## Sun Mar 16 03:00:07 2025
## emapper-2.1.9
## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD1_bin.33.fa -m mmseqs --itype genome -o DYD1_bin.33 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD1_bin.33 --cpu 8
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DYD1_k127_1025427_1	66429.JOFL01000017_gene405	4.551e-08	55.0	COG5515@1|root,COG5515@2|Bacteria,2GU6H@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1737)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1737
DYD1_k127_1025427_0	267608.RSc0451	6.919e-57	200.0	2BYAC@1|root,32R5Y@2|Bacteria,1NBTP@1224|Proteobacteria,2W2XI@28216|Betaproteobacteria,1KDKD@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1055011_2	397278.JOJN01000003_gene1765	3.546e-21	101.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4DUU0@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD1_k127_1055011_6	1459636.NTE_00702	6.961e-06	61.0	arCOG08777@1|root,arCOG08800@1|root,arCOG08777@2157|Archaea,arCOG08800@2157|Archaea	2157|Archaea	L	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1055011_5	1122138.AQUZ01000001_gene1708	6.15e-10	74.0	COG2133@1|root,COG3291@1|root,COG3507@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,2GJFY@201174|Actinobacteria,4DRVK@85009|Propionibacteriales	201174|Actinobacteria	G	Carbohydrate binding module (family 6)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,CBM_6,GSDH,PKD
DYD1_k127_1055011_1	287.DR97_4093	8.243e-90	312.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1YDXF@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
DYD1_k127_1055011_4	1122603.ATVI01000005_gene3254	5.743e-12	69.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1X7MG@135614|Xanthomonadales	135614|Xanthomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
DYD1_k127_1055011_0	1236689.MMALV_13960	1.188e-154	505.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,3F2II@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
DYD1_k127_1055011_3	1132509.C447_08368	1.263e-20	105.0	COG0614@1|root,arCOG04233@2157|Archaea,2XUJY@28890|Euryarchaeota,23TU0@183963|Halobacteria	183963|Halobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	btuF	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
DYD1_k127_1071632_0	1380390.JIAT01000009_gene1220	1.144e-49	188.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CP81@84995|Rubrobacteria	84995|Rubrobacteria	L	DbpA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DbpA,Helicase_C
DYD1_k127_1071632_1	593117.TGAM_1002	1.626e-17	92.0	COG5542@1|root,arCOG10055@2157|Archaea,2Y6AZ@28890|Euryarchaeota,243RZ@183968|Thermococci	183968|Thermococci	M	dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
DYD1_k127_1163376_0	234267.Acid_7630	5.75e-80	271.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
DYD1_k127_1204799_0	187272.Mlg_0261	2.181e-89	303.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales	135613|Chromatiales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
DYD1_k127_1217507_1	368407.Memar_0854	5.486e-15	76.0	COG2511@1|root,arCOG01719@2157|Archaea,2XT73@28890|Euryarchaeota,2N9BR@224756|Methanomicrobia	224756|Methanomicrobia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	-	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
DYD1_k127_1217507_0	1207063.P24_04355	1.607e-32	134.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,2JRPN@204441|Rhodospirillales	204441|Rhodospirillales	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
DYD1_k127_1302852_0	768670.Calni_2058	1.422e-159	517.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GF76@200930|Deferribacteres	200930|Deferribacteres	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DYD1_k127_148006_4	439235.Dalk_1316	5.122e-165	527.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42PFP@68525|delta/epsilon subdivisions,2WKYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_synthase
DYD1_k127_148006_28	1121286.AUMT01000005_gene3184	4.238e-68	237.0	COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1I2RN@117743|Flavobacteriia,3ZQV7@59732|Chryseobacterium	976|Bacteroidetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DYD1_k127_148006_18	1131269.AQVV01000034_gene2266	1.195e-93	317.0	COG0107@1|root,COG0107@2|Bacteria	2|Bacteria	E	imidazoleglycerol-phosphate synthase activity	hisF2	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DYD1_k127_148006_30	419610.Mext_3714	1.377e-66	241.0	COG1091@1|root,COG1091@2|Bacteria,1PEQX@1224|Proteobacteria,2U19I@28211|Alphaproteobacteria,1JXG3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
DYD1_k127_148006_10	314278.NB231_16878	1.153e-120	397.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1WXX0@135613|Chromatiales	135613|Chromatiales	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
DYD1_k127_148006_9	596151.DesfrDRAFT_2389	2.952e-131	431.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,42P5U@68525|delta/epsilon subdivisions,2WK5C@28221|Deltaproteobacteria,2MG4Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	UDP-N-acetylglucosamine 2-epimerase	wbjD	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DYD1_k127_148006_24	1489678.RDMS_08175	2.581e-79	282.0	COG0438@1|root,COG2148@1|root,COG0438@2|Bacteria,COG2148@2|Bacteria,1WIX1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf,Epimerase,Glyco_trans_4_4,Glycos_transf_1
DYD1_k127_148006_58	368407.Memar_0684	4.52e-13	81.0	arCOG01314@1|root,arCOG01314@2157|Archaea,2XVNC@28890|Euryarchaeota,2NB6C@224756|Methanomicrobia	224756|Methanomicrobia	L	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
DYD1_k127_148006_16	70601.3256777	9.368e-94	317.0	COG0714@1|root,arCOG00434@2157|Archaea,2XSZU@28890|Euryarchaeota,242ZG@183968|Thermococci	183968|Thermococci	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DYD1_k127_148006_64	662479.C440_05208	3.432e-09	69.0	arCOG02744@1|root,arCOG02744@2157|Archaea,2XV62@28890|Euryarchaeota,23TQQ@183963|Halobacteria	183963|Halobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DYD1_k127_148006_73	78345.BMERY_1188	4.689e-05	55.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4CZKW@85004|Bifidobacteriales	201174|Actinobacteria	DM	Psort location CytoplasmicMembrane, score	wcoI	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
DYD1_k127_148006_74	225849.swp_3120	5.243e-05	51.0	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria,2QCRS@267890|Shewanellaceae	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
DYD1_k127_148006_53	439481.Aboo_1330	3.286e-17	91.0	arCOG07412@1|root,arCOG07412@2157|Archaea,2Y0S5@28890|Euryarchaeota,3F2T8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_77	1033806.HTIA_2576	0.0004055	49.0	arCOG07235@1|root,arCOG07235@2157|Archaea,2XZXA@28890|Euryarchaeota,23XXN@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_61	933262.AXAM01000153_gene833	1.037e-11	68.0	COG2026@1|root,COG2026@2|Bacteria	933262.AXAM01000153_gene833|-	DJ	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_59	647113.Metok_1628	1.239e-12	70.0	arCOG05071@1|root,arCOG05071@2157|Archaea,2Y0VX@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF2683)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2683
DYD1_k127_148006_55	1227497.C491_06923	7.998e-15	80.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
DYD1_k127_148006_36	1094980.Mpsy_2836	1.088e-44	175.0	COG4002@1|root,arCOG00854@2157|Archaea,2XVHH@28890|Euryarchaeota,2NBJX@224756|Methanomicrobia	224756|Methanomicrobia	S	methyltransferase activity	mtxX	-	-	-	-	-	-	-	-	-	-	-	PTA_PTB
DYD1_k127_148006_71	1219084.AP014508_gene461	2.791e-05	57.0	COG1305@1|root,COG1305@2|Bacteria,2GC1R@200918|Thermotogae	200918|Thermotogae	E	transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
DYD1_k127_148006_15	673860.AciM339_0537	4.032e-106	364.0	COG0470@1|root,arCOG00470@2157|Archaea,2XT81@28890|Euryarchaeota,3F2FB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcL	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,Rad17
DYD1_k127_148006_37	383372.Rcas_2937	1.678e-43	169.0	COG0614@1|root,COG0614@2|Bacteria,2G8ZP@200795|Chloroflexi,375F3@32061|Chloroflexia	32061|Chloroflexia	P	PFAM periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
DYD1_k127_148006_32	195103.CPF_1408	1.333e-55	220.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,36E0Y@31979|Clostridiaceae	186801|Clostridia	L	helicase	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
DYD1_k127_148006_43	452637.Oter_2385	2.761e-28	121.0	COG1694@1|root,COG1694@2|Bacteria,46W6C@74201|Verrucomicrobia,3K875@414999|Opitutae	414999|Opitutae	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
DYD1_k127_148006_44	694430.Natoc_0820	9.594e-26	124.0	arCOG11394@1|root,arCOG11394@2157|Archaea,2XU8U@28890|Euryarchaeota,23UIW@183963|Halobacteria	183963|Halobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DYD1_k127_148006_67	33035.JPJF01000014_gene4788	2.468e-08	65.0	COG0863@1|root,COG0863@2|Bacteria,1TPR7@1239|Firmicutes,24A3P@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
DYD1_k127_148006_42	604354.TSIB_0198	2.019e-28	125.0	COG1992@1|root,arCOG00021@2157|Archaea,2XT4Y@28890|Euryarchaeota,243AG@183968|Thermococci	183968|Thermococci	H	Thiamine-phosphate synthase	-	-	-	ko:K22206	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,Terminase_5,ThiP_synth
DYD1_k127_148006_60	1197130.BAFM01000005_gene1075	7.159e-12	74.0	COG3398@1|root,arCOG02611@2157|Archaea,2XX30@28890|Euryarchaeota,23VMW@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
DYD1_k127_148006_45	439481.Aboo_1446	7.963e-25	121.0	COG0750@1|root,arCOG00609@2157|Archaea,2XT29@28890|Euryarchaeota,3F2WK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
DYD1_k127_148006_22	413816.BBJP01000017_gene1220	9.017e-82	292.0	COG1078@1|root,arCOG04430@2157|Archaea,2XUT7@28890|Euryarchaeota,23S02@183963|Halobacteria	183963|Halobacteria	S	COG1078 HD superfamily phosphohydrolases	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
DYD1_k127_148006_38	224324.aq_172	5.155e-38	153.0	COG2231@1|root,COG2231@2|Bacteria,2G41H@200783|Aquificae	200783|Aquificae	L	PFAM HhH-GPD family protein	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
DYD1_k127_148006_75	1094980.Mpsy_2661	0.0001036	50.0	arCOG06113@1|root,arCOG06113@2157|Archaea,2Y130@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_5	880073.Calab_3204	5.137e-156	515.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DYD1_k127_148006_8	1131266.ARWQ01000009_gene925	2.929e-131	429.0	COG0183@1|root,arCOG01278@2157|Archaea,41SCI@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD1_k127_148006_65	1131266.ARWQ01000009_gene924	1.312e-08	64.0	COG1545@1|root,arCOG01285@2157|Archaea,41SQK@651137|Thaumarchaeota	651137|Thaumarchaeota	V	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
DYD1_k127_148006_47	519442.Huta_1008	7.752e-21	101.0	arCOG10295@1|root,arCOG10295@2157|Archaea,2Y1V0@28890|Euryarchaeota	28890|Euryarchaeota	S	SatD family (SatD)	-	-	-	-	-	-	-	-	-	-	-	-	SatD
DYD1_k127_148006_52	1380390.JIAT01000011_gene2883	1.878e-17	96.0	COG0028@1|root,COG0515@1|root,COG1409@1|root,COG1749@1|root,COG2374@1|root,COG3291@1|root,COG3509@1|root,COG4733@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1409@2|Bacteria,COG1749@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,COG4733@2|Bacteria,2I2X3@201174|Actinobacteria,4CSIX@84995|Rubrobacteria	84995|Rubrobacteria	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,fn3
DYD1_k127_148006_17	795797.C497_02257	1.019e-93	334.0	COG2936@1|root,arCOG07590@2157|Archaea	2157|Archaea	S	acyl esterases	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DYD1_k127_148006_34	316278.SynRCC307_0339	6.131e-53	195.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1H0VR@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
DYD1_k127_148006_27	351160.RCIX288	8.9e-70	256.0	COG0044@1|root,arCOG00689@2157|Archaea,2XTQU@28890|Euryarchaeota,2N9BT@224756|Methanomicrobia	224756|Methanomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DYD1_k127_148006_49	262724.TT_C0186	1.118e-19	99.0	COG2426@1|root,COG2426@2|Bacteria,1WJT8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	small multi-drug export	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
DYD1_k127_148006_7	673860.AciM339_0479	8.237e-146	486.0	COG0343@1|root,COG1370@1|root,arCOG00989@2157|Archaea,arCOG00991@2157|Archaea,2XTFH@28890|Euryarchaeota,3F2F8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PUA,TGT,TGT_C1,TGT_C2
DYD1_k127_148006_23	1232410.KI421420_gene3181	2.743e-81	283.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,43TYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Quinolinate synthetase A protein	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
DYD1_k127_148006_33	269797.Mbar_A1866	2.352e-55	204.0	COG1712@1|root,arCOG00254@2157|Archaea,2XUNA@28890|Euryarchaeota,2NBJI@224756|Methanomicrobia	224756|Methanomicrobia	F	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
DYD1_k127_148006_31	1869.MB27_38885	2.468e-57	211.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4DAMZ@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
DYD1_k127_148006_72	348780.NP_1128A	4.474e-05	56.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWHT@28890|Euryarchaeota,23V64@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	gntR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_5,MarR_2
DYD1_k127_148006_14	1121087.AUCK01000003_gene1223	6.148e-108	365.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_148006_69	1132441.KI519454_gene2119	8.391e-07	57.0	COG1695@1|root,COG1695@2|Bacteria,2GMKD@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
DYD1_k127_148006_6	342949.PNA2_0013	2.534e-151	491.0	COG0160@1|root,arCOG00915@2157|Archaea,2Y83J@28890|Euryarchaeota,2431R@183968|Thermococci	183968|Thermococci	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DYD1_k127_148006_56	1206720.BAFQ01000010_gene273	1.041e-14	85.0	2CFT8@1|root,2ZBMC@2|Bacteria,2IFWU@201174|Actinobacteria,4FV12@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_62	926569.ANT_03070	3.782e-11	76.0	COG5295@1|root,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_41	1123405.AUMM01000034_gene1692	1.002e-28	129.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
DYD1_k127_148006_76	743718.Isova_1016	0.0003135	53.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DYD1_k127_148006_2	439481.Aboo_0072	4.115e-299	934.0	COG0480@1|root,arCOG01559@2157|Archaea,2XUMQ@28890|Euryarchaeota,3F2GN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DYD1_k127_148006_29	1236689.MMALV_03250	1.352e-66	234.0	COG0049@1|root,arCOG04254@2157|Archaea,2XTDC@28890|Euryarchaeota,3F2JI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DYD1_k127_148006_26	673860.AciM339_0981	2.018e-70	244.0	COG0048@1|root,arCOG04255@2157|Archaea,2XX4A@28890|Euryarchaeota,3F2K0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DYD1_k127_148006_21	1380387.JADM01000004_gene3027	1.909e-82	297.0	COG4188@1|root,COG4188@2|Bacteria,1Q4K6@1224|Proteobacteria,1S7GC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_40	1192034.CAP_8828	1.688e-31	139.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
DYD1_k127_148006_46	1236689.MMALV_16400	3.318e-21	100.0	COG0195@1|root,arCOG01760@2157|Archaea,2Y6CH@28890|Euryarchaeota,3F2TQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5
DYD1_k127_148006_50	1041930.Mtc_2148	2.914e-19	90.0	COG1911@1|root,arCOG01752@2157|Archaea,2Y0CU@28890|Euryarchaeota,2NA2A@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM ribosomal protein L7Ae L30e S12e Gadd45	rpl30e	-	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
DYD1_k127_148006_13	589924.Ferp_0760	1.068e-110	377.0	COG0086@1|root,arCOG04256@2157|Archaea,2XTJ6@28890|Euryarchaeota,245Q4@183980|Archaeoglobi	183980|Archaeoglobi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	-	2.7.7.6	ko:K03042	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_5
DYD1_k127_148006_1	693661.Arcve_1352	0.0	1055.0	COG0086@1|root,arCOG04257@2157|Archaea,2XTBZ@28890|Euryarchaeota,245UU@183980|Archaeoglobi	183980|Archaeoglobi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DYD1_k127_148006_0	1236689.MMALV_16440	0.0	1347.0	COG0085@1|root,arCOG01762@2157|Archaea,2XU1X@28890|Euryarchaeota,3F2FW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03044,ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DYD1_k127_148006_57	679926.Mpet_1738	7.489e-14	79.0	COG2012@1|root,arCOG04258@2157|Archaea,2Y0EY@28890|Euryarchaeota,2NA20@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoH	-	2.7.7.6	ko:K03053	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb5_C
DYD1_k127_148006_68	1502852.FG94_02016	1.112e-07	61.0	2DKFZ@1|root,309D6@2|Bacteria,1QZK6@1224|Proteobacteria,2WHMG@28216|Betaproteobacteria,476NY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
DYD1_k127_148006_19	660470.Theba_2574	8.026e-84	292.0	COG1916@1|root,COG1916@2|Bacteria	2|Bacteria	-	-	traB	-	-	-	-	-	-	-	-	-	-	-	TraB
DYD1_k127_148006_39	521011.Mpal_1987	7.45e-32	134.0	COG1994@1|root,arCOG00614@2157|Archaea,2XX7B@28890|Euryarchaeota	28890|Euryarchaeota	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_35	1343739.PAP_05865	6.365e-50	189.0	COG1951@1|root,arCOG04407@2157|Archaea,2XUQI@28890|Euryarchaeota,242SI@183968|Thermococci	183968|Thermococci	C	Fumarate hydratase	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
DYD1_k127_148006_51	519442.Huta_1865	1.245e-17	95.0	arCOG00381@1|root,arCOG07561@1|root,arCOG00382@2157|Archaea,arCOG07561@2157|Archaea,2XV3J@28890|Euryarchaeota,23UWG@183963|Halobacteria	183963|Halobacteria	K	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
DYD1_k127_148006_20	1078083.HMPREF1208_00686	2.994e-83	287.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,4HAA4@91061|Bacilli,4GXHX@90964|Staphylococcaceae	91061|Bacilli	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
DYD1_k127_148006_12	1382315.JPOI01000001_gene2905	3.596e-116	398.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,4HA8C@91061|Bacilli,1WEEY@129337|Geobacillus	91061|Bacilli	C	Pyruvate:ferredoxin oxidoreductase core domain II	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DYD1_k127_148006_48	1227457.C451_04928	5.683e-20	93.0	COG3388@1|root,arCOG01345@2157|Archaea,2XXVY@28890|Euryarchaeota,23W4Z@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_148006_66	1086011.HJ01_01706	1.861e-08	65.0	COG1266@1|root,COG1266@2|Bacteria,4NTIG@976|Bacteroidetes,1HXSY@117743|Flavobacteriia,2NVHK@237|Flavobacterium	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DYD1_k127_148006_54	192952.MM_2617	1.782e-16	86.0	COG1325@1|root,arCOG01042@2157|Archaea,2Y01Q@28890|Euryarchaeota,2NA08@224756|Methanomicrobia	224756|Methanomicrobia	J	RNA binding	-	-	-	ko:K07581	-	-	-	-	ko00000	-	-	-	RNA_binding
DYD1_k127_148006_3	1054217.TALC_00658	7.883e-238	749.0	COG1245@1|root,arCOG00187@2157|Archaea,2XSZE@28890|Euryarchaeota,241KJ@183967|Thermoplasmata	183967|Thermoplasmata	E	Possible Fer4-like domain in RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
DYD1_k127_148006_70	670487.Ocepr_0182	8.779e-06	54.0	COG0589@1|root,COG0589@2|Bacteria,1WIFP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD1_k127_148006_11	572546.Arcpr_0357	2.401e-117	392.0	COG1899@1|root,arCOG04142@2157|Archaea,2XSTD@28890|Euryarchaeota,2461M@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DYD1_k127_148006_63	1457250.BBMO01000001_gene717	3.405e-09	70.0	COG1520@1|root,COG3291@1|root,arCOG02546@2157|Archaea,arCOG02556@2157|Archaea,2Y7Q9@28890|Euryarchaeota,240XC@183963|Halobacteria	183963|Halobacteria	C	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
DYD1_k127_148006_25	1349785.BAUG01000008_gene655	1.257e-70	244.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,4NDZ9@976|Bacteroidetes,1HX7P@117743|Flavobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
DYD1_k127_1511385_0	1108045.GORHZ_109_00020	9.496e-29	128.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
DYD1_k127_1540375_0	1499967.BAYZ01000014_gene6394	3.247e-46	169.0	COG1216@1|root,COG1216@2|Bacteria,2NPQN@2323|unclassified Bacteria	2|Bacteria	S	Glycosyltransferase like family 2	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD1_k127_1560119_0	882086.SacxiDRAFT_0851	8.921e-08	65.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4E1CS@85010|Pseudonocardiales	201174|Actinobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,ThuA
DYD1_k127_1700903_0	1218084.BBJK01000064_gene4831	5.48e-13	68.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2VH89@28216|Betaproteobacteria,1K485@119060|Burkholderiaceae	28216|Betaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
DYD1_k127_1734474_8	1121938.AUDY01000009_gene2092	5.485e-99	337.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,3NDAF@45667|Halobacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_1734474_27	933115.GPDM_15019	2.963e-10	73.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,26E03@186818|Planococcaceae	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_1734474_5	1449126.JQKL01000021_gene63	2.523e-105	355.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,268FV@186813|unclassified Clostridiales	186801|Clostridia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_1734474_18	386456.JQKN01000002_gene2681	3.021e-35	150.0	COG1041@1|root,arCOG00047@2157|Archaea,2XTD6@28890|Euryarchaeota,23NJD@183925|Methanobacteria	183925|Methanobacteria	L	methylase	-	-	2.1.1.213	ko:K07446	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP,UPF0020
DYD1_k127_1734474_10	1094980.Mpsy_2010	6.51e-83	291.0	COG1602@1|root,arCOG04269@2157|Archaea,2XTEQ@28890|Euryarchaeota,2N9FP@224756|Methanomicrobia	224756|Methanomicrobia	S	Archaeal Nre, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
DYD1_k127_1734474_12	1047013.AQSP01000115_gene356	1.62e-57	220.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
DYD1_k127_1734474_32	443218.AS9A_2374	2.126e-07	62.0	COG4923@1|root,COG4923@2|Bacteria,2IJP8@201174|Actinobacteria,238UV@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
DYD1_k127_1734474_16	316056.RPC_1680	2.363e-43	172.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,2TVK9@28211|Alphaproteobacteria,3JV4K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Conserved hypothetical protein 698	yeiH	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
DYD1_k127_1734474_21	349161.Dred_2675	7.373e-27	118.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia,25ZZ6@186807|Peptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
DYD1_k127_1734474_14	1157637.KB892090_gene6240	1.314e-54	208.0	COG3845@1|root,COG3845@2|Bacteria,2I2Y2@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, ATP-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
DYD1_k127_1734474_28	485916.Dtox_1966	1.354e-09	68.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,2616E@186807|Peptococcaceae	186801|Clostridia	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
DYD1_k127_1734474_26	643648.Slip_0328	1.909e-13	80.0	28RTZ@1|root,30ITU@2|Bacteria,1UV8V@1239|Firmicutes,25AK0@186801|Clostridia,42KRA@68298|Syntrophomonadaceae	186801|Clostridia	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
DYD1_k127_1734474_23	1348583.ATLH01000017_gene2671	9.173e-16	92.0	COG3291@1|root,COG3291@2|Bacteria,4PHZA@976|Bacteroidetes,1IGQC@117743|Flavobacteriia,1F9WN@104264|Cellulophaga	976|Bacteroidetes	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DYD1_k127_1734474_29	1120971.AUCA01000031_gene163	2.728e-08	65.0	COG1657@1|root,COG1657@2|Bacteria,1UWRC@1239|Firmicutes,4I2G9@91061|Bacilli,27A6V@186823|Alicyclobacillaceae	91061|Bacilli	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
DYD1_k127_1734474_34	1120948.KB903217_gene1367	1.854e-06	59.0	2C75R@1|root,2ZCK5@2|Bacteria,2IBVD@201174|Actinobacteria,4E8JR@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1734474_0	1236689.MMALV_00640	9.686e-130	437.0	COG1031@1|root,arCOG01359@2157|Archaea,2XSVQ@28890|Euryarchaeota,3F2GV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	HHH,HHH_3,Radical_SAM
DYD1_k127_1734474_11	693661.Arcve_0260	1.476e-57	216.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUT0@28890|Euryarchaeota,24644@183980|Archaeoglobi	28890|Euryarchaeota	E	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_1734474_35	1353531.AZNX01000005_gene3276	5.336e-06	58.0	COG1277@1|root,COG1277@2|Bacteria,1R5P4@1224|Proteobacteria	1224|Proteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DYD1_k127_1734474_13	1150600.ADIARSV_3202	8.721e-55	195.0	COG4270@1|root,COG4270@2|Bacteria,4NQEX@976|Bacteroidetes,1ITAE@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
DYD1_k127_1734474_6	477974.Daud_1091	4.48e-103	353.0	COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,247Z2@186801|Clostridia,2609W@186807|Peptococcaceae	186801|Clostridia	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
DYD1_k127_1734474_17	263358.VAB18032_06040	1.312e-41	164.0	COG1427@1|root,COG1427@2|Bacteria,2GJGY@201174|Actinobacteria,4D8EF@85008|Micromonosporales	201174|Actinobacteria	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DYD1_k127_1734474_7	1121472.AQWN01000010_gene468	3.411e-101	346.0	COG1060@1|root,COG1060@2|Bacteria,1TQNG@1239|Firmicutes,24AHE@186801|Clostridia,260QC@186807|Peptococcaceae	186801|Clostridia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DYD1_k127_1734474_30	316067.Geob_3465	7.671e-08	66.0	COG2373@1|root,COG2931@1|root,COG4257@1|root,COG5029@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG4257@2|Bacteria,COG5029@2|Bacteria	2|Bacteria	O	Prenyltransferase	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	A2M,An_peroxidase,CHRD,CarboxypepD_reg,Prenyltrans
DYD1_k127_1734474_9	673860.AciM339_0552	1.846e-89	307.0	COG0258@1|root,arCOG04050@2157|Archaea,2XTJD@28890|Euryarchaeota,3F2GZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
DYD1_k127_1734474_24	1210046.B277_00985	1.278e-15	90.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4FEGZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_1734474_4	673860.AciM339_0566	1.172e-113	377.0	COG0731@1|root,arCOG04174@2157|Archaea,2XSTF@28890|Euryarchaeota,3F2ET@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
DYD1_k127_1734474_22	414996.IL38_22970	1.118e-16	93.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,409Z0@622450|Actinopolysporales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_1734474_1	351160.RCIX568	2.248e-125	423.0	COG0018@1|root,arCOG00487@2157|Archaea,2XTWP@28890|Euryarchaeota,2N9C5@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DYD1_k127_1734474_25	693661.Arcve_0149	2.388e-15	89.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_1734474_3	673860.AciM339_1206	5.245e-118	394.0	COG1503@1|root,arCOG01742@2157|Archaea,2XSV5@28890|Euryarchaeota,3F2IF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
DYD1_k127_1734474_19	523841.HFX_1947	4.994e-33	139.0	COG0528@1|root,arCOG00858@2157|Archaea,2XT3U@28890|Euryarchaeota,23TA7@183963|Halobacteria	183963|Halobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DYD1_k127_1734474_31	224325.AF_0872	1.273e-07	55.0	COG4068@1|root,arCOG04390@2157|Archaea	2157|Archaea	S	Uncharacterized protein containing a Zn-ribbon (DUF2116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
DYD1_k127_1734474_15	665571.STHERM_c01250	9.569e-48	187.0	COG2309@1|root,COG2309@2|Bacteria,2J605@203691|Spirochaetes	203691|Spirochaetes	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
DYD1_k127_1734474_37	1236689.MMALV_00420	4.446e-05	49.0	arCOG05368@1|root,arCOG05368@2157|Archaea,2Y1EG@28890|Euryarchaeota,3F2W6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1734474_2	1218173.BALCAV_0200165	8.917e-124	414.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,1ZC51@1386|Bacillus	91061|Bacilli	J	asparaginyl-tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DYD1_k127_1734474_20	439235.Dalk_3827	1.196e-32	139.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GFO_IDH_MocA
DYD1_k127_1734474_33	1283299.AUKG01000002_gene3738	9.203e-07	57.0	28WQB@1|root,2ZIQ0@2|Bacteria,2INA2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1749774_0	1403819.BATR01000195_gene6595	3.496e-20	104.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
DYD1_k127_1776169_4	1033737.CAEV01000001_gene2353	3.567e-08	66.0	2EYIP@1|root,33RSF@2|Bacteria,1VSNU@1239|Firmicutes,24YEW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1776169_0	1463921.JODF01000004_gene2484	8.701e-36	153.0	2EJC1@1|root,33D35@2|Bacteria,2GJ5Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1776169_3	1202768.JROF01000026_gene3598	8.935e-10	72.0	COG5410@1|root,arCOG09550@2157|Archaea	2157|Archaea	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
DYD1_k127_1776169_5	485913.Krac_9164	2.345e-07	62.0	arCOG05626@1|root,32V4D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1776169_6	416348.Hlac_3041	8.864e-06	48.0	arCOG08100@1|root,arCOG08100@2157|Archaea,2Y185@28890|Euryarchaeota,23YDJ@183963|Halobacteria	183963|Halobacteria	S	transposon-encoded protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2080
DYD1_k127_1776169_1	460265.Mnod_3568	7.293e-15	87.0	2DWJ8@1|root,340MS@2|Bacteria,1PZQA@1224|Proteobacteria,2UKRY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HNH_3
DYD1_k127_1776169_2	1266925.JHVX01000006_gene2038	6.8e-11	68.0	2DEAB@1|root,2ZM5M@2|Bacteria,1PWSJ@1224|Proteobacteria,2WCB8@28216|Betaproteobacteria,374JS@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1790172_20	485913.Krac_3213	6.996e-47	174.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DYD1_k127_1790172_6	1094980.Mpsy_2726	4.588e-97	323.0	COG0638@1|root,arCOG00971@2157|Archaea,2XUKA@28890|Euryarchaeota,2N98W@224756|Methanomicrobia	224756|Methanomicrobia	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmA	GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
DYD1_k127_1790172_12	673860.AciM339_0866	1.069e-71	252.0	COG1500@1|root,arCOG04187@2157|Archaea,2XTNH@28890|Euryarchaeota,3F2JN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
DYD1_k127_1790172_13	1236689.MMALV_02990	1.125e-71	249.0	COG1097@1|root,arCOG00678@2157|Archaea,2XWEN@28890|Euryarchaeota,3F2JY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,KH_1,KH_6,S1
DYD1_k127_1790172_7	304371.MCP_2627	1.588e-86	292.0	COG0689@1|root,arCOG01575@2157|Archaea,2XVHI@28890|Euryarchaeota,2N95P@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	-	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
DYD1_k127_1790172_10	1236689.MMALV_02970	3.034e-75	260.0	COG2123@1|root,arCOG01574@2157|Archaea,2XWTK@28890|Euryarchaeota,3F2JS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
DYD1_k127_1790172_17	443143.GM18_2625	3.604e-51	193.0	2B0GJ@1|root,31SU3@2|Bacteria,1RI4W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1790172_25	1117319.PSPO_20376	9.272e-35	152.0	COG3343@1|root,COG5183@1|root,COG3343@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,2Q202@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	AK	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
DYD1_k127_1790172_22	314345.SPV1_06084	3.586e-41	160.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria	1224|Proteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
DYD1_k127_1790172_28	604354.TSIB_1345	2.979e-24	105.0	COG1997@1|root,arCOG04208@2157|Archaea,2XYWD@28890|Euryarchaeota,244K8@183968|Thermococci	183968|Thermococci	J	binds to the 23S rRNA	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
DYD1_k127_1790172_35	192952.MM_2626	1.258e-11	67.0	COG1996@1|root,arCOG04341@2157|Archaea,2XZUD@28890|Euryarchaeota,2NA5N@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoP	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	DNA_RNApol_7kD
DYD1_k127_1790172_34	439481.Aboo_0090	4.545e-13	73.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75P@28890|Euryarchaeota,3F3FQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
DYD1_k127_1790172_9	868131.MSWAN_2046	2.095e-75	266.0	COG0281@1|root,arCOG01331@2157|Archaea,2XTRZ@28890|Euryarchaeota,23PHT@183925|Methanobacteria	183925|Methanobacteria	O	Belongs to the peptidase M48B family	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
DYD1_k127_1790172_23	1041930.Mtc_0662	8.546e-40	156.0	COG0468@1|root,arCOG00417@2157|Archaea,2XTI2@28890|Euryarchaeota,2N9KC@224756|Methanomicrobia	224756|Methanomicrobia	L	Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange	radB	-	-	ko:K04484	-	-	-	-	ko00000,ko03400	-	-	-	Rad51
DYD1_k127_1790172_37	593750.Metfor_1996	2.982e-09	68.0	COG3398@1|root,arCOG02611@2157|Archaea,2XV4M@28890|Euryarchaeota,2NB4N@224756|Methanomicrobia	224756|Methanomicrobia	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_1790172_18	1236689.MMALV_15550	1.809e-49	186.0	COG0061@1|root,COG0483@1|root,arCOG01348@2157|Archaea,arCOG01349@2157|Archaea,2XTP6@28890|Euryarchaeota	28890|Euryarchaeota	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Inositol_P,NAD_kinase
DYD1_k127_1790172_14	439481.Aboo_0078	5.721e-57	209.0	COG0061@1|root,arCOG01348@2157|Archaea,2XTP6@28890|Euryarchaeota,3F32I@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Inositol_P,NAD_kinase
DYD1_k127_1790172_26	673860.AciM339_0974	1.37e-27	121.0	COG1310@1|root,arCOG01139@2157|Archaea,2XWKU@28890|Euryarchaeota,3F2SY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
DYD1_k127_1790172_4	439481.Aboo_1385	6.552e-123	421.0	COG0433@1|root,arCOG00280@2157|Archaea,2Y7MA@28890|Euryarchaeota,3F30Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
DYD1_k127_1790172_21	797303.Natpe_1497	3.315e-45	188.0	COG1033@1|root,arCOG02174@2157|Archaea,2XT5A@28890|Euryarchaeota,23SV0@183963|Halobacteria	183963|Halobacteria	L	exporters of the RND superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
DYD1_k127_1790172_29	1236689.MMALV_01400	1.508e-22	104.0	COG1849@1|root,arCOG01224@2157|Archaea,2XYS0@28890|Euryarchaeota,3F2SZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF357)	-	-	-	ko:K09728	-	-	-	-	ko00000	-	-	-	DUF357
DYD1_k127_1790172_19	673860.AciM339_1009	6.227e-48	180.0	COG0164@1|root,arCOG04121@2157|Archaea,2XWYC@28890|Euryarchaeota,3F2N8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DYD1_k127_1790172_24	1120970.AUBZ01000022_gene1313	1.029e-37	153.0	COG2050@1|root,COG2050@2|Bacteria,1RKGI@1224|Proteobacteria,1S59D@1236|Gammaproteobacteria,46AZU@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
DYD1_k127_1790172_5	871968.DESME_03270	3.991e-109	364.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2611H@186807|Peptococcaceae	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_1790172_11	1121430.JMLG01000008_gene1513	2.965e-74	259.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD1_k127_1790172_31	1227497.C491_09454	3.05e-17	86.0	COG1487@1|root,arCOG02219@2157|Archaea,2XX7I@28890|Euryarchaeota,23VMN@183963|Halobacteria	183963|Halobacteria	V	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
DYD1_k127_1790172_38	694430.Natoc_0959	3.367e-08	59.0	arCOG08146@1|root,arCOG08146@2157|Archaea	2157|Archaea	S	Putative antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	VAPB_antitox
DYD1_k127_1790172_32	484770.UFO1_2956	2.569e-16	85.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes	909932|Negativicutes	I	glutaconyl-CoA decarboxylase subunit gamma	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
DYD1_k127_1790172_1	649638.Trad_1116	5.037e-148	485.0	COG0439@1|root,COG0439@2|Bacteria,1WHZX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	acetyl-CoA carboxylase biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DYD1_k127_1790172_40	706434.HMPREF9429_01580	0.0003525	44.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4H2BA@909932|Negativicutes	909932|Negativicutes	I	methylmalonyl-CoA decarboxylase alpha subunit	mmdA	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
DYD1_k127_1790172_0	523841.HFX_2478	4.584e-231	726.0	COG4799@1|root,arCOG02705@2157|Archaea,2XSVM@28890|Euryarchaeota,23T6H@183963|Halobacteria	183963|Halobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB2	GO:0003674,GO:0003824,GO:0004658,GO:0016421,GO:0016874,GO:0016885	2.1.3.15,6.4.1.2,6.4.1.3	ko:K19312	ko00280,ko00630,ko00640,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01120,map01130,map01200	M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DYD1_k127_1790172_15	439481.Aboo_1119	1.661e-54	200.0	COG1339@1|root,arCOG01904@2157|Archaea,2XTFW@28890|Euryarchaeota,3F2NZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)	ribK	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase,HTH_20,HTH_24,HTH_Crp_2
DYD1_k127_1790172_16	69014.TK0060	1.409e-52	191.0	COG1303@1|root,arCOG01857@2157|Archaea,2XV35@28890|Euryarchaeota,242JJ@183968|Thermococci	183968|Thermococci	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	-	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
DYD1_k127_1790172_30	1227457.C451_12617	1.937e-19	97.0	COG1675@1|root,arCOG04270@2157|Archaea,2XSWK@28890|Euryarchaeota,23SHC@183963|Halobacteria	183963|Halobacteria	K	Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes	tfe	-	-	ko:K03136	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIE_alpha
DYD1_k127_1790172_8	673860.AciM339_0524	4.674e-77	268.0	COG0463@1|root,arCOG01385@2157|Archaea,2XUEP@28890|Euryarchaeota,3F30S@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	aglI	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD1_k127_1790172_36	1293047.CBMA010000041_gene2569	3.412e-11	76.0	COG2244@1|root,arCOG02209@2157|Archaea,2XVVS@28890|Euryarchaeota,23UCY@183963|Halobacteria	183963|Halobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
DYD1_k127_1790172_27	644282.Deba_1008	4.923e-26	121.0	COG0438@1|root,COG5010@1|root,COG0438@2|Bacteria,COG5010@2|Bacteria,1PZAF@1224|Proteobacteria,435UK@68525|delta/epsilon subdivisions,2WWWY@28221|Deltaproteobacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	2.7.11.1	ko:K14949	ko05152,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	DUF3868,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,TPR_8
DYD1_k127_1790172_33	1379698.RBG1_1C00001G0994	3.464e-14	82.0	COG0500@1|root,COG2226@2|Bacteria,2NRJH@2323|unclassified Bacteria	2|Bacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
DYD1_k127_1790172_2	521011.Mpal_0345	4.96e-125	411.0	COG0381@1|root,arCOG01392@2157|Archaea,2XU0B@28890|Euryarchaeota,2N97W@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DYD1_k127_1790172_3	519442.Huta_1063	6.316e-125	414.0	COG0677@1|root,arCOG00252@2157|Archaea,2XUJT@28890|Euryarchaeota,23U0F@183963|Halobacteria	183963|Halobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DYD1_k127_1790172_39	32057.KB217478_gene6650	1.077e-05	50.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria	1117|Cyanobacteria	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DYD1_k127_1814739_12	4432.XP_010278283.1	1.505e-10	72.0	COG0170@1|root,KOG4453@2759|Eukaryota,37MAD@33090|Viridiplantae,3GB6V@35493|Streptophyta	35493|Streptophyta	I	Phytol kinase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006775,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009507,GO:0009536,GO:0009987,GO:0010189,GO:0010276,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0042360,GO:0042362,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617	2.7.1.182	ko:K18678	-	-	R10659	RC00002,RC00017	ko00000,ko01000	-	-	-	-
DYD1_k127_1814739_2	1054217.TALC_00051	2.878e-47	177.0	COG0558@1|root,arCOG00670@2157|Archaea,2XWJ0@28890|Euryarchaeota,241RQ@183967|Thermoplasmata	183967|Thermoplasmata	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
DYD1_k127_1814739_6	368407.Memar_1903	1.731e-21	102.0	COG1936@1|root,arCOG01038@2157|Archaea,2XX2A@28890|Euryarchaeota,2N9V1@224756|Methanomicrobia	224756|Methanomicrobia	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
DYD1_k127_1814739_0	439481.Aboo_0061	1.71e-145	475.0	COG0112@1|root,arCOG00070@2157|Archaea,2XU0H@28890|Euryarchaeota,3F2G1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DYD1_k127_1814739_11	593750.Metfor_1916	1.655e-11	77.0	COG3398@1|root,arCOG02611@2157|Archaea	2157|Archaea	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_1814739_4	1123501.KB902284_gene2261	2.966e-40	158.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	dapH	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DYD1_k127_1814739_7	1123226.KB899279_gene2388	1.185e-19	93.0	COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,26YKY@186822|Paenibacillaceae	91061|Bacilli	S	Thiol-disulfide oxidoreductase DCC	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
DYD1_k127_1814739_3	272844.PAB1235	2.055e-45	171.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,243RS@183968|Thermococci	183968|Thermococci	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DYD1_k127_1814739_10	1122221.JHVI01000001_gene1901	5.642e-12	70.0	COG0640@1|root,COG0640@2|Bacteria,1WKQ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
DYD1_k127_1814739_1	439481.Aboo_0655	2.142e-145	479.0	COG0533@1|root,arCOG01183@2157|Archaea,arCOG01185@2157|Archaea,2XT07@28890|Euryarchaeota,3F2H7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	LT	Protein kinase domain	kae1	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234,2.7.11.1	ko:K08851,ko:K15904	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko01001,ko03016	-	-	-	Kdo,Peptidase_M22,Pkinase,RIO1
DYD1_k127_1814739_14	269799.Gmet_3473	0.0007342	50.0	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WKXB@28221|Deltaproteobacteria,43W1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE,T2SSE_N
DYD1_k127_1814739_8	1294265.JCM21738_1461	4.927e-17	94.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,1ZE6M@1386|Bacillus	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_1814739_9	339670.Bamb_4142	2.852e-14	78.0	COG3794@1|root,COG3794@2|Bacteria,1NKZ5@1224|Proteobacteria,2VW1T@28216|Betaproteobacteria,1K8BA@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
DYD1_k127_1814739_5	543913.D521_1163	1.381e-31	130.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2VRTS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
DYD1_k127_1814739_13	208439.AJAP_16180	1.644e-10	74.0	COG4409@1|root,COG4409@2|Bacteria,2ICIA@201174|Actinobacteria,4EBQC@85010|Pseudonocardiales	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DYD1_k127_1823220_0	926550.CLDAP_12100	3.068e-14	84.0	COG3385@1|root,COG3385@2|Bacteria,2G7UE@200795|Chloroflexi	200795|Chloroflexi	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1836729_1	261292.Nit79A3_0169	4.544e-16	88.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,2VVPQ@28216|Betaproteobacteria,37394@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
DYD1_k127_1836729_0	1283300.ATXB01000001_gene79	1.835e-25	111.0	COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria,1XFI4@135618|Methylococcales	135618|Methylococcales	NU	TIGRFAM Pilus modification type IV, PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
DYD1_k127_1847773_0	765912.Thimo_0565	1.412e-119	397.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1S15T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Pfam Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
DYD1_k127_1954276_1	1246995.AFR_08180	3.981e-96	326.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DAC8@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
DYD1_k127_1954276_2	368407.Memar_0658	4.547e-63	226.0	COG0842@1|root,arCOG01463@2157|Archaea,2XXQI@28890|Euryarchaeota,2N9MG@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
DYD1_k127_1954276_0	192952.MM_1416	2.426e-101	345.0	COG0150@1|root,arCOG00639@2157|Archaea,2XTBA@28890|Euryarchaeota,2N9C4@224756|Methanomicrobia	224756|Methanomicrobia	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DYD1_k127_1955149_0	483219.LILAB_25990	3.866e-109	368.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria,43BG6@68525|delta/epsilon subdivisions,2X6UH@28221|Deltaproteobacteria,2Z0N1@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_1955149_1	886293.Sinac_7245	1.855e-43	165.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria	2|Bacteria	L	transposition	iS4C	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
DYD1_k127_2013834_0	1007096.BAGW01000025_gene1457	9.411e-10	72.0	COG3451@1|root,COG3451@2|Bacteria,1TQGE@1239|Firmicutes,24ACY@186801|Clostridia,2N88J@216572|Oscillospiraceae	186801|Clostridia	U	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
DYD1_k127_2030933_7	1198114.AciX9_3354	2.549e-18	93.0	COG0340@1|root,COG0340@2|Bacteria,3Y4PB@57723|Acidobacteria,2JMQP@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
DYD1_k127_2030933_0	604331.AUHY01000062_gene1501	1.899e-164	540.0	COG1166@1|root,COG1166@2|Bacteria,1WJ0J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
DYD1_k127_2030933_3	358681.BBR47_11890	7.344e-66	240.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_2030933_2	1089551.KE386572_gene3138	4.53e-82	286.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,4BQ5Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
DYD1_k127_2030933_8	748247.AZKH_p0302	7.536e-16	87.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VNUR@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Lysine exporter protein (Lyse ygga)	leuE_1	-	-	ko:K11250	-	-	-	-	ko00000,ko02000	2.A.76.1.5	-	-	LysE
DYD1_k127_2030933_1	69014.TK0550	2.338e-159	515.0	COG0008@1|root,arCOG00402@2157|Archaea,2XSUM@28890|Euryarchaeota,242RZ@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DYD1_k127_2030933_4	313606.M23134_06681	1.211e-60	221.0	COG0431@1|root,COG0431@2|Bacteria,4NN31@976|Bacteroidetes,47SD0@768503|Cytophagia	976|Bacteroidetes	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DYD1_k127_2030933_5	1236689.MMALV_00540	5.611e-40	166.0	COG0565@1|root,arCOG01018@2157|Archaea,2XUIY@28890|Euryarchaeota,3F2NC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	TIGRFAM RNA methyltransferase, TrmH family, group 1	trmH	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
DYD1_k127_2030933_9	634497.HAH_1433	1.001e-05	55.0	arCOG04605@1|root,arCOG04605@2157|Archaea,2XXBX@28890|Euryarchaeota,23VP1@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
DYD1_k127_2030933_6	673860.AciM339_0628	5.188e-21	94.0	arCOG05238@1|root,arCOG05238@2157|Archaea,2Y0YG@28890|Euryarchaeota,3F3EA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2045624_23	1459636.NTE_00702	4.3e-05	57.0	arCOG08777@1|root,arCOG08800@1|root,arCOG08777@2157|Archaea,arCOG08800@2157|Archaea	2157|Archaea	L	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2045624_24	67352.JODS01000029_gene2512	0.000443	52.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,TPR_8,Trans_reg_C
DYD1_k127_2045624_1	673860.AciM339_1081	1.409e-138	455.0	COG0180@1|root,arCOG01887@2157|Archaea,2XSVC@28890|Euryarchaeota,3F2N6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	tRNA synthetases class I (W and Y)	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A1374	tRNA-synt_1b
DYD1_k127_2045624_7	1365176.N186_01065	1.674e-55	212.0	COG1530@1|root,arCOG00321@2157|Archaea,2XQ2D@28889|Crenarchaeota	28889|Crenarchaeota	L	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DYD1_k127_2045624_15	1313172.YM304_10900	9.631e-18	97.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DYD1_k127_2045624_16	1410622.JNKY01000018_gene704	1.137e-16	92.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,27IE6@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DYD1_k127_2045624_13	1894.JOER01000018_gene4913	9.999e-27	123.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
DYD1_k127_2045624_3	373994.Riv7116_5693	8.676e-97	346.0	COG1132@1|root,COG1132@2|Bacteria,1G02Q@1117|Cyanobacteria,1HJ4J@1161|Nostocales	1117|Cyanobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DYD1_k127_2045624_20	1227488.C477_08488	2.644e-09	70.0	COG5276@1|root,arCOG02565@2157|Archaea,2XV6J@28890|Euryarchaeota,23SNQ@183963|Halobacteria	183963|Halobacteria	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_2045624_2	342949.PNA2_0723	9.841e-129	422.0	COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota,243KU@183968|Thermococci	183968|Thermococci	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
DYD1_k127_2045624_10	693661.Arcve_1281	5.205e-46	175.0	COG1779@1|root,arCOG04265@2157|Archaea,2XWNA@28890|Euryarchaeota,2465V@183980|Archaeoglobi	183980|Archaeoglobi	S	Zinc finger domain	-	-	-	ko:K06874	-	-	-	-	ko00000	-	-	-	zf-ZPR1
DYD1_k127_2045624_8	304371.MCP_1018	1.733e-53	201.0	COG3390@1|root,arCOG02258@2157|Archaea,2XT3R@28890|Euryarchaeota,2N9P2@224756|Methanomicrobia	224756|Methanomicrobia	S	protein conserved in archaea	-	-	-	ko:K09746	-	-	-	-	ko00000	-	-	-	-
DYD1_k127_2045624_5	1236689.MMALV_01600	2.13e-65	243.0	COG1599@1|root,arCOG01510@2157|Archaea,2XTGJ@28890|Euryarchaeota,3F2KP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	rpa1	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
DYD1_k127_2045624_9	399550.Smar_0060	3.084e-49	192.0	COG0668@1|root,arCOG01568@2157|Archaea,2XSS1@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
DYD1_k127_2045624_19	1094980.Mpsy_1328	4.629e-12	68.0	COG1552@1|root,arCOG04049@2157|Archaea,2Y177@28890|Euryarchaeota,2NB9F@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the eukaryotic ribosomal protein eL40 family	rpl40e	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L40e
DYD1_k127_2045624_18	1123319.AUBE01000005_gene64	3.338e-16	93.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_2045624_12	673860.AciM339_0463	2.155e-35	144.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,3F3BI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
DYD1_k127_2045624_14	673860.AciM339_1185	2.804e-19	93.0	COG0727@1|root,arCOG02579@2157|Archaea,2Y1J3@28890|Euryarchaeota	28890|Euryarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DYD1_k127_2045624_22	69014.TK1580	1.351e-05	53.0	COG0727@1|root,arCOG02579@2157|Archaea,2Y268@28890|Euryarchaeota,24416@183968|Thermococci	183968|Thermococci	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DYD1_k127_2045624_11	1054217.TALC_01127	4.354e-38	153.0	COG0717@1|root,arCOG04048@2157|Archaea,2Y6CE@28890|Euryarchaeota,241VF@183967|Thermoplasmata	183967|Thermoplasmata	F	dUTPase	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
DYD1_k127_2045624_17	456442.Mboo_0375	1.17e-16	94.0	COG3398@1|root,arCOG02611@2157|Archaea,2XV4M@28890|Euryarchaeota,2NB4N@224756|Methanomicrobia	224756|Methanomicrobia	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_2045624_21	74545.EU96_0062	2.788e-08	62.0	COG0817@1|root,COG0817@2|Bacteria,1G62E@1117|Cyanobacteria,1MME2@1212|Prochloraceae	1117|Cyanobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DYD1_k127_2045624_4	477974.Daud_0439	4.629e-67	239.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia,262MF@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_2045624_0	1472716.KBK24_0118610	3.292e-156	507.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,1K0QI@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
DYD1_k127_2045624_6	589924.Ferp_0234	2.323e-57	221.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2478R@183980|Archaeoglobi	28890|Euryarchaeota	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
DYD1_k127_2051615_0	1122604.JONR01000018_gene1060	8.184e-05	52.0	2DHCH@1|root,2ZZ8B@2|Bacteria,1PNFC@1224|Proteobacteria,1SQ5Y@1236|Gammaproteobacteria,1XAKG@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2100698_5	1288494.EBAPG3_23550	1.664e-07	63.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VU4X@28216|Betaproteobacteria,372W6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
DYD1_k127_2100698_1	1051632.TPY_1657	1.61e-124	416.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DYD1_k127_2100698_2	706587.Desti_1300	1.336e-112	377.0	COG0003@1|root,COG0071@1|root,COG0003@2|Bacteria,COG0071@2|Bacteria,1MUTX@1224|Proteobacteria,42P0N@68525|delta/epsilon subdivisions,2WKQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
DYD1_k127_2100698_3	1254432.SCE1572_07250	1.133e-19	97.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42W4B@68525|delta/epsilon subdivisions,2WP0P@28221|Deltaproteobacteria,2YVPV@29|Myxococcales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
DYD1_k127_2100698_4	62928.azo1585	3.238e-15	83.0	2DT7R@1|root,33J2W@2|Bacteria,1NQ33@1224|Proteobacteria,2VXQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2100698_0	42256.RradSPS_0746	1.064e-155	505.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CP6D@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DYD1_k127_213570_9	3218.PP1S46_300V6.1	6.734e-80	279.0	COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta	35493|Streptophyta	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DYD1_k127_213570_24	886293.Sinac_2076	8.03e-36	143.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DYD1_k127_213570_18	1453503.AU05_02075	1.837e-45	172.0	COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,1S480@1236|Gammaproteobacteria,1YG26@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
DYD1_k127_213570_2	797209.ZOD2009_04062	1.067e-180	582.0	COG0644@1|root,COG2440@1|root,arCOG00570@2157|Archaea,arCOG01984@2157|Archaea,2XV3Q@28890|Euryarchaeota,23UIF@183963|Halobacteria	183963|Halobacteria	C	COG0644 Dehydrogenases (flavoproteins)	ydiS	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3,FAD_oxidored,NAD_binding_8
DYD1_k127_213570_5	1455608.JDTH01000002_gene680	2.248e-123	406.0	COG2025@1|root,arCOG00448@2157|Archaea,2XUUG@28890|Euryarchaeota,23S2C@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
DYD1_k127_213570_8	797209.ZOD2009_04072	1.036e-83	286.0	COG2086@1|root,arCOG00446@2157|Archaea,2XTB8@28890|Euryarchaeota,23TTZ@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein, beta subunit	etfB2	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DYD1_k127_213570_3	861299.J421_1944	3.79e-148	487.0	COG0659@1|root,COG0659@2|Bacteria,1ZTYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
DYD1_k127_213570_11	253839.SSNG_00482	1.324e-63	230.0	COG3409@1|root,COG3770@1|root,COG3409@2|Bacteria,COG3770@2|Bacteria	2|Bacteria	M	serine-type endopeptidase activity	pdcA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M74
DYD1_k127_213570_0	316274.Haur_4673	1.598e-247	785.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi,3752D@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
DYD1_k127_213570_19	1168065.DOK_12797	2.051e-40	174.0	COG2304@1|root,COG4547@1|root,COG2304@2|Bacteria,COG4547@2|Bacteria,1RFDH@1224|Proteobacteria,1S0SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF1194,Prenyltrans
DYD1_k127_213570_28	253839.SSNG_03928	5.476e-06	57.0	COG2936@1|root,COG2936@2|Bacteria,2I1ZG@201174|Actinobacteria	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
DYD1_k127_213570_25	309801.trd_A0172	1.459e-12	74.0	COG0640@1|root,COG0640@2|Bacteria,2G9T1@200795|Chloroflexi,27ZA0@189775|Thermomicrobia	189775|Thermomicrobia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
DYD1_k127_213570_7	649638.Trad_2090	4.009e-106	358.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DYD1_k127_213570_16	673860.AciM339_0768	7.38e-53	194.0	COG1618@1|root,arCOG01034@2157|Archaea,2XX6U@28890|Euryarchaeota,3F2MF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
DYD1_k127_213570_12	69014.TK0970	8.929e-62	227.0	COG1867@1|root,arCOG01219@2157|Archaea,2XTUF@28890|Euryarchaeota,243GQ@183968|Thermococci	183968|Thermococci	J	Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups	trm1	GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
DYD1_k127_213570_20	272844.PAB1676	8.919e-39	160.0	COG0083@1|root,arCOG01027@2157|Archaea,2XUDU@28890|Euryarchaeota,243D9@183968|Thermococci	183968|Thermococci	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DYD1_k127_213570_4	523845.AQXV01000038_gene1117	1.145e-123	411.0	COG0498@1|root,arCOG01434@2157|Archaea,2XT84@28890|Euryarchaeota,23QKS@183939|Methanococci	183939|Methanococci	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD1_k127_213570_27	679926.Mpet_1243	2.359e-08	65.0	COG2061@1|root,arCOG04396@2157|Archaea,2XWMD@28890|Euryarchaeota,2N9PF@224756|Methanomicrobia	224756|Methanomicrobia	E	amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_213570_10	521011.Mpal_1993	5.869e-66	238.0	COG0460@1|root,arCOG01351@2157|Archaea,2XSWF@28890|Euryarchaeota,2N91A@224756|Methanomicrobia	224756|Methanomicrobia	E	homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
DYD1_k127_213570_15	85643.Tmz1t_1735	1.815e-53	197.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,2KW2K@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
DYD1_k127_213570_22	1071085.KK033114_gene156	1.794e-37	154.0	COG1637@1|root,arCOG01304@2157|Archaea,2XUC8@28890|Euryarchaeota,23S9C@183963|Halobacteria	183963|Halobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
DYD1_k127_213570_14	1121468.AUBR01000016_gene2299	4.22e-55	208.0	COG1565@1|root,COG1565@2|Bacteria,1V2II@1239|Firmicutes,24GK7@186801|Clostridia,42I8X@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
DYD1_k127_213570_6	644281.MFS40622_0391	3.787e-117	388.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,23QKG@183939|Methanococci	183939|Methanococci	S	TIGRFAM Small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
DYD1_k127_213570_23	634498.mru_0494	3.134e-37	155.0	COG0301@1|root,arCOG00038@2157|Archaea,2XUHM@28890|Euryarchaeota,23NP8@183925|Methanobacteria	183925|Methanobacteria	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
DYD1_k127_213570_21	1261545.MBE-HAL_1798	1.587e-38	158.0	COG1893@1|root,arCOG04139@2157|Archaea,2XTBD@28890|Euryarchaeota,23T98@183963|Halobacteria	183963|Halobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DYD1_k127_213570_17	1120973.AQXL01000134_gene1529	4.937e-51	188.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,2789X@186823|Alicyclobacillaceae	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DYD1_k127_213570_13	1121472.AQWN01000010_gene469	1.92e-59	220.0	COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,2486B@186801|Clostridia,25ZZE@186807|Peptococcaceae	186801|Clostridia	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DYD1_k127_213570_1	639282.DEFDS_1642	1.429e-188	601.0	COG0043@1|root,COG0043@2|Bacteria,2GF8C@200930|Deferribacteres	200930|Deferribacteres	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DYD1_k127_2179397_0	1097668.BYI23_E003070	2.837e-153	494.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,1K69S@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
DYD1_k127_2210401_6	797302.Halru_1910	4.342e-12	77.0	COG3398@1|root,arCOG02611@2157|Archaea,2XV4M@28890|Euryarchaeota,23V38@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD1_k127_2210401_1	357808.RoseRS_2289	1.248e-50	192.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,375B5@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DYD1_k127_2210401_0	324925.Ppha_1082	3.787e-77	262.0	COG0450@1|root,COG0450@2|Bacteria,1FE5C@1090|Chlorobi	1090|Chlorobi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
DYD1_k127_2210401_5	1120972.AUMH01000015_gene1345	2.141e-20	99.0	COG0824@1|root,COG0824@2|Bacteria,1V6GS@1239|Firmicutes,4HJ05@91061|Bacilli,278KI@186823|Alicyclobacillaceae	91061|Bacilli	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
DYD1_k127_2210401_4	304371.MCP_1864	1.703e-26	112.0	COG1733@1|root,arCOG01057@2157|Archaea,2XYND@28890|Euryarchaeota,2N9WD@224756|Methanomicrobia	224756|Methanomicrobia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_2210401_2	273116.14324278	5.192e-39	153.0	COG2095@1|root,arCOG01997@2157|Archaea,2XZEI@28890|Euryarchaeota,2426E@183967|Thermoplasmata	183967|Thermoplasmata	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
DYD1_k127_2210401_3	1545915.JROG01000004_gene2010	9.155e-39	157.0	COG4219@1|root,COG4219@2|Bacteria,1R3YH@1224|Proteobacteria,2U67Y@28211|Alphaproteobacteria,2K1JQ@204457|Sphingomonadales	204457|Sphingomonadales	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
DYD1_k127_2244683_2	595537.Varpa_3132	2.001e-71	258.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2VNYR@28216|Betaproteobacteria,4AJ6B@80864|Comamonadaceae	28216|Betaproteobacteria	P	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DYD1_k127_2244683_0	673860.AciM339_1121	2.014e-184	593.0	COG5253@1|root,arCOG04169@2157|Archaea,2XT9A@28890|Euryarchaeota,3F2F6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
DYD1_k127_2244683_15	1236689.MMALV_14040	8.485e-21	97.0	COG0200@1|root,arCOG00779@2157|Archaea,2XWM3@28890|Euryarchaeota,3F2U3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein L15	rpl15	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
DYD1_k127_2244683_9	323259.Mhun_2232	2.571e-44	166.0	COG1841@1|root,arCOG04086@2157|Archaea,2XWGP@28890|Euryarchaeota,2N9JA@224756|Methanomicrobia	224756|Methanomicrobia	J	TIGRFAM ribosomal protein L30P	rpl30	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
DYD1_k127_2244683_1	1236689.MMALV_14060	6.322e-79	272.0	COG0098@1|root,arCOG04087@2157|Archaea,2XUQU@28890|Euryarchaeota,3F2HF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S12 plays an important role in translational accuracy	rps5	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DYD1_k127_2244683_8	673860.AciM339_1117	2.42e-45	169.0	COG0256@1|root,arCOG04088@2157|Archaea,2XTWT@28890|Euryarchaeota,3F2QM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rpl18	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18_c,Ribosomal_L5e
DYD1_k127_2244683_10	1236689.MMALV_14080	6.356e-43	161.0	COG2147@1|root,arCOG04089@2157|Archaea,2XWU1@28890|Euryarchaeota,3F2Q2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl19e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
DYD1_k127_2244683_11	1236689.MMALV_14090	1.951e-38	148.0	COG1717@1|root,arCOG00781@2157|Archaea,2XSZ4@28890|Euryarchaeota,3F2PV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL32 family	rpl32e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L32e
DYD1_k127_2244683_5	529709.PYCH_01540	1.646e-54	197.0	COG0097@1|root,arCOG04090@2157|Archaea,2XTIS@28890|Euryarchaeota,243D5@183968|Thermococci	183968|Thermococci	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DYD1_k127_2244683_7	589924.Ferp_1151	1.277e-48	176.0	COG0096@1|root,arCOG04091@2157|Archaea,2XWMU@28890|Euryarchaeota,2466J@183980|Archaeoglobi	183980|Archaeoglobi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
DYD1_k127_2244683_16	1236689.MMALV_14120	2.155e-17	84.0	COG0199@1|root,arCOG00782@2157|Archaea,2Y68V@28890|Euryarchaeota,3F2V3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S14	rps14	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DYD1_k127_2244683_6	439481.Aboo_1508	3.123e-50	183.0	COG0094@1|root,arCOG04092@2157|Archaea,2XTRN@28890|Euryarchaeota,3F2KJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DYD1_k127_2244683_3	634498.mru_0864	1.056e-62	223.0	COG1471@1|root,arCOG04093@2157|Archaea,2XT03@28890|Euryarchaeota,23NT9@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the eukaryotic ribosomal protein eS4 family	rps4e	-	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
DYD1_k127_2244683_14	419665.Maeo_1395	1.2e-26	116.0	COG0198@1|root,arCOG04094@2157|Archaea,2XXV4@28890|Euryarchaeota,23QWH@183939|Methanococci	183939|Methanococci	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl24	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,Ribosomal_L26
DYD1_k127_2244683_4	673860.AciM339_1108	1.606e-59	209.0	COG0093@1|root,arCOG04095@2157|Archaea,2XWM6@28890|Euryarchaeota,3F2NF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DYD1_k127_2244683_13	693661.Arcve_0976	2.059e-30	123.0	COG0186@1|root,arCOG04096@2157|Archaea,2XYPE@28890|Euryarchaeota,24740@183980|Archaeoglobi	183980|Archaeoglobi	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DYD1_k127_2244683_18	765177.Desmu_1171	3.151e-09	61.0	COG1588@1|root,arCOG00784@2157|Archaea,2XR9D@28889|Crenarchaeota	28889|Crenarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	-	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
DYD1_k127_2244683_12	1054217.TALC_01327	1.802e-36	141.0	COG0023@1|root,arCOG04223@2157|Archaea,2XXW5@28890|Euryarchaeota,241TJ@183967|Thermoplasmata	183967|Thermoplasmata	J	posttranscriptional regulation of gene expression	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DYD1_k127_2244683_17	1236689.MMALV_14190	1.066e-15	78.0	COG0255@1|root,arCOG00785@2157|Archaea,2Y1DQ@28890|Euryarchaeota,3F2VT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal L29 protein	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DYD1_k127_2253963_0	391612.CY0110_01969	9.44e-09	67.0	COG3039@1|root,COG3039@2|Bacteria,1G3YX@1117|Cyanobacteria,3KJ5Y@43988|Cyanothece	1117|Cyanobacteria	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
DYD1_k127_225449_0	314230.DSM3645_21729	7.735e-71	247.0	29STU@1|root,30DZV@2|Bacteria,2IZET@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2323005_0	392499.Swit_3353	5.135e-05	49.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,1MY4G@1224|Proteobacteria,2U1X0@28211|Alphaproteobacteria,2KABH@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DYD1_k127_2372005_0	269482.Bcep1808_6250	4.685e-105	349.0	COG3293@1|root,COG3293@2|Bacteria,1REUV@1224|Proteobacteria,2VREC@28216|Betaproteobacteria,1K6P0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
DYD1_k127_2558150_0	644966.Tmar_0264	3.981e-32	130.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,24CUE@186801|Clostridia	186801|Clostridia	E	PFAM L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
DYD1_k127_2558150_1	391613.RTM1035_15817	1.272e-23	108.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,46P8W@74030|Roseovarius	28211|Alphaproteobacteria	S	SOS response associated peptidase (SRAP)	MA20_42060	-	-	-	-	-	-	-	-	-	-	-	SRAP
DYD1_k127_2581545_1	1463920.JOGB01000009_gene744	1.54e-48	184.0	COG0697@1|root,COG0697@2|Bacteria,2I9UQ@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_2581545_0	1089550.ATTH01000001_gene2290	1.312e-56	208.0	COG0120@1|root,COG0120@2|Bacteria,4NMB9@976|Bacteroidetes,1FJ6N@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
DYD1_k127_2588761_1	573065.Astex_0426	1.949e-05	49.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
DYD1_k127_2588761_0	631454.N177_3432	1.924e-84	281.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,1JNCW@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
DYD1_k127_2603919_0	379066.GAU_2993	4.067e-99	336.0	COG1408@1|root,COG1408@2|Bacteria,1ZV9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DYD1_k127_2603919_5	439481.Aboo_0790	3.939e-55	207.0	COG1938@1|root,arCOG00347@2157|Archaea,2XT93@28890|Euryarchaeota,3F2T7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
DYD1_k127_2603919_2	263820.PTO0734	2.479e-73	263.0	COG0492@1|root,arCOG01296@2157|Archaea,2XTJW@28890|Euryarchaeota,2424P@183967|Thermoplasmata	183967|Thermoplasmata	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD1_k127_2603919_9	673860.AciM339_1484	8.078e-37	149.0	COG1497@1|root,arCOG04399@2157|Archaea,2XU16@28890|Euryarchaeota,3F397@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Regulatory protein Crp	-	-	-	ko:K07730	-	-	-	-	ko00000,ko03000	-	-	-	HTH_24,MarR_2
DYD1_k127_2603919_3	273075.Ta0947	6.48e-67	240.0	COG1250@1|root,arCOG00250@2157|Archaea,2XTMV@28890|Euryarchaeota	28890|Euryarchaeota	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DYD1_k127_2603919_4	880073.Calab_0535	3.353e-60	222.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD1_k127_2603919_1	867845.KI911784_gene1118	5.75e-98	336.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,374SC@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_2603919_11	350688.Clos_0092	2.48e-29	128.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfB1	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DYD1_k127_2603919_7	875454.BAEW01000015_gene1519	1.562e-39	161.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,22G83@1570339|Peptoniphilaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha
DYD1_k127_2603919_12	134676.ACPL_3289	9.652e-14	81.0	COG1011@1|root,COG1011@2|Bacteria,2GNSS@201174|Actinobacteria,4DF7T@85008|Micromonosporales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	3.1.3.102,3.1.3.104	ko:K07025,ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
DYD1_k127_2603919_10	1445613.JALM01000070_gene6536	1.046e-30	131.0	COG1024@1|root,COG1024@2|Bacteria,2IEXB@201174|Actinobacteria,4E3W4@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA3_1	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DYD1_k127_2603919_6	370438.PTH_1767	2.339e-51	197.0	COG2025@1|root,COG2025@2|Bacteria,1V2AY@1239|Firmicutes,24FT1@186801|Clostridia,264WV@186807|Peptococcaceae	186801|Clostridia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DYD1_k127_2603919_8	1123250.KB908380_gene839	4.825e-37	151.0	COG2086@1|root,COG2086@2|Bacteria,1W75F@1239|Firmicutes,4H8AB@909932|Negativicutes	909932|Negativicutes	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF
DYD1_k127_2603919_13	1197130.BAFM01000002_gene464	4.618e-07	53.0	COG4023@1|root,arCOG02957@2157|Archaea,2Y024@28890|Euryarchaeota,23XMD@183963|Halobacteria	183963|Halobacteria	U	Involved in protein export. The function of the beta subunit is	secG	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
DYD1_k127_2651907_0	118166.JH976537_gene3690	1.938e-59	221.0	COG3385@1|root,2ZA2Q@2|Bacteria,1G4UP@1117|Cyanobacteria	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
DYD1_k127_2663945_4	456442.Mboo_1903	4.137e-41	174.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,2NAP1@224756|Methanomicrobia	224756|Methanomicrobia	N	Type II secretion system (T2SS), protein F	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DYD1_k127_2663945_3	1094980.Mpsy_0840	4.354e-50	189.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,2NAGM@224756|Methanomicrobia	224756|Methanomicrobia	N	Type II secretion system (T2SS), protein F	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DYD1_k127_2663945_0	439481.Aboo_0009	3.635e-160	543.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,3F2TI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II/IV secretion system protein	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DYD1_k127_2663945_5	797210.Halxa_2562	0.0009509	49.0	arCOG03926@1|root,arCOG03926@2157|Archaea,2Y02V@28890|Euryarchaeota,23XWR@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2663945_1	187272.Mlg_1586	1.49e-97	331.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1WXEN@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
DYD1_k127_2663945_2	1254432.SCE1572_10010	1.25e-81	280.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YV62@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DYD1_k127_2670611_0	1123508.JH636453_gene5800	6.661e-05	57.0	COG3391@1|root,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DYD1_k127_2710339_0	43179.ENSSTOP00000017611	9.297e-11	68.0	COG5640@1|root,KOG3627@2759|Eukaryota,39UMG@33154|Opisthokonta,3BKNJ@33208|Metazoa,3D4C0@33213|Bilateria,483K9@7711|Chordata,49357@7742|Vertebrata,3J1IG@40674|Mammalia,35DYE@314146|Euarchontoglires,4PVDX@9989|Rodentia	33208|Metazoa	O	complement activation, alternative pathway	CFD	GO:0000323,GO:0001775,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002521,GO:0002573,GO:0002576,GO:0002682,GO:0002684,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006508,GO:0006509,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006909,GO:0006928,GO:0006950,GO:0006952,GO:0006955,GO:0006956,GO:0006957,GO:0006959,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007275,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009987,GO:0012505,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016787,GO:0017171,GO:0019538,GO:0019899,GO:0023052,GO:0030097,GO:0030099,GO:0030100,GO:0030141,GO:0030154,GO:0031091,GO:0031093,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032502,GO:0032879,GO:0032940,GO:0033619,GO:0034330,GO:0034331,GO:0034774,GO:0035578,GO:0036230,GO:0040011,GO:0042119,GO:0042582,GO:0043085,GO:0043087,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043547,GO:0043954,GO:0044093,GO:0044238,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044853,GO:0045055,GO:0045087,GO:0045121,GO:0045123,GO:0045216,GO:0045217,GO:0045321,GO:0045806,GO:0046903,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050764,GO:0050765,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050900,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051336,GO:0051345,GO:0051674,GO:0051716,GO:0060205,GO:0060627,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0072376,GO:0072672,GO:0097028,GO:0097029,GO:0097529,GO:0097530,GO:0097708,GO:0098589,GO:0098590,GO:0098657,GO:0098805,GO:0098857,GO:0099503,GO:0101002,GO:0140096,GO:1901564,GO:1904813,GO:1990266	3.4.21.46,3.4.21.76	ko:K01334,ko:K01350	ko04610,ko05150,map04610,map05150	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Trypsin
DYD1_k127_2726128_1	1041147.AUFB01000051_gene4048	5.272e-32	128.0	COG3415@1|root,COG3415@2|Bacteria,1RJ69@1224|Proteobacteria,2UB2N@28211|Alphaproteobacteria,4BG9W@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	'Paired box' domain	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_32,HTH_Tnp_IS630,PAX
DYD1_k127_2726128_0	1117943.SFHH103_02919	5.376e-108	351.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,4BC2J@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase and inactivated	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
DYD1_k127_2744635_8	670487.Ocepr_1014	3.229e-71	252.0	COG0077@1|root,COG0077@2|Bacteria,1WIGR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
DYD1_k127_2744635_16	589924.Ferp_0234	4.495e-48	195.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2478R@183980|Archaeoglobi	28890|Euryarchaeota	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
DYD1_k127_2744635_26	572546.Arcpr_0273	8.873e-08	66.0	COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,245SZ@183980|Archaeoglobi	183980|Archaeoglobi	L	DNA polymerase	-	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
DYD1_k127_2744635_17	69395.JQLZ01000002_gene1093	1.692e-45	173.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,2KG98@204458|Caulobacterales	204458|Caulobacterales	J	Endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
DYD1_k127_2744635_15	1121920.AUAU01000012_gene2693	3.655e-50	182.0	COG2050@1|root,COG2050@2|Bacteria,3Y558@57723|Acidobacteria	57723|Acidobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
DYD1_k127_2744635_3	264732.Moth_0737	2.532e-80	287.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,42EX4@68295|Thermoanaerobacterales	186801|Clostridia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DYD1_k127_2744635_7	1123399.AQVE01000005_gene943	2.951e-71	250.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,45ZW8@72273|Thiotrichales	72273|Thiotrichales	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DYD1_k127_2744635_2	1121472.AQWN01000007_gene1144	1.235e-85	306.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DYD1_k127_2744635_13	1380394.JADL01000005_gene5496	4.698e-54	204.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TQSZ@28211|Alphaproteobacteria,2JVTW@204441|Rhodospirillales	204441|Rhodospirillales	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
DYD1_k127_2744635_4	344747.PM8797T_22113	1.919e-79	277.0	COG0240@1|root,COG0240@2|Bacteria,2IWWN@203682|Planctomycetes	203682|Planctomycetes	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
DYD1_k127_2744635_24	765420.OSCT_2567	1.058e-22	110.0	COG2267@1|root,COG2267@2|Bacteria,2GAN6@200795|Chloroflexi,376TU@32061|Chloroflexia	32061|Chloroflexia	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
DYD1_k127_2744635_22	1123288.SOV_3c04560	5.953e-29	129.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H408@909932|Negativicutes	909932|Negativicutes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DYD1_k127_2744635_14	1121945.ATXS01000001_gene2420	9.847e-51	189.0	COG0434@1|root,arCOG01982@2157|Archaea,2XT9I@28890|Euryarchaeota,23T8W@183963|Halobacteria	183963|Halobacteria	S	photosystem I assembly BtpA	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
DYD1_k127_2744635_25	1469607.KK073768_gene1430	9.352e-09	64.0	COG0746@1|root,COG0746@2|Bacteria,1G587@1117|Cyanobacteria,1HIVV@1161|Nostocales	1117|Cyanobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DYD1_k127_2744635_23	266117.Rxyl_1548	8.64e-23	112.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4CRKQ@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
DYD1_k127_2744635_12	509191.AEDB02000108_gene1632	5.035e-56	205.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WIP2@541000|Ruminococcaceae	186801|Clostridia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DYD1_k127_2744635_11	1041930.Mtc_1643	5.173e-59	224.0	COG0644@1|root,arCOG00570@2157|Archaea,2XUI9@28890|Euryarchaeota,2N9DD@224756|Methanomicrobia	224756|Methanomicrobia	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,HI0933_like,Lycopene_cycl
DYD1_k127_2744635_19	273075.Ta1106	6.229e-39	151.0	COG2150@1|root,arCOG02316@2157|Archaea,2XWH9@28890|Euryarchaeota,241VB@183967|Thermoplasmata	183967|Thermoplasmata	S	regulator of amino acid metabolism, contains ACT domain	-	-	-	ko:K07103	-	-	-	-	ko00000	-	-	-	ACT
DYD1_k127_2744635_9	1448860.BBJO01000047_gene1665	1.694e-70	251.0	COG1830@1|root,arCOG04044@2157|Archaea,2XTBQ@28890|Euryarchaeota,23SJI@183963|Halobacteria	183963|Halobacteria	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
DYD1_k127_2744635_6	579137.Metvu_0910	6.351e-79	277.0	COG1465@1|root,arCOG04353@2157|Archaea,2XSXD@28890|Euryarchaeota,23QQQ@183939|Methanococci	183939|Methanococci	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
DYD1_k127_2744635_27	1183377.Py04_1626	0.0001075	55.0	COG0169@1|root,arCOG02097@2157|Archaea,2Y6DY@28890|Euryarchaeota,2447X@183968|Thermococci	183968|Thermococci	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
DYD1_k127_2744635_20	1128421.JAGA01000002_gene514	9.867e-36	155.0	COG0169@1|root,COG0169@2|Bacteria,2NPR3@2323|unclassified Bacteria	2|Bacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
DYD1_k127_2744635_18	410358.Mlab_1651	8.658e-42	168.0	COG1685@1|root,arCOG01025@2157|Archaea,2XUI2@28890|Euryarchaeota,2N96J@224756|Methanomicrobia	224756|Methanomicrobia	E	shikimate kinase activity	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A3127	GHMP_kinases_N
DYD1_k127_2744635_10	358396.C445_13702	2.114e-64	242.0	COG0128@1|root,arCOG04134@2157|Archaea,2XTC3@28890|Euryarchaeota,23S46@183963|Halobacteria	183963|Halobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
DYD1_k127_2744635_0	35841.BT1A1_1853	9.964e-97	331.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,1ZB2N@1386|Bacillus	91061|Bacilli	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DYD1_k127_2744635_5	502025.Hoch_6599	4.388e-79	280.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales	28221|Deltaproteobacteria	E	Prephenate dehydrogenase chorismate mutase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
DYD1_k127_2744635_1	573063.Metin_0677	4.46e-87	307.0	COG0527@1|root,arCOG00861@2157|Archaea,2XTJ0@28890|Euryarchaeota,23QME@183939|Methanococci	183939|Methanococci	E	Belongs to the aspartokinase family	-	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
DYD1_k127_2744635_21	264732.Moth_0371	3.789e-29	126.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,249II@186801|Clostridia,42FVW@68295|Thermoanaerobacterales	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DYD1_k127_2805266_1	879212.DespoDRAFT_00944	1.212e-07	58.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ysoA	-	2.8.2.22	ko:K01023,ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	TPR_19,Thioredoxin
DYD1_k127_2805266_2	330084.JNYZ01000016_gene5401	6.5e-07	51.0	COG0640@1|root,COG0640@2|Bacteria,2IHS2@201174|Actinobacteria,4E54D@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
DYD1_k127_2846582_30	555779.Dthio_PD1898	4.616e-15	76.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42MDY@68525|delta/epsilon subdivisions,2WM0T@28221|Deltaproteobacteria,2MGC0@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Restriction endonuclease, type I, EcoRI, R subunit Type III	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N,ResIII
DYD1_k127_2846582_10	673860.AciM339_0069	6.308e-67	249.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUW2@28890|Euryarchaeota,3F2R0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Mechanosensitive ion channel	-	-	-	ko:K03442,ko:K05802,ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.2,1.A.23.4	-	-	MS_channel
DYD1_k127_2846582_5	1254432.SCE1572_23075	2.343e-88	302.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD1_k127_2846582_33	1173264.KI913949_gene2071	1.873e-11	69.0	COG3806@1|root,COG3806@2|Bacteria,1G0B3@1117|Cyanobacteria,1H891@1150|Oscillatoriales	1117|Cyanobacteria	T	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
DYD1_k127_2846582_26	1237500.ANBA01000001_gene5075	1.131e-21	108.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4EI3T@85012|Streptosporangiales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_2846582_0	192952.MM_1387	4.312e-178	591.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,2N9AX@224756|Methanomicrobia	224756|Methanomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,HHH_5,Helicase_C
DYD1_k127_2846582_24	1236689.MMALV_00410	5.572e-26	109.0	COG1698@1|root,arCOG04308@2157|Archaea,2XZVX@28890|Euryarchaeota,3F2TA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterised protein family (UPF0147)	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
DYD1_k127_2846582_11	634498.mru_0145	4.796e-63	219.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,23P0H@183925|Methanobacteria	183925|Methanobacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DYD1_k127_2846582_18	368407.Memar_2279	2.793e-41	160.0	COG0704@1|root,arCOG00232@2157|Archaea,2XUZ9@28890|Euryarchaeota,2N9W2@224756|Methanomicrobia	224756|Methanomicrobia	P	Plays a role in the regulation of phosphate uptake	phoU-2	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
DYD1_k127_2846582_4	1121456.ATVA01000018_gene368	4.817e-99	331.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2M7VZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
DYD1_k127_2846582_12	518766.Rmar_1827	9.425e-63	226.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1FIYE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DYD1_k127_2846582_8	394503.Ccel_2103	1.485e-73	261.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,36DTN@31979|Clostridiaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
DYD1_k127_2846582_15	1444309.JAQG01000110_gene1804	4.445e-57	211.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli	91061|Bacilli	P	phosphate	pstS	GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
DYD1_k127_2846582_25	253839.SSNG_05822	5.573e-23	109.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
DYD1_k127_2846582_9	1094980.Mpsy_1566	1.319e-68	248.0	COG3389@1|root,arCOG04463@2157|Archaea,2XSZT@28890|Euryarchaeota,2N9I2@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART Peptidase A22, presenilin signal peptide	-	-	-	-	-	-	-	-	-	-	-	-	SPP
DYD1_k127_2846582_13	485913.Krac_10511	1.31e-60	222.0	COG0284@1|root,COG0284@2|Bacteria,2G692@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
DYD1_k127_2846582_37	208444.JNYY01000006_gene6879	3.02e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,2INUN@201174|Actinobacteria,4EDQS@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,NB-ARC,TPR_12,TPR_7
DYD1_k127_2846582_17	1177154.Y5S_03077	5.054e-46	181.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1XHXW@135619|Oceanospirillales	135619|Oceanospirillales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
DYD1_k127_2846582_7	309801.trd_A0395	1.927e-86	307.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
DYD1_k127_2846582_31	745776.DGo_CA1188	1.346e-13	79.0	COG3603@1|root,COG3603@2|Bacteria,1WN1I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG3603 conserved	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
DYD1_k127_2846582_22	935837.JAEK01000001_gene2313	9.52e-29	128.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,1ZBG2@1386|Bacillus	91061|Bacilli	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation	lipM	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DYD1_k127_2846582_6	204669.Acid345_3835	2.154e-87	310.0	COG0531@1|root,COG0531@2|Bacteria,3Y6HV@57723|Acidobacteria,2JMCG@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DYD1_k127_2846582_38	665959.HMPREF1013_02782	0.0003977	53.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,1ZE6M@1386|Bacillus	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_2846582_28	1380390.JIAT01000012_gene3302	2.861e-21	108.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2846582_34	1123023.JIAI01000004_gene8007	5.338e-09	69.0	COG5276@1|root,COG5276@2|Bacteria,2H0YK@201174|Actinobacteria	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_2846582_39	1137271.AZUM01000003_gene3748	0.0007922	53.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4EA60@85010|Pseudonocardiales	201174|Actinobacteria	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,PKD,ThuA
DYD1_k127_2846582_1	330214.NIDE1541	1.312e-133	460.0	COG1203@1|root,COG1203@2|Bacteria,3J1DM@40117|Nitrospirae	40117|Nitrospirae	L	CRISPR-associated helicase Cas3	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,Helicase_C
DYD1_k127_2846582_14	1049564.TevJSym_bz00080	1.685e-59	229.0	arCOG04928@1|root,2Z880@2|Bacteria,1NBNZ@1224|Proteobacteria,1RQGK@1236|Gammaproteobacteria,1J5EF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CRISPR-associated protein Cse1 (CRISPR_cse1)	casA	GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0006950,GO:0006952,GO:0008150,GO:0008270,GO:0009605,GO:0009607,GO:0009615,GO:0043167,GO:0043169,GO:0043207,GO:0046872,GO:0046914,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0097159,GO:0098542,GO:1901363	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
DYD1_k127_2846582_36	349163.Acry_1812	3.189e-07	59.0	2EMUR@1|root,33FH1@2|Bacteria,1NGE1@1224|Proteobacteria,2UNFG@28211|Alphaproteobacteria,2JUJ2@204441|Rhodospirillales	204441|Rhodospirillales	S	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse2
DYD1_k127_2846582_3	1238190.AMQY01000010_gene2438	2.812e-105	352.0	COG1857@1|root,COG1857@2|Bacteria,1MVNH@1224|Proteobacteria,1RMBZ@1236|Gammaproteobacteria,1XHNF@135619|Oceanospirillales	135619|Oceanospirillales	L	CRISPR-associated protein, Cse4	-	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
DYD1_k127_2846582_19	1150469.RSPPHO_02012	2.5e-40	159.0	2DBE4@1|root,2Z8QG@2|Bacteria,1RAK5@1224|Proteobacteria,2U7R4@28211|Alphaproteobacteria,2JUSI@204441|Rhodospirillales	204441|Rhodospirillales	S	CRISPR-associated protein (Cas_Cas5)	-	-	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
DYD1_k127_2846582_23	1380358.JADJ01000016_gene3563	4.52e-27	119.0	28PYB@1|root,2ZCI1@2|Bacteria,1R36H@1224|Proteobacteria,1T63X@1236|Gammaproteobacteria,1XJYK@135619|Oceanospirillales	135619|Oceanospirillales	S	CRISPR_assoc	-	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
DYD1_k127_2846582_2	519989.ECTPHS_09749	1.093e-113	376.0	COG1518@1|root,COG1518@2|Bacteria,1MUXH@1224|Proteobacteria,1RP48@1236|Gammaproteobacteria,1WWUI@135613|Chromatiales	135613|Chromatiales	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
DYD1_k127_2846582_21	1150469.RSPPHO_02009	5.295e-33	130.0	COG0847@1|root,COG0847@2|Bacteria,1N05B@1224|Proteobacteria,2UC74@28211|Alphaproteobacteria,2JXB5@204441|Rhodospirillales	204441|Rhodospirillales	L	CRISPR-associated protein (Cas_Cas2CT1978)	-	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978
DYD1_k127_2846582_35	269800.Tfu_1326	6.473e-08	55.0	2DH0G@1|root,2ZXYG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2846582_29	243365.CV_1377	5.085e-21	96.0	2DMND@1|root,32SNQ@2|Bacteria,1R37A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2846582_20	243365.CV_1377	3.83e-36	144.0	2DMND@1|root,32SNQ@2|Bacteria,1R37A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2846582_16	243365.CV_1377	7.801e-52	196.0	2DMND@1|root,32SNQ@2|Bacteria,1R37A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2919142_0	1379270.AUXF01000005_gene644	1.036e-74	256.0	28NKC@1|root,2ZBM7@2|Bacteria,1ZUHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_2919142_1	909663.KI867150_gene786	2.882e-58	214.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,42T3U@68525|delta/epsilon subdivisions,2WPDH@28221|Deltaproteobacteria,2MRV1@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DYD1_k127_3009278_1	266748.HY04_12465	0.00014	49.0	COG2963@1|root,COG2963@2|Bacteria,4NQGJ@976|Bacteroidetes,1I2UE@117743|Flavobacteriia,3ZU73@59732|Chryseobacterium	976|Bacteroidetes	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28
DYD1_k127_3009278_0	398767.Glov_0388	1.519e-88	307.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
DYD1_k127_304974_3	1094980.Mpsy_0480	6.623e-33	137.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota	28890|Euryarchaeota	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB1	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DYD1_k127_304974_5	1094980.Mpsy_0483	4.001e-31	134.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota	28890|Euryarchaeota	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB1	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DYD1_k127_304974_6	1094980.Mpsy_0480	1.078e-29	125.0	COG1681@1|root,arCOG01829@2157|Archaea,2XTEE@28890|Euryarchaeota	28890|Euryarchaeota	N	Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella	flaB1	GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K07325	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DYD1_k127_304974_8	1457250.BBMO01000001_gene1780	0.0005415	48.0	COG3353@1|root,arCOG01824@2157|Archaea	2157|Archaea	N	Archaeal flagellar protein F	flaF	-	-	ko:K07329	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DYD1_k127_304974_7	543526.Htur_3558	5.062e-07	57.0	COG3354@1|root,arCOG01822@2157|Archaea,2Y11T@28890|Euryarchaeota,23Y49@183963|Halobacteria	183963|Halobacteria	N	archaeal flagellar protein G	-	-	-	ko:K07330	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DYD1_k127_304974_2	1094980.Mpsy_2349	7.749e-53	195.0	COG2874@1|root,arCOG04148@2157|Archaea,2XUMD@28890|Euryarchaeota,2N9IB@224756|Methanomicrobia	224756|Methanomicrobia	N	KaiC	-	-	-	ko:K07331	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ATPase
DYD1_k127_304974_0	573063.Metin_1102	1.154e-184	594.0	COG4962@1|root,arCOG01817@2157|Archaea,2XTDM@28890|Euryarchaeota,23Q0D@183939|Methanococci	183939|Methanococci	N	PFAM Type II secretion system protein E	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DYD1_k127_304974_1	243232.MJ_0900	7.336e-170	553.0	COG4962@1|root,arCOG01817@2157|Archaea,2XTDM@28890|Euryarchaeota,23Q0D@183939|Methanococci	183939|Methanococci	N	PFAM Type II secretion system protein E	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DYD1_k127_304974_4	693661.Arcve_1470	3.915e-32	131.0	COG1955@1|root,arCOG01809@2157|Archaea,2XTAX@28890|Euryarchaeota,246UJ@183980|Archaeoglobi	183980|Archaeoglobi	N	PFAM Type II secretion system F domain	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DYD1_k127_3058103_1	392500.Swoo_3537	6.338e-46	173.0	28PFH@1|root,2ZC6N@2|Bacteria,1RE9A@1224|Proteobacteria,1S4BF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4272)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4272
DYD1_k127_3058103_0	1235457.C404_04255	3.63e-61	214.0	2AMAC@1|root,31C5B@2|Bacteria,1RI20@1224|Proteobacteria,2VSXR@28216|Betaproteobacteria,1KDH1@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
DYD1_k127_3058103_3	1120999.JONM01000007_gene1693	1.187e-05	53.0	28V1N@1|root,2ZH55@2|Bacteria,1P6C5@1224|Proteobacteria,2W6H5@28216|Betaproteobacteria,2KTF3@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3058103_4	1461579.CCNK01000027_gene774	0.000308	49.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1Y86M@135625|Pasteurellales	135625|Pasteurellales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DYD1_k127_3058103_2	1123053.AUDG01000004_gene3399	1.333e-21	99.0	2EQH0@1|root,33I30@2|Bacteria,1NJ7T@1224|Proteobacteria,1S9N1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3108749_21	1033806.HTIA_0843	2.137e-23	105.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,23SS9@183963|Halobacteria	183963|Halobacteria	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
DYD1_k127_3108749_25	523850.TON_0811	3.847e-14	87.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,2440W@183968|Thermococci	28890|Euryarchaeota	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
DYD1_k127_3108749_20	243232.MJ_0040	1.731e-25	109.0	COG2139@1|root,arCOG04129@2157|Archaea,2XXZB@28890|Euryarchaeota,23R0X@183939|Methanococci	183939|Methanococci	J	Belongs to the eukaryotic ribosomal protein eL21 family	rpl21e	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02889	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21e
DYD1_k127_3108749_26	304371.MCP_0724	6.116e-14	76.0	COG1460@1|root,arCOG01016@2157|Archaea,2XXZX@28890|Euryarchaeota,2N9UM@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM RNA polymerase Rpb4	rpoF	-	2.7.7.6	ko:K03051	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb4
DYD1_k127_3108749_14	439481.Aboo_0763	3.804e-57	208.0	COG1491@1|root,arCOG04130@2157|Archaea,2XXAI@28890|Euryarchaeota,3F2KH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Helix-hairpin-helix motif	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
DYD1_k127_3108749_16	523845.AQXV01000055_gene30	8.322e-46	179.0	COG0030@1|root,arCOG04131@2157|Archaea,2XU1Q@28890|Euryarchaeota,23QM5@183939|Methanococci	183939|Methanococci	J	Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DYD1_k127_3108749_23	402880.MmarC5_1623	2.592e-22	104.0	COG2890@1|root,arCOG00109@2157|Archaea,2XWJZ@28890|Euryarchaeota,23QUN@183939|Methanococci	183939|Methanococci	J	PFAM methyltransferase small	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,PrmA
DYD1_k127_3108749_15	529709.PYCH_08260	7.833e-46	176.0	COG2519@1|root,arCOG00978@2157|Archaea,2XTV7@28890|Euryarchaeota,2439X@183968|Thermococci	183968|Thermococci	J	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
DYD1_k127_3108749_6	662479.C440_07362	6.033e-82	279.0	COG2013@1|root,arCOG01907@2157|Archaea,2XW0I@28890|Euryarchaeota,23U3H@183963|Halobacteria	183963|Halobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
DYD1_k127_3108749_10	84531.JMTZ01000014_gene2827	2.023e-66	249.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1X8D9@135614|Xanthomonadales	135614|Xanthomonadales	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
DYD1_k127_3108749_32	1122609.AUGT01000015_gene1974	2.482e-07	62.0	2DK6R@1|root,32UEG@2|Bacteria,2INPY@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
DYD1_k127_3108749_13	265729.GS18_0219980	9.512e-58	208.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,1ZB1C@1386|Bacillus	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DYD1_k127_3108749_4	1192034.CAP_4850	7.592e-116	393.0	COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,42U01@68525|delta/epsilon subdivisions,2WQQ3@28221|Deltaproteobacteria,2YU39@29|Myxococcales	28221|Deltaproteobacteria	C	homogentisate 12-dioxygenase	hgo	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
DYD1_k127_3108749_3	197221.22294485	2.23e-117	392.0	COG0014@1|root,COG0014@2|Bacteria,1G1NS@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DYD1_k127_3108749_7	1094980.Mpsy_1152	1.399e-78	276.0	COG0263@1|root,arCOG00864@2157|Archaea,2XV1I@28890|Euryarchaeota,2NAAX@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
DYD1_k127_3108749_18	864073.HFRIS_013154	2.042e-30	133.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,2VIB3@28216|Betaproteobacteria,4736E@75682|Oxalobacteraceae	28216|Betaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DYD1_k127_3108749_11	1041930.Mtc_1240	3.231e-60	221.0	COG0467@1|root,arCOG01171@2157|Archaea,2XTXF@28890|Euryarchaeota,2NBFR@224756|Methanomicrobia	224756|Methanomicrobia	T	DnaB-like helicase C terminal domain	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
DYD1_k127_3108749_19	1274524.BSONL12_11791	1.203e-29	136.0	COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZDWU@1386|Bacillus	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	kinC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K07698	ko02020,map02020	M00485	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
DYD1_k127_3108749_9	1169144.KB910935_gene2000	8.512e-67	237.0	COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,1ZCD1@1386|Bacillus	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
DYD1_k127_3108749_5	1254432.SCE1572_35535	1.086e-93	323.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,42R5V@68525|delta/epsilon subdivisions,2WMYF@28221|Deltaproteobacteria,2YU6U@29|Myxococcales	28221|Deltaproteobacteria	C	dioxygenase	hppD	-	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
DYD1_k127_3108749_8	1125971.ASJB01000028_gene8011	4.408e-70	244.0	COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria,4E08E@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DYD1_k127_3108749_2	58123.JOFJ01000021_gene3929	1.284e-153	507.0	COG4677@1|root,COG4677@2|Bacteria,2GNHF@201174|Actinobacteria,4EFJG@85012|Streptosporangiales	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
DYD1_k127_3108749_1	368407.Memar_1325	2.249e-155	502.0	COG1850@1|root,arCOG04443@2157|Archaea,2XVBP@28890|Euryarchaeota,2N9IP@224756|Methanomicrobia	224756|Methanomicrobia	G	Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase	rbcL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0902	RuBisCO_large,RuBisCO_large_N
DYD1_k127_3108749_22	192952.MM_1927	3.801e-23	115.0	arCOG02526@1|root,arCOG02526@2157|Archaea	2157|Archaea	O	Parallel beta-helix	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,CHB_HEX_C_1,CarboxypepD_reg,DUF11,NosD,PKD
DYD1_k127_3108749_12	1122138.AQUZ01000029_gene4831	8.81e-59	224.0	COG1073@1|root,COG1073@2|Bacteria,2ID35@201174|Actinobacteria,4DWKD@85009|Propionibacteriales	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S15
DYD1_k127_3108749_27	751945.Theos_0308	7.658e-14	83.0	COG0697@1|root,COG0697@2|Bacteria,1WIMI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
DYD1_k127_3108749_24	1121878.AUGL01000021_gene2818	9.427e-22	104.0	2EUCM@1|root,33MV1@2|Bacteria,1N3HH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3108749_0	436308.Nmar_1477	9.263e-207	670.0	COG0525@1|root,arCOG00808@2157|Archaea,41SBK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Anticodon-binding domain of tRNA	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DYD1_k127_3108749_30	935839.JAGJ01000012_gene3000	3.603e-09	64.0	COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria,4F4YE@85017|Promicromonosporaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
DYD1_k127_3108749_33	1227454.C446_09975	0.0006452	48.0	arCOG08146@1|root,arCOG08146@2157|Archaea,2Y15V@28890|Euryarchaeota	28890|Euryarchaeota	K	Pfam:DUF217	-	-	-	-	-	-	-	-	-	-	-	-	VAPB_antitox
DYD1_k127_3108749_29	497321.C664_05166	1.582e-09	59.0	2DMND@1|root,32SNQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3108749_28	497321.C664_05166	1.393e-10	64.0	2DMND@1|root,32SNQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3135629_1	1384066.JAGT01000001_gene1676	0.0002007	52.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190,DUF4339
DYD1_k127_3135629_0	2055.JNXA01000002_gene2614	8.278e-11	70.0	2EGCD@1|root,33A46@2|Bacteria,2I3NP@201174|Actinobacteria,4GCTS@85026|Gordoniaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
DYD1_k127_3158166_0	1094980.Mpsy_1119	2.569e-99	338.0	COG0130@1|root,arCOG00987@2157|Archaea,2XTUE@28890|Euryarchaeota,2N99I@224756|Methanomicrobia	224756|Methanomicrobia	J	Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177,ko:K11131	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016,ko03032	-	-	-	DKCLD,PUA,TruB_C_2,TruB_N
DYD1_k127_3158166_2	1094980.Mpsy_1082	1.738e-33	137.0	COG0575@1|root,arCOG04106@2157|Archaea,2XWNR@28890|Euryarchaeota,2N9PZ@224756|Methanomicrobia	224756|Methanomicrobia	I	Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids	carS	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
DYD1_k127_3158166_5	1114856.C496_01426	0.0003135	50.0	arCOG02416@1|root,arCOG02416@2157|Archaea,2Y0IU@28890|Euryarchaeota,23XUU@183963|Halobacteria	183963|Halobacteria	N	TIGRFAM archaeal flagellin N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Pilin_N
DYD1_k127_3158166_3	29540.C481_09243	7.232e-32	143.0	COG1520@1|root,arCOG02482@2157|Archaea,2XUI1@28890|Euryarchaeota,240TC@183963|Halobacteria	183963|Halobacteria	C	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DYD1_k127_3158166_4	68219.JNXI01000002_gene3952	8.069e-18	96.0	COG1290@1|root,COG1290@2|Bacteria,2ICE4@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b/b6/petB	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_N_2
DYD1_k127_3158166_1	529709.PYCH_11380	3.565e-56	214.0	COG1409@1|root,COG1750@1|root,arCOG01144@2157|Archaea,arCOG01937@2157|Archaea,2XUEB@28890|Euryarchaeota,242IS@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase S16 family	-	-	-	ko:K06870	-	-	-	-	ko00000	-	-	-	Lon_C
DYD1_k127_316009_1	215803.DB30_1458	1.133e-09	64.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
DYD1_k127_3180320_4	1183438.GKIL_0281	4.712e-15	79.0	COG1208@1|root,COG1208@2|Bacteria,1G168@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate	cugP	GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DYD1_k127_3180320_3	1457250.BBMO01000002_gene2522	1.121e-19	94.0	COG1259@1|root,arCOG01759@2157|Archaea,2XWIM@28890|Euryarchaeota,23VKG@183963|Halobacteria	183963|Halobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
DYD1_k127_3180320_0	439481.Aboo_0834	4.216e-34	138.0	COG1056@1|root,arCOG00972@2157|Archaea,2XUF7@28890|Euryarchaeota,3F2N0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Cytidylyltransferase-like	nadM	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DYD1_k127_3180320_1	478741.JAFS01000001_gene1979	1.732e-28	124.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia,37GB6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DYD1_k127_3180320_2	694430.Natoc_0254	2.009e-28	126.0	COG1746@1|root,arCOG04249@2157|Archaea,2XT5J@28890|Euryarchaeota,23SC2@183963|Halobacteria	183963|Halobacteria	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
DYD1_k127_3195658_40	1408473.JHXO01000001_gene2211	4.167e-14	81.0	COG5523@1|root,COG5523@2|Bacteria,4NM5R@976|Bacteroidetes	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
DYD1_k127_3195658_8	523850.TON_1836	3.699e-95	323.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTRS@28890|Euryarchaeota,242JW@183968|Thermococci	183968|Thermococci	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DYD1_k127_3195658_39	323259.Mhun_0933	8.316e-16	87.0	COG2426@1|root,arCOG01330@2157|Archaea,2Y4KG@28890|Euryarchaeota	28890|Euryarchaeota	S	Small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
DYD1_k127_3195658_25	868131.MSWAN_2120	2.622e-45	177.0	COG0513@1|root,arCOG00078@2157|Archaea,2XTFM@28890|Euryarchaeota,23NY5@183925|Methanobacteria	183925|Methanobacteria	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	-	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
DYD1_k127_3195658_13	1054217.TALC_00245	4.848e-67	241.0	COG1498@1|root,arCOG01923@2157|Archaea,2XUEA@28890|Euryarchaeota,241U5@183967|Thermoplasmata	183967|Thermoplasmata	J	snoRNA binding domain, fibrillarin	-	-	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
DYD1_k127_3195658_11	1236689.MMALV_07220	2.028e-83	287.0	COG0167@1|root,arCOG00603@2157|Archaea,2XTMB@28890|Euryarchaeota,3F2FC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DYD1_k127_3195658_10	744979.R2A130_1496	1.971e-88	316.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	MA20_19425	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DYD1_k127_3195658_24	1123242.JH636435_gene1914	4.107e-49	184.0	COG3752@1|root,COG3752@2|Bacteria,2IZ0I@203682|Planctomycetes	203682|Planctomycetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
DYD1_k127_3195658_43	1387312.BAUS01000012_gene2156	8.366e-08	57.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2VQHY@28216|Betaproteobacteria,2KKZM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
DYD1_k127_3195658_41	177439.DP2153	5.417e-14	76.0	2CG94@1|root,337GB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3195658_0	1123389.ATXJ01000002_gene1468	7.538e-164	532.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
DYD1_k127_3195658_6	1379698.RBG1_1C00001G0806	1.697e-105	353.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD1_k127_3195658_5	1121127.JAFA01000050_gene7698	4.376e-110	370.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,1K4AM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
DYD1_k127_3195658_38	1440053.JOEI01000002_gene3581	1.666e-19	102.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_3195658_14	864051.BurJ1DRAFT_3799	1.99e-64	243.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2W5VT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DYD1_k127_3195658_20	1121877.JQKF01000001_gene1402	4.226e-57	214.0	COG3396@1|root,COG3396@2|Bacteria,2GK2T@201174|Actinobacteria	201174|Actinobacteria	S	Phenylacetate-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
DYD1_k127_3195658_42	980584.AFPB01000162_gene2220	2.558e-09	68.0	COG3291@1|root,COG3397@1|root,COG4412@1|root,COG3291@2|Bacteria,COG3397@2|Bacteria,COG4412@2|Bacteria,4PFMJ@976|Bacteroidetes,1I83R@117743|Flavobacteriia	976|Bacteroidetes	S	Lytic polysaccharide mono-oxygenase, cellulose-degrading	-	-	-	-	-	-	-	-	-	-	-	-	LPMO_10
DYD1_k127_3195658_31	1423780.LOT_2037	6.719e-34	144.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae	91061|Bacilli	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DoxX,Pyr_redox_2
DYD1_k127_3195658_4	518766.Rmar_1706	1.606e-111	372.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1FJ2F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
DYD1_k127_3195658_27	1123368.AUIS01000010_gene2414	5.565e-43	181.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1QVXJ@1224|Proteobacteria,1T2NA@1236|Gammaproteobacteria,2NE6W@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
DYD1_k127_3195658_12	1382304.JNIL01000001_gene2953	2.05e-68	241.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,279HF@186823|Alicyclobacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD1_k127_3195658_45	744980.TRICHSKD4_5442	9.708e-05	55.0	293ZC@1|root,2ZREC@2|Bacteria,1RDYU@1224|Proteobacteria,2U7U4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3195658_9	391625.PPSIR1_25066	2.729e-92	311.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DYD1_k127_3195658_15	795797.C497_01570	4.499e-64	229.0	COG1024@1|root,arCOG00239@2157|Archaea,2XTF0@28890|Euryarchaeota,23SMM@183963|Halobacteria	183963|Halobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD1_k127_3195658_17	518766.Rmar_1802	9.912e-64	229.0	COG1834@1|root,COG1834@2|Bacteria,4PECN@976|Bacteroidetes,1FIVN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
DYD1_k127_3195658_19	861299.J421_5582	6.066e-61	221.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DYD1_k127_3195658_29	1048834.TC41_2756	4.982e-38	148.0	COG1853@1|root,COG1853@2|Bacteria,1V1X6@1239|Firmicutes,4HGJ2@91061|Bacilli	91061|Bacilli	S	PFAM flavin reductase domain protein FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DYD1_k127_3195658_7	1382356.JQMP01000001_gene901	1.371e-104	359.0	COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
DYD1_k127_3195658_23	1294273.roselon_02378	3.575e-50	188.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD1_k127_3195658_1	1227484.C471_08950	2.595e-147	482.0	COG1012@1|root,arCOG01252@2157|Archaea,2XT1Y@28890|Euryarchaeota,23SU2@183963|Halobacteria	183963|Halobacteria	C	COG1012 NAD-dependent aldehyde dehydrogenases	aldY5	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DYD1_k127_3195658_35	342113.DM82_5774	1.208e-22	106.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,2VIT3@28216|Betaproteobacteria,1K5CY@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
DYD1_k127_3195658_30	313606.M23134_05224	1.99e-36	154.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,47PHD@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_3195658_2	309807.SRU_2042	8.503e-134	437.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	HP	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
DYD1_k127_3195658_26	797303.Natpe_1420	3.911e-43	172.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUHN@28890|Euryarchaeota,23THM@183963|Halobacteria	183963|Halobacteria	M	COG0668 Small-conductance mechanosensitive channel	mscS5	-	-	-	-	-	-	-	-	-	-	-	MS_channel
DYD1_k127_3195658_33	266117.Rxyl_0090	1.75e-23	113.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4CTMT@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
DYD1_k127_3195658_16	1206733.BAGC01000041_gene1874	5.791e-64	236.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4FXF4@85025|Nocardiaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_3195658_44	649831.L083_0516	2.406e-07	59.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4DDS4@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
DYD1_k127_3195658_34	1123405.AUMM01000027_gene2137	2.86e-23	101.0	COG1146@1|root,COG1146@2|Bacteria,1TXPN@1239|Firmicutes,4HKY3@91061|Bacilli,26PWX@186821|Sporolactobacillaceae	91061|Bacilli	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7
DYD1_k127_3195658_18	321332.CYB_0991	3.473e-62	227.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,1GYMC@1129|Synechococcus	1117|Cyanobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DYD1_k127_3195658_28	1162668.LFE_2058	3.406e-40	152.0	COG0011@1|root,COG0011@2|Bacteria,3J0QD@40117|Nitrospirae	40117|Nitrospirae	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
DYD1_k127_3195658_21	469382.Hbor_11740	1.551e-56	210.0	arCOG04564@1|root,arCOG04564@2157|Archaea,2XTME@28890|Euryarchaeota,23SGS@183963|Halobacteria	183963|Halobacteria	S	PFAM DoxX family protein	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
DYD1_k127_3195658_22	485913.Krac_9606	2.524e-56	211.0	COG2267@1|root,COG2267@2|Bacteria,2G8RT@200795|Chloroflexi	200795|Chloroflexi	I	Alpha/beta hydrolase family	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
DYD1_k127_3195658_3	547559.Nmag_0596	3.014e-118	393.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,23SC3@183963|Halobacteria	183963|Halobacteria	I	COG0183 Acetyl-CoA acetyltransferase	acaB2	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD1_k127_3195658_37	1227487.C474_16599	7.666e-20	103.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,23TJ1@183963|Halobacteria	183963|Halobacteria	I	COG3425 3-hydroxy-3-methylglutaryl CoA synthase	acaA	-	2.3.3.10	ko:K01641,ko:K07068	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
DYD1_k127_3195658_36	1047013.AQSP01000106_gene1780	1.361e-22	107.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
DYD1_k127_3195658_32	720554.Clocl_3262	1.012e-25	124.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,3WGZ6@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
DYD1_k127_3281194_12	1144275.COCOR_01038	1.36e-12	70.0	COG0656@1|root,COG0656@2|Bacteria,1QX4X@1224|Proteobacteria,43BXP@68525|delta/epsilon subdivisions,2X78G@28221|Deltaproteobacteria,2YTSM@29|Myxococcales	28221|Deltaproteobacteria	S	Aldo keto	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DYD1_k127_3281194_3	1384054.N790_10230	3.758e-75	262.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1X4I1@135614|Xanthomonadales	135614|Xanthomonadales	P	Sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
DYD1_k127_3281194_7	1210908.HSB1_00950	5.341e-48	183.0	COG0384@1|root,arCOG02256@2157|Archaea,2XUVT@28890|Euryarchaeota,23T3Z@183963|Halobacteria	183963|Halobacteria	S	epimerase, PhzC PhzF homolog	phzC	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
DYD1_k127_3281194_11	765698.Mesci_0741	1.119e-12	74.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,1RCN9@1224|Proteobacteria,2U878@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CDGSH-type zinc finger. Function unknown.	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,Ferritin-like,zf-CDGSH
DYD1_k127_3281194_10	1122915.AUGY01000084_gene6180	3.478e-20	97.0	COG4430@1|root,COG4430@2|Bacteria,1VG0C@1239|Firmicutes,4HQHY@91061|Bacilli,277PA@186822|Paenibacillaceae	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3281194_8	1379698.RBG1_1C00001G1377	9.449e-24	117.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
DYD1_k127_3281194_16	877415.JNJQ01000039_gene2593	0.0001993	51.0	COG1180@1|root,COG1846@1|root,COG1180@2|Bacteria,COG1846@2|Bacteria,1V1GP@1239|Firmicutes,3VP52@526524|Erysipelotrichia	526524|Erysipelotrichia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,MarR,MarR_2,Radical_SAM
DYD1_k127_3281194_15	326297.Sama_3361	6.085e-05	53.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,2Q9E5@267890|Shewanellaceae	1236|Gammaproteobacteria	G	hydrolase, subfamily IA, variant 3	gph	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756	HAD_2
DYD1_k127_3281194_13	1291050.JAGE01000002_gene3742	2.963e-12	76.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
DYD1_k127_3281194_5	285514.JNWO01000019_gene7714	8.865e-51	190.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	fbpC	-	-	ko:K02052,ko:K02062	ko02010,ko02024,map02010,map02024	M00191,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.19	-	-	ABC_tran,TOBE_2
DYD1_k127_3281194_4	67281.JNZZ01000024_gene4748	3.385e-70	259.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,4188P@629295|Streptomyces griseus group	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	thiP	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1
DYD1_k127_3281194_6	765420.OSCT_0522	1.084e-50	196.0	COG4143@1|root,COG4143@2|Bacteria,2G615@200795|Chloroflexi,376Q5@32061|Chloroflexia	32061|Chloroflexia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
DYD1_k127_3281194_0	1323663.AROI01000010_gene3368	1.464e-269	845.0	COG0507@1|root,COG1974@1|root,COG3410@1|root,COG0507@2|Bacteria,COG1974@2|Bacteria,COG3410@2|Bacteria,1R703@1224|Proteobacteria,1RY5E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
DYD1_k127_3281194_9	368407.Memar_1489	4.235e-21	104.0	COG1611@1|root,arCOG02431@2157|Archaea,2XZJU@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM SMF family protein	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
DYD1_k127_3281194_2	290397.Adeh_3916	4.29e-101	336.0	COG0842@1|root,COG0842@2|Bacteria,1R3XD@1224|Proteobacteria	1224|Proteobacteria	V	transport, permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
DYD1_k127_3281194_1	290397.Adeh_3915	1.215e-121	398.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2YUI5@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
DYD1_k127_3281194_14	1121104.AQXH01000003_gene329	3.647e-10	72.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase
DYD1_k127_3294552_0	1123261.AXDW01000005_gene2695	4.743e-140	449.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,1RQQ9@1236|Gammaproteobacteria,1X32T@135614|Xanthomonadales	135614|Xanthomonadales	IQ	dehydrogenase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short,adh_short_C2
DYD1_k127_3294552_2	1122603.ATVI01000008_gene2234	8.35e-62	219.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1X5XX@135614|Xanthomonadales	135614|Xanthomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
DYD1_k127_3294552_1	314278.NB231_14973	9.863e-64	223.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1X0VZ@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
DYD1_k127_3317972_9	1122939.ATUD01000001_gene643	2.97e-07	58.0	COG3268@1|root,COG3268@2|Bacteria,2GMKU@201174|Actinobacteria,4CSJP@84995|Rubrobacteria	84995|Rubrobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
DYD1_k127_3317972_8	518766.Rmar_1012	9.931e-08	59.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,1FJW3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_9,Response_reg
DYD1_k127_3317972_2	1157708.KB907460_gene1472	1.861e-144	471.0	COG2519@1|root,COG2519@2|Bacteria,1QWVH@1224|Proteobacteria,2WH1E@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DYD1_k127_3317972_7	1382306.JNIM01000001_gene1793	5.288e-10	68.0	COG1765@1|root,COG1765@2|Bacteria,2G7BY@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DYD1_k127_3317972_6	439481.Aboo_0364	1.21e-12	78.0	COG1522@1|root,arCOG01586@2157|Archaea,2Y6Z8@28890|Euryarchaeota,3F2Z8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
DYD1_k127_3317972_3	118166.JH976537_gene3679	1.935e-68	241.0	COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,1HA80@1150|Oscillatoriales	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
DYD1_k127_3317972_4	304371.MCP_1496	9.02e-22	106.0	COG5549@1|root,arCOG04994@2157|Archaea,2Y4E9@28890|Euryarchaeota	28890|Euryarchaeota	O	Matrixin	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3317972_1	1120919.AUBI01000001_gene3061	2.186e-150	492.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2JPBR@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DYD1_k127_3317972_5	679201.HMPREF9334_01553	6.455e-16	87.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes	909932|Negativicutes	I	glutaconyl-CoA decarboxylase subunit gamma	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
DYD1_k127_3317972_0	1457250.BBMO01000001_gene364	9.714e-184	587.0	COG4799@1|root,arCOG02705@2157|Archaea,2XUNE@28890|Euryarchaeota,23U1N@183963|Halobacteria	183963|Halobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB1	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
DYD1_k127_3407385_0	856793.MICA_2364	2.018e-46	183.0	COG4447@1|root,COG4447@2|Bacteria,1NEB9@1224|Proteobacteria,2UGQQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3432179_6	192952.MM_1111	1.686e-36	148.0	COG0125@1|root,arCOG01891@2157|Archaea,2XTAM@28890|Euryarchaeota,2N9Y8@224756|Methanomicrobia	224756|Methanomicrobia	F	PFAM thymidylate kinase	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
DYD1_k127_3432179_3	604331.AUHY01000058_gene1343	1.555e-63	228.0	2CEY7@1|root,2Z8CG@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3432179_0	110319.CF8_3072	8.675e-250	784.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DPTE@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DYD1_k127_3432179_1	1379698.RBG1_1C00001G0452	8.282e-99	329.0	COG0479@1|root,COG0479@2|Bacteria,2NPY8@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
DYD1_k127_3432179_9	1007103.AFHW01000177_gene2519	3.777e-28	120.0	COG2050@1|root,COG2050@2|Bacteria,1VD4E@1239|Firmicutes,4HKC8@91061|Bacilli,272C2@186822|Paenibacillaceae	91061|Bacilli	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DYD1_k127_3432179_13	266117.Rxyl_1265	8.639e-21	101.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,2I4MX@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
DYD1_k127_3432179_8	1043493.BBLU01000005_gene1946	9.308e-33	139.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
DYD1_k127_3432179_5	58344.JOEL01000036_gene4113	2.067e-39	160.0	COG0697@1|root,COG0697@2|Bacteria,2GNSA@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter DMT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_3432179_11	1463917.JODC01000007_gene7491	2.686e-25	109.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
DYD1_k127_3432179_4	426114.THI_1819	3.618e-62	222.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,1KJRR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
DYD1_k127_3432179_12	1214242.B446_18790	2.369e-24	119.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
DYD1_k127_3432179_7	84531.JMTZ01000114_gene2013	1.214e-34	150.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1PDUK@1224|Proteobacteria,1S8QS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC,Peptidase_M43
DYD1_k127_3432179_2	1278073.MYSTI_01141	4.123e-78	269.0	COG0656@1|root,COG0656@2|Bacteria,1QX4X@1224|Proteobacteria,43BXP@68525|delta/epsilon subdivisions,2X78G@28221|Deltaproteobacteria,2YTSM@29|Myxococcales	28221|Deltaproteobacteria	S	Aldo keto	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DYD1_k127_356295_0	771875.Ferpe_0712	4.476e-24	116.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
DYD1_k127_3564049_1	84531.JMTZ01000014_gene2827	4.499e-45	185.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1X8D9@135614|Xanthomonadales	135614|Xanthomonadales	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
DYD1_k127_3564049_0	1121937.AUHJ01000004_gene1030	3.175e-48	184.0	COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,466EX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
DYD1_k127_3564049_4	330214.NIDE1891	8.95e-13	81.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Cytochrom_C,DUF1080,DUF4132,Pkinase
DYD1_k127_3564049_3	1122132.AQYH01000006_gene3353	3.01e-25	116.0	COG0454@1|root,COG0456@2|Bacteria,1Q3NQ@1224|Proteobacteria,2VAD5@28211|Alphaproteobacteria,4BFVJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
DYD1_k127_3564049_6	4006.Lus10041436	0.0006963	48.0	COG0589@1|root,2RZF9@2759|Eukaryota,37V17@33090|Viridiplantae,3GISS@35493|Streptophyta	35493|Streptophyta	T	Universal stress protein A-like protein	-	GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Usp
DYD1_k127_3564049_2	1245471.PCA10_46770	1.212e-34	145.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RS16@1236|Gammaproteobacteria,1YD34@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	lys	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
DYD1_k127_3567635_1	344747.PM8797T_06335	2.741e-18	86.0	COG2730@1|root,COG2730@2|Bacteria,2IWW8@203682|Planctomycetes	203682|Planctomycetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
DYD1_k127_3567635_0	1403819.BATR01000201_gene6600	3.54e-107	361.0	COG2801@1|root,COG2801@2|Bacteria,46VBX@74201|Verrucomicrobia,2IUPH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
DYD1_k127_3627269_62	679926.Mpet_0861	1.364e-09	71.0	COG3398@1|root,arCOG02611@2157|Archaea	679926.Mpet_0861|-	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3627269_47	1123319.AUBE01000015_gene5674	1.117e-22	112.0	2AQV1@1|root,31G37@2|Bacteria,2IEU1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DYD1_k127_3627269_44	391038.Bphy_5328	4.04e-30	128.0	COG3631@1|root,COG3631@2|Bacteria,1RDED@1224|Proteobacteria,2VS1C@28216|Betaproteobacteria,1KFUN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
DYD1_k127_3627269_17	545243.BAEV01000081_gene2956	1.489e-82	292.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,36E67@31979|Clostridiaceae	186801|Clostridia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DYD1_k127_3627269_34	760192.Halhy_6280	6.189e-44	174.0	COG4638@1|root,COG4638@2|Bacteria,4NJ33@976|Bacteroidetes	976|Bacteroidetes	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
DYD1_k127_3627269_2	1089552.KI911559_gene2232	2.772e-163	542.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,2TUT9@28211|Alphaproteobacteria,2JSSA@204441|Rhodospirillales	204441|Rhodospirillales	HJ	Cyanophycin synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
DYD1_k127_3627269_0	344747.PM8797T_27914	2.365e-258	824.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2IXGZ@203682|Planctomycetes	203682|Planctomycetes	M	cyanophycin synthetase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DYD1_k127_3627269_22	1089552.KI911559_gene2231	3.154e-72	253.0	COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,2U4I8@28211|Alphaproteobacteria,2JVEW@204441|Rhodospirillales	204441|Rhodospirillales	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
DYD1_k127_3627269_20	344747.PM8797T_27919	1.17e-74	261.0	COG1446@1|root,COG1446@2|Bacteria	2|Bacteria	E	asparaginase	-	-	3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
DYD1_k127_3627269_51	391615.ABSJ01000020_gene367	2.848e-21	105.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1J5E4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.7.2.8	ko:K00930,ko:K22478	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00259,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255	AA_kinase,NAT
DYD1_k127_3627269_12	292459.STH2890	3.45e-105	358.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
DYD1_k127_3627269_27	429009.Adeg_1833	3.482e-60	226.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,42F2M@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DYD1_k127_3627269_16	673860.AciM339_0890	8.233e-84	289.0	COG0448@1|root,arCOG00912@2157|Archaea,2XTI4@28890|Euryarchaeota,3F2GM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DYD1_k127_3627269_31	1054217.TALC_00627	1.543e-53	209.0	COG0165@1|root,arCOG01748@2157|Archaea,2XUWS@28890|Euryarchaeota,241V8@183967|Thermoplasmata	183967|Thermoplasmata	E	Lyase	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
DYD1_k127_3627269_5	1329516.JPST01000008_gene1969	1.213e-122	406.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,27B6Z@186824|Thermoactinomycetaceae	91061|Bacilli	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
DYD1_k127_3627269_52	342949.PNA2_0493	8.356e-20	98.0	arCOG01806@1|root,arCOG01806@2157|Archaea,2XWT7@28890|Euryarchaeota,243TC@183968|Thermococci	183968|Thermococci	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_7
DYD1_k127_3627269_68	477974.Daud_0983	0.000393	48.0	COG1487@1|root,COG1487@2|Bacteria,1W517@1239|Firmicutes,256YN@186801|Clostridia,266JC@186807|Peptococcaceae	186801|Clostridia	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
DYD1_k127_3627269_69	416348.Hlac_1432	0.0006591	45.0	arCOG08146@1|root,arCOG08146@2157|Archaea,2XZH2@28890|Euryarchaeota,23X8V@183963|Halobacteria	183963|Halobacteria	K	Putative antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	VAPB_antitox
DYD1_k127_3627269_64	1195236.CTER_4538	1.356e-08	65.0	COG2730@1|root,COG3291@1|root,COG2730@2|Bacteria,COG3291@2|Bacteria,1TQHH@1239|Firmicutes,24BQU@186801|Clostridia,3WHQE@541000|Ruminococcaceae	186801|Clostridia	G	Glycoside hydrolase family 44	celA2	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Dockerin_1,Glyco_hydro_44,PKD
DYD1_k127_3627269_45	272844.PAB0322	6.553e-29	123.0	COG1522@1|root,arCOG01580@2157|Archaea,2XWJA@28890|Euryarchaeota,243ZM@183968|Thermococci	183968|Thermococci	K	transcription regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
DYD1_k127_3627269_3	1242864.D187_004919	2.955e-153	496.0	COG0174@1|root,COG0174@2|Bacteria,1NZU7@1224|Proteobacteria	1224|Proteobacteria	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DYD1_k127_3627269_60	1452536.JARE01000039_gene3046	2.893e-10	66.0	2DS51@1|root,33EJB@2|Bacteria,2IM77@201174|Actinobacteria,4FPD7@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
DYD1_k127_3627269_41	1249975.JQLP01000003_gene76	1.411e-35	152.0	COG1361@1|root,COG3266@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes,1HZAG@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
DYD1_k127_3627269_30	1415779.JOMH01000001_gene866	5.215e-57	210.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1X4UM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF1731)	sulA	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
DYD1_k127_3627269_59	314230.DSM3645_01786	2.473e-11	72.0	COG1547@1|root,COG1547@2|Bacteria,2J0XW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
DYD1_k127_3627269_13	1526927.Plano_0450	1.786e-97	342.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,26D4P@186818|Planococcaceae	91061|Bacilli	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DYD1_k127_3627269_11	118166.JH976537_gene3692	8.22e-115	376.0	COG0491@1|root,COG1141@1|root,COG0491@2|Bacteria,COG1141@2|Bacteria,1G3D1@1117|Cyanobacteria,1H7UZ@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
DYD1_k127_3627269_10	1122182.KB903833_gene5397	7.245e-115	381.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DA29@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DYD1_k127_3627269_8	1033802.SSPSH_002546	6.701e-119	391.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the class I fructose-bisphosphate aldolase family	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
DYD1_k127_3627269_38	593117.TGAM_0531	6.51e-37	149.0	COG2263@1|root,arCOG00910@2157|Archaea,2XU4P@28890|Euryarchaeota,24393@183968|Thermococci	183968|Thermococci	J	Conserved hypothetical protein 95	-	-	-	ko:K07579	-	-	-	-	ko00000	-	-	-	MTS,PrmA
DYD1_k127_3627269_23	1220534.B655_2059	1.575e-71	262.0	COG1736@1|root,arCOG04112@2157|Archaea,2XSY5@28890|Euryarchaeota,23NUP@183925|Methanobacteria	183925|Methanobacteria	J	Diphthamide	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
DYD1_k127_3627269_53	643562.Daes_2657	8.707e-17	89.0	COG1296@1|root,COG1296@2|Bacteria,1P6U3@1224|Proteobacteria,42QVQ@68525|delta/epsilon subdivisions,2WMW1@28221|Deltaproteobacteria,2MAJ4@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
DYD1_k127_3627269_42	886293.Sinac_2076	3.29e-33	135.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DYD1_k127_3627269_37	323259.Mhun_2612	4.694e-37	156.0	COG0503@1|root,arCOG00030@2157|Archaea,2XTWM@28890|Euryarchaeota,2N9KI@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis	hpt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	iAF692.Mbar_A1633	Pribosyltran
DYD1_k127_3627269_18	693661.Arcve_0276	1.936e-78	277.0	COG0076@1|root,arCOG00027@2157|Archaea,2XT09@28890|Euryarchaeota,246M6@183980|Archaeoglobi	183980|Archaeoglobi	E	Belongs to the group II decarboxylase family. MfnA subfamily	mfnA	-	4.1.1.11,4.1.1.25	ko:K18933	ko00350,ko00410,ko00680,ko00770,ko01100,ko01110,map00350,map00410,map00680,map00770,map01100,map01110	-	R00489,R00736	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
DYD1_k127_3627269_29	1094980.Mpsy_2090	6.163e-58	205.0	COG0197@1|root,arCOG04113@2157|Archaea,2XTHT@28890|Euryarchaeota,2N9MZ@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the universal ribosomal protein uL16 family	rpl10e	-	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DYD1_k127_3627269_33	420247.Msm_1201	1.774e-52	197.0	COG1968@1|root,arCOG04761@2157|Archaea,2XTYX@28890|Euryarchaeota,23NY7@183925|Methanobacteria	183925|Methanobacteria	I	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DYD1_k127_3627269_25	1121033.AUCF01000001_gene2030	2.67e-67	240.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_3627269_70	1278073.MYSTI_00226	0.0007621	52.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_3627269_7	247490.KSU1_B0642	5.602e-119	399.0	COG0618@1|root,COG1226@1|root,COG0618@2|Bacteria,COG1226@2|Bacteria,2IXHC@203682|Planctomycetes	203682|Planctomycetes	P	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1,TrkA_N
DYD1_k127_3627269_6	268739.Nmlp_2927	7.235e-122	414.0	COG0553@1|root,arCOG00871@2157|Archaea,2XTQ1@28890|Euryarchaeota,23SWF@183963|Halobacteria	183963|Halobacteria	L	COG0553 Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
DYD1_k127_3627269_50	604354.TSIB_0625	5.209e-22	110.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,243KR@183968|Thermococci	183968|Thermococci	S	Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
DYD1_k127_3627269_15	483219.LILAB_12530	4.484e-84	308.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria,2YTX2@29|Myxococcales	28221|Deltaproteobacteria	P	TrkA-C domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
DYD1_k127_3627269_57	1041930.Mtc_2172	6.224e-14	78.0	COG1534@1|root,arCOG01346@2157|Archaea,2XZWJ@28890|Euryarchaeota	28890|Euryarchaeota	J	RNA-binding protein containing KH domain, possibly ribosomal protein	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
DYD1_k127_3627269_56	1042877.GQS_09685	3.399e-14	82.0	COG2023@1|root,arCOG04345@2157|Archaea,2XYX0@28890|Euryarchaeota,244AW@183968|Thermococci	183968|Thermococci	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
DYD1_k127_3627269_43	647113.Metok_1222	6.056e-32	136.0	COG0288@1|root,arCOG02860@2157|Archaea,2XX8F@28890|Euryarchaeota,23QXP@183939|Methanococci	183939|Methanococci	P	PFAM Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
DYD1_k127_3627269_40	1198114.AciX9_0628	1.204e-36	157.0	COG3119@1|root,COG3119@2|Bacteria,3Y5BN@57723|Acidobacteria,2JMEF@204432|Acidobacteriia	204432|Acidobacteriia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
DYD1_k127_3627269_4	234267.Acid_7155	2.54e-134	447.0	COG2264@1|root,COG2264@2|Bacteria,3Y3UA@57723|Acidobacteria	57723|Acidobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DYD1_k127_3627269_24	673860.AciM339_0957	1.342e-69	249.0	COG1084@1|root,arCOG00352@2157|Archaea,2XU5R@28890|Euryarchaeota,3F2J9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Nucleolar GTP-binding protein 1 (NOG1)	gbp4	-	-	ko:K06943	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	MMR_HSR1,NOG1
DYD1_k127_3627269_49	1463901.JOIY01000066_gene3752	3.538e-22	107.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria	201174|Actinobacteria	NU	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
DYD1_k127_3627269_9	1236689.MMALV_01630	1.631e-116	390.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,3F2EV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	PFAM Aminotransferase class I and II	aspC3	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DYD1_k127_3627269_46	314292.VAS14_02371	4.114e-24	107.0	COG2050@1|root,COG2050@2|Bacteria,1RJUX@1224|Proteobacteria,1S6IU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DYD1_k127_3627269_63	1123258.AQXZ01000011_gene1556	6.066e-09	68.0	COG0182@1|root,COG0235@1|root,COG0182@2|Bacteria,COG0235@2|Bacteria,2GJJA@201174|Actinobacteria,4FWRR@85025|Nocardiaceae	201174|Actinobacteria	GJ	Belongs to the EIF-2B alpha beta delta subunits family. MtnA subfamily	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II,IF-2B
DYD1_k127_3627269_35	877455.Metbo_0173	2.495e-42	168.0	COG0054@1|root,arCOG01323@2157|Archaea,2XXXC@28890|Euryarchaeota,23P08@183925|Methanobacteria	183925|Methanobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DYD1_k127_3627269_28	439481.Aboo_0746	3.712e-59	213.0	COG1731@1|root,arCOG01322@2157|Archaea,2XX0K@28890|Euryarchaeota,3F2K2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	6,7-dimethyl-8-ribityllumazine synthase	ribC	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DYD1_k127_3627269_36	439481.Aboo_0747	1.07e-41	163.0	COG0615@1|root,arCOG01222@2157|Archaea,2XX70@28890|Euryarchaeota,3F2RF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme	ribL	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.7.2	ko:K14656	ko00740,ko01100,ko01110,map00740,map01100,map01110	-	R00161	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DYD1_k127_3627269_32	351160.RCIX632	4.622e-53	196.0	COG0108@1|root,arCOG01320@2157|Archaea,2XTDZ@28890|Euryarchaeota,2N9HB@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A1524	DHBP_synthase
DYD1_k127_3627269_54	523850.TON_1230	1.579e-16	81.0	COG1383@1|root,arCOG01885@2157|Archaea,2Y07I@28890|Euryarchaeota,244GA@183968|Thermococci	183968|Thermococci	J	Belongs to the eukaryotic ribosomal protein eS17 family	rps17e	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
DYD1_k127_3627269_66	1134912.AJTV01000021_gene3013	2.249e-07	59.0	COG0776@1|root,COG0776@2|Bacteria,1N6FS@1224|Proteobacteria,2V9XC@28211|Alphaproteobacteria,3708U@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Bacterial DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
DYD1_k127_3627269_65	882086.SacxiDRAFT_3058	1.748e-07	61.0	COG0125@1|root,COG0125@2|Bacteria,2HKRE@201174|Actinobacteria,4E2SW@85010|Pseudonocardiales	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
DYD1_k127_3627269_67	1090318.ATTI01000001_gene2573	3.791e-07	59.0	COG3326@1|root,COG3326@2|Bacteria,1NGR5@1224|Proteobacteria,2UJDY@28211|Alphaproteobacteria,2K6SS@204457|Sphingomonadales	204457|Sphingomonadales	L	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
DYD1_k127_3627269_1	266117.Rxyl_0133	3.83e-180	595.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DYD1_k127_3627269_58	1134912.AJTV01000035_gene2373	2.695e-12	69.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,36X3A@31993|Methylocystaceae	28211|Alphaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DYD1_k127_3627269_21	251221.35211075	4.996e-73	262.0	COG0475@1|root,COG0475@2|Bacteria,1G03Z@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM Sodium hydrogen exchanger family	kefB	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DYD1_k127_3627269_55	1227500.C494_02486	3.314e-15	86.0	COG1522@1|root,arCOG01585@2157|Archaea,2XW1H@28890|Euryarchaeota,23VJ7@183963|Halobacteria	183963|Halobacteria	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	Arc_trans_TRASH,HTH_24,HTH_AsnC-type
DYD1_k127_3627269_48	1197130.BAFM01000006_gene1200	2.68e-22	110.0	arCOG04522@1|root,arCOG04522@2157|Archaea,2XTU5@28890|Euryarchaeota,23U1D@183963|Halobacteria	183963|Halobacteria	O	cytochrome c biogenesis protein	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DYD1_k127_3627269_61	767434.Fraau_2159	3.53e-10	71.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	3.5.1.104	ko:K12057,ko:K22278	-	-	-	-	ko00000,ko01000,ko02044	3.A.7.11.1	-	-	AhpC-TSA,Arylsulfotrans,MauE,Thioredoxin,Thioredoxin_7,VKOR
DYD1_k127_3627269_26	1094980.Mpsy_1424	5.058e-66	231.0	COG0149@1|root,arCOG01087@2157|Archaea,2XTY3@28890|Euryarchaeota,2N9G7@224756|Methanomicrobia	224756|Methanomicrobia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM,ThiG
DYD1_k127_3627269_19	269797.Mbar_A3256	2.425e-77	274.0	COG0452@1|root,arCOG01704@2157|Archaea,2XTZK@28890|Euryarchaeota,2N9EA@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DYD1_k127_3627269_39	1094980.Mpsy_1000	8.685e-37	151.0	COG1829@1|root,arCOG04263@2157|Archaea,2XST6@28890|Euryarchaeota,2N9J3@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM GHMP kinase	-	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF692.Mbar_A3255	GHMP_kinases_N
DYD1_k127_363212_2	797303.Natpe_0297	1.831e-09	66.0	COG1226@1|root,arCOG01964@2157|Archaea,2Y3MW@28890|Euryarchaeota,23ZQX@183963|Halobacteria	183963|Halobacteria	P	PFAM Ion transport	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_363212_4	1122931.AUAE01000007_gene1359	0.0005067	45.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,2FN7F@200643|Bacteroidia,22X45@171551|Porphyromonadaceae	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
DYD1_k127_363212_3	195522.BD01_1207	3.013e-05	57.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,2440W@183968|Thermococci	183968|Thermococci	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_363212_1	673860.AciM339_0679	1.585e-14	85.0	COG1522@1|root,arCOG01586@2157|Archaea,2Y6Z8@28890|Euryarchaeota,3F2Z8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
DYD1_k127_363212_0	1157708.KB907460_gene1359	2.313e-64	229.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria,4AC1Z@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Methyltransferase type 11	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DYD1_k127_3639983_6	1227457.C451_08755	3.726e-40	154.0	COG1746@1|root,arCOG04249@2157|Archaea,2XT5J@28890|Euryarchaeota,23SC2@183963|Halobacteria	183963|Halobacteria	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
DYD1_k127_3639983_13	399549.Msed_1785	1.903e-12	76.0	COG1514@1|root,arCOG01736@2157|Archaea,2XQM6@28889|Crenarchaeota	28889|Crenarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DYD1_k127_3639983_8	439481.Aboo_0804	3.061e-24	110.0	arCOG03379@1|root,arCOG03379@2157|Archaea,2XZH1@28890|Euryarchaeota,3F2PN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3639983_12	1343739.PAP_04555	5.916e-13	81.0	COG1326@1|root,arCOG02680@2157|Archaea,2XW94@28890|Euryarchaeota,243NQ@183968|Thermococci	183968|Thermococci	S	archaeal Zn-finger protein	-	-	-	-	-	-	-	-	-	-	-	-	eIF-5_eIF-2B
DYD1_k127_3639983_16	497964.CfE428DRAFT_2884	0.000146	48.0	2E5PY@1|root,330EK@2|Bacteria,46WXS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3639983_0	304371.MCP_2982	5.063e-139	449.0	COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,2N980@224756|Methanomicrobia	224756|Methanomicrobia	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
DYD1_k127_3639983_7	1006006.Mcup_1518	1.804e-31	131.0	COG0071@1|root,arCOG01833@2157|Archaea,2XQD6@28889|Crenarchaeota	28889|Crenarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DYD1_k127_3639983_2	1220534.B655_2227	2.946e-105	354.0	COG0484@1|root,arCOG02846@2157|Archaea,2XV5D@28890|Euryarchaeota,23NRW@183925|Methanobacteria	183925|Methanobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DYD1_k127_3639983_3	1163617.SCD_n02577	1.41e-100	338.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_3639983_1	1122182.KB903834_gene6099	7.987e-113	379.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4D8ES@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
DYD1_k127_3639983_11	595460.RRSWK_07188	1.078e-14	88.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	HEAT_2,Peptidase_M9,Peptidase_M9_N
DYD1_k127_3639983_10	387631.Asulf_00250	6.889e-15	87.0	arCOG02911@1|root,arCOG02911@2157|Archaea	2157|Archaea	M	toxin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3639983_5	1385935.N836_29705	7.033e-92	315.0	COG4292@1|root,COG4292@2|Bacteria,1GBJ3@1117|Cyanobacteria,1HES6@1150|Oscillatoriales	1117|Cyanobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
DYD1_k127_3639983_15	1206730.BAGA01000109_gene5470	4.565e-07	60.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria,4G19N@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD1_k127_3639983_9	693661.Arcve_1430	1.882e-15	90.0	COG1470@1|root,COG1572@1|root,arCOG02081@2157|Archaea,arCOG02532@2157|Archaea	2157|Archaea	P	APHP domain protein	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	A2M_comp,Big_3_5,CARDB,CarboxypepD_reg,DUF3344,Inhibitor_I9,PKD,Peptidase_S8,Thiol-ester_cl
DYD1_k127_3639983_17	215803.DB30_5455	0.0003988	54.0	COG0823@1|root,COG5276@1|root,COG0823@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,438JI@68525|delta/epsilon subdivisions,2X3U7@28221|Deltaproteobacteria,2YX4C@29|Myxococcales	28221|Deltaproteobacteria	U	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,TIG
DYD1_k127_3639983_4	1480694.DC28_14125	8.431e-100	337.0	COG0136@1|root,COG0136@2|Bacteria,2J5ZP@203691|Spirochaetes	203691|Spirochaetes	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DYD1_k127_3639983_14	381764.Fnod_1282	5.33e-10	64.0	COG0527@1|root,COG0527@2|Bacteria,2GD4P@200918|Thermotogae	200918|Thermotogae	E	Belongs to the aspartokinase family	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
DYD1_k127_3696137_0	1122135.KB893134_gene3221	5.274e-52	189.0	2C2J5@1|root,315UG@2|Bacteria,1RHAH@1224|Proteobacteria,2U94W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF3576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3576
DYD1_k127_3696137_1	1535422.ND16A_3140	1.726e-14	75.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8
DYD1_k127_3701778_1	1121035.AUCH01000005_gene176	5.372e-11	66.0	COG4970@1|root,COG4970@2|Bacteria,1N8HW@1224|Proteobacteria,2VWJK@28216|Betaproteobacteria,2KXD5@206389|Rhodocyclales	206389|Rhodocyclales	NU	Tfp pilus assembly protein FimT	-	-	-	ko:K10926	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
DYD1_k127_3701778_0	583345.Mmol_1196	7.857e-35	139.0	COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,2VUKR@28216|Betaproteobacteria,2KNTY@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10924	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
DYD1_k127_377613_0	694429.Pyrfu_0111	4.626e-223	704.0	COG0464@1|root,arCOG01308@2157|Archaea,2XPPI@28889|Crenarchaeota	28889|Crenarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
DYD1_k127_377613_24	224308.BSU26720	1.824e-06	57.0	COG1522@1|root,COG1522@2|Bacteria,1V319@1239|Firmicutes,4HFNU@91061|Bacilli,1ZD2Z@1386|Bacillus	91061|Bacilli	K	helix_turn_helix ASNC type	bkdR	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
DYD1_k127_377613_19	1343740.M271_42210	6.656e-14	78.0	2DNI3@1|root,32XMY@2|Bacteria,2GT3Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_377613_9	460265.Mnod_2730	6.942e-52	190.0	COG4106@1|root,COG4106@2|Bacteria,1QWJU@1224|Proteobacteria,2TWZZ@28211|Alphaproteobacteria,1JX8V@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DYD1_k127_377613_12	1122247.C731_0225	5.564e-44	164.0	COG0784@1|root,COG0784@2|Bacteria,2IFH8@201174|Actinobacteria,238TX@1762|Mycobacteriaceae	201174|Actinobacteria	T	response regulator, receiver	rcp1	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
DYD1_k127_377613_8	926560.KE387027_gene1088	2.721e-62	239.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS_4
DYD1_k127_377613_16	1070774.J07HN4v3_01586	1.42e-26	122.0	COG0784@1|root,arCOG02333@2157|Archaea,2Y7XX@28890|Euryarchaeota,23UQ9@183963|Halobacteria	183963|Halobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
DYD1_k127_377613_4	673860.AciM339_0622	7.246e-105	354.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,3F2HI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	PFAM Aminotransferase class I and II	aspC2	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DYD1_k127_377613_2	593117.TGAM_1943	9.18e-139	458.0	COG0172@1|root,arCOG00403@2157|Archaea,2XTGA@28890|Euryarchaeota,243GJ@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DYD1_k127_377613_20	1459636.NTE_01286	1.493e-12	80.0	COG1522@1|root,arCOG01586@2157|Archaea,41T3N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_377613_21	1261545.MBE-HAL_0013	2.085e-12	79.0	COG0608@1|root,arCOG00427@2157|Archaea,2XT8Y@28890|Euryarchaeota,23S1D@183963|Halobacteria	183963|Halobacteria	L	COG0608 Single-stranded DNA-specific exonuclease	recJ1	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
DYD1_k127_377613_10	694440.JOMF01000007_gene904	1.106e-47	175.0	COG0184@1|root,arCOG04185@2157|Archaea,2XWKV@28890|Euryarchaeota,2N9S2@224756|Methanomicrobia	224756|Methanomicrobia	J	ribosomal protein S15	rps15	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
DYD1_k127_377613_23	1156844.KB891812_gene5055	1.528e-09	70.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2GJYH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
DYD1_k127_377613_11	673860.AciM339_1444	5.962e-45	171.0	COG1601@1|root,COG3269@1|root,arCOG01640@2157|Archaea,arCOG01641@2157|Archaea,2XTVZ@28890|Euryarchaeota,3F2N9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2b	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	TRAM,eIF-5_eIF-2B
DYD1_k127_377613_25	1236902.ANAS01000039_gene4396	0.0001622	51.0	COG1492@1|root,COG1492@2|Bacteria,2GJ1W@201174|Actinobacteria,4EHX5@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
DYD1_k127_377613_1	439481.Aboo_0791	1.849e-204	656.0	COG0504@1|root,arCOG00063@2157|Archaea,2XTR2@28890|Euryarchaeota,3F2HU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DYD1_k127_377613_22	452652.KSE_32100	8.091e-11	64.0	COG3813@1|root,COG3813@2|Bacteria,2GRIY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
DYD1_k127_377613_18	1499685.CCFJ01000056_gene180	4.233e-20	100.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,4HBJY@91061|Bacilli,1ZC36@1386|Bacillus	91061|Bacilli	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
DYD1_k127_377613_15	439481.Aboo_0952	7.873e-27	116.0	arCOG05517@1|root,arCOG05517@2157|Archaea,2Y72T@28890|Euryarchaeota,3F3AH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_377613_3	439481.Aboo_1521	5.064e-118	388.0	COG0087@1|root,arCOG04070@2157|Archaea,2XT9B@28890|Euryarchaeota,3F2H1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl3	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DYD1_k127_377613_7	795797.C497_03412	4.841e-63	224.0	COG0469@1|root,arCOG04071@2157|Archaea,2XTXX@28890|Euryarchaeota,23SFS@183963|Halobacteria	183963|Halobacteria	J	Forms part of the polypeptide exit tunnel	rpl4lp	-	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DYD1_k127_377613_17	673860.AciM339_1100	9.324e-22	97.0	COG0089@1|root,arCOG04072@2157|Archaea,2XYPG@28890|Euryarchaeota,3F2T9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome	rpl23	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DYD1_k127_377613_6	224325.AF_1922	1.449e-70	245.0	COG0090@1|root,arCOG04067@2157|Archaea,2XTCS@28890|Euryarchaeota,245UM@183980|Archaeoglobi	183980|Archaeoglobi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rpl2	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
DYD1_k127_377613_13	926690.KE386573_gene1301	7.922e-42	158.0	COG0185@1|root,arCOG04099@2157|Archaea,2XWI9@28890|Euryarchaeota,23V5E@183963|Halobacteria	183963|Halobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rps19p	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DYD1_k127_377613_14	304371.MCP_2225	1.964e-31	133.0	COG0091@1|root,arCOG04098@2157|Archaea,2XWGN@28890|Euryarchaeota,2N9UR@224756|Methanomicrobia	224756|Methanomicrobia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rpl22	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DYD1_k127_377613_5	439481.Aboo_1515	6.401e-71	246.0	COG0092@1|root,arCOG04097@2157|Archaea,2XTHR@28890|Euryarchaeota,3F2JC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S3	rps3	GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DYD1_k127_3806869_2	177437.HRM2_03260	4.813e-43	163.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2MIKK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DYD1_k127_3806869_0	639030.JHVA01000001_gene1356	9.791e-70	241.0	COG2514@1|root,COG2514@2|Bacteria,3Y4I7@57723|Acidobacteria,2JJ9F@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
DYD1_k127_3806869_3	1961.JOAK01000010_gene6735	7.345e-41	154.0	COG3415@1|root,COG3415@2|Bacteria,2I3BN@201174|Actinobacteria	201174|Actinobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
DYD1_k127_3806869_1	1297569.MESS2_1220011	7.637e-58	208.0	COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria,2UC92@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
DYD1_k127_3819092_4	222984.JNCS01000004_gene2572	6.249e-61	232.0	COG1506@1|root,arCOG01646@2157|Archaea,2Y7PF@28890|Euryarchaeota,23UFR@183963|Halobacteria	183963|Halobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S15,Peptidase_S9
DYD1_k127_3819092_3	292459.STH1571	5.642e-134	441.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_3819092_0	439481.Aboo_0742	3.905e-191	618.0	COG1389@1|root,arCOG01165@2157|Archaea,2XTZQ@28890|Euryarchaeota,3F2EU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
DYD1_k127_3819092_1	439481.Aboo_0743	2.752e-159	510.0	COG1697@1|root,arCOG04143@2157|Archaea,2XTNQ@28890|Euryarchaeota,3F2HT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
DYD1_k127_3819092_9	387631.Asulf_02010	4.169e-08	56.0	COG1697@1|root,arCOG04143@2157|Archaea,2XTNQ@28890|Euryarchaeota,245RQ@183980|Archaeoglobi	183980|Archaeoglobi	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
DYD1_k127_3819092_7	671143.DAMO_0955	2.74e-20	104.0	293FI@1|root,2ZQXY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3819092_2	1094980.Mpsy_1495	1.266e-136	447.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,2N926@224756|Methanomicrobia	224756|Methanomicrobia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin,tRNA_deacylase
DYD1_k127_3819092_8	292415.Tbd_0859	7.71e-14	76.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,2VVRU@28216|Betaproteobacteria,1KTEJ@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
DYD1_k127_3819092_6	1227497.C491_15532	2.414e-42	178.0	arCOG11394@1|root,arCOG11394@2157|Archaea,2XU8U@28890|Euryarchaeota,23UIW@183963|Halobacteria	183963|Halobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DYD1_k127_3819092_5	1183377.Py04_0060	2.541e-43	164.0	COG0250@1|root,arCOG01920@2157|Archaea,2XWGQ@28890|Euryarchaeota,2441S@183968|Thermococci	183968|Thermococci	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
DYD1_k127_3828867_7	1297742.A176_07673	3.409e-14	85.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_3828867_0	1157632.AQWQ01000007_gene3797	4.582e-84	290.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DYD1_k127_3828867_2	1385514.N782_17950	1.208e-33	139.0	COG0842@1|root,COG0842@2|Bacteria,1U68B@1239|Firmicutes,4HFC9@91061|Bacilli,2Y9KU@289201|Pontibacillus	91061|Bacilli	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DYD1_k127_3828867_6	671065.MetMK1DRAFT_00019380	6.549e-15	82.0	COG1733@1|root,arCOG01057@2157|Archaea,2XSCC@28889|Crenarchaeota	28889|Crenarchaeota	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_3828867_8	635013.TherJR_0589	6.706e-11	70.0	COG2906@1|root,COG2906@2|Bacteria,1V246@1239|Firmicutes,25DRN@186801|Clostridia,262G7@186807|Peptococcaceae	186801|Clostridia	P	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
DYD1_k127_3828867_9	493475.GARC_2538	1.334e-06	57.0	2CCQM@1|root,347SS@2|Bacteria,1P2U8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3828867_1	1027273.GZ77_24950	1.298e-48	182.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1S6AG@1236|Gammaproteobacteria,1XK4B@135619|Oceanospirillales	135619|Oceanospirillales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
DYD1_k127_3828867_4	1158756.AQXQ01000007_gene365	2.749e-25	115.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DYD1_k127_3888_26	1266909.AUAG01000006_gene2475	1.132e-09	60.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,1RSNF@1236|Gammaproteobacteria,1X0P9@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
DYD1_k127_3888_12	518766.Rmar_0348	5.262e-29	123.0	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
DYD1_k127_3888_0	1236689.MMALV_11800	2.308e-137	462.0	COG1793@1|root,arCOG01347@2157|Archaea,2XTCK@28890|Euryarchaeota,3F2GX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
DYD1_k127_3888_15	1281779.H009_15346	3.718e-24	104.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,4BGBZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
DYD1_k127_3888_5	1227497.C491_13292	3.871e-63	231.0	COG3639@1|root,arCOG00173@2157|Archaea	2157|Archaea	P	COG3639 ABC-type phosphate phosphonate transport system, permease component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
DYD1_k127_3888_8	1238186.AOCN01000009_gene1574	7.338e-38	151.0	COG3638@1|root,COG3638@2|Bacteria,2GK02@201174|Actinobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
DYD1_k127_3888_24	571166.KI421509_gene4310	1.546e-11	77.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_3888_7	1536772.R70723_25960	1.462e-41	163.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,26X4A@186822|Paenibacillaceae	91061|Bacilli	D	Maf-like protein	maf	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
DYD1_k127_3888_3	1280681.AUJZ01000023_gene112	7.063e-66	237.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,4BWTZ@830|Butyrivibrio	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
DYD1_k127_3888_23	368407.Memar_0091	9.969e-12	79.0	COG3398@1|root,arCOG02611@2157|Archaea	2157|Archaea	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_3888_11	439481.Aboo_0658	1.936e-32	132.0	COG0720@1|root,arCOG02172@2157|Archaea,2XXFY@28890|Euryarchaeota,3F2RI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DYD1_k127_3888_1	673860.AciM339_0378	1.3e-78	272.0	COG0603@1|root,arCOG00039@2157|Archaea,2XTS7@28890|Euryarchaeota,3F2JU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
DYD1_k127_3888_13	1283300.ATXB01000002_gene2564	2.929e-25	116.0	COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,1S5RT@1236|Gammaproteobacteria,1XFNH@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
DYD1_k127_3888_20	1094980.Mpsy_1395	8.72e-17	92.0	COG1989@1|root,arCOG02298@2157|Archaea,2XUQP@28890|Euryarchaeota,2N9XX@224756|Methanomicrobia	224756|Methanomicrobia	N	Peptidase A24A, prepilin type IV	-	-	3.4.23.52	ko:K07991	-	-	-	-	ko00000,ko01000,ko01002,ko02035,ko02044	-	-	-	Arc_PepC_II,Peptidase_A24
DYD1_k127_3888_22	469382.Hbor_22970	4.753e-13	72.0	COG1400@1|root,arCOG01217@2157|Archaea,2XYV0@28890|Euryarchaeota,23WWX@183963|Halobacteria	183963|Halobacteria	J	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP	srp19	-	-	ko:K03105	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.7,3.A.5.9	-	-	SRP19
DYD1_k127_3888_9	1220534.B655_2348	5.429e-35	139.0	COG2007@1|root,arCOG04154@2157|Archaea,2XYXX@28890|Euryarchaeota,23P4U@183925|Methanobacteria	183925|Methanobacteria	J	Ribosomal protein S8e	rps8e	-	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
DYD1_k127_3888_14	1122622.ATWJ01000014_gene298	2.396e-24	109.0	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria,4FGZP@85021|Intrasporangiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DYD1_k127_3888_2	673860.AciM339_0266	1.78e-71	252.0	COG1235@1|root,arCOG00499@2157|Archaea,2XT48@28890|Euryarchaeota,3F2JB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DYD1_k127_3888_25	1137281.D778_00680	5.874e-11	74.0	COG2234@1|root,COG2234@2|Bacteria,4NJCD@976|Bacteroidetes,1IIII@117743|Flavobacteriia	976|Bacteroidetes	S	Leucyl aminopeptidase	-	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
DYD1_k127_3888_6	344747.PM8797T_15326	8.552e-49	189.0	arCOG08211@1|root,2ZBM3@2|Bacteria,2IZ2K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3888_21	273677.BW34_02757	4.083e-16	89.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4FKE9@85023|Microbacteriaceae	201174|Actinobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
DYD1_k127_3888_27	1229172.JQFA01000002_gene4587	2.994e-07	62.0	COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7IX@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DYD1_k127_3888_16	935557.ATYB01000014_gene2545	2.945e-22	111.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,4B7TU@82115|Rhizobiaceae	28211|Alphaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
DYD1_k127_3888_10	395961.Cyan7425_1508	2.028e-34	141.0	COG0406@1|root,COG0406@2|Bacteria,1G1TS@1117|Cyanobacteria,3KG37@43988|Cyanothece	1117|Cyanobacteria	G	Belongs to the phosphoglycerate mutase family	gpmB	-	3.1.3.3	ko:K22305	ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130	-	R00582	RC00017	ko00000,ko00001,ko01000	-	-	-	His_Phos_1
DYD1_k127_3888_17	1047013.AQSP01000138_gene1027	4.48e-21	107.0	2E9DF@1|root,333M0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_3888_4	754436.JCM19237_5282	7.367e-66	232.0	COG4912@1|root,COG4912@2|Bacteria,1QJE3@1224|Proteobacteria,1THDC@1236|Gammaproteobacteria,1XX53@135623|Vibrionales	135623|Vibrionales	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
DYD1_k127_3888_19	1237500.ANBA01000001_gene5074	2.349e-19	102.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4EI3T@85012|Streptosporangiales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_3897131_3	1318628.MARLIPOL_15000	6.269e-70	259.0	COG5563@1|root,COG5563@2|Bacteria,1QZID@1224|Proteobacteria,1T612@1236|Gammaproteobacteria,46DF6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929
DYD1_k127_3897131_2	1459636.NTE_02159	5.935e-72	252.0	COG0788@1|root,arCOG02826@2157|Archaea,41S78@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Formyl transferase	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT_6,Formyl_trans_N
DYD1_k127_3897131_1	40571.JOEA01000004_gene6302	2.743e-76	284.0	COG1404@1|root,COG1404@2|Bacteria,2I9U6@201174|Actinobacteria,4E1MY@85010|Pseudonocardiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
DYD1_k127_3897131_8	1380390.JIAT01000010_gene4906	2.22e-33	142.0	COG0491@1|root,COG0491@2|Bacteria,2HGYI@201174|Actinobacteria,4CQY2@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DYD1_k127_3897131_9	1196323.ALKF01000171_gene714	4.932e-27	119.0	COG3000@1|root,COG3000@2|Bacteria,1V2XN@1239|Firmicutes,4HFS5@91061|Bacilli,26X5T@186822|Paenibacillaceae	91061|Bacilli	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
DYD1_k127_3897131_13	1122611.KB903944_gene1149	1.588e-07	63.0	COG1083@1|root,COG1778@1|root,COG2089@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria,COG2089@2|Bacteria,2GJC9@201174|Actinobacteria,4EHFD@85012|Streptosporangiales	201174|Actinobacteria	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,NeuB
DYD1_k127_3897131_10	253839.SSNG_04309	5.445e-26	119.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DYD1_k127_3897131_6	765869.BDW_09805	5.834e-43	174.0	COG0204@1|root,COG0204@2|Bacteria,1N01J@1224|Proteobacteria,42UM7@68525|delta/epsilon subdivisions,2MURH@213481|Bdellovibrionales,2WQN9@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DYD1_k127_3897131_5	936550.HMPREF1492_0645	7.644e-52	210.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4CUAS@84998|Coriobacteriia	84998|Coriobacteriia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
DYD1_k127_3897131_7	926550.CLDAP_16300	1.113e-41	160.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
DYD1_k127_3897131_4	373903.Hore_04680	7.182e-58	212.0	COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,24AIH@186801|Clostridia	186801|Clostridia	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
DYD1_k127_3897131_12	742766.HMPREF9455_02181	7.019e-15	88.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,2FQ2M@200643|Bacteroidia,22XAT@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DYD1_k127_3897131_0	644966.Tmar_0598	9.105e-106	355.0	COG0665@1|root,COG0665@2|Bacteria,1TRYK@1239|Firmicutes	1239|Firmicutes	E	COG0665 Glycine D-amino acid oxidases (deaminating)	solA	-	1.5.3.1	ko:K00301,ko:K02846	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
DYD1_k127_3897131_11	1230457.C476_10542	1.737e-15	77.0	COG4799@1|root,arCOG02705@2157|Archaea,2XUNE@28890|Euryarchaeota,23U1N@183963|Halobacteria	183963|Halobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB1	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
DYD1_k127_3959009_6	459349.CLOAM0275	8.867e-22	111.0	COG1413@1|root,COG1413@2|Bacteria,2NQWQ@2323|unclassified Bacteria	2|Bacteria	C	lyase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
DYD1_k127_3959009_2	404589.Anae109_2337	2.12e-68	245.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DYD1_k127_3959009_5	290397.Adeh_2654	3.948e-42	166.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DYD1_k127_3959009_1	1033743.CAES01000109_gene3356	5.757e-76	278.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,26S2W@186822|Paenibacillaceae	91061|Bacilli	EH	Anthranilate synthase	pabB	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DYD1_k127_3959009_3	869210.Marky_0288	1.544e-58	221.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
DYD1_k127_3959009_4	867903.ThesuDRAFT_01448	3.986e-49	184.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3WCM0@538999|Clostridiales incertae sedis	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
DYD1_k127_3959009_0	1158338.JNLJ01000001_gene372	3.198e-151	494.0	COG0138@1|root,COG0138@2|Bacteria,2G3VH@200783|Aquificae	200783|Aquificae	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
DYD1_k127_4000835_2	1382306.JNIM01000001_gene2853	2.128e-188	608.0	COG2766@1|root,COG2766@2|Bacteria,2G65T@200795|Chloroflexi	200795|Chloroflexi	T	PrkA AAA domain protein	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
DYD1_k127_4000835_9	269797.Mbar_A2010	1.41e-20	104.0	COG0671@1|root,arCOG03951@2157|Archaea,2Y0A1@28890|Euryarchaeota,2NAVS@224756|Methanomicrobia	224756|Methanomicrobia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
DYD1_k127_4000835_0	1313301.AUGC01000005_gene328	1.615e-263	840.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DYD1_k127_4000835_1	1293047.CBMA010000054_gene3437	1.025e-250	791.0	COG0187@1|root,arCOG04371@2157|Archaea,2XSVX@28890|Euryarchaeota,23THF@183963|Halobacteria	183963|Halobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
DYD1_k127_4000835_10	368407.Memar_0273	2.446e-15	84.0	COG1439@1|root,arCOG00721@2157|Archaea,2XWH2@28890|Euryarchaeota,2NA00@224756|Methanomicrobia	224756|Methanomicrobia	V	PIN domain of ribonuclease	-	-	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
DYD1_k127_4000835_11	1236689.MMALV_02530	0.0002551	49.0	arCOG06958@1|root,arCOG06958@2157|Archaea,2Y41U@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4000835_6	391625.PPSIR1_32682	3.245e-35	145.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2X6EZ@28221|Deltaproteobacteria,2YWI8@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DYD1_k127_4000835_8	562970.Btus_1809	9.044e-29	123.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli,278IP@186823|Alicyclobacillaceae	91061|Bacilli	S	CoA binding domain	yneT	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
DYD1_k127_4000835_4	378806.STAUR_8131	5.726e-69	251.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WM87@28221|Deltaproteobacteria,2YUDN@29|Myxococcales	28221|Deltaproteobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
DYD1_k127_4000835_5	981369.JQMJ01000004_gene4665	7.867e-55	208.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	yugF	GO:0003674,GO:0003824,GO:0016787	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DYD1_k127_4000835_3	573063.Metin_0455	7.545e-94	328.0	COG0119@1|root,arCOG02092@2157|Archaea,2XSZJ@28890|Euryarchaeota,23QBT@183939|Methanococci	183939|Methanococci	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
DYD1_k127_4000835_7	439481.Aboo_0129	2.636e-31	128.0	COG0065@1|root,arCOG01698@2157|Archaea,2XTWH@28890|Euryarchaeota,3F31B@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.114,4.2.1.33,4.2.1.35	ko:K01703,ko:K16792	ko00290,ko00300,ko00660,ko00680,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00680,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00432,M00433,M00535,M00608	R03444,R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R09720,R10170,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DYD1_k127_4018074_0	1267535.KB906767_gene1307	7.059e-116	377.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria,2JISM@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DYD1_k127_4018074_1	1340493.JNIF01000004_gene564	7.177e-115	380.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
DYD1_k127_4071030_0	1226994.AMZB01000079_gene94	1.773e-08	60.0	COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1MWNN@1224|Proteobacteria,1RR74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	tail collar domain protein	H	-	-	-	-	-	-	-	-	-	-	-	Collar,DUF3751,Phage_fiber_2
DYD1_k127_4171329_3	667014.Thein_1365	1.16e-108	366.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	int	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
DYD1_k127_4171329_4	1242864.D187_005380	5.976e-107	362.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2Z06Y@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DYD1_k127_4171329_0	1457250.BBMO01000001_gene1351	5.206e-136	441.0	arCOG06187@1|root,arCOG06187@2157|Archaea,2XTSP@28890|Euryarchaeota,23S9E@183963|Halobacteria	183963|Halobacteria	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4171329_8	268739.Nmlp_1061	1.098e-06	61.0	arCOG02827@1|root,arCOG02827@2157|Archaea,2XU8M@28890|Euryarchaeota,23TAY@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF1508)	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4171329_7	1522072.IL54_3285	2.832e-12	76.0	COG2105@1|root,COG2105@2|Bacteria,1N80E@1224|Proteobacteria,2U5YU@28211|Alphaproteobacteria,2K78W@204457|Sphingomonadales	204457|Sphingomonadales	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
DYD1_k127_4171329_5	867903.ThesuDRAFT_01563	5.705e-52	191.0	COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,24FRV@186801|Clostridia	186801|Clostridia	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
DYD1_k127_4171329_9	926690.KE386573_gene1370	0.0007211	51.0	arCOG01744@1|root,arCOG01744@2157|Archaea,2XX9X@28890|Euryarchaeota,23VPY@183963|Halobacteria	183963|Halobacteria	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
DYD1_k127_4171329_2	448385.sce1569	8.016e-109	368.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria,2YU5E@29|Myxococcales	28221|Deltaproteobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DYD1_k127_4171329_1	290397.Adeh_1826	2.645e-124	406.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2YTX4@29|Myxococcales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DYD1_k127_4171329_6	883126.HMPREF9710_04737	2.917e-18	87.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VNZH@28216|Betaproteobacteria,477XG@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Dehydrogenase E1 component	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
DYD1_k127_4191379_0	1121033.AUCF01000002_gene556	5.151e-116	377.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,2JQA4@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrd	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
DYD1_k127_4203389_1	443144.GM21_3540	0.0001503	54.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DYD1_k127_4203389_0	1396141.BATP01000003_gene4975	4.449e-05	52.0	COG1361@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,46WJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
DYD1_k127_420426_1	589924.Ferp_2177	1.592e-84	285.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,2462Q@183980|Archaeoglobi	183980|Archaeoglobi	O	AAA family ATPase, CDC48 subfamily	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
DYD1_k127_420426_3	105559.Nwat_2961	3.443e-27	115.0	COG3631@1|root,COG3631@2|Bacteria,1RD0K@1224|Proteobacteria,1S8NU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
DYD1_k127_420426_6	1347369.CCAD010000012_gene2402	2.482e-08	61.0	COG5649@1|root,COG5649@2|Bacteria,1VF35@1239|Firmicutes,4HQN0@91061|Bacilli,1ZIJ5@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DYD1_k127_420426_4	587753.EY04_25835	1.705e-09	68.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
DYD1_k127_420426_7	1402135.SUH3_18165	1.736e-07	60.0	COG1733@1|root,COG1733@2|Bacteria,1RF0R@1224|Proteobacteria,2U1VF@28211|Alphaproteobacteria,3ZXG5@60136|Sulfitobacter	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	MA20_07320	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_420426_5	2074.JNYD01000009_gene5200	2.123e-09	70.0	2C75R@1|root,2ZCK5@2|Bacteria,2IBVD@201174|Actinobacteria,4E8JR@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_420426_0	697281.Mahau_0316	8.745e-171	548.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DYD1_k127_420426_2	469371.Tbis_1584	1.187e-62	227.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4EA0B@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DYD1_k127_4208182_0	1121272.KB903290_gene4747	6.188e-69	241.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4208217_0	1121272.KB903290_gene4747	2.944e-64	236.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4223745_0	309801.trd_0141	5.153e-08	64.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Metallophos,fn3
DYD1_k127_4310157_41	709986.Deima_0439	5.1e-07	59.0	COG2132@1|root,COG3794@1|root,COG2132@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,DUF4396
DYD1_k127_4310157_47	1227484.C471_09165	3.332e-05	56.0	COG2132@1|root,COG2133@1|root,arCOG07560@1|root,arCOG02796@2157|Archaea,arCOG03914@2157|Archaea,arCOG07560@2157|Archaea,2Y82S@28890|Euryarchaeota,2413S@183963|Halobacteria	2157|Archaea	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	CBM_6,Copper-bind,Cu-oxidase_2,Cu-oxidase_3,GH97_C,GH97_N,GSDH,Glucodextran_C,Glyco_hydro_97,Laminin_G_3,Malectin,NPCBM_assoc,PKD
DYD1_k127_4310157_46	1114856.C496_03528	3.332e-05	56.0	arCOG11135@1|root,arCOG10367@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD1_k127_4310157_50	1121945.ATXS01000003_gene1402	0.000369	46.0	COG3413@1|root,arCOG02272@2157|Archaea,2Y7SJ@28890|Euryarchaeota,240WI@183963|Halobacteria	183963|Halobacteria	K	Bacterio-opsin activator HTH domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_10
DYD1_k127_4310157_14	579137.Metvu_0558	1.256e-68	238.0	COG1632@1|root,arCOG04209@2157|Archaea,2XTJJ@28890|Euryarchaeota,23Q5E@183939|Methanococci	183939|Methanococci	J	Belongs to the eukaryotic ribosomal protein eL15 family	rpl15e	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
DYD1_k127_4310157_18	1449346.JQMO01000002_gene904	1.371e-56	202.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria,2M3WY@2063|Kitasatospora	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
DYD1_k127_4310157_3	1178537.BA1_17235	1.705e-157	511.0	COG0388@1|root,COG3153@1|root,COG0388@2|Bacteria,COG3153@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus	91061|Bacilli	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yhcX	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
DYD1_k127_4310157_38	673860.AciM339_0905	3.471e-09	62.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y747@28890|Euryarchaeota,3F3DB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD1_k127_4310157_40	272943.RSP_3263	4.711e-08	61.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2U6DH@28211|Alphaproteobacteria,1FCU8@1060|Rhodobacter	28211|Alphaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,CusF_Ec
DYD1_k127_4310157_17	926554.KI912636_gene3056	1.241e-56	214.0	COG2132@1|root,COG3794@1|root,COG2132@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,DUF4396
DYD1_k127_4310157_9	1234364.AMSF01000002_gene2325	5.025e-92	323.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,1MV74@1224|Proteobacteria,1RXZF@1236|Gammaproteobacteria,1X9Y2@135614|Xanthomonadales	135614|Xanthomonadales	CQ	nitrite reductase	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
DYD1_k127_4310157_48	1122599.AUGR01000030_gene497	5.745e-05	53.0	COG5592@1|root,COG5592@2|Bacteria,1PVY7@1224|Proteobacteria,1T6FR@1236|Gammaproteobacteria,1XQKB@135619|Oceanospirillales	135619|Oceanospirillales	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4310157_28	1122622.ATWJ01000010_gene1431	6.644e-32	135.0	2F548@1|root,33XRC@2|Bacteria,2H5BG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4310157_43	290397.Adeh_1448	2.167e-06	58.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD1_k127_4310157_30	667632.KB890209_gene5505	2.089e-26	126.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2VNCK@28216|Betaproteobacteria,1K35S@119060|Burkholderiaceae	28216|Betaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281,ko:K06978	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
DYD1_k127_4310157_37	1120933.ATUY01000003_gene331	2.635e-11	72.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D52E@85005|Actinomycetales	201174|Actinobacteria	T	FHA domain protein	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
DYD1_k127_4310157_26	404589.Anae109_1433	4.149e-33	147.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,43AQI@68525|delta/epsilon subdivisions,2X64F@28221|Deltaproteobacteria	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
DYD1_k127_4310157_1	187272.Mlg_0261	7.52e-257	823.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales	135613|Chromatiales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
DYD1_k127_4310157_29	1278073.MYSTI_04410	1.779e-27	134.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36,Peptidase_M6
DYD1_k127_4310157_27	673860.AciM339_0730	2.342e-32	150.0	COG4934@1|root,arCOG05978@1|root,arCOG03669@2157|Archaea,arCOG05978@2157|Archaea,2Y7X2@28890|Euryarchaeota,3F38G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ,fn3
DYD1_k127_4310157_35	935845.JADQ01000007_gene1675	4.498e-13	86.0	COG4733@1|root,COG4733@2|Bacteria,1V0X5@1239|Firmicutes,4HDRK@91061|Bacilli,26VBX@186822|Paenibacillaceae	91061|Bacilli	DZ	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like
DYD1_k127_4310157_24	1128421.JAGA01000003_gene2766	9.224e-37	164.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_S8
DYD1_k127_4310157_52	224325.AF_1459	0.0008835	45.0	COG3432@1|root,arCOG01055@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	ko:K11924	-	-	-	-	ko00000,ko03000	-	-	-	HTH_45
DYD1_k127_4310157_19	1116232.AHBF01000077_gene8114	1.086e-55	210.0	COG1741@1|root,COG1741@2|Bacteria,2IA7X@201174|Actinobacteria	201174|Actinobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
DYD1_k127_4310157_36	1192868.CAIU01000007_gene697	5.724e-13	75.0	COG1733@1|root,COG1733@2|Bacteria,1PHU0@1224|Proteobacteria,2VAGZ@28211|Alphaproteobacteria,43PZA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_4310157_10	525903.Taci_1260	1.482e-81	289.0	COG0733@1|root,COG0733@2|Bacteria,3T9W5@508458|Synergistetes	508458|Synergistetes	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
DYD1_k127_4310157_34	263820.PTO0743	2.537e-15	82.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0G0@28890|Euryarchaeota,241VK@183967|Thermoplasmata	183967|Thermoplasmata	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
DYD1_k127_4310157_44	1300345.LF41_1319	8.385e-06	50.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
DYD1_k127_4310157_33	1094980.Mpsy_1797	6.517e-18	87.0	COG1745@1|root,arCOG02254@2157|Archaea,2XZ09@28890|Euryarchaeota,2NA4W@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0058	-	-	-	-	-	-	-	-	-	-	-	-	UPF0058
DYD1_k127_4310157_42	452637.Oter_3487	8.618e-07	59.0	COG0631@1|root,COG0631@2|Bacteria,46ZFD@74201|Verrucomicrobia,3K84Y@414999|Opitutae	414999|Opitutae	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
DYD1_k127_4310157_6	304371.MCP_0113	5.151e-102	360.0	COG0358@1|root,arCOG04281@2157|Archaea,2XTHB@28890|Euryarchaeota,2N98U@224756|Methanomicrobia	224756|Methanomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
DYD1_k127_4310157_12	485914.Hmuk_0021	1.881e-73	255.0	COG0717@1|root,arCOG04048@2157|Archaea,2XTSH@28890|Euryarchaeota,23S4X@183963|Halobacteria	183963|Halobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
DYD1_k127_4310157_8	673860.AciM339_0290	2.483e-92	313.0	COG1469@1|root,arCOG04301@2157|Archaea,2XT11@28890|Euryarchaeota,3F2JX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin	mptA	GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682	3.5.4.39	ko:K17488	ko00790,map00790	-	R10348	RC02504,RC03131	ko00000,ko00001,ko01000	-	-	-	GCHY-1
DYD1_k127_4310157_51	1399115.U719_11615	0.0008132	49.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
DYD1_k127_4310157_4	383372.Rcas_0809	8.23e-149	497.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi,37534@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
DYD1_k127_4310157_21	662479.C440_12659	3.757e-54	201.0	COG0189@1|root,arCOG01589@2157|Archaea,2XXK5@28890|Euryarchaeota,23VQP@183963|Halobacteria	183963|Halobacteria	H	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
DYD1_k127_4310157_16	1236689.MMALV_10400	4.347e-60	222.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,3F2IJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22
DYD1_k127_4310157_32	304371.MCP_0278	1.188e-18	89.0	COG2835@1|root,arCOG04124@2157|Archaea,2XZRS@28890|Euryarchaeota,2NA4S@224756|Methanomicrobia	224756|Methanomicrobia	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
DYD1_k127_4310157_23	1094980.Mpsy_0913	3.703e-38	154.0	COG1407@1|root,arCOG01150@2157|Archaea,2XU3W@28890|Euryarchaeota,2N9DU@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM metallophosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
DYD1_k127_4310157_2	1054217.TALC_01538	3.886e-231	751.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,241ID@183967|Thermoplasmata	183967|Thermoplasmata	L	helicase superfamily c-terminal domain	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DYD1_k127_4310157_5	1041930.Mtc_1564	1.551e-139	455.0	COG1222@1|root,arCOG01306@2157|Archaea,2XTB6@28890|Euryarchaeota,2N92K@224756|Methanomicrobia	224756|Methanomicrobia	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates	pan	-	-	ko:K03420	ko03050,map03050	M00343	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA
DYD1_k127_4310157_31	439481.Aboo_1419	9.062e-25	115.0	COG1813@1|root,arCOG01863@2157|Archaea,2XXND@28890|Euryarchaeota,3F2TJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
DYD1_k127_4310157_13	644281.MFS40622_0392	3.073e-71	251.0	COG0024@1|root,arCOG01001@2157|Archaea,2XT8G@28890|Euryarchaeota,23Q49@183939|Methanococci	183939|Methanococci	J	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DYD1_k127_4310157_25	391623.TERMP_00409	6.357e-35	145.0	COG0101@1|root,arCOG04449@2157|Archaea,2XTH5@28890|Euryarchaeota,242SP@183968|Thermococci	183968|Thermococci	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
DYD1_k127_4310157_7	1121938.AUDY01000008_gene1501	1.441e-100	342.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3NEER@45667|Halobacillus	91061|Bacilli	EF	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15510	CPSase_sm_chain,GATase
DYD1_k127_4310157_0	1236689.MMALV_05010	0.0	1262.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2374	CPSase_L_D2,CPSase_L_D3,MGS
DYD1_k127_4310157_39	1210884.HG799462_gene8052	2.621e-08	66.0	COG1277@1|root,COG1277@2|Bacteria,2J3V9@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4310157_11	1210884.HG799462_gene8051	1.481e-76	270.0	COG1131@1|root,COG1131@2|Bacteria,2IZF2@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DYD1_k127_4310157_15	1210884.HG799462_gene8049	3.182e-67	244.0	COG1131@1|root,COG1131@2|Bacteria,2IZ5V@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_4310157_45	1227454.C446_05800	1.11e-05	58.0	COG3398@1|root,arCOG02611@2157|Archaea,2XV4M@28890|Euryarchaeota,23V38@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD1_k127_4310157_49	485918.Cpin_3133	0.0001134	54.0	COG4774@1|root,COG4774@2|Bacteria,4PKB5@976|Bacteroidetes	976|Bacteroidetes	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD1_k127_4310157_22	589924.Ferp_0848	9.62e-43	162.0	COG0099@1|root,arCOG01722@2157|Archaea,2XWHE@28890|Euryarchaeota,24709@183980|Archaeoglobi	183980|Archaeoglobi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DYD1_k127_4310157_20	439481.Aboo_1397	2.872e-55	199.0	COG0522@1|root,arCOG04239@2157|Archaea,2XXYX@28890|Euryarchaeota,3F2KM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DYD1_k127_4379224_1	649831.L083_3335	8.272e-05	52.0	COG4733@1|root,COG4733@2|Bacteria,2I61V@201174|Actinobacteria,4DJUW@85008|Micromonosporales	201174|Actinobacteria	MU	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DYD1_k127_4379224_2	649831.L083_3335	0.0002588	50.0	COG4733@1|root,COG4733@2|Bacteria,2I61V@201174|Actinobacteria,4DJUW@85008|Micromonosporales	201174|Actinobacteria	MU	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DYD1_k127_4379224_3	65497.JODV01000013_gene2202	0.000838	55.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4E1CS@85010|Pseudonocardiales	201174|Actinobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,ThuA
DYD1_k127_4379224_0	926562.Oweho_2792	1.046e-05	62.0	COG1409@1|root,COG1409@2|Bacteria,4NEQ8@976|Bacteroidetes,1I0MD@117743|Flavobacteriia	976|Bacteroidetes	S	Ser Thr phosphatase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DYD1_k127_4426955_0	1545915.JROG01000001_gene392	4.748e-94	309.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,2K177@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DYD1_k127_4426955_2	298386.PBPRB1364	0.0003381	48.0	2AXZ3@1|root,31Q0K@2|Bacteria,1QMP6@1224|Proteobacteria,1TJYT@1236|Gammaproteobacteria,1Y1V6@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4426955_1	1297570.MESS4_560108	4.076e-08	57.0	2DGHW@1|root,2ZW1T@2|Bacteria,1P867@1224|Proteobacteria,2UWAZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4509395_0	1121946.AUAX01000007_gene2746	2.522e-06	55.0	COG5434@1|root,COG5434@2|Bacteria,2II7D@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
DYD1_k127_4638145_2	649831.L083_3335	0.0001442	51.0	COG4733@1|root,COG4733@2|Bacteria,2I61V@201174|Actinobacteria,4DJUW@85008|Micromonosporales	201174|Actinobacteria	MU	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
DYD1_k127_4638145_0	697284.ERIC2_c25910	0.0	1350.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,26T6P@186822|Paenibacillaceae	91061|Bacilli	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
DYD1_k127_4638145_1	351160.RRC456	4.752e-49	192.0	COG3263@1|root,arCOG01962@2157|Archaea	2157|Archaea	P	Sodium hydrogen exchanger	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger
DYD1_k127_4693515_4	543632.JOJL01000011_gene7020	4.546e-10	73.0	29XQA@1|root,30JFY@2|Bacteria,2GRBA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4693515_6	59894.ENSFALP00000005675	0.0008268	51.0	KOG1721@1|root,KOG1721@2759|Eukaryota,38E9Z@33154|Opisthokonta,3BBQN@33208|Metazoa,3CZGS@33213|Bilateria,486I2@7711|Chordata,48YBR@7742|Vertebrata,4GP94@8782|Aves	33208|Metazoa	K	Zinc finger protein PLAGL2	PLAGL2	GO:0000981,GO:0000982,GO:0001077,GO:0001228,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006725,GO:0006807,GO:0006915,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0012501,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032501,GO:0032774,GO:0034377,GO:0034378,GO:0034641,GO:0034645,GO:0034654,GO:0043062,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065005,GO:0065007,GO:0071704,GO:0071825,GO:0071827,GO:0071840,GO:0080090,GO:0090304,GO:0097006,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K19484,ko:K19486	-	-	-	-	ko00000,ko03000	-	-	-	zf-C2H2,zf-C2H2_4,zf-C2H2_6
DYD1_k127_4693515_3	913865.DOT_5669	7.413e-13	77.0	2E2AR@1|root,309HC@2|Bacteria,1VP2W@1239|Firmicutes,25DRK@186801|Clostridia	186801|Clostridia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4693515_5	1166018.FAES_3931	3.848e-07	59.0	2EQ06@1|root,340RM@2|Bacteria,4PQ0X@976|Bacteroidetes,47YT4@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4693515_2	1227349.C170_10390	3.816e-16	93.0	COG1643@1|root,COG1643@2|Bacteria,1TPET@1239|Firmicutes,4HE8W@91061|Bacilli,26U7B@186822|Paenibacillaceae	91061|Bacilli	L	ATP-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
DYD1_k127_4693515_0	1151061.CAJY01000041_gene653	1.979e-81	281.0	COG0863@1|root,COG0863@2|Bacteria,2I9DJ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DYD1_k127_4708462_41	395493.BegalDRAFT_2517	6.032e-06	54.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
DYD1_k127_4708462_7	1054217.TALC_01206	7.619e-91	318.0	COG0124@1|root,arCOG00404@2157|Archaea,2XSYX@28890|Euryarchaeota,241P5@183967|Thermoplasmata	183967|Thermoplasmata	J	histidyl-tRNA aminoacylation	hisS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DYD1_k127_4708462_1	192952.MM_0593	3.805e-158	507.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota,2N9HE@224756|Methanomicrobia	224756|Methanomicrobia	F	Protein of unknown function (DUF1246)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
DYD1_k127_4708462_26	42256.RradSPS_2550	2.11e-26	118.0	COG0212@1|root,COG0212@2|Bacteria	2|Bacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
DYD1_k127_4708462_42	1453505.JASY01000024_gene298	1.888e-05	56.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXSI@117743|Flavobacteriia,2NVDB@237|Flavobacterium	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD1_k127_4708462_6	323259.Mhun_2853	3.917e-104	351.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,2N9G1@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transferase
DYD1_k127_4708462_8	485914.Hmuk_1132	9.245e-81	293.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,23SSW@183963|Halobacteria	183963|Halobacteria	G	Belongs to the phosphohexose mutase family	-	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DYD1_k127_4708462_29	195522.BD01_1811	1.737e-19	104.0	COG1572@1|root,COG3889@1|root,arCOG02497@1|root,arCOG02499@1|root,arCOG02545@1|root,arCOG02554@1|root,arCOG03439@1|root,arCOG01672@2157|Archaea,arCOG02497@2157|Archaea,arCOG02499@2157|Archaea,arCOG02545@2157|Archaea,arCOG02554@2157|Archaea,arCOG03439@2157|Archaea,arCOG07086@2157|Archaea,2XU6I@28890|Euryarchaeota,245EQ@183968|Thermococci	183968|Thermococci	S	solute binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DYD1_k127_4708462_39	384616.Pisl_1082	8.635e-12	67.0	COG2126@1|root,arCOG04126@2157|Archaea	2157|Archaea	J	Binds to the 23S rRNA	rpl37e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02922	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37e
DYD1_k127_4708462_31	1236689.MMALV_13580	1.867e-17	84.0	COG1958@1|root,arCOG00998@2157|Archaea,2XZTF@28890|Euryarchaeota,3F2SB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	snRNP Sm proteins	lsm	GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
DYD1_k127_4708462_22	1054217.TALC_00459	3.666e-36	143.0	COG2016@1|root,arCOG00985@2157|Archaea,2XX1R@28890|Euryarchaeota,241XH@183967|Thermoplasmata	183967|Thermoplasmata	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	-	ko:K07575	-	-	-	-	ko00000	-	-	-	DUF1947,PUA
DYD1_k127_4708462_27	673860.AciM339_0306	6.114e-23	102.0	COG2450@1|root,arCOG02263@2157|Archaea,2XXYF@28890|Euryarchaeota,3F3BW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Pfam:DUF552	sepF	-	-	ko:K09152	-	-	-	-	ko00000	-	-	-	SepF
DYD1_k127_4708462_10	391625.PPSIR1_12873	4.552e-79	280.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,42PYC@68525|delta/epsilon subdivisions,2WMC4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DYD1_k127_4708462_15	673860.AciM339_0248	7.463e-70	252.0	COG1244@1|root,arCOG01360@2157|Archaea,2XT5Q@28890|Euryarchaeota,3F2I0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	Radical_SAM
DYD1_k127_4708462_14	1054217.TALC_01156	1.022e-74	275.0	COG1549@1|root,arCOG00990@2157|Archaea,2XT9W@28890|Euryarchaeota,241NM@183967|Thermoplasmata	183967|Thermoplasmata	J	PUA domain	-	-	2.6.1.97	ko:K07557	-	-	-	-	ko00000,ko01000	-	-	-	PUA
DYD1_k127_4708462_33	1183377.Py04_0996	2.242e-15	91.0	COG0457@1|root,COG0640@1|root,COG1672@1|root,arCOG01679@2157|Archaea,arCOG03045@2157|Archaea,arCOG03169@2157|Archaea,2Y1R2@28890|Euryarchaeota,242W9@183968|Thermococci	183968|Thermococci	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,TPR_8
DYD1_k127_4708462_13	266117.Rxyl_1272	1.176e-77	277.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CQH1@84995|Rubrobacteria	84995|Rubrobacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
DYD1_k127_4708462_5	349161.Dred_2912	5.886e-105	359.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,260IQ@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM potassium uptake protein, TrkH family	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DYD1_k127_4708462_11	479434.Sthe_1775	1.222e-78	273.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_4708462_16	298655.KI912266_gene2835	2.043e-69	269.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2ICGU@201174|Actinobacteria	201174|Actinobacteria	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
DYD1_k127_4708462_36	378806.STAUR_0240	1.314e-13	79.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,42V7W@68525|delta/epsilon subdivisions,2WPHM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_4708462_12	485913.Krac_10598	1.055e-77	271.0	COG1398@1|root,COG1398@2|Bacteria,2G88P@200795|Chloroflexi	200795|Chloroflexi	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
DYD1_k127_4708462_25	1330700.JQNC01000003_gene539	7.066e-29	128.0	COG0861@1|root,COG0861@2|Bacteria,1WIXE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
DYD1_k127_4708462_19	926554.KI912617_gene4840	2.994e-53	212.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DYD1_k127_4708462_38	502025.Hoch_1827	3.781e-12	76.0	COG0671@1|root,COG0671@2|Bacteria,1RDK3@1224|Proteobacteria,42TCF@68525|delta/epsilon subdivisions,2WPUS@28221|Deltaproteobacteria,2YVXS@29|Myxococcales	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DYD1_k127_4708462_4	224325.AF_0508	4.728e-128	421.0	COG0214@1|root,arCOG04075@2157|Archaea,2XSYK@28890|Euryarchaeota,2462G@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ,ThiG
DYD1_k127_4708462_35	479432.Sros_8167	1.01e-14	86.0	COG3733@1|root,COG3733@2|Bacteria,2GIVJ@201174|Actinobacteria,4EM1A@85012|Streptosporangiales	201174|Actinobacteria	Q	Copper amine oxidase, enzyme domain	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN3
DYD1_k127_4708462_43	479432.Sros_8166	0.000666	50.0	COG3733@1|root,COG3733@2|Bacteria,2H6M8@201174|Actinobacteria	201174|Actinobacteria	Q	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4708462_21	694429.Pyrfu_0049	1.032e-37	156.0	COG0618@1|root,arCOG01565@2157|Archaea,2XQUB@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
DYD1_k127_4708462_30	572546.Arcpr_1654	5.171e-18	89.0	COG1382@1|root,arCOG01342@2157|Archaea,2XX88@28890|Euryarchaeota,246EF@183980|Archaeoglobi	183980|Archaeoglobi	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
DYD1_k127_4708462_2	406327.Mevan_1059	3.641e-143	471.0	COG0595@1|root,arCOG00546@2157|Archaea,2XTBT@28890|Euryarchaeota,23Q9B@183939|Methanococci	183939|Methanococci	J	An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
DYD1_k127_4708462_23	1082931.KKY_2561	1.002e-34	147.0	COG2342@1|root,COG2342@2|Bacteria,1N2HD@1224|Proteobacteria,2UEA7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Glycoside-hydrolase family GH114	-	-	6.1.1.16	ko:K01884	ko00970,map00970	M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Glyco_hydro_114,HemolysinCabind
DYD1_k127_4708462_17	351160.RCIX1238	2.58e-65	228.0	COG2101@1|root,arCOG01764@2157|Archaea,2XTTR@28890|Euryarchaeota,2N9N0@224756|Methanomicrobia	224756|Methanomicrobia	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbpE	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DYD1_k127_4708462_44	673860.AciM339_0164	0.0006973	45.0	arCOG05368@1|root,arCOG05368@2157|Archaea,2Y1EG@28890|Euryarchaeota,3F2W6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4708462_28	1236689.MMALV_01560	1.457e-19	90.0	COG1758@1|root,arCOG01268@2157|Archaea,2XZSW@28890|Euryarchaeota,3F2TZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	2.7.7.6	ko:K03055	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb6
DYD1_k127_4708462_9	1054217.TALC_00169	5.013e-80	273.0	COG0052@1|root,arCOG04245@2157|Archaea,2XTHM@28890|Euryarchaeota,241MQ@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the universal ribosomal protein uS2 family	rps2	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DYD1_k127_4708462_0	351160.RCIX317	2.277e-237	756.0	COG3808@1|root,arCOG04949@2157|Archaea,2XTDB@28890|Euryarchaeota,2N98C@224756|Methanomicrobia	224756|Methanomicrobia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
DYD1_k127_4708462_18	1236689.MMALV_04370	9.081e-56	203.0	COG1095@1|root,arCOG00675@2157|Archaea,2XT6U@28890|Euryarchaeota,3F2MN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397	rpoE1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
DYD1_k127_4708462_40	368407.Memar_2243	1.306e-11	66.0	COG2093@1|root,arCOG04077@2157|Archaea,2Y0D6@28890|Euryarchaeota,2NA1J@224756|Methanomicrobia	224756|Methanomicrobia	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
DYD1_k127_4708462_34	391623.TERMP_02014	3.705e-15	85.0	COG1909@1|root,arCOG04076@2157|Archaea,2XXSG@28890|Euryarchaeota,2440N@183968|Thermococci	183968|Thermococci	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
DYD1_k127_4708462_32	931277.C448_01012	2.405e-16	82.0	COG2004@1|root,arCOG04182@2157|Archaea,2XXXB@28890|Euryarchaeota,23W6E@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eukaryotic ribosomal protein eS24 family	rps24e	-	-	ko:K02974	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S24e
DYD1_k127_4708462_37	1236689.MMALV_04410	3.039e-13	74.0	COG1998@1|root,arCOG04183@2157|Archaea,2XZZ0@28890|Euryarchaeota,3F2VM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
DYD1_k127_4708462_24	481448.Minf_1647	3.824e-33	130.0	2DBJQ@1|root,32TXM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_excise
DYD1_k127_4708462_3	983545.Glaag_1878	8.193e-130	432.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,464RP@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905	DALR_2,tRNA-synt_1e,tRNA-synt_1g
DYD1_k127_4708462_20	1157637.KB892124_gene866	5.034e-49	185.0	COG3576@1|root,COG3576@2|Bacteria,2GP9M@201174|Actinobacteria	201174|Actinobacteria	C	pyridoxamine 5-phosphate	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
DYD1_k127_4731997_0	671143.DAMO_2706	1.314e-161	518.0	COG1009@1|root,COG1009@2|Bacteria,2NNM8@2323|unclassified Bacteria	2|Bacteria	CP	NADH-quinone oxidoreductase chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
DYD1_k127_4740804_0	304371.MCP_1505	5.082e-31	133.0	COG1096@1|root,arCOG00676@2157|Archaea,2XYYA@28890|Euryarchaeota,2N9T0@224756|Methanomicrobia	224756|Methanomicrobia	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,EXOSC1
DYD1_k127_4740804_1	66874.JOFS01000049_gene3200	2e-25	122.0	2AQV1@1|root,31G37@2|Bacteria,2IEU1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DYD1_k127_4866201_0	616991.JPOO01000003_gene2290	9.488e-68	240.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
DYD1_k127_4866201_16	285514.JNWO01000025_gene353	0.0003726	52.0	COG1522@1|root,COG1522@2|Bacteria,2GN6I@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
DYD1_k127_4866201_4	634498.mru_0221	2.344e-29	132.0	COG3177@1|root,arCOG03110@2157|Archaea,2XUN8@28890|Euryarchaeota,23PGE@183925|Methanobacteria	183925|Methanobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
DYD1_k127_4866201_6	211114.JOEF01000014_gene4781	1.548e-24	115.0	COG5640@1|root,COG5640@2|Bacteria,2GN18@201174|Actinobacteria,4E49K@85010|Pseudonocardiales	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
DYD1_k127_4866201_1	700598.Niako_3435	3.346e-65	230.0	28H95@1|root,2Z7KY@2|Bacteria,4NG37@976|Bacteroidetes,1IPRY@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
DYD1_k127_4866201_7	1089544.KB912942_gene2377	1.106e-23	117.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4866201_12	1297570.MESS4_360101	1.199e-12	80.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,43MH7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_4866201_3	756499.Desde_2677	2.22e-34	137.0	COG0346@1|root,COG0346@2|Bacteria,1V6CB@1239|Firmicutes,25BFW@186801|Clostridia,265DN@186807|Peptococcaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
DYD1_k127_4866201_17	1207055.C100_06345	0.0007658	47.0	COG5470@1|root,COG5470@2|Bacteria,1N54U@1224|Proteobacteria,2UDJU@28211|Alphaproteobacteria,2K6HW@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
DYD1_k127_4866201_2	1416752.AYME01000008_gene3392	4.121e-41	166.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	2.7.1.89	ko:K07251	ko00730,ko01100,map00730,map01100	-	R02134	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	APH,Choline_kinase
DYD1_k127_4866201_8	547559.Nmag_1047	3.146e-22	110.0	COG0492@1|root,arCOG01296@2157|Archaea,2XU1T@28890|Euryarchaeota,23SNC@183963|Halobacteria	183963|Halobacteria	O	COG0492 Thioredoxin reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
DYD1_k127_4866201_9	756883.Halar_2133	4.973e-18	93.0	COG3413@1|root,arCOG02271@2157|Archaea	2157|Archaea	S	Bacterio-opsin activator HTH	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
DYD1_k127_4866201_11	401053.AciPR4_4073	4.329e-14	74.0	COG2070@1|root,COG2070@2|Bacteria,3Y41M@57723|Acidobacteria,2JHUD@204432|Acidobacteriia	204432|Acidobacteriia	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
DYD1_k127_4866201_15	717605.Theco_3887	2.902e-05	50.0	COG3677@1|root,COG3677@2|Bacteria,1V800@1239|Firmicutes,4IRED@91061|Bacilli,276R8@186822|Paenibacillaceae	91061|Bacilli	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_Tnp_IS1595
DYD1_k127_4866201_14	523841.HFX_0509	1.989e-06	54.0	COG3794@1|root,arCOG02917@2157|Archaea,2XXRT@28890|Euryarchaeota,23WFH@183963|Halobacteria	183963|Halobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD1_k127_4866201_13	1968.JOEV01000048_gene3437	1.451e-08	63.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
DYD1_k127_4866201_5	931277.C448_06745	3.975e-25	118.0	COG0704@1|root,arCOG00318@2157|Archaea,2XUA4@28890|Euryarchaeota,23S6Y@183963|Halobacteria	183963|Halobacteria	K	Phosphate uptake regulator	phoU1	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
DYD1_k127_4866201_10	335283.Neut_1406	8.979e-15	81.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2W03M@28216|Betaproteobacteria,374KI@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	Multicopper oxidase type 1	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
DYD1_k127_4872912_1	1408813.AYMG01000046_gene4793	8.07e-14	82.0	COG3210@1|root,COG3291@1|root,COG4935@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,1IRNR@117747|Sphingobacteriia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
DYD1_k127_4872912_0	926692.AZYG01000059_gene52	1.181e-22	115.0	COG1293@1|root,COG5283@1|root,COG1293@2|Bacteria,COG5283@2|Bacteria	2|Bacteria	K	actin binding	FbpA	-	3.1.21.3,3.2.1.170	ko:K01153,ko:K15524	-	-	-	-	ko00000,ko01000,ko02048	-	GH38	-	DUF814,FbpA,PhageMin_Tail
DYD1_k127_4933390_32	525367.HMPREF0556_12379	4.363e-23	108.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,26J18@186820|Listeriaceae	91061|Bacilli	P	Glycine betaine ABC transporter permease	proWX	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
DYD1_k127_4933390_10	1449126.JQKL01000003_gene1756	8.321e-89	311.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,268B4@186813|unclassified Clostridiales	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DYD1_k127_4933390_9	264732.Moth_0236	4.416e-89	307.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,42EYC@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DYD1_k127_4933390_28	1122931.AUAE01000028_gene154	3.965e-33	139.0	COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,2FMYB@200643|Bacteroidia,22WSJ@171551|Porphyromonadaceae	976|Bacteroidetes	F	GTP cyclohydrolase 1	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
DYD1_k127_4933390_20	1120999.JONM01000028_gene162	3.786e-54	199.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,2KPET@206351|Neisseriales	206351|Neisseriales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
DYD1_k127_4933390_27	521011.Mpal_2207	2.305e-37	155.0	COG2404@1|root,arCOG00423@2157|Archaea,2XTAE@28890|Euryarchaeota	28890|Euryarchaeota	S	phosphohydrolase (DHH superfamily)	-	-	-	ko:K07097	-	-	-	-	ko00000	-	-	-	-
DYD1_k127_4933390_22	391037.Sare_2200	2.632e-50	191.0	COG2040@1|root,COG2040@2|Bacteria,2GIWK@201174|Actinobacteria,4DIG6@85008|Micromonosporales	201174|Actinobacteria	E	Homocysteine S-methyltransferase	mmuM	-	2.1.1.10	ko:K00547,ko:K21169	ko00270,ko01059,ko01100,ko01110,ko01130,map00270,map01059,map01100,map01110,map01130	M00825	R00650	RC00003,RC00035	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
DYD1_k127_4933390_35	1068980.ARVW01000001_gene1361	5.891e-16	89.0	COG3386@1|root,COG3386@2|Bacteria,2IJZG@201174|Actinobacteria	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
DYD1_k127_4933390_39	1279038.KB907352_gene2224	6.007e-07	57.0	COG2322@1|root,COG2322@2|Bacteria,1N3YI@1224|Proteobacteria,2UJ8D@28211|Alphaproteobacteria,2JX8I@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
DYD1_k127_4933390_36	439481.Aboo_0800	1.058e-15	85.0	arCOG13537@1|root,arCOG13537@2157|Archaea,2Y1U2@28890|Euryarchaeota,3F2T4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4933390_25	386456.JQKN01000016_gene887	5.828e-39	159.0	COG0517@1|root,arCOG00600@2157|Archaea,2Y88W@28890|Euryarchaeota,23NZQ@183925|Methanobacteria	183925|Methanobacteria	S	SMART Cystathionine beta-synthase, core	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DYD1_k127_4933390_21	192952.MM_2532	2.606e-53	204.0	COG3174@1|root,arCOG04203@2157|Archaea,2XT0W@28890|Euryarchaeota,2N9ST@224756|Methanomicrobia	224756|Methanomicrobia	P	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
DYD1_k127_4933390_16	634497.HAH_1426	4.824e-66	243.0	COG0697@1|root,arCOG00271@2157|Archaea,2XT64@28890|Euryarchaeota,23TZT@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_4933390_23	1123371.ATXH01000003_gene1946	9.997e-48	185.0	COG3359@1|root,COG3359@2|Bacteria,2GHTB@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
DYD1_k127_4933390_6	477974.Daud_2078	9.569e-102	341.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
DYD1_k127_4933390_7	1121324.CLIT_13c01530	1.618e-99	335.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25QQ5@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DYD1_k127_4933390_37	1094980.Mpsy_1184	6.625e-09	70.0	arCOG02538@1|root,arCOG02544@1|root,arCOG06534@1|root,arCOG02538@2157|Archaea,arCOG02544@2157|Archaea,arCOG06534@2157|Archaea,2Y6ZG@28890|Euryarchaeota,2NAWQ@224756|Methanomicrobia	2157|Archaea	S	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,NosD,PKD,PQQ_3,Peptidase_S8,S-layer
DYD1_k127_4933390_1	673860.AciM339_0590	1.13e-155	510.0	COG0269@1|root,arCOG00053@2157|Archaea,2XV47@28890|Euryarchaeota,3F2IP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Aldolase/RraA	-	-	4.1.2.43,5.3.1.27	ko:K13831	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R05339,R09780	RC00377,RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,RraA-like
DYD1_k127_4933390_33	985053.VMUT_1670	9.358e-21	99.0	COG2101@1|root,arCOG01764@2157|Archaea,2XQ5U@28889|Crenarchaeota	28889|Crenarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbp	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DYD1_k127_4933390_18	439481.Aboo_0370	1.03e-60	220.0	COG1831@1|root,arCOG00893@2157|Archaea,2XTX7@28890|Euryarchaeota,3F2KE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	TatD related DNase	tatD	-	-	ko:K07049	-	-	-	-	ko00000	-	-	-	TatD_DNase
DYD1_k127_4933390_0	439481.Aboo_1389	8.665e-156	505.0	COG0034@1|root,arCOG00093@2157|Archaea,2XSWJ@28890|Euryarchaeota,3F2FP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
DYD1_k127_4933390_42	1502852.FG94_02397	0.0002413	55.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VIXC@28216|Betaproteobacteria,477GD@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Subtilase family	mprA	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DYD1_k127_4933390_12	696369.KI912183_gene843	1.113e-84	299.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DYD1_k127_4933390_5	1236689.MMALV_02050	4.302e-115	388.0	COG1008@1|root,arCOG01538@2157|Archaea	2157|Archaea	C	COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M)	nuoM	-	1.5.98.3,1.6.5.3	ko:K00342,ko:K22168	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	Oxidored_q5_N,Proton_antipo_M
DYD1_k127_4933390_2	1236689.MMALV_02040	2.064e-149	497.0	COG1009@1|root,arCOG01539@2157|Archaea,2Y85E@28890|Euryarchaeota	28890|Euryarchaeota	C	Proton-conducting membrane transporter	-	-	-	ko:K05565,ko:K12137	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
DYD1_k127_4933390_31	1094980.Mpsy_2574	8.768e-24	104.0	COG0713@1|root,arCOG03073@2157|Archaea,2XXW4@28890|Euryarchaeota,2NB01@224756|Methanomicrobia	224756|Methanomicrobia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	1.5.98.3	ko:K22166	-	-	-	-	ko00000,ko01000	3.D.9.1	-	-	Oxidored_q2
DYD1_k127_4933390_38	886293.Sinac_5552	8.607e-09	63.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
DYD1_k127_4933390_29	273116.14325373	2.527e-27	119.0	COG1143@1|root,arCOG01543@2157|Archaea,2Y79M@28890|Euryarchaeota,241VP@183967|Thermoplasmata	183967|Thermoplasmata	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
DYD1_k127_4933390_14	997346.HMPREF9374_2380	2.258e-76	268.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,4HC8R@91061|Bacilli,27AZZ@186824|Thermoactinomycetaceae	91061|Bacilli	C	NADH dehydrogenase	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
DYD1_k127_4933390_3	649639.Bcell_4062	4.142e-123	406.0	COG0649@1|root,COG0649@2|Bacteria,1TQAR@1239|Firmicutes,4HA4Y@91061|Bacilli,1ZBPG@1386|Bacillus	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
DYD1_k127_4933390_30	222984.JNCS01000001_gene1919	7.518e-27	118.0	COG0649@1|root,arCOG01548@2157|Archaea,2XTWF@28890|Euryarchaeota,23U6Q@183963|Halobacteria	183963|Halobacteria	C	COG0852 NADH ubiquinone oxidoreductase 27 kD subunit	-	-	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
DYD1_k127_4933390_17	986075.CathTA2_2803	1.235e-62	220.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,4HACH@91061|Bacilli	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DYD1_k127_4933390_34	931627.MycrhDRAFT_1357	9.142e-19	90.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,239AP@1762|Mycobacteriaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DYD1_k127_4933390_26	1304284.L21TH_2417	2.121e-38	162.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,36HXX@31979|Clostridiaceae	186801|Clostridia	M	Subtilase family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
DYD1_k127_4933390_24	439481.Aboo_0416	1.618e-39	159.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,3F2MK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	RibD C-terminal domain	ribG	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
DYD1_k127_4933390_41	439481.Aboo_0014	2.176e-05	57.0	arCOG02780@1|root,arCOG02780@2157|Archaea,2Y714@28890|Euryarchaeota,3F34G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4933390_15	342949.PNA2_1747	3.117e-68	252.0	COG2108@1|root,arCOG00932@2157|Archaea,2XU78@28890|Euryarchaeota,243PN@183968|Thermococci	183968|Thermococci	S	4Fe-4S single cluster domain	-	-	-	ko:K07129	-	-	-	-	ko00000	-	-	-	Fer4_14,Radical_SAM
DYD1_k127_4933390_13	448385.sce6815	1.848e-76	269.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2YV6M@29|Myxococcales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DYD1_k127_4933390_4	502025.Hoch_6339	9.231e-120	396.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DYD1_k127_4933390_8	717605.Theco_1426	3.098e-97	336.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,26RXA@186822|Paenibacillaceae	91061|Bacilli	JKL	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity	cshA	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
DYD1_k127_4933390_19	644281.MFS40622_0654	2.899e-54	197.0	COG0066@1|root,arCOG02230@2157|Archaea,2XTXJ@28890|Euryarchaeota,23QQ2@183939|Methanococci	183939|Methanococci	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
DYD1_k127_4933390_11	565033.GACE_1998	1.497e-86	297.0	COG0065@1|root,arCOG01698@2157|Archaea,2XTWH@28890|Euryarchaeota,24616@183980|Archaeoglobi	183980|Archaeoglobi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DYD1_k127_4978414_27	1476583.DEIPH_ctg052orf0066	3.726e-20	101.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DYD1_k127_4978414_11	457429.ABJI02000332_gene2564	4.157e-55	205.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
DYD1_k127_4978414_24	1197130.BAFM01000025_gene3012	4.887e-22	108.0	COG1836@1|root,arCOG02245@2157|Archaea,2XTBR@28890|Euryarchaeota,23S2I@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
DYD1_k127_4978414_23	1220534.B655_2250	2.798e-26	117.0	COG1321@1|root,arCOG02099@2157|Archaea,2XSWC@28890|Euryarchaeota,23P0S@183925|Methanobacteria	183925|Methanobacteria	K	Iron dependent	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
DYD1_k127_4978414_17	1236689.MMALV_15330	3.413e-38	148.0	COG0361@1|root,arCOG01179@2157|Archaea,2XXX0@28890|Euryarchaeota,3F2RM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	eif1a	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
DYD1_k127_4978414_32	387631.Asulf_00018	1.598e-07	59.0	2BVY9@1|root,2N553@2157|Archaea,2Y1ZH@28890|Euryarchaeota,246I9@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4978414_29	1227484.C471_07846	4.718e-09	67.0	COG1617@1|root,arCOG02197@2157|Archaea,2XXRY@28890|Euryarchaeota,23W8H@183963|Halobacteria	183963|Halobacteria	S	KEOPS complex Cgi121-like subunit	cgi121	-	-	ko:K09119	-	-	-	-	ko00000,ko03016	-	-	-	CGI-121
DYD1_k127_4978414_0	351160.RCIX575	2.053e-164	552.0	COG1204@1|root,arCOG00553@2157|Archaea,2XSV4@28890|Euryarchaeota,2N9A8@224756|Methanomicrobia	224756|Methanomicrobia	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
DYD1_k127_4978414_5	456442.Mboo_1967	1.609e-75	265.0	COG0489@1|root,arCOG00585@2157|Archaea,2XTU2@28890|Euryarchaeota,2N9IC@224756|Methanomicrobia	224756|Methanomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
DYD1_k127_4978414_22	688269.Theth_0209	7.611e-28	119.0	COG0394@1|root,COG0394@2|Bacteria,2GDH0@200918|Thermotogae	200918|Thermotogae	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
DYD1_k127_4978414_35	926562.Oweho_0579	6.081e-06	59.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,Laminin_G_3,MAM,PKD
DYD1_k127_4978414_30	935567.JAES01000012_gene900	4.222e-08	60.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1X6DN@135614|Xanthomonadales	135614|Xanthomonadales	C	Part of a membrane complex involved in electron transport	ydgM	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
DYD1_k127_4978414_3	635013.TherJR_1222	3.203e-100	360.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,266U6@186807|Peptococcaceae	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
DYD1_k127_4978414_33	1283287.KB822575_gene454	1.243e-06	58.0	COG0695@1|root,COG0695@2|Bacteria,2IR0P@201174|Actinobacteria,4DS21@85009|Propionibacteriales	201174|Actinobacteria	O	Glutaredoxin-like domain (DUF836)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
DYD1_k127_4978414_18	309800.C498_14528	7.211e-35	143.0	COG1290@1|root,arCOG04594@2157|Archaea,2XUW1@28890|Euryarchaeota,23S8Q@183963|Halobacteria	183963|Halobacteria	C	COG1290 Cytochrome b subunit of the bc complex	petD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
DYD1_k127_4978414_4	1071085.KK033114_gene683	1.099e-79	275.0	COG1290@1|root,arCOG01721@2157|Archaea,2XUQH@28890|Euryarchaeota,23TXF@183963|Halobacteria	183963|Halobacteria	C	COG1290 Cytochrome b subunit of the bc complex	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
DYD1_k127_4978414_20	795797.C497_11548	8.978e-29	126.0	COG0723@1|root,arCOG04595@2157|Archaea,2XU6P@28890|Euryarchaeota,23SAN@183963|Halobacteria	183963|Halobacteria	C	COG0723 Rieske Fe-S protein	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
DYD1_k127_4978414_31	1070774.J07HN4v3_02274	6.1e-08	58.0	arCOG04596@1|root,arCOG04596@2157|Archaea,2XX20@28890|Euryarchaeota,23VPS@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4978414_26	1234595.C725_2021	9.531e-21	104.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2U73K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
DYD1_k127_4978414_14	572546.Arcpr_0294	9.29e-45	168.0	COG0315@1|root,arCOG01530@2157|Archaea,2XWHQ@28890|Euryarchaeota,24741@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
DYD1_k127_4978414_15	1227484.C471_03468	5.293e-41	159.0	COG0521@1|root,arCOG00214@2157|Archaea,2XWJF@28890|Euryarchaeota,23VB0@183963|Halobacteria	183963|Halobacteria	H	COG0521 Molybdopterin biosynthesis enzymes	moaB2	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
DYD1_k127_4978414_8	593117.TGAM_1944	1.048e-66	253.0	COG0303@1|root,arCOG00217@2157|Archaea,2XT2V@28890|Euryarchaeota,242PT@183968|Thermococci	183968|Thermococci	H	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DYD1_k127_4978414_6	1247649.D560_2742	3.03e-72	253.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,3T3A0@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
DYD1_k127_4978414_9	469383.Cwoe_3968	3.536e-64	230.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CPJW@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
DYD1_k127_4978414_13	1408226.T233_00353	2.085e-46	185.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,4B1HP@81852|Enterococcaceae	91061|Bacilli	U	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
DYD1_k127_4978414_7	1118054.CAGW01000061_gene2386	2.857e-67	252.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,26URK@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
DYD1_k127_4978414_21	1410618.JNKI01000029_gene1164	1.238e-28	130.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H37Z@909932|Negativicutes	909932|Negativicutes	E	Ligand-binding protein	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
DYD1_k127_4978414_36	797209.ZOD2009_12280	0.000212	51.0	COG3413@1|root,arCOG02271@2157|Archaea,2XU8X@28890|Euryarchaeota,23THS@183963|Halobacteria	183963|Halobacteria	K	Bacterio-opsin activator HTH domain-containing protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
DYD1_k127_4978414_25	1172188.KB911824_gene3399	1.534e-21	110.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4978414_1	391623.TERMP_00751	1.859e-136	448.0	COG0017@1|root,arCOG00406@2157|Archaea,2XTRE@28890|Euryarchaeota,242Q1@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K22503	ko00970,map00970	M00359	R05577	RC00055,RC00523	ko00000,ko00001,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DYD1_k127_4978414_10	1054217.TALC_00077	1.414e-58	213.0	COG1701@1|root,arCOG04262@2157|Archaea,2XTAP@28890|Euryarchaeota	28890|Euryarchaeota	S	protein conserved in archaea	panC	-	6.3.2.36	ko:K09722	ko00410,ko00770,ko01100,map00410,map00770,map01100	-	R09379	RC00096,RC00141	ko00000,ko00001,ko01000	-	-	-	PPS_PS
DYD1_k127_4978414_19	224324.aq_2197	1.381e-31	140.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
DYD1_k127_4978414_12	1236689.MMALV_13650	3.549e-53	198.0	COG1890@1|root,arCOG04186@2157|Archaea,2XSX9@28890|Euryarchaeota,3F2MY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS1 family	rps3ae	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
DYD1_k127_4978414_28	266117.Rxyl_0026	2.031e-09	67.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
DYD1_k127_4978414_16	391625.PPSIR1_36457	6.511e-41	173.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
DYD1_k127_4978414_34	1123508.JH636441_gene3082	2.431e-06	57.0	COG0745@1|root,COG0745@2|Bacteria,2J1NZ@203682|Planctomycetes	203682|Planctomycetes	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_4978414_2	765420.OSCT_0507	2.532e-126	453.0	COG0236@1|root,COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0236@2|Bacteria,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,2G68I@200795|Chloroflexi,3765Y@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	ko:K15314	ko01059,ko01130,map01059,map01130	M00824,M00825	R11435	-	ko00000,ko00001,ko00002,ko01008	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
DYD1_k127_5004188_0	323261.Noc_0672	1.681e-124	413.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,1RZGN@1236|Gammaproteobacteria,1X1HI@135613|Chromatiales	135613|Chromatiales	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DUF772
DYD1_k127_5004188_1	1267535.KB906767_gene2136	0.0001561	44.0	COG0673@1|root,COG0673@2|Bacteria,3Y78W@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DYD1_k127_5014745_10	523845.AQXV01000050_gene969	7.24e-17	81.0	arCOG05874@1|root,arCOG05874@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5014745_14	234267.Acid_7131	9.692e-12	76.0	COG3324@1|root,COG3324@2|Bacteria,3Y5KZ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
DYD1_k127_5014745_0	272558.10173163	6.798e-89	316.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus	91061|Bacilli	S	ABC transporter	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
DYD1_k127_5014745_2	926554.KI912640_gene1279	1.289e-74	258.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
DYD1_k127_5014745_18	191610.CATYP_03375	0.0001326	51.0	COG2259@1|root,COG2259@2|Bacteria,2GR8Z@201174|Actinobacteria,22NK5@1653|Corynebacteriaceae	201174|Actinobacteria	S	membrane	mhqP	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
DYD1_k127_5014745_1	1236689.MMALV_03010	2.034e-81	280.0	COG0638@1|root,arCOG00971@2157|Archaea,2XUKA@28890|Euryarchaeota,3F2G0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
DYD1_k127_5014745_7	1379698.RBG1_1C00001G0584	2.519e-22	115.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.24.40	ko:K01406,ko:K14274,ko:K20276,ko:K21449	ko00040,ko01503,ko02024,map00040,map01503,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL
DYD1_k127_5014745_3	880074.BARVI_00325	7.902e-70	247.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,2FNX9@200643|Bacteroidia,22WRW@171551|Porphyromonadaceae	976|Bacteroidetes	P	K -dependent Na Ca exchanger	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DYD1_k127_5014745_13	443906.CMM_0825	3.029e-12	80.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DYD1_k127_5014745_11	1094980.Mpsy_2070	4.348e-16	87.0	COG1658@1|root,arCOG01486@2157|Archaea,2Y0G2@28890|Euryarchaeota,2NA2F@224756|Methanomicrobia	224756|Methanomicrobia	L	metal ion binding	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_4
DYD1_k127_5014745_9	593750.Metfor_2125	6.004e-18	87.0	COG1872@1|root,arCOG04058@2157|Archaea,2XZV9@28890|Euryarchaeota,2N9YJ@224756|Methanomicrobia	224756|Methanomicrobia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
DYD1_k127_5014745_17	694430.Natoc_0599	2.202e-07	62.0	COG3413@1|root,arCOG02272@2157|Archaea,2XUQ0@28890|Euryarchaeota,23SMI@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_10
DYD1_k127_5014745_4	410358.Mlab_1483	1.822e-49	184.0	COG2238@1|root,arCOG01344@2157|Archaea,2XXA6@28890|Euryarchaeota,2N9QY@224756|Methanomicrobia	224756|Methanomicrobia	J	May be involved in maturation of the 30S ribosomal subunit	rps19e	-	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
DYD1_k127_5014745_12	589924.Ferp_0032	1.197e-14	79.0	COG2118@1|root,arCOG04179@2157|Archaea,2XZUR@28890|Euryarchaeota,246BU@183980|Archaeoglobi	183980|Archaeoglobi	L	Belongs to the PDCD5 family	-	-	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
DYD1_k127_5014745_16	439481.Aboo_0026	1.372e-09	65.0	COG2167@1|root,arCOG04177@2157|Archaea,2Y6Y7@28890|Euryarchaeota,3F2VP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	-	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
DYD1_k127_5014745_8	694440.JOMF01000008_gene942	8.637e-21	99.0	COG2097@1|root,arCOG04473@2157|Archaea,2XYWX@28890|Euryarchaeota,2N9YU@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the eukaryotic ribosomal protein eL31 family	rpl31e	-	-	ko:K02910	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31e
DYD1_k127_5014745_5	1261545.MBE-HAL_0915	1.088e-44	173.0	COG1976@1|root,arCOG04176@2157|Archaea,2XU7N@28890|Euryarchaeota,23SZE@183963|Halobacteria	183963|Halobacteria	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	-	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
DYD1_k127_5014745_19	192952.MM_0808	0.0007497	46.0	COG2157@1|root,arCOG04175@2157|Archaea,2Y6W8@28890|Euryarchaeota,2NA5B@224756|Methanomicrobia	224756|Methanomicrobia	J	Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A	rplX	-	-	ko:K02944	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18A
DYD1_k127_5014745_6	314271.RB2654_18011	2.558e-24	111.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Type I secretion membrane fusion protein, HlyD	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
DYD1_k127_5057299_10	931277.C448_08614	3.778e-06	58.0	COG3364@1|root,arCOG04417@2157|Archaea,2XU3V@28890|Euryarchaeota,23VTC@183963|Halobacteria	183963|Halobacteria	CP	COG3364 Zn-ribbon containing protein	oapC	-	-	ko:K07163	-	-	-	-	ko00000	-	-	-	DUF2072
DYD1_k127_5057299_6	693661.Arcve_0234	9.743e-26	111.0	COG3365@1|root,arCOG04416@2157|Archaea,2XX2F@28890|Euryarchaeota,246AQ@183980|Archaeoglobi	183980|Archaeoglobi	S	Uncharacterized protein conserved in archaea (DUF2073)	-	-	-	ko:K09743	-	-	-	-	ko00000	-	-	-	DUF2073
DYD1_k127_5057299_3	224325.AF_1181	1.553e-86	290.0	COG1100@1|root,arCOG00354@2157|Archaea,2XT36@28890|Euryarchaeota,246VT@183980|Archaeoglobi	183980|Archaeoglobi	S	GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	MMR_HSR1
DYD1_k127_5057299_11	1122130.AUHN01000009_gene755	5.109e-06	55.0	2DUW4@1|root,32UXY@2|Bacteria,2IJWI@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
DYD1_k127_5057299_7	1894.JOER01000017_gene4885	1.824e-21	109.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	DUF4082,RicinB_lectin_2
DYD1_k127_5057299_2	555079.Toce_1529	1.572e-87	312.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,2494Y@186801|Clostridia,42FDX@68295|Thermoanaerobacterales	186801|Clostridia	S	pfam abc1	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
DYD1_k127_5057299_8	1449355.JQNR01000005_gene2326	7.001e-08	59.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
DYD1_k127_5057299_9	315730.BcerKBAB4_2191	9.377e-08	59.0	COG3324@1|root,COG3324@2|Bacteria,1V48C@1239|Firmicutes,4HHTZ@91061|Bacilli,1ZFPT@1386|Bacillus	91061|Bacilli	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
DYD1_k127_5057299_4	331678.Cphamn1_1547	1.538e-46	178.0	COG0784@1|root,COG0784@2|Bacteria,1FEV7@1090|Chlorobi	1090|Chlorobi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DYD1_k127_5057299_0	694429.Pyrfu_0404	2.226e-104	350.0	COG0162@1|root,arCOG01886@2157|Archaea,2XPU5@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
DYD1_k127_5057299_1	673860.AciM339_1307	1.426e-93	325.0	COG0552@1|root,arCOG01227@2157|Archaea,2XUBI@28890|Euryarchaeota,3F2GR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DYD1_k127_5067509_2	351160.LRC17	2.84e-147	477.0	COG0206@1|root,arCOG02201@2157|Archaea,2XSV8@28890|Euryarchaeota,2N934@224756|Methanomicrobia	224756|Methanomicrobia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ-1	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DYD1_k127_5067509_5	439481.Aboo_0862	4.113e-74	255.0	COG0081@1|root,arCOG04289@2157|Archaea,2XTJF@28890|Euryarchaeota,3F2IX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DYD1_k127_5067509_4	565033.GACE_1395	9.748e-76	266.0	COG0244@1|root,arCOG04288@2157|Archaea,2XU7C@28890|Euryarchaeota,245X9@183980|Archaeoglobi	183980|Archaeoglobi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DYD1_k127_5067509_13	69014.TK1415	8.447e-25	106.0	COG2058@1|root,arCOG04287@2157|Archaea,2XYQ9@28890|Euryarchaeota,244BE@183968|Thermococci	183968|Thermococci	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	-	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
DYD1_k127_5067509_8	290397.Adeh_1677	3.016e-46	183.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2YX9Q@29|Myxococcales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
DYD1_k127_5067509_0	439481.Aboo_1408	5.305e-239	760.0	COG0466@1|root,arCOG02160@2157|Archaea,2XTT0@28890|Euryarchaeota,3F2HW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Belongs to the peptidase S16 family	lon	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
DYD1_k127_5067509_17	591019.Shell_0909	8.873e-15	79.0	COG1848@1|root,arCOG00713@2157|Archaea,2XRD1@28889|Crenarchaeota	28889|Crenarchaeota	V	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
DYD1_k127_5067509_6	673860.AciM339_0842	7.396e-69	244.0	COG0462@1|root,arCOG00067@2157|Archaea,2XTA8@28890|Euryarchaeota,3F2FN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
DYD1_k127_5067509_21	273068.TTE1177	3.25e-06	59.0	COG0842@1|root,COG0842@2|Bacteria,1VAB2@1239|Firmicutes	1239|Firmicutes	V	Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DYD1_k127_5067509_7	1198449.ACAM_1584	1.21e-58	217.0	COG1131@1|root,arCOG00194@2157|Archaea,2XPS7@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_5067509_23	1278308.KB907076_gene1544	1.124e-05	55.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4FPP9@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
DYD1_k127_5067509_9	1365176.N186_09460	9.438e-42	167.0	COG0535@1|root,arCOG00940@2157|Archaea,2XPP5@28889|Crenarchaeota	28889|Crenarchaeota	S	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	SPASM
DYD1_k127_5067509_14	1340434.AXVA01000045_gene3326	9.725e-20	94.0	COG2315@1|root,COG2315@2|Bacteria,1TZ0D@1239|Firmicutes,4I86V@91061|Bacilli,1ZG95@1386|Bacillus	91061|Bacilli	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
DYD1_k127_5067509_19	273075.Ta1426m	1.217e-07	57.0	COG2443@1|root,arCOG02204@2157|Archaea,2Y6IT@28890|Euryarchaeota,241W4@183967|Thermoplasmata	183967|Thermoplasmata	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	-	-	-	ko:K07342	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.7,3.A.5.8,3.A.5.9	-	-	-
DYD1_k127_5067509_15	1459636.NTE_02005	1.844e-19	101.0	COG1522@1|root,arCOG01586@2157|Archaea	2157|Archaea	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_AsnC-type
DYD1_k127_5067509_18	981384.AEYW01000016_gene26	4.767e-09	65.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	mxaD	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Polyketide_cyc2
DYD1_k127_5067509_1	69014.TK1170	1.17e-211	676.0	COG0441@1|root,arCOG00401@2157|Archaea,2XTFI@28890|Euryarchaeota,242P8@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
DYD1_k127_5067509_10	2340.JV46_14180	3.814e-40	169.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	-	-	3.1.4.52	ko:K21024	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9,SBP_bac_3
DYD1_k127_5067509_20	1189619.pgond44_07000	3.37e-07	63.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,4PKJ2@976|Bacteroidetes,1IJAK@117743|Flavobacteriia,4C3DY@83612|Psychroflexus	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,SpoIIE
DYD1_k127_5067509_3	439481.Aboo_0452	5.918e-83	290.0	COG0006@1|root,arCOG01000@2157|Archaea,2XTI9@28890|Euryarchaeota,3F2JJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Belongs to the peptidase M24B family	pepQ1	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
DYD1_k127_5067509_16	1122963.AUHB01000018_gene2095	1.44e-17	90.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,36YQP@31993|Methylocystaceae	28211|Alphaproteobacteria	D	CrcB-like protein, Camphor Resistance (CrcB)	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
DYD1_k127_5067509_11	1333523.L593_02885	3.217e-29	133.0	COG1784@1|root,arCOG04469@2157|Archaea,2XSZ3@28890|Euryarchaeota,23SUU@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	ko:K08971	-	-	-	-	ko00000	-	-	-	TctA
DYD1_k127_5067509_22	351160.LRC36	5.036e-06	56.0	COG3612@1|root,arCOG04418@2157|Archaea,2XXT8@28890|Euryarchaeota,2NA4A@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterized protein conserved in archaea (DUF2240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2240
DYD1_k127_5067509_26	391165.GbCGDNIH1_0769	0.0008344	51.0	COG1411@1|root,COG1411@2|Bacteria,1RHWE@1224|Proteobacteria,2U80I@28211|Alphaproteobacteria,2JTSE@204441|Rhodospirillales	204441|Rhodospirillales	S	Histidine biosynthesis protein	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DYD1_k127_5067509_12	479435.Kfla_5058	5.906e-25	117.0	COG3345@1|root,COG3345@2|Bacteria,2I6NS@201174|Actinobacteria	201174|Actinobacteria	G	Ricin-type beta-trefoil lectin domain-like	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
DYD1_k127_5067509_24	1205910.B005_0500	0.0001099	55.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4EI3T@85012|Streptosporangiales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_5067509_25	1123013.AUIC01000003_gene299	0.0001254	50.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4FKQD@85023|Microbacteriaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DYD1_k127_5084006_4	3067.XP_002953816.1	2.491e-10	71.0	COG0633@1|root,2RXME@2759|Eukaryota,37TSK@33090|Viridiplantae,34NXT@3041|Chlorophyta	3041|Chlorophyta	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
DYD1_k127_5084006_2	1430440.MGMSRv2_3573	1.485e-50	190.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2U10V@28211|Alphaproteobacteria,2JRBZ@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
DYD1_k127_5084006_3	81824.XP_001744135.1	9.354e-35	144.0	COG1413@1|root,KOG0567@2759|Eukaryota,38FQT@33154|Opisthokonta	33154|Opisthokonta	C	Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)- L-lysine intermediate to form hypusine, an essential post- translational modification only found in mature eIF-5A factor	LIA1	GO:0000226,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005789,GO:0005829,GO:0006417,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0008150,GO:0008152,GO:0008283,GO:0008612,GO:0009058,GO:0009268,GO:0009628,GO:0009889,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010467,GO:0010468,GO:0010506,GO:0010508,GO:0010556,GO:0010608,GO:0012505,GO:0016020,GO:0016043,GO:0016491,GO:0016705,GO:0018193,GO:0018205,GO:0019135,GO:0019222,GO:0019538,GO:0030447,GO:0031323,GO:0031325,GO:0031326,GO:0031329,GO:0031331,GO:0031984,GO:0032268,GO:0034248,GO:0036176,GO:0036177,GO:0036178,GO:0036211,GO:0040007,GO:0042175,GO:0042710,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044010,GO:0044011,GO:0044182,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044764,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051604,GO:0051703,GO:0051704,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090605,GO:0090609,GO:0098827,GO:1901564,GO:2000112,GO:2000765	1.14.99.29	ko:K06072,ko:K08187	ko04919,ko04974,map04919,map04974	-	-	-	ko00000,ko00001,ko01000,ko02000	2.A.1.13	-	-	HEAT_2,HEAT_PBS
DYD1_k127_5084006_1	1121011.AUCB01000007_gene1316	4.897e-73	254.0	COG2159@1|root,COG2159@2|Bacteria,4NJP9@976|Bacteroidetes,1HXKV@117743|Flavobacteriia,23FXD@178469|Arenibacter	976|Bacteroidetes	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DYD1_k127_5084006_5	1459636.NTE_03536	3.924e-05	55.0	COG1522@1|root,arCOG01586@2157|Archaea,41T3N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_5084006_0	1236689.MMALV_00330	9.384e-168	531.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,3F2FH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DYD1_k127_5155039_0	99598.Cal7507_4154	1.063e-73	260.0	COG3547@1|root,COG3547@2|Bacteria,1G5MH@1117|Cyanobacteria,1HU7K@1161|Nostocales	1117|Cyanobacteria	L	COGs COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
DYD1_k127_5155039_1	694429.Pyrfu_1298	4.456e-46	171.0	COG0182@1|root,arCOG01123@2157|Archaea,2XPZU@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
DYD1_k127_523399_19	596152.DesU5LDRAFT_2681	1.979e-27	114.0	2DN97@1|root,32W7A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_523399_31	304371.MCP_2072	4.531e-14	82.0	COG1082@1|root,arCOG01895@2157|Archaea	2157|Archaea	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,NeuB,SAF
DYD1_k127_523399_1	1183438.GKIL_2511	4.991e-156	510.0	COG2986@1|root,COG2986@2|Bacteria,1G3FJ@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	4.3.1.24,4.3.1.3	ko:K01745,ko:K10775	ko00340,ko00360,ko00940,ko01100,ko01110,map00340,map00360,map00940,map01100,map01110	M00039,M00045,M00137,M00350	R00697,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DYD1_k127_523399_26	399549.Msed_1970	2.234e-18	89.0	COG0640@1|root,arCOG00731@2157|Archaea,2XR3K@28889|Crenarchaeota	28889|Crenarchaeota	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
DYD1_k127_523399_0	1341151.ASZU01000012_gene1687	2.587e-220	696.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,27BE2@186824|Thermoactinomycetaceae	91061|Bacilli	E	Urocanase C-terminal domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
DYD1_k127_523399_5	673860.AciM339_1144	8.967e-95	325.0	COG0045@1|root,arCOG01337@2157|Archaea,2XTSC@28890|Euryarchaeota,3F389@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	ATP-grasp domain	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DYD1_k127_523399_4	1056495.Calag_0481	1.031e-100	335.0	COG0074@1|root,arCOG01339@2157|Archaea,2XPW3@28889|Crenarchaeota	28889|Crenarchaeota	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA,Succ_CoA_lig
DYD1_k127_523399_29	28444.JODQ01000010_gene3190	5.826e-16	91.0	COG5276@1|root,COG5276@2|Bacteria,2IDWW@201174|Actinobacteria,4EH21@85012|Streptosporangiales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_523399_21	324602.Caur_1591	2.253e-26	123.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ydeG	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
DYD1_k127_523399_30	580332.Slit_1984	7.679e-15	76.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
DYD1_k127_523399_36	1267535.KB906767_gene1343	1.107e-10	67.0	COG2085@1|root,COG2085@2|Bacteria,3Y5CN@57723|Acidobacteria,2JNMR@204432|Acidobacteriia	204432|Acidobacteriia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
DYD1_k127_523399_23	1123253.AUBD01000002_gene1329	3.794e-26	116.0	COG0454@1|root,COG0456@2|Bacteria,1RJ1K@1224|Proteobacteria,1S6RV@1236|Gammaproteobacteria,1X6U1@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD1_k127_523399_14	246969.TAM4_91	1.072e-35	140.0	COG1358@1|root,arCOG01751@2157|Archaea,2XX4C@28890|Euryarchaeota,2444W@183968|Thermococci	183968|Thermococci	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
DYD1_k127_523399_16	1236689.MMALV_01050	8.623e-31	121.0	COG2053@1|root,arCOG04314@2157|Archaea,2XYMV@28890|Euryarchaeota,3F2S8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
DYD1_k127_523399_27	224325.AF_0766	7.66e-18	84.0	COG2075@1|root,arCOG01950@2157|Archaea,2Y00Q@28890|Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl24e	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
DYD1_k127_523399_12	521098.Aaci_1691	1.364e-47	180.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,279QU@186823|Alicyclobacillaceae	91061|Bacilli	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DYD1_k127_523399_33	1121013.P873_07510	5.538e-13	75.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales	135614|Xanthomonadales	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
DYD1_k127_523399_9	1449126.JQKL01000009_gene370	7.073e-63	227.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	rimK	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Dala_Dala_lig_C,RLAN,RimK
DYD1_k127_523399_38	304371.MCP_0018	3.676e-08	63.0	arCOG03443@1|root,arCOG03443@2157|Archaea,2Y0YU@28890|Euryarchaeota	28890|Euryarchaeota	S	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RLAN
DYD1_k127_523399_18	673860.AciM339_0649	1.837e-27	118.0	arCOG03678@1|root,arCOG03678@2157|Archaea,2XZ63@28890|Euryarchaeota,3F2RS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_523399_41	882378.RBRH_01830	1.476e-05	52.0	COG5378@1|root,COG5378@2|Bacteria,1PIIF@1224|Proteobacteria,2W75C@28216|Betaproteobacteria,1KDV4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_2
DYD1_k127_523399_34	756883.Halar_2531	2.675e-12	70.0	arCOG07235@1|root,arCOG07235@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_523399_6	880072.Desac_2171	3.474e-77	288.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
DYD1_k127_523399_25	1125863.JAFN01000001_gene546	6.886e-22	101.0	COG2402@1|root,COG2402@2|Bacteria,1NK19@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
DYD1_k127_523399_42	1185652.USDA257_c60430	2.414e-05	55.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U8S1@28211|Alphaproteobacteria,4B9XS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
DYD1_k127_523399_17	441620.Mpop_4832	1.829e-30	132.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,1JR90@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the SOS response-associated peptidase family	MA20_42060	-	-	-	-	-	-	-	-	-	-	-	SRAP
DYD1_k127_523399_37	751944.HALDL1_07605	5.382e-10	69.0	COG2135@1|root,arCOG02784@2157|Archaea,2XSU1@28890|Euryarchaeota,23T51@183963|Halobacteria	183963|Halobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
DYD1_k127_523399_2	290397.Adeh_3929	2.797e-115	381.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
DYD1_k127_523399_32	485913.Krac_8089	1.466e-13	81.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,PD40,Pentapeptide,Pkinase,TIR_2,WD40
DYD1_k127_523399_3	1173024.KI912151_gene1879	4.181e-112	371.0	COG1028@1|root,COG1028@2|Bacteria,1G02R@1117|Cyanobacteria,1JK3B@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DYD1_k127_523399_35	1455608.JDTH01000001_gene2878	4.201e-12	78.0	COG2135@1|root,arCOG02784@2157|Archaea,2XSU1@28890|Euryarchaeota,23T51@183963|Halobacteria	183963|Halobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
DYD1_k127_523399_7	1313301.AUGC01000008_gene492	4.014e-72	261.0	COG0787@1|root,COG0787@2|Bacteria,4NG3U@976|Bacteroidetes	976|Bacteroidetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
DYD1_k127_523399_10	1305737.JAFX01000001_gene2566	1.504e-59	220.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47KFA@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
DYD1_k127_523399_13	1236689.MMALV_07810	1.976e-44	179.0	COG1340@1|root,arCOG01159@2157|Archaea,2XU21@28890|Euryarchaeota,3F2P7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_523399_11	439481.Aboo_1186	1.352e-54	208.0	COG2237@1|root,arCOG04151@2157|Archaea,2XTV5@28890|Euryarchaeota,3F2NQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
DYD1_k127_523399_20	368407.Memar_0398	9.169e-27	119.0	COG1634@1|root,arCOG04303@2157|Archaea,2XT8R@28890|Euryarchaeota,2N9JZ@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP)	mptE	-	2.7.6.3	ko:K07142	ko00790,map00790	-	R03503	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	MAF_flag10
DYD1_k127_523399_24	667014.Thein_2232	4.407e-22	101.0	COG1324@1|root,COG1324@2|Bacteria,2GHXW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
DYD1_k127_523399_8	673860.AciM339_0749	8.155e-69	252.0	COG0517@1|root,COG0750@1|root,arCOG00607@2157|Archaea,arCOG04064@2157|Archaea,2XSZP@28890|Euryarchaeota,3F2KK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
DYD1_k127_523399_28	1411123.JQNH01000001_gene104	4.007e-17	83.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
DYD1_k127_5272108_0	909663.KI867149_gene3375	8.873e-204	644.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MQB6@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DYD1_k127_5272108_18	1131266.ARWQ01000006_gene271	8.178e-29	119.0	arCOG03272@1|root,arCOG03272@2157|Archaea,41T3V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5272108_24	1041930.Mtc_2458	2.6e-16	92.0	COG1719@1|root,arCOG01688@2157|Archaea,2XY7Q@28890|Euryarchaeota,2N9Q7@224756|Methanomicrobia	224756|Methanomicrobia	K	V4R	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	HTH_5,V4R
DYD1_k127_5272108_27	195522.BD01_1199	2.929e-09	63.0	COG2361@1|root,arCOG05024@2157|Archaea,2Y0RU@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
DYD1_k127_5272108_34	670487.Ocepr_2045	4.126e-06	54.0	COG1669@1|root,COG1669@2|Bacteria,1WKNV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
DYD1_k127_5272108_20	1236976.JCM16418_2702	3.252e-24	105.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HKN2@91061|Bacilli,26Y3H@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the HesB IscA family	yutM	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
DYD1_k127_5272108_10	1238450.VIBNISOn1_800062	8.983e-83	286.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,1RQ60@1236|Gammaproteobacteria,1XSWK@135623|Vibrionales	135623|Vibrionales	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
DYD1_k127_5272108_16	935866.JAER01000032_gene2377	2.952e-32	136.0	COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
DYD1_k127_5272108_7	485913.Krac_7275	3.012e-110	377.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
DYD1_k127_5272108_32	1120948.KB903217_gene1367	1.304e-06	60.0	2C75R@1|root,2ZCK5@2|Bacteria,2IBVD@201174|Actinobacteria,4E8JR@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5272108_37	1197477.IA57_05825	0.0004374	52.0	2DZVD@1|root,32VJZ@2|Bacteria,4NUB2@976|Bacteroidetes,1I482@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
DYD1_k127_5272108_5	237368.SCABRO_01193	1.523e-126	425.0	COG0674@1|root,COG0674@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
DYD1_k127_5272108_8	324602.Caur_0953	1.089e-87	299.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia	32061|Chloroflexia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
DYD1_k127_5272108_1	580332.Slit_2174	6.379e-169	553.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VKNA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	aidB_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
DYD1_k127_5272108_19	317655.Sala_2375	1.148e-25	113.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,2U9EX@28211|Alphaproteobacteria,2K64Z@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
DYD1_k127_5272108_39	1408433.JHXV01000023_gene3310	0.0007059	49.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,4NHWS@976|Bacteroidetes,1I0RR@117743|Flavobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18,HTH_AraC
DYD1_k127_5272108_25	1283299.AUKG01000001_gene3042	8.522e-15	78.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
DYD1_k127_5272108_28	749927.AMED_4250	2.999e-09	68.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4E2Z7@85010|Pseudonocardiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
DYD1_k127_5272108_38	1268303.RHODMAR_1397	0.0005956	51.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD1_k127_5272108_36	215803.DB30_2423	0.0001932	53.0	COG1404@1|root,COG3291@1|root,COG3509@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YZ9E@29|Myxococcales	28221|Deltaproteobacteria	OQ	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
DYD1_k127_5272108_35	1219084.AP014508_gene1762	1.974e-05	56.0	COG2251@1|root,COG2251@2|Bacteria,2GCW6@200918|Thermotogae	200918|Thermotogae	S	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5,RNase_H_2
DYD1_k127_5272108_9	368407.Memar_0380	6.092e-85	297.0	COG0389@1|root,arCOG04582@2157|Archaea,2XTZZ@28890|Euryarchaeota,2NAE4@224756|Methanomicrobia	224756|Methanomicrobia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis	dbh	-	2.7.7.7	ko:K04479	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
DYD1_k127_5272108_17	742765.HMPREF9457_02151	3.612e-32	131.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia	186801|Clostridia	O	Antioxidant, AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DYD1_k127_5272108_11	1227488.C477_18245	5.576e-78	281.0	COG1574@1|root,arCOG00691@2157|Archaea,2XUUZ@28890|Euryarchaeota,23SFX@183963|Halobacteria	183963|Halobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DYD1_k127_5272108_3	1121930.AQXG01000016_gene1818	5.547e-144	474.0	COG1757@1|root,COG1757@2|Bacteria,4NFF8@976|Bacteroidetes	976|Bacteroidetes	C	Na H anti-porter	mleN	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
DYD1_k127_5272108_33	751944.HALDL1_12310	2.336e-06	59.0	COG3413@1|root,arCOG02280@2157|Archaea,2XVJ8@28890|Euryarchaeota,23U9I@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
DYD1_k127_5272108_4	1236689.MMALV_16940	3.519e-137	447.0	COG0183@1|root,arCOG01282@2157|Archaea,2XT8C@28890|Euryarchaeota	28890|Euryarchaeota	I	Acetyl-CoA acetyltransferase	yqeF	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD1_k127_5272108_29	1151126.AQYI01000004_gene1049	5.823e-08	60.0	2EGCD@1|root,33A46@2|Bacteria,2HKUV@201174|Actinobacteria,4FQBT@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
DYD1_k127_5272108_23	1347087.CBYO010000016_gene2570	1.626e-17	94.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes,4HCR1@91061|Bacilli	91061|Bacilli	S	Peptidase family M28	ywaD	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28
DYD1_k127_5272108_14	502025.Hoch_0388	1.183e-40	161.0	COG0500@1|root,COG2226@2|Bacteria,1QX9U@1224|Proteobacteria,43C31@68525|delta/epsilon subdivisions,2X7DP@28221|Deltaproteobacteria,2YW1I@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
DYD1_k127_5272108_22	448385.sce2888	6.657e-21	99.0	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,42VMT@68525|delta/epsilon subdivisions,2WPFB@28221|Deltaproteobacteria,2YVIK@29|Myxococcales	28221|Deltaproteobacteria	S	FxsA cytoplasmic membrane protein	fsxA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
DYD1_k127_5272108_6	869210.Marky_0879	4.649e-117	383.0	COG1250@1|root,COG1250@2|Bacteria,1WIN8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DYD1_k127_5272108_2	204669.Acid345_2384	8.514e-149	497.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
DYD1_k127_5272108_31	1385520.N802_11440	9.916e-07	59.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4FF6K@85021|Intrasporangiaceae	201174|Actinobacteria	P	P-type ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
DYD1_k127_5272108_21	68170.KL590484_gene7622	7.388e-24	113.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4E4UE@85010|Pseudonocardiales	201174|Actinobacteria	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1,2.8.4.2	ko:K03325,ko:K03741,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000	2.A.59	-	-	LMWPc
DYD1_k127_5272108_12	1121015.N789_01005	3.436e-75	260.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1S2WT@1236|Gammaproteobacteria,1X562@135614|Xanthomonadales	135614|Xanthomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
DYD1_k127_5272108_30	1280380.KR100_07855	7.147e-07	61.0	COG1345@1|root,COG4886@1|root,COG5276@1|root,COG1345@2|Bacteria,COG4886@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K02396,ko:K13735,ko:K21449	ko02040,ko05100,map02040,map05100	-	-	-	ko00000,ko00001,ko02000,ko02035	1.B.40.2	-	-	BACON,CHU_C,LRR_5
DYD1_k127_5272108_13	287.DR97_5766	1.806e-43	166.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,1SFQ0@1236|Gammaproteobacteria,1YG15@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
DYD1_k127_5272108_15	666685.R2APBS1_1169	1.389e-37	153.0	COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria,1S5CQ@1236|Gammaproteobacteria,1X6F2@135614|Xanthomonadales	135614|Xanthomonadales	J	translation initiation inhibitor, yjgF family	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
DYD1_k127_5349402_19	314271.RB2654_10713	4.118e-53	208.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
DYD1_k127_5349402_36	1235457.C404_00945	1.465e-20	96.0	COG2146@1|root,COG2146@2|Bacteria,1N82Y@1224|Proteobacteria,2VX8W@28216|Betaproteobacteria,1K9E9@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
DYD1_k127_5349402_10	1236689.MMALV_01670	6.153e-90	327.0	COG1199@1|root,arCOG00770@2157|Archaea,2XTH2@28890|Euryarchaeota,3F2IN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	HELICc2	rad3b	-	3.6.4.12	ko:K03722,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD_2,HBB,Helicase_C_2,ResIII
DYD1_k127_5349402_40	1236689.MMALV_02200	4.307e-15	77.0	COG1958@1|root,arCOG00998@2157|Archaea,2Y0B2@28890|Euryarchaeota,3F2ST@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
DYD1_k127_5349402_35	593750.Metfor_1017	2.347e-21	100.0	COG1585@1|root,arCOG01912@2157|Archaea,2Y07X@28890|Euryarchaeota	28890|Euryarchaeota	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
DYD1_k127_5349402_3	1041930.Mtc_1205	8.249e-138	448.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTA2@28890|Euryarchaeota,2N9RK@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DYD1_k127_5349402_52	439481.Aboo_0504	0.00073	44.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTA2@28890|Euryarchaeota,3F2HR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DYD1_k127_5349402_38	1160137.KB907308_gene7545	1.185e-18	97.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria,4FW0U@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	ytpA	GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
DYD1_k127_5349402_32	477641.MODMU_0673	1.205e-29	127.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4ERXM@85013|Frankiales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HAD
DYD1_k127_5349402_14	204669.Acid345_0159	2.628e-63	228.0	COG1606@1|root,COG1606@2|Bacteria,3Y30C@57723|Acidobacteria,2JKD3@204432|Acidobacteriia	204432|Acidobacteriia	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
DYD1_k127_5349402_28	523841.HFX_1672	1.247e-44	178.0	arCOG09395@1|root,arCOG09395@2157|Archaea,2XTUR@28890|Euryarchaeota,23S6T@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
DYD1_k127_5349402_20	309807.SRU_2769	2.884e-51	188.0	COG2128@1|root,COG2128@2|Bacteria,4NN22@976|Bacteroidetes,1FK4T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PA26 p53-induced protein (sestrin)	-	-	-	-	-	-	-	-	-	-	-	-	CMD
DYD1_k127_5349402_44	469382.Hbor_23740	7.831e-11	69.0	COG3794@1|root,arCOG02920@2157|Archaea,2Y7VI@28890|Euryarchaeota,23VT8@183963|Halobacteria	183963|Halobacteria	C	COG3794 Plastocyanin	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD1_k127_5349402_16	1227454.C446_12594	8.499e-62	225.0	arCOG07538@1|root,arCOG07538@2157|Archaea,2XUW4@28890|Euryarchaeota,23TC3@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5349402_29	1459636.NTE_02673	4.384e-44	169.0	arCOG01449@1|root,arCOG01449@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5349402_17	673860.AciM339_1276	2.66e-60	223.0	COG1577@1|root,arCOG01028@2157|Archaea,2XSUB@28890|Euryarchaeota,3F2JQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids	mvk	GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
DYD1_k127_5349402_30	634498.mru_0921	8.481e-40	159.0	COG1608@1|root,arCOG00860@2157|Archaea,2XSUI@28890|Euryarchaeota,23NXS@183925|Methanobacteria	183925|Methanobacteria	I	Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DYD1_k127_5349402_12	348780.NP_0360A	3.278e-75	268.0	COG1304@1|root,arCOG00613@2157|Archaea,2XT6H@28890|Euryarchaeota,23RYT@183963|Halobacteria	183963|Halobacteria	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
DYD1_k127_5349402_13	1220534.B655_0860	1.696e-67	241.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,23NK4@183925|Methanobacteria	183925|Methanobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DYD1_k127_5349402_2	192952.MM_1749	1.284e-160	525.0	COG0008@1|root,arCOG04302@2157|Archaea,2XSYV@28890|Euryarchaeota,2N9CR@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
DYD1_k127_5349402_22	368407.Memar_1425	2.482e-50	193.0	COG0704@1|root,arCOG00318@2157|Archaea,2XUA4@28890|Euryarchaeota,2N9P3@224756|Methanomicrobia	224756|Methanomicrobia	K	Phosphate uptake regulator, PhoU	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
DYD1_k127_5349402_4	768066.HELO_1616	2.246e-116	388.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1XIG9@135619|Oceanospirillales	135619|Oceanospirillales	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DYD1_k127_5349402_31	1118153.MOY_03748	2.961e-30	129.0	COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1XJD4@135619|Oceanospirillales	135619|Oceanospirillales	P	COG1392 Phosphate transport regulator (distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DYD1_k127_5349402_26	1041930.Mtc_2313	2.652e-45	176.0	COG1624@1|root,arCOG04453@2157|Archaea,2XTR1@28890|Euryarchaeota,2N9M8@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a	dacZ	-	-	-	-	-	-	-	-	-	-	-	DisA_N
DYD1_k127_5349402_1	1041930.Mtc_1540	7.436e-171	560.0	COG1855@1|root,arCOG04116@2157|Archaea,2XSZY@28890|Euryarchaeota,2N924@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM PilT protein domain protein	-	-	-	ko:K06865	-	-	-	-	ko00000	-	-	-	KH_1,PIN,T2SSE
DYD1_k127_5349402_33	68199.JNZO01000001_gene815	2.003e-24	118.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,2GNGF@201174|Actinobacteria	201174|Actinobacteria	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF1080
DYD1_k127_5349402_41	1121382.JQKG01000018_gene1082	2.181e-14	77.0	2EC2Y@1|root,3361X@2|Bacteria,1WKKQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Lysine biosynthesis protein LysW	lysW	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	TF_Zn_Ribbon
DYD1_k127_5349402_11	324602.Caur_0334	1.588e-88	301.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi,374VK@32061|Chloroflexia	32061|Chloroflexia	HJ	PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
DYD1_k127_5349402_8	985053.VMUT_1533	8.185e-92	315.0	COG0002@1|root,arCOG00495@2157|Archaea,2XQ3U@28889|Crenarchaeota	28889|Crenarchaeota	E	Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DYD1_k127_5349402_21	1121945.ATXS01000008_gene1923	5.748e-51	194.0	COG0548@1|root,arCOG00862@2157|Archaea,2XTW9@28890|Euryarchaeota,23SW3@183963|Halobacteria	183963|Halobacteria	E	Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis)	lysZ	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DYD1_k127_5349402_5	1489678.RDMS_05740	3.059e-114	380.0	COG4992@1|root,COG4992@2|Bacteria,1WI5J@1297|Deinococcus-Thermus	2|Bacteria	E	Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine	lysJ	-	2.6.1.11,2.6.1.17	ko:K00821,ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Peptidase_M20
DYD1_k127_5349402_18	1382356.JQMP01000004_gene347	1.166e-58	218.0	COG0624@1|root,COG0624@2|Bacteria,2G61X@200795|Chloroflexi,27XIT@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
DYD1_k127_5349402_27	644282.Deba_1551	3.42e-45	172.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42QU8@68525|delta/epsilon subdivisions,2X5Q5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
DYD1_k127_5349402_9	439481.Aboo_0417	1.726e-90	306.0	COG0020@1|root,arCOG01532@2157|Archaea,2XSW1@28890|Euryarchaeota,3F2F2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.89	ko:K15888	ko00900,map00900	-	R09730	RC00279,RC02839	ko00000,ko00001,ko01000	-	-	-	Prenyltransf
DYD1_k127_5349402_24	247490.KSU1_D0672	7.245e-48	179.0	COG0491@1|root,COG0491@2|Bacteria,2IZHE@203682|Planctomycetes	203682|Planctomycetes	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
DYD1_k127_5349402_50	946483.Cenrod_1254	3.938e-06	55.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,4ADZS@80864|Comamonadaceae	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
DYD1_k127_5349402_7	1278073.MYSTI_03953	4.129e-102	348.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria,2YUM5@29|Myxococcales	28221|Deltaproteobacteria	E	Sarcosine oxidase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
DYD1_k127_5349402_39	589924.Ferp_2558	8.236e-18	94.0	COG0446@1|root,arCOG05745@2157|Archaea,2XZPN@28890|Euryarchaeota,246DF@183980|Archaeoglobi	183980|Archaeoglobi	C	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
DYD1_k127_5349402_15	565033.GACE_0620	2.008e-62	237.0	COG0446@1|root,arCOG01294@2157|Archaea,2XUFI@28890|Euryarchaeota,246RK@183980|Archaeoglobi	183980|Archaeoglobi	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Pyr_redox_2
DYD1_k127_5349402_45	691883.XP_009493385.1	8.819e-09	65.0	COG1051@1|root,2S8UU@2759|Eukaryota	2759|Eukaryota	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DYD1_k127_5349402_43	348780.NP_0674A	6.07e-11	66.0	COG0640@1|root,arCOG00394@2157|Archaea,2XYXY@28890|Euryarchaeota,23WW0@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_5349402_49	1123288.SOV_4c06340	3.354e-06	55.0	2EKB5@1|root,33E1I@2|Bacteria,1VFSV@1239|Firmicutes,4H8IH@909932|Negativicutes	909932|Negativicutes	S	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
DYD1_k127_5349402_42	368407.Memar_0431	3.57e-12	78.0	COG1719@1|root,arCOG01688@2157|Archaea,2XYSH@28890|Euryarchaeota	28890|Euryarchaeota	K	4-vinyl reductase, 4VR	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	DUF2507,HTH_5,V4R
DYD1_k127_5349402_37	1230457.C476_13787	1.814e-19	104.0	COG1033@1|root,arCOG02174@2157|Archaea,2XT5A@28890|Euryarchaeota,23SV0@183963|Halobacteria	183963|Halobacteria	L	exporters of the RND superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
DYD1_k127_5349402_48	326427.Cagg_1833	1.844e-07	59.0	COG3241@1|root,COG3241@2|Bacteria	2|Bacteria	C	Transfers electrons from cytochrome c551 to cytochrome oxidase	azu	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009767,GO:0009987,GO:0015979,GO:0016020,GO:0019684,GO:0022900,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0055114,GO:0071944	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD1_k127_5349402_51	1245469.S58_42860	4.264e-05	58.0	COG4675@1|root,COG4675@2|Bacteria,1NHDM@1224|Proteobacteria	1224|Proteobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5349402_46	1353529.M899_2375	5.606e-08	67.0	COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
DYD1_k127_5349402_23	246969.TAM4_213	2.135e-48	195.0	COG0457@1|root,COG1672@1|root,arCOG03045@2157|Archaea,arCOG03169@2157|Archaea,2Y7QE@28890|Euryarchaeota,245KV@183968|Thermococci	183968|Thermococci	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5349402_6	443143.GM18_2592	1.051e-111	380.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
DYD1_k127_5349402_0	269797.Mbar_A1593	5.109e-196	634.0	COG1241@1|root,arCOG00439@2157|Archaea,2XT5D@28890|Euryarchaeota,2N9E6@224756|Methanomicrobia	224756|Methanomicrobia	L	Belongs to the MCM family	mcm	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_N,MCM_OB
DYD1_k127_5349402_34	1151117.AJLF01000001_gene1702	5.133e-24	104.0	COG2412@1|root,arCOG04051@2157|Archaea,2XYQK@28890|Euryarchaeota,244B2@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
DYD1_k127_5349402_25	1094980.Mpsy_2885	1.517e-46	181.0	COG1499@1|root,arCOG04149@2157|Archaea,2XUAI@28890|Euryarchaeota,2N9GP@224756|Methanomicrobia	224756|Methanomicrobia	J	pfam nmd3	-	-	-	ko:K07562	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko03009	-	-	-	NMD3
DYD1_k127_5349402_47	1156937.MFUM_700084	7.956e-08	58.0	COG1826@1|root,COG1826@2|Bacteria,46X58@74201|Verrucomicrobia,37HC0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	mttA/Hcf106 family	-	-	-	-	-	-	-	-	-	-	-	-	MttA_Hcf106
DYD1_k127_541428_0	1211777.BN77_p10748	2.489e-82	287.0	COG1835@1|root,COG1835@2|Bacteria,1PVUR@1224|Proteobacteria,2TTRB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
DYD1_k127_5423583_2	1148.1652441	5.878e-16	83.0	COG3293@1|root,COG3293@2|Bacteria,1G8RQ@1117|Cyanobacteria,1H6T1@1142|Synechocystis	1117|Cyanobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DUF4096
DYD1_k127_5423583_0	349521.HCH_02566	3.175e-61	222.0	COG3293@1|root,COG3293@2|Bacteria,1R5NV@1224|Proteobacteria,1SZ5P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
DYD1_k127_5423583_1	1123508.JH636443_gene5134	6.445e-24	104.0	2E296@1|root,32XEW@2|Bacteria,2J070@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5442902_7	414684.RC1_2620	9.954e-08	62.0	COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,2TU8G@28211|Alphaproteobacteria,2JTBJ@204441|Rhodospirillales	204441|Rhodospirillales	O	Pyroglutamyl peptidase	-	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
DYD1_k127_5442902_5	1415780.JPOG01000001_gene1140	1.939e-12	78.0	2C75R@1|root,2ZCK5@2|Bacteria,1NMP7@1224|Proteobacteria,1SHMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
DYD1_k127_5442902_0	471853.Bcav_3496	3.706e-51	194.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
DYD1_k127_5442902_2	1127131.WEISSC39_09265	2.547e-29	123.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,4AZ4C@81850|Leuconostocaceae	91061|Bacilli	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DYD1_k127_5442902_6	158189.SpiBuddy_2107	7.284e-10	70.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
DYD1_k127_5442902_4	65393.PCC7424_3291	1.481e-12	78.0	COG2267@1|root,COG2267@2|Bacteria,1GHTC@1117|Cyanobacteria,3KJIN@43988|Cyanothece	1117|Cyanobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DYD1_k127_5442902_3	1293054.HSACCH_00288	1.621e-23	114.0	2ACGP@1|root,3122D@2|Bacteria,1V5NE@1239|Firmicutes,24J4I@186801|Clostridia,3WBNQ@53433|Halanaerobiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5442902_1	880072.Desac_0390	3.442e-38	151.0	COG4122@1|root,COG4122@2|Bacteria,1R4VI@1224|Proteobacteria,42VVN@68525|delta/epsilon subdivisions,2WRTH@28221|Deltaproteobacteria,2MS9X@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
DYD1_k127_5442902_8	91464.S7335_1502	2.501e-06	53.0	COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,1H46I@1129|Synechococcus	1117|Cyanobacteria	Q	Q COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
DYD1_k127_5481360_0	1340493.JNIF01000003_gene2420	5.29e-08	66.0	2DP40@1|root,330F7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5527339_2	661478.OP10G_0951	1.162e-12	76.0	COG1520@1|root,COG2319@1|root,COG1520@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	KAP_NTPase,WD40
DYD1_k127_5527339_3	5808.XP_002140747.1	0.000132	48.0	2E59E@1|root,2SC3H@2759|Eukaryota,3YC2B@5794|Apicomplexa,3YPK6@5796|Coccidia	5794|Apicomplexa	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5527339_1	868131.MSWAN_0394	3.118e-53	195.0	COG0080@1|root,arCOG04372@2157|Archaea,2XTJN@28890|Euryarchaeota,23NZG@183925|Methanobacteria	183925|Methanobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rpl11	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DYD1_k127_5527339_0	1128421.JAGA01000002_gene1359	7.022e-60	223.0	COG0520@1|root,COG0520@2|Bacteria,2NP4B@2323|unclassified Bacteria	2|Bacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DYD1_k127_5527339_4	1458357.BG58_41655	0.0004057	51.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,2VSG0@28216|Betaproteobacteria,1K387@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM ThiJ PfpI domain protein	-	-	4.2.1.103	ko:K18199	ko00930,map00930	-	R05771	RC01467	ko00000,ko00001,ko01000,ko01002	-	-	-	DJ-1_PfpI
DYD1_k127_5552162_1	204669.Acid345_1471	3.267e-07	55.0	COG3167@1|root,COG3167@2|Bacteria	2|Bacteria	NU	carbon utilization	mshJ	-	-	ko:K02664,ko:K02665,ko:K12280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO,T2SSM,T2SSM_b
DYD1_k127_5602276_0	1123487.KB892844_gene853	2.085e-05	49.0	2EPCF@1|root,33GZ4@2|Bacteria,1NMQU@1224|Proteobacteria,2VY4J@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5679740_51	575540.Isop_1191	1.817e-05	49.0	COG3118@1|root,COG3118@2|Bacteria,2J53R@203682|Planctomycetes	203682|Planctomycetes	O	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
DYD1_k127_5679740_42	479435.Kfla_3911	5.176e-13	70.0	COG3576@1|root,COG3576@2|Bacteria,2GP9M@201174|Actinobacteria,4DVY0@85009|Propionibacteriales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
DYD1_k127_5679740_9	1521187.JPIM01000050_gene3431	3.264e-103	358.0	COG3975@1|root,COG3975@2|Bacteria,2GAB7@200795|Chloroflexi,374W2@32061|Chloroflexia	32061|Chloroflexia	S	SMART PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
DYD1_k127_5679740_55	690585.JNNU01000028_gene2321	0.0002502	51.0	COG0558@1|root,COG0558@2|Bacteria,1N1AE@1224|Proteobacteria,2UCWB@28211|Alphaproteobacteria,4B981@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
DYD1_k127_5679740_37	709986.Deima_0076	5.967e-19	97.0	COG0584@1|root,COG0584@2|Bacteria,1WK5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DYD1_k127_5679740_24	1220582.RRU01S_07_04060	3.888e-33	141.0	COG3741@1|root,COG3741@2|Bacteria,1RG2S@1224|Proteobacteria,2U8RG@28211|Alphaproteobacteria,4BB3K@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
DYD1_k127_5679740_23	234267.Acid_1308	1.46e-42	175.0	COG2308@1|root,COG2308@2|Bacteria,3Y6VU@57723|Acidobacteria	57723|Acidobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5679740_30	909613.UO65_0827	2.354e-23	109.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
DYD1_k127_5679740_39	693746.OBV_25690	3.378e-17	96.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,2N81X@216572|Oscillospiraceae	186801|Clostridia	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DYD1_k127_5679740_32	935837.JAEK01000040_gene3713	1.173e-21	109.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus	91061|Bacilli	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
DYD1_k127_5679740_17	211165.AJLN01000039_gene1896	6.281e-53	198.0	COG0385@1|root,COG0385@2|Bacteria,1G2W8@1117|Cyanobacteria,1JJ6Q@1189|Stigonemataceae	1117|Cyanobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
DYD1_k127_5679740_54	351160.RRC454	0.000135	51.0	COG1241@1|root,arCOG02259@2157|Archaea,2Y283@28890|Euryarchaeota,2NA4Q@224756|Methanomicrobia	224756|Methanomicrobia	L	DNA replication initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5679740_3	439481.Aboo_0942	1.05e-188	611.0	COG0532@1|root,arCOG01560@2157|Archaea,2XU09@28890|Euryarchaeota,3F2FJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D4,IF-2,Intein_splicing,LAGLIDADG_3
DYD1_k127_5679740_53	335543.Sfum_3494	5.925e-05	55.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DYD1_k127_5679740_11	751944.HALDL1_08030	3.939e-73	259.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,23TIU@183963|Halobacteria	183963|Halobacteria	E	COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DYD1_k127_5679740_18	754476.Q7A_2508	2.284e-51	205.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,46014@72273|Thiotrichales	72273|Thiotrichales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DYD1_k127_5679740_43	429009.Adeg_1599	1.03e-12	80.0	COG1322@1|root,COG1322@2|Bacteria	2|Bacteria	S	DNA recombination	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	Apolipoprotein,RmuC
DYD1_k127_5679740_46	673860.AciM339_0088	1.932e-09	63.0	arCOG06692@1|root,arCOG06692@2157|Archaea,2Y53M@28890|Euryarchaeota,3F3HV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5679740_5	1343739.PAP_08180	1.82e-142	466.0	COG0436@1|root,arCOG01131@2157|Archaea,2XVXM@28890|Euryarchaeota,243JD@183968|Thermococci	183968|Thermococci	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
DYD1_k127_5679740_35	644281.MFS40622_0911	1.167e-19	90.0	arCOG03086@1|root,arCOG03086@2157|Archaea,2Y1GM@28890|Euryarchaeota	28890|Euryarchaeota	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
DYD1_k127_5679740_33	593750.Metfor_1990	4.043e-21	94.0	COG1598@1|root,arCOG02412@2157|Archaea,2Y1KY@28890|Euryarchaeota,2NB5X@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5679740_12	3055.EDP07936	1.619e-70	243.0	COG0225@1|root,KOG1635@2759|Eukaryota,380HK@33090|Viridiplantae,34MJ2@3041|Chlorophyta	3041|Chlorophyta	O	methionine sulfoxide reductase	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DYD1_k127_5679740_21	1033802.SSPSH_002148	4.622e-43	174.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
DYD1_k127_5679740_8	797114.C475_04401	5.532e-125	422.0	COG0471@1|root,arCOG00237@2157|Archaea,2XSW7@28890|Euryarchaeota,23SDG@183963|Halobacteria	183963|Halobacteria	P	COG0471 Di- and tricarboxylate transporters	nso	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
DYD1_k127_5679740_44	522373.Smlt1324	6.739e-11	72.0	2AKRW@1|root,31BIT@2|Bacteria,1RK6Q@1224|Proteobacteria,1S7DH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5679740_28	224325.AF_1681	1.809e-25	117.0	arCOG08622@1|root,arCOG08622@2157|Archaea	2157|Archaea	S	Family of unknown function (DUF5343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5343
DYD1_k127_5679740_50	595460.RRSWK_03767	1.245e-05	54.0	COG1733@1|root,COG1733@2|Bacteria,2J0R4@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_5679740_22	693661.Arcve_1149	7.668e-43	174.0	COG1721@1|root,arCOG02742@2157|Archaea,2Y7CK@28890|Euryarchaeota,246B6@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DYD1_k127_5679740_7	401526.TcarDRAFT_1353	1.457e-128	426.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H24N@909932|Negativicutes	909932|Negativicutes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DYD1_k127_5679740_25	521045.Kole_1745	6.63e-33	133.0	COG1047@1|root,COG1047@2|Bacteria,2GD8F@200918|Thermotogae	200918|Thermotogae	G	peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
DYD1_k127_5679740_16	1227457.C451_06972	3.92e-58	210.0	COG0013@1|root,arCOG01254@2157|Archaea,2XTZC@28890|Euryarchaeota,23UTP@183963|Halobacteria	183963|Halobacteria	J	metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
DYD1_k127_5679740_56	518766.Rmar_1750	0.0005982	52.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4P230@976|Bacteroidetes	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec
DYD1_k127_5679740_41	316274.Haur_4084	7.69e-16	92.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
DYD1_k127_5679740_31	186497.PF0315	7.77e-22	111.0	COG1772@1|root,arCOG04364@2157|Archaea,2XXJ6@28890|Euryarchaeota,243JJ@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF531)	-	-	-	ko:K09725	-	-	-	-	ko00000	-	-	-	DUF531
DYD1_k127_5679740_47	991905.SL003B_2011	2.825e-09	69.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,2TRRW@28211|Alphaproteobacteria,4BRHA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Threonyl and Alanyl tRNA synthetase second additional domain	alaS2	GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
DYD1_k127_5679740_27	1437824.BN940_07791	1.312e-26	117.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VW5P@28216|Betaproteobacteria,3T968@506|Alcaligenaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF454)	ybaN	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
DYD1_k127_5679740_29	1244869.H261_14580	5.531e-25	114.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2VGB4@28211|Alphaproteobacteria,2JS51@204441|Rhodospirillales	204441|Rhodospirillales	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
DYD1_k127_5679740_26	1122164.JHWF01000006_gene220	1.971e-27	128.0	COG0508@1|root,COG0508@2|Bacteria,1QBDH@1224|Proteobacteria,1T6YI@1236|Gammaproteobacteria,1JDME@118969|Legionellales	118969|Legionellales	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
DYD1_k127_5679740_0	264462.Bd2784	0.0	1019.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2MTH2@213481|Bdellovibrionales,2WIIV@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	aconitate hydratase	aco	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DYD1_k127_5679740_48	1333523.L593_02375	4.525e-08	64.0	COG3291@1|root,arCOG03509@1|root,arCOG02546@2157|Archaea,arCOG03509@2157|Archaea,2Y7ZF@28890|Euryarchaeota,24143@183963|Halobacteria	183963|Halobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
DYD1_k127_5679740_45	1333523.L593_10660	1.686e-09	68.0	COG3291@1|root,COG3325@1|root,arCOG02546@2157|Archaea,arCOG07840@2157|Archaea,2Y7YU@28890|Euryarchaeota,241E0@183963|Halobacteria	183963|Halobacteria	G	chitinase	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,PKD
DYD1_k127_5679740_15	400682.PAC_15723904	9.479e-62	228.0	COG0179@1|root,KOG1535@2759|Eukaryota,39TDF@33154|Opisthokonta,3BGYJ@33208|Metazoa	33208|Metazoa	Q	acylpyruvate hydrolase activity	FAHD1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008948,GO:0009060,GO:0009987,GO:0015980,GO:0016787,GO:0016822,GO:0016823,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0018773,GO:0019752,GO:0031974,GO:0031981,GO:0034545,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0055114,GO:0070013,GO:0071704,GO:0072350	3.7.1.5	ko:K01557	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
DYD1_k127_5679740_2	518766.Rmar_1401	3.351e-204	642.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,1FJ4C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DYD1_k127_5679740_6	518766.Rmar_2528	1.295e-128	426.0	COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,1FJ27@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	PFAM Rh family protein ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
DYD1_k127_5679740_13	693661.Arcve_1885	1.639e-70	250.0	COG0039@1|root,arCOG00246@2157|Archaea,2XTQ0@28890|Euryarchaeota,245VI@183980|Archaeoglobi	183980|Archaeoglobi	C	Belongs to the LDH MDH superfamily	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DYD1_k127_5679740_20	673860.AciM339_0726	1.11e-50	194.0	COG1184@1|root,arCOG01124@2157|Archaea,2XUFM@28890|Euryarchaeota,3F2H6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eIF-2B alpha beta delta subunits family	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.29	ko:K18237	-	-	-	-	ko00000,ko01000	-	-	-	IF-2B
DYD1_k127_5679740_4	673860.AciM339_0725	1.28e-148	488.0	COG0213@1|root,arCOG02013@2157|Archaea,2XT19@28890|Euryarchaeota,3F2H9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO	deoA	GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576	2.4.2.57	ko:K18931	-	-	R10836,R10837,R10838	RC00063	ko00000,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,Molydop_binding,PYNP_C
DYD1_k127_5679740_34	1286171.EAL2_c17470	1.238e-20	102.0	COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,24IF0@186801|Clostridia	186801|Clostridia	S	Snare associated golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DYD1_k127_5679740_36	446468.Ndas_1708	1.923e-19	99.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4EIRX@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DYD1_k127_5679740_40	4096.XP_009799025.1	7.276e-17	89.0	28JQN@1|root,2QS3Z@2759|Eukaryota,37K92@33090|Viridiplantae,3G9HQ@35493|Streptophyta,44R1F@71274|asterids	35493|Streptophyta	S	Protein of unknown function, DUF599	-	-	-	-	-	-	-	-	-	-	-	-	DUF599
DYD1_k127_5679740_49	1227457.C451_14275	5.418e-06	57.0	COG0589@1|root,arCOG02053@2157|Archaea,2XXRS@28890|Euryarchaeota,23W7D@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD1_k127_5679740_10	156889.Mmc1_1697	5.962e-74	271.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2TU0C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	ko:K03319,ko:K09477,ko:K11106,ko:K14445	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.47,2.A.47.1,2.A.47.3.2,2.A.47.3.3	-	-	Na_sulph_symp
DYD1_k127_5679740_52	1298593.TOL_0671	4.477e-05	55.0	COG3343@1|root,COG3343@2|Bacteria,1QX02@1224|Proteobacteria	1224|Proteobacteria	K	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5679740_57	797114.C475_01951	0.0008329	48.0	COG1572@1|root,arCOG07561@1|root,arCOG02532@2157|Archaea,arCOG07561@2157|Archaea,2XZY0@28890|Euryarchaeota	28890|Euryarchaeota	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD
DYD1_k127_5679740_19	192952.MM_1616	6.258e-51	192.0	COG1691@1|root,arCOG02465@2157|Archaea,2XTIH@28890|Euryarchaeota,2N9MD@224756|Methanomicrobia	224756|Methanomicrobia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
DYD1_k127_5679740_38	358396.C445_20510	1.428e-17	93.0	COG1340@1|root,arCOG01159@2157|Archaea,2XU21@28890|Euryarchaeota,23T32@183963|Halobacteria	183963|Halobacteria	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5679740_14	1003195.SCAT_5790	7.258e-64	231.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
DYD1_k127_5679740_1	552811.Dehly_1052	1.683e-243	771.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,34CU7@301297|Dehalococcoidia	301297|Dehalococcoidia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DYD1_k127_568021_3	742738.HMPREF9460_02160	0.0001597	52.0	COG1961@1|root,COG1961@2|Bacteria,1TP0S@1239|Firmicutes,24A9P@186801|Clostridia,26ASZ@186813|unclassified Clostridiales	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
DYD1_k127_568021_1	717785.HYPMC_1209	1.047e-17	88.0	2EC8I@1|root,33670@2|Bacteria,1NH09@1224|Proteobacteria,2UKPS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_568021_2	1121033.AUCF01000021_gene2887	8.418e-10	67.0	COG4627@1|root,COG4627@2|Bacteria,1RKW8@1224|Proteobacteria,2UA2Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DYD1_k127_5696081_6	1123389.ATXJ01000007_gene1770	3.948e-169	550.0	COG0367@1|root,COG0367@2|Bacteria,1WK3V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DYD1_k127_5696081_12	368407.Memar_1605	8.626e-119	391.0	COG0381@1|root,arCOG01392@2157|Archaea,2XU0B@28890|Euryarchaeota,2NANE@224756|Methanomicrobia	224756|Methanomicrobia	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DYD1_k127_5696081_73	439481.Aboo_0241	1.159e-27	126.0	COG0438@1|root,arCOG01410@2157|Archaea,2XYAQ@28890|Euryarchaeota,3F3FW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DYD1_k127_5696081_45	272844.PAB1606	1.275e-52	201.0	COG0438@1|root,arCOG01410@2157|Archaea,2XYAQ@28890|Euryarchaeota,244MP@183968|Thermococci	183968|Thermococci	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
DYD1_k127_5696081_97	1095769.CAHF01000006_gene1863	2.747e-06	59.0	COG0463@1|root,COG0463@2|Bacteria,1QV5U@1224|Proteobacteria,2W2UZ@28216|Betaproteobacteria,4795X@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD1_k127_5696081_29	673860.AciM339_0815	1.536e-68	247.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota	28890|Euryarchaeota	S	Oxidoreductase domain protein	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DYD1_k127_5696081_56	572478.Vdis_2006	5.454e-44	169.0	COG1208@1|root,arCOG00666@2157|Archaea,2XSR2@28889|Crenarchaeota	28889|Crenarchaeota	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DYD1_k127_5696081_18	868131.MSWAN_2076	6.164e-94	323.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,23NU5@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DYD1_k127_5696081_33	1196029.ALIM01000035_gene2278	1.25e-61	231.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,1ZC93@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DYD1_k127_5696081_8	1229909.NSED_08130	5.211e-142	468.0	COG1012@1|root,arCOG01252@2157|Archaea,41T12@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
DYD1_k127_5696081_14	767817.Desgi_2439	3.231e-111	377.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
DYD1_k127_5696081_11	562970.Btus_2368	3.106e-127	419.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DYD1_k127_5696081_102	1382306.JNIM01000001_gene1291	5.459e-05	55.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368,ko:K02638	ko00195,ko00910,ko01120,map00195,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	CHRD,Copper-bind,Cu-oxidase_3,Cupredoxin_1
DYD1_k127_5696081_88	1128421.JAGA01000002_gene1077	3.881e-10	66.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1,DUF4399
DYD1_k127_5696081_26	1168065.DOK_17735	9.271e-71	255.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,DUF2048,Peptidase_S9
DYD1_k127_5696081_40	1254432.SCE1572_33895	1.298e-56	203.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DYD1_k127_5696081_90	1396858.Q666_08580	3.64e-09	68.0	COG1266@1|root,COG1266@2|Bacteria,1R5RA@1224|Proteobacteria,1S0ZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DYD1_k127_5696081_34	700015.Corgl_0087	3.266e-61	216.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CV13@84998|Coriobacteriia	84998|Coriobacteriia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DYD1_k127_5696081_35	1304874.JAFY01000002_gene920	4.01e-61	223.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
DYD1_k127_5696081_94	933115.GPDM_15019	1.451e-07	64.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli,26E03@186818|Planococcaceae	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_5696081_10	1304880.JAGB01000002_gene2025	9.1e-129	427.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DYD1_k127_5696081_89	1286631.X805_30960	4.182e-10	72.0	COG1404@1|root,COG1520@1|root,COG5640@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K14645,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,PQQ_2,Peptidase_S8,SBBP
DYD1_k127_5696081_47	420247.Msm_0725	7.548e-51	196.0	COG0258@1|root,arCOG04050@2157|Archaea,2XTJD@28890|Euryarchaeota,23NWP@183925|Methanobacteria	183925|Methanobacteria	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
DYD1_k127_5696081_23	1071085.KK033114_gene1652	5.518e-83	297.0	COG0608@1|root,arCOG00427@2157|Archaea,2XT8Y@28890|Euryarchaeota,23S1D@183963|Halobacteria	183963|Halobacteria	L	COG0608 Single-stranded DNA-specific exonuclease	recJ1	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
DYD1_k127_5696081_61	1120973.AQXL01000038_gene603	7.333e-38	161.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,2781E@186823|Alicyclobacillaceae	91061|Bacilli	NT	CHASE3 domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
DYD1_k127_5696081_100	1453501.JELR01000002_gene294	4.836e-05	53.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,1S26J@1236|Gammaproteobacteria,466J2@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	CheW protein	cheW	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009605,GO:0009893,GO:0009987,GO:0010604,GO:0016020,GO:0019222,GO:0019904,GO:0023052,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032268,GO:0032270,GO:0032991,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0098561,GO:1901873,GO:1901875	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
DYD1_k127_5696081_25	867903.ThesuDRAFT_00772	8.246e-79	291.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,3WCTV@538999|Clostridiales incertae sedis	186801|Clostridia	NT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	cheA3	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
DYD1_k127_5696081_32	351160.LRC320	2.476e-63	233.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N95K@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_5696081_75	877455.Metbo_1476	1.417e-21	108.0	COG0842@1|root,arCOG01463@2157|Archaea,2XVQJ@28890|Euryarchaeota,23NM6@183925|Methanobacteria	183925|Methanobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DYD1_k127_5696081_62	1114856.C496_04940	2.077e-36	151.0	COG0628@1|root,arCOG02642@2157|Archaea,2XT00@28890|Euryarchaeota,23TDZ@183963|Halobacteria	183963|Halobacteria	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DYD1_k127_5696081_85	515620.EUBELI_20371	1.367e-12	74.0	COG2201@1|root,COG2201@2|Bacteria,1UJY4@1239|Firmicutes	1239|Firmicutes	NT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DYD1_k127_5696081_84	1125863.JAFN01000001_gene2516	1.145e-12	74.0	COG2201@1|root,COG2201@2|Bacteria,1N7FN@1224|Proteobacteria,42V5Y@68525|delta/epsilon subdivisions,2WSBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	cheY44H	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD1_k127_5696081_63	1356854.N007_09340	3.325e-36	142.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,4HGY2@91061|Bacilli,279U5@186823|Alicyclobacillaceae	91061|Bacilli	T	cheY-homologous receiver domain	cheY	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD1_k127_5696081_96	370438.PTH_2063	7.894e-07	59.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,247MX@186801|Clostridia,2620W@186807|Peptococcaceae	186801|Clostridia	NT	Chemotaxis protein CheC, inhibitor of MCP	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
DYD1_k127_5696081_86	523850.TON_0811	1.826e-12	80.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,2440W@183968|Thermococci	28890|Euryarchaeota	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
DYD1_k127_5696081_16	1266914.ATUK01000001_gene761	2.708e-102	352.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWES@135613|Chromatiales	135613|Chromatiales	L	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
DYD1_k127_5696081_28	268739.Nmlp_3254	5.733e-69	245.0	COG1395@1|root,arCOG04152@2157|Archaea,2XTMG@28890|Euryarchaeota,23SJQ@183963|Halobacteria	183963|Halobacteria	K	HTH-type transcriptional regulatory protein	-	-	-	ko:K07728	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
DYD1_k127_5696081_57	523850.TON_1355	5.981e-44	174.0	COG1404@1|root,arCOG00702@2157|Archaea,2XTGN@28890|Euryarchaeota,24359@183968|Thermococci	183968|Thermococci	O	Serine protease with a broad substrate specificity	-	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_S8
DYD1_k127_5696081_101	69014.TK1436	4.963e-05	54.0	COG1543@1|root,arCOG03281@2157|Archaea,2XW5I@28890|Euryarchaeota,24389@183968|Thermococci	183968|Thermococci	G	Belongs to the glycosyl hydrolase 57 family	-	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0030978,GO:0030979,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57,HHH_5
DYD1_k127_5696081_69	1463854.JOHT01000015_gene5296	2.139e-32	137.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DYD1_k127_5696081_36	1184609.KILIM_052_00380	4.15e-60	216.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4F6HH@85018|Dermatophilaceae	201174|Actinobacteria	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DYD1_k127_5696081_92	1519439.JPJG01000055_gene2200	9.813e-09	66.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
DYD1_k127_5696081_68	1237149.C900_01498	8.097e-34	150.0	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,4NDUQ@976|Bacteroidetes,47PTN@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
DYD1_k127_5696081_91	512565.AMIS_65220	5.217e-09	64.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DCNR@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DYD1_k127_5696081_79	396595.TK90_0680	3.858e-17	86.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
DYD1_k127_5696081_104	1227487.C474_11541	0.0001008	54.0	COG1378@1|root,arCOG02037@2157|Archaea,2XVHD@28890|Euryarchaeota,23TCJ@183963|Halobacteria	183963|Halobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
DYD1_k127_5696081_4	439481.Aboo_1131	2.779e-203	647.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,3F2FS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TCP-1/cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
DYD1_k127_5696081_2	439481.Aboo_1131	1.49e-213	677.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,3F2FS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TCP-1/cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
DYD1_k127_5696081_80	387631.Asulf_00223	7.079e-17	94.0	COG4083@1|root,arCOG04471@2157|Archaea,2XTQZ@28890|Euryarchaeota,2464T@183980|Archaeoglobi	183980|Archaeoglobi	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
DYD1_k127_5696081_54	1463845.JOIG01000004_gene4217	6.394e-45	174.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
DYD1_k127_5696081_82	643562.Daes_1913	1.82e-14	83.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2M8CV@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
DYD1_k127_5696081_83	263358.VAB18032_10220	7.959e-13	81.0	COG2234@1|root,COG2234@2|Bacteria,2GIT0@201174|Actinobacteria,4DB2F@85008|Micromonosporales	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DYD1_k127_5696081_65	1123319.AUBE01000015_gene5674	2.976e-35	151.0	2AQV1@1|root,31G37@2|Bacteria,2IEU1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DYD1_k127_5696081_9	1125863.JAFN01000001_gene1833	2.664e-137	453.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
DYD1_k127_5696081_99	268739.Nmlp_2313	4.216e-05	55.0	COG3398@1|root,arCOG02611@2157|Archaea,2XX30@28890|Euryarchaeota,23VMW@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
DYD1_k127_5696081_0	690850.Desaf_0454	2.383e-234	740.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WJ61@28221|Deltaproteobacteria,2M9DR@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	ABC transporter, transmembrane	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
DYD1_k127_5696081_77	671143.DAMO_0317	5.342e-19	102.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,CBM_35,DUF1080,PKD
DYD1_k127_5696081_37	1227454.C446_00435	2.961e-59	224.0	COG0697@1|root,arCOG00271@2157|Archaea,2XTD0@28890|Euryarchaeota,23TNI@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_5696081_66	348780.NP_4198A	1.001e-34	139.0	COG0110@1|root,arCOG01850@2157|Archaea,2XWH3@28890|Euryarchaeota,23V5N@183963|Halobacteria	183963|Halobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	yvoF	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
DYD1_k127_5696081_95	717606.PaecuDRAFT_3249	2.019e-07	62.0	COG4347@1|root,COG4347@2|Bacteria,1V1NI@1239|Firmicutes,4HFTW@91061|Bacilli,26X54@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1405)	ypjA	-	-	-	-	-	-	-	-	-	-	-	DUF1405
DYD1_k127_5696081_107	368407.Memar_2009	0.0008038	46.0	COG4004@1|root,arCOG04412@2157|Archaea,2Y1TD@28890|Euryarchaeota,2NBJH@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5696081_71	268739.Nmlp_2582	2.886e-31	144.0	arCOG00805@1|root,arCOG00805@2157|Archaea,2XVHZ@28890|Euryarchaeota,23UP7@183963|Halobacteria	183963|Halobacteria	L	COG3857 ATP-dependent nuclease, subunit B	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
DYD1_k127_5696081_20	358396.C445_17179	6.582e-87	327.0	COG0210@1|root,arCOG00802@2157|Archaea,2XSUQ@28890|Euryarchaeota,23T4C@183963|Halobacteria	183963|Halobacteria	L	COG0210 Superfamily I DNA and RNA helicases	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
DYD1_k127_5696081_30	70448.A0A090M2Z3	1.683e-68	265.0	COG1112@1|root,KOG1803@2759|Eukaryota,37P7D@33090|Viridiplantae,34HHA@3041|Chlorophyta	3041|Chlorophyta	L	AAA domain	-	-	3.6.4.12,3.6.4.13	ko:K19036	-	-	-	-	ko00000,ko01000,ko03009,ko03012	-	-	-	AAA_11,AAA_12,R3H
DYD1_k127_5696081_98	1280380.KR100_07855	1.728e-05	57.0	COG1345@1|root,COG4886@1|root,COG5276@1|root,COG1345@2|Bacteria,COG4886@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K02396,ko:K13735,ko:K21449	ko02040,ko05100,map02040,map05100	-	-	-	ko00000,ko00001,ko02000,ko02035	1.B.40.2	-	-	BACON,CHU_C,LRR_5
DYD1_k127_5696081_93	797302.Halru_0218	3.844e-08	66.0	COG5276@1|root,arCOG02565@2157|Archaea,2XUGK@28890|Euryarchaeota,23TB8@183963|Halobacteria	183963|Halobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_5696081_74	1131266.ARWQ01000001_gene1113	4.189e-25	118.0	COG3359@1|root,arCOG03130@2157|Archaea,41STU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H_2
DYD1_k127_5696081_22	1197130.BAFM01000003_gene623	4.742e-85	296.0	COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,23SJH@183963|Halobacteria	183963|Halobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DYD1_k127_5696081_31	868131.MSWAN_1950	3.019e-65	245.0	COG0595@1|root,arCOG00547@2157|Archaea,2XTIB@28890|Euryarchaeota,23PHA@183925|Methanobacteria	183925|Methanobacteria	J	PFAM RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B_2,RMMBL
DYD1_k127_5696081_106	59919.PMM0367	0.0002769	49.0	COG1359@1|root,COG1359@2|Bacteria,1GE66@1117|Cyanobacteria,1MMMD@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	ABM
DYD1_k127_5696081_46	1449080.JQMV01000003_gene887	6.161e-52	194.0	COG2185@1|root,COG2185@2|Bacteria,1WJS8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM methylmalonyl-CoA mutase C-terminal domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
DYD1_k127_5696081_70	314285.KT71_03617	1.084e-31	136.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,1SZRM@1236|Gammaproteobacteria,1J6VZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Molybdopterin-biosynthesis enzyme	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
DYD1_k127_5696081_44	1234364.AMSF01000024_gene3814	4.689e-53	197.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1X4FR@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
DYD1_k127_5696081_87	1459636.NTE_00031	1.92e-10	67.0	COG0864@1|root,arCOG01008@2157|Archaea,41SQM@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
DYD1_k127_5696081_50	1118054.CAGW01000018_gene4236	2.386e-48	185.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,26RT6@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
DYD1_k127_5696081_41	1304874.JAFY01000002_gene189	2.452e-56	212.0	COG1121@1|root,COG1121@2|Bacteria,3TASJ@508458|Synergistetes	508458|Synergistetes	P	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
DYD1_k127_5696081_60	1237500.ANBA01000009_gene1397	4.505e-39	157.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4EI6R@85012|Streptosporangiales	201174|Actinobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
DYD1_k127_5696081_72	1123368.AUIS01000008_gene2270	6.66e-31	126.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1S73Y@1236|Gammaproteobacteria,2NDSR@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
DYD1_k127_5696081_52	1123237.Salmuc_01626	8.411e-48	191.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2U3FU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
DYD1_k127_5696081_51	1324957.K933_12947	5.098e-48	191.0	arCOG02771@1|root,arCOG02771@2157|Archaea,2XU3G@28890|Euryarchaeota,23SGX@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5696081_58	1120956.JHZK01000024_gene1085	1.799e-41	163.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,1JNDJ@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Cytochrome c oxidase subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
DYD1_k127_5696081_5	1238182.C882_3839	1.909e-172	557.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2JPCV@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DYD1_k127_5696081_76	1382356.JQMP01000004_gene54	4.171e-21	107.0	COG1622@1|root,COG1622@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
DYD1_k127_5696081_103	1128912.GMES_0793	8.495e-05	50.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,1SG0D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	universal stress protein	-	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
DYD1_k127_5696081_59	584708.Apau_2183	5.508e-40	156.0	COG0139@1|root,COG0139@2|Bacteria,3TASS@508458|Synergistetes	508458|Synergistetes	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
DYD1_k127_5696081_17	1121921.KB898712_gene2184	2.269e-101	339.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,2PMY6@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Histidine biosynthesis protein	hisF	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	-	ko:K01663,ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iYL1228.KPN_02481	His_biosynth
DYD1_k127_5696081_53	1054217.TALC_00545	3.984e-46	174.0	COG0131@1|root,arCOG04398@2157|Archaea,2XT2K@28890|Euryarchaeota,242GZ@183967|Thermoplasmata	183967|Thermoplasmata	E	Imidazoleglycerol-phosphate dehydratase	-	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
DYD1_k127_5696081_43	378806.STAUR_4682	4.428e-54	203.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2WK1K@28221|Deltaproteobacteria,2YVBU@29|Myxococcales	28221|Deltaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0388	His_biosynth
DYD1_k127_5696081_48	546271.Selsp_1133	1.497e-49	185.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4H3NT@909932|Negativicutes	909932|Negativicutes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DYD1_k127_5696081_38	1054217.TALC_00550	1.069e-58	218.0	COG0079@1|root,arCOG04273@2157|Archaea,2XTFZ@28890|Euryarchaeota,242D6@183967|Thermoplasmata	183967|Thermoplasmata	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DYD1_k127_5696081_21	1220534.B655_1543	2.164e-85	299.0	COG0141@1|root,arCOG04352@2157|Archaea,2XT6M@28890|Euryarchaeota,23NVT@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
DYD1_k127_5696081_24	1379270.AUXF01000002_gene1409	2.972e-82	283.0	COG0040@1|root,COG0040@2|Bacteria,1ZSZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
DYD1_k127_5696081_19	1146883.BLASA_1782	1.291e-89	322.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
DYD1_k127_5696081_67	1173028.ANKO01000208_gene5102	1.251e-34	136.0	COG0745@1|root,COG0745@2|Bacteria,1G5ZH@1117|Cyanobacteria,1HHCH@1150|Oscillatoriales	1117|Cyanobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DYD1_k127_5696081_39	1146883.BLASA_1780	1.944e-57	224.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3,2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K07676,ko:K10715,ko:K20976	ko00230,ko02020,ko02024,ko02025,ko02026,ko04112,ko04113,ko04213,map00230,map02020,map02024,map02025,map02026,map04112,map04113,map04213	M00474,M00511,M00517,M00695,M00820	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg,Trans_reg_C
DYD1_k127_5696081_64	1146883.BLASA_1779	2.467e-35	149.0	COG1413@1|root,COG1413@2|Bacteria,2IHYB@201174|Actinobacteria	201174|Actinobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DYD1_k127_5696081_7	1146883.BLASA_1778	2.829e-151	492.0	COG1215@1|root,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,4EVYU@85013|Frankiales	201174|Actinobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
DYD1_k127_5696081_27	240015.ACP_1013	2.356e-70	250.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DYD1_k127_5696081_3	1449063.JMLS01000013_gene6034	1.169e-212	684.0	COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,4HACN@91061|Bacilli,26QWB@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5696081_81	1121459.AQXE01000002_gene1216	1.644e-16	84.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,42W97@68525|delta/epsilon subdivisions,2WS2D@28221|Deltaproteobacteria,2MCB2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
DYD1_k127_5696081_1	592027.CLG_B0638	8.166e-225	713.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,36DJ7@31979|Clostridiaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DYD1_k127_5696081_49	589924.Ferp_0234	1.22e-48	196.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2478R@183980|Archaeoglobi	28890|Euryarchaeota	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
DYD1_k127_5696081_78	696369.KI912183_gene91	6.108e-19	95.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,26214@186807|Peptococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DYD1_k127_5696081_105	1123508.JH636445_gene6754	0.0001036	52.0	COG0693@1|root,COG0693@2|Bacteria,2IYYE@203682|Planctomycetes	203682|Planctomycetes	S	intracellular protease	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
DYD1_k127_5696081_15	574087.Acear_0620	2.701e-105	361.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DYD1_k127_5696081_13	316274.Haur_1692	1.779e-111	382.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,376IG@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1,6.2.1.3,6.2.1.48	ko:K01897,ko:K02182,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DYD1_k127_5696081_42	1501230.ET33_03120	1.878e-54	201.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,274F6@186822|Paenibacillaceae	91061|Bacilli	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
DYD1_k127_5696081_55	1157638.KB892206_gene7067	1.058e-44	176.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	hmuU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
DYD1_k127_5751039_13	351746.Pput_0693	1.744e-71	256.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	mdeA	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
DYD1_k127_5751039_46	1502724.FF80_00118	7.852e-11	70.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3N80K@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K10126	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DYD1_k127_5751039_3	679926.Mpet_0738	9.588e-130	434.0	COG1384@1|root,arCOG00485@2157|Archaea,2XTR5@28890|Euryarchaeota,2N9FV@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
DYD1_k127_5751039_2	273068.TTE2389	9.401e-173	557.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DYD1_k127_5751039_10	316274.Haur_3189	2.54e-83	289.0	COG2301@1|root,COG2301@2|Bacteria,2G6EA@200795|Chloroflexi,375UN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the HpcH HpaI aldolase family	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
DYD1_k127_5751039_38	977880.RALTA_B1741	7.679e-28	122.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2VTK0@28216|Betaproteobacteria,1K2IK@119060|Burkholderiaceae	28216|Betaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
DYD1_k127_5751039_6	1267005.KB911256_gene1461	5.541e-111	374.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR78@28211|Alphaproteobacteria,3N6XV@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	PFAM acyl-CoA dehydrogenase	mcd	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_5751039_28	1280946.HY29_01305	3.318e-39	151.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2USE6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
DYD1_k127_5751039_11	404589.Anae109_2774	7.222e-79	276.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
DYD1_k127_5751039_33	644282.Deba_2146	7.238e-34	144.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42PK4@68525|delta/epsilon subdivisions,2WM1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
DYD1_k127_5751039_48	589924.Ferp_0866	1.167e-09	65.0	arCOG07522@1|root,arCOG07522@2157|Archaea,2Y1I3@28890|Euryarchaeota,247FV@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5751039_27	1459636.NTE_00462	1.352e-39	156.0	COG0455@1|root,arCOG00589@2157|Archaea	2157|Archaea	D	COG0455 ATPases involved in chromosome partitioning	-	-	-	ko:K03496,ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
DYD1_k127_5751039_7	1340493.JNIF01000004_gene336	1.401e-95	323.0	COG0010@1|root,COG0010@2|Bacteria,3Y5KF@57723|Acidobacteria	57723|Acidobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
DYD1_k127_5751039_26	443144.GM21_0571	1.218e-40	158.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
DYD1_k127_5751039_9	264462.Bd1317	1.024e-87	297.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,42KZX@68525|delta/epsilon subdivisions,2MTRC@213481|Bdellovibrionales,2WM2N@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
DYD1_k127_5751039_1	292459.STH1186	1.413e-231	733.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia	186801|Clostridia	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DYD1_k127_5751039_16	266117.Rxyl_0145	4.693e-69	246.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
DYD1_k127_5751039_0	867845.KI911784_gene3213	2.745e-275	873.0	COG0243@1|root,COG0243@2|Bacteria,2G7V5@200795|Chloroflexi,375JH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
DYD1_k127_5751039_52	298655.KI912266_gene511	1.644e-05	57.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DYD1_k127_5751039_4	1121405.dsmv_3828	7.355e-126	426.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2MJ1A@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157,1.1.1.35,4.2.1.17	ko:K00074,ko:K15016	ko00360,ko00362,ko00650,ko00720,ko01100,ko01120,ko01200,map00360,map00362,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R01975,R01976,R03026,R05576,R06941	RC00029,RC00117,RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N
DYD1_k127_5751039_21	1259795.ARJK01000003_gene978	2.501e-43	172.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,42FN3@68295|Thermoanaerobacterales	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DYD1_k127_5751039_15	224325.AF_0525	8.258e-70	247.0	COG2047@1|root,arCOG00348@2157|Archaea,2XSX4@28890|Euryarchaeota,2463Z@183980|Archaeoglobi	183980|Archaeoglobi	S	PAC2 family	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
DYD1_k127_5751039_45	69014.TK1101	4.216e-12	68.0	COG2260@1|root,arCOG00906@2157|Archaea,2Y1HX@28890|Euryarchaeota,244PG@183968|Thermococci	183968|Thermococci	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
DYD1_k127_5751039_8	673860.AciM339_1479	6.36e-88	298.0	COG1093@1|root,arCOG04107@2157|Archaea,2XTV0@28890|Euryarchaeota,3F2GS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2a	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
DYD1_k127_5751039_50	933801.Ahos_1251	5.374e-07	55.0	COG2051@1|root,arCOG04108@2157|Archaea,2XR0Y@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM ribosomal protein	rps27e	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
DYD1_k127_5751039_30	1054217.TALC_00297	1.098e-37	143.0	COG1631@1|root,arCOG04109@2157|Archaea,2XXV3@28890|Euryarchaeota,241RG@183967|Thermoplasmata	183967|Thermoplasmata	J	Binds to the 23S rRNA	rpl44e	-	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
DYD1_k127_5751039_22	1163617.SCD_n02575	4.738e-42	155.0	2E4PM@1|root,32P93@2|Bacteria,1N4SK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5751039_49	1249480.B649_04570	4.794e-09	64.0	2E4PM@1|root,32P93@2|Bacteria,1N4SK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5751039_17	351160.LRC299	1.304e-67	246.0	COG1467@1|root,arCOG04110@2157|Archaea,2XUZF@28890|Euryarchaeota,2N95F@224756|Methanomicrobia	224756|Methanomicrobia	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	-	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
DYD1_k127_5751039_18	1041930.Mtc_2135	1.954e-55	209.0	COG2219@1|root,arCOG03013@2157|Archaea,2XTDT@28890|Euryarchaeota,2N9HY@224756|Methanomicrobia	224756|Methanomicrobia	L	Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priL	-	-	ko:K18882	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_lrg
DYD1_k127_5751039_12	1236689.MMALV_01790	5.862e-73	255.0	COG0592@1|root,arCOG00488@2157|Archaea,2XT8B@28890|Euryarchaeota,3F2MA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
DYD1_k127_5751039_19	1303518.CCALI_01352	5.026e-54	204.0	COG1737@1|root,COG1737@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3150,bact-PGI_C
DYD1_k127_5751039_25	1042877.GQS_07735	8.779e-41	161.0	COG1772@1|root,arCOG04364@2157|Archaea,2XXJ6@28890|Euryarchaeota,243JJ@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF531)	-	-	-	ko:K09725	-	-	-	-	ko00000	-	-	-	DUF531
DYD1_k127_5751039_31	453591.Igni_0915	4.004e-34	141.0	COG1051@1|root,arCOG01075@2157|Archaea,2XR8E@28889|Crenarchaeota	28889|Crenarchaeota	L	PFAM NUDIX hydrolase	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
DYD1_k127_5751039_40	1236689.MMALV_01780	1.384e-17	87.0	COG1594@1|root,arCOG00579@2157|Archaea,2XXU7@28890|Euryarchaeota,3F2T6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	RNA polymerase subunit 9	tfs2	-	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	RNA_POL_M_15KD,TFIIS_C
DYD1_k127_5751039_37	529709.PYCH_03970	1.643e-28	118.0	COG1990@1|root,arCOG04228@2157|Archaea,2XYRE@28890|Euryarchaeota,24457@183968|Thermococci	183968|Thermococci	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
DYD1_k127_5751039_47	340099.Teth39_1310	9.472e-11	73.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,42GNQ@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Thiamin pyrophosphokinase catalytic	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
DYD1_k127_5751039_41	765911.Thivi_3598	2.158e-17	87.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1S8U3@1236|Gammaproteobacteria,1WYUE@135613|Chromatiales	135613|Chromatiales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
DYD1_k127_5751039_39	45157.CMC092CT	5.773e-20	100.0	COG0500@1|root,KOG1331@2759|Eukaryota	2759|Eukaryota	Q	tRNA (uracil) methyltransferase activity	-	GO:0000049,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.229	ko:K10770	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	2OG-FeII_Oxy_2,Methyltransf_11,Rad60-SLD_2
DYD1_k127_5751039_35	1380390.JIAT01000009_gene419	5.23e-30	134.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4CPUJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
DYD1_k127_5751039_24	743718.Isova_1773	1.049e-41	177.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,2GNGF@201174|Actinobacteria,4F43T@85017|Promicromonosporaceae	201174|Actinobacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF1080
DYD1_k127_5751039_44	1247963.JPHU01000014_gene1017	1.922e-15	90.0	2CGCV@1|root,31JER@2|Bacteria,1RJJ8@1224|Proteobacteria,2USHC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thrombospondin C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TSP_C
DYD1_k127_5751039_51	215803.DB30_4251	2.204e-06	61.0	COG1404@1|root,COG3055@1|root,COG3291@1|root,COG3509@1|root,COG5295@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,COG5295@2|Bacteria,1Q4PP@1224|Proteobacteria,42YRG@68525|delta/epsilon subdivisions,2WUJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
DYD1_k127_5751039_43	1210884.HG799464_gene10802	6.411e-16	85.0	COG1547@1|root,COG1547@2|Bacteria,2J0XW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
DYD1_k127_5751039_34	572546.Arcpr_0133	1.059e-31	131.0	COG1727@1|root,arCOG00780@2157|Archaea,2XZ6R@28890|Euryarchaeota,246C1@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the eukaryotic ribosomal protein eL18 family	rpl18e	-	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18,Ribosomal_L27A
DYD1_k127_5751039_32	368407.Memar_1805	4.169e-34	136.0	COG0102@1|root,arCOG04242@2157|Archaea,2XWN6@28890|Euryarchaeota,2N9Q5@224756|Methanomicrobia	224756|Methanomicrobia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DYD1_k127_5751039_20	1054217.TALC_01380	4.137e-47	173.0	COG0088@1|root,arCOG04243@2157|Archaea,2XWK0@28890|Euryarchaeota,241SC@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the universal ribosomal protein uS9 family	rps9	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DYD1_k127_5751039_42	1236689.MMALV_14760	4.82e-17	84.0	COG1644@1|root,arCOG04244@2157|Archaea,2Y03I@28890|Euryarchaeota,3F2UX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoN	GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03058	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_N
DYD1_k127_5751039_36	710686.Mycsm_01630	2.268e-29	128.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,235VP@1762|Mycobacteriaceae	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DYD1_k127_5751039_5	1042877.GQS_01555	1.742e-112	383.0	COG0714@1|root,arCOG00434@2157|Archaea,2XSZU@28890|Euryarchaeota,243N7@183968|Thermococci	183968|Thermococci	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DYD1_k127_5751039_29	693661.Arcve_1149	1.933e-38	160.0	COG1721@1|root,arCOG02742@2157|Archaea,2Y7CK@28890|Euryarchaeota,246B6@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DYD1_k127_5751039_23	330214.NIDE4014	7.406e-42	174.0	2EUIU@1|root,33N0V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5751039_14	867903.ThesuDRAFT_02120	1.241e-70	245.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes	1239|Firmicutes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DYD1_k127_5757253_15	795797.C497_16577	6.834e-13	82.0	COG0577@1|root,arCOG03256@1|root,arCOG07560@1|root,arCOG02312@2157|Archaea,arCOG03256@2157|Archaea,arCOG07560@2157|Archaea,2XTCP@28890|Euryarchaeota,23UG6@183963|Halobacteria	183963|Halobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
DYD1_k127_5757253_8	1123253.AUBD01000008_gene467	1.555e-48	183.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1X623@135614|Xanthomonadales	135614|Xanthomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_5757253_0	1123354.AUDR01000016_gene1410	7.271e-121	411.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,1KRIS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
DYD1_k127_5757253_3	335541.Swol_0731	4.498e-81	284.0	COG0472@1|root,COG0472@2|Bacteria	2|Bacteria	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	wbpL	-	2.7.8.33,2.7.8.35	ko:K02851,ko:K13007	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
DYD1_k127_5757253_9	1123392.AQWL01000001_gene1561	5.94e-48	183.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,2VJHC@28216|Betaproteobacteria,1KTE1@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DYD1_k127_5757253_13	1144319.PMI16_04723	1.99e-22	103.0	COG1216@1|root,COG1216@2|Bacteria,1RB30@1224|Proteobacteria,2VVJ1@28216|Betaproteobacteria,4787K@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD1_k127_5757253_4	1123248.KB893348_gene87	1.929e-78	271.0	COG3751@1|root,COG3751@2|Bacteria,4NJ06@976|Bacteroidetes	976|Bacteroidetes	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
DYD1_k127_5757253_16	1046724.KB889851_gene2272	0.0006382	49.0	COG3677@1|root,COG3677@2|Bacteria,1R97R@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
DYD1_k127_5757253_14	349521.HCH_01459	2.454e-18	89.0	COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1XS39@135619|Oceanospirillales	135619|Oceanospirillales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
DYD1_k127_5757253_2	767029.HMPREF9154_2962	1.5e-84	286.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DYD1_k127_5757253_1	309799.DICTH_0427	3.701e-96	327.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	wecB	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DYD1_k127_5757253_12	660470.Theba_2110	3.856e-26	114.0	COG2030@1|root,COG2030@2|Bacteria,2GD2R@200918|Thermotogae	200918|Thermotogae	I	PFAM MaoC domain protein dehydratase	-	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
DYD1_k127_5757253_7	1123371.ATXH01000018_gene1376	1.747e-49	185.0	COG1028@1|root,COG1028@2|Bacteria,2GH4K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DYD1_k127_5757253_10	1227739.Hsw_1654	1.25e-36	152.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	2.3.1.157,2.3.1.79,2.7.7.23	ko:K00661,ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
DYD1_k127_5757253_6	518766.Rmar_1322	1.623e-56	216.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1FIXH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DYD1_k127_5757253_5	649747.HMPREF0083_04835	2.702e-60	226.0	COG2244@1|root,COG2244@2|Bacteria,1UXZ7@1239|Firmicutes,4HGGI@91061|Bacilli,26UU2@186822|Paenibacillaceae	91061|Bacilli	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
DYD1_k127_5821505_17	439481.Aboo_0123	1.143e-58	214.0	COG0638@1|root,arCOG00970@2157|Archaea,2XUIZ@28890|Euryarchaeota,3F2PC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
DYD1_k127_5821505_1	1041930.Mtc_2119	1.674e-250	788.0	COG1782@1|root,arCOG00543@2157|Archaea,2XTIM@28890|Euryarchaeota,2N99U@224756|Methanomicrobia	224756|Methanomicrobia	S	KH, type 1, domain	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_2,KH_7,Lactamase_B,Lactamase_B_6,RMMBL
DYD1_k127_5821505_7	1502851.FG93_03415	4.254e-116	381.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,3JRP5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	MA20_37085	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
DYD1_k127_5821505_32	1304865.JAGF01000001_gene2131	1.846e-19	91.0	2EAYY@1|root,334ZV@2|Bacteria,2I2ZT@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
DYD1_k127_5821505_48	1996.JOFO01000044_gene4130	7.727e-05	54.0	COG1522@1|root,COG1522@2|Bacteria,2GVHQ@201174|Actinobacteria,4EJRK@85012|Streptosporangiales	201174|Actinobacteria	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
DYD1_k127_5821505_19	251221.35213266	1.591e-53	194.0	COG0625@1|root,COG0625@2|Bacteria,1G34I@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
DYD1_k127_5821505_22	1121033.AUCF01000004_gene5038	1.379e-46	175.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,2JRYS@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
DYD1_k127_5821505_25	1211112.ALJC01000105_gene2314	1.215e-31	140.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
DYD1_k127_5821505_13	673860.AciM339_1471	9.225e-71	252.0	COG0037@1|root,arCOG00042@2157|Archaea,2XTEZ@28890|Euryarchaeota,3F2HB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	PP-loop family	tuc1	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
DYD1_k127_5821505_5	272844.PAB1901	1.233e-119	404.0	COG0252@1|root,arCOG01924@2157|Archaea,2XTN1@28890|Euryarchaeota,2439K@183968|Thermococci	183968|Thermococci	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
DYD1_k127_5821505_3	1236689.MMALV_16300	8.13e-164	537.0	COG2511@1|root,arCOG01719@2157|Archaea,2XT73@28890|Euryarchaeota,3F2IW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
DYD1_k127_5821505_39	944480.ATUV01000002_gene412	2.3e-12	71.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	chpA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
DYD1_k127_5821505_28	593750.Metfor_2739	9.728e-25	111.0	COG3465@1|root,arCOG03889@2157|Archaea,2Y55D@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5821505_37	593750.Metfor_2738	3.214e-15	79.0	arCOG00733@1|root,arCOG00733@2157|Archaea	2157|Archaea	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
DYD1_k127_5821505_26	1128421.JAGA01000001_gene2396	2.49e-26	122.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DYD1_k127_5821505_23	745411.B3C1_07691	1.238e-39	153.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,1T0GF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1
DYD1_k127_5821505_33	1162668.LFE_1240	2.349e-18	93.0	COG1765@1|root,COG1765@2|Bacteria	1162668.LFE_1240|-	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5821505_44	797209.ZOD2009_13616	1.313e-08	68.0	COG3398@1|root,arCOG02611@2157|Archaea,2XV4M@28890|Euryarchaeota,23V38@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD1_k127_5821505_36	1254432.SCE1572_18790	1.567e-15	84.0	2EP0F@1|root,33GMA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5821505_49	1070774.J07HN4v3_01347	0.0002422	53.0	COG1522@1|root,arCOG01582@2157|Archaea,2XWK2@28890|Euryarchaeota,23V6A@183963|Halobacteria	183963|Halobacteria	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_5821505_51	926554.KI912671_gene317	0.0006324	48.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	3.1.1.45	ko:K01061,ko:K15945	ko00361,ko00364,ko00623,ko01057,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01057,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222,R09330	RC00046,RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	SnoaL,SnoaL_2
DYD1_k127_5821505_41	1385510.N781_16860	1.074e-09	62.0	COG0454@1|root,COG0456@2|Bacteria,1VH1H@1239|Firmicutes,4HZ4Y@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
DYD1_k127_5821505_34	1385510.N781_16860	1.153e-16	81.0	COG0454@1|root,COG0456@2|Bacteria,1VH1H@1239|Firmicutes,4HZ4Y@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
DYD1_k127_5821505_16	243265.plu3102	2.047e-61	223.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,1T3H0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DYD1_k127_5821505_35	595460.RRSWK_07188	1.753e-16	94.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	HEAT_2,Peptidase_M9,Peptidase_M9_N
DYD1_k127_5821505_47	645465.ACUR01000569_gene5972	1.8e-05	56.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
DYD1_k127_5821505_4	1121939.L861_17285	2.829e-133	441.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
DYD1_k127_5821505_30	1206731.BAGB01000045_gene5050	5.082e-20	105.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4FVSE@85025|Nocardiaceae	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DYD1_k127_5821505_43	504728.K649_03545	2.52e-09	61.0	COG2026@1|root,COG2026@2|Bacteria,1WN9J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
DYD1_k127_5821505_50	521011.Mpal_1787	0.0003338	46.0	arCOG03966@1|root,arCOG03966@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_5821505_20	926560.KE387023_gene3024	2.631e-52	199.0	COG0604@1|root,COG0604@2|Bacteria,1WM8H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
DYD1_k127_5821505_6	118168.MC7420_5523	7.787e-117	380.0	COG0189@1|root,COG0189@2|Bacteria,1G0DT@1117|Cyanobacteria,1H6ZT@1150|Oscillatoriales	1117|Cyanobacteria	F	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,Zn_protease
DYD1_k127_5821505_42	1191299.AJYX01000055_gene2254	1.565e-09	67.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1XT40@135623|Vibrionales	135623|Vibrionales	F	Belongs to the RimK family	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
DYD1_k127_5821505_24	288705.RSal33209_2893	1.771e-33	148.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,1W8KD@1268|Micrococcaceae	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
DYD1_k127_5821505_46	1206744.BAGL01000087_gene2741	2.338e-07	61.0	COG1716@1|root,COG3629@1|root,COG1716@2|Bacteria,COG3629@2|Bacteria,2HEQI@201174|Actinobacteria,4FVV3@85025|Nocardiaceae	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,FHA,Trans_reg_C,Yop-YscD_cpl
DYD1_k127_5821505_9	1054217.TALC_00241	8.637e-110	372.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,241IG@183967|Thermoplasmata	183967|Thermoplasmata	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DYD1_k127_5821505_18	266117.Rxyl_1624	2.05e-55	207.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPFB@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DYD1_k127_5821505_21	795797.C497_04872	3.968e-49	190.0	COG0628@1|root,arCOG02642@2157|Archaea,2XT00@28890|Euryarchaeota,23TDZ@183963|Halobacteria	183963|Halobacteria	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DYD1_k127_5821505_12	192952.MM_0785	1.696e-72	270.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,2N9EB@224756|Methanomicrobia	224756|Methanomicrobia	C	Belongs to the V-ATPase 116 kDa subunit family	atpI-1	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
DYD1_k127_5821505_31	387631.Asulf_02197	1.625e-19	94.0	COG0636@1|root,arCOG02455@2157|Archaea,2XZRP@28890|Euryarchaeota,246DQ@183980|Archaeoglobi	183980|Archaeoglobi	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
DYD1_k127_5821505_29	410358.Mlab_1219	4.989e-22	103.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,2N9TB@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
DYD1_k127_5821505_14	1041930.Mtc_1398	9.92e-71	252.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,2N9HH@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0388	vATP-synt_AC39
DYD1_k127_5821505_27	521011.Mpal_2678	7.049e-25	106.0	COG1436@1|root,arCOG04102@2157|Archaea,2XXYI@28890|Euryarchaeota,2N9YY@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
DYD1_k127_5821505_0	1094980.Mpsy_2506	6.372e-266	829.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,2N93M@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
DYD1_k127_5821505_2	1094980.Mpsy_2507	1.149e-230	722.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2N97D@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
DYD1_k127_5821505_15	521011.Mpal_2675	9.023e-69	240.0	COG1394@1|root,arCOG04101@2157|Archaea,2XTQ5@28890|Euryarchaeota,2N9IG@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0384	ATP-synt_D
DYD1_k127_5821505_8	994479.GL877880_gene3721	6.926e-116	386.0	COG0498@1|root,COG0498@2|Bacteria,2GNZD@201174|Actinobacteria,4DZGT@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD1_k127_5821505_45	1380390.JIAT01000010_gene3558	8.288e-08	64.0	COG0625@1|root,COG0625@2|Bacteria,2HQC6@201174|Actinobacteria,4CRWK@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
DYD1_k127_5821505_40	1296415.JACC01000002_gene3276	1.019e-09	67.0	COG1733@1|root,COG1733@2|Bacteria,4NT53@976|Bacteroidetes,1IJ4A@117743|Flavobacteriia,2YM5J@290174|Aquimarina	976|Bacteroidetes	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_5821505_10	1041930.Mtc_0200	1.092e-87	310.0	COG0367@1|root,COG0449@1|root,arCOG00057@2157|Archaea,arCOG00071@2157|Archaea,2XV5E@28890|Euryarchaeota,2N9BC@224756|Methanomicrobia	224756|Methanomicrobia	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB-1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DYD1_k127_5821505_11	1123261.AXDW01000018_gene782	5.936e-82	289.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,1RYCF@1236|Gammaproteobacteria,1X5DG@135614|Xanthomonadales	135614|Xanthomonadales	U	Glutamate-cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GshA
DYD1_k127_5821505_38	273677.BW34_01461	2.336e-13	85.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DYD1_k127_5944077_1	1121405.dsmv_0512	2.764e-70	256.0	COG0475@1|root,COG0475@2|Bacteria,1PK6V@1224|Proteobacteria,439WW@68525|delta/epsilon subdivisions,2X290@28221|Deltaproteobacteria,2MPC7@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DYD1_k127_5944077_7	1121448.DGI_2569	2.197e-17	96.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria,2M895@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
DYD1_k127_5944077_5	604354.TSIB_0244	4.754e-38	154.0	COG1756@1|root,arCOG04122@2157|Archaea,2XX9G@28890|Euryarchaeota,243H9@183968|Thermococci	183968|Thermococci	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
DYD1_k127_5944077_0	269797.Mbar_A1334	2.71e-148	477.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota,2N9G6@224756|Methanomicrobia	224756|Methanomicrobia	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
DYD1_k127_5944077_3	521098.Aaci_2056	2.182e-59	222.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,277VZ@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	yngJ	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_5944077_2	593117.TGAM_0269	5.755e-60	231.0	COG2262@1|root,arCOG00353@2157|Archaea,2XT2W@28890|Euryarchaeota,2431W@183968|Thermococci	183968|Thermococci	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DYD1_k127_5944077_6	1220534.B655_0233	1.388e-27	124.0	COG0561@1|root,arCOG01213@2157|Archaea,2XX94@28890|Euryarchaeota,23PJ1@183925|Methanobacteria	183925|Methanobacteria	G	Catalyzes the dephosphorylation of 2-phosphoglycolate	gph	-	3.1.3.18	ko:K22223	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3,S6PP
DYD1_k127_5944077_4	1041930.Mtc_2247	1.187e-51	195.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,2N98Y@224756|Methanomicrobia	224756|Methanomicrobia	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
DYD1_k127_6041120_0	751944.HALDL1_12635	1.253e-95	329.0	COG0733@1|root,arCOG04466@2157|Archaea,2XUDC@28890|Euryarchaeota,23T6P@183963|Halobacteria	183963|Halobacteria	S	COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
DYD1_k127_6041120_1	323259.Mhun_0933	1.868e-07	61.0	COG2426@1|root,arCOG01330@2157|Archaea,2Y4KG@28890|Euryarchaeota	28890|Euryarchaeota	S	Small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
DYD1_k127_6099525_0	1094980.Mpsy_2351	5.712e-78	273.0	COG1955@1|root,arCOG01809@2157|Archaea,2XTAX@28890|Euryarchaeota,2N9WG@224756|Methanomicrobia	224756|Methanomicrobia	N	type II secretion system protein	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DYD1_k127_6106823_32	1304284.L21TH_1983	2.78e-06	58.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TniQ
DYD1_k127_6106823_27	673860.AciM339_1195	1.405e-14	77.0	COG1761@1|root,arCOG04111@2157|Archaea,2XZVZ@28890|Euryarchaeota,3F2UR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoL	-	2.7.7.6	ko:K03056	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_L_2
DYD1_k127_6106823_5	1094980.Mpsy_2606	6.566e-95	329.0	COG0585@1|root,arCOG04252@2157|Archaea,2XUTK@28890|Euryarchaeota,2N928@224756|Methanomicrobia	224756|Methanomicrobia	J	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
DYD1_k127_6106823_15	1408418.JNJH01000004_gene1953	2.153e-34	134.0	COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,2UEJ2@28211|Alphaproteobacteria,2JY7U@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
DYD1_k127_6106823_31	573.JG24_05535	8.716e-07	61.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,1RR7A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_6106823_2	304371.MCP_1830	2.037e-137	443.0	COG0470@1|root,arCOG00469@2157|Archaea,2XTC8@28890|Euryarchaeota,2N91S@224756|Methanomicrobia	224756|Methanomicrobia	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcS	-	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,DNA_pol3_delta2,Rad17,Rep_fac_C
DYD1_k127_6106823_10	589924.Ferp_1976	1.69e-46	189.0	COG2518@1|root,arCOG00976@2157|Archaea,2XTRM@28890|Euryarchaeota,245QI@183980|Archaeoglobi	183980|Archaeoglobi	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DYD1_k127_6106823_24	471852.Tcur_3067	7.368e-18	94.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria,4EK3E@85012|Streptosporangiales	201174|Actinobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DYD1_k127_6106823_14	593750.Metfor_2693	7.659e-35	154.0	COG1502@1|root,arCOG02039@2157|Archaea,2XTH3@28890|Euryarchaeota	28890|Euryarchaeota	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	pld	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
DYD1_k127_6106823_16	1237149.C900_01167	1.066e-32	139.0	COG1913@1|root,COG1913@2|Bacteria,4NJFJ@976|Bacteroidetes,47Q85@768503|Cytophagia	976|Bacteroidetes	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
DYD1_k127_6106823_17	1054217.TALC_01499	4.945e-32	136.0	COG1916@1|root,arCOG02142@2157|Archaea	2157|Archaea	S	homolog of PrgY (pheromone shutdown protein)	traB	-	-	-	-	-	-	-	-	-	-	-	TraB
DYD1_k127_6106823_7	246197.MXAN_5983	8.097e-70	244.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,43BAG@68525|delta/epsilon subdivisions,2X6PP@28221|Deltaproteobacteria,2YUZG@29|Myxococcales	28221|Deltaproteobacteria	H	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
DYD1_k127_6106823_30	700598.Niako_3813	2.041e-07	63.0	COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1J0ID@117747|Sphingobacteriia	976|Bacteroidetes	H	TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region	-	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD1_k127_6106823_34	1519464.HY22_10160	3.176e-06	59.0	COG4773@1|root,COG4773@2|Bacteria	2|Bacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DYD1_k127_6106823_37	1089550.ATTH01000001_gene426	4.198e-05	55.0	COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1FISC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DYD1_k127_6106823_39	1233950.IW22_05165	0.0005554	51.0	COG1629@1|root,COG4771@2|Bacteria,4NFAM@976|Bacteroidetes,1I0N0@117743|Flavobacteriia,3ZPSV@59732|Chryseobacterium	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD1_k127_6106823_38	1392490.JHZX01000001_gene3503	0.0001816	53.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXSI@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD1_k127_6106823_33	1313301.AUGC01000011_gene1114	2.815e-06	59.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes	976|Bacteroidetes	P	Tonb-dependent siderophore receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD1_k127_6106823_28	797114.C475_20702	8.516e-12	78.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWHT@28890|Euryarchaeota,23V64@183963|Halobacteria	183963|Halobacteria	K	protein conserved in archaea	gntR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_5,MarR_2
DYD1_k127_6106823_0	269797.Mbar_A1209	5.709e-183	590.0	COG0423@1|root,arCOG00405@2157|Archaea,2XSZK@28890|Euryarchaeota,2N999@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM tRNA synthetase, class II (G, H, P and S)	glyS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
DYD1_k127_6106823_18	1054217.TALC_01073	4.866e-30	133.0	COG0402@1|root,arCOG00692@2157|Archaea,2XSYB@28890|Euryarchaeota,242BM@183967|Thermoplasmata	183967|Thermoplasmata	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DYD1_k127_6106823_29	81824.XP_001743708.1	1.609e-07	66.0	2ECT2@1|root,2SIJX@2759|Eukaryota,3A4NN@33154|Opisthokonta	33154|Opisthokonta	S	Carbohydrate esterase family 3 protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,VCBS
DYD1_k127_6106823_8	391623.TERMP_00711	1.347e-65	236.0	COG0270@1|root,arCOG04157@2157|Archaea,2XV2K@28890|Euryarchaeota,24378@183968|Thermococci	183968|Thermococci	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
DYD1_k127_6106823_1	439481.Aboo_0966	4.279e-175	563.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,3F2GK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	tRNA-splicing ligase RtcB	rtcB	GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
DYD1_k127_6106823_13	768706.Desor_3735	1.815e-36	150.0	COG0642@1|root,COG0745@1|root,COG1145@1|root,COG2199@1|root,COG4624@1|root,COG0745@2|Bacteria,COG1145@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG4624@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,264H3@186807|Peptococcaceae	186801|Clostridia	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,HATPase_c,HisKA,Response_reg
DYD1_k127_6106823_23	1382306.JNIM01000001_gene1806	4.44e-19	93.0	COG1371@1|root,COG1371@2|Bacteria,2G7BQ@200795|Chloroflexi	200795|Chloroflexi	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
DYD1_k127_6106823_20	1123279.ATUS01000001_gene2572	5.197e-23	113.0	2C75R@1|root,2ZCK5@2|Bacteria,1NMP7@1224|Proteobacteria,1SHMJ@1236|Gammaproteobacteria,1J86N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
DYD1_k127_6106823_11	203119.Cthe_0254	3.407e-46	184.0	COG1721@1|root,COG1721@2|Bacteria,1VQXY@1239|Firmicutes,24XUK@186801|Clostridia,3WNB5@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DYD1_k127_6106823_3	1042877.GQS_01555	1.907e-117	387.0	COG0714@1|root,arCOG00434@2157|Archaea,2XSZU@28890|Euryarchaeota,243N7@183968|Thermococci	183968|Thermococci	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DYD1_k127_6106823_4	292459.STH2009	5.026e-116	386.0	COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,248E0@186801|Clostridia	186801|Clostridia	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DYD1_k127_6106823_25	694430.Natoc_0714	8.424e-17	86.0	COG1308@1|root,arCOG04061@2157|Archaea,2XXYV@28890|Euryarchaeota,23W5Q@183963|Halobacteria	183963|Halobacteria	K	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC,UBA_4
DYD1_k127_6106823_6	1236689.MMALV_03080	4.092e-79	283.0	COG0063@1|root,arCOG00018@2157|Archaea,2XU4W@28890|Euryarchaeota,3F2MH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DYD1_k127_6106823_36	653733.Selin_2106	1.8e-05	56.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_M6
DYD1_k127_6106823_26	595460.RRSWK_07188	5.613e-15	89.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	HEAT_2,Peptidase_M9,Peptidase_M9_N
DYD1_k127_6106823_22	1286093.C266_19660	1.201e-20	98.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2VU05@28216|Betaproteobacteria,1KFHA@119060|Burkholderiaceae	28216|Betaproteobacteria	P	arsenate reductase	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
DYD1_k127_6106823_12	351160.RCIX578	5.997e-37	148.0	COG2042@1|root,arCOG04733@2157|Archaea,2XVBD@28890|Euryarchaeota,2N9PH@224756|Methanomicrobia	224756|Methanomicrobia	J	pre-rRNA processing protein involved in ribosome biogenesis	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
DYD1_k127_6106823_9	1236689.MMALV_01840	4.966e-51	195.0	COG2520@1|root,arCOG10124@2157|Archaea,2XTPV@28890|Euryarchaeota,3F2KV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Met-10+ like-protein	taw2	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.5.1.114	ko:K07055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Met_10
DYD1_k127_6106823_21	1713.JOFV01000018_gene245	1.363e-22	105.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria,4F2IC@85016|Cellulomonadaceae	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DYD1_k127_6106823_19	1457250.BBMO01000001_gene739	9.753e-27	119.0	COG0613@1|root,arCOG00302@2157|Archaea,2XSWE@28890|Euryarchaeota,23TEN@183963|Halobacteria	183963|Halobacteria	S	metal-dependent phosphoesterases (PHP family)	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
DYD1_k127_6248246_14	565033.GACE_0614	9.641e-05	49.0	COG3364@1|root,arCOG04417@2157|Archaea,2XU3V@28890|Euryarchaeota,246DN@183980|Archaeoglobi	183980|Archaeoglobi	S	Zn-ribbon containing protein	-	-	-	ko:K07163	-	-	-	-	ko00000	-	-	-	DUF2072
DYD1_k127_6248246_7	673860.AciM339_0073	5.731e-39	158.0	COG3273@1|root,arCOG01963@2157|Archaea,2XSXK@28890|Euryarchaeota,3F2NX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	PhoU domain	pchB	-	-	-	-	-	-	-	-	-	-	-	PhoU,TrkA_C
DYD1_k127_6248246_8	272569.rrnAC2512	1.163e-38	160.0	COG3273@1|root,arCOG01963@2157|Archaea,2XSXK@28890|Euryarchaeota,23RY7@183963|Halobacteria	183963|Halobacteria	P	TrkA-C domain-containing protein	pchB	-	-	-	-	-	-	-	-	-	-	-	PhoU,TrkA_C
DYD1_k127_6248246_11	523841.HFX_0134	2.186e-12	75.0	COG1824@1|root,arCOG00624@2157|Archaea,2XUJE@28890|Euryarchaeota,23TQJ@183963|Halobacteria	183963|Halobacteria	P	to cation transporters	mgtE2	-	-	ko:K07244	-	-	-	-	ko00000,ko02000	1.A.26.3	-	-	MgtE
DYD1_k127_6248246_9	1094980.Mpsy_0042	4.624e-26	114.0	COG1824@1|root,arCOG00624@2157|Archaea,2XUJE@28890|Euryarchaeota,2NA1G@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM MgtE integral membrane region	-	-	-	ko:K07244	-	-	-	-	ko00000,ko02000	1.A.26.3	-	iAF692.Mbar_A2809	MgtE
DYD1_k127_6248246_13	349741.Amuc_1291	2.979e-06	61.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
DYD1_k127_6248246_6	93220.LV28_09055	2.921e-42	163.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,2VTDF@28216|Betaproteobacteria,1K4TZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
DYD1_k127_6248246_3	292459.STH2403	4.396e-94	320.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes	1239|Firmicutes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DYD1_k127_6248246_10	477641.MODMU_3489	2.322e-14	84.0	COG0524@1|root,COG0524@2|Bacteria,2GKBG@201174|Actinobacteria,4ERNY@85013|Frankiales	201174|Actinobacteria	G	PFAM PfkB domain protein	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
DYD1_k127_6248246_12	222984.JNCS01000001_gene1937	2.328e-06	60.0	COG4885@1|root,COG5276@1|root,arCOG02565@2157|Archaea,arCOG04478@2157|Archaea,2XV6J@28890|Euryarchaeota,23SNQ@183963|Halobacteria	183963|Halobacteria	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_6248246_1	330214.NIDE0014	1.18e-143	467.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DYD1_k127_6248246_0	1054217.TALC_00076	2.953e-155	502.0	COG0499@1|root,arCOG04137@2157|Archaea,2XT4S@28890|Euryarchaeota,241J8@183967|Thermoplasmata	183967|Thermoplasmata	F	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DYD1_k127_6248246_4	2325.TKV_c00230	4.577e-65	229.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
DYD1_k127_6248246_2	115417.EPrPW00000020869	3.103e-118	399.0	COG0626@1|root,KOG0053@2759|Eukaryota,1MBH3@121069|Pythiales	121069|Pythiales	E	Cystathionine gamma-lyase. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
DYD1_k127_6248246_5	1121104.AQXH01000002_gene637	1.359e-53	193.0	COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,1IQU6@117747|Sphingobacteriia	976|Bacteroidetes	E	Cystathionine beta-synthase	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
DYD1_k127_6293609_0	1041930.Mtc_1221	5.463e-08	62.0	COG1051@1|root,arCOG01075@2157|Archaea,2Y1UG@28890|Euryarchaeota	28890|Euryarchaeota	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
DYD1_k127_6337085_0	1089547.KB913013_gene190	5.343e-13	76.0	COG3926@1|root,COG3926@2|Bacteria,4NRDK@976|Bacteroidetes,47QX6@768503|Cytophagia	976|Bacteroidetes	S	Predicted Peptidoglycan domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
DYD1_k127_637097_0	941824.TCEL_00325	0.0	1152.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,36E0I@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DYD1_k127_637097_4	926692.AZYG01000019_gene239	3.113e-138	463.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WAG5@53433|Halanaerobiales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
DYD1_k127_637097_7	224325.AF_1424	9.57e-117	396.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,245T6@183980|Archaeoglobi	183980|Archaeoglobi	J	phenylalanyl-tRNA synthetase, beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5
DYD1_k127_637097_6	693661.Arcve_1203	4.237e-118	392.0	COG1257@1|root,arCOG04260@2157|Archaea,2XTV9@28890|Euryarchaeota,245ZK@183980|Archaeoglobi	183980|Archaeoglobi	I	Hydroxymethylglutaryl-CoA reductase, degradative	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
DYD1_k127_637097_24	469382.Hbor_17820	3.019e-21	96.0	COG1781@1|root,arCOG04229@2157|Archaea,2XWP4@28890|Euryarchaeota,23VBF@183963|Halobacteria	183963|Halobacteria	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
DYD1_k127_637097_9	1054217.TALC_01157	4.183e-85	292.0	COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,241J0@183967|Thermoplasmata	183967|Thermoplasmata	F	aspartate carbamoyltransferase activity	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DYD1_k127_637097_26	1089549.AZUQ01000001_gene320	4.479e-09	67.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4EZID@85014|Glycomycetales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DYD1_k127_637097_19	1226994.AMZB01000094_gene689	4.29e-37	162.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1YIGT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_637097_20	1379698.RBG1_1C00001G0584	4.232e-36	158.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.24.40	ko:K01406,ko:K14274,ko:K20276,ko:K21449	ko00040,ko01503,ko02024,map00040,map01503,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL
DYD1_k127_637097_8	391623.TERMP_01881	2.283e-97	334.0	COG0402@1|root,arCOG00695@2157|Archaea,2XTJS@28890|Euryarchaeota,242MF@183968|Thermococci	183968|Thermococci	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
DYD1_k127_637097_1	1304880.JAGB01000002_gene2135	2.864e-271	870.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DYD1_k127_637097_15	1232437.KL661976_gene4967	8.833e-44	163.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,2MJV4@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DYD1_k127_637097_11	290397.Adeh_1245	4.145e-83	293.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
DYD1_k127_637097_3	1442599.JAAN01000043_gene411	5.566e-170	548.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1X44Q@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
DYD1_k127_637097_14	593117.TGAM_0925	1.291e-49	194.0	COG2520@1|root,arCOG00033@2157|Archaea,2XTSI@28890|Euryarchaeota,242WN@183968|Thermococci	183968|Thermococci	J	Met-10+ like-protein	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
DYD1_k127_637097_13	797302.Halru_1978	4.893e-59	214.0	COG1798@1|root,arCOG04161@2157|Archaea,2XV63@28890|Euryarchaeota,23TI8@183963|Halobacteria	183963|Halobacteria	H	S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis	dphB	-	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	-	TP_methylase
DYD1_k127_637097_23	579137.Metvu_0421	3.003e-22	107.0	COG3398@1|root,arCOG02611@2157|Archaea,2XW64@28890|Euryarchaeota,23PZT@183939|Methanococci	183939|Methanococci	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_637097_18	439235.Dalk_2209	1.602e-37	162.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42NUP@68525|delta/epsilon subdivisions,2WKSD@28221|Deltaproteobacteria,2MNKG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-1	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
DYD1_k127_637097_10	1094980.Mpsy_1195	6.479e-85	295.0	COG1899@1|root,arCOG04142@2157|Archaea,2XUTF@28890|Euryarchaeota,2N9AF@224756|Methanomicrobia	224756|Methanomicrobia	O	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys-1	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DYD1_k127_637097_5	1343739.PAP_06745	1.385e-128	424.0	COG0012@1|root,arCOG00357@2157|Archaea,2XTZG@28890|Euryarchaeota,243A3@183968|Thermococci	183968|Thermococci	J	GTPase of unknown function C-terminal	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
DYD1_k127_637097_12	1094980.Mpsy_2322	8.521e-63	227.0	COG4801@1|root,arCOG02471@2157|Archaea,2XSX3@28890|Euryarchaeota,2N9N8@224756|Methanomicrobia	224756|Methanomicrobia	S	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,Hexapep
DYD1_k127_637097_27	1396141.BATP01000040_gene2087	5.985e-09	70.0	COG2273@1|root,COG3209@1|root,COG4625@1|root,COG2273@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF5011,He_PIG,Laminin_G_3,PATR,Phospholip_A2_3,RHS_repeat
DYD1_k127_637097_28	408672.NBCG_04609	1.862e-06	61.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2I66N@201174|Actinobacteria,4DQ53@85009|Propionibacteriales	201174|Actinobacteria	O	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cleaved_Adhesin,Kelch_1,Peptidase_S8
DYD1_k127_637097_30	69014.TK1372	0.0009642	46.0	arCOG00818@1|root,arCOG00818@2157|Archaea	2157|Archaea	S	AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
DYD1_k127_637097_2	439481.Aboo_1381	6.898e-207	689.0	COG1196@1|root,arCOG00371@2157|Archaea,2XSVK@28890|Euryarchaeota,3F2HY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DYD1_k127_637097_16	673860.AciM339_1194	1.034e-40	166.0	COG1354@1|root,arCOG02610@2157|Archaea,2XZHK@28890|Euryarchaeota,3F2QG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
DYD1_k127_637097_22	192952.MM_1029	7.29e-27	121.0	COG1386@1|root,arCOG02613@2157|Archaea,2XZ7Q@28890|Euryarchaeota,2N9UX@224756|Methanomicrobia	224756|Methanomicrobia	K	Segregation and condensation complex subunit ScpB	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
DYD1_k127_637097_17	880073.Calab_0526	9.218e-39	168.0	COG1404@1|root,COG3291@1|root,COG3386@1|root,COG5276@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17,3.2.1.4	ko:K01053,ko:K01179,ko:K07214,ko:K12287	ko00030,ko00053,ko00500,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00500,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751,R06200,R11307,R11308	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko02044,ko04147	-	GH5,GH9	-	Big_5,DUF285,Esterase,He_PIG,SGL
DYD1_k127_637097_21	1379698.RBG1_1C00001G0584	2.394e-30	142.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.4.24.40	ko:K01406,ko:K14274,ko:K20276,ko:K21449	ko00040,ko01503,ko02024,map00040,map01503,map02024	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL
DYD1_k127_637097_25	1396141.BATP01000036_gene3843	5.168e-19	104.0	COG2133@1|root,COG2982@1|root,COG3291@1|root,COG4733@1|root,COG2133@2|Bacteria,COG2982@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	asmA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475	-	ko:K07289,ko:K07290,ko:K07451,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko02048	9.B.121	-	-	AsmA,AsmA_2,Phage-tail_3
DYD1_k127_643920_5	292459.STH719	1.789e-76	271.0	COG2718@1|root,COG2718@2|Bacteria,1TQIN@1239|Firmicutes,24A3U@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
DYD1_k127_643920_3	292459.STH724	2.984e-81	294.0	COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,248CW@186801|Clostridia	186801|Clostridia	S	PFAM SpoVR	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
DYD1_k127_643920_1	1157640.AQWO01000004_gene4778	9.687e-114	383.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
DYD1_k127_643920_4	323848.Nmul_A1925	1.546e-78	273.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2VJHK@28216|Betaproteobacteria,373E1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
DYD1_k127_643920_7	266117.Rxyl_0686	5.53e-45	175.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria,4CTID@84995|Rubrobacteria	84995|Rubrobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtC	-	-	-	-	-	-	-	-	-	-	-	GATase_4
DYD1_k127_643920_12	1110697.NCAST_32_03820	0.0004692	52.0	2C75R@1|root,2ZCK5@2|Bacteria,2IBVD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_643920_0	479434.Sthe_2363	1.573e-270	867.0	COG0209@1|root,COG0209@2|Bacteria,2G8RN@200795|Chloroflexi,27Y2V@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
DYD1_k127_643920_8	673860.AciM339_0770	8.129e-40	160.0	COG1047@1|root,arCOG00980@2157|Archaea,2XTB7@28890|Euryarchaeota,3F2P4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
DYD1_k127_643920_9	391625.PPSIR1_16640	2.473e-34	141.0	COG3714@1|root,COG3714@2|Bacteria,1PCNW@1224|Proteobacteria,435D5@68525|delta/epsilon subdivisions,2WZQQ@28221|Deltaproteobacteria,2Z2IZ@29|Myxococcales	28221|Deltaproteobacteria	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
DYD1_k127_643920_11	523791.Kkor_1008	1.117e-10	75.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1S07F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DYD1_k127_643920_6	296587.XP_002499809.1	5.113e-59	228.0	2E3BA@1|root,2SAF2@2759|Eukaryota,3822D@33090|Viridiplantae,34NGR@3041|Chlorophyta	2759|Eukaryota	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
DYD1_k127_643920_10	673860.AciM339_0251	7.387e-20	94.0	COG1695@1|root,arCOG00001@2157|Archaea,2Y76Y@28890|Euryarchaeota,3F3HM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
DYD1_k127_643920_2	1254432.SCE1572_45980	8.66e-110	366.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YY6R@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DYD1_k127_6481676_0	693986.MOC_3358	3.797e-05	55.0	COG1216@1|root,COG1216@2|Bacteria,1PNCS@1224|Proteobacteria,2V0YW@28211|Alphaproteobacteria,1JWHH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD1_k127_6567106_8	743718.Isova_1047	2.966e-26	111.0	28JDP@1|root,2Z97Z@2|Bacteria,2I9EC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_6567106_12	1121936.AUHI01000004_gene1684	2.657e-20	95.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli	91061|Bacilli	I	acyl-CoA dehydrogenase	yngJ	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_6567106_9	1120959.ATXF01000007_gene2309	2.31e-24	109.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria,4FQ1S@85023|Microbacteriaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
DYD1_k127_6567106_13	243231.GSU1945	0.0001619	53.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,1Q4PP@1224|Proteobacteria,42YRG@68525|delta/epsilon subdivisions,2WUJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
DYD1_k127_6567106_2	1242864.D187_008374	8.996e-70	248.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
DYD1_k127_6567106_4	673860.AciM339_0111	9.54e-52	196.0	COG1986@1|root,arCOG01221@2157|Archaea,arCOG01223@2157|Archaea,2XWGY@28890|Euryarchaeota,3F2ZA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	coaD	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K02201	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DYD1_k127_6567106_7	342949.PNA2_1780	1.151e-35	144.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,24401@183968|Thermococci	183968|Thermococci	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
DYD1_k127_6567106_0	1054217.TALC_01510	1.212e-120	402.0	COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,241JT@183967|Thermoplasmata	183967|Thermoplasmata	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DYD1_k127_6567106_1	1054217.TALC_00158	1.919e-72	252.0	COG1100@1|root,arCOG01225@2157|Archaea,2XWN4@28890|Euryarchaeota,241NA@183967|Thermoplasmata	183967|Thermoplasmata	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
DYD1_k127_6567106_5	439481.Aboo_1281	1.767e-44	172.0	COG1094@1|root,arCOG04150@2157|Archaea,2XUHX@28890|Euryarchaeota,3F2NS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	K homology RNA-binding domain	dim2	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
DYD1_k127_6567106_10	795797.C497_11548	7.795e-24	112.0	COG0723@1|root,arCOG04595@2157|Archaea,2XU6P@28890|Euryarchaeota,23SAN@183963|Halobacteria	183963|Halobacteria	C	COG0723 Rieske Fe-S protein	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
DYD1_k127_6567106_3	1041930.Mtc_1754	3.889e-54	205.0	COG1718@1|root,arCOG01180@2157|Archaea,2XU2H@28890|Euryarchaeota,2N9ET@224756|Methanomicrobia	224756|Methanomicrobia	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
DYD1_k127_6567106_6	673860.AciM339_0076	3.198e-42	174.0	COG1571@1|root,arCOG01115@2157|Archaea,2XTGD@28890|Euryarchaeota,3F2IS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743,tRNA_anti-codon
DYD1_k127_6567106_11	756883.Halar_1290	7.119e-21	98.0	COG1733@1|root,arCOG02600@2157|Archaea	2157|Archaea	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_6621452_0	983920.Y88_0877	1.814e-134	435.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,2K2UC@204457|Sphingomonadales	204457|Sphingomonadales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
DYD1_k127_6666926_10	1142394.PSMK_04790	1.589e-51	187.0	COG1573@1|root,COG1573@2|Bacteria,2J27P@203682|Planctomycetes	203682|Planctomycetes	L	uracil-dna glycosylase	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
DYD1_k127_6666926_22	673860.AciM339_1337	2.66e-11	75.0	COG3428@1|root,arCOG01917@1|root,arCOG01917@2157|Archaea,arCOG04619@2157|Archaea,2XWHU@28890|Euryarchaeota	28890|Euryarchaeota	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
DYD1_k127_6666926_9	673860.AciM339_0364	1.432e-55	205.0	COG0388@1|root,arCOG00062@2157|Archaea,2XT6R@28890|Euryarchaeota,3F2PP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Carbon-nitrogen hydrolase	-	-	3.5.1.100	ko:K18540	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
DYD1_k127_6666926_26	1293047.CBMA010000026_gene1675	2.226e-05	57.0	COG1378@1|root,arCOG02037@2157|Archaea,2XW87@28890|Euryarchaeota,23TZW@183963|Halobacteria	183963|Halobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DYD1_k127_6666926_13	420247.Msm_0142	3.624e-44	174.0	COG2102@1|root,arCOG00035@2157|Archaea,2XTNJ@28890|Euryarchaeota,23NZ0@183925|Methanobacteria	183925|Methanobacteria	S	metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter	-	-	6.3.1.14	ko:K06927	-	-	R03613	RC00358	ko00000,ko01000,ko03012	-	-	-	Diphthami_syn_2
DYD1_k127_6666926_17	1094980.Mpsy_0965	1.013e-22	113.0	COG1967@1|root,arCOG02177@2157|Archaea,2XT8V@28890|Euryarchaeota,2N9NX@224756|Methanomicrobia	224756|Methanomicrobia	S	Membrane protein of unknown function DUF63	-	-	-	-	-	-	-	-	-	-	-	-	DUF63
DYD1_k127_6666926_5	192952.MM_0590	3.48e-110	367.0	COG0371@1|root,arCOG00982@2157|Archaea,2XT0F@28890|Euryarchaeota,2N90F@224756|Methanomicrobia	224756|Methanomicrobia	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
DYD1_k127_6666926_20	386456.JQKN01000001_gene2303	2.873e-13	79.0	COG1378@1|root,arCOG02037@2157|Archaea,2XYIM@28890|Euryarchaeota	28890|Euryarchaeota	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DYD1_k127_6666926_3	1313172.YM304_32120	9.457e-123	419.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CNFR@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DYD1_k127_6666926_6	1957.JODX01000007_gene2278	2.204e-92	319.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DYD1_k127_6666926_19	439481.Aboo_0364	4.535e-14	83.0	COG1522@1|root,arCOG01586@2157|Archaea,2Y6Z8@28890|Euryarchaeota,3F2Z8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
DYD1_k127_6666926_16	391735.Veis_0127	1.315e-23	108.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,2VRSQ@28216|Betaproteobacteria,4ADXN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
DYD1_k127_6666926_12	573064.Mefer_0948	4.694e-47	175.0	COG1102@1|root,arCOG01037@2157|Archaea,2XWPB@28890|Euryarchaeota,23QTJ@183939|Methanococci	183939|Methanococci	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DYD1_k127_6666926_15	673860.AciM339_1123	2.397e-29	128.0	COG1422@1|root,arCOG02673@2157|Archaea,2XZDK@28890|Euryarchaeota,3F2U5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Integral membrane protein DUF106	-	-	-	-	-	-	-	-	-	-	-	-	DUF106
DYD1_k127_6666926_11	386456.JQKN01000001_gene1738	1.98e-48	180.0	COG2019@1|root,arCOG01039@2157|Archaea,2XVK7@28890|Euryarchaeota,23NZH@183925|Methanobacteria	183925|Methanobacteria	F	Belongs to the archaeal adenylate kinase family	adkA	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
DYD1_k127_6666926_18	1009370.ALO_08800	9.594e-15	83.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4H2B0@909932|Negativicutes	909932|Negativicutes	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DYD1_k127_6666926_24	1047013.AQSP01000066_gene724	2.078e-07	56.0	2E5PY@1|root,330EK@2|Bacteria,2NS29@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_6666926_7	868131.MSWAN_1886	2.142e-87	314.0	COG1193@1|root,arCOG02895@2157|Archaea,2XT51@28890|Euryarchaeota,23NQB@183925|Methanobacteria	183925|Methanobacteria	L	Has ATPase and non-specific DNA-binding activities	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH_5,MutS_V
DYD1_k127_6666926_23	502025.Hoch_3526	1.292e-09	65.0	COG1765@1|root,COG1765@2|Bacteria,1Q5AG@1224|Proteobacteria,430PG@68525|delta/epsilon subdivisions,2WW27@28221|Deltaproteobacteria,2YVNY@29|Myxococcales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DYD1_k127_6666926_8	1415778.JQMM01000001_gene2133	9.83e-63	230.0	COG3199@1|root,COG3199@2|Bacteria,1MY3J@1224|Proteobacteria,1RP9X@1236|Gammaproteobacteria,1J4E9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	ATP-NAD kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
DYD1_k127_6666926_1	529709.PYCH_18260	1.615e-167	544.0	COG1003@1|root,arCOG00076@2157|Archaea,2XT3V@28890|Euryarchaeota,242MV@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
DYD1_k127_6666926_4	1042877.GQS_03935	1.47e-116	392.0	COG0403@1|root,arCOG00077@2157|Archaea,2XT39@28890|Euryarchaeota,242SE@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
DYD1_k127_6666926_27	751944.HALDL1_12075	5.1e-05	49.0	arCOG09272@1|root,arCOG09272@2157|Archaea,2Y0E6@28890|Euryarchaeota,23XJ9@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_6666926_2	649747.HMPREF0083_03329	8.633e-165	529.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,26QD2@186822|Paenibacillaceae	91061|Bacilli	C	Malic enzyme	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
DYD1_k127_6666926_29	58123.JOFJ01000016_gene4115	0.0002904	53.0	COG4409@1|root,COG4409@2|Bacteria,2GNDG@201174|Actinobacteria	201174|Actinobacteria	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,RicinB_lectin_2
DYD1_k127_6666926_14	192952.MM_0247	4.198e-38	154.0	COG3620@1|root,arCOG00608@2157|Archaea,2XTDG@28890|Euryarchaeota,2N9J9@224756|Methanomicrobia	224756|Methanomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A2079	CBS,HTH_3
DYD1_k127_6666926_0	673860.AciM339_0956	3.911e-210	677.0	COG0143@1|root,arCOG00810@2157|Archaea,2XTG5@28890|Euryarchaeota,3F2F7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A0543	Anticodon_1,tRNA-synt_1g,tRNA_bind
DYD1_k127_6666926_25	797114.C475_01062	4.049e-07	57.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
DYD1_k127_6666926_28	345341.KUTG_08254	0.0002643	53.0	COG4409@1|root,COG4409@2|Bacteria,2ICIA@201174|Actinobacteria,4EBQC@85010|Pseudonocardiales	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
DYD1_k127_6666926_21	2074.JNYD01000004_gene4675	5.649e-12	73.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4E0DD@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	nudL	-	-	ko:K18568	ko00332,ko01130,map00332,map01130	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
DYD1_k127_6719224_0	345341.KUTG_03299	5.407e-125	410.0	COG3177@1|root,COG3177@2|Bacteria,2GN3K@201174|Actinobacteria,4E3SI@85010|Pseudonocardiales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
DYD1_k127_6719224_2	1122182.KB903825_gene590	1.724e-12	76.0	COG0500@1|root,COG2226@2|Bacteria,2I7M1@201174|Actinobacteria,4DJV5@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DYD1_k127_6719224_4	1347086.CCBA010000046_gene2441	0.0001744	49.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,1ZF6G@1386|Bacillus	91061|Bacilli	T	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
DYD1_k127_6719224_1	105422.BBPM01000034_gene1228	6.64e-49	176.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria,2NIJU@228398|Streptacidiphilus	201174|Actinobacteria	T	STAS domain	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
DYD1_k127_6719224_3	1123072.AUDH01000001_gene3167	8.575e-05	52.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,2JQBM@204441|Rhodospirillales	204441|Rhodospirillales	G	phosphomannomutase	exoC	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DYD1_k127_677944_34	1278307.KB907059_gene2689	1.956e-14	74.0	COG0346@1|root,COG0346@2|Bacteria,1N0CH@1224|Proteobacteria,1S8U7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DYD1_k127_677944_30	1286631.X805_30960	4.779e-28	126.0	COG1404@1|root,COG1520@1|root,COG5640@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K14645,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,PQQ_2,Peptidase_S8,SBBP
DYD1_k127_677944_31	1504981.KO116_2305	7.573e-21	98.0	COG5654@1|root,COG5654@2|Bacteria,1N6P3@1224|Proteobacteria,1S7EU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RES
DYD1_k127_677944_36	571.MC52_00625	3.244e-13	79.0	COG5642@1|root,COG5642@2|Bacteria,1RJWF@1224|Proteobacteria,1S6CI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
DYD1_k127_677944_42	290399.Arth_2203	3.744e-09	63.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	traP	GO:0005575,GO:0016020	1.14.99.57,6.2.1.3	ko:K01897,ko:K21481	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	ABM
DYD1_k127_677944_7	1242864.D187_009751	1.055e-98	325.0	COG0262@1|root,COG0262@2|Bacteria,1QH1Q@1224|Proteobacteria	1224|Proteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
DYD1_k127_677944_19	1453501.JELR01000002_gene810	1.725e-50	181.0	COG4898@1|root,COG4898@2|Bacteria,1RHGW@1224|Proteobacteria,1S7UZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
DYD1_k127_677944_41	585530.HMPREF0183_1990	1.007e-09	65.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
DYD1_k127_677944_47	439481.Aboo_0364	0.0002422	53.0	COG1522@1|root,arCOG01586@2157|Archaea,2Y6Z8@28890|Euryarchaeota,3F2Z8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
DYD1_k127_677944_13	1121935.AQXX01000078_gene1575	4.564e-70	241.0	COG3607@1|root,COG3607@2|Bacteria,1RH1T@1224|Proteobacteria,1S6XB@1236|Gammaproteobacteria,1XK53@135619|Oceanospirillales	135619|Oceanospirillales	S	Lactoylglutathione lyase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	-
DYD1_k127_677944_49	40571.JOEA01000005_gene4257	0.0007648	49.0	COG5637@1|root,COG5637@2|Bacteria,2I3U7@201174|Actinobacteria,4E5IY@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DYD1_k127_677944_28	1120965.AUBV01000003_gene485	2.326e-30	122.0	COG0346@1|root,COG0346@2|Bacteria,4NRRY@976|Bacteroidetes,47VMR@768503|Cytophagia	976|Bacteroidetes	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DYD1_k127_677944_45	797210.Halxa_2835	9.276e-05	54.0	COG1522@1|root,arCOG01583@2157|Archaea,2XXSY@28890|Euryarchaeota,23W43@183963|Halobacteria	183963|Halobacteria	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_677944_44	1054860.KB913030_gene481	2.761e-07	60.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_3
DYD1_k127_677944_23	1246995.AFR_31765	1.024e-37	162.0	COG2936@1|root,COG2936@2|Bacteria,2GJ2K@201174|Actinobacteria,4DC1G@85008|Micromonosporales	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	pepX	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
DYD1_k127_677944_25	1307761.L21SP2_1543	4.996e-35	139.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	COXG,Polyketide_cyc2
DYD1_k127_677944_21	1254432.SCE1572_33400	5.799e-46	184.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL,VCBS
DYD1_k127_677944_14	143224.JQMD01000002_gene3060	2.817e-63	235.0	COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1HZYM@117743|Flavobacteriia	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	LeuA_dimer,PALP
DYD1_k127_677944_33	886379.AEWI01000033_gene2744	6.121e-16	91.0	COG0454@1|root,COG0456@2|Bacteria,4NQ9E@976|Bacteroidetes,2FY34@200643|Bacteroidia,3XKQN@558415|Marinilabiliaceae	976|Bacteroidetes	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DYD1_k127_677944_27	797299.HALLA_00875	1.453e-30	126.0	COG0640@1|root,arCOG01681@2157|Archaea,2XYB2@28890|Euryarchaeota,23WKI@183963|Halobacteria	2157|Archaea	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD1_k127_677944_16	935863.AWZR01000004_gene399	3.709e-55	197.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,1S4M7@1236|Gammaproteobacteria,1X6D4@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DYD1_k127_677944_24	1123008.KB905701_gene2170	2.401e-37	145.0	COG2764@1|root,COG2764@2|Bacteria,4NQD7@976|Bacteroidetes,2FU3D@200643|Bacteroidia,22YFY@171551|Porphyromonadaceae	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
DYD1_k127_677944_12	869210.Marky_0500	2.648e-78	278.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DYD1_k127_677944_48	1229909.NSED_06400	0.0003162	49.0	COG3794@1|root,arCOG08764@1|root,arCOG02926@2157|Archaea,arCOG08764@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD1_k127_677944_29	1380390.JIAT01000009_gene991	1.031e-28	133.0	COG3794@1|root,COG3794@2|Bacteria,2HQ6D@201174|Actinobacteria,4CRPC@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_677944_18	266779.Meso_0627	1.813e-51	189.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2U9AG@28211|Alphaproteobacteria,43PGY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
DYD1_k127_677944_8	1231391.AMZF01000032_gene639	2.878e-93	312.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,3T3XE@506|Alcaligenaceae	28216|Betaproteobacteria	L	3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DYD1_k127_677944_37	1192034.CAP_8788	4.414e-13	78.0	COG0625@1|root,COG0625@2|Bacteria,1RC4Y@1224|Proteobacteria,43186@68525|delta/epsilon subdivisions,2WWCF@28221|Deltaproteobacteria,2YVW8@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
DYD1_k127_677944_32	679926.Mpet_1097	1.282e-18	91.0	COG1733@1|root,arCOG01057@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD1_k127_677944_35	234267.Acid_4278	9.155e-14	83.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
DYD1_k127_677944_6	985053.VMUT_1280	3.188e-110	372.0	COG0069@1|root,arCOG00619@2157|Archaea	2157|Archaea	E	Belongs to the glutamate synthase family	-	-	1.13.12.4	ko:K00467	ko00620,map00620	-	R00319	RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh,Glu_synthase
DYD1_k127_677944_5	384616.Pisl_0757	5.745e-115	381.0	COG0017@1|root,arCOG00409@2157|Archaea,2XPWE@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM tRNA synthetase, class II (D, K and N)	-	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2
DYD1_k127_677944_26	342949.PNA2_0890	1.777e-33	134.0	COG1522@1|root,arCOG01580@2157|Archaea,2XX9F@28890|Euryarchaeota,243Z9@183968|Thermococci	183968|Thermococci	K	transcription regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
DYD1_k127_677944_15	391625.PPSIR1_09565	2.28e-59	210.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
DYD1_k127_677944_0	929562.Emtol_3651	2.109e-202	643.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DYD1_k127_677944_3	1499680.CCFE01000024_gene2901	4.16e-141	465.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus	91061|Bacilli	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	pdhD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
DYD1_k127_677944_2	405948.SACE_5330	1.272e-153	498.0	COG3391@1|root,COG3391@2|Bacteria,2GXCN@201174|Actinobacteria,4E1YZ@85010|Pseudonocardiales	201174|Actinobacteria	S	serine threonine protein kinase	pkn32	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
DYD1_k127_677944_4	1267534.KB906759_gene1728	8.298e-117	396.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	PFOR_II,POR,POR_N,Transketolase_C
DYD1_k127_677944_9	178306.PAE1558	5.779e-92	311.0	COG1013@1|root,arCOG01599@2157|Archaea,2XPQG@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
DYD1_k127_677944_17	1519464.HY22_00525	2.508e-52	196.0	COG1028@1|root,COG1028@2|Bacteria	1519464.HY22_00525|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_677944_1	673860.AciM339_1547	7.379e-168	549.0	COG0466@1|root,arCOG02160@2157|Archaea,2XTT0@28890|Euryarchaeota,3F2HW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Belongs to the peptidase S16 family	lon	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
DYD1_k127_677944_46	679926.Mpet_1784	0.0002069	54.0	COG3398@1|root,arCOG02611@2157|Archaea,2XV4M@28890|Euryarchaeota,2NB4N@224756|Methanomicrobia	224756|Methanomicrobia	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_677944_39	1121374.KB891591_gene3526	1.437e-10	66.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
DYD1_k127_677944_10	1236689.MMALV_08840	1.288e-83	287.0	COG1961@1|root,arCOG03162@2157|Archaea,2Y10R@28890|Euryarchaeota,3F3I5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Recombinase,Resolvase
DYD1_k127_677944_11	404589.Anae109_0447	1.284e-82	282.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2YURC@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DYD1_k127_677944_43	861299.J421_6130	1.733e-08	61.0	COG0662@1|root,COG0662@2|Bacteria,1ZVA1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DYD1_k127_677944_20	589924.Ferp_2003	1.107e-47	182.0	COG0311@1|root,arCOG00034@2157|Archaea,2XTZS@28890|Euryarchaeota,245QR@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
DYD1_k127_6954361_17	1144275.COCOR_02883	6.67e-11	75.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,430Q8@68525|delta/epsilon subdivisions,2WVYQ@28221|Deltaproteobacteria,2YU06@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
DYD1_k127_6954361_6	673860.AciM339_0523	1.975e-66	233.0	COG0463@1|root,arCOG00894@2157|Archaea,2XUJ6@28890|Euryarchaeota,3F38U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD1_k127_6954361_20	797302.Halru_2631	1.178e-05	51.0	arCOG07990@1|root,arCOG07990@2157|Archaea,2XZ08@28890|Euryarchaeota,23X6V@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_6954361_13	1227497.C491_06923	3.389e-19	93.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
DYD1_k127_6954361_16	187272.Mlg_2280	2.566e-11	72.0	COG1556@1|root,COG1556@2|Bacteria,1R4TE@1224|Proteobacteria,1S6IK@1236|Gammaproteobacteria,1WZ86@135613|Chromatiales	135613|Chromatiales	S	Pfam:DUF162	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
DYD1_k127_6954361_3	1521187.JPIM01000077_gene1101	5.507e-128	424.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2G665@200795|Chloroflexi,37659@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM iron-sulfur cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_7,Fer4_8,LUD_dom
DYD1_k127_6954361_8	1231185.BAMP01000020_gene2821	1.01e-53	197.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,43JAC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
DYD1_k127_6954361_9	673860.AciM339_0095	1.517e-51	192.0	COG1859@1|root,arCOG04063@2157|Archaea,2XWPC@28890|Euryarchaeota,3F2KG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
DYD1_k127_6954361_12	867845.KI911784_gene2901	8.223e-32	132.0	COG0241@1|root,COG0241@2|Bacteria,2G6V8@200795|Chloroflexi,375WG@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM histidinol-phosphate phosphatase family protein	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
DYD1_k127_6954361_4	1236689.MMALV_07230	7.947e-95	327.0	COG0520@1|root,arCOG00065@2157|Archaea,2XSYI@28890|Euryarchaeota	2157|Archaea	E	Cysteine desulfurase	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DYD1_k127_6954361_19	456442.Mboo_1986	3.109e-06	56.0	arCOG09483@1|root,arCOG09483@2157|Archaea	2157|Archaea	-	-	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
DYD1_k127_6954361_11	446468.Ndas_1018	3.371e-39	152.0	COG3476@1|root,COG3476@2|Bacteria,2IQA5@201174|Actinobacteria,4EK5D@85012|Streptosporangiales	201174|Actinobacteria	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
DYD1_k127_6954361_14	693661.Arcve_0149	1.313e-17	89.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_6954361_7	521011.Mpal_1938	2.098e-56	208.0	COG0301@1|root,arCOG00038@2157|Archaea,2XYMB@28890|Euryarchaeota,2NBHY@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiI
DYD1_k127_6954361_18	713586.KB900536_gene1761	4.104e-09	62.0	COG1977@1|root,COG1977@2|Bacteria,1NHG7@1224|Proteobacteria,1TK6F@1236|Gammaproteobacteria,1WZUM@135613|Chromatiales	135613|Chromatiales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DYD1_k127_6954361_1	1041930.Mtc_0469	0.0	1059.0	COG1933@1|root,arCOG04447@2157|Archaea,2XU5S@28890|Euryarchaeota,2N91E@224756|Methanomicrobia	224756|Methanomicrobia	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
DYD1_k127_6954361_10	644966.Tmar_1098	1.774e-46	180.0	COG0005@1|root,COG1846@1|root,COG0005@2|Bacteria,COG1846@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,3WDE1@538999|Clostridiales incertae sedis	186801|Clostridia	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	mtaP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
DYD1_k127_6954361_15	314230.DSM3645_01786	3.885e-13	82.0	COG1547@1|root,COG1547@2|Bacteria,2J0XW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
DYD1_k127_6954361_5	93220.LV28_02540	7.56e-68	261.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,1K590@119060|Burkholderiaceae	28216|Betaproteobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
DYD1_k127_6954361_2	485913.Krac_12092	2.241e-215	680.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DYD1_k127_6954361_0	204669.Acid345_0465	0.0	1457.0	COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria,2JHJH@204432|Acidobacteriia	204432|Acidobacteriia	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
DYD1_k127_6960733_3	269799.Gmet_0095	6.134e-26	110.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,42P41@68525|delta/epsilon subdivisions,2WM40@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DYD1_k127_6960733_0	1408424.JHYI01000007_gene1485	1.11e-221	701.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus	91061|Bacilli	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yhcX	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
DYD1_k127_6960733_4	439481.Aboo_1076	4.112e-15	77.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75G@28890|Euryarchaeota,3F3FD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
DYD1_k127_6960733_1	273116.14324779	8.382e-60	216.0	COG0202@1|root,arCOG04241@2157|Archaea,2XTQB@28890|Euryarchaeota,241P6@183967|Thermoplasmata	183967|Thermoplasmata	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoD	-	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_A_bac,RNA_pol_L
DYD1_k127_6960733_2	1151117.AJLF01000002_gene19	1.001e-59	209.0	COG0100@1|root,arCOG04240@2157|Archaea,2XX1S@28890|Euryarchaeota,243ZQ@183968|Thermococci	183968|Thermococci	J	Located on the platform of the 30S subunit	rps11	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DYD1_k127_6973756_0	981085.XP_010099728.1	0.0001577	53.0	COG2256@1|root,KOG2028@2759|Eukaryota,37PNU@33090|Viridiplantae,3G93Y@35493|Streptophyta,4JDB7@91835|fabids	35493|Streptophyta	L	ATPase WRNIP1-like	-	GO:0000731,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006275,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030174,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071897,GO:0080090,GO:0090304,GO:0090329,GO:1901360,GO:1901362,GO:1901576,GO:2000112	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,UBA
DYD1_k127_712046_51	1121877.JQKF01000002_gene1725	3.29e-18	93.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CNHR@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II
DYD1_k127_712046_10	1121920.AUAU01000031_gene1410	3.802e-121	399.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	-	-	1.2.1.12,1.2.1.59,1.4.1.16	ko:K00134,ko:K00150,ko:K03340	ko00010,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00526,M00552	R01061,R01063,R02755	RC00006,RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	DapB_N,Gp_dh_C,Gp_dh_N
DYD1_k127_712046_41	444157.Tneu_1020	9.714e-30	128.0	COG0494@1|root,arCOG01078@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DYD1_k127_712046_32	1415779.JOMH01000001_gene502	2.199e-40	162.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,1S6M1@1236|Gammaproteobacteria,1XAJC@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
DYD1_k127_712046_65	1330700.JQNC01000003_gene546	2.523e-08	67.0	COG4867@1|root,COG4867@2|Bacteria,1WJ6Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein with a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
DYD1_k127_712046_60	1223545.GS4_11_01520	5.226e-11	76.0	COG0714@1|root,COG0714@2|Bacteria,2GMBP@201174|Actinobacteria,4GCX8@85026|Gordoniaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,VWA_CoxE
DYD1_k127_712046_22	273116.14324753	6.013e-64	230.0	COG0010@1|root,arCOG01700@2157|Archaea,2XTEP@28890|Euryarchaeota,241N8@183967|Thermoplasmata	183967|Thermoplasmata	E	Arginase family	-	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DYD1_k127_712046_63	485914.Hmuk_0316	8.82e-09	68.0	COG5276@1|root,arCOG02565@2157|Archaea,2XV6J@28890|Euryarchaeota,23SNQ@183963|Halobacteria	183963|Halobacteria	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD1_k127_712046_34	693661.Arcve_1213	7.059e-39	150.0	COG0231@1|root,arCOG04277@2157|Archaea,2XX3E@28890|Euryarchaeota	28890|Euryarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	EFP_N,eIF-5a
DYD1_k127_712046_70	1155718.KB891940_gene4697	7.948e-05	54.0	COG1522@1|root,COG1522@2|Bacteria,2GKP4@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
DYD1_k127_712046_23	679926.Mpet_0765	8.177e-64	235.0	COG3276@1|root,arCOG01564@2157|Archaea,2XWBV@28890|Euryarchaeota,2N945@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM elongation factor Tu domain 2	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
DYD1_k127_712046_69	1530186.JQEY01000001_gene673	6.979e-05	53.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2U1NG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Aldolase	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
DYD1_k127_712046_19	673860.AciM339_1573	5.534e-74	260.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
DYD1_k127_712046_62	523850.TON_0811	1.913e-09	66.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,2440W@183968|Thermococci	28890|Euryarchaeota	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_5
DYD1_k127_712046_39	589924.Ferp_1305	2.971e-30	127.0	COG0237@1|root,arCOG01045@2157|Archaea,2XWNJ@28890|Euryarchaeota,245NW@183980|Archaeoglobi	183980|Archaeoglobi	H	Belongs to the UPF0200 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17,RNA_binding
DYD1_k127_712046_55	485914.Hmuk_1264	2.692e-12	75.0	COG1931@1|root,arCOG01043@2157|Archaea,2XWHA@28890|Euryarchaeota,23VAH@183963|Halobacteria	183963|Halobacteria	S	Belongs to the UPF0201 family	-	-	-	ko:K09736	-	-	-	-	ko00000	-	-	-	RNA_binding
DYD1_k127_712046_43	224719.Abm4_0786	2.528e-26	119.0	COG1082@1|root,arCOG01895@2157|Archaea,2XUTU@28890|Euryarchaeota,23PJC@183925|Methanobacteria	183925|Methanobacteria	G	Sugar phosphate isomerase epimerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
DYD1_k127_712046_18	1132509.C447_03226	3.188e-76	266.0	COG1234@1|root,arCOG00501@2157|Archaea,2XTJ9@28890|Euryarchaeota,23SER@183963|Halobacteria	183963|Halobacteria	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
DYD1_k127_712046_38	1236689.MMALV_16250	1.748e-31	134.0	COG0560@1|root,arCOG01158@2157|Archaea	2157|Archaea	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase,Hydrolase_3
DYD1_k127_712046_71	1047013.AQSP01000066_gene724	8.93e-05	47.0	2E5PY@1|root,330EK@2|Bacteria,2NS29@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_712046_11	797209.ZOD2009_03350	2.235e-111	373.0	COG0446@1|root,arCOG01070@2157|Archaea,2XTPB@28890|Euryarchaeota,23TGY@183963|Halobacteria	183963|Halobacteria	S	NAD(FAD)-dependent dehydrogenases	noxA2	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
DYD1_k127_712046_47	390874.Tpet_0667	2.605e-24	115.0	COG3481@1|root,COG3481@2|Bacteria,2GC74@200918|Thermotogae	200918|Thermotogae	S	nucleic acid binding OB-fold tRNA helicase-type	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
DYD1_k127_712046_59	1123060.JONP01000009_gene1965	4.249e-11	72.0	COG1853@1|root,COG1853@2|Bacteria,1MUPP@1224|Proteobacteria,2VERI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Flavin reductase like domain	MA20_21390	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DYD1_k127_712046_72	497964.CfE428DRAFT_0641	0.000109	53.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
DYD1_k127_712046_50	211114.JOEF01000002_gene4151	2.346e-18	90.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4E1TR@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
DYD1_k127_712046_64	292459.STH2095	9.802e-09	61.0	COG5349@1|root,COG5349@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF983)	MA20_36345	-	-	-	-	-	-	-	-	-	-	-	DUF983
DYD1_k127_712046_27	1191523.MROS_1983	7.433e-53	194.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DYD1_k127_712046_5	1094980.Mpsy_1728	1.604e-160	515.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,2N983@224756|Methanomicrobia	224756|Methanomicrobia	L	Involved in regulation of DNA replication	cdc6-1	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22,Cdc6_C
DYD1_k127_712046_13	404589.Anae109_3194	2.922e-100	336.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,42Q1N@68525|delta/epsilon subdivisions,2WK3A@28221|Deltaproteobacteria,2Z377@29|Myxococcales	28221|Deltaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
DYD1_k127_712046_58	268739.Nmlp_3924	2.057e-11	75.0	COG0681@1|root,arCOG01739@2157|Archaea,2XU45@28890|Euryarchaeota,23U0G@183963|Halobacteria	183963|Halobacteria	U	COG0681 Signal peptidase I	sec11	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DYD1_k127_712046_49	673860.AciM339_0002	1.318e-19	100.0	COG0681@1|root,arCOG01739@2157|Archaea,2Y6XH@28890|Euryarchaeota,3F2QN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
DYD1_k127_712046_61	224325.AF_1791	1.187e-09	71.0	COG0681@1|root,arCOG01739@2157|Archaea,2XU45@28890|Euryarchaeota,2470A@183980|Archaeoglobi	183980|Archaeoglobi	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DYD1_k127_712046_14	351160.RCIX1121	6.795e-99	349.0	COG1311@1|root,arCOG04455@2157|Archaea,2XSUG@28890|Euryarchaeota,2N96N@224756|Methanomicrobia	224756|Methanomicrobia	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B,Metallophos,tRNA_anti-codon
DYD1_k127_712046_57	444157.Tneu_1865	8.082e-12	76.0	COG0608@1|root,arCOG00424@2157|Archaea,2XPR0@28889|Crenarchaeota	28889|Crenarchaeota	L	phosphoesterase RecJ domain protein	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHH,DHHA1
DYD1_k127_712046_73	1200792.AKYF01000026_gene163	0.0006241	51.0	COG4932@1|root,COG4932@2|Bacteria,1UJQY@1239|Firmicutes,4ITDJ@91061|Bacilli,270X3@186822|Paenibacillaceae	91061|Bacilli	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
DYD1_k127_712046_74	863365.XHC_2528	0.0007022	51.0	COG1629@1|root,COG4771@2|Bacteria,1PSM0@1224|Proteobacteria,1T0NW@1236|Gammaproteobacteria,1X3X1@135614|Xanthomonadales	135614|Xanthomonadales	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
DYD1_k127_712046_68	1166018.FAES_5200	3.236e-05	55.0	COG1470@1|root,COG4773@1|root,COG1470@2|Bacteria,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,47NDE@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent siderophore receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD1_k127_712046_25	1382306.JNIM01000001_gene2829	5.852e-56	211.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N,Peptidase_S8
DYD1_k127_712046_31	316274.Haur_3591	4.963e-43	171.0	COG4948@1|root,COG4948@2|Bacteria,2G882@200795|Chloroflexi,3757P@32061|Chloroflexia	2|Bacteria	M	mandelate racemase muconate lactonizing	ycjG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	iEC042_1314.EC042_1441,iECUMN_1333.ECUMN_1620	MR_MLE_C,MR_MLE_N
DYD1_k127_712046_42	710421.Mycch_1193	3.229e-28	127.0	COG2373@1|root,COG3391@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2GK45@201174|Actinobacteria,2366T@1762|Mycobacteriaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Lactonase
DYD1_k127_712046_9	1236689.MMALV_07730	1.629e-127	424.0	COG0015@1|root,arCOG01747@2157|Archaea,2XUQ5@28890|Euryarchaeota,3F2GT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
DYD1_k127_712046_53	288000.BBta_4566	1.284e-13	81.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,3JRP5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	MA20_37085	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DYD1_k127_712046_15	589924.Ferp_2205	2.435e-87	302.0	COG0075@1|root,arCOG00082@2157|Archaea,2XTWU@28890|Euryarchaeota,245V2@183980|Archaeoglobi	183980|Archaeoglobi	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DYD1_k127_712046_29	419665.Maeo_0103	1.258e-44	169.0	COG0041@1|root,arCOG02464@2157|Archaea,2XU0P@28890|Euryarchaeota,23QSX@183939|Methanococci	183939|Methanococci	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DYD1_k127_712046_16	760568.Desku_3442	1.471e-84	291.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,26028@186807|Peptococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
DYD1_k127_712046_44	43989.cce_1810	4.281e-26	113.0	COG0278@1|root,COG0278@2|Bacteria,1G6JA@1117|Cyanobacteria,3KI4T@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	ycf64	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
DYD1_k127_712046_56	197221.22294597	5.951e-12	72.0	COG0271@1|root,COG0271@2|Bacteria,1G7V3@1117|Cyanobacteria	1117|Cyanobacteria	T	Belongs to the BolA IbaG family	colA	-	-	-	-	-	-	-	-	-	-	-	BolA
DYD1_k127_712046_36	452637.Oter_4528	3.582e-37	154.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,3K9P3@414999|Opitutae	414999|Opitutae	S	PFAM nuclear protein SET	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
DYD1_k127_712046_45	948106.AWZT01000003_gene5809	5.778e-26	120.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2VR5U@28216|Betaproteobacteria,1K2B1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Nuclear protein SET	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
DYD1_k127_712046_2	485913.Krac_12013	4.174e-226	715.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DYD1_k127_712046_3	1329516.JPST01000008_gene2032	1.932e-179	571.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,27B4J@186824|Thermoactinomycetaceae	91061|Bacilli	G	Enolase, N-terminal domain	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DYD1_k127_712046_21	1268237.G114_05905	2.503e-66	234.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,1RNBU@1236|Gammaproteobacteria,1Y46F@135624|Aeromonadales	135624|Aeromonadales	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
DYD1_k127_712046_30	1125863.JAFN01000001_gene880	4.899e-43	163.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DYD1_k127_712046_0	1041930.Mtc_2296	1.08e-251	812.0	COG0495@1|root,arCOG00809@2157|Archaea,2XU7M@28890|Euryarchaeota,2N99R@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
DYD1_k127_712046_24	673860.AciM339_1503	1.335e-63	228.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,3F2P1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
DYD1_k127_712046_26	215803.DB30_0480	2.406e-54	203.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43A9Z@68525|delta/epsilon subdivisions,2X37W@28221|Deltaproteobacteria,2YV2G@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
DYD1_k127_712046_54	1261545.MBE-HAL_1494	2.044e-13	79.0	COG3613@1|root,arCOG02434@2157|Archaea,2XZZI@28890|Euryarchaeota,2406H@183963|Halobacteria	183963|Halobacteria	F	Nucleoside 2-deoxyribosyltransferase like	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
DYD1_k127_712046_7	1219084.AP014508_gene1417	5.477e-140	466.0	COG0405@1|root,COG0405@2|Bacteria,2GCYN@200918|Thermotogae	200918|Thermotogae	M	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
DYD1_k127_712046_35	673860.AciM339_0274	2.094e-38	153.0	COG2125@1|root,arCOG01946@2157|Archaea,2XXZJ@28890|Euryarchaeota,3F2RJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
DYD1_k127_712046_4	797210.Halxa_3493	1.816e-166	532.0	COG3276@1|root,arCOG01563@2157|Archaea,2XUKU@28890|Euryarchaeota,23SWR@183963|Halobacteria	183963|Halobacteria	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2g	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,eIF2_C
DYD1_k127_712046_66	195522.BD01_2032	1.293e-07	58.0	COG1412@1|root,arCOG04312@2157|Archaea,2XZ0Z@28890|Euryarchaeota,2441K@183968|Thermococci	183968|Thermococci	V	Fcf1	-	-	-	ko:K07158	-	-	-	-	ko00000	-	-	-	Fcf1
DYD1_k127_712046_28	1382304.JNIL01000001_gene632	7.97e-51	196.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,27A7C@186823|Alicyclobacillaceae	91061|Bacilli	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
DYD1_k127_712046_48	1120953.AUBH01000011_gene514	1.91e-23	105.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,4685Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
DYD1_k127_712046_12	312153.Pnuc_1818	1.149e-109	366.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,1JZZF@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DYD1_k127_712046_8	192952.MM_1974	1.209e-138	463.0	COG1243@1|root,arCOG01361@2157|Archaea,2XT9Z@28890|Euryarchaeota,2N9D5@224756|Methanomicrobia	224756|Methanomicrobia	K	TIGRFAM histone acetyltransferase, ELP3 family	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
DYD1_k127_712046_33	518766.Rmar_1438	3.151e-40	172.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1438|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_712046_20	1267535.KB906767_gene5368	1.303e-68	263.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene5368|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_712046_17	518766.Rmar_1438	1.338e-78	292.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1438|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_712046_52	1120960.ATXG01000001_gene636	5.431e-17	96.0	COG3250@1|root,COG3386@1|root,COG4733@1|root,COG3250@2|Bacteria,COG3386@2|Bacteria,COG4733@2|Bacteria,2I3FI@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
DYD1_k127_712046_1	1449347.JQLN01000004_gene6453	1.69e-238	787.0	COG2132@1|root,COG2132@2|Bacteria,2IDP7@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
DYD1_k127_712046_40	368407.Memar_1026	3.004e-30	128.0	COG0500@1|root,arCOG04989@2157|Archaea,2Y0ZS@28890|Euryarchaeota,2N9SX@224756|Methanomicrobia	224756|Methanomicrobia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DYD1_k127_712046_6	562970.Btus_3274	1.989e-148	481.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,277WW@186823|Alicyclobacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD1_k127_712046_37	1380390.JIAT01000012_gene3302	1.587e-31	138.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_848131_0	304371.MCP_1049	3.463e-55	207.0	COG0144@1|root,arCOG00973@2157|Archaea,2XUFZ@28890|Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016427,GO:0016428,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
DYD1_k127_91664_0	268739.Nmlp_2861	1.19e-23	108.0	COG0063@1|root,arCOG00018@2157|Archaea,2XU4W@28890|Euryarchaeota,23TNP@183963|Halobacteria	183963|Halobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
DYD1_k127_933621_135	408672.NBCG_05648	2.803e-05	55.0	2C75R@1|root,2ZCK5@2|Bacteria,2IBVD@201174|Actinobacteria,4DTXA@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_24	243231.GSU2091	7.838e-112	370.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,43UB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DYD1_k127_933621_128	192952.MM_2605	1.996e-07	56.0	COG2026@1|root,arCOG01665@2157|Archaea	2157|Archaea	DJ	PFAM plasmid stabilization system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
DYD1_k127_933621_79	1132509.C447_15421	5.187e-37	148.0	COG1901@1|root,arCOG01239@2157|Archaea,2XTSB@28890|Euryarchaeota,23RZ7@183963|Halobacteria	183963|Halobacteria	J	Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs	trmY	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.257	ko:K16317	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_2
DYD1_k127_933621_11	439481.Aboo_0917	7.905e-144	469.0	COG0541@1|root,arCOG01228@2157|Archaea,2XTWX@28890|Euryarchaeota,3F2HD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DYD1_k127_933621_121	1123507.ATVQ01000001_gene2038	4.563e-10	73.0	COG0681@1|root,COG0681@2|Bacteria,2IIF5@201174|Actinobacteria,1W9R7@1268|Micrococcaceae	201174|Actinobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DYD1_k127_933621_120	693661.Arcve_1632	4.439e-10	66.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
DYD1_k127_933621_82	1525715.IX54_06810	2.403e-32	137.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TSI2@28211|Alphaproteobacteria,2PWME@265|Paracoccus	28211|Alphaproteobacteria	V	ATPases associated with a variety of cellular activities	nosF	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
DYD1_k127_933621_126	1304888.ATWF01000002_gene505	1.239e-08	64.0	COG2386@1|root,COG2386@2|Bacteria,2GF4W@200930|Deferribacteres	200930|Deferribacteres	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
DYD1_k127_933621_117	526222.Desal_1543	1.758e-10	72.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,42RU4@68525|delta/epsilon subdivisions,2WNN7@28221|Deltaproteobacteria,2M9X3@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
DYD1_k127_933621_103	1094980.Mpsy_3178	2.939e-18	88.0	COG0755@1|root,arCOG00267@2157|Archaea,2XXKZ@28890|Euryarchaeota,2NA4P@224756|Methanomicrobia	224756|Methanomicrobia	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
DYD1_k127_933621_140	1304872.JAGC01000009_gene1207	0.0006629	48.0	COG2332@1|root,COG2332@2|Bacteria,1PZFU@1224|Proteobacteria,42U7H@68525|delta/epsilon subdivisions,2WQ19@28221|Deltaproteobacteria,2MC51@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
DYD1_k127_933621_65	1094980.Mpsy_1084	7.89e-45	186.0	COG1138@1|root,arCOG00270@2157|Archaea,2XUDS@28890|Euryarchaeota,2NADH@224756|Methanomicrobia	224756|Methanomicrobia	O	Cytochrome C assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	Cytochrom_C_asm
DYD1_k127_933621_72	1511.CLOST_1920	8.391e-41	162.0	COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,25RKY@186804|Peptostreptococcaceae	186801|Clostridia	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
DYD1_k127_933621_80	1261545.MBE-HAL_0760	1.174e-34	142.0	COG0537@1|root,arCOG00419@2157|Archaea,2XXWC@28890|Euryarchaeota,23V8Q@183963|Halobacteria	183963|Halobacteria	F	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hit2	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DYD1_k127_933621_21	673860.AciM339_0753	4.272e-116	415.0	COG1287@1|root,arCOG02044@2157|Archaea,arCOG05365@2157|Archaea,2Y7QJ@28890|Euryarchaeota,3F2NE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Carboxypeptidase regulatory-like domain	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	CarboxypepD_reg,PMT_2,STT3
DYD1_k127_933621_22	1459636.NTE_01784	1.641e-114	386.0	COG0147@1|root,arCOG02014@2157|Archaea,41S8W@651137|Thaumarchaeota	651137|Thaumarchaeota	E	component I	-	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DYD1_k127_933621_51	1382356.JQMP01000004_gene441	6.657e-64	228.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,27Y8S@189775|Thermomicrobia	189775|Thermomicrobia	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DYD1_k127_933621_31	635013.TherJR_1605	5.01e-92	315.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,2600U@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
DYD1_k127_933621_90	937777.Deipe_3352	6.142e-27	127.0	COG0134@1|root,COG0134@2|Bacteria,1WI5W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
DYD1_k127_933621_101	1333523.L593_08835	9.069e-21	107.0	COG0135@1|root,arCOG01983@2157|Archaea,2XXCM@28890|Euryarchaeota,23VW3@183963|Halobacteria	183963|Halobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
DYD1_k127_933621_8	1385515.N791_14755	2.707e-163	522.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1X3X4@135614|Xanthomonadales	135614|Xanthomonadales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD1_k127_933621_63	1459636.NTE_01912	3.155e-48	187.0	COG0159@1|root,arCOG01086@2157|Archaea,41SG0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
DYD1_k127_933621_3	593750.Metfor_2041	2.973e-249	799.0	COG0013@1|root,arCOG01255@2157|Archaea,2XSXB@28890|Euryarchaeota,2N92P@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DYD1_k127_933621_41	797209.ZOD2009_06092	8.062e-79	282.0	COG0577@1|root,arCOG02312@2157|Archaea,2XUEE@28890|Euryarchaeota,23T52@183963|Halobacteria	28890|Euryarchaeota	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DYD1_k127_933621_42	797114.C475_03309	5.501e-74	258.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,23T7A@183963|Halobacteria	183963|Halobacteria	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD1_k127_933621_43	70601.3256500	1.299e-71	260.0	COG2896@1|root,arCOG00930@2157|Archaea,2XT7P@28890|Euryarchaeota,242JX@183968|Thermococci	183968|Thermococci	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
DYD1_k127_933621_98	1094980.Mpsy_1859	3.548e-22	108.0	COG0467@1|root,arCOG01175@2157|Archaea,2Y7UD@28890|Euryarchaeota,2NBDD@224756|Methanomicrobia	224756|Methanomicrobia	T	COG0467 RecA-superfamily ATPases implicated in signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
DYD1_k127_933621_49	1090319.KE386571_gene1915	8.983e-65	234.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,2K03K@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DYD1_k127_933621_59	1487953.JMKF01000028_gene1333	1.045e-50	195.0	COG0451@1|root,COG0451@2|Bacteria,1G2DP@1117|Cyanobacteria,1HA4G@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
DYD1_k127_933621_56	1156937.MFUM_310025	1.33e-53	205.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,46SM2@74201|Verrucomicrobia,37GEE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
DYD1_k127_933621_0	118168.MC7420_4610	6.759e-282	893.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1G092@1117|Cyanobacteria,1H78E@1150|Oscillatoriales	1117|Cyanobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
DYD1_k127_933621_130	1120999.JONM01000012_gene2242	2.317e-06	61.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG2373@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG2373@2|Bacteria,COG4733@2|Bacteria,1QV7E@1224|Proteobacteria,2WHIN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TIGRFAM Outer membrane protein	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
DYD1_k127_933621_28	673860.AciM339_0074	9.172e-105	354.0	COG1236@1|root,arCOG00541@2157|Archaea,2XTIU@28890|Euryarchaeota,3F2F9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Beta-Casp domain	epf1	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
DYD1_k127_933621_23	351160.RCIX2701	1.003e-113	385.0	COG1530@1|root,arCOG00321@2157|Archaea,2XU9U@28890|Euryarchaeota,2N9CZ@224756|Methanomicrobia	224756|Methanomicrobia	L	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DYD1_k127_933621_52	351160.RCIX2700	1.149e-61	235.0	COG0312@1|root,arCOG00322@2157|Archaea,2XV41@28890|Euryarchaeota,2N939@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DYD1_k127_933621_109	406327.Mevan_1560	7.059e-16	88.0	COG0640@1|root,arCOG01686@2157|Archaea,2XYZ4@28890|Euryarchaeota,23R6H@183939|Methanococci	183939|Methanococci	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
DYD1_k127_933621_61	1151117.AJLF01000001_gene721	3.008e-50	186.0	COG0518@1|root,arCOG00087@2157|Archaea,2XT3G@28890|Euryarchaeota,242WF@183968|Thermococci	183968|Thermococci	F	Catalyzes the synthesis of GMP from XMP	guaAA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
DYD1_k127_933621_118	439481.Aboo_1326	1.828e-10	65.0	arCOG05352@1|root,arCOG05352@2157|Archaea,2Y75N@28890|Euryarchaeota,3F3FP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_4	368407.Memar_0730	2.632e-210	662.0	COG5256@1|root,arCOG01561@2157|Archaea,2XTNM@28890|Euryarchaeota,2N9FZ@224756|Methanomicrobia	224756|Methanomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DYD1_k127_933621_60	1054217.TALC_00390	1.512e-50	180.0	COG0051@1|root,arCOG01758@2157|Archaea,2XXV8@28890|Euryarchaeota,241R0@183967|Thermoplasmata	183967|Thermoplasmata	J	Involved in the binding of tRNA to the ribosomes	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DYD1_k127_933621_29	880073.Calab_3350	4.617e-95	328.0	COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
DYD1_k127_933621_48	634498.mru_0924	6.855e-65	236.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,23NK4@183925|Methanobacteria	183925|Methanobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DYD1_k127_933621_100	673860.AciM339_0295	1.383e-21	107.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,3F2N5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	UbiA prenyltransferase family	ubiA	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
DYD1_k127_933621_39	439481.Aboo_0770	2.215e-81	279.0	COG1646@1|root,arCOG01085@2157|Archaea,2XTEC@28890|Euryarchaeota,3F2M3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	pcrB	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
DYD1_k127_933621_44	1455608.JDTH01000002_gene1041	5.641e-68	246.0	COG3407@1|root,arCOG02937@2157|Archaea,2XUJ7@28890|Euryarchaeota,23T1T@183963|Halobacteria	183963|Halobacteria	I	COG3407 Mevalonate pyrophosphate decarboxylase	mvaD	-	4.1.1.99	ko:K17942	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10561	RC00453	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DYD1_k127_933621_13	386456.JQKN01000002_gene2485	1.025e-136	449.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,23NSI@183925|Methanobacteria	183925|Methanobacteria	I	Belongs to the UPF0219 family	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,HMG_CoA_synt_N
DYD1_k127_933621_17	410358.Mlab_1626	4.049e-124	410.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,2N94P@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM Thiolase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
DYD1_k127_933621_70	269797.Mbar_A0549	1.4e-41	161.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,2N9PT@224756|Methanomicrobia	224756|Methanomicrobia	V	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
DYD1_k127_933621_93	716544.wcw_1736	2.319e-26	121.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
DYD1_k127_933621_114	1150864.MILUP08_43693	1.753e-11	76.0	COG0644@1|root,COG0644@2|Bacteria,2GMH9@201174|Actinobacteria,4D8QI@85008|Micromonosporales	201174|Actinobacteria	C	geranylgeranyl reductase	fixC	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,FAD_oxidored,HI0933_like
DYD1_k127_933621_78	443598.AUFA01000013_gene6558	7.149e-39	151.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria,3JYW0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
DYD1_k127_933621_67	1121440.AUMA01000009_gene671	6.926e-43	173.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,42N1Q@68525|delta/epsilon subdivisions,2WJJS@28221|Deltaproteobacteria,2MA1B@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	O-methyltransferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
DYD1_k127_933621_27	316274.Haur_0338	1.669e-105	353.0	COG0604@1|root,COG0604@2|Bacteria,2G9Z7@200795|Chloroflexi,377GH@32061|Chloroflexia	32061|Chloroflexia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
DYD1_k127_933621_77	644966.Tmar_0113	3.983e-39	150.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WCNM@538999|Clostridiales incertae sedis	186801|Clostridia	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DYD1_k127_933621_62	1266909.AUAG01000014_gene2270	2.523e-49	181.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1WY7B@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DYD1_k127_933621_55	1303518.CCALI_00605	2.706e-56	205.0	COG0822@1|root,COG0822@2|Bacteria	2|Bacteria	C	iron-sulfur transferase activity	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DYD1_k127_933621_6	314345.SPV1_11036	8.011e-175	558.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DYD1_k127_933621_34	1123367.C666_03625	2.377e-88	309.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2VMJ9@28216|Betaproteobacteria,2KY6N@206389|Rhodocyclales	206389|Rhodocyclales	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
DYD1_k127_933621_20	472759.Nhal_0689	8.449e-118	385.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
DYD1_k127_933621_2	1183438.GKIL_1930	2.659e-251	782.0	COG0719@1|root,COG0719@2|Bacteria,1G0TH@1117|Cyanobacteria	1117|Cyanobacteria	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DYD1_k127_933621_89	547559.Nmag_4109	1.255e-27	122.0	arCOG02274@1|root,arCOG02274@2157|Archaea,2XVHG@28890|Euryarchaeota,23SZN@183963|Halobacteria	183963|Halobacteria	K	DNA binding protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	HTH_10
DYD1_k127_933621_57	1396418.BATQ01000016_gene4273	1.093e-52	198.0	COG0697@1|root,COG0697@2|Bacteria,46T3I@74201|Verrucomicrobia,2IVMP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD1_k127_933621_73	1202768.JROF01000035_gene2239	4.609e-40	151.0	COG0640@1|root,arCOG01681@2157|Archaea,2XYB2@28890|Euryarchaeota,23WKI@183963|Halobacteria	183963|Halobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD1_k127_933621_88	797299.HALLA_01605	1.229e-28	125.0	COG3832@1|root,arCOG05261@2157|Archaea,2XXIF@28890|Euryarchaeota,23VZ3@183963|Halobacteria	183963|Halobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DYD1_k127_933621_133	1341151.ASZU01000004_gene497	2.136e-05	57.0	COG0477@1|root,COG2814@2|Bacteria,1UI43@1239|Firmicutes,4ISCR@91061|Bacilli,27BDF@186824|Thermoactinomycetaceae	91061|Bacilli	EGP	Major Facilitator Superfamily	yqgE	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
DYD1_k127_933621_83	1394178.AWOO02000043_gene5875	2.059e-30	123.0	COG0640@1|root,COG0640@2|Bacteria,2IQGH@201174|Actinobacteria,4EPUM@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K07721	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
DYD1_k127_933621_32	861299.J421_0447	1.808e-91	311.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DYD1_k127_933621_18	867903.ThesuDRAFT_00419	3.787e-119	398.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WCTC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
DYD1_k127_933621_112	304371.MCP_1199	1.274e-14	87.0	COG3398@1|root,arCOG02611@2157|Archaea,2XYCT@28890|Euryarchaeota,2N9PX@224756|Methanomicrobia	224756|Methanomicrobia	S	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_933621_87	439481.Aboo_0227	9.611e-29	129.0	COG1650@1|root,arCOG01616@2157|Archaea,2XUM0@28890|Euryarchaeota,3F2M2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
DYD1_k127_933621_138	572478.Vdis_0331	5.327e-05	53.0	arCOG04033@1|root,arCOG04033@2157|Archaea,2XR51@28889|Crenarchaeota	28889|Crenarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_125	485914.Hmuk_0622	1.049e-08	68.0	COG3291@1|root,COG3979@1|root,arCOG02546@2157|Archaea,arCOG07581@2157|Archaea,2Y7P8@28890|Euryarchaeota,23S91@183963|Halobacteria	183963|Halobacteria	G	protein contain chitin-binding domain type 3	-	-	-	-	-	-	-	-	-	-	-	-	CBM_5_12,PKD
DYD1_k127_933621_97	1137271.AZUM01000015_gene1665	1.385e-22	114.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DYIP@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DYD1_k127_933621_33	1041930.Mtc_0022	5.641e-90	326.0	COG1293@1|root,arCOG01695@2157|Archaea,2XTMF@28890|Euryarchaeota,2N97T@224756|Methanomicrobia	224756|Methanomicrobia	K	Domain of unknown function (DUF814)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
DYD1_k127_933621_46	1236689.MMALV_05030	1.19e-66	242.0	COG1537@1|root,arCOG01741@2157|Archaea,2XTQ4@28890|Euryarchaeota,3F2P2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_2,eRF1_3
DYD1_k127_933621_129	338963.Pcar_1833	1.425e-06	55.0	COG1145@1|root,COG4624@1|root,COG1145@2|Bacteria,COG4624@2|Bacteria	2|Bacteria	C	iron-sulfur cluster assembly	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_7,PAS,PAS_4,PAS_8
DYD1_k127_933621_16	1054217.TALC_00034	1.995e-124	411.0	COG0519@1|root,arCOG00085@2157|Archaea,2XT82@28890|Euryarchaeota,241KI@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the synthesis of GMP from XMP	guaAB	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GMP_synt_C,NAD_synthase
DYD1_k127_933621_124	1144310.PMI07_005840	8.654e-09	65.0	COG0476@1|root,COG0476@2|Bacteria,1PA3V@1224|Proteobacteria,2VDJV@28211|Alphaproteobacteria,4BBNC@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
DYD1_k127_933621_137	1267535.KB906767_gene4178	4.176e-05	56.0	COG4447@1|root,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
DYD1_k127_933621_102	633149.Bresu_2957	3.92e-19	101.0	COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
DYD1_k127_933621_115	330214.NIDE1891	7.325e-11	76.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Cytochrom_C,DUF1080,DUF4132,Pkinase
DYD1_k127_933621_5	273068.TTE2002	2.911e-187	597.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,42FD3@68295|Thermoanaerobacterales	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
DYD1_k127_933621_75	926569.ANT_10740	1.226e-39	169.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
DYD1_k127_933621_95	439481.Aboo_0313	1.227e-24	115.0	arCOG03142@1|root,arCOG03142@2157|Archaea,2XTSE@28890|Euryarchaeota,3F38F@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_45	1121430.JMLG01000005_gene792	7.083e-67	247.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
DYD1_k127_933621_111	589924.Ferp_0414	8.313e-16	82.0	COG3316@1|root,arCOG02134@2157|Archaea	589924.Ferp_0414|-	L	COG3316 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_74	768672.Desfe_0297	8.634e-40	155.0	COG0794@1|root,arCOG00068@2157|Archaea,2XQ7R@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM sugar isomerase (SIS)	hxlB	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
DYD1_k127_933621_50	439481.Aboo_0637	4.323e-64	241.0	COG0648@1|root,arCOG01894@2157|Archaea,2XU62@28890|Euryarchaeota,3F2J1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
DYD1_k127_933621_30	1192034.CAP_4695	7.462e-95	326.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WM87@28221|Deltaproteobacteria,2YUDN@29|Myxococcales	28221|Deltaproteobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
DYD1_k127_933621_110	1048339.KB913029_gene17	7.687e-16	87.0	2C75R@1|root,2ZCK5@2|Bacteria,2IBVD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_35	105559.Nwat_1587	5.229e-88	317.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1WW1A@135613|Chromatiales	135613|Chromatiales	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
DYD1_k127_933621_68	485913.Krac_0932	1.185e-42	164.0	COG1670@1|root,COG1670@2|Bacteria,2G6X6@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DYD1_k127_933621_40	552811.Dehly_0584	5.479e-81	287.0	COG1208@1|root,COG1208@2|Bacteria,2GAPW@200795|Chloroflexi,34D0H@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
DYD1_k127_933621_7	555079.Toce_1967	1.587e-165	543.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,42EKN@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DYD1_k127_933621_134	935839.JAGJ01000009_gene520	2.639e-05	57.0	COG3291@1|root,COG3507@1|root,COG3525@1|root,COG3291@2|Bacteria,COG3507@2|Bacteria,COG3525@2|Bacteria,2GK90@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Big_2,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,NPCBM_assoc,RicinB_lectin_2
DYD1_k127_933621_85	673860.AciM339_0553	2.418e-29	122.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD1_k127_933621_54	406327.Mevan_0212	5.113e-59	216.0	COG0543@1|root,arCOG02199@2157|Archaea,2XSY9@28890|Euryarchaeota,23QKQ@183939|Methanococci	183939|Methanococci	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DYD1_k127_933621_116	880073.Calab_1273	1.167e-10	74.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	CP_0175	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45,SprT-like
DYD1_k127_933621_99	1347369.CCAD010000087_gene1860	4.966e-22	105.0	COG3339@1|root,COG3339@2|Bacteria,1VC4G@1239|Firmicutes,4IRHA@91061|Bacilli,1ZRUG@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
DYD1_k127_933621_94	1215092.PA6_007_00700	1.296e-25	111.0	COG2105@1|root,COG2105@2|Bacteria,1N3EK@1224|Proteobacteria,1SA6J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
DYD1_k127_933621_131	1343739.PAP_09700	4.257e-06	60.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,2440W@183968|Thermococci	183968|Thermococci	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
DYD1_k127_933621_69	1230457.C476_01202	7.088e-42	170.0	COG0665@1|root,arCOG00755@2157|Archaea,2XT53@28890|Euryarchaeota,23TQC@183963|Halobacteria	183963|Halobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
DYD1_k127_933621_38	292459.STH1727	5.486e-82	286.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
DYD1_k127_933621_25	1070774.J07HN4v3_00637	1.871e-111	388.0	COG0145@1|root,arCOG01511@2157|Archaea,2XT1J@28890|Euryarchaeota,23SV5@183963|Halobacteria	183963|Halobacteria	E	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	hyuA1	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
DYD1_k127_933621_14	1457250.BBMO01000002_gene2921	2.785e-131	440.0	COG0146@1|root,arCOG01512@2157|Archaea,2Y8DU@28890|Euryarchaeota,23S12@183963|Halobacteria	183963|Halobacteria	E	N-methylhydantoinase B acetone carboxylase, alpha subunit	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
DYD1_k127_933621_58	358681.BBR47_21070	1.441e-51	210.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,26R7Y@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	apr	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DYD1_k127_933621_36	1150399.AQYK01000002_gene3209	5.547e-86	319.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
DYD1_k127_933621_105	483219.LILAB_00425	1.06e-17	99.0	COG5640@1|root,COG5640@2|Bacteria,1RIHF@1224|Proteobacteria,42STC@68525|delta/epsilon subdivisions,2WPTD@28221|Deltaproteobacteria,2YU19@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	3.4.21.4	ko:K01312	ko04080,ko04972,ko04974,ko05164,map04080,map04972,map04974,map05164	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	PPC,Trypsin
DYD1_k127_933621_96	1120934.KB894427_gene1038	1.299e-24	112.0	COG2329@1|root,COG2329@2|Bacteria,2IJ23@201174|Actinobacteria,4E5BD@85010|Pseudonocardiales	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
DYD1_k127_933621_81	95619.PM1_0230350	1.982e-33	137.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	enzyme involved in biosynthesis of extracellular polysaccharides	yqjZ	-	-	-	-	-	-	-	-	-	-	-	ABM
DYD1_k127_933621_92	1117318.PRUB_16080	1.508e-26	113.0	2DMP4@1|root,32STA@2|Bacteria,1N1SK@1224|Proteobacteria,1SAHH@1236|Gammaproteobacteria,2Q3KB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_12	1123508.JH636443_gene4754	5.64e-138	451.0	COG0436@1|root,COG0436@2|Bacteria,2IXUY@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DYD1_k127_933621_10	1121346.KB899817_gene3223	1.162e-146	492.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,26QFD@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DYD1_k127_933621_106	1380356.JNIK01000014_gene3184	2.421e-17	96.0	COG2357@1|root,COG4328@1|root,COG2357@2|Bacteria,COG4328@2|Bacteria,2GKF8@201174|Actinobacteria	201174|Actinobacteria	Q	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,RelA_SpoT
DYD1_k127_933621_108	386456.JQKN01000007_gene3253	1.804e-16	82.0	COG2092@1|root,arCOG01988@2157|Archaea,2XYNW@28890|Euryarchaeota,23P7D@183925|Methanobacteria	183925|Methanobacteria	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
DYD1_k127_933621_113	269797.Mbar_A3439	2.309e-13	71.0	COG2888@1|root,arCOG01989@2157|Archaea,2Y736@28890|Euryarchaeota,2NBEG@224756|Methanomicrobia	224756|Methanomicrobia	J	Domain of unknown function (DUF1610)	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	DUF1610
DYD1_k127_933621_86	29540.C481_03037	3.173e-29	121.0	COG1846@1|root,arCOG00732@2157|Archaea,2XZ9E@28890|Euryarchaeota	28890|Euryarchaeota	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
DYD1_k127_933621_119	29540.C481_03032	2.435e-10	71.0	28HS8@1|root,2N5SG@2157|Archaea,2Y3IR@28890|Euryarchaeota,23ZJ6@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_64	1086011.HJ01_03533	5.886e-47	186.0	COG2132@1|root,COG2132@2|Bacteria,4NKG8@976|Bacteroidetes,1I0GF@117743|Flavobacteriia	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
DYD1_k127_933621_71	634497.HAH_1604	4.599e-41	168.0	COG0840@1|root,arCOG02320@2157|Archaea,2XTG0@28890|Euryarchaeota,23SU9@183963|Halobacteria	183963|Halobacteria	N	Methyl-accepting chemotaxis protein	htr8	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
DYD1_k127_933621_47	1446473.JHWH01000001_gene1196	1.475e-66	241.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,2PV6N@265|Paracoccus	28211|Alphaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
DYD1_k127_933621_122	1131266.ARWQ01000006_gene271	9.158e-10	64.0	arCOG03272@1|root,arCOG03272@2157|Archaea,41T3V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_66	1123319.AUBE01000015_gene5674	1.754e-44	182.0	2AQV1@1|root,31G37@2|Bacteria,2IEU1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
DYD1_k127_933621_127	1346330.M472_09490	1.75e-08	65.0	COG1225@1|root,COG1225@2|Bacteria,4P08Q@976|Bacteroidetes	976|Bacteroidetes	O	AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
DYD1_k127_933621_104	1236689.MMALV_01450	3.523e-18	87.0	COG1828@1|root,arCOG04462@2157|Archaea,2Y6YA@28890|Euryarchaeota,3F2VR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
DYD1_k127_933621_1	693661.Arcve_1173	6.075e-260	831.0	COG0046@1|root,arCOG00641@2157|Archaea,2XU49@28890|Euryarchaeota,245S4@183980|Archaeoglobi	183980|Archaeoglobi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DYD1_k127_933621_37	1054217.TALC_00152	1.438e-83	286.0	COG0047@1|root,arCOG00102@2157|Archaea,2XTPA@28890|Euryarchaeota,241Q4@183967|Thermoplasmata	183967|Thermoplasmata	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DYD1_k127_933621_53	1236689.MMALV_00300	1.783e-60	222.0	COG1676@1|root,arCOG01701@2157|Archaea,2XTKB@28890|Euryarchaeota,3F2U2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	tRNA intron endonuclease, catalytic C-terminal domain	endA	GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
DYD1_k127_933621_15	1519464.HY22_08035	8.156e-128	420.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11,4.1.1.45	ko:K00453,ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R00678,R04323	RC00356,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
DYD1_k127_933621_107	768710.DesyoDRAFT_5391	1.794e-16	83.0	2E54P@1|root,32ZXM@2|Bacteria,1W1NZ@1239|Firmicutes,253G2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD1_k127_933621_136	997884.HMPREF1068_01121	3.309e-05	55.0	COG1262@1|root,COG3656@1|root,COG1262@2|Bacteria,COG3656@2|Bacteria,4NGY2@976|Bacteroidetes,2FPTN@200643|Bacteroidia,4AW2R@815|Bacteroidaceae	976|Bacteroidetes	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
DYD1_k127_933621_132	1453505.JASY01000024_gene298	9.277e-06	57.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,1HXSI@117743|Flavobacteriia,2NVDB@237|Flavobacterium	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD1_k127_933621_139	797114.C475_01951	0.00025	53.0	COG1572@1|root,arCOG07561@1|root,arCOG02532@2157|Archaea,arCOG07561@2157|Archaea,2XZY0@28890|Euryarchaeota	28890|Euryarchaeota	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD
DYD1_k127_933621_19	443255.SCLAV_p0535	1.619e-118	402.0	2F3XQ@1|root,33WPT@2|Bacteria	2|Bacteria	S	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
DYD1_k127_933621_84	180281.CPCC7001_1024	6.71e-30	133.0	COG4448@1|root,COG4448@2|Bacteria,1G1X3@1117|Cyanobacteria,22RX7@167375|Cyanobium	1117|Cyanobacteria	E	L-asparaginase II	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_II
DYD1_k127_933621_9	1046627.BZARG_944	8.056e-152	500.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DYD1_k127_933621_123	926690.KE386573_gene1817	1.559e-09	64.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
DYD1_k127_933621_76	309799.DICTH_0131	1.366e-39	160.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
DYD1_k127_933621_26	762376.AXYL_02641	1.94e-107	357.0	COG3384@1|root,COG3384@2|Bacteria,1PUF4@1224|Proteobacteria,2VZW8@28216|Betaproteobacteria,3T6P8@506|Alcaligenaceae	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.74,1.13.11.76	ko:K15059	ko00627,ko01120,map00627,map01120	-	R05405	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
DYD1_k127_933621_91	263358.VAB18032_17820	8.838e-27	118.0	COG3384@1|root,COG3384@2|Bacteria,2H395@201174|Actinobacteria	201174|Actinobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15058	ko00627,ko01120,map00627,map01120	-	R05405	RC00387	ko00000,ko00001	-	-	-	LigB
## 2023 queries scanned
## Total time (seconds): 9.017376184463501
## Rate: 224.34 q/s