteobacteria,435RW@68525|delta/epsilon subdivisions,2X06J@28221|Deltaproteobacteria,2MAVB@213115|Desulfovibrionales 28221|Deltaproteobacteria NT transmembrane signaling receptor activity - - - - - - - - - - - - - DYD1_k127_3214774_16 926569.ANT_11800 3.455e-49 202.0 COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K07638,ko:K07673,ko:K21009 ko02020,ko02025,ko02026,map02020,map02025,map02026 M00445,M00471,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE DYD1_k127_3214774_22 740709.A10D4_08517 4.65e-07 64.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QF28@267893|Idiomarinaceae 1236|Gammaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - CHASE4,EAL,GAF_2,GGDEF DYD1_k127_3214774_13 926569.ANT_11800 1.228e-59 236.0 COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K07638,ko:K07673,ko:K21009 ko02020,ko02025,ko02026,map02020,map02025,map02026 M00445,M00471,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE DYD1_k127_3214774_19 926569.ANT_11780 7.202e-37 162.0 COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - - - - - - - - - - - HATPase_c,HisKA,Response_reg DYD1_k127_3214774_12 926569.ANT_11790 3.155e-68 242.0 COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi 200795|Chloroflexi D PFAM Cobyrinic acid a,c-diamide synthase - - - - - - - - - - - - AAA_31 DYD1_k127_3214774_25 1238182.C882_0838 0.000351 51.0 COG2199@1|root,COG5000@1|root,COG3706@2|Bacteria,COG5000@2|Bacteria,1MZV7@1224|Proteobacteria,2TZSN@28211|Alphaproteobacteria,2JVPG@204441|Rhodospirillales 204441|Rhodospirillales T PAS fold - - - - - - - - - - - - GGDEF,PAS_7 DYD1_k127_3226441_6 314231.FP2506_03795 7.244e-05 48.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,2PIZ6@255475|Aurantimonadaceae 28211|Alphaproteobacteria E Histidine biosynthesis protein hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD1_k127_3226441_3 1283283.ATXA01000001_gene587 9.626e-69 242.0 COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria 201174|Actinobacteria M Choline ethanolamine kinase - - - - - - - - - - - - APH,Choline_kinase DYD1_k127_3226441_4 1283283.ATXA01000001_gene587 3.095e-59 216.0 COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria 201174|Actinobacteria M Choline ethanolamine kinase - - - - - - - - - - - - APH,Choline_kinase DYD1_k127_3226441_5 1173024.KI912151_gene1606 5.322e-48 189.0 COG3247@1|root,COG3247@2|Bacteria,1G652@1117|Cyanobacteria,1JJJ3@1189|Stigonemataceae 1117|Cyanobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 DYD1_k127_3226441_2 1321778.HMPREF1982_01435 2.175e-75 268.0 COG0477@1|root,COG2814@2|Bacteria,1VB8Y@1239|Firmicutes,24KIW@186801|Clostridia 186801|Clostridia EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD1_k127_3226441_1 1217720.ALOX01000011_gene2503 7.492e-181 583.0 COG1502@1|root,COG1502@2|Bacteria,1R4EZ@1224|Proteobacteria,2U0UJ@28211|Alphaproteobacteria,2JXF7@204441|Rhodospirillales 204441|Rhodospirillales I PLD-like domain - - - - - - - - - - - - PLDc_2 DYD1_k127_3226441_0 452637.Oter_3899 6.236e-201 643.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,46UA9@74201|Verrucomicrobia,3K7MZ@414999|Opitutae 414999|Opitutae P Citrate transporter - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C DYD1_k127_3230213_10 926569.ANT_18980 5.071e-61 212.0 COG0080@1|root,COG0080@2|Bacteria,2G6FF@200795|Chloroflexi 200795|Chloroflexi J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N DYD1_k127_3230213_8 1128421.JAGA01000002_gene1604 8.625e-95 316.0 COG0081@1|root,COG0081@2|Bacteria,2NNK6@2323|unclassified Bacteria 2|Bacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 DYD1_k127_3230213_16 926569.ANT_18960 8.491e-31 128.0 COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi 200795|Chloroflexi J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 DYD1_k127_3230213_13 926569.ANT_18950 1.67e-44 165.0 COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi 200795|Chloroflexi J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N DYD1_k127_3230213_7 926569.ANT_28720 4.387e-100 330.0 COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi 200795|Chloroflexi K Two component transcriptional regulator, winged helix family - - - ko:K07669 ko02020,map02020 M00460 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_3230213_6 926569.ANT_28730 9.959e-107 362.0 COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi 200795|Chloroflexi T histidine kinase HAMP region domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA DYD1_k127_3230213_17 13689.BV96_04131 2.227e-10 70.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2U1CW@28211|Alphaproteobacteria,2K2MA@204457|Sphingomonadales 204457|Sphingomonadales M Transglycosylase SLT domain - - - - - - - - - - - - SLT DYD1_k127_3230213_11 329726.AM1_4674 2.09e-46 179.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi DYD1_k127_3230213_9 926560.KE387023_gene3292 1.235e-64 230.0 COG3358@1|root,COG3358@2|Bacteria,1WKRG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 DYD1_k127_3230213_4 926569.ANT_02010 2.614e-122 396.0 COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi 200795|Chloroflexi I Coenzyme A transferase - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD1_k127_3230213_3 96561.Dole_2515 1.341e-131 441.0 COG0438@1|root,COG0438@2|Bacteria,1R8YI@1224|Proteobacteria,42N8I@68525|delta/epsilon subdivisions,2WIYJ@28221|Deltaproteobacteria,2MMJB@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 DYD1_k127_3230213_15 926550.CLDAP_06980 1.013e-39 155.0 COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi 200795|Chloroflexi G Belongs to the phosphoglycerate mutase family - - 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 DYD1_k127_3230213_0 926550.CLDAP_06970 4.409e-212 676.0 COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups gpgS - 2.4.1.266,2.4.1.268 ko:K09118,ko:K13693,ko:K21349 - - - - ko00000,ko01000,ko01003 - GT81 - Glycos_transf_2,Usp DYD1_k127_3230213_5 1128421.JAGA01000003_gene2708 1.524e-110 370.0 COG0438@1|root,COG0438@2|Bacteria,2NQV5@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase Family 4 - - 2.4.1.270 ko:K21369 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_3230213_1 1295642.H839_06084 1.739e-154 507.0 COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,4HDDA@91061|Bacilli 91061|Bacilli G Sucrose glucosyltransferase gtfA - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase DYD1_k127_3230213_2 926569.ANT_02020 2.49e-149 477.0 COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi 200795|Chloroflexi I Coenzyme A transferase - - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD1_k127_3230213_14 926569.ANT_02430 2.98e-44 170.0 2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_324104_0 1382306.JNIM01000001_gene1819 5.09e-55 208.0 COG3509@1|root,COG3509@2|Bacteria,2G91Y@200795|Chloroflexi 200795|Chloroflexi Q Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd DYD1_k127_3251537_1 926569.ANT_05360 4.002e-74 268.0 COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi 200795|Chloroflexi BK Radical_SAM C-terminal domain - - 2.3.1.48 ko:K07739 - - - - ko00000,ko01000,ko03016,ko03036 - - - Acetyltransf_1,Radical_SAM,Radical_SAM_C DYD1_k127_3251537_2 926569.ANT_05350 9.046e-53 195.0 COG0500@1|root,COG0500@2|Bacteria 2|Bacteria Q methyltransferase activity bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 DYD1_k127_3251537_0 886293.Sinac_7570 3.007e-166 535.0 COG2242@1|root,COG2242@2|Bacteria,2J25Y@203682|Planctomycetes 203682|Planctomycetes H protein methyltransferase activity - - - - - - - - - - - - - DYD1_k127_3251537_3 661478.OP10G_0619 8.874e-33 136.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase DYD1_k127_3253591_0 926569.ANT_01410 2.141e-163 519.0 COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi 200795|Chloroflexi P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_3253591_1 926569.ANT_01400 2.985e-148 477.0 COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi 200795|Chloroflexi P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY DYD1_k127_3253591_2 247633.GP2143_09330 4.322e-07 59.0 COG2010@1|root,COG2010@2|Bacteria,1QVK1@1224|Proteobacteria,1RYEK@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrome_CBB3 DYD1_k127_3271642_0 543632.JOJL01000113_gene8438 1.777e-170 552.0 COG1321@1|root,COG1321@2|Bacteria,2GN2R@201174|Actinobacteria 201174|Actinobacteria K iron dependent repressor - - - - - - - - - - - - - DYD1_k127_3271642_1 266265.Bxe_A2438 1.086e-06 54.0 2EKCB@1|root,33E2M@2|Bacteria,1NGV2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_327363_0 926569.ANT_16820 7.734e-46 169.0 COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi 200795|Chloroflexi S PFAM metallophosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos DYD1_k127_327363_2 187272.Mlg_2320 5.855e-08 57.0 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1WVXE@135613|Chromatiales 135613|Chromatiales M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose - - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom DYD1_k127_327363_1 926569.ANT_20000 1.021e-45 173.0 COG0241@1|root,COG0241@2|Bacteria,2G6V8@200795|Chloroflexi 200795|Chloroflexi E Histidinol-phosphate phosphatase family protein gmhB - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Glycos_transf_2,Hydrolase_like DYD1_k127_327363_3 620914.JH621246_gene2708 1.382e-07 63.0 COG3055@1|root,COG5492@1|root,COG3055@2|Bacteria,COG5492@2|Bacteria,4PHYE@976|Bacteroidetes,1IHIJ@117743|Flavobacteriia,2YKAZ@290174|Aquimarina 976|Bacteroidetes N Kelch motif - - - - - - - - - - - - Kelch_1,Kelch_6 DYD1_k127_3283853_5 926569.ANT_06220 1.72e-44 166.0 COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi 200795|Chloroflexi L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB DYD1_k127_3283853_9 1191523.MROS_0258 4.692e-17 85.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.11.1,4.6.1.1 ko:K01768,ko:K12132 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001 - - - DUF3467 DYD1_k127_3283853_4 1128421.JAGA01000002_gene1417 2.53e-60 216.0 COG2178@1|root,COG2178@2|Bacteria,2NR1U@2323|unclassified Bacteria 2|Bacteria J PFAM Translin - - - ko:K07477 - - - - ko00000 - - - - DYD1_k127_3283853_6 316274.Haur_2838 8.491e-31 128.0 COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi,375P8@32061|Chloroflexia 32061|Chloroflexia L Domain of unknown function DUF83 - - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - Cas_Cas4 DYD1_k127_3283853_2 926569.ANT_00510 1.758e-85 293.0 COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi 200795|Chloroflexi F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase DYD1_k127_3283853_7 926569.ANT_00520 3.746e-30 135.0 COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi 200795|Chloroflexi NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - zf-B_box DYD1_k127_3283853_0 926569.ANT_00530 5.813e-181 582.0 COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi 200795|Chloroflexi L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N DYD1_k127_3283853_8 1122609.AUGT01000020_gene1126 1.54e-22 114.0 COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4DWWD@85009|Propionibacteriales 201174|Actinobacteria Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_3283853_3 266117.Rxyl_0848 2.286e-75 261.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria 84995|Rubrobacteria V PFAM ABC transporter related - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_3283853_1 946483.Cenrod_1211 2.415e-88 304.0 COG1748@1|root,COG1748@2|Bacteria 2|Bacteria E saccharopine dehydrogenase activity - - 1.5.1.7 ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715 RC00217,RC01532 ko00000,ko00001,ko00002,ko01000 - - - DUF4166,Sacchrp_dh_NADP DYD1_k127_3302510_3 215803.DB30_2247 6.177e-19 91.0 COG4576@1|root,COG4576@2|Bacteria,1Q0YX@1224|Proteobacteria,434YC@68525|delta/epsilon subdivisions,2WZ99@28221|Deltaproteobacteria,2Z1MJ@29|Myxococcales 28221|Deltaproteobacteria CQ Ethanolamine utilisation protein EutN/carboxysome - - - - - - - - - - - - EutN_CcmL DYD1_k127_3302510_4 1131730.BAVI_09011 3.052e-13 73.0 COG4576@1|root,COG4576@2|Bacteria,1UAHB@1239|Firmicutes,4IKVT@91061|Bacilli,1ZHYG@1386|Bacillus 91061|Bacilli CQ Ethanolamine utilisation protein EutN/carboxysome - - - - - - - - - - - - EutN_CcmL DYD1_k127_3302510_1 1121428.DESHY_110512___1 9.382e-74 256.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae 186801|Clostridia G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM DYD1_k127_3302510_0 1121324.CLIT_10c01870 1.346e-140 463.0 COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia 186801|Clostridia V Psort location Cytoplasmic, score - - - - - - - - - - - - Beta-lactamase DYD1_k127_3302510_2 1121324.CLIT_10c01870 7.169e-53 194.0 COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia 186801|Clostridia V Psort location Cytoplasmic, score - - - - - - - - - - - - Beta-lactamase DYD1_k127_3321223_1 589924.Ferp_1758 1.005e-99 336.0 COG0407@1|root,arCOG03323@2157|Archaea,2XV21@28890|Euryarchaeota 28890|Euryarchaeota H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 2.1.1.246,4.1.1.37 ko:K01599,ko:K14080 ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200 M00121,M00356 R03197,R04972,R09098,R10000 RC00035,RC00872,RC01144,RC02440 ko00000,ko00001,ko00002,ko01000 - - - URO-D DYD1_k127_3321223_0 1121430.JMLG01000016_gene367 7.115e-226 723.0 COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,260RG@186807|Peptococcaceae 186801|Clostridia C PFAM 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - DUF4445,Fer2 DYD1_k127_3321223_2 760568.Desku_0058 5.051e-95 321.0 COG1962@1|root,COG1962@2|Bacteria,1UYYD@1239|Firmicutes,24AC2@186801|Clostridia,26150@186807|Peptococcaceae 186801|Clostridia H Tetrahydromethanopterin S-methyltransferase MtrH subunit - - 2.1.1.86 ko:K00584 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00357,M00567 R04347 RC00035,RC00113,RC02892 ko00000,ko00001,ko00002,ko01000 - - - MtrH DYD1_k127_3321223_3 760568.Desku_0060 7.213e-68 240.0 COG0407@1|root,COG0407@2|Bacteria,1UYXW@1239|Firmicutes,25DH8@186801|Clostridia,264CR@186807|Peptococcaceae 186801|Clostridia H Uroporphyrinogen decarboxylase (URO-D) - - 2.1.1.246 ko:K14080 ko00680,ko01120,ko01200,map00680,map01120,map01200 M00356 R09098,R10000 RC00035,RC01144,RC02440 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,URO-D DYD1_k127_3371590_2 1540221.JQNI01000002_gene758 9.668e-06 53.0 COG0477@1|root,COG2814@2|Bacteria,1WJCM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD1_k127_3371590_1 525904.Tter_0584 5.909e-65 235.0 COG2041@1|root,COG2041@2|Bacteria,2NQ7J@2323|unclassified Bacteria 2|Bacteria S Oxidoreductase molybdopterin binding domain yedY - 1.8.3.1 ko:K00387,ko:K07147 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00533 RC00168 ko00000,ko00001,ko01000 - - - Mo-co_dimer,Oxidored_molyb DYD1_k127_3371590_3 247490.KSU1_D0430 1.948e-05 55.0 COG3005@1|root,COG3303@1|root,COG3005@2|Bacteria,COG3303@2|Bacteria,2J2KM@203682|Planctomycetes 203682|Planctomycetes CP NapC/NirT cytochrome c family, N-terminal region - - - - - - - - - - - - Cytochrom_NNT DYD1_k127_3371590_0 926569.ANT_28210 1.659e-180 580.0 COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi 200795|Chloroflexi G SMART alpha amylase catalytic sub domain - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459,Malt_amylase_C DYD1_k127_3371590_4 1261545.MBE-HAL_1565 2.975e-05 49.0 COG0526@1|root,arCOG01972@2157|Archaea,2XZ0C@28890|Euryarchaeota,23WWM@183963|Halobacteria 183963|Halobacteria O COG0526 Thiol-disulfide isomerase and thioredoxins trxA1 - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_3388308_2 649638.Trad_2778 9.782e-05 53.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1WIB3@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3 DYD1_k127_3388308_0 1150864.MILUP08_43876 4.739e-15 80.0 2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4DE78@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_344305_3 926550.CLDAP_07090 1.404e-169 549.0 COG0665@1|root,COG0665@2|Bacteria 2|Bacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO DYD1_k127_344305_22 1499967.BAYZ01000145_gene6205 5.358e-16 88.0 COG0801@1|root,COG0801@2|Bacteria 2|Bacteria H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity folK GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iSBO_1134.SBO_0131 FolB,HPPK DYD1_k127_344305_18 344747.PM8797T_30012 5.041e-33 133.0 COG1539@1|root,COG1539@2|Bacteria 2|Bacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 ko:K01633,ko:K07589 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073,R11082 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB DYD1_k127_344305_14 861299.J421_3591 1.689e-48 182.0 COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes 142182|Gemmatimonadetes IQ KR domain - - 1.5.1.33 ko:K03793 - - - - ko00000,ko01000 - - - adh_short_C2 DYD1_k127_344305_8 324602.Caur_2641 2.049e-74 255.0 COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia 32061|Chloroflexia H PFAM GTP cyclohydrolase I folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI DYD1_k127_344305_12 926569.ANT_18550 2.927e-51 193.0 COG1752@1|root,COG1752@2|Bacteria,2G70S@200795|Chloroflexi 200795|Chloroflexi S PFAM Patatin - - - ko:K07001 - - - - ko00000 - - - Patatin DYD1_k127_344305_23 1051632.TPY_0736 7.399e-16 86.0 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,24N6D@186801|Clostridia 186801|Clostridia S Dienelactone hydrolase family - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH DYD1_k127_344305_0 926569.ANT_18080 8.955e-284 886.0 COG0021@1|root,COG0021@2|Bacteria,2G63Z@200795|Chloroflexi 200795|Chloroflexi G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N DYD1_k127_344305_15 1142394.PSMK_26510 5.837e-48 182.0 COG0698@1|root,COG0698@2|Bacteria,2IZSB@203682|Planctomycetes 203682|Planctomycetes G Ribose/Galactose Isomerase - - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB DYD1_k127_344305_2 926569.ANT_18060 5.192e-242 780.0 COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi 200795|Chloroflexi G Belongs to the GPI family pgi - 2.2.1.2,5.3.1.9 ko:K01810,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI,TAL_FSA DYD1_k127_344305_5 219305.MCAG_05078 3.136e-89 313.0 COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria,4D9VR@85008|Micromonosporales 201174|Actinobacteria S Calcineurin-like phosphoesterase - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Metallophos DYD1_k127_344305_26 562970.Btus_0208 6.189e-05 54.0 28NT3@1|root,2ZBRV@2|Bacteria,1V1C2@1239|Firmicutes,4HFYQ@91061|Bacilli,27A60@186823|Alicyclobacillaceae 91061|Bacilli S YwiC-like protein - - - - - - - - - - - - YwiC DYD1_k127_344305_19 665571.STHERM_c00770 1.199e-30 138.0 COG2199@1|root,COG3706@2|Bacteria,2J8AQ@203691|Spirochaetes 203691|Spirochaetes T diguanylate cyclase - - - - - - - - - - - - CBS,GGDEF DYD1_k127_344305_9 1489678.RDMS_08810 7.148e-69 243.0 COG2191@1|root,COG2191@2|Bacteria 2|Bacteria C Formylmethanofuran dehydrogenase, subunit e - - 1.2.7.12 ko:K11261 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R03015,R08060,R11743 RC00197,RC00323 ko00000,ko00001,ko00002,ko01000 - - - FmdE,zf-dskA_traR DYD1_k127_344305_24 1232410.KI421413_gene911 4.801e-15 84.0 COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions,2WRHY@28221|Deltaproteobacteria,43UPC@69541|Desulfuromonadales 28221|Deltaproteobacteria C Rieske [2Fe-2S] domain pcmE - 1.10.9.1 ko:K02636,ko:K03886 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00151,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske DYD1_k127_344305_7 913865.DOT_4633 1.546e-74 267.0 COG3303@1|root,COG3303@2|Bacteria,1VTAV@1239|Firmicutes,24ZND@186801|Clostridia,264N1@186807|Peptococcaceae 186801|Clostridia P Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - - DYD1_k127_344305_11 596151.DesfrDRAFT_0649 2.75e-54 203.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria,2MEFN@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM Cytochrome b b6 domain cbcP - - - - - - - - - - - Cytochrom_B_N_2,Cytochrome_B DYD1_k127_344305_17 1121459.AQXE01000019_gene1897 1.188e-39 160.0 COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,42MVF@68525|delta/epsilon subdivisions,2WN3G@28221|Deltaproteobacteria,2M8G0@213115|Desulfovibrionales 28221|Deltaproteobacteria C Prokaryotic cytochrome b561 - - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Ni_hydr_CYTB DYD1_k127_344305_10 768706.Desor_3576 2.679e-61 220.0 COG0437@1|root,COG0437@2|Bacteria,1V35R@1239|Firmicutes,24GWA@186801|Clostridia,266YV@186807|Peptococcaceae 186801|Clostridia C 4Fe-4S binding domain - - - ko:K07307,ko:K08358 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R09501,R10150 RC02555,RC03109 ko00000,ko00001,ko02000 5.A.3.10,5.A.3.3 - - Fer4_11,Fer4_3,Fer4_4,Fer4_7 DYD1_k127_344305_1 768706.Desor_3577 9.134e-261 824.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,2605J@186807|Peptococcaceae 186801|Clostridia C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.5,1.8.5.6 ko:K08352,ko:K21307 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R10149,R11487 RC00168,RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal DYD1_k127_344305_13 646529.Desaci_3272 5.575e-50 184.0 COG2391@1|root,COG2391@2|Bacteria,1VJEX@1239|Firmicutes,25I6C@186801|Clostridia,266AI@186807|Peptococcaceae 186801|Clostridia S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp DYD1_k127_344305_16 913865.DOT_4642 3.652e-40 155.0 COG2391@1|root,COG2391@2|Bacteria,1VDTV@1239|Firmicutes,24QRU@186801|Clostridia,266NH@186807|Peptococcaceae 186801|Clostridia S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp DYD1_k127_344305_20 913865.DOT_4643 2.159e-25 117.0 2ENTF@1|root,33GEM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_344305_21 1123024.AUII01000052_gene3908 6.107e-25 108.0 COG0640@1|root,COG0640@2|Bacteria,2IKPW@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator, arsR family - - - - - - - - - - - - HTH_5 DYD1_k127_344305_6 1254432.SCE1572_20265 4.212e-84 289.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2YV0S@29|Myxococcales 28221|Deltaproteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_344305_4 1254432.SCE1572_20260 6.743e-94 314.0 COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria,2Z08T@29|Myxococcales 28221|Deltaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_3508283_2 479434.Sthe_2959 2.694e-33 132.0 COG1977@1|root,COG1977@2|Bacteria,2G6VH@200795|Chloroflexi 200795|Chloroflexi H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - - - - - - - - - - - DYD1_k127_3508283_0 290397.Adeh_1998 1.909e-48 192.0 COG4585@1|root,COG4585@2|Bacteria,1N0JE@1224|Proteobacteria,42UG3@68525|delta/epsilon subdivisions,2WQFT@28221|Deltaproteobacteria,2Z1DF@29|Myxococcales 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA_3 DYD1_k127_3508283_1 1382306.JNIM01000001_gene1045 1.439e-36 141.0 COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi 200795|Chloroflexi K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg DYD1_k127_351282_4 926569.ANT_10090 3.713e-41 157.0 COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi 200795|Chloroflexi J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 DYD1_k127_351282_3 525904.Tter_0719 1.47e-44 163.0 COG0185@1|root,COG0185@2|Bacteria,2NPIV@2323|unclassified Bacteria 2|Bacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 DYD1_k127_351282_0 926569.ANT_10070 9.41e-142 453.0 COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi 200795|Chloroflexi J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C DYD1_k127_351282_5 926569.ANT_10060 6.342e-29 118.0 COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi 200795|Chloroflexi J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 DYD1_k127_351282_1 926569.ANT_10050 6.846e-73 251.0 COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi 200795|Chloroflexi J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 DYD1_k127_351282_2 926550.CLDAP_04100 1.37e-68 239.0 COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi 200795|Chloroflexi J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 DYD1_k127_3515198_1 926550.CLDAP_25550 2.02e-52 208.0 COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,2G8PE@200795|Chloroflexi 200795|Chloroflexi T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 DYD1_k127_3515198_0 1382306.JNIM01000001_gene1045 7.174e-68 238.0 COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi 200795|Chloroflexi K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg DYD1_k127_3515198_4 1906.SFRA_26615 1.167e-19 90.0 COG1553@1|root,COG1553@2|Bacteria,2IRB2@201174|Actinobacteria 201174|Actinobacteria P DsrE/DsrF-like family - - - ko:K06039 - - - - ko00000 - - - DrsE DYD1_k127_3515198_6 1255043.TVNIR_1704 0.000703 42.0 COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,1S809@1236|Gammaproteobacteria,1WZQ6@135613|Chromatiales 135613|Chromatiales P DsrE/DsrF-like family - - - ko:K06039 - - - - ko00000 - - - DrsE DYD1_k127_3515198_5 926550.CLDAP_18140 0.000133 53.0 COG3381@1|root,COG3381@2|Bacteria 2|Bacteria S protein complex oligomerization - - - - - - - - - - - - Nitrate_red_del DYD1_k127_3515198_2 589924.Ferp_1757 1.385e-44 167.0 COG0599@1|root,arCOG02148@2157|Archaea 2157|Archaea S PFAM Carboxymuconolactone decarboxylase - - - - - - - - - - - - CMD DYD1_k127_3515198_3 589924.Ferp_1759 4.873e-30 126.0 COG1765@1|root,arCOG03686@2157|Archaea,2XYGU@28890|Euryarchaeota 28890|Euryarchaeota O redox protein, regulator of disulfide bond formation - - - - - - - - - - - - OsmC DYD1_k127_3550676_3 926550.CLDAP_24610 3.498e-138 449.0 COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT DYD1_k127_3550676_4 1167006.UWK_00832 1.309e-69 244.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MJE6@213118|Desulfobacterales 28221|Deltaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA DYD1_k127_3550676_9 1206735.BAGG01000093_gene3816 9.569e-10 71.0 COG0226@1|root,COG0226@2|Bacteria,2GNPB@201174|Actinobacteria,4FY36@85025|Nocardiaceae 201174|Actinobacteria P PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 DYD1_k127_3550676_5 649638.Trad_0407 3.904e-52 201.0 COG0491@1|root,COG0491@2|Bacteria,1WIMP@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - - - - - - - - - - Lactamase_B DYD1_k127_3550676_1 1174528.JH992892_gene6439 8.787e-201 639.0 COG3033@1|root,COG3033@2|Bacteria,1G33V@1117|Cyanobacteria 1117|Cyanobacteria E Beta-eliminating lyase - - - - - - - - - - - - Beta_elim_lyase DYD1_k127_3550676_0 926550.CLDAP_23290 1.919e-217 689.0 COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi 200795|Chloroflexi V ABC transporter, transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_3550676_6 357808.RoseRS_2270 1.122e-47 179.0 COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia 32061|Chloroflexia V PFAM ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran DYD1_k127_3550676_2 316274.Haur_0218 3.624e-164 524.0 COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia 200795|Chloroflexi V PFAM ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran DYD1_k127_3550676_7 713586.KB900536_gene328 2.447e-27 117.0 COG2133@1|root,COG2133@2|Bacteria,1QWB2@1224|Proteobacteria 1224|Proteobacteria G CHRD domain - - - - - - - - - - - - CHRD DYD1_k127_3550676_8 420324.KI911932_gene321 3.634e-16 82.0 COG3899@1|root,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,1JR57@119045|Methylobacteriaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,SAM_1 DYD1_k127_3557832_6 926560.KE387025_gene3980 1.906e-90 308.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity devC - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_3557832_25 1089553.Tph_c20660 6.23e-07 55.0 2EPM3@1|root,33H7R@2|Bacteria,1VN2P@1239|Firmicutes,24WDX@186801|Clostridia,42IZ0@68295|Thermoanaerobacterales 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_3557832_0 635013.TherJR_2241 0.0 1049.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,2608V@186807|Peptococcaceae 186801|Clostridia P ATPase, P-type (transporting), HAD superfamily, subfamily IC copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase DYD1_k127_3557832_14 926560.KE387025_gene3987 4.02e-37 151.0 COG0785@1|root,COG0785@2|Bacteria,1WIZH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O PFAM cytochrome c biogenesis protein, transmembrane region - - - - - - - - - - - - DsbD DYD1_k127_3557832_16 670487.Ocepr_0483 6.452e-28 121.0 COG3794@1|root,COG3794@2|Bacteria 2|Bacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - Cupredoxin_1 DYD1_k127_3557832_1 472759.Nhal_2157 1.065e-275 865.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WVXM@135613|Chromatiales 135613|Chromatiales P heavy metal translocating P-type ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase DYD1_k127_3557832_17 644966.Tmar_1592 2.735e-25 115.0 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - - - - - - - - - - DUF5069,Lactamase_B,Rhodanese DYD1_k127_3557832_28 1095769.CAHF01000009_gene1376 0.0008684 44.0 COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria 1224|Proteobacteria S Ribonuclease, BN rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB DYD1_k127_3557832_27 1227497.C491_10654 8.034e-05 55.0 COG2217@1|root,arCOG02764@1|root,arCOG01576@2157|Archaea,arCOG02764@2157|Archaea,2XTD8@28890|Euryarchaeota,23SNP@183963|Halobacteria 183963|Halobacteria P COG2217 Cation transport ATPase - - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase DYD1_k127_3557832_12 309801.trd_A0787 1.086e-52 195.0 COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi,27XSN@189775|Thermomicrobia 189775|Thermomicrobia M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD1_k127_3557832_15 861299.J421_2831 1.341e-33 140.0 COG0785@1|root,COG0785@2|Bacteria,1ZTJC@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Cytochrome C biogenesis protein transmembrane region - - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD DYD1_k127_3557832_26 365044.Pnap_1257 1.579e-06 59.0 2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3557832_24 589924.Ferp_0793 3.559e-07 58.0 28WAT@1|root,2N56W@2157|Archaea,2Y40V@28890|Euryarchaeota,2476C@183980|Archaeoglobi 183980|Archaeoglobi - - - - - - - - - - - - - - - DYD1_k127_3557832_11 153948.NAL212_0227 7.735e-53 194.0 COG0500@1|root,COG2226@2|Bacteria,1PE85@1224|Proteobacteria,2W92M@28216|Betaproteobacteria,373FB@32003|Nitrosomonadales 28216|Betaproteobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_25 DYD1_k127_3557832_22 401053.AciPR4_0847 1.169e-08 67.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - ko:K07114,ko:K12511 - - - - ko00000,ko02000,ko02044 1.A.13.2.2,1.A.13.2.3 - - FHA,VWA,VWA_2 DYD1_k127_3557832_21 1489678.RDMS_08090 9.326e-12 75.0 COG1716@1|root,COG1716@2|Bacteria,1WMK0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T ATPase activity - - - - - - - - - - - - FHA,Yop-YscD_cpl DYD1_k127_3557832_18 530564.Psta_4147 8.197e-25 113.0 COG1310@1|root,COG1310@2|Bacteria 2|Bacteria S proteolysis - - - ko:K03665 - - - - ko00000,ko03009 - - - JAB,Prok-JAB DYD1_k127_3557832_20 886293.Sinac_1733 5.866e-12 69.0 2EFHE@1|root,3399Z@2|Bacteria,2J10E@203682|Planctomycetes 203682|Planctomycetes S WXG100 protein secretion system (Wss), protein YukD - - - - - - - - - - - - YukD DYD1_k127_3557832_13 326424.FRAAL0854 6.752e-40 162.0 COG5078@1|root,COG5078@2|Bacteria 2|Bacteria O protein modification by small protein conjugation - - - - - - - - - - - - ThiF,UQ_con,Yop-YscD_cpl DYD1_k127_3557832_5 886293.Sinac_1731 4.172e-106 364.0 COG0476@1|root,COG0476@2|Bacteria,2IY9K@203682|Planctomycetes 203682|Planctomycetes H PFAM UBA THIF-type NAD FAD binding protein - - - - - - - - - - - - ThiF DYD1_k127_3557832_7 525904.Tter_1915 1.686e-82 287.0 28NWQ@1|root,2ZBUI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3557832_2 926569.ANT_22760 1.244e-128 433.0 COG2223@1|root,COG2223@2|Bacteria 2|Bacteria P nitrite transmembrane transporter activity - - - ko:K02532 - - - - ko00000,ko02000 2.A.1.5 - - MFS_1 DYD1_k127_3557832_3 525904.Tter_2663 1.235e-126 417.0 COG2059@1|root,COG2059@2|Bacteria,2NPUT@2323|unclassified Bacteria 2|Bacteria P Chromate transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD1_k127_3557832_9 338969.Rfer_0357 1.818e-70 241.0 COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,4ABCM@80864|Comamonadaceae 28216|Betaproteobacteria P Chromate resistance exported protein - - - - - - - - - - - - Chrome_Resist DYD1_k127_3557832_8 404589.Anae109_1635 2.122e-79 280.0 COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,42PR8@68525|delta/epsilon subdivisions,2WK8J@28221|Deltaproteobacteria 28221|Deltaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_3557832_4 1048834.TC41_0187 1.302e-122 405.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli 91061|Bacilli I Belongs to the thiolase family - - - - - - - - - - - - Thiolase_C,Thiolase_N DYD1_k127_3557832_10 886293.Sinac_6000 1.625e-64 230.0 COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes 203682|Planctomycetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - 3.5.1.6 ko:K01431 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R00905,R04666,R08228 RC00096 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase DYD1_k127_3557832_19 744980.TRICHSKD4_4678 2.286e-22 98.0 29DWE@1|root,300UA@2|Bacteria,1RDK5@1224|Proteobacteria,2TY0U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cytochrome P460 - - - - - - - - - - - - Cytochrome_P460 DYD1_k127_3568352_12 326427.Cagg_1408 7.511e-08 62.0 COG3409@1|root,COG4946@1|root,COG3409@2|Bacteria,COG4946@2|Bacteria,2GBJ6@200795|Chloroflexi,377JA@32061|Chloroflexia 32061|Chloroflexia M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 DYD1_k127_3568352_11 1144343.PMI41_04648 3.332e-11 68.0 28ZXA@1|root,2ZMMS@2|Bacteria,1P6I7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_3568352_7 313596.RB2501_04065 7.026e-34 136.0 2CWCM@1|root,32SZF@2|Bacteria,4NSAZ@976|Bacteroidetes,1I2Z7@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4260) - - - - - - - - - - - - DUF4260 DYD1_k127_3568352_1 118166.JH976537_gene386 1.695e-122 408.0 COG0477@1|root,COG2814@2|Bacteria,1GQ8C@1117|Cyanobacteria,1HH9P@1150|Oscillatoriales 1117|Cyanobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_3568352_13 1236976.JCM16418_1913 4.565e-07 60.0 COG0657@1|root,COG0657@2|Bacteria,1UJ9C@1239|Firmicutes,4IV2R@91061|Bacilli,277T3@186822|Paenibacillaceae 91061|Bacilli I acetylesterase activity - - - - - - - - - - - - - DYD1_k127_3568352_4 926569.ANT_03600 5.579e-40 156.0 COG1225@1|root,COG1225@2|Bacteria,2G9KJ@200795|Chloroflexi 200795|Chloroflexi O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA DYD1_k127_3568352_5 926550.CLDAP_17030 5.552e-38 163.0 COG0823@1|root,COG0823@2|Bacteria,2G8W2@200795|Chloroflexi 200795|Chloroflexi U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - Big_5,PD40 DYD1_k127_3568352_2 926569.ANT_14150 2.239e-97 340.0 COG0449@1|root,COG0449@2|Bacteria 2|Bacteria M glutamine-fructose-6-phosphate transaminase (isomerizing) activity - - 2.6.1.16,5.3.1.8,5.3.1.9 ko:K00820,ko:K15916 ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931 M00001,M00004,M00114 R00768,R01819,R02739,R02740,R03321 RC00010,RC00163,RC00376,RC00563,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - SIS DYD1_k127_3568352_3 1173029.JH980292_gene4060 1.08e-80 278.0 COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,1H7AW@1150|Oscillatoriales 1117|Cyanobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase DYD1_k127_3568352_8 479431.Namu_2053 2.468e-20 94.0 COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4ETDM@85013|Frankiales 201174|Actinobacteria K Cold shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD1_k127_3568352_0 926569.ANT_11950 7.579e-240 757.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi 200795|Chloroflexi H Homocysteine S-methyltransferase - - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,S-methyl_trans DYD1_k127_3568352_6 266117.Rxyl_2043 7.187e-38 164.0 COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria 84995|Rubrobacteria H Transcriptional coactivator pterin dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a DYD1_k127_3568352_9 383372.Rcas_3011 4.331e-14 72.0 COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,37527@32061|Chloroflexia 32061|Chloroflexia J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g DYD1_k127_3578706_32 926561.KB900622_gene463 5.124e-21 107.0 29X3G@1|root,30IS5@2|Bacteria,1W5BE@1239|Firmicutes,24MZE@186801|Clostridia 186801|Clostridia S Protein of unknown function (DUF3795) - - - - - - - - - - - - DUF3795 DYD1_k127_3578706_28 118161.KB235922_gene2272 7.606e-27 115.0 COG3153@1|root,COG3153@2|Bacteria,1G9FX@1117|Cyanobacteria 1117|Cyanobacteria S acetyltransferase - - - - - - - - - - - - Acetyltransf_7 DYD1_k127_3578706_12 1382356.JQMP01000003_gene2139 2.089e-89 306.0 COG0686@1|root,COG0686@2|Bacteria,2G68X@200795|Chloroflexi,27YU4@189775|Thermomicrobia 189775|Thermomicrobia C Alanine dehydrogenase/PNT, N-terminal domain - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N DYD1_k127_3578706_2 751945.Theos_1594 6.985e-158 516.0 COG0427@1|root,COG0427@2|Bacteria,1WJIT@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Acetyl-CoA hydrolase/transferase C-terminal domain - - - - - - - - - - - - AcetylCoA_hyd_C,AcetylCoA_hydro DYD1_k127_3578706_21 1118054.CAGW01000053_gene1415 1.504e-55 205.0 COG0697@1|root,COG0697@2|Bacteria,1UH2I@1239|Firmicutes,4HCFV@91061|Bacilli,26TFQ@186822|Paenibacillaceae 91061|Bacilli EG membrane gmT1 - - - - - - - - - - - EamA DYD1_k127_3578706_5 1521187.JPIM01000100_gene107 1.646e-140 456.0 COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia 32061|Chloroflexia C PFAM thiamine pyrophosphate protein domain protein TPP-binding - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C DYD1_k127_3578706_1 525904.Tter_0334 2.39e-238 754.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria 2|Bacteria C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N DYD1_k127_3578706_20 926569.ANT_18160 1.211e-59 217.0 COG2186@1|root,COG2186@2|Bacteria,2G8XU@200795|Chloroflexi 200795|Chloroflexi K FCD domain - - - - - - - - - - - - FCD DYD1_k127_3578706_22 926569.ANT_10900 4.893e-41 161.0 COG2949@1|root,COG2949@2|Bacteria,2G6VI@200795|Chloroflexi 200795|Chloroflexi S DUF218 domain - - - - - - - - - - - - DUF218 DYD1_k127_3578706_16 926569.ANT_10890 4.171e-74 257.0 COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM metal dependent phophohydrolase - - - - - - - - - - - - HD DYD1_k127_3578706_13 926569.ANT_17240 3.017e-87 303.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - Glyco_hydro_18,LysM,PG_binding_1,SH3_3 DYD1_k127_3578706_7 1521187.JPIM01000065_gene1259 8.353e-118 387.0 COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,374VR@32061|Chloroflexia 32061|Chloroflexia C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N DYD1_k127_3578706_9 926569.ANT_09430 4.204e-108 359.0 COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi 200795|Chloroflexi H Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C DYD1_k127_3578706_6 1227739.Hsw_4060 2.123e-136 447.0 COG0659@1|root,COG0659@2|Bacteria 2|Bacteria P secondary active sulfate transmembrane transporter activity - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - MFS_MOT1 DYD1_k127_3578706_18 926569.ANT_18170 9.2e-61 227.0 COG0614@1|root,COG0614@2|Bacteria,2G8ZP@200795|Chloroflexi 200795|Chloroflexi P PFAM periplasmic binding protein - - - - - - - - - - - - Peripla_BP_2 DYD1_k127_3578706_19 383372.Rcas_1525 6.496e-60 214.0 COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,375NK@32061|Chloroflexia 32061|Chloroflexia S PFAM LmbE family protein - - - - - - - - - - - - PIG-L DYD1_k127_3578706_11 926569.ANT_18190 6.677e-95 319.0 COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi 200795|Chloroflexi NU PFAM PSP1 domain protein - - - - - - - - - - - - PSP1 DYD1_k127_3578706_3 926569.ANT_18200 4.743e-150 482.0 COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi 200795|Chloroflexi D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA DYD1_k127_3578706_26 926569.ANT_18210 4.312e-28 121.0 2FKJC@1|root,34C6D@2|Bacteria,2G9T3@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_3578706_14 926569.ANT_18220 2.474e-85 288.0 COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - 1.6.5.3 ko:K00338,ko:K03615 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 DYD1_k127_3578706_0 926569.ANT_18230 5.262e-283 880.0 COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5JF@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa DYD1_k127_3578706_10 926569.ANT_18240 2.128e-100 331.0 COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 DYD1_k127_3578706_31 1489678.RDMS_06070 3.546e-21 101.0 COG2345@1|root,COG2345@2|Bacteria,1WKAN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K transcriptional regulator - - - - - - - - - - - - HTH_11,HTH_20,HTH_5,MarR_2,TrmB DYD1_k127_3578706_23 309801.trd_1553 1.672e-35 139.0 COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi,27YEW@189775|Thermomicrobia 189775|Thermomicrobia S Belongs to the HesB IscA family - - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn DYD1_k127_3578706_27 1128421.JAGA01000003_gene3515 1.323e-27 119.0 COG4911@1|root,COG4911@2|Bacteria,2NQ4H@2323|unclassified Bacteria 2|Bacteria S Uncharacterized conserved protein (DUF2203) - - - - - - - - - - - - DUF2203 DYD1_k127_3578706_24 926569.ANT_18580 3.447e-35 142.0 COG3103@1|root,COG4991@2|Bacteria 2|Bacteria T sh3 domain protein - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - SH3_3 DYD1_k127_3578706_34 485913.Krac_0943 2.583e-08 63.0 2DRCD@1|root,33B7A@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3578706_15 326427.Cagg_0460 3.603e-82 279.0 COG0491@1|root,COG0491@2|Bacteria,2G8K6@200795|Chloroflexi,377BH@32061|Chloroflexia 32061|Chloroflexia S PFAM beta-lactamase domain protein - - - - - - - - - - - - Lactamase_B DYD1_k127_3578706_17 926569.ANT_04520 3.146e-69 239.0 COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi 200795|Chloroflexi C Pyruvate ferredoxin/flavodoxin oxidoreductase porG - 1.2.7.1,1.2.7.3 ko:K00172,ko:K00177 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00307,M00374,M00620 R01196,R01197,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR DYD1_k127_3578706_8 926569.ANT_04510 5.784e-115 376.0 COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi 200795|Chloroflexi C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C DYD1_k127_3578706_4 926569.ANT_04500 7.312e-147 473.0 COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi 200795|Chloroflexi C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N DYD1_k127_3578706_29 926569.ANT_04490 7.363e-25 107.0 COG1146@1|root,COG1146@2|Bacteria,2G7ES@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - 1.2.7.3 ko:K00176 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 M00009,M00011,M00173,M00620 R01197 RC00004,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4 DYD1_k127_3587384_2 1337093.MBE-LCI_2753 7.025e-10 64.0 COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,2U8SB@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Sigma 54 modulation protein / S30EA ribosomal protein - - - - - - - - - - - - CSD,Ribosomal_S30AE DYD1_k127_3587384_0 1123354.AUDR01000015_gene350 2.605e-209 661.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,1KRE8@119069|Hydrogenophilales 119069|Hydrogenophilales S tRNA-splicing ligase RtcB - - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB DYD1_k127_3587384_1 338969.Rfer_3853 1.273e-46 172.0 COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,2VU90@28216|Betaproteobacteria 28216|Betaproteobacteria S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease DYD1_k127_3589209_10 926569.ANT_07720 3.02e-12 68.0 COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi 200795|Chloroflexi P Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_3589209_4 926569.ANT_07730 4.537e-105 360.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - DUF11,DUF4114,DUF4157 DYD1_k127_3589209_3 926569.ANT_07740 1.585e-132 439.0 COG0577@1|root,COG0577@2|Bacteria,2G6MK@200795|Chloroflexi 200795|Chloroflexi V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_3589209_7 292459.STH2670 1.741e-39 169.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia 2|Bacteria L snf2 family - - - - - - - - - - - - Helicase_C,SNF2_N DYD1_k127_3589209_8 945713.IALB_1876 2.569e-21 101.0 2E03I@1|root,32VSC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3589209_1 926569.ANT_10550 9.077e-175 562.0 COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi 200795|Chloroflexi M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_3589209_5 926569.ANT_10540 9.175e-70 244.0 COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi 200795|Chloroflexi C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B DYD1_k127_3589209_9 243164.DET0559 1.68e-20 93.0 COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi,34DHU@301297|Dehalococcoidia 301297|Dehalococcoidia C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C DYD1_k127_3589209_6 926569.ANT_10520 8.896e-53 203.0 COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi 200795|Chloroflexi C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A DYD1_k127_3589209_2 926569.ANT_10480 2.076e-142 466.0 COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M DYD1_k127_3589209_0 926569.ANT_10470 2.996e-197 626.0 COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi 200795|Chloroflexi C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M DYD1_k127_3589372_20 696281.Desru_2664 1.161e-05 58.0 COG0823@1|root,COG0823@2|Bacteria,1VJYQ@1239|Firmicutes,24TCB@186801|Clostridia,262QX@186807|Peptococcaceae 186801|Clostridia U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 DYD1_k127_3589372_17 1210884.HG799474_gene15133 9.321e-16 89.0 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - CHU_C,VCBS DYD1_k127_3589372_5 1144275.COCOR_03289 5.102e-110 383.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria 1224|Proteobacteria IQ COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C,Acyl_transf_1,Bac_luciferase,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt DYD1_k127_3589372_19 1445613.JALM01000034_gene5196 1.012e-06 54.0 COG0236@1|root,COG0236@2|Bacteria,2GQKS@201174|Actinobacteria,4E75M@85010|Pseudonocardiales 201174|Actinobacteria IQ Phosphopantetheine attachment site - - - ko:K16025 ko01051,ko01052,map01051,map01052 - - - ko00000,ko00001 - - - PP-binding DYD1_k127_3589372_8 1120971.AUCA01000001_gene1761 1.016e-51 201.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,278S2@186823|Alicyclobacillaceae 91061|Bacilli M MBOAT, membrane-bound O-acyltransferase family - - - - - - - - - - - - MBOAT DYD1_k127_3589372_3 1476876.JOJO01000012_gene4155 1.392e-115 381.0 COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria 201174|Actinobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 DYD1_k127_3589372_15 1476876.JOJO01000012_gene4156 1.905e-27 129.0 COG0842@1|root,COG0842@2|Bacteria,2HDDD@201174|Actinobacteria 201174|Actinobacteria V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD1_k127_3589372_12 1536769.P40081_13810 8.982e-38 152.0 COG0842@1|root,COG0842@2|Bacteria,1V13R@1239|Firmicutes,4HD1H@91061|Bacilli,26U7M@186822|Paenibacillaceae 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD1_k127_3589372_11 671143.DAMO_2398 3.084e-41 156.0 2CP7W@1|root,32MRP@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3589372_16 269797.Mbar_A3137 2.895e-18 91.0 arCOG05215@1|root,arCOG05215@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - DYD1_k127_3589372_7 643648.Slip_1333 3.101e-58 211.0 COG2020@1|root,COG2020@2|Bacteria,1V0PB@1239|Firmicutes,24AQ6@186801|Clostridia 186801|Clostridia O Isoprenylcysteine carboxyl methyltransferase - - - - - - - - - - - - ICMT,PEMT DYD1_k127_3589372_2 926569.ANT_12630 4.663e-125 410.0 COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi 200795|Chloroflexi F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N DYD1_k127_3589372_6 326427.Cagg_0586 6.031e-86 301.0 COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi,3751X@32061|Chloroflexia 32061|Chloroflexia E TIGRFAM LAO AO transport system ATPase - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK DYD1_k127_3589372_9 926569.ANT_12670 4.56e-51 190.0 COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi 200795|Chloroflexi I PFAM cobalamin B12-binding domain protein - - 5.4.99.2 ko:K01849 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding DYD1_k127_3589372_18 926569.ANT_25610 6.142e-09 68.0 COG4254@1|root,COG4254@2|Bacteria,2G9J2@200795|Chloroflexi 200795|Chloroflexi M FecR protein - - - - - - - - - - - - FecR DYD1_k127_3589372_1 665571.STHERM_c14270 3.465e-145 477.0 COG0180@1|root,COG0180@2|Bacteria,2J68U@203691|Spirochaetes 203691|Spirochaetes J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b DYD1_k127_3589372_13 1122130.AUHN01000004_gene1177 9.528e-31 124.0 COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria 201174|Actinobacteria O belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_3589372_4 926569.ANT_25070 7.207e-111 368.0 COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi 200795|Chloroflexi K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA DYD1_k127_3589372_10 926569.ANT_25060 5.498e-42 162.0 COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi 200795|Chloroflexi O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE DYD1_k127_3589372_0 926569.ANT_25050 9.79e-299 929.0 COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi 200795|Chloroflexi O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD1_k127_359267_5 926569.ANT_02910 7.312e-16 79.0 COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - - - - - - - - - - Thy1 DYD1_k127_359267_2 751945.Theos_0407 1.823e-44 165.0 COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O redox protein regulator of disulfide bond formation osmC - - ko:K04063 - - - - ko00000 - - - OsmC DYD1_k127_359267_3 357808.RoseRS_4071 5.049e-38 154.0 COG3346@1|root,COG3346@2|Bacteria,2G8X9@200795|Chloroflexi,377E5@32061|Chloroflexia 32061|Chloroflexia S SURF1 family - - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 DYD1_k127_359267_0 1041930.Mtc_1172 4.22e-124 405.0 COG0863@1|root,arCOG00115@2157|Archaea,2XT30@28890|Euryarchaeota,2NAWJ@224756|Methanomicrobia 224756|Methanomicrobia L to Modification methylase in Methanococcus jannaschii (Q58392) and Methanobacterium thermoformicicum (P29568) - - 2.1.1.113,2.1.1.72 ko:K00571,ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase DYD1_k127_359267_1 926569.ANT_01460 2.606e-103 346.0 COG1159@1|root,COG1159@2|Bacteria,2G69C@200795|Chloroflexi 200795|Chloroflexi S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 DYD1_k127_359267_4 326427.Cagg_2634 4.263e-22 100.0 COG4454@1|root,COG4454@2|Bacteria 2|Bacteria - - - GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 ko:K00368,ko:K18683 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cupredoxin_1,SoxE DYD1_k127_3600690_7 561175.KB894098_gene5452 8.924e-78 272.0 COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4EIDG@85012|Streptosporangiales 201174|Actinobacteria O XdhC Rossmann domain - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI DYD1_k127_3600690_13 1297570.MESS4_210028 2.368e-45 175.0 2DV6Q@1|root,32UYT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3600690_6 525904.Tter_2279 2.045e-84 295.0 COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria 2|Bacteria C TIGRFAM geranylgeranyl reductase - - 1.3.99.38 ko:K21401 - - - - ko00000,ko01000 - - - FAD_binding_3 DYD1_k127_3600690_1 643473.KB235930_gene3594 2.494e-101 336.0 COG1562@1|root,COG1562@2|Bacteria,1G0U6@1117|Cyanobacteria,1HIMH@1161|Nostocales 1117|Cyanobacteria I PFAM Squalene phytoene synthase - - 2.5.1.21 ko:K00801 ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130 - R00702,R02872,R06223 RC00362,RC00796,RC02839 ko00000,ko00001,ko01000,ko01006 - - - SQS_PSY DYD1_k127_3600690_9 1434325.AZQN01000001_gene483 4.494e-60 216.0 COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,47J8W@768503|Cytophagia 976|Bacteroidetes S TIGRFAM TIGR02453 family protein - - - - - - - - - - - - DUF2461 DYD1_k127_3600690_2 867903.ThesuDRAFT_00836 3.344e-98 334.0 COG0446@1|root,COG0446@2|Bacteria,1UC47@1239|Firmicutes,24NN7@186801|Clostridia 186801|Clostridia S PFAM Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_3600690_11 926569.ANT_31280 4.539e-55 198.0 COG4087@1|root,COG4087@2|Bacteria,2G99M@200795|Chloroflexi 200795|Chloroflexi S Haloacid dehalogenase domain protein hydrolase - - - - - - - - - - - - Hydrolase_3 DYD1_k127_3600690_15 926569.ANT_31270 1.235e-37 158.0 COG1808@1|root,COG1808@2|Bacteria 2|Bacteria S Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 DYD1_k127_3600690_10 926569.ANT_20960 6.224e-60 220.0 COG0803@1|root,COG0803@2|Bacteria,2G6XK@200795|Chloroflexi 200795|Chloroflexi P Zinc-uptake complex component A periplasmic - - - ko:K09818 - M00243 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA DYD1_k127_3600690_5 926569.ANT_20970 6.92e-88 298.0 COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi 200795|Chloroflexi P PFAM ABC transporter related - - - ko:K09820,ko:K11710 ko02010,map02010 M00243,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC_tran DYD1_k127_3600690_4 383372.Rcas_1589 4.585e-88 303.0 COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,376AB@32061|Chloroflexia 32061|Chloroflexia P ABC-3 protein - - - ko:K09819 - M00243 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 DYD1_k127_3600690_14 525904.Tter_1099 4.765e-42 177.0 COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - - DYD1_k127_3600690_3 926569.ANT_04130 2.86e-91 321.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi 200795|Chloroflexi T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,GAF_3,HATPase_c,HisKA_3 DYD1_k127_3600690_8 479434.Sthe_2059 8.971e-63 229.0 COG0644@1|root,COG0644@2|Bacteria,2G8CW@200795|Chloroflexi,27XII@189775|Thermomicrobia 189775|Thermomicrobia C FAD binding domain - - - - - - - - - - - - FAD_binding_3 DYD1_k127_3600690_0 926550.CLDAP_17570 1.413e-117 385.0 COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi 200795|Chloroflexi C FAD-dependent pyridine nucleotide-disulphide oxidoreductase trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_3600690_12 324602.Caur_3164 3.441e-53 203.0 COG2267@1|root,COG2267@2|Bacteria,2G6W2@200795|Chloroflexi 200795|Chloroflexi I PFAM alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6 DYD1_k127_360668_2 357808.RoseRS_4146 1.292e-128 422.0 COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,374Z5@32061|Chloroflexia 32061|Chloroflexia C PFAM acyl-CoA dehydrogenase domain protein - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_360668_3 926569.ANT_01960 4.652e-29 119.0 COG0721@1|root,COG0721@2|Bacteria 2|Bacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - iAF987.Gmet_0076 Glu-tRNAGln DYD1_k127_360668_0 926569.ANT_01950 1.028e-226 717.0 COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi 2|Bacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD1_k127_360668_4 1254432.SCE1572_02095 2.119e-13 72.0 COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,43DUN@68525|delta/epsilon subdivisions,2WYXG@28221|Deltaproteobacteria,2Z0V5@29|Myxococcales 28221|Deltaproteobacteria P Castor and Pollux, part of voltage-gated ion channel - - - - - - - - - - - - Castor_Poll_mid DYD1_k127_360668_1 1499967.BAYZ01000123_gene2540 5.002e-143 470.0 COG0064@1|root,COG0064@2|Bacteria,2NNPK@2323|unclassified Bacteria 2|Bacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 ko:K01876,ko:K02434 ko00970,ko01100,map00970,map01100 M00359,M00360 R03905,R04212,R05577 RC00010,RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GatB_N,GatB_Yqey DYD1_k127_3609605_0 1254432.SCE1572_20255 3.319e-128 422.0 COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,42TEH@68525|delta/epsilon subdivisions,2WPV9@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_3609605_1 1254432.SCE1572_20250 5.931e-81 275.0 COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997,ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_3636089_1 671143.DAMO_0767 1.182e-27 117.0 COG0723@1|root,COG0723@2|Bacteria,2NRUZ@2323|unclassified Bacteria 2|Bacteria C Rieske [2Fe-2S] domain - - 1.10.9.1 ko:K02636,ko:K03886 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00151,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske DYD1_k127_3636089_0 644966.Tmar_0325 5.634e-50 186.0 COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,24K8U@186801|Clostridia 186801|Clostridia C Cytochrome b subunit of the bc - - - ko:K00412,ko:K02635 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrome_B DYD1_k127_3689291_2 926569.ANT_18370 3.098e-35 144.0 COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi 200795|Chloroflexi S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO DYD1_k127_3689291_0 926569.ANT_18380 3.567e-102 354.0 COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi 200795|Chloroflexi S oligosaccharyl transferase activity - - - - - - - - - - - - - DYD1_k127_3689291_1 926569.ANT_18390 2.488e-35 147.0 COG4485@1|root,COG4485@2|Bacteria,2G6VS@200795|Chloroflexi 200795|Chloroflexi S Bacterial membrane protein, YfhO - - - - - - - - - - - - - DYD1_k127_379387_10 1122138.AQUZ01000040_gene6209 1.558e-07 56.0 COG0346@1|root,COG0346@2|Bacteria,2IS4J@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase DYD1_k127_379387_0 926569.ANT_26670 1.156e-272 846.0 COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi 200795|Chloroflexi O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD1_k127_379387_5 926569.ANT_26660 7.915e-37 141.0 COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi 200795|Chloroflexi O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD1_k127_379387_2 926569.ANT_00860 4.256e-98 337.0 COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi 200795|Chloroflexi S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2 DYD1_k127_379387_3 926569.ANT_00870 1.035e-83 293.0 COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi 200795|Chloroflexi S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2 DYD1_k127_379387_4 926569.ANT_03890 1.02e-48 196.0 COG0457@1|root,COG0457@2|Bacteria 926569.ANT_03890|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_379387_6 926569.ANT_03880 6.742e-34 136.0 COG5615@1|root,COG5615@2|Bacteria 2|Bacteria L integral membrane protein - - - - - - - - - - - - CopD DYD1_k127_379387_1 926569.ANT_05010 1.417e-122 400.0 COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi 200795|Chloroflexi S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 DYD1_k127_379387_8 518766.Rmar_0721 1.228e-13 83.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - - DYD1_k127_379387_7 324602.Caur_3114 1.705e-31 132.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD1_k127_379387_9 1128421.JAGA01000003_gene2919 3.299e-10 72.0 2EMMB@1|root,33F9Q@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_379657_6 688269.Theth_1877 5.968e-48 179.0 COG2110@1|root,COG2110@2|Bacteria,2GD2K@200918|Thermotogae 200918|Thermotogae S PFAM Appr-1-p processing domain protein - - - - - - - - - - - - Macro DYD1_k127_379657_7 926569.ANT_26460 6.057e-48 184.0 COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi 200795|Chloroflexi J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family - - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind DYD1_k127_379657_4 926569.ANT_26470 7.269e-98 338.0 COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi 200795|Chloroflexi S Uncharacterised ACR (DUF711) - - - ko:K09157 - - - - ko00000 - - - DUF711 DYD1_k127_379657_1 311424.DhcVS_979 2.765e-199 648.0 COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia 301297|Dehalococcoidia L UvrD/REP helicase N-terminal domain pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD1_k127_379657_9 925409.KI911562_gene814 0.0006157 48.0 COG1807@1|root,COG1807@2|Bacteria,4NXH6@976|Bacteroidetes,1IVBY@117747|Sphingobacteriia 976|Bacteroidetes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - DYD1_k127_379657_2 326427.Cagg_0119 1.989e-118 390.0 COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi,3754S@32061|Chloroflexia 32061|Chloroflexia M Belongs to the NAD(P)-dependent epimerase dehydratase family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD1_k127_379657_5 335543.Sfum_0266 8.497e-65 229.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42PQM@68525|delta/epsilon subdivisions,2WJIF@28221|Deltaproteobacteria,2MRCK@213462|Syntrophobacterales 28221|Deltaproteobacteria Q ubiE/COQ5 methyltransferase family - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - HTH_20,Methyltransf_31 DYD1_k127_379657_8 485913.Krac_8211 2.127e-34 147.0 COG1595@1|root,COG1595@2|Bacteria,2G93G@200795|Chloroflexi 200795|Chloroflexi K RNA polymerase, sigma-24 subunit, ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_379657_0 926569.ANT_03940 4.326e-212 666.0 COG0538@1|root,COG0538@2|Bacteria,2G5SM@200795|Chloroflexi 200795|Chloroflexi C TIGRFAM isocitrate dehydrogenase, NADP-dependent - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - CBS,Iso_dh DYD1_k127_379657_3 1085623.GNIT_0042 5.004e-111 366.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,4640X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD1_k127_3836857_3 926569.ANT_12010 3.396e-46 171.0 COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi 200795|Chloroflexi J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 DYD1_k127_3836857_2 926569.ANT_12000 2.362e-109 367.0 COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi 200795|Chloroflexi C Metallopeptidase family M24 - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD1_k127_3836857_1 1382306.JNIM01000001_gene83 2.569e-141 463.0 COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi 200795|Chloroflexi H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA DYD1_k127_3836857_0 926569.ANT_00880 2.497e-177 577.0 COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi 200795|Chloroflexi S PFAM ABC transporter related - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn DYD1_k127_3839406_3 324602.Caur_1864 0.0009593 44.0 COG3023@1|root,COG4288@1|root,COG3023@2|Bacteria,COG4288@2|Bacteria,2G8VN@200795|Chloroflexi,375C9@32061|Chloroflexia 32061|Chloroflexia V PFAM N-acetylmuramoyl-L-alanine amidase, family 2 - - - - - - - - - - - - Amidase_2 DYD1_k127_3839406_2 42256.RradSPS_0743 5.092e-37 159.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - DUF2723,PMT_2 DYD1_k127_3839406_0 926569.ANT_07720 2.614e-81 284.0 COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi 200795|Chloroflexi P Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_3839844_2 316274.Haur_3362 9.072e-112 370.0 COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia 32061|Chloroflexia E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD1_k127_3839844_0 926569.ANT_30670 2.4e-288 905.0 COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi 200795|Chloroflexi O Heat shock 70 kDa protein - - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD1_k127_3839844_4 1125863.JAFN01000001_gene2311 2.373e-87 304.0 COG0215@1|root,COG0215@2|Bacteria 2|Bacteria J cysteine-tRNA ligase activity - - - - - - - - - - - - Peptidase_S51 DYD1_k127_3839844_8 1382356.JQMP01000003_gene1897 1.08e-47 177.0 COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia 189775|Thermomicrobia S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 DYD1_k127_3839844_9 926550.CLDAP_14450 4.081e-45 172.0 COG3815@1|root,COG3815@2|Bacteria 2|Bacteria S Predicted membrane protein (DUF2085) - - - - - - - - - - - - DUF2085 DYD1_k127_3839844_13 521011.Mpal_0132 9.148e-19 87.0 COG3350@1|root,arCOG04507@2157|Archaea,2Y15C@28890|Euryarchaeota 28890|Euryarchaeota S YHS domain - - - - - - - - - - - - YHS DYD1_k127_3839844_5 1128421.JAGA01000002_gene1308 6.715e-64 226.0 COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria 2|Bacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_3839844_7 1128421.JAGA01000002_gene1307 5.839e-49 195.0 COG4585@1|root,COG4585@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K07777 ko02020,map02020 M00478 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8 DYD1_k127_3839844_11 670487.Ocepr_0566 7.836e-33 138.0 COG3212@1|root,COG3212@2|Bacteria,1WJK6@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S peptidase - - - - - - - - - - - - - DYD1_k127_3839844_14 666686.B1NLA3E_08395 8.222e-16 84.0 298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,1ZH6F@1386|Bacillus 91061|Bacilli S Protein of unknown function with PCYCGC motif - - - - - - - - - - - - PCYCGC DYD1_k127_3839844_12 118005.AWNK01000010_gene335 4.091e-19 96.0 COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor vnfA - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding DYD1_k127_3839844_3 589924.Ferp_0126 2.094e-90 317.0 COG0348@1|root,arCOG02772@2157|Archaea,2Y7DD@28890|Euryarchaeota,246PC@183980|Archaeoglobi 183980|Archaeoglobi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4_5 DYD1_k127_3839844_17 118005.AWNK01000010_gene334 1.065e-08 68.0 COG4633@1|root,COG4633@2|Bacteria 2|Bacteria - - silP - 1.9.3.1,3.6.3.54 ko:K02275,ko:K17686 ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016 M00155 R00081,R00086 RC00002,RC00016 ko00000,ko00001,ko00002,ko01000 3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6 - - Cupredoxin_1,DsbD_2,HMA DYD1_k127_3839844_18 1123377.AUIV01000006_gene1513 5.306e-07 62.0 COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria,1X4W4@135614|Xanthomonadales 135614|Xanthomonadales P Iron permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - Cytochrome_CBB3,FTR1 DYD1_k127_3839844_19 56780.SYN_02429 2.435e-05 51.0 COG3462@1|root,COG3462@2|Bacteria,1Q55M@1224|Proteobacteria,42WZ8@68525|delta/epsilon subdivisions,2WSP8@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Short C-terminal domain - - - ko:K08982 - - - - ko00000 - - - SHOCT DYD1_k127_3839844_15 525904.Tter_2238 9.615e-16 83.0 COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2NPD2@2323|unclassified Bacteria 2|Bacteria Q Multicopper oxidase - GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.16.3.3,1.7.2.1 ko:K00368,ko:K18683,ko:K22348 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,DUF4396 DYD1_k127_3839844_6 926550.CLDAP_04380 1.925e-56 211.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi 200795|Chloroflexi M Peptidoglycan-binding LysM - - - - - - - - - - - - LysM,Peptidase_M23,SH3_3 DYD1_k127_3839844_16 635013.TherJR_2273 4.168e-09 67.0 29RA3@1|root,30CBN@2|Bacteria,1W5X6@1239|Firmicutes,25561@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_3839844_10 926550.CLDAP_40040 8.474e-42 161.0 COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi 200795|Chloroflexi CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,DnaJ DYD1_k127_3839844_1 525904.Tter_1507 7.887e-136 451.0 COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria 2|Bacteria O Cytochrome C assembly protein ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198,ko:K04016 - - R05712 RC00176 ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD1_k127_3841003_7 290397.Adeh_1439 3.489e-45 165.0 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria,2YUFW@29|Myxococcales 28221|Deltaproteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N,Glyco_hydro_2 DYD1_k127_3841003_3 671143.DAMO_0484 7.754e-96 327.0 COG0837@1|root,COG0837@2|Bacteria,2NR7Y@2323|unclassified Bacteria 2|Bacteria F Glucokinase glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase DYD1_k127_3841003_8 671143.DAMO_0621 2.057e-32 134.0 COG1452@1|root,COG1452@2|Bacteria 2|Bacteria M lipopolysaccharide transport - - - ko:K22110 - - - - ko00000,ko02000 1.B.35.1,1.B.35.2 - - Glyco_hydro_63 DYD1_k127_3841003_1 322710.Avin_44030 6.938e-159 520.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase DYD1_k127_3841003_0 1267534.KB906761_gene1195 0.0 1423.0 COG3957@1|root,COG3957@2|Bacteria,3Y3XU@57723|Acidobacteria,2JKSB@204432|Acidobacteriia 204432|Acidobacteriia G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N DYD1_k127_3841003_5 344747.PM8797T_23024 4.615e-72 264.0 COG0406@1|root,COG0406@2|Bacteria,2IZ7M@203682|Planctomycetes 203682|Planctomycetes G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 DYD1_k127_3841003_9 196490.AUEZ01000002_gene4236 9.044e-29 123.0 COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,2U10P@28211|Alphaproteobacteria,3JWNC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Transaldolase/Fructose-6-phosphate aldolase - - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA DYD1_k127_3841003_11 228410.NE2136 2.948e-10 64.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,371UZ@32003|Nitrosomonadales 28216|Betaproteobacteria H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2,5.3.1.9 ko:K00616,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA DYD1_k127_3841003_12 344747.PM8797T_23039 1.307e-08 60.0 COG0166@1|root,COG0166@2|Bacteria,2IXRA@203682|Planctomycetes 203682|Planctomycetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI DYD1_k127_3841003_2 497964.CfE428DRAFT_5577 3.619e-130 422.0 COG3588@1|root,COG3588@2|Bacteria 2|Bacteria G fructose-bisphosphate aldolase fda - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic DYD1_k127_3841003_4 869210.Marky_0919 1.089e-73 258.0 COG0036@1|root,COG0036@2|Bacteria,1WI8K@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Ribulose-phosphate 3 epimerase family - - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim DYD1_k127_3841003_6 1380386.JIAW01000003_gene442 2.575e-56 208.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,2364D@1762|Mycobacteriaceae 201174|Actinobacteria T PFAM Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,Guanylate_cyc DYD1_k127_3857659_2 926569.ANT_22530 2.65e-44 168.0 COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi 200795|Chloroflexi S Uncharacterized protein conserved in bacteria (DUF2344) - - - - - - - - - - - - DUF2344 DYD1_k127_3857659_0 926569.ANT_22520 3.072e-267 839.0 COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi 200795|Chloroflexi C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM DYD1_k127_3857659_4 457570.Nther_2240 0.000182 49.0 COG4968@1|root,COG4968@2|Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif - - - ko:K02456,ko:K02650 ko02020,ko03070,ko05111,map02020,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - N_methyl DYD1_k127_3857659_1 266117.Rxyl_1165 1.613e-113 379.0 COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria 84995|Rubrobacteria NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD1_k127_3857659_3 370438.PTH_1144 2.687e-17 83.0 COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,26256@186807|Peptococcaceae 186801|Clostridia NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 DYD1_k127_386357_2 926550.CLDAP_07690 1.6e-99 335.0 COG1131@1|root,COG1131@2|Bacteria,2G7U7@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_386357_1 926569.ANT_11200 1.547e-130 437.0 COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi 200795|Chloroflexi M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap DYD1_k127_386357_0 926569.ANT_11210 9.394e-155 506.0 COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi 200795|Chloroflexi E Formiminotransferase domain, N-terminal subdomain - - 2.1.2.5,4.3.1.4 ko:K00603,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 - R02287,R02302,R03189 RC00165,RC00221,RC00223,RC00688,RC00870 ko00000,ko00001,ko01000,ko03036,ko04147 - - - FTCD,FTCD_C,FTCD_N DYD1_k127_386357_3 552811.Dehly_1213 1.155e-63 233.0 COG2211@1|root,COG2211@2|Bacteria,2G8SN@200795|Chloroflexi 200795|Chloroflexi G PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - - DYD1_k127_3922811_1 1123367.C666_13010 2.162e-61 219.0 COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,2VREP@28216|Betaproteobacteria,2KWFI@206389|Rhodocyclales 206389|Rhodocyclales E branched-chain amino acid permease (azaleucine resistance) - - - - - - - - - - - - AzlC DYD1_k127_3922811_2 1033802.SSPSH_002651 1.438e-13 76.0 COG4392@1|root,COG4392@2|Bacteria,1NH6U@1224|Proteobacteria,1SGUY@1236|Gammaproteobacteria 1236|Gammaproteobacteria S branched-chain amino acid - - - - - - - - - - - - AzlD DYD1_k127_3922811_0 357808.RoseRS_1483 8.8e-111 372.0 COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,375BG@32061|Chloroflexia 32061|Chloroflexia P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer DYD1_k127_3954851_9 326427.Cagg_0218 1.311e-28 134.0 COG0823@1|root,COG0823@2|Bacteria,2G8T8@200795|Chloroflexi,377EP@32061|Chloroflexia 32061|Chloroflexia U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 DYD1_k127_3954851_3 1382356.JQMP01000001_gene1076 1.592e-86 316.0 COG0465@1|root,COG0465@2|Bacteria,2G5JA@200795|Chloroflexi,27YWY@189775|Thermomicrobia 189775|Thermomicrobia D Peptidase family M41 - - - - - - - - - - - - AAA,Peptidase_M41 DYD1_k127_3954851_10 324602.Caur_2531 7.912e-26 121.0 COG0793@1|root,COG0793@2|Bacteria,2GBRW@200795|Chloroflexi,376BR@32061|Chloroflexia 32061|Chloroflexia M PFAM PDZ DHR GLGF domain protein - - - - - - - - - - - - PDZ_2,Peptidase_S41,Tricorn_C1 DYD1_k127_3954851_13 644966.Tmar_0065 0.0005777 48.0 2EPNR@1|root,33H9C@2|Bacteria,1VN0S@1239|Firmicutes,24WKV@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_3954851_0 926569.ANT_14030 2.42e-303 944.0 COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi 200795|Chloroflexi J elongation factor Tu domain 2 protein - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_3954851_12 246197.MXAN_6156 3.588e-05 48.0 COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,2Z04N@29|Myxococcales 28221|Deltaproteobacteria CO Cytochrome C biogenesis protein transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD,Thioredoxin DYD1_k127_3954851_8 926569.ANT_10650 3.139e-30 133.0 COG0500@1|root,COG0500@2|Bacteria 2|Bacteria Q methyltransferase activity - - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - Methyltransf_25,TPMT DYD1_k127_3954851_4 926550.CLDAP_34250 2.893e-78 273.0 COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - - - - - - - - - - Metalloenzyme DYD1_k127_3954851_7 926569.ANT_04460 6.478e-35 139.0 COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi 200795|Chloroflexi S PFAM flavin reductase domain protein, FMN-binding - - - - - - - - - - - - Flavin_Reduct DYD1_k127_3954851_6 926569.ANT_04450 1.022e-49 183.0 COG2078@1|root,COG2078@2|Bacteria 2|Bacteria S ferrous iron binding - - - ko:K06990,ko:K09141 - - - - ko00000,ko04812 - - - AMMECR1,Memo DYD1_k127_3954851_1 1128421.JAGA01000002_gene1937 1.163e-91 320.0 COG0477@1|root,COG2814@2|Bacteria,2NS3M@2323|unclassified Bacteria 2|Bacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 DYD1_k127_3954851_11 867903.ThesuDRAFT_00431 1.82e-17 87.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,24N37@186801|Clostridia,3WDCC@538999|Clostridiales incertae sedis 186801|Clostridia S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec DYD1_k127_3954851_2 1121403.AUCV01000065_gene4170 6.905e-90 319.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2X5IZ@28221|Deltaproteobacteria,2MPF3@213118|Desulfobacterales 28221|Deltaproteobacteria P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger DYD1_k127_3954851_5 765910.MARPU_00280 1.406e-75 265.0 COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1WZAK@135613|Chromatiales 135613|Chromatiales U Involved in arsenical resistance. Thought to form the channel of an arsenite pump arsB - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB DYD1_k127_3998849_2 671143.DAMO_1613 7.891e-63 220.0 COG1143@1|root,COG1143@2|Bacteria,2NRUK@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S dicluster domain ndhI - 1.6.5.3 ko:K00338,ko:K05580 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 DYD1_k127_3998849_1 671143.DAMO_1614 1.696e-89 297.0 COG0377@1|root,COG0377@2|Bacteria,2NPEF@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 DYD1_k127_3998849_0 525904.Tter_0593 1.627e-106 358.0 COG1252@1|root,COG1252@2|Bacteria,2NP3T@2323|unclassified Bacteria 2|Bacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase ndh - 1.6.99.3 ko:K03885,ko:K15977 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_4050434_1 1041146.ATZB01000009_gene3597 1.279e-180 567.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria,4B7H1@82115|Rhizobiaceae 28211|Alphaproteobacteria F Dihydroorotase and related cyclic amidohydrolases dht - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 DYD1_k127_4050434_2 331869.BAL199_13563 3.499e-138 442.0 COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,4BT7U@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities tauB - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_4050434_4 1415756.JQMY01000001_gene3056 6.744e-128 414.0 COG0600@1|root,COG0600@2|Bacteria,1MUAR@1224|Proteobacteria,2TTED@28211|Alphaproteobacteria,2PDJT@252301|Oceanicola 28211|Alphaproteobacteria P ABC transporter permease - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_4050434_3 1231190.NA8A_05438 1.614e-136 456.0 COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSP5@28211|Alphaproteobacteria,43IS6@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_4050434_0 331869.BAL199_14462 2.114e-184 580.0 COG0715@1|root,COG0715@2|Bacteria,1MXA3@1224|Proteobacteria,2TQV6@28211|Alphaproteobacteria,4BPXG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P NMT1/THI5 like thiY - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_4050434_6 190650.CC_2880 1.308e-07 59.0 COG3668@1|root,COG3668@2|Bacteria 2|Bacteria D Plasmid stabilization system relE3 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - - - - - - - - - - ParE_toxin DYD1_k127_4050434_5 1002340.AFCF01000031_gene4131 6.963e-08 55.0 COG1357@1|root,COG1357@2|Bacteria,1RCEV@1224|Proteobacteria,2U636@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide_3 DYD1_k127_4061750_6 357808.RoseRS_0852 5.785e-11 75.0 COG1807@1|root,COG3063@1|root,COG1807@2|Bacteria,COG3063@2|Bacteria,2G9FD@200795|Chloroflexi 200795|Chloroflexi M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2,TPR_16,TPR_8 DYD1_k127_4061750_5 926569.ANT_17910 2.627e-89 302.0 COG2120@1|root,COG2120@2|Bacteria 2|Bacteria S N-acetylglucosaminylinositol deacetylase activity yaiS - - - - - - - - - - - PIG-L,Response_reg DYD1_k127_4061750_4 926569.ANT_17900 2.702e-108 362.0 COG0500@1|root,COG2226@2|Bacteria,2G78Q@200795|Chloroflexi 200795|Chloroflexi Q PFAM Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_4061750_1 926569.ANT_06480 5.133e-145 477.0 COG0381@1|root,COG0381@2|Bacteria 2|Bacteria M UDP-N-acetylglucosamine 2-epimerase activity - - - - - - - - - - - - - DYD1_k127_4061750_2 926569.ANT_06470 8.658e-142 455.0 COG2089@1|root,COG2089@2|Bacteria,2G8IV@200795|Chloroflexi 200795|Chloroflexi M NeuB family - - 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 - R01804,R04435 RC00159 ko00000,ko00001,ko01000 - - - NeuB DYD1_k127_4061750_0 926569.ANT_06460 1.161e-158 523.0 COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria 2|Bacteria S 3-deoxy-manno-octulosonate-8-phosphatase activity neuA - 2.7.7.43,3.1.3.45 ko:K00983,ko:K03270 ko00520,ko00540,ko01100,map00520,map00540,map01100 M00063 R01117,R03350,R04215 RC00017,RC00152 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3,Hydrolase_3 DYD1_k127_4061750_3 926569.ANT_06450 1.862e-108 357.0 COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi 200795|Chloroflexi IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 DYD1_k127_4079363_1 926569.ANT_06180 6.815e-125 415.0 COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - - - - - - - - - - LytR_C,LytR_cpsA_psr DYD1_k127_4079363_8 926569.ANT_03650 7.74e-44 165.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 - R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 - - - PAP2 DYD1_k127_4079363_7 926569.ANT_03640 3.228e-67 237.0 COG0746@1|root,COG0746@2|Bacteria 2|Bacteria H molybdenum cofactor guanylyltransferase activity mobA GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 ko:K03752,ko:K13818 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD1_k127_4079363_9 748280.NH8B_0120 6.199e-23 104.0 COG3695@1|root,COG3695@2|Bacteria,1PZ1M@1224|Proteobacteria,2W33J@28216|Betaproteobacteria,2KT3U@206351|Neisseriales 206351|Neisseriales H 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - ko:K07443 - - - - ko00000 - - - DNA_binding_1 DYD1_k127_4079363_4 926569.ANT_03630 7.047e-108 357.0 COG5322@1|root,COG5322@2|Bacteria,2G8N0@200795|Chloroflexi 200795|Chloroflexi S PFAM Shikimate quinate 5-dehydrogenase - - - - - - - - - - - - Shikimate_DH DYD1_k127_4079363_5 525904.Tter_0098 2.983e-105 360.0 COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria 2|Bacteria EGP Transmembrane secretion effector entS - - ko:K08225 - - - - ko00000,ko02000 2.A.1.38 - - MFS_1,MFS_3 DYD1_k127_4079363_2 926569.ANT_07770 2.119e-116 396.0 COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi 200795|Chloroflexi H NAD synthase - - 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase DYD1_k127_4079363_3 926569.ANT_07760 3.132e-111 367.0 COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase DYD1_k127_4079363_11 743525.TSC_c23080 1.987e-05 55.0 COG0682@1|root,COG0682@2|Bacteria,1WJCB@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD1_k127_4079363_6 1242864.D187_008025 4.435e-103 347.0 COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales 28221|Deltaproteobacteria K acetyltransferase - - - - - - - - - - - - - DYD1_k127_4079363_10 309801.trd_1267 5.792e-14 80.0 COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia 189775|Thermomicrobia O NfeD-like C-terminal, partner-binding - - - ko:K07403 - - - - ko00000 - - - NfeD DYD1_k127_4079363_0 926569.ANT_29010 1.492e-132 431.0 COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi 200795|Chloroflexi O PFAM band 7 protein - - - - - - - - - - - - Band_7 DYD1_k127_4092362_0 857293.CAAU_0151 4.67e-154 504.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,36F95@31979|Clostridiaceae 186801|Clostridia G solute-binding protein - - - - - - - - - - - - SBP_bac_8 DYD1_k127_4092362_1 926550.CLDAP_02930 7.101e-92 313.0 COG1609@1|root,COG1609@2|Bacteria,2G675@200795|Chloroflexi 200795|Chloroflexi K Periplasmic binding protein LacI transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 DYD1_k127_4092362_2 765420.OSCT_2228 2.081e-36 152.0 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - DUF3160,YARHG,zinc_ribbon_2 DYD1_k127_4099873_17 926569.ANT_09380 5.017e-18 96.0 28XMW@1|root,2ZJIW@2|Bacteria,2G9GS@200795|Chloroflexi 926569.ANT_09380|- - - - - - - - - - - - - - - - DYD1_k127_4099873_15 926569.ANT_09380 2.971e-22 108.0 28XMW@1|root,2ZJIW@2|Bacteria,2G9GS@200795|Chloroflexi 926569.ANT_09380|- - - - - - - - - - - - - - - - DYD1_k127_4099873_4 1128421.JAGA01000002_gene163 4.498e-119 392.0 COG1063@1|root,COG1063@2|Bacteria,2NPK3@2323|unclassified Bacteria 2|Bacteria E Zinc-binding dehydrogenase tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_4099873_3 926569.ANT_25020 3.461e-122 400.0 COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi 200795|Chloroflexi C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD1_k127_4099873_14 530564.Psta_0167 2.506e-26 125.0 COG3621@1|root,COG3621@2|Bacteria 2|Bacteria AT Patatin-like phospholipase - - - - - - - - - - - - Patatin DYD1_k127_4099873_1 926569.ANT_03590 1.03e-167 561.0 COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase, family 51 - - - - - - - - - - - - Transgly,Transpeptidase DYD1_k127_4099873_10 1191523.MROS_1542 5.021e-62 219.0 COG2193@1|root,COG2193@2|Bacteria 2|Bacteria P ferroxidase activity bfr GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin DYD1_k127_4099873_16 301.JNHE01000028_gene800 1.663e-20 98.0 COG3422@1|root,COG3422@2|Bacteria,1N0S6@1224|Proteobacteria,1SAWP@1236|Gammaproteobacteria,1YGHE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF1508) - - - ko:K09946 - - - - ko00000 - - - DUF1508 DYD1_k127_4099873_5 926569.ANT_29900 3.328e-115 382.0 COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi 200795|Chloroflexi S Putative pyruvate format-lyase activating enzyme (DUF1786) - - - - - - - - - - - - DUF1786 DYD1_k127_4099873_6 926569.ANT_22580 7.939e-97 342.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi 200795|Chloroflexi KLTU Protein tyrosine kinase - - - - - - - - - - - - PD40,Pkinase DYD1_k127_4099873_2 665577.JH993789_gene6977 1.226e-151 499.0 COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria 201174|Actinobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - 1.17.1.9,1.6.5.3 ko:K00122,ko:K00335 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB DYD1_k127_4099873_11 671143.DAMO_1601 4.042e-56 218.0 COG1526@1|root,COG1526@2|Bacteria,2NPF9@2323|unclassified Bacteria 2|Bacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ,NTP_transf_3 DYD1_k127_4099873_9 926550.CLDAP_05930 7.57e-85 287.0 COG3383@1|root,COG3383@2|Bacteria 2|Bacteria C formate dehydrogenase (NAD+) activity - - - - - - - - - - - - Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,cNMP_binding DYD1_k127_4099873_13 670487.Ocepr_2030 4.3e-39 153.0 COG3383@1|root,COG3383@2|Bacteria,1WJDD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD1_k127_4099873_0 264732.Moth_2312 4.582e-193 616.0 COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,42FDP@68295|Thermoanaerobacterales 186801|Clostridia C Formate dehydrogenase alpha subunit fdhA - 1.17.1.10,1.17.1.9 ko:K00123,ko:K05299 ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200 M00377 R00134,R00519 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD1_k127_4099873_8 926569.ANT_08200 5.281e-87 296.0 COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi 200795|Chloroflexi S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD1_k127_4099873_7 926569.ANT_09040 1.83e-93 320.0 COG0265@1|root,COG0265@2|Bacteria,2G821@200795|Chloroflexi 200795|Chloroflexi O Trypsin - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - Trypsin_2 DYD1_k127_4125345_1 926569.ANT_02380 2.746e-129 419.0 COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C DYD1_k127_4125345_0 926569.ANT_22580 2.358e-183 595.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi 200795|Chloroflexi KLTU Protein tyrosine kinase - - - - - - - - - - - - PD40,Pkinase DYD1_k127_4125345_4 998674.ATTE01000001_gene3159 9.661e-15 85.0 COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria,4625I@72273|Thiotrichales 72273|Thiotrichales E Zn_pept - - - - - - - - - - - - Peptidase_M14 DYD1_k127_4125345_2 316274.Haur_1681 4.673e-117 390.0 COG4102@1|root,COG4102@2|Bacteria,2G79B@200795|Chloroflexi,3759N@32061|Chloroflexia 200795|Chloroflexi S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 DYD1_k127_4125345_3 240016.ABIZ01000001_gene5682 5.416e-103 352.0 COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 DYD1_k127_4136289_1 765420.OSCT_2229 4.568e-74 271.0 COG2843@1|root,COG2843@2|Bacteria,2GB5U@200795|Chloroflexi,377DF@32061|Chloroflexia 32061|Chloroflexia M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap DYD1_k127_4136289_0 765420.OSCT_2228 1.685e-173 569.0 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - DUF3160,YARHG,zinc_ribbon_2 DYD1_k127_414837_3 1122222.AXWR01000026_gene1658 9.805e-111 365.0 COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein DYD1_k127_414837_9 1173028.ANKO01000193_gene5867 1.013e-35 152.0 COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria 1117|Cyanobacteria KLT Serine Threonine protein kinase - - - - - - - - - - - - Pkinase,WD40 DYD1_k127_414837_11 1395571.TMS3_0108670 1.49e-25 110.0 COG1679@1|root,COG1786@1|root,COG1679@2|Bacteria,COG1786@2|Bacteria,1NFH4@1224|Proteobacteria,1S4TW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF521) - - - ko:K09123 - - - - ko00000 - - - DUF126,DUF521 DYD1_k127_414837_1 1118054.CAGW01000081_gene2691 3.047e-134 440.0 COG1679@1|root,COG1786@1|root,COG1679@2|Bacteria,COG1786@2|Bacteria,1UJDG@1239|Firmicutes,4HTS5@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF521) - - - ko:K09123 - - - - ko00000 - - - DUF521 DYD1_k127_414837_0 1157490.EL26_03800 1.23e-140 464.0 COG1164@1|root,COG1164@2|Bacteria,1U8XY@1239|Firmicutes,4HEV8@91061|Bacilli 91061|Bacilli E Peptidase M3A and M3B thimet oligopeptidase F - - - - - - - - - - - - Peptidase_M2,Peptidase_M3 DYD1_k127_414837_7 290397.Adeh_3050 3.655e-70 249.0 COG1215@1|root,COG1215@2|Bacteria,1QVTJ@1224|Proteobacteria 1224|Proteobacteria M COG0463 Glycosyltransferases involved in cell wall biogenesis wbyL - - ko:K13002 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 DYD1_k127_414837_8 1317122.ATO12_18095 5.909e-65 235.0 COG0463@1|root,COG0463@2|Bacteria,4PM7S@976|Bacteroidetes,1IMR6@117743|Flavobacteriia,2YIFS@290174|Aquimarina 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_414837_10 43989.cce_0521 8.32e-30 129.0 COG2520@1|root,COG2520@2|Bacteria,1GA8M@1117|Cyanobacteria 1117|Cyanobacteria J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 DYD1_k127_414837_2 526227.Mesil_0359 1.818e-121 394.0 COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase DYD1_k127_414837_5 1128421.JAGA01000002_gene351 2.675e-102 341.0 COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria 2|Bacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase DYD1_k127_414837_6 765420.OSCT_0762 5.737e-76 265.0 COG1893@1|root,COG1893@2|Bacteria,2G9PB@200795|Chloroflexi,3772C@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C DYD1_k127_414837_4 370438.PTH_0220 5.19e-107 356.0 COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae 186801|Clostridia H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf DYD1_k127_414837_12 357808.RoseRS_0605 1.874e-10 68.0 COG0823@1|root,COG0823@2|Bacteria,2GB83@200795|Chloroflexi,377J2@32061|Chloroflexia 32061|Chloroflexia U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - DYD1_k127_4148505_4 926569.ANT_19020 1.747e-14 74.0 COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi 200795|Chloroflexi J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD1_k127_4148505_5 1236494.BAJN01000004_gene735 3.749e-05 48.0 2BUU6@1|root,32Q5V@2|Bacteria,4PBMA@976|Bacteroidetes,2FZ7U@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_4148505_3 926569.ANT_30550 1.016e-60 218.0 COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi 200795|Chloroflexi J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind DYD1_k127_4148505_0 287.DR97_91 1.475e-126 419.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1YEDD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECUMN_1333.ECUMN_0566,iJN746.PP_2905 DALR_2,tRNA-synt_1e,tRNA-synt_1g DYD1_k127_4148505_1 485913.Krac_11275 3.005e-102 343.0 COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi 200795|Chloroflexi S SMART Nucleotide binding protein, PINc - - - - - - - - - - - - TRAM DYD1_k127_4148505_2 926569.ANT_09040 3.316e-77 267.0 COG0265@1|root,COG0265@2|Bacteria,2G821@200795|Chloroflexi 200795|Chloroflexi O Trypsin - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - Trypsin_2 DYD1_k127_4155085_3 926569.ANT_01450 3.014e-69 238.0 COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi 200795|Chloroflexi F Phosphoribosyl transferase domain - - - ko:K07101 - - - - ko00000 - - - Pribosyltran DYD1_k127_4155085_0 1128421.JAGA01000002_gene455 9.511e-75 265.0 COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 DYD1_k127_4155085_10 926569.ANT_28270 1.206e-22 98.0 2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi 200795|Chloroflexi J Ribosomal protein S21 rpsU - - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 DYD1_k127_4155085_9 926569.ANT_28280 1.445e-32 128.0 COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi 200795|Chloroflexi J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a DYD1_k127_4155085_1 1185652.USDA257_c09580 4.22e-73 266.0 COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,4B70K@82115|Rhizobiaceae 28211|Alphaproteobacteria T Histidine kinase kdpD - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp DYD1_k127_4155085_2 247156.NFA_15700 3.354e-70 248.0 COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4FUQS@85025|Nocardiaceae 201174|Actinobacteria T Transcriptional regulatory protein, C terminal kdpE GO:0008150,GO:0040007 - ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_4155085_5 671143.DAMO_1519 7.646e-60 233.0 COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria 2|Bacteria E Amino acid permease ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 DYD1_k127_4155085_8 765420.OSCT_1596 6.41e-38 147.0 COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi,3777S@32061|Chloroflexia 32061|Chloroflexia C TrkA-N domain - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD1_k127_4155085_4 671143.DAMO_1521 3.766e-69 247.0 COG0569@1|root,COG0569@2|Bacteria,2NPN3@2323|unclassified Bacteria 2|Bacteria P TrkA-C domain trkA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD1_k127_4155085_7 1318628.MARLIPOL_05015 1.342e-42 168.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,4650B@72275|Alteromonadaceae 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA DYD1_k127_4155085_6 926569.ANT_25040 7.713e-57 201.0 COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi 200795|Chloroflexi O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD1_k127_4176725_1 357808.RoseRS_2395 3.207e-79 274.0 COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia 32061|Chloroflexia M short-chain dehydrogenase reductase SDR - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD1_k127_4176725_0 926569.ANT_22620 6.555e-246 775.0 COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi 200795|Chloroflexi GM Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 DYD1_k127_4182622_7 926569.ANT_24750 2.451e-30 124.0 COG2010@1|root,COG2010@2|Bacteria,2G7FH@200795|Chloroflexi 200795|Chloroflexi C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD1_k127_4182622_4 1330700.JQNC01000003_gene911 1.413e-62 234.0 COG3258@1|root,COG3258@2|Bacteria,1WMNM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD1_k127_4182622_9 312153.Pnuc_0456 1.75e-16 91.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,1K4XR@119060|Burkholderiaceae 28216|Betaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N DYD1_k127_4182622_6 552811.Dehly_0442 3.86e-59 218.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Cytochrom_c3_2 DYD1_k127_4182622_8 290318.Cvib_0750 1.592e-23 101.0 COG1145@1|root,COG1145@2|Bacteria,1FEC9@1090|Chlorobi 1090|Chlorobi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4 DYD1_k127_4182622_5 675635.Psed_0410 5.026e-60 217.0 COG0265@1|root,COG0265@2|Bacteria,2IG6N@201174|Actinobacteria 201174|Actinobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 DYD1_k127_4182622_0 1121272.KB903249_gene1588 5.829e-141 455.0 COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DCFG@85008|Micromonosporales 201174|Actinobacteria S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD1_k127_4182622_1 296591.Bpro_3892 1.911e-99 334.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 DYD1_k127_4182622_3 675635.Psed_0413 7.544e-83 289.0 COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DYPB@85010|Pseudonocardiales 201174|Actinobacteria S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 DYD1_k127_4182622_2 543632.JOJL01000024_gene2085 1.48e-93 319.0 COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4D9FN@85008|Micromonosporales 201174|Actinobacteria S protein containing a von Willebrand factor type A (vWA) domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 DYD1_k127_4184891_0 926569.ANT_01210 4.534e-202 638.0 COG0402@1|root,COG0402@2|Bacteria,2G5X1@200795|Chloroflexi 200795|Chloroflexi F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD1_k127_4188748_2 1128421.JAGA01000002_gene1343 2.074e-44 173.0 COG5640@1|root,COG5640@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - - - - - - - - - - - Trypsin DYD1_k127_4188748_1 324602.Caur_1783 1.195e-83 294.0 COG2211@1|root,COG2211@2|Bacteria,2G6RZ@200795|Chloroflexi 200795|Chloroflexi G MFS/sugar transport protein - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 DYD1_k127_4188748_3 1172188.KB911822_gene725 7.09e-41 164.0 COG5640@1|root,COG5640@2|Bacteria,2IB3X@201174|Actinobacteria,4FH3T@85021|Intrasporangiaceae 201174|Actinobacteria O Trypsin-like serine protease - - - - - - - - - - - - Trypsin DYD1_k127_4188748_0 710696.Intca_3418 2.496e-269 838.0 COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4FG03@85021|Intrasporangiaceae 201174|Actinobacteria S Immune inhibitor A peptidase M6 - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 DYD1_k127_4191817_3 1254432.SCE1572_20250 1.364e-25 109.0 COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997,ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_4191817_0 1254432.SCE1572_20250 3.568e-151 492.0 COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997,ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_4191817_2 316274.Haur_2262 4.311e-71 249.0 COG0745@1|root,COG0745@2|Bacteria,2G81R@200795|Chloroflexi 200795|Chloroflexi K Two component transcriptional regulator, winged helix family - - - - - - - - - - - - Response_reg,Trans_reg_C DYD1_k127_4191817_1 316274.Haur_2261 6.482e-148 505.0 COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,2G8T7@200795|Chloroflexi,3780G@32061|Chloroflexia 2|Bacteria T histidine kinase HAMP region domain protein - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,dCache_1 DYD1_k127_4206218_2 479434.Sthe_2327 5.673e-84 288.0 COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,27XMR@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX - - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase DYD1_k127_4206218_0 760568.Desku_1514 5.786e-177 564.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,26072@186807|Peptococcaceae 186801|Clostridia H PFAM Aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_4206218_1 383372.Rcas_0368 3.038e-152 487.0 COG0451@1|root,COG0451@2|Bacteria,2G5PB@200795|Chloroflexi,37576@32061|Chloroflexia 32061|Chloroflexia M short-chain dehydrogenase reductase SDR - - - - - - - - - - - - Epimerase DYD1_k127_4232733_7 555779.Dthio_PD3240 1.83e-59 226.0 COG3640@1|root,COG3640@2|Bacteria,1R819@1224|Proteobacteria,42PQR@68525|delta/epsilon subdivisions,2WKE4@28221|Deltaproteobacteria 28221|Deltaproteobacteria D PFAM Cobyrinic acid ac-diamide synthase - - - ko:K07321 - - - - ko00000 - - - CbiA DYD1_k127_4232733_4 311424.DhcVS_1445 2.488e-94 319.0 2A40N@1|root,30SJ6@2|Bacteria,2G9WM@200795|Chloroflexi,34DKR@301297|Dehalococcoidia 301297|Dehalococcoidia - - - - - - - - - - - - - - - DYD1_k127_4232733_2 264732.Moth_1200 2.933e-157 519.0 COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales 186801|Clostridia C PFAM ferredoxin - - - - - - - - - - - - DUF4445,Fer2 DYD1_k127_4232733_14 179408.Osc7112_5196 3.62e-17 91.0 COG0515@1|root,COG0515@2|Bacteria,1G8NX@1117|Cyanobacteria,1HCBP@1150|Oscillatoriales 1117|Cyanobacteria KLT serine threonine protein kinase - - - - - - - - - - - - - DYD1_k127_4232733_3 429009.Adeg_0337 1.18e-128 424.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,42EP5@68295|Thermoanaerobacterales 186801|Clostridia C CO dehydrogenase/acetyl-CoA synthase delta subunit acsC - 2.1.1.245 ko:K00197 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 M00357,M00377,M00422 R09096,R10219,R10243 RC00004,RC00113,RC02977 ko00000,ko00001,ko00002,ko01000 - - - CdhD,FeS DYD1_k127_4232733_5 903818.KI912268_gene1657 8.536e-89 305.0 COG2069@1|root,COG2069@2|Bacteria 2|Bacteria C one-carbon metabolic process acsD - 1.2.7.4,2.1.1.245 ko:K00194,ko:K00198 ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200 M00357,M00377,M00422 R07157,R08034,R09096,R10219,R10243 RC00004,RC00113,RC00250,RC02800,RC02977 ko00000,ko00001,ko00002,ko01000 - - - CdhD,MTHFR DYD1_k127_4232733_0 555779.Dthio_PD3239 2.313e-259 820.0 COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria 28221|Deltaproteobacteria C PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit - - 2.3.1.169 ko:K14138 ko00720,ko01120,ko01200,map00720,map01120,map01200 M00377 R08433,R10243 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 ko00000,ko00001,ko00002,ko01000 - - - CdhC DYD1_k127_4232733_1 909663.KI867150_gene97 1.111e-221 706.0 COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales 28221|Deltaproteobacteria C TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit - - 1.2.7.4 ko:K00198 ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200 M00377 R07157,R08034 RC00250,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Prismane DYD1_k127_4232733_10 555088.DealDRAFT_2860 1.153e-44 175.0 COG1810@1|root,COG1810@2|Bacteria,1V28Y@1239|Firmicutes,24DXC@186801|Clostridia 186801|Clostridia S Domain of unknown function - - - - - - - - - - - - DUF166 DYD1_k127_4232733_9 926550.CLDAP_10440 2.644e-47 186.0 COG0438@1|root,COG0438@2|Bacteria,2G6KX@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 DYD1_k127_4232733_13 317936.Nos7107_0437 2.555e-19 98.0 COG1215@1|root,COG1215@2|Bacteria,1FZZM@1117|Cyanobacteria,1HIVP@1161|Nostocales 1117|Cyanobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_4232733_12 247490.KSU1_C1619 1.48e-19 100.0 COG1216@1|root,COG1216@2|Bacteria,2J0NC@203682|Planctomycetes 203682|Planctomycetes G Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_4232733_11 1142394.PSMK_19720 1.099e-22 111.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_4232733_6 926550.CLDAP_30040 7.476e-86 310.0 COG0642@1|root,COG2205@2|Bacteria 926550.CLDAP_30040|- T PhoQ Sensor - - - - - - - - - - - - - DYD1_k127_4232733_8 926550.CLDAP_30050 1.523e-56 220.0 COG0745@1|root,COG0745@2|Bacteria 926550.CLDAP_30050|- T phosphorelay signal transduction system - - - ko:K07670 ko02020,map02020 M00461 - - ko00000,ko00001,ko00002,ko02022 - - - - DYD1_k127_423772_3 1380391.JIAS01000004_gene2958 1.237e-80 277.0 COG1414@1|root,COG1414@2|Bacteria,1R3WU@1224|Proteobacteria,2U102@28211|Alphaproteobacteria,2JYGH@204441|Rhodospirillales 204441|Rhodospirillales K Bacterial transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR DYD1_k127_423772_0 1380391.JIAS01000004_gene2956 5.404e-166 532.0 COG4948@1|root,COG4948@2|Bacteria,1R8NF@1224|Proteobacteria,2UPFU@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD1_k127_423772_5 706587.Desti_0899 1.995e-25 111.0 COG2329@1|root,COG2329@2|Bacteria,1NDM8@1224|Proteobacteria 1224|Proteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ydhR DYD1_k127_423772_2 1380391.JIAS01000012_gene4445 4.404e-82 280.0 COG1028@1|root,COG1028@2|Bacteria,1R90U@1224|Proteobacteria,2U330@28211|Alphaproteobacteria,2JSWR@204441|Rhodospirillales 204441|Rhodospirillales IQ KR domain - - - - - - - - - - - - adh_short_C2 DYD1_k127_423772_1 395964.KE386496_gene664 1.818e-122 398.0 COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,2TSIG@28211|Alphaproteobacteria,3NAS1@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase,TAT_signal DYD1_k127_423772_4 1122962.AULH01000024_gene3532 1.609e-55 196.0 COG2315@1|root,COG2315@2|Bacteria,1RHEZ@1224|Proteobacteria,2U97K@28211|Alphaproteobacteria,36YC1@31993|Methylocystaceae 28211|Alphaproteobacteria S YjbR - - - - - - - - - - - - YjbR DYD1_k127_423772_6 331869.BAL199_18471 2.32e-07 53.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ABC-type multidrug transport system ATPase and permease - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_4283843_0 1123355.JHYO01000002_gene1344 3.346e-289 893.0 COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2TTB5@28211|Alphaproteobacteria,36ZGZ@31993|Methylocystaceae 28211|Alphaproteobacteria C Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - COX2,Cupredoxin_1 DYD1_k127_4283843_1 1123355.JHYO01000002_gene1343 1.075e-282 895.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2TR0X@28211|Alphaproteobacteria,36XKY@31993|Methylocystaceae 28211|Alphaproteobacteria CK FMN_bind nosR - - ko:K19339 - - - - ko00000,ko03000 - - - FMN_bind,Fer4_5 DYD1_k127_4283843_2 1121033.AUCF01000004_gene4661 6.636e-25 108.0 COG1633@1|root,COG1633@2|Bacteria,1R5CQ@1224|Proteobacteria,2U0D5@28211|Alphaproteobacteria,2JU9N@204441|Rhodospirillales 204441|Rhodospirillales S Rubrerythrin - - - - - - - - - - - - Rubrerythrin DYD1_k127_4321242_1 926569.ANT_05670 2.402e-174 556.0 COG0074@1|root,COG0074@2|Bacteria,2G7UI@200795|Chloroflexi 200795|Chloroflexi C Protein of unknown function (DUF1116) - - - - - - - - - - - - DUF1116 DYD1_k127_4321242_6 65093.PCC7418_0472 5.736e-19 89.0 2B1XW@1|root,31UE7@2|Bacteria,1G79D@1117|Cyanobacteria 1117|Cyanobacteria J PFAM S23 ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_4321242_2 1382356.JQMP01000003_gene1475 1.089e-151 481.0 COG1878@1|root,COG1878@2|Bacteria,2GBDZ@200795|Chloroflexi,27Z1S@189775|Thermomicrobia 189775|Thermomicrobia S Putative cyclase - - - - - - - - - - - - Cyclase DYD1_k127_4321242_5 485913.Krac_1779 9.619e-20 95.0 COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi 2|Bacteria S Protein of unknown function (DUF1706) M1-431 - - - - - - - - - - - DUF1706 DYD1_k127_4321242_0 1038860.AXAP01000027_gene1889 0.0 1122.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_4321242_3 926569.ANT_05730 2.564e-147 480.0 COG2233@1|root,COG2233@2|Bacteria,2G8VZ@200795|Chloroflexi 200795|Chloroflexi F Permease family - - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease DYD1_k127_4321242_8 1121468.AUBR01000034_gene1369 1.036e-17 91.0 COG1456@1|root,COG1456@2|Bacteria,1UIEM@1239|Firmicutes,25EJY@186801|Clostridia,42GZB@68295|Thermoanaerobacterales 186801|Clostridia C Domain of unknown function (DUF3786) - - - - - - - - - - - - DUF3786 DYD1_k127_4321242_7 383372.Rcas_0509 6.796e-18 96.0 COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi 200795|Chloroflexi S integral membrane protein - - - - - - - - - - - - Mannosyl_trans2 DYD1_k127_4321242_4 1306406.ASHX01000001_gene4469 4.801e-67 262.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - CHAP,DUF11,PKD,PPC DYD1_k127_4321242_11 714943.Mucpa_7167 9.67e-12 80.0 COG1208@1|root,COG3420@1|root,COG5184@1|root,COG5492@1|root,COG1208@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NMRB@976|Bacteroidetes,1ITFX@117747|Sphingobacteriia 976|Bacteroidetes P Protein of unknown function (DUF3494) - - - - - - - - - - - - Big_5,DUF3494,Flg_new DYD1_k127_4321242_10 926550.CLDAP_18450 1.565e-13 86.0 2F121@1|root,33TFM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4335436_0 580332.Slit_0145 1.131e-128 423.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales 28216|Betaproteobacteria J S-adenosylmethionine-dependent methyltransferase rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM DYD1_k127_4335436_1 1157632.AQWQ01000016_gene3366 2.604e-54 196.0 COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria 201174|Actinobacteria E Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA - - - - - - - - - - - - Aminotran_1_2,KR,PP-binding,PS-DH DYD1_k127_4363706_6 315730.BcerKBAB4_2261 3.453e-29 121.0 2DNMG@1|root,32Y46@2|Bacteria,1VK1T@1239|Firmicutes,4HNYW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_4363706_4 479434.Sthe_3216 5.291e-34 141.0 COG0265@1|root,COG0265@2|Bacteria,2G8UH@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase S1 and S6, chymotrypsin Hap - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD1_k127_4363706_2 926550.CLDAP_00060 8.128e-91 307.0 COG0265@1|root,COG0265@2|Bacteria,2G6I9@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase S1 and S6, chymotrypsin Hap - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD1_k127_4363706_5 404589.Anae109_0915 1.132e-32 137.0 COG2197@1|root,COG2197@2|Bacteria,1NCBR@1224|Proteobacteria,433WZ@68525|delta/epsilon subdivisions,2X3XU@28221|Deltaproteobacteria,2YXHT@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE DYD1_k127_4363706_3 477974.Daud_1296 4.592e-47 179.0 2ASZS@1|root,31IFG@2|Bacteria,1V50D@1239|Firmicutes,24PRN@186801|Clostridia,262PV@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_4363706_0 926569.ANT_22870 4.577e-160 516.0 COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi 200795|Chloroflexi F PFAM glycosyl transferase family 3 pdp - 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C DYD1_k127_4363706_1 926569.ANT_21050 3.373e-91 308.0 COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - - - - - - - - - - - Amidohydro_1,CYTH DYD1_k127_4398363_1 926569.ANT_07430 2.133e-91 312.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi 200795|Chloroflexi M Peptidoglycan-binding LysM - - - - - - - - - - - - LysM,Peptidase_M23,SH3_3 DYD1_k127_4398363_0 926569.ANT_09360 8.583e-203 637.0 COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi 200795|Chloroflexi K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind DYD1_k127_4437492_1 357808.RoseRS_0300 1.195e-32 132.0 COG1943@1|root,COG1943@2|Bacteria,2G88H@200795|Chloroflexi,377A5@32061|Chloroflexia 32061|Chloroflexia L Transposase IS200 like - - - - - - - - - - - - - DYD1_k127_4437492_0 926569.ANT_23100 0.0 1404.0 COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi 200795|Chloroflexi L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD1_k127_4458230_2 926569.ANT_19100 3.272e-133 432.0 COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi 200795|Chloroflexi S PFAM conserved - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_4458230_1 926569.ANT_19090 1.44e-165 535.0 COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi 200795|Chloroflexi H PFAM amine oxidase - - - - - - - - - - - - Amino_oxidase DYD1_k127_4458230_27 926569.ANT_26900 1.463e-05 57.0 COG0823@1|root,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 4.6.1.13 ko:K01771 ko00562,map00562 - R03332 RC00017,RC00425 ko00000,ko00001,ko01000 - - - PD40,PI-PLC-X DYD1_k127_4458230_22 316274.Haur_3677 2.49e-23 106.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_4458230_20 485913.Krac_11078 1.797e-39 153.0 COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi 200795|Chloroflexi J Aminoacyl-tRNA editing domain - - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit DYD1_k127_4458230_26 72019.SARC_08906T0 2.14e-06 54.0 2F5I8@1|root,2T6J2@2759|Eukaryota,3AE5T@33154|Opisthokonta 33154|Opisthokonta - - - - - - - - - - - - - - - DYD1_k127_4458230_28 929556.Solca_1759 0.0001232 53.0 2EM7W@1|root,33EX0@2|Bacteria,4P5SH@976|Bacteroidetes,1J02V@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_4458230_4 926569.ANT_29410 4.085e-119 394.0 COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi 200795|Chloroflexi E peptidase M29 aminopeptidase II - - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 DYD1_k127_4458230_3 1267535.KB906767_gene1575 2.112e-123 427.0 COG2133@1|root,COG2133@2|Bacteria,3Y6R6@57723|Acidobacteria,2JMHE@204432|Acidobacteriia 204432|Acidobacteriia G pyrroloquinoline quinone binding - - - - - - - - - - - - - DYD1_k127_4458230_24 1122222.AXWR01000013_gene1020 2.045e-18 93.0 COG3415@1|root,COG3415@2|Bacteria,1WNFW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Protein of unknown function (DUF3105) - - - - - - - - - - - - DUF3105 DYD1_k127_4458230_21 304371.MCP_2156 3.202e-29 124.0 COG1309@1|root,arCOG02643@2157|Archaea,2Y6WH@28890|Euryarchaeota,2NB9B@224756|Methanomicrobia 224756|Methanomicrobia K Bacterial regulatory proteins, tetR family - - - ko:K03577 - M00647 - - ko00000,ko00002,ko03000 - - - TetR_N DYD1_k127_4458230_0 469383.Cwoe_1088 1.16e-200 637.0 COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria 84995|Rubrobacteria C Belongs to the citrate synthase family - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD1_k127_4458230_18 926550.CLDAP_07560 2.556e-43 174.0 COG0558@1|root,COG0558@2|Bacteria,2G8YS@200795|Chloroflexi 200795|Chloroflexi I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD1_k127_4458230_15 926550.CLDAP_07570 1.32e-50 199.0 COG0392@1|root,COG0392@2|Bacteria,2G96G@200795|Chloroflexi 200795|Chloroflexi S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_4458230_14 886293.Sinac_7569 2.654e-54 210.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase DYD1_k127_4458230_12 706587.Desti_2991 3.231e-60 219.0 COG0030@1|root,COG0030@2|Bacteria 2|Bacteria J rRNA (adenine-N6,N6-)-dimethyltransferase activity ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 ko:K00561,ko:K02528 - - R10716 RC00003,RC03257 br01600,ko00000,ko01000,ko01504,ko03009 - - - Methyltransf_11,RrnaAD DYD1_k127_4458230_7 1197130.BAFM01000016_gene2564 4.676e-90 309.0 COG0438@1|root,arCOG01407@2157|Archaea,2Y8BB@28890|Euryarchaeota,24180@183963|Halobacteria 183963|Halobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_4458230_19 926550.CLDAP_31610 7.324e-42 158.0 COG0720@1|root,COG0720@2|Bacteria,2G7B6@200795|Chloroflexi 200795|Chloroflexi H PFAM 6-pyruvoyl tetrahydropterin synthase and - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS DYD1_k127_4458230_5 662479.C440_13264 1.098e-102 351.0 COG1063@1|root,arCOG01621@2157|Archaea,2XTZT@28890|Euryarchaeota,23SIP@183963|Halobacteria 183963|Halobacteria E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - - - - - - - - - - ADH_zinc_N DYD1_k127_4458230_11 926550.CLDAP_31590 5.564e-65 236.0 COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,2G63D@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K01497,ko:K14652 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 DYD1_k127_4458230_9 1123228.AUIH01000017_gene3646 1.346e-73 254.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1XI3J@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA - 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 DYD1_k127_4458230_23 263358.VAB18032_02070 2.617e-23 104.0 COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4DEKA@85008|Micromonosporales 201174|Actinobacteria P Belongs to the Fur family - - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR DYD1_k127_4458230_8 926569.ANT_12690 5.943e-81 280.0 COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi 200795|Chloroflexi P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import - - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM,PDGLE DYD1_k127_4458230_13 383372.Rcas_4361 4.087e-58 211.0 COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi,37758@32061|Chloroflexia 32061|Chloroflexia P TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ - - - ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiQ DYD1_k127_4458230_6 357808.RoseRS_0169 6.966e-92 309.0 COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi,3764I@32061|Chloroflexia 32061|Chloroflexia P ABC transporter - - - ko:K02006 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - ABC_tran DYD1_k127_4458230_10 309801.trd_0274 4.025e-69 250.0 COG5438@1|root,COG5438@2|Bacteria 2|Bacteria S YibE/F-like protein yibE - - - - - - - - - - - YibE_F DYD1_k127_4458230_16 765420.OSCT_1795 1.265e-46 181.0 COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia 32061|Chloroflexia CO PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA DYD1_k127_4458230_17 926569.ANT_20530 1.093e-44 180.0 COG0682@1|root,COG0682@2|Bacteria,2G8YW@200795|Chloroflexi 200795|Chloroflexi M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD1_k127_4469909_5 926569.ANT_15760 1.001e-98 335.0 COG1376@1|root,COG1376@2|Bacteria 2|Bacteria D ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - YkuD DYD1_k127_4469909_8 326427.Cagg_2623 1.053e-77 271.0 COG0517@1|root,COG0517@2|Bacteria,2G6TI@200795|Chloroflexi,376YQ@32061|Chloroflexia 32061|Chloroflexia S amino acid-binding ACT domain protein - - - ko:K04767 - - - - ko00000 - - - CBS DYD1_k127_4469909_14 1313172.YM304_34420 3.169e-25 116.0 COG2267@1|root,COG2267@2|Bacteria,2HF8H@201174|Actinobacteria,4CNE1@84992|Acidimicrobiia 84992|Acidimicrobiia I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_4469909_13 696281.Desru_1167 1.59e-30 130.0 COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,262QN@186807|Peptococcaceae 186801|Clostridia J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase DYD1_k127_4469909_12 1121430.JMLG01000005_gene683 1.779e-37 149.0 COG1611@1|root,COG1611@2|Bacteria,1V2D7@1239|Firmicutes,24KYJ@186801|Clostridia,262X1@186807|Peptococcaceae 186801|Clostridia S TIGRFAM TIGR00725 family protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD1_k127_4469909_15 1382306.JNIM01000001_gene1619 4.337e-23 109.0 COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi 200795|Chloroflexi J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD1_k127_4469909_10 926569.ANT_18710 1.388e-69 238.0 COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi 200795|Chloroflexi F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK DYD1_k127_4469909_4 926569.ANT_18700 3.523e-102 375.0 COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi 200795|Chloroflexi O Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Sigma70_r1_1,TPR_16,TPR_19,TPR_8 DYD1_k127_4469909_6 357808.RoseRS_3190 1.399e-83 290.0 COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,374Z1@32061|Chloroflexia 32061|Chloroflexia BQ PFAM histone deacetylase superfamily - - - - - - - - - - - - Hist_deacetyl DYD1_k127_4469909_11 485913.Krac_8769 5.811e-41 166.0 2CC95@1|root,2Z8VE@2|Bacteria,2G92N@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_4469909_9 926550.CLDAP_21460 3.599e-70 248.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2,GtrA DYD1_k127_4469909_19 1115515.EV102420_02_03850 4.157e-05 53.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,3XN7X@561|Escherichia 1236|Gammaproteobacteria K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 DYD1_k127_4469909_1 926550.CLDAP_21470 9.088e-135 438.0 COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi 200795|Chloroflexi M Belongs to the DegT DnrJ EryC1 family - - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 DYD1_k127_4469909_18 1123060.JONP01000001_gene1447 1.459e-06 62.0 COG0457@1|root,COG0457@2|Bacteria,1N0DE@1224|Proteobacteria,2UCGA@28211|Alphaproteobacteria,2JTE7@204441|Rhodospirillales 204441|Rhodospirillales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_2 DYD1_k127_4469909_16 378806.STAUR_1605 2.3e-14 87.0 COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria,2YVDU@29|Myxococcales 28221|Deltaproteobacteria M O-antigen ligase like membrane protein - - - ko:K18814 - - - - ko00000,ko02000 9.B.67.1 - - TPR_14,TPR_16,TPR_8,Wzy_C DYD1_k127_4469909_0 1195236.CTER_0541 2.932e-299 937.0 COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WHVU@541000|Ruminococcaceae 186801|Clostridia C pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase DYD1_k127_4469909_2 926569.ANT_18650 1.872e-117 387.0 COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 DYD1_k127_4469909_7 926569.ANT_18660 3.507e-79 271.0 COG1277@1|root,COG1277@2|Bacteria 2|Bacteria - - yxlG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux DYD1_k127_4469909_3 926569.ANT_18670 8.251e-111 377.0 COG3225@1|root,COG3225@2|Bacteria 2|Bacteria - - gldG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux DYD1_k127_4469909_17 321327.CYA_2879 3.198e-07 59.0 2DN50@1|root,32VJ4@2|Bacteria,1GND9@1117|Cyanobacteria,1H0SG@1129|Synechococcus 1117|Cyanobacteria S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 DYD1_k127_449659_0 1380390.JIAT01000009_gene1860 6.262e-139 455.0 COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4CPFR@84995|Rubrobacteria 84995|Rubrobacteria M Glycosyl transferases group 1 - - 2.4.1.245 ko:K13057 ko00500,ko01100,map00500,map01100 - R08946,R10525,R11306 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000 - GT4 - Glycos_transf_1 DYD1_k127_449659_1 935840.JAEQ01000003_gene117 2.19e-89 312.0 COG0395@1|root,COG0395@2|Bacteria,1MUMG@1224|Proteobacteria,2TVBP@28211|Alphaproteobacteria,43HIQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Binding-protein-dependent transport system inner membrane aglG - - ko:K10234 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - BPD_transp_1 DYD1_k127_449659_3 118168.MC7420_8037 2.27e-79 276.0 COG1175@1|root,COG1175@2|Bacteria,1G3BG@1117|Cyanobacteria,1H8SB@1150|Oscillatoriales 1117|Cyanobacteria G COG1175 ABC-type sugar transport systems permease components - - - ko:K10233 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - BPD_transp_1 DYD1_k127_449659_4 373903.Hore_13200 1.058e-58 223.0 COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes 1239|Firmicutes G ABC transporter, substratebinding protein - - - ko:K10232 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - SBP_bac_1 DYD1_k127_449659_2 526227.Mesil_3179 2.168e-79 276.0 COG1609@1|root,COG1609@2|Bacteria,1WMBZ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K PFAM Bacterial regulatory proteins, lacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 DYD1_k127_4506545_9 479434.Sthe_2445 4.129e-05 48.0 COG0697@1|root,COG0697@2|Bacteria,2G8R9@200795|Chloroflexi 200795|Chloroflexi EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_4506545_0 926550.CLDAP_32690 7.275e-222 706.0 COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2G7SW@200795|Chloroflexi 200795|Chloroflexi C Domain of unknown function (DUF4445) - - - - - - - - - - - - DUF4445,Fer2 DYD1_k127_4506545_3 488538.SAR116_1087 9.758e-89 308.0 COG5012@1|root,COG5012@2|Bacteria,1RDEU@1224|Proteobacteria,2TVXN@28211|Alphaproteobacteria,4BPGX@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S B12 binding domain mtbC - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2 DYD1_k127_4506545_4 926550.CLDAP_19760 1.425e-83 289.0 COG0646@1|root,COG0646@2|Bacteria,2G674@200795|Chloroflexi 200795|Chloroflexi H Homocysteine S-methyltransferase - - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - S-methyl_trans DYD1_k127_4506545_6 1298863.AUEP01000022_gene1863 1.877e-53 196.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - 1.11.1.15 ko:K03386,ko:K03564,ko:K16922 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko01002,ko04147 - - - AhpC-TSA,Redoxin DYD1_k127_4506545_5 926550.CLDAP_19800 8.648e-64 227.0 28I8Y@1|root,2Z8BR@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1638) - - - - - - - - - - - - DUF1638 DYD1_k127_4506545_8 314265.R2601_25161 9.332e-17 87.0 2CDZD@1|root,32RYT@2|Bacteria,1N0AT@1224|Proteobacteria,2UBTM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Virulence factor - - - - - - - - - - - - Virulence_fact DYD1_k127_4506545_7 926550.CLDAP_19770 2.323e-41 157.0 COG0685@1|root,COG0685@2|Bacteria 2|Bacteria E methylenetetrahydrofolate reductase (NAD(P)H) activity - - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,MTHFR_C DYD1_k127_4506545_1 926550.CLDAP_19780 3.025e-139 450.0 COG0685@1|root,COG0685@2|Bacteria,2G7NU@200795|Chloroflexi 200795|Chloroflexi C PFAM Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR DYD1_k127_4506545_2 926550.CLDAP_19790 2.824e-123 404.0 COG1410@1|root,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi 200795|Chloroflexi H Methionine synthase B12-binding module cap domain protein - - 2.1.1.13,2.1.1.258 ko:K00548,ko:K15023 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230 M00017,M00377 R00946,R02289,R09365,R10243 RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans DYD1_k127_4507902_0 1283299.AUKG01000006_gene774 4.952e-43 172.0 COG3693@1|root,COG3693@2|Bacteria 2|Bacteria G endo-1,4-beta-xylanase activity abfB GO:0005575,GO:0005576 - - - - - - - - - - Cellulase,Glyco_hydro_62,RicinB_lectin_2,Ricin_B_lectin DYD1_k127_4507902_1 1206735.BAGG01000253_gene6117 2.487e-25 118.0 COG2319@1|root,COG2909@1|root,COG2319@2|Bacteria,COG2909@2|Bacteria,2GJN3@201174|Actinobacteria,4FUSK@85025|Nocardiaceae 201174|Actinobacteria L WD40 repeats - - - - - - - - - - - - NACHT,NB-ARC,PD40,Pentapeptide,TIR_2,WD40 DYD1_k127_4513558_1 926569.ANT_13770 2.209e-215 677.0 COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi 200795|Chloroflexi F Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N DYD1_k127_4513558_9 926569.ANT_13780 1.525e-85 292.0 COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi 200795|Chloroflexi C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt DYD1_k127_4513558_0 926569.ANT_13790 3.937e-236 741.0 COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi 200795|Chloroflexi F Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N DYD1_k127_4513558_21 926569.ANT_13800 1.11e-44 170.0 COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi 200795|Chloroflexi C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N DYD1_k127_4513558_5 401526.TcarDRAFT_1474 4.054e-104 347.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4H2HR@909932|Negativicutes 909932|Negativicutes D Cell shape determining protein MreB Mrl mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD1_k127_4513558_17 479434.Sthe_3033 1.125e-58 209.0 COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi 200795|Chloroflexi Q PFAM Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_31 DYD1_k127_4513558_13 926550.CLDAP_12000 7.215e-69 239.0 COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi 200795|Chloroflexi K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N DYD1_k127_4513558_4 926569.ANT_13200 2.149e-165 533.0 COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi 200795|Chloroflexi S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 DYD1_k127_4513558_20 309801.trd_0651 3.446e-45 171.0 COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,27Y96@189775|Thermomicrobia 189775|Thermomicrobia F Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD1_k127_4513558_10 861299.J421_3645 2.445e-85 291.0 COG0605@1|root,COG0605@2|Bacteria,1ZT7S@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N DYD1_k127_4513558_14 926569.ANT_21000 7.507e-64 221.0 COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_4 DYD1_k127_4513558_2 357808.RoseRS_3341 8.817e-195 619.0 COG1027@1|root,COG1027@2|Bacteria,2G5IV@200795|Chloroflexi,37644@32061|Chloroflexia 32061|Chloroflexia C PFAM fumarate lyase - - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 DYD1_k127_4513558_25 521045.Kole_0198 7.83e-30 128.0 COG1814@1|root,COG1814@2|Bacteria,2GDXP@200918|Thermotogae 200918|Thermotogae S VIT family - - - - - - - - - - - - VIT1 DYD1_k127_4513558_12 1382306.JNIM01000001_gene1471 6.18e-69 245.0 COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi 200795|Chloroflexi T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_4513558_3 1121918.ARWE01000001_gene3102 8.959e-182 585.0 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42PNI@68525|delta/epsilon subdivisions,2WJNF@28221|Deltaproteobacteria 28221|Deltaproteobacteria P PFAM natural resistance-associated macrophage protein mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp,Usp DYD1_k127_4513558_16 1379270.AUXF01000001_gene2649 2.159e-59 213.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Helix-turn-helix diphteria tox regulatory element - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA DYD1_k127_4513558_28 867903.ThesuDRAFT_00144 1.293e-17 89.0 COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia 186801|Clostridia S Mov34 MPN PAD-1 family - - 3.13.1.6 ko:K21140 ko04122,map04122 - R11524 RC00064,RC00090 ko00000,ko00001,ko01000 - - - Prok-JAB DYD1_k127_4513558_22 926569.ANT_04330 7.556e-35 153.0 COG0344@1|root,COG0344@2|Bacteria 2|Bacteria I acyl-phosphate glycerol-3-phosphate acyltransferase activity plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf DYD1_k127_4513558_15 296591.Bpro_0156 1.051e-61 219.0 COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2VRA3@28216|Betaproteobacteria,4AEK0@80864|Comamonadaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K07032 - - - - ko00000 - - - Glyoxalase DYD1_k127_4513558_26 926569.ANT_14580 3.357e-29 126.0 COG1989@1|root,COG1989@2|Bacteria 2|Bacteria NOU aspartic-type endopeptidase activity comC - 3.4.23.43 ko:K02236,ko:K02506,ko:K02654 - M00331,M00429 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 DYD1_k127_4513558_29 926569.ANT_19310 2.368e-17 91.0 COG4961@1|root,COG4961@2|Bacteria 2|Bacteria U PFAM TadE family protein - - - - - - - - - - - - TadE DYD1_k127_4513558_24 926569.ANT_19330 5.137e-31 140.0 COG2133@1|root,COG2755@1|root,COG4961@1|root,COG2133@2|Bacteria,COG2755@2|Bacteria,COG4961@2|Bacteria 2|Bacteria U PFAM TadE family protein - - - ko:K12287 - - - - ko00000,ko02044 - - - Lipase_GDSL_2,Malectin,TadE DYD1_k127_4513558_7 926569.ANT_19350 7.454e-103 365.0 COG0642@1|root,COG3283@1|root,COG2205@2|Bacteria,COG3283@2|Bacteria 2|Bacteria EK Transcriptional regulator of aromatic amino acids metabolism - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - ANTAR,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,LytTR,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_4513558_11 926569.ANT_19360 1.118e-77 266.0 COG0745@1|root,COG0745@2|Bacteria 926569.ANT_19360|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_4513558_23 926569.ANT_19330 1.982e-32 143.0 COG2133@1|root,COG2755@1|root,COG4961@1|root,COG2133@2|Bacteria,COG2755@2|Bacteria,COG4961@2|Bacteria 2|Bacteria U PFAM TadE family protein - - - ko:K12287 - - - - ko00000,ko02044 - - - Lipase_GDSL_2,Malectin,TadE DYD1_k127_4513558_18 439235.Dalk_2836 5.581e-49 188.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WM56@28221|Deltaproteobacteria,2MHKW@213118|Desulfobacterales 28221|Deltaproteobacteria T PFAM GGDEF domain containing protein - - - - - - - - - - - - GGDEF,Response_reg DYD1_k127_4513558_6 926569.ANT_16770 3.634e-103 343.0 COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi 200795|Chloroflexi U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG DYD1_k127_4513558_30 326427.Cagg_0504 3.663e-12 67.0 COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,375DY@32061|Chloroflexia 32061|Chloroflexia U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF DYD1_k127_4513558_8 309801.trd_0650 1.442e-99 339.0 COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,27XK4@189775|Thermomicrobia 189775|Thermomicrobia U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF DYD1_k127_4527383_9 368407.Memar_1425 2.692e-13 75.0 COG0704@1|root,arCOG00318@2157|Archaea,2XUA4@28890|Euryarchaeota,2N9P3@224756|Methanomicrobia 224756|Methanomicrobia K Phosphate uptake regulator, PhoU - - - - - - - - - - - - MazE_antitoxin,PhoU DYD1_k127_4527383_1 926569.ANT_23430 5.146e-135 451.0 COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi 200795|Chloroflexi F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N DYD1_k127_4527383_5 926569.ANT_23420 1.718e-99 337.0 COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi 200795|Chloroflexi M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C DYD1_k127_4527383_3 926569.ANT_23400 2.863e-119 406.0 COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi 200795|Chloroflexi M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_4527383_4 926569.ANT_23380 2.065e-111 371.0 COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi 200795|Chloroflexi M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 DYD1_k127_4527383_6 644966.Tmar_0868 3.586e-67 247.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WCI1@538999|Clostridiales incertae sedis 186801|Clostridia D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE DYD1_k127_4527383_0 926569.ANT_23360 4.873e-150 487.0 COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi 200795|Chloroflexi M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M DYD1_k127_4527383_2 926569.ANT_23350 1.091e-133 439.0 COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi 200795|Chloroflexi M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 DYD1_k127_4527383_7 357808.RoseRS_3781 1.001e-43 164.0 COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,374X6@32061|Chloroflexia 32061|Chloroflexia M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_4572622_3 926569.ANT_13140 1.808e-34 139.0 COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi 200795|Chloroflexi K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_4572622_6 1282361.ABAC402_06505 1.423e-16 85.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UFM5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Transglycosylase-associated protein MA20_19350 - - - - - - - - - - - Transgly_assoc DYD1_k127_4572622_5 314285.KT71_07424 3.062e-25 115.0 2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,1SMYA@1236|Gammaproteobacteria,1J9DI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4572622_0 926569.ANT_04370 0.0 1067.0 COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi 200795|Chloroflexi L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD1_k127_4572622_2 290512.Paes_1832 9.347e-58 213.0 COG1912@1|root,COG1912@2|Bacteria,1FDZ8@1090|Chlorobi 1090|Chlorobi M S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans DYD1_k127_4572622_1 926569.ANT_11050 8.158e-179 567.0 COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi 200795|Chloroflexi M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase DYD1_k127_4626537_2 926569.ANT_09920 3.475e-92 313.0 COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_4626537_1 926569.ANT_09930 3.426e-119 404.0 COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi 200795|Chloroflexi CP Stage II sporulation protein M - - - - - - - - - - - - ABC2_membrane,ABC2_membrane_2,SpoIIM DYD1_k127_4626537_3 518766.Rmar_1910 6.201e-49 184.0 COG1234@1|root,COG1234@2|Bacteria,4PM5W@976|Bacteroidetes,1FJ9T@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 DYD1_k127_4626537_4 326427.Cagg_0772 2.931e-28 119.0 COG0664@1|root,COG0664@2|Bacteria,2GBTI@200795|Chloroflexi,375RB@32061|Chloroflexia 32061|Chloroflexia T PFAM cyclic nucleotide-binding - - - - - - - - - - - - cNMP_binding DYD1_k127_4626537_5 926569.ANT_18300 1.634e-22 103.0 COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi 200795|Chloroflexi O Belongs to the small heat shock protein (HSP20) family - - - - - - - - - - - - HSP20 DYD1_k127_4626537_0 926569.ANT_18310 0.0 1094.0 COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi 200795|Chloroflexi O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD1_k127_4628483_0 926569.ANT_06270 6.679e-154 491.0 COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi 200795|Chloroflexi C Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD1_k127_4628483_1 1207063.P24_03061 4.982e-10 72.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,2JP8P@204441|Rhodospirillales 204441|Rhodospirillales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N DYD1_k127_4628483_2 1415780.JPOG01000001_gene1425 3.401e-05 48.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RNDN@1236|Gammaproteobacteria,1X5P2@135614|Xanthomonadales 135614|Xanthomonadales E Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs avtA - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2 DYD1_k127_4667757_2 926569.ANT_29210 1.959e-31 132.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - - - - - - - - - - Wzy_C DYD1_k127_4667757_0 1049564.TevJSym_at00360 1.281e-73 262.0 COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,1S0D6@1236|Gammaproteobacteria,1JAMS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferases group 1 wbbO - - ko:K21011 ko02025,map02025 - - - ko00000,ko00001,ko01003 - GT4 - Glyco_trans_4_2,Glycos_transf_1 DYD1_k127_4667757_1 1335760.ASTG01000017_gene3492 6.015e-38 156.0 COG4424@1|root,COG4424@2|Bacteria,1N2S4@1224|Proteobacteria,2UIR9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 DYD1_k127_4667757_3 266834.SM_b21237 1.393e-20 97.0 COG4424@1|root,COG4424@2|Bacteria,1N2S4@1224|Proteobacteria 1224|Proteobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 DYD1_k127_4688377_2 204669.Acid345_0343 4.66e-94 319.0 COG1085@1|root,COG1085@2|Bacteria,3Y41K@57723|Acidobacteria,2JMKJ@204432|Acidobacteriia 204432|Acidobacteriia C Domain of unknown function (DUF4921) - - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C DYD1_k127_4688377_3 909663.KI867149_gene3397 7.21e-37 141.0 COG4274@1|root,COG4274@2|Bacteria,1PUJQ@1224|Proteobacteria,42XN6@68525|delta/epsilon subdivisions,2WTHH@28221|Deltaproteobacteria 28221|Deltaproteobacteria S GYD domain - - - - - - - - - - - - GYD DYD1_k127_4688377_0 671143.DAMO_2369 8.622e-174 549.0 COG1234@1|root,COG1234@2|Bacteria,2NPC9@2323|unclassified Bacteria 2|Bacteria S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 DYD1_k127_4688377_1 1469607.KK073768_gene4663 2.102e-123 412.0 COG3547@1|root,COG3547@2|Bacteria,1GA7N@1117|Cyanobacteria,1HTM7@1161|Nostocales 1117|Cyanobacteria L PFAM Transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 DYD1_k127_4703491_2 1121430.JMLG01000021_gene1378 4.699e-45 173.0 COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,2621S@186807|Peptococcaceae 186801|Clostridia NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 DYD1_k127_4703491_8 1192034.CAP_6339 8.917e-07 60.0 COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2YVKD@29|Myxococcales 28221|Deltaproteobacteria NU Type IV pilus assembly protein PilM; gspL - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,PilM_2,PilN,T2SSL DYD1_k127_4703491_5 144197.XP_008279337.1 1.249e-08 67.0 2CN3M@1|root,2QTQF@2759|Eukaryota,39N06@33154|Opisthokonta,3CPJB@33208|Metazoa,3E5QD@33213|Bilateria,48RWK@7711|Chordata,49NAZ@7742|Vertebrata,4A8V2@7898|Actinopterygii 33208|Metazoa S Kelch motif - - - - - - - - - - - - Kelch_1,Kelch_2,Kelch_3,Kelch_4,Kelch_5,Kelch_6 DYD1_k127_4703491_7 1463895.JODA01000033_gene3072 1.871e-07 62.0 2C1B5@1|root,3404V@2|Bacteria,2IQAF@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - N_methyl DYD1_k127_4703491_1 1121272.KB903289_gene4106 2.397e-73 261.0 COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4DB2E@85008|Micromonosporales 201174|Actinobacteria NU Type II secretion system (T2SS), protein F - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF DYD1_k127_4703491_0 255470.cbdbA1302 2.368e-136 460.0 COG2804@1|root,COG2804@2|Bacteria,2GBGG@200795|Chloroflexi,34CTX@301297|Dehalococcoidia 301297|Dehalococcoidia NU Type II secretion system (T2SS), protein E, N-terminal domain gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N DYD1_k127_4703491_3 706587.Desti_5065 1.451e-25 113.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales 28221|Deltaproteobacteria K PFAM response regulator receiver - - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_4703491_6 479434.Sthe_2869 1.128e-07 61.0 COG0789@1|root,COG2203@1|root,COG0789@2|Bacteria,COG2203@2|Bacteria 2|Bacteria T Gaf domain - - 2.3.3.1 ko:K01647,ko:K18997,ko:K22491 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000,ko03000,ko03036 - - - B12-binding,Citrate_synt,HTH_17,MerR_1 DYD1_k127_4703491_4 420246.GTNG_2519 1.289e-21 94.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,1WEHW@129337|Geobacillus 91061|Bacilli F Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth DYD1_k127_4705418_2 289377.HL41_00600 2.074e-82 277.0 COG0655@1|root,COG0655@2|Bacteria,2GIFQ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S NADPH-dependent FMN reductase - - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red DYD1_k127_4705418_0 404589.Anae109_2025 0.0 1026.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2YUJ3@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N DYD1_k127_4705418_1 1173020.Cha6605_6113 8.241e-128 417.0 COG0837@1|root,COG0837@2|Bacteria,1G1TJ@1117|Cyanobacteria 1117|Cyanobacteria G Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase DYD1_k127_4705418_3 91464.S7335_1532 6.324e-32 132.0 COG0158@1|root,COG0158@2|Bacteria,1G0KA@1117|Cyanobacteria,1GYWN@1129|Synechococcus 1117|Cyanobacteria G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 - - - - - - - - - - - - FBPase DYD1_k127_4725787_7 1121324.CLIT_10c05480 1.265e-08 57.0 COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae 186801|Clostridia C Aldehyde ferredoxin oxidoreductase, N-terminal domain - - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N DYD1_k127_4725787_4 32057.KB217478_gene468 1.23e-42 158.0 COG0393@1|root,COG0393@2|Bacteria,1G7AD@1117|Cyanobacteria 1117|Cyanobacteria S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 DYD1_k127_4725787_3 479434.Sthe_2591 5.939e-87 301.0 COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia 189775|Thermomicrobia E FAD dependent oxidoreductase - - - - - - - - - - - - DAO DYD1_k127_4725787_1 926550.CLDAP_15280 1.15e-143 479.0 COG0793@1|root,COG3468@1|root,COG0793@2|Bacteria,COG3468@2|Bacteria,2G7PQ@200795|Chloroflexi 200795|Chloroflexi M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 DYD1_k127_4725787_2 485913.Krac_4710 7.459e-107 359.0 COG0477@1|root,COG2814@2|Bacteria,2G7RU@200795|Chloroflexi 200795|Chloroflexi EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_3 DYD1_k127_4725787_6 485913.Krac_5355 6.199e-22 99.0 COG3324@1|root,COG3324@2|Bacteria 2|Bacteria E translation initiation factor activity - - - - - - - - - - - - Glyoxalase DYD1_k127_4725787_0 903818.KI912268_gene2018 1.067e-165 540.0 COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria 57723|Acidobacteria E Peptidase family M1 domain - - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 DYD1_k127_4725787_5 1121930.AQXG01000007_gene409 1.884e-27 115.0 COG1695@1|root,COG1695@2|Bacteria,4PK5I@976|Bacteroidetes,1IZJS@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Transcriptional regulator PadR N-terminal-like - - - - - - - - - - - - PadR DYD1_k127_4766095_0 926569.ANT_23460 3.683e-100 340.0 COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi 200795|Chloroflexi D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity - - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin DYD1_k127_4772865_2 706587.Desti_4722 4.875e-62 221.0 COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria 28221|Deltaproteobacteria T carbon starvation protein CstA cstA - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM DYD1_k127_4772865_0 443144.GM21_0109 6.11e-262 832.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria 1224|Proteobacteria L DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N DYD1_k127_4772865_1 247490.KSU1_D0011 1.075e-78 271.0 COG1273@1|root,COG1273@2|Bacteria,2J4I3@203682|Planctomycetes 203682|Planctomycetes S Ku70/Ku80 beta-barrel domain - - - - - - - - - - - - Ku DYD1_k127_4772865_3 1282361.ABAC402_06505 1.981e-16 84.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UFM5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Transglycosylase-associated protein MA20_19350 - - - - - - - - - - - Transgly_assoc DYD1_k127_4775758_2 316274.Haur_0685 5.256e-17 84.0 COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia 32061|Chloroflexia O PFAM magnesium chelatase ChlI subunit - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C DYD1_k127_4775758_3 472759.Nhal_4033 4.904e-11 66.0 COG0470@1|root,COG0470@2|Bacteria,1R7PJ@1224|Proteobacteria 1224|Proteobacteria L DNA polymerase III - - - - - - - - - - - - AAA_22 DYD1_k127_4775758_0 1089550.ATTH01000001_gene2481 5.529e-121 399.0 COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1FINU@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD1_k127_4775758_1 1123504.JQKD01000004_gene5014 2.12e-83 283.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,4ACR6@80864|Comamonadaceae 28216|Betaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.31 ko:K16876 ko00365,ko01120,map00365,map01120 - R02986 RC00004,RC00174 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C DYD1_k127_4895310_5 324602.Caur_2243 2.081e-80 276.0 COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi,375I3@32061|Chloroflexia 32061|Chloroflexia S PFAM LmbE family protein - - 3.5.1.115 ko:K18455 - - - - ko00000,ko01000 - - - PIG-L DYD1_k127_4895310_0 926569.ANT_05040 4.579e-300 936.0 COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi 200795|Chloroflexi G PFAM glycosyl transferase, family 35 glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase DYD1_k127_4895310_10 593750.Metfor_0763 4.868e-30 126.0 COG4843@1|root,arCOG06902@2157|Archaea 2157|Archaea S protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179 DYD1_k127_4895310_13 1313301.AUGC01000008_gene383 7.142e-22 101.0 COG4843@1|root,COG4843@2|Bacteria,4NRH5@976|Bacteroidetes 976|Bacteroidetes S UPF0316 protein - - - - - - - - - - - - DUF2179 DYD1_k127_4895310_1 926569.ANT_06790 4.47e-111 365.0 COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4388) - - - - - - - - - - - - DUF4388 DYD1_k127_4895310_3 926569.ANT_06780 8.709e-91 301.0 COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM small GTP-binding protein - - - ko:K06945 - - - - ko00000 - - - ATP_bind_1 DYD1_k127_4895310_9 926550.CLDAP_15510 8.725e-45 174.0 COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi 200795|Chloroflexi H PFAM Thiamin pyrophosphokinase, catalytic region thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic DYD1_k127_4895310_12 1121422.AUMW01000014_gene1334 4.565e-24 108.0 COG0011@1|root,COG0011@2|Bacteria,1VBWM@1239|Firmicutes,25DPD@186801|Clostridia,262MV@186807|Peptococcaceae 186801|Clostridia S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP DYD1_k127_4895310_6 485913.Krac_8278 1.029e-67 244.0 COG0600@1|root,COG0600@2|Bacteria,2G6R1@200795|Chloroflexi 200795|Chloroflexi P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02050,ko:K15599 ko02010,map02010 M00188,M00442 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6 - - BPD_transp_1 DYD1_k127_4895310_2 383372.Rcas_0667 1.748e-97 342.0 COG0715@1|root,COG0715@2|Bacteria,2G71V@200795|Chloroflexi,376VQ@32061|Chloroflexia 32061|Chloroflexia P PFAM NMT1 THI5 like domain protein - - - - - - - - - - - - NMT1 DYD1_k127_4895310_4 1382356.JQMP01000003_gene2195 1.014e-85 301.0 COG1116@1|root,COG1116@2|Bacteria,2G6BU@200795|Chloroflexi,27YRQ@189775|Thermomicrobia 189775|Thermomicrobia P ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran DYD1_k127_4895310_11 926569.ANT_23580 3.079e-27 121.0 COG3557@1|root,COG3557@2|Bacteria,2G79G@200795|Chloroflexi 200795|Chloroflexi J Protein of unknown function (DUF402) - - - ko:K07586 - - - - ko00000 - - - DUF402 DYD1_k127_4895310_14 1045855.DSC_11355 8.188e-15 78.0 2EGCD@1|root,33A46@2|Bacteria,1NMIX@1224|Proteobacteria,1SIUN@1236|Gammaproteobacteria,1X8EM@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4190) - - - - - - - - - - - - DUF4190 DYD1_k127_4895310_7 926569.ANT_23560 7.197e-64 224.0 2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126 DYD1_k127_4895310_8 926569.ANT_23520 1.062e-58 214.0 2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi 200795|Chloroflexi S Predicted membrane protein (DUF2085) - - - - - - - - - - - - DUF2085 DYD1_k127_4926768_1 1047013.AQSP01000100_gene587 1.157e-24 121.0 COG2271@1|root,COG2271@2|Bacteria 2|Bacteria G transmembrane transporter activity - - - - - - - - - - - - MFS_1 DYD1_k127_4926768_0 401526.TcarDRAFT_1820 1.36e-211 674.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4H2IK@909932|Negativicutes 909932|Negativicutes T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_4926768_2 926550.CLDAP_12350 9.782e-07 58.0 COG3103@1|root,COG4991@2|Bacteria 2|Bacteria T sh3 domain protein - - 3.4.21.107,3.5.1.28 ko:K01448,ko:K04771 ko01503,ko02020,map01503,map02020 M00727,M00728 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110 - - - SH3_3 DYD1_k127_4974423_3 926569.ANT_06520 1.043e-81 285.0 COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi 200795|Chloroflexi IQ PFAM short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 DYD1_k127_4974423_0 926569.ANT_06500 1.023e-125 414.0 COG0111@1|root,COG0111@2|Bacteria 2|Bacteria EH 4-phosphoerythronate dehydrogenase activity - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_4974423_2 926569.ANT_06490 1.964e-82 284.0 COG1083@1|root,COG1083@2|Bacteria 2|Bacteria M cytidylyl-transferase - - 2.7.7.43 ko:K00983 ko00520,ko01100,map00520,map01100 - R01117,R04215 RC00152 ko00000,ko00001,ko01000 - - - CTP_transf_3,RraA-like DYD1_k127_4974423_1 926569.ANT_17710 6.434e-110 366.0 COG1216@1|root,COG1216@2|Bacteria,2G961@200795|Chloroflexi 200795|Chloroflexi H Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_4994415_3 926569.ANT_28940 1.032e-11 76.0 COG2382@1|root,COG2382@2|Bacteria 2|Bacteria P enterobactin catabolic process - - - ko:K07214 - - - - ko00000 - - - Esterase DYD1_k127_4994415_1 926569.ANT_23090 1.214e-43 167.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - Gmad2,LysM DYD1_k127_4994415_0 1128421.JAGA01000001_gene2365 5.305e-95 323.0 COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria 2|Bacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 DYD1_k127_4994415_2 909663.KI867150_gene2882 8.61e-12 66.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MREN@213462|Syntrophobacterales 28221|Deltaproteobacteria C TIGRFAM glutamate synthase (NADPH), homotetrameric nfnA - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2 DYD1_k127_4997695_4 391165.GbCGDNIH1_0552 3.734e-38 143.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,2JPKS@204441|Rhodospirillales 204441|Rhodospirillales J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD1_k127_4997695_2 570952.ATVH01000014_gene1983 4.717e-55 194.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2U95D@28211|Alphaproteobacteria,2JST1@204441|Rhodospirillales 204441|Rhodospirillales J Involved in the binding of tRNA to the ribosomes rpsJ - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 DYD1_k127_4997695_0 1207063.P24_12771 4.714e-110 360.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2TRHB@28211|Alphaproteobacteria,2JPA8@204441|Rhodospirillales 204441|Rhodospirillales J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 DYD1_k127_4997695_1 570967.JMLV01000010_gene1126 3.683e-80 271.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2TRUT@28211|Alphaproteobacteria,2JQ5X@204441|Rhodospirillales 204441|Rhodospirillales J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 DYD1_k127_4997695_3 1089552.KI911559_gene3014 1.306e-39 149.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2UBQ1@28211|Alphaproteobacteria,2JT6W@204441|Rhodospirillales 204441|Rhodospirillales J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 DYD1_k127_5017212_0 926569.ANT_24980 1.584e-313 985.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi 200795|Chloroflexi J phenylalanyl-tRNA synthetase beta subunit pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind DYD1_k127_5017212_1 926569.ANT_24970 2.679e-134 437.0 COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi 200795|Chloroflexi J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d DYD1_k127_5017212_5 926569.ANT_28890 1.421e-74 260.0 COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi 200795|Chloroflexi EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_5017212_6 479434.Sthe_2173 3.572e-32 140.0 COG0350@1|root,COG5662@1|root,COG0350@2|Bacteria,COG5662@2|Bacteria,2G98B@200795|Chloroflexi,27Z9T@189775|Thermomicrobia 2|Bacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated cseE - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - zf-HC2 DYD1_k127_5017212_9 479434.Sthe_2174 3.689e-21 100.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_5017212_3 926569.ANT_03400 3.384e-100 341.0 COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi 200795|Chloroflexi EGP MFS_1 like family - - - - - - - - - - - - MFS_1 DYD1_k127_5017212_8 604354.TSIB_1609 4.752e-28 124.0 COG0491@1|root,arCOG00504@2157|Archaea,2XWX3@28890|Euryarchaeota,243YZ@183968|Thermococci 183968|Thermococci S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_5017212_7 1499967.BAYZ01000159_gene478 6.574e-31 132.0 COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria 2|Bacteria S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - ko:K07025 - - - - ko00000 - - - HAD_2 DYD1_k127_5017212_2 926569.ANT_06870 8.783e-103 344.0 COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi 200795|Chloroflexi C D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_5017212_4 1123366.TH3_08909 1.52e-92 325.0 COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,2TQY1@28211|Alphaproteobacteria,2JT22@204441|Rhodospirillales 204441|Rhodospirillales C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm DYD1_k127_5017212_10 675635.Psed_3574 2.227e-07 61.0 COG2264@1|root,COG2264@2|Bacteria,2IIDT@201174|Actinobacteria,4EEW8@85010|Pseudonocardiales 201174|Actinobacteria J Methyltransferase small domain - - - - - - - - - - - - Methyltransf_25,Methyltransf_31 DYD1_k127_5018719_0 1380394.JADL01000002_gene1606 7.758e-269 840.0 COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2TRMQ@28211|Alphaproteobacteria,2JQKZ@204441|Rhodospirillales 204441|Rhodospirillales G Glycosyl hydrolases family 15 - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - Glyco_hydro_15 DYD1_k127_5018719_3 661478.OP10G_1160 1.544e-14 83.0 COG1028@1|root,COG1028@2|Bacteria 661478.OP10G_1160|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - DYD1_k127_5018719_2 211165.AJLN01000065_gene3669 1.208e-24 113.0 COG4977@1|root,COG4977@2|Bacteria,1GHSA@1117|Cyanobacteria,1JKGX@1189|Stigonemataceae 1117|Cyanobacteria K sequence-specific DNA binding - - - - - - - - - - - - - DYD1_k127_5018719_1 204669.Acid345_3728 7.532e-29 120.0 COG4566@1|root,COG4566@2|Bacteria,3Y87G@57723|Acidobacteria,2JN70@204432|Acidobacteriia 204432|Acidobacteriia T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_5031300_4 926569.ANT_15210 6.145e-86 296.0 COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi 200795|Chloroflexi KLT SMART serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase DYD1_k127_5031300_0 926569.ANT_20890 1.01e-271 848.0 COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi 200795|Chloroflexi O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD1_k127_5031300_1 1121468.AUBR01000034_gene1374 6.141e-223 704.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales 186801|Clostridia IQ PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD1_k127_5031300_2 926550.CLDAP_19050 2.372e-192 610.0 COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi 200795|Chloroflexi H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_5031300_3 926569.ANT_13300 7.074e-190 605.0 COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi 200795|Chloroflexi T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_9 DYD1_k127_5031300_5 926569.ANT_13310 9.158e-80 283.0 2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi 200795|Chloroflexi S CpXC protein - - - - - - - - - - - - CpXC DYD1_k127_5033845_14 525904.Tter_2711 2.662e-40 167.0 COG1573@1|root,COG1573@2|Bacteria 2|Bacteria L deaminated base DNA N-glycosylase activity ung - 3.2.2.27 ko:K03648,ko:K21929 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - DUF4130,UDG DYD1_k127_5033845_8 926569.ANT_14310 1.462e-107 356.0 COG0648@1|root,COG0648@2|Bacteria 2|Bacteria L deoxyribonuclease IV (phage-T4-induced) activity - - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 DYD1_k127_5033845_4 1005048.CFU_3993 1.173e-164 548.0 COG0318@1|root,COG2267@1|root,COG0318@2|Bacteria,COG2267@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,473Q4@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding DYD1_k127_5033845_10 316274.Haur_3458 7.268e-66 253.0 COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity phoR GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K02484,ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 DYD1_k127_5033845_15 926569.ANT_14320 2.065e-31 136.0 COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi 200795|Chloroflexi M PFAM diacylglycerol kinase - - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar DYD1_k127_5033845_17 1029824.AFID01000001_gene2089 1.077e-21 107.0 COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,1W9B8@1268|Micrococcaceae 201174|Actinobacteria S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 DYD1_k127_5033845_5 926569.ANT_14340 2.969e-162 540.0 COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi 200795|Chloroflexi S metal-dependent phosphohydrolase, HD sub domain - - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD DYD1_k127_5033845_13 926569.ANT_14350 1.278e-40 155.0 COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi 200795|Chloroflexi S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY DYD1_k127_5033845_21 103690.17130889 3.193e-06 59.0 COG0457@1|root,COG0457@2|Bacteria,1GHDC@1117|Cyanobacteria,1HRAS@1161|Nostocales 1117|Cyanobacteria S Anaphase-promoting complex, cyclosome, subunit 3 - - - - - - - - - - - - TPR_11,TPR_2 DYD1_k127_5033845_3 324602.Caur_2663 1.273e-165 531.0 COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,3759Q@32061|Chloroflexia 32061|Chloroflexia C PFAM acyl-CoA dehydrogenase domain protein - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_5033845_11 926550.CLDAP_15400 2.844e-52 194.0 COG2086@1|root,COG2086@2|Bacteria,2G72U@200795|Chloroflexi 200795|Chloroflexi C electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF DYD1_k127_5033845_9 926550.CLDAP_15410 8.615e-78 273.0 COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi 200795|Chloroflexi C electron transfer flavoprotein, alpha subunit - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha DYD1_k127_5033845_19 1151119.KB895497_gene3300 1.218e-10 66.0 2AFVV@1|root,33H4H@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5033845_0 485913.Krac_2178 4.677e-202 646.0 COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M3A and M3B, thimet oligopeptidase F - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N DYD1_k127_5033845_1 316274.Haur_4461 1.779e-190 609.0 COG1543@1|root,COG1543@2|Bacteria,2GBQW@200795|Chloroflexi,3764R@32061|Chloroflexia 32061|Chloroflexia G Belongs to the glycosyl hydrolase 57 family - - 2.4.1.18 ko:K16149 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000 - GH57 - DUF1957,Glyco_hydro_57 DYD1_k127_5033845_7 926569.ANT_21040 1.795e-119 399.0 COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi 200795|Chloroflexi F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 DYD1_k127_5033845_6 404589.Anae109_2966 2.812e-151 517.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales 28221|Deltaproteobacteria G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 DYD1_k127_5033845_18 926550.CLDAP_22910 5.917e-11 69.0 COG3794@1|root,COG3794@2|Bacteria 2|Bacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - Cupredoxin_1 DYD1_k127_5033845_12 383372.Rcas_2746 1.928e-41 157.0 COG0622@1|root,COG0622@2|Bacteria,2G7DJ@200795|Chloroflexi 200795|Chloroflexi S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 DYD1_k127_5033845_2 861299.J421_1510 7.087e-182 582.0 COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Amidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase DYD1_k127_5035835_7 1304872.JAGC01000009_gene980 1.455e-07 63.0 COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2X0M9@28221|Deltaproteobacteria,2MCT5@213115|Desulfovibrionales 28221|Deltaproteobacteria CO Thioredoxin domain - - - - - - - - - - - - Thioredoxin_3 DYD1_k127_5035835_0 76114.ebA6443 4.394e-196 623.0 COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VNTF@28216|Betaproteobacteria,2KVB8@206389|Rhodocyclales 206389|Rhodocyclales S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 DYD1_k127_5035835_6 324602.Caur_0013 4.936e-19 93.0 COG0640@1|root,COG0640@2|Bacteria,2GB64@200795|Chloroflexi,377ES@32061|Chloroflexia 32061|Chloroflexia K PFAM regulatory protein, ArsR - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5 DYD1_k127_5035835_5 646529.Desaci_0681 1.807e-29 124.0 COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes 1239|Firmicutes O PFAM Isoprenylcysteine carboxyl methyltransferase - - - - - - - - - - - - ICMT,PEMT DYD1_k127_5035835_2 926560.KE387028_gene161 5.157e-109 386.0 COG0428@1|root,COG0428@2|Bacteria,1WM75@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P transporter - - - - - - - - - - - - - DYD1_k127_5035835_1 266117.Rxyl_0083 6.411e-123 402.0 COG2132@1|root,COG2132@2|Bacteria,2HPY5@201174|Actinobacteria,4CRDC@84995|Rubrobacteria 84995|Rubrobacteria Q PFAM multicopper oxidase type - - - - - - - - - - - - Cu-oxidase_2,Cu-oxidase_3 DYD1_k127_5035835_3 383372.Rcas_3322 1.012e-58 211.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia 32061|Chloroflexia K iron dependent repressor - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA DYD1_k127_5035835_4 660470.Theba_0172 6.431e-36 143.0 COG1943@1|root,COG1943@2|Bacteria 2|Bacteria L Transposase - - - - - - - - - - - - Y1_Tnp DYD1_k127_5050378_6 926569.ANT_04770 2.132e-68 264.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi 200795|Chloroflexi K Transcriptional activator domain - - - - - - - - - - - - BTAD,TPR_12 DYD1_k127_5050378_8 926569.ANT_04770 3.548e-36 160.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi 200795|Chloroflexi K Transcriptional activator domain - - - - - - - - - - - - BTAD,TPR_12 DYD1_k127_5050378_2 1245475.ANAE01000162_gene2603 2.617e-136 443.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4EIFC@85012|Streptosporangiales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1079 Cys_Met_Meta_PP DYD1_k127_5050378_10 1128421.JAGA01000002_gene1413 4.311e-26 118.0 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - N6_N4_Mtase,ParBc DYD1_k127_5050378_1 1128421.JAGA01000004_gene2611 1.129e-151 494.0 COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria 2|Bacteria E Pyridoxal-phosphate dependent enzyme cysK - 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP DYD1_k127_5050378_4 525904.Tter_0425 8.229e-93 316.0 COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria 2|Bacteria S Putative esterase - - - - - - - - - - - - Esterase DYD1_k127_5050378_0 926569.ANT_14380 4.773e-152 493.0 COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi 200795|Chloroflexi E peptidase dimerisation domain protein - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD1_k127_5050378_5 926569.ANT_14370 5.99e-74 267.0 COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF1385) - - - ko:K09153 - - - - ko00000 - - - DUF1385 DYD1_k127_5050378_7 1128421.JAGA01000002_gene1190 2.553e-55 198.0 COG3059@1|root,COG3059@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - DUF417,DoxX DYD1_k127_5050378_3 316274.Haur_2447 4.183e-133 437.0 COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi,376UK@32061|Chloroflexia 32061|Chloroflexia C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_5050378_12 1304888.ATWF01000002_gene8 0.0001577 49.0 COG2104@1|root,COG2104@2|Bacteria,2GG4W@200930|Deferribacteres 200930|Deferribacteres H ThiS family - - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD1_k127_5050378_9 644966.Tmar_2076 4.53e-34 136.0 COG0037@1|root,COG0037@2|Bacteria,1UB13@1239|Firmicutes,249NH@186801|Clostridia 186801|Clostridia H Belongs to the TtcA family - - 2.8.1.15 ko:K21947 - - - - ko00000,ko01000,ko03016 - - - ATP_bind_3 DYD1_k127_5057534_4 926569.ANT_15680 3.094e-116 383.0 COG4974@1|root,COG4974@2|Bacteria,2G94T@200795|Chloroflexi 200795|Chloroflexi L Phage integrase, N-terminal SAM-like domain - - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_5057534_5 926569.ANT_31220 1.845e-93 317.0 COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi 200795|Chloroflexi T metal-dependent phosphohydrolase, HD sub domain - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5,Response_reg DYD1_k127_5057534_12 926569.ANT_31200 1.266e-45 191.0 COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA DYD1_k127_5057534_17 926569.ANT_16590 1.501e-14 79.0 29ATW@1|root,2ZXTA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5057534_13 1185653.A1A1_17785 7.763e-44 175.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,26D14@186818|Planococcaceae 91061|Bacilli M Belongs to the peptidase S41A family ctpA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 DYD1_k127_5057534_11 926569.ANT_18530 1.917e-49 181.0 COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi 200795|Chloroflexi J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB DYD1_k127_5057534_9 1499967.BAYZ01000179_gene4623 1.229e-54 202.0 29FVD@1|root,302T2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5057534_7 926569.ANT_13320 1.423e-60 217.0 COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination - - - - - - - - - - - - FHA,Guanylate_cyc,RDD,Trans_reg_C,Yop-YscD_cpl DYD1_k127_5057534_3 926569.ANT_13330 1.087e-116 385.0 COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi 200795|Chloroflexi KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase DYD1_k127_5057534_1 926569.ANT_13340 2.097e-200 656.0 COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi 200795|Chloroflexi G Glycosyl hydrolase family 3 N terminal domain - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 DYD1_k127_5057534_14 266265.Bxe_A2752 1.131e-37 158.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2VKG3@28216|Betaproteobacteria,1K3YG@119060|Burkholderiaceae 28216|Betaproteobacteria I Acyl CoA acetate 3-ketoacid CoA - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - - DYD1_k127_5057534_10 1040986.ATYO01000017_gene816 3.084e-52 196.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,43GQB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Ectoine utilization eutB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_5057534_8 926569.ANT_13360 1.287e-56 206.0 COG0584@1|root,COG0584@2|Bacteria,2G6YD@200795|Chloroflexi 200795|Chloroflexi C PFAM Glycerophosphoryl diester phosphodiesterase - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD DYD1_k127_5057534_0 926569.ANT_13370 4.206e-219 687.0 COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi 200795|Chloroflexi O SMART AAA ATPase - - - - - - - - - - - - AAA DYD1_k127_5057534_6 926569.ANT_13130 5.966e-88 326.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_5057534_2 926569.ANT_13120 8.044e-131 437.0 COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi 200795|Chloroflexi L PFAM phosphoesterase, RecJ domain protein recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD1_k127_5057534_15 926569.ANT_20810 2.361e-20 95.0 COG4818@1|root,COG4818@2|Bacteria,2G9PA@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4870) - - - - - - - - - - - - DUF4870 DYD1_k127_5057534_16 926569.ANT_20820 5.229e-20 92.0 COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi 200795|Chloroflexi J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD1_k127_5114450_1 926569.ANT_18920 8.803e-107 353.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion - - - - - - - - - - - - Band_7 DYD1_k127_5114450_0 926550.CLDAP_06400 4.53e-256 810.0 COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi 200795|Chloroflexi C Molybdopterin oxidoreductase Fe4S4 domain - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD1_k127_5114450_4 298654.FraEuI1c_3215 2.246e-05 53.0 COG2018@1|root,COG2018@2|Bacteria 2|Bacteria K Roadblock/LC7 domain - - - ko:K07131 - - - - ko00000 - - - Robl_LC7 DYD1_k127_5114450_3 1521187.JPIM01000172_gene3329 8.849e-17 94.0 COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi,375B1@32061|Chloroflexia 32061|Chloroflexia S PFAM ComEC Rec2-related protein - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 DYD1_k127_5114450_2 234267.Acid_5208 3.141e-70 244.0 COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,3Y3HP@57723|Acidobacteria 57723|Acidobacteria E TIGRFAM glutamate formiminotransferase - - 2.1.2.5,4.3.1.4 ko:K00603,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 - R02287,R02302,R03189 RC00165,RC00221,RC00223,RC00688,RC00870 ko00000,ko00001,ko01000,ko03036,ko04147 - - - FTCD,FTCD_C,FTCD_N DYD1_k127_5131899_1 926569.ANT_28860 1.61e-211 675.0 COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi 200795|Chloroflexi L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII DYD1_k127_5131899_14 1123389.ATXJ01000003_gene331 4.237e-29 121.0 COG4319@1|root,COG4319@2|Bacteria,1WJSX@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM Calcium calmodulin dependent protein kinase II - - - - - - - - - - - - CaMKII_AD DYD1_k127_5131899_5 1128421.JAGA01000002_gene1335 1.274e-142 468.0 COG0593@1|root,COG0593@2|Bacteria,2NNTK@2323|unclassified Bacteria 2|Bacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N DYD1_k127_5131899_3 926569.ANT_00970 5.876e-170 546.0 COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi 200795|Chloroflexi L DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI DYD1_k127_5131899_13 1499967.BAYZ01000156_gene549 6.813e-47 177.0 COG1418@1|root,COG1418@2|Bacteria 2|Bacteria S mRNA catabolic process - - - ko:K06950 - - - - ko00000 - - - HD DYD1_k127_5131899_0 926550.CLDAP_19360 0.0 1050.0 COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi 200795|Chloroflexi O ATPase AAA-2 domain protein clpC - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR DYD1_k127_5131899_9 926550.CLDAP_05010 5.533e-102 347.0 COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi 200795|Chloroflexi J PFAM RNA binding S1 domain protein - - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 DYD1_k127_5131899_4 926569.ANT_05380 6.738e-169 540.0 COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi 200795|Chloroflexi H introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX - - 6.6.1.1 ko:K03404,ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - AAA_5,Mg_chelatase,VWA_2 DYD1_k127_5131899_6 926569.ANT_05390 5.185e-114 376.0 COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi 200795|Chloroflexi H von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA_2 DYD1_k127_5131899_12 1125863.JAFN01000001_gene1542 1.125e-69 252.0 COG3359@1|root,COG3359@2|Bacteria,1R5KG@1224|Proteobacteria,4309C@68525|delta/epsilon subdivisions,2WVJ7@28221|Deltaproteobacteria 28221|Deltaproteobacteria L RNase_H superfamily - - - ko:K07502 - - - - ko00000 - - - RNase_H_2 DYD1_k127_5131899_2 926569.ANT_28000 2.28e-183 594.0 COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi 200795|Chloroflexi T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,Response_reg DYD1_k127_5131899_11 926569.ANT_27990 2.338e-96 329.0 COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria 926569.ANT_27990|- T PhoQ Sensor - - - - - - - - - - - - - DYD1_k127_5131899_7 926569.ANT_25840 4.848e-105 349.0 COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi 200795|Chloroflexi O Heat shock protein DnaJ domain protein - - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C DYD1_k127_5131899_8 926569.ANT_25850 3.735e-102 349.0 COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase S1 and S6, chymotrypsin Hap - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_5131899_10 926569.ANT_25860 1.099e-96 328.0 COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi 200795|Chloroflexi J translation release factor activity - - - ko:K03265 ko03015,map03015 - - - ko00000,ko00001,ko03012,ko03019 - - - eRF1_2,eRF1_3 DYD1_k127_5138756_3 1335760.ASTG01000017_gene3460 0.0001942 49.0 2C1UQ@1|root,33VUD@2|Bacteria,1RM45@1224|Proteobacteria,2UBKR@28211|Alphaproteobacteria,2K9TG@204457|Sphingomonadales 204457|Sphingomonadales S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_5138756_0 926569.ANT_29360 2.093e-132 438.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi 200795|Chloroflexi M PFAM sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 DYD1_k127_5138756_2 1123368.AUIS01000003_gene1679 1.445e-74 255.0 COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,2NCIQ@225057|Acidithiobacillales 225057|Acidithiobacillales G Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose - - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom DYD1_k127_5138756_1 926569.ANT_29340 2.092e-97 322.0 COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi 200795|Chloroflexi M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rmlB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD1_k127_5152456_0 926569.ANT_20420 1.112e-199 644.0 COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi 200795|Chloroflexi L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF DYD1_k127_5152456_7 926569.ANT_20430 3.957e-57 207.0 COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi 200795|Chloroflexi J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro DYD1_k127_5152456_12 926569.ANT_20440 1.056e-10 71.0 COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi 200795|Chloroflexi S ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - - DYD1_k127_5152456_10 926569.ANT_14790 1.444e-36 147.0 COG1825@1|root,COG1825@2|Bacteria,2G7A4@200795|Chloroflexi 200795|Chloroflexi J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C DYD1_k127_5152456_9 1123401.JHYQ01000038_gene1601 8.06e-42 164.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L NUDIX hydrolase nudL GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - - - - - - - - - - DUF1289,NUDIX DYD1_k127_5152456_4 926569.ANT_14770 3.355e-77 267.0 COG2519@1|root,COG2519@2|Bacteria,2G8GD@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - 2.1.1.219,2.1.1.220 ko:K07442 - - - - ko00000,ko01000,ko03016 - - - GCD14 DYD1_k127_5152456_11 383372.Rcas_2562 1.182e-27 122.0 COG0500@1|root,COG2226@2|Bacteria,2G724@200795|Chloroflexi,377H0@32061|Chloroflexia 32061|Chloroflexia H Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 DYD1_k127_5152456_5 555088.DealDRAFT_2880 1.119e-74 260.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes 1239|Firmicutes I Lipid kinase - - - - - - - - - - - - DAGK_cat DYD1_k127_5152456_2 383372.Rcas_2520 1.614e-103 354.0 COG2239@1|root,COG2239@2|Bacteria,2G6H7@200795|Chloroflexi,376RI@32061|Chloroflexia 32061|Chloroflexia P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD1_k127_5152456_13 1307759.JOMJ01000003_gene915 2.137e-07 58.0 COG1148@1|root,COG1148@2|Bacteria,1QV9V@1224|Proteobacteria,42SKG@68525|delta/epsilon subdivisions,2WP8G@28221|Deltaproteobacteria,2MBB5@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM NIL domain - - - - - - - - - - - - Fer4,Fer4_4,Fer4_7,NIL DYD1_k127_5152456_3 479434.Sthe_2188 6.287e-93 317.0 COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase S1 and S6, chymotrypsin Hap - - 1.3.1.74 ko:K08070 - - - - ko00000,ko01000 - - - PDZ_2,Trypsin_2 DYD1_k127_5152456_6 194439.CT0786 2.441e-57 207.0 COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi 1090|Chlorobi S PFAM peptidase, membrane zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 DYD1_k127_5152456_1 926569.ANT_12940 4.957e-131 430.0 COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi 200795|Chloroflexi M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 DYD1_k127_5152456_8 266265.Bxe_A2751 1.468e-53 200.0 COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2VK8V@28216|Betaproteobacteria,1K1J7@119060|Burkholderiaceae 28216|Betaproteobacteria I Coenzyme A transferase gctA - 2.8.3.12,2.8.3.5 ko:K01028,ko:K01039 ko00072,ko00280,ko00643,ko00650,ko01120,map00072,map00280,map00643,map00650,map01120 - R00410,R04000,R05509 RC00012,RC00014,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD1_k127_5155595_2 635013.TherJR_2465 2.34e-170 555.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,249N1@186801|Clostridia,260S4@186807|Peptococcaceae 186801|Clostridia E amino acid - - - - - - - - - - - - AA_permease_2 DYD1_k127_5155595_3 926550.CLDAP_27570 1.992e-135 441.0 COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi 200795|Chloroflexi C PFAM acyl-CoA dehydrogenase domain protein - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_5155595_0 518766.Rmar_1427 2.286e-257 808.0 COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1FIMS@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes I AMP-binding enzyme C-terminal domain - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD1_k127_5155595_22 485913.Krac_2737 1.094e-06 62.0 2E8GM@1|root,332UW@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5155595_13 671143.DAMO_0654 4.127e-53 197.0 COG1545@1|root,COG1545@2|Bacteria 2|Bacteria I DUF35 OB-fold domain, acyl-CoA-associated - - - ko:K07068 - - - - ko00000 - - - DUF35_N,OB_aCoA_assoc DYD1_k127_5155595_1 671143.DAMO_0652 2.344e-219 688.0 COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD1_k127_5155595_11 926569.ANT_15050 2.041e-60 218.0 COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi 200795|Chloroflexi U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC DYD1_k127_5155595_23 383372.Rcas_3257 5.698e-05 53.0 COG1826@1|root,COG1826@2|Bacteria,2G7D4@200795|Chloroflexi,377TB@32061|Chloroflexia 32061|Chloroflexia U PFAM sec-independent translocation protein mttA Hcf106 - - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD1_k127_5155595_15 926569.ANT_14610 1.644e-35 141.0 COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi 200795|Chloroflexi K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB DYD1_k127_5155595_18 926569.ANT_14620 7.767e-26 115.0 COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi 200795|Chloroflexi S Asp23 family, cell envelope-related function - - - - - - - - - - - - Asp23 DYD1_k127_5155595_7 1122216.AUHW01000012_gene1550 2.71e-82 280.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes 909932|Negativicutes IQ reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_5155595_10 926569.ANT_20830 1.103e-64 234.0 COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C DYD1_k127_5155595_6 926569.ANT_13970 3.035e-86 296.0 COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi 200795|Chloroflexi K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc DYD1_k127_5155595_5 926569.ANT_13980 1.233e-102 342.0 COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi 200795|Chloroflexi D PFAM Cobyrinic acid a,c-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD1_k127_5155595_8 926569.ANT_13990 1.421e-77 271.0 COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi 200795|Chloroflexi G PFAM PfkB domain protein - - - - - - - - - - - - PfkB DYD1_k127_5155595_12 926569.ANT_22890 6.667e-60 216.0 COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi 200795|Chloroflexi S PFAM single-stranded nucleic acid binding R3H domain protein - - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H DYD1_k127_5155595_9 926569.ANT_22900 5.666e-71 251.0 COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi 200795|Chloroflexi U PFAM 60 kDa inner membrane insertion protein - - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP DYD1_k127_5155595_16 485914.Hmuk_0677 2.304e-30 135.0 COG1520@1|root,arCOG02556@2157|Archaea,2Y7Q9@28890|Euryarchaeota,240XC@183963|Halobacteria 183963|Halobacteria C PQQ-like domain - - - - - - - - - - - - PQQ_2,PQQ_3 DYD1_k127_5155595_17 926569.ANT_22920 8.91e-27 115.0 COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi 200795|Chloroflexi S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic DYD1_k127_5155595_20 316274.Haur_0766 1.247e-16 83.0 COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi,375ZH@32061|Chloroflexia 32061|Chloroflexia J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P DYD1_k127_5155595_21 926569.ANT_22940 4.175e-14 73.0 COG0230@1|root,COG0230@2|Bacteria 2|Bacteria J Ribosomal protein L34 rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 DYD1_k127_5155595_14 411468.CLOSCI_01924 9.422e-50 190.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,21Y22@1506553|Lachnoclostridium 186801|Clostridia D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD1_k127_5155595_19 469383.Cwoe_3534 3.866e-19 87.0 COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria 84995|Rubrobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase DYD1_k127_5165240_0 926569.ANT_16850 7.231e-137 466.0 29DKV@1|root,300IP@2|Bacteria,2G8H2@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_5167903_3 1128421.JAGA01000003_gene3461 1.046e-124 413.0 COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria 2|Bacteria C Belongs to the citrate synthase family citA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD1_k127_5167903_13 290315.Clim_1318 3.578e-80 279.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - - - - - - - - - - - FHA,Trypsin,Trypsin_2 DYD1_k127_5167903_25 1385518.N798_10560 1.07e-11 69.0 COG0265@1|root,COG0265@2|Bacteria,2ICC4@201174|Actinobacteria,4FI5B@85021|Intrasporangiaceae 201174|Actinobacteria O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - - - - - - - - - - - DYD1_k127_5167903_28 1396418.BATQ01000181_gene833 0.000178 53.0 COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia 74201|Verrucomicrobia OU PA domain - - - - - - - - - - - - PA,PD40,PDZ_2,Peptidase_M28 DYD1_k127_5167903_8 926569.ANT_00470 1.401e-95 319.0 COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi 200795|Chloroflexi Q PFAM Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11 DYD1_k127_5167903_26 1206731.BAGB01000171_gene4677 6.457e-09 64.0 COG3787@1|root,COG3787@2|Bacteria,2IHVY@201174|Actinobacteria 201174|Actinobacteria S Belongs to the UPF0306 family - - - ko:K09979 - - - - ko00000 - - - Putative_PNPOx,Pyridox_ox_2 DYD1_k127_5167903_22 1121033.AUCF01000001_gene2246 1.057e-36 145.0 COG0494@1|root,COG0494@2|Bacteria,1N11E@1224|Proteobacteria,2U9YU@28211|Alphaproteobacteria,2JUSE@204441|Rhodospirillales 204441|Rhodospirillales L NUDIX domain - - - - - - - - - - - - NUDIX DYD1_k127_5167903_17 1247024.JRLH01000002_gene153 2.391e-57 216.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2311,iAPECO1_1312.APECO1_4253,iB21_1397.B21_02196,iBWG_1329.BWG_2085,iE2348C_1286.E2348C_2451,iEC55989_1330.EC55989_2555,iECBD_1354.ECBD_1348,iECB_1328.ECB_02236,iECDH10B_1368.ECDH10B_2473,iECDH1ME8569_1439.ECDH1ME8569_2249,iECD_1391.ECD_02236,iECED1_1282.ECED1_2775,iECH74115_1262.ECH74115_3451,iECIAI39_1322.ECIAI39_2460,iECNA114_1301.ECNA114_2401,iECO103_1326.ECO103_2775,iECOK1_1307.ECOK1_2544,iECP_1309.ECP_2350,iECS88_1305.ECS88_2458,iECSE_1348.ECSE_2620,iECSF_1327.ECSF_2187,iECSP_1301.ECSP_3186,iECs_1301.ECs3195,iETEC_1333.ETEC_2447,iEcDH1_1363.EcDH1_1345,iEcE24377_1341.EcE24377A_2605,iEcHS_1320.EcHS_A2462,iEcSMS35_1347.EcSMS35_2467,iG2583_1286.G2583_2848,iJO1366.b2311,iJR904.b2311,iLF82_1304.LF82_2354,iNRG857_1313.NRG857_11705,iSDY_1059.SDY_2510,iUMN146_1321.UM146_05255,iUMNK88_1353.UMNK88_2862,iUTI89_1310.UTI89_C2595,iY75_1357.Y75_RS12120,iZ_1308.Z3573 Flavoprotein DYD1_k127_5167903_16 926569.ANT_24730 1.014e-62 223.0 COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi 200795|Chloroflexi H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran DYD1_k127_5167903_6 926569.ANT_03730 3.369e-98 333.0 COG0600@1|root,COG0600@2|Bacteria,2G72A@200795|Chloroflexi 200795|Chloroflexi P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_5167903_9 926569.ANT_03740 3.457e-94 320.0 COG1116@1|root,COG1116@2|Bacteria,2G8SU@200795|Chloroflexi 200795|Chloroflexi P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_5167903_14 926569.ANT_03750 1.958e-73 259.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process ssuA - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_5167903_15 134676.ACPL_412 3.55e-71 270.0 COG0382@1|root,COG0382@2|Bacteria,2GJJ7@201174|Actinobacteria,4D9WH@85008|Micromonosporales 201174|Actinobacteria H 4-hydroxybenzoate polyprenyltransferase ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD1_k127_5167903_12 324602.Caur_1591 7.143e-81 284.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily ydeG - - - - - - - - - - - MFS_1,Sugar_tr DYD1_k127_5167903_2 926550.CLDAP_08640 2.973e-136 445.0 COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - - - - - - - - - - - DUF2920,FecR,LysM,Peptidase_S9 DYD1_k127_5167903_7 316274.Haur_4136 6.439e-98 331.0 COG0412@1|root,COG0412@2|Bacteria,2G868@200795|Chloroflexi,37610@32061|Chloroflexia 32061|Chloroflexia Q PFAM dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_5167903_23 1356852.N008_13810 5.671e-34 147.0 COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,47PX0@768503|Cytophagia 976|Bacteroidetes S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA DYD1_k127_5167903_11 880072.Desac_2549 9.265e-86 291.0 COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_25 DYD1_k127_5167903_18 1499967.BAYZ01000120_gene3420 7.89e-55 200.0 COG2020@1|root,COG2020@2|Bacteria,2NR07@2323|unclassified Bacteria 2|Bacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - PEMT DYD1_k127_5167903_10 324602.Caur_2791 1.531e-90 308.0 COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi,375QT@32061|Chloroflexia 32061|Chloroflexia C PFAM Glyoxalase bleomycin resistance protein dioxygenase - - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase DYD1_k127_5167903_0 706587.Desti_0324 3.139e-207 654.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2MQ8V@213462|Syntrophobacterales 28221|Deltaproteobacteria H Belongs to the UbiD family - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_5167903_1 595460.RRSWK_00040 1.257e-151 496.0 COG0364@1|root,COG0364@2|Bacteria,2IXCV@203682|Planctomycetes 203682|Planctomycetes G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N DYD1_k127_5167903_5 926569.ANT_19820 5.017e-113 378.0 COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi 200795|Chloroflexi S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 DYD1_k127_5167903_21 379066.GAU_3352 1.393e-43 164.0 COG1528@1|root,COG1528@2|Bacteria,1ZUFX@142182|Gemmatimonadetes 142182|Gemmatimonadetes P Rubrerythrin - - 1.16.3.1 ko:K22336 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin DYD1_k127_5167903_19 518766.Rmar_0288 1.074e-45 185.0 COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,4NI98@976|Bacteroidetes 976|Bacteroidetes KT Serine phosphatase RsbU regulator of sigma subunit - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - SpoIIE DYD1_k127_5167903_4 926569.ANT_12750 3.813e-119 394.0 COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi 200795|Chloroflexi S SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - HHH_3,Radical_SAM DYD1_k127_5175174_2 388467.A19Y_1140 2.703e-07 55.0 2997Q@1|root,2ZWAZ@2|Bacteria,1GG7V@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5175174_0 1094508.Tsac_2301 2.637e-104 349.0 COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,248Q3@186801|Clostridia 186801|Clostridia G PFAM Glycoside hydrolase 15-related - - - - - - - - - - - - Glyco_hydro_15 DYD1_k127_5175174_1 44251.PDUR_12335 1.451e-84 300.0 COG5297@1|root,COG5297@2|Bacteria,1UZ72@1239|Firmicutes,4HTY6@91061|Bacilli,26VE2@186822|Paenibacillaceae 91061|Bacilli G Glycosyl hydrolase family 66 - - 3.2.1.11 ko:K05988 ko00500,map00500 - R11309 - ko00000,ko00001,ko01000 - GH66 - Glyco_hydro_66 DYD1_k127_5198168_1 926569.ANT_13390 1.896e-96 319.0 COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi 200795|Chloroflexi F PFAM deoxynucleoside kinase - - - - - - - - - - - - dNK DYD1_k127_5198168_0 926569.ANT_23480 0.0 1149.0 COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD DYD1_k127_5198168_2 926569.ANT_23470 8.126e-62 218.0 COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi 200795|Chloroflexi K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone DYD1_k127_5220101_6 926569.ANT_11620 1.513e-57 212.0 COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi 200795|Chloroflexi L Methyltransferase - - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 DYD1_k127_5220101_4 926569.ANT_11630 5.714e-100 344.0 COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi 200795|Chloroflexi H PFAM Uroporphyrinogen decarboxylase (URO-D) - - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D DYD1_k127_5220101_9 926569.ANT_11640 2.11e-13 76.0 COG0457@1|root,COG0457@2|Bacteria 926569.ANT_11640|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_5220101_3 926569.ANT_20570 1.219e-133 434.0 COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi 200795|Chloroflexi C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA DYD1_k127_5220101_0 926569.ANT_20580 1.67e-165 530.0 COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi 200795|Chloroflexi F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA DYD1_k127_5220101_5 926569.ANT_11710 1.402e-74 267.0 COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi 200795|Chloroflexi J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.20,5.4.99.22 ko:K06178,ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_5220101_7 926569.ANT_11700 8.005e-50 185.0 COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi 200795|Chloroflexi D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB DYD1_k127_5220101_2 926569.ANT_11680 8.623e-135 451.0 COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria 2|Bacteria S pathogenesis - - - ko:K21471,ko:K21687 - - - - ko00000,ko01000,ko01002,ko01011 - GH23 - G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal DYD1_k127_5220101_1 926569.ANT_11670 2.827e-150 482.0 COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi 200795|Chloroflexi M PFAM NAD-dependent epimerase dehydratase - - 4.1.1.35,4.2.1.46 ko:K01710,ko:K08678 ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00793 R01384,R06513 RC00402,RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD1_k127_5220101_8 926569.ANT_11660 3.869e-38 155.0 COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi 200795|Chloroflexi S GtrA-like protein - - - - - - - - - - - - GtrA DYD1_k127_5242970_1 926569.ANT_02860 3.651e-66 242.0 COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi 200795|Chloroflexi L 3'-5' exonuclease - - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC DYD1_k127_5242970_3 926550.CLDAP_20100 7.417e-34 143.0 COG0723@1|root,COG0723@2|Bacteria,2G7BG@200795|Chloroflexi 200795|Chloroflexi C Rieske [2Fe-2S] domain - - 1.10.9.1 ko:K02636 ko00195,ko01100,map00195,map01100 M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske DYD1_k127_5242970_0 926550.CLDAP_20090 1.02e-158 516.0 COG1290@1|root,COG1290@2|Bacteria 2|Bacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - - - - - - - - - iAF987.Gmet_3585 Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B DYD1_k127_5242970_2 926550.CLDAP_20080 3.963e-39 156.0 COG2010@1|root,COG2010@2|Bacteria,2G9TS@200795|Chloroflexi 2|Bacteria C Cytochrome c - - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Cytochrom_C,Cytochrome_CBB3 DYD1_k127_5247265_0 404589.Anae109_2774 3.351e-27 116.0 COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales 28221|Deltaproteobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD1_k127_5247265_1 1408418.JNJH01000052_gene3530 3.325e-05 57.0 COG4485@1|root,COG4485@2|Bacteria,1QGV0@1224|Proteobacteria 1224|Proteobacteria S polysaccharide biosynthetic process - - - - - - - - - - - - - DYD1_k127_5263381_9 909663.KI867149_gene3387 5.678e-81 275.0 COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MR44@213462|Syntrophobacterales 28221|Deltaproteobacteria S SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc DYD1_k127_5263381_20 926569.ANT_03760 1.031e-49 180.0 COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi 200795|Chloroflexi S PFAM Roadblock LC7 family protein - - - ko:K07131 - - - - ko00000 - - - Robl_LC7 DYD1_k127_5263381_28 926569.ANT_03770 3.275e-22 105.0 COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi 200795|Chloroflexi S 4-vinyl reductase, 4VR - - - - - - - - - - - - V4R DYD1_k127_5263381_5 926569.ANT_03790 3.815e-91 306.0 COG0463@1|root,COG0463@2|Bacteria,2GBP0@200795|Chloroflexi 200795|Chloroflexi M Glycosyltransferase like family 2 - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 DYD1_k127_5263381_11 926569.ANT_03800 9.022e-78 271.0 COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi 200795|Chloroflexi J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD DYD1_k127_5263381_24 926569.ANT_07860 6.89e-26 120.0 COG1316@1|root,COG1316@2|Bacteria 2|Bacteria K TRANSCRIPTIONal - - - - - - - - - - - - LytR_C,LytR_cpsA_psr DYD1_k127_5263381_21 608506.COB47_0417 5.126e-48 186.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,42FNK@68295|Thermoanaerobacterales 186801|Clostridia M TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - - - - - - - - - - Bac_transf DYD1_k127_5263381_30 530564.Psta_3840 1.018e-14 87.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - - DYD1_k127_5263381_3 926569.ANT_03810 1.151e-103 355.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF348) - - - - - - - - - - - - DUF348,G5 DYD1_k127_5263381_22 1122221.JHVI01000007_gene2245 3.127e-36 151.0 COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD1_k127_5263381_14 1540221.JQNI01000002_gene1867 7.286e-70 243.0 COG0739@1|root,COG0739@2|Bacteria 2|Bacteria M heme binding - - - - - - - - - - - - Peptidase_M23 DYD1_k127_5263381_2 926569.ANT_05370 7.967e-174 561.0 COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi 200795|Chloroflexi G PFAM glycoside hydrolase, family 1 - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 DYD1_k127_5263381_32 479434.Sthe_0162 3.193e-13 82.0 COG1404@1|root,COG1404@2|Bacteria,2G7HM@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - ko:K17734 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S8 DYD1_k127_5263381_26 926550.CLDAP_03010 8.862e-24 113.0 COG1388@1|root,COG1388@2|Bacteria,2G9RQ@200795|Chloroflexi 200795|Chloroflexi M Lysin motif - - - - - - - - - - - - LysM DYD1_k127_5263381_15 926569.ANT_03580 7.454e-69 256.0 COG0457@1|root,COG0457@2|Bacteria 926569.ANT_03580|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_5263381_18 926569.ANT_12120 4.279e-56 211.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1 DYD1_k127_5263381_31 926569.ANT_13230 2e-14 76.0 COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi 200795|Chloroflexi J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p DYD1_k127_5263381_1 926569.ANT_13220 8.029e-175 567.0 COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi 200795|Chloroflexi J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d DYD1_k127_5263381_0 926569.ANT_13210 8.646e-214 671.0 COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi 200795|Chloroflexi S cyclic 2,3-diphosphoglycerate synthetase activity - - - - - - - - - - - - - DYD1_k127_5263381_10 1128421.JAGA01000002_gene1836 3.904e-80 283.0 COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria 2|Bacteria L PFAM DNA methylase N-4 N-6 - - 2.1.1.72 ko:K00571,ko:K07316 - - - - ko00000,ko01000,ko02048 - - - Mrr_cat,N6_N4_Mtase DYD1_k127_5263381_19 926569.ANT_06810 3.915e-51 189.0 COG0745@1|root,COG0745@2|Bacteria 926569.ANT_06810|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_5263381_29 926560.KE387023_gene2608 4.73e-20 94.0 COG3478@1|root,COG3478@2|Bacteria 2|Bacteria S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) ypzJ - - ko:K07069 - - - - ko00000 - - - zinc_ribbon_13 DYD1_k127_5263381_13 1121945.ATXS01000007_gene506 8.101e-72 271.0 COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria 183963|Halobacteria G Melibiase - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Melibiase DYD1_k127_5263381_4 926569.ANT_10880 1.513e-91 315.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - CHAP,DUF1906,PG_binding_1,Peptidase_M15_4 DYD1_k127_5263381_7 1121406.JAEX01000007_gene2388 1.14e-87 303.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2M80Z@213115|Desulfovibrionales 28221|Deltaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH DYD1_k127_5263381_6 926569.ANT_14180 2.391e-90 316.0 COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi 200795|Chloroflexi J PFAM Polynucleotide adenylyltransferase region - - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 DYD1_k127_5263381_12 926569.ANT_14170 5.156e-73 254.0 COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi 200795|Chloroflexi F Belongs to the purine pyrimidine phosphoribosyltransferase family - - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran DYD1_k127_5263381_8 926569.ANT_14160 4.077e-82 277.0 COG1435@1|root,COG1435@2|Bacteria,2G6DP@200795|Chloroflexi 200795|Chloroflexi F PFAM thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK DYD1_k127_5263381_17 926569.ANT_25140 4.465e-57 203.0 COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi 200795|Chloroflexi J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 DYD1_k127_5263381_23 926569.ANT_25130 1.105e-30 122.0 COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi 200795|Chloroflexi J Ribosomal L27 protein rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 DYD1_k127_5263381_27 525904.Tter_0488 2.165e-23 107.0 COG0261@1|root,COG0261@2|Bacteria,2NPSX@2323|unclassified Bacteria 2|Bacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p DYD1_k127_5268401_2 926569.ANT_24700 1.13e-120 397.0 COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi 200795|Chloroflexi J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C DYD1_k127_5268401_0 926569.ANT_03460 5.536e-221 707.0 COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M3A and M3B, thimet oligopeptidase F - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N DYD1_k127_5268401_4 234621.RER_42070 5.226e-50 183.0 COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4G18G@85025|Nocardiaceae 201174|Actinobacteria S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt DYD1_k127_5268401_5 997296.PB1_11549 3.513e-43 163.0 COG4538@1|root,COG4538@2|Bacteria,1V7Q1@1239|Firmicutes,4HJ77@91061|Bacilli,1ZHEN@1386|Bacillus 91061|Bacilli S SnoaL-like domain - - - - - - - - - - - - DUF4440,SnoaL_3 DYD1_k127_5268401_3 446468.Ndas_0580 2.576e-53 206.0 COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4EIFG@85012|Streptosporangiales 201174|Actinobacteria M Glycosyl transferase 4-like - - 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 DYD1_k127_5268401_9 378806.STAUR_7037 6.824e-09 66.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2YWC5@29|Myxococcales 28221|Deltaproteobacteria I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_5268401_1 926569.ANT_02850 2.88e-168 542.0 COG1236@1|root,COG1236@2|Bacteria,2G62G@200795|Chloroflexi 200795|Chloroflexi J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL DYD1_k127_5268401_8 926569.ANT_02860 1.388e-10 65.0 COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi 200795|Chloroflexi L 3'-5' exonuclease - - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC DYD1_k127_5279283_1 1489678.RDMS_00915 7.88e-09 59.0 COG3335@1|root,COG3335@2|Bacteria 2|Bacteria L DDE superfamily endonuclease - - - ko:K07494 - - - - ko00000 - - - DDE_3,HTH_33 DYD1_k127_5279283_0 525897.Dbac_1433 4.839e-125 413.0 COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,42M93@68525|delta/epsilon subdivisions,2WK5I@28221|Deltaproteobacteria,2M9GS@213115|Desulfovibrionales 28221|Deltaproteobacteria L PFAM Transposase, IS204 IS1001 IS1096 IS1165 - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 DYD1_k127_5284906_2 324602.Caur_1864 0.0009593 44.0 COG3023@1|root,COG4288@1|root,COG3023@2|Bacteria,COG4288@2|Bacteria,2G8VN@200795|Chloroflexi,375C9@32061|Chloroflexia 32061|Chloroflexia V PFAM N-acetylmuramoyl-L-alanine amidase, family 2 - - - - - - - - - - - - Amidase_2 DYD1_k127_5284906_0 349521.HCH_03065 9.163e-39 165.0 COG0739@1|root,COG0739@2|Bacteria,1R6RZ@1224|Proteobacteria,1RP73@1236|Gammaproteobacteria,1XNPW@135619|Oceanospirillales 135619|Oceanospirillales M Peptidase family M23 - - - ko:K08642 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002 - - - PPC,Peptidase_M23 DYD1_k127_5284906_1 1121104.AQXH01000001_gene1402 2.203e-34 151.0 COG3266@1|root,COG3266@2|Bacteria 2|Bacteria GM domain, Protein - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Laminin_G_3,Pkinase DYD1_k127_5293849_39 1382306.JNIM01000001_gene758 1.286e-38 155.0 COG0697@1|root,COG0697@2|Bacteria,2G8R9@200795|Chloroflexi 200795|Chloroflexi EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_5293849_2 635013.TherJR_0057 1.223e-184 590.0 COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae 186801|Clostridia H Trimethylamine methyltransferase - - 2.1.1.250 ko:K14083 ko00680,ko01120,ko01200,map00680,map01120,map01200 M00563 R09124,R10016 RC00035,RC00732,RC01144,RC02984 ko00000,ko00001,ko00002,ko01000 - - - MTTB DYD1_k127_5293849_38 1382356.JQMP01000003_gene1709 3.003e-39 157.0 COG2188@1|root,COG2188@2|Bacteria,2GBGB@200795|Chloroflexi,27Z9U@189775|Thermomicrobia 189775|Thermomicrobia K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA DYD1_k127_5293849_26 696369.KI912183_gene2010 7.767e-72 252.0 COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,24G1T@186801|Clostridia 186801|Clostridia S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest DYD1_k127_5293849_25 485915.Dret_2263 2.415e-72 254.0 COG1284@1|root,COG1284@2|Bacteria,1R59F@1224|Proteobacteria,42P6M@68525|delta/epsilon subdivisions,2WKCS@28221|Deltaproteobacteria,2MA8Q@213115|Desulfovibrionales 28221|Deltaproteobacteria S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane DYD1_k127_5293849_5 926569.ANT_31300 4.85e-144 465.0 COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi 200795|Chloroflexi P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - ko:K02052 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - ABC_tran,TOBE_2 DYD1_k127_5293849_18 948106.AWZT01000039_gene1120 9.54e-87 309.0 COG1177@1|root,COG1177@2|Bacteria,1MV4A@1224|Proteobacteria,2VMSC@28216|Betaproteobacteria,1K3MI@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 DYD1_k127_5293849_11 926569.ANT_31320 2.864e-111 368.0 COG4132@1|root,COG4132@2|Bacteria,2G69Y@200795|Chloroflexi 200795|Chloroflexi P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 DYD1_k127_5293849_9 511051.CSE_14440 3.325e-123 406.0 COG1840@1|root,COG1840@2|Bacteria 2|Bacteria P iron ion homeostasis - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6 DYD1_k127_5293849_3 1128421.JAGA01000003_gene3664 2.644e-165 541.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid steT - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease,AA_permease_2 DYD1_k127_5293849_12 1128421.JAGA01000003_gene3665 4.931e-108 358.0 COG2129@1|root,COG2129@2|Bacteria 2|Bacteria L metallophosphoesterase - - - ko:K07096,ko:K07496 - - - - ko00000 - - - Metallophos,Metallophos_2,Metallophos_3 DYD1_k127_5293849_21 926569.ANT_00170 1.143e-78 276.0 COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi 200795|Chloroflexi L FES - - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD DYD1_k127_5293849_47 1047013.AQSP01000111_gene1661 1.387e-11 72.0 COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria 2|Bacteria O peptidase U32 yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C DYD1_k127_5293849_33 1173024.KI912151_gene1714 7.346e-49 193.0 COG0642@1|root,COG0784@1|root,COG2204@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg DYD1_k127_5293849_37 1380390.JIAT01000009_gene1835 1.039e-40 157.0 COG1670@1|root,COG1670@2|Bacteria,2IFNY@201174|Actinobacteria 2|Bacteria J Acetyltransferases including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 DYD1_k127_5293849_10 926569.ANT_27130 5.304e-121 402.0 COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi 200795|Chloroflexi L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 DYD1_k127_5293849_0 926569.ANT_27120 1.496e-225 722.0 COG0574@1|root,COG0574@2|Bacteria 2|Bacteria G Belongs to the PEP-utilizing enzyme family - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PPDK_N DYD1_k127_5293849_28 368407.Memar_2225 2.615e-68 238.0 COG2518@1|root,arCOG00976@2157|Archaea,2XTRM@28890|Euryarchaeota,2N9U4@224756|Methanomicrobia 224756|Methanomicrobia J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD1_k127_5293849_20 452637.Oter_0998 3.321e-82 282.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - - - - - - - - - - EamA DYD1_k127_5293849_15 926569.ANT_24710 6.456e-104 341.0 COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi 200795|Chloroflexi S PFAM oxidoreductase, molybdopterin binding - - - - - - - - - - - - Oxidored_molyb DYD1_k127_5293849_14 1379698.RBG1_1C00001G0415 3.907e-107 364.0 COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 DYD1_k127_5293849_46 335543.Sfum_3227 5.152e-14 77.0 COG4244@1|root,COG4892@1|root,COG4244@2|Bacteria,COG4892@2|Bacteria,1N3DP@1224|Proteobacteria,42U1X@68525|delta/epsilon subdivisions,2WQFI@28221|Deltaproteobacteria,2MRX2@213462|Syntrophobacterales 28221|Deltaproteobacteria S Cytochrome b5-like Heme/Steroid binding domain - - - - - - - - - - - - CopD,Cyt-b5 DYD1_k127_5293849_19 1121377.KB906415_gene4061 1.865e-85 301.0 COG2021@1|root,COG2021@2|Bacteria 2|Bacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 DYD1_k127_5293849_24 926569.ANT_00640 1.2e-74 256.0 COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi 200795|Chloroflexi F Phosphoribosyl transferase domain - - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran DYD1_k127_5293849_31 926569.ANT_16060 2.233e-52 190.0 COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi 200795|Chloroflexi K regulatory protein, arsR - - - - - - - - - - - - DUF2087,HTH_5 DYD1_k127_5293849_16 926569.ANT_27790 1.257e-101 339.0 COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi 200795|Chloroflexi Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 DYD1_k127_5293849_34 324602.Caur_0271 2.457e-46 184.0 COG1668@1|root,COG1668@2|Bacteria,2G76A@200795|Chloroflexi,3777A@32061|Chloroflexia 32061|Chloroflexia CP ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_2 DYD1_k127_5293849_13 351160.LRC208 2.087e-107 359.0 COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N95K@224756|Methanomicrobia 224756|Methanomicrobia V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5293849_35 1254432.SCE1572_36870 8.948e-46 177.0 COG4377@1|root,COG4377@2|Bacteria,1QACG@1224|Proteobacteria,43DZN@68525|delta/epsilon subdivisions,2WZAB@28221|Deltaproteobacteria,2Z1PM@29|Myxococcales 28221|Deltaproteobacteria S Putative membrane peptidase family (DUF2324) - - - - - - - - - - - - DUF2324 DYD1_k127_5293849_49 1445613.JALM01000009_gene653 2.854e-10 69.0 arCOG12598@1|root,2ZACP@2|Bacteria,2IJWA@201174|Actinobacteria,4EAZ0@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - SpoIIM DYD1_k127_5293849_51 1196028.ALEF01000001_gene1906 9.54e-08 62.0 COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HEAP@91061|Bacilli 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component yxlG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_5 DYD1_k127_5293849_27 255470.cbdbA1715 1.004e-70 252.0 COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,34CZ8@301297|Dehalococcoidia 301297|Dehalococcoidia V Domain of unknown function (DUF4162) - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 DYD1_k127_5293849_45 1131730.BAVI_15446 1.071e-16 81.0 2DPPC@1|root,332VC@2|Bacteria,1VM0N@1239|Firmicutes,4HNHT@91061|Bacilli,1ZIVE@1386|Bacillus 91061|Bacilli S Phospholipase_D-nuclease N-terminal yxlE - - - - - - - - - - - PLDc_N DYD1_k127_5293849_52 1210908.HSB1_14750 0.000173 47.0 arCOG03953@1|root,arCOG03953@2157|Archaea,2Y1HS@28890|Euryarchaeota,23YXC@183963|Halobacteria 183963|Halobacteria S Domain of unknown function (DUF4177) - - - - - - - - - - - - - DYD1_k127_5293849_6 926569.ANT_00090 1.736e-134 435.0 COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi 2|Bacteria O PFAM band 7 protein hflC - - - - - - - - - - - Band_7 DYD1_k127_5293849_40 926569.ANT_00080 6.091e-38 146.0 COG1725@1|root,COG1725@2|Bacteria,2G7C5@200795|Chloroflexi 200795|Chloroflexi K PFAM regulatory protein GntR HTH - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR DYD1_k127_5293849_4 926569.ANT_01650 6.833e-158 501.0 COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS - 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ DYD1_k127_5293849_23 926569.ANT_01660 1.528e-76 261.0 COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO DYD1_k127_5293849_1 926569.ANT_01680 8.993e-212 683.0 COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi 200795|Chloroflexi S PFAM single-stranded nucleic acid binding R3H domain protein - - - - - - - - - - - - AAA,AAA_30,R3H DYD1_k127_5293849_22 926569.ANT_01690 3.393e-77 264.0 COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi 200795|Chloroflexi F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin DYD1_k127_5293849_17 671143.DAMO_1148 4.686e-91 316.0 COG0123@1|root,COG0123@2|Bacteria,2NP8V@2323|unclassified Bacteria 2|Bacteria BQ Histone deacetylase domain acuC - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl DYD1_k127_5293849_8 28583.AMAG_10443T0 9.323e-130 441.0 COG1233@1|root,KOG4254@2759|Eukaryota,38GIP@33154|Opisthokonta,3NY26@4751|Fungi 4751|Fungi H Phytoene dehydrogenase - - 1.3.99.30 ko:K15745 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R07518,R09692 RC01214,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase DYD1_k127_5293849_53 1380394.JADL01000005_gene5592 0.000224 53.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2TTI0@28211|Alphaproteobacteria,2JRHF@204441|Rhodospirillales 204441|Rhodospirillales I Phytoene synthase - - 2.5.1.103 ko:K21678 - - - - ko00000,ko01000 - - - SQS_PSY DYD1_k127_5293849_7 1047013.AQSP01000134_gene1338 4.516e-131 436.0 COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria 2|Bacteria H Trimethylamine methyltransferase (MTTB) - - 2.1.1.250 ko:K14083 ko00680,ko01120,ko01200,map00680,map01120,map01200 M00563 R09124,R10016 RC00035,RC00732,RC01144,RC02984 ko00000,ko00001,ko00002,ko01000 - - - MTTB DYD1_k127_5293849_29 1089553.Tph_c27670 2.454e-59 212.0 COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales 186801|Clostridia S Methionine synthase B12-binding module cap domain protein - - 2.1.1.13 ko:K00548,ko:K14084 ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230 M00017,M00563 R00946,R09124,R09365 RC00035,RC00113,RC00732,RC01241,RC02984 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2 DYD1_k127_5293849_54 1173029.JH980292_gene2038 0.0008033 50.0 COG0515@1|root,COG0515@2|Bacteria,1G0B6@1117|Cyanobacteria,1H7HZ@1150|Oscillatoriales 1117|Cyanobacteria KLT PFAM Protein kinase domain - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase DYD1_k127_5293849_43 1040987.AZUY01000015_gene517 5.099e-22 110.0 COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria,43N9X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad DYD1_k127_5293849_48 644966.Tmar_1212 1.746e-11 76.0 COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis 186801|Clostridia U TadE-like protein - - - - - - - - - - - - TadE DYD1_k127_5293849_50 357808.RoseRS_3348 1.963e-08 66.0 COG3266@1|root,COG4961@1|root,COG3266@2|Bacteria,COG4961@2|Bacteria,2G7CN@200795|Chloroflexi 200795|Chloroflexi U PFAM TadE family protein - - - - - - - - - - - - TadE DYD1_k127_5293849_41 1121920.AUAU01000006_gene266 1.643e-34 135.0 COG2329@1|root,COG2329@2|Bacteria,3Y5V2@57723|Acidobacteria 57723|Acidobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - - DYD1_k127_5293849_36 324602.Caur_3029 6.433e-45 179.0 COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi,3775M@32061|Chloroflexia 32061|Chloroflexia S Belongs to the UPF0312 family - - - - - - - - - - - - YceI DYD1_k127_5293849_30 926569.ANT_03400 3.334e-53 205.0 COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi 200795|Chloroflexi EGP MFS_1 like family - - - - - - - - - - - - MFS_1 DYD1_k127_5302457_18 926569.ANT_17720 2.291e-35 139.0 COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi 200795|Chloroflexi J PFAM tRNA synthetase class II (G H P and S) hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD1_k127_5302457_19 1121933.AUHH01000036_gene1463 1.261e-33 140.0 COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DP0V@85009|Propionibacteriales 201174|Actinobacteria D Cellulose biosynthesis protein BcsQ soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD1_k127_5302457_9 926569.ANT_19910 1.736e-91 311.0 COG3407@1|root,COG3407@2|Bacteria,2G5SQ@200795|Chloroflexi 200795|Chloroflexi I GHMP kinases N terminal domain mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_N DYD1_k127_5302457_11 926569.ANT_19920 1.621e-75 266.0 COG0750@1|root,COG0750@2|Bacteria,2G6GY@200795|Chloroflexi 200795|Chloroflexi M SMART PDZ DHR GLGF domain protein - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 DYD1_k127_5302457_14 926569.ANT_19930 7.597e-51 193.0 COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi 200795|Chloroflexi C PBS lyase HEAT domain protein repeat-containing protein - - - - - - - - - - - - HEAT_2 DYD1_k127_5302457_16 926550.CLDAP_05630 6.215e-44 171.0 COG0679@1|root,COG0679@2|Bacteria,2G90G@200795|Chloroflexi 200795|Chloroflexi S PFAM Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans DYD1_k127_5302457_23 504728.K649_14130 2.923e-19 90.0 COG1254@1|root,COG1254@2|Bacteria,1WKQ7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Belongs to the acylphosphatase family - - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase DYD1_k127_5302457_20 926569.ANT_31290 3.584e-30 137.0 COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria 2|Bacteria T sh3 domain protein - - 3.2.1.96 ko:K01227,ko:K03642 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH DYD1_k127_5302457_12 326427.Cagg_0777 1.444e-71 249.0 COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi,375AQ@32061|Chloroflexia 32061|Chloroflexia L PFAM DNA repair protein RadC - - - ko:K03630 - - - - ko00000 - - - RadC DYD1_k127_5302457_15 926569.ANT_14000 2.457e-47 177.0 COG1933@1|root,COG1933@2|Bacteria 2|Bacteria L exodeoxyribonuclease I activity - - - - - - - - - - - - Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2 DYD1_k127_5302457_1 926569.ANT_25420 7.963e-206 648.0 COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N DYD1_k127_5302457_5 926569.ANT_14730 1.29e-134 439.0 COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi 200795|Chloroflexi E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 DYD1_k127_5302457_8 926569.ANT_14740 2.605e-107 359.0 COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans DYD1_k127_5302457_22 926569.ANT_20480 2.514e-20 96.0 2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_5302457_24 926569.ANT_20470 1.844e-18 89.0 COG4980@1|root,COG4980@2|Bacteria 2|Bacteria D gas vesicle protein XK27_07760 - - - - - - - - - - - YtxH DYD1_k127_5302457_6 926569.ANT_20460 1.508e-131 441.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi 200795|Chloroflexi H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD1_k127_5302457_3 926569.ANT_14670 7.97e-176 570.0 COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi 200795|Chloroflexi C PFAM aldehyde ferredoxin oxidoreductase - - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N DYD1_k127_5302457_2 765420.OSCT_2101 5.415e-191 610.0 COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi 200795|Chloroflexi E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N DYD1_k127_5302457_21 926569.ANT_14650 1.279e-23 107.0 COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi 200795|Chloroflexi I SCP-2 sterol transfer family - - - - - - - - - - - - SCP2 DYD1_k127_5302457_4 926569.ANT_15960 4.414e-167 546.0 COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi 200795|Chloroflexi F PFAM metal-dependent phosphohydrolase, HD sub domain dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc DYD1_k127_5302457_17 926569.ANT_15970 3.824e-41 164.0 COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi 200795|Chloroflexi K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N DYD1_k127_5302457_13 926569.ANT_15980 4.905e-69 248.0 28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_5302457_0 926569.ANT_15990 1.882e-316 988.0 COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi 200795|Chloroflexi L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom DYD1_k127_5302457_10 926569.ANT_16000 1.266e-88 307.0 COG0836@1|root,COG0836@2|Bacteria,2G5WW@200795|Chloroflexi 200795|Chloroflexi M Nucleotidyl transferase - - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase DYD1_k127_5302457_7 926550.CLDAP_39650 8.564e-114 378.0 COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi 200795|Chloroflexi L TIGRFAM DNA protecting protein DprA - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A DYD1_k127_5305828_7 926569.ANT_18930 1.941e-67 252.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity ftsZ - - ko:K03531,ko:K03832 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko02048,ko03036,ko04812 2.C.1.1 - - DUF3747,DUF4173,FtsK_4TM,HAMP,HATPase_c,HisKA,TonB_C DYD1_k127_5305828_9 926569.ANT_18290 2.857e-57 205.0 COG2077@1|root,COG2077@2|Bacteria,2G8IQ@200795|Chloroflexi 200795|Chloroflexi O Redoxin - - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - - DYD1_k127_5305828_0 926569.ANT_14870 0.0 1301.0 COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT DYD1_k127_5305828_14 1121272.KB903291_gene3317 2.95e-25 111.0 COG2020@1|root,COG2020@2|Bacteria,2IN0C@201174|Actinobacteria,4DE9J@85008|Micromonosporales 201174|Actinobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT DYD1_k127_5305828_12 911045.PSE_1026 1.476e-33 137.0 29YAY@1|root,30K56@2|Bacteria,1P8DZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_5305828_6 324602.Caur_0663 1.5e-67 250.0 COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia 32061|Chloroflexia M PFAM peptidase M1, membrane alanine aminopeptidase - - - - - - - - - - - - Peptidase_M1 DYD1_k127_5305828_16 300852.55771864 1.854e-14 81.0 COG0500@1|root,COG2226@2|Bacteria,1WJ5U@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 DYD1_k127_5305828_4 926569.ANT_13710 9.886e-102 338.0 COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi 200795|Chloroflexi Q PFAM fumarylacetoacetate (FAA) hydrolase - - - - - - - - - - - - DUF2437,FAA_hydrolase DYD1_k127_5305828_3 926569.ANT_11190 3.319e-106 346.0 COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi 200795|Chloroflexi F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase DYD1_k127_5305828_15 926569.ANT_17270 2.916e-15 89.0 COG1547@1|root,COG1547@2|Bacteria 2|Bacteria S Domain of unknown function (DUF309) ypuF - - ko:K09763 - - - - ko00000 - - - DUF309 DYD1_k127_5305828_13 1254432.SCE1572_08445 7.273e-30 133.0 COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,42Y4G@68525|delta/epsilon subdivisions,2WTC4@28221|Deltaproteobacteria,2YV68@29|Myxococcales 28221|Deltaproteobacteria C Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM DYD1_k127_5305828_1 1242864.D187_002935 2.735e-109 366.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42NP2@68525|delta/epsilon subdivisions,2WIY2@28221|Deltaproteobacteria,2YUJC@29|Myxococcales 28221|Deltaproteobacteria C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH DYD1_k127_5305828_19 324602.Caur_1283 0.0009956 51.0 COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_5305828_8 1068978.AMETH_5267 5.563e-60 213.0 COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria,4E380@85010|Pseudonocardiales 201174|Actinobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD1_k127_5305828_11 591158.SSMG_01277 4.68e-49 177.0 COG0640@1|root,COG0640@2|Bacteria,2IHS2@201174|Actinobacteria 201174|Actinobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 DYD1_k127_5305828_5 1382356.JQMP01000003_gene1359 1.227e-70 258.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia 189775|Thermomicrobia T Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase DYD1_k127_5305828_10 1396141.BATP01000038_gene1221 3.515e-55 208.0 COG1524@1|root,COG1524@2|Bacteria,46TNY@74201|Verrucomicrobia,2IV18@203494|Verrucomicrobiae 2|Bacteria U Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - CHB_HEX_C_1,PA14,Phosphodiest DYD1_k127_5305828_18 316056.RPC_4871 9.362e-08 55.0 COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,3JV5F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Pyridoxal-dependent decarboxylase conserved domain MA20_08345 - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC DYD1_k127_5305828_2 1128421.JAGA01000002_gene1952 1.053e-107 362.0 COG0834@1|root,COG0834@2|Bacteria 2|Bacteria ET amino acid transport - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K09969 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 DYD1_k127_5307805_2 246194.CHY_2547 8.696e-210 663.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,42F4E@68295|Thermoanaerobacterales 186801|Clostridia C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N DYD1_k127_5307805_6 926569.ANT_16300 2.154e-93 316.0 COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi 200795|Chloroflexi E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer DYD1_k127_5307805_10 316274.Haur_2516 1.1e-47 184.0 COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi,3774D@32061|Chloroflexia 32061|Chloroflexia L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N DYD1_k127_5307805_9 926569.ANT_13740 1.848e-52 192.0 COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi 200795|Chloroflexi L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC DYD1_k127_5307805_5 926569.ANT_13730 1.039e-95 319.0 COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg DYD1_k127_5307805_7 1128421.JAGA01000002_gene1072 2.213e-83 285.0 COG1801@1|root,COG1801@2|Bacteria,2NPDU@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 DYD1_k127_5307805_4 429009.Adeg_1192 1.679e-117 387.0 COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,24GKF@186801|Clostridia,42HT2@68295|Thermoanaerobacterales 186801|Clostridia C TIGRFAM zinc-binding alcohol dehydrogenase family protein - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_5307805_3 479434.Sthe_1716 4.594e-189 597.0 COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,27Y0U@189775|Thermomicrobia 189775|Thermomicrobia I Myo-inositol-1-phosphate synthase - - 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth DYD1_k127_5307805_8 316274.Haur_1267 2.084e-53 204.0 COG2204@1|root,COG5002@1|root,COG2204@2|Bacteria,COG5002@2|Bacteria,2GAA9@200795|Chloroflexi,376WV@32061|Chloroflexia 32061|Chloroflexia T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Response_reg DYD1_k127_5307805_0 926550.CLDAP_29100 5.409e-301 931.0 COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi 200795|Chloroflexi E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N DYD1_k127_5307805_1 926569.ANT_25010 1.442e-249 774.0 COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi 200795|Chloroflexi H Lysine-2,3-aminomutase - - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Acetyltransf_1,LAM_C,Radical_SAM DYD1_k127_5310896_0 326427.Cagg_0335 2.786e-118 385.0 COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,376F8@32061|Chloroflexia 32061|Chloroflexia E PFAM ABC transporter related - - - ko:K09972 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran DYD1_k127_5310896_2 489825.LYNGBM3L_35570 1.429e-82 296.0 COG0765@1|root,COG0765@2|Bacteria,1G2E3@1117|Cyanobacteria,1H9HA@1150|Oscillatoriales 1117|Cyanobacteria P TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family - - - ko:K09971 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 DYD1_k127_5310896_1 1173026.Glo7428_1854 1.128e-95 327.0 COG4597@1|root,COG4597@2|Bacteria,1FZWE@1117|Cyanobacteria 1117|Cyanobacteria P TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family bgtB - - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 DYD1_k127_5313469_18 67257.JODR01000001_gene951 4.207e-35 146.0 COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria 201174|Actinobacteria L formamidopyrimidine-DNA glycosylase - - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD1_k127_5313469_17 1128421.JAGA01000001_gene2345 1.052e-36 162.0 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - Amidase_2,CARDB,CBM_3,DUF4091,HYR,Kelch_1,MAM,PA14,PKD,Peptidase_M43,Reprolysin_3 DYD1_k127_5313469_10 1343739.PAP_08680 2.124e-43 171.0 arCOG11292@1|root,arCOG11292@2157|Archaea,2Y3FT@28890|Euryarchaeota,2443S@183968|Thermococci 183968|Thermococci - - - - - - - - - - - - - - - DYD1_k127_5313469_7 1541065.JRFE01000014_gene1350 2.952e-76 274.0 28M84@1|root,2ZAMA@2|Bacteria,1G3CX@1117|Cyanobacteria,3VJH1@52604|Pleurocapsales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5313469_19 28072.Nos7524_1449 7.283e-35 140.0 COG1943@1|root,COG1943@2|Bacteria,1G6DG@1117|Cyanobacteria,1HJV9@1161|Nostocales 1117|Cyanobacteria L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp DYD1_k127_5313469_12 1278073.MYSTI_06570 4.367e-41 165.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddlB1 - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD1_k127_5313469_27 1530186.JQEY01000001_gene763 2.664e-09 70.0 2C1UQ@1|root,33VUD@2|Bacteria,1RM45@1224|Proteobacteria,2UBKR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_5313469_0 926550.CLDAP_13490 4.025e-253 806.0 COG1205@1|root,COG1403@1|root,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi 200795|Chloroflexi L DEAD DEAH box helicase domain protein - - - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,HNH,Helicase_C DYD1_k127_5313469_2 234267.Acid_5780 1.854e-123 437.0 COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria 2|Bacteria T PFAM Protein kinase domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C DYD1_k127_5313469_22 1267533.KB906733_gene2843 3.581e-23 109.0 COG2844@1|root,COG2844@2|Bacteria 2|Bacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 DYD1_k127_5313469_25 1120936.KB907227_gene2935 5.635e-11 65.0 COG1522@1|root,COG1522@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - AsnC_trans_reg DYD1_k127_5313469_6 926569.ANT_29930 9.579e-98 327.0 COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi 200795|Chloroflexi P Formate/nitrite transporter - - - ko:K06212 - - - - ko00000,ko02000 1.A.16.1.1,1.A.16.1.3 - - Form_Nir_trans DYD1_k127_5313469_14 1380390.JIAT01000010_gene4036 5.422e-38 155.0 COG0697@1|root,COG0697@2|Bacteria,2ID9Z@201174|Actinobacteria,4CSCH@84995|Rubrobacteria 84995|Rubrobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_5313469_23 1379270.AUXF01000001_gene2369 1.552e-18 93.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 DYD1_k127_5313469_21 868131.MSWAN_1517 1.472e-25 124.0 arCOG00567@1|root,arCOG00567@2157|Archaea 2157|Archaea S glycosyl transferase family - - 2.4.99.18 ko:K07151 ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141 M00072 R04216,R05976 RC00005,RC00482 ko00000,ko00001,ko00002,ko01000,ko01003 - GT66 - PMT_2 DYD1_k127_5313469_3 987059.RBXJA2T_13469 1.675e-122 406.0 COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,2VPGH@28216|Betaproteobacteria 28216|Betaproteobacteria M Pfam Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_5313469_1 926569.ANT_25960 7.086e-155 511.0 COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM DYD1_k127_5313469_15 926569.ANT_07030 6.047e-38 146.0 COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi 200795|Chloroflexi S PFAM thioesterase superfamily protein - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 DYD1_k127_5313469_4 326427.Cagg_3109 3.995e-122 400.0 COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia 32061|Chloroflexia C PFAM luciferase family protein - - - - - - - - - - - - Bac_luciferase DYD1_k127_5313469_26 251221.35211983 8.591e-10 70.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_5313469_16 485913.Krac_5098 4.815e-37 147.0 COG1695@1|root,COG1695@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - PadR DYD1_k127_5313469_24 309801.trd_0152 1.956e-18 87.0 2EQM1@1|root,33I6Z@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 DYD1_k127_5313469_9 324602.Caur_1278 6.048e-58 210.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding ntcA - - ko:K01420,ko:K10716,ko:K10914,ko:K16922 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko01002,ko02000,ko03000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - HTH_Crp_2,cNMP_binding DYD1_k127_5313469_5 1356854.N007_03670 1.099e-101 341.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,279CW@186823|Alicyclobacillaceae 91061|Bacilli C Ferredoxin--NADP reductase trxB5 - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - - Pyr_redox_2 DYD1_k127_5313469_11 926569.ANT_30170 7.041e-42 171.0 COG0705@1|root,COG0705@2|Bacteria,2G7BZ@200795|Chloroflexi 200795|Chloroflexi S PFAM Rhomboid family protein - - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid DYD1_k127_5313469_8 926569.ANT_30180 2.238e-66 233.0 COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi 200795|Chloroflexi F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin DYD1_k127_5313469_28 926569.ANT_30190 0.0004293 44.0 COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi 200795|Chloroflexi S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 DYD1_k127_5319845_32 357808.RoseRS_0820 1.306e-05 56.0 COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi,3753X@32061|Chloroflexia 32061|Chloroflexia D PFAM cell divisionFtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma DYD1_k127_5319845_19 1166018.FAES_pFAES01115 8.765e-45 169.0 COG3544@1|root,COG3544@2|Bacteria,4NM7E@976|Bacteroidetes,47QEE@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 DYD1_k127_5319845_13 926569.ANT_30100 3.053e-64 242.0 COG2905@1|root,COG2905@2|Bacteria 2|Bacteria T signal-transduction protein containing cAMP-binding and CBS domains - - - - - - - - - - - - Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding DYD1_k127_5319845_15 926569.ANT_31550 1.218e-55 201.0 COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi 200795|Chloroflexi J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD1_k127_5319845_23 525904.Tter_1090 9.036e-31 125.0 COG1950@1|root,COG1950@2|Bacteria,2NQ43@2323|unclassified Bacteria 2|Bacteria S Mycobacterial 4 TMS phage holin, superfamily IV yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 DYD1_k127_5319845_14 926550.CLDAP_01500 4.748e-61 228.0 COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi 200795|Chloroflexi S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD1_k127_5319845_4 926569.ANT_31560 1.086e-113 379.0 COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi 200795|Chloroflexi L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N DYD1_k127_5319845_9 926569.ANT_30070 1.299e-71 260.0 COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi 200795|Chloroflexi J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB DYD1_k127_5319845_21 926569.ANT_03110 1.999e-39 158.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B DYD1_k127_5319845_6 926569.ANT_06880 3.264e-105 372.0 COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria 2|Bacteria T PhoQ Sensor devS GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K07682 ko02020,map02020 M00482 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3 DYD1_k127_5319845_2 1128421.JAGA01000003_gene2811 1.34e-115 385.0 COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria 2|Bacteria E Threonine synthase MA20_41710 - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_5319845_1 880073.Calab_3587 1.273e-162 530.0 COG1086@1|root,COG1086@2|Bacteria 2|Bacteria GM Polysaccharide biosynthesis protein - - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Bac_transf,CoA_binding_3,Glycos_transf_4,HTH_45,LicD DYD1_k127_5319845_26 926569.ANT_06730 7.571e-25 109.0 2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_5319845_28 926550.CLDAP_31420 2.207e-15 90.0 COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi 200795|Chloroflexi K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_5319845_25 926550.CLDAP_09780 4.881e-25 118.0 COG3595@1|root,COG3595@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4097 DYD1_k127_5319845_22 926569.ANT_06720 1.593e-31 128.0 COG3877@1|root,COG3877@2|Bacteria,2G734@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF2089) - - - - - - - - - - - - DUF2089 DYD1_k127_5319845_3 926550.CLDAP_34690 2.033e-115 382.0 COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi 200795|Chloroflexi E PFAM aminotransferase class V - - - - - - - - - - - - Aminotran_5 DYD1_k127_5319845_30 316274.Haur_3630 5.902e-11 75.0 COG1807@1|root,COG1807@2|Bacteria,2G9FD@200795|Chloroflexi,374XJ@32061|Chloroflexia 32061|Chloroflexia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2,TPR_16,TPR_8 DYD1_k127_5319845_10 357808.RoseRS_3316 3.892e-70 255.0 COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,375ER@32061|Chloroflexia 32061|Chloroflexia G PFAM inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P DYD1_k127_5319845_8 926569.ANT_30490 1.151e-78 272.0 COG0496@1|root,COG0496@2|Bacteria 2|Bacteria P Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD1_k127_5319845_11 926569.ANT_24870 7.624e-70 246.0 COG1418@1|root,COG1418@2|Bacteria,2G77Y@200795|Chloroflexi 200795|Chloroflexi S PFAM metal-dependent phosphohydrolase, HD sub domain - - - ko:K06950 - - - - ko00000 - - - HD DYD1_k127_5319845_16 1487953.JMKF01000006_gene5651 8.597e-50 181.0 COG3238@1|root,COG3238@2|Bacteria 2|Bacteria S Putative inner membrane exporter, YdcZ - - - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ DYD1_k127_5319845_7 861299.J421_1634 1.458e-93 320.0 COG3214@1|root,COG3214@2|Bacteria 2|Bacteria J Protein conserved in bacteria - - - - - - - - - - - - HTH_42 DYD1_k127_5319845_20 110319.CF8_4080 8.072e-42 163.0 COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4DNET@85009|Propionibacteriales 201174|Actinobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux DYD1_k127_5319845_5 316274.Haur_0231 1.684e-109 373.0 COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,377ZZ@32061|Chloroflexia 32061|Chloroflexia P PFAM ABC transporter related - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran DYD1_k127_5319845_24 326427.Cagg_2175 1.801e-25 118.0 COG0619@1|root,COG0619@2|Bacteria,2G71W@200795|Chloroflexi,3779W@32061|Chloroflexia 32061|Chloroflexia P PFAM cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ DYD1_k127_5319845_18 316274.Haur_3809 8.289e-45 181.0 COG1657@1|root,COG1657@2|Bacteria,2G8NR@200795|Chloroflexi,37742@32061|Chloroflexia 32061|Chloroflexia I Prenyltransferase and squalene oxidase repeat - - - - - - - - - - - - Prenyltrans DYD1_k127_5319845_12 661478.OP10G_0619 2.786e-66 245.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase DYD1_k127_5319845_29 378806.STAUR_5747 8.575e-13 81.0 COG1287@1|root,COG1287@2|Bacteria,1PCK3@1224|Proteobacteria,432KV@68525|delta/epsilon subdivisions,2WXVJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_5319845_0 926569.ANT_19070 1.545e-229 724.0 COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi 200795|Chloroflexi S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnj - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL DYD1_k127_5319845_17 926569.ANT_26490 8.096e-47 188.0 COG0760@1|root,COG0760@2|Bacteria,2G9A4@200795|Chloroflexi 200795|Chloroflexi M PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3,SurA_N_3 DYD1_k127_5328904_5 1278073.MYSTI_04478 4.218e-84 291.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MCR@68525|delta/epsilon subdivisions,2WJXI@28221|Deltaproteobacteria 28221|Deltaproteobacteria EK PFAM aminotransferase class I and II lysN - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2 DYD1_k127_5328904_1 1121382.JQKG01000026_gene2918 2.003e-177 563.0 COG3185@1|root,COG3185@2|Bacteria 2|Bacteria E 4-Hydroxyphenylpyruvate dioxygenase hpd GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 ko:K00457,ko:K16421 ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130 M00044 R01372,R02521,R06632 RC00505,RC00738,RC01471 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 DYD1_k127_5328904_4 765420.OSCT_2639 3.877e-88 310.0 COG0179@1|root,COG0179@2|Bacteria,2G7MW@200795|Chloroflexi,375D5@32061|Chloroflexia 32061|Chloroflexia Q PFAM fumarylacetoacetate (FAA) hydrolase - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase DYD1_k127_5328904_0 867845.KI911784_gene2224 1.299e-203 639.0 COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi,3766I@32061|Chloroflexia 32061|Chloroflexia Q PFAM homogentisate 12-dioxygenase - - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA DYD1_k127_5328904_8 1157490.EL26_09010 2.463e-62 222.0 COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279PY@186823|Alicyclobacillaceae 91061|Bacilli S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct DYD1_k127_5328904_6 926569.ANT_15610 8.693e-73 256.0 COG1912@1|root,COG1912@2|Bacteria,2G6NI@200795|Chloroflexi 200795|Chloroflexi S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans DYD1_k127_5328904_2 926569.ANT_15620 1.247e-175 567.0 COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi 200795|Chloroflexi P PFAM ABC transporter related - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran DYD1_k127_5328904_10 926569.ANT_15630 1.118e-48 180.0 COG4720@1|root,COG4720@2|Bacteria,2G91D@200795|Chloroflexi 200795|Chloroflexi S ECF-type riboflavin transporter, S component - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS DYD1_k127_5328904_9 926569.ANT_15640 1.853e-61 222.0 COG0619@1|root,COG0619@2|Bacteria,2G8RH@200795|Chloroflexi 200795|Chloroflexi P Cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ DYD1_k127_5328904_11 926569.ANT_19610 1.345e-43 168.0 COG0546@1|root,COG0546@2|Bacteria 2|Bacteria S glycolate biosynthetic process - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 DYD1_k127_5328904_7 525904.Tter_1099 3.912e-65 240.0 COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - - DYD1_k127_5328904_3 485913.Krac_4421 8.554e-99 334.0 COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi 200795|Chloroflexi EGP PFAM major facilitator superfamily MFS_1 - - - ko:K08162 - - - - ko00000,ko02000 2.A.1.2.21 - - MFS_1,MFS_1_like,Sugar_tr DYD1_k127_5333591_0 452637.Oter_2460 2.297e-94 323.0 COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae 74201|Verrucomicrobia C PFAM NADH Ubiquinone plastoquinone (complex I) - - - - - - - - - - - - Proton_antipo_M DYD1_k127_5333591_2 330214.NIDE0991 1.529e-05 52.0 COG1579@1|root,COG1579@2|Bacteria,3J0UV@40117|Nitrospirae 40117|Nitrospirae S C4-type zinc ribbon domain - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 DYD1_k127_5333591_1 1307761.L21SP2_0922 7.653e-06 50.0 COG2204@1|root,COG2204@2|Bacteria,2J5NY@203691|Spirochaetes 203691|Spirochaetes T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains rrp-2 - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5340130_2 926569.ANT_18900 3e-53 198.0 COG0340@1|root,COG0340@2|Bacteria,2G6WF@200795|Chloroflexi 200795|Chloroflexi H biotin lipoate A B protein ligase birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB DYD1_k127_5340130_3 469381.Dpep_0962 3.356e-50 184.0 COG0537@1|root,COG0537@2|Bacteria,3TB29@508458|Synergistetes 508458|Synergistetes FG PFAM histidine triad (HIT) protein - - 2.7.7.53 ko:K19710 ko00230,map00230 - R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 - - - HIT DYD1_k127_5340130_0 485913.Krac_12015 1.16e-138 452.0 COG0183@1|root,COG0183@2|Bacteria,2G66E@200795|Chloroflexi 200795|Chloroflexi I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD1_k127_5340130_1 998674.ATTE01000001_gene3216 3.664e-102 342.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RY2T@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Dehydrogenase paaH - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N DYD1_k127_5340130_4 76114.ebA2650 5.306e-07 62.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,2KUUQ@206389|Rhodocyclales 206389|Rhodocyclales U Involved in the tonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N DYD1_k127_5344342_0 1191523.MROS_2798 1.471e-229 722.0 COG0574@1|root,COG0574@2|Bacteria 2|Bacteria G Belongs to the PEP-utilizing enzyme family - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_2,PPDK_N,Response_reg DYD1_k127_534822_9 1051632.TPY_1656 1.376e-11 66.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WCEQ@538999|Clostridiales incertae sedis 186801|Clostridia L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD1_k127_534822_5 765420.OSCT_1050 3.985e-33 136.0 COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,375N3@32061|Chloroflexia 32061|Chloroflexia S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX DYD1_k127_534822_0 926569.ANT_16100 2.062e-215 679.0 COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi 200795|Chloroflexi S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 DYD1_k127_534822_7 1123367.C666_18830 4.324e-23 106.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2VHHB@28216|Betaproteobacteria,2KVAP@206389|Rhodocyclales 206389|Rhodocyclales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K07665 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_534822_6 326427.Cagg_3335 7.681e-28 124.0 COG0500@1|root,COG2226@2|Bacteria,2GBRI@200795|Chloroflexi,3769K@32061|Chloroflexia 32061|Chloroflexia H PFAM Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_25 DYD1_k127_534822_8 479433.Caci_6625 8.887e-23 104.0 2ES3U@1|root,33JNT@2|Bacteria,2GPSP@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_534822_3 926569.ANT_14280 5.93e-126 415.0 COG0508@1|root,COG0508@2|Bacteria,2G619@200795|Chloroflexi 200795|Chloroflexi C Catalytic domain of components of various dehydrogenase complexes - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_534822_1 926569.ANT_14270 1.251e-169 539.0 COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi 200795|Chloroflexi C PFAM Transketolase central region - - 1.2.4.1,1.2.4.4 ko:K00162,ko:K11381,ko:K21417 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_534822_2 926569.ANT_14260 6.444e-142 458.0 COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi 200795|Chloroflexi C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD1_k127_534822_4 797299.HALLA_03760 9.48e-56 211.0 COG0697@1|root,arCOG00271@2157|Archaea,2XY2J@28890|Euryarchaeota,23Z1Z@183963|Halobacteria 183963|Halobacteria G EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_5350359_12 926569.ANT_27070 5.323e-35 137.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi 200795|Chloroflexi V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_5350359_2 926569.ANT_27060 1.629e-103 352.0 COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi 200795|Chloroflexi P Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5350359_9 1089548.KI783301_gene806 1.399e-63 223.0 COG1695@1|root,COG1695@2|Bacteria,1V6TJ@1239|Firmicutes,4HN21@91061|Bacilli,3WG5C@539002|Bacillales incertae sedis 91061|Bacilli K Transcriptional regulator PadR-like family padR - - - - - - - - - - - PadR,Vir_act_alpha_C DYD1_k127_5350359_1 555779.Dthio_PD1478 1.363e-109 365.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria,2MAU1@213115|Desulfovibrionales 28221|Deltaproteobacteria L PFAM transposase IS116 IS110 IS902 family protein - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 DYD1_k127_5350359_4 1128421.JAGA01000003_gene3545 7.636e-91 307.0 COG1131@1|root,COG1131@2|Bacteria,2NQB3@2323|unclassified Bacteria 2|Bacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5350359_5 383372.Rcas_2356 2.329e-88 299.0 COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi,3768D@32061|Chloroflexia 32061|Chloroflexia V PFAM ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD1_k127_5350359_8 316274.Haur_1012 1.886e-65 238.0 COG0454@1|root,COG1246@1|root,COG0456@2|Bacteria,COG1246@2|Bacteria,2G8UQ@200795|Chloroflexi 200795|Chloroflexi K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_5350359_15 1463854.JOHT01000012_gene4424 1.216e-27 120.0 COG1011@1|root,COG1011@2|Bacteria,2I92U@201174|Actinobacteria 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - - ko:K07025 - - - - ko00000 - - - Hydrolase DYD1_k127_5350359_14 926569.ANT_28120 6.143e-31 139.0 COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi 200795|Chloroflexi M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,LysM DYD1_k127_5350359_16 935863.AWZR01000003_gene2674 4.096e-18 89.0 2EGCD@1|root,33A46@2|Bacteria,1NMIX@1224|Proteobacteria,1SIUN@1236|Gammaproteobacteria,1X8EM@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4190) - - - - - - - - - - - - DUF4190 DYD1_k127_5350359_13 926569.ANT_28130 3.015e-34 138.0 COG2905@1|root,COG2905@2|Bacteria,2G9RX@200795|Chloroflexi 200795|Chloroflexi T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD1_k127_5350359_6 926569.ANT_25680 5.946e-86 293.0 COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi 200795|Chloroflexi I PFAM diacylglycerol kinase catalytic region - - - - - - - - - - - - DAGK_cat DYD1_k127_5350359_7 926569.ANT_25670 1.288e-69 262.0 2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi 200795|Chloroflexi S Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C_3 DYD1_k127_5350359_3 383372.Rcas_0998 5.422e-95 332.0 COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia 32061|Chloroflexia F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK - 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg DYD1_k127_5350359_17 1249997.JHZW01000002_gene1687 2.355e-14 78.0 COG2197@1|root,COG2197@2|Bacteria,4PKH3@976|Bacteroidetes,1IK7Z@117743|Flavobacteriia 976|Bacteroidetes T PFAM Response regulator receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_5350359_0 926569.ANT_05230 4.987e-256 804.0 COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi 200795|Chloroflexi L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N DYD1_k127_5350359_10 926569.ANT_05550 3.817e-50 195.0 COG2182@1|root,COG2182@2|Bacteria 2|Bacteria G maltose binding - - - ko:K02027,ko:K15770 ko02010,map02010 M00207,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 - - SBP_bac_1,SBP_bac_8 DYD1_k127_5350359_11 765420.OSCT_1801 7.391e-48 184.0 COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia 32061|Chloroflexia C PFAM MOFRL domain protein - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL DYD1_k127_535158_9 1051632.TPY_1656 2.801e-11 65.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WCEQ@538999|Clostridiales incertae sedis 186801|Clostridia L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD1_k127_535158_8 246197.MXAN_5307 5.221e-22 102.0 COG4430@1|root,COG4430@2|Bacteria,1NASK@1224|Proteobacteria,43202@68525|delta/epsilon subdivisions,2WX2P@28221|Deltaproteobacteria,2Z2U2@29|Myxococcales 28221|Deltaproteobacteria S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA DYD1_k127_535158_5 1173028.ANKO01000037_gene3747 1.15e-59 222.0 COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,1H8N9@1150|Oscillatoriales 1117|Cyanobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short DYD1_k127_535158_0 926569.ANT_16170 1.485e-218 685.0 COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi 200795|Chloroflexi H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD DYD1_k127_535158_6 926550.CLDAP_17740 5.594e-45 177.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase paiA - 2.3.1.128,2.3.1.183,2.7.6.3 ko:K00950,ko:K03789,ko:K03823 ko00440,ko00790,ko01100,ko01130,map00440,map00790,map01100,map01130 M00126,M00841 R03503,R08871,R08938 RC00002,RC00004,RC00017,RC00064 ko00000,ko00001,ko00002,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_535158_3 926569.ANT_16180 3.035e-122 405.0 COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi 200795|Chloroflexi G PFAM PfkB domain protein adoK - 2.7.1.20 ko:K00856 ko00230,ko01100,map00230,map01100 - R00185 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB DYD1_k127_535158_4 926569.ANT_16190 1.16e-107 360.0 COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B DYD1_k127_535158_1 926569.ANT_14290 2.96e-151 507.0 COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi 200795|Chloroflexi M Lytic transglycosylase catalytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,TPR_16,TPR_6 DYD1_k127_535158_2 926569.ANT_09980 2.377e-144 464.0 COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi 200795|Chloroflexi K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 DYD1_k127_5366867_7 1089550.ATTH01000001_gene967 5.347e-37 144.0 COG2379@1|root,COG2379@2|Bacteria,4NI08@976|Bacteroidetes,1FJ0H@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C MOFRL family - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL DYD1_k127_5366867_13 1541065.JRFE01000032_gene3566 8.874e-05 46.0 COG0783@1|root,COG0783@2|Bacteria,1G54E@1117|Cyanobacteria,3VJJ7@52604|Pleurocapsales 2|Bacteria P DNA-binding ferritin-like protein (Oxidative damage protectant) dps GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0006950,GO:0008150,GO:0008199,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin DYD1_k127_5366867_0 926569.ANT_31260 6.112e-213 672.0 COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi 200795|Chloroflexi G Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - - - - - - - - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_5366867_5 926550.CLDAP_16480 6.526e-59 222.0 COG0745@1|root,COG1672@1|root,COG0745@2|Bacteria,COG1672@2|Bacteria,2G778@200795|Chloroflexi 200795|Chloroflexi K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Trans_reg_C DYD1_k127_5366867_3 926569.ANT_00400 5.408e-68 244.0 28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_5366867_2 926569.ANT_00390 4.348e-130 437.0 COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi 200795|Chloroflexi G Carbohydrate kinase - - - - - - - - - - - - MutL DYD1_k127_5366867_9 926569.ANT_00380 4.452e-29 127.0 2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_5366867_4 926569.ANT_00370 2.374e-62 238.0 COG1187@1|root,COG1187@2|Bacteria 2|Bacteria J pseudouridine synthase activity rluB - 5.4.99.19,5.4.99.20,5.4.99.22 ko:K06178,ko:K06181,ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_5366867_10 926569.ANT_00360 8.187e-26 116.0 2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_5366867_8 926569.ANT_00350 1.082e-36 149.0 28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_5366867_6 357808.RoseRS_1491 4.431e-47 185.0 COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi,374ZP@32061|Chloroflexia 32061|Chloroflexia S NurA - - - - - - - - - - - - NurA DYD1_k127_5366867_11 317619.ANKN01000013_gene3526 1.786e-15 86.0 2C7F0@1|root,2Z832@2|Bacteria,1FZVC@1117|Cyanobacteria 1117|Cyanobacteria S PFAM HAS barrel domain - - - - - - - - - - - - HAS-barrel DYD1_k127_5366867_1 357808.RoseRS_1701 1.797e-154 511.0 COG0433@1|root,COG0433@2|Bacteria,2G62A@200795|Chloroflexi,3751Q@32061|Chloroflexia 32061|Chloroflexia S Domain of unknown function DUF87 - - - ko:K06915 - - - - ko00000 - - - DUF87,HAS-barrel DYD1_k127_5394288_0 926569.ANT_20730 0.0 1110.0 COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi 200795|Chloroflexi L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V DYD1_k127_5394288_2 926569.ANT_13270 4.886e-87 297.0 COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi 200795|Chloroflexi GK PFAM ROK family protein - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK DYD1_k127_5394288_3 1206720.BAFQ01000135_gene3381 5.507e-69 254.0 COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4FZFP@85025|Nocardiaceae 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_5394288_4 1116232.AHBF01000175_gene7131 3.415e-43 179.0 COG0601@1|root,COG0601@2|Bacteria,2GMR8@201174|Actinobacteria 201174|Actinobacteria EP ABC-type dipeptide oligopeptide nickel transport - - - - - - - - - - - - BPD_transp_1 DYD1_k127_5394288_5 1123279.ATUS01000004_gene3038 5.51e-40 160.0 COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,1RNBC@1236|Gammaproteobacteria,1JBZM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EP Binding-protein-dependent transport system inner membrane component gsiD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02034,ko:K13891 ko02010,ko02024,map02010,map02024 M00239,M00348 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.11 - iECABU_c1320.ECABU_c08730,iECP_1309.ECP_0846,ic_1306.c0917 BPD_transp_1,OppC_N DYD1_k127_5394288_1 643648.Slip_0683 3.842e-92 312.0 COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia,42KBW@68298|Syntrophomonadaceae 186801|Clostridia P Phosphate transporter family pit - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 DYD1_k127_5419516_0 1382306.JNIM01000001_gene903 4.022e-128 420.0 COG3191@1|root,COG3191@2|Bacteria,2G83Q@200795|Chloroflexi 200795|Chloroflexi EQ Peptidase family S58 - - - - - - - - - - - - Peptidase_S58 DYD1_k127_5419516_3 926569.ANT_22770 3.585e-55 202.0 COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi 200795|Chloroflexi S PFAM membrane-flanked domain - - - - - - - - - - - - SHOCT,bPH_2 DYD1_k127_5419516_2 926569.ANT_04260 1.982e-59 211.0 COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi 200795|Chloroflexi O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD1_k127_5419516_1 926569.ANT_27830 1.208e-95 329.0 COG1994@1|root,COG1994@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - Peptidase_M50 DYD1_k127_5419516_4 1195236.CTER_0903 1.056e-43 169.0 COG1020@1|root,COG1020@2|Bacteria,1TW32@1239|Firmicutes,24CC9@186801|Clostridia,3WNZ7@541000|Ruminococcaceae 186801|Clostridia Q Condensation domain - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,adh_short DYD1_k127_5419516_5 926569.ANT_01590 1.889e-24 116.0 COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi 200795|Chloroflexi M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - Pro_isomerase,Thioredoxin_4 DYD1_k127_543068_4 926550.CLDAP_34280 1.41e-99 328.0 COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi 200795|Chloroflexi C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128,ko:K22187 ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_543068_8 1121468.AUBR01000038_gene1964 1.358e-32 135.0 COG1280@1|root,COG1280@2|Bacteria,1V725@1239|Firmicutes,24KQ7@186801|Clostridia,42GHE@68295|Thermoanaerobacterales 186801|Clostridia E LysE type translocator - - - - - - - - - - - - LysE DYD1_k127_543068_0 1121405.dsmv_1320 0.0 1303.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales 28221|Deltaproteobacteria G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N DYD1_k127_543068_7 926569.ANT_17920 2.146e-33 132.0 COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi 200795|Chloroflexi P PFAM Rieske 2Fe-2S domain protein - - 1.7.1.15 ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske DYD1_k127_543068_6 926569.ANT_17930 9.009e-52 186.0 COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi 200795|Chloroflexi C SUF system FeS assembly protein, NifU family - - - ko:K04488 - - - - ko00000 - - - NifU_N DYD1_k127_543068_2 926569.ANT_17940 4.034e-174 561.0 COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi 200795|Chloroflexi E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 DYD1_k127_543068_3 926569.ANT_17960 2.039e-155 507.0 COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi 200795|Chloroflexi O TIGRFAM FeS assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 DYD1_k127_543068_1 926569.ANT_17970 1.414e-251 781.0 COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi 200795|Chloroflexi O TIGRFAM FeS assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 DYD1_k127_543068_5 926569.ANT_17980 7.086e-56 197.0 COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi 200795|Chloroflexi O PFAM ABC transporter related sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran DYD1_k127_5433437_3 1209984.BN978_02620 4.878e-30 138.0 COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,2370G@1762|Mycobacteriaceae 201174|Actinobacteria S amidohydrolase - - - - - - - - - - - - Amidohydro_3 DYD1_k127_5433437_7 1464048.JNZS01000005_gene5589 2.862e-12 76.0 COG2133@1|root,COG3291@1|root,COG3507@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4D8ZK@85008|Micromonosporales 201174|Actinobacteria G Protein of unknown function (DUF1349) - - - - - - - - - - - - CBM_6,DUF1349,GSDH,PKD,ThuA DYD1_k127_5433437_5 267608.RSp0085 5.541e-22 113.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VM13@28216|Betaproteobacteria 28216|Betaproteobacteria M rhs-related protein - - - - - - - - - - - - RHS,RHS_repeat DYD1_k127_5433437_1 479434.Sthe_1513 9.028e-31 141.0 COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,27YYI@189775|Thermomicrobia 189775|Thermomicrobia S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD1_k127_5433437_6 563192.HMPREF0179_00003 6.599e-14 86.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42PEY@68525|delta/epsilon subdivisions,2WJJ3@28221|Deltaproteobacteria,2MAY5@213115|Desulfovibrionales 28221|Deltaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD1_k127_5433437_4 215803.DB30_3897 4.66e-23 116.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42PEY@68525|delta/epsilon subdivisions,2WJJ3@28221|Deltaproteobacteria,2YUIV@29|Myxococcales 28221|Deltaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 DYD1_k127_5433437_2 649638.Trad_2500 1.956e-30 140.0 COG3409@1|root,COG3409@2|Bacteria,1WMAM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 DYD1_k127_5433437_0 926569.ANT_22190 3.23e-34 147.0 COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi 2|Bacteria S Ig-like domain from next to BRCA1 gene - - - - - - - - - - - - DUF11,N_BRCA1_IG DYD1_k127_5434517_3 326427.Cagg_0069 4.122e-44 166.0 COG0247@1|root,COG0247@2|Bacteria,2G7VD@200795|Chloroflexi,3754W@32061|Chloroflexia 32061|Chloroflexia C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - 1.1.5.3 ko:K00113 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - CCG,Fer4_8 DYD1_k127_5434517_1 926569.ANT_13960 2.133e-169 548.0 COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi 200795|Chloroflexi S PFAM Amidohydrolase 3 - - - - - - - - - - - - Amidohydro_3 DYD1_k127_5434517_0 926569.ANT_25100 1.023e-172 562.0 COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi 200795|Chloroflexi J Selenocysteine-specific translation elongation factor selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 DYD1_k127_5434517_2 926569.ANT_25090 1.499e-56 221.0 COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi 200795|Chloroflexi D peptidase - - - - - - - - - - - - - DYD1_k127_5434517_4 383372.Rcas_2737 8.651e-06 57.0 COG0651@1|root,COG0651@2|Bacteria,2GAD0@200795|Chloroflexi,375GT@32061|Chloroflexia 32061|Chloroflexia CP PFAM NADH Ubiquinone plastoquinone (complex I) - - - - - - - - - - - - Proton_antipo_M DYD1_k127_5463017_3 215803.DB30_3927 1.874e-05 57.0 COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria 28221|Deltaproteobacteria T ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA,PAS_9,Reg_prop,Response_reg,Y_Y_Y DYD1_k127_5463017_2 1307436.PBF_00435 6.551e-28 117.0 COG0640@1|root,COG0640@2|Bacteria,1VBHV@1239|Firmicutes,4HMJ1@91061|Bacilli,1ZHAQ@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_20 DYD1_k127_5463017_1 558169.AGAV01000005_gene2214 1.015e-49 185.0 COG0346@1|root,COG0346@2|Bacteria,1V48E@1239|Firmicutes,4HHUT@91061|Bacilli 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases yurT - - - - - - - - - - - Glyoxalase DYD1_k127_5477262_11 1210884.HG799466_gene12961 1.307e-12 76.0 2CJ67@1|root,32WT5@2|Bacteria,2J0JF@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - DYD1_k127_5477262_5 1239962.C943_03877 2.863e-42 166.0 COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - CarbopepD_reg_2,CarboxypepD_reg,PD40 DYD1_k127_5477262_2 1163407.UU7_14910 4.083e-51 194.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase - - - - - - - - - - - - His_kinase DYD1_k127_5477262_3 861299.J421_0341 1.818e-45 174.0 COG0745@1|root,COG0745@2|Bacteria,1ZUFQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C DYD1_k127_5477262_9 861299.J421_2335 4.797e-24 105.0 COG0239@1|root,COG0239@2|Bacteria,1ZU3U@142182|Gemmatimonadetes 142182|Gemmatimonadetes U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB DYD1_k127_5477262_6 861299.J421_2336 1.312e-39 153.0 COG1993@1|root,COG1993@2|Bacteria 2|Bacteria T acr, cog1993 - - - ko:K09137 - - - - ko00000 - - - DUF190 DYD1_k127_5477262_7 1501230.ET33_12090 3.888e-31 140.0 COG2312@1|root,COG2312@2|Bacteria,1V2D8@1239|Firmicutes,4HGGF@91061|Bacilli,26V4T@186822|Paenibacillaceae 91061|Bacilli S Erythromycin esterase - - - ko:K06880 - - - - ko00000,ko01000,ko01504 - - - Erythro_esteras DYD1_k127_5477262_14 1123242.JH636434_gene4007 1.383e-05 49.0 COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A - - - - - - - - - - - - Sulfatase DYD1_k127_5477262_8 1117108.PAALTS15_25604 8.657e-25 120.0 COG2312@1|root,COG2312@2|Bacteria,1V2D8@1239|Firmicutes,4HGGF@91061|Bacilli,26V4T@186822|Paenibacillaceae 91061|Bacilli S Erythromycin esterase - - - ko:K06880 - - - - ko00000,ko01000,ko01504 - - - Erythro_esteras DYD1_k127_5477262_12 204669.Acid345_3584 1.638e-11 71.0 COG0346@1|root,COG0346@2|Bacteria,3Y5YF@57723|Acidobacteria,2JNP7@204432|Acidobacteriia 204432|Acidobacteriia E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_5477262_1 749414.SBI_02860 4.294e-77 291.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,2GMNT@201174|Actinobacteria 201174|Actinobacteria U Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,PD40 DYD1_k127_5477262_4 316067.Geob_1099 1.446e-43 172.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,43UDK@69541|Desulfuromonadales 28221|Deltaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N DYD1_k127_5477262_16 292459.STH2603 0.0004116 53.0 2E68U@1|root,330WY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5477262_15 518766.Rmar_0978 0.000131 49.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1FIJ6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD1_k127_5477262_10 861299.J421_2041 4.778e-15 85.0 COG1629@1|root,COG1629@2|Bacteria,1ZTI4@142182|Gemmatimonadetes 142182|Gemmatimonadetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg DYD1_k127_5477262_13 1094184.KWO_0118690 2.079e-06 55.0 COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,1S900@1236|Gammaproteobacteria,1XBP9@135614|Xanthomonadales 135614|Xanthomonadales L DDE superfamily endonuclease - - - - - - - - - - - - DDE_3,HTH_32 DYD1_k127_5477262_0 215803.DB30_2637 1.586e-159 523.0 COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria,2YTX2@29|Myxococcales 28221|Deltaproteobacteria P TrkA-C domain - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C DYD1_k127_5504372_0 926569.ANT_01220 9.197e-246 773.0 COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi 200795|Chloroflexi F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade - 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 DYD1_k127_5504372_17 926569.ANT_01230 5.476e-70 245.0 COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi 200795|Chloroflexi K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA DYD1_k127_5504372_7 196162.Noca_1631 1.504e-133 439.0 COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4DV65@85009|Propionibacteriales 201174|Actinobacteria F Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD1_k127_5504372_2 926569.ANT_01250 6.463e-166 526.0 COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi 200795|Chloroflexi E Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain - - 2.1.3.9 ko:K09065 ko00220,ko01100,ko01230,map00220,map01100,map01230 M00845 R07245 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD1_k127_5504372_8 266117.Rxyl_2848 1.56e-133 432.0 COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4CQAT@84995|Rubrobacteria 84995|Rubrobacteria E Amino acid kinase family - - 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - - AA_kinase DYD1_k127_5504372_5 1521187.JPIM01000030_gene1509 9.323e-151 487.0 COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi 200795|Chloroflexi M ABC transporter substrate-binding protein PnrA-like - - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp DYD1_k127_5504372_4 448385.sce3554 4.317e-154 503.0 COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,42NTY@68525|delta/epsilon subdivisions,2WK4F@28221|Deltaproteobacteria 28221|Deltaproteobacteria S ABC transporter - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran DYD1_k127_5504372_10 1322246.BN4_12721 9.762e-101 342.0 COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42MWE@68525|delta/epsilon subdivisions,2WKIZ@28221|Deltaproteobacteria,2MGK9@213115|Desulfovibrionales 28221|Deltaproteobacteria S Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 DYD1_k127_5504372_11 1158318.ATXC01000001_gene666 1.119e-94 332.0 COG1079@1|root,COG1079@2|Bacteria 2|Bacteria S Belongs to the binding-protein-dependent transport system permease family rbsC-2 - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 DYD1_k127_5504372_3 926569.ANT_04670 4.228e-165 529.0 COG0498@1|root,COG0498@2|Bacteria,2G6D6@200795|Chloroflexi 200795|Chloroflexi E Pyridoxal-phosphate dependent enzyme - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_5504372_6 926569.ANT_04660 1.012e-149 479.0 COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi 200795|Chloroflexi M PFAM Glycosyl transferase family 2 - - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 DYD1_k127_5504372_1 926569.ANT_04650 7.112e-243 772.0 COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi 200795|Chloroflexi E Pyridoxal-phosphate dependent enzyme - - - - - - - - - - - - PALP DYD1_k127_5504372_22 926569.ANT_04640 2.228e-42 161.0 COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi 200795|Chloroflexi S Protein conserved in bacteria - - - - - - - - - - - - - DYD1_k127_5504372_34 1123504.JQKD01000041_gene2844 1.576e-24 113.0 COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,4AG36@80864|Comamonadaceae 28216|Betaproteobacteria P CutA1 divalent ion tolerance protein cutA GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - ko:K03926 - - - - ko00000 - - - CutA1 DYD1_k127_5504372_28 1122221.JHVI01000014_gene1365 3.399e-28 119.0 COG0454@1|root,COG0456@2|Bacteria,1WK4D@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K FR47-like protein - - 2.3.1.82 ko:K18816 - - - - br01600,ko00000,ko01000,ko01504 - - - Acetyltransf_1 DYD1_k127_5504372_40 1270193.JARP01000005_gene3824 1.047e-09 66.0 COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,1I3NC@117743|Flavobacteriia,2NVVE@237|Flavobacterium 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 DYD1_k127_5504372_20 765420.OSCT_0574 1.044e-54 196.0 COG2050@1|root,COG2050@2|Bacteria,2G9ZQ@200795|Chloroflexi,377IT@32061|Chloroflexia 32061|Chloroflexia Q Thioesterase superfamily - - - - - - - - - - - - 4HBT DYD1_k127_5504372_12 358396.C445_18396 1.213e-88 300.0 COG2057@1|root,arCOG05316@2157|Archaea,2XW2C@28890|Euryarchaeota,23U50@183963|Halobacteria 183963|Halobacteria I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD1_k127_5504372_9 224325.AF_1199 2.862e-133 435.0 COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi 183980|Archaeoglobi I Coenzyme A transferase - - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD1_k127_5504372_33 497964.CfE428DRAFT_6673 5.318e-25 113.0 COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM RNP-1 like RNA-binding protein - - - - - - - - - - - - RRM_1 DYD1_k127_5504372_37 1121405.dsmv_2025 1.29e-13 73.0 COG3478@1|root,COG3478@2|Bacteria,1P0EH@1224|Proteobacteria,431E0@68525|delta/epsilon subdivisions,2WWIK@28221|Deltaproteobacteria,2MNXS@213118|Desulfobacterales 28221|Deltaproteobacteria S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - - - - - - - - - - - DYD1_k127_5504372_25 1382315.JPOI01000001_gene2414 5.341e-41 165.0 COG0454@1|root,COG0456@2|Bacteria,1VC1N@1239|Firmicutes,4HJT0@91061|Bacilli,1WGJE@129337|Geobacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 DYD1_k127_5504372_38 1121918.ARWE01000001_gene3111 4.026e-11 70.0 2FH6M@1|root,34912@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4203) - - - - - - - - - - - - DUF4203 DYD1_k127_5504372_26 926550.CLDAP_16180 6.768e-41 158.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase,Glyoxalase_2 DYD1_k127_5504372_16 1122223.KB890701_gene2224 9.458e-77 268.0 COG0454@1|root,COG0456@2|Bacteria,1WMPD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K acetyltransferase - - - - - - - - - - - - Acetyltransf_10,FR47 DYD1_k127_5504372_21 402777.KB235903_gene687 5.226e-46 171.0 COG3153@1|root,COG3153@2|Bacteria 2|Bacteria S transferase activity, transferring acyl groups - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_5504372_31 981369.JQMJ01000003_gene7088 3.704e-27 124.0 COG3467@1|root,COG3467@2|Bacteria,2GSII@201174|Actinobacteria,2NIMB@228398|Streptacidiphilus 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx DYD1_k127_5504372_27 351160.RCIX1720 3.723e-35 139.0 COG2832@1|root,arCOG07680@2157|Archaea 2157|Archaea S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 DYD1_k127_5504372_19 1501230.ET33_17595 1.741e-56 203.0 COG1247@1|root,COG1247@2|Bacteria,1VJ3A@1239|Firmicutes,4HRVQ@91061|Bacilli 91061|Bacilli M Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_5504372_30 1279017.AQYJ01000024_gene1153 1.969e-27 115.0 COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria,46BQS@72275|Alteromonadaceae 1236|Gammaproteobacteria K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N DYD1_k127_5504372_23 292459.STH1288 2.488e-41 156.0 2ERAK@1|root,33IW8@2|Bacteria,1VNK2@1239|Firmicutes,257CY@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_5504372_42 1370125.AUWT01000024_gene5561 0.000267 51.0 COG3206@1|root,COG3206@2|Bacteria,2GPMH@201174|Actinobacteria,236VJ@1762|Mycobacteriaceae 201174|Actinobacteria M Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 DYD1_k127_5504372_15 1232410.KI421428_gene1030 4.76e-79 271.0 COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 DYD1_k127_5504372_41 410359.Pcal_0555 1.91e-09 69.0 COG0382@1|root,arCOG00476@2157|Archaea,2XQNM@28889|Crenarchaeota 28889|Crenarchaeota H PFAM UbiA prenyltransferase - - 2.5.1.42 ko:K17105 ko00564,map00564 - R04520 RC01171 ko00000,ko00001,ko01000 - - - UbiA DYD1_k127_5504372_18 935840.JAEQ01000006_gene2481 8.328e-62 236.0 COG2518@1|root,COG2518@2|Bacteria,1R1ZR@1224|Proteobacteria,2TZ7U@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 DYD1_k127_5504372_13 867845.KI911784_gene458 3.775e-82 291.0 COG1819@1|root,COG1819@2|Bacteria,2G865@200795|Chloroflexi,375NW@32061|Chloroflexia 32061|Chloroflexia CG PFAM glycosyl transferase, family 28 - - 2.4.1.173 ko:K05841 - - - - ko00000,ko01000,ko01003 - GT1 - Glyco_transf_28,UDPGT DYD1_k127_5504372_43 367299.JOEE01000006_gene856 0.0008363 50.0 COG3603@1|root,COG3603@2|Bacteria 2|Bacteria S ACT domain - - - - - - - - - - - - - DYD1_k127_5504372_29 207954.MED92_11479 7.661e-28 115.0 COG2329@1|root,COG2329@2|Bacteria,1NDM8@1224|Proteobacteria,1SA90@1236|Gammaproteobacteria,1XQ9F@135619|Oceanospirillales 135619|Oceanospirillales S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - - DYD1_k127_5504372_24 448385.sce2190 5.039e-41 162.0 COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,42SGK@68525|delta/epsilon subdivisions,2WPDI@28221|Deltaproteobacteria,2YVW1@29|Myxococcales 28221|Deltaproteobacteria S Alpha/beta hydrolase family - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_4,Abhydrolase_5,DLH DYD1_k127_5504372_36 498761.HM1_2022 3.007e-14 78.0 COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia 186801|Clostridia T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg DYD1_k127_5504372_14 285514.JNWO01000002_gene5046 3.149e-79 273.0 COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria 201174|Actinobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_5504372_32 1385518.N798_03110 4.238e-25 108.0 2DRYE@1|root,33DPC@2|Bacteria,2IS24@201174|Actinobacteria,4FHPE@85021|Intrasporangiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_5504652_10 926550.CLDAP_30050 3.935e-17 82.0 COG0745@1|root,COG0745@2|Bacteria 926550.CLDAP_30050|- T phosphorelay signal transduction system - - - ko:K07670 ko02020,map02020 M00461 - - ko00000,ko00001,ko00002,ko02022 - - - - DYD1_k127_5504652_11 91464.S7335_647 1.022e-14 82.0 COG1357@1|root,COG5635@1|root,COG1357@2|Bacteria,COG5635@2|Bacteria,1G7PE@1117|Cyanobacteria,1H0RN@1129|Synechococcus 1117|Cyanobacteria T low-complexity proteins - - - - - - - - - - - - Pentapeptide DYD1_k127_5504652_8 926569.ANT_22100 5.105e-19 97.0 COG0839@1|root,COG0839@2|Bacteria 2|Bacteria C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD1_k127_5504652_9 926569.ANT_22090 5.705e-18 94.0 COG1006@1|root,COG1006@2|Bacteria 2|Bacteria P Multisubunit Na H antiporter MnhC subunit mnhC - 1.6.5.3 ko:K00340,ko:K05567 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Oxidored_q2 DYD1_k127_5504652_0 926569.ANT_22080 4.228e-219 693.0 COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi 926569.ANT_22080|- CP NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - - - - - - - - - - - - DYD1_k127_5504652_2 926569.ANT_22070 1.392e-149 488.0 COG0651@1|root,COG0651@2|Bacteria 2|Bacteria CP ATP synthesis coupled electron transport mrpD - 1.6.5.3 ko:K00342,ko:K00343,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M,Proton_antipo_N DYD1_k127_5504652_4 926569.ANT_22050 3.405e-68 237.0 COG3260@1|root,COG3260@2|Bacteria,2G8XX@200795|Chloroflexi 200795|Chloroflexi C NADH ubiquinone oxidoreductase, 20 Kd subunit echC - - ko:K14088 - - - - ko00000 - - - Oxidored_q6 DYD1_k127_5504652_7 926569.ANT_22040 6.63e-21 98.0 COG0852@1|root,COG0852@2|Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - 1.6.5.3 ko:K00332,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa DYD1_k127_5504652_1 926569.ANT_22030 8.182e-188 593.0 COG3261@1|root,COG3261@2|Bacteria,2G8BA@200795|Chloroflexi 200795|Chloroflexi C Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - ko:K14090 - - - - ko00000 - - - Complex1_49kDa,NiFeSe_Hases DYD1_k127_5504652_3 926569.ANT_22020 2.537e-128 417.0 COG1005@1|root,COG1005@2|Bacteria 2|Bacteria C quinone binding nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_5504652_5 926569.ANT_22010 5.605e-29 131.0 COG1143@1|root,COG1143@2|Bacteria,2G9SP@200795|Chloroflexi 200795|Chloroflexi C 4Fe-4S binding domain - - - ko:K14091 - - - - ko00000 - - - Fer4 DYD1_k127_5517562_0 926569.ANT_15780 4.808e-268 835.0 COG1032@1|root,COG1032@2|Bacteria,2G5SI@200795|Chloroflexi 200795|Chloroflexi C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - Radical_SAM DYD1_k127_5517562_1 926550.CLDAP_36180 4.552e-123 406.0 COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi 200795|Chloroflexi M Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.23 ko:K13019 ko00520,map00520 - R09600 RC00290 ko00000,ko00001,ko01000,ko01005 - - - Epimerase_2 DYD1_k127_5552428_9 1382356.JQMP01000003_gene2370 0.0001859 46.0 COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,27Y0Z@189775|Thermomicrobia 189775|Thermomicrobia K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind DYD1_k127_5552428_4 926569.ANT_03490 1.69e-72 255.0 COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi 200795|Chloroflexi M Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 DYD1_k127_5552428_2 926569.ANT_03500 1.25e-101 336.0 COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD1_k127_5552428_5 926569.ANT_03510 3.663e-72 248.0 COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi 200795|Chloroflexi J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF DYD1_k127_5552428_3 926569.ANT_31010 2.758e-98 325.0 COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the reversible phosphorylation of UMP to UDP pyrH GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD1_k127_5552428_6 926569.ANT_31020 3.677e-66 231.0 COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi 200795|Chloroflexi J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD1_k127_5552428_1 926569.ANT_31030 5.209e-105 350.0 COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi 200795|Chloroflexi J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 DYD1_k127_5552428_8 1121324.CLIT_13c02410 4.593e-28 118.0 COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,25TW8@186804|Peptostreptococcaceae 186801|Clostridia S Thioesterase superfamily - - 3.1.2.29 ko:K18700 - - - - ko00000,ko01000 - - - 4HBT DYD1_k127_5552428_7 926569.ANT_25150 5.071e-29 119.0 COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi 200795|Chloroflexi I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS DYD1_k127_5552428_0 926569.ANT_25160 1.871e-115 382.0 COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi 200795|Chloroflexi S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_5560217_3 1038860.AXAP01000107_gene4558 1.312e-34 135.0 COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2U0UX@28211|Alphaproteobacteria,3JWP8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 DYD1_k127_5560217_1 1205680.CAKO01000038_gene1610 5.224e-127 413.0 COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TUAN@28211|Alphaproteobacteria,2JQIU@204441|Rhodospirillales 204441|Rhodospirillales G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 DYD1_k127_5560217_0 318996.AXAZ01000082_gene3074 1.735e-144 472.0 COG1653@1|root,COG1653@2|Bacteria,1R5NT@1224|Proteobacteria,2TTRQ@28211|Alphaproteobacteria,3JSBR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 DYD1_k127_5560217_2 443598.AUFA01000017_gene7348 1.205e-39 151.0 COG1653@1|root,COG1653@2|Bacteria,1R5NT@1224|Proteobacteria,2TTRQ@28211|Alphaproteobacteria,3JSBR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 DYD1_k127_5567020_3 518766.Rmar_1679 7.158e-22 104.0 COG1977@1|root,COG1977@2|Bacteria,4NVU9@976|Bacteroidetes,1FJK9@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H ThiS family - - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD1_k127_5567020_2 926569.ANT_22750 4.306e-35 143.0 2DMUR@1|root,32TTD@2|Bacteria,2G72Z@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4395) - - - - - - - - - - - - DUF4395 DYD1_k127_5567020_4 926569.ANT_22740 3.052e-18 91.0 COG0526@1|root,COG0526@2|Bacteria,2G7HX@200795|Chloroflexi 200795|Chloroflexi CO COG0526, thiol-disulfide isomerase and thioredoxins - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_5567020_1 1303518.CCALI_00532 1.606e-150 486.0 COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria 2|Bacteria H Mo-molybdopterin cofactor metabolic process moeB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 ko:K03148,ko:K03636,ko:K21029,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF,ThiS DYD1_k127_5567020_5 5062.CADAORAP00010143 3.907e-10 72.0 COG0823@1|root,2QPTW@2759|Eukaryota,38RVS@33154|Opisthokonta,3NZ8B@4751|Fungi,3QSE5@4890|Ascomycota 4751|Fungi U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 DYD1_k127_5567020_0 926569.ANT_00850 3.752e-201 637.0 COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi 200795|Chloroflexi E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_5569356_2 309800.C498_02520 2.563e-20 104.0 COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,240TC@183963|Halobacteria 183963|Halobacteria C COG1520 FOG WD40-like repeat - - - - - - - - - - - - PQQ_2,PQQ_3 DYD1_k127_5569356_0 1242864.D187_003310 2.89e-116 383.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales 28221|Deltaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD1_k127_5569356_3 35754.JNYJ01000036_gene3794 5.034e-14 81.0 COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4DAGF@85008|Micromonosporales 201174|Actinobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran DYD1_k127_5569356_1 457429.ABJI02000526_gene6639 2.41e-21 98.0 COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria 201174|Actinobacteria P F420H(2)-dependent quinone reductase - - - - - - - - - - - - F420H2_quin_red DYD1_k127_5577094_2 926550.CLDAP_14320 2.867e-110 366.0 COG0411@1|root,COG0411@2|Bacteria,2G5VI@200795|Chloroflexi 200795|Chloroflexi E PFAM ABC transporter related - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_5577094_0 926550.CLDAP_14310 7.125e-240 758.0 COG1022@1|root,COG1022@2|Bacteria,2G5S9@200795|Chloroflexi 200795|Chloroflexi I PFAM AMP-dependent synthetase and ligase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding DYD1_k127_5577094_4 926550.CLDAP_14300 2.263e-95 327.0 COG0559@1|root,COG0559@2|Bacteria,2G6M5@200795|Chloroflexi 200795|Chloroflexi E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_5577094_1 926550.CLDAP_14290 5.013e-117 386.0 COG4177@1|root,COG4177@2|Bacteria,2G6HP@200795|Chloroflexi 200795|Chloroflexi P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_5577094_5 926550.CLDAP_14280 6.206e-76 272.0 COG0683@1|root,COG0683@2|Bacteria 2|Bacteria E ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_5577094_3 926550.CLDAP_14270 4.09e-107 355.0 COG0410@1|root,COG0410@2|Bacteria,2G654@200795|Chloroflexi 200795|Chloroflexi E PFAM ABC transporter related - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD1_k127_5577094_6 296591.Bpro_5258 6.215e-44 171.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,4ACR6@80864|Comamonadaceae 28216|Betaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.31 ko:K16876 ko00365,ko01120,map00365,map01120 - R02986 RC00004,RC00174 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C DYD1_k127_5588342_2 357808.RoseRS_2972 2.097e-17 81.0 COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia 32061|Chloroflexia C PFAM acyl-CoA dehydrogenase domain protein - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_5588342_1 383372.Rcas_1888 8.227e-154 497.0 COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi,3763W@32061|Chloroflexia 32061|Chloroflexia C PFAM acyl-CoA dehydrogenase domain protein - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_5588342_0 1128421.JAGA01000004_gene2619 1.051e-235 751.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2NQHU@2323|unclassified Bacteria 2|Bacteria I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain fadB - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782,ko:K07516 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 DYD1_k127_5655724_1 926569.ANT_18390 1.446e-42 178.0 COG4485@1|root,COG4485@2|Bacteria,2G6VS@200795|Chloroflexi 200795|Chloroflexi S Bacterial membrane protein, YfhO - - - - - - - - - - - - - DYD1_k127_5655724_0 926569.ANT_18400 3.901e-66 246.0 COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi 200795|Chloroflexi S oligosaccharyl transferase activity - - - - - - - - - - - - - DYD1_k127_5655724_3 196162.Noca_2014 2.743e-13 79.0 COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4DQNN@85009|Propionibacteriales 201174|Actinobacteria S C4-type zinc ribbon domain - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K07164 - - - - ko00000 - - - zf-RING_7 DYD1_k127_5655724_2 749927.AMED_4112 1.957e-13 84.0 COG4886@1|root,COG5635@1|root,COG4886@2|Bacteria,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria,4DY6A@85010|Pseudonocardiales 201174|Actinobacteria T NACHT domain - - - - - - - - - - - - NACHT DYD1_k127_5672772_3 216594.MMAR_2938 1.059e-38 146.0 COG0778@1|root,COG0778@2|Bacteria,2GM9M@201174|Actinobacteria,235BZ@1762|Mycobacteriaceae 201174|Actinobacteria C nitroreductase - - - - - - - - - - - - Nitroreductase DYD1_k127_5672772_8 497964.CfE428DRAFT_5116 2.529e-18 89.0 2942H@1|root,2ZRH9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5672772_6 869210.Marky_1921 2.571e-24 108.0 COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD1_k127_5672772_5 861299.J421_6000 1.055e-26 113.0 COG0789@1|root,COG0789@2|Bacteria,1ZVAN@142182|Gemmatimonadetes 142182|Gemmatimonadetes K MerR, DNA binding - - - ko:K13639 - - - - ko00000,ko03000 - - - - DYD1_k127_5672772_1 436229.JOEH01000013_gene5782 2.19e-57 213.0 COG3217@1|root,COG3217@2|Bacteria,2GND9@201174|Actinobacteria,2NI23@228398|Streptacidiphilus 201174|Actinobacteria S MOSC N-terminal beta barrel domain - - - ko:K07140 - - - - ko00000 - - - MOSC,MOSC_N DYD1_k127_5672772_4 243164.DET1501 5.211e-30 129.0 COG0716@1|root,COG0716@2|Bacteria,2GAZ4@200795|Chloroflexi,34DME@301297|Dehalococcoidia 301297|Dehalococcoidia C Flavodoxin - - - - - - - - - - - - - DYD1_k127_5672772_7 368407.Memar_2263 1.675e-19 94.0 arCOG09456@1|root,arCOG09456@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - DYD1_k127_5672772_0 1499967.BAYZ01000013_gene6438 5.364e-63 218.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase DYD1_k127_5672772_2 1122221.JHVI01000014_gene1365 1.402e-39 153.0 COG0454@1|root,COG0456@2|Bacteria,1WK4D@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K FR47-like protein - - 2.3.1.82 ko:K18816 - - - - br01600,ko00000,ko01000,ko01504 - - - Acetyltransf_1 DYD1_k127_5672772_10 476272.RUMHYD_00036 0.0009897 48.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3XYNG@572511|Blautia 186801|Clostridia S protein conserved in bacteria - - - - - - - - - - - - PG_binding_4,YkuD DYD1_k127_5672772_9 926550.CLDAP_18950 9.871e-12 72.0 2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF4013) - - - - - - - - - - - - DUF4013 DYD1_k127_5702654_4 1121091.AUMP01000007_gene1061 1.804e-27 116.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli 91061|Bacilli P Membrane - - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - CitMHS DYD1_k127_5702654_6 1121028.ARQE01000004_gene1422 3.188e-11 70.0 COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2U4U4@28211|Alphaproteobacteria,2PK5P@255475|Aurantimonadaceae 28211|Alphaproteobacteria T CBS domain - - - ko:K07168 - - - - ko00000 - - - CBS,HPP DYD1_k127_5702654_5 316274.Haur_3438 4.408e-15 80.0 COG0347@1|root,COG0347@2|Bacteria,2G9NA@200795|Chloroflexi 200795|Chloroflexi K Belongs to the P(II) protein family - - - - - - - - - - - - - DYD1_k127_5702654_1 316274.Haur_3439 2.226e-105 356.0 COG0475@1|root,COG0475@2|Bacteria,2G6B0@200795|Chloroflexi,375SB@32061|Chloroflexia 32061|Chloroflexia P PFAM sodium hydrogen exchanger - - - - - - - - - - - - Na_H_Exchanger DYD1_k127_5702654_3 926550.CLDAP_10960 4.576e-47 180.0 COG2030@1|root,COG2030@2|Bacteria,2G966@200795|Chloroflexi 200795|Chloroflexi I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas DYD1_k127_5702654_0 926569.ANT_30500 1.24e-321 1001.0 COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase, family 51 - - - - - - - - - - - - Transgly,Transpeptidase DYD1_k127_5713938_6 479434.Sthe_2346 1.117e-26 116.0 COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 DYD1_k127_5713938_10 1047013.AQSP01000122_gene2224 4.177e-13 83.0 COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria 2|Bacteria M PKD domain - - 3.2.1.157,3.2.1.91 ko:K19668,ko:K20850 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R02886,R11308 RC00799 ko00000,ko00001,ko01000 - GH6,GH82 - Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3 DYD1_k127_5713938_8 344747.PM8797T_15596 2.036e-21 100.0 2BZBR@1|root,32YH6@2|Bacteria,2J41E@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - DYD1_k127_5713938_3 675635.Psed_1943 4.604e-68 251.0 COG1819@1|root,COG1819@2|Bacteria,2GJMF@201174|Actinobacteria,4DZ4T@85010|Pseudonocardiales 201174|Actinobacteria CG Glycosyltransferase family 28 N-terminal domain - - - - - - - - - - - - Glyco_transf_28,UDPGT DYD1_k127_5713938_14 765420.OSCT_1742 9.528e-08 64.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_5713938_12 68260.JOAY01000045_gene1338 5.913e-09 68.0 COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria 201174|Actinobacteria Q ABC transporter (Permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_5713938_5 1242864.D187_007875 2.677e-61 220.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QF5@68525|delta/epsilon subdivisions,2WK2K@28221|Deltaproteobacteria,2YXMZ@29|Myxococcales 28221|Deltaproteobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5713938_7 234267.Acid_0856 1.026e-21 110.0 COG3391@1|root,COG3391@2|Bacteria,3Y5TX@57723|Acidobacteria 57723|Acidobacteria S amine dehydrogenase activity - - - - - - - - - - - - PQQ_2 DYD1_k127_5713938_11 926569.ANT_27460 1.192e-11 70.0 COG2919@1|root,COG2919@2|Bacteria,2G9Q3@200795|Chloroflexi 200795|Chloroflexi D Septum formation initiator - - - - - - - - - - - - DivIC DYD1_k127_5713938_9 1485544.JQKP01000019_gene21 6.169e-20 100.0 COG1070@1|root,COG2827@1|root,COG1070@2|Bacteria,COG2827@2|Bacteria,1MW4A@1224|Proteobacteria,2VI4Z@28216|Betaproteobacteria 28216|Betaproteobacteria G Carbohydrate kinase - - - - - - - - - - - - FGGY_C,FGGY_N DYD1_k127_5713938_0 926569.ANT_22450 2.355e-238 783.0 COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi 200795|Chloroflexi D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge DYD1_k127_5713938_2 926569.ANT_22460 4.726e-74 258.0 COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi 200795|Chloroflexi J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm DYD1_k127_5713938_1 221360.RS9917_05080 1.689e-130 429.0 COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria,1GZS9@1129|Synechococcus 1117|Cyanobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_5713938_4 641491.DND132_1124 1.983e-67 243.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WPYW@28221|Deltaproteobacteria,2MC7X@213115|Desulfovibrionales 28221|Deltaproteobacteria E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_5732287_0 926569.ANT_06070 3.597e-132 433.0 COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi 200795|Chloroflexi F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD1_k127_5732287_1 485913.Krac_12187 4.349e-27 121.0 COG0745@1|root,COG0745@2|Bacteria 485913.Krac_12187|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_5775278_2 926569.ANT_19480 9.38e-29 121.0 COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi 200795|Chloroflexi O PFAM Cytochrome C assembly protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD1_k127_5775278_3 926569.ANT_19460 1.473e-28 127.0 COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi 200795|Chloroflexi O subunit of a heme lyase ccmH - - ko:K02200 - - - - ko00000 - - - CcmH DYD1_k127_5775278_5 1690.BPSG_1585 1.139e-05 54.0 COG1520@1|root,COG1520@2|Bacteria,2IBDZ@201174|Actinobacteria,4CYUA@85004|Bifidobacteriales 201174|Actinobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - PQQ_2,zinc_ribbon_2 DYD1_k127_5775278_0 926560.KE387025_gene3982 1.373e-113 376.0 COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5775278_1 926560.KE387025_gene3981 4.098e-84 298.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity devC - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_5775278_4 926560.KE387025_gene3980 1.291e-09 61.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity devC - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_5794202_1 1499967.BAYZ01000119_gene3216 1.185e-115 382.0 COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria 2|Bacteria G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_2,PPDK_N,Response_reg DYD1_k127_5794202_0 1191523.MROS_2800 4.321e-185 590.0 COG0334@1|root,COG0334@2|Bacteria 2|Bacteria E glutamate dehydrogenase [NAD(P)+] activity gluD GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 ko:K00260,ko:K00261,ko:K00262 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.gdhA ELFV_dehydrog,ELFV_dehydrog_N DYD1_k127_5794202_3 479434.Sthe_2666 1.7e-59 218.0 COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,27YDQ@189775|Thermomicrobia 189775|Thermomicrobia K Transcriptional regulatory protein, C terminal - - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_5794202_4 479434.Sthe_1940 2.559e-56 215.0 COG0642@1|root,COG2205@2|Bacteria,2GAAW@200795|Chloroflexi,27Z8B@189775|Thermomicrobia 189775|Thermomicrobia T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA DYD1_k127_5794202_2 44056.XP_009035087.1 1.023e-80 276.0 COG0525@1|root,KOG0432@2759|Eukaryota 2759|Eukaryota J valyl-tRNA aminoacylation - GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061458,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 DYD1_k127_5835359_3 96561.Dole_3065 1.255e-26 110.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales 28221|Deltaproteobacteria K PFAM Cold-shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD1_k127_5835359_2 1267535.KB906767_gene409 3.152e-27 127.0 COG0613@1|root,COG0613@2|Bacteria 2|Bacteria Q PHP domain protein - - - - - - - - - - - - CarboxypepD_reg DYD1_k127_5835359_1 317936.Nos7107_3521 1.358e-32 136.0 2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HS5Z@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5835359_0 1123242.JH636435_gene1922 0.0 1029.0 COG0474@1|root,COG0474@2|Bacteria,2IXV7@203682|Planctomycetes 203682|Planctomycetes P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD1_k127_5835359_5 795666.MW7_2671 1.21e-15 79.0 COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,1K4I0@119060|Burkholderiaceae 28216|Betaproteobacteria M Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 DYD1_k127_5835359_4 1454004.AW11_03245 5.17e-23 108.0 2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,2WGJ3@28216|Betaproteobacteria 28216|Betaproteobacteria M Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 DYD1_k127_5838369_2 926569.ANT_24760 2.444e-20 99.0 2DSXF@1|root,33HTI@2|Bacteria,2G9HW@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF3341) - - - - - - - - - - - - DUF3341 DYD1_k127_5838369_0 926569.ANT_24770 1.466e-158 517.0 COG5557@1|root,COG5557@2|Bacteria,2G68D@200795|Chloroflexi 200795|Chloroflexi C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD DYD1_k127_5838369_1 269799.Gmet_1811 8.695e-102 336.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,43TY6@69541|Desulfuromonadales 28221|Deltaproteobacteria C 4Fe-4S dicluster domain actB - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_585492_10 926569.ANT_28860 1.316e-32 138.0 COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi 200795|Chloroflexi L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII DYD1_k127_585492_0 479434.Sthe_1848 4.173e-98 348.0 COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi,27YYU@189775|Thermomicrobia 189775|Thermomicrobia S Transporter associated domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 DYD1_k127_585492_1 926569.ANT_07440 2.309e-89 304.0 COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi 200795|Chloroflexi S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo DYD1_k127_585492_15 66429.JOFL01000016_gene82 2.345e-08 64.0 COG0470@1|root,COG1674@1|root,COG0470@2|Bacteria,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria 201174|Actinobacteria D DNA segregation ATPase FtsK SpoIIIE and related - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE DYD1_k127_585492_9 192952.MM_0502 3.045e-51 188.0 COG0251@1|root,arCOG01630@2157|Archaea,2Y700@28890|Euryarchaeota,2NAY2@224756|Methanomicrobia 224756|Methanomicrobia J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD1_k127_585492_7 926569.ANT_30440 3.02e-55 206.0 COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi 200795|Chloroflexi L TIGRFAM DNA polymerase III, delta' subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta DYD1_k127_585492_12 926569.ANT_30450 2.516e-29 124.0 28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_585492_3 247490.KSU1_C1426 2.904e-87 299.0 COG0042@1|root,COG0042@2|Bacteria,2IYI5@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - - - - - - - - - - Dus DYD1_k127_585492_4 926569.ANT_02540 9.829e-79 277.0 COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi 200795|Chloroflexi L DNA polymerase III, delta prime subunit holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C DYD1_k127_585492_11 926569.ANT_28350 2.822e-32 128.0 COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi 200795|Chloroflexi S PFAM Stage V sporulation protein S - - - ko:K06416 - - - - ko00000 - - - SpoVS DYD1_k127_585492_2 926569.ANT_28360 6.826e-88 304.0 COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi 200795|Chloroflexi F PFAM deoxynucleoside kinase - - - - - - - - - - - - dNK DYD1_k127_585492_5 926569.ANT_31760 5.463e-75 258.0 COG1428@1|root,COG1428@2|Bacteria 2|Bacteria F Deoxynucleoside kinase dgk - 2.7.1.113 ko:K15518 ko00230,map00230 - R01967 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HPPK,dNK DYD1_k127_585492_6 304371.MCP_0966 1.71e-65 235.0 COG0863@1|root,arCOG00115@2157|Archaea,2Y8E2@28890|Euryarchaeota 28890|Euryarchaeota L DNA methylase - - - - - - - - - - - - N6_N4_Mtase DYD1_k127_585492_13 926569.ANT_09380 1.195e-17 88.0 28XMW@1|root,2ZJIW@2|Bacteria,2G9GS@200795|Chloroflexi 926569.ANT_09380|- - - - - - - - - - - - - - - - DYD1_k127_5872384_1 926569.ANT_08300 8.143e-88 297.0 COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB1 - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 DYD1_k127_5872384_3 1128421.JAGA01000002_gene139 1.058e-47 177.0 COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iAF987.Gmet_3353 Complex1_30kDa DYD1_k127_5872384_0 926569.ANT_08320 2.811e-181 579.0 COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa DYD1_k127_5872384_2 926569.ANT_08330 1.14e-54 196.0 COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi 200795|Chloroflexi C PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit - - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx DYD1_k127_5872384_4 926569.ANT_08340 4.181e-18 87.0 COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB DYD1_k127_5887239_0 1463845.JOIG01000005_gene3542 7.262e-07 63.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - - DYD1_k127_5926914_2 926569.ANT_19880 3.521e-32 129.0 COG0809@1|root,COG0809@2|Bacteria,2G5UZ@200795|Chloroflexi 200795|Chloroflexi J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth DYD1_k127_5926914_3 1382359.JIAL01000001_gene2056 6.287e-09 63.0 29WS1@1|root,30ID4@2|Bacteria,3Y5IE@57723|Acidobacteria,2JK0W@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 DYD1_k127_5926914_0 926569.ANT_19870 1.672e-143 471.0 COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi 200795|Chloroflexi L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N DYD1_k127_5926914_1 935567.JAES01000029_gene2735 3.148e-91 304.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales 135614|Xanthomonadales G 6-phosphogluconate dehydrogenase gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 DYD1_k127_5958284_1 1408322.JHYK01000005_gene497 1.892e-07 52.0 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,27J0Y@186928|unclassified Lachnospiraceae 186801|Clostridia D Peptidase family M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 DYD1_k127_5958284_0 926569.ANT_07430 7.26e-100 338.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi 200795|Chloroflexi M Peptidoglycan-binding LysM - - - - - - - - - - - - LysM,Peptidase_M23,SH3_3 DYD1_k127_5971840_3 1123024.AUII01000052_gene3914 4.864e-66 232.0 COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales 201174|Actinobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_31 DYD1_k127_5971840_0 234267.Acid_5969 1.286e-175 561.0 COG0076@1|root,COG0076@2|Bacteria,3Y365@57723|Acidobacteria 57723|Acidobacteria E Pyridoxal-dependent decarboxylase conserved domain - - - - - - - - - - - - Pyridoxal_deC DYD1_k127_5971840_8 926569.ANT_04790 4.53e-29 124.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - 3.5.1.104 ko:K07273,ko:K22278 - - - - ko00000,ko01000 - - - Glyco_hydro_25,LysM DYD1_k127_5971840_6 926569.ANT_04780 3.622e-44 168.0 COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi 200795|Chloroflexi L PFAM NUDIX hydrolase - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX DYD1_k127_5971840_7 926569.ANT_04540 3.22e-34 137.0 COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi 200795|Chloroflexi J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 DYD1_k127_5971840_5 404589.Anae109_2816 9.287e-52 194.0 COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_5971840_1 926569.ANT_04560 5.98e-88 298.0 COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi 200795|Chloroflexi M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race DYD1_k127_5971840_4 997346.HMPREF9374_3407 1.365e-59 224.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,27BG3@186824|Thermoactinomycetaceae 91061|Bacilli F 5'-nucleotidase, C-terminal domain yunD - - - - - - - - - - - 5_nucleotid_C,Metallophos DYD1_k127_5971840_2 926550.CLDAP_32580 4.504e-66 233.0 COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi 200795|Chloroflexi L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD1_k127_597903_5 1128421.JAGA01000001_gene2449 1.028e-67 244.0 COG3842@1|root,COG3842@2|Bacteria 2|Bacteria P ATPase activity cysA - 3.6.3.25 ko:K02045 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.1,3.A.1.6.3 - - ABC_tran,TOBE_2,TOBE_3 DYD1_k127_597903_0 1128421.JAGA01000001_gene2450 1.219e-128 438.0 COG1613@1|root,COG1613@2|Bacteria,2NQGY@2323|unclassified Bacteria 2|Bacteria P Bacterial extracellular solute-binding protein subI GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K02048 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - iJN678.sbpA SBP_bac_11 DYD1_k127_597903_1 1128421.JAGA01000001_gene2451 4.429e-91 308.0 COG4208@1|root,COG4208@2|Bacteria 2|Bacteria P ATPase-coupled sulfate transmembrane transporter activity cysW GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02046,ko:K02047 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - iPC815.YPO3013 BPD_transp_1 DYD1_k127_597903_3 316274.Haur_0257 2.667e-78 273.0 COG4208@1|root,COG4208@2|Bacteria 2|Bacteria P ATPase-coupled sulfate transmembrane transporter activity cysW GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02046,ko:K02047 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - iPC815.YPO3013 BPD_transp_1 DYD1_k127_597903_7 1122176.KB903571_gene4788 4.057e-58 210.0 COG0705@1|root,COG0705@2|Bacteria,4NS52@976|Bacteroidetes,1IQMD@117747|Sphingobacteriia 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid DYD1_k127_597903_9 118166.JH976537_gene1838 9.162e-28 115.0 2BZBR@1|root,32YH6@2|Bacteria,1G92Y@1117|Cyanobacteria,1HCZ4@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_597903_4 1499967.BAYZ01000184_gene4575 6.479e-68 255.0 COG0618@1|root,COG0618@2|Bacteria 2|Bacteria S phosphoesterase RecJ domain protein - - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD1_k127_597903_11 1267600.JFGT01000003_gene2006 3.183e-20 93.0 COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,3W180@53335|Pantoea 1236|Gammaproteobacteria S Belongs to the UPF0337 (CsbD) family yjbJ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - CsbD DYD1_k127_597903_12 1122176.KB903598_gene4727 4.79e-08 60.0 COG5487@1|root,COG5487@2|Bacteria 2|Bacteria S UPF0391 membrane protein - - - - - - - - - - - - DUF1328 DYD1_k127_597903_2 330214.NIDE1491 2.44e-83 307.0 COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae 40117|Nitrospirae T Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - ABC_sub_bind,HATPase_c,HisKA_3,PAS_9 DYD1_k127_597903_6 56780.SYN_01953 3.743e-62 229.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales 28221|Deltaproteobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_597903_8 1128421.JAGA01000003_gene2960 1.024e-31 129.0 COG0517@1|root,COG0517@2|Bacteria,2NS4F@2323|unclassified Bacteria 2|Bacteria S Domain in cystathionine beta-synthase and other proteins. yhcV - - - - - - - - - - - CBS DYD1_k127_597903_10 479434.Sthe_2550 2.044e-21 98.0 COG0762@1|root,COG0762@2|Bacteria,2G9JK@200795|Chloroflexi,27ZAJ@189775|Thermomicrobia 189775|Thermomicrobia S integral membrane protein - - - - - - - - - - - - - DYD1_k127_605846_3 926569.ANT_28370 7.294e-56 199.0 COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi 200795|Chloroflexi O PFAM DSBA oxidoreductase - - - - - - - - - - - - Thioredoxin_4 DYD1_k127_605846_8 1504822.CCNO01000009_gene1704 2.62e-11 71.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf - - 3.4.21.107 ko:K04771,ko:K08372 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_605846_5 83406.HDN1F_22870 3.203e-38 149.0 COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,1S7RK@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp DYD1_k127_605846_9 357808.RoseRS_0300 5.617e-09 64.0 COG1943@1|root,COG1943@2|Bacteria,2G88H@200795|Chloroflexi,377A5@32061|Chloroflexia 32061|Chloroflexia L Transposase IS200 like - - - - - - - - - - - - - DYD1_k127_605846_4 1301098.PKB_4072 9.977e-42 163.0 COG0596@1|root,COG0596@2|Bacteria,1RDP1@1224|Proteobacteria,1S67D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 DYD1_k127_605846_6 309801.trd_1980 9.313e-27 127.0 COG3568@1|root,COG3568@2|Bacteria,2G7ER@200795|Chloroflexi,27XU2@189775|Thermomicrobia 189775|Thermomicrobia S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos DYD1_k127_605846_2 28532.XP_010549296.1 1.347e-139 458.0 COG0076@1|root,KOG1383@2759|Eukaryota,37IN2@33090|Viridiplantae,3G8PT@35493|Streptophyta,3HU66@3699|Brassicales 35493|Streptophyta E Pyridoxal-dependent decarboxylase conserved domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006629,GO:0006643,GO:0006665,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016020,GO:0016042,GO:0030149,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046466,GO:0071704,GO:1901564,GO:1901565,GO:1901575 4.1.2.27 ko:K01634 ko00600,ko01100,ko04071,map00600,map01100,map04071 M00100 R02464,R06516 RC00264,RC00721,RC01266 ko00000,ko00001,ko00002,ko01000 - - - Pyridoxal_deC DYD1_k127_605846_1 483219.LILAB_22120 1.843e-170 550.0 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2Z0QK@29|Myxococcales 28221|Deltaproteobacteria G FGGY family of carbohydrate kinases, N-terminal domain - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N DYD1_k127_605846_7 748727.CLJU_c14450 5.377e-23 111.0 2EXYB@1|root,33R7F@2|Bacteria,1VRIG@1239|Firmicutes,24D3X@186801|Clostridia,36HQK@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF429) - - - - - - - - - - - - DUF429 DYD1_k127_605846_0 926569.ANT_02040 1.831e-245 779.0 COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi 200795|Chloroflexi C Belongs to the aldehyde dehydrogenase family - - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh DYD1_k127_6090945_2 357808.RoseRS_4002 3.055e-115 374.0 COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,376F8@32061|Chloroflexia 32061|Chloroflexia E PFAM ABC transporter related - - - ko:K09972 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran DYD1_k127_6090945_0 926569.ANT_11040 1.154e-215 683.0 COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,2G9NH@200795|Chloroflexi 200795|Chloroflexi F Phosphoribulokinase / Uridine kinase family - - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK DYD1_k127_6090945_3 292459.STH214 1.454e-114 388.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 186801|Clostridia I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 ko:K00074,ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N DYD1_k127_6090945_4 1121090.KB894700_gene3295 3.525e-103 346.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4IU6J@91061|Bacilli 91061|Bacilli I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - 3HCDH,3HCDH_N,ECH_1,ECH_2 DYD1_k127_6090945_1 1122223.KB890698_gene786 8.266e-158 503.0 COG3396@1|root,COG3396@2|Bacteria,1WI17@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC DYD1_k127_6090945_8 937777.Deipe_0819 7.886e-31 128.0 COG3460@1|root,COG3460@2|Bacteria,1WIFI@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus Q phenylacetic acid degradation paaB - - ko:K02610 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - PaaB DYD1_k127_6090945_5 649638.Trad_1147 8.362e-80 275.0 COG3396@1|root,COG3396@2|Bacteria,1WI5D@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S TIGRFAM Phenylacetate-CoA oxygenase, PaaI subunit paaC - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC DYD1_k127_6090945_7 926560.KE387023_gene1972 2.487e-48 179.0 COG2151@1|root,COG2151@2|Bacteria,1WJW0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P DYD1_k127_6090945_9 1347086.CCBA010000008_gene1301 5.805e-20 94.0 COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes,4HJC6@91061|Bacilli,1ZHQD@1386|Bacillus 91061|Bacilli S EthD domain ethD - - - - - - - - - - - EthD DYD1_k127_6090945_6 485913.Krac_0962 1.754e-64 241.0 COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi 200795|Chloroflexi KLT Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,Pkinase DYD1_k127_6118510_0 525904.Tter_2776 1.485e-67 255.0 COG2730@1|root,COG3386@1|root,COG5492@1|root,COG2730@2|Bacteria,COG3386@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - 3.1.1.15 ko:K13874,ko:K22217 ko00053,ko01100,map00053,map01100 - R02526 RC00537 ko00000,ko00001,ko01000 - - - SGL DYD1_k127_6126565_0 926569.ANT_28040 1.279e-125 410.0 COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi 200795|Chloroflexi M PFAM basic membrane lipoprotein - - - ko:K07335 - - - - ko00000 - - - Bmp DYD1_k127_6126565_1 326427.Cagg_3761 0.0008117 51.0 COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi,375H7@32061|Chloroflexia 32061|Chloroflexia M PFAM basic membrane lipoprotein - - - ko:K07335 - - - - ko00000 - - - Bmp DYD1_k127_6131710_1 264732.Moth_1428 5.722e-44 166.0 COG2014@1|root,COG2014@2|Bacteria,1V22I@1239|Firmicutes,24GWQ@186801|Clostridia,42HYX@68295|Thermoanaerobacterales 186801|Clostridia S Putative heavy-metal chelation - - - ko:K09138 - - - - ko00000 - - - DUF364,DUF4213 DYD1_k127_6131710_0 670487.Ocepr_1935 1.143e-110 370.0 COG0433@1|root,COG1196@1|root,COG0433@2|Bacteria,COG1196@2|Bacteria,1WM64@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus D nuclear chromosome segregation - - - - - - - - - - - - - DYD1_k127_613560_1 926569.ANT_05360 4.768e-155 497.0 COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi 200795|Chloroflexi BK Radical_SAM C-terminal domain - - 2.3.1.48 ko:K07739 - - - - ko00000,ko01000,ko03016,ko03036 - - - Acetyltransf_1,Radical_SAM,Radical_SAM_C DYD1_k127_613560_5 660470.Theba_2008 6.719e-43 173.0 COG1409@1|root,COG1409@2|Bacteria,2GDAI@200918|Thermotogae 200918|Thermotogae P PFAM Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos DYD1_k127_613560_3 926569.ANT_13140 2.194e-51 188.0 COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi 200795|Chloroflexi K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_613560_4 926569.ANT_13160 8.386e-46 181.0 COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi 200795|Chloroflexi M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin DYD1_k127_613560_0 926569.ANT_01830 0.0 1403.0 COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi 200795|Chloroflexi L TIGRFAM DNA polymerase III, alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon DYD1_k127_613560_2 1122622.ATWJ01000014_gene448 6.968e-154 501.0 COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4FG41@85021|Intrasporangiaceae 201174|Actinobacteria G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK DYD1_k127_613681_1 926569.ANT_14510 0.0 1079.0 COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi 200795|Chloroflexi C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_613681_2 926569.ANT_05200 1.328e-202 646.0 COG0664@1|root,COG0664@2|Bacteria,2G63K@200795|Chloroflexi 200795|Chloroflexi T - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - - DYD1_k127_613681_5 926569.ANT_14490 9.126e-163 525.0 COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi 200795|Chloroflexi C CO dehydrogenase flavoprotein C-terminal domain - - - - - - - - - - - - CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 DYD1_k127_613681_6 926569.ANT_14480 6.69e-96 321.0 COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi 200795|Chloroflexi O XdhC Rossmann domain - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI DYD1_k127_613681_14 552811.Dehly_1438 2.215e-25 113.0 2DNS7@1|root,32YWC@2|Bacteria 2|Bacteria S S23 ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_613681_0 926569.ANT_14470 0.0 1470.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G5NF@200795|Chloroflexi 200795|Chloroflexi C COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs xdh - - ko:K12528 ko00450,map00450 - R07229 RC02420 ko00000,ko00001 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD1_k127_613681_15 1236902.ANAS01000019_gene4322 2.837e-13 80.0 COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4EFM5@85012|Streptosporangiales 201174|Actinobacteria C CO dehydrogenase flavoprotein C-terminal domain cutM - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_613681_13 926569.ANT_25970 8.923e-31 132.0 COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi 200795|Chloroflexi Q Thioesterase superfamily protein - - - - - - - - - - - - 4HBT DYD1_k127_613681_3 926569.ANT_14450 2.889e-179 569.0 COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi 200795|Chloroflexi C Luciferase-like monooxygenase - - 1.5.98.2 ko:K00320 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R04464 RC01607 ko00000,ko00001,ko00002,ko01000 - - - Bac_luciferase DYD1_k127_613681_11 926569.ANT_14440 5.834e-43 173.0 COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi 200795|Chloroflexi H Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor cofC GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 ko:K14941 ko00680,ko01120,map00680,map01120 M00378 R09397 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CofC DYD1_k127_613681_7 926569.ANT_14430 2.66e-92 322.0 COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM LPPG domain protein containing protein cofD - 2.7.8.28 ko:K11212 ko00680,ko01120,map00680,map01120 M00378 R09398 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - UPF0052 DYD1_k127_613681_10 795666.MW7_3328 2.608e-59 211.0 COG0778@1|root,COG0778@2|Bacteria,1Q9EX@1224|Proteobacteria,2W39R@28216|Betaproteobacteria 28216|Betaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase DYD1_k127_613681_12 1187851.A33M_3396 3.063e-34 135.0 COG3467@1|root,COG3467@2|Bacteria 2|Bacteria T pyridoxamine 5'-phosphate - - - ko:K07005 - - - - ko00000 - - - Putative_PNPOx,Pyridox_ox_2 DYD1_k127_613681_8 926569.ANT_14410 2.507e-83 285.0 COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM F420-dependent oxidoreductase - - 6.3.2.31,6.3.2.34 ko:K12234 ko00680,ko01120,map00680,map01120 M00378 R09399,R09400 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000 - - - F420_ligase DYD1_k127_613681_9 926569.ANT_14400 5.238e-72 252.0 COG2085@1|root,COG2085@2|Bacteria,2G7DD@200795|Chloroflexi 200795|Chloroflexi S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD1_k127_613681_4 926569.ANT_14390 7.182e-178 569.0 COG0402@1|root,COG0402@2|Bacteria,2G7M9@200795|Chloroflexi 200795|Chloroflexi F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD1_k127_614600_4 926569.ANT_15860 2.66e-93 324.0 COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi 200795|Chloroflexi M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - DUF2298,PMT_2,TPR_16,TPR_19,TPR_8 DYD1_k127_614600_3 926569.ANT_15870 4.045e-127 434.0 COG1287@1|root,COG1287@2|Bacteria 2|Bacteria S oligosaccharyl transferase activity - - 2.4.99.18 ko:K07151 ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141 M00072 R04216,R05976 RC00005,RC00482 ko00000,ko00001,ko00002,ko01000,ko01003 - GT66 - PMT_2 DYD1_k127_614600_9 2074.JNYD01000004_gene5009 1.182e-27 122.0 COG2227@1|root,COG2227@2|Bacteria,2HJ6J@201174|Actinobacteria,4E7I0@85010|Pseudonocardiales 201174|Actinobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 DYD1_k127_614600_6 926569.ANT_15880 2.085e-62 239.0 COG0500@1|root,COG2226@2|Bacteria,2G8SE@200795|Chloroflexi 200795|Chloroflexi Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 DYD1_k127_614600_2 324602.Caur_3475 2.052e-127 430.0 COG0438@1|root,COG0438@2|Bacteria,2G84C@200795|Chloroflexi,375HH@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Methyltransf_11 DYD1_k127_614600_10 926569.ANT_15900 2.105e-22 109.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_614600_1 326427.Cagg_2762 9.821e-131 425.0 COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia 32061|Chloroflexia M short-chain dehydrogenase reductase SDR - - 5.1.3.10 ko:K12454 ko00520,map00520 - R04266 RC00528 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd DYD1_k127_614600_0 926569.ANT_15910 1.21e-300 930.0 COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi 200795|Chloroflexi J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C DYD1_k127_614600_5 926569.ANT_15920 1.779e-76 265.0 COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi 200795|Chloroflexi J Ribosomal RNA methyltransferase RrmJ FtsJ - - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 DYD1_k127_614600_8 1123248.KB893337_gene2566 1.246e-29 121.0 COG5470@1|root,COG5470@2|Bacteria,4NUEC@976|Bacteroidetes,1IZ1F@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 DYD1_k127_614600_7 1382306.JNIM01000001_gene1819 1.204e-31 131.0 COG3509@1|root,COG3509@2|Bacteria,2G91Y@200795|Chloroflexi 200795|Chloroflexi Q Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd DYD1_k127_6166767_7 324602.Caur_0821 2.492e-27 120.0 COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi,376RT@32061|Chloroflexia 32061|Chloroflexia M PFAM secretion protein HlyD family protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 DYD1_k127_6166767_2 765420.OSCT_1741 1.019e-78 272.0 COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi 200795|Chloroflexi P Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_6166767_15 1267534.KB906754_gene2664 0.0001912 50.0 2BM1T@1|root,32FIQ@2|Bacteria,3Y809@57723|Acidobacteria,2JMYM@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - DYD1_k127_6166767_5 315750.BPUM_3683 1.045e-34 139.0 COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli,1ZFP4@1386|Bacillus 91061|Bacilli K Acetyltransferase yycN - - - - - - - - - - - Acetyltransf_1 DYD1_k127_6166767_13 435830.HMPREF0045_01397 6.015e-08 63.0 COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4D4AP@85005|Actinomycetales 201174|Actinobacteria K CarD family transcriptional regulator carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF DYD1_k127_6166767_8 497964.CfE428DRAFT_6673 1.325e-25 112.0 COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM RNP-1 like RNA-binding protein - - - - - - - - - - - - RRM_1 DYD1_k127_6166767_4 926549.KI421517_gene2117 1.082e-37 148.0 COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,47Q73@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_6166767_3 555079.Toce_2076 2.17e-42 166.0 COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,42GT3@68295|Thermoanaerobacterales 186801|Clostridia K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_6166767_6 448385.sce5383 1.14e-31 131.0 2EA6W@1|root,334BM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6166767_11 1538295.JY96_01920 3.503e-09 60.0 COG5649@1|root,COG5649@2|Bacteria,1N9MN@1224|Proteobacteria,2VX32@28216|Betaproteobacteria,1KMMK@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD1_k127_6166767_9 926560.KE387023_gene1206 7.748e-20 95.0 COG5649@1|root,COG5649@2|Bacteria 2|Bacteria E Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD1_k127_6166767_14 661478.OP10G_0314 2.29e-05 48.0 COG0412@1|root,COG0412@2|Bacteria 2|Bacteria Q carboxymethylenebutenolidase activity MA20_42490 - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_6166767_12 324602.Caur_2628 1.373e-08 58.0 COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi 200795|Chloroflexi Q PFAM Dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_6166767_10 743719.PaelaDRAFT_0743 3.467e-18 93.0 COG2074@1|root,COG2074@2|Bacteria,1UJSS@1239|Firmicutes,4HQUT@91061|Bacilli,272FT@186822|Paenibacillaceae 91061|Bacilli G phosphotransferase activity, carboxyl group as acceptor - - - - - - - - - - - - - DYD1_k127_6166767_0 485913.Krac_1540 3.184e-106 349.0 COG0262@1|root,COG0262@2|Bacteria 2|Bacteria H dihydrofolate reductase activity - - - - - - - - - - - - RibD_C DYD1_k127_6166767_1 395961.Cyan7425_1861 2.265e-88 302.0 COG0604@1|root,COG0604@2|Bacteria,1GQ2K@1117|Cyanobacteria 1117|Cyanobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - - DYD1_k127_617182_10 326427.Cagg_2774 2.479e-08 57.0 COG2331@1|root,COG2331@2|Bacteria,2G9QZ@200795|Chloroflexi,377TZ@32061|Chloroflexia 32061|Chloroflexia S regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 DYD1_k127_617182_12 1045856.EcWSU1_02111 4.159e-05 53.0 COG0457@1|root,COG1520@1|root,COG2373@1|root,COG2911@1|root,COG2931@1|root,COG0457@2|Bacteria,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q von willebrand factor, type A lapA - - ko:K12549 - - - - ko00000 - - - Big_3_2,Cadherin_3,Calx-beta,HemolysinCabind,VCBS,VWA,VWA_2 DYD1_k127_617182_11 452652.KSE_11840 1.143e-06 58.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,2M2HZ@2063|Kitasatospora 201174|Actinobacteria M TIGRFAM YD repeat protein - - - - - - - - - - - - PT-HINT,RHS_repeat DYD1_k127_617182_4 926569.ANT_08420 4.466e-136 449.0 COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M DYD1_k127_617182_2 926569.ANT_08410 2.048e-222 699.0 COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi 200795|Chloroflexi C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M DYD1_k127_617182_1 926569.ANT_08400 3.705e-235 746.0 COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi 200795|Chloroflexi CP NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N DYD1_k127_617182_8 383372.Rcas_3385 9.575e-32 127.0 COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi,375TW@32061|Chloroflexia 32061|Chloroflexia F NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD1_k127_617182_7 316274.Haur_3215 6.556e-40 156.0 COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi,375QH@32061|Chloroflexia 32061|Chloroflexia C Belongs to the complex I subunit 6 family - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD1_k127_617182_6 926569.ANT_08370 1.651e-77 261.0 COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338,ko:K05580 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 DYD1_k127_617182_5 671143.DAMO_2695 1.874e-114 383.0 COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_617182_0 926569.ANT_08350 1.768e-287 924.0 COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria 2|Bacteria C ATP synthesis coupled electron transport nuoG GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD1_k127_617182_3 926569.ANT_08340 1.17e-182 578.0 COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB DYD1_k127_6172689_2 926569.ANT_20820 2.246e-70 247.0 COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi 200795|Chloroflexi J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD1_k127_6172689_3 526227.Mesil_3163 6.516e-51 188.0 COG0580@1|root,COG0580@2|Bacteria,1WKA2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP DYD1_k127_6172689_0 604331.AUHY01000040_gene92 7.857e-206 651.0 COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N DYD1_k127_6172689_4 485913.Krac_9318 1.497e-08 66.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 DYD1_k127_6172689_1 357808.RoseRS_3299 2.227e-141 465.0 COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi,3750F@32061|Chloroflexia 32061|Chloroflexia C BFD domain protein 2Fe-2S -binding domain protein - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,Fer2_BFD DYD1_k127_6172689_5 1144310.PMI07_005563 0.0002681 51.0 COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2TSRQ@28211|Alphaproteobacteria,4BDNF@82115|Rhizobiaceae 28211|Alphaproteobacteria C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_binding_2 DYD1_k127_6268111_4 926569.ANT_00590 1.247e-42 158.0 COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi 200795|Chloroflexi J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 DYD1_k127_6268111_5 926569.ANT_00600 9.296e-21 95.0 COG0291@1|root,COG0291@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p DYD1_k127_6268111_2 926569.ANT_02480 3.311e-69 238.0 COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi 200795|Chloroflexi J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N DYD1_k127_6268111_6 509191.AEDB02000021_gene3095 3.571e-06 58.0 COG0348@1|root,COG0348@2|Bacteria,1V143@1239|Firmicutes,25BBT@186801|Clostridia,3WS5K@541000|Ruminococcaceae 186801|Clostridia C 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_10,Fer4_5,Fer4_9 DYD1_k127_6268111_0 765420.OSCT_2998 6.366e-124 411.0 COG1251@1|root,COG1251@2|Bacteria,2G6YZ@200795|Chloroflexi 200795|Chloroflexi C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - FHA,Pyr_redox_2 DYD1_k127_6268111_3 765420.OSCT_2999 1.406e-51 190.0 COG0492@1|root,COG0492@2|Bacteria 2|Bacteria C ferredoxin-NADP+ reductase activity - - - - - - - - - - - - FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding DYD1_k127_6268111_1 765420.OSCT_3000 5.903e-85 305.0 COG0484@1|root,COG0484@2|Bacteria 2|Bacteria O heat shock protein binding - - - - - - - - - - - - Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7 DYD1_k127_6268111_7 1112216.JH594425_gene1790 4.095e-06 60.0 COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2UBMV@28211|Alphaproteobacteria,2K6P2@204457|Sphingomonadales 204457|Sphingomonadales O heat shock protein binding - - - - - - - - - - - - - DYD1_k127_627513_3 765952.PUV_01000 0.0001616 46.0 COG4980@1|root,COG4980@2|Bacteria 2|Bacteria D gas vesicle protein XK27_07760 - - - - - - - - - - - YtxH DYD1_k127_627513_2 309801.trd_A0420 6.606e-11 64.0 COG3526@1|root,COG3526@2|Bacteria,2GA5K@200795|Chloroflexi,27ZBE@189775|Thermomicrobia 189775|Thermomicrobia O Rdx family - - - ko:K07401 - - - - ko00000 - - - Rdx DYD1_k127_627513_0 429009.Adeg_0380 8.798e-51 186.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,42GII@68295|Thermoanaerobacterales 186801|Clostridia J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase DYD1_k127_627513_1 926569.ANT_18920 2.198e-15 79.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion - - - - - - - - - - - - Band_7 DYD1_k127_628870_17 309801.trd_A0702 6.031e-13 71.0 COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi,27Y6W@189775|Thermomicrobia 189775|Thermomicrobia S Putative peptidoglycan binding domain - - - - - - - - - - - - DUF1028,PG_binding_2 DYD1_k127_628870_8 926569.ANT_16620 2.863e-62 223.0 COG0647@1|root,COG0647@2|Bacteria,2G6G5@200795|Chloroflexi 200795|Chloroflexi G PFAM Haloacid dehalogenase domain protein hydrolase - - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like DYD1_k127_628870_3 926569.ANT_16630 8.02e-121 399.0 COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi 200795|Chloroflexi J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM DYD1_k127_628870_5 1157490.EL26_06940 3.875e-109 372.0 COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,4HA0D@91061|Bacilli 91061|Bacilli S Zn-dependent proteases and their inactivated homologs - - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD DYD1_k127_628870_10 1157490.EL26_06945 4.443e-57 218.0 COG0312@1|root,COG0312@2|Bacteria,1V3G5@1239|Firmicutes 1239|Firmicutes S Putative modulator of DNA gyrase - - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD DYD1_k127_628870_4 926569.ANT_04130 3.514e-109 369.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi 200795|Chloroflexi T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,GAF_3,HATPase_c,HisKA_3 DYD1_k127_628870_6 1248917.ANFX01000013_gene1541 2.394e-65 230.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,2K1ZB@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim DYD1_k127_628870_16 926569.ANT_15230 9.174e-18 87.0 COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi 200795|Chloroflexi J ribosomal protein L28 rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 DYD1_k127_628870_14 926569.ANT_15240 4.325e-32 130.0 COG1302@1|root,COG1302@2|Bacteria,2G76I@200795|Chloroflexi 200795|Chloroflexi S Asp23 family, cell envelope-related function - - - - - - - - - - - - Asp23 DYD1_k127_628870_2 926569.ANT_15250 5.094e-186 602.0 COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi 200795|Chloroflexi S PFAM Dak phosphatase - - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 DYD1_k127_628870_12 926550.CLDAP_35860 7.929e-39 164.0 COG1307@1|root,COG1307@2|Bacteria,2G6P2@200795|Chloroflexi 200795|Chloroflexi S PFAM DegV family protein - - - - - - - - - - - - DegV DYD1_k127_628870_13 227882.SAV_5490 4.361e-34 149.0 COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria 201174|Actinobacteria S DegV family - - - - - - - - - - - - DegV DYD1_k127_628870_1 926569.ANT_15270 3.105e-262 832.0 COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi 200795|Chloroflexi L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge DYD1_k127_628870_7 926569.ANT_15280 2.306e-64 229.0 COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi 200795|Chloroflexi F Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD1_k127_628870_9 926569.ANT_15290 2.201e-59 209.0 COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi 200795|Chloroflexi C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - - - - - - - - - - - DYD1_k127_628870_0 926569.ANT_25410 2.493e-273 849.0 COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase DYD1_k127_628870_11 926569.ANT_03760 1.657e-43 161.0 COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi 200795|Chloroflexi S PFAM Roadblock LC7 family protein - - - ko:K07131 - - - - ko00000 - - - Robl_LC7 DYD1_k127_628870_15 309801.trd_0111 1.171e-26 113.0 COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi,27YEY@189775|Thermomicrobia 189775|Thermomicrobia J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM DYD1_k127_6297947_2 926569.ANT_23340 6.812e-135 443.0 COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi 200795|Chloroflexi M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_6297947_3 926569.ANT_23330 2.949e-121 418.0 COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi 200795|Chloroflexi M Penicillin-binding protein, dimerisation domain ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase DYD1_k127_6297947_4 926569.ANT_23310 2.685e-114 376.0 COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi 200795|Chloroflexi J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 DYD1_k127_6297947_7 926569.ANT_23300 5.572e-40 153.0 COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi 200795|Chloroflexi K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ DYD1_k127_6297947_0 926569.ANT_23280 9.769e-181 581.0 COG0520@1|root,COG0520@2|Bacteria,2G85X@200795|Chloroflexi 200795|Chloroflexi H Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD1_k127_6297947_6 710111.FraQA3DRAFT_0723 2.652e-68 244.0 COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4EU0N@85013|Frankiales 201174|Actinobacteria Q Esterase PHB depolymerase - - - ko:K03932 - - - - ko00000 - CE1 - Esterase_phd DYD1_k127_6297947_13 345341.KUTG_04140 1.512e-09 64.0 2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_6297947_11 926569.ANT_28110 6.648e-26 109.0 COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi 200795|Chloroflexi S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 DYD1_k127_6297947_10 926569.ANT_19040 2.253e-26 123.0 2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_6297947_5 926569.ANT_19030 4.577e-74 258.0 COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi 200795|Chloroflexi S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 DYD1_k127_6297947_9 1128421.JAGA01000003_gene3128 1.886e-36 148.0 2BBY6@1|root,325GN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6297947_12 765910.MARPU_14465 1.463e-09 71.0 COG1874@1|root,COG1874@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Cellulase,Glyco_hydro_35,Glyco_hydro_42,Glyco_hydro_42M,Glyco_hydro_cc,Tail_P2_I DYD1_k127_6297947_1 926569.ANT_19600 8.45e-142 459.0 COG2189@1|root,COG2189@2|Bacteria,2G7K2@200795|Chloroflexi 200795|Chloroflexi L PFAM DNA methylase N-4 N-6 domain protein - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase DYD1_k127_6302793_10 316067.Geob_2517 2.177e-16 80.0 28HKD@1|root,2Z7V8@2|Bacteria,1MXBM@1224|Proteobacteria 1224|Proteobacteria S Type II restriction enzyme - - 3.1.21.4 ko:K01155 - - - - ko00000,ko01000,ko02048 - - - - DYD1_k127_6302793_11 1348657.M622_18015 1.772e-13 76.0 COG2199@1|root,COG3706@2|Bacteria,1NEHB@1224|Proteobacteria,2W2SA@28216|Betaproteobacteria 28216|Betaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_6302793_7 926569.ANT_20740 3.722e-60 213.0 COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_6302793_0 926569.ANT_15410 3.646e-288 912.0 COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi 200795|Chloroflexi L PFAM Exonuclease, RNase T and DNA polymerase III - - 2.7.7.7,3.6.4.12 ko:K02342,ko:K03722 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,RNase_T DYD1_k127_6302793_4 926569.ANT_20860 1.178e-72 250.0 COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi 200795|Chloroflexi J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD1_k127_6302793_2 926569.ANT_20880 8.964e-87 301.0 COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi 200795|Chloroflexi S DinB superfamily - - - - - - - - - - - - DinB_2 DYD1_k127_6302793_5 42256.RradSPS_1185 3.792e-69 238.0 COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria 201174|Actinobacteria V Intracellular protease - - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI DYD1_k127_6302793_6 926569.ANT_16600 6.685e-69 251.0 COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi 200795|Chloroflexi D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N DYD1_k127_6302793_3 926569.ANT_16610 9.804e-87 292.0 COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi 200795|Chloroflexi O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease DYD1_k127_6302793_1 1382306.JNIM01000001_gene3912 6.891e-161 525.0 COG1219@1|root,COG1219@2|Bacteria,2G661@200795|Chloroflexi 200795|Chloroflexi O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX DYD1_k127_6302793_9 986075.CathTA2_3059 4.04e-23 106.0 COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli 91061|Bacilli S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028,PG_binding_2 DYD1_k127_6317205_4 1200792.AKYF01000001_gene3905 7.109e-11 64.0 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,26Y8P@186822|Paenibacillaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD DYD1_k127_6317205_3 243231.GSU0549 1.214e-12 72.0 COG2227@1|root,COG2227@2|Bacteria,1QXN3@1224|Proteobacteria,43C46@68525|delta/epsilon subdivisions,2X7EM@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_11 DYD1_k127_6317205_5 457425.XNR_2535 0.0001618 50.0 COG1051@1|root,COG1051@2|Bacteria,2IK42@201174|Actinobacteria 201174|Actinobacteria F Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - ATP_bind_2,NUDIX DYD1_k127_6317205_0 1206732.BAGD01000281_gene6696 9.263e-62 218.0 COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4FUV9@85025|Nocardiaceae 201174|Actinobacteria H RibD C-terminal domain - - - ko:K03088 - - - - ko00000,ko03021 - - - RibD_C DYD1_k127_6317205_1 696281.Desru_0063 4.889e-51 187.0 COG4978@1|root,COG4978@2|Bacteria,1VC6Q@1239|Firmicutes,25DFV@186801|Clostridia 186801|Clostridia KT Bacterial transcription activator, effector binding domain - - - - - - - - - - - - GyrI-like DYD1_k127_6317205_2 1123248.KB893316_gene4667 1.949e-33 133.0 COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1ITAW@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD1_k127_6321942_3 469383.Cwoe_1903 9.442e-60 220.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2GNXA@201174|Actinobacteria 201174|Actinobacteria C I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B) ctaC GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM DYD1_k127_6321942_0 118173.KB235914_gene641 2.908e-216 683.0 COG0843@1|root,COG0843@2|Bacteria,1G1ME@1117|Cyanobacteria,1H763@1150|Oscillatoriales 1117|Cyanobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 DYD1_k127_6321942_4 357808.RoseRS_2265 2.585e-46 174.0 COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi,375ZR@32061|Chloroflexia 32061|Chloroflexia C PFAM cytochrome c oxidase, subunit III - - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 DYD1_k127_6321942_2 309801.trd_A0395 3.485e-112 397.0 COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia 189775|Thermomicrobia O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - COX15-CtaA,UbiA DYD1_k127_6321942_1 646529.Desaci_0102 2.266e-120 400.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Cytochrome_C554,Multi-haem_cyto DYD1_k127_6321942_9 1121952.ATXT01000013_gene2150 3.188e-05 55.0 2BQYC@1|root,32JVM@2|Bacteria,2HTWK@201174|Actinobacteria,4FSZZ@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_6321942_6 479434.Sthe_0237 1.125e-07 63.0 2E99N@1|root,333HT@2|Bacteria,2GBAU@200795|Chloroflexi,27YK7@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - DYD1_k127_6321942_7 350058.Mvan_3648 1.495e-07 63.0 2EB70@1|root,3357M@2|Bacteria,2I9PW@201174|Actinobacteria,237JT@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_6321942_5 926569.ANT_05270 4.265e-37 147.0 COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi 200795|Chloroflexi S Electron transport protein SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD1_k127_643025_3 864702.OsccyDRAFT_4744 5.352e-12 77.0 COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,1H7RX@1150|Oscillatoriales 1117|Cyanobacteria M Mannosyl oligosaccharide glucosidase - - - - - - - - - - - - Glyco_hydro_63 DYD1_k127_643025_1 644968.DFW101_3674 1.043e-23 109.0 COG0500@1|root,COG2226@2|Bacteria,1QZ7W@1224|Proteobacteria,43CZE@68525|delta/epsilon subdivisions,2WYCC@28221|Deltaproteobacteria,2MCB3@213115|Desulfovibrionales 28221|Deltaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 DYD1_k127_643025_2 1168067.JAGP01000001_gene435 2.368e-17 96.0 COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,1SDDS@1236|Gammaproteobacteria,461W1@72273|Thiotrichales 72273|Thiotrichales S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_643025_0 1195246.AGRI_00715 3.793e-119 405.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,469ZI@72275|Alteromonadaceae 1236|Gammaproteobacteria O carbamoyl transferase, NodU family - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N DYD1_k127_644957_0 479434.Sthe_2294 1.152e-255 835.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,27XZV@189775|Thermomicrobia 189775|Thermomicrobia C FAD linked oxidases, C-terminal domain - - - - - - - - - - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17 DYD1_k127_644957_1 926569.ANT_16960 4.861e-166 535.0 COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi 200795|Chloroflexi S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 DYD1_k127_644957_2 1128421.JAGA01000001_gene2396 3.2e-71 256.0 COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria 2|Bacteria S Peptidase M28 - - - - - - - - - - - - Peptidase_M28 DYD1_k127_644957_3 926569.ANT_16920 5.581e-29 119.0 COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs - - 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA DYD1_k127_6453894_3 489825.LYNGBM3L_49830 1.335e-26 116.0 COG2340@1|root,COG2340@2|Bacteria,1G4UZ@1117|Cyanobacteria,1HAAV@1150|Oscillatoriales 1117|Cyanobacteria Q Scp-like extracellular - - - - - - - - - - - - CAP,HemolysinCabind DYD1_k127_6453894_0 926569.ANT_02950 2.32e-172 552.0 COG0402@1|root,COG0402@2|Bacteria,2G6K7@200795|Chloroflexi 200795|Chloroflexi F Amidohydrolase family - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_3 DYD1_k127_6453894_2 1128421.JAGA01000002_gene1877 3.836e-61 232.0 COG0793@1|root,COG0793@2|Bacteria,2NNKC@2323|unclassified Bacteria 2|Bacteria M Tricorn protease C1 domain - - - - - - - - - - - - PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1 DYD1_k127_6453894_1 1047013.AQSP01000100_gene587 3.134e-67 233.0 COG2271@1|root,COG2271@2|Bacteria 2|Bacteria G transmembrane transporter activity - - - - - - - - - - - - MFS_1 DYD1_k127_6490765_9 926569.ANT_28370 3.81e-14 76.0 COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi 200795|Chloroflexi O PFAM DSBA oxidoreductase - - - - - - - - - - - - Thioredoxin_4 DYD1_k127_6490765_6 316274.Haur_0297 3.691e-79 276.0 COG1609@1|root,COG1609@2|Bacteria,2G6DT@200795|Chloroflexi,376ZH@32061|Chloroflexia 32061|Chloroflexia K periplasmic binding protein LacI transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 DYD1_k127_6490765_2 316274.Haur_0298 7.089e-137 451.0 COG1653@1|root,COG1653@2|Bacteria,2G7EJ@200795|Chloroflexi 200795|Chloroflexi G PFAM extracellular solute-binding protein family 1 - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 DYD1_k127_6490765_3 1128421.JAGA01000003_gene3685 3.57e-121 398.0 COG1175@1|root,COG1175@2|Bacteria,2NPAH@2323|unclassified Bacteria 2|Bacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 DYD1_k127_6490765_5 1128421.JAGA01000003_gene3686 7.401e-96 322.0 COG0395@1|root,COG0395@2|Bacteria,2NR1D@2323|unclassified Bacteria 2|Bacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 DYD1_k127_6490765_4 926550.CLDAP_13280 1.045e-109 370.0 COG3534@1|root,COG3534@2|Bacteria,2G8SV@200795|Chloroflexi 200795|Chloroflexi G alpha-L-arabinofuranosidase - - - - - - - - - - - - - DYD1_k127_6490765_0 543632.JOJL01000009_gene6011 0.0 1122.0 COG3459@1|root,COG3459@2|Bacteria,2IAZ0@201174|Actinobacteria,4DHXT@85008|Micromonosporales 201174|Actinobacteria G Putative carbohydrate binding domain - - 2.4.1.20 ko:K00702 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000 - GT36 - Glyco_hydro_36,Glyco_transf_36 DYD1_k127_6490765_1 649639.Bcell_2329 1.04e-310 971.0 COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1ZF4F@1386|Bacillus 91061|Bacilli G Glycosyl hydrolase 36 superfamily, catalytic domain chvB1 - 2.4.1.20,2.4.1.333 ko:K00702,ko:K13688,ko:K21298 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36 DYD1_k127_6490765_8 1123252.ATZF01000002_gene2674 1.884e-27 115.0 COG0640@1|root,COG0640@2|Bacteria,1VAMP@1239|Firmicutes,4HNAJ@91061|Bacilli,27C6K@186824|Thermoactinomycetaceae 91061|Bacilli K Sugar-specific transcriptional regulator TrmB - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 DYD1_k127_6490765_7 1416759.AYMR01000006_gene1355 8.356e-37 145.0 COG3832@1|root,COG3832@2|Bacteria,2GTYS@201174|Actinobacteria,4FQD6@85023|Microbacteriaceae 201174|Actinobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD1_k127_6544572_2 1183438.GKIL_2057 1.432e-31 133.0 COG0451@1|root,COG0451@2|Bacteria,1G2DP@1117|Cyanobacteria 1117|Cyanobacteria M PFAM NAD dependent epimerase dehydratase family dfrA - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase DYD1_k127_6544572_1 644966.Tmar_2131 4.568e-73 255.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,24HM8@186801|Clostridia,3WDT7@538999|Clostridiales incertae sedis 186801|Clostridia I Belongs to the enoyl-CoA hydratase isomerase family - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_6544572_0 926569.ANT_04080 6.22e-257 803.0 COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi 200795|Chloroflexi J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g DYD1_k127_6549001_0 926569.ANT_06580 1.06e-102 341.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K00786 - - - - ko00000,ko01000 - - - Glycos_transf_2 DYD1_k127_6549001_3 926569.ANT_06560 6.402e-70 258.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT,PMT_2 DYD1_k127_6549001_4 926569.ANT_06540 2.916e-69 246.0 COG1215@1|root,COG1215@2|Bacteria,2G8MG@200795|Chloroflexi 200795|Chloroflexi M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_6549001_1 926569.ANT_06530 8.57e-96 322.0 COG2604@1|root,COG2604@2|Bacteria 2|Bacteria S Protein of unknown function DUF115 - - - - - - - - - - - - AbfB,DUF2920,MAF_flag10 DYD1_k127_6549001_2 696747.NIES39_E02470 2.84e-74 274.0 COG1807@1|root,COG1807@2|Bacteria,1G0W2@1117|Cyanobacteria,1H9QQ@1150|Oscillatoriales 1117|Cyanobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_6555740_0 357808.RoseRS_2229 3.168e-84 294.0 COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia 32061|Chloroflexia KLT Serine threonine protein kinase - - - - - - - - - - - - Pkinase DYD1_k127_6555740_1 926569.ANT_30190 1.715e-37 145.0 COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi 200795|Chloroflexi S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 DYD1_k127_6578146_1 391937.NA2_06992 1.421e-157 507.0 COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,2TUUV@28211|Alphaproteobacteria,43NG9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Creatinase/Prolidase N-terminal domain - - - - - - - - - - - - Creatinase_N,Peptidase_M24 DYD1_k127_6578146_0 1380391.JIAS01000004_gene2992 4.195e-200 631.0 COG0665@1|root,COG0665@2|Bacteria,1PERE@1224|Proteobacteria,2U1FT@28211|Alphaproteobacteria 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO DYD1_k127_6578146_2 935840.JAEQ01000006_gene2517 5.132e-61 213.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,43GQB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Ectoine utilization eutB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_6580833_0 1173024.KI912151_gene2204 4.365e-126 410.0 COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria 1117|Cyanobacteria E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 DYD1_k127_6580833_1 1521187.JPIM01000058_gene2537 2.138e-21 99.0 COG2170@1|root,COG2170@2|Bacteria,2G5NR@200795|Chloroflexi,375BI@32061|Chloroflexia 32061|Chloroflexia F ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 DYD1_k127_6580833_2 1267533.KB906738_gene2305 5.287e-05 50.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB DYD1_k127_6686608_6 1122611.KB903941_gene2158 5.975e-05 54.0 COG0517@1|root,COG0517@2|Bacteria,2H4HY@201174|Actinobacteria,4ENRS@85012|Streptosporangiales 201174|Actinobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD1_k127_6686608_4 522306.CAP2UW1_2501 1.494e-20 102.0 COG0604@1|root,COG2905@1|root,COG0604@2|Bacteria,COG2905@2|Bacteria,1MXIK@1224|Proteobacteria,2W1P8@28216|Betaproteobacteria 28216|Betaproteobacteria CT Domain in cystathionine beta-synthase and other proteins. - - 1.3.1.85 ko:K14446 ko00630,ko01120,ko01200,map00630,map01120,map01200 M00373 R09291 RC02481 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N,CBS DYD1_k127_6686608_1 1128421.JAGA01000003_gene3663 1.398e-50 189.0 arCOG06048@1|root,31EJQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6686608_2 158189.SpiBuddy_0632 2.336e-49 191.0 COG1349@1|root,COG1349@2|Bacteria,2JADD@203691|Spirochaetes 203691|Spirochaetes K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR DYD1_k127_6686608_0 1380390.JIAT01000009_gene1063 1.014e-77 284.0 COG2129@1|root,COG2129@2|Bacteria,2IJW1@201174|Actinobacteria,4CQ37@84995|Rubrobacteria 84995|Rubrobacteria S metallophosphoesterase - - - - - - - - - - - - - DYD1_k127_6686608_3 266117.Rxyl_0773 3.388e-46 188.0 COG0531@1|root,COG0531@2|Bacteria,2IPSH@201174|Actinobacteria,4CQHF@84995|Rubrobacteria 84995|Rubrobacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 DYD1_k127_6686608_5 318586.Pden_4916 3.097e-18 91.0 COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2PUDT@265|Paracoccus 28211|Alphaproteobacteria E FAD dependent oxidoreductase central domain sardh - 1.5.3.19 ko:K19191 ko00760,ko01120,map00760,map01120 - R10102 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO,FAO_M,GCV_T,GCV_T_C DYD1_k127_6716265_0 926569.ANT_15860 3.034e-304 983.0 COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi 200795|Chloroflexi M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - DUF2298,PMT_2,TPR_16,TPR_19,TPR_8 DYD1_k127_6716265_2 926569.ANT_27260 4.666e-117 409.0 COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi 200795|Chloroflexi S Uncharacterized membrane protein (DUF2298) - - - - - - - - - - - - DUF2298 DYD1_k127_6716265_6 309801.trd_1272 7.991e-09 68.0 COG1807@1|root,COG1807@2|Bacteria,2GB92@200795|Chloroflexi,27Y63@189775|Thermomicrobia 189775|Thermomicrobia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - DYD1_k127_6716265_3 926569.ANT_10810 5.705e-75 258.0 COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi 200795|Chloroflexi F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin DYD1_k127_6716265_4 867903.ThesuDRAFT_00135 6.679e-27 124.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,3WDTG@538999|Clostridiales incertae sedis 186801|Clostridia I Phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_6716265_1 926569.ANT_16350 1.749e-297 922.0 COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi 200795|Chloroflexi M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS DYD1_k127_6716265_5 1123320.KB889719_gene7264 8.185e-12 66.0 COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria 201174|Actinobacteria O Highly conserved protein containing a thioredoxin domain - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH DYD1_k127_6740011_9 926569.ANT_18430 2.054e-29 121.0 COG1872@1|root,COG1872@2|Bacteria,2G7H4@200795|Chloroflexi 200795|Chloroflexi S Belongs to the UPF0235 family - - - ko:K09131 - - - - ko00000 - - - DUF167 DYD1_k127_6740011_12 926569.ANT_18440 4.717e-15 78.0 COG0762@1|root,COG0762@2|Bacteria 2|Bacteria D integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT DYD1_k127_6740011_6 644966.Tmar_0879 2.869e-54 201.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WCI6@538999|Clostridiales incertae sedis 186801|Clostridia S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N DYD1_k127_6740011_4 926569.ANT_18460 2.065e-66 235.0 COG1496@1|root,COG1496@2|Bacteria,2G6N5@200795|Chloroflexi 200795|Chloroflexi S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 DYD1_k127_6740011_5 926569.ANT_18470 1.426e-63 232.0 COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi 200795|Chloroflexi O Predicted membrane protein (DUF2085) - - - - - - - - - - - - DUF2085 DYD1_k127_6740011_10 1347086.CCBA010000008_gene1244 2.344e-27 129.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZFAP@1386|Bacillus 91061|Bacilli CO COG0526 Thiol-disulfide isomerase and thioredoxins stoA - - - - - - - - - - - AhpC-TSA DYD1_k127_6740011_2 926569.ANT_18490 7.895e-84 284.0 COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi 200795|Chloroflexi O PFAM cytochrome c biogenesis protein, transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD DYD1_k127_6740011_3 926569.ANT_18500 9.87e-67 240.0 COG1376@1|root,COG1376@2|Bacteria 2|Bacteria D ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - DUF5011,YkuD DYD1_k127_6740011_0 926569.ANT_12590 1.235e-312 977.0 COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi 200795|Chloroflexi P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase DYD1_k127_6740011_13 439235.Dalk_3004 3.529e-12 68.0 COG2608@1|root,COG2608@2|Bacteria,1PUDD@1224|Proteobacteria,42XJ7@68525|delta/epsilon subdivisions,2WSKI@28221|Deltaproteobacteria,2MP4U@213118|Desulfobacterales 28221|Deltaproteobacteria P Heavy-metal-associated domain - - - - - - - - - - - - HMA DYD1_k127_6740011_11 926569.ANT_12610 2.723e-26 111.0 COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi 200795|Chloroflexi S Metal-sensitive transcriptional repressor - - - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal DYD1_k127_6740011_1 383372.Rcas_4054 5.8e-166 532.0 COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi 200795|Chloroflexi EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1 DYD1_k127_6740011_7 706587.Desti_3592 7.091e-54 201.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WPJ6@28221|Deltaproteobacteria,2MQG2@213462|Syntrophobacterales 28221|Deltaproteobacteria H molybdenum cofactor moaB - 2.7.7.75 ko:K03638,ko:K03831 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth DYD1_k127_6740011_8 504728.K649_02050 9.958e-33 132.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase ypeA - - ko:K03826 - - - - ko00000,ko01000 - - - Acetyltransf_1 DYD1_k127_6751356_1 1313172.YM304_01520 1.119e-54 197.0 COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4CP5I@84992|Acidimicrobiia 201174|Actinobacteria S ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran DYD1_k127_6751356_2 479434.Sthe_2726 5.136e-12 66.0 COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia 189775|Thermomicrobia O Magnesium chelatase, subunit ChlI - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C DYD1_k127_6769459_6 1121405.dsmv_0979 0.0001228 47.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2MJ8G@213118|Desulfobacterales 28221|Deltaproteobacteria I PFAM AMP-dependent synthetase and ligase - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C DYD1_k127_6769459_0 518766.Rmar_1893 9.086e-96 326.0 COG0006@1|root,COG0006@2|Bacteria,4NJI0@976|Bacteroidetes,1FIUI@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Creatinase/Prolidase N-terminal domain pepQ - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 DYD1_k127_6769459_1 926569.ANT_16080 5.773e-70 253.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_1_like,MFS_3,Sugar_tr DYD1_k127_6769459_2 926569.ANT_23660 4.528e-60 220.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 DYD1_k127_6769459_4 357808.RoseRS_1303 8.681e-06 56.0 COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia 32061|Chloroflexia S domain, Protein - - - - - - - - - - - - - DYD1_k127_6769459_3 357808.RoseRS_3810 1.306e-31 136.0 COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,375U2@32061|Chloroflexia 32061|Chloroflexia K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 DYD1_k127_6771090_3 1038860.AXAP01000098_gene5333 2.29e-11 76.0 COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,SAM_1 DYD1_k127_6771090_1 926569.ANT_04120 1.461e-47 182.0 COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi 200795|Chloroflexi F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like DYD1_k127_6771090_2 926569.ANT_04110 4.718e-38 149.0 COG1399@1|root,COG1399@2|Bacteria 2|Bacteria K metal-binding, possibly nucleic acid-binding protein yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K07040 - - - - ko00000 - - - DUF177 DYD1_k127_6771090_0 926569.ANT_04100 1.905e-145 476.0 COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi 200795|Chloroflexi K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_6780981_7 1122247.C731_3324 1.116e-57 207.0 COG0037@1|root,COG0037@2|Bacteria,2I9QA@201174|Actinobacteria 201174|Actinobacteria D PP-loop family - - 2.8.1.15 ko:K21947 - - - - ko00000,ko01000,ko03016 - - - ATP_bind_3 DYD1_k127_6780981_8 56780.SYN_01967 7.887e-54 199.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2WQ4Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K06879,ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF DYD1_k127_6780981_3 1121405.dsmv_2020 8.499e-74 256.0 COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,42VTP@68525|delta/epsilon subdivisions,2X5B0@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 DYD1_k127_6780981_1 1499967.BAYZ01000119_gene3222 6.124e-163 524.0 COG0174@1|root,COG0174@2|Bacteria,2NNY0@2323|unclassified Bacteria 2|Bacteria E glutamine synthetase glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N DYD1_k127_6780981_9 379066.GAU_2712 2.852e-43 166.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Helix-turn-helix diphteria tox regulatory element - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA DYD1_k127_6780981_5 452637.Oter_2875 1.808e-65 233.0 COG0672@1|root,COG0672@2|Bacteria,46XX5@74201|Verrucomicrobia,3K8IC@414999|Opitutae 414999|Opitutae P Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 DYD1_k127_6780981_10 1121918.ARWE01000001_gene2718 1.612e-17 86.0 COG2005@1|root,COG2005@2|Bacteria 2|Bacteria P Transcriptional regulator - - - ko:K02019,ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.6.2,3.A.1.6.4 - - HTH_1,PBP_like_2 DYD1_k127_6780981_4 926569.ANT_08910 2.799e-66 246.0 COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi 200795|Chloroflexi D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,Pribosyltran,TilS,TilS_C DYD1_k127_6780981_0 926569.ANT_09690 1.759e-163 522.0 COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi 200795|Chloroflexi D TIGRFAM cell shape determining protein, MreB Mrl family - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD1_k127_6780981_6 926569.ANT_09700 3.523e-65 232.0 COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi 200795|Chloroflexi M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC DYD1_k127_6780981_11 744872.Spica_1387 6.179e-06 55.0 COG2891@1|root,COG2891@2|Bacteria,2J89Q@203691|Spirochaetes 203691|Spirochaetes M Rod shape-determining protein (MreD) mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD DYD1_k127_6780981_2 926569.ANT_09720 6.517e-158 520.0 COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi 200795|Chloroflexi M PFAM penicillin-binding protein transpeptidase - - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase DYD1_k127_6782894_11 172045.KS04_05765 0.0007747 43.0 COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,1HX7K@117743|Flavobacteriia,34PKG@308865|Elizabethkingia 976|Bacteroidetes IQ NmrA-like family uxuB - - - - - - - - - - - adh_short,adh_short_C2 DYD1_k127_6782894_4 926569.ANT_06510 1.003e-109 377.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - PMT_2 DYD1_k127_6782894_6 926569.ANT_29590 7.769e-103 345.0 COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi 200795|Chloroflexi M PFAM Glycosyl transferase family 2 - - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 DYD1_k127_6782894_5 926569.ANT_06420 4.956e-103 347.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity ptmF - 2.7.7.82 ko:K18431 ko00520,map00520 - R10182 RC00152 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_6782894_0 926569.ANT_06410 1.678e-200 635.0 COG1887@1|root,COG1887@2|Bacteria 2|Bacteria M Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - - - - - - - - - - Glyphos_transf DYD1_k127_6782894_3 926569.ANT_06400 4.458e-129 419.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2,Glyphos_transf DYD1_k127_6782894_8 926569.ANT_06390 3.519e-88 304.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 DYD1_k127_6782894_9 1521187.JPIM01000048_gene85 8.218e-73 254.0 COG1861@1|root,COG1861@2|Bacteria,2G8I7@200795|Chloroflexi 200795|Chloroflexi M Cytidylyltransferase - - - ko:K07257 - - - - ko00000 - - - CTP_transf_3 DYD1_k127_6782894_7 926569.ANT_06370 1.941e-97 333.0 COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_6782894_2 926569.ANT_06360 4.535e-158 505.0 COG2089@1|root,COG2089@2|Bacteria,2G8PB@200795|Chloroflexi 200795|Chloroflexi M SAF - - 2.5.1.56 ko:K01654 ko00520,ko01100,map00520,map01100 - R01804,R04435 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF DYD1_k127_6782894_10 926569.ANT_06350 6.024e-68 242.0 COG1091@1|root,COG1091@2|Bacteria,2G9A2@200795|Chloroflexi 200795|Chloroflexi M PFAM NAD-dependent epimerase dehydratase - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind DYD1_k127_6782894_1 926569.ANT_06340 1.044e-159 510.0 COG1086@1|root,COG1086@2|Bacteria,2G8BP@200795|Chloroflexi 200795|Chloroflexi M NmrA-like family - - - - - - - - - - - - Polysacc_synt_2 DYD1_k127_6786474_4 32507.XP_006806204.1 9.171e-96 323.0 COG0329@1|root,2QWNS@2759|Eukaryota,399HY@33154|Opisthokonta,3BGNT@33208|Metazoa,3CUM9@33213|Bilateria,481FN@7711|Chordata,48XJ6@7742|Vertebrata,4A1NB@7898|Actinopterygii 33208|Metazoa T 4-hydroxy-2-oxoglutarate aldolase HOGA1 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006081,GO:0006082,GO:0006090,GO:0006520,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008700,GO:0009056,GO:0009058,GO:0009063,GO:0009436,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0016833,GO:0019470,GO:0019471,GO:0019752,GO:0031974,GO:0032787,GO:0033609,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046395,GO:0046487,GO:0046983,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.3.16 ko:K18123 ko00330,ko00630,ko01100,map00330,map00630,map01100 - R00470,R00471 RC00307,RC00308 ko00000,ko00001,ko01000 - - - DHDPS DYD1_k127_6786474_6 706587.Desti_2107 1.555e-59 214.0 COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,2MSBX@213462|Syntrophobacterales 28221|Deltaproteobacteria S Putative cyclase - - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase DYD1_k127_6786474_0 926569.ANT_19690 7.481e-201 634.0 COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M20 - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD1_k127_6786474_7 1095772.CAHH01000028_gene2568 1.862e-43 167.0 COG0235@1|root,COG0235@2|Bacteria,2IJZK@201174|Actinobacteria 201174|Actinobacteria G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II DYD1_k127_6786474_5 742767.HMPREF9456_01816 1.413e-81 284.0 COG0451@1|root,COG0451@2|Bacteria,4P1QM@976|Bacteroidetes,2FX1I@200643|Bacteroidia 976|Bacteroidetes GM NmrA-like family - - - - - - - - - - - - Epimerase DYD1_k127_6786474_3 5691.AAZ11720 2.46e-101 338.0 COG2084@1|root,KOG0409@2759|Eukaryota,3XS8U@5653|Kinetoplastida 5653|Kinetoplastida E 2-hydroxy-3-oxopropionate reductase - - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_6786474_1 926569.ANT_17310 2.548e-152 490.0 COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi 200795|Chloroflexi I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD1_k127_6786474_2 1382306.JNIM01000001_gene3511 4.207e-105 354.0 COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi 200795|Chloroflexi H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM DYD1_k127_6786474_9 1041139.KB902702_gene2359 3.636e-07 59.0 2AKY8@1|root,31BRU@2|Bacteria,1P7PY@1224|Proteobacteria,2UX98@28211|Alphaproteobacteria,4BKEC@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6786474_8 1122609.AUGT01000009_gene2959 1.443e-17 82.0 COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4DPPU@85009|Propionibacteriales 201174|Actinobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD1_k127_6796713_2 1521187.JPIM01000020_gene207 6.239e-55 201.0 COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi,376C6@32061|Chloroflexia 32061|Chloroflexia C The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P DYD1_k127_6796713_3 926569.ANT_16780 1.898e-39 154.0 COG0509@1|root,COG0509@2|Bacteria,2G6XE@200795|Chloroflexi 200795|Chloroflexi E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H DYD1_k127_6796713_1 1382306.JNIM01000001_gene353 1.227e-100 342.0 COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2G66N@200795|Chloroflexi 200795|Chloroflexi M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_6796713_0 926569.ANT_28290 4.22e-124 419.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,2G7T5@200795|Chloroflexi 200795|Chloroflexi P PFAM Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C DYD1_k127_6804123_2 1380355.JNIJ01000050_gene130 8.157e-129 417.0 COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2TTC6@28211|Alphaproteobacteria,3JSJ8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_6804123_1 1038859.AXAU01000028_gene23 1.413e-184 624.0 COG3889@1|root,COG3889@2|Bacteria,1R6EI@1224|Proteobacteria,2UQR6@28211|Alphaproteobacteria,3K2HR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - - - - - - - - - - - DYD1_k127_6804123_0 1038859.AXAU01000028_gene21 1.064e-212 668.0 COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2TTAH@28211|Alphaproteobacteria,3JZY2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_680668_5 357808.RoseRS_2229 1.05e-54 203.0 COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia 32061|Chloroflexia KLT Serine threonine protein kinase - - - - - - - - - - - - Pkinase DYD1_k127_680668_4 1283299.AUKG01000001_gene3236 1.556e-64 246.0 COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRJD@84995|Rubrobacteria 84995|Rubrobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase DYD1_k127_680668_0 309800.C498_18598 7.494e-136 438.0 COG2326@1|root,arCOG03575@2157|Archaea,2XV3H@28890|Euryarchaeota,23UZ1@183963|Halobacteria 183963|Halobacteria F Polyphosphate kinase 2 (PPK2) - - 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 DYD1_k127_680668_1 266117.Rxyl_2933 2.622e-106 366.0 COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria 201174|Actinobacteria S CHAD domain containing protein - - - - - - - - - - - - CHAD,CYTH DYD1_k127_680668_6 266117.Rxyl_2932 1.062e-34 138.0 COG2062@1|root,COG2062@2|Bacteria 2|Bacteria T phosphohistidine phosphatase, SixA sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 DYD1_k127_680668_3 485913.Krac_9227 1.462e-71 252.0 COG0125@1|root,COG0125@2|Bacteria 2|Bacteria F dTDP biosynthetic process tmk GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 ko:K00943,ko:K01585 ko00240,ko00330,ko01100,map00240,map00330,map01100 M00053,M00133 R00566,R02094,R02098 RC00002,RC00299 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c AAA_33,Thymidylate_kin DYD1_k127_680668_2 485913.Krac_9228 3.313e-80 277.0 COG0125@1|root,COG0125@2|Bacteria 2|Bacteria F dTDP biosynthetic process tmk GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 ko:K00560,ko:K00943,ko:K01585 ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523 M00053,M00133 R00566,R02094,R02098,R02101 RC00002,RC00219,RC00299,RC00332 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c AAA_33,Thymidylate_kin DYD1_k127_680668_7 1236976.JCM16418_1512 4.931e-32 139.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,26R0R@186822|Paenibacillaceae 91061|Bacilli FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA DYD1_k127_680668_8 1279038.KB907339_gene1164 2.238e-07 53.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,2JQ2J@204441|Rhodospirillales 204441|Rhodospirillales I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD1_k127_6824119_0 926569.ANT_09480 3.707e-125 411.0 COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE DYD1_k127_6824119_1 926569.ANT_12820 9.584e-36 149.0 COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi 200795|Chloroflexi U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - DYD1_k127_6835717_2 1123320.KB889666_gene3116 0.0006046 44.0 COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria 201174|Actinobacteria H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 DYD1_k127_6835717_0 1042876.PPS_2397 1.262e-79 274.0 COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria 1224|Proteobacteria K amidohydrolase bamU - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_6835717_1 1192124.LIG30_2049 2.785e-63 223.0 COG1028@1|root,COG1028@2|Bacteria,1PP5H@1224|Proteobacteria,2VJ4Y@28216|Betaproteobacteria,1K544@119060|Burkholderiaceae 28216|Betaproteobacteria IQ PFAM short-chain dehydrogenase reductase SDR - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 - - - - - - - - - - adh_short_C2 DYD1_k127_6836555_4 886293.Sinac_6174 8.144e-22 98.0 COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes 203682|Planctomycetes P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA DYD1_k127_6836555_0 926569.ANT_25910 2.217e-147 484.0 COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi 2|Bacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN DYD1_k127_6836555_3 926569.ANT_26250 1.862e-39 151.0 COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi 200795|Chloroflexi S Divergent PAP2 family - - - ko:K09775 - - - - ko00000 - - - DUF212 DYD1_k127_6836555_5 1122604.JONR01000016_gene4380 1.205e-11 67.0 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1X7MG@135614|Xanthomonadales 135614|Xanthomonadales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S DYD1_k127_6836555_1 926569.ANT_26230 3.658e-103 351.0 COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi 200795|Chloroflexi L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 DYD1_k127_6836555_2 479434.Sthe_2029 4.611e-45 168.0 COG1546@1|root,COG1546@2|Bacteria,2G6U8@200795|Chloroflexi,27YG1@189775|Thermomicrobia 189775|Thermomicrobia S Competence-damaged protein - - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA DYD1_k127_6854656_1 204669.Acid345_1535 3.962e-49 179.0 COG1012@1|root,COG1012@2|Bacteria,3Y384@57723|Acidobacteria,2JIA8@204432|Acidobacteriia 204432|Acidobacteriia C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 ko:K00128,ko:K00130,ko:K00146,ko:K10217 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130,map01220 M00038,M00135,M00555,M00569 R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_6854656_0 177437.HRM2_44710 5.696e-158 514.0 COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria 1224|Proteobacteria K iron dependent repressor - - - - - - - - - - - - - DYD1_k127_6854656_2 997296.PB1_03820 1.911e-44 165.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus 91061|Bacilli P Ammonium transporter nrgA - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - iYO844.BSU36510 Ammonium_transp DYD1_k127_6902527_4 1122221.JHVI01000013_gene2748 1.323e-41 156.0 COG1943@1|root,COG1943@2|Bacteria,1WKUD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Transposase - - - - - - - - - - - - - DYD1_k127_6902527_1 926569.ANT_22130 7.211e-217 711.0 COG2730@1|root,COG2730@2|Bacteria 2|Bacteria G polysaccharide catabolic process - - 3.2.1.123 ko:K05991 - - - - ko00000,ko01000 - GH5 - Cellulase DYD1_k127_6902527_2 926569.ANT_04950 1.188e-181 576.0 COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi 200795|Chloroflexi I Belongs to the thiolase family - - - - - - - - - - - - Thiolase_C,Thiolase_N DYD1_k127_6902527_0 383372.Rcas_4326 2.089e-253 794.0 COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia 32061|Chloroflexia I TIGRFAM methylmalonyl-CoA mutase, large subunit - - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase DYD1_k127_6902527_3 926569.ANT_25270 3.573e-114 376.0 COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi 200795|Chloroflexi C Radical SAM domain protein - - 1.97.1.4 ko:K04070 - - - - ko00000,ko01000 - - - Fer4_12,Radical_SAM DYD1_k127_6902527_5 402881.Plav_0616 3.477e-11 64.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2TSD0@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK DYD1_k127_6935425_5 1057002.KB905370_gene3018 3.135e-14 73.0 COG3204@1|root,COG3204@2|Bacteria,1QVA9@1224|Proteobacteria 1224|Proteobacteria L pilus organization - - - - - - - - - - - - - DYD1_k127_6935425_0 1235457.C404_03455 1.081e-155 503.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1K375@119060|Burkholderiaceae 28216|Betaproteobacteria T response regulator zraR - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_6935425_6 404380.Gbem_0454 6.638e-12 69.0 2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,43VXN@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6935425_2 1254432.SCE1572_15860 3.892e-103 353.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2Z3N9@29|Myxococcales 28221|Deltaproteobacteria KT Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_6935425_1 1192034.CAP_3310 4.736e-154 514.0 COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria 28221|Deltaproteobacteria T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg DYD1_k127_6935425_4 1340493.JNIF01000004_gene944 7.815e-50 196.0 COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria 57723|Acidobacteria S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD1_k127_6935425_7 1280947.HY30_13595 5.135e-05 49.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,43WN9@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Penicillin-binding protein 1A mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase DYD1_k127_6935425_3 700598.Niako_5211 6.109e-80 276.0 COG0705@1|root,COG0705@2|Bacteria,4NJG9@976|Bacteroidetes,1J16X@117747|Sphingobacteriia 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid DYD1_k127_6996048_5 411902.CLOBOL_07195 0.0006503 50.0 COG2188@1|root,COG2188@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K03710 - - - - ko00000,ko03000 - - - FCD,GntR DYD1_k127_6996048_3 1210884.HG799470_gene14294 8.281e-17 95.0 COG3378@1|root,COG5545@1|root,COG3378@2|Bacteria,COG5545@2|Bacteria,2J2H5@203682|Planctomycetes 203682|Planctomycetes S Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - - DYD1_k127_6996048_0 429009.Adeg_0412 1.691e-109 379.0 COG1241@1|root,COG4643@1|root,COG1241@2|Bacteria,COG4643@2|Bacteria,1UZJE@1239|Firmicutes,24FKH@186801|Clostridia,42FUS@68295|Thermoanaerobacterales 186801|Clostridia L Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 DYD1_k127_6996048_1 760568.Desku_1404 2.285e-26 114.0 arCOG14851@1|root,2ZTGR@2|Bacteria,1W3VM@1239|Firmicutes,256GJ@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_6996048_2 1121434.AULY01000011_gene1785 1.366e-24 109.0 COG3728@1|root,COG3728@2|Bacteria,1RG2M@1224|Proteobacteria,433MN@68525|delta/epsilon subdivisions,2WXZI@28221|Deltaproteobacteria,2MBVH@213115|Desulfovibrionales 28221|Deltaproteobacteria L PFAM Terminase small subunit - - - ko:K07474 - - - - ko00000 - - - Terminase_2 DYD1_k127_6996048_4 345341.KUTG_00516 1.408e-11 76.0 COG5563@1|root,COG5563@2|Bacteria,2GRWY@201174|Actinobacteria,4ECJT@85010|Pseudonocardiales 201174|Actinobacteria S FG-GAP repeat protein - - - - - - - - - - - - - DYD1_k127_709268_4 926569.ANT_11900 1.861e-61 224.0 COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi 200795|Chloroflexi K Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 DYD1_k127_709268_2 926569.ANT_11910 3.046e-86 294.0 COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi 200795|Chloroflexi T PFAM metallophosphoesterase - - - - - - - - - - - - Metallophos_2 DYD1_k127_709268_6 926569.ANT_31670 3.864e-46 176.0 COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi 200795|Chloroflexi S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE DYD1_k127_709268_5 926569.ANT_31660 1.477e-60 216.0 COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase M22 glycoprotease - - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 DYD1_k127_709268_7 580327.Tthe_2156 1.446e-39 154.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales 186801|Clostridia K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_709268_3 926569.ANT_31640 2.366e-76 261.0 COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi 200795|Chloroflexi L TIGRFAM phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD1_k127_709268_0 383372.Rcas_3083 6.179e-180 573.0 COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi,3756K@32061|Chloroflexia 32061|Chloroflexia M PFAM UDP-glucose GDP-mannose dehydrogenase - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_709268_1 671143.DAMO_2345 9.509e-119 392.0 COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein lspL - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd DYD1_k127_716204_12 1123023.JIAI01000003_gene2586 6.283e-63 233.0 COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria 201174|Actinobacteria E alcohol dehydrogenase - - 1.1.1.303,1.1.1.4 ko:K00004 ko00650,map00650 - R02855,R02946,R10504 RC00205,RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,Glu_dehyd_C DYD1_k127_716204_24 1140002.I570_03805 1.124e-09 71.0 COG0714@1|root,COG4548@1|root,COG0714@2|Bacteria,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HF8H@91061|Bacilli,4B127@81852|Enterococcaceae 91061|Bacilli P von Willebrand factor (vWF) type A domain - - - - - - - - - - - - AAA_5,CobT_C,VWA DYD1_k127_716204_21 1218075.BAYA01000016_gene4380 3.75e-39 157.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,1KGZ6@119060|Burkholderiaceae 28216|Betaproteobacteria S CbbQ/NirQ/NorQ C-terminal - - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C DYD1_k127_716204_8 1089551.KE386572_gene3488 3.668e-91 310.0 COG1529@1|root,COG1529@2|Bacteria,1NPGE@1224|Proteobacteria,2TTCC@28211|Alphaproteobacteria,4BSBB@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Molybdopterin-binding domain of aldehyde dehydrogenase MA20_13970 - - - - - - - - - - - Ald_Xan_dh_C2 DYD1_k127_716204_5 1298858.AUEL01000011_gene5451 4.749e-96 332.0 COG1529@1|root,COG1529@2|Bacteria,1NNFR@1224|Proteobacteria,2TVHX@28211|Alphaproteobacteria,43R41@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase a b hammerhead MA20_13965 - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_716204_16 114615.BRADO4776 1.333e-49 185.0 COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,2TS73@28211|Alphaproteobacteria,3JV5C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain MA20_13960 - 1.2.5.3,1.3.7.9 ko:K03518,ko:K04107 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316,R11168 RC00490,RC02800 ko00000,ko00001,ko01000 - - - Fer2,Fer2_2 DYD1_k127_716204_17 935840.JAEQ01000019_gene2104 4.986e-49 188.0 COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria,43PT0@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM xdhB - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_716204_9 1157490.EL26_00855 9.691e-70 248.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,279RW@186823|Alicyclobacillaceae 91061|Bacilli I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_716204_14 1157490.EL26_00855 6.313e-58 212.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,279RW@186823|Alicyclobacillaceae 91061|Bacilli I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_716204_7 478749.BRYFOR_08002 1.136e-91 314.0 COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,249MG@186801|Clostridia 186801|Clostridia S Beta-lactamase superfamily domain ulaG - - ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 M00550 R07677 RC02793 ko00000,ko00001,ko00002,ko01000 - - - Lactamase_B_2,Lactamase_B_3 DYD1_k127_716204_6 866895.HBHAL_3114 5.106e-95 334.0 COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli,3NEN9@45667|Halobacillus 91061|Bacilli E Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_716204_4 1009370.ALO_14887 4.496e-102 340.0 COG0329@1|root,COG0329@2|Bacteria,1TPSG@1239|Firmicutes,4H3JN@909932|Negativicutes 909932|Negativicutes E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD1_k127_716204_19 515635.Dtur_0646 5.301e-48 182.0 COG3718@1|root,COG3718@2|Bacteria 2|Bacteria G enzyme involved in inositol metabolism iolB - 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08503 RC00541 ko00000,ko00001,ko01000 - - - KduI DYD1_k127_716204_18 324602.Caur_3641 7.458e-49 184.0 COG3622@1|root,COG3622@2|Bacteria 2|Bacteria G hydroxypyruvate isomerase activity hyi - 5.3.1.22,5.3.1.35 ko:K01816,ko:K22131 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 DYD1_k127_716204_13 1297569.MESS2_1190039 1.121e-61 225.0 COG1172@1|root,COG1172@2|Bacteria,1R59D@1224|Proteobacteria,2TUTD@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - - - - - - - - - - BPD_transp_2 DYD1_k127_716204_2 1009370.ALO_16172 1.865e-152 496.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H2EG@909932|Negativicutes 909932|Negativicutes G ABC transporter - - - ko:K17215 ko02010,map02010 M00593 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2 - - ABC_tran DYD1_k127_716204_15 1500257.JQNM01000007_gene1456 5.362e-57 224.0 COG1879@1|root,COG1879@2|Bacteria,1R6AW@1224|Proteobacteria,2U0DK@28211|Alphaproteobacteria,4BCMN@82115|Rhizobiaceae 28211|Alphaproteobacteria G Periplasmic binding protein domain - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 DYD1_k127_716204_10 1500306.JQLA01000018_gene3217 4.004e-66 237.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2V3M3@28211|Alphaproteobacteria,4BINF@82115|Rhizobiaceae 28211|Alphaproteobacteria G Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 DYD1_k127_716204_11 697281.Mahau_2275 7.306e-66 235.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,42GQ3@68295|Thermoanaerobacterales 186801|Clostridia IQ PFAM Short-chain dehydrogenase reductase SDR - - 1.1.1.127,1.1.1.69 ko:K00046,ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 DYD1_k127_716204_20 1122132.AQYH01000003_gene2920 3.633e-46 177.0 COG1802@1|root,COG1802@2|Bacteria,1R6HE@1224|Proteobacteria,2U2J8@28211|Alphaproteobacteria,4BBD5@82115|Rhizobiaceae 28211|Alphaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR DYD1_k127_716204_23 1380390.JIAT01000009_gene846 1.117e-11 77.0 28JQV@1|root,2Z7R2@2|Bacteria,2IBX7@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_716204_0 1128421.JAGA01000003_gene3441 5.607e-198 625.0 COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria 2|Bacteria E Arginosuccinate synthase argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.argG,iSB619.SA_RS04675 Arginosuc_synth DYD1_k127_716204_1 926569.ANT_12430 6.453e-154 499.0 COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi 200795|Chloroflexi E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 DYD1_k127_716204_22 926569.ANT_12420 2.137e-13 75.0 2DRHT@1|root,33BTG@2|Bacteria,2G7I1@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM lysine biosynthesis protein LysW - - - ko:K05826 - M00031,M00763 - - ko00000,ko00001,ko00002 - - - - DYD1_k127_716204_3 926569.ANT_12410 4.663e-124 407.0 COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi 200795|Chloroflexi HJ Belongs to the RimK family - - 6.3.2.43 ko:K05827 ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230 M00031 R09775 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - RimK DYD1_k127_75230_3 264198.Reut_A0410 8.459e-10 68.0 COG1309@1|root,COG1309@2|Bacteria,1RJV4@1224|Proteobacteria,2VSIC@28216|Betaproteobacteria,1KGS0@119060|Burkholderiaceae 28216|Betaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N DYD1_k127_75230_0 765420.OSCT_0044 4.887e-132 435.0 COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,37723@32061|Chloroflexia 32061|Chloroflexia V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD1_k127_75230_2 765420.OSCT_0043 9.291e-46 183.0 COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia 32061|Chloroflexia MV PFAM secretion protein HlyD family protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 DYD1_k127_75230_1 926550.CLDAP_07700 7.487e-100 334.0 COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi 200795|Chloroflexi V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_813589_2 215803.DB30_6124 2.926e-29 121.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2YUZM@29|Myxococcales 28221|Deltaproteobacteria F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD1_k127_813589_1 1242864.D187_004657 5.699e-90 309.0 COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,42SJI@68525|delta/epsilon subdivisions,2WPX2@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx DYD1_k127_813589_0 926569.ANT_16840 0.0 1067.0 COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD1_k127_813589_3 926569.ANT_22300 5.704e-14 80.0 COG3299@1|root,COG3299@2|Bacteria 2|Bacteria S Baseplate J-like protein - - 3.2.1.78 ko:K01218 ko00051,ko02024,map00051,map02024 - R01332 RC00467 ko00000,ko00001,ko01000 - GH26 - Baseplate_J,PA14,fn3 DYD1_k127_873276_1 926569.ANT_02800 1.597e-93 316.0 COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi 200795|Chloroflexi S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N DYD1_k127_873276_0 926569.ANT_02790 5.596e-183 593.0 COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi 200795|Chloroflexi M NTF2-like N-terminal transpeptidase domain - - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - MecA_N,PBP_dimer,Transpeptidase DYD1_k127_881282_6 215803.DB30_1144 5.596e-101 345.0 COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,42P3A@68525|delta/epsilon subdivisions,2WIJU@28221|Deltaproteobacteria,2YYR4@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde dehydrogenase family - - - ko:K04021 ko00620,ko01100,ko01120,map00620,map01100,map01120 - R00228 RC00004,RC01195 ko00000,ko00001 - - - Aldedh DYD1_k127_881282_23 215803.DB30_1142 2.449e-31 125.0 COG4576@1|root,COG4576@2|Bacteria,1RIK4@1224|Proteobacteria,4362N@68525|delta/epsilon subdivisions,2X9F2@28221|Deltaproteobacteria,2Z246@29|Myxococcales 28221|Deltaproteobacteria CQ Ethanolamine utilisation protein EutN/carboxysome - - - - - - - - - - - - EutN_CcmL DYD1_k127_881282_22 1499967.BAYZ01000012_gene2485 9.417e-35 143.0 COG4577@1|root,COG4577@2|Bacteria,2NRBW@2323|unclassified Bacteria 2|Bacteria CQ COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein - - - ko:K04027 - - - - ko00000 - - - BMC DYD1_k127_881282_7 63737.Npun_R1556 5.106e-89 297.0 COG4577@1|root,COG4577@2|Bacteria,1G0GA@1117|Cyanobacteria,1HJ6T@1161|Nostocales 1117|Cyanobacteria CQ PFAM BMC domain - - - - - - - - - - - - BMC DYD1_k127_881282_11 1191523.MROS_1910 1.086e-79 274.0 COG0274@1|root,COG0274@2|Bacteria 2|Bacteria F deoxyribose-phosphate aldolase activity deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.1.15,4.1.2.4,5.4.2.8,5.4.3.3 ko:K00852,ko:K01619,ko:K01840,ko:K01844 ko00030,ko00051,ko00310,ko00520,ko01100,ko01110,ko01130,map00030,map00051,map00310,map00520,map01100,map01110,map01130 M00114 R01051,R01066,R01818,R02750,R02852,R03275 RC00002,RC00017,RC00408,RC00436,RC00437,RC00719 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS00835,iYO844.BSU39420 DeoC,Lys-AminoMut_A DYD1_k127_881282_18 234267.Acid_2204 1.037e-51 199.0 COG0698@1|root,COG0698@2|Bacteria 2|Bacteria G galactose-6-phosphate isomerase activity upp - 2.4.2.9,5.3.1.6 ko:K00761,ko:K01808 ko00030,ko00051,ko00240,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00240,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R00966,R01056,R09030 RC00063,RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB,UPRTase DYD1_k127_881282_12 926550.CLDAP_32840 1.22e-75 262.0 COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi 200795|Chloroflexi K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA DYD1_k127_881282_19 926569.ANT_07910 1.901e-46 186.0 COG0845@1|root,COG0845@2|Bacteria,2G8US@200795|Chloroflexi 200795|Chloroflexi M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_881282_9 926569.ANT_07920 1.227e-83 293.0 COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi 200795|Chloroflexi P Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_881282_1 926569.ANT_07930 1.018e-148 482.0 COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi 200795|Chloroflexi V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_881282_10 1128421.JAGA01000003_gene3537 1.171e-82 288.0 COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria 2|Bacteria T Two component transcriptional regulator, winged helix family - - - - - - - - - - - - Response_reg,Trans_reg_C DYD1_k127_881282_5 1128421.JAGA01000003_gene3536 1.462e-109 373.0 COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria 2|Bacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K02484,ko:K07642 ko02020,map02020 M00450,M00645,M00646,M00648 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_881282_24 1484460.JSWG01000012_gene1574 2.341e-27 116.0 COG5580@1|root,COG5580@2|Bacteria,4PK53@976|Bacteroidetes,1I3SX@117743|Flavobacteriia 976|Bacteroidetes O Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD1_k127_881282_27 869213.JCM21142_41957 6.314e-13 78.0 COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,47PRX@768503|Cytophagia 976|Bacteroidetes S PFAM DUF218 domain - - - - - - - - - - - - DUF218 DYD1_k127_881282_25 263358.VAB18032_02490 4.997e-22 100.0 COG0748@1|root,COG0748@2|Bacteria,2I5PB@201174|Actinobacteria 201174|Actinobacteria P Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx DYD1_k127_881282_0 926569.ANT_01730 1.518e-161 519.0 COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - 2.4.1.250 ko:K15521 - - - - ko00000,ko01000 - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_881282_20 1382306.JNIM01000001_gene1923 2.841e-46 173.0 COG2606@1|root,COG2606@2|Bacteria,2G6MD@200795|Chloroflexi 200795|Chloroflexi S Aminoacyl-tRNA editing domain - - - - - - - - - - - - tRNA_edit DYD1_k127_881282_8 926569.ANT_19710 1.178e-85 287.0 COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi 200795|Chloroflexi F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK DYD1_k127_881282_15 42256.RradSPS_0129 1.43e-65 233.0 COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CQGA@84995|Rubrobacteria 84995|Rubrobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase DYD1_k127_881282_21 926569.ANT_19700 2.49e-45 179.0 COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi 200795|Chloroflexi S PFAM SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc DYD1_k127_881282_14 1122182.KB903837_gene3780 9.884e-67 238.0 COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,4DF2R@85008|Micromonosporales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_881282_3 357808.RoseRS_2859 2.623e-131 432.0 COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia 32061|Chloroflexia H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC - 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N DYD1_k127_881282_16 357808.RoseRS_2858 6.047e-59 224.0 COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi,37765@32061|Chloroflexia 32061|Chloroflexia M carboxylic acid catabolic process - - - - - - - - - - - - - DYD1_k127_881282_13 926569.ANT_17350 1.02e-69 248.0 COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi 200795|Chloroflexi M NmrA-like family - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - NAD_binding_10 DYD1_k127_881282_2 485916.Dtox_1182 6.156e-144 468.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae 186801|Clostridia I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_881282_4 926550.CLDAP_06710 4.1e-114 382.0 COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi 200795|Chloroflexi I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD1_k127_881282_17 926569.ANT_15100 3.149e-53 189.0 COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi 200795|Chloroflexi O Belongs to the thioredoxin family - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_900982_8 926569.ANT_24850 2.624e-07 57.0 COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi 200795|Chloroflexi Q PFAM amidohydrolase hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 DYD1_k127_900982_2 1121405.dsmv_3084 1.056e-69 252.0 COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria,2MHNH@213118|Desulfobacterales 28221|Deltaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_900982_5 926569.ANT_00160 2.343e-37 148.0 28U8H@1|root,2ZGE4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_900982_4 1121272.KB903249_gene2255 9.207e-46 171.0 COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales 201174|Actinobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase DYD1_k127_900982_3 926569.ANT_00140 5.301e-48 182.0 COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulator, Rrf2 family - - - - - - - - - - - - Rrf2 DYD1_k127_900982_0 926550.CLDAP_35420 2.469e-184 587.0 COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi 200795|Chloroflexi C Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_900982_1 926569.ANT_25170 3.636e-156 505.0 COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi 200795|Chloroflexi S Peptidase M16 domain protein - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_900982_6 926569.ANT_25160 5.805e-20 94.0 COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi 200795|Chloroflexi S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_902410_17 1128421.JAGA01000002_gene111 0.0002493 52.0 COG5401@1|root,COG5401@2|Bacteria 2|Bacteria T PFAM Sporulation and spore germination - - - - - - - - - - - - Germane,Gmad2 DYD1_k127_902410_12 863239.AFIZ01000032_gene1903 1.074e-11 70.0 COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,22M9W@1653|Corynebacteriaceae 201174|Actinobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_902410_5 926550.CLDAP_09500 1.563e-54 196.0 COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF664) - - - - - - - - - - - - DinB_2 DYD1_k127_902410_9 1121943.KB899994_gene966 6.948e-25 110.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MVYW@1224|Proteobacteria 1224|Proteobacteria C Cytochrome c oxidase subunit ctaC - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3 DYD1_k127_902410_3 402881.Plav_0832 1.722e-72 259.0 COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2V94H@28211|Alphaproteobacteria,1JQ4W@119043|Rhodobiaceae 28211|Alphaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD1_k127_902410_7 1121380.JNIW01000027_gene3117 1.398e-45 172.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus - - - - - - - - - - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5 DYD1_k127_902410_10 479433.Caci_8915 3.903e-18 98.0 2ES6T@1|root,33JRJ@2|Bacteria,2I9QF@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_902410_0 926569.ANT_11480 4.891e-143 464.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase yghO - - - - - - - - - - - Acetyltransf_1 DYD1_k127_902410_4 926569.ANT_22580 1.985e-66 261.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi 200795|Chloroflexi KLTU Protein tyrosine kinase - - - - - - - - - - - - PD40,Pkinase DYD1_k127_902410_1 926569.ANT_22580 9.31e-142 474.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi 200795|Chloroflexi KLTU Protein tyrosine kinase - - - - - - - - - - - - PD40,Pkinase DYD1_k127_902410_8 926569.ANT_30860 1.052e-40 159.0 COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi 200795|Chloroflexi I PFAM phospholipid glycerol acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_902410_16 880072.Desac_2179 2.453e-05 55.0 COG0468@1|root,COG0468@2|Bacteria 2|Bacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - - - - - - - - - - AAA_12,AAA_24,AAA_25,DUF4011 DYD1_k127_902410_15 880072.Desac_2172 3.915e-07 55.0 arCOG07300@1|root,2ZTGG@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_902410_14 1335760.ASTG01000017_gene3460 1.47e-09 71.0 2C1UQ@1|root,33VUD@2|Bacteria,1RM45@1224|Proteobacteria,2UBKR@28211|Alphaproteobacteria,2K9TG@204457|Sphingomonadales 204457|Sphingomonadales S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_902410_11 709797.CSIRO_2339 4.057e-18 98.0 COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,2TSZG@28211|Alphaproteobacteria,3JU5Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase MA20_15725 - - - - - - - - - - - PMT_2 DYD1_k127_902410_13 439235.Dalk_2449 1.113e-11 70.0 COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,42XJQ@68525|delta/epsilon subdivisions,2WSMN@28221|Deltaproteobacteria,2MP2F@213118|Desulfobacterales 28221|Deltaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - - DYD1_k127_902410_2 880072.Desac_2171 1.956e-132 455.0 COG0417@1|root,COG0417@2|Bacteria 2|Bacteria L DNA replication proofreading polB - 2.7.7.7 ko:K02336,ko:K06877 - - - - ko00000,ko01000,ko03400 - - - CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2 DYD1_k127_902410_6 1232410.KI421428_gene1209 5.491e-52 192.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,43TF2@69541|Desulfuromonadales 28221|Deltaproteobacteria S Inhibitor of apoptosis-promoting Bax1 ybhL - - ko:K06890,ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I DYD1_k127_912119_16 1379270.AUXF01000003_gene3469 4.178e-17 81.0 COG1376@1|root,COG1376@2|Bacteria,1ZUFC@142182|Gemmatimonadetes 142182|Gemmatimonadetes S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD DYD1_k127_912119_5 861299.J421_2858 2.137e-82 288.0 COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 DYD1_k127_912119_12 1173028.ANKO01000056_gene2185 7.49e-25 110.0 COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales 2|Bacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - ko:K03406,ko:K21009 ko02020,ko02025,ko02030,map02020,map02025,map02030 - - - ko00000,ko00001,ko02035 - - - GAF,GAF_2,HATPase_c,HisKA,MCPsignal,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_912119_14 1161401.ASJA01000027_gene48 4.951e-20 91.0 COG3360@1|root,COG3360@2|Bacteria,1PURU@1224|Proteobacteria,2V0YI@28211|Alphaproteobacteria,43YVT@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Dodecin - - - - - - - - - - - - Dodecin DYD1_k127_912119_7 518766.Rmar_0728 4.618e-62 221.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1FJ6B@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M Glycine zipper - - - - - - - - - - - - Gly-zipper_Omp,OmpA,PD40 DYD1_k127_912119_8 1254432.SCE1572_00420 2.169e-51 190.0 COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria,2YVDJ@29|Myxococcales 28221|Deltaproteobacteria C Iron/manganese superoxide dismutases, C-terminal domain sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N DYD1_k127_912119_21 1242864.D187_008547 0.0001401 51.0 COG0745@1|root,COG0745@2|Bacteria,1NQ8U@1224|Proteobacteria 1224|Proteobacteria KT Domain of unknown function (DUF4388) - - - - - - - - - - - - DUF4388,Response_reg DYD1_k127_912119_6 96561.Dole_0135 1.025e-76 284.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2X708@28221|Deltaproteobacteria,2MJ7A@213118|Desulfobacterales 28221|Deltaproteobacteria M Transglycosylase - - 2.4.1.129,3.4.16.4 ko:K05366,ko:K21464 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase DYD1_k127_912119_17 1121035.AUCH01000004_gene249 9.479e-17 83.0 COG2261@1|root,COG2261@2|Bacteria,1NE11@1224|Proteobacteria 1224|Proteobacteria S transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc DYD1_k127_912119_19 1121918.ARWE01000001_gene2193 3.097e-07 60.0 COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,42RMP@68525|delta/epsilon subdivisions,2X5PZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S bacterial OsmY and nodulation domain - - - - - - - - - - - - BON DYD1_k127_912119_15 1128421.JAGA01000002_gene1090 8.609e-20 94.0 2BZBR@1|root,32YH6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Transgly_assoc DYD1_k127_912119_3 237368.SCABRO_02350 2.011e-179 604.0 COG3852@1|root,COG3852@2|Bacteria,2J4Y6@203682|Planctomycetes 203682|Planctomycetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,PAS_9,Response_reg DYD1_k127_912119_2 1166018.FAES_0673 7.027e-188 602.0 COG0467@1|root,COG0467@2|Bacteria,4NKD2@976|Bacteroidetes,47MA6@768503|Cytophagia 976|Bacteroidetes T KaiC - - - ko:K08482 - - - - ko00000 - - - ATPase DYD1_k127_912119_10 386456.JQKN01000001_gene1698 8.739e-34 133.0 COG0526@1|root,arCOG07612@2157|Archaea,2Y43J@28890|Euryarchaeota 28890|Euryarchaeota O KaiB - - - ko:K08481 - - - - ko00000 - - - KaiB DYD1_k127_912119_11 1123242.JH636434_gene4661 4.642e-29 119.0 COG4251@1|root,COG4251@2|Bacteria 2|Bacteria T photoreceptor activity kaiB - - ko:K08481 - - - - ko00000 - - - HATPase_c,KaiB,PAS_4,dCache_1 DYD1_k127_912119_4 1173027.Mic7113_3984 3.679e-124 422.0 COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HA21@1150|Oscillatoriales 1117|Cyanobacteria T His Kinase A (phosphoacceptor) domain - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg DYD1_k127_912119_18 1123073.KB899241_gene2416 2.686e-13 81.0 2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,1SHR2@1236|Gammaproteobacteria,1X8SM@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD1_k127_912119_1 1380391.JIAS01000017_gene543 2.466e-193 629.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - Radical_SAM DYD1_k127_912119_9 1298863.AUEP01000009_gene133 2.149e-45 186.0 2AWU5@1|root,31NR9@2|Bacteria,2IQ6J@201174|Actinobacteria 201174|Actinobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 DYD1_k127_912119_13 452637.Oter_0944 1.375e-22 106.0 COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,3K87F@414999|Opitutae 414999|Opitutae S RNA recognition motif - - - - - - - - - - - - RRM_1 DYD1_k127_912119_0 404589.Anae109_4026 0.0 3975.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2YV3K@29|Myxococcales 28221|Deltaproteobacteria G Glycosyl hydrolase 36 superfamily, catalytic domain - - 2.4.1.20 ko:K00702,ko:K13688 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000,ko01003 - GH94,GT36,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase DYD1_k127_912119_20 1380354.JIAN01000008_gene3446 4.662e-07 57.0 COG1917@1|root,COG1917@2|Bacteria,2IQ74@201174|Actinobacteria 201174|Actinobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - DYD1_k127_960431_2 671143.DAMO_1037 3.471e-18 87.0 COG1135@1|root,COG1135@2|Bacteria 2|Bacteria P methionine transport - - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Fer4,NIL DYD1_k127_960431_1 1458357.BG58_33395 1.121e-41 159.0 COG1917@1|root,COG1917@2|Bacteria,1RH8X@1224|Proteobacteria,2VSGV@28216|Betaproteobacteria,1K8VS@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM Cupin 2 conserved barrel domain protein - - - - - - - - - - - - Cupin_2 DYD1_k127_960431_0 460265.Mnod_7641 6.572e-135 431.0 COG0702@1|root,COG0702@2|Bacteria,1MYVU@1224|Proteobacteria,2TTHA@28211|Alphaproteobacteria,1JUQ5@119045|Methylobacteriaceae 28211|Alphaproteobacteria GM epimerase - - - - - - - - - - - - NAD_binding_10,NmrA DYD1_k127_967045_2 926569.ANT_11730 8.26e-114 380.0 COG0416@1|root,COG0416@2|Bacteria,2G5Z8@200795|Chloroflexi 200795|Chloroflexi I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis DYD1_k127_967045_1 477974.Daud_0644 1.501e-127 437.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae 186801|Clostridia I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_967045_4 926569.ANT_11720 6.855e-11 72.0 2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - NERD DYD1_k127_967045_0 926569.ANT_20590 6.953e-154 492.0 COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi 200795|Chloroflexi S SPFH domain-Band 7 family - - - - - - - - - - - - Band_7_1,HTH_17,zinc_ribbon_2 DYD1_k127_967045_3 926569.ANT_20600 4.655e-51 188.0 arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - DYD1_k127_992820_1 266117.Rxyl_2946 4.159e-131 454.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria 84995|Rubrobacteria T Transcriptional regulator - - - - - - - - - - - - BTAD,Trans_reg_C DYD1_k127_992820_0 926569.ANT_04140 0.0 1282.0 COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi 200795|Chloroflexi O ATPase associated with various cellular activities, AAA_5 - - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD1_k127_992820_7 671143.DAMO_0416 8.413e-40 173.0 COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - CBS,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_992820_5 926569.ANT_31200 3.251e-55 224.0 COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA DYD1_k127_992820_2 338966.Ppro_2729 2.025e-93 343.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42T1Z@68525|delta/epsilon subdivisions,2WPPA@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - GAF,HAMP,HATPase_c,HisKA,PAS,PAS_2,PHY DYD1_k127_992820_4 1173026.Glo7428_2204 7.847e-63 220.0 COG0784@1|root,COG0784@2|Bacteria,1GQ4W@1117|Cyanobacteria 1117|Cyanobacteria T PFAM response regulator receiveR - - - - - - - - - - - - Response_reg DYD1_k127_992820_3 243231.GSU1656 1.231e-77 276.0 COG2199@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2204@2|Bacteria,1QVAY@1224|Proteobacteria,42TG1@68525|delta/epsilon subdivisions,2WVCZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Response receiver sensor diguanylate cyclase, PAS domain-containing - - - - - - - - - - - - GGDEF,PAS,PAS_4,Response_reg DYD1_k127_992820_8 1318628.MARLIPOL_02845 1.075e-30 142.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg DYD1_k127_992820_6 1210884.HG799462_gene9086 3.76e-51 209.0 COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes 203682|Planctomycetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_992820_9 1121428.DESHY_110386___1 3.873e-26 127.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_4 ## 3084 queries scanned ## Total time (seconds): 39.86393618583679 ## Rate: 77.36 q/s