## Sun Mar 16 08:15:23 2025 ## emapper-2.1.9 ## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD1_bin.7.fa -m mmseqs --itype genome -o DYD1_bin.7 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD1_bin.7 --cpu 8 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs DYD1_k127_1013589_0 713587.THITH_06130 4.964e-87 295.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1WVY9@135613|Chromatiales 135613|Chromatiales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase DYD1_k127_1013589_1 562970.Btus_1017 5.187e-37 148.0 COG0520@1|root,COG0520@2|Bacteria,1V1F0@1239|Firmicutes,4HIVD@91061|Bacilli,278QS@186823|Alicyclobacillaceae 91061|Bacilli E Aminotransferase class-V - - - ko:K11325 - - - - ko00000 - - - Aminotran_5 DYD1_k127_1026395_0 1123257.AUFV01000008_gene670 1.112e-128 419.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales 135614|Xanthomonadales P Heavy metal translocating P-type atpase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS DYD1_k127_1026395_1 1123073.KB899241_gene2351 2.25e-57 207.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1X510@135614|Xanthomonadales 135614|Xanthomonadales S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin DYD1_k127_1047495_2 4792.ETI39196 1.471e-11 65.0 COG2303@1|root,KOG1238@2759|Eukaryota,3QDG2@4776|Peronosporales 4776|Peronosporales E Belongs to the GMC oxidoreductase family - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N DYD1_k127_1047495_1 1492922.GY26_12970 2.144e-98 338.0 COG2271@1|root,COG2271@2|Bacteria,1QWH9@1224|Proteobacteria,1T3YV@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD1_k127_1047495_0 627192.SLG_20070 3.972e-136 445.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VFM0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD1_k127_1047495_3 314285.KT71_01805 1.829e-09 69.0 2C612@1|root,32RGH@2|Bacteria,1RGYZ@1224|Proteobacteria,1S8MM@1236|Gammaproteobacteria,1J6RN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1053724_0 1442599.JAAN01000013_gene3683 6.068e-119 397.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1X488@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_1053724_1 1452718.JBOY01000066_gene2394 1.397e-102 349.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_1065901_0 1232683.ADIMK_0013 1.27e-321 995.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4645B@72275|Alteromonadaceae 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB DYD1_k127_1065901_1 1283300.ATXB01000002_gene3096 1.299e-135 445.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XE5B@135618|Methylococcales 135618|Methylococcales E PFAM Aminotransferase, class I - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_1065901_2 1380355.JNIJ01000025_gene1187 7.497e-22 99.0 COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,3JRP5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family MA20_37085 - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_1070141_0 396588.Tgr7_1543 1.296e-237 742.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1WVVK@135613|Chromatiales 135613|Chromatiales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 DYD1_k127_1070141_5 545276.KB898726_gene1030 1.033e-42 158.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales 135613|Chromatiales K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD - - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD1_k127_1070141_7 1122604.JONR01000018_gene1085 0.000404 47.0 COG5416@1|root,COG5416@2|Bacteria,1NGPH@1224|Proteobacteria,1SGDB@1236|Gammaproteobacteria,1XBUT@135614|Xanthomonadales 135614|Xanthomonadales S Lipopolysaccharide assembly protein A domain - - - - - - - - - - - - LapA_dom DYD1_k127_1070141_3 1123073.KB899242_gene997 3.201e-68 247.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1X361@135614|Xanthomonadales 135614|Xanthomonadales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_7 DYD1_k127_1070141_6 1118153.MOY_08388 4.185e-15 79.0 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1XMIW@135619|Oceanospirillales 135619|Oceanospirillales L Competence protein ComEA comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 DYD1_k127_1070141_1 243365.CV_3901 6.952e-117 383.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,2KQ12@206351|Neisseriales 206351|Neisseriales M Psort location Cytoplasmic, score 8.96 galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD1_k127_1070141_2 935863.AWZR01000001_gene1904 4.497e-97 321.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria,1X660@135614|Xanthomonadales 135614|Xanthomonadales H Aldolase/RraA - - - - - - - - - - - - RraA-like DYD1_k127_1070141_4 627192.SLG_25140 1.355e-63 230.0 2EVK9@1|root,33P0C@2|Bacteria,1NDYB@1224|Proteobacteria,2UQHZ@28211|Alphaproteobacteria,2K9N4@204457|Sphingomonadales 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1071852_2 1461694.ATO9_09305 2.5e-46 171.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2TSRR@28211|Alphaproteobacteria,2PDCV@252301|Oceanicola 28211|Alphaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus DYD1_k127_1071852_0 1238182.C882_0004 6.973e-140 454.0 COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2TR20@28211|Alphaproteobacteria,2JPF7@204441|Rhodospirillales 204441|Rhodospirillales H ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 DYD1_k127_1071852_1 414684.RC1_2138 3.06e-72 260.0 COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,2TVK6@28211|Alphaproteobacteria,2JRQF@204441|Rhodospirillales 204441|Rhodospirillales E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase DYD1_k127_1077253_0 1122951.ATUE01000006_gene1202 4.724e-133 439.0 COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,1RMS4@1236|Gammaproteobacteria,3NJ8M@468|Moraxellaceae 1236|Gammaproteobacteria M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD1_k127_1077253_2 1082931.KKY_82 6.466e-77 270.0 COG0596@1|root,COG0596@2|Bacteria,1QXD5@1224|Proteobacteria,2UNNR@28211|Alphaproteobacteria,3N93S@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - - DYD1_k127_1077253_1 314285.KT71_11585 3.61e-94 320.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,1J5Q0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S EamA-like transporter family - - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA DYD1_k127_1106453_5 715226.ABI_44880 2.422e-71 244.0 COG1775@1|root,COG1775@2|Bacteria,1R4FZ@1224|Proteobacteria,2U405@28211|Alphaproteobacteria 28211|Alphaproteobacteria E 2-hydroxyglutaryl-CoA dehydratase, D-component - - - - - - - - - - - - HGD-D DYD1_k127_1106453_4 1282360.ABAC460_13110 1.639e-122 402.0 COG1638@1|root,COG1638@2|Bacteria 2|Bacteria G carbohydrate transport - - - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP DYD1_k127_1106453_2 715226.ABI_44900 1.145e-160 524.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2KFBR@204458|Caulobacterales 204458|Caulobacterales C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_1106453_0 234267.Acid_2075 1.159e-195 621.0 COG3356@1|root,COG3356@2|Bacteria,3Y5I7@57723|Acidobacteria 57723|Acidobacteria S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk DYD1_k127_1106453_3 1123487.KB892865_gene1432 5.125e-137 453.0 COG0412@1|root,COG0412@2|Bacteria,1QV1D@1224|Proteobacteria,2WI7G@28216|Betaproteobacteria 28216|Betaproteobacteria Q Tannase and feruloyl esterase - - - - - - - - - - - - Tannase DYD1_k127_1106453_6 313628.LNTAR_09736 2.377e-35 154.0 COG4099@1|root,COG4099@2|Bacteria 2|Bacteria F phospholipase Carboxylesterase - - - - - - - - - - - - Abhydrolase_2,Abhydrolase_8,DLH,Esterase,Peptidase_S9 DYD1_k127_1106453_8 1248916.ANFY01000010_gene335 2.584e-18 90.0 COG2010@1|root,COG2010@2|Bacteria,1NBIA@1224|Proteobacteria,2UHSH@28211|Alphaproteobacteria,2KEUQ@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD1_k127_1106453_1 452662.SJA_C2-00940 4.173e-170 551.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,2K0W1@204457|Sphingomonadales 204457|Sphingomonadales G Glucose dehydrogenase - - 1.1.5.2,1.1.5.8 ko:K00117,ko:K05358 ko00030,ko00400,ko01100,ko01110,ko01130,map00030,map00400,map01100,map01110,map01130 - R01873,R02415,R06620 RC00066,RC00154,RC00206 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 DYD1_k127_1110316_1 756067.MicvaDRAFT_2277 2.845e-23 102.0 COG2890@1|root,COG2890@2|Bacteria,1G6DS@1117|Cyanobacteria,1HE00@1150|Oscillatoriales 1117|Cyanobacteria H PFAM Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_25 DYD1_k127_1110316_0 43989.cce_4306 5.906e-82 287.0 COG0277@1|root,COG0277@2|Bacteria,1GARH@1117|Cyanobacteria 1117|Cyanobacteria C D-arabinono-1,4-lactone oxidase - - - - - - - - - - - - ALO,FAD_binding_4 DYD1_k127_1110761_1 1208321.D104_17980 6.587e-165 526.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XHDH@135619|Oceanospirillales 135619|Oceanospirillales F carbamoyl-phosphate synthetase glutamine chain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase DYD1_k127_1110761_0 765912.Thimo_0297 7.23e-175 552.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales 135613|Chromatiales EF Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS DYD1_k127_1116658_2 1266914.ATUK01000016_gene457 2.188e-14 75.0 2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,1SCQ6@1236|Gammaproteobacteria,1WZ8U@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF3309) - - - - - - - - - - - - DUF3309 DYD1_k127_1116658_0 261292.Nit79A3_1185 1.406e-49 187.0 COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,2VIY9@28216|Betaproteobacteria,372UX@32003|Nitrosomonadales 28216|Betaproteobacteria M Polysaccharide biosynthesis/export protein epsE - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB DYD1_k127_1116658_1 265072.Mfla_2025 4.194e-40 159.0 COG3206@1|root,COG3206@2|Bacteria,1RK0N@1224|Proteobacteria,2VHPS@28216|Betaproteobacteria,2KMI9@206350|Nitrosomonadales 206350|Nitrosomonadales M TIGRFAM chain length determinant protein EpsF - - - - - - - - - - - - GNVR,Wzz DYD1_k127_111760_0 1026882.MAMP_02611 2.587e-158 510.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,45ZNF@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 DYD1_k127_111760_1 754476.Q7A_1538 8.676e-33 129.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,461GC@72273|Thiotrichales 72273|Thiotrichales C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters - - - ko:K04488 - - - - ko00000 - - - NifU_N DYD1_k127_1150416_0 1123392.AQWL01000007_gene1007 2.672e-110 375.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,1KRY7@119069|Hydrogenophilales 119069|Hydrogenophilales S AAA domain - - - - - - - - - - - - AAA_33 DYD1_k127_1150416_1 1209072.ALBT01000045_gene2630 3.443e-27 115.0 2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria,1FHD4@10|Cellvibrio 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1150416_2 388413.ALPR1_12650 8.004e-11 63.0 COG0627@1|root,COG4188@1|root,COG0627@2|Bacteria,COG4188@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia 976|Bacteroidetes E Putative esterase - - - - - - - - - - - - Esterase DYD1_k127_1153600_4 1276756.AUEX01000004_gene2547 5.56e-22 100.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,4AA1T@80864|Comamonadaceae 28216|Betaproteobacteria Q PFAM fumarylacetoacetate (FAA) hydrolase - - - - - - - - - - - - DUF2437,FAA_hydrolase DYD1_k127_1153600_1 1123277.KB893239_gene1214 3.597e-94 320.0 COG0627@1|root,COG0627@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia 976|Bacteroidetes E Putative esterase - - - - - - - - - - - - Esterase DYD1_k127_1153600_2 1116472.MGMO_112c00020 3.124e-51 200.0 COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales 135618|Methylococcales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_1153600_3 234267.Acid_1337 2.201e-50 192.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - ko:K03088 - - - - ko00000,ko03021 - - - Glyoxalase DYD1_k127_1153600_0 1247726.MIM_c02340 2.485e-105 362.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria 28216|Betaproteobacteria G TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2,PQQ_3 DYD1_k127_1159926_2 396595.TK90_0672 2.057e-38 147.0 COG1587@1|root,COG1587@2|Bacteria,1N93T@1224|Proteobacteria,1S367@1236|Gammaproteobacteria,1X0NB@135613|Chromatiales 135613|Chromatiales H Uroporphyrinogen-III synthase HemD - - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 DYD1_k127_1159926_1 980584.AFPB01000138_gene2681 7.635e-40 153.0 COG1017@1|root,COG1017@2|Bacteria,4PK8Z@976|Bacteroidetes,1IEWB@117743|Flavobacteriia,40777@61432|unclassified Flavobacteriaceae 976|Bacteroidetes C Globin - - - - - - - - - - - - Globin DYD1_k127_1159926_0 1461693.ATO10_06961 5.608e-75 255.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2UJF7@28211|Alphaproteobacteria 28211|Alphaproteobacteria NT Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365 DYD1_k127_1165017_2 640511.BC1002_6432 9.461e-11 62.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2W0DK@28216|Betaproteobacteria,1K5G0@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.7.2.3 ko:K07812 - - - - ko00000,ko01000,ko02000 5.A.3.4 - - Molybdopterin,Molydop_binding DYD1_k127_1165017_0 1244869.H261_19918 1.983e-128 417.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TSAP@28211|Alphaproteobacteria,2JRAB@204441|Rhodospirillales 204441|Rhodospirillales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding DYD1_k127_1165017_1 1219080.VEZ01S_36_00130 5.694e-99 328.0 COG0437@1|root,COG0437@2|Bacteria,1R6XQ@1224|Proteobacteria,1TIZA@1236|Gammaproteobacteria,1Y03A@135623|Vibrionales 135623|Vibrionales C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_11 DYD1_k127_1176135_0 314260.PB2503_03077 1.782e-26 123.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS65@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD1_k127_1176135_2 1283299.AUKG01000001_gene3334 7.55e-05 52.0 COG0346@1|root,COG0346@2|Bacteria,2HR7F@201174|Actinobacteria,4CT3D@84995|Rubrobacteria 84995|Rubrobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase_4 DYD1_k127_1176135_1 102129.Lepto7375DRAFT_2537 4.576e-21 94.0 COG3791@1|root,COG3791@2|Bacteria,1G6YI@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA DYD1_k127_1189233_0 377629.TERTU_3619 1.047e-99 342.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,2PP14@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria MU Outer membrane efflux protein opmQ - - - - - - - - - - - OEP DYD1_k127_1189233_1 395493.BegalDRAFT_0760 3.512e-33 137.0 COG1943@1|root,COG1943@2|Bacteria,1P8IT@1224|Proteobacteria,1RSQC@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Sulfotransferase - - - - - - - - - - - - Sulfotransfer_2 DYD1_k127_1195381_4 1177154.Y5S_01714 6.399e-60 216.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,1XQ5M@135619|Oceanospirillales 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 DYD1_k127_1195381_0 443143.GM18_4033 1.597e-315 996.0 COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 DYD1_k127_1195381_7 1232410.KI421425_gene1548 1.267e-38 157.0 COG0457@1|root,COG0457@2|Bacteria,1N1J2@1224|Proteobacteria,42ZHG@68525|delta/epsilon subdivisions,2WV2W@28221|Deltaproteobacteria,43UR6@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - DYD1_k127_1195381_8 1279017.AQYJ01000026_gene63 3.201e-14 76.0 2EQ5T@1|root,33HS3@2|Bacteria,1NMTN@1224|Proteobacteria,1SIGB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1195381_2 1232410.KI421425_gene1546 8.4e-90 301.0 COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria,43TGA@69541|Desulfuromonadales 28221|Deltaproteobacteria U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB DYD1_k127_1195381_5 1232410.KI421425_gene1545 4.391e-51 186.0 COG0848@1|root,COG0848@2|Bacteria,1N8FU@1224|Proteobacteria,42WU3@68525|delta/epsilon subdivisions,2WSMD@28221|Deltaproteobacteria,43UYT@69541|Desulfuromonadales 28221|Deltaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD DYD1_k127_1195381_6 1232410.KI421425_gene1544 4.617e-42 160.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,43V5B@69541|Desulfuromonadales 28221|Deltaproteobacteria U Biopolymer transport protein ExbD/TolR aglS - - - - - - - - - - - ExbD DYD1_k127_1195381_3 1232410.KI421425_gene1543 8.714e-84 295.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,43SUP@69541|Desulfuromonadales 28221|Deltaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C DYD1_k127_1195381_1 1232410.KI421425_gene1554 8.811e-131 424.0 COG1361@1|root,COG1361@2|Bacteria,1R5G4@1224|Proteobacteria,42T0V@68525|delta/epsilon subdivisions,2WPRT@28221|Deltaproteobacteria,43TPS@69541|Desulfuromonadales 28221|Deltaproteobacteria M Domain of unknown function DUF11 - - - - - - - - - - - - DUF11,SdrD_B DYD1_k127_1197518_2 1250232.JQNJ01000001_gene1637 9.133e-58 208.0 COG2367@1|root,COG2367@2|Bacteria,4NHT5@976|Bacteroidetes,1HWY4@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 DYD1_k127_1197518_1 247634.GPB2148_1892 5.012e-69 252.0 COG3202@1|root,COG3202@2|Bacteria,1QXXQ@1224|Proteobacteria,1S2KU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C TLC ATP/ADP transporter - - - - - - - - - - - - TLC DYD1_k127_1197518_0 690850.Desaf_0478 4.942e-111 389.0 COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria,42UE9@68525|delta/epsilon subdivisions,2WR5R@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - - - - - - - - - - PPDK_N DYD1_k127_12167_2 105559.Nwat_2485 1.13e-12 80.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,1X1FR@135613|Chromatiales 135613|Chromatiales M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD1_k127_12167_3 243233.MCA0439 1.638e-08 66.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,1XFS3@135618|Methylococcales 135618|Methylococcales U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - TonB_C DYD1_k127_12167_1 1123256.KB907925_gene1447 1.159e-57 213.0 COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S1WE@1236|Gammaproteobacteria,1X9QR@135614|Xanthomonadales 135614|Xanthomonadales KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_12167_0 1123257.AUFV01000003_gene813 1.084e-81 293.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1X3Y5@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA DYD1_k127_1219646_1 765910.MARPU_00495 1.783e-107 353.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WVYX@135613|Chromatiales 135613|Chromatiales G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase DYD1_k127_1219646_0 375451.RD1_2872 9.62e-202 646.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2TRVS@28211|Alphaproteobacteria,2P1EV@2433|Roseobacter 28211|Alphaproteobacteria G Carbohydrate-binding module 48 (Isoamylase N-terminal domain) glgX - 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 DYD1_k127_1240990_1 1121935.AQXX01000131_gene2883 1.762e-61 213.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1XN9N@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c oxidase subunit III - - - - - - - - - - - - COX3 DYD1_k127_1240990_2 1354722.JQLS01000008_gene3448 2.043e-28 121.0 COG5605@1|root,COG5605@2|Bacteria,1RH8B@1224|Proteobacteria,2U9FI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S small integral membrane protein - - - - - - - - - - - - COX4_pro DYD1_k127_1240990_0 1049564.TevJSym_as00390 8.216e-174 552.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1J4I5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component gtrB - - - - - - - - - - - DctM DYD1_k127_125134_3 1249627.D779_1209 1.647e-30 123.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales 135613|Chromatiales L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD1_k127_125134_2 913325.N799_03955 9.515e-47 175.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales 135614|Xanthomonadales K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 DYD1_k127_125134_0 396588.Tgr7_2146 7.952e-237 742.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales 135613|Chromatiales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C DYD1_k127_125134_1 265072.Mfla_1839 7.83e-129 436.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,2KKPG@206350|Nitrosomonadales 206350|Nitrosomonadales E Domain of unknown function (DUF3488) - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core DYD1_k127_125134_4 754476.Q7A_1227 6.799e-21 94.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S68M@1236|Gammaproteobacteria,463R1@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 DYD1_k127_1252968_3 1121035.AUCH01000021_gene2735 1.47e-14 80.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2VIKH@28216|Betaproteobacteria,2KV3B@206389|Rhodocyclales 206389|Rhodocyclales L DNA polymerase involved in DNA repair - - - ko:K14161 - - - - ko00000,ko03400 - - - IMS DYD1_k127_1252968_2 349124.Hhal_1742 1.538e-46 179.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,1S9RP@1236|Gammaproteobacteria,1WZQP@135613|Chromatiales 135613|Chromatiales D Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K14160 - - - - ko00000,ko03400 - - - SulA DYD1_k127_1252968_0 1120953.AUBH01000005_gene2464 1.102e-75 259.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,4648J@72275|Alteromonadaceae 1236|Gammaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 DYD1_k127_1252968_1 323261.Noc_0717 8.172e-53 192.0 COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1WXGI@135613|Chromatiales 135613|Chromatiales M PFAM ErfK YbiS YcfS YnhG family protein - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - SPOR,YkuD DYD1_k127_1253921_1 395493.BegalDRAFT_1870 4.824e-05 51.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,45ZTT@72273|Thiotrichales 72273|Thiotrichales T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA DYD1_k127_1253921_0 1049564.TevJSym_aq00800 3.626e-149 482.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1J53T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA DYD1_k127_1255803_1 395495.Lcho_0245 4.723e-95 317.0 COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,2VJUF@28216|Betaproteobacteria,1KKAC@119065|unclassified Burkholderiales 28216|Betaproteobacteria S May be involved in the transport of PQQ or its precursor to the periplasm pqqB - - ko:K06136 - - - - ko00000 - - - Lactamase_B_2 DYD1_k127_1255803_0 1286631.X805_00400 1.656e-99 344.0 COG3851@1|root,COG3851@2|Bacteria,1QUAD@1224|Proteobacteria,2WHPU@28216|Betaproteobacteria,1KPMH@119065|unclassified Burkholderiales 28216|Betaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07675 ko02020,map02020 M00473 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 DYD1_k127_1255803_2 1000565.METUNv1_01391 2.356e-70 250.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ32@28216|Betaproteobacteria,2KW7F@206389|Rhodocyclales 206389|Rhodocyclales K helix_turn_helix, Lux Regulon - - - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg DYD1_k127_1255803_3 479434.Sthe_2205 3.229e-63 235.0 COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia 2|Bacteria P Major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_1255803_4 715451.ambt_12015 6.507e-36 141.0 2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,1SGTK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1255803_5 388051.AUFE01000059_gene6145 1.892e-08 62.0 2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2VVSH@28216|Betaproteobacteria,1KAI1@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_127302_1 768066.HELO_4251 2.138e-43 169.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1XJQS@135619|Oceanospirillales 135619|Oceanospirillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_D23 DYD1_k127_127302_2 290398.Csal_2929 6.336e-37 143.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XKEP@135619|Oceanospirillales 135619|Oceanospirillales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar DYD1_k127_127302_3 375286.mma_3107 7.733e-24 106.0 COG3428@1|root,COG3428@2|Bacteria,1NBZS@1224|Proteobacteria,2VYKU@28216|Betaproteobacteria 28216|Betaproteobacteria S Bacterial PH domain - - - - - - - - - - - - bPH_4 DYD1_k127_127302_0 745014.OMB55_00023870 2.254e-76 273.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B DYD1_k127_127302_4 994479.GL877882_gene6739 1.316e-16 87.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity yjhC GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_1281465_1 323261.Noc_1609 1.064e-76 276.0 COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9 DYD1_k127_1281465_0 96561.Dole_0172 6.495e-94 319.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42S0M@68525|delta/epsilon subdivisions,2WNYE@28221|Deltaproteobacteria,2MMEA@213118|Desulfobacterales 28221|Deltaproteobacteria S alpha/beta hydrolase fold yheT - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_1281465_3 391615.ABSJ01000047_gene2121 5.046e-18 91.0 COG1664@1|root,COG1664@2|Bacteria,1MZG6@1224|Proteobacteria 1224|Proteobacteria M Integral membrane protein CcmA involved in cell shape determination WS1240 - - - - - - - - - - - Bactofilin DYD1_k127_1281465_2 1121921.KB898706_gene2292 3.652e-40 155.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,2PN4A@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria H Glutamate-cysteine ligase gshA GO:0003674,GO:0003824,GO:0004357,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042221,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046685,GO:0046689,GO:0046872,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0070887,GO:0071241,GO:0071243,GO:0071248,GO:0071288,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_2885 Glu_cys_ligase DYD1_k127_1285198_5 1049564.TevJSym_bt00040 3.04e-107 350.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1J4D2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Pribosyl_synth,Pribosyltran_N DYD1_k127_1285198_7 396588.Tgr7_0528 2.014e-57 207.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1WYEN@135613|Chromatiales 135613|Chromatiales J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C DYD1_k127_1285198_6 396588.Tgr7_0529 6.862e-63 222.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1WWEP@135613|Chromatiales 135613|Chromatiales J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro DYD1_k127_1285198_1 519989.ECTPHS_02431 1.277e-152 489.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1WWWF@135613|Chromatiales 135613|Chromatiales J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C DYD1_k127_1285198_4 391593.RCCS2_17521 3.006e-108 363.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,2P2C1@2433|Roseobacter 28211|Alphaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_1285198_11 247633.GP2143_18131 3.74e-10 72.0 2C42J@1|root,3359Y@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1285198_10 555793.WSK_4047 1.111e-19 102.0 28NHI@1|root,2ZBJA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1285198_8 1209072.ALBT01000032_gene2123 1.531e-23 107.0 2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_1285198_9 555793.WSK_4047 3.17e-23 110.0 28NHI@1|root,2ZBJA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1285198_2 1448139.AI20_02225 2.074e-133 433.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1Y442@135624|Aeromonadales 135624|Aeromonadales P Belongs to the ABC transporter superfamily - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY DYD1_k127_1285198_3 312309.VF_0691 2.935e-116 382.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,1SMBI@1236|Gammaproteobacteria,1XTVM@135623|Vibrionales 135623|Vibrionales P Belongs to the ABC transporter superfamily dppD - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY DYD1_k127_1285198_0 1123279.ATUS01000001_gene689 2.047e-206 659.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1J5I1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E transport system, periplasmic component - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 DYD1_k127_1286156_2 1255043.TVNIR_2653 2.676e-90 306.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1WWVU@135613|Chromatiales 135613|Chromatiales M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_1286156_4 667632.KB890187_gene3030 2.326e-25 105.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,1KA31@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM Rubredoxin-type Fe(Cys)4 protein rubA - - - - - - - - - - - Rubredoxin DYD1_k127_1286156_3 314278.NB231_13481 1.33e-60 219.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1WXST@135613|Chromatiales 135613|Chromatiales S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA - 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos DYD1_k127_1286156_0 511062.GU3_08355 2.574e-279 872.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1Y3J1@135624|Aeromonadales 135624|Aeromonadales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N DYD1_k127_1286156_5 159450.NH14_07955 2.178e-06 49.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,1K1MS@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD1_k127_1286156_1 626418.bglu_1g05360 4.668e-144 460.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,1K1MS@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD1_k127_1295723_0 550540.Fbal_1400 3.804e-112 367.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases garR - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_1295723_1 381666.H16_B0580 9.982e-81 273.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VZK0@28216|Betaproteobacteria,1K4Q1@119060|Burkholderiaceae 28216|Betaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_1296788_2 313612.L8106_04936 2.786e-79 273.0 COG0500@1|root,COG2230@1|root,COG2226@2|Bacteria,COG2230@2|Bacteria,1G38Q@1117|Cyanobacteria,1HACP@1150|Oscillatoriales 1117|Cyanobacteria H Mycolic acid cyclopropane synthetase sdmt GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052729,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.1.157,2.1.1.161 ko:K13042,ko:K18897 ko00260,map00260 - R07244,R10061 RC00003,RC00496,RC03040 ko00000,ko00001,ko01000 - - - Methyltransf_11 DYD1_k127_1296788_0 631362.Thi970DRAFT_03309 9.633e-139 445.0 COG0500@1|root,COG2226@2|Bacteria,1R5JA@1224|Proteobacteria,1T3U6@1236|Gammaproteobacteria,1X2Q2@135613|Chromatiales 135613|Chromatiales H Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family - - 2.1.1.156 ko:K18896 ko00260,map00260 - R10060 RC00003,RC03038 ko00000,ko00001,ko01000 - - - Methyltransf_25 DYD1_k127_1296788_3 1249627.D779_3015 8.02e-34 136.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1WZMS@135613|Chromatiales 135613|Chromatiales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 DYD1_k127_1296788_1 935840.JAEQ01000020_gene2336 7.529e-128 421.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA DYD1_k127_1297551_1 1049564.TevJSym_ab01320 3.166e-39 153.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 DYD1_k127_1297551_0 32042.PstZobell_04986 5.344e-72 251.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1Z1FE@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA DYD1_k127_1297551_2 157783.LK03_07430 4.345e-18 85.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd DYD1_k127_1299153_1 234267.Acid_5827 1.967e-30 123.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_1299153_0 234267.Acid_2032 4.813e-139 456.0 COG2960@1|root,COG2960@2|Bacteria 2|Bacteria M long-chain fatty acid transporting porin activity - - - - - - - - - - - - HXXSHH DYD1_k127_1299153_2 1282876.BAOK01000001_gene3325 4.554e-06 52.0 COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,2U04Z@28211|Alphaproteobacteria,4BR0Q@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria U Haemolysin secretion/activation protein ShlB/FhaC/HecB hxuB - - - - - - - - - - - POTRA_2,ShlB DYD1_k127_1300885_2 187272.Mlg_1826 3.407e-15 83.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1WW55@135613|Chromatiales 135613|Chromatiales DM peptidase - - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 DYD1_k127_1300885_0 1454004.AW11_00591 2.07e-69 241.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2VT25@28216|Betaproteobacteria,1KQS7@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc DYD1_k127_1300885_1 1286106.MPL1_02583 5.263e-66 230.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,460E3@72273|Thiotrichales 72273|Thiotrichales O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD1_k127_1303853_1 1288826.MSNKSG1_12492 4.012e-82 278.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,465KW@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0155,iYL1228.KPN_03757 Ribul_P_3_epim DYD1_k127_1303853_0 743721.Psesu_1249 6.303e-190 614.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1X4R3@135614|Xanthomonadales 135614|Xanthomonadales E homoserine dehydrogenase thrA - 1.1.1.3,2.7.2.4 ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3 DYD1_k127_1312000_0 1123392.AQWL01000011_gene2260 7.169e-208 653.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VH96@28216|Betaproteobacteria,1KSRX@119069|Hydrogenophilales 119069|Hydrogenophilales Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_3 DYD1_k127_1312000_1 292415.Tbd_1325 7.142e-96 327.0 COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,2VIAG@28216|Betaproteobacteria 28216|Betaproteobacteria P Copper resistance copB2 - - ko:K07233 - - - - ko00000 - - - CopB DYD1_k127_1312000_2 1449355.JQNR01000005_gene2905 1.351e-14 79.0 COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria 201174|Actinobacteria P Copper resistance protein CopC - - - ko:K14166 - - - - ko00000,ko02000 - - - CopC,CopD DYD1_k127_132343_0 414684.RC1_0628 8.739e-295 929.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQPR@204441|Rhodospirillales 204441|Rhodospirillales EQ Hydantoinase/oxoprolinase N-terminal region - - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B DYD1_k127_132343_1 1521187.JPIM01000011_gene2628 2.683e-45 183.0 COG3497@1|root,COG3497@2|Bacteria,2G7YJ@200795|Chloroflexi,37730@32061|Chloroflexia 32061|Chloroflexia S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C DYD1_k127_1334882_0 1049564.TevJSym_ar00230 5.214e-69 251.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1J52S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria MU COG1538 Outer membrane protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP DYD1_k127_1334882_1 396588.Tgr7_0485 1.034e-60 216.0 COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1WX4D@135613|Chromatiales 135613|Chromatiales O PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD1_k127_1334882_2 1123368.AUIS01000023_gene933 2.594e-14 82.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 DYD1_k127_136813_5 1121033.AUCF01000017_gene3774 8.216e-29 129.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2JPVS@204441|Rhodospirillales 204441|Rhodospirillales G Glucose / Sorbosone dehydrogenase - - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH DYD1_k127_136813_3 234267.Acid_1337 2.1e-46 178.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - ko:K03088 - - - - ko00000,ko03021 - - - Glyoxalase DYD1_k127_136813_0 234267.Acid_3334 6.124e-65 235.0 COG3391@1|root,COG3391@2|Bacteria,3Y3R3@57723|Acidobacteria 57723|Acidobacteria S TIGRFAM 40-residue YVTN family beta-propeller repeat - - - - - - - - - - - - Lactonase DYD1_k127_136813_6 937777.Deipe_2859 3.367e-08 59.0 COG1555@1|root,COG4454@1|root,COG1555@2|Bacteria,COG4454@2|Bacteria 2|Bacteria L photosystem II stabilization comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Cu_amine_oxidN1,DUF4157,HHH_3,SLBB,SoxE DYD1_k127_136813_2 1472418.BBJC01000004_gene1788 1.065e-49 193.0 2CBAE@1|root,31814@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_136813_4 1280948.HY36_07015 9.904e-39 151.0 2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,2U9KI@28211|Alphaproteobacteria,43Y10@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD1_k127_136813_1 1280950.HJO_08182 1.116e-55 200.0 COG1917@1|root,COG1917@2|Bacteria,1RHWW@1224|Proteobacteria,2U9UU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 DYD1_k127_136813_7 290317.Cpha266_0806 3.487e-05 47.0 COG0679@1|root,COG0679@2|Bacteria 2|Bacteria S auxin-activated signaling pathway - - - ko:K07088 - - - - ko00000 - - - Mem_trans DYD1_k127_140528_1 371731.Rsw2DRAFT_1814 7.086e-83 290.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,1FBM4@1060|Rhodobacter 28211|Alphaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE DYD1_k127_140528_0 1123247.AUIJ01000001_gene1779 1.744e-85 288.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type molybdate transport system, permease component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 DYD1_k127_140528_2 1097668.BYI23_A023350 5.874e-67 232.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,1K1WK@119060|Burkholderiaceae 28216|Betaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein DYD1_k127_140528_3 1121921.KB898706_gene2722 1.016e-42 163.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2PNZB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria NU Pilin (bacterial filament) pilA - - ko:K02650,ko:K02655 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD1_k127_1417100_1 314230.DSM3645_29316 1.282e-111 366.0 COG3588@1|root,COG3588@2|Bacteria 2|Bacteria G fructose-bisphosphate aldolase fda - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic DYD1_k127_1417100_2 1121129.KB903359_gene1748 4.534e-63 225.0 COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,2FSAZ@200643|Bacteroidia,22Z2D@171551|Porphyromonadaceae 976|Bacteroidetes S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE DYD1_k127_1417100_0 999547.KI421502_gene3768 8.712e-210 662.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the glutamate synthase family - - - - - - - - - - - - Glu_synthase DYD1_k127_1417100_3 1227739.Hsw_1325 6.823e-38 155.0 COG3391@1|root,COG3391@2|Bacteria,4NIYC@976|Bacteroidetes,47YG2@768503|Cytophagia 976|Bacteroidetes S amine dehydrogenase activity - - - - - - - - - - - - SGL DYD1_k127_1428627_0 288000.BBta_7794 1.823e-272 851.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2U0IK@28211|Alphaproteobacteria,3JTMI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD1_k127_1428627_1 589873.EP13_17080 6.35e-53 193.0 COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,4669S@72275|Alteromonadaceae 1236|Gammaproteobacteria U UPF0056 membrane protein yhgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD1_k127_1428627_2 1209072.ALBT01000058_gene915 1.251e-34 136.0 COG0834@1|root,COG2199@1|root,COG2200@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1R6FI@1224|Proteobacteria,1S1V8@1236|Gammaproteobacteria,1FHUQ@10|Cellvibrio 1236|Gammaproteobacteria ET Bacterial periplasmic substrate-binding proteins - - - - - - - - - - - - EAL,GGDEF,SBP_bac_3 DYD1_k127_1432052_1 91464.S7335_1999 7.715e-38 154.0 COG2199@1|root,COG2199@2|Bacteria,1GHDT@1117|Cyanobacteria,1H4E6@1129|Synechococcus 1117|Cyanobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS,PAS_4,Response_reg DYD1_k127_1432052_0 1042377.AFPJ01000043_gene898 4.819e-83 293.0 2A6A4@1|root,30V2R@2|Bacteria,1RENE@1224|Proteobacteria,1SNHE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1449672_1 1163408.UU9_16426 2.256e-36 140.0 COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - Rhomboid DYD1_k127_1449672_4 1122134.KB893650_gene1679 8.388e-12 76.0 COG3658@1|root,COG3658@2|Bacteria,1N6Y9@1224|Proteobacteria,1SCBR@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PgaD-like protein - - - ko:K11937 ko02026,map02026 - - - ko00000,ko00001 - - - PgaD DYD1_k127_1449672_0 1122134.KB893650_gene1680 2.736e-116 378.0 COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,1RMS4@1236|Gammaproteobacteria,1XIIB@135619|Oceanospirillales 135619|Oceanospirillales M Glycosyl transferase family 21 - - - ko:K11936 ko02026,map02026 - - - ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.2,4.D.1.1.3 GT2 - Glyco_tranf_2_3 DYD1_k127_1454663_2 269796.Rru_A1906 6.828e-111 370.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2TUH6@28211|Alphaproteobacteria,2JQNI@204441|Rhodospirillales 1224|Proteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) bicA - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp,cNMP_binding DYD1_k127_1454663_1 1183438.GKIL_2152 9.656e-115 388.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - - - - - - - - - - Amidohydro_1 DYD1_k127_1454663_0 1183438.GKIL_2151 1.523e-143 468.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1,Amidohydro_3 DYD1_k127_1457431_0 234267.Acid_0751 2.051e-232 743.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - FtsX,MacB_PCD DYD1_k127_1470604_0 886293.Sinac_1154 1.183e-62 221.0 COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_1470604_1 886293.Sinac_1155 2.719e-51 199.0 COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes 203682|Planctomycetes S Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_4 DYD1_k127_1479178_0 558884.JRGM01000130_gene176 6.503e-88 298.0 COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1Y3GJ@135624|Aeromonadales 135624|Aeromonadales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K06879 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF,QueF_N DYD1_k127_1479178_2 425104.Ssed_0636 5.142e-20 96.0 2EICS@1|root,33C43@2|Bacteria,1NIAI@1224|Proteobacteria,1SGPY@1236|Gammaproteobacteria,2QCPZ@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1479178_1 247639.MGP2080_01361 2.973e-22 97.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1J591@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 DYD1_k127_1489592_1 395493.BegalDRAFT_3451 1.2e-71 254.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,460F4@72273|Thiotrichales 72273|Thiotrichales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 DYD1_k127_1489592_0 187272.Mlg_0596 4.386e-162 522.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1WVW6@135613|Chromatiales 135613|Chromatiales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 DYD1_k127_14926_1 566466.NOR53_398 7.842e-74 257.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,1J55S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PEGA DYD1_k127_14926_0 1415778.JQMM01000001_gene1138 9.51e-98 325.0 COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria,1J4YC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins - - - - - - - - - - - - MotA_ExbB DYD1_k127_14926_2 1415778.JQMM01000001_gene1137 1.049e-38 161.0 2ASXF@1|root,31ID0@2|Bacteria,1RM30@1224|Proteobacteria,1S8I2@1236|Gammaproteobacteria,1JAB6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1516162_0 247634.GPB2148_3272 6.259e-70 253.0 COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - - - - - - - - - - Metallophos DYD1_k127_1516162_1 291985.CCSI01000007_gene460 3.577e-50 193.0 28M5H@1|root,2ZAJ9@2|Bacteria,1RJY2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_1516162_3 1177181.T9A_00179 2.079e-06 57.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XIQI@135619|Oceanospirillales 135619|Oceanospirillales C Cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,UnbV_ASPIC,VCBS DYD1_k127_1520618_1 247633.GP2143_17796 6.665e-30 136.0 28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1520618_0 1122604.JONR01000039_gene3751 1.296e-87 298.0 COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,1SBI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_1520618_2 1484157.PSNIH2_00290 9.621e-12 72.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,3VXTH@53335|Pantoea 1236|Gammaproteobacteria G Quinoprotein glucose dehydrogenase gcd GO:0000287,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005575,GO:0008150,GO:0008152,GO:0008876,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0031224,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044425,GO:0046872,GO:0048037,GO:0048038,GO:0048039,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2,1.1.5.8 ko:K00117,ko:K05358 ko00030,ko00400,ko01100,ko01110,ko01130,map00030,map00400,map01100,map01110,map01130 - R01873,R02415,R06620 RC00066,RC00154,RC00206 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_0117,iECIAI1_1343.ECIAI1_0122,iECW_1372.ECW_m0121,iEKO11_1354.EKO11_3792,iWFL_1372.ECW_m0121 PQQ DYD1_k127_152598_0 697282.Mettu_2804 2.869e-85 287.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1XE4R@135618|Methylococcales 135618|Methylococcales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM DYD1_k127_152598_2 247634.GPB2148_2608 1.49e-42 168.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria 1224|Proteobacteria L Hydrolase nudF - - - - - - - - - - - NUDIX DYD1_k127_152598_1 530564.Psta_2393 7.676e-66 232.0 COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes 203682|Planctomycetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate DYD1_k127_1539073_0 926550.CLDAP_36930 2.399e-81 282.0 COG0477@1|root,COG0477@2|Bacteria,2GA8P@200795|Chloroflexi 200795|Chloroflexi EGP Major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1,Sugar_tr DYD1_k127_1539073_1 318161.Sden_0639 8.557e-41 157.0 COG4659@1|root,COG4659@2|Bacteria,1MZVX@1224|Proteobacteria,1S9KJ@1236|Gammaproteobacteria,2QBRU@267890|Shewanellaceae 1236|Gammaproteobacteria C FMN-binding domain protein - - - - - - - - - - - - FMN_bind DYD1_k127_1551273_1 472759.Nhal_3354 8.074e-43 160.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1WXMI@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_3,HlyD_D23 DYD1_k127_1551273_0 349521.HCH_01263 7.436e-82 281.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1XI1E@135619|Oceanospirillales 135619|Oceanospirillales V Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003,ko:K09810 ko02010,map02010 M00255,M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.125 - - ABC_tran DYD1_k127_1551273_2 472759.Nhal_3356 7.193e-33 133.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1WXP0@135613|Chromatiales 135613|Chromatiales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_1597678_2 234267.Acid_4087 2.137e-28 125.0 COG5549@1|root,COG5549@2|Bacteria 2|Bacteria O protein import - - - - - - - - - - - - Ank_4,Peptidase_M10 DYD1_k127_1597678_0 614083.AWQR01000022_gene106 2.041e-133 435.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2VP80@28216|Betaproteobacteria,4ADEX@80864|Comamonadaceae 28216|Betaproteobacteria S Amidohydrolase - - 4.1.1.103,4.1.1.46 ko:K07045,ko:K14333,ko:K20941 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R11353 RC00390,RC00569 ko00000,ko00001,ko01000 - - - Amidohydro_2 DYD1_k127_1597678_3 1298867.AUES01000007_gene4947 6.572e-27 117.0 COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2U65K@28211|Alphaproteobacteria,3JY8W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_1597678_1 1038860.AXAP01000021_gene5518 1.516e-101 338.0 COG2084@1|root,COG2084@2|Bacteria,1MWR4@1224|Proteobacteria,2U157@28211|Alphaproteobacteria,3JRTW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MA20_14105 - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_1603356_0 234267.Acid_2664 3.969e-238 749.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2 DYD1_k127_1616799_2 314287.GB2207_11573 8.176e-85 292.0 COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,1RSKQ@1236|Gammaproteobacteria,1J6EV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G COG3386 Gluconolactonase - - 3.1.1.15 ko:K13874 ko00053,ko01100,map00053,map01100 - R02526 RC00537 ko00000,ko00001,ko01000 - - - SGL DYD1_k127_1616799_0 1250232.JQNJ01000001_gene1905 2.165e-140 454.0 COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia 976|Bacteroidetes S Sodium bile acid symporter family - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF DYD1_k127_1616799_4 1340493.JNIF01000004_gene47 0.0002033 46.0 COG4948@1|root,COG4948@2|Bacteria 2|Bacteria M carboxylic acid catabolic process - - 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N DYD1_k127_1616799_1 1254432.SCE1572_33250 1e-136 449.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,42QV3@68525|delta/epsilon subdivisions,2WMT2@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH DYD1_k127_1616799_3 1346791.M529_14365 6.157e-35 138.0 COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,2TTJ7@28211|Alphaproteobacteria,2K0YY@204457|Sphingomonadales 204457|Sphingomonadales G Converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim DYD1_k127_1619807_1 883078.HMPREF9695_03783 1.115e-70 248.0 COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2TV0G@28211|Alphaproteobacteria,3K6XF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_7 DYD1_k127_1619807_0 640081.Dsui_3260 8.075e-226 707.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales 206389|Rhodocyclales C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase DYD1_k127_1620607_2 644968.DFW101_0020 6.173e-26 111.0 2AHM7@1|root,317Z3@2|Bacteria,1PZHH@1224|Proteobacteria,435Z7@68525|delta/epsilon subdivisions,2X0GI@28221|Deltaproteobacteria,2MC94@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1620607_1 941449.dsx2_3131 5.243e-45 171.0 COG2864@1|root,COG2864@2|Bacteria 2|Bacteria C formate dehydrogenase - - - - - - - - - - - - Ni_hydr_CYTB DYD1_k127_1620607_0 644968.DFW101_0022 1.022e-59 211.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2M9BS@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM Molybdopterin dehydrogenase, FAD-binding - - 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_1626781_3 1286093.C266_25885 7.404e-45 173.0 2DRCH@1|root,33B7I@2|Bacteria,1NN9U@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_1626781_1 290398.Csal_3292 1.517e-61 222.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1XHMA@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc DYD1_k127_1626781_4 1173024.KI912152_gene817 3.108e-39 149.0 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - HTH_20 DYD1_k127_1626781_0 1173024.KI912152_gene818 1.468e-71 250.0 COG3832@1|root,COG3832@2|Bacteria,1GRIT@1117|Cyanobacteria,1JMJW@1189|Stigonemataceae 1117|Cyanobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD1_k127_1626781_5 269798.CHU_1110 1.128e-38 153.0 COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes 976|Bacteroidetes S Pfam Activator of Hsp90 ATPase - - - - - - - - - - - - AHSA1 DYD1_k127_1626781_2 1207063.P24_01480 8.18e-47 175.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2TSQ2@28211|Alphaproteobacteria,2JRD2@204441|Rhodospirillales 204441|Rhodospirillales P protein involved in response to NO - - - ko:K07234 - - - - ko00000 - - - NnrS DYD1_k127_164159_1 1042876.PPS_1377 5.801e-68 242.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1YXE0@136845|Pseudomonas putida group 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 ko:K02517,ko:K12974 ko00540,ko01100,map00540,map01100 M00060 R05146,R10906 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068 Lip_A_acyltrans DYD1_k127_164159_2 234267.Acid_4171 2.543e-47 181.0 COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria 57723|Acidobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_164159_0 1298867.AUES01000001_gene1913 1.087e-74 265.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,3JV8N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471 DYD1_k127_164159_3 1415780.JPOG01000001_gene392 4.131e-23 108.0 COG2353@1|root,COG2353@2|Bacteria,1N3P9@1224|Proteobacteria,1SDBE@1236|Gammaproteobacteria,1XAHR@135614|Xanthomonadales 135614|Xanthomonadales S YceI-like domain - - - - - - - - - - - - YceI DYD1_k127_1642950_2 1280941.HY2_13050 6.103e-28 121.0 COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,43XXP@69657|Hyphomonadaceae 28211|Alphaproteobacteria C COG3474 Cytochrome c2 - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944 - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C DYD1_k127_1642950_1 550540.Fbal_3128 1.391e-42 163.0 COG2930@1|root,COG2930@2|Bacteria,1RCYH@1224|Proteobacteria,1S41U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Las17-binding protein actin regulator CT2216 - - - - - - - - - - - Ysc84 DYD1_k127_1642950_0 1123059.KB823013_gene560 2.025e-62 217.0 COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,2TU91@28211|Alphaproteobacteria,43W6R@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_1643429_1 1209072.ALBT01000009_gene3047 5.886e-46 178.0 COG4972@1|root,COG4972@2|Bacteria,1N0HS@1224|Proteobacteria,1SAQC@1236|Gammaproteobacteria,1FGVG@10|Cellvibrio 1236|Gammaproteobacteria NU Pilus assembly protein mshI - - ko:K12279 - - - - ko00000,ko02044 - - - - DYD1_k127_1643429_0 591159.ACEZ01000052_gene3197 3.842e-96 326.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria 201174|Actinobacteria EQ PFAM Hydantoinase oxoprolinase oplA - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - iNJ661.Rv0266c Hydant_A_N,Hydantoinase_A,Hydantoinase_B DYD1_k127_1654510_2 472759.Nhal_0475 6.467e-53 204.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales 135613|Chromatiales M PFAM LppC - - - ko:K07121 - - - - ko00000 - - - LppC DYD1_k127_1654510_4 1177181.T9A_02035 2.539e-23 108.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1XM4S@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 DYD1_k127_1654510_1 870187.Thini_3135 9.717e-69 238.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,460NU@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 DYD1_k127_1654510_3 713586.KB900536_gene1392 8.425e-30 123.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1WYWV@135613|Chromatiales 135613|Chromatiales S Stringent starvation protein B - - - ko:K03600 - - - - ko00000,ko03021 - - - SspB DYD1_k127_1654510_0 998674.ATTE01000001_gene2444 1.601e-78 267.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,460HZ@72273|Thiotrichales 72273|Thiotrichales O Stringent starvation protein A - - - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_N_3 DYD1_k127_1654510_5 1268239.PALB_12310 1.342e-20 93.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,2PZW1@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P cytochrome c1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 DYD1_k127_1655397_0 1120953.AUBH01000001_gene914 3.203e-122 404.0 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,46698@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_1655397_1 1535422.ND16A_3225 5.388e-71 245.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,2Q64A@267889|Colwelliaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_165951_2 765911.Thivi_4260 1.657e-25 116.0 COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,1WWAJ@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c DYD1_k127_165951_0 243233.MCA2487 4.167e-216 680.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,1XE5W@135618|Methylococcales 135618|Methylococcales C Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_165951_1 935557.ATYB01000008_gene5076 2.68e-52 188.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2TQPI@28211|Alphaproteobacteria,4BB7T@82115|Rhizobiaceae 28211|Alphaproteobacteria M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD1_k127_1662506_0 1121939.L861_10510 4.016e-136 441.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RP9W@1236|Gammaproteobacteria,1XIFB@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - - - - - - - - - - DJ-1_PfpI,HTH_18 DYD1_k127_1662506_1 1217720.ALOX01000034_gene336 8.056e-133 441.0 COG1506@1|root,COG1506@2|Bacteria,1R968@1224|Proteobacteria,2TXT1@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Tannase and feruloyl esterase - - - - - - - - - - - - Tannase DYD1_k127_1662506_2 1283299.AUKG01000003_gene666 1.234e-57 207.0 COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria 201174|Actinobacteria C Belongs to the iron ascorbate-dependent oxidoreductase family efe - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N DYD1_k127_167186_2 1242864.D187_007141 1.049e-05 50.0 COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,2YUR4@29|Myxococcales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_167186_0 1168034.FH5T_10400 5.489e-168 565.0 COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes,2FM1V@200643|Bacteroidia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran DYD1_k127_167186_1 28229.ND2E_1345 1.372e-19 96.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q6IX@267889|Colwelliaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran DYD1_k127_1673846_0 518766.Rmar_1743 6.834e-72 248.0 COG1082@1|root,COG1082@2|Bacteria,4NG1K@976|Bacteroidetes 976|Bacteroidetes G Xylose isomerase - - - - - - - - - - - - AP_endonuc_2 DYD1_k127_1673846_1 886293.Sinac_1155 1.085e-61 222.0 COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes 203682|Planctomycetes S Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_4 DYD1_k127_1685230_0 1121123.AUAO01000003_gene2316 2.24e-63 227.0 COG4322@1|root,COG4322@2|Bacteria,1R4WQ@1224|Proteobacteria,2UJVW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2272) - - - - - - - - - - - - DUF2272 DYD1_k127_1685230_1 1026882.MAMP_01020 4.356e-17 95.0 COG3471@1|root,COG3471@2|Bacteria,1MZA2@1224|Proteobacteria,1S793@1236|Gammaproteobacteria,4615M@72273|Thiotrichales 72273|Thiotrichales S periplasmic secreted protein - - - - - - - - - - - - SIMPL DYD1_k127_1685820_0 765913.ThidrDRAFT_4164 1.007e-110 361.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1WVYR@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N DYD1_k127_1685820_3 1278309.KB907100_gene2307 1.147e-33 136.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1XK2G@135619|Oceanospirillales 135619|Oceanospirillales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP DYD1_k127_1685820_2 1051646.VITU9109_19944 4.011e-39 151.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1XVBF@135623|Vibrionales 135623|Vibrionales C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B DYD1_k127_1685820_4 349521.HCH_07077 2.031e-26 110.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1XKRQ@135619|Oceanospirillales 135619|Oceanospirillales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C DYD1_k127_1685820_1 1027273.GZ77_21965 2.939e-80 272.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XH68@135619|Oceanospirillales 135619|Oceanospirillales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A DYD1_k127_1700787_3 395493.BegalDRAFT_2993 7.862e-32 126.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,4605T@72273|Thiotrichales 72273|Thiotrichales O molecular chaperone - - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C DYD1_k127_1700787_0 666509.RCA23_c24890 7.178e-141 469.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8 DYD1_k127_1700787_1 1298858.AUEL01000018_gene2870 1.358e-60 216.0 COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2U0PQ@28211|Alphaproteobacteria,43K1B@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 DYD1_k127_1700787_2 1500257.JQNM01000001_gene3722 8.191e-41 158.0 COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria,4BA8I@82115|Rhizobiaceae 28211|Alphaproteobacteria S Predicted metal-binding integral membrane protein (DUF2182) - - - - - - - - - - - - DUF2182 DYD1_k127_1702224_5 713587.THITH_02925 0.0004035 45.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales 135613|Chromatiales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N DYD1_k127_1702224_4 1123257.AUFV01000002_gene2634 2.007e-06 59.0 COG3064@1|root,COG3064@2|Bacteria,1NDEI@1224|Proteobacteria,1T2B3@1236|Gammaproteobacteria,1X89R@135614|Xanthomonadales 135614|Xanthomonadales M TonB C terminal - - - - - - - - - - - - TonB_2 DYD1_k127_1702224_2 323261.Noc_0143 4.525e-33 142.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1WY2R@135613|Chromatiales 135613|Chromatiales U PFAM Biopolymer transport protein ExbD TolR - - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD DYD1_k127_1702224_0 765911.Thivi_1795 1.449e-70 245.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1WWA0@135613|Chromatiales 135613|Chromatiales U PFAM MotA TolQ ExbB proton channel - - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB DYD1_k127_1702224_3 1123367.C666_05145 3.887e-24 106.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,2KWWA@206389|Rhodocyclales 206389|Rhodocyclales S Tol-pal system-associated acyl-CoA thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT DYD1_k127_1702224_1 312153.Pnuc_1880 4.033e-34 132.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,1K2TQ@119060|Burkholderiaceae 28216|Betaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N DYD1_k127_1703799_0 391615.ABSJ01000026_gene133 1.433e-19 99.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J4C2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_1703799_2 234267.Acid_2032 2.358e-11 67.0 COG2960@1|root,COG2960@2|Bacteria 2|Bacteria M long-chain fatty acid transporting porin activity - - - - - - - - - - - - HXXSHH DYD1_k127_172171_0 713586.KB900536_gene3089 4.397e-231 724.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1WXCW@135613|Chromatiales 135613|Chromatiales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH DYD1_k127_172171_1 713586.KB900536_gene3088 8.383e-72 249.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales 135613|Chromatiales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 DYD1_k127_1771167_3 297246.lpp0630 2.672e-22 100.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1JC7X@118969|Legionellales 118969|Legionellales C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim DYD1_k127_1771167_0 472759.Nhal_0455 7.458e-207 663.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1WW1J@135613|Chromatiales 135613|Chromatiales E PFAM peptidase M3A and M3B, thimet oligopeptidase F - - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 DYD1_k127_1771167_1 396588.Tgr7_0007 3.712e-103 341.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1WWV1@135613|Chromatiales 135613|Chromatiales L PFAM Endonuclease Exonuclease phosphatase - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos DYD1_k127_1771167_2 1123257.AUFV01000012_gene2925 1.027e-52 192.0 2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1X5H4@135614|Xanthomonadales 135614|Xanthomonadales S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - - DYD1_k127_1786417_1 1267535.KB906767_gene3668 1.028e-25 115.0 COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria 57723|Acidobacteria KT Peptidase M56, BlaR1 - - - - - - - - - - - - DUF3738,Peptidase_M56 DYD1_k127_1786417_0 682795.AciX8_2515 7.639e-43 162.0 COG3682@1|root,COG3682@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - Penicillinase_R DYD1_k127_1802693_0 1121904.ARBP01000021_gene3619 2.28e-188 601.0 COG1629@1|root,COG4771@2|Bacteria,4PMSN@976|Bacteroidetes 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,OMP_b-brl_3,Plug DYD1_k127_1802693_1 87626.PTD2_05830 8.347e-14 80.0 COG1396@1|root,COG1396@2|Bacteria,1RG5J@1224|Proteobacteria,1S5PT@1236|Gammaproteobacteria,2Q2WB@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 DYD1_k127_1822439_1 1316936.K678_02468 4.677e-75 258.0 COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2JPM6@204441|Rhodospirillales 204441|Rhodospirillales S nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - - - - - - - - - - MoCF_biosynth DYD1_k127_1822439_0 396588.Tgr7_0061 8.657e-123 402.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales 135613|Chromatiales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 DYD1_k127_1838343_0 319003.Bra1253DRAFT_03937 1.629e-66 232.0 COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,2U06R@28211|Alphaproteobacteria,3JRXQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx DYD1_k127_1838343_2 1088721.NSU_2823 3.441e-17 93.0 28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2U8EJ@28211|Alphaproteobacteria,2KCBM@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_1838343_1 555793.WSK_2000 9.738e-18 89.0 2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_1838562_3 472759.Nhal_3934 3.649e-26 121.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,1WZTH@135613|Chromatiales 135613|Chromatiales H HemX, putative uroporphyrinogen-III C-methyltransferase - - 2.1.1.107 ko:K02496 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - HemX DYD1_k127_1838562_2 396588.Tgr7_0031 6.427e-70 244.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1WY8N@135613|Chromatiales 135613|Chromatiales KT Response regulator of the LytR AlgR family - - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg DYD1_k127_1838562_1 1177154.Y5S_03157 8.469e-78 273.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1XJDR@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein with a C-terminal ATPase domain algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase DYD1_k127_1838562_5 1395571.TMS3_0118745 1.482e-05 56.0 2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 DYD1_k127_1838562_4 1158146.KB907121_gene1069 6.835e-21 94.0 COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,1WYUC@135613|Chromatiales 135613|Chromatiales S Membrane fusogenic activity - - - ko:K09806 - - - - ko00000 - - - BMFP DYD1_k127_1838562_0 1301098.PKB_5628 1.634e-146 480.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria 1236|Gammaproteobacteria O ATPase with chaperone activity comM GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C DYD1_k127_1839474_5 391615.ABSJ01000037_gene913 5.233e-21 98.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1J67X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520 PgpA DYD1_k127_1839474_1 1485544.JQKP01000019_gene33 1.74e-78 275.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,44VFP@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD1_k127_1839474_4 598467.BrE312_3387 1.754e-28 120.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB DYD1_k127_1839474_2 754476.Q7A_977 5.356e-52 189.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,460J0@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase DYD1_k127_1839474_0 472759.Nhal_2813 9.386e-138 445.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1WW6K@135613|Chromatiales 135613|Chromatiales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 DYD1_k127_1839474_6 1220551.SCHR_05547 0.0001959 44.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,4GXFT@90964|Staphylococcaceae 91061|Bacilli H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 DYD1_k127_1839474_3 767434.Fraau_0451 1.656e-46 172.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1X4H0@135614|Xanthomonadales 135614|Xanthomonadales H Riboflavin synthase ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding DYD1_k127_1849087_0 1048983.EL17_16160 2.287e-109 365.0 COG0402@1|root,COG0402@2|Bacteria,4PAS2@976|Bacteroidetes,47W68@768503|Cytophagia 976|Bacteroidetes F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD1_k127_1852862_2 1304275.C41B8_14450 1.522e-59 218.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - iJN746.PP_4169,iSFV_1184.SFV_3923 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N DYD1_k127_1852862_6 857087.Metme_0271 1.506e-42 163.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1XEZ2@135618|Methylococcales 135618|Methylococcales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB DYD1_k127_1852862_9 93220.LV28_16780 4.617e-22 100.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,1K7Q4@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM Rhodanese domain protein glpE - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD1_k127_1852862_3 1049564.TevJSym_at00270 6.549e-59 218.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1J4S5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D COG4942 Membrane-bound metallopeptidase envC GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - - - - - - - - - - Peptidase_M23 DYD1_k127_1852862_1 1249627.D779_0871 1.555e-100 342.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1WVW7@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 DYD1_k127_1852862_5 713587.THITH_15175 1.923e-52 200.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1T54V@1236|Gammaproteobacteria,1X2UH@135613|Chromatiales 135613|Chromatiales T diguanylate cyclase - - - - - - - - - - - - GGDEF DYD1_k127_1852862_11 861299.J421_0657 1.194e-05 57.0 29Y7Z@1|root,30K1P@2|Bacteria,1ZVAK@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - DYD1_k127_1852862_12 384676.PSEEN0987 0.0002412 49.0 2DQH6@1|root,336TK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1852862_8 1244531.CIG1485E_1270 1.519e-28 116.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2YQAF@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S RNA-binding protein rbpA - - - - - - - - - - - RRM_1 DYD1_k127_1852862_4 1128421.JAGA01000002_gene1306 4.202e-53 191.0 COG2050@1|root,COG2050@2|Bacteria 2|Bacteria Q thiolester hydrolase activity - - - - - - - - - - - - 4HBT DYD1_k127_1852862_0 247639.MGP2080_04535 2.772e-101 336.0 28HGK@1|root,2Z7SE@2|Bacteria,1R43R@1224|Proteobacteria,1RRJ2@1236|Gammaproteobacteria,1J4YD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Malonate/sodium symporter MadM subunit madM - - - - - - - - - - - MadM DYD1_k127_1852862_7 247639.MGP2080_04540 6.15e-42 157.0 2CAQ0@1|root,32RRS@2|Bacteria,1RJ3J@1224|Proteobacteria,1S8E9@1236|Gammaproteobacteria,1JB74@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Malonate transporter MadL subunit madL - - - - - - - - - - - MadL DYD1_k127_1867327_0 395493.BegalDRAFT_0849 3.393e-233 745.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Large extracellular alpha-helical protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,LprI,MG1 DYD1_k127_1872216_0 1044.EH31_05300 1.502e-84 297.0 COG1858@1|root,COG1858@2|Bacteria,1QUP2@1224|Proteobacteria,2TW2M@28211|Alphaproteobacteria,2KCYB@204457|Sphingomonadales 204457|Sphingomonadales P ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS DYD1_k127_1872216_1 203122.Sde_2997 7.686e-20 94.0 COG1858@1|root,COG2931@1|root,COG1858@2|Bacteria,COG2931@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,465BG@72275|Alteromonadaceae 1236|Gammaproteobacteria P Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - CCP_MauG,UnbV_ASPIC,VCBS DYD1_k127_1888292_1 396588.Tgr7_0460 2.261e-42 158.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD1_k127_1888292_0 754476.Q7A_1557 2.516e-254 800.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,45ZT6@72273|Thiotrichales 72273|Thiotrichales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind DYD1_k127_1898100_0 1208321.D104_12620 4.434e-89 299.0 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,1S2RX@1236|Gammaproteobacteria,1XJ9T@135619|Oceanospirillales 135619|Oceanospirillales S membrane transporter protein - - - - - - - - - - - - TauE DYD1_k127_1898100_1 640081.Dsui_1528 2.9e-53 203.0 COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,2VI30@28216|Betaproteobacteria,2KVFA@206389|Rhodocyclales 206389|Rhodocyclales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07639 ko02020,map02020 M00446 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD1_k127_1902828_0 1392489.JPOL01000002_gene3065 5.748e-144 464.0 COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1HYXI@117743|Flavobacteriia,2XKDW@283735|Leeuwenhoekiella 976|Bacteroidetes H Aldolase/RraA - - - - - - - - - - - - RraA-like DYD1_k127_1902828_1 1346791.M529_14365 1.266e-109 358.0 COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,2TTJ7@28211|Alphaproteobacteria,2K0YY@204457|Sphingomonadales 204457|Sphingomonadales G Converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim DYD1_k127_1924516_1 1419583.V466_30340 6.095e-105 348.0 COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1RY8W@1236|Gammaproteobacteria,1YPQ7@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria P Belongs to the bacterial solute-binding protein 9 family - - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA DYD1_k127_1924516_2 1380394.JADL01000002_gene1358 3.451e-74 256.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria,2JQ8C@204441|Rhodospirillales 204441|Rhodospirillales P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system znuC - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC_tran DYD1_k127_1924516_0 1121451.DESAM_20780 4.059e-110 375.0 COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2X2BP@28221|Deltaproteobacteria,2M9TC@213115|Desulfovibrionales 28221|Deltaproteobacteria P ABC 3 transport family - - - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 DYD1_k127_1924516_3 1419583.V466_30325 7.703e-56 218.0 COG0803@1|root,COG0803@2|Bacteria,1N69A@1224|Proteobacteria,1SAUM@1236|Gammaproteobacteria,1YM7W@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria P Zinc-uptake complex component A periplasmic VPA0165 - - - - - - - - - - - ZnuA DYD1_k127_1924516_4 1207063.P24_08524 8.002e-53 192.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2TVD3@28211|Alphaproteobacteria,2JTHR@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the UPF0312 family - - - - - - - - - - - - YceI DYD1_k127_1976429_2 377629.TERTU_2565 3.744e-93 316.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,2PPUJ@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S RsgA GTPase rsgA2 - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase DYD1_k127_1976429_0 203122.Sde_0940 7.125e-228 716.0 COG1904@1|root,COG1904@2|Bacteria,1MVRI@1224|Proteobacteria,1RMRR@1236|Gammaproteobacteria,464VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucuronate isomerase uxaC GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528 UxaC DYD1_k127_1976429_1 876044.IMCC3088_194 5.59e-104 345.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,1J67A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G C4-dicarboxylate ABC transporter - - - - - - - - - - - - DctP DYD1_k127_1983989_1 1192759.AKIB01000026_gene2125 1.776e-34 150.0 COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria,2K9VJ@204457|Sphingomonadales 204457|Sphingomonadales S Ankyrin repeat - - - - - - - - - - - - Ank_2 DYD1_k127_1983989_0 1122194.AUHU01000002_gene2513 1.275e-81 287.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,467P9@72275|Alteromonadaceae 1236|Gammaproteobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 DYD1_k127_199066_5 882083.SacmaDRAFT_2658 4.976e-14 74.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_199066_0 1394178.AWOO02000036_gene8885 1.88e-103 342.0 COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EJBR@85012|Streptosporangiales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_199066_2 1068978.AMETH_3817 8.027e-95 320.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4DXKP@85010|Pseudonocardiales 201174|Actinobacteria P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_199066_4 402881.Plav_1139 2.466e-40 160.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,2TTM4@28211|Alphaproteobacteria,1JN6N@119043|Rhodobiaceae 28211|Alphaproteobacteria I Phospholipase D. Active site motifs. - - - - - - - - - - - - PLDc,PLDc_2,SNARE_assoc DYD1_k127_199066_1 1340493.JNIF01000003_gene2267 8.334e-96 323.0 2BZ6M@1|root,2Z7HW@2|Bacteria 2|Bacteria S InterPro IPR010496 - - - - - - - - - - - - DUF1080 DYD1_k127_199066_3 1502850.FG91_01562 6.356e-73 256.0 COG1835@1|root,COG1835@2|Bacteria,1PVUR@1224|Proteobacteria,2TTRB@28211|Alphaproteobacteria,2K98C@204457|Sphingomonadales 204457|Sphingomonadales I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 DYD1_k127_2012720_2 1283300.ATXB01000001_gene1778 4.911e-123 400.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1XDS1@135618|Methylococcales 135618|Methylococcales F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N DYD1_k127_2012720_3 666685.R2APBS1_2291 2.454e-110 364.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1X45V@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 DYD1_k127_2012720_0 396588.Tgr7_1182 1.718e-260 812.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales 135613|Chromatiales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase DYD1_k127_2012720_4 1049564.TevJSym_ap00790 4.482e-85 298.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1J5PD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C DYD1_k127_2012720_1 1049564.TevJSym_ap00800 8.529e-138 445.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1J4RX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197 ACCA DYD1_k127_2012720_5 1335757.SPICUR_04935 3.213e-46 175.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon DYD1_k127_2025245_2 1123242.JH636435_gene2777 8.581e-06 51.0 COG2319@1|root,COG4219@1|root,COG2319@2|Bacteria,COG4219@2|Bacteria,2IZRJ@203682|Planctomycetes 203682|Planctomycetes KT Antirepressor regulating drug resistance - - - - - - - - - - - - Peptidase_M56 DYD1_k127_2025245_1 1545915.JROG01000004_gene2009 1.307e-16 84.0 COG3682@1|root,COG3682@2|Bacteria,1RH6Y@1224|Proteobacteria,2U9MX@28211|Alphaproteobacteria,2KCHB@204457|Sphingomonadales 204457|Sphingomonadales K Transcriptional regulator - - - - - - - - - - - - Penicillinase_R DYD1_k127_2025245_0 566466.NOR53_856 2.413e-86 291.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,1J5MH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q and related enzymes yghX - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_2039386_0 234267.Acid_5827 5.19e-183 595.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_2039386_1 1340493.JNIF01000003_gene1475 2.543e-35 141.0 COG2960@1|root,COG2960@2|Bacteria 2|Bacteria M long-chain fatty acid transporting porin activity - - - - - - - - - - - - HXXSHH DYD1_k127_2046825_0 1161401.ASJA01000003_gene2792 4.891e-27 118.0 COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,43XAS@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_207241_1 1121937.AUHJ01000011_gene2889 6.438e-68 235.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - ko:K21430 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,GSDH DYD1_k127_207241_2 382464.ABSI01000010_gene3793 4.311e-28 121.0 COG3507@1|root,COG3507@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 43 family - - - - - - - - - - - - DUF1080 DYD1_k127_207241_0 338963.Pcar_0355 5.284e-80 271.0 COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,42Q4W@68525|delta/epsilon subdivisions,2WJ9H@28221|Deltaproteobacteria,43UJ3@69541|Desulfuromonadales 28221|Deltaproteobacteria I Squalene-hopene cyclase C-terminal domain shc-1 - 4.2.1.129,5.4.99.17,5.4.99.7 ko:K01852,ko:K06045 ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130 M00101 R03199,R07322,R07323 RC00874,RC01850,RC01851 ko00000,ko00001,ko00002,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N DYD1_k127_2081398_0 1122137.AQXF01000004_gene1584 5.563e-143 467.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U1C8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TonB-dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_2081398_1 314285.KT71_05632 2.024e-81 276.0 COG1917@1|root,COG1917@2|Bacteria,1QU6U@1224|Proteobacteria,1T1P4@1236|Gammaproteobacteria,1J7FW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S ChrR Cupin-like domain - - - - - - - - - - - - Cupin_7 DYD1_k127_2089628_1 1121374.KB891589_gene111 1.203e-18 90.0 COG1309@1|root,COG1309@2|Bacteria,1RG6C@1224|Proteobacteria,1SFNN@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_C_6,TetR_N DYD1_k127_2089628_0 392499.Swit_0730 5.505e-202 657.0 COG4206@1|root,COG4206@2|Bacteria,1QVV2@1224|Proteobacteria,2TWX0@28211|Alphaproteobacteria,2KEET@204457|Sphingomonadales 204457|Sphingomonadales H COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD1_k127_2091231_0 857087.Metme_1534 4.055e-113 376.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XE3C@135618|Methylococcales 135618|Methylococcales M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 DYD1_k127_2091231_2 1122165.AUHS01000002_gene2980 2.354e-14 79.0 COG2921@1|root,COG2921@2|Bacteria,1QBM4@1224|Proteobacteria,1T76Q@1236|Gammaproteobacteria,1JEZ3@118969|Legionellales 118969|Legionellales S Protein of unknown function (DUF493) - - - ko:K09158 - - - - ko00000 - - - DUF493 DYD1_k127_2091231_1 745411.B3C1_18411 6.814e-70 244.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1J5SC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - iECSF_1327.ECSF_0569,iSFV_1184.SFV_0696,iSFxv_1172.SFxv_0718 BPL_LplA_LipB DYD1_k127_2093438_1 1123053.AUDG01000033_gene815 4.633e-90 312.0 COG0332@1|root,COG0332@2|Bacteria,1NAGY@1224|Proteobacteria,1RN1T@1236|Gammaproteobacteria 1236|Gammaproteobacteria I synthase III - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C,Haem_oxygenas_2,ketoacyl-synt DYD1_k127_2093438_2 1123053.AUDG01000033_gene814 1.013e-67 235.0 2C4KU@1|root,32RE6@2|Bacteria,1RBD1@1224|Proteobacteria,1S1BE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2093438_0 1123355.JHYO01000013_gene1073 1.412e-145 483.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD1_k127_2093438_3 572477.Alvin_1242 6.85e-47 179.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,1WXU4@135613|Chromatiales 1236|Gammaproteobacteria T PFAM Metal-dependent hydrolase HDOD - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD DYD1_k127_2096827_1 237368.SCABRO_01640 8.622e-09 64.0 COG3608@1|root,COG3608@2|Bacteria 237368.SCABRO_01640|- G succinylglutamate desuccinylase aspartoacylase - - - - - - - - - - - - - DYD1_k127_2096827_0 237368.SCABRO_01641 7.064e-153 493.0 COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,2IYQF@203682|Planctomycetes 203682|Planctomycetes M Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD1_k127_2096827_2 670292.JH26_02885 2.868e-05 47.0 COG0515@1|root,COG0589@1|root,COG0515@2|Bacteria,COG0589@2|Bacteria,1MV1P@1224|Proteobacteria,2TQTS@28211|Alphaproteobacteria 28211|Alphaproteobacteria KLT serine threonine protein kinase MA20_09295 - - - - - - - - - - - Pkinase,Usp DYD1_k127_2108923_1 398578.Daci_4386 1.78e-100 331.0 COG0654@1|root,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,2VIVN@28216|Betaproteobacteria,4AC5F@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM monooxygenase FAD-binding - - 1.14.13.218 ko:K20940 ko00405,ko01130,map00405,map01130 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD1_k127_2108923_4 102129.Lepto7375DRAFT_6213 1.868e-38 148.0 COG2153@1|root,COG2153@2|Bacteria,1G6TQ@1117|Cyanobacteria,1HBVA@1150|Oscillatoriales 1117|Cyanobacteria S Acetyltransferase, gnat family - - - - - - - - - - - - Acetyltransf_10 DYD1_k127_2108923_7 472759.Nhal_3582 1.732e-26 111.0 COG0569@1|root,COG0569@2|Bacteria,1RIP2@1224|Proteobacteria,1SKEI@1236|Gammaproteobacteria,1X03Z@135613|Chromatiales 135613|Chromatiales P TrkA-C domain - - - - - - - - - - - - TrkA_C DYD1_k127_2108923_8 472759.Nhal_3582 2.955e-26 112.0 COG0569@1|root,COG0569@2|Bacteria,1RIP2@1224|Proteobacteria,1SKEI@1236|Gammaproteobacteria,1X03Z@135613|Chromatiales 135613|Chromatiales P TrkA-C domain - - - - - - - - - - - - TrkA_C DYD1_k127_2108923_6 502025.Hoch_6194 2.096e-32 132.0 COG3871@1|root,COG3871@2|Bacteria,1RF7K@1224|Proteobacteria,431CF@68525|delta/epsilon subdivisions,2WX0W@28221|Deltaproteobacteria,2Z189@29|Myxococcales 28221|Deltaproteobacteria S Pyridoxamine 5'-phosphate oxidase like - - - - - - - - - - - - Pyrid_ox_like DYD1_k127_2108923_5 349521.HCH_04956 4.161e-38 155.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1XK1Y@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein UspA and related nucleotide-binding ydaA - - ko:K14055 - - - - ko00000 - - - Usp DYD1_k127_2108923_2 1380355.JNIJ01000068_gene5658 2.08e-55 206.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,3JTPW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,TIR_2 DYD1_k127_2108923_0 1340493.JNIF01000003_gene3965 4.131e-111 374.0 COG1680@1|root,COG1680@2|Bacteria 2|Bacteria V peptidase activity - - - - - - - - - - - - Beta-lactamase DYD1_k127_2108923_3 543632.JOJL01000013_gene9332 7.857e-55 200.0 COG0627@1|root,COG0627@2|Bacteria,2I3VM@201174|Actinobacteria 201174|Actinobacteria S Tannase and feruloyl esterase - - - - - - - - - - - - Tannase DYD1_k127_2140425_0 33876.JNXY01000004_gene1370 4.016e-98 329.0 COG1506@1|root,COG1506@2|Bacteria,2H90U@201174|Actinobacteria 201174|Actinobacteria E Tannase and feruloyl esterase - - - - - - - - - - - - Tannase DYD1_k127_2140425_2 52598.EE36_09210 1.827e-23 104.0 COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,2TUFY@28211|Alphaproteobacteria,3ZWDG@60136|Sulfitobacter 28211|Alphaproteobacteria J Elongation factor SelB, winged helix selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 DYD1_k127_2145615_3 351348.Maqu_1547 9.041e-67 229.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,4642I@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2368 Seryl_tRNA_N,tRNA-synt_2b DYD1_k127_2145615_0 745411.B3C1_03520 6.449e-122 405.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5IY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system, permease component VP1997 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_2145615_1 1123253.AUBD01000002_gene1382 2.483e-89 308.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1X6BF@135614|Xanthomonadales 135614|Xanthomonadales V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_2145615_2 745411.B3C1_03530 4.4e-82 286.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1J86Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family macA - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_2145615_4 1121013.P873_07395 1.251e-17 92.0 29T5U@1|root,32E2F@2|Bacteria,1Q025@1224|Proteobacteria,1THEE@1236|Gammaproteobacteria,1XAG1@135614|Xanthomonadales 135614|Xanthomonadales S Yip1 domain - - - - - - - - - - - - Yip1 DYD1_k127_2147460_1 935261.JAGL01000044_gene2097 1.369e-142 464.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria,43NFB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.67 ko:K21802 ko00627,ko01120,map00627,map01120 - R05699 RC00075 ko00000,ko00001,ko01000 - - - Aldedh DYD1_k127_2147460_2 435908.IDSA_07940 5.85e-83 297.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,2QF1T@267893|Idiomarinaceae 1236|Gammaproteobacteria I Phospholipase D. Active site motifs. clsC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD1_k127_2147460_3 396588.Tgr7_1281 3.292e-53 188.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1X0ZV@135613|Chromatiales 135613|Chromatiales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4 DYD1_k127_2147460_4 472175.EL18_01181 7.88e-38 144.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,43JX8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C ferredoxin fdx - - ko:K04755 - - - - ko00000 - - - Fer2 DYD1_k127_2147460_0 1122137.AQXF01000007_gene3573 1.18e-152 491.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit MA20_01045 - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N DYD1_k127_2147784_0 396588.Tgr7_0817 0.0 1084.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales 135613|Chromatiales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD1_k127_2147784_2 243233.MCA0973 5.602e-73 254.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1XEWQ@135618|Methylococcales 135618|Methylococcales S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 DYD1_k127_2147784_1 1397528.Q671_17140 9.263e-108 361.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XHHX@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_2150506_2 243233.MCA2276 8.48e-13 79.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1XF2F@135618|Methylococcales 135618|Methylococcales L Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD1_k127_2150506_1 870187.Thini_4131 4.529e-80 275.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,4603D@72273|Thiotrichales 72273|Thiotrichales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD1_k127_2150506_0 349124.Hhal_0701 2.502e-141 457.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1WXRW@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit DYD1_k127_215110_5 715451.ambt_12015 1.397e-10 64.0 2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,1SGTK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_215110_4 1088721.NSU_2829 6.756e-22 101.0 2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2UH5V@28211|Alphaproteobacteria,2KBAD@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_215110_0 378806.STAUR_5205 3.29e-263 824.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YXXC@29|Myxococcales 28221|Deltaproteobacteria E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD1_k127_215110_1 861299.J421_3508 4.119e-148 482.0 COG2256@1|root,COG2256@2|Bacteria,1ZTCA@142182|Gemmatimonadetes 142182|Gemmatimonadetes L MgsA AAA+ ATPase C terminal - - - ko:K07478 - - - - ko00000 - - - AAA_assoc_2,MgsA_C,RuvB_N DYD1_k127_215110_2 485915.Dret_1267 1.983e-100 341.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2M8UK@213115|Desulfovibrionales 28221|Deltaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD1_k127_215110_3 1127673.GLIP_3550 1.758e-71 246.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RNQ7@1236|Gammaproteobacteria,468IG@72275|Alteromonadaceae 1236|Gammaproteobacteria V MatE yeeO GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - - - - - - - - - - MatE DYD1_k127_2154480_1 1267535.KB906767_gene4320 8.605e-41 163.0 COG0491@1|root,COG0491@2|Bacteria,3Y48F@57723|Acidobacteria,2JIRT@204432|Acidobacteriia 204432|Acidobacteriia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_2154480_0 886293.Sinac_1153 1.938e-182 602.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_2154480_2 627192.SLG_31400 3.093e-30 130.0 COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_2174606_1 395493.BegalDRAFT_2442 4.414e-15 86.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,462ER@72273|Thiotrichales 72273|Thiotrichales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL DYD1_k127_2174606_3 748658.KB907312_gene1390 1.368e-07 61.0 COG3149@1|root,COG3149@2|Bacteria 2|Bacteria U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM DYD1_k127_2174606_2 1202962.KB907182_gene210 1.156e-11 74.0 2CBG9@1|root,32RTB@2|Bacteria,1R86M@1224|Proteobacteria,1RNNN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type II secretion system, protein N gspN GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02463 ko05111,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSN DYD1_k127_2174606_0 1123261.AXDW01000006_gene2409 5.29e-169 564.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1X3M3@135614|Xanthomonadales 135614|Xanthomonadales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C DYD1_k127_217537_2 1249627.D779_0542 1.31e-64 225.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1WW0B@135613|Chromatiales 135613|Chromatiales P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD1_k127_217537_1 153948.NAL212_2196 5.519e-100 339.0 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin DYD1_k127_217537_0 1049564.TevJSym_an00380 8.605e-159 514.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1J4EJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the pyruvate kinase family pykA GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 PK,PK_C DYD1_k127_217537_3 511062.GU3_02805 1.193e-21 96.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,1RPKA@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Hydroxypyruvate reductase ttuD - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL DYD1_k127_2195912_2 1249627.D779_1660 9.243e-05 46.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales 135613|Chromatiales L Helicase - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2 DYD1_k127_2195912_0 1123253.AUBD01000005_gene111 3.344e-272 847.0 COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1X482@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N DYD1_k127_2195912_1 240016.ABIZ01000001_gene3902 2.608e-55 201.0 COG2960@1|root,COG2960@2|Bacteria,46UCE@74201|Verrucomicrobia,2IVAW@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_2196901_1 1177154.Y5S_01475 2.278e-91 306.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XHJ0@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b DYD1_k127_2196901_0 713586.KB900536_gene1195 2.283e-102 352.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1WX4H@135613|Chromatiales 135613|Chromatiales M PFAM peptidase - - - - - - - - - - - - OapA,Peptidase_M23 DYD1_k127_2196901_2 563040.Saut_2021 2.035e-27 115.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,42RT7@68525|delta/epsilon subdivisions,2YRF9@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK DYD1_k127_2204792_1 1232410.KI421413_gene569 9.563e-42 163.0 COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,42SMK@68525|delta/epsilon subdivisions,2WSC2@28221|Deltaproteobacteria,43TI9@69541|Desulfuromonadales 28221|Deltaproteobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD1_k127_2204792_0 768671.ThimaDRAFT_2966 2.56e-140 460.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH DYD1_k127_2206632_2 243233.MCA2596 1.736e-05 49.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1XFYM@135618|Methylococcales 135618|Methylococcales L HNH endonuclease - - - - - - - - - - - - HNH_5 DYD1_k127_2206632_1 1238182.C882_2989 3.239e-65 233.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,2TSPG@28211|Alphaproteobacteria,2JRPX@204441|Rhodospirillales 204441|Rhodospirillales S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans DYD1_k127_2206632_0 1304275.C41B8_10043 1.812e-89 299.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadI - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD1_k127_2206706_2 247633.GP2143_14311 9.716e-90 309.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria,1JAB2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG3202 ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC DYD1_k127_2206706_3 1121033.AUCF01000011_gene1829 4.878e-72 254.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2U0CA@28211|Alphaproteobacteria,2JS5Q@204441|Rhodospirillales 204441|Rhodospirillales G Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase DYD1_k127_2206706_7 396588.Tgr7_3049 2.272e-14 77.0 COG5481@1|root,COG5481@2|Bacteria 2|Bacteria S small protein containing a coiled-coil domain MA20_03740 - - - - - - - - - - - DUF465 DYD1_k127_2206706_1 243233.MCA2983 2.807e-92 313.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1XF6C@135618|Methylococcales 135618|Methylococcales P Inositol monophosphatase family - - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P DYD1_k127_2206706_5 1122201.AUAZ01000006_gene3888 6.104e-59 212.0 COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria,466G1@72275|Alteromonadaceae 1236|Gammaproteobacteria S Haloacid dehalogenase-like hydrolase yrfG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase DYD1_k127_2206706_0 1158150.KB906241_gene665 8.104e-160 518.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales 135613|Chromatiales L DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB - 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C DYD1_k127_2206706_6 1283284.AZUK01000001_gene931 2.607e-44 164.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1Y4G7@135624|Aeromonadales 135624|Aeromonadales O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_2206706_4 1265313.HRUBRA_01364 2.895e-67 235.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1J4QP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind DYD1_k127_2214125_0 1123020.AUIE01000003_gene478 6.987e-142 464.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1YDWN@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0012501,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016779,GO:0019200,GO:0033692,GO:0033785,GO:0033786,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0070566,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272,ko:K21344 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECH74115_1262.ECH74115_4363,iECSP_1301.ECSP_4025,iECs_1301.ECs3935,iPC815.YPO0654,iZ_1308.Z4405 CTP_transf_like,PfkB DYD1_k127_2218314_1 926566.Terro_1070 5.414e-22 103.0 COG1661@1|root,COG1661@2|Bacteria,3Y4JP@57723|Acidobacteria,2JJAA@204432|Acidobacteriia 204432|Acidobacteriia S Domain of unknown function (DUF296) - - - ko:K06934 - - - - ko00000 - - - DUF296 DYD1_k127_2218314_4 266779.Meso_2898 5.618e-18 90.0 2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2218314_0 1122164.JHWF01000019_gene483 1.515e-71 257.0 COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_4,PAS_9,dCache_1 DYD1_k127_2218314_3 1504672.669784392 4.738e-18 91.0 COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria,4AJWM@80864|Comamonadaceae 28216|Betaproteobacteria T Response regulator receiver domain - - - ko:K02485 - - - - ko00000,ko02022 - - - Response_reg DYD1_k127_2218314_2 460265.Mnod_1231 1.074e-19 91.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD1_k127_2223495_1 864051.BurJ1DRAFT_1491 1.986e-48 178.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,1KJN5@119065|unclassified Burkholderiales 28216|Betaproteobacteria F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT DYD1_k127_2223495_0 1429851.X548_12260 9.855e-166 539.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1X4XY@135614|Xanthomonadales 135614|Xanthomonadales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C DYD1_k127_2243766_2 1286631.X805_21830 3.915e-57 205.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,1KKN2@119065|unclassified Burkholderiales 28216|Betaproteobacteria D Maf-like protein yceF - - ko:K06287 - - - - ko00000 - - - Maf DYD1_k127_2243766_1 395493.BegalDRAFT_0576 1.009e-92 314.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,45ZNQ@72273|Thiotrichales 72273|Thiotrichales J Responsible for synthesis of pseudouridine from uracil - - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_2243766_0 765912.Thimo_0531 1.317e-217 693.0 COG1530@1|root,COG3266@1|root,COG1530@2|Bacteria,COG3266@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1WXN6@135613|Chromatiales 135613|Chromatiales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD1_k127_2254439_3 1116375.VEJY3_16306 0.0002586 53.0 COG0810@1|root,COG0810@2|Bacteria,1R4VE@1224|Proteobacteria,1RQPV@1236|Gammaproteobacteria,1XTNF@135623|Vibrionales 135623|Vibrionales U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins tonB - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD1_k127_2254439_1 1042377.AFPJ01000037_gene2919 4.463e-63 224.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,466IP@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain cpxR - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_2254439_0 1266925.JHVX01000001_gene2576 1.218e-65 241.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2WEJE@28216|Betaproteobacteria,372ZN@32003|Nitrosomonadales 28216|Betaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain cpxA - 2.7.13.3 ko:K02484,ko:K07640,ko:K07642 ko01503,ko02020,map01503,map02020 M00447,M00450,M00645,M00646,M00648,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_2254439_2 247634.GPB2148_1751 1.58e-25 108.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1J53P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp DYD1_k127_2257463_0 1212548.B381_17474 1.54e-157 500.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1Z1Y1@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases IV02_03800 - - - - - - - - - - - GSDH DYD1_k127_2257463_1 404589.Anae109_1775 8.5e-74 255.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,42ZD0@68525|delta/epsilon subdivisions,2WU4P@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK - 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK DYD1_k127_2261159_3 278963.ATWD01000001_gene1733 2.599e-14 85.0 COG0497@1|root,COG0497@2|Bacteria,3Y6KC@57723|Acidobacteria,2JME0@204432|Acidobacteriia 204432|Acidobacteriia L DNA recombination - - - - - - - - - - - - - DYD1_k127_2261159_2 314287.GB2207_02437 7.013e-74 258.0 COG0596@1|root,COG0596@2|Bacteria,1QTWQ@1224|Proteobacteria,1T1JQ@1236|Gammaproteobacteria,1J6EG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_2261159_0 1120983.KB894576_gene3460 5.974e-202 646.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transport system fused permease components - - - - - - - - - - - - DctM DYD1_k127_2261159_1 89187.ISM_08580 2.894e-191 615.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,46NT3@74030|Roseovarius 28211|Alphaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD1_k127_2261159_4 634452.APA01_15220 5.037e-12 67.0 COG1506@1|root,COG1506@2|Bacteria,1R968@1224|Proteobacteria,2TXT1@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Tannase and feruloyl esterase - - - - - - - - - - - - Tannase DYD1_k127_2263611_2 530564.Psta_3145 9.917e-30 123.0 COG1005@1|root,COG1005@2|Bacteria,2IXUX@203682|Planctomycetes 203682|Planctomycetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_2263611_5 1123253.AUBD01000005_gene200 6.002e-25 109.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1X4DK@135614|Xanthomonadales 135614|Xanthomonadales F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Ham1p_like DYD1_k127_2263611_3 765912.Thimo_0079 2.049e-28 116.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales 135613|Chromatiales J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 DYD1_k127_2263611_0 1049564.TevJSym_bb00110 6.086e-190 604.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1J4ZB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the citrate synthase family gltA GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_00727 Citrate_synt DYD1_k127_2263611_1 519989.ECTPHS_06512 3.583e-35 145.0 COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,1S81F@1236|Gammaproteobacteria,1X2NE@135613|Chromatiales 135613|Chromatiales S mRNA catabolic process - - - - - - - - - - - - - DYD1_k127_2263611_4 1121921.KB898709_gene173 1.555e-27 116.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,2PN7K@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M Penicillin-binding protein OB-like domain mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase DYD1_k127_2267300_1 1122194.AUHU01000003_gene2202 7.586e-94 316.0 COG3693@1|root,COG3693@2|Bacteria,1PX42@1224|Proteobacteria,1RQ0K@1236|Gammaproteobacteria,46781@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glycosyl hydrolase family 10 - - 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - Glyco_hydro_10 DYD1_k127_2267300_2 439235.Dalk_3478 4.946e-73 258.0 COG3108@1|root,COG3108@2|Bacteria,1RAMQ@1224|Proteobacteria 1224|Proteobacteria S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 DYD1_k127_2267300_0 225937.HP15_2647 4.623e-118 387.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD DYD1_k127_2272110_1 391625.PPSIR1_20659 1.523e-90 306.0 KOG1584@1|root,32BW5@2|Bacteria,1PW91@1224|Proteobacteria,42YNQ@68525|delta/epsilon subdivisions,2WTQC@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 DYD1_k127_2272110_0 1469607.KK073768_gene3658 2.448e-108 365.0 COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1HJYZ@1161|Nostocales 1117|Cyanobacteria P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA DYD1_k127_2272110_2 1254432.SCE1572_30075 1.991e-41 159.0 COG0715@1|root,COG0715@2|Bacteria,1REGQ@1224|Proteobacteria,42WDM@68525|delta/epsilon subdivisions,2WRGC@28221|Deltaproteobacteria,2Z2KP@29|Myxococcales 28221|Deltaproteobacteria P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_2276790_6 637389.Acaty_c1133 4.804e-21 94.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,2NC5F@225057|Acidithiobacillales 225057|Acidithiobacillales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM DYD1_k127_2276790_2 522306.CAP2UW1_2108 4.735e-91 306.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,1KPSQ@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM DYD1_k127_2276790_4 1123236.KB899379_gene1397 4.382e-66 228.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,466Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK DYD1_k127_2276790_5 55601.VANGNB10_cI0665 2.216e-42 160.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,1XXFW@135623|Vibrionales 135623|Vibrionales C Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn DYD1_k127_2276790_7 1123256.KB907926_gene1031 1.368e-11 70.0 COG0822@1|root,COG0822@2|Bacteria,1QBQ9@1224|Proteobacteria,1T7AA@1236|Gammaproteobacteria,1X90R@135614|Xanthomonadales 135614|Xanthomonadales C NifU-like N terminal domain - - - - - - - - - - - - NifU_N DYD1_k127_2276790_0 1209072.ALBT01000013_gene3598 9.127e-106 357.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1FGPP@10|Cellvibrio 1236|Gammaproteobacteria E Aminotransferase class-V iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - iPC815.YPO2896,iYL1228.KPN_02862 Aminotran_5 DYD1_k127_2276790_3 1123368.AUIS01000004_gene248 3.794e-71 248.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,2NBQP@225057|Acidithiobacillales 225057|Acidithiobacillales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD1_k127_2276790_1 768671.ThimaDRAFT_0736 9.655e-92 318.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales 135613|Chromatiales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P DYD1_k127_2292037_2 1026882.MAMP_02597 2.055e-89 312.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,45ZQ0@72273|Thiotrichales 72273|Thiotrichales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N DYD1_k127_2292037_1 1122603.ATVI01000009_gene2590 1.547e-104 350.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1X2ZP@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA DYD1_k127_2292037_4 1049564.TevJSym_aa00390 6.164e-74 272.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1J4UT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD DYD1_k127_2292037_3 572477.Alvin_2150 1.666e-82 293.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1WVWS@135613|Chromatiales 135613|Chromatiales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos DYD1_k127_2292037_5 1120965.AUBV01000004_gene710 1.67e-68 237.0 COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia 976|Bacteroidetes G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO DYD1_k127_2292037_0 1123253.AUBD01000001_gene1572 6.296e-136 450.0 COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1X3FQ@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 DYD1_k127_2292037_6 1313301.AUGC01000007_gene629 1.012e-36 146.0 COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes 976|Bacteroidetes CH Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid kmo - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD1_k127_2294919_0 1121013.P873_11245 1.942e-77 268.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1XCGD@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 DYD1_k127_2294919_1 551789.ATVJ01000001_gene1037 4.844e-29 131.0 28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2294919_2 247639.MGP2080_01801 9.541e-26 118.0 COG3450@1|root,COG3450@2|Bacteria,1N1GM@1224|Proteobacteria,1SIWX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S enzyme of the cupin superfamily - - - - - - - - - - - - Cupin_3 DYD1_k127_2332348_3 886293.Sinac_1153 8.488e-50 182.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_2332348_1 159087.Daro_2048 3.467e-114 396.0 COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVRJ@206389|Rhodocyclales 206389|Rhodocyclales T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS,Response_reg DYD1_k127_2332348_4 198628.Dda3937_03089 5.215e-17 89.0 COG3751@1|root,COG3751@2|Bacteria,1N2TX@1224|Proteobacteria,1SASI@1236|Gammaproteobacteria 1236|Gammaproteobacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_3 DYD1_k127_2332348_5 649349.Lbys_1338 2.467e-06 50.0 COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,47RIT@768503|Cytophagia 976|Bacteroidetes L Site-specific recombinase, DNA invertase Pin - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom DYD1_k127_2332348_0 1121937.AUHJ01000018_gene268 2.887e-196 634.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,464C0@72275|Alteromonadaceae 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 DYD1_k127_2332348_2 1268237.G114_05425 3.354e-62 223.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1Y3F2@135624|Aeromonadales 135624|Aeromonadales J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind DYD1_k127_2336816_0 1260251.SPISAL_01500 2.978e-240 747.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1WWX1@135613|Chromatiales 135613|Chromatiales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 DYD1_k127_2336816_2 1123399.AQVE01000004_gene2507 1.112e-50 184.0 COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria 1236|Gammaproteobacteria O oxidase, assembly ctaG - - ko:K02258 ko00190,ko01100,ko04714,map00190,map01100,map04714 M00154 - - ko00000,ko00001,ko00002,ko03029 3.D.4.8 - - CtaG_Cox11 DYD1_k127_2336816_1 745411.B3C1_01735 9.704e-109 361.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1J4UE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 coxC - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 DYD1_k127_2336816_3 596153.Alide_3482 4.452e-08 56.0 2E53D@1|root,32ZWH@2|Bacteria,1N979@1224|Proteobacteria,2VVRY@28216|Betaproteobacteria,4AFBB@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF2909) - - - - - - - - - - - - DUF2909 DYD1_k127_2336816_4 1283300.ATXB01000001_gene1082 3.519e-07 58.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1XEXY@135618|Methylococcales 135618|Methylococcales S SURF1-like protein - - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 DYD1_k127_2344641_1 713587.THITH_07495 2.141e-49 187.0 COG2230@1|root,COG2230@2|Bacteria 2|Bacteria M cyclopropane-fatty-acyl-phospholipid synthase - - 2.1.1.157 ko:K18897,ko:K20444 ko00260,map00260 - R10061 RC00003,RC03040 ko00000,ko00001,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - CMAS,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25 DYD1_k127_2344641_2 1227349.C170_19980 1.985e-40 155.0 COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,4HG6C@91061|Bacilli,26XIE@186822|Paenibacillaceae 91061|Bacilli K Acetyltransferase - - - - - - - - - - - - Acetyltransf_3 DYD1_k127_2344641_0 1342302.JASC01000013_gene2890 3.167e-116 383.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3ZV3G@60136|Sulfitobacter 28211|Alphaproteobacteria S Putative cyclase MA20_36465 - - - - - - - - - - - Cyclase DYD1_k127_2357430_3 317025.Tcr_2009 4.37e-27 117.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,4607X@72273|Thiotrichales 72273|Thiotrichales JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C DYD1_k127_2357430_1 686340.Metal_2066 2.015e-193 614.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1XER8@135618|Methylococcales 135618|Methylococcales JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C DYD1_k127_2357430_0 1396858.Q666_05660 2.4e-245 775.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPN9@1236|Gammaproteobacteria,464QS@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ybiT GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - - - - - - - - - - ABC_tran,ABC_tran_Xtn DYD1_k127_2357430_2 543728.Vapar_0253 6.012e-31 133.0 COG2974@1|root,COG2974@2|Bacteria,1MXPR@1224|Proteobacteria,2VHD8@28216|Betaproteobacteria,4AA6Q@80864|Comamonadaceae 28216|Betaproteobacteria L May be involved in recombination rdgC - - ko:K03554 - - - - ko00000,ko03400 - - - RdgC DYD1_k127_2361391_3 1304275.C41B8_15932 8.457e-12 69.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state bepA GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48,TPR_19 DYD1_k127_2361391_1 187272.Mlg_2480 6.789e-59 207.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WY4F@135613|Chromatiales 135613|Chromatiales O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD1_k127_2361391_2 314278.NB231_12364 2.887e-52 189.0 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1WWJB@135613|Chromatiales 135613|Chromatiales E PFAM Amino acid-binding ACT - - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 DYD1_k127_2361391_0 768671.ThimaDRAFT_0039 1.426e-102 342.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1WWMV@135613|Chromatiales 135613|Chromatiales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD1_k127_2374462_1 452637.Oter_1367 3.84e-80 272.0 COG0262@1|root,COG0262@2|Bacteria,46XD6@74201|Verrucomicrobia,3K9XY@414999|Opitutae 414999|Opitutae H PFAM bifunctional deaminase-reductase domain protein - - - - - - - - - - - - RibD_C DYD1_k127_2374462_0 243233.MCA0673 0.0 1480.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1XEG1@135618|Methylococcales 135618|Methylococcales F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 DYD1_k127_2374462_2 1123279.ATUS01000001_gene1185 6.051e-67 236.0 COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,1J5H6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Beta-lactamase superfamily I yycJ - - - - - - - - - - - Lactamase_B_2 DYD1_k127_2374462_4 1260251.SPISAL_05310 1.047e-38 147.0 COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1WZ3B@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF1820) - - - - - - - - - - - - DUF1820 DYD1_k127_2374462_3 1123399.AQVE01000004_gene2618 3.75e-39 162.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1S0GX@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Type VI secretion fha1 - - ko:K07169,ko:K11894,ko:K11913 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko02044 3.A.23.1 - - FHA DYD1_k127_2374462_5 595460.RRSWK_04882 1.631e-26 112.0 COG0631@1|root,COG0631@2|Bacteria 2|Bacteria T protein serine/threonine phosphatase activity - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 DYD1_k127_2385546_6 543728.Vapar_0952 3.585e-08 59.0 2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria,4AE1N@80864|Comamonadaceae 28216|Betaproteobacteria S TIGRFAM MJ0042 family finger-like protein - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 DYD1_k127_2385546_2 765911.Thivi_1103 1.854e-57 217.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1WX2W@135613|Chromatiales 135613|Chromatiales J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA DYD1_k127_2385546_0 472759.Nhal_3561 3.391e-229 715.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1WWPY@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD1_k127_2385546_4 675806.VII_003431 2.997e-46 176.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1XWV0@135623|Vibrionales 135623|Vibrionales I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl DYD1_k127_2385546_3 1286106.MPL1_04352 3.106e-56 199.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,460Q7@72273|Thiotrichales 72273|Thiotrichales E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II DYD1_k127_2385546_5 748247.AZKH_3744 2.091e-21 102.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity mauD - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA DYD1_k127_2385546_1 768671.ThimaDRAFT_4023 1.668e-135 445.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales 135613|Chromatiales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 DYD1_k127_2407011_3 1231190.NA8A_16271 1.686e-82 281.0 COG1638@1|root,COG1638@2|Bacteria,1MUJY@1224|Proteobacteria,2TQNU@28211|Alphaproteobacteria,43K56@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP DYD1_k127_2407011_0 648757.Rvan_1614 1.162e-155 497.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,3N642@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain yqjG GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 DYD1_k127_2407011_2 1123279.ATUS01000001_gene2455 2.646e-93 316.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RZ5E@1236|Gammaproteobacteria,1J8I4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H ApbE family - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE DYD1_k127_2407011_1 1122134.KB893650_gene144 1.679e-113 380.0 COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,1XHI3@135619|Oceanospirillales 135619|Oceanospirillales I Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 DYD1_k127_2418399_7 935840.JAEQ01000003_gene279 1.269e-08 56.0 COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Aminomethyltransferase folate-binding domain - - 2.1.1.341 ko:K15066 ko00627,ko01120,map00627,map01120 - R09271,R10136 RC00113,RC00392 ko00000,ko00001,ko01000 - - - GCV_T,GCV_T_C DYD1_k127_2418399_5 288000.BBta_2401 2.015e-21 98.0 COG2259@1|root,COG2259@2|Bacteria,1RCKY@1224|Proteobacteria,2U6KP@28211|Alphaproteobacteria,3JYKN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX DYD1_k127_2418399_2 1267534.KB906756_gene693 9.786e-35 145.0 COG0491@1|root,COG0491@2|Bacteria,3Y48F@57723|Acidobacteria,2JIRT@204432|Acidobacteriia 204432|Acidobacteriia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_2418399_3 1349767.GJA_3140 3.488e-33 138.0 COG4758@1|root,COG4758@2|Bacteria,1RFX6@1224|Proteobacteria,2WCSU@28216|Betaproteobacteria,4772Z@75682|Oxalobacteraceae 28216|Betaproteobacteria S membrane - - - - - - - - - - - - - DYD1_k127_2418399_6 1236514.BAKL01000001_gene160 2.195e-09 64.0 COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,2FMXH@200643|Bacteroidia,4AM3S@815|Bacteroidaceae 976|Bacteroidetes S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - DUF2154 DYD1_k127_2418399_1 1267535.KB906767_gene5071 4.41e-68 244.0 COG2972@1|root,COG2972@2|Bacteria,3Y4BE@57723|Acidobacteria,2JMFY@204432|Acidobacteriia 204432|Acidobacteriia T Histidine kinase - - - - - - - - - - - - His_kinase DYD1_k127_2418399_0 204669.Acid345_3487 3.057e-80 275.0 COG3279@1|root,COG3279@2|Bacteria,3Y3B3@57723|Acidobacteria,2JP1W@204432|Acidobacteriia 204432|Acidobacteriia KT LytTr DNA-binding domain - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg DYD1_k127_2418399_4 5722.XP_001317643.1 1.862e-21 107.0 COG0666@1|root,KOG0504@2759|Eukaryota 2759|Eukaryota I protein ubiquitination - - - ko:K15502,ko:K15503 - - - - ko00000,ko01009,ko03400 - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447 DYD1_k127_2436858_0 472759.Nhal_1208 1.813e-160 512.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1WWIP@135613|Chromatiales 135613|Chromatiales S 2-methylcitrate dehydratase prpD - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD DYD1_k127_2436858_1 1547437.LL06_05060 8.261e-21 96.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria,43J9P@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V COG1136 ABC-type antimicrobial peptide transport system ATPase component - - - ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - ABC_tran DYD1_k127_2453908_0 4787.PITG_09985T0 1.172e-223 724.0 COG0265@1|root,KOG1421@2759|Eukaryota,3Q7R9@4776|Peronosporales 4776|Peronosporales O negative regulation of hippo signaling - - - - - - - - - - - - PDZ_1,Trypsin_2 DYD1_k127_2453908_1 1397528.Q671_03230 5.778e-06 50.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XHGC@135619|Oceanospirillales 135619|Oceanospirillales CH hydroxylase ubiF - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD1_k127_2455314_1 555793.WSK_0889 7.563e-271 839.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,2K22T@204457|Sphingomonadales 204457|Sphingomonadales P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_2455314_0 1123269.NX02_23880 0.0 1226.0 COG3386@1|root,COG3386@2|Bacteria,1R5SU@1224|Proteobacteria,2VFDB@28211|Alphaproteobacteria,2KDWD@204457|Sphingomonadales 204457|Sphingomonadales G Pectate lyase superfamily protein - - - - - - - - - - - - Pectate_lyase_3,SGL DYD1_k127_2455314_2 1121022.ABENE_07120 1.749e-57 213.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - DYD1_k127_2456346_1 1128912.GMES_3470 1.5e-90 311.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,465JT@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase fixL - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd,Response_reg DYD1_k127_2456346_2 1294143.H681_20340 1.478e-62 226.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria 1236|Gammaproteobacteria T universal stress protein ydaA - - ko:K14055 - - - - ko00000 - - - Usp DYD1_k127_2456346_0 1121374.KB891586_gene2542 1.982e-157 509.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD1_k127_2473122_7 301.JNHE01000015_gene4429 2.953e-30 125.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RZ0M@1236|Gammaproteobacteria,1YKRI@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H HemY protein N-terminus hemY - - ko:K02498 - - - - ko00000 - - - HemY_N DYD1_k127_2473122_4 391615.ABSJ01000039_gene1861 1.656e-67 236.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1J6UB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D AAA domain - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA DYD1_k127_2473122_0 545264.KB898744_gene2276 1.242e-230 723.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RNH8@1236|Gammaproteobacteria,1WWBG@135613|Chromatiales 135613|Chromatiales H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis ubiD - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_2473122_3 1294143.H681_23980 6.399e-74 257.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase DYD1_k127_2473122_6 519989.ECTPHS_00894 6.851e-39 154.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales 135613|Chromatiales S Protein of unknown function, DUF484 - - - ko:K09921 - - - - ko00000 - - - DUF484 DYD1_k127_2473122_1 1249627.D779_3723 9.257e-99 331.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1WW4W@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_2473122_2 713587.THITH_00525 1.058e-75 257.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1WVXJ@135613|Chromatiales 135613|Chromatiales O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome DYD1_k127_2473122_5 765911.Thivi_1735 1.083e-55 196.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales 135613|Chromatiales O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small DYD1_k127_2475540_0 234267.Acid_5827 4.046e-151 490.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_2475540_1 234267.Acid_2032 9.58e-132 434.0 COG2960@1|root,COG2960@2|Bacteria 2|Bacteria M long-chain fatty acid transporting porin activity - - - - - - - - - - - - HXXSHH DYD1_k127_2502313_0 765910.MARPU_09870 9.308e-70 246.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1WXJR@135613|Chromatiales 135613|Chromatiales G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase DYD1_k127_2502313_1 1122951.ATUE01000005_gene2200 2.326e-63 226.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,3NJAU@468|Moraxellaceae 1236|Gammaproteobacteria L May be involved in recombinational repair of damaged DNA recN GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N DYD1_k127_2528315_3 1033802.SSPSH_001328 1.46e-46 177.0 COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,1SDNN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 DYD1_k127_2528315_0 697282.Mettu_0354 2.126e-118 403.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Zn-dependent protease with chaperone function htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 DYD1_k127_2528315_2 697282.Mettu_0353 1.071e-77 266.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA DYD1_k127_2528315_1 396588.Tgr7_0552 2.133e-96 328.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WWAK@135613|Chromatiales 135613|Chromatiales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE DYD1_k127_2531543_0 1219045.BV98_002756 2.97e-167 556.0 COG1629@1|root,COG4771@2|Bacteria,1R4SS@1224|Proteobacteria 1224|Proteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_2541074_4 1040989.AWZU01000029_gene4335 9.583e-09 61.0 2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,3K43P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2541074_2 1007104.SUS17_2461 1.911e-87 304.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales 204457|Sphingomonadales G glucose sorbosone - - - - - - - - - - - - GSDH DYD1_k127_2541074_3 1304872.JAGC01000009_gene620 2.343e-77 278.0 COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2M7ZK@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Peptidase M23 - - - - - - - - - - - - Peptidase_M23 DYD1_k127_2541074_1 203122.Sde_1706 6.489e-185 586.0 COG0738@1|root,COG0738@2|Bacteria,1R3UK@1224|Proteobacteria,1RZ2I@1236|Gammaproteobacteria,46650@72275|Alteromonadaceae 1236|Gammaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_2541074_0 1340493.JNIF01000004_gene920 2.144e-186 610.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - - - - - - - - - - - PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5 DYD1_k127_2546408_1 745014.OMB55_00000750 1.815e-11 70.0 28MBM@1|root,2ZAQ2@2|Bacteria,1R5V6@1224|Proteobacteria,1S0K0@1236|Gammaproteobacteria,1J5EM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2546408_0 369723.Strop_0048 7.242e-15 85.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DAUE@85008|Micromonosporales 201174|Actinobacteria KLT serine threonine protein kinase pknB GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase DYD1_k127_2546408_2 1411685.U062_00808 9.362e-07 59.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,1J5XV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 DYD1_k127_2558823_0 2340.JV46_14860 1.188e-249 780.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,1J4MJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CI COG5016 Pyruvate oxaloacetate carboxyltransferase oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA DYD1_k127_2558823_1 765910.MARPU_07645 5.594e-11 63.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1WVXS@135613|Chromatiales 135613|Chromatiales C decarboxylase beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta DYD1_k127_2559353_0 292415.Tbd_1051 1.528e-109 371.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria 28216|Betaproteobacteria I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD1_k127_2571472_0 1532558.JL39_05985 7.487e-46 171.0 COG3963@1|root,COG3963@2|Bacteria,1R904@1224|Proteobacteria,2VGE8@28211|Alphaproteobacteria,4BNJ3@82115|Rhizobiaceae 28211|Alphaproteobacteria I Methyltransferase domain - - - - - - - - - - - - Methyltransf_25,RrnaAD DYD1_k127_2571472_3 196490.AUEZ01000017_gene3220 1.564e-11 65.0 COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2TTXF@28211|Alphaproteobacteria,3JRB1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 DYD1_k127_2571472_2 1095769.CAHF01000021_gene943 2.015e-26 115.0 COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2VVC1@28216|Betaproteobacteria 28216|Betaproteobacteria E Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 DYD1_k127_2571472_1 159087.Daro_0623 1.808e-42 158.0 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,2KX2P@206389|Rhodocyclales 206389|Rhodocyclales S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD1_k127_2575573_4 765911.Thivi_4286 0.0001032 45.0 COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,1WX78@135613|Chromatiales 135613|Chromatiales C Protein of unknown function (DUF3501) - - - - - - - - - - - - DUF3501 DYD1_k127_2575573_1 2340.JV46_29190 4.545e-303 939.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1J4HN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD1_k127_2575573_0 713586.KB900536_gene926 2.391e-314 978.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV DYD1_k127_2575573_2 105559.Nwat_2727 5.754e-85 308.0 COG0784@1|root,COG2199@1|root,COG2200@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales 135613|Chromatiales T PFAM EAL domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg DYD1_k127_2575573_3 1123256.KB907937_gene1890 7.64e-76 259.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1X3RU@135614|Xanthomonadales 135614|Xanthomonadales E lysine 2,3-aminomutase - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM DYD1_k127_2586221_2 629773.AORY01000002_gene1423 2.747e-07 55.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales 204457|Sphingomonadales V Secretion protein, HlyD - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_2586221_0 1121403.AUCV01000001_gene1000 5.043e-33 143.0 COG1846@1|root,COG1846@2|Bacteria,1N75F@1224|Proteobacteria,42VDI@68525|delta/epsilon subdivisions,2WR80@28221|Deltaproteobacteria,2MK08@213118|Desulfobacterales 28221|Deltaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 DYD1_k127_2586221_1 290317.Cpha266_0806 4.325e-27 124.0 COG0679@1|root,COG0679@2|Bacteria 2|Bacteria S auxin-activated signaling pathway - - - ko:K07088 - - - - ko00000 - - - Mem_trans DYD1_k127_2602555_1 1123368.AUIS01000001_gene2024 8.692e-37 145.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,2NC0C@225057|Acidithiobacillales 225057|Acidithiobacillales S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 DYD1_k127_2602555_0 84531.JMTZ01000044_gene983 1.928e-41 160.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1X68Z@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf DYD1_k127_2602555_2 857087.Metme_1677 6.31e-10 64.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XDR3@135618|Methylococcales 135618|Methylococcales K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 DYD1_k127_2605922_2 1479237.JMLY01000001_gene1131 3.083e-21 107.0 COG0457@1|root,COG0457@2|Bacteria,1N8R8@1224|Proteobacteria,1SBTP@1236|Gammaproteobacteria,468VH@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16 DYD1_k127_2605922_0 118173.KB235914_gene936 2.241e-52 188.0 COG3837@1|root,COG3837@2|Bacteria,1G5P0@1117|Cyanobacteria,1HHJM@1150|Oscillatoriales 1117|Cyanobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_2605922_1 1047013.AQSP01000128_gene418 2.095e-46 171.0 COG0739@1|root,COG0739@2|Bacteria 2|Bacteria M heme binding - - 3.4.24.75 ko:K08259 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 DYD1_k127_260605_3 279238.Saro_3541 3.938e-08 64.0 COG2010@1|root,COG2010@2|Bacteria,1N7I9@1224|Proteobacteria,2V1R3@28211|Alphaproteobacteria,2KBX4@204457|Sphingomonadales 204457|Sphingomonadales C Cytochrome c - - - - - - - - - - - - - DYD1_k127_260605_2 1122604.JONR01000007_gene2934 1.324e-22 108.0 COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,1MY07@1224|Proteobacteria 1224|Proteobacteria O COG3209 Rhs family protein - - - - - - - - - - - - - DYD1_k127_260605_0 1122604.JONR01000007_gene2936 4.267e-87 307.0 28P4Q@1|root,2ZBZV@2|Bacteria,1RA48@1224|Proteobacteria,1S347@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_260605_1 1134474.O59_002379 1.14e-29 125.0 COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S7A2@1236|Gammaproteobacteria 1236|Gammaproteobacteria D sister chromatid segregation - - - - - - - - - - - - - DYD1_k127_2607649_0 382245.ASA_1036 2.697e-115 383.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1Y3QN@135624|Aeromonadales 135624|Aeromonadales L Single-stranded-DNA-specific exonuclease recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD1_k127_2610994_2 1144275.COCOR_02389 3.995e-57 206.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD1_k127_2610994_1 448385.sce1759 1.847e-93 320.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales 28221|Deltaproteobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1,NUDIX DYD1_k127_2610994_0 697282.Mettu_2187 0.0 1068.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XEFJ@135618|Methylococcales 135618|Methylococcales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 DYD1_k127_2610994_3 870187.Thini_3154 1.461e-36 143.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,460M0@72273|Thiotrichales 72273|Thiotrichales D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 DYD1_k127_262019_4 234267.Acid_0968 8.483e-27 111.0 COG1012@1|root,COG1012@2|Bacteria,3Y3V5@57723|Acidobacteria 57723|Acidobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.28 ko:K00141,ko:K22187 ko00040,ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00040,map00622,map00623,map00627,map01100,map01120,map01220 M00537,M00538 R01293,R01419,R05289,R05663,R05664,R07667,R11768 RC00075,RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_262019_5 1123256.KB907927_gene1651 1.194e-13 75.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1X84S@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0125 (RnfH) family - - - ko:K09801 - - - - ko00000 - - - Ub-RnfH DYD1_k127_262019_3 592316.Pat9b_2990 1.799e-29 123.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,3VY9M@53335|Pantoea 1236|Gammaproteobacteria I Cyclase Dehydrase ratA GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - - - - - - - - - - Polyketide_cyc DYD1_k127_262019_0 713586.KB900536_gene3022 1.786e-85 291.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD1_k127_262019_1 572477.Alvin_2188 2.357e-64 224.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD1_k127_262019_2 1123517.JOMR01000001_gene1305 6.848e-61 213.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,460QE@72273|Thiotrichales 72273|Thiotrichales J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB DYD1_k127_2621106_0 85643.Tmz1t_1473 3.987e-137 459.0 COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales 206389|Rhodocyclales M Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,Patatin DYD1_k127_2625243_0 1280953.HOC_02291 7.919e-114 396.0 COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,2V4NX@28211|Alphaproteobacteria,43YZT@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 DYD1_k127_2625243_2 1408164.MOLA814_00003 3.402e-23 106.0 COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,2VIDQ@28216|Betaproteobacteria 28216|Betaproteobacteria C cytochrome c oxidase (Subunit II) coxM - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,Cytochrom_C DYD1_k127_2625243_1 1082933.MEA186_09775 6.224e-76 269.0 COG2041@1|root,COG2041@2|Bacteria,1NR5V@1224|Proteobacteria,2UQ6F@28211|Alphaproteobacteria,43R8Z@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Oxidoreductase molybdopterin binding domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb DYD1_k127_2637628_3 1131813.AQVT01000001_gene2598 3.065e-23 100.0 COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2TSFB@28211|Alphaproteobacteria,1JSFM@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1501) MA20_05265 - - - - - - - - - - - DUF1501 DYD1_k127_2637628_0 713586.KB900536_gene259 1.356e-116 383.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Aldo keto - - - - - - - - - - - - Aldo_ket_red,TAT_signal DYD1_k127_2637628_1 394221.Mmar10_1989 3.285e-99 334.0 COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2TRQ1@28211|Alphaproteobacteria,43Z9S@69657|Hyphomonadaceae 28211|Alphaproteobacteria V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - - DYD1_k127_2637628_5 453591.Igni_0759 3.143e-06 56.0 arCOG09415@1|root,arCOG09415@2157|Archaea,2XS53@28889|Crenarchaeota 28889|Crenarchaeota - - - - - - - - - - - - - - Reeler DYD1_k127_2637628_4 1499967.BAYZ01000013_gene6458 1.226e-13 79.0 COG3127@1|root,COG3127@2|Bacteria 2|Bacteria Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_2637628_2 1267535.KB906767_gene2392 7.456e-26 111.0 COG1846@1|root,COG1846@2|Bacteria,3Y861@57723|Acidobacteria 57723|Acidobacteria K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_34 DYD1_k127_2656066_3 1056820.KB900652_gene3227 1.88e-07 58.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,2PNCE@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S zinc-ribbon domain - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 DYD1_k127_2656066_2 1286106.MPL1_04327 7.326e-19 90.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,461ER@72273|Thiotrichales 72273|Thiotrichales KL Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters - - - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 DYD1_k127_2656066_0 1123253.AUBD01000013_gene926 7.722e-188 601.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1X3IH@135614|Xanthomonadales 135614|Xanthomonadales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS DYD1_k127_2656066_1 1249627.D779_4205 7.633e-170 542.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1WW3A@135613|Chromatiales 135613|Chromatiales F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N DYD1_k127_2656066_4 1123321.KB905836_gene2341 7.105e-05 46.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - - - - - - - - - - Amidohydro_1 DYD1_k127_2662657_2 987059.RBXJA2T_16907 2.875e-80 268.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,1KJX9@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N DYD1_k127_2662657_3 75379.Tint_2753 2.561e-52 188.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KKT3@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N DYD1_k127_2662657_0 247633.GP2143_04580 1.278e-194 624.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1J4MG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC GO:0003674,GO:0003824,GO:0004022,GO:0004024,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009636,GO:0009987,GO:0010033,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017001,GO:0017144,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046292,GO:0046294,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0051903,GO:0055114,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:0110095,GO:0110096,GO:1901575,GO:1901700,GO:1901701,GO:1990748 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_0393,iEC55989_1330.EC55989_0365,iECH74115_1262.ECH74115_0431,iECIAI1_1343.ECIAI1_0357,iECIAI39_1322.ECIAI39_0322,iECO103_1326.ECO103_0338,iECO111_1330.ECO111_0392,iECO26_1355.ECO26_0392,iECSE_1348.ECSE_0381,iECSP_1301.ECSP_0420,iECUMN_1333.ECUMN_0399,iECW_1372.ECW_m0434,iECs_1301.ECs0411,iEKO11_1354.EKO11_3486,iETEC_1333.ETEC_0412,iEcE24377_1341.EcE24377A_0381,iEcHS_1320.EcHS_A0421,iEcolC_1368.EcolC_3269,iG2583_1286.G2583_0469,iSSON_1240.SSON_0335,iSbBS512_1146.SbBS512_E0271,iUMNK88_1353.UMNK88_407,iWFL_1372.ECW_m0434,iZ_1308.Z0456 ADH_N,ADH_zinc_N DYD1_k127_2662657_1 713586.KB900536_gene740 2.303e-136 447.0 COG0294@1|root,COG0801@1|root,COG0294@2|Bacteria,COG0801@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind DYD1_k127_2662657_4 1283300.ATXB01000001_gene1602 5.946e-51 183.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XDNC@135618|Methylococcales 135618|Methylococcales EH synthase component I pabB - 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind DYD1_k127_26653_2 1340493.JNIF01000004_gene600 1.676e-36 145.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - - - - - - - - - - - PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5 DYD1_k127_26653_0 379066.GAU_2742 1.76e-268 852.0 COG0433@1|root,COG0433@2|Bacteria,1ZUJE@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Domain of unknown function DUF87 - - - - - - - - - - - - DUF87 DYD1_k127_26653_1 945713.IALB_1077 3.937e-45 166.0 COG1970@1|root,COG1970@2|Bacteria 2|Bacteria M mechanosensitive ion channel activity mscL GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL DYD1_k127_26653_3 1287276.X752_15530 3.511e-09 60.0 COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UFPQ@28211|Alphaproteobacteria,43M7Y@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin DYD1_k127_2666016_4 1286106.MPL1_07782 4.288e-22 96.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,45ZT0@72273|Thiotrichales 72273|Thiotrichales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG DYD1_k127_2666016_0 1278309.KB907101_gene782 2.203e-60 218.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1XJCZ@135619|Oceanospirillales 135619|Oceanospirillales F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin DYD1_k127_2666016_3 396588.Tgr7_1828 8.445e-34 146.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1WW0S@135613|Chromatiales 135613|Chromatiales L DNA polymerase III, delta' - - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C DYD1_k127_2666016_1 1123261.AXDW01000004_gene2877 1.598e-47 173.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1X6W7@135614|Xanthomonadales 135614|Xanthomonadales NU Pilus assembly protein PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ DYD1_k127_2666016_2 391615.ABSJ01000026_gene110 2.071e-43 162.0 COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria PT COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - Rhodanese,cNMP_binding DYD1_k127_2675681_0 314278.NB231_05806 1.682e-99 330.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1WWPA@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase - - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD DYD1_k127_2675681_1 1286106.MPL1_00507 9.153e-91 316.0 COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,45ZQW@72273|Thiotrichales 72273|Thiotrichales K TIGRFAM YihY family protein (not ribonuclease BN) - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB DYD1_k127_2675681_2 1163617.SCD_n02042 1.161e-07 53.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria 28216|Betaproteobacteria F Belongs to the SAICAR synthetase family purC GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt DYD1_k127_2688045_0 861299.J421_4151 9.475e-101 341.0 COG3182@1|root,COG3182@2|Bacteria,1ZUQI@142182|Gemmatimonadetes 142182|Gemmatimonadetes S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM DYD1_k127_2688045_1 1082931.KKY_123 2.613e-40 154.0 2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2688045_3 1247726.MIM_c16930 8.465e-08 64.0 COG4948@1|root,COG4948@2|Bacteria,1PK0G@1224|Proteobacteria,2W8C4@28216|Betaproteobacteria,3T6J4@506|Alcaligenaceae 28216|Betaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C DYD1_k127_2698034_0 187272.Mlg_0941 1.215e-274 854.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1WW7K@135613|Chromatiales 135613|Chromatiales T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_2698034_2 1209072.ALBT01000032_gene2119 9.36e-64 224.0 COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,1RQ8S@1236|Gammaproteobacteria 1236|Gammaproteobacteria O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA DYD1_k127_2698034_3 1121920.AUAU01000006_gene301 5.564e-38 149.0 2BYAB@1|root,32R2Z@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2698034_1 715451.ambt_12010 4.933e-68 246.0 2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2698034_4 1123400.KB904780_gene1794 1.988e-14 84.0 COG2995@1|root,COG2995@2|Bacteria,1NA1F@1224|Proteobacteria,1SERF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Paraquat-inducible protein A - - - - - - - - - - - - PqiA DYD1_k127_2700748_7 627192.SLG_09880 1.951e-14 81.0 28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_2700748_6 1088721.NSU_2830 1.173e-24 107.0 2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_2700748_3 237368.SCABRO_01389 1.616e-36 142.0 COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes 203682|Planctomycetes O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_2700748_4 1121937.AUHJ01000002_gene3414 7.768e-35 144.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,46557@72275|Alteromonadaceae 1236|Gammaproteobacteria T Universal stress protein - - - ko:K14055 - - - - ko00000 - - - Usp DYD1_k127_2700748_0 633149.Bresu_2122 8.456e-143 464.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Methionine synthase - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_2700748_2 365046.Rta_04620 2.852e-127 422.0 COG0715@1|root,COG0715@2|Bacteria,1RJQU@1224|Proteobacteria,2VVYG@28216|Betaproteobacteria 28216|Betaproteobacteria P Protein of unknown function (DUF3500) - - - - - - - - - - - - DUF3500 DYD1_k127_2700748_1 1403819.BATR01000102_gene3371 1.805e-131 434.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - DUF4976,Sulfatase DYD1_k127_2700748_5 240015.ACP_3525 5.38e-28 124.0 COG3182@1|root,COG3182@2|Bacteria,3Y2R7@57723|Acidobacteria,2JIBB@204432|Acidobacteriia 204432|Acidobacteriia S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM DYD1_k127_2700748_8 555793.WSK_1941 4.861e-13 77.0 28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_2751568_5 522306.CAP2UW1_2490 1.741e-48 179.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,1KQCU@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H Tetrapyrrole (Corrin/Porphyrin) Methylases cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase DYD1_k127_2751568_0 1026882.MAMP_01780 3.87e-164 521.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,460E7@72273|Thiotrichales 72273|Thiotrichales E Pyridoxal-phosphate dependent enzyme - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_2751568_4 1057002.KB905370_gene3782 6.455e-54 210.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TUKX@28211|Alphaproteobacteria,4BAF2@82115|Rhizobiaceae 28211|Alphaproteobacteria S Adenylate cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - - DYD1_k127_2751568_2 518766.Rmar_0511 6.218e-121 402.0 COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes 976|Bacteroidetes G Glucose Sorbosone dehydrogenase - - - - - - - - - - - - GSDH DYD1_k127_2751568_1 627192.SLG_31390 5.978e-128 430.0 COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT ankyrin repeat - - - ko:K15503 - - - - ko00000,ko01009,ko03400 - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5 DYD1_k127_2751568_3 627192.SLG_31400 2.675e-97 328.0 COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_2753974_3 357808.RoseRS_2742 3.483e-30 123.0 COG2957@1|root,COG2957@2|Bacteria,2GAHD@200795|Chloroflexi,37657@32061|Chloroflexia 32061|Chloroflexia E Belongs to the agmatine deiminase family - - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph DYD1_k127_2753974_4 1380390.JIAT01000013_gene64 1.754e-24 111.0 COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4CQ9B@84995|Rubrobacteria 84995|Rubrobacteria K Uncharacterized ACR, COG1678 - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 DYD1_k127_2753974_1 1537715.JQFJ01000002_gene881 5.019e-114 376.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U4X1@28211|Alphaproteobacteria,2K9G4@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_2753974_2 339670.Bamb_0824 1.027e-69 251.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VNEB@28216|Betaproteobacteria,1K4GV@119060|Burkholderiaceae 28216|Betaproteobacteria EGP Drug resistance transporter Bcr CflA subfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 DYD1_k127_2753974_0 398578.Daci_0103 2.931e-125 406.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VTUV@28216|Betaproteobacteria,4AET5@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B - - 1.13.11.16,1.13.11.8 ko:K04101,ko:K05713 ko00360,ko00362,ko00624,ko00627,ko01120,ko01220,map00360,map00362,map00624,map00627,map01120,map01220 M00545 R01632,R03550,R04280,R04376,R06788,R09565 RC00233,RC00387,RC00535,RC01140,RC01364,RC02567,RC02694 br01602,ko00000,ko00001,ko00002,ko01000 - - - LigB DYD1_k127_2753974_5 392499.Swit_4310 2.472e-18 85.0 2DPNC@1|root,32UMG@2|Bacteria,1N0XW@1224|Proteobacteria,2UVTT@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - - - - - - - - - - LigA DYD1_k127_2756485_0 861299.J421_5942 1.85e-129 423.0 COG0709@1|root,COG0709@2|Bacteria 2|Bacteria E selenide, water dikinase activity selD GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - iPC815.YPO2164,iSFV_1184.SFV_1453,iSF_1195.SF1459,iSFxv_1172.SFxv_1645,iS_1188.S1574 AIRS,AIRS_C DYD1_k127_2756485_1 1041146.ATZB01000034_gene559 1.385e-57 203.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,4BD23@82115|Rhizobiaceae 28211|Alphaproteobacteria E Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 DYD1_k127_2786072_0 1254432.SCE1572_28410 5.593e-70 246.0 COG4099@1|root,COG4099@2|Bacteria 2|Bacteria F phospholipase Carboxylesterase gbpD - - - - - - - - - - - Abhydrolase_2,Abhydrolase_8,Peptidase_S9 DYD1_k127_2786072_1 487316.BBNM01000005_gene299 4.526e-54 202.0 COG0583@1|root,COG0583@2|Bacteria,1Q8UG@1224|Proteobacteria,1S05A@1236|Gammaproteobacteria,3NKV9@468|Moraxellaceae 1236|Gammaproteobacteria K LysR substrate binding domain hcaR GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K05817 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD1_k127_2798255_0 555088.DealDRAFT_2281 2.676e-34 150.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,42JRM@68298|Syntrophomonadaceae 186801|Clostridia V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran DYD1_k127_2801196_1 105422.BBPM01000060_gene4257 1.564e-107 353.0 COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,2NNCT@228398|Streptacidiphilus 201174|Actinobacteria C Dehydrogenase E1 component acoA - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD1_k127_2801196_0 1245469.S58_09960 3.717e-195 614.0 COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria,3JXT1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 DYD1_k127_2811157_4 935261.JAGL01000004_gene864 3.17e-11 65.0 COG0179@1|root,COG0179@2|Bacteria,1NTUI@1224|Proteobacteria,2U2F5@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase DYD1_k127_2811157_2 935261.JAGL01000004_gene865 3.845e-31 130.0 2DT2T@1|root,33IFN@2|Bacteria 2|Bacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_4 DYD1_k127_2811157_3 935261.JAGL01000004_gene867 1.173e-24 107.0 COG3384@1|root,COG3384@2|Bacteria 2|Bacteria S 3-carboxyethylcatechol 2,3-dioxygenase activity - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA DYD1_k127_2811157_0 935261.JAGL01000004_gene868 2.969e-95 329.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,43J3C@69277|Phyllobacteriaceae 1224|Proteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB DYD1_k127_2811157_1 1121939.L861_10245 2.641e-32 127.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1XH63@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the GMC oxidoreductase family - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N DYD1_k127_2815150_1 357804.Ping_1366 1.378e-108 356.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,2QHK5@267894|Psychromonadaceae 1236|Gammaproteobacteria P Na Ca antiporter, CaCA family - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD1_k127_2815150_2 1150398.JIBJ01000006_gene3587 2.079e-48 181.0 COG0637@1|root,COG0637@2|Bacteria,2GMIQ@201174|Actinobacteria 201174|Actinobacteria Q hydrolase - - - - - - - - - - - - HAD_2 DYD1_k127_2815150_0 1101191.KI912577_gene3112 1.199e-223 703.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,1JRY8@119045|Methylobacteriaceae 28211|Alphaproteobacteria F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N DYD1_k127_2815150_3 929562.Emtol_2151 2.342e-24 106.0 COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,47KUR@768503|Cytophagia 976|Bacteroidetes G Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP DYD1_k127_2825492_2 1122927.KB895415_gene4653 1.296e-40 154.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,26SJF@186822|Paenibacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 DYD1_k127_2825492_1 105559.Nwat_2316 8.902e-47 178.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales 135613|Chromatiales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N DYD1_k127_2825492_0 1151116.Q7S_17275 1.217e-90 305.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,3FEYU@34037|Rahnella 1236|Gammaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 PdxJ DYD1_k127_2825492_3 105559.Nwat_2314 3.091e-19 96.0 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1WZIU@135613|Chromatiales 135613|Chromatiales I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS DYD1_k127_283476_7 314278.NB231_05566 1.15e-09 60.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales 135613|Chromatiales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin DYD1_k127_283476_0 396588.Tgr7_0774 7.964e-201 633.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales 135613|Chromatiales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA DYD1_k127_283476_5 95619.PM1_0206655 1.79e-37 151.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 DYD1_k127_283476_4 1335757.SPICUR_07625 8.952e-88 302.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales 135613|Chromatiales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C DYD1_k127_283476_1 1049564.TevJSym_aj00290 5.647e-176 567.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1J4RF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_283476_2 396588.Tgr7_0769 2.04e-116 385.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1WWB9@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 DYD1_k127_283476_3 396588.Tgr7_0768 6.32e-101 343.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1WWCK@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE DYD1_k127_283476_6 637389.Acaty_c2505 3.799e-10 61.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,2NC0M@225057|Acidithiobacillales 225057|Acidithiobacillales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M DYD1_k127_2836385_7 1191523.MROS_2770 9.982e-16 87.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding usp-3 - - - - - - - - - - - Usp DYD1_k127_2836385_6 1174684.EBMC1_00415 4.501e-19 100.0 COG2128@1|root,COG2128@2|Bacteria,1MVWP@1224|Proteobacteria,2VGCN@28211|Alphaproteobacteria,2K62F@204457|Sphingomonadales 204457|Sphingomonadales S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD1_k127_2836385_4 330084.JNYZ01000029_gene137 1.388e-29 132.0 COG2128@1|root,COG2128@2|Bacteria,2IAT6@201174|Actinobacteria,4EEYQ@85010|Pseudonocardiales 201174|Actinobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD1_k127_2836385_0 46429.BV95_03401 8.623e-106 362.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,2K23S@204457|Sphingomonadales 204457|Sphingomonadales CH FAD binding domain pcpB - 1.14.13.127,1.14.13.50 ko:K03391,ko:K05712 ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220 M00545 R03982,R06786,R06787,R07779 RC00236,RC01932 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD1_k127_2836385_2 794846.AJQU01000114_gene4891 3.104e-56 203.0 28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2TU05@28211|Alphaproteobacteria,4BC3I@82115|Rhizobiaceae 28211|Alphaproteobacteria - - MA20_08580 - - - - - - - - - - - Endostatin DYD1_k127_2836385_3 1168034.FH5T_02255 2.366e-49 188.0 COG1506@1|root,COG1506@2|Bacteria,4PN2U@976|Bacteroidetes 976|Bacteroidetes E peptidase - - - - - - - - - - - - - DYD1_k127_2836385_5 247633.GP2143_13086 1.354e-19 95.0 2FIXR@1|root,312JV@2|Bacteria,1NBAI@1224|Proteobacteria 1224|Proteobacteria S Cytochrome C' - - - - - - - - - - - - Cytochrom_C_2 DYD1_k127_2836385_1 1123053.AUDG01000028_gene1307 1.719e-101 341.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1WX3Q@135613|Chromatiales 135613|Chromatiales K Transcriptional regulator cysB - - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD1_k127_2836385_8 265072.Mfla_0652 9.884e-06 51.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,2KKMV@206350|Nitrosomonadales 206350|Nitrosomonadales H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase DYD1_k127_2836407_0 1173263.Syn7502_03154 2.867e-87 290.0 COG0426@1|root,COG0426@2|Bacteria,1GC47@1117|Cyanobacteria,1H324@1129|Synechococcus 1117|Cyanobacteria C domain, Protein - - - - - - - - - - - - - DYD1_k127_2836407_1 697282.Mettu_0315 8.802e-33 133.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1XFP2@135618|Methylococcales 135618|Methylococcales U Type IV minor pilin ComP, DNA uptake sequence receptor - - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl DYD1_k127_2846768_1 396588.Tgr7_3261 4.873e-63 222.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 DYD1_k127_2846768_0 349124.Hhal_1215 1.548e-162 534.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WW4B@135613|Chromatiales 135613|Chromatiales T response regulator glnG - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_2854383_1 586413.CCDL010000001_gene1383 5.862e-23 100.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,23JP9@182709|Oceanobacillus 91061|Bacilli EG GntP family permease gntU - - ko:K03299,ko:K06156 - - - - ko00000,ko02000 2.A.8,2.A.8.1.8 - - GntP_permease DYD1_k127_2854383_0 218284.CCDN010000002_gene2143 1.524e-128 420.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,1ZAYI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases gntU - - ko:K03299,ko:K06156 - - - - ko00000,ko02000 2.A.8,2.A.8.1.8 - - GntP_permease DYD1_k127_2854383_2 1415780.JPOG01000001_gene559 6.818e-13 69.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1XCK0@135614|Xanthomonadales 135614|Xanthomonadales O Hsp20/alpha crystallin family - - - - - - - - - - - - HSP20 DYD1_k127_2856631_4 349124.Hhal_1465 2.218e-20 91.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales 135613|Chromatiales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD1_k127_2856631_0 713586.KB900536_gene139 6.954e-108 354.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1WX9S@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD1_k127_2856631_2 519989.ECTPHS_08468 1.557e-71 245.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1WY5S@135613|Chromatiales 135613|Chromatiales J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF DYD1_k127_2856631_1 243233.MCA0571 3.498e-83 283.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1XEM4@135618|Methylococcales 135618|Methylococcales H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD1_k127_2856631_3 1504981.KO116_0466 1.301e-23 111.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1XJNR@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 DYD1_k127_2867130_2 1388763.O165_007015 6.728e-34 143.0 COG3391@1|root,COG3391@2|Bacteria,1PGT6@1224|Proteobacteria,1RXFC@1236|Gammaproteobacteria,1YZCY@136845|Pseudomonas putida group 1236|Gammaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - - DYD1_k127_2867130_0 1173020.Cha6605_0439 5.316e-116 391.0 COG2303@1|root,COG2303@2|Bacteria,1G2FA@1117|Cyanobacteria 1117|Cyanobacteria E Glucose-methanol-choline (GMC) oxidoreductase NAD binding site cetA - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N DYD1_k127_2867130_1 285535.JOEY01000112_gene2157 9.535e-57 212.0 COG0111@1|root,COG0111@2|Bacteria,2IEY1@201174|Actinobacteria 201174|Actinobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_2867130_5 1396418.BATQ01000151_gene2324 4.14e-11 73.0 COG1442@1|root,COG1442@2|Bacteria,46W1U@74201|Verrucomicrobia 74201|Verrucomicrobia M glycosyl transferase family 8 - - - - - - - - - - - - - DYD1_k127_2867130_4 1340493.JNIF01000003_gene2122 5.03e-26 112.0 2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - DYD1_k127_2867130_3 136993.KB900627_gene392 1.85e-27 119.0 28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2870347_0 880073.Calab_3226 1.305e-189 599.0 COG0495@1|root,COG0495@2|Bacteria,2NNQH@2323|unclassified Bacteria 2|Bacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 DYD1_k127_2870347_4 396588.Tgr7_2278 1.142e-15 90.0 COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,1WY80@135613|Chromatiales 135613|Chromatiales M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE DYD1_k127_2870347_3 396588.Tgr7_2693 6.447e-51 188.0 2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,1WYF1@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD1_k127_2870347_2 344747.PM8797T_09624 6.585e-72 246.0 COG0139@1|root,COG0139@2|Bacteria,2J07K@203682|Planctomycetes 203682|Planctomycetes E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19 ko:K01496 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04037 RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH DYD1_k127_2870347_1 1123257.AUFV01000008_gene674 1.529e-147 474.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1X2ZK@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e DYD1_k127_2876390_0 1415779.JOMH01000001_gene76 3.193e-121 402.0 COG1914@1|root,COG1914@2|Bacteria 2|Bacteria P metal ion transmembrane transporter activity mntH - - - - - - - - - - - Nramp DYD1_k127_2876390_1 627192.SLG_26430 5.86e-59 212.0 2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_2884023_0 653733.Selin_2107 2.566e-101 335.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion hflC - - - - - - - - - - - Band_7 DYD1_k127_2884023_1 1049564.TevJSym_be00360 6.187e-81 286.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1J5VV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction histidine kinase phoQ - 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,PhoQ_Sensor DYD1_k127_2884023_2 1234364.AMSF01000010_gene561 3.827e-46 172.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1X2XT@135614|Xanthomonadales 135614|Xanthomonadales KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K07660 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_2891836_1 1122176.KB903535_gene1887 8.137e-36 142.0 COG3206@1|root,COG5184@1|root,COG3206@2|Bacteria,COG5184@2|Bacteria,4NH33@976|Bacteroidetes 976|Bacteroidetes M regulator of chromosome condensation, RCC1 - - - - - - - - - - - - - DYD1_k127_2891836_0 1042377.AFPJ01000036_gene1223 2.024e-69 247.0 COG0457@1|root,COG0457@2|Bacteria 1042377.AFPJ01000036_gene1223|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_2892148_0 396588.Tgr7_0798 5.662e-84 287.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1WVXU@135613|Chromatiales 135613|Chromatiales H Belongs to the NadC ModD family - - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N DYD1_k127_2892148_3 323261.Noc_1372 1.822e-58 210.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1X0P1@135613|Chromatiales 135613|Chromatiales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N DYD1_k127_2892148_4 697282.Mettu_2882 6.647e-42 156.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1XFF2@135618|Methylococcales 135618|Methylococcales C Belongs to the glutaredoxin family. Monothiol subfamily - - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin DYD1_k127_2892148_2 1033802.SSPSH_001221 5.397e-77 267.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T DYD1_k127_2892148_1 745411.B3C1_05622 1.235e-78 269.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1J4XV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides - - - - - - - - - - - - Peptidase_M17 DYD1_k127_2919228_0 1122604.JONR01000001_gene1738 6.349e-132 426.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales 135614|Xanthomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 DYD1_k127_2919228_2 1121013.P873_06635 7.459e-39 153.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,1X3T9@135614|Xanthomonadales 135614|Xanthomonadales L DNA mismatch repair protein MutT - - - - - - - - - - - - DUF1289,NUDIX DYD1_k127_2919228_1 1177179.A11A3_11237 2.421e-75 264.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1XI3P@135619|Oceanospirillales 135619|Oceanospirillales S pyrophosphohydrolase mazG - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG DYD1_k127_2919228_3 1123253.AUBD01000005_gene273 3.709e-08 61.0 COG3134@1|root,COG3134@2|Bacteria,1NN8B@1224|Proteobacteria,1SHVC@1236|Gammaproteobacteria,1X7TC@135614|Xanthomonadales 135614|Xanthomonadales S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti DYD1_k127_2920157_3 627192.SLG_04410 2.824e-34 135.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K1V6@204457|Sphingomonadales 204457|Sphingomonadales G PQQ-like domain - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD1_k127_2920157_4 861299.J421_2050 2.791e-27 115.0 COG3695@1|root,COG3695@2|Bacteria 2|Bacteria L enzyme binding ogt - 2.1.1.63 ko:K00567,ko:K07443 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,YjbR DYD1_k127_2920157_2 1121013.P873_09545 5.475e-73 252.0 COG4912@1|root,COG4912@2|Bacteria,1RGNQ@1224|Proteobacteria,1S4I1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation DYD1_k127_2920157_6 113395.AXAI01000010_gene2219 8.215e-06 55.0 2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,3K43P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2920157_5 257310.BB2899 6.735e-22 99.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,2VU8X@28216|Betaproteobacteria,3T47B@506|Alcaligenaceae 28216|Betaproteobacteria S Protein of unknown function (DUF423) ygdD - - - - - - - - - - - DUF423 DYD1_k127_2920157_1 1112217.PPL19_13920 6.23e-104 348.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Dala_Dala_lig_C,Dala_Dala_lig_N DYD1_k127_2920157_0 136993.KB900626_gene3898 1.415e-110 373.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,36X8N@31993|Methylocystaceae 28211|Alphaproteobacteria L DEAD/H associated lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C DYD1_k127_2933625_2 1128912.GMES_2945 9.44e-26 111.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,464XD@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0035 DapB_C,DapB_N DYD1_k127_2933625_1 1121937.AUHJ01000006_gene2453 2.528e-150 483.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,464JW@72275|Alteromonadaceae 1236|Gammaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0006457,GO:0008150,GO:0009987 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD1_k127_2933625_0 713586.KB900536_gene3031 4.487e-278 863.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales 135613|Chromatiales O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD1_k127_2957436_0 243090.RB2121 1.33e-83 281.0 COG2326@1|root,COG2326@2|Bacteria,2IYWN@203682|Planctomycetes 203682|Planctomycetes S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 DYD1_k127_2957436_1 1472418.BBJC01000004_gene1788 3.99e-50 198.0 2CBAE@1|root,31814@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2957436_2 234267.Acid_4171 1.189e-10 66.0 COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria 57723|Acidobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_2959522_0 998674.ATTE01000001_gene497 4.667e-182 582.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,4608B@72273|Thiotrichales 72273|Thiotrichales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom DYD1_k127_2959522_2 1335757.SPICUR_00240 7.755e-51 186.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1WY2S@135613|Chromatiales 135613|Chromatiales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC DYD1_k127_2959522_1 1453501.JELR01000002_gene1108 3.058e-166 559.0 COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,4683H@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase inhibitor I9 - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8 DYD1_k127_298077_2 765911.Thivi_3675 6.184e-143 462.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales 135613|Chromatiales E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C DYD1_k127_298077_10 1123073.KB899242_gene1475 2.906e-37 155.0 2DM5E@1|root,31SVN@2|Bacteria,1MYKR@1224|Proteobacteria,1SBG8@1236|Gammaproteobacteria,1X91Z@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 DYD1_k127_298077_1 1123073.KB899242_gene1476 5.37e-151 498.0 COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,1X4RC@135614|Xanthomonadales 135614|Xanthomonadales N transport system involved in gliding motility, auxiliary component - - - - - - - - - - - - ABC_transp_aux DYD1_k127_298077_6 1123073.KB899242_gene1477 2.253e-102 343.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales 135614|Xanthomonadales S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 DYD1_k127_298077_5 1123073.KB899242_gene1478 1.164e-109 363.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1X3JY@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_298077_4 1265313.HRUBRA_00272 2.899e-127 415.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1J5A8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 DYD1_k127_298077_0 2340.JV46_14610 4.111e-171 547.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 DYD1_k127_298077_8 65393.PCC7424_1898 2.214e-72 253.0 COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,3KHH2@43988|Cyanothece 1117|Cyanobacteria Q dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_298077_3 261292.Nit79A3_0718 2.328e-131 440.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2WGNM@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - ko:K06714,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022,ko03000 - - - HTH_8,PAS_4,Sigma54_activat DYD1_k127_298077_12 222534.KB893751_gene4126 2.275e-07 63.0 COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4ERVM@85013|Frankiales 201174|Actinobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF DYD1_k127_298077_11 1123257.AUFV01000003_gene1024 1.691e-07 62.0 COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1X7KU@135614|Xanthomonadales 135614|Xanthomonadales T Bacterial SH3 domain homologues - - - - - - - - - - - - SH3_3 DYD1_k127_298077_9 340.xcc-b100_2673 8.196e-52 190.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1X631@135614|Xanthomonadales 135614|Xanthomonadales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct DYD1_k127_298077_7 1121013.P873_02290 2.616e-99 334.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,1X3VH@135614|Xanthomonadales 135614|Xanthomonadales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb DYD1_k127_3007965_0 1049564.TevJSym_ad01620 4.215e-239 756.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1J4UF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - - - - - - - - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU DYD1_k127_3007965_1 1121937.AUHJ01000010_gene1749 3.975e-34 135.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria,467JH@72275|Alteromonadaceae 1236|Gammaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC DYD1_k127_3009415_1 754436.JCM19237_2629 2.977e-83 281.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XSC8@135623|Vibrionales 135623|Vibrionales V Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD1_k127_3009415_4 1117647.M5M_11220 8.603e-08 61.0 29WW8@1|root,30IHW@2|Bacteria,1QXWS@1224|Proteobacteria,1T3ID@1236|Gammaproteobacteria,1J7AN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Type II secretion system protein B - - - ko:K02451 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - T2SSB DYD1_k127_3009415_0 1415780.JPOG01000001_gene1137 1.513e-112 383.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1X4ZI@135614|Xanthomonadales 135614|Xanthomonadales U AAA domain - - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 DYD1_k127_3009415_3 1333998.M2A_0286 5.649e-44 165.0 2CD0I@1|root,32RWS@2|Bacteria,1N0MC@1224|Proteobacteria,2U9CM@28211|Alphaproteobacteria,4BSAQ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF4399) - - - - - - - - - - - - DUF4399 DYD1_k127_3009415_2 1123073.KB899241_gene1957 1.83e-61 222.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1X333@135614|Xanthomonadales 135614|Xanthomonadales I converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974 DYD1_k127_3010013_0 187272.Mlg_2624 1.739e-61 226.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 DYD1_k127_3010013_1 314278.NB231_11619 5.284e-28 121.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,1WYAZ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 DYD1_k127_3013165_3 314278.NB231_03175 4.205e-67 241.0 COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1WWFF@135613|Chromatiales 135613|Chromatiales V ABC-type transport system, involved in lipoprotein release, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_3013165_2 243231.GSU2186 1.817e-92 320.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,42Q9D@68525|delta/epsilon subdivisions,2WK21@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Lipocalin-like domain - - - - - - - - - - - - CrtC,Lipocalin_9 DYD1_k127_3013165_7 582899.Hden_2289 2.297e-43 167.0 COG3485@1|root,COG3485@2|Bacteria,1MV6K@1224|Proteobacteria,2TUS4@28211|Alphaproteobacteria,3N7RX@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria Q Dioxygenase - - - - - - - - - - - - Dioxygenase_C DYD1_k127_3013165_10 555793.WSK_2874 7.485e-07 61.0 2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_3013165_8 555793.WSK_4047 1.345e-12 79.0 28NHI@1|root,2ZBJA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3013165_0 1123072.AUDH01000007_gene1128 5.829e-141 455.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2JZPA@204441|Rhodospirillales 204441|Rhodospirillales E Cobalamin-independent synthase, Catalytic domain - - - - - - - - - - - - Meth_synt_2 DYD1_k127_3013165_9 67267.JNXT01000053_gene2916 5.149e-10 61.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase DYD1_k127_3013165_6 1380394.JADL01000010_gene4153 1.825e-44 164.0 COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TTXE@28211|Alphaproteobacteria,2JY2P@204441|Rhodospirillales 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K08234 - - - - ko00000 - - - Glyoxalase DYD1_k127_3013165_1 1005048.CFU_3220 3.578e-128 424.0 COG2271@1|root,COG2271@2|Bacteria,1P24P@1224|Proteobacteria,2VIKS@28216|Betaproteobacteria,4791C@75682|Oxalobacteraceae 28216|Betaproteobacteria G Sugar (and other) transporter pcaK - - ko:K08195 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,MFS_4 DYD1_k127_3013165_4 438753.AZC_0423 1.046e-52 195.0 COG3531@1|root,COG3531@2|Bacteria,1RA76@1224|Proteobacteria,2U6DU@28211|Alphaproteobacteria 28211|Alphaproteobacteria O DSBA-like thioredoxin domain - - - ko:K07396 - - - - ko00000 - - - DSBA DYD1_k127_3013165_5 203122.Sde_2997 5.387e-48 178.0 COG1858@1|root,COG2931@1|root,COG1858@2|Bacteria,COG2931@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,465BG@72275|Alteromonadaceae 1236|Gammaproteobacteria P Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - CCP_MauG,UnbV_ASPIC,VCBS DYD1_k127_3020277_6 566466.NOR53_3138 0.0007745 42.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1J955@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX DYD1_k127_3020277_1 713586.KB900536_gene1801 6.466e-107 354.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1WWRE@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 DYD1_k127_3020277_3 1211114.ALIP01000121_gene1172 5.588e-70 247.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1X4JP@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_YMGG,OmpA DYD1_k127_3020277_5 1453500.AT05_01855 2.903e-18 91.0 COG4539@1|root,COG4539@2|Bacteria,4NQIX@976|Bacteroidetes,1I2QB@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF962) - - - - - - - - - - - - DUF962 DYD1_k127_3020277_2 1049564.TevJSym_ab01370 1.554e-88 297.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,1J5UF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain chvI GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K02483,ko:K07663 ko02020,map02020 M00449 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_3020277_4 1120956.JHZK01000003_gene334 4.806e-56 207.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria,1JNU7@119043|Rhodobiaceae 28211|Alphaproteobacteria EG EamA-like transporter family - - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA DYD1_k127_3020277_0 595460.RRSWK_02267 0.0 1137.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2IXKD@203682|Planctomycetes 203682|Planctomycetes E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase DYD1_k127_3021606_1 225849.swp_0883 6.303e-16 87.0 COG3713@1|root,COG3713@2|Bacteria,1PUK9@1224|Proteobacteria,1TBET@1236|Gammaproteobacteria,2Q9E9@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM MltA-interacting MipA family protein - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA DYD1_k127_3021606_2 1385517.N800_09005 1.278e-09 66.0 COG3637@1|root,COG3637@2|Bacteria,1N3BJ@1224|Proteobacteria,1SFEZ@1236|Gammaproteobacteria,1X923@135614|Xanthomonadales 135614|Xanthomonadales M OmpA-like transmembrane domain - - - - - - - - - - - - OMP_b-brl DYD1_k127_3021606_0 77586.LPERR03G21690.1 8.498e-76 267.0 COG3491@1|root,KOG0143@2759|Eukaryota,37JYU@33090|Viridiplantae,3G8XN@35493|Streptophyta,3KUPH@4447|Liliopsida,3IE5T@38820|Poales 35493|Streptophyta Q Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N DYD1_k127_3026320_0 1469245.JFBG01000019_gene1125 1.445e-115 377.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales 135613|Chromatiales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS DYD1_k127_3026320_1 472759.Nhal_2800 5.73e-75 271.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1WWQ1@135613|Chromatiales 135613|Chromatiales H Belongs to the ribF family - - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase DYD1_k127_3026320_2 1335757.SPICUR_07520 1.287e-36 145.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales 135613|Chromatiales S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN DYD1_k127_3042371_7 396595.TK90_1971 2.73e-59 214.0 COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales 135613|Chromatiales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR DYD1_k127_3042371_5 754476.Q7A_2831 1.346e-76 280.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,4608W@72273|Thiotrichales 72273|Thiotrichales M Lytic murein transglycosylase B - - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 DYD1_k127_3042371_4 396588.Tgr7_2710 5.362e-120 400.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE DYD1_k127_3042371_2 1049564.TevJSym_ao00720 1.948e-168 549.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1J4EU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall mrdA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604 PBP_dimer,Transpeptidase DYD1_k127_3042371_8 545276.KB898725_gene828 8.804e-28 118.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales 135613|Chromatiales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD DYD1_k127_3042371_6 857087.Metme_1061 1.196e-61 223.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1XECP@135618|Methylococcales 135618|Methylococcales M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC DYD1_k127_3042371_1 1260251.SPISAL_07125 5.425e-177 559.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1WW91@135613|Chromatiales 135613|Chromatiales D TIGRFAM Cell shape determining protein MreB Mrl - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD1_k127_3042371_9 1415754.JQMK01000012_gene1204 3.579e-24 105.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,467YW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln DYD1_k127_3042371_0 765911.Thivi_3824 5.293e-205 647.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1WWC9@135613|Chromatiales 135613|Chromatiales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD1_k127_3042371_3 686340.Metal_0758 7.525e-126 406.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1XE06@135618|Methylococcales 135618|Methylococcales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey DYD1_k127_3055729_1 1042375.AFPL01000026_gene3736 2.882e-22 99.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,464B7@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans DYD1_k127_3055729_0 1469245.JFBG01000077_gene318 8.642e-172 547.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1WW6D@135613|Chromatiales 135613|Chromatiales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C DYD1_k127_3075443_1 1123253.AUBD01000010_gene2149 1.408e-19 90.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1X32P@135614|Xanthomonadales 135614|Xanthomonadales E aminotransferase - - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_3075443_0 1304883.KI912532_gene382 2.635e-75 282.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QU90@1224|Proteobacteria,2VHNR@28216|Betaproteobacteria 28216|Betaproteobacteria L RecB family exonuclease - - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - PDDEXK_1 DYD1_k127_3075443_2 1121918.ARWE01000001_gene1229 3.027e-14 75.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,43S3Q@69541|Desulfuromonadales 28221|Deltaproteobacteria L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C DYD1_k127_308698_0 396588.Tgr7_3156 8.121e-83 289.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales 135613|Chromatiales G PFAM Glucose Sorbosone dehydrogenase - - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH DYD1_k127_308698_1 1278309.KB907101_gene341 2.937e-36 139.0 COG3384@1|root,COG3384@2|Bacteria,1RIBC@1224|Proteobacteria,1SYBG@1236|Gammaproteobacteria,1XPM7@135619|Oceanospirillales 135619|Oceanospirillales S PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA DYD1_k127_3105252_2 1500894.JQNN01000001_gene4213 3.124e-19 96.0 2CJVH@1|root,2Z82D@2|Bacteria,1MX2M@1224|Proteobacteria 1224|Proteobacteria - - MA20_19455 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - DYD1_k127_3105252_1 1415756.JQMY01000001_gene735 1.342e-101 340.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U15G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S metal-dependent hydrolase of the TIM-barrel fold - - 4.1.1.103,4.1.1.46 ko:K07045,ko:K14333,ko:K15063,ko:K20941 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R09278,R11353 RC00390,RC00569 ko00000,ko00001,ko01000 - - - Amidohydro_2 DYD1_k127_3105252_0 935840.JAEQ01000003_gene279 1.701e-185 589.0 COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Aminomethyltransferase folate-binding domain - - 2.1.1.341 ko:K15066 ko00627,ko01120,map00627,map01120 - R09271,R10136 RC00113,RC00392 ko00000,ko00001,ko01000 - - - GCV_T,GCV_T_C DYD1_k127_3106459_1 713586.KB900536_gene2827 9.906e-37 143.0 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin DYD1_k127_3106459_0 504472.Slin_1529 9.084e-99 342.0 COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,47MRG@768503|Cytophagia 976|Bacteroidetes I Carboxylesterase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase DYD1_k127_3106459_2 247633.GP2143_17796 3.256e-32 136.0 28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_311479_1 189753.AXAS01000036_gene7766 3.187e-60 226.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JWM7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Periplasmic sensor domain found in signal transduction proteins - - - - - - - - - - - - CHASE5,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_311479_0 519989.ECTPHS_03592 4.406e-192 628.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales 135613|Chromatiales Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX DYD1_k127_311479_2 247633.GP2143_15821 7.799e-38 153.0 2BKN5@1|root,32F3J@2|Bacteria,1RIMC@1224|Proteobacteria,1S6Q3@1236|Gammaproteobacteria,1J7D1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp DYD1_k127_3132851_1 1122201.AUAZ01000019_gene1755 1.355e-112 367.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,464HF@72275|Alteromonadaceae 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB DYD1_k127_3132851_0 234267.Acid_5827 3.908e-167 546.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_3142555_1 87626.PTD2_18165 1.406e-28 116.0 2C7FC@1|root,32S1T@2|Bacteria,1N1DJ@1224|Proteobacteria,1S96F@1236|Gammaproteobacteria,2Q50J@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3142555_0 627192.SLG_12120 5.877e-118 404.0 2ED7G@1|root,32HXH@2|Bacteria,1NR36@1224|Proteobacteria,2UQ2U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_4 DYD1_k127_3142555_3 1033736.CAHK01000022_gene681 6.982e-09 64.0 COG4319@1|root,COG4319@2|Bacteria,2IFX9@201174|Actinobacteria 201174|Actinobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_4 DYD1_k127_3142555_2 1209072.ALBT01000032_gene2123 2.896e-12 75.0 2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_3156214_5 326442.PSHAa1026 5.728e-20 96.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,2PZN9@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase DYD1_k127_3156214_3 1158182.KB905023_gene1269 1.357e-28 119.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1WYQV@135613|Chromatiales 135613|Chromatiales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD1_k127_3156214_1 395493.BegalDRAFT_1129 3.445e-58 213.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,460SF@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD1_k127_3156214_0 1112217.PPL19_06395 5.406e-77 269.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria 1236|Gammaproteobacteria L dna polymerase III delta subunit holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta DYD1_k127_3156214_6 187272.Mlg_0273 3.501e-19 89.0 COG2835@1|root,COG2835@2|Bacteria,1P6IM@1224|Proteobacteria,1SV7D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Trm112p-like protein - - - - - - - - - - - - Trm112p DYD1_k127_3156214_4 243365.CV_4405 2.713e-28 117.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KS03@206351|Neisseriales 206351|Neisseriales S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic DYD1_k127_3156214_2 1122604.JONR01000020_gene514 8.415e-41 156.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1X2ZK@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e DYD1_k127_3158763_1 530564.Psta_2447 5.614e-69 243.0 COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase DYD1_k127_3158763_0 158500.BV97_04548 1.259e-79 282.0 COG1231@1|root,COG1231@2|Bacteria,1RA9M@1224|Proteobacteria,2TTDV@28211|Alphaproteobacteria,2K25J@204457|Sphingomonadales 204457|Sphingomonadales E Flavin containing amine oxidoreductase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase DYD1_k127_3161637_0 1234364.AMSF01000015_gene3100 1.791e-152 496.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1X4FN@135614|Xanthomonadales 135614|Xanthomonadales G Glucose dehydrogenase - - - - - - - - - - - - PQQ,PQQ_2 DYD1_k127_3161637_1 1045855.DSC_15215 2.566e-37 145.0 COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,1X64J@135614|Xanthomonadales 135614|Xanthomonadales I Acyltransferase - - - - - - - - - - - - Acyltransferase DYD1_k127_3187711_2 323261.Noc_1319 1.67e-14 85.0 COG0775@1|root,COG0775@2|Bacteria,1PETT@1224|Proteobacteria 1224|Proteobacteria F PFAM purine or other phosphorylase, family 1 MA20_16045 - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 DYD1_k127_3187711_0 105559.Nwat_1203 7.404e-120 396.0 COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,1RS93@1236|Gammaproteobacteria,1X0KC@135613|Chromatiales 135613|Chromatiales I Squalene phytoene synthase - - 2.5.1.21 ko:K00801 ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130 - R00702,R02872,R06223 RC00362,RC00796,RC02839 ko00000,ko00001,ko01000,ko01006 - - - SQS_PSY DYD1_k127_3187711_1 396588.Tgr7_0833 6.277e-79 274.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt DYD1_k127_3190450_6 1177181.T9A_00649 6.358e-26 112.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XHV3@135619|Oceanospirillales 135619|Oceanospirillales J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT DYD1_k127_3190450_5 1286106.MPL1_04175 4.035e-33 132.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,4616D@72273|Thiotrichales 72273|Thiotrichales J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq DYD1_k127_3190450_1 1255043.TVNIR_2776 1.423e-133 437.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1WVYW@135613|Chromatiales 135613|Chromatiales S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 DYD1_k127_3190450_3 396588.Tgr7_0899 6.379e-100 340.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1WWWJ@135613|Chromatiales 135613|Chromatiales O HflC and HflK could encode or regulate a protease - - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N DYD1_k127_3190450_4 159087.Daro_2977 2.539e-84 288.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,2KUAU@206389|Rhodocyclales 206389|Rhodocyclales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 DYD1_k127_3190450_7 1123504.JQKD01000031_gene4568 2.669e-11 65.0 COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,4AFHA@80864|Comamonadaceae 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2065) - - - ko:K09937 - - - - ko00000 - - - DUF2065 DYD1_k127_3190450_0 870187.Thini_0770 1.405e-176 563.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,45ZQU@72273|Thiotrichales 72273|Thiotrichales F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt DYD1_k127_3190450_9 1304275.C41B8_13990 2.259e-05 49.0 COG1918@1|root,COG1918@2|Bacteria,1NASN@1224|Proteobacteria,1SFGS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P FeoA - - - - - - - - - - - - FeoA DYD1_k127_3190450_2 518766.Rmar_2567 2.881e-103 352.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate DYD1_k127_3190450_8 1406840.Q763_11310 5.819e-07 55.0 COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,1HX6I@117743|Flavobacteriia,2NTMV@237|Flavobacterium 976|Bacteroidetes E Cytochrome C4 - - - - - - - - - - - - DAHP_synth_1 DYD1_k127_3190834_0 1088721.NSU_3284 1.144e-83 303.0 COG1629@1|root,COG4772@1|root,COG4771@2|Bacteria,COG4772@2|Bacteria,1MVFB@1224|Proteobacteria,2U2UJ@28211|Alphaproteobacteria,2KEDN@204457|Sphingomonadales 204457|Sphingomonadales P TonB-dependent receptor plug - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_3206960_1 187272.Mlg_0716 3.759e-48 184.0 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria,1WZCT@135613|Chromatiales 135613|Chromatiales EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_3206960_0 1122613.ATUP01000001_gene2020 1.336e-96 328.0 COG0627@1|root,COG0627@2|Bacteria,1QIRQ@1224|Proteobacteria,2TUU5@28211|Alphaproteobacteria,43Z22@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Putative esterase - - - - - - - - - - - - Esterase DYD1_k127_3206960_2 935863.AWZR01000001_gene1890 1.122e-07 54.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales 135614|Xanthomonadales IQ Activates fatty acids by binding to coenzyme A - - - - - - - - - - - - AMP-binding,AMP-binding_C,Acyltransferase DYD1_k127_322298_1 379066.GAU_2306 8.919e-70 241.0 COG0534@1|root,COG0534@2|Bacteria,1ZT3Z@142182|Gemmatimonadetes 142182|Gemmatimonadetes V MatE - - - - - - - - - - - - MatE DYD1_k127_322298_2 1492922.GY26_05485 3.378e-13 79.0 COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,1S8DE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein possibly involved in utilization of glycolate and propanediol - - - ko:K11477 - - - - ko00000 - - - Haem_degrading DYD1_k127_322298_0 1340493.JNIF01000003_gene4452 2.962e-119 392.0 COG2382@1|root,COG2382@2|Bacteria 2|Bacteria P enterobactin catabolic process - - 3.6.3.38 ko:K07214,ko:K09689 ko02010,map02010 M00249 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.101 - - Esterase DYD1_k127_322659_0 666509.RCA23_c08390 5.47e-251 780.0 COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the GcvT family - - 2.1.1.341 ko:K15066 ko00627,ko01120,map00627,map01120 - R09271,R10136 RC00113,RC00392 ko00000,ko00001,ko01000 - - - GCV_T,GCV_T_C DYD1_k127_3235694_0 469383.Cwoe_3870 3.606e-142 464.0 COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CS94@84995|Rubrobacteria 201174|Actinobacteria C xanthine dehydrogenase, a b hammerhead - - 1.2.5.3,1.5.99.4 ko:K03520,ko:K19820 ko00760,ko01120,map00760,map01120 M00810 R02860,R07946,R11168 RC00589,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_3236675_7 1182590.BN5_00585 5.767e-08 57.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1YFFD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Trypsin degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 DYD1_k127_3236675_0 498211.CJA_2162 3.734e-135 437.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1FGIT@10|Cellvibrio 1236|Gammaproteobacteria S MCM2/3/5 family moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD1_k127_3236675_2 1121918.ARWE01000001_gene2229 9.367e-69 244.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42US5@68525|delta/epsilon subdivisions,2X5M9@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 DYD1_k127_3236675_5 1485545.JQLW01000009_gene178 7.573e-39 149.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria 1224|Proteobacteria S von Willebrand factor, type A batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA DYD1_k127_3236675_3 395493.BegalDRAFT_0037 1.54e-62 220.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,4604T@72273|Thiotrichales 72273|Thiotrichales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 DYD1_k127_3236675_1 697282.Mettu_1928 3.08e-118 403.0 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1XEC7@135618|Methylococcales 135618|Methylococcales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_2,VWA_2 DYD1_k127_3236675_4 395493.BegalDRAFT_0163 2.073e-62 236.0 COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,460JF@72273|Thiotrichales 72273|Thiotrichales S Oxygen tolerance - - - - - - - - - - - - BatD DYD1_k127_3239377_1 1122176.KB903541_gene286 1.099e-18 94.0 COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes 976|Bacteroidetes P Arylsulfatase - - - - - - - - - - - - Sulfatase DYD1_k127_3239377_0 1242864.D187_003715 2.666e-66 237.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B DYD1_k127_3239377_2 1038869.AXAN01000002_gene336 1.688e-12 75.0 COG2353@1|root,COG2353@2|Bacteria,1RJFZ@1224|Proteobacteria,2VQHC@28216|Betaproteobacteria,1K44N@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the UPF0312 family - - - - - - - - - - - - YceI DYD1_k127_3255084_6 1033802.SSPSH_003117 5.027e-27 114.0 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE DYD1_k127_3255084_1 105559.Nwat_2170 2.408e-88 293.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1WWG3@135613|Chromatiales 135613|Chromatiales K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG DYD1_k127_3255084_2 1158150.KB906251_gene4 6.422e-72 244.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1WXZD@135613|Chromatiales 135613|Chromatiales J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK - - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N DYD1_k127_3255084_0 519989.ECTPHS_13238 1.078e-98 334.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,1WW17@135613|Chromatiales 135613|Chromatiales J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA - - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 DYD1_k127_3255084_3 930169.B5T_03804 1.769e-52 190.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1XJFF@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 DYD1_k127_3255084_5 105559.Nwat_2166 4.276e-43 160.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1WYGN@135613|Chromatiales 135613|Chromatiales J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N DYD1_k127_3255084_4 443152.MDG893_13859 1.165e-49 178.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,464QF@72275|Alteromonadaceae 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 DYD1_k127_3262351_0 1033802.SSPSH_000812 1.153e-106 357.0 COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria 1236|Gammaproteobacteria I synthase - - 2.3.3.10 ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000,ko01008 - - - HMG_CoA_synt_C,HMG_CoA_synt_N DYD1_k127_3262351_2 261292.Nit79A3_0518 4.032e-24 111.0 COG2854@1|root,COG2854@2|Bacteria,1N275@1224|Proteobacteria,2WBHZ@28216|Betaproteobacteria,3735V@32003|Nitrosomonadales 28216|Betaproteobacteria Q MlaC protein - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD1_k127_3262351_1 1500890.JQNL01000001_gene3591 1.331e-33 139.0 COG4969@1|root,COG4969@2|Bacteria,1PD0T@1224|Proteobacteria,1SY74@1236|Gammaproteobacteria,1X7AI@135614|Xanthomonadales 135614|Xanthomonadales NU Tfp pilus assembly protein, major pilin PilA - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - DUF4339,Pilin DYD1_k127_3263929_2 1121440.AUMA01000015_gene1865 6.133e-68 241.0 COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,42QVG@68525|delta/epsilon subdivisions,2WNKA@28221|Deltaproteobacteria,2M9AG@213115|Desulfovibrionales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_3263929_0 1123278.KB893470_gene2819 1.044e-79 278.0 COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,47KEY@768503|Cytophagia 976|Bacteroidetes S Amidinotransferase - - - - - - - - - - - - Amidinotransf DYD1_k127_3263929_1 555793.WSK_2986 1.016e-75 269.0 COG0457@1|root,COG0457@2|Bacteria,1RBEJ@1224|Proteobacteria,2U6X2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - DYD1_k127_3263929_3 402626.Rpic_0855 2.328e-56 210.0 COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2VN9Y@28216|Betaproteobacteria,1K6AS@119060|Burkholderiaceae 28216|Betaproteobacteria S Beta-lactamase superfamily domain - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 DYD1_k127_3263929_4 391600.ABRU01000042_gene2372 8.824e-18 90.0 COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,2UDT4@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_3273267_1 314271.RB2654_06729 1.584e-42 158.0 COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TR6X@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Cytochrome P450 - - - - - - - - - - - - p450 DYD1_k127_3273267_0 314271.RB2654_06739 7.945e-160 514.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM DYD1_k127_3273267_2 1123501.KB902276_gene1359 2.665e-36 145.0 COG3090@1|root,COG3090@2|Bacteria,1RD4B@1224|Proteobacteria,2U8B7@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD1_k127_3273267_3 1123501.KB902276_gene1360 3.463e-07 54.0 COG1638@1|root,COG1638@2|Bacteria,1R4EX@1224|Proteobacteria,2TU3C@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP DYD1_k127_3298503_0 342113.DM82_1103 4.636e-48 179.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2VJP8@28216|Betaproteobacteria,1K05N@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM Gp37Gp68 family protein - - - - - - - - - - - - DUF5131 DYD1_k127_3298799_0 582402.Hbal_0640 5.964e-173 554.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,43WII@69657|Hyphomonadaceae 28211|Alphaproteobacteria S PFAM peptidase M16 domain protein - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_3298799_1 1123261.AXDW01000002_gene1598 1.827e-26 116.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1X4NS@135614|Xanthomonadales 135614|Xanthomonadales M Lytic murein transglycosylase slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L DYD1_k127_3299706_3 1122604.JONR01000005_gene980 8.523e-36 140.0 COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X6CG@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional regulator - - - - - - - - - - - - Rrf2 DYD1_k127_3299706_0 472759.Nhal_0688 3.929e-269 833.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1WWT1@135613|Chromatiales 135613|Chromatiales O TIGRFAM FeS assembly protein SufB - - - ko:K09014 - - - - ko00000 - - - UPF0051 DYD1_k127_3299706_1 1286106.MPL1_10227 2.111e-111 364.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,45ZRE@72273|Thiotrichales 72273|Thiotrichales O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran DYD1_k127_3299706_2 1286106.MPL1_05012 4.952e-56 210.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,460HX@72273|Thiotrichales 72273|Thiotrichales O FeS assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 DYD1_k127_3302072_1 876044.IMCC3088_1539 8.608e-107 351.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1J4R8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 DYD1_k127_3302072_2 519989.ECTPHS_04044 3.771e-38 143.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1WYVD@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 DYD1_k127_3302072_3 754477.Q7C_2169 3.711e-37 143.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,460ZR@72273|Thiotrichales 72273|Thiotrichales J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p DYD1_k127_3302072_0 1236541.BALL01000078_gene4972 6.447e-115 385.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,2Q9PR@267890|Shewanellaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - iYL1228.KPN_03597,ic_1306.c3945 polyprenyl_synt DYD1_k127_3306874_0 1038869.AXAN01000004_gene1203 6.705e-91 316.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K2HZ@119060|Burkholderiaceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_4 DYD1_k127_3306874_1 566466.NOR53_1363 5.328e-33 129.0 COG0624@1|root,COG0624@2|Bacteria,1NYRF@1224|Proteobacteria,1SKIQ@1236|Gammaproteobacteria,1J9JI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD1_k127_3315651_1 414684.RC1_0494 7.753e-35 138.0 COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2U9Z9@28211|Alphaproteobacteria,2JT9W@204441|Rhodospirillales 204441|Rhodospirillales K Transcriptional regulator - - - - - - - - - - - - Rrf2 DYD1_k127_3315651_0 1282876.BAOK01000001_gene2312 1.68e-151 482.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,4BPG7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O FeS assembly protein SufB sufB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - ko:K09014 - - - - ko00000 - - - UPF0051 DYD1_k127_3335081_2 1265505.ATUG01000001_gene3992 3.242e-48 182.0 COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,42TDF@68525|delta/epsilon subdivisions,2WQVE@28221|Deltaproteobacteria,2MNWV@213118|Desulfobacterales 28221|Deltaproteobacteria S Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - ko:K03796 - - - - ko00000 - GH73 - Glucosaminidase DYD1_k127_3335081_1 1122194.AUHU01000014_gene1151 2.819e-84 292.0 COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RP7J@1236|Gammaproteobacteria,466G6@72275|Alteromonadaceae 1236|Gammaproteobacteria G xylanase chitin deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD1_k127_3335081_0 1161401.ASJA01000005_gene2400 9.641e-125 406.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria,440A5@69657|Hyphomonadaceae 28211|Alphaproteobacteria S beta-keto acid cleavage enzyme - - - - - - - - - - - - BKACE DYD1_k127_3335081_3 314275.MADE_1003875 1.289e-42 163.0 COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,464Q4@72275|Alteromonadaceae 1236|Gammaproteobacteria D Protein of unknown function (DUF3450) - - - - - - - - - - - - DUF3450 DYD1_k127_3364338_2 1192868.CAIU01000035_gene4307 1.087e-32 130.0 COG1695@1|root,COG1695@2|Bacteria,1PMEP@1224|Proteobacteria,2V018@28211|Alphaproteobacteria,43QT4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR DYD1_k127_3364338_1 1123229.AUBC01000008_gene379 1.3e-33 140.0 COG0730@1|root,COG0730@2|Bacteria,1MWAN@1224|Proteobacteria,2TS4X@28211|Alphaproteobacteria,3JS3F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S membrane transporter protein MA20_06400 - - ko:K07090 - - - - ko00000 - - - TauE DYD1_k127_3364338_0 1288494.EBAPG3_12540 2.132e-71 255.0 COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2WC7C@28216|Betaproteobacteria,374E4@32003|Nitrosomonadales 28216|Betaproteobacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - DYD1_k127_3373885_2 627192.SLG_31400 2.217e-29 121.0 COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_3373885_1 886293.Sinac_1155 9.866e-59 224.0 COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes 203682|Planctomycetes S Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_4 DYD1_k127_3373885_3 497964.CfE428DRAFT_1650 3.279e-08 66.0 2DSFU@1|root,33FZH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3373885_0 97096.XP_007790920.1 1.048e-77 279.0 COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes 4751|Fungi S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD1_k127_3393628_4 1218074.BAXZ01000026_gene4634 2.008e-68 236.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2VJ1C@28216|Betaproteobacteria,1K27J@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM Alcohol dehydrogenase zinc-binding domain protein - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_3393628_2 767434.Fraau_2835 2.341e-85 290.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1X34D@135614|Xanthomonadales 135614|Xanthomonadales C electron transfer flavoprotein beta subunit etfB - - ko:K03521 - - - - ko00000 - - - ETF DYD1_k127_3393628_1 1123377.AUIV01000011_gene2073 4.364e-110 368.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,1X4RW@135614|Xanthomonadales 135614|Xanthomonadales C Electron transfer flavoprotein etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha DYD1_k127_3393628_5 1247963.JPHU01000008_gene2895 6.955e-54 196.0 COG0406@1|root,COG0406@2|Bacteria,1N83T@1224|Proteobacteria,2UFAK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 DYD1_k127_3393628_3 1232410.KI421413_gene633 9.209e-79 265.0 2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,42QWQ@68525|delta/epsilon subdivisions,2WMRI@28221|Deltaproteobacteria,43T93@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3393628_0 523791.Kkor_1351 3.724e-164 525.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XI9V@135619|Oceanospirillales 135619|Oceanospirillales P Sodium proton antiporter - - - - - - - - - - - - CitMHS DYD1_k127_3404080_1 1232453.BAIF02000008_gene2985 9.479e-60 215.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia 186801|Clostridia S Dihydroxyacetone kinase, L subunit - - 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 DYD1_k127_3404080_0 1232453.BAIF02000008_gene2986 2.254e-149 479.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia 186801|Clostridia G Dihydroxyacetone kinase dhaK - 2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01059 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Dak1,Dak2 DYD1_k127_3404080_2 1122139.KB907874_gene2630 4.298e-18 87.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1XJNK@135619|Oceanospirillales 135619|Oceanospirillales G Phosphoglycolate phosphatase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 DYD1_k127_3408109_1 626418.bglu_1g19880 2.145e-12 79.0 COG2831@1|root,COG2831@2|Bacteria,1R43A@1224|Proteobacteria,2VN1X@28216|Betaproteobacteria,1K1EM@119060|Burkholderiaceae 28216|Betaproteobacteria U PFAM Polypeptide-transport-associated domain protein ShlB-type - - - - - - - - - - - - POTRA_2,ShlB DYD1_k127_3408109_0 1245469.S58_20770 1.022e-13 83.0 COG4254@1|root,COG4254@2|Bacteria,1MV4V@1224|Proteobacteria,2TV9X@28211|Alphaproteobacteria,3JVW5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S FecR protein - - - - - - - - - - - - FecR DYD1_k127_3436847_0 344747.PM8797T_14147 6.505e-60 210.0 COG0436@1|root,COG0436@2|Bacteria,2IXM3@203682|Planctomycetes 203682|Planctomycetes E Aminotransferase class I and II - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_3436847_2 1123267.JONN01000001_gene1975 1.301e-27 121.0 COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,2KDKH@204457|Sphingomonadales 204457|Sphingomonadales S Methyltransferase - - - - - - - - - - - - Methyltransf_25,PCMT DYD1_k127_3436847_1 330214.NIDE0547 2.657e-51 205.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD1_k127_3436847_3 1137799.GZ78_18150 8.951e-25 117.0 COG0457@1|root,COG3710@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1XMP3@135619|Oceanospirillales 135619|Oceanospirillales K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - TPR_16,Trans_reg_C DYD1_k127_3439246_3 644966.Tmar_2279 9.354e-09 59.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3WCK3@538999|Clostridiales incertae sedis 186801|Clostridia J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p DYD1_k127_3439246_0 1267535.KB906767_gene3728 3.089e-56 214.0 COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia 204432|Acidobacteriia M Belongs to the ompA family - - - - - - - - - - - - OmpA DYD1_k127_3439246_1 1117647.M5M_15820 1.914e-44 168.0 COG2930@1|root,COG2930@2|Bacteria,1RCYH@1224|Proteobacteria,1S41U@1236|Gammaproteobacteria,1J6CJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S s cog2930 CT2216 - - - - - - - - - - - Ysc84 DYD1_k127_3439246_2 1123393.KB891333_gene2534 2.301e-13 72.0 2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,2VYEK@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3450316_0 1038860.AXAP01000018_gene3108 1.235e-83 293.0 COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,1PIDE@1224|Proteobacteria,2TTS3@28211|Alphaproteobacteria,3JVPI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C PQQ-like domain - - 1.1.2.6 ko:K05889 - - R03136 - ko00000,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3 DYD1_k127_3450316_1 1168289.AJKI01000001_gene3593 1.969e-66 244.0 COG0841@1|root,COG1131@1|root,COG0841@2|Bacteria,COG1131@2|Bacteria,4NDZG@976|Bacteroidetes,2FM3B@200643|Bacteroidia,3XJRA@558415|Marinilabiliaceae 976|Bacteroidetes V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran DYD1_k127_3456485_0 187272.Mlg_1175 2.149e-251 789.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1WW62@135613|Chromatiales 135613|Chromatiales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon DYD1_k127_3464292_1 1211115.ALIQ01000198_gene440 2.587e-112 369.0 COG0559@1|root,COG0559@2|Bacteria,1N90R@1224|Proteobacteria,2TS95@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component MA20_14115 - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_3464292_0 1211115.ALIQ01000198_gene441 6.206e-118 385.0 COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the binding-protein-dependent transport system permease family MA20_14120 - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 DYD1_k127_3465596_0 498211.CJA_0589 2.295e-113 382.0 COG2982@1|root,COG2982@2|Bacteria,1QVU8@1224|Proteobacteria,1T2J0@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - He_PIG,OMP_b-brl DYD1_k127_3465596_1 1142394.PSMK_28130 4.582e-35 150.0 2DRTQ@1|root,32URN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3465596_2 1122164.JHWF01000022_gene1733 4.037e-06 52.0 2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - DYD1_k127_3469937_3 765913.ThidrDRAFT_3271 1.029e-09 70.0 COG1716@1|root,COG3267@1|root,COG1716@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Type II secretory pathway component ExeA gspA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1,T2SSB DYD1_k127_3469937_1 519989.ECTPHS_03662 4.7e-56 197.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1WYCP@135613|Chromatiales 135613|Chromatiales K PFAM regulatory protein, MerR - - - - - - - - - - - - MerR_1 DYD1_k127_3469937_2 318161.Sden_1604 1.785e-43 160.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,2QC5B@267890|Shewanellaceae 1236|Gammaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD1_k127_3469937_0 349124.Hhal_0432 1.39e-134 445.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1WW51@135613|Chromatiales 135613|Chromatiales J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind DYD1_k127_3471280_0 1185876.BN8_02405 1.324e-47 184.0 COG2706@1|root,COG2706@2|Bacteria,4PPTA@976|Bacteroidetes 976|Bacteroidetes G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS DYD1_k127_3471280_3 1121022.ABENE_22105 2.926e-29 121.0 COG1426@1|root,COG1426@2|Bacteria,1QW1U@1224|Proteobacteria,2UGR0@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,HTH_31 DYD1_k127_3471280_2 1280941.HY2_01850 8.686e-37 141.0 COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2TUX1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein related to capsule biosynthesis enzymes - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C DYD1_k127_3471280_1 1280953.HOC_13244 6.802e-39 147.0 COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,2TUX1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein related to capsule biosynthesis enzymes - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C DYD1_k127_3507009_2 1286106.MPL1_06089 1.111e-113 384.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,45ZN8@72273|Thiotrichales 72273|Thiotrichales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG DYD1_k127_3507009_5 1121013.P873_11735 4.743e-31 126.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1X7J1@135614|Xanthomonadales 135614|Xanthomonadales U Preprotein translocase subunit YajC yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC DYD1_k127_3507009_0 713586.KB900536_gene425 4.087e-171 544.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1WWQ8@135613|Chromatiales 135613|Chromatiales J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT DYD1_k127_3507009_1 519989.ECTPHS_05526 7.507e-124 406.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales 135613|Chromatiales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth DYD1_k127_3507009_3 1268237.G114_10900 2.08e-97 323.0 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,1Y52X@135624|Aeromonadales 135624|Aeromonadales P membrane protein, TerC - - - - - - - - - - - - TerC DYD1_k127_3507009_4 1384054.N790_07565 5.83e-57 206.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1X3T4@135614|Xanthomonadales 135614|Xanthomonadales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 DYD1_k127_3507009_6 228410.NE1458 2.655e-24 102.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,371QG@32003|Nitrosomonadales 28216|Betaproteobacteria D Tyrosine recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_3513754_0 396588.Tgr7_2948 7.794e-82 296.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1WXRZ@135613|Chromatiales 135613|Chromatiales M PFAM AsmA family protein - - - ko:K07289 - - - - ko00000 - - - AsmA DYD1_k127_3515052_3 395493.BegalDRAFT_0163 3.242e-05 49.0 COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,460JF@72273|Thiotrichales 72273|Thiotrichales S Oxygen tolerance - - - - - - - - - - - - BatD DYD1_k127_3515052_1 1226994.AMZB01000137_gene5385 6.309e-56 211.0 COG2199@1|root,COG3706@2|Bacteria,1RDWG@1224|Proteobacteria,1S7W2@1236|Gammaproteobacteria,1YEDJ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF DYD1_k127_3515052_0 1333998.M2A_0574 1.687e-71 243.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,4BS74@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gloA GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD1_k127_3515052_2 580332.Slit_2150 3.449e-47 180.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - DYD1_k127_3519336_2 582402.Hbal_1149 6.748e-15 76.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,43WGJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N DYD1_k127_3519336_1 313628.LNTAR_09736 9.93e-34 142.0 COG4099@1|root,COG4099@2|Bacteria 2|Bacteria F phospholipase Carboxylesterase - - - - - - - - - - - - Abhydrolase_2,Abhydrolase_8,DLH,Esterase,Peptidase_S9 DYD1_k127_3519336_0 316057.RPD_1884 2.122e-142 462.0 COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2TRB8@28211|Alphaproteobacteria,3JSNQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH FAD binding domain pobA GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016709,GO:0018659,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.14.13.2 ko:K00481 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R01298 RC00046 ko00000,ko00001,ko01000 - - - FAD_binding_3 DYD1_k127_3523278_0 768671.ThimaDRAFT_1160 0.0 1320.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales 135613|Chromatiales EF Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS DYD1_k127_3530921_1 765910.MARPU_15660 4.068e-115 381.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales 135613|Chromatiales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP DYD1_k127_3530921_0 675812.VHA_003213 2.351e-207 653.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1XV77@135623|Vibrionales 135623|Vibrionales J COG0008 Glutamyl- and glutaminyl-tRNA synthetases glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C DYD1_k127_3530921_4 344747.PM8797T_03995 3.87e-29 119.0 COG0008@1|root,COG0008@2|Bacteria,2IYSE@203682|Planctomycetes 203682|Planctomycetes J tRNA synthetases class I (E and Q), anti-codon binding domain glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C DYD1_k127_3530921_2 471852.Tcur_1573 1.692e-83 293.0 COG0277@1|root,COG0277@2|Bacteria,2GKQR@201174|Actinobacteria,4EFTT@85012|Streptosporangiales 201174|Actinobacteria C FAD binding domain - - - - - - - - - - - - FAD_binding_4 DYD1_k127_3530921_3 713586.KB900536_gene2819 4.951e-49 177.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales 135613|Chromatiales M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS DYD1_k127_3533209_3 435908.IDSA_06445 8.915e-22 94.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,2QF2Z@267893|Idiomarinaceae 1236|Gammaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - iJN746.PP_4169,iSFV_1184.SFV_3923 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N DYD1_k127_3533209_4 1121874.KB892377_gene1348 3.988e-10 61.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,3VP9S@526524|Erysipelotrichia 526524|Erysipelotrichia I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N DYD1_k127_3533209_2 1114970.PSF113_0358 1.123e-60 213.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1YPWF@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD1_k127_3533209_0 1049564.TevJSym_at00180 7.927e-142 460.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1J5J9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the dihydroorotate dehydrogenase family pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh,NAD_binding_1 DYD1_k127_3533209_1 1469245.JFBG01000080_gene290 8.427e-94 316.0 COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria 1224|Proteobacteria S TGS domain - - - ko:K06944 - - - - ko00000 - - - MMR_HSR1,TGS DYD1_k127_3537391_0 1121013.P873_07250 2.448e-101 347.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1X4J8@135614|Xanthomonadales 135614|Xanthomonadales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF DYD1_k127_354173_0 768671.ThimaDRAFT_3347 6.283e-109 363.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales 135613|Chromatiales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 DYD1_k127_354173_1 377629.TERTU_3705 4.524e-59 209.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,2PNBD@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria K ATP cone domain nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone DYD1_k127_354173_2 395493.BegalDRAFT_0286 7.842e-13 69.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,45ZMT@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT DYD1_k127_3545556_0 1265503.KB905166_gene923 5.065e-180 574.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Gamma-glutamyltransferase ggt_1 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD1_k127_3545556_3 1121013.P873_10205 2.19e-21 98.0 2E6T1@1|root,315CH@2|Bacteria,1P8MQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_3545556_2 261292.Nit79A3_2588 6.445e-24 104.0 COG2119@1|root,COG2119@2|Bacteria 2|Bacteria O membrane - - - - - - - - - - - - UPF0016 DYD1_k127_3545556_4 1112212.JH584235_gene1042 7.544e-16 85.0 2ANK7@1|root,31DJB@2|Bacteria,1R2CN@1224|Proteobacteria,2TZHE@28211|Alphaproteobacteria,2KETJ@204457|Sphingomonadales 204457|Sphingomonadales S Cytochrome P460 - - - - - - - - - - - - Cytochrome_P460 DYD1_k127_3545556_1 1040989.AWZU01000023_gene4896 7.991e-29 118.0 28JPA@1|root,2Z9FC@2|Bacteria,1PN1F@1224|Proteobacteria,2TSKX@28211|Alphaproteobacteria,3JT6R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3549026_3 6211.A0A068Y9K1 2.02e-11 75.0 COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria 33208|Metazoa M ankyrin 3, node of Ranvier (ankyrin G) ANK2 GO:0000226,GO:0000278,GO:0000281,GO:0000323,GO:0000902,GO:0000904,GO:0000910,GO:0001508,GO:0002027,GO:0002028,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003205,GO:0003230,GO:0003254,GO:0003279,GO:0003283,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005783,GO:0005794,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0005911,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006888,GO:0006892,GO:0006893,GO:0006928,GO:0006935,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0006996,GO:0007009,GO:0007010,GO:0007016,GO:0007017,GO:0007049,GO:0007154,GO:0007165,GO:0007267,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007507,GO:0007528,GO:0007600,GO:0007605,GO:0007610,GO:0007611,GO:0007613,GO:0007614,GO:0008015,GO:0008016,GO:0008092,GO:0008104,GO:0008150,GO:0008582,GO:0009605,GO:0009653,GO:0009893,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010171,GO:0010256,GO:0010468,GO:0010522,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010648,GO:0010649,GO:0010650,GO:0010765,GO:0010880,GO:0010881,GO:0010882,GO:0010959,GO:0010960,GO:0012505,GO:0014069,GO:0014704,GO:0014731,GO:0015031,GO:0015459,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016049,GO:0016192,GO:0016247,GO:0016323,GO:0016328,GO:0016528,GO:0016529,GO:0019222,GO:0019226,GO:0019228,GO:0019722,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0022008,GO:0022402,GO:0022407,GO:0022409,GO:0022607,GO:0022898,GO:0023051,GO:0023052,GO:0023057,GO:0030001,GO:0030003,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030048,GO:0030054,GO:0030154,GO:0030155,GO:0030182,GO:0030315,GO:0030424,GO:0030425,GO:0030507,GO:0030674,GO:0031175,GO:0031224,GO:0031226,GO:0031430,GO:0031594,GO:0031647,GO:0031672,GO:0031674,GO:0032026,GO:0032279,GO:0032386,GO:0032388,GO:0032409,GO:0032410,GO:0032411,GO:0032412,GO:0032413,GO:0032414,GO:0032501,GO:0032502,GO:0032507,GO:0032879,GO:0032880,GO:0032970,GO:0032989,GO:0032990,GO:0033036,GO:0033157,GO:0033267,GO:0033268,GO:0033270,GO:0033292,GO:0033365,GO:0033563,GO:0034110,GO:0034112,GO:0034394,GO:0034613,GO:0034762,GO:0034763,GO:0034764,GO:0034765,GO:0034766,GO:0034767,GO:0035556,GO:0035637,GO:0036062,GO:0036309,GO:0036371,GO:0036477,GO:0040007,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042592,GO:0042692,GO:0042734,GO:0042886,GO:0042995,GO:0043001,GO:0043005,GO:0043034,GO:0043194,GO:0043195,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043266,GO:0043267,GO:0043268,GO:0043269,GO:0043270,GO:0043271,GO:0043292,GO:0043679,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044091,GO:0044092,GO:0044093,GO:0044291,GO:0044304,GO:0044306,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045170,GO:0045184,GO:0045185,GO:0045202,GO:0045211,GO:0045296,GO:0045760,GO:0045785,GO:0045838,GO:0045887,GO:0045927,GO:0046907,GO:0048193,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048588,GO:0048589,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048675,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050803,GO:0050804,GO:0050805,GO:0050807,GO:0050808,GO:0050821,GO:0050839,GO:0050877,GO:0050890,GO:0050896,GO:0050954,GO:0051049,GO:0051050,GO:0051051,GO:0051094,GO:0051117,GO:0051128,GO:0051130,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051270,GO:0051279,GO:0051282,GO:0051301,GO:0051641,GO:0051649,GO:0051651,GO:0051716,GO:0051899,GO:0051924,GO:0051928,GO:0051960,GO:0051962,GO:0051963,GO:0051965,GO:0055001,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055117,GO:0060047,GO:0060048,GO:0060090,GO:0060249,GO:0060255,GO:0060306,GO:0060307,GO:0060341,GO:0060560,GO:0061024,GO:0061061,GO:0061337,GO:0061564,GO:0061640,GO:0061951,GO:0065007,GO:0065008,GO:0065009,GO:0070050,GO:0070201,GO:0070252,GO:0070296,GO:0070727,GO:0070838,GO:0070887,GO:0070972,GO:0071241,GO:0071248,GO:0071286,GO:0071702,GO:0071705,GO:0071709,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0072657,GO:0072658,GO:0072659,GO:0072660,GO:0086001,GO:0086002,GO:0086003,GO:0086004,GO:0086005,GO:0086010,GO:0086012,GO:0086014,GO:0086015,GO:0086018,GO:0086019,GO:0086026,GO:0086036,GO:0086046,GO:0086065,GO:0086066,GO:0086070,GO:0086091,GO:0090087,GO:0090150,GO:0090257,GO:0090313,GO:0090314,GO:0090316,GO:0097060,GO:0097447,GO:0097458,GO:0097485,GO:0098590,GO:0098771,GO:0098772,GO:0098793,GO:0098794,GO:0098876,GO:0098900,GO:0098901,GO:0098902,GO:0098904,GO:0098907,GO:0098910,GO:0098984,GO:0099080,GO:0099081,GO:0099106,GO:0099177,GO:0099512,GO:0099572,GO:0099612,GO:0099623,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1900073,GO:1900074,GO:1900825,GO:1900827,GO:1901016,GO:1901017,GO:1901018,GO:1901019,GO:1901021,GO:1901379,GO:1901380,GO:1901381,GO:1902259,GO:1902260,GO:1902305,GO:1902307,GO:1903047,GO:1903115,GO:1903169,GO:1903522,GO:1903533,GO:1903779,GO:1903817,GO:1903827,GO:1903829,GO:1904062,GO:1904063,GO:1904064,GO:1904181,GO:1904396,GO:1904398,GO:1904427,GO:1904951,GO:1905475,GO:1905477,GO:1990138,GO:1990778,GO:2000026,GO:2000649,GO:2000651,GO:2001257,GO:2001258,GO:2001259 1.14.11.27 ko:K10277,ko:K10380 ko04624,ko05205,map04624,map05205 - - - ko00000,ko00001,ko01000,ko03036,ko04812 - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5,Death,ZU5 DYD1_k127_3549026_2 319236.JCM19294_967 2.639e-33 133.0 COG3422@1|root,COG3422@2|Bacteria,4NS9J@976|Bacteroidetes,1I40P@117743|Flavobacteriia,3HKID@363408|Nonlabens 976|Bacteroidetes S Domain of unknown function (DUF1508) - - - ko:K09946 - - - - ko00000 - - - DUF1508 DYD1_k127_3549026_5 1297742.A176_03314 0.0001795 53.0 2ARRP@1|root,31H2U@2|Bacteria,1QAH8@1224|Proteobacteria,43534@68525|delta/epsilon subdivisions,2WZE7@28221|Deltaproteobacteria,2Z1XY@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3549026_0 1121949.AQXT01000002_gene1757 1.916e-205 656.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,43WBM@69657|Hyphomonadaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 DYD1_k127_3549026_1 399795.CtesDRAFT_PD1614 5.839e-166 535.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VI4U@28216|Betaproteobacteria,4ABS2@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B ligB - 1.13.11.57 ko:K04099 ko00627,ko01120,map00627,map01120 - R03550,R04280,R09565 RC00233,RC00535,RC02567,RC02694 ko00000,ko00001,ko01000 - - - LigA,LigB DYD1_k127_3549026_4 1028801.RG1141_PA07520 2.297e-10 66.0 COG1028@1|root,COG1028@2|Bacteria,1PH59@1224|Proteobacteria,2URAK@28211|Alphaproteobacteria,4BIRM@82115|Rhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 DYD1_k127_3552217_5 1280947.HY30_11645 0.0002281 47.0 COG3909@1|root,COG3909@2|Bacteria,1Q594@1224|Proteobacteria,2UG98@28211|Alphaproteobacteria,43YF3@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Cytochrome C' - - - - - - - - - - - - Cytochrom_C_2 DYD1_k127_3552217_1 420324.KI912045_gene4419 4.246e-84 295.0 COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,1JTF7@119045|Methylobacteriaceae 28211|Alphaproteobacteria O Trypsin-like peptidase domain MA20_20705 - - - - - - - - - - - PDZ_2,Trypsin_2 DYD1_k127_3552217_2 1131553.JIBI01000005_gene2164 5.419e-75 265.0 COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,2W832@28216|Betaproteobacteria,372AS@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 DYD1_k127_3552217_4 1218084.BBJK01000002_gene230 2.12e-26 113.0 COG1846@1|root,COG1846@2|Bacteria,1RCY7@1224|Proteobacteria,2VSV9@28216|Betaproteobacteria,1K7ZT@119060|Burkholderiaceae 28216|Betaproteobacteria K homoprotocatechuate degradation operon regulator, HpaR hpaR - - - - - - - - - - - MarR,MarR_2 DYD1_k127_3552217_0 1037409.BJ6T_67990 5.441e-106 351.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria,3JSMG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family MA20_16265 - - - - - - - - - - - FAA_hydrolase DYD1_k127_3552217_3 1218084.BBJK01000086_gene5801 1.162e-60 212.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,1KC0C@119060|Burkholderiaceae 28216|Betaproteobacteria E Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD1_k127_3565691_1 706587.Desti_3962 0.0001181 52.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus - - - ko:K21440 - - - - ko00000,ko04131 - - - Ank_2,Ank_3,Ank_4,Ank_5 DYD1_k127_3565691_0 1183438.GKIL_2151 2.611e-135 450.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1,Amidohydro_3 DYD1_k127_3580841_0 420662.Mpe_A1225 5.236e-157 516.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,2VZ4H@28216|Betaproteobacteria,1KN47@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 DYD1_k127_3597398_0 946362.XP_004997433.1 2.706e-69 246.0 KOG1406@1|root,KOG1406@2759|Eukaryota,38CKQ@33154|Opisthokonta 33154|Opisthokonta I propanoyl-CoA C-acyltransferase activity - - - - - - - - - - - - Thiolase_C,Thiolase_N DYD1_k127_3597398_1 876269.ARWA01000001_gene848 3.501e-57 209.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria,3NAN7@45404|Beijerinckiaceae 28211|Alphaproteobacteria E Pyrroline-5-carboxylate reductase dimerisation proC GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer DYD1_k127_3602551_1 1122134.KB893650_gene34 2.117e-58 210.0 COG0654@1|root,COG0654@2|Bacteria,1R7UC@1224|Proteobacteria,1S1B9@1236|Gammaproteobacteria,1XQV5@135619|Oceanospirillales 135619|Oceanospirillales CH FAD binding domain - - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD1_k127_3602551_0 598467.BrE312_3533 1.649e-132 432.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422 Thymidylat_synt DYD1_k127_3602551_2 270374.MELB17_19199 3.117e-56 199.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,4655B@72275|Alteromonadaceae 1236|Gammaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD1_k127_3606796_1 1123279.ATUS01000002_gene174 1.507e-90 303.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1J5BU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin DYD1_k127_3606796_0 1122212.AULO01000007_gene2301 9.457e-132 426.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1XIMD@135619|Oceanospirillales 135619|Oceanospirillales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC DYD1_k127_3606796_2 391615.ABSJ01000032_gene731 6.807e-30 126.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1JAGN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD1_k127_3621671_3 314285.KT71_17331 1.269e-57 203.0 COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,1S5XU@1236|Gammaproteobacteria,1J8IK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Putative zinc- or iron-chelating domain ycgN - - ko:K09160 - - - - ko00000 - - - CxxCxxCC DYD1_k127_3621671_0 765913.ThidrDRAFT_3979 1.593e-99 334.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1WW4Q@135613|Chromatiales 135613|Chromatiales CH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_3621671_1 1121015.N789_12150 2.476e-80 275.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1X623@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_3621671_2 1122139.KB907869_gene936 3.573e-58 214.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1XJIV@135619|Oceanospirillales 135619|Oceanospirillales E COG2755 Lysophospholipase L1 and related esterases tesA - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 DYD1_k127_3621671_4 521719.ATXQ01000001_gene340 0.0006373 44.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1YE99@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain fadD1 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD1_k127_3637851_1 1122214.AQWH01000011_gene2170 3.899e-08 57.0 COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TSWP@28211|Alphaproteobacteria 28211|Alphaproteobacteria E lysine exporter protein (LysE YggA) - - - - - - - - - - - - LysE DYD1_k127_3637851_0 153948.NAL212_0916 3.278e-119 395.0 COG0628@1|root,COG0628@2|Bacteria,1PTH3@1224|Proteobacteria 1224|Proteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD1_k127_3644734_0 519989.ECTPHS_02531 6.373e-138 464.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales 135613|Chromatiales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C DYD1_k127_3644734_1 1123368.AUIS01000005_gene328 5.215e-64 226.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,2NC6M@225057|Acidithiobacillales 225057|Acidithiobacillales JM Nucleotidyl transferase - - 2.7.7.99 ko:K00992 ko00520,ko01100,map00520,map01100 - R11025 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase DYD1_k127_3644734_2 1120983.KB894571_gene2129 4.035e-33 132.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,1JPY3@119043|Rhodobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_3660944_0 675806.VII_002378 1.024e-143 463.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1XSW9@135623|Vibrionales 135623|Vibrionales C Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid - - 1.2.1.60 ko:K00151 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04418 RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_3660944_2 675806.VII_002377 1.986e-30 124.0 COG3232@1|root,COG3232@2|Bacteria,1RB8A@1224|Proteobacteria,1S3SG@1236|Gammaproteobacteria,1Y17G@135623|Vibrionales 135623|Vibrionales G 5-carboxymethyl-2-hydroxymuconate isomerase - - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - CHMI DYD1_k127_3660944_1 1003200.AXXA_06238 3.885e-36 140.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,3T1JC@506|Alcaligenaceae 28216|Betaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD1_k127_3665846_0 627192.SLG_06600 1.727e-92 336.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2K3KA@204457|Sphingomonadales 28211|Alphaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_3665846_1 1044.EH31_05300 2.882e-41 168.0 COG1858@1|root,COG1858@2|Bacteria,1QUP2@1224|Proteobacteria,2TW2M@28211|Alphaproteobacteria,2KCYB@204457|Sphingomonadales 204457|Sphingomonadales P ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS DYD1_k127_3669067_0 1267534.KB906756_gene100 2.374e-127 428.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria 2|Bacteria D von Willebrand factor, type A - - - - - - - - - - - - GATase1_like DYD1_k127_3669067_1 926566.Terro_0570 1.71e-46 181.0 COG4249@1|root,COG4249@2|Bacteria,3Y6DQ@57723|Acidobacteria,2JMKY@204432|Acidobacteriia 204432|Acidobacteriia S Peptidase C14 caspase catalytic subunit p20 - - - - - - - - - - - - - DYD1_k127_3669067_2 1267535.KB906767_gene907 4.551e-44 175.0 COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria 2|Bacteria S peptidyl-tyrosine sulfation - - - - - - - - - - - - Peptidase_M1,TPR_16,TPR_19,TPR_8 DYD1_k127_367407_0 1385517.N800_13180 3.52e-280 891.0 COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1QZFW@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - DUF11,SdrD_B DYD1_k127_3687693_1 316273.XCV1085 7.183e-64 237.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1X4BU@135614|Xanthomonadales 135614|Xanthomonadales O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 DYD1_k127_3687693_0 1384056.N787_07910 8.374e-105 346.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1X4CF@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes a key regulatory step in fatty acid biosynthesis - - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_3687693_2 1122212.AULO01000008_gene1319 1.211e-51 188.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XI2V@135619|Oceanospirillales 135619|Oceanospirillales M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD1_k127_3687701_0 1211777.BN77_p10776 2.395e-97 322.0 COG0604@1|root,COG0604@2|Bacteria,1MU4N@1224|Proteobacteria,2TRDI@28211|Alphaproteobacteria,4B71T@82115|Rhizobiaceae 28211|Alphaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 DYD1_k127_3687701_3 159087.Daro_3432 2.315e-58 209.0 2DN41@1|root,32VEA@2|Bacteria,1N23Y@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_3687701_2 1340493.JNIF01000003_gene3859 7.544e-70 248.0 COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria 57723|Acidobacteria S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B DYD1_k127_3687701_4 1122604.JONR01000023_gene4209 4.943e-19 88.0 2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria,1SJFZ@1236|Gammaproteobacteria,1X82Y@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD1_k127_3687701_1 1120956.JHZK01000010_gene2758 8.607e-87 297.0 COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2TZDG@28211|Alphaproteobacteria,1JNHY@119043|Rhodobiaceae 28211|Alphaproteobacteria C Acetyl-CoA hydrolase/transferase C-terminal domain - - - - - - - - - - - - AcetylCoA_hyd_C DYD1_k127_3691154_0 338963.Pcar_0385 5.474e-145 478.0 COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,43BJ2@68525|delta/epsilon subdivisions,2X75C@28221|Deltaproteobacteria,43UGU@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Secretin N-terminal domain - - - ko:K02453,ko:K12282 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N_2 DYD1_k127_3691154_1 1121918.ARWE01000001_gene941 9.457e-27 119.0 COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,430TG@68525|delta/epsilon subdivisions,2WVW5@28221|Deltaproteobacteria,43V8Z@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Type II secretion system (T2SS), protein M - - - ko:K12280 - - - - ko00000,ko02044 - - - T2SSM DYD1_k127_3691154_2 443152.MDG893_13659 2.449e-16 86.0 COG3166@1|root,COG3166@2|Bacteria,1N82E@1224|Proteobacteria,1RTX3@1236|Gammaproteobacteria,4696N@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Fimbrial assembly protein (PilN) - - - ko:K12279 - - - - ko00000,ko02044 - - - PilN DYD1_k127_3695661_1 1122603.ATVI01000005_gene3187 2.866e-53 189.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1X2YM@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N DYD1_k127_3695661_3 1385515.N791_06450 1.293e-13 75.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1X7C1@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC DYD1_k127_3695661_2 1260251.SPISAL_04375 4.943e-33 143.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1X2FV@135613|Chromatiales 135613|Chromatiales S Smr protein - - - - - - - - - - - - Smr DYD1_k127_3695661_0 472759.Nhal_2432 3.467e-98 327.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales 135613|Chromatiales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD1_k127_3704516_0 349521.HCH_00543 2.272e-105 357.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XIUV@135619|Oceanospirillales 135619|Oceanospirillales NT chemotaxis protein - - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ DYD1_k127_3704516_1 1123257.AUFV01000008_gene684 2.559e-35 144.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1X6ZM@135614|Xanthomonadales 135614|Xanthomonadales NT Two component signalling adaptor domain - - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW DYD1_k127_3704516_2 1198452.Jab_2c28680 7.511e-20 89.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,474F2@75682|Oxalobacteraceae 28216|Betaproteobacteria KT cheY-homologous receiver domain pilH - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg DYD1_k127_3708001_0 443152.MDG893_12904 9.936e-124 423.0 COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae 1236|Gammaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,VWA_2 DYD1_k127_3708001_2 395493.BegalDRAFT_3059 8.573e-13 77.0 COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,46154@72273|Thiotrichales 72273|Thiotrichales NU TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl DYD1_k127_3708001_1 566466.NOR53_274 6.036e-33 130.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1J86J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 DYD1_k127_373049_0 861299.J421_0317 1.346e-200 647.0 28JZZ@1|root,2Z9PZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_373049_1 767434.Fraau_0356 1.495e-133 434.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1X3G9@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus DYD1_k127_373049_2 382464.ABSI01000010_gene3557 2.46e-71 254.0 COG4152@1|root,COG4152@2|Bacteria 2|Bacteria S ATPase activity natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 DYD1_k127_373049_3 1047013.AQSP01000052_gene2599 1.187e-34 149.0 COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria 2|Bacteria CP ABC-2 family transporter protein natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD1_k127_3736263_0 573413.Spirs_0874 3.092e-70 257.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - Cu_amine_oxidN1,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2 DYD1_k127_3766208_2 247633.GP2143_08639 6.644e-31 128.0 2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,1S8JT@1236|Gammaproteobacteria,1J70S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2721) - - - - - - - - - - - - DUF2721 DYD1_k127_3766208_1 715451.ambt_12010 3.123e-54 207.0 2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3766208_0 1232410.KI421425_gene1552 0.0 1221.0 COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales 28221|Deltaproteobacteria M OmpA family - - - - - - - - - - - - OmpA DYD1_k127_3767342_4 298653.Franean1_3293 1.733e-41 166.0 28JDP@1|root,32SV2@2|Bacteria,2IPQY@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_3767342_3 536019.Mesop_2057 9.748e-69 239.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2U220@28211|Alphaproteobacteria,43I53@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T response regulator receiver nasT - - ko:K07183 - - - - ko00000,ko02022 - - - ANTAR,Response_reg DYD1_k127_3767342_2 1028801.RG1141_CH33360 9.4e-89 309.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria,4B9Y4@82115|Rhizobiaceae 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components MA20_13115 - - ko:K15576,ko:K22067 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000,ko02022 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 DYD1_k127_3767342_0 1469613.JT55_01525 1.606e-236 739.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components nasF - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 DYD1_k127_3767342_1 1415756.JQMY01000001_gene3628 7.024e-145 466.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2TQT6@28211|Alphaproteobacteria,2PDUT@252301|Oceanicola 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component nasE - - ko:K02050,ko:K15577 ko00910,ko02010,map00910,map02010 M00188,M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17 - - BPD_transp_1 DYD1_k127_3772028_1 1089552.KI911559_gene1088 1.364e-67 231.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2JQ3S@204441|Rhodospirillales 204441|Rhodospirillales S Carbon-nitrogen hydrolase - - 3.5.1.6 ko:K01431 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R00905,R04666,R08228 RC00096 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase DYD1_k127_3772028_0 553385.JEMF01000039_gene2894 1.328e-222 698.0 COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,1RSR2@1236|Gammaproteobacteria,1XIA6@135619|Oceanospirillales 135619|Oceanospirillales FH cytosine purines uracil thiamine allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur DYD1_k127_3772028_2 640511.BC1002_6354 1.311e-17 83.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2VJZV@28216|Betaproteobacteria,1JZP7@119060|Burkholderiaceae 28216|Betaproteobacteria F Catalyzes the hydrolytic cleavage of imides that range from linear to heterocyclic and that include hydantoins, dihydropyrimidines, and phthalimides dht - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 DYD1_k127_3789961_0 1517416.IDAT_04450 1.683e-183 591.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QEXG@267893|Idiomarinaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family acrF - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD1_k127_3789961_1 435908.IDSA_08310 8.01e-17 83.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,2QFFN@267893|Idiomarinaceae 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 DYD1_k127_3807239_1 631362.Thi970DRAFT_00999 9.118e-54 193.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1WY50@135613|Chromatiales 135613|Chromatiales T low molecular weight - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc DYD1_k127_3807239_0 1026882.MAMP_00270 5.394e-74 259.0 COG3658@1|root,COG3658@2|Bacteria,1PCRS@1224|Proteobacteria,1S5C0@1236|Gammaproteobacteria,463S4@72273|Thiotrichales 72273|Thiotrichales C Cytochrome b/b6/petB - - - - - - - - - - - - Ni_hydr_CYTB DYD1_k127_3807239_2 395019.Bmul_5680 9.719e-45 166.0 COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2VTC8@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 DYD1_k127_381576_0 627192.SLG_34920 1.149e-99 344.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2UNZR@28211|Alphaproteobacteria,2KECI@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_381576_1 1442599.JAAN01000010_gene163 6.929e-66 250.0 COG1948@1|root,COG4880@2|Bacteria,1R9N2@1224|Proteobacteria,1ST9S@1236|Gammaproteobacteria,1X9PG@135614|Xanthomonadales 135614|Xanthomonadales L Beta propeller domain - - - - - - - - - - - - Beta_propel DYD1_k127_381576_2 1452718.JBOY01000136_gene1454 9.772e-22 97.0 COG4339@1|root,COG4339@2|Bacteria,1MZ9X@1224|Proteobacteria,1S59I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - - DYD1_k127_382027_2 1415779.JOMH01000001_gene1474 4.598e-109 361.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales 135614|Xanthomonadales P Heavy metal translocating P-type atpase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS DYD1_k127_382027_4 1415779.JOMH01000001_gene1473 5.207e-37 144.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SYIJ@1236|Gammaproteobacteria,1X7E5@135614|Xanthomonadales 135614|Xanthomonadales K helix_turn_helix, mercury resistance - - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 DYD1_k127_382027_0 521719.ATXQ01000006_gene1329 3.901e-114 383.0 COG5002@1|root,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,1T1I6@1236|Gammaproteobacteria,1YKZA@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Member of a two-component regulatory system cusS GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046688,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071280,GO:0071292,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07636,ko:K07644 ko02020,map02020 M00434,M00452,M00745 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_382027_1 1000565.METUNv1_03135 3.025e-111 363.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2VHHB@28216|Betaproteobacteria,2KVAP@206389|Rhodocyclales 206389|Rhodocyclales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K07665 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_382027_3 1158292.JPOE01000002_gene2704 3.851e-73 249.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VH96@28216|Betaproteobacteria 28216|Betaproteobacteria Q copper-resistance protein, CopA family copA - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD1_k127_3850058_0 395493.BegalDRAFT_2245 1.344e-301 932.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,46047@72273|Thiotrichales 72273|Thiotrichales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_3850058_1 1415779.JOMH01000001_gene2984 1.618e-27 115.0 COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,1SAC6@1236|Gammaproteobacteria,1X7KQ@135614|Xanthomonadales 135614|Xanthomonadales C succinate dehydrogenase - - - - - - - - - - - - Sdh_cyt DYD1_k127_3850058_2 1380394.JADL01000008_gene3742 5.73e-25 108.0 COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,2JTDG@204441|Rhodospirillales 204441|Rhodospirillales C COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt DYD1_k127_3850058_4 4098.XP_009631202.1 1.802e-10 63.0 KOG3245@1|root,KOG3245@2759|Eukaryota,37WZA@33090|Viridiplantae,3GM44@35493|Streptophyta,44MBU@71274|asterids 35493|Streptophyta S Protein of unknown function (DUF1674) - - - - - - - - - - - - DUF1674 DYD1_k127_3850058_3 381666.H16_A1567 4.653e-13 76.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,1K0KG@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the GcvT family ygfZ - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C DYD1_k127_3857973_1 1402135.SUH3_08145 3.428e-42 162.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2TRA7@28211|Alphaproteobacteria,3ZVK2@60136|Sulfitobacter 28211|Alphaproteobacteria C FAD binding domain glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 DYD1_k127_3857973_0 414684.RC1_2148 3.122e-159 512.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,2JPXJ@204441|Rhodospirillales 204441|Rhodospirillales C Cysteine-rich domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 DYD1_k127_3864339_3 768671.ThimaDRAFT_2431 1.08e-50 184.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales 135613|Chromatiales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like DYD1_k127_3864339_2 768671.ThimaDRAFT_2431 8.074e-70 243.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1WXHA@135613|Chromatiales 135613|Chromatiales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like DYD1_k127_3864339_0 713586.KB900536_gene612 6.338e-276 867.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales 135613|Chromatiales D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma DYD1_k127_3864339_4 1026882.MAMP_01645 2.209e-37 151.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,460XC@72273|Thiotrichales 72273|Thiotrichales M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA DYD1_k127_3864339_5 1178482.BJB45_21155 2.118e-07 59.0 COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,1SGEP@1236|Gammaproteobacteria,1XMM6@135619|Oceanospirillales 135619|Oceanospirillales S VanZ like family - - - - - - - - - - - - VanZ DYD1_k127_3864339_1 1158762.KB898043_gene1043 1.13e-108 362.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1WX7U@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b DYD1_k127_3866427_0 627192.SLG_28760 8.158e-79 273.0 COG2175@1|root,COG2175@2|Bacteria,1MVI6@1224|Proteobacteria,2VGYD@28211|Alphaproteobacteria,2KE7J@204457|Sphingomonadales 1224|Proteobacteria C Taurine catabolism dioxygenase TauD, TfdA family MA20_18150 - 1.14.11.17 ko:K03119,ko:K06912 ko00361,ko00430,ko00920,ko01120,ko01220,map00361,map00430,map00920,map01120,map01220 - R05320,R05419,R05493 RC01331,RC01371,RC01372 ko00000,ko00001,ko01000 - - - TauD DYD1_k127_3866427_1 420662.Mpe_A1143 1.177e-43 166.0 2E7KN@1|root,3322N@2|Bacteria,1N6FH@1224|Proteobacteria,2WFF2@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1097) - - - - - - - - - - - - DUF1097 DYD1_k127_3866427_2 1380384.JADN01000006_gene2583 4.873e-23 106.0 COG3751@1|root,COG3751@2|Bacteria,4NZTB@976|Bacteroidetes,1I8H6@117743|Flavobacteriia 976|Bacteroidetes O Prolyl 4-hydroxylase alpha subunit homologues. - - - ko:K07336 - - - - ko00000,ko01000 - - - 2OG-FeII_Oxy_3 DYD1_k127_3866427_3 717773.Thicy_1300 4.358e-17 84.0 2EGSV@1|root,33AIZ@2|Bacteria,1QR3B@1224|Proteobacteria,1RTW3@1236|Gammaproteobacteria,461FI@72273|Thiotrichales 72273|Thiotrichales S Cysteine-rich CPXCG - - - - - - - - - - - - Cys_rich_CPXG DYD1_k127_3887111_2 643867.Ftrac_1934 4.982e-23 106.0 COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47PMC@768503|Cytophagia 976|Bacteroidetes P K -dependent Na Ca exchanger yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD1_k127_3887111_1 653733.Selin_0507 4.014e-35 143.0 COG3137@1|root,COG3137@2|Bacteria 2|Bacteria - - ydiY - - ko:K07283 - - - - ko00000 - - - DUF3078,DUF481 DYD1_k127_3887111_0 1089552.KI911559_gene786 2.383e-153 497.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales 204441|Rhodospirillales E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N DYD1_k127_38964_3 391615.ABSJ01000024_gene255 6.421e-43 158.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1J4PH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - iPC815.YPO1374 Pyr_redox_2 DYD1_k127_38964_1 85643.Tmz1t_1473 8.575e-164 541.0 COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales 206389|Rhodocyclales M Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,Patatin DYD1_k127_38964_0 1121033.AUCF01000003_gene3156 1.19e-168 541.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2JPGU@204441|Rhodospirillales 204441|Rhodospirillales H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.96 ko:K16871 ko00250,ko00650,ko01100,ko01120,map00250,map00650,map01100,map01120 M00027 R10178 RC00008,RC00062 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_3 DYD1_k127_38964_5 75379.Tint_1900 1.713e-19 92.0 COG2350@1|root,COG2350@2|Bacteria,1NHP3@1224|Proteobacteria,2VWVS@28216|Betaproteobacteria 28216|Betaproteobacteria S YCII-related domain - - - ko:K09780 - - - - ko00000 - - - YCII DYD1_k127_38964_2 506534.Rhein_3071 2.316e-46 176.0 COG0346@1|root,COG0346@2|Bacteria,1RHRF@1224|Proteobacteria,1S7BW@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD1_k127_38964_4 1211114.ALIP01000161_gene1626 7.874e-24 109.0 COG3801@1|root,COG3801@2|Bacteria,1QGHR@1224|Proteobacteria,1TDXI@1236|Gammaproteobacteria,1XB55@135614|Xanthomonadales 135614|Xanthomonadales S YjbR - - - - - - - - - - - - YjbR DYD1_k127_38964_6 198467.NP92_04660 6.285e-05 51.0 COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,4HPRP@91061|Bacilli,21VRY@150247|Anoxybacillus 91061|Bacilli J 2'-5' RNA ligase superfamily ytlP - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase DYD1_k127_3902650_2 218851.Aquca_003_00232.1 3.632e-05 53.0 2CXIA@1|root,2RXSU@2759|Eukaryota,37U4U@33090|Viridiplantae,3GAUF@35493|Streptophyta 35493|Streptophyta S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc DYD1_k127_3902650_1 224911.27353560 4.574e-93 316.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria,3JVFH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family MA20_35800 - - - - - - - - - - - DUF2437,FAA_hydrolase DYD1_k127_3902650_0 1207063.P24_03685 4.06e-126 408.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,2JQ7K@204441|Rhodospirillales 204441|Rhodospirillales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD DYD1_k127_390559_1 1042375.AFPL01000056_gene2361 4.393e-37 151.0 COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,467Q6@72275|Alteromonadaceae 1236|Gammaproteobacteria Q COG0500 SAM-dependent methyltransferases yafS - - - - - - - - - - - Methyltransf_11 DYD1_k127_390559_0 377629.TERTU_2108 2.129e-117 391.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,2PMMZ@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M Lysin motif mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD1_k127_390559_2 56107.Cylst_2352 2.296e-26 113.0 COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1G0WY@1117|Cyanobacteria,1HMIN@1161|Nostocales 1117|Cyanobacteria CE Glycine D-amino acid oxidase (deaminating) - - - - - - - - - - - - DAO,Rieske DYD1_k127_3945818_1 1429851.X548_08760 3.616e-126 415.0 COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1X4TN@135614|Xanthomonadales 135614|Xanthomonadales G Xylulose kinase xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N DYD1_k127_3945818_0 380358.XALC_0064 1.422e-200 632.0 COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,1RN5Y@1236|Gammaproteobacteria,1X4B9@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the xylose isomerase family xylA GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - - DYD1_k127_3945818_3 203122.Sde_1512 4.067e-49 182.0 2C388@1|root,30ZIR@2|Bacteria,1RFG7@1224|Proteobacteria,1S4CX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3945818_2 1000565.METUNv1_02392 1.288e-102 340.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VHVH@28216|Betaproteobacteria,2KYIX@206389|Rhodocyclales 206389|Rhodocyclales G PQQ-like domain - - - - - - - - - - - - PQQ DYD1_k127_3947437_1 458817.Shal_0707 8.764e-50 182.0 COG0475@1|root,COG0475@2|Bacteria,1MVGV@1224|Proteobacteria,1RQFR@1236|Gammaproteobacteria,2QERK@267890|Shewanellaceae 1236|Gammaproteobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger DYD1_k127_3947437_0 1218076.BAYB01000012_gene2508 1.585e-106 361.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1K375@119060|Burkholderiaceae 28216|Betaproteobacteria T response regulator zraR - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_3983021_0 1232683.ADIMK_0084 3.437e-137 450.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD1_k127_3992664_2 349124.Hhal_0079 4.552e-118 392.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1X0QS@135613|Chromatiales 135613|Chromatiales C PFAM FAD dependent oxidoreductase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C DYD1_k127_3992664_0 1333998.M2A_0825 8.534e-162 520.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,4BPBI@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_3992664_1 1430440.MGMSRv2_1763 1.47e-128 421.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,2JPD3@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA DYD1_k127_4004442_2 765912.Thimo_2651 1.239e-48 179.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1WX2M@135613|Chromatiales 135613|Chromatiales J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 DYD1_k127_4004442_0 395493.BegalDRAFT_1848 1.897e-121 395.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,4600U@72273|Thiotrichales 72273|Thiotrichales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD1_k127_4004442_1 666685.R2APBS1_1416 1.192e-79 275.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1X32Z@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M DYD1_k127_400826_2 882083.SacmaDRAFT_2658 4.944e-38 149.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_400826_1 1499967.BAYZ01000095_gene4122 2.113e-41 169.0 COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - - DYD1_k127_400826_0 690585.JNNU01000009_gene517 1.581e-175 556.0 COG0028@1|root,COG1012@1|root,COG0028@2|Bacteria,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,4B7AV@82115|Rhizobiaceae 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_402297_1 247639.MGP2080_14756 1.018e-34 142.0 28MV3@1|root,2ZB2R@2|Bacteria,1N53J@1224|Proteobacteria,1SBDN@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF560 DYD1_k127_402297_0 314285.KT71_18381 8.125e-56 203.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RQ7X@1236|Gammaproteobacteria,1J7QP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG1404 Subtilisin-like serine proteases - - - - - - - - - - - - Peptidase_S8 DYD1_k127_4030432_0 1049564.TevJSym_be00270 4.797e-169 555.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J57P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the peptidase S41A family prc GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - BAGE,DUF3340,PDZ,Peptidase_S41 DYD1_k127_4030432_2 1437606.BBOH_0087 1.281e-11 76.0 COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4D0R3@85004|Bifidobacteriales 201174|Actinobacteria T Inner membrane component of T3SS, cytoplasmic domain garA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - - - - - - - - - - FHA,Yop-YscD_cpl,zinc_ribbon_2 DYD1_k127_4030432_1 1121015.N789_07385 1.266e-96 320.0 COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1X3NQ@135614|Xanthomonadales 135614|Xanthomonadales O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA DYD1_k127_4042254_0 392500.Swoo_3788 2.528e-104 351.0 COG3203@1|root,COG3203@2|Bacteria,1R5I5@1224|Proteobacteria,1RM86@1236|Gammaproteobacteria,2Q904@267890|Shewanellaceae 1236|Gammaproteobacteria M PFAM phosphate-selective porin O and P - - - - - - - - - - - - Porin_4,Porin_O_P DYD1_k127_4042254_1 1121405.dsmv_2706 3.169e-84 286.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42Q4I@68525|delta/epsilon subdivisions,2WIX3@28221|Deltaproteobacteria,2MIWV@213118|Desulfobacterales 28221|Deltaproteobacteria E Aminotransferase class-III rocD - 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_4070977_0 314278.NB231_08685 3.192e-172 554.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1WXBI@135613|Chromatiales 135613|Chromatiales S oligopeptide transporter - - - - - - - - - - - - OPT DYD1_k127_4070977_1 587753.EY04_25195 3.095e-40 154.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminotransferase ybdL - 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_4088851_1 1028800.RG540_CH31940 8.436e-150 478.0 COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,2TR6B@28211|Alphaproteobacteria,4B9SF@82115|Rhizobiaceae 28211|Alphaproteobacteria S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_4088851_0 1121028.ARQE01000003_gene839 3.378e-184 578.0 COG1082@1|root,COG1082@2|Bacteria,1MVSJ@1224|Proteobacteria,2TV5J@28211|Alphaproteobacteria,2PJBC@255475|Aurantimonadaceae 28211|Alphaproteobacteria G AP endonuclease family 2 C terminus - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N DYD1_k127_4118287_2 243233.MCA1393 5.741e-62 217.0 COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,1XF7D@135618|Methylococcales 135618|Methylococcales C Thioredoxin-like [2Fe-2S] ferredoxin - - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - 2Fe-2S_thioredx DYD1_k127_4118287_1 795666.MW7_2876 1.182e-234 735.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIGR@28216|Betaproteobacteria,1K3B8@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit fdsB - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Complex1_51K,NADH_4Fe-4S,SLBB DYD1_k127_4118287_0 1026882.MAMP_02771 0.0 1194.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,461VS@72273|Thiotrichales 72273|Thiotrichales C TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD1_k127_416925_0 234267.Acid_5456 1.913e-319 983.0 COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria 57723|Acidobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 DYD1_k127_4192194_2 1267534.KB906759_gene1864 6.27e-08 59.0 2EK74@1|root,33DXH@2|Bacteria,3Y5VZ@57723|Acidobacteria,2JK2Y@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - DYD1_k127_4192194_1 314264.ROS217_14501 1.494e-17 93.0 COG5662@1|root,COG5662@2|Bacteria,1N8DF@1224|Proteobacteria,2UGV4@28211|Alphaproteobacteria,46QKE@74030|Roseovarius 28211|Alphaproteobacteria K AntiSigma factor - - - - - - - - - - - - - DYD1_k127_4192194_0 1453501.JELR01000002_gene1283 3.3e-46 172.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,1S4SX@1236|Gammaproteobacteria,467H4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_4194344_1 497321.C664_06693 8.013e-75 256.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,2KV37@206389|Rhodocyclales 206389|Rhodocyclales O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat - 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans DYD1_k127_4194344_3 765912.Thimo_2091 8.188e-35 135.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1WZ35@135613|Chromatiales 135613|Chromatiales J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a DYD1_k127_4194344_0 572477.Alvin_2221 0.0 1019.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales 135613|Chromatiales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD1_k127_4194344_2 396588.Tgr7_1839 4.228e-38 145.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1WYBV@135613|Chromatiales 135613|Chromatiales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS DYD1_k127_4207304_2 1198452.Jab_2c09850 5.674e-17 82.0 COG0346@1|root,COG0346@2|Bacteria,1RH8Z@1224|Proteobacteria 1224|Proteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD1_k127_4207304_3 1192034.CAP_2637 0.0001919 44.0 COG0346@1|root,COG0346@2|Bacteria,1RH8Z@1224|Proteobacteria,43825@68525|delta/epsilon subdivisions,2X3CB@28221|Deltaproteobacteria,2YVDI@29|Myxococcales 28221|Deltaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD1_k127_4207304_1 1120977.JHUX01000003_gene1570 5.582e-24 107.0 COG0500@1|root,COG2226@2|Bacteria,1RKZF@1224|Proteobacteria,1SIV2@1236|Gammaproteobacteria,3NMGZ@468|Moraxellaceae 1236|Gammaproteobacteria Q O-methyltransferase - - - - - - - - - - - - Methyltransf_31 DYD1_k127_4207304_4 1054213.HMPREF9946_02547 0.0005617 48.0 COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,2U7IF@28211|Alphaproteobacteria,2JTD6@204441|Rhodospirillales 204441|Rhodospirillales S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - DYD1_k127_4207304_0 314345.SPV1_09593 1.401e-46 171.0 2ETWY@1|root,32VZU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4212721_0 1122604.JONR01000007_gene2812 2.35e-94 335.0 COG0841@1|root,COG0841@2|Bacteria,1QXYC@1224|Proteobacteria,1T3KA@1236|Gammaproteobacteria,1XDE0@135614|Xanthomonadales 135614|Xanthomonadales V MMPL family - - - - - - - - - - - - MMPL DYD1_k127_4218668_0 1282876.BAOK01000002_gene10 6.003e-51 189.0 COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2U5AJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 ko:K01935,ko:K02169 ko00780,ko01100,map00780,map01100 M00123,M00572,M00573,M00577 R03182,R09543 RC00003,RC00460,RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 DYD1_k127_4218668_1 1279017.AQYJ01000019_gene1498 5.22e-25 115.0 COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S5WW@1236|Gammaproteobacteria,46CH4@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family - - - - - - - - - - - - DUF4398,OmpA DYD1_k127_4219514_2 1129794.C427_0636 8.933e-166 534.0 2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,4657P@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4219514_1 349521.HCH_02592 1.815e-239 767.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,1XN5T@135619|Oceanospirillales 135619|Oceanospirillales E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 DYD1_k127_4219514_3 1056820.KB900663_gene3783 3.588e-121 400.0 28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,2PMPG@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4219514_0 1049564.TevJSym_aj00060 2.71e-254 811.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1J98N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 DYD1_k127_4219514_6 349521.HCH_02595 2.162e-61 219.0 COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,1S4BU@1236|Gammaproteobacteria,1XPIQ@135619|Oceanospirillales 135619|Oceanospirillales S COG3103 SH3 domain protein - - - - - - - - - - - - OMP_b-brl,SH3_3,SH3_4 DYD1_k127_4219514_5 1049564.TevJSym_aj00080 3.745e-67 235.0 COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,1JADW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl DYD1_k127_4219514_7 1117647.M5M_12200 5e-61 214.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1J6KV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CO Thioredoxin-like resA - - - - - - - - - - - AhpC-TSA,Redoxin DYD1_k127_4219514_8 1121921.KB898712_gene2128 1.714e-24 104.0 2AIDE@1|root,318UT@2|Bacteria,1QJ80@1224|Proteobacteria,1TH62@1236|Gammaproteobacteria,2PP13@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Domain of unknown function (DUF4266) - - - - - - - - - - - - DUF4266 DYD1_k127_4219514_4 1049564.TevJSym_aj00110 2.938e-117 385.0 COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,1J75U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 DYD1_k127_422207_0 1117318.PRUB_11196 4.156e-66 249.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - OMP_b-brl_3,Plug,TonB_dep_Rec DYD1_k127_422207_4 421052.F945_01618 2.782e-05 56.0 COG3712@1|root,COG3712@2|Bacteria,1N28G@1224|Proteobacteria,1RR9M@1236|Gammaproteobacteria,3NJWP@468|Moraxellaceae 1236|Gammaproteobacteria PT Domain of unknown function (DUF4880) - - - ko:K07165 - - - - ko00000 - - - DUF4880,FecR DYD1_k127_422207_3 1298858.AUEL01000018_gene2873 1.343e-18 97.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria,43K4W@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_422207_1 1265503.KB905163_gene2314 2.963e-35 140.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,2Q72B@267889|Colwelliaceae 1236|Gammaproteobacteria CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin DYD1_k127_422207_2 400668.Mmwyl1_2331 1.542e-25 107.0 2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,1XM6K@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4266) - - - - - - - - - - - - DUF4266 DYD1_k127_4245001_3 862908.BMS_3067 1.126e-143 466.0 COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Band 7 protein - - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot DYD1_k127_4245001_5 1201290.M902_1810 1.249e-32 134.0 29X52@1|root,30IU1@2|Bacteria,1N8YP@1224|Proteobacteria,42WWU@68525|delta/epsilon subdivisions,2WT2G@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4245001_0 472759.Nhal_3769 2.136e-281 885.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1WWI3@135613|Chromatiales 135613|Chromatiales L PFAM UvrD REP helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD1_k127_4245001_1 765910.MARPU_04175 6.443e-185 588.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales 135613|Chromatiales P PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD1_k127_4245001_2 396588.Tgr7_0202 5.877e-183 585.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales 135613|Chromatiales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH DYD1_k127_4245001_6 322710.Avin_46510 7.406e-23 101.0 COG3063@1|root,COG3063@2|Bacteria,1N2T8@1224|Proteobacteria,1S9R8@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2 DYD1_k127_4245001_4 1178482.BJB45_15190 1.36e-44 169.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1XK0E@135619|Oceanospirillales 135619|Oceanospirillales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component gtrA - - - - - - - - - - - DctQ DYD1_k127_4245001_7 1120953.AUBH01000010_gene94 5.1e-15 78.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,4642Y@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component gtrB - - - - - - - - - - - DctM DYD1_k127_4277138_2 196367.JNFG01000016_gene4081 1.495e-51 205.0 COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VJ7P@28216|Betaproteobacteria,1JZP6@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 DYD1_k127_4277138_0 58344.JOEL01000022_gene988 2.864e-76 268.0 COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria 201174|Actinobacteria V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - DUF11 DYD1_k127_4277138_4 1121374.KB891575_gene1369 5.631e-06 55.0 COG3637@1|root,COG3637@2|Bacteria,1RK7I@1224|Proteobacteria,1S80S@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety ax21 - - - - - - - - - - - OMP_b-brl DYD1_k127_4277138_1 483219.LILAB_10840 1.287e-56 206.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M peptidylprolyl isomerase, FKBP-type - - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N DYD1_k127_4277138_3 225849.swp_0314 4.114e-48 181.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,2Q8QS@267890|Shewanellaceae 1236|Gammaproteobacteria P PFAM sodium calcium exchanger membrane region - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD1_k127_4291379_1 595460.RRSWK_06362 2.143e-39 153.0 COG1595@1|root,COG1595@2|Bacteria,2IZXS@203682|Planctomycetes 203682|Planctomycetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD1_k127_4291379_2 1121033.AUCF01000027_gene2771 3.593e-36 150.0 COG5012@1|root,COG5012@2|Bacteria,1RJN6@1224|Proteobacteria,2U9SK@28211|Alphaproteobacteria,2JT2Z@204441|Rhodospirillales 204441|Rhodospirillales S B12 binding domain - - - - - - - - - - - - B12-binding DYD1_k127_4291379_0 887062.HGR_05459 1.753e-136 441.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,4AC6Q@80864|Comamonadaceae 28216|Betaproteobacteria M Cyclopropane-fatty-acyl-phospholipid synthase cfa GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS DYD1_k127_4300381_1 1177179.A11A3_08695 4.256e-16 80.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1XK4C@135619|Oceanospirillales 135619|Oceanospirillales MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 DYD1_k127_4300381_0 1469245.JFBG01000019_gene1125 0.0 1191.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales 135613|Chromatiales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS DYD1_k127_4310111_7 1286106.MPL1_11383 1.218e-09 61.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1S87H@1236|Gammaproteobacteria,462T7@72273|Thiotrichales 72273|Thiotrichales T diguanylate cyclase - - - - - - - - - - - - GGDEF DYD1_k127_4310111_2 314278.NB231_06945 1.399e-34 141.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales 135613|Chromatiales EH PFAM Aminotransferase, class IV - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 DYD1_k127_4310111_0 522306.CAP2UW1_1540 3.266e-172 550.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,1KPQW@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_4310111_4 765913.ThidrDRAFT_0396 1.045e-30 123.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1WYUG@135613|Chromatiales 135613|Chromatiales IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD1_k127_4310111_1 90813.JQMT01000001_gene602 5.083e-88 297.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,45ZWN@72273|Thiotrichales 72273|Thiotrichales IQ reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_4310111_5 391615.ABSJ01000050_gene1175 1.029e-23 108.0 COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid DYD1_k127_4310111_3 1415754.JQMK01000006_gene3735 1.295e-32 134.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,467BP@72275|Alteromonadaceae 1236|Gammaproteobacteria U COG2165 Type II secretory pathway, pseudopilin PulG gspG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG DYD1_k127_4310111_6 1195246.AGRI_11807 2.558e-15 86.0 COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,4672W@72275|Alteromonadaceae 1236|Gammaproteobacteria U general secretion pathway protein gspH GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl DYD1_k127_4319040_6 765912.Thimo_1635 1.342e-20 97.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,1WXJG@135613|Chromatiales 135613|Chromatiales L Belongs to the DnaA family. HdA subfamily - - - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA DYD1_k127_4319040_3 626887.J057_23715 1.609e-39 153.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA2 - 2.7.8.41 ko:K08744 ko00564,ko01100,map00564,map01100 - R02030 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD1_k127_4319040_4 745411.B3C1_04680 7.72e-30 133.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1J69V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria VV2512 - - ko:K09938 - - - - ko00000 - - - DUF2066 DYD1_k127_4319040_0 550540.Fbal_1254 3.895e-124 406.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2340 AIRS,AIRS_C DYD1_k127_4319040_5 187272.Mlg_0514 2.339e-23 109.0 COG3147@1|root,COG3147@2|Bacteria,1N9GW@1224|Proteobacteria,1T2WQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 DYD1_k127_4319040_2 187272.Mlg_0825 4.771e-107 348.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,1WW5U@135613|Chromatiales 135613|Chromatiales F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - DCD,dUTPase DYD1_k127_4319040_1 1454004.AW11_01485 5.584e-115 380.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,1KPSS@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA DYD1_k127_4338450_2 1117319.PSPO_01735 1.326e-24 106.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q0SH@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T HAMP domain GGDEF domain EAL - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS_9,dCache_3 DYD1_k127_4338450_3 1122132.AQYH01000001_gene830 3.262e-16 81.0 2EG12@1|root,339T3@2|Bacteria,1NGID@1224|Proteobacteria,2UK0A@28211|Alphaproteobacteria,4BFJ5@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2849) - - - - - - - - - - - - DUF2849 DYD1_k127_4338450_0 1089552.KI911559_gene396 2.397e-228 721.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,2JSH9@204441|Rhodospirillales 204441|Rhodospirillales C Sulfite reductase - - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr DYD1_k127_4338450_1 570952.ATVH01000016_gene2452 4.152e-50 184.0 COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2UDH7@28211|Alphaproteobacteria,2JTNM@204441|Rhodospirillales 204441|Rhodospirillales S Bacterial protein of unknown function (DUF934) - - - - - - - - - - - - DUF934 DYD1_k127_4338450_4 870187.Thini_3955 1.19e-12 78.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - MtrB_PioB,OMP_b-brl,OmpA_membrane DYD1_k127_4339870_0 1121937.AUHJ01000005_gene2350 1.308e-125 407.0 COG2182@1|root,COG2182@2|Bacteria,1MU3H@1224|Proteobacteria,1RY48@1236|Gammaproteobacteria,464R5@72275|Alteromonadaceae 1236|Gammaproteobacteria G Parallel beta-helix repeats - - - - - - - - - - - - - DYD1_k127_4339870_1 1000565.METUNv1_02453 8.446e-13 78.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales 206389|Rhodocyclales T (FHA) domain - - - - - - - - - - - - FHA DYD1_k127_4342860_0 1117318.PRUB_11196 1.013e-96 345.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - OMP_b-brl_3,Plug,TonB_dep_Rec DYD1_k127_4342860_4 1472418.BBJC01000004_gene1789 6.952e-13 75.0 2CBAE@1|root,31814@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4342860_3 1472418.BBJC01000004_gene1790 4.898e-22 103.0 2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4342860_2 697282.Mettu_2234 2.531e-51 201.0 COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales 135618|Methylococcales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_4342860_1 1035191.HMPREF0185_03364 7.764e-57 210.0 2DPYS@1|root,33403@2|Bacteria,1N637@1224|Proteobacteria,2UEN9@28211|Alphaproteobacteria,2KJDU@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - DYD1_k127_4366463_1 204669.Acid345_0637 3.911e-34 138.0 COG1680@1|root,COG1680@2|Bacteria,3Y7EG@57723|Acidobacteria,2JNJ4@204432|Acidobacteriia 204432|Acidobacteriia V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD1_k127_4366463_0 686340.Metal_3811 1.618e-147 473.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XDR0@135618|Methylococcales 135618|Methylococcales J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b DYD1_k127_4366463_2 349124.Hhal_2346 7.981e-12 78.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT DYD1_k127_4368249_0 69395.JQLZ01000002_gene1375 8.822e-76 264.0 COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2TRBF@28211|Alphaproteobacteria,2KIA3@204458|Caulobacterales 28211|Alphaproteobacteria EGP Sugar (and other) transporter - - - ko:K08195 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,Sugar_tr DYD1_k127_4368249_1 313628.LNTAR_09736 3.971e-24 111.0 COG4099@1|root,COG4099@2|Bacteria 2|Bacteria F phospholipase Carboxylesterase - - - - - - - - - - - - Abhydrolase_2,Abhydrolase_8,DLH,Esterase,Peptidase_S9 DYD1_k127_4371377_0 1054213.HMPREF9946_03065 3.367e-58 209.0 COG1028@1|root,COG1028@2|Bacteria,1P1U4@1224|Proteobacteria 1224|Proteobacteria IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 DYD1_k127_438381_0 228410.NE2443 3.346e-47 171.0 COG1463@1|root,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,2VV58@28216|Betaproteobacteria,372SM@32003|Nitrosomonadales 28216|Betaproteobacteria Q Protein of unknown function (DUF3465) - - - - - - - - - - - - DUF3465 DYD1_k127_438381_1 234267.Acid_4171 1.9e-30 127.0 COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria 57723|Acidobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_4401212_0 1044.EH31_05300 3.717e-112 381.0 COG1858@1|root,COG1858@2|Bacteria,1QUP2@1224|Proteobacteria,2TW2M@28211|Alphaproteobacteria,2KCYB@204457|Sphingomonadales 204457|Sphingomonadales P ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS DYD1_k127_4401212_2 1123518.ARWI01000001_gene1913 1.917e-20 101.0 2BKN5@1|root,32F3J@2|Bacteria,1RIMC@1224|Proteobacteria,1S6Q3@1236|Gammaproteobacteria,463R5@72273|Thiotrichales 72273|Thiotrichales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp DYD1_k127_4401212_1 519989.ECTPHS_08598 2.651e-107 364.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1WWVE@135613|Chromatiales 135613|Chromatiales M PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C - - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 DYD1_k127_4401331_0 572477.Alvin_1100 1.41e-212 666.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD1_k127_4401331_2 519989.ECTPHS_12428 3.639e-30 126.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1WYJU@135613|Chromatiales 135613|Chromatiales S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX DYD1_k127_4401331_1 713586.KB900536_gene30 5.102e-155 493.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1WW13@135613|Chromatiales 135613|Chromatiales L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD1_k127_4406925_0 886293.Sinac_1154 9.885e-111 372.0 COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_4409653_0 472759.Nhal_0500 0.0 1119.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD1_k127_4409653_7 572477.Alvin_0145 2.375e-36 142.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1WW2I@135613|Chromatiales 135613|Chromatiales HL Thiamine monophosphate synthase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,NUDIX_4,TMP-TENI DYD1_k127_4409653_5 472759.Nhal_3851 9.776e-51 191.0 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1WWH6@135613|Chromatiales 135613|Chromatiales D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity zapD - - ko:K18778 - - - - ko00000,ko03036 - - - ZapD DYD1_k127_4409653_4 305700.B447_07584 1.693e-51 192.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KW4Z@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE DYD1_k127_4409653_3 323261.Noc_0310 5.025e-93 315.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1WW7R@135613|Chromatiales 135613|Chromatiales NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue - - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 DYD1_k127_4409653_2 472759.Nhal_3848 5.682e-158 507.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1WWAB@135613|Chromatiales 135613|Chromatiales U Type II secretion system - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF DYD1_k127_4409653_1 519989.ECTPHS_01969 5.092e-227 717.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N DYD1_k127_4409653_6 1121921.KB898706_gene2722 5.431e-50 182.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2PNZB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria NU Pilin (bacterial filament) pilA - - ko:K02650,ko:K02655 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD1_k127_442596_1 1095769.CAHF01000010_gene1336 1.702e-37 161.0 COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria,472VF@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 DYD1_k127_442596_0 396588.Tgr7_2392 1.804e-53 194.0 COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,1S35N@1236|Gammaproteobacteria,1WX7F@135613|Chromatiales 135613|Chromatiales M polysaccharide export protein - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB DYD1_k127_442596_2 572477.Alvin_1786 1.013e-21 101.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,1WWGP@135613|Chromatiales 135613|Chromatiales M Polysaccharide chain length determinant protein - - - - - - - - - - - - GNVR,Wzz DYD1_k127_4444985_0 195250.CM001776_gene3588 4.094e-121 396.0 COG0037@1|root,COG0037@2|Bacteria,1G2S7@1117|Cyanobacteria 1117|Cyanobacteria D Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system - - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 DYD1_k127_4444985_1 614083.AWQR01000001_gene3031 9.799e-52 199.0 COG0515@1|root,COG0745@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria 28216|Betaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K11912,ko:K12132 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - HAMP,Pkinase DYD1_k127_4444985_2 194439.CT0537 0.0001442 49.0 COG3427@1|root,COG3427@2|Bacteria,1FFPW@1090|Chlorobi 1090|Chlorobi S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc DYD1_k127_4446451_0 1185876.BN8_03291 2.713e-44 165.0 COG2162@1|root,COG2162@2|Bacteria,4NPEY@976|Bacteroidetes,47QTB@768503|Cytophagia 976|Bacteroidetes Q Belongs to the arylamine N-acetyltransferase family nat - 2.3.1.118 ko:K00675 - - - - ko00000,ko01000 - - - Acetyltransf_2 DYD1_k127_4446451_1 697282.Mettu_2234 4.476e-41 168.0 COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales 135618|Methylococcales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_4449010_0 1027273.GZ77_06745 1.946e-121 400.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,1XI36@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the citrate synthase family prpC - 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - - Citrate_synt DYD1_k127_4449010_1 349124.Hhal_1072 1.553e-116 385.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,1WWC7@135613|Chromatiales 135613|Chromatiales G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - - PEP_mutase DYD1_k127_4449010_2 1123242.JH636434_gene3747 7.973e-54 192.0 COG2079@1|root,COG2079@2|Bacteria,2IYP0@203682|Planctomycetes 203682|Planctomycetes S PFAM MmgE PrpD family - - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD DYD1_k127_4461992_4 1415780.JPOG01000001_gene3035 1.761e-13 74.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1X61Y@135614|Xanthomonadales 135614|Xanthomonadales NU pilus assembly protein pilp pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP DYD1_k127_4461992_2 1123257.AUFV01000003_gene1056 2.986e-53 194.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1X4H8@135614|Xanthomonadales 135614|Xanthomonadales NU Pilus assembly protein, PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO DYD1_k127_4461992_3 545264.KB898746_gene827 2.868e-40 155.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales 135613|Chromatiales NU PFAM Fimbrial assembly - - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN DYD1_k127_4461992_1 1122604.JONR01000010_gene3934 4.825e-110 366.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1X3US@135614|Xanthomonadales 135614|Xanthomonadales NU Pilus assembly protein pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 DYD1_k127_4461992_0 225937.HP15_473 3.354e-146 487.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,464YC@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG5009 Membrane carboxypeptidase penicillin-binding protein mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase DYD1_k127_4474769_4 3659.XP_004136780.1 1.009e-07 59.0 COG0666@1|root,KOG4177@2759|Eukaryota,37HMP@33090|Viridiplantae,3GD8Q@35493|Streptophyta,4JJAB@91835|fabids 35493|Streptophyta M Ankyrin repeat and protein kinase domain-containing protein 1-like - GO:0002262,GO:0002376,GO:0002520,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006887,GO:0006888,GO:0006996,GO:0007010,GO:0007163,GO:0007275,GO:0008092,GO:0008093,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010638,GO:0012505,GO:0014731,GO:0015672,GO:0016020,GO:0016043,GO:0016192,GO:0016323,GO:0016528,GO:0016529,GO:0018130,GO:0019438,GO:0019899,GO:0030011,GO:0030016,GO:0030017,GO:0030018,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030424,GO:0030507,GO:0030673,GO:0030674,GO:0030863,GO:0031252,GO:0031253,GO:0031256,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032589,GO:0032940,GO:0033013,GO:0033014,GO:0033036,GO:0033043,GO:0033267,GO:0034101,GO:0034613,GO:0034641,GO:0035088,GO:0035090,GO:0042383,GO:0042592,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0044237,GO:0044249,GO:0044271,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045197,GO:0045199,GO:0045202,GO:0045211,GO:0046483,GO:0046903,GO:0046907,GO:0048193,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048731,GO:0048821,GO:0048856,GO:0048869,GO:0048872,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0051117,GO:0051128,GO:0051130,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0060090,GO:0061245,GO:0061515,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0097060,GO:0097458,GO:0098590,GO:0098771,GO:0098794,GO:0099080,GO:0099081,GO:0099512,GO:0099568,GO:0120025,GO:0120038,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1990778 - ko:K21440 - - - - ko00000,ko04131 - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5,Motile_Sperm DYD1_k127_4474769_1 1122197.ATWI01000010_gene1128 6.949e-65 225.0 COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,1S45S@1236|Gammaproteobacteria,466EC@72275|Alteromonadaceae 1236|Gammaproteobacteria P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex bfr - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin DYD1_k127_4474769_3 1007104.SUS17_1296 5.287e-09 59.0 COG2906@1|root,COG2906@2|Bacteria 2|Bacteria P 2 iron, 2 sulfur cluster binding bfd GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - ko:K02192 - - - - ko00000 - - - Fer2_BFD DYD1_k127_4474769_0 398525.KB900701_gene4497 2.835e-88 306.0 COG3391@1|root,COG3391@2|Bacteria,1MXRF@1224|Proteobacteria,2U1E9@28211|Alphaproteobacteria,3JTTY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - NHL DYD1_k127_4474769_2 1036674.A28LD_1821 3.304e-20 91.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RZ1Y@1236|Gammaproteobacteria,2QGM3@267893|Idiomarinaceae 1236|Gammaproteobacteria P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD1_k127_4488359_1 1236959.BAMT01000015_gene2842 7.111e-36 148.0 COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2VHGN@28216|Betaproteobacteria,2KNEV@206350|Nitrosomonadales 206350|Nitrosomonadales GP SMP-30/Gluconolaconase/LRE-like region - - - - - - - - - - - - SGL DYD1_k127_4488359_0 373994.Riv7116_3289 6.569e-68 252.0 COG2133@1|root,COG2133@2|Bacteria,1G39K@1117|Cyanobacteria,1HR5R@1161|Nostocales 1117|Cyanobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH DYD1_k127_449388_3 1123261.AXDW01000001_gene1237 2.521e-59 209.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1X3MZ@135614|Xanthomonadales 135614|Xanthomonadales F Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS DYD1_k127_449388_1 765910.MARPU_13455 1.061e-64 228.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales 135613|Chromatiales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N DYD1_k127_449388_2 83406.HDN1F_08570 6.259e-62 222.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1J4TW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ DYD1_k127_449388_0 1415779.JOMH01000001_gene3092 3.034e-202 639.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1X3EG@135614|Xanthomonadales 135614|Xanthomonadales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD1_k127_4497349_5 1163409.UUA_00625 4.361e-39 151.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XDAY@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type multidrug transport system, ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_4497349_2 666685.R2APBS1_2791 1.48e-106 355.0 COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RP16@1236|Gammaproteobacteria,1X5W0@135614|Xanthomonadales 135614|Xanthomonadales M Biotin-lipoyl like - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 DYD1_k127_4497349_4 1304275.C41B8_10605 2.183e-47 178.0 COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,1RQQB@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator ybiH GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043254,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2001141 - - - - - - - - - - DUF1956,TetR_N DYD1_k127_4497349_3 1340493.JNIF01000003_gene3476 8.315e-64 242.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus moxJ - - ko:K06867 - - - - ko00000 - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5,SBP_bac_3 DYD1_k127_4497349_1 243090.RB598 3.449e-107 362.0 COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_4497349_0 234267.Acid_5827 7.154e-154 504.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_4515567_1 690850.Desaf_0933 1.201e-62 231.0 2DN8B@1|root,32W2U@2|Bacteria,1R03I@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_4515567_0 551275.KB899545_gene2489 2.659e-212 673.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,43WGJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N DYD1_k127_4517377_0 396588.Tgr7_0463 4.28e-217 705.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales 135613|Chromatiales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE DYD1_k127_4517377_6 1385515.N791_07955 1.599e-18 87.0 COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1X821@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria VL23_05015 - - - - - - - - - - - zf-CHCC DYD1_k127_4517377_1 472759.Nhal_3503 1.682e-121 397.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,1X02A@135613|Chromatiales 135613|Chromatiales F Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose hldD - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase DYD1_k127_4517377_2 1122139.KB907864_gene1987 1.311e-112 374.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,1RMBF@1236|Gammaproteobacteria,1XHQ9@135619|Oceanospirillales 135619|Oceanospirillales M heptosyltransferase waaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_4517377_4 1500890.JQNL01000001_gene561 1.169e-46 182.0 COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,1X40C@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position kdkA - 2.7.1.166 ko:K11211 ko00540,map00540 - R09767 RC00002,RC00078 ko00000,ko00001,ko01000 - - - Kdo DYD1_k127_4517377_3 396588.Tgr7_0480 7.902e-70 247.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1WVUX@135613|Chromatiales 135613|Chromatiales M Lipid A biosynthesis lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD1_k127_4517377_5 225937.HP15_3828 2.07e-43 164.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,4682Y@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria IV02_27405 - - - - - - - - - - - YkuD DYD1_k127_4525291_4 400682.PAC_15706423 4.009e-06 57.0 COG0666@1|root,KOG4177@2759|Eukaryota,39MBZ@33154|Opisthokonta,3BWUR@33208|Metazoa 33154|Opisthokonta M Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_4 DYD1_k127_4525291_3 1085623.GNIT_2803 6.652e-39 153.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,464BN@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD1_k127_4525291_1 1283300.ATXB01000001_gene1848 6.328e-87 298.0 COG4772@1|root,COG4772@2|Bacteria,1MXJU@1224|Proteobacteria,1T2PY@1236|Gammaproteobacteria,1XH14@135618|Methylococcales 135618|Methylococcales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_4531263_0 1201293.AKXQ01000011_gene3473 1.127e-208 668.0 COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,1MU1B@1224|Proteobacteria,1SYHX@1236|Gammaproteobacteria 1236|Gammaproteobacteria C reductase chain B - - - ko:K07307 ko00920,map00920 - R09501 RC02555 ko00000,ko00001,ko02000 5.A.3.3 - - DmsC,Fer4_11,Fer4_4 DYD1_k127_4531263_1 637905.SVI_2713 8.098e-23 98.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,2QEU3@267890|Shewanellaceae 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_4535383_1 1267535.KB906767_gene766 2.898e-42 161.0 COG0551@1|root,COG0551@2|Bacteria,3Y7FR@57723|Acidobacteria 57723|Acidobacteria L Protein of unknown function (DUF1595) - - - - - - - - - - - - PSCyt3,PSD2,PSD3,PSD4,PSD5 DYD1_k127_4535383_0 627192.SLG_31400 1.298e-97 334.0 COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_4535383_3 1267535.KB906767_gene4320 1.035e-30 135.0 COG0491@1|root,COG0491@2|Bacteria,3Y48F@57723|Acidobacteria,2JIRT@204432|Acidobacteriia 204432|Acidobacteriia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_4535383_2 886293.Sinac_1155 8.644e-33 136.0 COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes 203682|Planctomycetes S Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_4 DYD1_k127_460999_0 1121918.ARWE01000001_gene3651 3.95e-125 411.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,42NEF@68525|delta/epsilon subdivisions,2WIVI@28221|Deltaproteobacteria,43U26@69541|Desulfuromonadales 28221|Deltaproteobacteria C NADH:flavin oxidoreductase / NADH oxidase family - - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN DYD1_k127_460999_1 63737.Npun_F5723 3.051e-39 153.0 28JPA@1|root,2Z9FC@2|Bacteria,1G2DB@1117|Cyanobacteria,1HQP9@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_4616417_3 713587.THITH_10455 2.839e-73 253.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales 135613|Chromatiales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD1_k127_4616417_2 765914.ThisiDRAFT_1080 6.199e-99 334.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1WW47@135613|Chromatiales 135613|Chromatiales J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 DYD1_k127_4616417_1 1026882.MAMP_03024 2.329e-124 402.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,45ZPM@72273|Thiotrichales 72273|Thiotrichales E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD1_k127_4616417_0 237609.PSAKL28_41120 5.939e-262 834.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 DYD1_k127_4616417_4 1033802.SSPSH_001089 6.324e-49 180.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the transferase hexapeptide repeat family dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0158 Hexapep,Hexapep_2,THDPS_N_2 DYD1_k127_4616417_5 314230.DSM3645_25844 7.535e-13 68.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2IYK8@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase DYD1_k127_4619828_3 748280.NH8B_0143 3.122e-40 156.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KU4J@206351|Neisseriales 206351|Neisseriales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 DYD1_k127_4619828_0 1122604.JONR01000043_gene3174 2.465e-140 453.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1X3XQ@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM DYD1_k127_4619828_4 105559.Nwat_0986 6.676e-35 143.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1WWVF@135613|Chromatiales 135613|Chromatiales S Competence protein - - - - - - - - - - - - Pribosyltran DYD1_k127_4619828_1 472759.Nhal_0761 1.001e-90 307.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1WWA7@135613|Chromatiales 135613|Chromatiales H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD1_k127_4619828_2 1123253.AUBD01000005_gene193 2.864e-83 280.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1X42Y@135614|Xanthomonadales 135614|Xanthomonadales L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HHH_5,Helicase_C,RecG_wedge DYD1_k127_4624521_2 1207063.P24_11280 9.915e-58 211.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales 204441|Rhodospirillales EP Belongs to the ABC transporter superfamily oppD - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY DYD1_k127_4624521_1 1207063.P24_11275 1.032e-132 437.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2TT4V@28211|Alphaproteobacteria,2JPUT@204441|Rhodospirillales 204441|Rhodospirillales EP N-terminal TM domain of oligopeptide transport permease C - - - - - - - - - - - - BPD_transp_1,OppC_N DYD1_k127_4624521_0 1207063.P24_11270 7.48e-138 445.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR3F@28211|Alphaproteobacteria,2JQU0@204441|Rhodospirillales 204441|Rhodospirillales EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 DYD1_k127_463753_2 926566.Terro_0573 2.613e-08 56.0 COG1721@1|root,COG1721@2|Bacteria,3Y5XW@57723|Acidobacteria,2JMDZ@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 DYD1_k127_463753_0 926566.Terro_0574 4.363e-74 274.0 COG1240@1|root,COG1240@2|Bacteria,3Y655@57723|Acidobacteria,2JKRA@204432|Acidobacteriia 204432|Acidobacteriia H Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - - - - - - - - - - - DYD1_k127_463753_1 639030.JHVA01000001_gene1285 2.97e-16 89.0 COG0497@1|root,COG0497@2|Bacteria,3Y6KC@57723|Acidobacteria,2JME0@204432|Acidobacteriia 204432|Acidobacteriia L DNA recombination - - - - - - - - - - - - - DYD1_k127_4655495_1 717772.THIAE_01770 2.319e-80 276.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,4600A@72273|Thiotrichales 72273|Thiotrichales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD1_k127_4655495_7 391615.ABSJ01000042_gene2258 1.076e-22 103.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX DYD1_k127_4655495_4 765912.Thimo_2553 7.537e-59 209.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1WX8T@135613|Chromatiales 135613|Chromatiales K Belongs to the UPF0301 (AlgH) family - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 DYD1_k127_4655495_6 159087.Daro_3908 1.434e-23 111.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,2KUYN@206389|Rhodocyclales 206389|Rhodocyclales M COG0810 Periplasmic protein TonB, links inner and outer membranes - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD1_k127_4655495_2 396588.Tgr7_2906 9.279e-63 229.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WX7A@135613|Chromatiales 135613|Chromatiales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE DYD1_k127_4655495_0 765911.Thivi_3308 4.877e-122 399.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1WVY1@135613|Chromatiales 135613|Chromatiales HJ Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N DYD1_k127_4655495_3 396588.Tgr7_2904 3.126e-61 217.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1WY6S@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02657 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg DYD1_k127_4655495_5 519989.ECTPHS_03869 5.437e-37 141.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1WYZY@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg DYD1_k127_4661745_1 1227739.Hsw_PA0213 8.523e-21 102.0 COG2865@1|root,COG2865@2|Bacteria,4NRX4@976|Bacteroidetes,47X00@768503|Cytophagia 976|Bacteroidetes K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 DYD1_k127_4661745_0 1266914.ATUK01000014_gene2067 7.19e-130 419.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales 135613|Chromatiales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD1_k127_4663818_1 1517416.IDAT_08145 5.336e-42 165.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,2QF3F@267893|Idiomarinaceae 1236|Gammaproteobacteria O Peptidase family M48 Z012_09445 - - - - - - - - - - - Peptidase_M48 DYD1_k127_4663818_0 1123366.TH3_11570 4.838e-67 240.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,2TV4M@28211|Alphaproteobacteria,2JT8B@204441|Rhodospirillales 204441|Rhodospirillales C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD DYD1_k127_4663818_2 203119.Cthe_2456 1.824e-12 73.0 arCOG06471@1|root,32BPX@2|Bacteria,1VD13@1239|Firmicutes,24M2I@186801|Clostridia 186801|Clostridia S MTH538 TIR-like domain (DUF1863) - - - - - - - - - - - - DUF1863 DYD1_k127_4672867_1 323848.Nmul_A1208 5.74e-26 115.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,372UU@32003|Nitrosomonadales 28216|Betaproteobacteria CO oxidoreductase DsbE dsbE - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin DYD1_k127_4672867_0 864051.BurJ1DRAFT_2538 1.701e-114 381.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,1KIYF@119065|unclassified Burkholderiales 28216|Betaproteobacteria O cytochrome C ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD1_k127_4676615_0 1049564.TevJSym_be00170 5.401e-126 413.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1J4F8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N DYD1_k127_4676615_3 519989.ECTPHS_02199 2.07e-43 164.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1WYG6@135613|Chromatiales 135613|Chromatiales M Belongs to the ompA family - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD1_k127_4676615_4 472759.Nhal_0185 6.61e-36 146.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales 135613|Chromatiales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri,YfiO DYD1_k127_4676615_1 1123253.AUBD01000010_gene2159 3.58e-90 301.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1X4FR@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM DYD1_k127_4676615_2 1123392.AQWL01000005_gene2938 2.182e-59 210.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,1KS0G@119069|Hydrogenophilales 119069|Hydrogenophilales F Queuosine biosynthesis protein QueC - - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC DYD1_k127_4707930_2 1502724.FF80_01531 1.273e-17 83.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,3N6ED@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N DYD1_k127_4707930_0 1286106.MPL1_06999 6.663e-90 301.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,4604Q@72273|Thiotrichales 72273|Thiotrichales D TIGRFAM Cell division ATP-binding protein FtsE - - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran DYD1_k127_4707930_1 713586.KB900536_gene1800 1.327e-50 199.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1WWEB@135613|Chromatiales 135613|Chromatiales D Part of the ABC transporter FtsEX involved in cellular division - - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX DYD1_k127_4712518_1 290397.Adeh_2925 1.363e-63 224.0 COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,42Q7W@68525|delta/epsilon subdivisions,2WKZ8@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - 2.4.1.212 ko:K00752,ko:K11936 ko02026,map02026 - - - ko00000,ko00001,ko01000,ko01003,ko02000 4.D.1.1.10,4.D.1.1.2,4.D.1.1.3,4.D.1.1.4,4.D.1.1.5 GT2 - Glyco_tranf_2_3,Glycos_transf_2 DYD1_k127_4712518_0 338963.Pcar_2791 1.625e-158 521.0 COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,42PMY@68525|delta/epsilon subdivisions,2WPU5@28221|Deltaproteobacteria,43SS0@69541|Desulfuromonadales 28221|Deltaproteobacteria G Polysaccharide deacetylase - - - ko:K11931 ko02026,map02026 - - - ko00000,ko00001,ko01000 - - - Polysacc_deac_1 DYD1_k127_4719175_0 1123279.ATUS01000001_gene689 2.595e-170 550.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1RMA1@1236|Gammaproteobacteria,1J5I1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E transport system, periplasmic component - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 DYD1_k127_4719175_2 1123279.ATUS01000001_gene688 6.301e-144 467.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,1RNUH@1236|Gammaproteobacteria,1J5J2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component yejE - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 DYD1_k127_4719175_1 1123279.ATUS01000001_gene687 3.038e-152 487.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,1RMH8@1236|Gammaproteobacteria,1J6DT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P transport system, permease component yejB - - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 DYD1_k127_4719175_3 1211114.ALIP01000022_gene2407 5.326e-45 165.0 COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,1X3M6@135614|Xanthomonadales 135614|Xanthomonadales C NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH DYD1_k127_47355_0 330214.NIDE3051 6.318e-22 100.0 COG0745@1|root,COG0745@2|Bacteria 330214.NIDE3051|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_47355_1 1173025.GEI7407_1016 1.32e-13 81.0 COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - CHASE3,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_4742049_4 511062.GU3_01035 7.079e-38 162.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1Y3KC@135624|Aeromonadales 135624|Aeromonadales E homoserine dehydrogenase metL - 1.1.1.3,2.7.2.4 ko:K12525 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Homoserine_dh,NAD_binding_3 DYD1_k127_4742049_0 454957.IA64_10560 2.327e-132 443.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1X541@135614|Xanthomonadales 135614|Xanthomonadales E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N DYD1_k127_4742049_6 1029823.AFIE01000028_gene3254 3.329e-06 57.0 COG0551@1|root,COG0551@2|Bacteria,1PZFI@1224|Proteobacteria,1RQ64@1236|Gammaproteobacteria,3NKDD@468|Moraxellaceae 1236|Gammaproteobacteria L Nuclease-related domain - - - - - - - - - - - - NERD,zf-C4_Topoisom DYD1_k127_4742049_1 1442599.JAAN01000046_gene2710 8.781e-89 303.0 COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1X3N8@135614|Xanthomonadales 135614|Xanthomonadales L Preprotein translocase subunit TatD tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase DYD1_k127_4742049_2 1121448.DGI_0782 2.527e-42 168.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,42V1Y@68525|delta/epsilon subdivisions,2WRE9@28221|Deltaproteobacteria,2MC8Z@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 DYD1_k127_4742049_5 700598.Niako_2492 1.965e-31 136.0 2EA99@1|root,334DQ@2|Bacteria,4P45M@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_4742049_3 751994.AGIG01000028_gene1591 1.735e-41 156.0 COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,1J4BZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF2333 DYD1_k127_4749059_3 1158165.KB898871_gene2361 4.352e-14 74.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1WXBH@135613|Chromatiales 135613|Chromatiales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc DYD1_k127_4749059_1 469371.Tbis_3159 1.474e-34 138.0 COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,4E5H0@85010|Pseudonocardiales 201174|Actinobacteria K helix_turn_helix multiple antibiotic resistance protein pecS - - - - - - - - - - - MarR,MarR_2 DYD1_k127_4749059_0 1184607.AUCHE_22_00900 1.042e-165 531.0 COG0372@1|root,COG0372@2|Bacteria,2GSH4@201174|Actinobacteria,4F62W@85018|Dermatophilaceae 201174|Actinobacteria C Citrate synthase, C-terminal domain gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD1_k127_4749059_2 237368.SCABRO_01641 3.682e-22 110.0 COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,2IYQF@203682|Planctomycetes 203682|Planctomycetes M Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD1_k127_475074_1 1469613.JT55_19340 7.941e-103 344.0 COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2TQRM@28211|Alphaproteobacteria,3FDF3@34008|Rhodovulum 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase vdlC GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - - - - - - - - - - adh_short DYD1_k127_475074_2 1122604.JONR01000017_gene4315 3.752e-43 161.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1X6GE@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N DYD1_k127_475074_0 2340.JV46_17430 4.043e-248 771.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1J56Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 ATP-synt_ab,ATP-synt_ab_N DYD1_k127_475074_3 187272.Mlg_2870 1.641e-36 139.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1WW4K@135613|Chromatiales 135613|Chromatiales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt DYD1_k127_4757987_0 287.DR97_328 2.3e-322 1005.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1YISC@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P AcrB/AcrD/AcrF family helA - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran DYD1_k127_4757987_1 522373.Smlt0037 7.792e-118 396.0 COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,1RP9Q@1236|Gammaproteobacteria,1X2Y3@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - HlyD_D23 DYD1_k127_4757987_2 1415780.JPOG01000001_gene2758 1.063e-12 71.0 COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1RPC5@1236|Gammaproteobacteria,1X5QB@135614|Xanthomonadales 135614|Xanthomonadales MU Outer membrane efflux protein - - - ko:K15725 - - - - ko00000,ko02000 1.B.17.2.2 - - OEP DYD1_k127_4775845_4 1255043.TVNIR_3549 3.484e-79 269.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1WWXG@135613|Chromatiales 135613|Chromatiales L PFAM HNH endonuclease - - - - - - - - - - - - HNH_5 DYD1_k127_4775845_7 1101195.Meth11DRAFT_0869 1.341e-10 69.0 2DNXA@1|root,32ZMW@2|Bacteria,1NBF6@1224|Proteobacteria,2W848@28216|Betaproteobacteria,2KNW4@206350|Nitrosomonadales 206350|Nitrosomonadales S Protein of unknown function (DUF3106) - - - - - - - - - - - - DUF3106 DYD1_k127_4775845_8 1163409.UUA_07365 5.748e-09 63.0 2A0FJ@1|root,30NJD@2|Bacteria,1QBAA@1224|Proteobacteria,1T6UX@1236|Gammaproteobacteria,1X87D@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD1_k127_4775845_5 1131269.AQVV01000058_gene1682 4.092e-38 151.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation sigE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_4775845_0 713586.KB900536_gene2408 8.477e-205 661.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales 135613|Chromatiales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII DYD1_k127_4775845_1 349124.Hhal_2416 1.247e-176 575.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales 135613|Chromatiales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d DYD1_k127_4775845_6 713587.THITH_01975 1.031e-18 94.0 COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SWTF@1236|Gammaproteobacteria,1WZTX@135613|Chromatiales 135613|Chromatiales D Sporulation related domain - - - - - - - - - - - - SPOR DYD1_k127_4775845_2 1123073.KB899241_gene2690 7.052e-107 364.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1X5SE@135614|Xanthomonadales 135614|Xanthomonadales T Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_4775845_3 765914.ThisiDRAFT_2492 4.118e-96 325.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 DYD1_k127_4778253_0 357808.RoseRS_0010 9.704e-100 350.0 COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia 32061|Chloroflexia U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 DYD1_k127_4778253_2 1353276.JADR01000003_gene2756 2.321e-05 57.0 COG1874@1|root,COG3291@1|root,COG3391@1|root,COG4412@1|root,COG4447@1|root,COG1874@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia 976|Bacteroidetes O cellulase activity - - - - - - - - - - - - CUB,MAM,PA,TSP_3,fn3 DYD1_k127_4778253_1 1485545.JQLW01000010_gene1494 5.556e-12 79.0 COG3391@1|root,COG3391@2|Bacteria,1QYUP@1224|Proteobacteria 1224|Proteobacteria EH HYR domain - - - - - - - - - - - - HYR DYD1_k127_4788241_1 543913.D521_1159 2.746e-53 194.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,1KQCZ@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate DYD1_k127_4788241_0 748280.NH8B_1377 0.0 1104.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KQCR@206351|Neisseriales 206351|Neisseriales C Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase DYD1_k127_4794825_4 1396141.BATP01000059_gene2547 0.0001356 53.0 2AYZ8@1|root,31R54@2|Bacteria,46WP8@74201|Verrucomicrobia 1396141.BATP01000059_gene2547|- - - - - - - - - - - - - - - - DYD1_k127_4794825_1 1323663.AROI01000006_gene2873 2.514e-75 260.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1392 Phosphate transport regulator (distant homolog of PhoU) UF78_21250 - - ko:K07220 - - - - ko00000 - - - PhoU_div DYD1_k127_4794825_0 713586.KB900536_gene1261 1.46e-163 524.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1WX8S@135613|Chromatiales 135613|Chromatiales P PFAM phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 DYD1_k127_4794825_2 411901.BACCAC_02264 1.359e-68 244.0 COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,2FP8M@200643|Bacteroidia,4AM6K@815|Bacteroidaceae 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran DYD1_k127_4794825_3 411477.PARMER_02670 4.404e-17 97.0 COG1277@1|root,COG1277@2|Bacteria,4NI5T@976|Bacteroidetes,2FNVZ@200643|Bacteroidia,22W2G@171551|Porphyromonadaceae 976|Bacteroidetes E ABC-type transport system involved in multi-copper enzyme maturation permease component - - - - - - - - - - - - Peptidase_M1 DYD1_k127_4819925_2 1541065.JRFE01000026_gene2123 2.449e-18 96.0 COG0491@1|root,COG0491@2|Bacteria,1GNN3@1117|Cyanobacteria,3VNCV@52604|Pleurocapsales 1117|Cyanobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_4819925_0 247633.GP2143_17731 2.364e-137 454.0 COG3209@1|root,COG3209@2|Bacteria,1NPW7@1224|Proteobacteria 1224|Proteobacteria M Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS DYD1_k127_4819925_1 1123504.JQKD01000010_gene2561 1.668e-42 164.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,4AB1X@80864|Comamonadaceae 28216|Betaproteobacteria O Glutathione S-transferase gst8 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_C_3,GST_C_4,GST_N_3 DYD1_k127_4834514_2 1121015.N789_06785 1.144e-12 78.0 COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,1RPRK@1236|Gammaproteobacteria,1X2XM@135614|Xanthomonadales 135614|Xanthomonadales E peptidase - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,PD40,Peptidase_S9 DYD1_k127_4834514_1 627192.SLG_25140 4.6e-24 113.0 2EVK9@1|root,33P0C@2|Bacteria,1NDYB@1224|Proteobacteria,2UQHZ@28211|Alphaproteobacteria,2K9N4@204457|Sphingomonadales 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4834514_0 1000565.METUNv1_01183 7.008e-44 166.0 COG4520@1|root,COG4520@2|Bacteria,1RIHU@1224|Proteobacteria,2VTAT@28216|Betaproteobacteria 28216|Betaproteobacteria M Glycine zipper - - - - - - - - - - - - 17kDa_Anti_2,Rick_17kDa_Anti DYD1_k127_4842982_1 391937.NA2_02814 1.943e-77 266.0 28MZG@1|root,2ZB66@2|Bacteria,1R6ZF@1224|Proteobacteria,2U3DX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S OsmC-like protein - - - - - - - - - - - - OsmC DYD1_k127_4842982_0 377629.TERTU_0102 3.906e-165 524.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,1RPMX@1236|Gammaproteobacteria,2PPGS@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria E Oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N DYD1_k127_4860194_3 1245471.PCA10_47800 6.31e-10 64.0 2BJ2U@1|root,32DBN@2|Bacteria,1QF10@1224|Proteobacteria,1TC1X@1236|Gammaproteobacteria,1YJNU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - EthD DYD1_k127_4860194_0 713586.KB900536_gene2015 1.685e-111 372.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales 135613|Chromatiales G PFAM Glucose Sorbosone dehydrogenase - - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH DYD1_k127_4860194_1 1448139.AI20_07195 9.567e-92 312.0 COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1N2YQ@1224|Proteobacteria,1RPR3@1236|Gammaproteobacteria 1236|Gammaproteobacteria FL Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ada - 2.1.1.63 ko:K00567,ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,HTH_18,Methyltransf_1N DYD1_k127_4860194_2 1121101.HMPREF1532_03458 1.817e-77 267.0 COG2755@1|root,COG2755@2|Bacteria,4NHBT@976|Bacteroidetes,2G2NP@200643|Bacteroidia,4AMWH@815|Bacteroidaceae 976|Bacteroidetes E COG2755 Lysophospholipase L1 and related - - - - - - - - - - - - Lipase_GDSL_2 DYD1_k127_4860194_4 452637.Oter_2862 1.952e-06 52.0 COG0457@1|root,COG0457@2|Bacteria 452637.Oter_2862|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_4869095_1 1007104.SUS17_2461 3.17e-11 65.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales 204457|Sphingomonadales G glucose sorbosone - - - - - - - - - - - - GSDH DYD1_k127_4869095_0 382464.ABSI01000011_gene3094 1.482e-202 640.0 COG0388@1|root,COG0388@2|Bacteria,46ZGG@74201|Verrucomicrobia,2IUQ5@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Carbon-nitrogen hydrolase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase DYD1_k127_4869936_6 1217658.F987_03625 3.721e-15 83.0 2ANH8@1|root,31DG0@2|Bacteria,1P4S2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_4869936_5 1249627.D779_4021 6.64e-17 88.0 2DJGJ@1|root,32UD0@2|Bacteria,1R9Z5@1224|Proteobacteria,1SIBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4869936_3 861299.J421_1876 1.656e-63 231.0 COG3386@1|root,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD1_k127_4869936_4 1472418.BBJC01000004_gene1788 1.642e-20 103.0 2CBAE@1|root,31814@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4869936_2 1123060.JONP01000015_gene4411 2.371e-68 241.0 COG3618@1|root,COG3618@2|Bacteria,1R5V9@1224|Proteobacteria,2TU5F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S metal-dependent hydrolase of the TIM-barrel fold - - - - - - - - - - - - Amidohydro_2 DYD1_k127_4869936_0 1245469.S58_25900 3.539e-124 412.0 COG2271@1|root,COG2271@2|Bacteria,1MUEK@1224|Proteobacteria,2TS60@28211|Alphaproteobacteria,3JR21@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Major Facilitator Superfamily - - - ko:K13021 - - - - ko00000,ko02000 2.A.1.14.3 - - MFS_1 DYD1_k127_4869936_1 1282876.BAOK01000002_gene221 8.391e-107 356.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,4BTBE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria CG PQQ enzyme repeat - - 1.1.9.1 ko:K17760 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD1_k127_4885759_0 575540.Isop_2778 2.344e-79 281.0 COG1519@1|root,COG1519@2|Bacteria,2IYCJ@203682|Planctomycetes 203682|Planctomycetes M transferase - - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N DYD1_k127_4885759_1 446470.Snas_6367 2.257e-63 231.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4EY23@85014|Glycomycetales 201174|Actinobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GAF,GGDEF DYD1_k127_4896567_2 1046724.KB889908_gene927 1.248e-63 222.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,464JX@72275|Alteromonadaceae 1236|Gammaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 Pribosyl_synth,Pribosyltran_N DYD1_k127_4896567_4 1230343.CANP01000037_gene2673 1.785e-11 74.0 COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,1JC5E@118969|Legionellales 118969|Legionellales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB - - ko:K02494 - - - - ko00000 - - - LolB DYD1_k127_4896567_1 765910.MARPU_03590 2.983e-64 242.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales 135613|Chromatiales U Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 DYD1_k127_4896567_0 391615.ABSJ01000019_gene81 2.469e-87 297.0 COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,1J5SF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel mscS - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix DYD1_k127_4896567_3 675812.VHA_001690 4.112e-27 118.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XTF3@135623|Vibrionales 135623|Vibrionales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD1_k127_4934935_0 1463921.JODF01000002_gene3096 1.801e-23 118.0 COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria 201174|Actinobacteria F WD-40 repeat - - - - - - - - - - - - HTH_31,WD40 DYD1_k127_4934935_1 1454202.PPBDW_100292___1 0.000804 53.0 COG4935@1|root,COG4935@2|Bacteria,1RCIN@1224|Proteobacteria,1S3H9@1236|Gammaproteobacteria,1XUZF@135623|Vibrionales 135623|Vibrionales O Proprotein convertase P-domain - - - - - - - - - - - - P_proprotein,Peptidase_M36 DYD1_k127_4971840_1 237368.SCABRO_03896 8.143e-72 248.0 COG2095@1|root,COG2095@2|Bacteria,2J2AQ@203682|Planctomycetes 203682|Planctomycetes U MarC family integral membrane protein - - - - - - - - - - - - MarC DYD1_k127_4971840_0 266117.Rxyl_0206 5.474e-149 484.0 COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4CR1A@84995|Rubrobacteria 84995|Rubrobacteria F PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_1 DYD1_k127_4981158_0 234267.Acid_1734 2.829e-261 831.0 COG0612@1|root,COG0612@2|Bacteria,3Y2UB@57723|Acidobacteria 57723|Acidobacteria S PFAM Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_4991890_0 405948.SACE_2794 9.203e-103 341.0 COG1024@1|root,COG1024@2|Bacteria,2IBBD@201174|Actinobacteria,4E1DE@85010|Pseudonocardiales 201174|Actinobacteria I Enoyl-CoA hydratase/isomerase - - 4.1.2.41,4.2.1.101 ko:K18383 ko00360,ko01100,ko01110,map00360,map01100,map01110 - R05772,R05773 RC00307,RC01468,RC01828 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_4991890_1 765912.Thimo_1960 6.879e-94 315.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,1WXC7@135613|Chromatiales 135613|Chromatiales S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH DYD1_k127_4991890_4 566466.NOR53_677 2.917e-43 167.0 COG0526@1|root,COG0526@2|Bacteria,1N6UU@1224|Proteobacteria,1SEIM@1236|Gammaproteobacteria,1J8D8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Thioredoxin_2 DYD1_k127_4991890_5 1089551.KE386572_gene2348 1.126e-37 150.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,4BQ4Z@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S SOS response associated peptidase (SRAP) MA20_42060 - - - - - - - - - - - SRAP DYD1_k127_4991890_3 1353529.M899_2851 4.49e-58 209.0 COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,42T5R@68525|delta/epsilon subdivisions,2WX1F@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def_2 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD1_k127_4991890_6 1296990.H845_1325 7.391e-10 71.0 COG3258@1|root,COG3258@2|Bacteria,1NGZH@1224|Proteobacteria,2TYZ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD1_k127_4991890_2 1082931.KKY_351 1.997e-64 238.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3N88K@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria G PQQ-like domain - - 1.1.2.8,1.1.9.1 ko:K00114,ko:K17760 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD1_k127_5017140_1 627192.SLG_31400 4.501e-104 354.0 COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_5017140_0 886293.Sinac_1153 1.005e-164 546.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_5027115_0 396588.Tgr7_1188 6.705e-298 924.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1WWU3@135613|Chromatiales 135613|Chromatiales C UPF0313 protein - - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N DYD1_k127_5027115_7 497964.CfE428DRAFT_2119 4.556e-25 115.0 COG2755@1|root,COG2755@2|Bacteria,46SSC@74201|Verrucomicrobia 74201|Verrucomicrobia E PFAM lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 DYD1_k127_5027115_6 1463900.JOIX01000034_gene3989 1.028e-45 174.0 COG2910@1|root,COG2910@2|Bacteria,2GK2P@201174|Actinobacteria 201174|Actinobacteria S NADH-flavin reductase - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 DYD1_k127_5027115_5 1122939.ATUD01000007_gene2098 1.5e-116 381.0 COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria,4CPK1@84995|Rubrobacteria 84995|Rubrobacteria G HAD-superfamily hydrolase, subfamily IIA - - - ko:K02566 - - - - ko00000 - - - Hydrolase_6,Hydrolase_like DYD1_k127_5027115_3 497964.CfE428DRAFT_0657 1.136e-156 508.0 COG0686@1|root,COG0686@2|Bacteria,46S7U@74201|Verrucomicrobia 74201|Verrucomicrobia E Alanine dehydrogenase/PNT, C-terminal domain ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N DYD1_k127_5027115_4 644107.SL1157_0788 3.973e-119 406.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,4NB3E@97050|Ruegeria 28211|Alphaproteobacteria P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD1_k127_5027115_1 1208321.D104_11805 2.444e-260 817.0 COG0754@1|root,COG3942@1|root,COG0754@2|Bacteria,COG3942@2|Bacteria,1MW6V@1224|Proteobacteria,1RQAP@1236|Gammaproteobacteria,1XHKB@135619|Oceanospirillales 135619|Oceanospirillales E Glutathionylspermidine synthase - - 3.5.1.78,6.3.1.8 ko:K01460 ko00480,ko01100,map00480,map01100 - R01917,R01918 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CHAP,GSP_synth DYD1_k127_5027115_2 926550.CLDAP_16270 5.904e-214 676.0 COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria 2|Bacteria K acetyltransferase yhcX - - ko:K11206 - - - - ko00000,ko01000 - - - Acetyltransf_1,CN_hydrolase DYD1_k127_5036504_0 59196.RICGR_0428 9.719e-164 527.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1JD5F@118969|Legionellales 118969|Legionellales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C DYD1_k127_5036504_1 1158182.KB905031_gene2451 9.996e-46 171.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1WYD2@135613|Chromatiales 135613|Chromatiales J binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N DYD1_k127_5036504_2 1255043.TVNIR_3258 3.215e-08 63.0 2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1RY97@1236|Gammaproteobacteria,1WXMV@135613|Chromatiales 135613|Chromatiales S membrane - - - - - - - - - - - - DUF2232 DYD1_k127_5046828_1 1223545.GS4_43_00260 7.276e-34 140.0 COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria,4GABG@85026|Gordoniaceae 201174|Actinobacteria I Serine aminopeptidase, S33 ytpA GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 DYD1_k127_5046828_2 526227.Mesil_2545 1.725e-31 128.0 COG5485@1|root,COG5485@2|Bacteria 2|Bacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL DYD1_k127_5046828_0 1219035.NT2_07_01960 2.698e-72 259.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria,2K1GK@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_5058377_1 404380.Gbem_1265 3.01e-53 192.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,43TBU@69541|Desulfuromonadales 28221|Deltaproteobacteria E Belongs to the alpha-IPM synthase homocitrate synthase family cimA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer DYD1_k127_5058377_2 1336208.JADY01000010_gene3318 2.032e-12 75.0 COG1846@1|root,COG1846@2|Bacteria,1NBQR@1224|Proteobacteria,2UGT1@28211|Alphaproteobacteria 28211|Alphaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - HTH_27,MarR DYD1_k127_5058377_0 768671.ThimaDRAFT_3789 9.078e-174 550.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,1RP3W@1236|Gammaproteobacteria,1WVXS@135613|Chromatiales 135613|Chromatiales C decarboxylase beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta DYD1_k127_5074328_3 314278.NB231_00885 7.394e-24 106.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1WWYX@135613|Chromatiales 135613|Chromatiales E TIGRFAM lysine 2,3-aminomutase YodO family protein - - 5.4.3.2 ko:K01843,ko:K19810 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000,ko03012 - - - Fer4_12,Fer4_14,Radical_SAM DYD1_k127_5074328_0 713587.THITH_13100 2.922e-97 320.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1WX8C@135613|Chromatiales 135613|Chromatiales J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD1_k127_5074328_1 1249627.D779_1436 1.747e-88 305.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1WW5X@135613|Chromatiales 135613|Chromatiales J Elongation factor P--(R)-beta-lysine ligase - - - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 DYD1_k127_5074328_2 1283300.ATXB01000001_gene322 8.05e-67 236.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1XE6R@135618|Methylococcales 135618|Methylococcales I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase DYD1_k127_5088862_1 886377.Murru_1948 3.401e-50 180.0 COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HXEI@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD1_k127_5088862_2 1202768.JROF01000019_gene2940 2.223e-19 97.0 arCOG08934@1|root,arCOG08934@2157|Archaea 2157|Archaea S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD1_k127_5088862_0 1346791.M529_19040 9.024e-154 494.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales 204457|Sphingomonadales CG Dehydrogenase - - 1.1.9.1,1.17.2.2 ko:K17760,ko:K21676 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD1_k127_5106086_1 234267.Acid_5046 1.238e-27 113.0 2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria 2|Bacteria S Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159 DYD1_k127_5106086_0 883080.HMPREF9697_02192 1.891e-93 321.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,3JX83@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_5107040_1 1156919.QWC_17307 1.656e-32 139.0 COG1917@1|root,COG1917@2|Bacteria,1RH8X@1224|Proteobacteria,2VSGV@28216|Betaproteobacteria,3T7PX@506|Alcaligenaceae 28216|Betaproteobacteria S conserved protein, contains double-stranded beta-helix domain - - - - - - - - - - - - Cupin_2 DYD1_k127_5107040_0 118168.MC7420_1111 2.971e-72 252.0 COG0300@1|root,COG0300@2|Bacteria,1G1Z0@1117|Cyanobacteria,1H9PX@1150|Oscillatoriales 1117|Cyanobacteria S KR domain - - - - - - - - - - - - adh_short DYD1_k127_5107040_2 1220535.IMCC14465_11430 1.663e-17 95.0 COG0760@1|root,COG0760@2|Bacteria,1NNJD@1224|Proteobacteria 1224|Proteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 DYD1_k127_5115075_1 1265313.HRUBRA_02020 9.711e-22 100.0 COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,1RMZE@1236|Gammaproteobacteria,1J66U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H COG3201 Nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter DYD1_k127_5115075_0 247634.GPB2148_1538 1.012e-79 279.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T239@1236|Gammaproteobacteria,1J4TJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_5121009_1 1205680.CAKO01000006_gene3271 3.173e-48 176.0 COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein possibly involved in utilization of glycolate and propanediol - - - - - - - - - - - - Haem_degrading DYD1_k127_5121009_5 91464.S7335_4107 3.712e-07 57.0 COG0737@1|root,COG0834@1|root,COG3391@1|root,COG4222@1|root,COG0737@2|Bacteria,COG0834@2|Bacteria,COG3391@2|Bacteria,COG4222@2|Bacteria,1G0YK@1117|Cyanobacteria,1GYWT@1129|Synechococcus 1117|Cyanobacteria F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C,DUF4214,Exo_endo_phos,HemolysinCabind,Phytase-like DYD1_k127_5121009_4 555793.WSK_2874 5.757e-09 63.0 2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_5121009_0 59538.XP_005981185.1 1.036e-104 359.0 2CMC3@1|root,2QPXZ@2759|Eukaryota,38CYT@33154|Opisthokonta 33154|Opisthokonta G feruloyl esterase activity faeB-1 GO:0000272,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010393,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0016998,GO:0017144,GO:0030600,GO:0042737,GO:0042802,GO:0042803,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0045488,GO:0045490,GO:0045491,GO:0045493,GO:0046983,GO:0052689,GO:0071554,GO:0071704,GO:1901575 3.1.1.73 ko:K09252 - - - - ko00000,ko01000 - - - Tannase DYD1_k127_5121009_3 1123377.AUIV01000009_gene2683 4.24e-11 73.0 COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S3GK@1236|Gammaproteobacteria,1X75M@135614|Xanthomonadales 135614|Xanthomonadales T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl DYD1_k127_5121009_2 1101195.Meth11DRAFT_1463 8.292e-16 81.0 28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2W82N@28216|Betaproteobacteria,2KNHR@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - DYD1_k127_5127203_2 225937.HP15_3363 7.865e-66 227.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4664R@72275|Alteromonadaceae 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD1_k127_5127203_0 518766.Rmar_1656 1.261e-277 878.0 COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Belongs to the Orn Lys Arg decarboxylase class-II family - - 2.7.2.4,4.1.1.20 ko:K00928,ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC DYD1_k127_5127203_4 745411.B3C1_15679 3.029e-21 96.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1J619@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186 PRA-CH,PRA-PH DYD1_k127_5127203_1 1234364.AMSF01000016_gene1667 5.15e-110 361.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1X39D@135614|Xanthomonadales 135614|Xanthomonadales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD1_k127_5127203_3 913325.N799_11980 3.088e-63 224.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1X3ZJ@135614|Xanthomonadales 135614|Xanthomonadales E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD1_k127_5132399_0 1267535.KB906767_gene473 3.963e-87 299.0 28JXN@1|root,30T38@2|Bacteria,3Y61P@57723|Acidobacteria 57723|Acidobacteria S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS DYD1_k127_5132399_1 1298867.AUES01000001_gene1607 1.841e-48 181.0 COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,3JQU4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NHL repeat - - - - - - - - - - - - NHL DYD1_k127_5134953_2 1158760.AQXP01000034_gene2194 1.204e-06 58.0 COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SGPC@1236|Gammaproteobacteria,1WYNC@135613|Chromatiales 135613|Chromatiales T PFAM Anti sigma-E protein RseA - - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_N DYD1_k127_5134953_0 523791.Kkor_0747 3.037e-74 255.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1XJAY@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the sigma-70 factor family. ECF subfamily algU - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_5134953_1 631362.Thi970DRAFT_00483 1.721e-16 81.0 COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1WZ6Q@135613|Chromatiales 135613|Chromatiales S Flavinator of succinate dehydrogenase - - - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 DYD1_k127_515736_0 1442599.JAAN01000043_gene480 1.033e-172 554.0 COG3661@1|root,COG3661@2|Bacteria,1MXKA@1224|Proteobacteria,1RP0V@1236|Gammaproteobacteria,1X5RV@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the glycosyl hydrolase 67 family aguA - 3.2.1.139 ko:K01235 - - - - ko00000,ko01000 - - - Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N DYD1_k127_515736_1 396588.Tgr7_3156 2.312e-91 312.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales 135613|Chromatiales G PFAM Glucose Sorbosone dehydrogenase - - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH DYD1_k127_5201828_1 748247.AZKH_1140 4.402e-09 59.0 COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,2W0DD@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function(DUF2779) - - - - - - - - - - - - DUF2779 DYD1_k127_5201828_0 555793.WSK_1442 4.039e-13 78.0 28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,2UKQP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5221620_0 565045.NOR51B_1828 2.675e-116 383.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1J4QN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009436,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:1901575 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iECSF_1327.ECSF_2799,iECW_1372.ECW_m3242,iEKO11_1354.EKO11_0745,iJN746.PP_0356,iWFL_1372.ECW_m3242 Malate_synthase DYD1_k127_5221620_2 1454004.AW11_01567 1.453e-67 240.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria 28216|Betaproteobacteria S aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD1_k127_5221620_3 382464.ABSI01000002_gene4321 8.967e-61 214.0 COG2080@1|root,COG2080@2|Bacteria,46VAB@74201|Verrucomicrobia,2IVP1@203494|Verrucomicrobiae 203494|Verrucomicrobiae C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 DYD1_k127_5221620_1 1121374.KB891586_gene2542 4.158e-77 269.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD1_k127_5222324_0 1123242.JH636434_gene3999 3.871e-116 387.0 COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes 203682|Planctomycetes M CotH kinase protein - - - - - - - - - - - - CotH DYD1_k127_5222324_1 1267535.KB906767_gene4988 4.546e-85 291.0 2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria 57723|Acidobacteria S Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159 DYD1_k127_5222324_3 234267.Acid_1337 5.801e-46 178.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - ko:K03088 - - - - ko00000,ko03021 - - - Glyoxalase DYD1_k127_5222324_4 583355.Caka_1703 2.222e-44 181.0 2C37Z@1|root,33NYZ@2|Bacteria,46UEA@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - DYD1_k127_5222324_2 583355.Caka_1702 1.518e-84 290.0 COG1131@1|root,COG1131@2|Bacteria,46V0T@74201|Verrucomicrobia,3K9MC@414999|Opitutae 414999|Opitutae V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5222324_5 1121904.ARBP01000001_gene5806 2.648e-19 95.0 COG1595@1|root,COG1595@2|Bacteria,4NMJ7@976|Bacteroidetes,47PC1@768503|Cytophagia 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_5222324_6 314285.KT71_02912 1.827e-11 72.0 2EFI3@1|root,339AJ@2|Bacteria,1N96F@1224|Proteobacteria,1SE0P@1236|Gammaproteobacteria,1J9XG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 DYD1_k127_5242207_0 396588.Tgr7_2629 9.567e-117 387.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE DYD1_k127_5242207_3 1109445.AGSX01000172_gene1081 3.576e-45 171.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1Z155@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind DYD1_k127_5242207_2 1121939.L861_17665 2.154e-54 204.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1XHNM@135619|Oceanospirillales 135619|Oceanospirillales C Part of a membrane complex involved in electron transport rnfE - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr DYD1_k127_5242207_1 1158146.KB907126_gene1609 5.518e-90 299.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1WW35@135613|Chromatiales 135613|Chromatiales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD DYD1_k127_524567_2 525257.HMPREF0204_13941 1.307e-08 60.0 COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,1HYKF@117743|Flavobacteriia,3ZNKG@59732|Chryseobacterium 976|Bacteroidetes P Putative esterase - - - ko:K07214 - - - - ko00000 - - - CBM_48,Esterase DYD1_k127_524567_0 400668.Mmwyl1_2779 2.758e-147 481.0 COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria,1XIBN@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the mannitol dehydrogenase family - - 1.1.1.57 ko:K00040 ko00040,ko01100,map00040,map01100 M00061 R02454 RC00085 ko00000,ko00001,ko00002,ko01000 - - - Mannitol_dh,Mannitol_dh_C DYD1_k127_524567_1 382464.ABSI01000006_gene798 3.066e-147 471.0 COG4146@1|root,COG4146@2|Bacteria,46UV3@74201|Verrucomicrobia,2ITNB@203494|Verrucomicrobiae 2|Bacteria S Sodium:solute symporter family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF DYD1_k127_5259105_0 589865.DaAHT2_1509 7.07e-112 380.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,42PQI@68525|delta/epsilon subdivisions,2WKZR@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp DYD1_k127_5259105_1 1303518.CCALI_00052 9.335e-69 237.0 COG0041@1|root,COG0041@2|Bacteria 2|Bacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - iETEC_1333.ETEC_0575,iJN746.PP_5336,iPC815.YPO3076,iUTI89_1310.UTI89_C0551 AIRC DYD1_k127_5259105_2 637389.Acaty_c0667 3.186e-45 171.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,2NCKQ@225057|Acidithiobacillales 225057|Acidithiobacillales S Putative modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD DYD1_k127_5269575_2 1082933.MEA186_13912 8.672e-53 190.0 COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2TU6K@28211|Alphaproteobacteria,43HZT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S FAD dependent oxidoreductase - - - - - - - - - - - - DAO DYD1_k127_5269575_0 1288826.MSNKSG1_18115 9.289e-93 317.0 COG0438@1|root,COG0438@2|Bacteria,1PDW1@1224|Proteobacteria,1RZIK@1236|Gammaproteobacteria,469U7@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_5269575_1 1384054.N790_06425 8.35e-90 309.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,1X3BA@135614|Xanthomonadales 135614|Xanthomonadales H Outer membrane receptor proteins mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD1_k127_5270159_1 743299.Acife_0049 1.26e-47 175.0 COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria 1224|Proteobacteria L PFAM NUDIX hydrolase - - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N_2 DYD1_k127_5270159_0 306281.AJLK01000102_gene3405 2.191e-55 201.0 COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria 1117|Cyanobacteria S MOSC domain - - - - - - - - - - - - - DYD1_k127_5270159_2 270374.MELB17_10988 6.231e-14 74.0 COG0500@1|root,COG2226@2|Bacteria,1QU8Z@1224|Proteobacteria,1RS1E@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 DYD1_k127_528090_1 1168065.DOK_03303 4.852e-27 122.0 COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S1WE@1236|Gammaproteobacteria,1J73M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_528090_0 1469245.JFBG01000019_gene1106 3.494e-124 402.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1WVYK@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD DYD1_k127_5281342_5 187272.Mlg_0334 8.298e-100 332.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1WW2P@135613|Chromatiales 135613|Chromatiales D Reduces the stability of FtsZ polymers in the presence of ATP zapE - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase DYD1_k127_5281342_6 1384056.N787_03855 1.972e-97 327.0 COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,1RXYM@1236|Gammaproteobacteria,1X3GY@135614|Xanthomonadales 135614|Xanthomonadales E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase DYD1_k127_5281342_0 84531.JMTZ01000038_gene3596 0.0 1302.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1X46R@135614|Xanthomonadales 135614|Xanthomonadales E glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N DYD1_k127_5281342_4 575540.Isop_1724 1.333e-105 348.0 COG0588@1|root,COG0588@2|Bacteria 2|Bacteria G phosphoglycerate mutase activity gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 DYD1_k127_5281342_7 159087.Daro_2740 3.206e-54 195.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,2KW50@206389|Rhodocyclales 206389|Rhodocyclales S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - - - - - - - - - - Hexapep DYD1_k127_5281342_2 1265505.ATUG01000002_gene1318 2.203e-112 379.0 COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,42U9J@68525|delta/epsilon subdivisions,2WQ39@28221|Deltaproteobacteria 28221|Deltaproteobacteria EGP Uncharacterised MFS-type transporter YbfB - - - ko:K05548,ko:K05819,ko:K08195 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,MFS_4 DYD1_k127_5281342_3 1121015.N789_04875 4.076e-107 354.0 COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,1RPFI@1236|Gammaproteobacteria,1X38E@135614|Xanthomonadales 135614|Xanthomonadales I Acyl-CoA thioesterase tesB - - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 DYD1_k127_5281342_1 402881.Plav_2894 2.874e-123 401.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,1JNGY@119043|Rhodobiaceae 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MA20_25935 - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_5281342_8 247633.GP2143_13486 1.812e-16 89.0 COG0510@1|root,COG0510@2|Bacteria,1MVBB@1224|Proteobacteria,1SYBV@1236|Gammaproteobacteria,1JBYJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M choline kinase involved in LPS biosynthesis - - - - - - - - - - - - APH DYD1_k127_5284476_0 1150626.PHAMO_10277 9.096e-107 353.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2JPSX@204441|Rhodospirillales 204441|Rhodospirillales M NmrA-like family dfrA - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase DYD1_k127_5284476_1 1163409.UUA_16013 3.966e-64 230.0 COG3407@1|root,COG3407@2|Bacteria,1N5EZ@1224|Proteobacteria,1S19T@1236|Gammaproteobacteria,1X9HF@135614|Xanthomonadales 135614|Xanthomonadales I GHMP kinases N terminal domain - - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_N DYD1_k127_5285642_1 314278.NB231_11719 1.583e-12 68.0 COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,1RZY2@1236|Gammaproteobacteria,1X091@135613|Chromatiales 135613|Chromatiales M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3 DYD1_k127_5285642_0 395493.BegalDRAFT_1206 2.682e-34 149.0 COG4969@1|root,COG4969@2|Bacteria,1N1CZ@1224|Proteobacteria,1SAKN@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Belongs to the N-Me-Phe pilin family - - - - - - - - - - - - Pilin DYD1_k127_5303905_0 1089550.ATTH01000001_gene1792 6.155e-223 703.0 COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1FJ0A@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2 DYD1_k127_5303905_1 580332.Slit_0466 6.278e-51 187.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,44VMW@713636|Nitrosomonadales 28216|Betaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase DYD1_k127_5310853_3 1408418.JNJH01000029_gene2418 1.045e-06 55.0 COG0346@1|root,COG0346@2|Bacteria,1MZQY@1224|Proteobacteria 1224|Proteobacteria E bleomycin resistance protein - - - - - - - - - - - - Glyoxalase DYD1_k127_5310853_4 290317.Cpha266_2281 0.0001524 52.0 COG1357@1|root,COG1357@2|Bacteria 2|Bacteria S protein homooligomerization - - - - - - - - - - - - DUF1566 DYD1_k127_5310853_2 1209072.ALBT01000032_gene2092 5.628e-29 122.0 2CK8Q@1|root,31PVK@2|Bacteria,1RIRH@1224|Proteobacteria,1SD2E@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5310853_0 1323663.AROI01000014_gene85 4.485e-77 277.0 COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,1T3IW@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_5321634_2 765912.Thimo_0732 1.332e-80 284.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales 135613|Chromatiales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB DYD1_k127_5321634_0 1304883.KI912532_gene2596 2.059e-92 310.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KV6X@206389|Rhodocyclales 206389|Rhodocyclales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep DYD1_k127_5321634_3 754476.Q7A_1139 3.137e-46 171.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,460QN@72273|Thiotrichales 72273|Thiotrichales I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA DYD1_k127_5321634_1 1384054.N790_06620 2.313e-90 308.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1X2Y9@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD DYD1_k127_5324060_1 1282876.BAOK01000001_gene3591 7.016e-27 112.0 COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,2TUIS@28211|Alphaproteobacteria,4BSNG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N DYD1_k127_5324060_3 1282876.BAOK01000001_gene3591 6.946e-18 86.0 COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,2TUIS@28211|Alphaproteobacteria,4BSNG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N DYD1_k127_5324060_0 159087.Daro_1297 9.178e-73 254.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2VQ52@28216|Betaproteobacteria 28216|Betaproteobacteria L uracil-DNA glycosylase - - - - - - - - - - - - DUF488,UDG DYD1_k127_5324060_2 1123377.AUIV01000005_gene1687 3.167e-18 90.0 COG3818@1|root,COG3818@2|Bacteria,1Q5R3@1224|Proteobacteria,1RWBA@1236|Gammaproteobacteria,1X331@135614|Xanthomonadales 135614|Xanthomonadales S acetyltransferase - - - ko:K06977 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_5343512_8 397948.Cmaq_0334 3.278e-20 100.0 COG0179@1|root,arCOG00235@2157|Archaea,2XQQH@28889|Crenarchaeota 28889|Crenarchaeota Q PFAM fumarylacetoacetate (FAA) hydrolase - - - - - - - - - - - - FAA_hydrolase DYD1_k127_5343512_5 1026882.MAMP_02154 1.863e-55 199.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,1S7KX@1236|Gammaproteobacteria,463K7@72273|Thiotrichales 72273|Thiotrichales S protein conserved in bacteria - - - ko:K09966 - - - - ko00000 - - - DUF2237 DYD1_k127_5343512_7 1223521.BBJX01000001_gene1022 5.19e-51 187.0 COG4106@1|root,COG4106@2|Bacteria,1QZC8@1224|Proteobacteria,2WHJN@28216|Betaproteobacteria,4AJYU@80864|Comamonadaceae 28216|Betaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 DYD1_k127_5343512_2 420324.KI912007_gene8867 4.755e-85 286.0 COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,2TS58@28211|Alphaproteobacteria,1JR35@119045|Methylobacteriaceae 28211|Alphaproteobacteria O PFAM Glutathione S-transferase domain gstch8 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 DYD1_k127_5343512_6 1123279.ATUS01000001_gene926 2.575e-53 203.0 COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria,1J62A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria FJ COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE DYD1_k127_5343512_4 1122599.AUGR01000010_gene981 4.234e-60 218.0 28RZD@1|root,2ZEBA@2|Bacteria,1RBEH@1224|Proteobacteria,1RP8T@1236|Gammaproteobacteria,1XIH6@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - DYD1_k127_5343512_1 1033802.SSPSH_002230 1.413e-164 529.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_4420,iYL1228.KPN_04135 Hexapep,Hexapep_2,NTP_transf_3 DYD1_k127_5343512_0 1122604.JONR01000017_gene4318 1.345e-204 647.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1X43R@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS DYD1_k127_5343512_3 1304275.C41B8_08430 5.561e-74 250.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - - - - - - - - - - - GATase_6,SIS DYD1_k127_5359115_1 631454.N177_0581 6.96e-39 147.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,1JNH5@119043|Rhodobiaceae 28211|Alphaproteobacteria P Sodium:sulfate symporter transmembrane region sdcS - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C DYD1_k127_5372122_0 1121935.AQXX01000131_gene2793 4.789e-225 709.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1XIWM@135619|Oceanospirillales 135619|Oceanospirillales L DNA helicase recQ1 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind DYD1_k127_5373535_1 1122137.AQXF01000003_gene1981 1.55e-129 422.0 COG1629@1|root,COG4771@2|Bacteria,1QUWS@1224|Proteobacteria,2U2GG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,STN,TonB_dep_Rec DYD1_k127_5373535_0 1089547.KB913013_gene2808 9.25e-165 529.0 COG0738@1|root,COG0738@2|Bacteria,4NHI6@976|Bacteroidetes,47KNG@768503|Cytophagia 976|Bacteroidetes G PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_5374299_5 1122603.ATVI01000006_gene499 6.289e-62 216.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1X3SF@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretory pathway, component HofQ pilQ - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N DYD1_k127_5374299_6 1005999.GLGR_3336 1.335e-49 184.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI DYD1_k127_5374299_2 1397528.Q671_16230 2.341e-123 405.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1XH38@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase DYD1_k127_5374299_1 396588.Tgr7_3031 5.221e-144 467.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc DYD1_k127_5374299_4 686340.Metal_1547 1.742e-76 263.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XEBB@135618|Methylococcales 135618|Methylococcales F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase DYD1_k127_5374299_3 1313172.YM304_38950 8.647e-90 311.0 COG2733@1|root,COG2733@2|Bacteria,2GKGM@201174|Actinobacteria 201174|Actinobacteria M membrane - - - - - - - - - - - - DUF445 DYD1_k127_5374299_0 767434.Fraau_2434 6.843e-206 652.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales 135614|Xanthomonadales IQ Activates fatty acids by binding to coenzyme A rpfB - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD1_k127_5379445_0 627192.SLG_26430 3.087e-36 138.0 2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_5379445_2 1335760.ASTG01000003_gene1750 6.087e-21 102.0 28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5379445_1 136993.KB900627_gene391 3.412e-30 124.0 2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5380034_0 1168065.DOK_01449 0.0 1077.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_540516_7 1452718.JBOY01000048_gene1109 7.154e-26 113.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Transport Permease Protein yadH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD1_k127_540516_1 1301098.PKB_3520 3.816e-120 394.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter yadG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_540516_5 1429851.X548_16325 2.459e-60 216.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1X4YF@135614|Xanthomonadales 135614|Xanthomonadales S Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 DYD1_k127_540516_8 204669.Acid345_4162 9.217e-21 99.0 COG1438@1|root,COG1438@2|Bacteria,3Y551@57723|Acidobacteria,2JJTA@204432|Acidobacteriia 204432|Acidobacteriia K Regulates arginine biosynthesis genes argR - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C DYD1_k127_540516_0 518766.Rmar_0950 6.33e-123 407.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1FJVB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Belongs to the argininosuccinate synthase family. Type 1 subfamily argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth DYD1_k127_540516_2 215803.DB30_7506 3.803e-85 296.0 COG0132@1|root,COG0132@2|Bacteria,1MYAE@1224|Proteobacteria,438QP@68525|delta/epsilon subdivisions,2X92A@28221|Deltaproteobacteria,2YXIK@29|Myxococcales 28221|Deltaproteobacteria H Domain of unknown function (DUF1611_C) P-loop domain - - - - - - - - - - - - DUF1611 DYD1_k127_540516_6 483219.LILAB_33480 1.038e-54 207.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh DYD1_k127_540516_3 1121920.AUAU01000010_gene42 6.826e-78 283.0 COG4992@1|root,COG4992@2|Bacteria,3Y36P@57723|Acidobacteria 57723|Acidobacteria E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_540516_4 518766.Rmar_0946 7.188e-69 246.0 COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1FJUC@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Belongs to the ATCase OTCase family argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 ko:K09065,ko:K13043 ko00220,ko01100,ko01230,map00220,map01100,map01230 M00845 R07245,R08937 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD1_k127_540516_9 1115803.HMPREF1129_1643 5.144e-11 68.0 COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4D3QZ@85005|Actinomycetales 201174|Actinobacteria E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD1_k127_5408490_1 1123257.AUFV01000003_gene1057 5.576e-18 85.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1X61Y@135614|Xanthomonadales 135614|Xanthomonadales NU pilus assembly protein pilp pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP DYD1_k127_5408490_0 519989.ECTPHS_06482 1.709e-135 451.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales 135613|Chromatiales U type IV pilus secretin PilQ - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N DYD1_k127_5409561_2 1123368.AUIS01000019_gene1201 3.449e-89 300.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,2NCG9@225057|Acidithiobacillales 225057|Acidithiobacillales O DnaJ C terminal domain - - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C DYD1_k127_5409561_1 745310.G432_15595 1.252e-96 337.0 COG3182@1|root,COG3182@2|Bacteria,1MUX8@1224|Proteobacteria,2TVQ6@28211|Alphaproteobacteria,2K22D@204457|Sphingomonadales 204457|Sphingomonadales S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM DYD1_k127_5409561_0 1163407.UU7_00440 1.488e-145 486.0 COG4206@1|root,COG4206@2|Bacteria,1PGAD@1224|Proteobacteria,1S1QK@1236|Gammaproteobacteria,1X9HT@135614|Xanthomonadales 135614|Xanthomonadales H TonB-dependent Receptor Plug Domain - - - - - - - - - - - - Plug DYD1_k127_5409561_3 1134474.O59_002380 8.622e-63 234.0 COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria 1236|Gammaproteobacteria D cellulase activity - - - - - - - - - - - - - DYD1_k127_5409561_4 1134474.O59_002379 0.0001104 48.0 COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S7A2@1236|Gammaproteobacteria 1236|Gammaproteobacteria D sister chromatid segregation - - - - - - - - - - - - - DYD1_k127_5424624_2 1500890.JQNL01000001_gene3225 2.552e-41 161.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1X3SR@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_5424624_0 767434.Fraau_1736 9.341e-148 481.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1X4GX@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh DYD1_k127_5424624_1 155515.JP36_06145 5.124e-93 316.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1Y6ZD@135625|Pasteurellales 135625|Pasteurellales F ATP phosphoribosyltransferase hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C DYD1_k127_5424624_3 1384054.N790_03540 6.991e-28 115.0 COG4496@1|root,COG4496@2|Bacteria,1NAAX@1224|Proteobacteria,1SG3S@1236|Gammaproteobacteria,1X7DY@135614|Xanthomonadales 135614|Xanthomonadales S protein, YerC YecD - - - - - - - - - - - - Trp_repressor DYD1_k127_5450755_0 1207063.P24_16477 2.844e-210 659.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSG6@28211|Alphaproteobacteria,2JQUU@204441|Rhodospirillales 204441|Rhodospirillales C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 DYD1_k127_5450755_1 1082933.MEA186_21661 3.514e-43 166.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2TRA7@28211|Alphaproteobacteria,43GYD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C FAD linked glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 DYD1_k127_5461677_1 187272.Mlg_0001 1.056e-176 561.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales 135613|Chromatiales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N DYD1_k127_5461677_2 935863.AWZR01000001_gene1566 1.203e-120 397.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1X3F0@135614|Xanthomonadales 135614|Xanthomonadales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 DYD1_k127_5461677_3 1304275.C41B8_10415 6.86e-67 241.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N DYD1_k127_5461677_0 713586.KB900536_gene2143 2.972e-180 569.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales 135613|Chromatiales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD1_k127_5462731_1 1121878.AUGL01000005_gene2689 1.285e-89 301.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran DYD1_k127_5462731_0 330214.NIDE0029 1.893e-106 359.0 COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria 2|Bacteria KT transcription factor binding fhlA GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009 ko02020,ko02025,ko05132,map02020,map02025,map05132 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat DYD1_k127_5472048_0 519989.ECTPHS_05145 4.649e-130 426.0 COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria 1224|Proteobacteria M membrane - - - - - - - - - - - - DUF2339 DYD1_k127_5472048_4 1122134.KB893651_gene1908 6.841e-32 128.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria,1XKBY@135619|Oceanospirillales 135619|Oceanospirillales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD1_k127_5472048_7 1229276.DI53_0394 9.39e-23 106.0 28PD0@1|root,2ZC53@2|Bacteria,4NM6X@976|Bacteroidetes,1IRX2@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_5472048_9 1515746.HR45_07780 7.689e-06 58.0 COG5339@1|root,COG5339@2|Bacteria,1RI7E@1224|Proteobacteria,1S7H9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 DYD1_k127_5472048_2 502025.Hoch_5808 3.172e-63 229.0 COG2334@1|root,COG2334@2|Bacteria,1Q18Y@1224|Proteobacteria,42PIW@68525|delta/epsilon subdivisions,2WK5A@28221|Deltaproteobacteria,2YWIH@29|Myxococcales 28221|Deltaproteobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH DYD1_k127_5472048_5 313628.LNTAR_01402 8.313e-31 137.0 COG0373@1|root,COG0373@2|Bacteria 2|Bacteria H glutamyl-tRNA reductase activity hemA GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 ko:K02407,ko:K02492 ko00860,ko01100,ko01110,ko01120,ko02040,map00860,map01100,map01110,map01120,map02040 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000,ko02035 - - - GlutR_N,GlutR_dimer,Shikimate_DH DYD1_k127_5472048_3 604331.AUHY01000020_gene1913 6.688e-59 219.0 COG0181@1|root,COG0181@2|Bacteria,1WM2C@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC DYD1_k127_5472048_6 357808.RoseRS_1751 7.231e-24 111.0 COG1587@1|root,COG1587@2|Bacteria,2G70F@200795|Chloroflexi,375S5@32061|Chloroflexia 32061|Chloroflexia H PFAM Uroporphyrinogen III synthase HEM4 - - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 DYD1_k127_5472048_1 1121920.AUAU01000004_gene699 7.72e-85 291.0 COG0113@1|root,COG0113@2|Bacteria,3Y2VK@57723|Acidobacteria 57723|Acidobacteria H PFAM delta-aminolevulinic acid dehydratase - - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD DYD1_k127_5483680_5 42565.FP66_13425 1.426e-52 188.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1XHP7@135619|Oceanospirillales 135619|Oceanospirillales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 DYD1_k127_5483680_1 396588.Tgr7_1003 8.648e-294 924.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales 135613|Chromatiales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc DYD1_k127_5483680_9 305700.B447_03753 5.347e-20 96.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,2KWPI@206389|Rhodocyclales 206389|Rhodocyclales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA DYD1_k127_5483680_2 187272.Mlg_1946 1.318e-87 298.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales 135613|Chromatiales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N DYD1_k127_5483680_8 1479235.KK366039_gene2627 1.144e-32 129.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1XKH9@135619|Oceanospirillales 135619|Oceanospirillales J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 DYD1_k127_5483680_0 1279019.ARQK01000036_gene1618 4.171e-317 983.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales 135613|Chromatiales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 DYD1_k127_5483680_3 396588.Tgr7_1031 1.631e-79 274.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1WXFV@135613|Chromatiales 135613|Chromatiales J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c DYD1_k127_5483680_6 1122951.ATUE01000005_gene2241 7.967e-47 183.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,3NJPW@468|Moraxellaceae 1236|Gammaproteobacteria T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR DYD1_k127_5483680_4 713586.KB900536_gene591 6.108e-62 215.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1TJD2@1236|Gammaproteobacteria,1WYEP@135613|Chromatiales 135613|Chromatiales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF DYD1_k127_5483680_7 765914.ThisiDRAFT_2514 1.285e-41 154.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1WW7V@135613|Chromatiales 135613|Chromatiales D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge DYD1_k127_5506190_1 224911.27355948 8.779e-05 49.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,TPR_8 DYD1_k127_5506190_0 1298865.H978DRAFT_1162 1.19e-43 180.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,465TV@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_5529924_2 1234595.C725_0898 5.266e-44 165.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit MA20_01040 - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C DYD1_k127_5529924_1 1282876.BAOK01000002_gene891 7.509e-105 352.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,4BRV7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E PFAM Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 DYD1_k127_5529924_0 1177928.TH2_18471 3.493e-152 486.0 COG2807@1|root,COG2807@2|Bacteria,1QU0F@1224|Proteobacteria,2TTB4@28211|Alphaproteobacteria,2JPWW@204441|Rhodospirillales 204441|Rhodospirillales P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_5539800_1 1238182.C882_0684 7.36e-53 192.0 COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,2JRMS@204441|Rhodospirillales 204441|Rhodospirillales E L-seryl-tRNA selenium transferase selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA DYD1_k127_5539800_0 1123023.JIAI01000001_gene6772 8.481e-58 212.0 COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4DZ54@85010|Pseudonocardiales 201174|Actinobacteria O Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_5563148_2 765913.ThidrDRAFT_1708 7.341e-08 54.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1WYK3@135613|Chromatiales 135613|Chromatiales M Thiol disulfide interchange protein - - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA DYD1_k127_5563148_0 402881.Plav_0791 2.182e-79 278.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria,1JN9J@119043|Rhodobiaceae 28211|Alphaproteobacteria P Dimerisation domain of Zinc Transporter fieF - - ko:K13283 - - - - ko00000,ko02000 2.A.4.7.1 - - Cation_efflux,ZT_dimer DYD1_k127_5563148_1 78398.KS43_20285 1.251e-65 229.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1MQPR@122277|Pectobacterium 1236|Gammaproteobacteria E Cys/Met metabolism PLP-dependent enzyme ybdL GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008483,GO:0010326,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_5569671_1 1283300.ATXB01000001_gene1079 1.05e-82 278.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1XEW1@135618|Methylococcales 135618|Methylococcales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 DYD1_k127_5569671_0 1335757.SPICUR_01580 8.258e-92 309.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1WX49@135613|Chromatiales 135613|Chromatiales C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 DYD1_k127_5569671_2 204773.HEAR2920 6.309e-18 88.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,4736A@75682|Oxalobacteraceae 28216|Betaproteobacteria H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 DYD1_k127_558270_1 765914.ThisiDRAFT_1665 3.142e-91 303.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 DYD1_k127_558270_0 553385.JEMF01000006_gene3402 1.385e-145 468.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1XH9U@135619|Oceanospirillales 135619|Oceanospirillales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L DYD1_k127_558270_2 1027273.GZ77_18860 4.139e-51 183.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1XJJW@135619|Oceanospirillales 135619|Oceanospirillales J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 DYD1_k127_5585730_1 589873.EP13_13630 4.456e-65 239.0 2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,1T675@1236|Gammaproteobacteria,46DFK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5585730_0 566466.NOR53_3608 9.828e-100 333.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1RYC0@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD1_k127_5603920_2 234267.Acid_3123 1.728e-22 102.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD1_k127_5603920_0 1267535.KB906767_gene3664 1.049e-148 488.0 COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria 57723|Acidobacteria G PQQ-like domain - - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ_2 DYD1_k127_5603920_1 1163409.UUA_12545 2.224e-53 194.0 COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,1T04E@1236|Gammaproteobacteria,1XCYS@135614|Xanthomonadales 135614|Xanthomonadales S NAD(P)H-dependent FMN reductase - - - - - - - - - - - - FMN_red DYD1_k127_5603920_3 765913.ThidrDRAFT_2858 1.996e-08 60.0 COG0457@1|root,COG0457@2|Bacteria,1N3T7@1224|Proteobacteria,1SFI0@1236|Gammaproteobacteria,1WY1U@135613|Chromatiales 135613|Chromatiales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 DYD1_k127_56061_0 1211114.ALIP01000006_gene927 5.713e-139 451.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1X362@135614|Xanthomonadales 135614|Xanthomonadales G Dehydrogenase yliI - - - - - - - - - - - GSDH DYD1_k127_56061_3 187272.Mlg_1182 1.426e-49 182.0 COG0664@1|root,COG0664@2|Bacteria,1NI7I@1224|Proteobacteria,1SP73@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding DYD1_k127_56061_2 1007104.SUS17_2461 6.455e-93 318.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales 204457|Sphingomonadales G glucose sorbosone - - - - - - - - - - - - GSDH DYD1_k127_56061_1 1122919.KB905580_gene3157 3.317e-97 325.0 COG0526@1|root,COG0526@2|Bacteria,1TRBZ@1239|Firmicutes,4HDKP@91061|Bacilli,26SCQ@186822|Paenibacillaceae 91061|Bacilli CO Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotrans,Thioredoxin DYD1_k127_5608393_1 565045.NOR51B_409 1.647e-54 210.0 COG3258@1|root,COG4993@1|root,COG3258@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Dehydrogenase - - - - - - - - - - - - Cytochrome_CBB3,PQQ_2 DYD1_k127_5608393_0 1500897.JQNA01000002_gene2775 5.654e-99 326.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VJMJ@28216|Betaproteobacteria,1K058@119060|Burkholderiaceae 28216|Betaproteobacteria V Transport permease protein yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD1_k127_5617423_0 935863.AWZR01000007_gene217 3.358e-30 130.0 COG1595@1|root,COG1595@2|Bacteria,1QDHS@1224|Proteobacteria,1SS07@1236|Gammaproteobacteria,1X6DE@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_5626819_2 1121920.AUAU01000009_gene1856 9.999e-16 85.0 COG0406@1|root,COG0406@2|Bacteria,3Y906@57723|Acidobacteria 57723|Acidobacteria G Histidine phosphatase superfamily (branch 1) - - - - - - - - - - - - His_Phos_1 DYD1_k127_5626819_0 765912.Thimo_0453 9.682e-50 187.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1WY9X@135613|Chromatiales 135613|Chromatiales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 DYD1_k127_5626819_1 1075090.GOAMR_34_01130 3.577e-30 124.0 COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,4GE0Y@85026|Gordoniaceae 201174|Actinobacteria O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD1_k127_5631870_4 457415.HMPREF1006_01722 7.105e-05 46.0 COG1529@1|root,COG1529@2|Bacteria,3TAP1@508458|Synergistetes 508458|Synergistetes C Aldehyde oxidase and xanthine dehydrogenase - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_5631870_2 377629.TERTU_0906 3.624e-89 312.0 COG2885@1|root,COG2885@2|Bacteria,1P1AB@1224|Proteobacteria,1RMCQ@1236|Gammaproteobacteria,2PQ00@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M OmpA family oprF - - - - - - - - - - - OmpA DYD1_k127_5631870_0 1335757.SPICUR_01625 5.876e-143 461.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1WXEN@135613|Chromatiales 135613|Chromatiales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM DYD1_k127_5631870_1 765911.Thivi_1325 8.612e-105 349.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1WWN7@135613|Chromatiales 135613|Chromatiales OU PFAM peptidase - - - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N DYD1_k127_5631870_3 1121930.AQXG01000002_gene1988 1.541e-37 148.0 COG0739@1|root,COG0739@2|Bacteria,4NPNT@976|Bacteroidetes 976|Bacteroidetes M peptidase M23 - - - - - - - - - - - - Peptidase_M23 DYD1_k127_5637897_1 702113.PP1Y_AT11612 3.61e-60 215.0 COG1396@1|root,COG1396@2|Bacteria,1MUG2@1224|Proteobacteria,2TR3R@28211|Alphaproteobacteria,2K94Y@204457|Sphingomonadales 204457|Sphingomonadales K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31 DYD1_k127_5637897_0 886293.Sinac_5868 2.589e-101 342.0 COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes 203682|Planctomycetes G gluconolactonase - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD1_k127_5637897_3 234267.Acid_1337 1.446e-38 156.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - ko:K03088 - - - - ko00000,ko03021 - - - Glyoxalase DYD1_k127_5637897_2 402777.KB235903_gene1136 1.483e-44 172.0 COG0438@1|root,COG2242@1|root,COG2518@1|root,COG0438@2|Bacteria,COG2242@2|Bacteria,COG2518@2|Bacteria,1FZUY@1117|Cyanobacteria,1H72J@1150|Oscillatoriales 1117|Cyanobacteria M glycosyl transferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_11,Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_24 DYD1_k127_5643552_1 247633.GP2143_17801 2.891e-37 147.0 2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_5643552_0 247633.GP2143_17791 4.934e-81 278.0 28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5653424_0 566466.NOR53_1364 2.655e-143 464.0 COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1J6EW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P P COG0025 NhaP-type Na H and K H antiporters - - - ko:K11747 - - - - ko00000,ko02000 2.A.37.1.2 - - Na_H_Exchanger DYD1_k127_5653424_2 1123023.JIAI01000001_gene7783 1.303e-07 63.0 COG0346@1|root,COG0346@2|Bacteria,2HZ9F@201174|Actinobacteria,4E7GG@85010|Pseudonocardiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase,Glyoxalase_4 DYD1_k127_5653424_1 1123256.KB907928_gene1979 6.896e-16 78.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1X36N@135614|Xanthomonadales 135614|Xanthomonadales V Multidrug ABC transporter ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5664330_0 1185876.BN8_02239 6.874e-84 287.0 COG1520@1|root,COG2010@1|root,COG1520@2|Bacteria,COG2010@2|Bacteria,4NPS4@976|Bacteroidetes,47R6K@768503|Cytophagia 976|Bacteroidetes C PQQ-like domain - - 1.1.2.6 ko:K05889 - - R03136 - ko00000,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3 DYD1_k127_5664330_1 1118235.CAJH01000061_gene3430 3.43e-28 119.0 COG3453@1|root,COG3453@2|Bacteria,1N919@1224|Proteobacteria,1SEMT@1236|Gammaproteobacteria,1X8A2@135614|Xanthomonadales 135614|Xanthomonadales S Putative phosphatase (DUF442) - - - - - - - - - - - - DUF442 DYD1_k127_5687504_1 1161401.ASJA01000005_gene2506 4.738e-175 564.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2U0AK@28211|Alphaproteobacteria,43W7X@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD1_k127_5687504_0 314260.PB2503_11399 2.778e-276 864.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2U3RR@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 DYD1_k127_5687504_2 41431.PCC8801_4354 4.779e-88 301.0 COG1878@1|root,COG1878@2|Bacteria,1GG28@1117|Cyanobacteria 1117|Cyanobacteria S Putative cyclase - - - - - - - - - - - - Cyclase DYD1_k127_5687504_3 314230.DSM3645_20927 1.817e-37 154.0 COG2242@1|root,COG2242@2|Bacteria,2J0UY@203682|Planctomycetes 203682|Planctomycetes H TIGRFAM methyltransferase FkbM family - - - - - - - - - - - - Methyltransf_21 DYD1_k127_5687504_4 69279.BG36_13775 1.427e-33 140.0 COG2265@1|root,COG2265@2|Bacteria 2|Bacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rsmJ - 2.1.1.11,2.1.1.242 ko:K03428,ko:K07003,ko:K15984 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R04237 RC00003,RC00460 ko00000,ko00001,ko01000,ko03009 - - - Methyltransf_21,Methyltransf_25,Methyltransf_31,rRNA_methylase DYD1_k127_5687504_5 326298.Suden_0588 2.943e-05 54.0 COG0438@1|root,COG0438@2|Bacteria,1PEAX@1224|Proteobacteria,42SH3@68525|delta/epsilon subdivisions,2YR2F@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria H Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_5688665_5 886293.Sinac_5736 2.995e-13 73.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXGT@203682|Planctomycetes 203682|Planctomycetes C heme-binding domain, Pirellula Verrucomicrobium type - - - - - - - - - - - - Cytochrom_C DYD1_k127_5688665_6 1088721.NSU_2830 3.972e-08 60.0 2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_5688665_2 1298867.AUES01000015_gene3847 1.101e-49 186.0 COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2TSTP@28211|Alphaproteobacteria,3JU6V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short DYD1_k127_5688665_0 261292.Nit79A3_0148 2.156e-156 505.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2VJ9R@28216|Betaproteobacteria,372ES@32003|Nitrosomonadales 28216|Betaproteobacteria P TIGRFAM Sodium sulphate symporter - - - ko:K11106,ko:K14445 - - - - ko00000,ko02000 2.A.47.1,2.A.47.3.3 - - Na_sulph_symp DYD1_k127_5688665_4 1267534.KB906754_gene3222 5.503e-15 88.0 2F1DC@1|root,33UE4@2|Bacteria,3Y7M2@57723|Acidobacteria,2JMR0@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - DYD1_k127_5688665_1 1267534.KB906754_gene3223 3.986e-81 286.0 COG1131@1|root,COG1131@2|Bacteria,3Y6H3@57723|Acidobacteria,2JM7H@204432|Acidobacteriia 204432|Acidobacteriia V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran DYD1_k127_5688665_3 1267534.KB906754_gene3224 8.111e-45 166.0 COG1725@1|root,COG1725@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR DYD1_k127_5690091_0 1121438.JNJA01000002_gene3395 4.717e-188 610.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MAGR@213115|Desulfovibrionales 28221|Deltaproteobacteria C xanthine dehydrogenase a b hammerhead - - 1.17.1.4 ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2 DYD1_k127_5690091_2 941449.dsx2_3134 1.405e-60 212.0 COG2080@1|root,COG2080@2|Bacteria,1N1KQ@1224|Proteobacteria,42UD3@68525|delta/epsilon subdivisions,2WPH9@28221|Deltaproteobacteria,2M9N0@213115|Desulfovibrionales 28221|Deltaproteobacteria C 2Fe-2S -binding - - - - - - - - - - - - Fer2,Fer2_2 DYD1_k127_5690091_1 644968.DFW101_0022 8.265e-63 219.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2M9BS@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM Molybdopterin dehydrogenase, FAD-binding - - 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_569729_0 1089439.KB902251_gene1565 3.788e-182 583.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales 72273|Thiotrichales K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 DYD1_k127_569729_1 745277.GRAQ_03839 2.482e-36 138.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,3FHEP@34037|Rahnella 1236|Gammaproteobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 DYD1_k127_5707313_5 521011.Mpal_2329 0.0001207 47.0 COG0053@1|root,arCOG01474@2157|Archaea,2XVEP@28890|Euryarchaeota,2N96U@224756|Methanomicrobia 224756|Methanomicrobia P Dimerisation domain of Zinc Transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer DYD1_k127_5707313_3 390989.JOEG01000028_gene5455 2.211e-19 94.0 COG3871@1|root,COG3871@2|Bacteria 2|Bacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx DYD1_k127_5707313_4 713586.KB900536_gene2139 7.18e-15 76.0 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 DYD1_k127_5707313_2 187272.Mlg_2883 6.366e-26 110.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria 1236|Gammaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P DYD1_k127_5707313_0 765910.MARPU_16735 2.935e-136 452.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales 135613|Chromatiales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas DYD1_k127_5707313_1 1209072.ALBT01000031_gene1854 5.716e-27 115.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1FG23@10|Cellvibrio 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N DYD1_k127_5712036_1 1500894.JQNN01000001_gene4213 3.606e-53 199.0 2CJVH@1|root,2Z82D@2|Bacteria,1MX2M@1224|Proteobacteria 1224|Proteobacteria - - MA20_19455 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - DYD1_k127_5712036_0 190650.CC_0838 8.371e-87 293.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TY37@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ABC transporter MA20_19450 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5712036_3 931627.MycrhDRAFT_6044 2.132e-12 74.0 COG4319@1|root,COG4319@2|Bacteria,2INEA@201174|Actinobacteria 201174|Actinobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 DYD1_k127_5712036_2 1089550.ATTH01000002_gene32 1.227e-31 131.0 COG0670@1|root,COG0670@2|Bacteria,4NFZ7@976|Bacteroidetes 976|Bacteroidetes S Belongs to the BI1 family - - - ko:K06890 - - - - ko00000 - - - Bax1-I DYD1_k127_5736957_1 1042377.AFPJ01000020_gene2059 3.562e-69 240.0 COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8 DYD1_k127_5736957_3 1282876.BAOK01000001_gene3323 4.023e-60 218.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria,4BSQC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2 DYD1_k127_5736957_2 1282876.BAOK01000001_gene3322 1.952e-60 223.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,4BS3U@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 DYD1_k127_5736957_0 1117647.M5M_16685 3.235e-148 474.0 COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria 1236|Gammaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - DYD1_k127_5737807_0 519989.ECTPHS_02996 2.14e-138 447.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales 135613|Chromatiales J TIGRFAM ribonuclease, Rne Rng family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD1_k127_5737807_1 1395571.TMS3_0119575 8.014e-06 57.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Membrane yhdP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - AsmA_2,DUF3971 DYD1_k127_5739697_3 886293.Sinac_1155 2.301e-78 280.0 COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes 203682|Planctomycetes S Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_4 DYD1_k127_5739697_1 118166.JH976537_gene2732 4.57e-103 343.0 28KEA@1|root,2ZA0J@2|Bacteria 2|Bacteria H Sulfotransferase - - 2.8.2.1 ko:K01014 ko05204,map05204 - R01242 RC00007,RC00128 ko00000,ko00001,ko01000 - - - Sulfotransfer_1 DYD1_k127_5739697_0 1282876.BAOK01000001_gene3321 2.509e-181 594.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 DYD1_k127_5739697_2 1207063.P24_03555 5.68e-101 346.0 COG2807@1|root,COG2807@2|Bacteria 2|Bacteria P transmembrane transport - - - - - - - - - - - - MFS_1 DYD1_k127_5739697_5 1517416.IDAT_08900 4.052e-27 115.0 COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria,2QG2S@267893|Idiomarinaceae 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD DYD1_k127_5739697_4 1214065.BAGV01000019_gene2577 1.284e-64 231.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,282QA@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria C Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - iAF1260.b1656,iAPECO1_1312.APECO1_736,iB21_1397.B21_01616,iBWG_1329.BWG_1471,iE2348C_1286.E2348C_1742,iEC042_1314.EC042_1825,iEC55989_1330.EC55989_1824,iECABU_c1320.ECABU_c19090,iECBD_1354.ECBD_1987,iECB_1328.ECB_01626,iECDH10B_1368.ECDH10B_1790,iECDH1ME8569_1439.ECDH1ME8569_1601,iECD_1391.ECD_01626,iECED1_1282.ECED1_1855,iECH74115_1262.ECH74115_2368,iECIAI1_1343.ECIAI1_1708,iECO103_1326.ECO103_1797,iECO111_1330.ECO111_2126,iECO26_1355.ECO26_2385,iECOK1_1307.ECOK1_1775,iECP_1309.ECP_1601,iECS88_1305.ECS88_1705,iECSE_1348.ECSE_1780,iECSP_1301.ECSP_2222,iECUMN_1333.ECUMN_1946,iECW_1372.ECW_m1823,iECs_1301.ECs2365,iEKO11_1354.EKO11_2118,iETEC_1333.ETEC_1691,iEcDH1_1363.EcDH1_1984,iEcE24377_1341.EcE24377A_1869,iEcHS_1320.EcHS_A1735,iEcSMS35_1347.EcSMS35_1542,iEcolC_1368.EcolC_1973,iG2583_1286.G2583_2051,iJO1366.b1656,iJR904.b1656,iLF82_1304.LF82_2148,iNRG857_1313.NRG857_08300,iSBO_1134.SBO_1475,iSDY_1059.SDY_1882,iSFV_1184.SFV_1678,iSF_1195.SF1684,iSFxv_1172.SFxv_1892,iSSON_1240.SSON_1500,iS_1188.S1816,iSbBS512_1146.SbBS512_E1853,iUMN146_1321.UM146_08870,iUMNK88_1353.UMNK88_2117,iUTI89_1310.UTI89_C1847,iWFL_1372.ECW_m1823,iY75_1357.Y75_RS08680,iZ_1308.Z2678,ic_1306.c2050 Sod_Fe_C,Sod_Fe_N DYD1_k127_5744902_2 269796.Rru_A3406 6.548e-23 99.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2TQSM@28211|Alphaproteobacteria,2JQF9@204441|Rhodospirillales 204441|Rhodospirillales S Serine hydrolase involved in the detoxification of formaldehyde - - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase DYD1_k127_5744902_0 1356852.N008_17670 1.843e-47 177.0 COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,47P7A@768503|Cytophagia 976|Bacteroidetes H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx DYD1_k127_5744902_1 1434325.AZQN01000010_gene3965 6.093e-28 121.0 COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes 976|Bacteroidetes M Tricorn protease homolog - - - - - - - - - - - - Amidohydro_1,PD40 DYD1_k127_5749845_0 204669.Acid345_3040 4.17e-117 391.0 COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia 204432|Acidobacteriia Q Amidohydrolase family - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 DYD1_k127_575407_4 768671.ThimaDRAFT_3776 2.164e-25 114.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1WYI3@135613|Chromatiales 135613|Chromatiales S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE DYD1_k127_575407_1 765912.Thimo_1694 1.313e-143 473.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1WW1V@135613|Chromatiales 135613|Chromatiales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD1_k127_575407_0 1500890.JQNL01000001_gene2876 1.539e-148 479.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1X3CD@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 DYD1_k127_575407_2 1260251.SPISAL_02680 4.52e-83 285.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1WW2E@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase DYD1_k127_575407_3 1415780.JPOG01000001_gene1836 1.024e-59 210.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1X3R8@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate - - - - - - - - - - - - Pantoate_transf DYD1_k127_5778584_0 519989.ECTPHS_09048 1.536e-121 407.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB DYD1_k127_5778584_1 1384054.N790_12830 5.019e-42 156.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1X6DN@135614|Xanthomonadales 135614|Xanthomonadales C Part of a membrane complex involved in electron transport ydgM - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 DYD1_k127_5785519_1 438753.AZC_3354 1.68e-117 385.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria 28211|Alphaproteobacteria K metal-dependent hydrolase of the TIM-barrel fold MA20_26630 - - - - - - - - - - - Amidohydro_2 DYD1_k127_5785519_0 1123355.JHYO01000031_gene1599 9.75e-151 482.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,36Z0T@31993|Methylocystaceae 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold MA20_07975 - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_5785519_2 1500890.JQNL01000001_gene1897 6.017e-40 156.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1X9I6@135614|Xanthomonadales 135614|Xanthomonadales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh DYD1_k127_5829247_0 661478.OP10G_0311 2.026e-88 303.0 COG2382@1|root,COG2382@2|Bacteria 2|Bacteria P enterobactin catabolic process - - - - - - - - - - - - Esterase DYD1_k127_5829247_1 702113.PP1Y_Mpl784 9.968e-35 135.0 COG4188@1|root,COG4188@2|Bacteria,1NAS2@1224|Proteobacteria,2UPBC@28211|Alphaproteobacteria,2K3SY@204457|Sphingomonadales 204457|Sphingomonadales S dienelactone hydrolase - - - - - - - - - - - - - DYD1_k127_5829536_2 502025.Hoch_5586 2.271e-26 111.0 COG1337@1|root,COG1337@2|Bacteria,1PA2U@1224|Proteobacteria,432C9@68525|delta/epsilon subdivisions,2WY68@28221|Deltaproteobacteria 28221|Deltaproteobacteria L TIGRFAM CRISPR-associated RAMP protein, SSO1426 family - - - - - - - - - - - - RAMPs DYD1_k127_5829536_3 502025.Hoch_5587 1.733e-08 61.0 COG1337@1|root,COG1337@2|Bacteria 2|Bacteria L defense response to virus - - - - - - - - - - - - RAMPs DYD1_k127_5829536_4 502025.Hoch_6591 5.135e-05 49.0 2E05E@1|root,32VTR@2|Bacteria,1N5CW@1224|Proteobacteria,431HU@68525|delta/epsilon subdivisions,2WWRZ@28221|Deltaproteobacteria,2YVXX@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5829536_0 296591.Bpro_5300 2.916e-126 415.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2VJSV@28216|Betaproteobacteria,4AAZZ@80864|Comamonadaceae 28216|Betaproteobacteria O PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.18.1.3 ko:K00529 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - AIF_C,Pyr_redox_2,Reductase_C DYD1_k127_5829536_1 396588.Tgr7_0696 2.154e-105 354.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1WWFZ@135613|Chromatiales 135613|Chromatiales H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase DYD1_k127_5829628_2 381666.H16_B0949 3.443e-142 465.0 COG3303@1|root,COG3303@2|Bacteria,1R5JF@1224|Proteobacteria 1224|Proteobacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Cytochrom_C552,Cytochrom_c3_2 DYD1_k127_5829628_1 381666.H16_B0948 5.821e-174 568.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2VIEA@28216|Betaproteobacteria,1KFF9@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nirB - 1.18.1.1,1.7.1.15 ko:K00362,ko:K05297 ko00071,ko00910,ko01120,map00071,map00910,map01120 M00530 R00787,R02000 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 DYD1_k127_5829628_3 551789.ATVJ01000001_gene2539 1.538e-108 364.0 2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,2U1FE@28211|Alphaproteobacteria,43WDC@69657|Hyphomonadaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Alginate_exp DYD1_k127_5829628_0 1244869.H261_07468 2.514e-253 791.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TUIC@28211|Alphaproteobacteria,2JQGG@204441|Rhodospirillales 204441|Rhodospirillales P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component - - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran DYD1_k127_5833455_1 1288826.MSNKSG1_01993 1.779e-26 120.0 COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,1RYKJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the peptidase M17 family - - 3.4.11.1,3.4.11.5 ko:K01255,ko:K01259 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00135,R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 DYD1_k127_5833455_0 396588.Tgr7_2456 2.623e-116 379.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales 135613|Chromatiales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD1_k127_584577_0 395964.KE386496_gene2191 2.45e-19 102.0 COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,2U3IN@28211|Alphaproteobacteria,3NCAY@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_5850801_2 926569.ANT_22890 1.52e-06 50.0 COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi 200795|Chloroflexi S PFAM single-stranded nucleic acid binding R3H domain protein - - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H DYD1_k127_5850801_1 1042377.AFPJ01000035_gene2638 2.482e-50 188.0 29B18@1|root,2ZY02@2|Bacteria,1REMG@1224|Proteobacteria,1S4B1@1236|Gammaproteobacteria,46AUF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5850801_0 472759.Nhal_2032 5.45e-83 284.0 COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales 135613|Chromatiales O PFAM ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA DYD1_k127_5854288_0 1123256.KB907927_gene1577 5.363e-247 775.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1X2YS@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - - - - - - - - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 DYD1_k127_5854288_1 314260.PB2503_04937 2.259e-110 359.0 COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria 28211|Alphaproteobacteria E peptidase S9A, prolyl oligopeptidase domain protein beta-propeller ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N DYD1_k127_5854967_0 1122604.JONR01000004_gene853 3.838e-73 267.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria,1XDC3@135614|Xanthomonadales 135614|Xanthomonadales S cAMP biosynthetic process - - - - - - - - - - - - - DYD1_k127_5864789_1 1415780.JPOG01000001_gene1787 5.456e-20 101.0 COG3756@1|root,COG3756@2|Bacteria,1N7G4@1224|Proteobacteria,1SEVU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF1376 DYD1_k127_5864789_0 640511.BC1002_7259 1.382e-39 153.0 COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,2VJP8@28216|Betaproteobacteria,1K05N@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM Gp37Gp68 family protein - - - - - - - - - - - - DUF5131 DYD1_k127_5873000_1 1042377.AFPJ01000023_gene657 5.462e-14 73.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SdrD_B DYD1_k127_5873000_0 1232410.KI421425_gene1552 2.281e-140 458.0 COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales 28221|Deltaproteobacteria M OmpA family - - - - - - - - - - - - OmpA DYD1_k127_5882255_1 1238182.C882_0898 3.443e-73 260.0 COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,2TRSC@28211|Alphaproteobacteria,2JRQT@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K18990 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30,8.A.1 - - HlyD_D23 DYD1_k127_5882255_0 395493.BegalDRAFT_2091 1.64e-266 843.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran DYD1_k127_5893380_0 1049564.TevJSym_ad01400 5.252e-267 835.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1J52I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD1_k127_5893380_1 765914.ThisiDRAFT_0482 5.413e-151 490.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales 135613|Chromatiales E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD1_k127_5893380_2 765912.Thimo_1301 4.686e-142 461.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1WWZH@135613|Chromatiales 135613|Chromatiales EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_5893380_4 1442599.JAAN01000024_gene1906 1.31e-131 429.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1X4R7@135614|Xanthomonadales 135614|Xanthomonadales E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT DYD1_k127_5893380_3 1123020.AUIE01000001_gene2367 4.181e-140 460.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1YD43@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH DYD1_k127_5893380_5 1415779.JOMH01000001_gene2067 2.248e-48 181.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1X4DF@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin DYD1_k127_589999_2 1120983.KB894574_gene926 1.096e-31 127.0 COG1638@1|root,COG1638@2|Bacteria,1MUJY@1224|Proteobacteria,2TQNU@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP DYD1_k127_589999_1 1120983.KB894574_gene927 1.019e-145 486.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TRM1@28211|Alphaproteobacteria,1JQMN@119043|Rhodobiaceae 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM,DctQ DYD1_k127_589999_3 502025.Hoch_5742 4.275e-29 121.0 COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,42VFF@68525|delta/epsilon subdivisions,2WR8E@28221|Deltaproteobacteria,2Z2T8@29|Myxococcales 28221|Deltaproteobacteria S Domain of unknown function (DUF4212) - - - - - - - - - - - - DUF4212 DYD1_k127_589999_0 502025.Hoch_5743 7.87e-273 855.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria,2YZK2@29|Myxococcales 28221|Deltaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF DYD1_k127_5906071_2 1123277.KB893182_gene4743 5.14e-55 214.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia 976|Bacteroidetes QU Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,PD40 DYD1_k127_5906071_3 1123261.AXDW01000010_gene445 1.069e-45 170.0 COG1876@1|root,COG1876@2|Bacteria,1N1CQ@1224|Proteobacteria,1SASN@1236|Gammaproteobacteria,1X577@135614|Xanthomonadales 135614|Xanthomonadales M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY DYD1_k127_5906071_1 497964.CfE428DRAFT_0993 1.177e-55 209.0 COG1247@1|root,COG1247@2|Bacteria,46T83@74201|Verrucomicrobia 74201|Verrucomicrobia M Acetyltransferase (GNAT) domain - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 DYD1_k127_5906071_0 1437882.AZRU01000001_gene2039 2.838e-104 354.0 COG0427@1|root,COG0427@2|Bacteria,1PJY0@1224|Proteobacteria,1RPS6@1236|Gammaproteobacteria,1YFC9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Acetyl-CoA hydrolase/transferase C-terminal domain - - - - - - - - - - - - AcetylCoA_hyd_C DYD1_k127_5919957_1 292415.Tbd_0829 2.062e-40 160.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2VIKH@28216|Betaproteobacteria 28216|Betaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS DYD1_k127_5919957_0 1120999.JONM01000001_gene1105 5.756e-144 466.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,2KPP6@206351|Neisseriales 28216|Betaproteobacteria L DNA polymerase - - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP DYD1_k127_592128_3 338969.Rfer_0071 5.018e-18 89.0 29F9U@1|root,3027G@2|Bacteria,1RFT2@1224|Proteobacteria,2VS6S@28216|Betaproteobacteria,4AE04@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_592128_0 1524467.IV04_23335 1.769e-148 483.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,3ZZUU@613|Serratia 1236|Gammaproteobacteria F DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes dbpA GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C DYD1_k127_592128_2 697282.Mettu_1630 4.437e-43 164.0 2CN2H@1|root,32SG5@2|Bacteria,1N4PY@1224|Proteobacteria,1SESE@1236|Gammaproteobacteria,1XGHH@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - DYD1_k127_592128_1 861299.J421_5928 1.439e-67 238.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator - - - - - - - - - - - - HTH_18 DYD1_k127_5922215_1 626887.J057_04721 1.85e-150 491.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,46544@72275|Alteromonadaceae 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge DYD1_k127_5922215_5 765912.Thimo_0759 1.219e-48 176.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1WY7E@135613|Chromatiales 135613|Chromatiales J PFAM Endoribonuclease L-PSP - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP DYD1_k127_5922215_0 519989.ECTPHS_04239 3.512e-243 770.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS DYD1_k127_5922215_6 187272.Mlg_2443 8.075e-25 106.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales 135613|Chromatiales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 DYD1_k127_5922215_3 1158760.AQXP01000044_gene187 7.583e-60 213.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1WY9P@135613|Chromatiales 135613|Chromatiales F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin DYD1_k127_5922215_2 1415780.JPOG01000001_gene2417 3.539e-70 254.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,1X4G5@135614|Xanthomonadales 135614|Xanthomonadales S stress-induced protein - - - - - - - - - - - - DUF1732,YicC_N DYD1_k127_5922215_4 1049564.TevJSym_as00350 1.302e-51 191.0 COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,1SZE9@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Serine/threonine phosphatases, family 2C, catalytic domain - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 DYD1_k127_5922215_8 178901.AmDm5_1013 7.079e-07 57.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,2JQ9X@204441|Rhodospirillales 204441|Rhodospirillales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C DYD1_k127_5922215_7 1449351.RISW2_14510 9.61e-14 71.0 COG0614@1|root,COG0614@2|Bacteria,1NVK4@1224|Proteobacteria,2TRJ0@28211|Alphaproteobacteria,4KK80@93682|Roseivivax 28211|Alphaproteobacteria P ABC transporter - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 DYD1_k127_5923496_2 497964.CfE428DRAFT_4478 1.431e-05 55.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,46UMD@74201|Verrucomicrobia 2|Bacteria O Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 DYD1_k127_5923496_1 1121033.AUCF01000001_gene2206 6.991e-101 335.0 COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2TWFW@28211|Alphaproteobacteria,2JQWG@204441|Rhodospirillales 204441|Rhodospirillales I hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_5923496_0 314285.KT71_02512 2.601e-106 359.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1J8R1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - ko:K21430 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,GSDH DYD1_k127_5923496_3 1198452.Jab_2c25020 0.000146 48.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Calx-beta,DUF4842,Glyco_hydro_26,Phytase-like,VCBS DYD1_k127_5937112_2 187272.Mlg_2392 3.767e-122 404.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WXA3@135613|Chromatiales 135613|Chromatiales U General secretion pathway protein F - - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF DYD1_k127_5937112_0 765914.ThisiDRAFT_1295 7.2e-195 620.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N DYD1_k127_5937112_1 1033802.SSPSH_003278 1.078e-123 418.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU General Secretion Pathway protein gspD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N DYD1_k127_5943345_0 1122185.N792_05765 3.015e-121 411.0 COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,1RQUG@1236|Gammaproteobacteria,1X59Q@135614|Xanthomonadales 135614|Xanthomonadales S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 DYD1_k127_5943345_2 1122185.N792_05770 6.889e-46 171.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1X6M0@135614|Xanthomonadales 135614|Xanthomonadales S LemA family - - - - - - - - - - - - LemA DYD1_k127_5943345_1 880073.Calab_3470 1.086e-69 243.0 COG0020@1|root,COG0020@2|Bacteria,2NP9M@2323|unclassified Bacteria 2|Bacteria I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 ko:K00806,ko:K12503 ko00900,ko01110,map00900,map01110 - R06447,R08528 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD1_k127_594643_3 498761.HM1_1919 9.026e-34 137.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia 186801|Clostridia E Belongs to the TrpC family trpC - 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS DYD1_k127_594643_4 471852.Tcur_0886 4.024e-33 137.0 COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4EJWB@85012|Streptosporangiales 201174|Actinobacteria E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI DYD1_k127_594643_0 1121472.AQWN01000003_gene1630 1.054e-139 458.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,2602X@186807|Peptococcaceae 186801|Clostridia E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_594643_1 1121445.ATUZ01000015_gene1751 4.36e-59 214.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,2M9V0@213115|Desulfovibrionales 28221|Deltaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA DYD1_k127_594643_6 1218084.BBJK01000102_gene6428 1.724e-20 94.0 2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,2VX2T@28216|Betaproteobacteria,1K8JC@119060|Burkholderiaceae 28216|Betaproteobacteria S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 DYD1_k127_594643_5 1238182.C882_2255 4.943e-33 143.0 COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,2VGN6@28211|Alphaproteobacteria,2JUV4@204441|Rhodospirillales 204441|Rhodospirillales S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos DYD1_k127_594643_2 1380394.JADL01000017_gene488 8.764e-38 145.0 COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2JPM6@204441|Rhodospirillales 204441|Rhodospirillales S nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - - - - - - - - - - MoCF_biosynth DYD1_k127_5967918_4 565045.NOR51B_2870 8.289e-42 154.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,1J772@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD1_k127_5967918_3 483219.LILAB_16320 7.715e-43 160.0 COG0251@1|root,COG0251@2|Bacteria,1RES6@1224|Proteobacteria,435VN@68525|delta/epsilon subdivisions,2X0B9@28221|Deltaproteobacteria,2Z1FV@29|Myxococcales 28221|Deltaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD1_k127_5967918_0 1499689.CCNN01000007_gene2233 1.079e-161 521.0 COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,36H5G@31979|Clostridiaceae 186801|Clostridia C Aldehyde dehydrogenase family sucD - 1.2.1.76,1.2.1.87 ko:K13922,ko:K18119 ko00640,ko00650,ko01100,ko01200,map00640,map00650,map01100,map01200 - R09097,R09280 RC00004,RC00184 ko00000,ko00001,ko01000 - - - Aldedh DYD1_k127_5967918_2 1313172.YM304_29650 1.299e-116 389.0 COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia 84992|Acidimicrobiia C e3 binding domain - - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_5967918_1 1120983.KB894571_gene2483 1.684e-156 499.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit - - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_5971758_2 1298880.AUEV01000024_gene5278 6.043e-30 127.0 COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria 201174|Actinobacteria M mandelate racemase muconate lactonizing - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD1_k127_5971758_1 485918.Cpin_3132 1.673e-81 291.0 COG3182@1|root,COG3182@2|Bacteria,4NIWJ@976|Bacteroidetes,1IS7U@117747|Sphingobacteriia 976|Bacteroidetes S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM DYD1_k127_5971758_0 1280954.HPO_07417 2.379e-129 436.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,43XR0@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG4206 Outer membrane cobalamin receptor protein - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec DYD1_k127_5977091_1 1121937.AUHJ01000003_gene3216 1.953e-25 112.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria,466AI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Signal transduction protein - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD DYD1_k127_5977091_2 639030.JHVA01000001_gene1884 1.678e-18 97.0 28MSC@1|root,2ZB0S@2|Bacteria,3Y8PH@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - DYD1_k127_5977091_0 1453501.JELR01000005_gene1677 8.036e-32 132.0 COG2010@1|root,COG2133@1|root,COG2730@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2730@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - CBM_2,Cytochrome_CBB3,GSDH,PSCyt3,PSD3,PSD4,PSD5,SGL DYD1_k127_5978366_2 197221.22295770 6.166e-11 65.0 COG0115@1|root,COG0115@2|Bacteria,1G8CI@1117|Cyanobacteria 1117|Cyanobacteria H PFAM aminotransferase, class IV - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD1_k127_5978366_0 1380394.JADL01000009_gene3191 4.922e-92 318.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,2JPXT@204441|Rhodospirillales 204441|Rhodospirillales M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N DYD1_k127_5978366_1 391625.PPSIR1_41814 6.236e-30 124.0 COG1109@1|root,COG1482@1|root,COG1109@2|Bacteria,COG1482@2|Bacteria 2|Bacteria G cell wall glycoprotein biosynthetic process manA GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,1.6.5.5,2.7.7.13,5.3.1.8,5.4.2.10,5.4.2.2,5.4.2.8 ko:K00344,ko:K01809,ko:K01840,ko:K03431,ko:K04035,ko:K15778,ko:K16881 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko00860,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map00860,map01100,map01110,map01120,map01130 M00114,M00362 R00885,R00959,R01057,R01818,R01819,R02060,R06265,R06266,R06267,R08639,R10068 RC00002,RC00376,RC00408,RC00741,RC01491,RC01492,RC03042 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_3178,iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801 Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PMI_typeI DYD1_k127_6004618_1 1161401.ASJA01000009_gene1791 6.922e-11 68.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - - - - - - - - - - Cytochrom_D1,DUF305,Lactonase DYD1_k127_6004618_0 394221.Mmar10_0513 7.109e-57 224.0 COG1629@1|root,COG4771@2|Bacteria,1R0WC@1224|Proteobacteria,2U1A6@28211|Alphaproteobacteria,43WF4@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - OMP_b-brl_3,Plug,TonB_dep_Rec DYD1_k127_6009089_2 301.JNHE01000006_gene1145 4.838e-57 203.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1YEE5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF4478) ygdH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464,GO:0047405 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox DYD1_k127_6009089_1 396588.Tgr7_0189 2.032e-74 258.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria 1236|Gammaproteobacteria D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA DYD1_k127_6009089_0 1137799.GZ78_08570 6.929e-240 756.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1XHR3@135619|Oceanospirillales 135619|Oceanospirillales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 DYD1_k127_6009089_3 1294143.H681_15610 8.27e-53 189.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR DYD1_k127_6009089_4 247634.GPB2148_70 1.107e-25 111.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1J702@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB DYD1_k127_6015399_1 1232683.ADIMK_4142 3.573e-46 168.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,1RQIK@1236|Gammaproteobacteria,46C5D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase mhpB - - - - - - - - - - - LigB DYD1_k127_6015399_2 1123228.AUIH01000001_gene1405 8.231e-40 156.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,1XM11@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 DYD1_k127_6015399_0 1250232.JQNJ01000001_gene2805 4.128e-112 373.0 COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1HZK3@117743|Flavobacteriia 2|Bacteria G PQQ enzyme repeat - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD1_k127_601771_9 479434.Sthe_2670 8.376e-37 147.0 COG0842@1|root,COG0842@2|Bacteria,2G6II@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD1_k127_601771_6 1472418.BBJC01000004_gene1788 3.008e-57 214.0 2CBAE@1|root,31814@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_601771_7 351016.RAZWK3B_14034 2.446e-39 154.0 COG3647@1|root,COG3647@2|Bacteria,1RGJN@1224|Proteobacteria,2U80P@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Membrane - - - - - - - - - - - - - DYD1_k127_601771_3 1382356.JQMP01000003_gene1695 3.124e-95 322.0 COG0657@1|root,COG0657@2|Bacteria,2GBCM@200795|Chloroflexi,27YSU@189775|Thermomicrobia 189775|Thermomicrobia I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3 DYD1_k127_601771_1 1123023.JIAI01000001_gene6612 1.202e-115 387.0 COG1960@1|root,COG1960@2|Bacteria,2IAYB@201174|Actinobacteria,4E0DQ@85010|Pseudonocardiales 201174|Actinobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_2,Acyl-CoA_dh_N DYD1_k127_601771_2 234267.Acid_5561 1.027e-114 397.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 DYD1_k127_601771_4 765911.Thivi_0375 5.867e-70 245.0 COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1WXKN@135613|Chromatiales 135613|Chromatiales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes fliA - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_601771_5 521719.ATXQ01000002_gene2479 1.444e-58 216.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1YETS@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Flagellar regulatory protein FleQ fleQ - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat DYD1_k127_601771_8 234267.Acid_2870 4.405e-38 151.0 COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria 57723|Acidobacteria K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg DYD1_k127_601771_0 1026882.MAMP_02431 1.936e-158 511.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462DX@72273|Thiotrichales 72273|Thiotrichales M PFAM Mechanosensitive ion channel - - - - - - - - - - - - MS_channel DYD1_k127_601771_10 414684.RC1_2620 9.645e-34 137.0 COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,2TU8G@28211|Alphaproteobacteria,2JTBJ@204441|Rhodospirillales 204441|Rhodospirillales O Pyroglutamyl peptidase - - 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 DYD1_k127_601771_11 1280948.HY36_11725 3.889e-19 88.0 KOG2391@1|root,3279X@2|Bacteria,1RHDJ@1224|Proteobacteria,2U9SJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria O protein transport - - - - - - - - - - - - - DYD1_k127_6029382_2 713587.THITH_12630 3.037e-129 427.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1WYMX@135613|Chromatiales 135613|Chromatiales M Lytic murein transglycosylase - - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - PG_binding_1,SLT_2 DYD1_k127_6029382_1 1122132.AQYH01000010_gene4126 1.873e-129 427.0 COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,2TTEB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Small-conductance mechanosensitive channel - - - ko:K16053 - - - - ko00000,ko02000 1.A.23.4.5 - - MS_channel DYD1_k127_6029382_3 713586.KB900536_gene232 8.484e-115 385.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1WXYV@135613|Chromatiales 135613|Chromatiales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT DYD1_k127_6029382_4 596153.Alide_2603 1.611e-54 198.0 COG0590@1|root,COG0596@1|root,COG0590@2|Bacteria,COG0596@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,4A9VR@80864|Comamonadaceae 28216|Betaproteobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33,3.8.1.5 ko:K01563,ko:K11991 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223 RC00477,RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000,ko03016 - - - Abhydrolase_1,MafB19-deam,TfoX_C DYD1_k127_6029382_0 1279019.ARQK01000046_gene638 2.85e-220 689.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1WVVJ@135613|Chromatiales 135613|Chromatiales F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase DYD1_k127_603397_2 316274.Haur_1491 8.518e-25 105.0 arCOG14808@1|root,308PC@2|Bacteria,2G92H@200795|Chloroflexi,377C6@32061|Chloroflexia 32061|Chloroflexia S Domain of unknown function (DUF4956) - - - - - - - - - - - - DUF4956 DYD1_k127_603397_1 1248916.ANFY01000011_gene1068 4.374e-31 129.0 COG1225@1|root,COG1225@2|Bacteria,1MZN4@1224|Proteobacteria,2UA7Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA DYD1_k127_603397_0 1007104.SUS17_2461 1.591e-104 350.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales 204457|Sphingomonadales G glucose sorbosone - - - - - - - - - - - - GSDH DYD1_k127_6044188_0 886293.Sinac_1153 1.595e-161 525.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom DYD1_k127_6044963_3 1031711.RSPO_c02207 1.408e-23 101.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1K11Z@119060|Burkholderiaceae 28216|Betaproteobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase DYD1_k127_6044963_1 713586.KB900536_gene2983 1.834e-69 243.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1WX0F@135613|Chromatiales 135613|Chromatiales S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 DYD1_k127_6044963_2 379731.PST_2952 7.022e-60 223.0 COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,1SYEH@1236|Gammaproteobacteria,1Z0RY@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria KLT COG0515 Serine threonine protein kinase - - 2.7.11.1 ko:K08884,ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - Pkinase DYD1_k127_6044963_0 1283300.ATXB01000001_gene1631 8.514e-98 327.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XETA@135618|Methylococcales 135618|Methylococcales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran DYD1_k127_6048639_1 1265505.ATUG01000001_gene3101 8.081e-101 336.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2MJ8E@213118|Desulfobacterales 28221|Deltaproteobacteria P Domain of unknown function (DUF3333) pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 DYD1_k127_6048639_0 1049564.TevJSym_ax00050 1.215e-171 550.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1J4JR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3708 DYD1_k127_6048639_2 1117647.M5M_12620 1.521e-90 302.0 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,1J5D1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0226 ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 DYD1_k127_6061127_0 526225.Gobs_4161 7.487e-46 180.0 COG3243@1|root,COG3243@2|Bacteria,2GM1C@201174|Actinobacteria,4EU8A@85013|Frankiales 201174|Actinobacteria I alpha/beta hydrolase fold - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD1_k127_6061127_2 1345697.M493_14890 1.077e-05 50.0 COG2267@1|root,COG2267@2|Bacteria,1W2QR@1239|Firmicutes,4I0G2@91061|Bacilli,1WEWU@129337|Geobacillus 91061|Bacilli I Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH - 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_6063844_1 1123256.KB907926_gene915 1.566e-80 283.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1X2ZV@135614|Xanthomonadales 135614|Xanthomonadales M Lipoprotein releasing system transmembrane protein lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD DYD1_k127_6063844_0 1260251.SPISAL_04165 1.394e-86 301.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales 135613|Chromatiales M lipoprotein releasing system, transmembrane protein, LolC E family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD DYD1_k127_6113725_5 1415754.JQMK01000013_gene203 2.57e-34 135.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,464IR@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 DFP,Flavoprotein DYD1_k127_6113725_4 1122603.ATVI01000006_gene121 2.15e-66 235.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,1X61M@135614|Xanthomonadales 135614|Xanthomonadales F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase DYD1_k127_6113725_6 1122604.JONR01000007_gene2838 8.917e-12 74.0 2DJFD@1|root,305YN@2|Bacteria,1RJVQ@1224|Proteobacteria,1SIB3@1236|Gammaproteobacteria,1XDEZ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD1_k127_6113725_2 1187848.AJYQ01000004_gene134 3.263e-72 250.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,1XT4F@135623|Vibrionales 135623|Vibrionales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE GO:0003674,GO:0003824,GO:0004588,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran DYD1_k127_6113725_1 391615.ABSJ01000038_gene400 1.303e-107 356.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1J51Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L exodeoxyribonuclease III crc - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos DYD1_k127_6113725_0 450851.PHZ_c3485 6.653e-147 479.0 COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2TWGV@28211|Alphaproteobacteria,2KEXE@204458|Caulobacterales 204458|Caulobacterales G Major facilitator superfamily - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 DYD1_k127_6113725_3 349124.Hhal_2398 1.211e-66 233.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1WY2P@135613|Chromatiales 135613|Chromatiales J catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 DYD1_k127_6117588_4 1123236.KB899379_gene1331 5.12e-11 65.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,466PY@72275|Alteromonadaceae 1236|Gammaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm DYD1_k127_6117588_3 1122185.N792_04815 2.959e-12 75.0 COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,1X76E@135614|Xanthomonadales 135614|Xanthomonadales NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 DYD1_k127_6117588_1 323261.Noc_2460 6.648e-79 271.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1WXAU@135613|Chromatiales 135613|Chromatiales U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 DYD1_k127_6117588_0 1123399.AQVE01000005_gene892 8.677e-278 864.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,45ZWP@72273|Thiotrichales 72273|Thiotrichales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C DYD1_k127_6117588_2 1169143.KB911041_gene455 1.293e-13 75.0 COG0695@1|root,COG0695@2|Bacteria,1N82H@1224|Proteobacteria,2VWG7@28216|Betaproteobacteria,1K9F5@119060|Burkholderiaceae 28216|Betaproteobacteria O PFAM glutaredoxin 2 - - - - - - - - - - - - DUF836 DYD1_k127_6136392_0 1523503.JPMY01000002_gene3940 4.403e-115 391.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9 DYD1_k127_6136392_1 886293.Sinac_1155 6.842e-33 137.0 COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes 203682|Planctomycetes S Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_4 DYD1_k127_6176195_0 1121374.KB891576_gene233 3.27e-86 295.0 COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG3119 Arylsulfatase A and related enzymes atsA - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase DYD1_k127_6176195_1 1123054.KB907722_gene2930 7.127e-65 243.0 2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,1RRIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6176195_2 1161401.ASJA01000008_gene1624 2.003e-10 72.0 COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,2U0CF@28211|Alphaproteobacteria,43YJ9@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3 DYD1_k127_6178362_2 519989.ECTPHS_06762 2.001e-93 342.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1WWU1@135613|Chromatiales 135613|Chromatiales S TamB, inner membrane protein subunit of TAM complex - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB DYD1_k127_6178362_0 1121374.KB891586_gene2742 7.782e-219 682.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RRS7@1236|Gammaproteobacteria 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - RimK,TrkA_C DYD1_k127_6178362_1 331869.BAL199_17968 2.265e-125 410.0 COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,2TS8X@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the glutaminase family glsA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase DYD1_k127_6178362_3 1387312.BAUS01000004_gene1674 9.707e-91 303.0 COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,2KKJ6@206350|Nitrosomonadales 206350|Nitrosomonadales E Putative amidoligase enzyme (DUF2126) - - - - - - - - - - - - Bact_transglu_N,DUF2126,Transglut_core DYD1_k127_6191581_3 1082931.KKY_201 8.903e-41 158.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Dehydrogenase - - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 DYD1_k127_6191581_2 269797.Mbar_A1295 1.871e-54 199.0 COG0299@1|root,arCOG02825@2157|Archaea,2Y838@28890|Euryarchaeota,2N9JE@224756|Methanomicrobia 28890|Euryarchaeota F PFAM formyl transferase domain protein - - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N DYD1_k127_6191581_4 1449350.OCH239_18445 7.112e-31 133.0 COG2040@1|root,COG2040@2|Bacteria,1QU2A@1224|Proteobacteria,2TS3P@28211|Alphaproteobacteria,4KNKE@93682|Roseivivax 28211|Alphaproteobacteria E Homocysteine S-methyltransferase mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans DYD1_k127_6191581_1 1120983.KB894571_gene2692 1.076e-68 241.0 COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,2TWZ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Ion channel - - - - - - - - - - - - Ion_trans_2 DYD1_k127_6191581_0 400668.Mmwyl1_2755 1.396e-134 443.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XIU0@135619|Oceanospirillales 135619|Oceanospirillales C FAD linked oxidase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 DYD1_k127_6197039_1 713586.KB900536_gene1089 5.27e-42 160.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1WW30@135613|Chromatiales 135613|Chromatiales S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase DYD1_k127_6197039_0 1500893.JQNB01000001_gene1800 1.628e-97 349.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1X37J@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - AsmA_2,DUF3971 DYD1_k127_6200486_4 1532558.JL39_01675 2.962e-07 58.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,4BA0J@82115|Rhizobiaceae 28211|Alphaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 DYD1_k127_6200486_3 1217718.ALOU01000007_gene1258 4.986e-42 165.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2W0N2@28216|Betaproteobacteria 28216|Betaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 DYD1_k127_6200486_0 570952.ATVH01000018_gene3330 2.819e-101 345.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2JQVG@204441|Rhodospirillales 204441|Rhodospirillales O Belongs to the peptidase S1C family - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD1_k127_6200486_1 395493.BegalDRAFT_2781 1.758e-99 330.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria,460MF@72273|Thiotrichales 72273|Thiotrichales T Transcriptional regulatory protein, C terminal - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_6200486_2 1121935.AQXX01000106_gene574 4.509e-57 209.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1MW8M@1224|Proteobacteria,1RQPH@1236|Gammaproteobacteria,1XKDX@135619|Oceanospirillales 135619|Oceanospirillales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HATPase_c,HisKA DYD1_k127_6226225_1 228410.NE0015 1.045e-33 135.0 COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,2VHVP@28216|Betaproteobacteria,372TW@32003|Nitrosomonadales 28216|Betaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain yfhK - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_6226225_0 426114.THI_0055 7.044e-162 523.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KK5X@119065|unclassified Burkholderiales 28216|Betaproteobacteria T Response regulator receiver yfhA - - ko:K07714,ko:K07715 ko02020,ko02024,map02020,map02024 M00500,M00502 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_6226225_3 686578.AFFX01000002_gene614 4.822e-13 74.0 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1S52P@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Outer Membrane Lipoprotein ycfJ - - - - - - - - - - - Rick_17kDa_Anti DYD1_k127_6226225_2 1395571.TMS3_0102290 2.813e-33 139.0 COG2823@1|root,COG2823@2|Bacteria,1RHX0@1224|Proteobacteria,1S742@1236|Gammaproteobacteria 1236|Gammaproteobacteria S bacterial OsmY and nodulation domain - - - - - - - - - - - - BON DYD1_k127_6230153_4 562970.Btus_1721 6.414e-30 125.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,2781D@186823|Alicyclobacillaceae 91061|Bacilli E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 DYD1_k127_6230153_3 1163617.SCD_n02532 4.843e-69 247.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria 28216|Betaproteobacteria EH Glutamine amidotransferase of anthranilate synthase trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase DYD1_k127_6230153_2 292459.STH1407 1.133e-123 412.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia 186801|Clostridia EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind DYD1_k127_6230153_1 523791.Kkor_0209 2.702e-185 597.0 COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD1_k127_6230153_0 1232410.KI421415_gene3088 1.847e-233 737.0 COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,42PQK@68525|delta/epsilon subdivisions,2WJCT@28221|Deltaproteobacteria,43T12@69541|Desulfuromonadales 28221|Deltaproteobacteria V ABC transporter - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_6230153_5 863365.XHC_1251 1.452e-27 119.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales 135614|Xanthomonadales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase DYD1_k127_6230669_6 1123228.AUIH01000001_gene1243 2.71e-25 106.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1XHWW@135619|Oceanospirillales 135619|Oceanospirillales S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin DYD1_k127_6230669_5 234267.Acid_5494 7.094e-64 231.0 COG3622@1|root,COG3622@2|Bacteria,3Y6XP@57723|Acidobacteria 57723|Acidobacteria G Xylose isomerase-like TIM barrel - - 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 DYD1_k127_6230669_2 285535.JOEY01000011_gene6150 1.173e-71 249.0 COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria 201174|Actinobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short,adh_short_C2 DYD1_k127_6230669_3 66874.JOFS01000008_gene2290 7.747e-71 251.0 COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria 201174|Actinobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_6230669_4 314264.ROS217_12636 7.125e-67 236.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria,46R3G@74030|Roseovarius 28211|Alphaproteobacteria P COG0725 ABC-type molybdate transport system, periplasmic component modA GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 DYD1_k127_6230669_0 1379270.AUXF01000001_gene2129 2.991e-114 381.0 COG1304@1|root,COG1304@2|Bacteria,1ZUNQ@142182|Gemmatimonadetes 2|Bacteria C FMN-dependent dehydrogenase - - 1.1.3.15,1.1.3.46 ko:K00104,ko:K16422 ko00261,ko00630,ko01055,ko01100,ko01110,ko01120,ko01130,map00261,map00630,map01055,map01100,map01110,map01120,map01130 - R00475,R06633 RC00042,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh DYD1_k127_6230669_7 1007104.SUS17_2414 9.081e-12 72.0 2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_6230669_1 582402.Hbal_0890 3.443e-102 341.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2U0AK@28211|Alphaproteobacteria,43W7X@69657|Hyphomonadaceae 28211|Alphaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD1_k127_6231497_0 1121931.AUHG01000019_gene3055 4.094e-84 284.0 COG0702@1|root,COG0702@2|Bacteria,4NICI@976|Bacteroidetes,1IIU7@117743|Flavobacteriia 976|Bacteroidetes GM NmrA-like family - - - - - - - - - - - - NmrA DYD1_k127_6231497_1 383372.Rcas_2758 4.271e-32 138.0 COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,377RE@32061|Chloroflexia 32061|Chloroflexia H PFAM Methionine synthase, vitamin-B12 independent - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_6233968_1 234267.Acid_1969 6.141e-67 232.0 COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria 2|Bacteria Q PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_1 DYD1_k127_6233968_0 1379698.RBG1_1C00001G1351 3.606e-146 471.0 COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria 2|Bacteria E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_6235355_0 1088721.NSU_2821 1.312e-210 675.0 COG4206@1|root,COG4206@2|Bacteria,1N71E@1224|Proteobacteria,2TU7B@28211|Alphaproteobacteria,2K23K@204457|Sphingomonadales 204457|Sphingomonadales H TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_6235355_1 627192.SLG_09880 1.924e-08 64.0 28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_6243448_0 666681.M301_0049 2.597e-91 331.0 COG0457@1|root,COG0457@2|Bacteria,1RA3P@1224|Proteobacteria,2VRWC@28216|Betaproteobacteria,2KNR7@206350|Nitrosomonadales 28216|Betaproteobacteria S Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA pgaA - - ko:K11935 ko02026,map02026 - - - ko00000,ko00001 - - - TPR_15,TPR_16,TPR_19 DYD1_k127_6243448_1 1040987.AZUY01000001_gene2594 1.466e-87 299.0 COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TUAM@28211|Alphaproteobacteria,43PW5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD1_k127_6243448_2 1120972.AUMH01000006_gene1809 4.339e-36 151.0 COG0657@1|root,COG0657@2|Bacteria,1UWRG@1239|Firmicutes,4I9QW@91061|Bacilli,27AB6@186823|Alicyclobacillaceae 91061|Bacilli I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3 DYD1_k127_6252634_0 97096.XP_007790920.1 6.113e-127 426.0 COG1574@1|root,2RS8Z@2759|Eukaryota,3918Y@33154|Opisthokonta,3PXJ9@4751|Fungi,3RGKA@4890|Ascomycota,21EIX@147550|Sordariomycetes 4751|Fungi S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD1_k127_6256967_2 1286106.MPL1_10883 6.031e-120 391.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,45ZT3@72273|Thiotrichales 72273|Thiotrichales P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N DYD1_k127_6256967_0 1260251.SPISAL_05890 1.68e-142 468.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1WWTY@135613|Chromatiales 135613|Chromatiales FP Belongs to the GppA Ppx family - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA DYD1_k127_6256967_5 697282.Mettu_3560 9.225e-50 183.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1XF7Y@135618|Methylococcales 135618|Methylococcales C Iron-sulfur cluster insertion protein ErpA erpA - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn DYD1_k127_6256967_6 395493.BegalDRAFT_1306 7.099e-33 132.0 COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,461BH@72273|Thiotrichales 72273|Thiotrichales M Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin DYD1_k127_6256967_7 396588.Tgr7_2410 5.173e-16 90.0 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,1WZS1@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD1_k127_6256967_4 1304275.C41B8_14395 2.495e-54 196.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX DYD1_k127_6256967_1 502025.Hoch_6599 9.511e-125 410.0 COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales 28221|Deltaproteobacteria E Prephenate dehydrogenase chorismate mutase - - 1.3.1.12 ko:K00210 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - CM_2,PDH DYD1_k127_6256967_3 314278.NB231_06516 1.573e-73 252.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1WXDM@135613|Chromatiales 135613|Chromatiales S Serine hydrolase involved in the detoxification of formaldehyde - - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase DYD1_k127_6269067_0 1198232.CYCME_1232 4.78e-204 648.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,4602T@72273|Thiotrichales 72273|Thiotrichales C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,NAD_binding_8 DYD1_k127_6269067_1 644282.Deba_0465 2.567e-90 306.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,42P5R@68525|delta/epsilon subdivisions,2WJDU@28221|Deltaproteobacteria 28221|Deltaproteobacteria I TIGRFAM acetoacetyl-CoA synthase - - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD1_k127_6274819_2 627192.SLG_09870 4.745e-18 89.0 2C42J@1|root,3359Y@2|Bacteria,1NJYP@1224|Proteobacteria,2UJHF@28211|Alphaproteobacteria,2KE0P@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_6274819_1 1042377.AFPJ01000051_gene33 9.504e-84 287.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B DYD1_k127_6274819_0 1265313.HRUBRA_00697 1.3e-125 413.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RYET@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Zn-dependent dipeptidase, microsomal dipeptidase - - - - - - - - - - - - Peptidase_M19 DYD1_k127_6278097_1 1286106.MPL1_10677 7.207e-30 129.0 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,460N9@72273|Thiotrichales 72273|Thiotrichales NU TIGRFAM type IV pilus biogenesis stability protein PilW - - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_2,TPR_8 DYD1_k127_6278097_2 1123393.KB891328_gene634 2.249e-19 100.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,1KSP5@119069|Hydrogenophilales 119069|Hydrogenophilales S Helix-turn-helix domain - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 DYD1_k127_6278097_0 396588.Tgr7_2048 1.738e-118 387.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1WWGZ@135613|Chromatiales 135613|Chromatiales J PFAM tRNA synthetase class II (G H P and S) hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD1_k127_6295022_1 1121918.ARWE01000001_gene951 1.189e-25 113.0 COG4967@1|root,COG4967@2|Bacteria,1RKKA@1224|Proteobacteria,42Y2V@68525|delta/epsilon subdivisions,2WTFM@28221|Deltaproteobacteria,43V82@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Pfam:N_methyl_2 - - - ko:K10927 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl DYD1_k127_6295022_0 338963.Pcar_0394 2.578e-55 204.0 COG2165@1|root,COG2165@2|Bacteria,1RK34@1224|Proteobacteria,42Y1S@68525|delta/epsilon subdivisions,2WTH8@28221|Deltaproteobacteria,43U7J@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K12285 - - - - ko00000,ko02044 - - - N_methyl DYD1_k127_6295022_2 338963.Pcar_0395 5.391e-22 100.0 COG4726@1|root,COG4726@2|Bacteria,1PQMG@1224|Proteobacteria,430ZZ@68525|delta/epsilon subdivisions,2WWZF@28221|Deltaproteobacteria,43VI0@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Pilus assembly protein PilX - - - ko:K12286 - - - - ko00000,ko02044 - - - - DYD1_k127_6300930_1 314285.KT71_01820 1.056e-24 106.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,1J9HJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 DYD1_k127_6300930_0 566466.NOR53_398 1.175e-44 179.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,1J55S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PEGA DYD1_k127_6320014_2 227086.JGI_V11_67125 1.7e-65 229.0 COG1012@1|root,KOG2450@2759|Eukaryota 2759|Eukaryota C aldehyde dehydrogenase (NAD) activity - - - - - - - - - - - - Aldedh DYD1_k127_6320014_1 1121918.ARWE01000001_gene687 3.623e-71 247.0 COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria 1224|Proteobacteria S Haloacid dehalogenase, type II hadL - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 DYD1_k127_6320014_0 1121374.KB891585_gene2195 6.818e-149 479.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P protein conserved in bacteria - - 5.3.2.8 ko:K16514 ko00362,ko01120,map00362,map01120 - R07839 RC02426 ko00000,ko00001,ko01000 - - - PrpF DYD1_k127_6320014_3 269797.Mbar_A1661 3.352e-40 150.0 COG1228@1|root,arCOG00696@2157|Archaea,2XWAY@28890|Euryarchaeota 28890|Euryarchaeota Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 DYD1_k127_6334054_2 290398.Csal_1172 2.885e-72 252.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1XK9S@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA - 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 DYD1_k127_6334054_1 1089552.KI911559_gene2747 7.24e-80 281.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2TUFR@28211|Alphaproteobacteria,2JRU5@204441|Rhodospirillales 204441|Rhodospirillales S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase DYD1_k127_6334054_3 1168065.DOK_10677 2.42e-48 183.0 COG3907@1|root,COG3907@2|Bacteria,1MU4M@1224|Proteobacteria,1RQ2Y@1236|Gammaproteobacteria,1J7E2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG3907 PAP2 (acid phosphatase) superfamily protein - - - - - - - - - - - - PAP2 DYD1_k127_6334054_4 439235.Dalk_2737 3.314e-27 115.0 2E451@1|root,32Z13@2|Bacteria,1N0RY@1224|Proteobacteria,42UM1@68525|delta/epsilon subdivisions,2WQAD@28221|Deltaproteobacteria,2MM3Q@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6334054_0 1121448.DGI_0628 6.171e-92 311.0 COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,42PYV@68525|delta/epsilon subdivisions,2WK2G@28221|Deltaproteobacteria,2M9U8@213115|Desulfovibrionales 28221|Deltaproteobacteria P Domain of unknown function (DUF4198) - - - ko:K02009 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18 - - DUF4198 DYD1_k127_6334620_0 408672.NBCG_05438 4.498e-36 144.0 COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4DREM@85009|Propionibacteriales 201174|Actinobacteria GM NmrA-like family - - 1.6.5.2 ko:K19267 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - NAD_binding_10,NmrA DYD1_k127_6339694_2 565045.NOR51B_2202 1.489e-101 339.0 COG1988@1|root,COG1988@2|Bacteria,1PCAC@1224|Proteobacteria,1RYI5@1236|Gammaproteobacteria,1J4XB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S membrane-bound metal-dependent hydrolases - - - ko:K07038 - - - - ko00000 - - - YdjM DYD1_k127_6339694_1 1121948.AUAC01000008_gene821 1.17e-134 434.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,43WME@69657|Hyphomonadaceae 28211|Alphaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C DYD1_k127_6339694_0 1082931.KKY_2582 1.901e-195 626.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Dehydrogenase - - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 DYD1_k127_6339694_3 497964.CfE428DRAFT_3322 4.213e-63 230.0 COG0715@1|root,COG0715@2|Bacteria,46U6U@74201|Verrucomicrobia 74201|Verrucomicrobia P Protein of unknown function (DUF3500) - - - - - - - - - - - - DUF3500 DYD1_k127_6352969_5 472759.Nhal_0363 6.414e-76 263.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1X28I@135613|Chromatiales 135613|Chromatiales M Lysin motif - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD1_k127_6352969_6 761193.Runsl_2118 4.143e-43 162.0 COG3542@1|root,COG3542@2|Bacteria,4NPCH@976|Bacteroidetes,47PD8@768503|Cytophagia 976|Bacteroidetes S Cupin superfamily (DUF985) - - - ko:K09705 - - - - ko00000 - - - Cupin_5 DYD1_k127_6352969_7 745411.B3C1_04625 8.555e-31 136.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,1S3RZ@1236|Gammaproteobacteria,1J6M6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6352969_3 1379270.AUXF01000005_gene644 2.545e-78 269.0 28NKC@1|root,2ZBM7@2|Bacteria,1ZUHB@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - DYD1_k127_6352969_0 1088721.NSU_3380 3.725e-199 631.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales 204457|Sphingomonadales C belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_6352969_2 1121374.KB891586_gene2544 8.834e-79 264.0 2BDUH@1|root,302AN@2|Bacteria,1RF2Q@1224|Proteobacteria 1224|Proteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD1_k127_6352969_1 666685.R2APBS1_3710 4.1e-85 289.0 COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,1RZ5N@1236|Gammaproteobacteria,1X3AH@135614|Xanthomonadales 135614|Xanthomonadales M Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 DYD1_k127_6352969_4 1123504.JQKD01000012_gene1270 3.962e-77 262.0 COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,2VJ0Y@28216|Betaproteobacteria,4AE5W@80864|Comamonadaceae 28216|Betaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_6362501_0 1441930.Z042_09515 0.0 1260.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,401NJ@613|Serratia 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD1_k127_6370455_0 530564.Psta_2447 5.232e-104 353.0 COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes 203682|Planctomycetes H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase DYD1_k127_6370455_1 926550.CLDAP_19070 1.615e-65 235.0 COG3253@1|root,COG3253@2|Bacteria 2|Bacteria S peroxidase activity ywfI - - ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R11522 RC00884 ko00000,ko00001,ko01000 - - - Chlor_dismutase DYD1_k127_6370455_2 519442.Huta_2317 5.078e-16 79.0 COG0407@1|root,arCOG03323@2157|Archaea,2XV21@28890|Euryarchaeota,23TFQ@183963|Halobacteria 183963|Halobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D DYD1_k127_6379224_1 1448139.AI20_06510 3.934e-22 100.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1Y5Z6@135624|Aeromonadales 135624|Aeromonadales S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 DYD1_k127_6379224_0 1121937.AUHJ01000003_gene3229 1.177e-94 335.0 COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CBM9_1,HATPase_c,HisKA DYD1_k127_6381598_4 1260251.SPISAL_06505 7.662e-32 132.0 COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria,1WZ46@135613|Chromatiales 135613|Chromatiales S PFAM electron transport protein SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD1_k127_6381598_2 1479237.JMLY01000001_gene2472 4.306e-76 269.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,464PR@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS DYD1_k127_6381598_0 472759.Nhal_0274 2.251e-169 538.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1WXNW@135613|Chromatiales 135613|Chromatiales E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt DYD1_k127_6381598_1 565045.NOR51B_989 4.538e-148 476.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1J5B6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD1_k127_6381598_3 519989.ECTPHS_11115 2.886e-70 270.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1WVVA@135613|Chromatiales 135613|Chromatiales NU FimV C-terminal - - - ko:K08086 - - - - ko00000 - - - TPR_19 DYD1_k127_64094_2 1123508.JH636439_gene1806 5.847e-10 61.0 COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_64094_1 28377.ENSACAP00000011111 2.97e-32 144.0 COG0666@1|root,KOG4369@1|root,KOG0504@2759|Eukaryota,KOG4369@2759|Eukaryota,38I05@33154|Opisthokonta,3BHRH@33208|Metazoa,3CU4I@33213|Bilateria,47Z9E@7711|Chordata,490ZB@7742|Vertebrata 33208|Metazoa T ankyrin repeat ANKRD17 GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112 - ko:K16726 - - - - ko00000,ko03036 - - - Ank_2,Ank_4,KH_1 DYD1_k127_64094_0 234267.Acid_2073 3.414e-60 219.0 COG0296@1|root,COG2382@1|root,COG0296@2|Bacteria,COG2382@2|Bacteria,3Y6V1@57723|Acidobacteria 57723|Acidobacteria GP Belongs to the glycosyl hydrolase 13 family - - - ko:K07214 - - - - ko00000 - - - CBM_48,Esterase DYD1_k127_64094_4 493475.GARC_0304 3.87e-07 56.0 2EHHF@1|root,33B9C@2|Bacteria,1NM2H@1224|Proteobacteria,1SECY@1236|Gammaproteobacteria,46BWB@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_64094_3 58344.JOEL01000021_gene5071 1.749e-07 55.0 COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria 201174|Actinobacteria S protein conserved in bacteria - - - - - - - - - - - - Zincin_1 DYD1_k127_6417849_4 1179778.PMM47T1_02869 7.424e-07 56.0 COG1639@1|root,COG1639@2|Bacteria,1N7EN@1224|Proteobacteria,1RT8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Signal transduction protein - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - HDOD DYD1_k127_6417849_1 1437824.BN940_04631 2.94e-70 250.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,3T1WH@506|Alcaligenaceae 28216|Betaproteobacteria E Cys/Met metabolism PLP-dependent enzyme metC - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K01761 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP DYD1_k127_6417849_2 1385517.N800_07970 7.966e-64 231.0 COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1X6C4@135614|Xanthomonadales 135614|Xanthomonadales S MOSC N-terminal beta barrel domain - - - ko:K07140 - - - - ko00000 - - - MOSC,MOSC_N DYD1_k127_6417849_0 5691.EAN77147 1.138e-135 447.0 COG0626@1|root,KOG0053@2759|Eukaryota,3XT9E@5653|Kinetoplastida 5653|Kinetoplastida E cystathione gamma lyase - - - - - - - - - - - - Cys_Met_Meta_PP DYD1_k127_6417849_3 518766.Rmar_1576 1.093e-08 59.0 COG1514@1|root,COG1514@2|Bacteria,4NVAV@976|Bacteroidetes,1FJJK@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase DYD1_k127_6417953_2 314287.GB2207_11253 1.218e-27 119.0 COG3038@1|root,COG3038@2|Bacteria,1NFHR@1224|Proteobacteria 1224|Proteobacteria C Prokaryotic cytochrome b561 - - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB DYD1_k127_6417953_3 555793.WSK_4047 2.691e-16 89.0 28NHI@1|root,2ZBJA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6417953_0 1254432.SCE1572_08525 9.988e-150 489.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42MPR@68525|delta/epsilon subdivisions,2WNM3@28221|Deltaproteobacteria,2Z06N@29|Myxococcales 28221|Deltaproteobacteria Q Multicopper oxidase - - - ko:K04753 - - - - ko00000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD1_k127_6435961_2 1211115.ALIQ01000198_gene446 3.924e-116 377.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3NC6F@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.39 ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_6435961_3 1380391.JIAS01000001_gene2599 1.958e-56 199.0 COG0599@1|root,COG0599@2|Bacteria,1RDSG@1224|Proteobacteria,2U72V@28211|Alphaproteobacteria,2JZJM@204441|Rhodospirillales 204441|Rhodospirillales S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD1_k127_6435961_1 935840.JAEQ01000020_gene2320 5.729e-152 494.0 COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2U0KM@28211|Alphaproteobacteria,43M1M@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_6435961_0 1385511.N783_00010 1.881e-175 570.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli 91061|Bacilli CG PQQ enzyme repeat - - - - - - - - - - - - Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3 DYD1_k127_6439419_4 583355.Caka_0033 1.498e-19 100.0 COG3119@1|root,COG3119@2|Bacteria,46UWH@74201|Verrucomicrobia 74201|Verrucomicrobia P Sulfatase - - - - - - - - - - - - Sulfatase DYD1_k127_6439419_0 1121374.KB891575_gene1258 2.667e-205 647.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793 ELFV_dehydrog,ELFV_dehydrog_N DYD1_k127_6439419_1 1280948.HY36_13850 7.84e-155 499.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,43X36@69657|Hyphomonadaceae 28211|Alphaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - - - - - - - - - - SDF DYD1_k127_6439419_2 391625.PPSIR1_35862 1.36e-42 174.0 COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales 28221|Deltaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase DYD1_k127_6439419_3 1173028.ANKO01000126_gene4098 2.24e-20 100.0 COG0666@1|root,COG0666@2|Bacteria,1G5HC@1117|Cyanobacteria,1HG0J@1150|Oscillatoriales 1117|Cyanobacteria S Ankyrin repeat - - - - - - - - - - - - Ank_2 DYD1_k127_6443194_0 1192034.CAP_3222 5.262e-99 349.0 COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,42QGZ@68525|delta/epsilon subdivisions,2WKE6@28221|Deltaproteobacteria,2YYP7@29|Myxococcales 28221|Deltaproteobacteria M CotH kinase protein - - - - - - - - - - - - CotH DYD1_k127_6443194_1 1117647.M5M_01925 9.166e-06 53.0 2EC2G@1|root,3361J@2|Bacteria,1N9TS@1224|Proteobacteria,1SDE9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6445948_0 1049564.TevJSym_ab00650 6.296e-190 613.0 COG2304@1|root,COG2304@2|Bacteria,1MXU0@1224|Proteobacteria,1RZHF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S serine threonine protein kinase ppkA - 2.7.11.1 ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - VWA,VWA_2 DYD1_k127_6445948_5 1049564.TevJSym_ab00640 1.621e-63 226.0 COG1136@1|root,COG1136@2|Bacteria,1RCXK@1224|Proteobacteria,1S7TZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria V abc transporter atp-binding protein attE - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_6445948_2 1049564.TevJSym_ab00630 4.016e-106 357.0 COG0577@1|root,COG0577@2|Bacteria,1QRYR@1224|Proteobacteria,1S0ZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria V ABC-type antimicrobial peptide transport system, permease component tagS - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX DYD1_k127_6445948_3 1123073.KB899243_gene824 1.13e-80 287.0 COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,1RQRZ@1236|Gammaproteobacteria,1X4YB@135614|Xanthomonadales 135614|Xanthomonadales V Inner membrane protein involved in colicin E2 resistance creD - - ko:K06143 - - - - ko00000 - - - CreD DYD1_k127_6445948_7 1117318.PRUB_01444 3.944e-22 112.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,2Q0U2@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 DYD1_k127_6445948_4 1297570.MESS4_830313 1.597e-68 241.0 COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,43HT4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Inositol monophosphatase hisN - 3.1.3.15,3.1.3.25,3.1.3.93 ko:K01092,ko:K18649 ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070 M00026,M00114,M00131 R01185,R01186,R01187,R03013,R07674 RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P DYD1_k127_6445948_6 686340.Metal_2278 6.64e-49 176.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II DYD1_k127_6445948_1 1168065.DOK_19100 5.067e-170 541.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1J4I3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp DYD1_k127_6451206_2 1458357.BG58_28305 2.012e-16 92.0 COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,2WI17@28216|Betaproteobacteria,1KG8X@119060|Burkholderiaceae 28216|Betaproteobacteria D Protein of unknown function (DUF3300) - - - - - - - - - - - - DUF3300 DYD1_k127_6451206_0 627192.SLG_31380 4.109e-69 245.0 COG4886@1|root,COG4886@2|Bacteria,1N4KB@1224|Proteobacteria 1224|Proteobacteria S Planctomycete cytochrome C - - - - - - - - - - - - PSCyt1 DYD1_k127_6451206_1 566466.NOR53_2004 1.785e-53 189.0 COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase of the TIM-barrel fold fldW - 4.1.1.45,4.2.1.83 ko:K03392,ko:K10220 ko00362,ko00380,ko01100,ko01120,map00362,map00380,map01100,map01120 M00038 R04323,R04478 RC00498,RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_6477471_0 935840.JAEQ01000020_gene2336 3.166e-126 415.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA DYD1_k127_6477471_1 935840.JAEQ01000020_gene2336 3.211e-18 87.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA DYD1_k127_6482797_3 1121921.KB898706_gene2779 1.686e-19 93.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,2PNVR@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria U Preprotein translocase SecG subunit secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG DYD1_k127_6482797_2 396588.Tgr7_0984 1.038e-85 290.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1WW6U@135613|Chromatiales 135613|Chromatiales G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM DYD1_k127_6482797_0 697282.Mettu_3203 4.668e-164 528.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1XEX8@135618|Methylococcales 135618|Methylococcales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_6482797_1 396588.Tgr7_0981 5.394e-110 360.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales 135613|Chromatiales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD1_k127_6532118_1 396588.Tgr7_2763 5.621e-102 346.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales 135613|Chromatiales CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD1_k127_6532118_0 1198232.CYCME_0476 4.18e-140 454.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,45ZRX@72273|Thiotrichales 72273|Thiotrichales E Belongs to the peptidase M24B family - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 DYD1_k127_6549577_3 395493.BegalDRAFT_2360 4.387e-38 145.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,460FH@72273|Thiotrichales 72273|Thiotrichales J Belongs to the SUA5 family - - - - - - - - - - - - Sua5_yciO_yrdC DYD1_k127_6549577_2 583345.Mmol_0691 9.327e-55 202.0 COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,2KKUP@206350|Nitrosomonadales 206350|Nitrosomonadales S Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 DYD1_k127_6549577_0 1265313.HRUBRA_00023 5.961e-95 327.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1J4MQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA DYD1_k127_6549577_1 713586.KB900536_gene604 1.335e-59 214.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1WW3N@135613|Chromatiales 135613|Chromatiales D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves - - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB DYD1_k127_6549577_4 1049564.TevJSym_ah00710 1.56e-15 81.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1J4GT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_6560209_4 1247726.MIM_c16030 6.596e-45 169.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,3T2IU@506|Alcaligenaceae 28216|Betaproteobacteria I Fatty acid desaturase ole1 - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase DYD1_k127_6560209_1 1265313.HRUBRA_01216 8.389e-94 315.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1J5A0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD1_k127_6560209_0 1173027.Mic7113_4587 7.137e-158 520.0 COG0405@1|root,COG0405@2|Bacteria,1G14N@1117|Cyanobacteria,1H83V@1150|Oscillatoriales 1117|Cyanobacteria E PFAM Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD1_k127_6560209_3 1357272.AVEO02000194_gene200 6.914e-53 190.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1Z5I7@136849|Pseudomonas syringae group 1236|Gammaproteobacteria F Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0053,iSDY_1059.SDY_4064 CTP_transf_like DYD1_k127_6560209_5 765911.Thivi_2997 3.755e-36 147.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1WY3H@135613|Chromatiales 135613|Chromatiales L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle - - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 DYD1_k127_6560209_2 243924.LT42_24005 1.843e-73 259.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N DYD1_k127_6563360_1 1026882.MAMP_02635 1.286e-27 116.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,45ZWB@72273|Thiotrichales 72273|Thiotrichales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 DYD1_k127_6563360_0 443144.GM21_0554 2.595e-36 143.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria 1224|Proteobacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran DYD1_k127_6563360_2 395494.Galf_2665 7.458e-16 89.0 COG2199@1|root,COG3706@2|Bacteria,1QXRM@1224|Proteobacteria,2WH6B@28216|Betaproteobacteria 28216|Betaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - GGDEF,PAS_9 DYD1_k127_6563360_3 754477.Q7C_635 3.963e-08 62.0 2EC19@1|root,3360G@2|Bacteria,1PBYU@1224|Proteobacteria,1SD34@1236|Gammaproteobacteria,461FP@72273|Thiotrichales 72273|Thiotrichales S Peptidoglycan-binding protein, CsiV - - - - - - - - - - - - CsiV DYD1_k127_65813_4 1280947.HY30_15865 9.777e-40 154.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,43X6D@69657|Hyphomonadaceae 28211|Alphaproteobacteria CG alcohol dehydrogenase - - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 DYD1_k127_65813_3 1082931.KKY_2582 1.375e-47 183.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Dehydrogenase - - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 DYD1_k127_65813_0 314270.RB2083_766 1.288e-87 296.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,3ZHH4@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria O Glutathione S-transferase - - - - - - - - - - - - GST_C,GST_N,GST_N_3 DYD1_k127_65813_2 1120983.KB894576_gene3459 8.784e-58 213.0 COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TRAP transporter solute receptor TAXI family protein - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD1_k127_65813_1 472759.Nhal_0363 2.533e-86 299.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1X28I@135613|Chromatiales 135613|Chromatiales M Lysin motif - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD1_k127_6583114_2 1502850.FG91_00059 6.941e-05 51.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2U08D@28211|Alphaproteobacteria,2KD2V@204457|Sphingomonadales 204457|Sphingomonadales E Prolyl oligopeptidase - - - - - - - - - - - - Peptidase_S9 DYD1_k127_6583114_0 1265313.HRUBRA_01849 1.279e-173 569.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Dehydrogenase - - - - - - - - - - - - Cytochrome_CBB3,PQQ_2 DYD1_k127_6583114_1 314260.PB2503_04937 2.717e-100 343.0 COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria 28211|Alphaproteobacteria E peptidase S9A, prolyl oligopeptidase domain protein beta-propeller ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N DYD1_k127_661422_1 1348657.M622_02625 4.056e-36 139.0 COG2194@1|root,COG2194@2|Bacteria,1MWS7@1224|Proteobacteria,2VJHS@28216|Betaproteobacteria,2KUDG@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function (DUF1705) - - 2.7.8.42,2.7.8.43 ko:K03760,ko:K12975 ko00540,ko01503,map00540,map01503 M00722,M00723 R11204,R11205,R11555,R11556,R11557 RC00002,RC00017,RC00428 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1705,Sulfatase DYD1_k127_661422_0 1121013.P873_07225 1.217e-114 376.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1X33N@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C DYD1_k127_661422_3 1178482.BJB45_01755 2.705e-05 49.0 COG3630@1|root,COG3630@2|Bacteria,1NHYS@1224|Proteobacteria,1SGS8@1236|Gammaproteobacteria,1XM8S@135619|Oceanospirillales 135619|Oceanospirillales C Lyase and sodium transporter oadG - 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_gamma DYD1_k127_661422_2 1127673.GLIP_1463 1.085e-19 89.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,1RNG6@1236|Gammaproteobacteria,4659U@72275|Alteromonadaceae 1236|Gammaproteobacteria CI COG5016 Pyruvate oxaloacetate carboxyltransferase oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA DYD1_k127_6616594_2 1121013.P873_03985 9.254e-77 260.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales 135614|Xanthomonadales S FeS assembly SUF system protein SufT - - - - - - - - - - - - FeS_assembly_P DYD1_k127_6616594_3 1232410.KI421421_gene3305 8.306e-40 153.0 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,42TJ0@68525|delta/epsilon subdivisions,2WSKD@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine phosphatase superfamily (branch 1) - - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 DYD1_k127_6616594_1 1121374.KB891586_gene2496 5.378e-133 447.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria 1236|Gammaproteobacteria OU Signal peptide peptidase sppA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 DYD1_k127_6616594_0 1049564.TevJSym_aa02510 1.002e-143 473.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1J544@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM DYD1_k127_6616594_4 1123228.AUIH01000006_gene2239 1.292e-31 128.0 COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,1SD4H@1236|Gammaproteobacteria,1XM5N@135619|Oceanospirillales 135619|Oceanospirillales G TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ DYD1_k127_6616594_5 930169.B5T_03318 4.784e-16 82.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RUFU@1236|Gammaproteobacteria,1XJBV@135619|Oceanospirillales 135619|Oceanospirillales G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP DYD1_k127_6626467_1 404380.Gbem_1134 7.533e-191 606.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,43T96@69541|Desulfuromonadales 28221|Deltaproteobacteria G Phosphoglucomutase/phosphomannomutase, C-terminal domain algC - 5.4.2.2,5.4.2.8 ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_6626467_2 876269.ARWA01000001_gene2915 2.349e-158 509.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,3NA7I@45404|Beijerinckiaceae 28211|Alphaproteobacteria H Aminotransferase class-III bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_6626467_0 1033802.SSPSH_002108 5.313e-289 898.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H acetolactate synthase ilvI GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_6626467_3 580332.Slit_2403 9.11e-45 168.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,44VPP@713636|Nitrosomonadales 28216|Betaproteobacteria E ACT domain ilvH GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5,ALS_ss_C DYD1_k127_6654252_0 187272.Mlg_1485 1.53e-234 745.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales 135613|Chromatiales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V DYD1_k127_6669556_3 1387312.BAUS01000007_gene2261 9.488e-63 217.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,2KKYD@206350|Nitrosomonadales 206350|Nitrosomonadales C TIGRFAM formate dehydrogenase, alpha subunit - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_6,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD1_k127_6669556_5 384676.PSEEN1829 2.439e-09 61.0 2E4CR@1|root,32Z86@2|Bacteria,1NJVT@1224|Proteobacteria,1SFKZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S formate dehydrogenase - - 1.17.1.9 ko:K00126 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - FdsD DYD1_k127_6669556_0 1123399.AQVE01000026_gene2986 2.629e-135 442.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,1RPA1@1236|Gammaproteobacteria,46058@72273|Thiotrichales 72273|Thiotrichales C FMN-dependent dehydrogenase lldD - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh DYD1_k127_6669556_2 1246448.ANAZ01000020_gene2830 3.787e-77 267.0 COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4EFG2@85012|Streptosporangiales 201174|Actinobacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ DYD1_k127_6669556_4 1149133.ppKF707_1989 1.611e-22 111.0 COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,1RSQ1@1236|Gammaproteobacteria,1YETT@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD1_k127_6669556_1 1123393.KB891326_gene153 8.059e-101 338.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VP8B@28216|Betaproteobacteria,1KSE5@119069|Hydrogenophilales 119069|Hydrogenophilales EH chorismate binding enzyme - - - - - - - - - - - - Anth_synt_I_N,Chorismate_bind DYD1_k127_6674299_4 713587.THITH_02410 3.992e-33 134.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1WVUX@135613|Chromatiales 135613|Chromatiales M Lipid A biosynthesis lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD1_k127_6674299_2 1232683.ADIMK_1740 1.2e-42 175.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,467BW@72275|Alteromonadaceae 1236|Gammaproteobacteria M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase DYD1_k127_6674299_1 1439940.BAY1663_02501 8.463e-43 168.0 COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,1S4SG@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-Transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 DYD1_k127_6674299_0 1384054.N790_12970 5.118e-91 321.0 COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG4775 Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag,ShlB DYD1_k127_6674299_3 1469245.JFBG01000001_gene530 2.93e-39 153.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,Pyr_redox_2 DYD1_k127_6677061_3 396588.Tgr7_1078 5.088e-34 134.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1WW4C@135613|Chromatiales 135613|Chromatiales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase DYD1_k127_6677061_2 1027273.GZ77_14005 3.848e-34 135.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XK38@135619|Oceanospirillales 135619|Oceanospirillales FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hinT - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT DYD1_k127_6677061_0 1123073.KB899244_gene297 9.338e-78 265.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1X30Z@135614|Xanthomonadales 135614|Xanthomonadales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 DYD1_k127_6677061_1 1123393.KB891328_gene557 6.339e-36 142.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,1KRPW@119069|Hydrogenophilales 119069|Hydrogenophilales S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd DYD1_k127_6677061_4 247634.GPB2148_3807 2.027e-09 61.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1J4KC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5 DYD1_k127_6681689_5 472759.Nhal_2396 3.417e-13 69.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1WYKG@135613|Chromatiales 135613|Chromatiales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 DYD1_k127_6681689_0 1033802.SSPSH_003092 1.096e-76 262.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria 1236|Gammaproteobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C DYD1_k127_6681689_3 1500890.JQNL01000001_gene2861 2.394e-39 148.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1X6WF@135614|Xanthomonadales 135614|Xanthomonadales J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 DYD1_k127_6681689_2 519989.ECTPHS_13128 3.145e-45 167.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1WXYT@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 DYD1_k127_6681689_1 187272.Mlg_0473 9.017e-71 243.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1WXV2@135613|Chromatiales 135613|Chromatiales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 DYD1_k127_6681689_4 1121923.GPUN_2680 7.633e-39 147.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,4679B@72275|Alteromonadaceae 1236|Gammaproteobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p DYD1_k127_6681689_6 1283300.ATXB01000001_gene629 1.235e-06 51.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1XERY@135618|Methylococcales 135618|Methylococcales J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C DYD1_k127_6687958_1 550540.Fbal_3458 8.32e-36 138.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase ramA - 3.5.5.1 ko:K01501,ko:K11206 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase DYD1_k127_6687958_0 572477.Alvin_2520 5.082e-198 627.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD DYD1_k127_6703256_2 876044.IMCC3088_194 2.155e-15 78.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria,1J67A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G C4-dicarboxylate ABC transporter - - - - - - - - - - - - DctP DYD1_k127_6703256_1 1117647.M5M_08135 1.321e-36 146.0 COG3090@1|root,COG3090@2|Bacteria,1RJ8K@1224|Proteobacteria,1SA02@1236|Gammaproteobacteria 1236|Gammaproteobacteria G TRAP-type C4-dicarboxylate transport system small permease component - - - - - - - - - - - - DctQ DYD1_k127_6703256_0 876044.IMCC3088_196 1.846e-173 553.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1J5GJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Permease - - - - - - - - - - - - DctM DYD1_k127_6703256_3 435908.IDSA_09330 2.31e-14 80.0 COG5487@1|root,COG5487@2|Bacteria,1PCW1@1224|Proteobacteria,1T6ED@1236|Gammaproteobacteria,2QH12@267893|Idiomarinaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1328) - - - - - - - - - - - - DUF1328 DYD1_k127_6753276_0 519989.ECTPHS_06767 1.004e-117 396.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1WWT6@135613|Chromatiales 135613|Chromatiales M Surface antigen variable number - - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 DYD1_k127_6753276_1 441620.Mpop_2889 7.233e-05 49.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,1JTHU@119045|Methylobacteriaceae 28211|Alphaproteobacteria S TamB, inner membrane protein subunit of TAM complex tamB - - ko:K09800 - - - - ko00000,ko02000 - - - TamB DYD1_k127_6753878_1 1304275.C41B8_02162 1.768e-48 186.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase phoR GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 DYD1_k127_6753878_2 743721.Psesu_2051 2.617e-47 172.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1X316@135614|Xanthomonadales 135614|Xanthomonadales KT Two component response regulator for the phosphate regulon phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_6753878_4 765914.ThisiDRAFT_2326 1.04e-33 132.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1WVZG@135613|Chromatiales 135613|Chromatiales T phosphate regulon transcriptional regulatory protein PhoB - - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_6753878_3 713586.KB900536_gene638 1.16e-38 157.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1WX9X@135613|Chromatiales 135613|Chromatiales O PFAM Peptidase M22, glycoprotease - - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 DYD1_k127_6753878_0 519989.ECTPHS_03577 6.896e-72 249.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales 135613|Chromatiales L Helicase - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2 DYD1_k127_6754833_2 1288494.EBAPG3_13200 4.041e-24 105.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,3729N@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis ubiD - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_6754833_0 1300345.LF41_870 2.746e-171 549.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1X3E0@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 DYD1_k127_6754833_1 416348.Hlac_2205 1.916e-43 170.0 COG0114@1|root,arCOG01749@2157|Archaea,2XT2J@28890|Euryarchaeota,23T2J@183963|Halobacteria 183963|Halobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 DYD1_k127_675933_0 314278.NB231_13346 1.482e-184 623.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg DYD1_k127_6819226_3 366649.XFF4834R_chr10820 8.502e-22 97.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1SA8G@1236|Gammaproteobacteria,1XC86@135614|Xanthomonadales 135614|Xanthomonadales H Molybdopterin-converting factor chain 2 moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE DYD1_k127_6819226_4 1163408.UU9_06279 1.863e-15 82.0 COG1977@1|root,COG1977@2|Bacteria,1NAHE@1224|Proteobacteria,1SE6D@1236|Gammaproteobacteria,1X8CW@135614|Xanthomonadales 135614|Xanthomonadales H Molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD1_k127_6819226_2 929562.Emtol_2311 1.139e-53 193.0 COG0315@1|root,COG0315@2|Bacteria,4NHA0@976|Bacteroidetes,47PU9@768503|Cytophagia 976|Bacteroidetes H MoaC family moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC DYD1_k127_6819226_0 1045855.DSC_11960 8.068e-118 393.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1X46A@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM DYD1_k127_6819226_1 443152.MDG893_04844 2.096e-74 259.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,465ZY@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG2230 Cyclopropane fatty acid synthase and related methyltransferases cfa2 - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS DYD1_k127_6819415_0 639283.Snov_2812 1.429e-298 922.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,3EYAB@335928|Xanthobacteraceae 28211|Alphaproteobacteria F Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD1_k127_6819415_1 187272.Mlg_2696 1.136e-22 97.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1WYU9@135613|Chromatiales 135613|Chromatiales CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - - - - - - - - - - Iron_traffic DYD1_k127_6824844_0 697282.Mettu_4101 3.918e-44 171.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria,1XGCF@135618|Methylococcales 135618|Methylococcales C XdhC and CoxI family - - - - - - - - - - - - XdhC_C,XdhC_CoxI DYD1_k127_6831204_0 686340.Metal_1012 1.793e-135 439.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1XE4R@135618|Methylococcales 135618|Methylococcales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM DYD1_k127_6831204_1 1116472.MGMO_161c00020 1.93e-61 216.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1XDJW@135618|Methylococcales 135618|Methylococcales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB DYD1_k127_6843858_4 314278.NB231_15073 7.464e-19 88.0 COG0778@1|root,COG0778@2|Bacteria 2|Bacteria C coenzyme F420-1:gamma-L-glutamate ligase activity yfhC - - - - - - - - - - - Nitroreductase DYD1_k127_6843858_2 1260251.SPISAL_01235 1.996e-34 136.0 2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6843858_0 323261.Noc_2144 2.278e-162 533.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RSM7@1236|Gammaproteobacteria,1WXFW@135613|Chromatiales 135613|Chromatiales S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 DYD1_k127_6843858_1 1442599.JAAN01000023_gene1789 4.792e-59 217.0 COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,1X60Y@135614|Xanthomonadales 135614|Xanthomonadales F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase DYD1_k127_6843858_3 81824.XP_001743982.1 2.442e-25 107.0 KOG1406@1|root,KOG1406@2759|Eukaryota,38CKQ@33154|Opisthokonta 33154|Opisthokonta I propanoyl-CoA C-acyltransferase activity - - - - - - - - - - - - Thiolase_C,Thiolase_N DYD1_k127_6844225_0 1297742.A176_01884 2.808e-78 284.0 COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,42MX2@68525|delta/epsilon subdivisions,2WIUV@28221|Deltaproteobacteria 28221|Deltaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_6844225_1 926550.CLDAP_37410 1.74e-49 181.0 COG1136@1|root,COG1136@2|Bacteria,2G8HT@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_6875515_4 391625.PPSIR1_35122 7.255e-74 251.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2YU99@29|Myxococcales 28221|Deltaproteobacteria H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN DYD1_k127_6875515_2 1161401.ASJA01000022_gene134 2.525e-121 398.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,43WHR@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD1_k127_6875515_0 324602.Caur_0168 5.914e-201 635.0 COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi,3753P@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase DYD1_k127_6875515_3 290397.Adeh_1979 9.959e-81 272.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42QN7@68525|delta/epsilon subdivisions,2WP27@28221|Deltaproteobacteria,2YVXG@29|Myxococcales 28221|Deltaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD1_k127_6875515_1 84531.JMTZ01000006_gene3502 3.009e-127 414.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1X4UN@135614|Xanthomonadales 135614|Xanthomonadales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD1_k127_6896529_0 1198452.Jab_2c14240 4.766e-107 355.0 COG3534@1|root,COG3534@2|Bacteria,1PPWJ@1224|Proteobacteria,2VIS5@28216|Betaproteobacteria,476UZ@75682|Oxalobacteraceae 28216|Betaproteobacteria G Alpha-L-arabinofuranosidase C-terminus asdII - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C DYD1_k127_6896529_1 1479237.JMLY01000001_gene1127 5.859e-37 153.0 2DKFZ@1|root,309D6@2|Bacteria,1REQQ@1224|Proteobacteria,1S796@1236|Gammaproteobacteria,466PI@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4382) - - - - - - - - - - - - DUF4382 DYD1_k127_6939760_3 1120953.AUBH01000004_gene3047 5.495e-05 48.0 COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria,46BP8@72275|Alteromonadaceae 1236|Gammaproteobacteria T Protein phosphatase 2A homologues, catalytic domain. - - - - - - - - - - - - Metallophos DYD1_k127_6939760_1 1323663.AROI01000009_gene3410 5.693e-75 261.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria P sulfurtransferase sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD1_k127_6939760_2 1469245.JFBG01000037_gene1851 5.602e-66 229.0 COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,1S43F@1236|Gammaproteobacteria 1236|Gammaproteobacteria I dehydratase - - 4.2.1.56 ko:K18290 ko00660,map00660 - R02491 RC00730 ko00000,ko00001,ko01000 - - - MaoC_dehydratas DYD1_k127_6939760_0 243233.MCA0335 3.592e-229 719.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PE6F@1224|Proteobacteria,1RWQP@1236|Gammaproteobacteria,1XDNM@135618|Methylococcales 135618|Methylococcales CEH 2 iron, 2 sulfur cluster binding - - - - - - - - - - - - Pyr_redox_2 DYD1_k127_6942396_0 314278.NB231_17233 1.16e-127 417.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1WXPZ@135613|Chromatiales 135613|Chromatiales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,HTH_42,Helicase_C DYD1_k127_6942396_1 1116472.MGMO_26c00130 9.192e-116 378.0 COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria,1XE77@135618|Methylococcales 135618|Methylococcales V (ABC) transporter - - - - - - - - - - - - - DYD1_k127_6942396_2 1232410.KI421428_gene1127 7.772e-44 171.0 COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria,42UB4@68525|delta/epsilon subdivisions,2WQJ3@28221|Deltaproteobacteria,43U5E@69541|Desulfuromonadales 28221|Deltaproteobacteria S Rhomboid family - - - - - - - - - - - - Rhomboid DYD1_k127_6942396_3 1123393.KB891332_gene2705 5.384e-19 92.0 2EH48@1|root,338P5@2|Bacteria,1NFS9@1224|Proteobacteria,2W6NA@28216|Betaproteobacteria,1KT6V@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - DYD1_k127_6957787_3 1007104.SUS17_2461 6.415e-65 229.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales 204457|Sphingomonadales G glucose sorbosone - - - - - - - - - - - - GSDH DYD1_k127_6957787_2 991905.SL003B_3169 1.071e-70 248.0 COG3473@1|root,COG3473@2|Bacteria,1RA2D@1224|Proteobacteria,2U5UC@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Asp Glu hydantoin racemase - - 4.1.1.76,5.2.1.1 ko:K01799,ko:K06033 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - - DYD1_k127_6957787_0 1379270.AUXF01000002_gene1148 1.909e-220 700.0 COG4993@1|root,COG4993@2|Bacteria,1ZSSJ@142182|Gemmatimonadetes 2|Bacteria G PQQ-like domain - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 DYD1_k127_6957787_6 909613.UO65_4925 1.216e-07 63.0 COG0346@1|root,COG0346@2|Bacteria,2GN2E@201174|Actinobacteria,4DXST@85010|Pseudonocardiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 1.13.11.14 ko:K10621 ko00362,ko00622,ko01120,ko01220,map00362,map00622,map01120,map01220 M00539 R01507,R05248 RC00387,RC01308 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase DYD1_k127_6957787_4 247633.GP2143_17796 5.063e-50 190.0 28NHI@1|root,2ZBJA@2|Bacteria,1RCPZ@1224|Proteobacteria,1ST6N@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6957787_1 247633.GP2143_17791 2.295e-81 280.0 28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,1SNXF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6957787_5 247633.GP2143_18131 2.347e-35 138.0 2C42J@1|root,3359Y@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6970382_1 686340.Metal_0980 8.106e-64 225.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1XETF@135618|Methylococcales 135618|Methylococcales F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK DYD1_k127_6970382_0 472759.Nhal_0527 2.219e-155 512.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales 135613|Chromatiales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran DYD1_k127_6970382_3 472759.Nhal_0528 5.328e-28 117.0 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1WYEK@135613|Chromatiales 135613|Chromatiales U PFAM Biopolymer transport protein ExbD TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD DYD1_k127_6970382_2 391615.ABSJ01000037_gene957 9.565e-33 130.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1J9XP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U MotA/TolQ/ExbB proton channel family exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB DYD1_k127_6980484_1 765913.ThidrDRAFT_2848 1.281e-84 284.0 COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1WW96@135613|Chromatiales 135613|Chromatiales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - ko:K02474 ko00520,map00520 - R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_6980484_0 203122.Sde_2020 3.314e-198 630.0 COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,464PD@72275|Alteromonadaceae 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaB GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - ko:K03314 - - - - ko00000,ko02000 2.A.34.1 - iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372 NhaB DYD1_k127_6980484_2 1026882.MAMP_01246 9.476e-80 273.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,460CA@72273|Thiotrichales 72273|Thiotrichales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T DYD1_k127_6980484_3 1177179.A11A3_06710 2.499e-45 165.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales 135619|Oceanospirillales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H DYD1_k127_6985667_0 627192.SLG_06600 6.79e-54 198.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2K3KA@204457|Sphingomonadales 28211|Alphaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD1_k127_6985667_1 1128912.GMES_4108 3.16e-21 106.0 COG0810@1|root,COG0810@2|Bacteria,1RGHP@1224|Proteobacteria,1S54W@1236|Gammaproteobacteria,468YG@72275|Alteromonadaceae 1236|Gammaproteobacteria U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - Peptidase_M56,TonB_C DYD1_k127_6985667_2 1453501.JELR01000001_gene3236 4.177e-14 85.0 2C612@1|root,32RGH@2|Bacteria,1RGYZ@1224|Proteobacteria,1S8MM@1236|Gammaproteobacteria,46BBZ@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_700476_3 469383.Cwoe_4435 2.967e-11 66.0 COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4CR1A@84995|Rubrobacteria 84995|Rubrobacteria F PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_1 DYD1_k127_700476_0 118163.Ple7327_0161 9.75e-195 619.0 COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3VIAJ@52604|Pleurocapsales 1117|Cyanobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.39,1.2.1.79,1.2.1.8 ko:K00130,ko:K00135,ko:K00146,ko:K22187 ko00040,ko00250,ko00260,ko00310,ko00350,ko00360,ko00643,ko00650,ko00760,ko01100,ko01120,map00040,map00250,map00260,map00310,map00350,map00360,map00643,map00650,map00760,map01100,map01120 M00027,M00555 R00713,R00714,R02401,R02536,R02565,R02566,R11768 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_700476_1 1121033.AUCF01000016_gene5484 8.402e-133 429.0 COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria,2JU12@204441|Rhodospirillales 204441|Rhodospirillales S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_700476_2 391625.PPSIR1_12693 1.817e-43 161.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,42SXE@68525|delta/epsilon subdivisions,2WUXE@28221|Deltaproteobacteria,2YUTE@29|Myxococcales 28221|Deltaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799,ko:K11209 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N DYD1_k127_718329_0 1265313.HRUBRA_00830 6.545e-208 662.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase dnaE GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon DYD1_k127_753239_3 1234364.AMSF01000085_gene2897 1.591e-32 128.0 COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,1RYFM@1236|Gammaproteobacteria,1X58P@135614|Xanthomonadales 135614|Xanthomonadales M Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_753239_1 1144312.PMI09_01659 9.293e-72 249.0 COG0500@1|root,COG2226@2|Bacteria,1Q6ZD@1224|Proteobacteria,2VD3D@28211|Alphaproteobacteria,4BA71@82115|Rhizobiaceae 28211|Alphaproteobacteria Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11 DYD1_k127_753239_4 269797.Mbar_A0368 2.915e-06 60.0 COG1287@1|root,arCOG02043@2157|Archaea,2XX8Q@28890|Euryarchaeota,2NADZ@224756|Methanomicrobia 224756|Methanomicrobia M Oligosaccharyl transferase STT3 subunit - - 2.4.99.18 ko:K07151 ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141 M00072 R04216,R05976 RC00005,RC00482 ko00000,ko00001,ko00002,ko01000,ko01003 - GT66 - STT3 DYD1_k127_753239_0 522306.CAP2UW1_2780 1.046e-177 579.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,2VH5K@28216|Betaproteobacteria 28216|Betaproteobacteria KLT Serine threonine protein prkC2 - 2.7.11.1,3.1.3.16 ko:K01090,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PP2C_2,Pkinase,TPR_16,TPR_19,TPR_8 DYD1_k127_753239_2 159087.Daro_0825 3.49e-49 176.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI6Q@28216|Betaproteobacteria,2KUW4@206389|Rhodocyclales 206389|Rhodocyclales P MFS/sugar transport protein narK - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 DYD1_k127_754324_1 349124.Hhal_1036 8.203e-133 439.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales 135613|Chromatiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_754324_0 426117.M446_6299 8.353e-174 554.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,1JTBI@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM biotin lipoyl attachment domain-containing protein lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim DYD1_k127_767479_2 1121921.KB898706_gene2722 3.71e-36 144.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2PNZB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria NU Pilin (bacterial filament) pilA - - ko:K02650,ko:K02655 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD1_k127_767479_0 1198232.CYCME_0641 1.464e-110 364.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,460H9@72273|Thiotrichales 72273|Thiotrichales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA DYD1_k127_767479_1 396588.Tgr7_3001 8.542e-94 319.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1WZSA@135613|Chromatiales 135613|Chromatiales O cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA DYD1_k127_767479_3 1123256.KB907939_gene299 8.857e-23 106.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,1X800@135614|Xanthomonadales 135614|Xanthomonadales S signal sequence binding - - - - - - - - - - - - SCO1-SenC DYD1_k127_767479_4 686340.Metal_1813 1.269e-15 83.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1XEXY@135618|Methylococcales 135618|Methylococcales S SURF1-like protein - - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 DYD1_k127_778648_1 105559.Nwat_1437 1.275e-12 75.0 2EB0T@1|root,3351P@2|Bacteria,1NCHM@1224|Proteobacteria,1SJ6Z@1236|Gammaproteobacteria,1X1WX@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD1_k127_778648_0 1415780.JPOG01000001_gene1246 0.0 1021.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1X4NM@135614|Xanthomonadales 135614|Xanthomonadales C E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr DYD1_k127_823240_1 765914.ThisiDRAFT_0354 6.802e-94 314.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis DYD1_k127_823240_0 743721.Psesu_2005 8.137e-131 427.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1X3CE@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD1_k127_823240_2 1033802.SSPSH_002254 4.456e-40 152.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M ErfK YbiS YcfS YnhG family protein erfK - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - YkuD DYD1_k127_838181_2 627192.SLG_31400 3.863e-51 186.0 COG2960@1|root,COG2960@2|Bacteria,1RGT9@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH DYD1_k127_838181_0 627192.SLG_31420 2.332e-206 665.0 COG0551@1|root,COG0551@2|Bacteria,1NU8S@1224|Proteobacteria,2TWWM@28211|Alphaproteobacteria,2K3KC@204457|Sphingomonadales 204457|Sphingomonadales L Protein of unknown function (DUF1587) - - - - - - - - - - - - PSCyt3,PSD2,PSD3,PSD4,PSD5 DYD1_k127_838181_4 627192.SLG_31390 7.303e-11 63.0 COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT ankyrin repeat - - - ko:K15503 - - - - ko00000,ko01009,ko03400 - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5 DYD1_k127_838181_1 627192.SLG_31390 9.838e-101 343.0 COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,2UA2F@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT ankyrin repeat - - - ko:K15503 - - - - ko00000,ko01009,ko03400 - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5 DYD1_k127_838181_5 498848.TaqDRAFT_5267 0.0002523 53.0 COG0346@1|root,COG0346@2|Bacteria,1WJ1B@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - 1.13.11.2 ko:K00446 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase DYD1_k127_838181_3 1472418.BBJC01000004_gene1788 5.059e-13 80.0 2CBAE@1|root,31814@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_842967_1 1121918.ARWE01000001_gene946 3.403e-85 289.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WU90@28221|Deltaproteobacteria,43T4I@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Type II secretion system (T2SS), protein E, N-terminal domain - - - ko:K12276 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - T2SSE,T2SSE_N DYD1_k127_842967_0 1109445.AGSX01000129_gene2738 1.408e-110 370.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,1Z2MD@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria NU COG1459 Type II secretory pathway, component PulF mshG - - ko:K02505,ko:K12278 - - - - ko00000,ko02044 - - - T2SSF DYD1_k127_842967_4 1121918.ARWE01000001_gene948 3.413e-15 82.0 COG2165@1|root,COG2165@2|Bacteria,1PV8S@1224|Proteobacteria,4337B@68525|delta/epsilon subdivisions,2WXN0@28221|Deltaproteobacteria,43VR8@69541|Desulfuromonadales 28221|Deltaproteobacteria NU general secretion pathway protein - - - - - - - - - - - - - DYD1_k127_842967_3 1123368.AUIS01000011_gene1135 9.045e-18 95.0 COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,1SDMJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Type II secretory pathway, pseudopilin PulG mshA - - ko:K10924 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl DYD1_k127_842967_2 1439940.BAY1663_02053 5.189e-18 87.0 COG4970@1|root,COG4970@2|Bacteria,1R1TK@1224|Proteobacteria,1T5AM@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl DYD1_k127_864286_8 1288494.EBAPG3_14440 1.465e-18 89.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2VWSZ@28216|Betaproteobacteria,3731R@32003|Nitrosomonadales 28216|Betaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_864286_0 391589.RGAI101_4098 2.548e-156 505.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2P1VQ@2433|Roseobacter 28211|Alphaproteobacteria O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD1_k127_864286_10 1172185.KB911519_gene3910 5.854e-06 55.0 COG3631@1|root,COG3631@2|Bacteria,2INUG@201174|Actinobacteria,4G27G@85025|Nocardiaceae 201174|Actinobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_4 DYD1_k127_864286_6 1122139.KB907867_gene1149 4.046e-43 164.0 COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,1RQPX@1236|Gammaproteobacteria,1XKJG@135619|Oceanospirillales 135619|Oceanospirillales J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 DYD1_k127_864286_2 1173028.ANKO01000244_gene3949 1.603e-98 329.0 COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales 1117|Cyanobacteria S Phenazine biosynthesis protein - - - - - - - - - - - - PhzC-PhzF DYD1_k127_864286_3 489825.LYNGBM3L_30420 9.5e-76 267.0 COG0500@1|root,COG2226@2|Bacteria,1GQ2Q@1117|Cyanobacteria 1117|Cyanobacteria Q Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 DYD1_k127_864286_5 1245471.PCA10_34900 6.452e-50 188.0 COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,1S6J5@1236|Gammaproteobacteria,1YGB9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF1993) - - - ko:K09983 - - - - ko00000 - - - DUF1993 DYD1_k127_864286_7 555793.WSK_3235 2.067e-36 151.0 2EVK9@1|root,33P0C@2|Bacteria,1P9RH@1224|Proteobacteria,2UVJR@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_864286_4 1304275.C41B8_10570 2.872e-61 217.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0178 family yaiI - - ko:K09768 - - - - ko00000 - - - DUF188 DYD1_k127_864286_1 1265313.HRUBRA_02132 5.644e-102 344.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Dehydrogenase - - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD1_k127_872_0 1231392.OCGS_0988 1.644e-150 487.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM DYD1_k127_872_2 880070.Cycma_2548 4.25e-15 80.0 2E6K6@1|root,3316Y@2|Bacteria,4NT3A@976|Bacteroidetes,47SXK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_872_1 502025.Hoch_6396 8.888e-19 93.0 2DBMC@1|root,2Z9YC@2|Bacteria,1PY40@1224|Proteobacteria,43E0Z@68525|delta/epsilon subdivisions,2WZDV@28221|Deltaproteobacteria,2Z1X8@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_881589_2 1123400.KB904758_gene2390 8.493e-46 169.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,45ZQ9@72273|Thiotrichales 72273|Thiotrichales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_881589_0 713586.KB900536_gene3049 2.658e-226 723.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, chain G - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD1_k127_881589_1 519989.ECTPHS_07062 1.02e-84 284.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1WWH3@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB DYD1_k127_886216_1 420662.Mpe_A1225 1.728e-41 156.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,2VZ4H@28216|Betaproteobacteria,1KN47@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 DYD1_k127_886216_4 498211.CJA_3317 1.59e-27 122.0 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria,1FFS9@10|Cellvibrio 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_10,TPR_12,TPR_16,TPR_6,TPR_8 DYD1_k127_886216_5 864051.BurJ1DRAFT_1739 8.592e-15 82.0 2AHZN@1|root,318CZ@2|Bacteria,1Q06K@1224|Proteobacteria,2W4WA@28216|Betaproteobacteria,1KNW5@119065|unclassified Burkholderiales 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_886216_0 396588.Tgr7_0539 3.167e-81 277.0 COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1X07Q@135613|Chromatiales 135613|Chromatiales U PFAM MotA TolQ ExbB proton channel - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB DYD1_k127_886216_2 1049564.TevJSym_au00050 3.273e-39 152.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,1JAY5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD DYD1_k127_886216_3 1049564.TevJSym_au00060 3.512e-39 152.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,1JAUR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD DYD1_k127_886216_6 1318628.MARLIPOL_04535 2.19e-10 68.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - DYD1_k127_901232_1 452637.Oter_2862 5.023e-09 65.0 COG0457@1|root,COG0457@2|Bacteria 452637.Oter_2862|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_901232_0 1227261.HMPREF0043_01903 7.314e-77 266.0 COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4D63Y@85005|Actinomycetales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_901232_2 1423321.AS29_09070 2.488e-08 61.0 COG0842@1|root,COG0842@2|Bacteria,1UYSF@1239|Firmicutes,4HEYE@91061|Bacilli,1ZCKQ@1386|Bacillus 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 DYD1_k127_908539_3 1134474.O59_000978 1.26e-06 54.0 28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,1RY8I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S s1 p1 nuclease - - 3.1.30.1 ko:K05986 - - - - ko00000,ko01000 - - - S1-P1_nuclease DYD1_k127_908539_1 472759.Nhal_3504 8.044e-123 407.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1WX73@135613|Chromatiales 135613|Chromatiales M PFAM Three-deoxy-D-manno-octulosonic-acid transferase - - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N,Kdo DYD1_k127_908539_0 1313301.AUGC01000003_gene2100 1.438e-127 416.0 COG0176@1|root,COG2905@1|root,COG0176@2|Bacteria,COG2905@2|Bacteria,4NIUX@976|Bacteroidetes 976|Bacteroidetes GT Transaldolase/Fructose-6-phosphate aldolase - - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - CBS,TAL_FSA DYD1_k127_908539_2 1313301.AUGC01000003_gene2099 1.558e-113 370.0 COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes 976|Bacteroidetes M Belongs to the KdsA family - - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 DYD1_k127_929006_0 493475.GARC_2328 6.962e-207 655.0 COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria,465QG@72275|Alteromonadaceae 1236|Gammaproteobacteria M cytochrome C peroxidase - - - - - - - - - - - - - DYD1_k127_929006_1 1042377.AFPJ01000036_gene1223 4.557e-83 293.0 COG0457@1|root,COG0457@2|Bacteria 1042377.AFPJ01000036_gene1223|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_93144_0 1134474.O59_000562 3.133e-112 383.0 28N9P@1|root,2ZBDN@2|Bacteria,1R70P@1224|Proteobacteria,1RQ5R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3592) - - - - - - - - - - - - DUF3592 DYD1_k127_950465_2 1385515.N791_02660 3.236e-35 138.0 COG3791@1|root,COG3791@2|Bacteria,1N0KM@1224|Proteobacteria,1SA6W@1236|Gammaproteobacteria,1XB4Q@135614|Xanthomonadales 135614|Xanthomonadales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD1_k127_950465_1 1122197.ATWI01000008_gene3289 2.828e-55 198.0 COG0346@1|root,COG0346@2|Bacteria,1RIQG@1224|Proteobacteria,1S409@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glyoxalase - - - - - - - - - - - - Glyoxalase DYD1_k127_950465_0 1402135.SUH3_05570 9.134e-152 489.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3ZVB4@60136|Sulfitobacter 28211|Alphaproteobacteria IQ Catalyzes the formation of malonyl-CoA from malonate and CoA - - - ko:K18661 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C DYD1_k127_983967_1 1254432.SCE1572_07650 1.314e-54 195.0 COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase - - 4.1.2.44 ko:K15513 ko00362,map00362 - R09556 RC03426 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_983967_0 1038860.AXAP01000010_gene7746 9.092e-225 704.0 COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria,3JSI1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S benzoyl-CoA oxygenase boxB - 1.14.13.208 ko:K15512 ko00362,map00362 - R09555 RC01739 ko00000,ko00001,ko01000 - - - - DYD1_k127_983967_2 62928.azo3053 3.914e-16 79.0 294JI@1|root,2ZRZ3@2|Bacteria,1REGD@1224|Proteobacteria,2VRDG@28216|Betaproteobacteria,2KYGP@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function (DUF4863) - - - - - - - - - - - - DUF4863 ## 2229 queries scanned ## Total time (seconds): 8.6338632106781 ## Rate: 258.17 q/s