## Sun Mar 16 07:43:45 2025 ## emapper-2.1.9 ## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD1_bin.73.fa -m mmseqs --itype genome -o DYD1_bin.73 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD1_bin.73 --cpu 8 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs DYD1_k127_1036039_2 865937.Gilli_0474 1.608e-18 91.0 COG3059@1|root,COG3059@2|Bacteria,4NNX8@976|Bacteroidetes,1I2AZ@117743|Flavobacteriia 976|Bacteroidetes S membrane - - - - - - - - - - - - DUF417,DoxX DYD1_k127_1036039_1 765952.PUV_26380 1.225e-82 285.0 COG2269@1|root,COG2269@2|Bacteria,2JFTW@204428|Chlamydiae 204428|Chlamydiae J tRNA synthetases class II (D, K and N) genX - - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 DYD1_k127_1036039_0 331113.SNE_A04080 5.802e-114 371.0 COG2820@1|root,COG2820@2|Bacteria,2JFWB@204428|Chlamydiae 204428|Chlamydiae F AMP nucleosidase amn - 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - PNP_UDP_1 DYD1_k127_1165722_2 331113.SNE_A11490 9.349e-105 347.0 COG1039@1|root,COG1039@2|Bacteria,2JFW4@204428|Chlamydiae 204428|Chlamydiae L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC - 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII DYD1_k127_1165722_3 331113.SNE_A11500 3.132e-43 161.0 COG1426@1|root,COG1426@2|Bacteria,2JG6D@204428|Chlamydiae 204428|Chlamydiae S Helix-turn-helix domain yfgA - - - - - - - - - - - HTH_25 DYD1_k127_1165722_0 331113.SNE_A11530 1.16e-213 678.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2JFPX@204428|Chlamydiae 204428|Chlamydiae KLT Together with the serine threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth pkn1 - - - - - - - - - - - FGE-sulfatase,Pkinase DYD1_k127_1165722_4 765952.PUV_12520 3.153e-37 145.0 COG0394@1|root,COG0394@2|Bacteria,2JG5M@204428|Chlamydiae 204428|Chlamydiae T Low molecular weight protein-tyrosine-phosphatase - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc DYD1_k127_1165722_1 331113.SNE_A11560 1.893e-143 460.0 COG0761@1|root,COG0761@2|Bacteria,2JFVQ@204428|Chlamydiae 204428|Chlamydiae IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB DYD1_k127_1173899_2 938289.CAJN020000002_gene766 5.362e-46 181.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,268DU@186813|unclassified Clostridiales 186801|Clostridia J Psort location Cytoplasmic, score 10.00 hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD1_k127_1173899_1 765952.PUV_06200 2.248e-50 191.0 COG1126@1|root,COG1126@2|Bacteria,2JH6Q@204428|Chlamydiae 204428|Chlamydiae E ABC transporter glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran DYD1_k127_1173899_3 387631.Asulf_00789 2.906e-32 134.0 COG0765@1|root,arCOG01798@2157|Archaea,2XV8Y@28890|Euryarchaeota 28890|Euryarchaeota P amino acid ABC transporter glnP - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 DYD1_k127_1173899_6 273068.TTE0512 1.748e-24 113.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,42F7E@68295|Thermoanaerobacterales 186801|Clostridia ET PFAM Extracellular solute-binding protein, family 3 artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD1_k127_1173899_7 1463841.JOIR01000020_gene3394 7.688e-18 88.0 COG4538@1|root,COG4538@2|Bacteria,2IMZM@201174|Actinobacteria 201174|Actinobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 DYD1_k127_1173899_4 1123073.KB899241_gene3328 4.134e-29 128.0 COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,1SB4S@1236|Gammaproteobacteria,1X6MG@135614|Xanthomonadales 135614|Xanthomonadales EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_1173899_0 1120999.JONM01000003_gene2597 2.859e-111 370.0 COG2175@1|root,COG2175@2|Bacteria,1NFYT@1224|Proteobacteria,2W4YB@28216|Betaproteobacteria 28216|Betaproteobacteria Q Taurine catabolism dioxygenase TauD, TfdA family - - - - - - - - - - - - TauD DYD1_k127_1173899_5 2754.EH55_02505 1.588e-26 119.0 COG3382@1|root,COG3382@2|Bacteria,3TB4A@508458|Synergistetes 508458|Synergistetes S B3 4 domain - - - - - - - - - - - - B3_4 DYD1_k127_1173899_8 1121430.JMLG01000001_gene2196 4.182e-09 65.0 COG0834@1|root,COG0834@2|Bacteria,1UFZS@1239|Firmicutes,24FKA@186801|Clostridia,2652X@186807|Peptococcaceae 186801|Clostridia ET PFAM Extracellular solute-binding protein, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD1_k127_118552_2 234267.Acid_3421 3.862e-13 74.0 COG0791@1|root,COG0791@2|Bacteria,3Y5IG@57723|Acidobacteria 57723|Acidobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60,SPOR DYD1_k127_118552_1 1185653.A1A1_13357 3.15e-28 124.0 COG0463@1|root,COG0463@2|Bacteria,1TQ8C@1239|Firmicutes,4HDD4@91061|Bacilli,26EGE@186818|Planococcaceae 91061|Bacilli M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,GtrA DYD1_k127_1198474_1 765952.PUV_10580 1.579e-47 180.0 COG1388@1|root,COG1388@2|Bacteria,2JGB6@204428|Chlamydiae 204428|Chlamydiae M Lysin motif - - - - - - - - - - - - LysM DYD1_k127_1198474_2 71421.HI_1000 1.353e-19 91.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,1Y901@135625|Pasteurellales 135625|Pasteurellales S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic DYD1_k127_1198474_0 1157490.EL26_03800 3.844e-86 301.0 COG1164@1|root,COG1164@2|Bacteria,1U8XY@1239|Firmicutes,4HEV8@91061|Bacilli 91061|Bacilli E Peptidase M3A and M3B thimet oligopeptidase F - - - - - - - - - - - - Peptidase_M2,Peptidase_M3 DYD1_k127_1205539_0 331113.SNE_A12250 6.857e-91 313.0 COG3202@1|root,COG3202@2|Bacteria 2|Bacteria C ATP:ADP antiporter activity - - - ko:K03301 - - - - ko00000 2.A.12 - - TLC DYD1_k127_1205539_1 331113.SNE_A12270 0.0003284 46.0 COG1078@1|root,COG1078@2|Bacteria,2JHB7@204428|Chlamydiae 204428|Chlamydiae S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06885 - - - - ko00000 - - - HD DYD1_k127_1213513_1 1444711.CCJF01000005_gene647 6.252e-26 117.0 2C2FJ@1|root,32RAD@2|Bacteria,2JG5S@204428|Chlamydiae 204428|Chlamydiae - - CP_1044 - - - - - - - - - - - - DYD1_k127_1213513_0 331113.SNE_A02930 3.368e-73 256.0 COG4669@1|root,COG4669@2|Bacteria,2JFMR@204428|Chlamydiae 204428|Chlamydiae U Type III sctJ - - ko:K03222 ko03070,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 - - YscJ_FliF DYD1_k127_1249227_1 765952.PUV_06060 1.363e-80 277.0 COG1420@1|root,COG1420@2|Bacteria,2JFK0@204428|Chlamydiae 204428|Chlamydiae K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA DYD1_k127_1249227_2 1444711.CCJF01000005_gene742 1.614e-46 173.0 COG0576@1|root,COG0576@2|Bacteria,2JG6C@204428|Chlamydiae 204428|Chlamydiae O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE DYD1_k127_1249227_0 331113.SNE_A05330 3.728e-314 971.0 COG0443@1|root,COG0443@2|Bacteria,2JFEI@204428|Chlamydiae 204428|Chlamydiae O Heat shock 70 kDa protein dnaK GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD1_k127_1252626_0 765952.PUV_22680 7.6e-111 366.0 COG0276@1|root,COG0276@2|Bacteria,2JGXV@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase DYD1_k127_1252626_1 331113.SNE_A02960 6.779e-78 272.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_1258348_1 247490.KSU1_C1303 2.535e-71 249.0 COG0366@1|root,COG0366@2|Bacteria,2IYAN@203682|Planctomycetes 203682|Planctomycetes G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 DYD1_k127_1258348_2 1502852.FG94_03692 0.0006963 48.0 COG3391@1|root,COG3391@2|Bacteria,1PGUU@1224|Proteobacteria,2WAW5@28216|Betaproteobacteria,476SP@75682|Oxalobacteraceae 28216|Betaproteobacteria S NHL repeat - - - - - - - - - - - - NHL DYD1_k127_1258348_0 390874.Tpet_0358 1.187e-137 441.0 COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,2GBZA@200918|Thermotogae 200918|Thermotogae F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Methyltransf_25 DYD1_k127_1300171_1 586416.GZ22_00780 7.772e-28 117.0 COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli 91061|Bacilli O Required for disulfide bond formation in some proteins bdbC - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB DYD1_k127_1300171_2 227941.CCA_00588 3.787e-18 93.0 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process bdbD - - - - - - - - - - - Thioredoxin_4 DYD1_k127_1300171_3 159087.Daro_1036 0.0003881 44.0 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,2KUQN@206389|Rhodocyclales 206389|Rhodocyclales K Crp Fnr family transcriptional regulator - - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding DYD1_k127_1300171_0 331113.SNE_A18450 5.697e-113 376.0 COG0617@1|root,COG0617@2|Bacteria,2JFVS@204428|Chlamydiae 204428|Chlamydiae H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C DYD1_k127_1310868_4 716544.wcw_0798 2.646e-16 80.0 COG0275@1|root,COG0275@2|Bacteria,2JHHJ@204428|Chlamydiae 204428|Chlamydiae M Putative rRNA methylase - - - - - - - - - - - - rRNA_methylase DYD1_k127_1310868_2 716544.wcw_0791 2.007e-64 234.0 COG0285@1|root,COG0285@2|Bacteria,2JFSY@204428|Chlamydiae 204428|Chlamydiae H Mur ligase middle domain folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M DYD1_k127_1310868_1 35841.BT1A1_1148 5.297e-67 237.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,1ZC55@1386|Bacillus 91061|Bacilli S reductase dkgA - - - - - - - - - - - Aldo_ket_red DYD1_k127_1310868_0 331113.SNE_A13980 4.462e-75 261.0 COG0613@1|root,COG0613@2|Bacteria,2JFUH@204428|Chlamydiae 204428|Chlamydiae S DNA polymerase alpha chain like domain - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP DYD1_k127_1310868_3 765952.PUV_10220 1.097e-29 121.0 COG0812@1|root,COG0812@2|Bacteria,2JFHG@204428|Chlamydiae 204428|Chlamydiae M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C DYD1_k127_1311932_2 411474.COPEUT_01660 5.798e-06 51.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia 186801|Clostridia M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_1311932_1 1444711.CCJF01000005_gene1052 2.688e-14 74.0 COG0472@1|root,COG0472@2|Bacteria,2JFHV@204428|Chlamydiae 204428|Chlamydiae M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 DYD1_k127_1311932_0 665571.STHERM_c08950 8.635e-83 286.0 COG0472@1|root,COG0472@2|Bacteria,2J6QK@203691|Spirochaetes 203691|Spirochaetes M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 DYD1_k127_1356331_2 1444711.CCJF01000005_gene551 6.487e-22 97.0 COG0842@1|root,COG0842@2|Bacteria,2JFXH@204428|Chlamydiae 204428|Chlamydiae V ABC-2 family transporter protein ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD1_k127_1356331_0 1444711.CCJF01000005_gene550 1.574e-194 621.0 COG1131@1|root,COG1131@2|Bacteria,2JFJI@204428|Chlamydiae 204428|Chlamydiae V ABC transporter ybhF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_1356331_1 765952.PUV_01630 9.642e-89 300.0 COG0845@1|root,COG0845@2|Bacteria,2JFET@204428|Chlamydiae 204428|Chlamydiae M Biotin-lipoyl like - - - ko:K01993 - - - - ko00000 - - - HlyD_D23 DYD1_k127_1376804_1 331113.SNE_A05570 1.972e-211 665.0 COG1674@1|root,COG1674@2|Bacteria,2JFN4@204428|Chlamydiae 204428|Chlamydiae D Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity) ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma DYD1_k127_1376804_3 331113.SNE_A05560 3.261e-80 276.0 COG0745@1|root,COG1235@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria 2|Bacteria P May be involved in the transport of PQQ or its precursor to the periplasm elaC - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 DYD1_k127_1376804_2 1444711.CCJF01000004_gene2053 1.182e-97 325.0 COG1235@1|root,COG1235@2|Bacteria,2JFDF@204428|Chlamydiae 204428|Chlamydiae S Metallo-beta-lactamase superfamily yycJ - - - - - - - - - - - Lactamase_B_2 DYD1_k127_1376804_4 716544.wcw_0031 7.493e-78 276.0 COG0204@1|root,COG0204@2|Bacteria,2JHHV@204428|Chlamydiae 204428|Chlamydiae I Transmembrane secretion effector - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - Acyltransferase,MFS_1 DYD1_k127_1376804_0 331113.SNE_A05470 2.118e-272 853.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2JFWU@204428|Chlamydiae 204428|Chlamydiae C 2-oxoisovalerate dehydrogenase, e1 component, alpha and beta subunit CP_0743 - 1.2.4.4 ko:K00167,ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C DYD1_k127_1392512_2 397945.Aave_2787 1.102e-26 119.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - B12-binding,Radical_SAM DYD1_k127_1392512_1 673862.BABL1_400 1.541e-32 138.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - - - - - - - - - - EamA DYD1_k127_1393949_0 331113.SNE_A21420 1.139e-117 395.0 COG0815@1|root,COG0815@2|Bacteria,2JFX7@204428|Chlamydiae 204428|Chlamydiae M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase DYD1_k127_1393949_1 331113.SNE_A21410 1.74e-97 327.0 COG0774@1|root,COG0774@2|Bacteria,2JFHE@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC DYD1_k127_1401554_2 1239962.C943_00462 8.068e-05 48.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes 976|Bacteroidetes S ATPase (AAA superfamily) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 DYD1_k127_1401554_0 1122176.KB903531_gene2847 1.993e-127 415.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IQAX@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD1_k127_1401554_1 485918.Cpin_1398 1.469e-111 370.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK DYD1_k127_1417255_1 331113.SNE_A08770 2.029e-118 386.0 COG1624@1|root,COG1624@2|Bacteria,2JFE0@204428|Chlamydiae 204428|Chlamydiae S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - - - - - - - - - - - DisA_N DYD1_k127_1417255_0 331113.SNE_A08760 4.172e-129 425.0 COG1624@1|root,COG1624@2|Bacteria,2JFIM@204428|Chlamydiae 204428|Chlamydiae S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria CP_0674 - - - - - - - - - - - - DYD1_k127_1417255_2 331113.SNE_A08750 1.213e-76 265.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups rfaG - - ko:K02844 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_143230_1 1405296.Q499_0904 4.751e-67 230.0 COG0208@1|root,COG0208@2|Bacteria,2JFH1@204428|Chlamydiae 204428|Chlamydiae F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm DYD1_k127_143230_0 1123399.AQVE01000001_gene650 0.0 1531.0 COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,4606X@72273|Thiotrichales 72273|Thiotrichales F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN DYD1_k127_1446184_11 765952.PUV_19370 2.846e-32 130.0 COG0496@1|root,COG0496@2|Bacteria,2JFU0@204428|Chlamydiae 204428|Chlamydiae F Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD1_k127_1446184_9 1173028.ANKO01000041_gene3178 2.163e-59 211.0 COG2173@1|root,COG2173@2|Bacteria,1G56H@1117|Cyanobacteria,1HAFJ@1150|Oscillatoriales 1117|Cyanobacteria M Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 DYD1_k127_1446184_3 331113.SNE_A05950 1.55e-111 367.0 COG1284@1|root,COG1284@2|Bacteria,2JFIE@204428|Chlamydiae 204428|Chlamydiae S Uncharacterized protein conserved in bacteria (DUF2179) yqfU - - - - - - - - - - - DUF2179,YitT_membrane DYD1_k127_1446184_7 264201.pc0775 1.408e-87 295.0 COG1611@1|root,COG1611@2|Bacteria,2JFQC@204428|Chlamydiae 204428|Chlamydiae S Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD1_k127_1446184_2 1158604.I591_01367 3.937e-123 400.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,4B0GS@81852|Enterococcaceae 91061|Bacilli H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD1_k127_1446184_0 1444711.CCJF01000005_gene1724 1.746e-235 734.0 COG0439@1|root,COG0439@2|Bacteria,2JFW0@204428|Chlamydiae 204428|Chlamydiae I Biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD1_k127_1446184_10 716544.wcw_0868 2.487e-33 133.0 COG0511@1|root,COG0511@2|Bacteria,2JGBI@204428|Chlamydiae 204428|Chlamydiae I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl DYD1_k127_1446184_8 264201.pc0769 2.061e-73 251.0 COG0231@1|root,COG0231@2|Bacteria,2JFYK@204428|Chlamydiae 204428|Chlamydiae J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp1 - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD1_k127_1446184_1 331113.SNE_A17470 1.242e-152 488.0 COG0391@1|root,COG0391@2|Bacteria 2|Bacteria S phosphotransferase activity, for other substituted phosphate groups ybhK - - - - - - - - - - - UPF0052 DYD1_k127_1446184_4 1444712.BN1013_01751 1.25e-101 336.0 COG0036@1|root,COG0036@2|Bacteria,2JFP2@204428|Chlamydiae 204428|Chlamydiae G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim DYD1_k127_1446184_6 1279017.AQYJ01000025_gene736 3.894e-89 306.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,464I7@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0668 Small-conductance mechanosensitive channel ynaI GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel DYD1_k127_1446184_5 716544.wcw_0863 7.575e-90 310.0 COG4166@1|root,COG4166@2|Bacteria,2JFKE@204428|Chlamydiae 204428|Chlamydiae E transmembrane transport - - - - - - - - - - - - - DYD1_k127_1447634_1 351160.RCIX1480 9.732e-33 138.0 arCOG06926@1|root,arCOG06926@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - DYD1_k127_1447634_0 331113.SNE_A07010 5.653e-136 439.0 COG0039@1|root,COG0039@2|Bacteria,2JFTH@204428|Chlamydiae 204428|Chlamydiae C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N DYD1_k127_1447634_2 716544.wcw_1240 6.119e-24 104.0 COG0372@1|root,COG0372@2|Bacteria,2JFPR@204428|Chlamydiae 204428|Chlamydiae C Citrate synthase, C-terminal domain gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD1_k127_1448143_0 1444711.CCJF01000004_gene2284 2.626e-266 829.0 COG1155@1|root,COG1155@2|Bacteria,2JFIJ@204428|Chlamydiae 204428|Chlamydiae F Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit atpA - 3.6.3.14,3.6.3.15 ko:K02117 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002,ko01000 3.A.2.2,3.A.2.3 - - ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn DYD1_k127_1448143_1 716544.wcw_0604 1.22e-61 221.0 28PGQ@1|root,2ZC7E@2|Bacteria,2JFYT@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF2764) CP_0687 - - - - - - - - - - - DUF2764 DYD1_k127_1448143_2 765952.PUV_23330 3.148e-54 197.0 COG1390@1|root,COG1390@2|Bacteria,2JG7T@204428|Chlamydiae 204428|Chlamydiae C Produces ATP from ADP in the presence of a proton gradient across the membrane atpE - - ko:K02121 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - HrpE DYD1_k127_1452676_4 331113.SNE_A00410 6.305e-07 55.0 298AF@1|root,2ZVFZ@2|Bacteria,2JHFY@204428|Chlamydiae 204428|Chlamydiae M In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan ompA GO:0005575,GO:0005576,GO:0005623,GO:0009986,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044464,GO:0065010 - ko:K03162 - - - - ko00000,ko02000 1.B.2.1 - - Chlam_OMP DYD1_k127_1452676_1 331113.SNE_A01700 7.555e-83 294.0 COG0323@1|root,COG0323@2|Bacteria,2JFM7@204428|Chlamydiae 204428|Chlamydiae L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C DYD1_k127_1452676_2 716544.wcw_1869 7.116e-77 269.0 COG0006@1|root,COG0006@2|Bacteria,2JFYS@204428|Chlamydiae 204428|Chlamydiae E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 DYD1_k127_1452676_0 1437425.CSEC_1736 2.109e-98 337.0 COG5002@1|root,COG5002@2|Bacteria,2JFDA@204428|Chlamydiae 204428|Chlamydiae T PAS domain phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS DYD1_k127_1452676_3 331113.SNE_A01890 1.305e-50 185.0 COG1297@1|root,COG1297@2|Bacteria,2JHFP@204428|Chlamydiae 204428|Chlamydiae S OPT oligopeptide transporter protein - - - - - - - - - - - - OPT DYD1_k127_1482016_0 663610.JQKO01000008_gene199 4.069e-129 434.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR56@28211|Alphaproteobacteria,3N9V6@45404|Beijerinckiaceae 28211|Alphaproteobacteria P haloacid dehalogenase-like hydrolase cadA - - - - - - - - - - - E1-E2_ATPase,Hemerythrin,Hydrolase DYD1_k127_1482016_2 565655.ECBG_02219 0.0005841 49.0 COG0454@1|root,COG0456@2|Bacteria,1VFVQ@1239|Firmicutes,4HK5T@91061|Bacilli,4B332@81852|Enterococcaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_1482016_1 765952.PUV_06700 6.398e-86 292.0 29ZJT@1|root,30MK2@2|Bacteria,2JG2M@204428|Chlamydiae 204428|Chlamydiae - - CP_0080 - - - - - - - - - - - - DYD1_k127_1520417_4 1122207.MUS1_09455 2.014e-05 52.0 COG1986@1|root,COG1986@2|Bacteria,1R60T@1224|Proteobacteria,1RNVT@1236|Gammaproteobacteria,1XPKZ@135619|Oceanospirillales 135619|Oceanospirillales F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - - - - - - - - - - NTPase_I-T DYD1_k127_1520417_0 765952.PUV_17630 5.568e-89 297.0 COG3896@1|root,COG3896@2|Bacteria,2JGFS@204428|Chlamydiae 204428|Chlamydiae V Chloramphenicol phosphotransferase-like protein - - - ko:K18554 - - - - br01600,ko00000,ko01000,ko01504 - - - CPT DYD1_k127_1520417_1 1437425.CSEC_2120 2.403e-51 186.0 COG3708@1|root,COG3708@2|Bacteria,2JGHZ@204428|Chlamydiae 204428|Chlamydiae K Bacterial transcription activator, effector binding domain - - - - - - - - - - - - Cass2 DYD1_k127_1520417_2 935567.JAES01000038_gene998 2.6e-26 118.0 arCOG10178@1|root,2ZAAA@2|Bacteria,1RFIS@1224|Proteobacteria,1SXSR@1236|Gammaproteobacteria,1X8QZ@135614|Xanthomonadales 135614|Xanthomonadales S CAAX protease self-immunity - - - - - - - - - - - - Abi DYD1_k127_1520417_3 267377.MMP0995 1.021e-14 76.0 arCOG04882@1|root,arCOG04882@2157|Archaea,2Y4S5@28890|Euryarchaeota 28890|Euryarchaeota - - - - - - - - - - - - - - - DYD1_k127_1527577_0 1437425.CSEC_2368 3.478e-260 808.0 COG4108@1|root,COG4108@2|Bacteria,2JFKT@204428|Chlamydiae 204428|Chlamydiae J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP - - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,RF3_C DYD1_k127_1527577_2 765952.PUV_21100 5.053e-55 197.0 COG0169@1|root,COG0710@1|root,COG1670@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,COG1670@2|Bacteria,2JFIF@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I,Shikimate_DH,Shikimate_dh_N DYD1_k127_1527577_3 135651.CBN19232 1.881e-06 57.0 COG2940@1|root,KOG1082@2759|Eukaryota,38GXX@33154|Opisthokonta,3BA3A@33208|Metazoa,3D0GH@33213|Bilateria,40EPG@6231|Nematoda,1KX2Z@119089|Chromadorea,410Z5@6236|Rhabditida 33208|Metazoa B SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain EHMT1 GO:0000003,GO:0000122,GO:0000228,GO:0000280,GO:0000785,GO:0000790,GO:0000976,GO:0000977,GO:0001012,GO:0001067,GO:0001708,GO:0002039,GO:0002165,GO:0002682,GO:0002697,GO:0002831,GO:0003006,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005705,GO:0006139,GO:0006259,GO:0006275,GO:0006304,GO:0006305,GO:0006306,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0007049,GO:0007059,GO:0007127,GO:0007129,GO:0007130,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007399,GO:0007444,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007614,GO:0007616,GO:0007626,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008345,GO:0008757,GO:0009267,GO:0009410,GO:0009566,GO:0009605,GO:0009719,GO:0009725,GO:0009755,GO:0009791,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010424,GO:0010468,GO:0010506,GO:0010507,GO:0010556,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010639,GO:0010720,GO:0010769,GO:0010770,GO:0010948,GO:0010975,GO:0010976,GO:0014070,GO:0016043,GO:0016241,GO:0016242,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018026,GO:0018027,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019904,GO:0019953,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023052,GO:0030154,GO:0030182,GO:0030518,GO:0030522,GO:0030534,GO:0030537,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0031344,GO:0031346,GO:0031347,GO:0031399,GO:0031401,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032259,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032776,GO:0032870,GO:0033043,GO:0033044,GO:0033554,GO:0033993,GO:0034641,GO:0034968,GO:0035075,GO:0035076,GO:0035220,GO:0035265,GO:0035295,GO:0035690,GO:0036166,GO:0036211,GO:0036314,GO:0036315,GO:0040007,GO:0042054,GO:0042220,GO:0042221,GO:0042493,GO:0042594,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043279,GO:0043401,GO:0043412,GO:0043414,GO:0043565,GO:0043900,GO:0044030,GO:0044085,GO:0044087,GO:0044088,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0044728,GO:0045132,GO:0045143,GO:0045165,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045786,GO:0045892,GO:0045934,GO:0045995,GO:0046483,GO:0046958,GO:0046959,GO:0046974,GO:0046976,GO:0048148,GO:0048232,GO:0048285,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048589,GO:0048609,GO:0048663,GO:0048665,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050688,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051052,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051276,GO:0051321,GO:0051567,GO:0051569,GO:0051570,GO:0051574,GO:0051704,GO:0051716,GO:0051726,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0060359,GO:0060429,GO:0061647,GO:0061982,GO:0065007,GO:0070013,GO:0070192,GO:0070193,GO:0070316,GO:0070317,GO:0070734,GO:0070742,GO:0070887,GO:0071242,GO:0071310,GO:0071312,GO:0071314,GO:0071383,GO:0071390,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071496,GO:0071704,GO:0071840,GO:0072347,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097305,GO:0097306,GO:0098687,GO:0098813,GO:0120035,GO:0140013,GO:0140096,GO:1900006,GO:1900109,GO:1900111,GO:1901360,GO:1901363,GO:1901564,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902115,GO:1902116,GO:1902275,GO:1902679,GO:1902902,GO:1903046,GO:1903506,GO:1903507,GO:1905269,GO:1990837,GO:1990841,GO:2000026,GO:2000112,GO:2000113,GO:2000785,GO:2001141,GO:2001252 2.1.1.43 ko:K11420 ko00310,ko04211,map00310,map04211 - R03875,R03938,R04866,R04867 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko01000,ko03036 - - - Ank_2,Ank_4,Pre-SET,SET DYD1_k127_1527577_1 314345.SPV1_03293 1.513e-141 459.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria 1224|Proteobacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC - - 3.6.3.6 ko:K01535 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD1_k127_153222_5 1304872.JAGC01000009_gene1079 3.043e-17 85.0 COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MBY3@213115|Desulfovibrionales 28221|Deltaproteobacteria F PFAM Adenylate cyclase - - 4.6.1.1 ko:K05873 ko00230,map00230 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - CYTH DYD1_k127_153222_6 1444712.BN1013_01314 1.737e-06 56.0 COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,2JFTX@204428|Chlamydiae 204428|Chlamydiae CO NifU protein nifU - - ko:K13819 - - - - ko00000 - - - NifU,NifU_N DYD1_k127_153222_2 765952.PUV_06960 2.424e-83 289.0 COG1104@1|root,COG1104@2|Bacteria,2JFKX@204428|Chlamydiae 204428|Chlamydiae E Aminotransferase class-V yfhO_2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 DYD1_k127_153222_0 1444711.CCJF01000005_gene596 1.028e-87 295.0 COG0588@1|root,COG0588@2|Bacteria,2JFCZ@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 DYD1_k127_153222_1 331113.SNE_A03060 8.717e-85 287.0 COG1187@1|root,COG1187@2|Bacteria,2JFFS@204428|Chlamydiae 204428|Chlamydiae J Belongs to the pseudouridine synthase RsuA family yjbC - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_153222_3 264201.pc0098 8.157e-68 237.0 COG1392@1|root,COG1392@2|Bacteria,2JFZT@204428|Chlamydiae 204428|Chlamydiae P Protein of unknown function DUF47 CP_0066 - - ko:K07220 - - - - ko00000 - - - PhoU_div DYD1_k127_153222_4 765952.PUV_06450 1.003e-40 153.0 COG0306@1|root,COG0306@2|Bacteria,2JFPI@204428|Chlamydiae 204428|Chlamydiae P Phosphate CP_0067 - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 DYD1_k127_154188_4 716544.wcw_0099 9.731e-85 286.0 COG0320@1|root,COG0320@2|Bacteria,2JFWH@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM DYD1_k127_154188_1 765952.PUV_08690 1.108e-142 464.0 COG0448@1|root,COG0448@2|Bacteria,2JGPA@204428|Chlamydiae 204428|Chlamydiae H glucose-1-phosphate adenylyltransferase glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD1_k127_154188_3 765952.PUV_08700 9.319e-94 313.0 COG1768@1|root,COG1768@2|Bacteria,2JFIA@204428|Chlamydiae 204428|Chlamydiae S Calcineurin-like phosphoesterase CP_0141 - - ko:K07099 - - - - ko00000 - - - Metallophos DYD1_k127_154188_2 331113.SNE_A06540 7.09e-130 427.0 COG3659@1|root,COG3659@2|Bacteria 2|Bacteria M wide pore channel activity - - - ko:K07267 - - - - ko00000,ko02000 1.B.19.1 - - OprB DYD1_k127_154188_5 765952.PUV_08020 2.96e-68 244.0 28PQ7@1|root,2ZCCC@2|Bacteria,2JFZ6@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_154188_6 765952.PUV_25620 0.0002845 49.0 2EJEX@1|root,33D5W@2|Bacteria,2JGJH@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_154188_0 331113.SNE_A01890 1.566e-164 529.0 COG1297@1|root,COG1297@2|Bacteria,2JHFP@204428|Chlamydiae 204428|Chlamydiae S OPT oligopeptide transporter protein - - - - - - - - - - - - OPT DYD1_k127_1577904_0 331113.SNE_A22200 1.449e-252 799.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2JFW6@204428|Chlamydiae 204428|Chlamydiae L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 DYD1_k127_1577904_3 331113.SNE_A22190 7.547e-90 307.0 COG0616@1|root,COG0616@2|Bacteria,2JFFW@204428|Chlamydiae 204428|Chlamydiae OU Peptidase family S49 sohB - - - - - - - - - - - Peptidase_S49 DYD1_k127_1577904_6 1187848.AJYQ01000022_gene918 1.856e-45 175.0 COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1XUER@135623|Vibrionales 135623|Vibrionales M COG0668 Small-conductance mechanosensitive channel ynaI - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel DYD1_k127_1577904_5 331113.SNE_A22140 1.307e-45 169.0 COG0558@1|root,COG0558@2|Bacteria,2JG6R@204428|Chlamydiae 204428|Chlamydiae I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA_1 - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD1_k127_1577904_4 765952.PUV_03590 1.226e-58 209.0 COG0586@1|root,COG0586@2|Bacteria,2JG5K@204428|Chlamydiae 204428|Chlamydiae S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc DYD1_k127_1577904_1 716544.wcw_1699 2.569e-174 561.0 COG3202@1|root,COG3202@2|Bacteria,2JFQD@204428|Chlamydiae 204428|Chlamydiae P ADP,ATP carrier protein tlcA-C - - ko:K03301 - - - - ko00000 2.A.12 - - TLC DYD1_k127_1577904_2 765952.PUV_24700 2.968e-126 411.0 COG0126@1|root,COG0126@2|Bacteria,2JFK3@204428|Chlamydiae 204428|Chlamydiae F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK DYD1_k127_1582985_3 234831.PSM_A2755 3.64e-24 108.0 COG1280@1|root,COG1280@2|Bacteria,1RD4I@1224|Proteobacteria,1S52N@1236|Gammaproteobacteria,2Q14B@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E threonine efflux protein - - - - - - - - - - - - LysE DYD1_k127_1582985_0 1444711.CCJF01000005_gene801 2.752e-261 816.0 COG1274@1|root,COG1274@2|Bacteria,2JFEW@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N DYD1_k127_1582985_2 1444711.CCJF01000005_gene800 8.694e-201 629.0 COG1077@1|root,COG1077@2|Bacteria,2JFNV@204428|Chlamydiae 204428|Chlamydiae D shape-determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD1_k127_1582985_1 331113.SNE_A19580 7.482e-247 766.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2JFDP@204428|Chlamydiae 204428|Chlamydiae KL SNF2 family CP_1020 - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM DYD1_k127_1584108_4 1444712.BN1013_01493 9.451e-51 183.0 COG0847@1|root,COG0847@2|Bacteria,2JFVY@204428|Chlamydiae 204428|Chlamydiae L DNA polymerase III, epsilon dnaQ_1 - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - QSregVF_b,RNase_T DYD1_k127_1584108_3 28072.Nos7524_5167 2.807e-60 218.0 COG0451@1|root,COG0451@2|Bacteria,1G0RF@1117|Cyanobacteria,1HIFQ@1161|Nostocales 1117|Cyanobacteria GM PFAM NAD dependent epimerase dehydratase family - - - - - - - - - - - - Epimerase,NAD_binding_10 DYD1_k127_1584108_5 765952.PUV_12360 3.47e-09 70.0 2DU2Q@1|root,33NPM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1584108_0 331113.SNE_A08020 4.446e-255 801.0 COG1132@1|root,COG1132@2|Bacteria,2JFRB@204428|Chlamydiae 204428|Chlamydiae V Lipid A export ATP-binding permease protein msbA - - ko:K02021,ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_1584108_1 331113.SNE_A08010 5.002e-138 446.0 COG0825@1|root,COG0825@2|Bacteria,2JFES@204428|Chlamydiae 204428|Chlamydiae I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA DYD1_k127_1584108_2 765952.PUV_13200 1.209e-96 321.0 COG1376@1|root,COG1376@2|Bacteria,2JFN1@204428|Chlamydiae 204428|Chlamydiae S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD DYD1_k127_1601267_0 765952.PUV_21180 1.349e-139 452.0 COG0474@1|root,COG0474@2|Bacteria,2JFV3@204428|Chlamydiae 204428|Chlamydiae P Cation transporter/ATPase, N-terminus - - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD1_k127_1601267_1 765952.PUV_21180 3.51e-11 68.0 COG0474@1|root,COG0474@2|Bacteria,2JFV3@204428|Chlamydiae 204428|Chlamydiae P Cation transporter/ATPase, N-terminus - - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD1_k127_164437_1 1168289.AJKI01000051_gene853 1.099e-117 385.0 COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,2FQ1D@200643|Bacteroidia,3XKD3@558415|Marinilabiliaceae 976|Bacteroidetes LV TaqI-like C-terminal specificity domain - - - - - - - - - - - - Eco57I,N6_Mtase,TaqI_C DYD1_k127_164437_6 293826.Amet_3370 6.021e-05 50.0 COG3620@1|root,COG3620@2|Bacteria,1VH02@1239|Firmicutes,24RIF@186801|Clostridia,36VX9@31979|Clostridiaceae 186801|Clostridia K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 DYD1_k127_164437_5 478741.JAFS01000002_gene198 7.625e-13 72.0 COG3549@1|root,COG3549@2|Bacteria 2|Bacteria S RelE-like toxin of type II toxin-antitoxin system HigB - - - - - - - - - - - - HigB-like_toxin DYD1_k127_164437_0 32057.KB217478_gene4768 1.094e-128 421.0 COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,1G7WR@1117|Cyanobacteria,1HNZ0@1161|Nostocales 1117|Cyanobacteria K Helix-turn-helix XRE-family like proteins - - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3,Peptidase_M78 DYD1_k127_164437_2 1192868.CAIU01000023_gene3291 1.926e-27 117.0 COG3600@1|root,COG3600@2|Bacteria,1N78U@1224|Proteobacteria,2UGBJ@28211|Alphaproteobacteria,43QMQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF4065) gepA - - - - - - - - - - - DUF4065 DYD1_k127_1675093_6 716544.wcw_0142 3.149e-12 67.0 2AKRI@1|root,31BID@2|Bacteria,2JGD9@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1675093_4 331113.SNE_A11780 5.724e-30 125.0 2AUKY@1|root,31K9Q@2|Bacteria 2|Bacteria S Lipid A 3-O-deacylase (PagL) - - - - - - - - - - - - PagL DYD1_k127_1675093_2 331113.SNE_A11790 1.216e-93 317.0 COG0429@1|root,COG0429@2|Bacteria,2JH18@204428|Chlamydiae 204428|Chlamydiae S Alpha/beta hydrolase family - - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 DYD1_k127_1675093_0 331113.SNE_A13060 3.309e-159 515.0 COG3202@1|root,COG3202@2|Bacteria,2JGM0@204428|Chlamydiae 204428|Chlamydiae P TLC ATP/ADP transporter tlcA-B - - - - - - - - - - - TLC DYD1_k127_1675093_5 1437425.CSEC_2125 1.367e-29 124.0 COG0537@1|root,COG0537@2|Bacteria,2JH6U@204428|Chlamydiae 204428|Chlamydiae FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT DYD1_k127_1675093_1 331113.SNE_A08280 5.963e-111 368.0 COG1398@1|root,COG1398@2|Bacteria,2JFP0@204428|Chlamydiae 204428|Chlamydiae I Fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase DYD1_k127_1675093_3 202954.BBNK01000004_gene1907 1.751e-40 154.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,3NN4E@468|Moraxellaceae 1236|Gammaproteobacteria O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR DYD1_k127_1681876_0 272560.BPSS0422 2.815e-116 381.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1K1NS@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the DegT DnrJ EryC1 family - - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - Acetyltransf_3,CBS,DegT_DnrJ_EryC1 DYD1_k127_1681876_2 1121382.JQKG01000010_gene4638 7.07e-91 306.0 COG3959@1|root,COG3959@2|Bacteria,1WMNT@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD1_k127_1681876_1 1303518.CCALI_01668 6.778e-98 329.0 COG3958@1|root,COG3958@2|Bacteria 2|Bacteria G transketolase activity tktC - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_1681876_3 419665.Maeo_0390 5.048e-23 110.0 COG0463@1|root,arCOG01381@2157|Archaea,2Y22T@28890|Euryarchaeota,23RBM@183939|Methanococci 183939|Methanococci M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_1685152_8 1268622.AVS7_03745 1.158e-05 48.0 2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria,2VXU8@28216|Betaproteobacteria,4AFZA@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3096) - - - - - - - - - - - - DUF3096 DYD1_k127_1685152_4 1232410.KI421428_gene1056 3.167e-83 282.0 COG1235@1|root,COG1235@2|Bacteria,1RIT2@1224|Proteobacteria,42SFE@68525|delta/epsilon subdivisions,2WPTA@28221|Deltaproteobacteria,43UMZ@69541|Desulfuromonadales 28221|Deltaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B_2 DYD1_k127_1685152_7 765952.PUV_21010 1.986e-15 78.0 2ENCP@1|root,33G06@2|Bacteria,2JHC7@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1685152_6 765952.PUV_21010 9.558e-22 96.0 2ENCP@1|root,33G06@2|Bacteria,2JHC7@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1685152_3 765952.PUV_00570 4.922e-90 304.0 COG0109@1|root,COG0109@2|Bacteria,2JFWP@204428|Chlamydiae 204428|Chlamydiae H Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA DYD1_k127_1685152_1 331113.SNE_A16230 1.426e-128 422.0 COG0513@1|root,COG0513@2|Bacteria,2JFPJ@204428|Chlamydiae 204428|Chlamydiae L Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C DYD1_k127_1685152_0 331113.SNE_A17010 5.175e-206 672.0 COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,2JFJE@204428|Chlamydiae 204428|Chlamydiae IQ AMP-binding enzyme aas - 6.2.1.20 ko:K01909 ko00071,map00071 - R01406 RC00014,RC00039 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase,PP-binding DYD1_k127_1685152_2 1382359.JIAL01000001_gene2838 5.956e-92 309.0 KOG1573@1|root,2Z822@2|Bacteria,3Y3AN@57723|Acidobacteria,2JKNN@204432|Acidobacteriia 204432|Acidobacteriia S Myo-inositol oxygenase - - 1.13.99.1 ko:K00469 ko00053,ko00562,map00053,map00562 - R01184 RC00465 ko00000,ko00001,ko01000 - - - MIOX DYD1_k127_1685691_1 331113.SNE_A23010 8.682e-126 410.0 COG0113@1|root,COG0113@2|Bacteria,2JFHF@204428|Chlamydiae 204428|Chlamydiae H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD DYD1_k127_1685691_4 264201.pc1119 4.574e-43 168.0 COG0463@1|root,COG0463@2|Bacteria,2JG4U@204428|Chlamydiae 204428|Chlamydiae M Glycosyltransferase family 92 - - - - - - - - - - - - Glyco_transf_92 DYD1_k127_1685691_3 1306947.ARQD01000001_gene899 2.222e-68 245.0 COG0457@1|root,COG0457@2|Bacteria 1306947.ARQD01000001_gene899|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_1685691_5 331113.SNE_A23640 5.281e-08 63.0 2EQNW@1|root,347ZJ@2|Bacteria,2JHB0@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1685691_0 331113.SNE_A22990 7.805e-246 769.0 COG1351@1|root,COG1351@2|Bacteria,2JFK7@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant CP_1126 - - - - - - - - - - - Thy1 DYD1_k127_1685691_2 331113.SNE_A22980 5.974e-82 282.0 COG0814@1|root,COG0814@2|Bacteria,2JFFY@204428|Chlamydiae 204428|Chlamydiae E Tryptophan/tyrosine permease family tyrP_1 - - ko:K03834 - - - - ko00000,ko02000 2.A.42.1.1 - - Trp_Tyr_perm DYD1_k127_1727394_1 1297581.H919_06706 1.359e-123 406.0 COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,4HBXU@91061|Bacilli 91061|Bacilli GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase DYD1_k127_1727394_3 331113.SNE_A16460 2.075e-61 219.0 292EW@1|root,2ZPZ5@2|Bacteria,2JG20@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1727394_0 765952.PUV_17070 3.359e-182 580.0 COG1875@1|root,COG1875@2|Bacteria,2JFG7@204428|Chlamydiae 204428|Chlamydiae T phosphate starvation-inducible protein PhoH phoH - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH DYD1_k127_1727394_5 1123257.AUFV01000001_gene1855 4.43e-16 83.0 COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,1SPRS@1236|Gammaproteobacteria,1XAQU@135614|Xanthomonadales 135614|Xanthomonadales B SWI complex, BAF60b domains - - - - - - - - - - - - SWIB DYD1_k127_1727394_7 1321815.HMPREF9193_00022 4.329e-06 51.0 COG3774@1|root,COG3774@2|Bacteria,2J5VN@203691|Spirochaetes 203691|Spirochaetes M Glycosyltransferase - - - - - - - - - - - - Gly_transf_sug DYD1_k127_1727394_4 653948.CCA15666 2.049e-30 128.0 COG3774@1|root,2S4FC@2759|Eukaryota 2759|Eukaryota M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Gly_transf_sug DYD1_k127_1727394_2 1297581.H919_06091 9.747e-100 342.0 COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,4HAQN@91061|Bacilli,21WIX@150247|Anoxybacillus 91061|Bacilli M Glycosyl transferase family group 2 icaA - - - - - - - - - - - Chitin_synth_2,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 DYD1_k127_1727394_8 65393.PCC7424_1391 0.0002096 46.0 COG1413@1|root,COG1413@2|Bacteria,1G528@1117|Cyanobacteria,3KHZP@43988|Cyanothece 1117|Cyanobacteria C PBS lyase HEAT domain protein repeat-containing protein - - - - - - - - - - - - HEAT_2 DYD1_k127_1771409_2 1444712.BN1013_01711 2.908e-36 141.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding CP_0464 - - ko:K01999,ko:K07001 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - HTH_Crp_2,cNMP_binding DYD1_k127_1771409_0 1444712.BN1013_01712 2.111e-175 584.0 COG3202@1|root,COG3202@2|Bacteria 2|Bacteria C ATP:ADP antiporter activity CP_0465 - - - - - - - - - - - HEAT_2,TLC,cNMP_binding DYD1_k127_1771409_3 1158318.ATXC01000001_gene672 3.066e-35 145.0 COG0345@1|root,COG0345@2|Bacteria,2G42Q@200783|Aquificae 200783|Aquificae E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer DYD1_k127_1771409_1 1444711.CCJF01000005_gene1342 3.905e-149 477.0 COG0492@1|root,COG0492@2|Bacteria,2JFQH@204428|Chlamydiae 204428|Chlamydiae C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_1771409_4 1444711.CCJF01000005_gene1343 1.226e-09 64.0 2CP5R@1|root,33T3X@2|Bacteria,2JGYC@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1778970_1 331113.SNE_A20160 2.075e-22 102.0 2EE6N@1|root,33817@2|Bacteria,2JGGF@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1778970_2 69319.XP_008556026.1 3.243e-07 62.0 KOG1987@1|root,KOG1987@2759|Eukaryota,38DSA@33154|Opisthokonta,3BFGK@33208|Metazoa,3CR5U@33213|Bilateria,41UVD@6656|Arthropoda,3SKER@50557|Insecta,46GG0@7399|Hymenoptera 33208|Metazoa D Speckle-type POZ protein - - - ko:K10523 ko04340,ko04341,map04340,map04341 M00384 - - ko00000,ko00001,ko00002,ko04121 - - - BTB DYD1_k127_1778970_0 765952.PUV_17750 1.994e-57 203.0 COG1610@1|root,COG1610@2|Bacteria,2JH0E@204428|Chlamydiae 204428|Chlamydiae S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY DYD1_k127_1824665_1 716544.wcw_0575 1.827e-48 180.0 COG1413@1|root,COG1413@2|Bacteria,2JFPT@204428|Chlamydiae 204428|Chlamydiae C lyase activity - - - - - - - - - - - - HEAT_2 DYD1_k127_1824665_0 716544.wcw_0579 1.35e-123 408.0 COG0006@1|root,COG0006@2|Bacteria,2JFCK@204428|Chlamydiae 204428|Chlamydiae E Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 DYD1_k127_1824665_2 264201.pc0592 3.617e-33 132.0 COG2166@1|root,COG2166@2|Bacteria,2JG8A@204428|Chlamydiae 204428|Chlamydiae S Fe-S metabolism associated domain sufE - - ko:K02426 - - - - ko00000 - - - SufE DYD1_k127_1824665_3 331113.SNE_A15200 7.902e-19 87.0 COG0361@1|root,COG0361@2|Bacteria,2JG9T@204428|Chlamydiae 204428|Chlamydiae J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a DYD1_k127_1825756_0 331113.SNE_A09530 1.461e-122 397.0 COG0364@1|root,COG0364@2|Bacteria,2JFEN@204428|Chlamydiae 204428|Chlamydiae G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N DYD1_k127_1825756_1 331113.SNE_A09520 1.973e-80 280.0 COG3429@1|root,COG3429@2|Bacteria,2JG6P@204428|Chlamydiae 204428|Chlamydiae G Glucose-6-phosphate dehydrogenase subunit - - - - - - - - - - - - OpcA_G6PD_assem DYD1_k127_1825756_2 331113.SNE_A09510 1.316e-67 236.0 COG0363@1|root,COG0363@2|Bacteria,2JFZ0@204428|Chlamydiae 204428|Chlamydiae G 6-phosphogluconolactonase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso DYD1_k127_1887081_3 331113.SNE_A01140 2.807e-06 51.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity yabS - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA,VWA_2 DYD1_k127_1887081_1 1437425.CSEC_1667 8.808e-36 142.0 COG0742@1|root,COG0742@2|Bacteria,2JG8V@204428|Chlamydiae 204428|Chlamydiae L Conserved hypothetical protein 95 yhhF - - - - - - - - - - - Cons_hypoth95 DYD1_k127_1887081_2 1122218.KB893653_gene1180 4.305e-35 139.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2U74H@28211|Alphaproteobacteria,1JRY3@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD1_k127_1887081_0 765952.PUV_25720 6.371e-162 541.0 COG2849@1|root,COG2849@2|Bacteria,2JGQS@204428|Chlamydiae 204428|Chlamydiae S MORN repeat variant - - - - - - - - - - - - MORN_2 DYD1_k127_1887081_4 157072.XP_008862557.1 5.226e-05 54.0 2BZVS@1|root,2STBM@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - DYD1_k127_1901704_1 331113.SNE_A07910 1.718e-64 228.0 COG0120@1|root,COG0120@2|Bacteria,2JG19@204428|Chlamydiae 204428|Chlamydiae G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A DYD1_k127_1901704_0 161934.XP_010683748.1 1.11e-137 449.0 COG0162@1|root,KOG2623@2759|Eukaryota,37RBV@33090|Viridiplantae,3G73P@35493|Streptophyta 35493|Streptophyta J Tyrosyl-tRNA synthetase - GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061458,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b DYD1_k127_1901704_2 716544.wcw_1333 6.433e-42 157.0 COG0776@1|root,COG0776@2|Bacteria,2JG67@204428|Chlamydiae 204428|Chlamydiae L Belongs to the bacterial histone-like protein family ihfA - - - - - - - - - - - Bac_DNA_binding DYD1_k127_1901704_4 765952.PUV_13190 6.431e-07 60.0 2CHFT@1|root,341UR@2|Bacteria,2JH4I@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1911041_0 765952.PUV_21030 1.752e-144 472.0 COG0841@1|root,COG0841@2|Bacteria,2JFQA@204428|Chlamydiae 204428|Chlamydiae V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family acrB - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD1_k127_1911041_1 765952.PUV_21020 1.158e-27 117.0 COG1538@1|root,COG1538@2|Bacteria,2JFMS@204428|Chlamydiae 204428|Chlamydiae MU Outer membrane efflux protein - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - OEP DYD1_k127_1986680_7 1034345.CAEM01000036_gene574 2.371e-25 109.0 COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CV84@84998|Coriobacteriia 84998|Coriobacteriia F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Acyltransferase,Cytidylate_kin DYD1_k127_1986680_6 331113.SNE_A21750 1.901e-58 213.0 COG4589@1|root,COG4589@2|Bacteria,2JHI7@204428|Chlamydiae 204428|Chlamydiae S Cytidylyltransferase family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 DYD1_k127_1986680_4 331113.SNE_A21760 6.766e-85 288.0 COG0020@1|root,COG0020@2|Bacteria,2JFZ2@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD1_k127_1986680_2 716544.wcw_0315 1.116e-147 481.0 COG0104@1|root,COG0104@2|Bacteria,2JFRZ@204428|Chlamydiae 204428|Chlamydiae F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt DYD1_k127_1986680_0 331113.SNE_A21850 0.0 1356.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2JFRC@204428|Chlamydiae 204428|Chlamydiae U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4 - - SecD_SecF DYD1_k127_1986680_5 1034943.BN1094_03646 3.783e-80 292.0 COG2114@1|root,COG2114@2|Bacteria,1RBTC@1224|Proteobacteria,1S09F@1236|Gammaproteobacteria,1JE71@118969|Legionellales 118969|Legionellales T Cache domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,dCache_1 DYD1_k127_1986680_1 331113.SNE_A21860 1.903e-236 743.0 COG0608@1|root,COG0608@2|Bacteria,2JFK9@204428|Chlamydiae 204428|Chlamydiae L exonuclease recJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD1_k127_1986680_3 331113.SNE_A03430 7.097e-90 317.0 COG2831@1|root,COG2831@2|Bacteria 2|Bacteria U hemolysin activation secretion protein - - - - - - - - - - - - POTRA,POTRA_2,ShlB DYD1_k127_1986919_0 1444712.BN1013_00834 1.35e-124 407.0 COG2801@1|root,COG2801@2|Bacteria,2JHEV@204428|Chlamydiae 204428|Chlamydiae L Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve DYD1_k127_1986919_1 1444712.BN1013_00835 5.248e-35 136.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 DYD1_k127_1986919_2 192952.MM_0250 7.302e-05 46.0 COG3436@1|root,arCOG04792@2157|Archaea,2XTVF@28890|Euryarchaeota 28890|Euryarchaeota L COG3436 Transposase and inactivated derivatives - - - ko:K07484 - - - - ko00000 - - - DDE_Tnp_IS66,SlyX,zf-IS66 DYD1_k127_1991799_7 331113.SNE_A03570 3.644e-17 83.0 COG0597@1|root,COG0597@2|Bacteria,2JG71@204428|Chlamydiae 204428|Chlamydiae MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 DYD1_k127_1991799_5 1444711.CCJF01000005_gene146 6.592e-53 194.0 2B2S9@1|root,31VCJ@2|Bacteria,2JG87@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_1991799_6 331113.SNE_A03590 1.439e-40 158.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2JFK1@204428|Chlamydiae 204428|Chlamydiae S Probable molybdopterin binding domain cinA - 3.5.1.42 ko:K03742 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth DYD1_k127_1991799_1 1444711.CCJF01000005_gene137 6.615e-101 336.0 COG1092@1|root,COG1092@2|Bacteria,2JFQ3@204428|Chlamydiae 204428|Chlamydiae H S-adenosylmethionine-dependent methyltransferase CP_0221 - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM DYD1_k127_1991799_0 765952.PUV_26920 4.839e-109 359.0 COG0566@1|root,COG0566@2|Bacteria,2JFQK@204428|Chlamydiae 204428|Chlamydiae J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU_1 - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind DYD1_k127_1991799_4 331113.SNE_A03620 3.43e-59 212.0 COG0564@1|root,COG0564@2|Bacteria,2JG1U@204428|Chlamydiae 204428|Chlamydiae J RNA pseudouridylate synthase - - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 DYD1_k127_1991799_8 5808.XP_002141058.1 3.897e-08 62.0 KOG1674@1|root,KOG1674@2759|Eukaryota,3YBIN@5794|Apicomplexa,3YMZB@5796|Coccidia 5794|Apicomplexa D Cyclin - - - - - - - - - - - - Cyclin DYD1_k127_1991799_2 755178.Cyan10605_0019 2.283e-91 311.0 COG0136@1|root,COG0136@2|Bacteria,1G0E6@1117|Cyanobacteria 1117|Cyanobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD1_k127_1991799_3 1444711.CCJF01000005_gene130 3.158e-66 231.0 COG0279@1|root,COG0279@2|Bacteria,2JFXT@204428|Chlamydiae 204428|Chlamydiae G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 DYD1_k127_1994251_1 908340.HMPREF9406_1026 8.062e-06 55.0 2E9NX@1|root,333VC@2|Bacteria,1VFKV@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - DYD1_k127_1994251_0 1033806.HTIA_1260 1.403e-50 190.0 COG3568@1|root,arCOG08107@2157|Archaea,2XWUM@28890|Euryarchaeota,23VI9@183963|Halobacteria 183963|Halobacteria L COG3568 Metal-dependent hydrolase - - - - - - - - - - - - Exo_endo_phos DYD1_k127_1996277_2 331113.SNE_A15960 1.469e-104 353.0 28N6X@1|root,2ZBBQ@2|Bacteria,2JFR2@204428|Chlamydiae 204428|Chlamydiae S Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_1996277_6 765952.PUV_18030 0.0002688 44.0 COG1961@1|root,COG1961@2|Bacteria,2JGRW@204428|Chlamydiae 204428|Chlamydiae L Resolvase, N terminal domain - - - - - - - - - - - - Resolvase,Zn_ribbon_recom DYD1_k127_1996277_5 1121447.JONL01000001_gene735 6.44e-05 49.0 2EG8N@1|root,33A0G@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1996277_4 589865.DaAHT2_1054 2.806e-08 58.0 COG3012@1|root,COG3012@2|Bacteria,1QZ4P@1224|Proteobacteria 1224|Proteobacteria C Pfam SEC-C motif - - - - - - - - - - - - SEC-C DYD1_k127_1996277_1 1444711.CCJF01000005_gene1714 2.588e-108 355.0 COG0037@1|root,COG0037@2|Bacteria,2JFSJ@204428|Chlamydiae 204428|Chlamydiae H Belongs to the TtcA family ttcA - - - - - - - - - - - ATP_bind_3 DYD1_k127_1996277_0 331113.SNE_A06000 3.994e-154 501.0 COG0591@1|root,COG0591@2|Bacteria,2JFMA@204428|Chlamydiae 204428|Chlamydiae E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF DYD1_k127_1996277_3 765952.PUV_19370 1.991e-46 171.0 COG0496@1|root,COG0496@2|Bacteria,2JFU0@204428|Chlamydiae 204428|Chlamydiae F Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD1_k127_2049989_4 331635.G5S_0889 6.463e-09 58.0 COG0621@1|root,COG0621@2|Bacteria,2JFRX@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,UPF0004 DYD1_k127_2049989_0 331113.SNE_A11630 2.191e-111 367.0 COG0601@1|root,COG0601@2|Bacteria,2JFFJ@204428|Chlamydiae 204428|Chlamydiae P permease protein oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 DYD1_k127_2049989_1 331113.SNE_A11620 1.504e-104 346.0 COG1173@1|root,COG1173@2|Bacteria,2JFP9@204428|Chlamydiae 204428|Chlamydiae P ABC transporter (permease) oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N DYD1_k127_2049989_2 1121346.KB899816_gene3300 3.225e-91 309.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,274NZ@186822|Paenibacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD2 - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_2049989_3 717605.Theco_0045 1.377e-67 237.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,26QEH@186822|Paenibacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_2054055_0 1444711.CCJF01000005_gene1323 5.814e-108 354.0 COG0508@1|root,COG0508@2|Bacteria,2JFHR@204428|Chlamydiae 204428|Chlamydiae C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_2054055_1 331113.SNE_A00770 5.823e-20 98.0 2EQNW@1|root,33I8U@2|Bacteria,2JGJ8@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2054055_2 1437425.CSEC_1422 1.394e-13 79.0 2EQNW@1|root,33I8U@2|Bacteria,2JGJ8@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2054055_3 1437425.CSEC_1422 2.581e-12 72.0 2EQNW@1|root,33I8U@2|Bacteria,2JGJ8@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2062690_0 1415778.JQMM01000001_gene260 7.752e-179 571.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C DYD1_k127_2062690_2 4792.ETI31134 1.224e-21 104.0 KOG1947@1|root,KOG1947@2759|Eukaryota,3QCMI@4776|Peronosporales 4776|Peronosporales S Leucine-rich repeat - CC (cysteine-containing) subfamily - - - ko:K10279,ko:K10280 - - - - ko00000,ko04121 - - - LRR_6 DYD1_k127_2062690_1 765952.PUV_03460 6.779e-139 479.0 2C4IS@1|root,2Z81U@2|Bacteria 2|Bacteria S Lantibiotic dehydratase, C terminus spaB - - ko:K20483 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - Lant_dehydr_C,Lant_dehydr_N DYD1_k127_2062690_3 1121957.ATVL01000009_gene900 4.221e-18 86.0 COG1028@1|root,COG1028@2|Bacteria,4NIH6@976|Bacteroidetes,47MQG@768503|Cytophagia 976|Bacteroidetes IQ PFAM Short-chain dehydrogenase reductase SDR - - 1.1.1.69 ko:K00046 - - - - ko00000,ko01000 - - - adh_short_C2 DYD1_k127_2063175_0 331113.SNE_A17070 7.128e-151 482.0 COG0304@1|root,COG0304@2|Bacteria,2JFJJ@204428|Chlamydiae 204428|Chlamydiae I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_2063175_2 716544.wcw_1375 1.89e-38 147.0 COG0799@1|root,COG0799@2|Bacteria,2JGA1@204428|Chlamydiae 204428|Chlamydiae J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD1_k127_2063175_3 331113.SNE_A17090 5.209e-37 146.0 COG1057@1|root,COG1057@2|Bacteria,2JG9K@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD1_k127_2063175_4 1437425.CSEC_0744 9.578e-24 115.0 COG3968@1|root,COG3968@2|Bacteria,2JFSK@204428|Chlamydiae 204428|Chlamydiae S Glutamine synthetase, catalytic domain glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C DYD1_k127_2063175_1 1444711.CCJF01000005_gene1066 8.672e-120 402.0 COG1196@1|root,COG1196@2|Bacteria,2JFK2@204428|Chlamydiae 204428|Chlamydiae D nuclear chromosome segregation CP_0954 - - - - - - - - - - - - DYD1_k127_2067659_1 1047013.AQSP01000103_gene1154 1.324e-39 155.0 COG5340@1|root,COG5340@2|Bacteria 2|Bacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - AbiEi_4 DYD1_k127_2067659_0 1047013.AQSP01000103_gene1153 1.89e-83 286.0 COG2253@1|root,COG2253@2|Bacteria 2|Bacteria V Psort location Cytoplasmic, score - - - - - - - - - - - - AbiEii DYD1_k127_2067659_2 203124.Tery_1485 7.902e-37 147.0 COG4122@1|root,COG4122@2|Bacteria,1G8BJ@1117|Cyanobacteria 1117|Cyanobacteria S O-methyltransferase activity - - - - - - - - - - - - Methyltransf_24 DYD1_k127_2074301_0 716544.wcw_0034 7.722e-81 287.0 COG0507@1|root,COG0507@2|Bacteria,2JFVA@204428|Chlamydiae 204428|Chlamydiae L ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member recD1 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,UvrD_C_2 DYD1_k127_2074301_1 331113.SNE_A04420 6.276e-20 92.0 COG2271@1|root,COG2271@2|Bacteria 2|Bacteria G transmembrane transporter activity - - - - - - - - - - - - MFS_1 DYD1_k127_209852_2 316058.RPB_3809 4.639e-39 146.0 COG0500@1|root,COG2226@2|Bacteria,1QSZ6@1224|Proteobacteria,2UMB9@28211|Alphaproteobacteria,3K60Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11 DYD1_k127_209852_0 1121033.AUCF01000009_gene1169 2.818e-118 389.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,2JR3C@204441|Rhodospirillales 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD1_k127_209852_1 697282.Mettu_1299 1.9e-101 344.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1R7DJ@1224|Proteobacteria,1SZ00@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB DYD1_k127_2144688_0 765952.PUV_24140 3.744e-10 61.0 COG1480@1|root,COG1480@2|Bacteria,2JFF5@204428|Chlamydiae 204428|Chlamydiae S Metal dependent phosphohydrolases with conserved 'HD' motif. yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD DYD1_k127_2144688_1 877455.Metbo_1416 3.578e-06 49.0 COG0225@1|root,arCOG02816@2157|Archaea,2XWKA@28890|Euryarchaeota,23P6F@183925|Methanobacteria 183925|Methanobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR DYD1_k127_2151698_0 331113.SNE_A11000 3.289e-15 88.0 COG1357@1|root,COG2071@1|root,COG1357@2|Bacteria,COG2071@2|Bacteria,2JHGT@204428|Chlamydiae 204428|Chlamydiae S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 DYD1_k127_2159783_7 1437425.CSEC_2349 6.81e-56 201.0 COG0604@1|root,COG0604@2|Bacteria,2JFI9@204428|Chlamydiae 204428|Chlamydiae C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 DYD1_k127_2159783_6 765952.PUV_15690 1.671e-73 257.0 COG1216@1|root,COG1216@2|Bacteria,2JGWW@204428|Chlamydiae 204428|Chlamydiae S Glycosyl transferase, family 2 - - - - - - - - - - - - - DYD1_k127_2159783_8 55529.EKX43421 1.393e-40 161.0 2EUZ0@1|root,2SX1J@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - DYD1_k127_2159783_10 331113.SNE_A23270 2.983e-22 102.0 COG0212@1|root,COG0212@2|Bacteria,2JGFC@204428|Chlamydiae 204428|Chlamydiae H 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig DYD1_k127_2159783_4 264201.pc1991 2.225e-90 312.0 COG2849@1|root,COG2849@2|Bacteria,2JFW2@204428|Chlamydiae 204428|Chlamydiae S MORN repeat variant CP_1108 - - - - - - - - - - - MORN_2 DYD1_k127_2159783_15 765952.PUV_00210 2.405e-05 54.0 28PTN@1|root,2ZCEV@2|Bacteria,2JFZY@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2159783_9 765952.PUV_00220 1.313e-25 122.0 COG4972@1|root,COG4972@2|Bacteria,2JFIK@204428|Chlamydiae 204428|Chlamydiae NU Pilus assembly protein - - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 DYD1_k127_2159783_11 331113.SNE_A23310 1.46e-20 93.0 COG0762@1|root,COG0762@2|Bacteria,2JGD3@204428|Chlamydiae 204428|Chlamydiae S YGGT family ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT DYD1_k127_2159783_2 716544.wcw_1972 1.343e-137 445.0 COG0042@1|root,COG0042@2|Bacteria,2JFI0@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus DYD1_k127_2159783_13 639282.DEFDS_0637 1.204e-16 82.0 COG1254@1|root,COG1254@2|Bacteria,2GG1J@200930|Deferribacteres 200930|Deferribacteres C Acylphosphatase - - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase DYD1_k127_2159783_14 331113.SNE_A23150 1.633e-16 85.0 COG3688@1|root,COG3688@2|Bacteria,2JGDZ@204428|Chlamydiae 204428|Chlamydiae S YacP-like NYN domain - - - ko:K06962 - - - - ko00000 - - - NYN_YacP DYD1_k127_2159783_5 1444712.BN1013_00412 6.291e-75 257.0 COG0127@1|root,COG0127@2|Bacteria,2JG0G@204428|Chlamydiae 204428|Chlamydiae F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions yggV - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like DYD1_k127_2159783_0 331113.SNE_A23130 5.385e-259 818.0 COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2JFR7@204428|Chlamydiae 204428|Chlamydiae K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - - - - - - - - - - GreA_GreB,GreA_GreB_N DYD1_k127_2159783_1 331113.SNE_A23030 9.501e-233 740.0 COG0671@1|root,COG0671@2|Bacteria,2JFG9@204428|Chlamydiae 204428|Chlamydiae I Exopolysaccharide biosynthesis protein YbjH - - - - - - - - - - - - YjbH DYD1_k127_2159783_3 697282.Mettu_3431 1.272e-109 364.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XEHC@135618|Methylococcales 135618|Methylococcales P haloacid dehalogenase-like hydrolase - - - - - - - - - - - - E1-E2_ATPase,Hydrolase DYD1_k127_2219553_1 1437425.CSEC_2019 1.214e-87 297.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2JGR0@204428|Chlamydiae 204428|Chlamydiae H Pyruvate phosphate dikinase, PEP/pyruvate binding domain ppsA - 2.7.9.1,2.7.9.2 ko:K01006,ko:K01007 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173,M00374 R00199,R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N DYD1_k127_2219553_3 1437425.CSEC_2221 1.652e-58 209.0 COG0125@1|root,COG0125@2|Bacteria,2JG2V@204428|Chlamydiae 204428|Chlamydiae F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin DYD1_k127_2219553_4 264201.pc1072 6.325e-50 190.0 COG0470@1|root,COG0470@2|Bacteria,2JGB3@204428|Chlamydiae 204428|Chlamydiae L DNA polymerase III holB - 2.7.7.7 ko:K02341,ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 DYD1_k127_2219553_5 161934.XP_010690834.1 0.0003426 52.0 2BZER@1|root,2QPQI@2759|Eukaryota,37MJF@33090|Viridiplantae,3GBM8@35493|Streptophyta 35493|Streptophyta O protein binding zinc ion binding - - - - - - - - - - - - zf-RING_2 DYD1_k127_2219553_2 331113.SNE_A08870 1.196e-85 291.0 COG0061@1|root,COG0061@2|Bacteria,2JFSA@204428|Chlamydiae 204428|Chlamydiae F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP ppnK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase DYD1_k127_2219553_0 1444711.CCJF01000005_gene1379 2.001e-237 745.0 COG1154@1|root,COG1154@2|Bacteria,2JFSC@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C DYD1_k127_2228077_0 331113.SNE_A01910 9.688e-73 263.0 28PQ7@1|root,2ZCCC@2|Bacteria,2JFZ6@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2235642_0 1449063.JMLS01000001_gene4412 1.774e-44 178.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4ISP7@91061|Bacilli,26QDV@186822|Paenibacillaceae 91061|Bacilli EGP Major facilitator superfamily yhcA1 - - - - - - - - - - - MFS_1 DYD1_k127_2235642_2 2880.D7FSQ5 4.664e-37 159.0 COG0076@1|root,KOG1383@2759|Eukaryota 2759|Eukaryota E sphinganine-1-phosphate aldolase activity SGPL1 GO:0000003,GO:0001501,GO:0001553,GO:0001568,GO:0001570,GO:0001655,GO:0001667,GO:0001822,GO:0001944,GO:0002376,GO:0002520,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005938,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006672,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006915,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007283,GO:0007525,GO:0007527,GO:0007548,GO:0008064,GO:0008117,GO:0008150,GO:0008152,GO:0008202,GO:0008209,GO:0008210,GO:0008219,GO:0008406,GO:0008584,GO:0008585,GO:0008610,GO:0009056,GO:0009058,GO:0009267,GO:0009314,GO:0009416,GO:0009453,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009653,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010171,GO:0010646,GO:0010761,GO:0010817,GO:0012501,GO:0012505,GO:0016020,GO:0016021,GO:0016042,GO:0016043,GO:0016477,GO:0016829,GO:0016830,GO:0016832,GO:0019722,GO:0019725,GO:0019752,GO:0019932,GO:0019953,GO:0022414,GO:0022602,GO:0023052,GO:0030003,GO:0030029,GO:0030036,GO:0030097,GO:0030148,GO:0030149,GO:0030154,GO:0030176,GO:0030435,GO:0030587,GO:0030832,GO:0030833,GO:0031156,GO:0031157,GO:0031158,GO:0031224,GO:0031227,GO:0031272,GO:0031273,GO:0031275,GO:0031276,GO:0031344,GO:0031345,GO:0031667,GO:0031668,GO:0031669,GO:0031984,GO:0032101,GO:0032104,GO:0032107,GO:0032271,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032541,GO:0032787,GO:0032956,GO:0032970,GO:0033043,GO:0033327,GO:0033554,GO:0034641,GO:0034754,GO:0035239,GO:0035295,GO:0035556,GO:0040008,GO:0040011,GO:0040014,GO:0042175,GO:0042221,GO:0042330,GO:0042331,GO:0042445,GO:0042592,GO:0042594,GO:0042698,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043436,GO:0043603,GO:0043900,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044703,GO:0045137,GO:0046466,GO:0046467,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0046956,GO:0048008,GO:0048232,GO:0048471,GO:0048511,GO:0048513,GO:0048514,GO:0048519,GO:0048523,GO:0048534,GO:0048583,GO:0048608,GO:0048609,GO:0048638,GO:0048646,GO:0048705,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050830,GO:0050896,GO:0051128,GO:0051129,GO:0051179,GO:0051239,GO:0051493,GO:0051674,GO:0051703,GO:0051704,GO:0051707,GO:0051716,GO:0052128,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0060021,GO:0060176,GO:0060322,GO:0060323,GO:0060324,GO:0060325,GO:0060491,GO:0061061,GO:0061458,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071782,GO:0071840,GO:0071944,GO:0072001,GO:0072358,GO:0072359,GO:0072503,GO:0072507,GO:0080134,GO:0080135,GO:0090066,GO:0090702,GO:0097038,GO:0097190,GO:0098542,GO:0098771,GO:0098827,GO:0099120,GO:0099568,GO:0110053,GO:0120032,GO:0120033,GO:0120035,GO:1901360,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902903 4.1.2.27 ko:K01634,ko:K20704 ko00600,ko01100,ko04071,map00600,map01100,map04071 M00100 R02464,R06516 RC00264,RC00721,RC01266 ko00000,ko00001,ko00002,ko01000,ko04131 - - - Pyridoxal_deC DYD1_k127_2235642_1 331113.SNE_A06490 8.986e-44 168.0 COG0531@1|root,COG0531@2|Bacteria,2JFMI@204428|Chlamydiae 204428|Chlamydiae E Solute carrier family 12 - - - - - - - - - - - - AA_permease,SLC12 DYD1_k127_2241601_3 1444711.CCJF01000005_gene551 1.292e-96 323.0 COG0842@1|root,COG0842@2|Bacteria,2JFXH@204428|Chlamydiae 204428|Chlamydiae V ABC-2 family transporter protein ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD1_k127_2241601_2 1444712.BN1013_00652 7.276e-120 395.0 COG0842@1|root,COG0842@2|Bacteria,2JFF8@204428|Chlamydiae 204428|Chlamydiae V ABC-2 family transporter protein ybhR - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD1_k127_2241601_1 765952.PUV_01670 1.322e-136 449.0 COG1538@1|root,COG1538@2|Bacteria,2JG14@204428|Chlamydiae 204428|Chlamydiae MU Outer membrane efflux protein - - - - - - - - - - - - OEP DYD1_k127_2241601_5 331113.SNE_A01560 6.599e-40 158.0 COG2132@1|root,COG2132@2|Bacteria 2|Bacteria Q Multicopper oxidase - - 1.16.3.3,1.7.2.1 ko:K00368,ko:K22348 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase_2,Cu-oxidase_3,DUF4396 DYD1_k127_2241601_4 331113.SNE_A09430 2.631e-71 250.0 COG0142@1|root,COG0142@2|Bacteria,2JFQ9@204428|Chlamydiae 204428|Chlamydiae H Belongs to the FPP GGPP synthase family crtE - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt DYD1_k127_2241601_0 521097.Coch_0712 1.293e-148 483.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia,1EQ8G@1016|Capnocytophaga 976|Bacteroidetes C Belongs to the UDP-glucose GDP-mannose dehydrogenase family ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_2251948_0 1237149.C900_03605 1.536e-127 409.0 COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,47JZU@768503|Cytophagia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA DYD1_k127_2251948_1 1237149.C900_00736 1.909e-78 267.0 COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,47NAG@768503|Cytophagia 976|Bacteroidetes J PFAM Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans DYD1_k127_2253844_0 765952.PUV_08900 8.145e-71 248.0 COG0313@1|root,COG0313@2|Bacteria,2JFZ5@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase DYD1_k127_2253844_1 331113.SNE_A05870 1.985e-34 133.0 COG0459@1|root,COG0459@2|Bacteria,2JFHN@204428|Chlamydiae 204428|Chlamydiae O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions CP_0968 - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD1_k127_2256864_1 765952.PUV_04820 8.82e-91 304.0 COG1762@1|root,COG1762@2|Bacteria,2JG0E@204428|Chlamydiae 204428|Chlamydiae G PTS system, IIa ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - HTH_17,PTS_EIIA_2 DYD1_k127_2256864_4 716544.wcw_0246 6.363e-47 173.0 COG1762@1|root,COG1762@2|Bacteria,2JG5P@204428|Chlamydiae 204428|Chlamydiae G PTS system, IIa ptsN_1 - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 DYD1_k127_2256864_3 264201.pc0268 7.157e-49 178.0 COG0756@1|root,COG0756@2|Bacteria,2JH0X@204428|Chlamydiae 204428|Chlamydiae F dUTPase - - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase DYD1_k127_2256864_0 1444711.CCJF01000004_gene1887 1.676e-134 434.0 COG0777@1|root,COG0777@2|Bacteria,2JFSB@204428|Chlamydiae 204428|Chlamydiae I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD1_k127_2256864_2 765952.PUV_04780 2.935e-87 292.0 COG0605@1|root,COG0605@2|Bacteria,2JFX8@204428|Chlamydiae 204428|Chlamydiae C radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N DYD1_k127_2256864_5 1444711.CCJF01000004_gene1889 1.39e-24 111.0 COG1587@1|root,COG1587@2|Bacteria,2JGZZ@204428|Chlamydiae 204428|Chlamydiae H Uroporphyrinogen-III synthase HemD - - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 DYD1_k127_2256864_6 1444712.BN1013_00164 9.972e-18 85.0 COG0181@1|root,COG0181@2|Bacteria,2JFY0@204428|Chlamydiae 204428|Chlamydiae H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - HEM4,Porphobil_deam DYD1_k127_2261604_0 264201.pc0261 3.511e-38 145.0 COG0750@1|root,COG0750@2|Bacteria,2JFMQ@204428|Chlamydiae 204428|Chlamydiae M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M50 DYD1_k127_2278283_1 1201288.M900_A0407 1.028e-13 83.0 COG2242@1|root,COG2242@2|Bacteria 2|Bacteria H protein methyltransferase activity - - 2.1.1.303,2.1.1.319 ko:K11434,ko:K20421 ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922 M00830 R10963,R11216,R11217,R11219 RC00003,RC00392,RC02120,RC03388,RC03390 ko00000,ko00001,ko00002,ko01000,ko03036 - - - DOT1,Methyltransf_11,Methyltransf_25 DYD1_k127_2278283_0 1437425.CSEC_0991 3.487e-139 454.0 COG0668@1|root,COG2823@1|root,COG0668@2|Bacteria,COG2823@2|Bacteria,2JGVB@204428|Chlamydiae 204428|Chlamydiae M Mechanosensitive ion channel - - - - - - - - - - - - BON,MS_channel DYD1_k127_229381_5 886377.Murru_0020 0.0008714 46.0 COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1HX0E@117743|Flavobacteriia 976|Bacteroidetes J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD1_k127_229381_2 331113.SNE_A20720 2.328e-44 166.0 COG0615@1|root,COG0615@2|Bacteria 2|Bacteria H ADP-L-glycero-beta-D-manno-heptose biosynthetic process - - 2.7.7.39 ko:K00980 ko00564,map00564 - R00856 RC00002 ko00000,ko00001,ko01000 - - - CTP_transf_like DYD1_k127_229381_0 331113.SNE_A16380 9.377e-107 353.0 COG5285@1|root,COG5285@2|Bacteria 2|Bacteria Q dioxygenase activity - - 1.14.11.46,1.14.11.55 ko:K10674,ko:K21195 ko00260,ko00440,ko01120,map00260,map00440,map01120 - R08050,R10724 RC00661,RC01107 ko00000,ko00001,ko01000 - - - PhyH DYD1_k127_229381_4 5722.XP_001315744.1 9.445e-06 58.0 KOG0597@1|root,KOG0597@2759|Eukaryota 2759|Eukaryota S positive regulation of hh target transcription factor activity MKK2 GO:0000003,GO:0000166,GO:0000278,GO:0000280,GO:0000281,GO:0000910,GO:0000911,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0005874,GO:0005881,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0006996,GO:0007049,GO:0007112,GO:0007140,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007224,GO:0007227,GO:0007228,GO:0007275,GO:0007276,GO:0007349,GO:0007584,GO:0008064,GO:0008092,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008589,GO:0009524,GO:0009553,GO:0009558,GO:0009561,GO:0009605,GO:0009653,GO:0009791,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010639,GO:0010646,GO:0010647,GO:0014070,GO:0015630,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019219,GO:0019222,GO:0019538,GO:0019894,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030010,GO:0030030,GO:0030031,GO:0030554,GO:0030832,GO:0030833,GO:0030837,GO:0031156,GO:0031272,GO:0031323,GO:0031326,GO:0031333,GO:0031344,GO:0031667,GO:0032101,GO:0032104,GO:0032107,GO:0032271,GO:0032272,GO:0032501,GO:0032502,GO:0032504,GO:0032506,GO:0032535,GO:0032553,GO:0032555,GO:0032559,GO:0032956,GO:0032970,GO:0033043,GO:0033206,GO:0033273,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043254,GO:0043326,GO:0043327,GO:0043412,GO:0043900,GO:0044085,GO:0044087,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044782,GO:0045880,GO:0048229,GO:0048232,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048609,GO:0048646,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051321,GO:0051493,GO:0051494,GO:0051593,GO:0051704,GO:0051716,GO:0060176,GO:0060255,GO:0060271,GO:0060491,GO:0061640,GO:0065007,GO:0065008,GO:0065009,GO:0070925,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0097159,GO:0097367,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0110053,GO:0120031,GO:0120032,GO:0120035,GO:0120036,GO:0140013,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901698,GO:1901700,GO:1902410,GO:1902903,GO:1902904,GO:1903046,GO:1903047,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 ko:K06228 ko04341,map04341 - - - ko00000,ko00001,ko01000,ko01001 - - - Arm,HEAT,HEAT_2,HEAT_EZ,Pkinase DYD1_k127_229381_1 768704.Desmer_1527 9.445e-78 280.0 COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,260ZG@186807|Peptococcaceae 186801|Clostridia E PFAM Phenylalanine and histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic DYD1_k127_229381_3 1519464.HY22_12850 4.386e-40 161.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_2295066_1 331113.SNE_A16630 3.299e-227 730.0 COG1026@1|root,COG1026@2|Bacteria,2JFJS@204428|Chlamydiae 204428|Chlamydiae S Peptidase M16C associated CP_0875 - - ko:K06972 - - - - ko00000,ko01000,ko01002 - - - M16C_assoc,Peptidase_M16,Peptidase_M16_C DYD1_k127_2295066_7 1444712.BN1013_00242 1.275e-30 132.0 COG0463@1|root,COG0463@2|Bacteria,2JG4U@204428|Chlamydiae 204428|Chlamydiae M Glycosyltransferase family 92 - - - - - - - - - - - - Glyco_transf_92 DYD1_k127_2295066_3 1123371.ATXH01000003_gene1949 1.373e-131 435.0 COG0265@1|root,COG0265@2|Bacteria,2GHRY@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria O Trypsin - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_2295066_6 297246.lpp0347 7.705e-46 181.0 COG0477@1|root,COG2814@2|Bacteria,1RBJR@1224|Proteobacteria,1S39S@1236|Gammaproteobacteria,1JD9P@118969|Legionellales 118969|Legionellales EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1 DYD1_k127_2295066_5 331113.SNE_A16790 1.554e-86 300.0 COG1994@1|root,COG1994@2|Bacteria,2JFYC@204428|Chlamydiae 204428|Chlamydiae S Tetratricopeptide repeat - - - - - - - - - - - - Peptidase_M50,Peptidase_M50B DYD1_k127_2295066_4 1125863.JAFN01000001_gene1772 5.844e-129 419.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,CoA_binding,Ligase_CoA DYD1_k127_2295066_2 331113.SNE_A16810 6.293e-166 529.0 COG0045@1|root,COG0045@2|Bacteria,2JFW1@204428|Chlamydiae 204428|Chlamydiae F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA DYD1_k127_2295066_8 331113.SNE_A16850 2.065e-27 121.0 2EEU9@1|root,338MT@2|Bacteria,2JGGH@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2295066_0 331113.SNE_A16860 1.198e-234 748.0 COG1198@1|root,COG1198@2|Bacteria,2JFSI@204428|Chlamydiae 204428|Chlamydiae L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Helicase_C,ResIII DYD1_k127_2295066_9 1437425.CSEC_2078 3.612e-18 88.0 COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2JFIF@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I,Shikimate_DH,Shikimate_dh_N DYD1_k127_2332209_3 765952.PUV_00330 3.084e-35 140.0 COG1887@1|root,COG1887@2|Bacteria,2JG2U@204428|Chlamydiae 204428|Chlamydiae M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf DYD1_k127_2332209_1 264201.pc1784 2.747e-51 190.0 COG1442@1|root,COG1442@2|Bacteria,2JG80@204428|Chlamydiae 204428|Chlamydiae M glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 DYD1_k127_2332209_6 1122165.AUHS01000011_gene2588 0.0003083 51.0 COG4106@1|root,COG4106@2|Bacteria,1N21Y@1224|Proteobacteria,1SB4X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0500 SAM-dependent methyltransferases - - - - - - - - - - - - Methyltransf_25 DYD1_k127_2332209_4 768671.ThimaDRAFT_2120 6.737e-12 72.0 29C7G@1|root,3163F@2|Bacteria,1QDGP@1224|Proteobacteria,1TKCK@1236|Gammaproteobacteria,1X1VP@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD1_k127_2332209_2 1123325.JHUV01000010_gene1328 1.748e-46 175.0 COG0035@1|root,COG0035@2|Bacteria 2|Bacteria F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase DYD1_k127_2332209_0 1163617.SCD_n00704 0.0 1323.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria 28216|Betaproteobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N DYD1_k127_2332209_5 1128427.KB904821_gene4090 2.785e-09 61.0 COG0282@1|root,COG0282@2|Bacteria,1G214@1117|Cyanobacteria,1H897@1150|Oscillatoriales 1117|Cyanobacteria C Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase DYD1_k127_2333478_2 1444711.CCJF01000005_gene184 5.04e-63 227.0 COG1472@1|root,COG1472@2|Bacteria,2JG4V@204428|Chlamydiae 204428|Chlamydiae G Glycosyl hydrolase family 3 N terminal domain ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 DYD1_k127_2333478_3 1034943.BN1094_02697 1.837e-48 183.0 COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,1SC68@1236|Gammaproteobacteria,1JETP@118969|Legionellales 118969|Legionellales I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_2333478_0 264201.pc1998 2.865e-87 301.0 COG2265@1|root,COG2265@2|Bacteria,2JGUU@204428|Chlamydiae 204428|Chlamydiae J tRNA (Uracil-5-)-methyltransferase - - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - tRNA_U5-meth_tr DYD1_k127_2333478_1 331113.SNE_A00680 1.603e-65 231.0 COG1207@1|root,COG1207@2|Bacteria,2JG2J@204428|Chlamydiae 204428|Chlamydiae M Bacterial transferase hexapeptide (six repeats) glmU - - - - - - - - - - - Hexapep DYD1_k127_2333478_4 1444711.CCJF01000005_gene441 1.324e-41 156.0 COG0142@1|root,COG0142@2|Bacteria,2JFYA@204428|Chlamydiae 204428|Chlamydiae H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt DYD1_k127_2339217_0 331113.SNE_A22350 2.308e-102 342.0 COG1940@1|root,COG1940@2|Bacteria,2JFZN@204428|Chlamydiae 204428|Chlamydiae GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK DYD1_k127_2339217_3 7897.ENSLACP00000010533 1.267e-34 147.0 KOG2458@1|root,KOG2458@2759|Eukaryota,38FU0@33154|Opisthokonta,3BII9@33208|Metazoa,3D3UG@33213|Bilateria,48BRI@7711|Chordata,48VJN@7742|Vertebrata 33208|Metazoa S KDEL motif-containing protein 2 KDELC2 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0009987,GO:0012505,GO:0016740,GO:0016757,GO:0016758,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046527,GO:0070013,GO:0071704,GO:1901135,GO:1903509 - - - - - - - - - - Filamin,Glyco_transf_90 DYD1_k127_2339217_1 331113.SNE_A22300 1.545e-69 246.0 COG1482@1|root,COG1482@2|Bacteria 2|Bacteria G cell wall glycoprotein biosynthetic process manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - - PMI_typeI,ROK DYD1_k127_2339217_2 56780.SYN_02541 1.496e-56 214.0 COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,2MQRA@213462|Syntrophobacterales 28221|Deltaproteobacteria K Virulence factor BrkB - - - ko:K07058 - - - - ko00000 - - - Rrf2,Virul_fac_BrkB DYD1_k127_2339217_4 1437425.CSEC_0081 7.132e-33 138.0 29XK7@1|root,33SWN@2|Bacteria,2JGTB@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2344599_3 1131269.AQVV01000023_gene2383 1.147e-50 185.0 COG0028@1|root,COG0028@2|Bacteria 2|Bacteria EH Belongs to the TPP enzyme family ilvB2 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_2344599_0 398767.Glov_0789 4.884e-84 291.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WJKR@28221|Deltaproteobacteria,43TT5@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) - - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase DYD1_k127_2344599_2 398767.Glov_0788 2.552e-64 226.0 COG1028@1|root,COG1028@2|Bacteria,1RD0G@1224|Proteobacteria 1224|Proteobacteria IQ RmlD substrate binding domain - - - - - - - - - - - - adh_short_C2 DYD1_k127_2344599_4 1249480.B649_09990 5.081e-47 180.0 COG3836@1|root,COG3836@2|Bacteria,1R78B@1224|Proteobacteria,42PJ0@68525|delta/epsilon subdivisions,2YM8R@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria G HpcH/HpaI aldolase/citrate lyase family - - - - - - - - - - - - HpcH_HpaI DYD1_k127_2344599_1 1210884.HG799466_gene12617 4.862e-72 250.0 COG2518@1|root,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.163,2.1.1.201,2.1.1.77 ko:K00573,ko:K03183,ko:K07003 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - DUF3560,Lant_dehydr_C,Methyltransf_12,Methyltransf_21,NAS,PS-DH DYD1_k127_2344599_5 526224.Bmur_0701 1.437e-13 82.0 COG0463@1|root,COG0463@2|Bacteria,2J8HD@203691|Spirochaetes 203691|Spirochaetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_2359421_1 1444712.BN1013_00216 7.356e-63 218.0 COG0556@1|root,COG0556@2|Bacteria,2JFI1@204428|Chlamydiae 204428|Chlamydiae L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB DYD1_k127_2359421_4 1191523.MROS_0376 5.049e-08 61.0 COG1091@1|root,COG1091@2|Bacteria 2|Bacteria M dTDP-4-dehydrorhamnose reductase activity rmlD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind DYD1_k127_2359421_3 693661.Arcve_0546 3.243e-09 63.0 COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,245XF@183980|Archaeoglobi 183980|Archaeoglobi M TIGRFAM dTDP-4-dehydrorhamnose reductase - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind DYD1_k127_2359421_0 1210884.HG799466_gene12617 1.82e-74 256.0 COG2518@1|root,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.163,2.1.1.201,2.1.1.77 ko:K00573,ko:K03183,ko:K07003 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - DUF3560,Lant_dehydr_C,Methyltransf_12,Methyltransf_21,NAS,PS-DH DYD1_k127_2359421_2 391598.FBBAL38_01825 5.966e-40 159.0 COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,4P2KW@976|Bacteroidetes 976|Bacteroidetes M Glycosyltransferase family 17 - - - - - - - - - - - - Glyco_transf_17 DYD1_k127_2406502_6 673862.BABL1_725 1.013e-06 52.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WNT4@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen prx-2 - 1.11.1.15 ko:K03386,ko:K20011 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA DYD1_k127_2406502_3 331113.SNE_A22570 1.182e-75 259.0 COG0491@1|root,COG0491@2|Bacteria,2JG0X@204428|Chlamydiae 204428|Chlamydiae S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD1_k127_2406502_7 551789.ATVJ01000003_gene39 1.569e-05 47.0 COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom DYD1_k127_2406502_0 660470.Theba_1306 3.915e-253 801.0 COG1982@1|root,COG2199@1|root,COG1982@2|Bacteria,COG3706@2|Bacteria 2|Bacteria T GGDEF domain adiA - 2.7.7.65,4.1.1.19 ko:K01584,ko:K01585,ko:K20955 ko00330,ko01100,ko05111,map00330,map01100,map05111 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N DYD1_k127_2406502_1 716544.wcw_1263 8.023e-158 511.0 COG0531@1|root,COG0531@2|Bacteria,2JFCI@204428|Chlamydiae 204428|Chlamydiae E Amino acid permease - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 DYD1_k127_2406502_5 1173020.Cha6605_5433 6.634e-32 134.0 COG4122@1|root,COG4122@2|Bacteria,1G9N3@1117|Cyanobacteria 1117|Cyanobacteria S Macrocin-O-methyltransferase (TylF) - - - - - - - - - - - - TylF DYD1_k127_2406502_2 765952.PUV_04550 2.882e-91 310.0 COG0569@1|root,COG0569@2|Bacteria,2JFU5@204428|Chlamydiae 204428|Chlamydiae C TrkA-C domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD1_k127_2418405_3 1444712.BN1013_00535 4.952e-54 203.0 COG0793@1|root,COG0793@2|Bacteria,2JFDY@204428|Chlamydiae 204428|Chlamydiae M Belongs to the peptidase S41A family tsp - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 DYD1_k127_2418405_2 331113.SNE_A03290 7.846e-63 217.0 COG0048@1|root,COG0048@2|Bacteria,2JG35@204428|Chlamydiae 204428|Chlamydiae J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 DYD1_k127_2418405_1 1437425.CSEC_2003 1.856e-73 250.0 COG0049@1|root,COG0049@2|Bacteria,2JFZ4@204428|Chlamydiae 204428|Chlamydiae J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 DYD1_k127_2418405_0 331113.SNE_A03270 0.0 1119.0 COG0480@1|root,COG0480@2|Bacteria,2JFJN@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_2418405_4 331113.SNE_A03260 4.3e-50 179.0 COG0051@1|root,COG0051@2|Bacteria,2JG78@204428|Chlamydiae 204428|Chlamydiae J Involved in the binding of tRNA to the ribosomes rpsJ - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 DYD1_k127_2517661_1 716544.wcw_1724 1.147e-81 282.0 COG1055@1|root,COG1055@2|Bacteria,2JFPB@204428|Chlamydiae 204428|Chlamydiae P Putative Na+/H+ antiporter CP_0904 - - - - - - - - - - - Na_H_antiport_3 DYD1_k127_2517661_3 1408444.JHYC01000018_gene312 6.771e-12 73.0 2EN6R@1|root,33FUM@2|Bacteria,1P9EZ@1224|Proteobacteria,1T6XY@1236|Gammaproteobacteria,1JEH9@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - DYD1_k127_2517661_0 331113.SNE_A02070 0.0 1273.0 COG0653@1|root,COG0653@2|Bacteria,2JFI8@204428|Chlamydiae 204428|Chlamydiae U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD1_k127_2517661_2 1033810.HLPCO_000903 6.691e-25 110.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins yokL3 - 2.3.1.57 ko:K00657,ko:K07023 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_3 DYD1_k127_2517661_4 1444711.CCJF01000005_gene324 2.586e-11 66.0 COG0688@1|root,COG0688@2|Bacteria,2JFMN@204428|Chlamydiae 204428|Chlamydiae I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase DYD1_k127_2559008_5 716544.wcw_0640 4.222e-12 74.0 2DZIQ@1|root,32VBQ@2|Bacteria,2JGAZ@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2559008_0 331113.SNE_A10990 2.843e-138 445.0 COG0623@1|root,COG0623@2|Bacteria,2JFHT@204428|Chlamydiae 204428|Chlamydiae I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_2559008_1 673862.BABL1_334 1.967e-80 275.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria 28221|Deltaproteobacteria D PFAM Cobyrinic acid ac-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD1_k127_2559008_3 240015.ACP_0207 8.266e-36 140.0 COG1765@1|root,COG1765@2|Bacteria,3Y7VV@57723|Acidobacteria,2JN4F@204432|Acidobacteriia 204432|Acidobacteriia O OsmC-like protein - - - - - - - - - - - - OsmC DYD1_k127_2559008_4 1437425.CSEC_1340 5.629e-22 107.0 COG1466@1|root,COG1466@2|Bacteria,2JG2N@204428|Chlamydiae 204428|Chlamydiae L dna polymerase III delta subunit - - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta DYD1_k127_2559008_2 1444711.CCJF01000005_gene1209 1.977e-58 210.0 COG0313@1|root,COG0313@2|Bacteria,2JGTN@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA - - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - - DYD1_k127_2572597_0 331113.SNE_A00760 1.378e-28 132.0 COG1196@1|root,COG3209@1|root,COG1196@2|Bacteria,COG3209@2|Bacteria,2JFH5@204428|Chlamydiae 2|Bacteria M Rhs family - - - - - - - - - - - - RHS_repeat DYD1_k127_2572597_1 331113.SNE_A23650 1.368e-17 86.0 2EQNW@1|root,347ZJ@2|Bacteria,2JHB0@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2572886_3 331113.SNE_A03190 2.223e-09 60.0 COG2913@1|root,COG2913@2|Bacteria 2|Bacteria J Gram-negative-bacterium-type cell outer membrane assembly - - - - - - - - - - - - SmpA_OmlA DYD1_k127_2572886_2 331113.SNE_A03180 3.345e-38 148.0 2CDQ1@1|root,32TFM@2|Bacteria,2JG96@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2572886_4 1454004.AW11_02082 8.862e-09 67.0 COG0738@1|root,COG0738@2|Bacteria,1P1TX@1224|Proteobacteria 1224|Proteobacteria G Major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_2572886_0 1444711.CCJF01000005_gene604 1.385e-138 450.0 COG0772@1|root,COG0772@2|Bacteria,2JFPV@204428|Chlamydiae 204428|Chlamydiae D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE DYD1_k127_2572886_1 331113.SNE_A03160 1.671e-57 208.0 COG0340@1|root,COG0340@2|Bacteria,2JG7M@204428|Chlamydiae 204428|Chlamydiae H Biotin/lipoate A/B protein ligase family birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB DYD1_k127_2598136_0 765952.PUV_03190 1.229e-57 206.0 COG0566@1|root,COG0566@2|Bacteria,2JG2W@204428|Chlamydiae 204428|Chlamydiae J SpoU rRNA Methylase family - - - - - - - - - - - - SpoU_methylase DYD1_k127_2598136_1 985867.AEWF01000004_gene109 5.839e-36 142.0 COG0563@1|root,COG0563@2|Bacteria,1Q82N@1224|Proteobacteria,2VE8D@28211|Alphaproteobacteria,47G72@766|Rickettsiales 766|Rickettsiales F adenylate kinase activity - - - - - - - - - - - - - DYD1_k127_2632736_0 1444711.CCJF01000005_gene385 3.048e-138 476.0 COG1074@1|root,COG1074@2|Bacteria,2JFIP@204428|Chlamydiae 204428|Chlamydiae L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C DYD1_k127_2632736_2 716544.wcw_0032 4.019e-80 299.0 COG1330@1|root,COG1330@2|Bacteria,2JFNT@204428|Chlamydiae 204428|Chlamydiae L Exodeoxyribonuclease V, gamma subunit recC - 3.1.11.5 ko:K03583 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_V_gamma DYD1_k127_2632736_3 1444712.BN1013_00242 2.565e-64 231.0 COG0463@1|root,COG0463@2|Bacteria,2JG4U@204428|Chlamydiae 204428|Chlamydiae M Glycosyltransferase family 92 - - - - - - - - - - - - Glyco_transf_92 DYD1_k127_2632736_1 765952.PUV_03710 1.426e-126 424.0 COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,2JFDV@204428|Chlamydiae 204428|Chlamydiae EGP Major Facilitator Superfamily CP_0009 - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - MFS_1 DYD1_k127_2638855_0 1089439.KB902275_gene1722 0.0006244 52.0 COG0738@1|root,COG0738@2|Bacteria,1R8F9@1224|Proteobacteria,1SHK4@1236|Gammaproteobacteria,461UA@72273|Thiotrichales 72273|Thiotrichales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_2662045_6 227086.JGI_V11_89109 4.945e-05 50.0 COG5022@1|root,KOG0160@2759|Eukaryota,KOG4229@2759|Eukaryota 2759|Eukaryota Z motor activity Myo22 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0015629,GO:0016459,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0042623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464 - ko:K10357,ko:K21868 - - - - ko00000,ko03019,ko03029,ko04131,ko04812 - - - FERM_M,IQ,MyTH4,Myosin_N,Myosin_head,RA,WW DYD1_k127_2662045_1 1437425.CSEC_1034 6.947e-33 131.0 COG0199@1|root,COG0199@2|Bacteria,2JG9Y@204428|Chlamydiae 204428|Chlamydiae J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 DYD1_k127_2662045_3 716544.wcw_0804 1.318e-13 71.0 COG0257@1|root,COG0257@2|Bacteria,2JGHY@204428|Chlamydiae 204428|Chlamydiae J Ribosomal protein L36 rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 DYD1_k127_2662045_5 716544.wcw_0805 2.117e-10 61.0 COG0230@1|root,COG0230@2|Bacteria,2JGGK@204428|Chlamydiae 204428|Chlamydiae J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 DYD1_k127_2662045_4 331113.SNE_A18370 4.617e-13 76.0 COG0594@1|root,COG0594@2|Bacteria,2JGGJ@204428|Chlamydiae 204428|Chlamydiae J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P DYD1_k127_2662045_0 1444711.CCJF01000004_gene2364 6.524e-234 739.0 COG0210@1|root,COG0210@2|Bacteria,2JFGH@204428|Chlamydiae 204428|Chlamydiae L UvrD-like helicase C-terminal domain pcrA-A - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD1_k127_2662045_2 1437425.CSEC_1030 8.672e-25 105.0 COG2042@1|root,COG2042@2|Bacteria,2JG7G@204428|Chlamydiae 204428|Chlamydiae S rRNA processing - - - ko:K09140 - - - - ko00000,ko03009 - - - DTW DYD1_k127_2725487_1 716544.wcw_0863 5.498e-42 162.0 COG4166@1|root,COG4166@2|Bacteria,2JFKE@204428|Chlamydiae 204428|Chlamydiae E transmembrane transport - - - - - - - - - - - - - DYD1_k127_2725487_0 1444711.CCJF01000005_gene1734 6.957e-78 268.0 COG0527@1|root,COG0527@2|Bacteria,2JFUC@204428|Chlamydiae 204428|Chlamydiae E Amino acid kinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD1_k127_2725487_2 1444711.CCJF01000005_gene1735 7.836e-31 125.0 COG0539@1|root,COG0539@2|Bacteria,2JFJ4@204428|Chlamydiae 204428|Chlamydiae J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 DYD1_k127_275139_3 331113.SNE_A11440 1.309e-32 131.0 COG0477@1|root,COG2814@2|Bacteria,2JGQX@204428|Chlamydiae 204428|Chlamydiae EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_275139_0 331113.SNE_A10760 4.034e-127 432.0 2DBSG@1|root,2ZAS8@2|Bacteria,2JFD6@204428|Chlamydiae 204428|Chlamydiae - - CP_0861 - - - - - - - - - - - - DYD1_k127_275139_1 331113.SNE_A10800 1.308e-98 335.0 COG1463@1|root,COG1463@2|Bacteria,2JFN3@204428|Chlamydiae 204428|Chlamydiae Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD1_k127_275139_2 331113.SNE_A10810 5.739e-72 246.0 COG1127@1|root,COG1127@2|Bacteria,2JFQY@204428|Chlamydiae 204428|Chlamydiae Q ABC transporter mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD1_k127_2751919_3 525904.Tter_0129 4.824e-18 86.0 COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria 2|Bacteria P Phosphate transporter family pit GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 DYD1_k127_2751919_2 653733.Selin_1030 9.361e-66 230.0 COG0652@1|root,COG0652@2|Bacteria 2|Bacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Hydrolase_3,Pro_isomerase DYD1_k127_2751919_1 1260251.SPISAL_05395 2.716e-82 288.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,1X0EU@135613|Chromatiales 135613|Chromatiales S Permease family - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease DYD1_k127_2751919_0 331113.SNE_A22230 2.42e-105 357.0 COG0707@1|root,COG0707@2|Bacteria,2JG8P@204428|Chlamydiae 204428|Chlamydiae M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - - - - - - - - - - - DYD1_k127_2751919_5 765952.PUV_14240 1.046e-13 78.0 2E07B@1|root,32VV7@2|Bacteria,2JGBW@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2751919_6 1444711.CCJF01000005_gene866 2.048e-07 57.0 29XK7@1|root,33SWN@2|Bacteria,2JGTB@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2776214_4 1444712.BN1013_02318 5.63e-59 207.0 COG0316@1|root,COG0316@2|Bacteria,2JFY5@204428|Chlamydiae 204428|Chlamydiae S Domain of unknown function (DUF1858) iscA - - - - - - - - - - - DUF1858,Fe-S_biosyn DYD1_k127_2776214_1 42099.EPrPV00000021248 9.393e-141 460.0 COG1249@1|root,KOG1335@2759|Eukaryota,1MHB5@121069|Pythiales 121069|Pythiales C Dihydrolipoyl dehydrogenase. Source PGD - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim DYD1_k127_2776214_2 716544.wcw_0998 7.719e-123 404.0 COG0508@1|root,COG0508@2|Bacteria,2JFPZ@204428|Chlamydiae 204428|Chlamydiae C 2-oxoglutarate dehydrogenase sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl DYD1_k127_2776214_0 716544.wcw_0997 1.095e-293 926.0 COG0567@1|root,COG0567@2|Bacteria,2JFWQ@204428|Chlamydiae 204428|Chlamydiae C dehydrogenase e1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr DYD1_k127_2776214_5 331113.SNE_A11060 2.656e-49 179.0 2DMAA@1|root,32BTP@2|Bacteria,2JG6W@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2776214_3 716544.wcw_0983 3.382e-110 366.0 COG0635@1|root,COG0635@2|Bacteria,2JFTP@204428|Chlamydiae 204428|Chlamydiae H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM DYD1_k127_2776214_6 331113.SNE_A23020 3.157e-49 180.0 COG1047@1|root,COG1047@2|Bacteria,2JHGM@204428|Chlamydiae 204428|Chlamydiae O FKBP-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C DYD1_k127_2813579_3 331113.SNE_A00410 3.827e-18 94.0 298AF@1|root,2ZVFZ@2|Bacteria,2JHFY@204428|Chlamydiae 204428|Chlamydiae M In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan ompA GO:0005575,GO:0005576,GO:0005623,GO:0009986,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044464,GO:0065010 - ko:K03162 - - - - ko00000,ko02000 1.B.2.1 - - Chlam_OMP DYD1_k127_2813579_4 264201.pc1545 7.394e-10 63.0 2CG3Q@1|root,336U3@2|Bacteria,2JGDW@204428|Chlamydiae 204428|Chlamydiae S Histone H1-like protein Hc1 hctA - - - - - - - - - - - Hc1 DYD1_k127_2813579_0 716544.wcw_0204 1.361e-143 467.0 COG2265@1|root,COG2265@2|Bacteria,2JFX6@204428|Chlamydiae 204428|Chlamydiae J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - - - - - - - - - - - tRNA_U5-meth_tr DYD1_k127_2813579_2 716544.wcw_0206 6.374e-34 133.0 COG1862@1|root,COG1862@2|Bacteria,2JGA9@204428|Chlamydiae 204428|Chlamydiae U The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF- YajC-YidC subcomplex facilitates these functions yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC DYD1_k127_2813579_1 1444711.CCJF01000004_gene1849 2.989e-43 164.0 COG0326@1|root,COG0326@2|Bacteria,2JFDI@204428|Chlamydiae 204428|Chlamydiae O chaperone protein htpG htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c_3,HSP90 DYD1_k127_2837846_3 316055.RPE_1511 3.879e-49 177.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TRCN@28211|Alphaproteobacteria,3JTVF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB DYD1_k127_2837846_0 1380394.JADL01000001_gene2745 1.481e-147 473.0 COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2TW46@28211|Alphaproteobacteria,2JQV7@204441|Rhodospirillales 204441|Rhodospirillales M Male sterility protein - - - - - - - - - - - - Epimerase DYD1_k127_2837846_1 331869.BAL199_07303 1.033e-142 459.0 COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TTV7@28211|Alphaproteobacteria,4BQC1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M 3-beta hydroxysteroid dehydrogenase/isomerase family - - - - - - - - - - - - Epimerase DYD1_k127_2837846_2 1321778.HMPREF1982_00182 2.953e-80 274.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes 1239|Firmicutes H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA DYD1_k127_2845453_1 331113.SNE_A12270 8.945e-103 342.0 COG1078@1|root,COG1078@2|Bacteria,2JHB7@204428|Chlamydiae 204428|Chlamydiae S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06885 - - - - ko00000 - - - HD DYD1_k127_2845453_0 1444712.BN1013_00874 2.066e-167 534.0 COG0516@1|root,COG0516@2|Bacteria,2JGRE@204428|Chlamydiae 204428|Chlamydiae C IMP dehydrogenase / GMP reductase domain guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - IMPDH DYD1_k127_2845453_2 1437425.CSEC_1691 5.84e-49 186.0 COG0463@1|root,COG0463@2|Bacteria,2JFTY@204428|Chlamydiae 204428|Chlamydiae M Glycosyl transferase family 2 waaE - - - - - - - - - - - Glycos_transf_2 DYD1_k127_2845453_3 765952.PUV_27030 7.452e-18 84.0 COG0463@1|root,COG0463@2|Bacteria,2JFTY@204428|Chlamydiae 204428|Chlamydiae M Glycosyl transferase family 2 waaE - - - - - - - - - - - Glycos_transf_2 DYD1_k127_2845453_4 45351.EDO41242 7.367e-15 87.0 KOG0033@1|root,KOG0033@2759|Eukaryota,38FV7@33154|Opisthokonta,3BF3D@33208|Metazoa 33208|Metazoa T calmodulin-dependent protein kinase activity - - - - - - - - - - - - Pkinase DYD1_k127_285813_1 1056820.KB900632_gene2135 5.967e-35 135.0 COG0847@1|root,COG0847@2|Bacteria,1P2A7@1224|Proteobacteria,1SSAX@1236|Gammaproteobacteria,2PQGP@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - - DYD1_k127_285813_0 1123261.AXDW01000008_gene957 5.501e-88 312.0 2CG4Y@1|root,2Z9HK@2|Bacteria,1R40S@1224|Proteobacteria,1S1GZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_285813_3 1121935.AQXX01000127_gene1209 3.138e-08 66.0 COG0847@1|root,COG0847@2|Bacteria,1P2A7@1224|Proteobacteria,1SSAX@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - - - - - - - - - - - DYD1_k127_285813_2 865937.Gilli_1379 9.243e-16 79.0 28J7B@1|root,2Z92R@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2871027_1 298654.FraEuI1c_1004 2.342e-07 62.0 COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4ES5B@85013|Frankiales 201174|Actinobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2 DYD1_k127_2871027_0 331113.SNE_A09810 1.647e-141 459.0 COG0531@1|root,COG0531@2|Bacteria,2JFCI@204428|Chlamydiae 204428|Chlamydiae E Amino acid permease xasA - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 DYD1_k127_2890221_2 1444712.BN1013_01975 5.65e-06 57.0 2DMSJ@1|root,32TEA@2|Bacteria,2JGUB@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2890221_1 443152.MDG893_02905 2.2e-10 73.0 COG2706@1|root,COG2931@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,1R0AU@1224|Proteobacteria,1S2TT@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - - DYD1_k127_2890221_0 1306947.ARQD01000001_gene899 2.322e-81 282.0 COG0457@1|root,COG0457@2|Bacteria 1306947.ARQD01000001_gene899|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_2890221_3 331113.SNE_A22770 0.0001517 53.0 COG1215@1|root,COG1215@2|Bacteria,2JH6V@204428|Chlamydiae 204428|Chlamydiae M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_2900868_2 331113.SNE_A15260 5.169e-65 235.0 COG1413@1|root,COG1413@2|Bacteria,2JFPT@204428|Chlamydiae 204428|Chlamydiae C lyase activity - - - - - - - - - - - - HEAT_2 DYD1_k127_2900868_4 1444711.CCJF01000004_gene2216 2.931e-45 166.0 COG0537@1|root,COG0537@2|Bacteria,2JG6G@204428|Chlamydiae 204428|Chlamydiae FG catalytic activity CP_0266 - - - - - - - - - - - HIT DYD1_k127_2900868_1 331113.SNE_A15280 8.317e-116 379.0 COG4286@1|root,COG4286@2|Bacteria,2JFGF@204428|Chlamydiae 204428|Chlamydiae S conserved protein related to MYG1 family CP_0265 - - - - - - - - - - - UPF0160 DYD1_k127_2900868_3 118163.Ple7327_2411 1.402e-59 209.0 COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,3VN4P@52604|Pleurocapsales 1117|Cyanobacteria G Raf kinase inhibitor-like protein, YbhB YbcL family - - - ko:K06910 - - - - ko00000 - - - PBP DYD1_k127_2900868_0 716544.wcw_0569 2.024e-134 440.0 COG1611@1|root,COG1611@2|Bacteria,2JFEZ@204428|Chlamydiae 204428|Chlamydiae S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - - DYD1_k127_2951463_1 1121937.AUHJ01000011_gene2889 6.894e-27 117.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,464U6@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG2133 Glucose sorbosone dehydrogenases - - - ko:K21430 - - - - ko00000,ko01000 - - - Cytochrome_CBB3,GSDH DYD1_k127_2951463_0 331113.SNE_A14690 2.458e-148 475.0 COG0180@1|root,COG0180@2|Bacteria,2JFCD@204428|Chlamydiae 204428|Chlamydiae J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b DYD1_k127_2960215_1 716544.wcw_1230 8.929e-135 441.0 COG0621@1|root,COG0621@2|Bacteria,2JFUS@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine mtaB - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 DYD1_k127_2960215_0 1444711.CCJF01000005_gene1285 1.204e-148 482.0 COG2262@1|root,COG2262@2|Bacteria,2JFSR@204428|Chlamydiae 204428|Chlamydiae S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 DYD1_k127_2960215_2 765952.PUV_14920 7.411e-77 265.0 COG1235@1|root,COG1235@2|Bacteria,2JFXZ@204428|Chlamydiae 204428|Chlamydiae S Metallo-beta-lactamase superfamily phnP - 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 DYD1_k127_2960215_6 765952.PUV_14540 1.246e-38 155.0 COG0665@1|root,COG0665@2|Bacteria,2JG6M@204428|Chlamydiae 204428|Chlamydiae E Oxidoreductase CP_0822 - - - - - - - - - - - DAO DYD1_k127_2960215_4 331113.SNE_A07060 3.214e-66 235.0 28JQF@1|root,2Z9GB@2|Bacteria,2JFW5@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_2960215_3 673862.BABL1_734 3.316e-76 266.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42S93@68525|delta/epsilon subdivisions,2X5GZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_2960215_5 673862.BABL1_44 6.908e-55 202.0 COG1682@1|root,COG1682@2|Bacteria,1QXTH@1224|Proteobacteria,42XN1@68525|delta/epsilon subdivisions,2WSPR@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD1_k127_30387_0 331113.SNE_A22140 8.902e-46 169.0 COG0558@1|root,COG0558@2|Bacteria,2JG6R@204428|Chlamydiae 204428|Chlamydiae I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA_1 - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD1_k127_30387_1 1173028.ANKO01000052_gene1653 7.962e-29 127.0 COG0457@1|root,COG0457@2|Bacteria,1GAAM@1117|Cyanobacteria,1HDEW@1150|Oscillatoriales 1117|Cyanobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 DYD1_k127_30387_2 1173028.ANKO01000052_gene1653 1.16e-22 100.0 COG0457@1|root,COG0457@2|Bacteria,1GAAM@1117|Cyanobacteria,1HDEW@1150|Oscillatoriales 1117|Cyanobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_1 DYD1_k127_3040829_0 331113.SNE_A06420 1.468e-107 359.0 COG0659@1|root,COG0659@2|Bacteria,2JFQW@204428|Chlamydiae 204428|Chlamydiae P Sulfate transporter family ychM - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp DYD1_k127_3040829_1 748449.Halha_0209 5.919e-56 203.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WAJC@53433|Halanaerobiales 186801|Clostridia F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - iHN637.CLJU_RS20110 ADK,ADK_lid DYD1_k127_3040829_4 264462.Bd0909 7.464e-26 112.0 COG1764@1|root,COG1764@2|Bacteria,1RJIP@1224|Proteobacteria 1224|Proteobacteria O redox protein regulator of disulfide bond formation - - - - - - - - - - - - OsmC DYD1_k127_3040829_2 331113.SNE_A12040 3.703e-33 140.0 COG0666@1|root,COG2940@1|root,COG0666@2|Bacteria,COG2940@2|Bacteria,2JG8R@204428|Chlamydiae 204428|Chlamydiae S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain set - - ko:K07117 - - - - ko00000 - - - SET DYD1_k127_3040829_3 1229831.M832_06660 6.958e-30 126.0 COG2940@1|root,COG2940@2|Bacteria,2JG8R@204428|Chlamydiae 204428|Chlamydiae S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain set - - ko:K07117 - - - - ko00000 - - - SET DYD1_k127_3045932_2 331113.SNE_A18000 1.216e-93 317.0 COG0501@1|root,COG0501@2|Bacteria,2JFUN@204428|Chlamydiae 204428|Chlamydiae O Peptidase family M48 - - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 DYD1_k127_3045932_4 716544.wcw_0837 1.722e-10 64.0 2DSAT@1|root,33F9Y@2|Bacteria,2JGI6@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3045932_0 765952.PUV_25990 3.079e-131 432.0 COG0624@1|root,COG0624@2|Bacteria,2JFTI@204428|Chlamydiae 204428|Chlamydiae E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD1_k127_3045932_5 1444711.CCJF01000004_gene2416 7.97e-08 65.0 COG1196@1|root,COG1196@2|Bacteria,2JGWU@204428|Chlamydiae 204428|Chlamydiae D nuclear chromosome segregation - - - - - - - - - - - - - DYD1_k127_3045932_1 1237149.C900_03538 1.642e-123 406.0 COG0451@1|root,COG0451@2|Bacteria,4NI6B@976|Bacteroidetes,47UHB@768503|Cytophagia 976|Bacteroidetes GM RmlD substrate binding domain - - - - - - - - - - - - Epimerase DYD1_k127_3045932_3 643867.Ftrac_2079 1.738e-92 318.0 COG0451@1|root,COG2217@1|root,COG0451@2|Bacteria,COG2217@2|Bacteria 2|Bacteria P Heavy metal translocating P-type atpase - - 2.3.1.94,3.6.3.3,3.6.3.5,5.1.3.2 ko:K01534,ko:K01784,ko:K10817,ko:K12443,ko:K15672 ko00052,ko00520,ko00522,ko01051,ko01052,ko01100,ko01130,map00052,map00520,map00522,map01051,map01052,map01100,map01130 M00361,M00362,M00632,M00774 R00291,R00918,R02984 RC00004,RC00289,RC02825,RC02826,RC02828,RC02829,RC02830,RC02831 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 3.A.3.6 - - Acyl_transf_1,Epimerase,HMA,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,VKOR,ketoacyl-synt DYD1_k127_3071159_3 1408422.JHYF01000002_gene2590 3.499e-27 112.0 COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,36ED0@31979|Clostridiaceae 186801|Clostridia S tigr00255 yicC - - - - - - - - - - - DUF1732,YicC_N DYD1_k127_3071159_1 1444711.CCJF01000005_gene1764 2.003e-63 223.0 COG0194@1|root,COG0194@2|Bacteria,2JG3V@204428|Chlamydiae 204428|Chlamydiae F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin DYD1_k127_3071159_0 765952.PUV_18630 2.151e-264 831.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,2JFFM@204428|Chlamydiae 204428|Chlamydiae J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind DYD1_k127_3071159_2 264201.pc0689 2.23e-40 151.0 COG0507@1|root,COG0507@2|Bacteria,2JFJU@204428|Chlamydiae 204428|Chlamydiae L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 DYD1_k127_3090683_8 1469948.JPNB01000002_gene4067 4.345e-08 61.0 COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,247TS@186801|Clostridia,36F14@31979|Clostridiaceae 186801|Clostridia Q PFAM Collagen triple helix repeat - - - - - - - - - - - - Collagen DYD1_k127_3090683_3 331113.SNE_A22770 1.195e-60 220.0 COG1215@1|root,COG1215@2|Bacteria,2JH6V@204428|Chlamydiae 204428|Chlamydiae M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_3090683_4 331113.SNE_A02170 1.463e-55 203.0 COG0632@1|root,COG0632@2|Bacteria,2JG4N@204428|Chlamydiae 204428|Chlamydiae L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N DYD1_k127_3090683_5 1444711.CCJF01000005_gene328 2.251e-54 195.0 COG0817@1|root,COG0817@2|Bacteria,2JG3D@204428|Chlamydiae 204428|Chlamydiae L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC DYD1_k127_3090683_1 716544.wcw_1790 1.666e-109 364.0 COG0859@1|root,COG0859@2|Bacteria,2JFNJ@204428|Chlamydiae 204428|Chlamydiae M Glycosyltransferase family 9 (heptosyltransferase) rfaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_3090683_2 331113.SNE_A02200 5.394e-75 273.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - - - - - - - - - - Glyco_transf_9,TPR_2 DYD1_k127_3090683_7 765952.PUV_25530 7.717e-33 145.0 COG4284@1|root,COG4284@2|Bacteria,2JFER@204428|Chlamydiae 204428|Chlamydiae G UDP-N-acetylglucosamine pyrophosphorylase CP_1013 - 2.7.7.23,2.7.7.83 ko:K00972 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00361,M00362 R00416 RC00002 ko00000,ko00001,ko00002,ko01000 - - - UDPGP DYD1_k127_3090683_0 331113.SNE_A02230 2.065e-121 397.0 COG0240@1|root,COG0240@2|Bacteria,2JFRP@204428|Chlamydiae 204428|Chlamydiae I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N DYD1_k127_3090683_6 331113.SNE_A02240 3.255e-33 134.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2JFGW@204428|Chlamydiae 204428|Chlamydiae H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD1_k127_31018_1 331113.SNE_A18970 3.519e-24 111.0 COG1714@1|root,COG1714@2|Bacteria 2|Bacteria S RDD family - - - - - - - - - - - - DUF4339,MerR_1,RDD DYD1_k127_31018_0 240292.Ava_4664 0.0 1035.0 COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1HIIK@1161|Nostocales 1117|Cyanobacteria CJ TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig DYD1_k127_3108558_4 634500.EbC_10020 3.707e-38 145.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,3X684@551|Erwinia 1236|Gammaproteobacteria C Belongs to the heme-copper respiratory oxidase family cyoB GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0019646,GO:0020037,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0043167,GO:0043169,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901363,GO:1902494,GO:1902600 1.10.3.10 ko:K02298 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX1 DYD1_k127_3108558_3 10228.TriadP35138 5.094e-68 236.0 COG1845@1|root,2S4Q5@2759|Eukaryota,3A7PT@33154|Opisthokonta,3BT3C@33208|Metazoa 33208|Metazoa C Cytochrome c oxidase subunit - - - - - - - - - - - - COX3 DYD1_k127_3108558_5 331113.SNE_A16300 1.136e-30 124.0 COG3125@1|root,COG3125@2|Bacteria,2JGFM@204428|Chlamydiae 204428|Chlamydiae C Prokaryotic Cytochrome C oxidase subunit IV cyoD - - ko:K02300 ko00190,ko01100,map00190,map01100 M00417 - - ko00000,ko00001,ko00002 3.D.4.5 - - COX4_pro DYD1_k127_3108558_6 7719.XP_009857954.1 1.638e-29 131.0 COG5599@1|root,KOG4228@2759|Eukaryota,38C1K@33154|Opisthokonta,3BJP8@33208|Metazoa,3CVMT@33213|Bilateria,487DP@7711|Chordata 33208|Metazoa T positive regulation of oligodendrocyte differentiation - - 3.1.3.48 ko:K18032 - - - - ko00000,ko01000,ko01009 - - - Y_phosphatase DYD1_k127_3108558_0 331113.SNE_A03720 1.151e-201 641.0 COG0473@1|root,COG0473@2|Bacteria,2JFP7@204428|Chlamydiae 204428|Chlamydiae C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD1_k127_3108558_2 716544.wcw_1729 9.251e-110 363.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,2JFVE@204428|Chlamydiae 204428|Chlamydiae M Belongs to the SIS family. GutQ KpsF subfamily kpsF - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS DYD1_k127_3108558_1 391625.PPSIR1_30010 4.462e-139 454.0 COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2WKSV@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Na H antiporter - - - - - - - - - - - - CitMHS DYD1_k127_3108558_7 331113.SNE_A23370 3.39e-23 113.0 COG3468@1|root,COG3468@2|Bacteria,2JHAK@204428|Chlamydiae 204428|Chlamydiae MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - - DYD1_k127_3125563_0 716544.wcw_0742 1.576e-78 271.0 COG1090@1|root,COG1090@2|Bacteria,2JFV6@204428|Chlamydiae 204428|Chlamydiae S Domain of unknown function (DUF1731) - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase DYD1_k127_3125563_4 349521.HCH_02916 2.035e-12 75.0 2A39Z@1|root,30RRY@2|Bacteria,1PAPY@1224|Proteobacteria,1SWCC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Yip1 domain - - - - - - - - - - - - Yip1 DYD1_k127_3125563_3 331113.SNE_A11400 1.138e-28 124.0 2DNAV@1|root,32WHG@2|Bacteria 2|Bacteria S Yip1 domain - - - - - - - - - - - - Yip1 DYD1_k127_3125563_2 331113.SNE_A11410 1.391e-36 145.0 2DR86@1|root,33AMR@2|Bacteria,2JHI9@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3125563_1 1437425.CSEC_0966 1.142e-38 156.0 2DUU3@1|root,33S9I@2|Bacteria,2JGYS@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3125563_5 1401065.HMPREF2130_04820 4.852e-07 53.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,3T2NZ@506|Alcaligenaceae 28216|Betaproteobacteria L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N DYD1_k127_3140582_0 1444711.CCJF01000004_gene1955 2.061e-153 495.0 COG0124@1|root,COG0124@2|Bacteria,2JFJ0@204428|Chlamydiae 204428|Chlamydiae J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD1_k127_3140582_2 331113.SNE_A21670 4.36e-15 79.0 COG0545@1|root,COG0545@2|Bacteria,2JFN0@204428|Chlamydiae 204428|Chlamydiae M Peptidyl-prolyl cis-trans mip - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C,FKBP_N DYD1_k127_3140582_1 1444712.BN1013_00945 2.221e-61 215.0 COG0219@1|root,COG0219@2|Bacteria,2JG5G@204428|Chlamydiae 204428|Chlamydiae J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD1_k127_314671_1 1444711.CCJF01000005_gene1190 3.002e-163 527.0 COG2239@1|root,COG2239@2|Bacteria,2JFJ8@204428|Chlamydiae 204428|Chlamydiae P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD1_k127_314671_0 264201.pc1116 2.008e-281 875.0 COG1217@1|root,COG1217@2|Bacteria,2JFS9@204428|Chlamydiae 204428|Chlamydiae T Elongation factor G C-terminus typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_3147250_1 1444711.CCJF01000004_gene2400 3.667e-26 118.0 COG0563@1|root,COG0563@2|Bacteria 2|Bacteria F adenylate kinase activity adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid DYD1_k127_3147250_0 1123355.JHYO01000011_gene1454 1.184e-147 487.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,36XKR@31993|Methylocystaceae 28211|Alphaproteobacteria V ABC transporter transmembrane region atm1 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_3147250_2 312284.A20C1_08233 3.266e-22 111.0 COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria 201174|Actinobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_3147250_4 483218.BACPEC_03077 2.368e-20 108.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia 186801|Clostridia E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_3147250_5 614083.AWQR01000022_gene81 1.131e-18 102.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,4AAEX@80864|Comamonadaceae 28216|Betaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_3147250_3 1316927.ATKI01000039_gene2388 1.197e-20 106.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RQKU@1236|Gammaproteobacteria,1YT10@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E Aminotransferase class-III dat - 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_3168045_1 765952.PUV_06830 7.083e-97 325.0 COG0793@1|root,COG0793@2|Bacteria,2JFDY@204428|Chlamydiae 204428|Chlamydiae M Belongs to the peptidase S41A family tsp - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 DYD1_k127_3168045_2 82654.Pse7367_3539 3.463e-25 109.0 COG3654@1|root,COG3654@2|Bacteria,1G71M@1117|Cyanobacteria,1HBPW@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Filamentation induced by cAMP death on curing-related - - - ko:K07341 - - - - ko00000,ko02048 - - - Fic DYD1_k127_3183414_2 264201.pc0815 1.408e-52 190.0 COG1136@1|root,COG1136@2|Bacteria,2JFYR@204428|Chlamydiae 204428|Chlamydiae V system ATP-binding protein LolD lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran DYD1_k127_3183414_0 331113.SNE_A09460 4.123e-118 395.0 COG4591@1|root,COG4591@2|Bacteria,2JHHC@204428|Chlamydiae 204428|Chlamydiae M FtsX-like permease family - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX DYD1_k127_3183414_3 331113.SNE_A09470 5.056e-18 85.0 COG0267@1|root,COG0267@2|Bacteria,2JGJK@204428|Chlamydiae 204428|Chlamydiae J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 DYD1_k127_3183414_1 1437425.CSEC_0771 4.763e-108 359.0 COG0533@1|root,COG0533@2|Bacteria,2JFFE@204428|Chlamydiae 204428|Chlamydiae J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 DYD1_k127_3183414_4 169963.lmo1079 5.674e-05 51.0 COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,4HD9X@91061|Bacilli,26MB6@186820|Listeriaceae 91061|Bacilli S Bacterial membrane protein YfhO yfhO - - - - - - - - - - - YfhO DYD1_k127_3189042_2 264201.pc0751 6.692e-49 191.0 2DE6Q@1|root,2ZKQS@2|Bacteria,2JHE7@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3189042_3 765952.PUV_23760 0.0002964 44.0 COG4043@1|root,COG4043@2|Bacteria 2|Bacteria - - nudA - - - - - - - - - - - ASCH,NUDIX DYD1_k127_3189042_1 1444711.CCJF01000005_gene901 2.095e-76 265.0 COG3108@1|root,COG3108@2|Bacteria,2JG29@204428|Chlamydiae 204428|Chlamydiae S Peptidase M15 - - - - - - - - - - - - Peptidase_M15_3 DYD1_k127_3189042_0 1437425.CSEC_0145 1.061e-97 334.0 COG5000@1|root,COG5000@2|Bacteria,2JHI0@204428|Chlamydiae 204428|Chlamydiae T PAS domain - - 2.7.13.3 ko:K07710 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD1_k127_3215646_0 331113.SNE_A11180 2.706e-37 143.0 COG0563@1|root,COG0563@2|Bacteria,2JH6Z@204428|Chlamydiae 204428|Chlamydiae F adenylate kinase - - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK DYD1_k127_3215646_1 1229831.M832_02340 6.976e-35 134.0 COG0633@1|root,COG0633@2|Bacteria,2JGF0@204428|Chlamydiae 204428|Chlamydiae C 2Fe-2S iron-sulfur cluster binding domain fdxC - - - - - - - - - - - Fer2 DYD1_k127_3215646_2 331113.SNE_A11160 3.043e-06 49.0 COG0316@1|root,COG0316@2|Bacteria,2JFY5@204428|Chlamydiae 204428|Chlamydiae S Domain of unknown function (DUF1858) iscA - - - - - - - - - - - DUF1858,Fe-S_biosyn DYD1_k127_322463_0 5932.XP_004023960.1 1.642e-96 326.0 COG0462@1|root,KOG1448@2759|Eukaryota,3ZAN6@5878|Ciliophora 5878|Ciliophora EF N-terminal domain of ribose phosphate pyrophosphokinase - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N DYD1_k127_322463_1 1519464.HY22_03040 1.131e-11 66.0 COG1051@1|root,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity nudF1 - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX DYD1_k127_3294434_2 264201.pc0259 4.856e-61 221.0 COG1108@1|root,COG1108@2|Bacteria,2JFM1@204428|Chlamydiae 204428|Chlamydiae P transport system membrane protein ytgD - - ko:K11709 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC-3 DYD1_k127_3294434_0 264201.pc0260 6.122e-138 448.0 COG0743@1|root,COG0743@2|Bacteria,2JFM0@204428|Chlamydiae 204428|Chlamydiae I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom DYD1_k127_3294434_1 716544.wcw_0357 1.189e-63 221.0 COG0750@1|root,COG0750@2|Bacteria,2JFMQ@204428|Chlamydiae 204428|Chlamydiae M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M50 DYD1_k127_3302983_7 926564.KI911625_gene4029 2.28e-19 97.0 COG0242@1|root,COG0242@2|Bacteria,2GNZ9@201174|Actinobacteria,4F4G9@85017|Promicromonosporaceae 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD1_k127_3302983_6 331113.SNE_A04440 4.352e-20 98.0 COG2518@1|root,COG2518@2|Bacteria 2|Bacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - Methyltransf_25,Methyltransf_31,rRNA_methylase DYD1_k127_3302983_1 765952.PUV_21400 2.886e-61 221.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - ko:K06889 - - - - ko00000 - - - BAAT_C,Bile_Hydr_Trans DYD1_k127_3302983_2 716544.wcw_0559 1.529e-58 211.0 COG1878@1|root,COG1878@2|Bacteria,2JGBB@204428|Chlamydiae 204428|Chlamydiae K Putative cyclase - - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase DYD1_k127_3302983_3 1121285.AUFK01000018_gene636 4.013e-52 198.0 COG4188@1|root,COG4188@2|Bacteria,4NHAZ@976|Bacteroidetes,1I5YR@117743|Flavobacteriia,3ZT6Z@59732|Chryseobacterium 976|Bacteroidetes S Platelet-activating factor acetylhydrolase, isoform II - - - - - - - - - - - - PAF-AH_p_II DYD1_k127_3302983_5 709032.Sulku_0548 6.199e-34 135.0 COG3012@1|root,COG3012@2|Bacteria,1Q5V3@1224|Proteobacteria,42UFW@68525|delta/epsilon subdivisions,2YPTX@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S SEC-C motif - - - ko:K09858 - - - - ko00000 - - - SEC-C DYD1_k127_3302983_0 765952.PUV_04630 5.3e-127 418.0 COG1114@1|root,COG1114@2|Bacteria,2JGMS@204428|Chlamydiae 204428|Chlamydiae E Branched-chain amino acid transport protein - - - - - - - - - - - - Branch_AA_trans DYD1_k127_3302983_4 1047013.AQSP01000142_gene222 3.306e-41 158.0 COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria 2|Bacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471 DYD1_k127_330937_2 1174504.AJTN02000248_gene3771 5.636e-40 155.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,1ZGDP@1386|Bacillus 91061|Bacilli D septum formation protein Maf maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K06287 - - - - ko00000 - - - Maf DYD1_k127_330937_1 331113.SNE_A08970 2.051e-133 444.0 COG1413@1|root,COG1413@2|Bacteria,2JFT5@204428|Chlamydiae 204428|Chlamydiae C lyase activity CP_0755 - - - - - - - - - - - HEAT_2 DYD1_k127_330937_0 331113.SNE_A08960 8.485e-151 501.0 COG1452@1|root,COG1452@2|Bacteria,2JFGN@204428|Chlamydiae 204428|Chlamydiae M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane CP_0756 - - - - - - - - - - - - DYD1_k127_330937_3 1242864.D187_005303 4.069e-28 116.0 COG1063@1|root,COG1063@2|Bacteria,1NXSN@1224|Proteobacteria,438FZ@68525|delta/epsilon subdivisions,2X3QX@28221|Deltaproteobacteria,2YWVR@29|Myxococcales 28221|Deltaproteobacteria E Glucose dehydrogenase C-terminus gcd - - - - - - - - - - - ADH_N,Glu_dehyd_C DYD1_k127_3314896_0 671143.DAMO_0963 3.453e-120 394.0 COG3696@1|root,COG3696@2|Bacteria,2NNKZ@2323|unclassified Bacteria 2|Bacteria P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family cusA - - ko:K07787,ko:K15726 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.2,2.A.6.1.4 - iAF987.Gmet_1547 ACR_tran DYD1_k127_3332231_0 765952.PUV_02450 5.567e-115 385.0 COG0553@1|root,COG0553@2|Bacteria,2JFHJ@204428|Chlamydiae 204428|Chlamydiae L swi snf helicase family - - - - - - - - - - - - Helicase_C,SNF2_N DYD1_k127_3332231_3 338966.Ppro_1338 1.379e-26 114.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria,43VFA@69541|Desulfuromonadales 28221|Deltaproteobacteria H 6-O-methylguanine DNA methyltransferase, DNA binding domain ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N DYD1_k127_3332231_1 765952.PUV_11720 1.489e-70 251.0 COG2849@1|root,COG2849@2|Bacteria,2JG13@204428|Chlamydiae 204428|Chlamydiae S repeat protein CP_0153 - - - - - - - - - - - MORN_2 DYD1_k127_3332231_2 1444712.BN1013_00929 8.396e-38 147.0 COG0072@1|root,COG0072@2|Bacteria,2JFCR@204428|Chlamydiae 204428|Chlamydiae J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind DYD1_k127_335236_0 264201.pc0728 3.441e-140 451.0 COG0542@1|root,COG0542@2|Bacteria,2JFW9@204428|Chlamydiae 204428|Chlamydiae O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD1_k127_335236_3 1444712.BN1013_01211 3.076e-42 159.0 COG2912@1|root,COG2912@2|Bacteria,2JFGS@204428|Chlamydiae 204428|Chlamydiae S Transglutaminase-like superfamily CP_0628 - - - - - - - - - - - TPR_8,Transglut_core2 DYD1_k127_335236_1 331113.SNE_A17720 1.65e-115 381.0 COG0457@1|root,COG2912@1|root,COG0457@2|Bacteria,COG2912@2|Bacteria,2JFGS@204428|Chlamydiae 204428|Chlamydiae S Transglutaminase-like superfamily CP_0628 - - - - - - - - - - - TPR_8,Transglut_core2 DYD1_k127_335236_6 148304.MAPG_09010T0 6.107e-06 54.0 COG0553@1|root,KOG0298@2759|Eukaryota,38QEB@33154|Opisthokonta,3NW30@4751|Fungi,3QPWM@4890|Ascomycota,218BP@147550|Sordariomycetes,41JUQ@639021|Magnaporthales 4751|Fungi L ATP-dependent DNA helicase - GO:0000228,GO:0000724,GO:0000725,GO:0000726,GO:0000785,GO:0000790,GO:0003674,GO:0003824,GO:0004386,GO:0004842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006310,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016567,GO:0016740,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019787,GO:0031974,GO:0031981,GO:0032446,GO:0033554,GO:0034641,GO:0036211,GO:0042623,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0045003,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0061630,GO:0061659,GO:0070013,GO:0070647,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.2.27 ko:K15710 - - - - ko00000,ko01000,ko04121 - - - Helicase_C,SNF2_N,zf-C3HC4,zf-C3HC4_2,zf-C3HC4_3,zf-RING_2 DYD1_k127_335236_2 331113.SNE_A17880 1.216e-114 383.0 COG1640@1|root,COG1640@2|Bacteria,2JFE9@204428|Chlamydiae 204428|Chlamydiae G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 DYD1_k127_335236_4 156889.Mmc1_3670 2.438e-14 74.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus DYD1_k127_3372838_0 1444711.CCJF01000005_gene1664 2.319e-118 386.0 COG1092@1|root,COG1092@2|Bacteria,2JFKR@204428|Chlamydiae 204428|Chlamydiae J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM DYD1_k127_3372838_1 671143.DAMO_1059 3.933e-51 192.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - - - - - - - - - - - Epimerase,NAD_binding_10 DYD1_k127_3372838_3 211114.JOEF01000008_gene1320 2.734e-06 59.0 COG3568@1|root,COG3568@2|Bacteria,2GNC4@201174|Actinobacteria,4DYVI@85010|Pseudonocardiales 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family - - 3.1.4.12,3.1.4.3 ko:K01114,ko:K01117 ko00562,ko00564,ko00565,ko00600,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map00600,map01100,map01110,map02024,map04919 - R01312,R02027,R02052,R02541,R03332,R07381 RC00017,RC00425 ko00000,ko00001,ko01000,ko02042 - - - Exo_endo_phos DYD1_k127_3372838_2 673862.BABL1_731 2.775e-40 165.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 DYD1_k127_3379883_1 331113.SNE_A06010 6.779e-61 213.0 COG0037@1|root,COG0037@2|Bacteria,2JFSJ@204428|Chlamydiae 204428|Chlamydiae H Belongs to the TtcA family ttcA - - - - - - - - - - - ATP_bind_3 DYD1_k127_3379883_0 331113.SNE_A06000 9.314e-166 534.0 COG0591@1|root,COG0591@2|Bacteria,2JFMA@204428|Chlamydiae 204428|Chlamydiae E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF DYD1_k127_3391419_2 331113.SNE_A05090 5.213e-15 85.0 COG3468@1|root,COG3468@2|Bacteria 2|Bacteria MU cell adhesion - - - ko:K02024 - - - - ko00000,ko02000 1.B.3.1.1 - - Autotransporter,NIDO,OMP_b-brl,VPEP DYD1_k127_3391419_1 331113.SNE_A08500 3.286e-27 124.0 COG3468@1|root,COG3468@2|Bacteria,2JGG3@204428|Chlamydiae 204428|Chlamydiae MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - - DYD1_k127_3391419_0 331113.SNE_A23420 4.447e-36 151.0 COG3468@1|root,COG3468@2|Bacteria,2JHAK@204428|Chlamydiae 204428|Chlamydiae MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - - DYD1_k127_3399670_0 765952.PUV_01320 1.742e-160 511.0 COG1186@1|root,COG1186@2|Bacteria,2JFVB@204428|Chlamydiae 204428|Chlamydiae J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD1_k127_3399670_4 331113.SNE_A18770 7.892e-47 173.0 COG1670@1|root,COG1670@2|Bacteria,2JHHU@204428|Chlamydiae 204428|Chlamydiae J Acetyltransferase (GNAT) domain - - - ko:K03825 - - - - ko00000,ko01000 - - - Acetyltransf_1 DYD1_k127_3399670_3 1444711.CCJF01000005_gene964 7.372e-50 182.0 COG1670@1|root,COG1670@2|Bacteria,2JGRB@204428|Chlamydiae 204428|Chlamydiae J FR47-like protein - - - ko:K03825 - - - - ko00000,ko01000 - - - - DYD1_k127_3399670_5 378806.STAUR_6859 1.205e-31 132.0 COG1451@1|root,COG1451@2|Bacteria,1P1X1@1224|Proteobacteria,4314C@68525|delta/epsilon subdivisions,2WX53@28221|Deltaproteobacteria,2YY4V@29|Myxococcales 28221|Deltaproteobacteria S nucleotide metabolic process - - - - - - - - - - - - - DYD1_k127_3399670_1 264201.pc1328 1.34e-98 327.0 COG0217@1|root,COG0217@2|Bacteria,2JFMK@204428|Chlamydiae 204428|Chlamydiae K Transcriptional Regulatory Protein CP_0176 - - - - - - - - - - - Transcrip_reg DYD1_k127_3399670_2 716544.wcw_0398 1.804e-50 187.0 COG1025@1|root,COG1025@2|Bacteria,2JFKH@204428|Chlamydiae 204428|Chlamydiae O insulinase family ide - 3.4.24.56 ko:K01408 ko05010,map05010 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M DYD1_k127_3407197_1 331113.SNE_A19590 1.129e-18 89.0 COG0544@1|root,COG0544@2|Bacteria,2JG2G@204428|Chlamydiae 204428|Chlamydiae D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - Trigger_C,Trigger_N DYD1_k127_3407197_0 331113.SNE_A19580 1.525e-229 731.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2JFDP@204428|Chlamydiae 204428|Chlamydiae KL SNF2 family CP_1020 - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM DYD1_k127_3413011_0 765952.PUV_10100 6.848e-175 563.0 COG0557@1|root,COG0557@2|Bacteria,2JFD4@204428|Chlamydiae 204428|Chlamydiae J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 DYD1_k127_3413011_2 4950.XP_003680152.1 2.961e-54 196.0 COG2094@1|root,KOG4486@2759|Eukaryota,39RQW@33154|Opisthokonta 33154|Opisthokonta L DNA-7-methyladenine glycosylase activity - - - - - - - - - - - - Pur_DNA_glyco DYD1_k127_3413011_1 1229831.M832_00690 1.749e-54 198.0 COG2928@1|root,COG2928@2|Bacteria,2JFZV@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF502) CP_0247 - - - - - - - - - - - DUF502 DYD1_k127_3413011_3 716544.wcw_1044 6.963e-37 147.0 COG2928@1|root,COG2928@2|Bacteria,2JFZV@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF502) CP_0247 - - - - - - - - - - - DUF502 DYD1_k127_3413011_7 716544.wcw_1042 1.73e-17 87.0 COG2927@1|root,COG2927@2|Bacteria,2JH53@204428|Chlamydiae 204428|Chlamydiae L DNA polymerase III chi subunit, HolC - - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi DYD1_k127_3413011_8 765952.PUV_10440 4.474e-09 59.0 28VZS@1|root,2ZI0Y@2|Bacteria,2JHGC@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3413011_5 331113.SNE_A09080 2.938e-21 94.0 2DNTM@1|root,32Z31@2|Bacteria,2JGEE@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3413011_4 765952.PUV_10420 1.86e-32 128.0 COG0319@1|root,COG0319@2|Bacteria,2JG8S@204428|Chlamydiae 204428|Chlamydiae J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 DYD1_k127_3413011_6 1444711.CCJF01000005_gene1255 1.316e-17 91.0 COG1253@1|root,COG1253@2|Bacteria,2JFV2@204428|Chlamydiae 204428|Chlamydiae S Domain protein tlyC_2 - - - - - - - - - - - CBS,CorC_HlyC,DUF21 DYD1_k127_3441_0 331113.SNE_A14700 2.33e-245 782.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2JFQ8@204428|Chlamydiae 204428|Chlamydiae F Together with the serine threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth pknD - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase DYD1_k127_3453147_0 264201.pc1081 3.109e-92 316.0 COG0706@1|root,COG0706@2|Bacteria,2JFUV@204428|Chlamydiae 204428|Chlamydiae U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP DYD1_k127_3453147_1 331113.SNE_A14320 1.349e-85 295.0 COG0457@1|root,COG0457@2|Bacteria,2JFDZ@204428|Chlamydiae 204428|Chlamydiae S Tetratricopeptide repeat CP_0471 - - - - - - - - - - - TPR_16,TPR_8 DYD1_k127_3454794_1 331113.SNE_B24090 8.352e-49 180.0 COG5340@1|root,COG5340@2|Bacteria 2|Bacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - AbiEi_4 DYD1_k127_3454794_0 1444712.BN1013_02291 1.237e-141 453.0 COG0017@1|root,COG2606@1|root,COG0017@2|Bacteria,COG2606@2|Bacteria,2JGS0@204428|Chlamydiae 204428|Chlamydiae J Aminoacyl-tRNA editing domain - - 6.1.1.23 ko:K09759 ko00970,map00970 M00360 R03647,R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon,tRNA_edit DYD1_k127_3455784_2 331113.SNE_A11980 9.913e-66 235.0 COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2JFIF@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413,R03084 RC00206,RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I,Shikimate_DH,Shikimate_dh_N DYD1_k127_3455784_0 1437425.CSEC_0587 5.452e-216 683.0 COG1190@1|root,COG1190@2|Bacteria,2JFIC@204428|Chlamydiae 204428|Chlamydiae J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon DYD1_k127_3455784_3 264201.pc1234 1.554e-05 50.0 28YEX@1|root,34BF2@2|Bacteria,2JH88@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3455784_1 1444711.CCJF01000005_gene1077 4.116e-107 353.0 COG0215@1|root,COG0215@2|Bacteria,2JFNB@204428|Chlamydiae 204428|Chlamydiae J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e DYD1_k127_3557741_2 331113.SNE_B24100 2.296e-26 113.0 COG2253@1|root,COG2253@2|Bacteria,2JGE7@204428|Chlamydiae 204428|Chlamydiae S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii DYD1_k127_3557741_0 1528098.NOVO_01600 1.078e-73 263.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47F3Y@766|Rickettsiales 766|Rickettsiales EGP Major facilitator proP6 - - ko:K03762 - - - - ko00000,ko02000 2.A.1.6.4 - - MFS_1,Sugar_tr DYD1_k127_3557741_1 716544.wcw_0685 8.399e-44 164.0 COG0465@1|root,COG0465@2|Bacteria,2JFFV@204428|Chlamydiae 204428|Chlamydiae D Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,Peptidase_M41 DYD1_k127_3561072_0 1437425.CSEC_1480 7.243e-25 120.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - - DYD1_k127_3561072_1 1444711.CCJF01000005_gene560 6.319e-22 107.0 COG3210@1|root,COG3210@2|Bacteria,2JGA4@204428|Chlamydiae 204428|Chlamydiae U Inverse autotransporter, beta-domain - - - - - - - - - - - - IAT_beta DYD1_k127_3561072_3 716544.wcw_0028 1.019e-10 75.0 COG0545@1|root,COG0545@2|Bacteria,2JH1W@204428|Chlamydiae 204428|Chlamydiae O FKBP-type peptidyl-prolyl cis-trans isomerase - - - - - - - - - - - - FKBP_C DYD1_k127_3561072_2 1444712.BN1013_02118 4.208e-14 86.0 2EU3I@1|root,33QAB@2|Bacteria,2JGRS@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3561711_3 331113.SNE_A18460 1.11e-59 215.0 COG1506@1|root,COG1506@2|Bacteria,2JHHT@204428|Chlamydiae 204428|Chlamydiae E peptidase - - - ko:K06889 - - - - ko00000 - - - - DYD1_k127_3561711_1 331113.SNE_A18470 2.256e-103 347.0 COG0763@1|root,COG0763@2|Bacteria,2JFD2@204428|Chlamydiae 204428|Chlamydiae M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LAB_N,LpxB DYD1_k127_3561711_4 331113.SNE_A18520 1.268e-33 134.0 COG1399@1|root,COG1399@2|Bacteria,2JGEY@204428|Chlamydiae 204428|Chlamydiae S metal-binding, possibly nucleic acid-binding protein - - - - - - - - - - - - - DYD1_k127_3561711_2 331113.SNE_A18530 6.412e-85 293.0 COG0416@1|root,COG0416@2|Bacteria,2JFZ7@204428|Chlamydiae 204428|Chlamydiae I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis DYD1_k127_3561711_0 1444711.CCJF01000005_gene979 1.029e-242 758.0 COG1530@1|root,COG1530@2|Bacteria,2JFU4@204428|Chlamydiae 204428|Chlamydiae J ribonuclease G rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD1_k127_3561711_5 331113.SNE_A18550 6.387e-26 112.0 COG0204@1|root,COG0204@2|Bacteria,2JFD3@204428|Chlamydiae 204428|Chlamydiae I Acyltransferase plsB - 2.3.1.15 ko:K00630 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_3567402_0 331113.SNE_A22850 1.083e-140 454.0 COG0022@1|root,COG0022@2|Bacteria,2JFIU@204428|Chlamydiae 2|Bacteria C Pyruvate dehydrogenase E1 acoB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_3567402_1 316058.RPB_3808 2.968e-97 329.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2U6XP@28211|Alphaproteobacteria,3K406@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD1_k127_3567402_2 1400524.KL370779_gene619 1.568e-36 149.0 COG0300@1|root,COG0300@2|Bacteria,1NYHT@1224|Proteobacteria,2UTXW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short DYD1_k127_358812_1 1125725.HMPREF1325_1319 9.827e-14 78.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.72 ko:K07319 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,ParBc DYD1_k127_358812_0 608538.HTH_0534 2.379e-18 94.0 COG0639@1|root,COG0639@2|Bacteria 2|Bacteria T phosphoprotein phosphatase activity - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos,Metallophos_2 DYD1_k127_3609141_0 264201.pc0313 6.911e-129 421.0 COG0768@1|root,COG0768@2|Bacteria,2JFH0@204428|Chlamydiae 204428|Chlamydiae M penicillin-binding protein pbp3 - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase DYD1_k127_3609141_1 765952.PUV_19630 1.618e-81 280.0 COG0275@1|root,COG0275@2|Bacteria,2JFV8@204428|Chlamydiae 204428|Chlamydiae J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 DYD1_k127_3609141_2 331113.SNE_A04940 3.611e-55 198.0 COG2001@1|root,COG2001@2|Bacteria 2|Bacteria K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ DYD1_k127_3641288_0 583355.Caka_2558 6.059e-204 644.0 COG0442@1|root,COG0442@2|Bacteria,46SE3@74201|Verrucomicrobia 74201|Verrucomicrobia J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b DYD1_k127_3641288_2 331113.SNE_A04550 2.704e-66 233.0 COG0095@1|root,COG0095@2|Bacteria,2JG15@204428|Chlamydiae 204428|Chlamydiae H Biotin/lipoate A/B protein ligase family lplA_1 - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB DYD1_k127_3641288_1 765952.PUV_04840 4.157e-77 259.0 COG0542@1|root,COG0542@2|Bacteria,2JFSM@204428|Chlamydiae 204428|Chlamydiae O ATP-dependent Clp protease ATP-binding subunit clpC - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR DYD1_k127_3641545_6 765952.PUV_22230 2.986e-06 50.0 COG0760@1|root,COG0760@2|Bacteria,2JG1Y@204428|Chlamydiae 204428|Chlamydiae O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - - - - - - - - - - Rotamase_2,SurA_N_3 DYD1_k127_3641545_3 1444711.CCJF01000004_gene1966 6.317e-65 231.0 COG0030@1|root,COG0030@2|Bacteria,2JFY7@204428|Chlamydiae 204428|Chlamydiae J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD DYD1_k127_3641545_1 1444711.CCJF01000004_gene1965 9.599e-93 317.0 COG1686@1|root,COG1686@2|Bacteria,2JFGM@204428|Chlamydiae 204428|Chlamydiae M D-alanyl-D-alanine carboxypeptidase dacC - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 DYD1_k127_3641545_4 331113.SNE_A21510 2.696e-36 142.0 2E7DZ@1|root,331X1@2|Bacteria,2JGFH@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3641545_5 545694.TREPR_2226 3.433e-17 86.0 COG2172@1|root,COG2172@2|Bacteria,2J8RN@203691|Spirochaetes 203691|Spirochaetes T Histidine kinase-like ATPase domain - - - - - - - - - - - - HATPase_c_2 DYD1_k127_3641545_2 331113.SNE_A21590 7.82e-66 235.0 COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,2JG42@204428|Chlamydiae 204428|Chlamydiae S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 DYD1_k127_3641545_0 264201.pc0389 1.83e-114 379.0 COG0587@1|root,COG0587@2|Bacteria,2JFDD@204428|Chlamydiae 204428|Chlamydiae L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity) dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP DYD1_k127_3696311_2 1306947.ARQD01000001_gene898 3.475e-19 90.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_tranf_2_4,Glycos_transf_2 DYD1_k127_3696311_0 331113.SNE_A02330 1.356e-40 168.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - Wzy_C DYD1_k127_3696311_1 1444711.CCJF01000005_gene560 3.725e-20 104.0 COG3210@1|root,COG3210@2|Bacteria,2JGA4@204428|Chlamydiae 204428|Chlamydiae U Inverse autotransporter, beta-domain - - - - - - - - - - - - IAT_beta DYD1_k127_371117_6 331113.SNE_A04420 2.339e-36 141.0 COG2271@1|root,COG2271@2|Bacteria 2|Bacteria G transmembrane transporter activity - - - - - - - - - - - - MFS_1 DYD1_k127_371117_2 331113.SNE_A04410 8.471e-92 312.0 COG3608@1|root,COG3608@2|Bacteria 2|Bacteria G succinylglutamate desuccinylase aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA DYD1_k127_371117_7 1229831.M832_07900 3.108e-08 58.0 COG0268@1|root,COG0268@2|Bacteria 2|Bacteria J rRNA binding rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p DYD1_k127_371117_8 264201.pc0130 4.623e-05 51.0 2EJ7W@1|root,33CZ2@2|Bacteria,2JGGT@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_371117_4 716544.wcw_1948 4.642e-40 159.0 COG4469@1|root,COG4469@2|Bacteria,2JG50@204428|Chlamydiae 204428|Chlamydiae S Competence protein CoiA-like family - - - ko:K06198 - - - - ko00000 - - - CoiA DYD1_k127_371117_0 331113.SNE_A23480 1.373e-294 910.0 COG0568@1|root,COG0568@2|Bacteria,2JFP5@204428|Chlamydiae 204428|Chlamydiae K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_371117_1 314282.PCNPT3_05960 3.351e-104 351.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,2QH4F@267894|Psychromonadaceae 1236|Gammaproteobacteria E Aminotransferase class I and II aspC GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iPC815.YPO1410,iSFxv_1172.SFxv_1000 Aminotran_1_2 DYD1_k127_371117_3 331113.SNE_A00850 1.497e-68 245.0 COG1792@1|root,COG1792@2|Bacteria,2JG1B@204428|Chlamydiae 204428|Chlamydiae M rod shape-determining protein MreC mreC - - - - - - - - - - - MreC DYD1_k127_371117_5 765952.PUV_00330 2.371e-39 156.0 COG1887@1|root,COG1887@2|Bacteria,2JG2U@204428|Chlamydiae 204428|Chlamydiae M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf DYD1_k127_3787443_5 716544.wcw_0640 2.254e-27 118.0 2DZIQ@1|root,32VBQ@2|Bacteria,2JGAZ@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_3787443_3 331113.SNE_A10970 3.9e-57 210.0 COG0561@1|root,COG0561@2|Bacteria,2JG2F@204428|Chlamydiae 204428|Chlamydiae S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 DYD1_k127_3787443_8 331113.SNE_A10950 6.902e-12 70.0 COG3190@1|root,COG3190@2|Bacteria,2JGJY@204428|Chlamydiae 204428|Chlamydiae N Flagellar biosynthesis protein, FliO - - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO DYD1_k127_3787443_0 765952.PUV_12530 2.022e-151 489.0 COG0001@1|root,COG0001@2|Bacteria,2JFU8@204428|Chlamydiae 204428|Chlamydiae H Glutamate-1-semialdehyde hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_3787443_1 1444711.CCJF01000005_gene1304 2.578e-102 354.0 COG0729@1|root,COG0729@2|Bacteria,2JFF4@204428|Chlamydiae 204428|Chlamydiae M Surface antigen - - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA DYD1_k127_3787443_4 457398.HMPREF0326_05626 5.396e-33 149.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,42PSZ@68525|delta/epsilon subdivisions,2WMBH@28221|Deltaproteobacteria,2M8PJ@213115|Desulfovibrionales 28221|Deltaproteobacteria S TamB, inner membrane protein subunit of TAM complex - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB DYD1_k127_3787443_7 331113.SNE_A10860 1.225e-19 94.0 COG0457@1|root,COG0457@2|Bacteria,2JGEB@204428|Chlamydiae 204428|Chlamydiae S Type III secretion lcrH_2 - - - - - - - - - - - TPR_3 DYD1_k127_3787443_2 331113.SNE_A10820 1.167e-96 323.0 COG0767@1|root,COG0767@2|Bacteria,2JFCS@204428|Chlamydiae 204428|Chlamydiae Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD1_k127_3787443_6 331113.SNE_A10810 5.082e-27 113.0 COG1127@1|root,COG1127@2|Bacteria,2JFQY@204428|Chlamydiae 204428|Chlamydiae Q ABC transporter mkl - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD1_k127_3844072_1 760192.Halhy_3634 5.728e-214 694.0 COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,4NF8P@976|Bacteroidetes,1IPIQ@117747|Sphingobacteriia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C DYD1_k127_3844072_0 716544.wcw_1776 1.427e-253 795.0 COG0445@1|root,COG0445@2|Bacteria,2JFK6@204428|Chlamydiae 204428|Chlamydiae D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc DYD1_k127_3844072_2 867900.Celly_0422 2.103e-06 59.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,1F8T1@104264|Cellulophaga 976|Bacteroidetes T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y DYD1_k127_3854876_1 1306947.ARQD01000001_gene898 1.415e-28 119.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_tranf_2_4,Glycos_transf_2 DYD1_k127_3854876_0 331113.SNE_A22770 6.8e-43 177.0 COG1215@1|root,COG1215@2|Bacteria,2JH6V@204428|Chlamydiae 204428|Chlamydiae M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_3854876_2 1306947.ARQD01000001_gene898 1.005e-25 113.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_tranf_2_4,Glycos_transf_2 DYD1_k127_3868204_0 331113.SNE_A03980 7.348e-99 332.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2JFG4@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase DYD1_k127_3868204_1 395961.Cyan7425_2889 1.161e-05 56.0 COG1232@1|root,COG1232@2|Bacteria 2|Bacteria H protoporphyrinogen oxidase activity hemG - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase,Methyltransf_11,NAD_binding_8 DYD1_k127_3873312_0 331113.SNE_A05380 3.908e-220 699.0 COG2217@1|root,COG2217@2|Bacteria,2JFGU@204428|Chlamydiae 204428|Chlamydiae P E1-E2 ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase DYD1_k127_3873312_1 331113.SNE_A05390 1.617e-75 260.0 COG1814@1|root,COG1814@2|Bacteria,2JFYP@204428|Chlamydiae 204428|Chlamydiae S VIT family - - - - - - - - - - - - VIT1 DYD1_k127_3873312_3 765952.PUV_22400 8.16e-34 135.0 COG1362@1|root,COG1362@2|Bacteria,2JFF6@204428|Chlamydiae 204428|Chlamydiae E Aminopeptidase I zinc metalloprotease (M18) apeB - 3.4.11.21 ko:K01267 - - - - ko00000,ko01000,ko01002,ko04131 - - - Peptidase_M18 DYD1_k127_3873312_2 264201.pc1490 1.305e-66 236.0 COG1362@1|root,COG1362@2|Bacteria,2JFF6@204428|Chlamydiae 204428|Chlamydiae E Aminopeptidase I zinc metalloprotease (M18) apeB - 3.4.11.21 ko:K01267 - - - - ko00000,ko01000,ko01002,ko04131 - - - Peptidase_M18 DYD1_k127_3880527_1 929556.Solca_0595 2.4e-45 168.0 COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,1IQUT@117747|Sphingobacteriia 976|Bacteroidetes V ABC transporter - - - - - - - - - - - - ABC_tran DYD1_k127_3880527_3 291112.PAU_02323 3.503e-16 88.0 2DBUF@1|root,2ZB5S@2|Bacteria,1NUFT@1224|Proteobacteria,1RYW0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - ko:K13409 ko02010,ko04626,map02010,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.110 - - Asp_protease_2 DYD1_k127_3880527_2 1089550.ATTH01000001_gene2110 1.361e-22 107.0 COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1FJEP@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes O Thioredoxin trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_3880527_0 1437425.CSEC_2056 3.128e-95 319.0 COG1171@1|root,COG1171@2|Bacteria,2JG95@204428|Chlamydiae 204428|Chlamydiae E Pyridoxal-phosphate dependent enzyme - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_391513_0 1444711.CCJF01000004_gene2315 0.0 1121.0 COG0525@1|root,COG0525@2|Bacteria,2JFDH@204428|Chlamydiae 204428|Chlamydiae J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 DYD1_k127_392783_2 1134474.O59_000792 2.356e-28 116.0 COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,1FHEP@10|Cellvibrio 1236|Gammaproteobacteria T cheY-homologous receiver domain cheY-1 - - - - - - - - - - - Response_reg DYD1_k127_392783_1 378806.STAUR_4471 2.291e-34 138.0 COG2230@1|root,COG2230@2|Bacteria,1QX5S@1224|Proteobacteria,42Y12@68525|delta/epsilon subdivisions,2WSZC@28221|Deltaproteobacteria,2YZY3@29|Myxococcales 28221|Deltaproteobacteria M cyclopropane-fatty-acyl-phospholipid synthase - - - - - - - - - - - - Methyltransf_25 DYD1_k127_392783_4 891968.Anamo_1878 1.773e-09 70.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria 2|Bacteria S peptidyl-tyrosine sulfation - - 3.4.21.107 ko:K04771,ko:K18546 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - Trypsin,Trypsin_2 DYD1_k127_392783_3 8496.XP_006266663.1 3.04e-25 120.0 KOG2458@1|root,KOG2458@2759|Eukaryota,38DMY@33154|Opisthokonta,3BC6Z@33208|Metazoa,3CV80@33213|Bilateria,4860D@7711|Chordata,48WF1@7742|Vertebrata 33208|Metazoa S glucosyltransferase activity KDELC1 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0009987,GO:0012505,GO:0016740,GO:0016757,GO:0016758,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046527,GO:0070013,GO:0071704,GO:1901135,GO:1903509 - - - - - - - - - - Filamin,Glyco_transf_90 DYD1_k127_392783_0 1285586.H131_21067 1.234e-53 200.0 COG0739@1|root,COG0739@2|Bacteria,1UX3M@1239|Firmicutes,4ICUN@91061|Bacilli,3IZYP@400634|Lysinibacillus 91061|Bacilli M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD1_k127_392783_5 985867.AEWF01000008_gene1031 0.0002033 46.0 COG0596@1|root,COG0596@2|Bacteria,1N49V@1224|Proteobacteria,2UTPS@28211|Alphaproteobacteria,47GEB@766|Rickettsiales 766|Rickettsiales S Alpha/beta hydrolase family - - - - - - - - - - - - - DYD1_k127_3937406_0 765952.PUV_27520 2.743e-298 927.0 COG0441@1|root,COG0441@2|Bacteria,2JFEP@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,ThiS,tRNA-synt_2b,tRNA_SAD DYD1_k127_3937406_1 716544.wcw_0024 3.651e-118 384.0 COG1192@1|root,COG1192@2|Bacteria,2JFK5@204428|Chlamydiae 204428|Chlamydiae D Cellulose biosynthesis protein BcsQ minD - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD1_k127_395055_0 716544.wcw_0234 1.358e-198 624.0 COG0013@1|root,COG0013@2|Bacteria,2JFU9@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD1_k127_3967229_2 331113.SNE_A22680 1.627e-51 186.0 COG0210@1|root,COG0210@2|Bacteria,2JFDE@204428|Chlamydiae 204428|Chlamydiae L DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD1_k127_3967229_1 930171.Asphe3_18330 2.145e-74 259.0 COG2230@1|root,COG2230@2|Bacteria,2IAU4@201174|Actinobacteria,1WAFZ@1268|Micrococcaceae 201174|Actinobacteria M Mycolic acid cyclopropane synthetase - - 2.1.1.95 ko:K05928 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00112 R07236,R07504,R10491,R10492 RC00003,RC01662 ko00000,ko00001,ko00002,ko01000 - - - CMAS,Methyltransf_11 DYD1_k127_3967229_3 1500893.JQNB01000001_gene1169 1.271e-07 55.0 COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,1SGD7@1236|Gammaproteobacteria,1X8RN@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1328) - - - - - - - - - - - - DUF1328 DYD1_k127_3967229_0 716544.wcw_0507 1.219e-87 297.0 COG2081@1|root,COG2081@2|Bacteria,2JFEJ@204428|Chlamydiae 204428|Chlamydiae S HI0933-like protein - - - ko:K07007 - - - - ko00000 - - - HI0933_like DYD1_k127_3976944_0 34349.G7E1F4 2.19e-29 129.0 KOG0610@1|root,KOG0610@2759|Eukaryota,38ERQ@33154|Opisthokonta,3NUP7@4751|Fungi,3UZ2T@5204|Basidiomycota,2YCY1@29000|Pucciniomycotina 4751|Fungi T Serine/Threonine protein kinases, catalytic domain NRC2 GO:0000166,GO:0000749,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005886,GO:0005937,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010033,GO:0010876,GO:0015711,GO:0015748,GO:0015914,GO:0016020,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019236,GO:0019538,GO:0023052,GO:0030427,GO:0030554,GO:0031136,GO:0031137,GO:0031139,GO:0032368,GO:0032370,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0033036,GO:0034204,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0042995,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043270,GO:0043332,GO:0043412,GO:0043900,GO:0043902,GO:0044070,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044463,GO:0044464,GO:0045332,GO:0046777,GO:0046999,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051286,GO:0051716,GO:0061024,GO:0061091,GO:0061092,GO:0065007,GO:0065008,GO:0070887,GO:0071310,GO:0071444,GO:0071702,GO:0071704,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0120025,GO:0120038,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1903793,GO:1905952,GO:1905954,GO:2000241,GO:2000243,GO:2001138,GO:2001140 - ko:K08286 - - - - ko00000,ko01000 - - - Pkinase DYD1_k127_3976944_1 1122134.KB893652_gene2428 0.000215 44.0 2DR5Z@1|root,33ABB@2|Bacteria,1NIYJ@1224|Proteobacteria,1SGQ9@1236|Gammaproteobacteria,1XQB9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - DYD1_k127_3977063_0 1122134.KB893652_gene2428 0.000215 44.0 2DR5Z@1|root,33ABB@2|Bacteria,1NIYJ@1224|Proteobacteria,1SGQ9@1236|Gammaproteobacteria,1XQB9@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - DYD1_k127_4022364_0 331113.SNE_A01370 5.339e-175 554.0 COG1053@1|root,COG1053@2|Bacteria,2JFSU@204428|Chlamydiae 204428|Chlamydiae C succinate dehydrogenase sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_4022364_1 331113.SNE_A01380 5.117e-109 357.0 COG0479@1|root,COG0479@2|Bacteria,2JFQ7@204428|Chlamydiae 204428|Chlamydiae C succinate dehydrogenase sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_17,Fer4_8 DYD1_k127_4022364_2 331113.SNE_A01510 3.414e-75 259.0 COG0095@1|root,COG0095@2|Bacteria,2JG2Z@204428|Chlamydiae 204428|Chlamydiae H Lipoate-protein ligase lplA_2 - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - - DYD1_k127_4032896_1 331113.SNE_A08250 3.93e-32 126.0 COG0236@1|root,COG0236@2|Bacteria,2JG9N@204428|Chlamydiae 204428|Chlamydiae IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD1_k127_4032896_0 1444712.BN1013_01710 5.476e-62 229.0 COG3850@1|root,COG3850@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - - - - - - - - - - - GAF,GAF_2,HAMP,HD,PAS_4,PAS_9,dCache_1 DYD1_k127_4035847_2 344747.PM8797T_22393 1.729e-17 94.0 COG0441@1|root,COG0441@2|Bacteria,2IXFR@203682|Planctomycetes 203682|Planctomycetes J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD DYD1_k127_4035847_1 1444712.BN1013_01684 1.693e-50 182.0 COG0290@1|root,COG0290@2|Bacteria,2JG36@204428|Chlamydiae 204428|Chlamydiae J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N DYD1_k127_4044973_3 1443125.Z962_08160 1.642e-08 58.0 COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia,36MUX@31979|Clostridiaceae 186801|Clostridia S Domain of unknown function (DUF378) - - - ko:K09779 - - - - ko00000 - - - DUF378 DYD1_k127_4044973_1 331113.SNE_A06880 2.652e-117 385.0 COG0697@1|root,COG0697@2|Bacteria,2JFTJ@204428|Chlamydiae 204428|Chlamydiae EG Permeases of the drug metabolite transporter (DMT) superfamily CP_1064 - - - - - - - - - - - EamA DYD1_k127_4044973_2 1444711.CCJF01000005_gene1816 2.635e-56 203.0 COG1738@1|root,COG1738@2|Bacteria,2JG7K@204428|Chlamydiae 204428|Chlamydiae S Putative vitamin uptake transporter CP_0548 - - ko:K09125 - - - - ko00000 - - - Vut_1 DYD1_k127_4044973_0 331113.SNE_A06900 1.024e-192 606.0 COG0343@1|root,COG0343@2|Bacteria,2JFWK@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT DYD1_k127_4046538_0 1444711.CCJF01000005_gene361 6.155e-31 123.0 COG0659@1|root,COG0659@2|Bacteria,2JFQW@204428|Chlamydiae 204428|Chlamydiae P Sulfate transporter family ychM - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp DYD1_k127_4059354_3 331113.SNE_A01240 2.214e-22 103.0 COG2885@1|root,COG2885@2|Bacteria,2JG4H@204428|Chlamydiae 204428|Chlamydiae M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD1_k127_4059354_0 1444711.CCJF01000005_gene213 3.608e-110 370.0 COG0823@1|root,COG0823@2|Bacteria,2JFJD@204428|Chlamydiae 204428|Chlamydiae U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 DYD1_k127_4059354_4 331113.SNE_A01260 1.907e-11 73.0 COG0810@1|root,COG0810@2|Bacteria,2JGFW@204428|Chlamydiae 204428|Chlamydiae M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins tolA - - ko:K03646,ko:K03832 - - - - ko00000,ko02000 2.C.1.1,2.C.1.2 - - - DYD1_k127_4059354_2 331113.SNE_A01270 8.142e-28 118.0 COG0848@1|root,COG0848@2|Bacteria,2JGAW@204428|Chlamydiae 204428|Chlamydiae U Biopolymer transport protein ExbD/TolR tolR - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD DYD1_k127_4059354_1 1444712.BN1013_00324 1.314e-36 141.0 COG0811@1|root,COG0811@2|Bacteria,2JFXS@204428|Chlamydiae 204428|Chlamydiae U MotA TolQ ExbB proton channel family protein exbB - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB DYD1_k127_4109880_0 331113.SNE_A06380 2.371e-73 261.0 COG4313@1|root,COG4313@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Phenol_MetA_deg DYD1_k127_4112222_2 536232.CLM_1965 4.207e-08 64.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,36DDB@31979|Clostridiaceae 186801|Clostridia F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin DYD1_k127_4112222_0 331113.SNE_A21730 5.642e-53 197.0 COG0204@1|root,COG0204@2|Bacteria,2JG8Z@204428|Chlamydiae 204428|Chlamydiae I Acyltransferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_4112222_1 765952.PUV_25290 2.057e-32 128.0 COG3118@1|root,COG3118@2|Bacteria,2JG8T@204428|Chlamydiae 204428|Chlamydiae O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_4112222_3 207559.Dde_3739 6.125e-05 48.0 2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,42XZ1@68525|delta/epsilon subdivisions,2WTGJ@28221|Deltaproteobacteria,2ME5V@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 DYD1_k127_4132786_2 1444711.CCJF01000005_gene1754 1.303e-15 77.0 COG0821@1|root,COG0821@2|Bacteria,2JFII@204428|Chlamydiae 204428|Chlamydiae I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE DYD1_k127_4132786_0 765952.PUV_10060 0.0 1235.0 COG0495@1|root,COG0495@2|Bacteria,2JFVD@204428|Chlamydiae 204428|Chlamydiae J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2,tRNA-synt_1g DYD1_k127_4132786_1 331113.SNE_A12530 5.728e-83 289.0 COG1519@1|root,COG1519@2|Bacteria,2JFFN@204428|Chlamydiae 204428|Chlamydiae M Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of three 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide- 1,4'-bisphosphate precursor of lipid A. Thus generates the genus- specific LPS epitope of Chlamydia, composed of the trisaccharide alpha-Kdo-(2- 8)-alpha-Kdo-(2- 4)-alpha-Kdo waaA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N DYD1_k127_4147420_0 331113.SNE_A04190 1.893e-293 913.0 COG0021@1|root,COG0021@2|Bacteria,2JFFT@204428|Chlamydiae 204428|Chlamydiae G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N DYD1_k127_4147420_2 765952.PUV_05950 1.539e-83 286.0 COG0407@1|root,COG0407@2|Bacteria,2JFYX@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D DYD1_k127_4147420_1 1229831.M832_06470 3.325e-116 388.0 COG0635@1|root,COG0635@2|Bacteria 2|Bacteria H coproporphyrinogen oxidase activity hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R06895 RC00884 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3134,iZ_1308.Z5403 HemN_C,Radical_SAM DYD1_k127_4147420_3 331113.SNE_A04230 9.463e-69 247.0 COG1232@1|root,COG1232@2|Bacteria,2JFUM@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemG - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase DYD1_k127_4147540_3 716544.wcw_0501 2.598e-64 230.0 2CD1E@1|root,2ZB0F@2|Bacteria,2JFU1@204428|Chlamydiae 204428|Chlamydiae S Bacterial SH3 domain homologues CP_0670 - - - - - - - - - - - SH3_3 DYD1_k127_4147540_0 331113.SNE_A16480 7.389e-105 346.0 COG2833@1|root,COG2833@2|Bacteria,2JFXC@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF455) - - - - - - - - - - - - DUF455 DYD1_k127_4147540_1 331113.SNE_A16520 1.164e-100 338.0 COG1322@1|root,COG1322@2|Bacteria,2JFJ6@204428|Chlamydiae 204428|Chlamydiae S DNA recombination protein RmuC homolog rmuC - - ko:K09760 - - - - ko00000 - - - RmuC DYD1_k127_4147540_2 331113.SNE_A16540 1.344e-90 306.0 COG1183@1|root,COG1183@2|Bacteria,2JFMU@204428|Chlamydiae 204428|Chlamydiae I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD1_k127_4152091_2 716544.wcw_1567 8.967e-61 214.0 COG0648@1|root,COG0648@2|Bacteria,2JFHU@204428|Chlamydiae 204428|Chlamydiae L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 DYD1_k127_4152091_0 313628.LNTAR_23369 1.502e-174 557.0 COG0017@1|root,COG0017@2|Bacteria 2|Bacteria J Asparaginyl-tRNA synthetase asnS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSDY_1059.SDY_2327 tRNA-synt_2,tRNA_anti-codon DYD1_k127_4152091_3 1444711.CCJF01000005_gene828 3.975e-60 221.0 COG0373@1|root,COG0373@2|Bacteria,2JFNX@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,Shikimate_DH DYD1_k127_4152091_4 470.IX87_21610 0.0004557 49.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,3NK97@468|Moraxellaceae 1236|Gammaproteobacteria S Regulatory protein recX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX DYD1_k127_4152091_1 1444711.CCJF01000005_gene836 1.002e-101 338.0 COG0564@1|root,COG0564@2|Bacteria,2JFIY@204428|Chlamydiae 204428|Chlamydiae J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_4167676_0 331113.SNE_A14530 2.61e-27 117.0 2EAAF@1|root,334ES@2|Bacteria,2JGCU@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4171152_2 331113.SNE_A17250 8.837e-57 209.0 COG0707@1|root,COG0707@2|Bacteria,2JFEE@204428|Chlamydiae 204428|Chlamydiae M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 DYD1_k127_4171152_0 1444712.BN1013_00909 6.008e-110 366.0 COG0772@1|root,COG0772@2|Bacteria,2JFCC@204428|Chlamydiae 204428|Chlamydiae D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE DYD1_k127_4171152_3 716544.wcw_1388 1.705e-31 132.0 COG1388@1|root,COG1388@2|Bacteria,2JG8Q@204428|Chlamydiae 204428|Chlamydiae M Lysin motif nlpD - - - - - - - - - - - LysM DYD1_k127_4171152_1 1444711.CCJF01000005_gene1053 8.52e-99 336.0 COG0771@1|root,COG0771@2|Bacteria,2JFMY@204428|Chlamydiae 204428|Chlamydiae M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M DYD1_k127_4177517_1 1121904.ARBP01000001_gene5485 2.382e-59 210.0 28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,47MJR@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_4177517_2 1237149.C900_01784 1.575e-23 102.0 2EDEU@1|root,337B5@2|Bacteria,4NVH5@976|Bacteroidetes,47SHQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_4177517_0 1237149.C900_01781 1.046e-88 296.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - DYD1_k127_4181537_2 4096.XP_009763750.1 7.883e-25 118.0 COG2230@1|root,2QSMW@2759|Eukaryota,37NYG@33090|Viridiplantae,3GBIW@35493|Streptophyta,44I9S@71274|asterids 35493|Streptophyta M Flavin containing amine oxidoreductase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - Amino_oxidase,CMAS,NAD_binding_8 DYD1_k127_4181537_0 794903.OPIT5_13610 5.358e-69 254.0 COG2831@1|root,COG2831@2|Bacteria 2|Bacteria U hemolysin activation secretion protein - - - - - - - - - - - - POTRA_2,ShlB DYD1_k127_4181537_1 570967.JMLV01000006_gene340 2.346e-38 156.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria,2JS66@204441|Rhodospirillales 204441|Rhodospirillales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD1_k127_4181537_3 331113.SNE_A02450 6.875e-17 82.0 COG0300@1|root,COG1211@1|root,COG0300@2|Bacteria,COG1211@2|Bacteria,2JG5T@204428|Chlamydiae 2|Bacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 1.1.1.405,2.7.7.40,2.7.7.60,4.6.1.12 ko:K00991,ko:K12506,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633,R05637 RC00002,RC00089,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,adh_short DYD1_k127_4246599_8 3218.PP1S22_124V6.1 2.026e-14 78.0 COG0297@1|root,2QQTU@2759|Eukaryota,37R9T@33090|Viridiplantae,3GG40@35493|Streptophyta 35493|Streptophyta O Belongs to the glycosyltransferase 1 family. Bacterial plant glycogen synthase subfamily - GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005982,GO:0006073,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009507,GO:0009536,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019252,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 DYD1_k127_4246599_4 716544.wcw_0815 4.324e-48 179.0 COG1825@1|root,COG1825@2|Bacteria,2JG0I@204428|Chlamydiae 204428|Chlamydiae J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C DYD1_k127_4246599_3 331113.SNE_A18090 4.334e-54 196.0 COG0193@1|root,COG0193@2|Bacteria,2JG54@204428|Chlamydiae 204428|Chlamydiae J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro DYD1_k127_4246599_5 765952.PUV_15890 2.181e-45 167.0 COG0360@1|root,COG0360@2|Bacteria,2JG6K@204428|Chlamydiae 204428|Chlamydiae J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 DYD1_k127_4246599_7 1437425.CSEC_1021 2.49e-22 100.0 COG0238@1|root,COG0238@2|Bacteria,2JGBA@204428|Chlamydiae 204428|Chlamydiae J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 DYD1_k127_4246599_6 264201.pc1590 6.766e-42 160.0 COG0359@1|root,COG0359@2|Bacteria,2JG41@204428|Chlamydiae 204428|Chlamydiae J binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N DYD1_k127_4246599_2 331113.SNE_A18050 4.206e-67 238.0 COG1947@1|root,COG1947@2|Bacteria,2JFYM@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE - 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_N DYD1_k127_4246599_0 765952.PUV_13600 2.075e-126 412.0 COG0451@1|root,COG0451@2|Bacteria,2JFMJ@204428|Chlamydiae 204428|Chlamydiae GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose hldD - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase DYD1_k127_4246599_1 706587.Desti_1537 3.334e-67 243.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,2MQGF@213462|Syntrophobacterales 28221|Deltaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF987.Gmet_0922 CTP_transf_like,PfkB DYD1_k127_4269264_3 331113.SNE_A10100 2.596e-22 105.0 COG3083@1|root,COG3083@2|Bacteria 2|Bacteria S sulfuric ester hydrolase activity yejM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07014 - - - - ko00000 - - - DUF3413,Sulfatase DYD1_k127_4269264_1 264201.pc0329 7.198e-61 217.0 COG0637@1|root,COG0637@2|Bacteria,2JG4C@204428|Chlamydiae 204428|Chlamydiae S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 DYD1_k127_4269264_0 716544.wcw_0374 1.408e-80 276.0 COG0101@1|root,COG0101@2|Bacteria,2JFJC@204428|Chlamydiae 204428|Chlamydiae J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA1 - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 DYD1_k127_4269264_2 3067.XP_002958218.1 1.31e-50 187.0 COG1211@1|root,2QUUE@2759|Eukaryota,37JBI@33090|Viridiplantae,34HD7@3041|Chlorophyta 3041|Chlorophyta H 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CMS - 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD DYD1_k127_4283804_4 96561.Dole_2486 1.542e-12 72.0 COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2MI50@213118|Desulfobacterales 28221|Deltaproteobacteria F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA DYD1_k127_4283804_0 1444711.CCJF01000005_gene259 2.186e-70 248.0 COG0564@1|root,COG0564@2|Bacteria,2JG28@204428|Chlamydiae 204428|Chlamydiae J RNA pseudouridylate synthase - - 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 DYD1_k127_4283804_1 716544.wcw_1461 9.163e-39 148.0 COG1186@1|root,COG1186@2|Bacteria,2JH63@204428|Chlamydiae 204428|Chlamydiae J RF-1 domain prfA3 - - - - - - - - - - - RF-1 DYD1_k127_4283804_2 331113.SNE_A10380 2.481e-25 111.0 COG1661@1|root,COG1661@2|Bacteria 2|Bacteria O DNA-binding protein with PD1-like DNA-binding motif - - - ko:K06934 - - - - ko00000 - - - DUF296 DYD1_k127_4283804_3 497964.CfE428DRAFT_6673 4.781e-20 94.0 COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM RNP-1 like RNA-binding protein - - - - - - - - - - - - RRM_1 DYD1_k127_4283804_5 716544.wcw_0197 2.913e-10 61.0 COG2050@1|root,COG2050@2|Bacteria,2JG6F@204428|Chlamydiae 204428|Chlamydiae Q protein, possibly involved in aromatic compounds catabolism - - - - - - - - - - - - 4HBT DYD1_k127_4301066_2 765952.PUV_04690 0.0008989 42.0 COG0571@1|root,COG0571@2|Bacteria,2JFR9@204428|Chlamydiae 204428|Chlamydiae J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm DYD1_k127_4301066_0 264201.pc0273 1.29e-192 610.0 COG1066@1|root,COG1066@2|Bacteria,2JFUU@204428|Chlamydiae 204428|Chlamydiae L DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C DYD1_k127_4301066_1 716544.wcw_0250 3.311e-17 83.0 COG0181@1|root,COG1587@1|root,COG0181@2|Bacteria,COG1587@2|Bacteria,2JFY0@204428|Chlamydiae 204428|Chlamydiae H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - HEM4,Porphobil_deam DYD1_k127_4304905_0 1444711.CCJF01000004_gene2039 3.219e-142 456.0 COG1234@1|root,COG1234@2|Bacteria,2JFIS@204428|Chlamydiae 204428|Chlamydiae J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 DYD1_k127_4304905_1 1437425.CSEC_0680 5.955e-76 269.0 COG0705@1|root,COG0705@2|Bacteria,2JFTB@204428|Chlamydiae 204428|Chlamydiae S Rhomboid family glpG - - ko:K02441 - - - - ko00000 - - - Rhomboid,Rhomboid_N DYD1_k127_4304905_2 1444711.CCJF01000004_gene2041 7.462e-29 117.0 COG0615@1|root,COG0615@2|Bacteria,2JG3S@204428|Chlamydiae 204428|Chlamydiae IM Cytidylyltransferase-like hldC - - - - - - - - - - - CTP_transf_like DYD1_k127_4331851_0 331113.SNE_A05030 3.717e-195 614.0 COG0362@1|root,COG0362@2|Bacteria,2JFPS@204428|Chlamydiae 204428|Chlamydiae G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 DYD1_k127_4331851_1 331113.SNE_A05000 1.359e-54 199.0 COG0860@1|root,COG0860@2|Bacteria,2JG43@204428|Chlamydiae 204428|Chlamydiae M N-acetylmuramoyl-L-alanine amidase amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 DYD1_k127_4331851_2 1122947.FR7_3216 3.674e-12 69.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H2VD@909932|Negativicutes 909932|Negativicutes M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.10,6.3.2.13 ko:K01928,ko:K15792 ko00300,ko00550,map00300,map00550 - R02788,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_4338007_1 716544.wcw_0423 2.361e-48 178.0 COG0552@1|root,COG0552@2|Bacteria,2JFD8@204428|Chlamydiae 204428|Chlamydiae D Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N DYD1_k127_4338007_0 331113.SNE_A15010 3.553e-138 445.0 COG0176@1|root,COG0176@2|Bacteria,2JFM5@204428|Chlamydiae 204428|Chlamydiae F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA DYD1_k127_4338007_3 1444711.CCJF01000004_gene2270 0.0003759 49.0 2EG4Z@1|root,339WW@2|Bacteria,2JGJF@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4338007_2 765952.PUV_23640 1.464e-24 111.0 2DMFE@1|root,32R57@2|Bacteria,2JG5R@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4342858_2 1437425.CSEC_2019 1.463e-252 788.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2JGR0@204428|Chlamydiae 204428|Chlamydiae H Pyruvate phosphate dikinase, PEP/pyruvate binding domain ppsA - 2.7.9.1,2.7.9.2 ko:K01006,ko:K01007 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173,M00374 R00199,R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N DYD1_k127_4342858_3 1396141.BATP01000059_gene2437 1.388e-106 355.0 COG1052@1|root,COG1052@2|Bacteria,46SGM@74201|Verrucomicrobia,2ITY0@203494|Verrucomicrobiae 203494|Verrucomicrobiae CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_4342858_1 237368.SCABRO_03039 1.094e-279 881.0 COG0188@1|root,COG0188@2|Bacteria,2IY0U@203682|Planctomycetes 203682|Planctomycetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD1_k127_4342858_0 1444711.CCJF01000005_gene1235 0.0 1187.0 COG0187@1|root,COG0187@2|Bacteria,2JFF2@204428|Chlamydiae 204428|Chlamydiae L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD1_k127_4342858_4 1444711.CCJF01000005_gene1234 1.232e-20 95.0 COG5512@1|root,COG5512@2|Bacteria,2JGEC@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 DYD1_k127_4370384_1 1444712.BN1013_00178 7.95e-140 458.0 COG0013@1|root,COG0013@2|Bacteria,2JFU9@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD1_k127_4370384_0 331113.SNE_A04130 1.028e-170 553.0 COG1197@1|root,COG1197@2|Bacteria,2JFGI@204428|Chlamydiae 204428|Chlamydiae L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF DYD1_k127_4384498_0 926550.CLDAP_10480 2.795e-130 420.0 COG0399@1|root,COG0399@2|Bacteria 2|Bacteria E UDP-4-amino-4-deoxy-L-arabinose aminotransferase rfbH - 1.17.1.1,4.2.1.164 ko:K12452,ko:K13328 ko00520,ko00523,ko01130,map00520,map00523,map01130 M00802 R03391,R03392,R08930 RC00230,RC00704 ko00000,ko00001,ko00002,ko01000 - - - DegT_DnrJ_EryC1 DYD1_k127_4384498_1 1121382.JQKG01000010_gene4636 6.159e-119 391.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity yfnG - 4.2.1.45 ko:K01709 ko00520,map00520 - R02426 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd DYD1_k127_4401788_0 4899.EPX71989 2.217e-09 63.0 KOG0590@1|root,KOG0590@2759|Eukaryota,39H3B@33154|Opisthokonta,3NVGV@4751|Fungi,3QJKZ@4890|Ascomycota,3MBSC@451866|Taphrinomycotina 4751|Fungi D HAL protein kinase NPR1 GO:0000122,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006873,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009373,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0012505,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019216,GO:0019219,GO:0019222,GO:0019236,GO:0019538,GO:0019725,GO:0022898,GO:0023052,GO:0030100,GO:0030554,GO:0031135,GO:0031137,GO:0031138,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032409,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0034762,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043901,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045806,GO:0045892,GO:0045934,GO:0045996,GO:0046019,GO:0046020,GO:0046890,GO:0046999,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055082,GO:0060255,GO:0060627,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0071944,GO:0080090,GO:0090153,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1905038,GO:2000112,GO:2000113,GO:2000241,GO:2000242,GO:2001141 - - - - - - - - - - Pkinase DYD1_k127_4404749_0 264201.pc0749 2.38e-198 628.0 COG4789@1|root,COG4789@2|Bacteria,2JFH4@204428|Chlamydiae 204428|Chlamydiae U Type III secretion inner membrane protein SctV sctV - - ko:K03230 ko03070,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 - - FHIPEP DYD1_k127_4404749_1 1444711.CCJF01000005_gene1746 1.53e-102 345.0 COG1377@1|root,COG1377@2|Bacteria,2JFD1@204428|Chlamydiae 204428|Chlamydiae U Type III secretion sctU - - ko:K03229 ko03070,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 - - Bac_export_2 DYD1_k127_4404749_4 676032.FN3523_1133 9.853e-07 51.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,45ZWW@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N DYD1_k127_4404749_3 1289135.A966_02073 3.438e-15 78.0 COG0787@1|root,COG0787@2|Bacteria,2J5JY@203691|Spirochaetes 203691|Spirochaetes M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N DYD1_k127_4421816_0 316058.RPB_3802 3.183e-111 373.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,3JR67@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Acetolactate synthase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_4421816_1 1380394.JADL01000001_gene2770 1.147e-81 276.0 COG0279@1|root,COG0279@2|Bacteria,1PW0E@1224|Proteobacteria,2U850@28211|Alphaproteobacteria 28211|Alphaproteobacteria G SIS domain - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 DYD1_k127_4421816_2 497964.CfE428DRAFT_2552 7.54e-52 189.0 COG0241@1|root,COG0241@2|Bacteria,46T3Q@74201|Verrucomicrobia 74201|Verrucomicrobia E hydrolase, HAD-superfamily, subfamily IIIA - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - HAD_2,Hydrolase_like DYD1_k127_4421816_3 1321778.HMPREF1982_00182 9.793e-06 48.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes 1239|Firmicutes H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA DYD1_k127_4426972_0 1353529.M899_1347 7.066e-59 226.0 COG0642@1|root,COG4251@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2MTI7@213481|Bdellovibrionales,2WIR4@28221|Deltaproteobacteria 213481|Bdellovibrionales T Histidine kinase A domain protein - - - - - - - - - - - - CHASE,HATPase_c,HisKA,PAS_3,Response_reg DYD1_k127_4426972_1 716544.wcw_1137 1.116e-22 102.0 COG0745@1|root,COG0745@2|Bacteria,2JH9M@204428|Chlamydiae 204428|Chlamydiae T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg DYD1_k127_4426972_2 765913.ThidrDRAFT_1067 6.302e-12 78.0 COG0642@1|root,COG0784@1|root,COG3614@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3614@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1WVYT@135613|Chromatiales 135613|Chromatiales T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg DYD1_k127_4426972_3 1297570.MESS4_830024 1.077e-08 68.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_10,TPR_11,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8 DYD1_k127_4464758_6 1410650.JHWL01000023_gene2318 7.211e-06 52.0 COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,4BW25@830|Butyrivibrio 186801|Clostridia P TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD1_k127_4464758_3 1444711.CCJF01000005_gene318 8.774e-147 482.0 COG0168@1|root,COG0168@2|Bacteria,2JFTF@204428|Chlamydiae 204428|Chlamydiae P Trk-type K transport systems, membrane components - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH DYD1_k127_4464758_4 264201.pc0027 2.284e-48 182.0 COG2264@1|root,COG2264@2|Bacteria,2JGAK@204428|Chlamydiae 204428|Chlamydiae J Ribosomal protein L11 methyltransferase (PrmA) prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA DYD1_k127_4464758_1 716544.wcw_1849 3.464e-246 771.0 COG0459@1|root,COG0459@2|Bacteria,2JFPP@204428|Chlamydiae 204428|Chlamydiae O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL2 - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD1_k127_4464758_5 264201.pc0031 4.244e-29 119.0 COG0234@1|root,COG0234@2|Bacteria,2JG9S@204428|Chlamydiae 204428|Chlamydiae O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD1_k127_4464758_2 331113.SNE_A22610 7.245e-168 536.0 COG3876@1|root,COG3876@2|Bacteria,2JFQB@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF1343) ybbC - - - - - - - - - - - DUF1343 DYD1_k127_4464758_0 331113.SNE_A22620 7.006e-288 900.0 COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,2JFQE@204428|Chlamydiae 204428|Chlamydiae CE Belongs to the aldehyde dehydrogenase family putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh DYD1_k127_4490555_0 331113.SNE_A01990 3.403e-121 398.0 COG1249@1|root,COG1249@2|Bacteria,2JFIX@204428|Chlamydiae 204428|Chlamydiae C The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim DYD1_k127_4490555_2 716544.wcw_0104 1.119e-12 74.0 2E888@1|root,332MB@2|Bacteria,2JGF8@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4490555_1 765869.BDW_09435 8.676e-15 75.0 COG1055@1|root,COG1055@2|Bacteria,1N68M@1224|Proteobacteria,42PD9@68525|delta/epsilon subdivisions,2MTG9@213481|Bdellovibrionales,2WKRV@28221|Deltaproteobacteria 213481|Bdellovibrionales P Putative Na+/H+ antiporter - - - - - - - - - - - - Na_H_antiport_3 DYD1_k127_4513871_0 1444711.CCJF01000005_gene766 6.095e-117 394.0 COG0659@1|root,COG0659@2|Bacteria,2JFMP@204428|Chlamydiae 204428|Chlamydiae P Sulfate permease family - - - - - - - - - - - - STAS,Sulfate_transp DYD1_k127_4516704_3 652103.Rpdx1_1421 2.204e-55 200.0 2F4HQ@1|root,33X7J@2|Bacteria 2|Bacteria S Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 DYD1_k127_4516704_0 316055.RPE_1516 7.6e-159 507.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,3JRQ2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46,4.2.1.76,5.1.3.2 ko:K01710,ko:K01784,ko:K12450 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R00293,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD1_k127_4516704_2 1380394.JADL01000001_gene2741 4.217e-66 236.0 COG0451@1|root,COG0451@2|Bacteria,1RC9U@1224|Proteobacteria,2UGSH@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM RmlD substrate binding domain - - - - - - - - - - - - Epimerase DYD1_k127_4516704_1 1380394.JADL01000001_gene2742 2.328e-80 275.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2JPVB@204441|Rhodospirillales 204441|Rhodospirillales M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - - - - - - - - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_4535086_6 716544.wcw_1580 1.727e-06 54.0 COG2604@1|root,COG2604@2|Bacteria,2JFK8@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function DUF115 - - - - - - - - - - - - MAF_flag10 DYD1_k127_4535086_5 765952.PUV_25720 2.72e-11 68.0 COG2849@1|root,COG2849@2|Bacteria,2JGQS@204428|Chlamydiae 204428|Chlamydiae S MORN repeat variant - - - - - - - - - - - - MORN_2 DYD1_k127_4535086_1 331113.SNE_A19000 3.109e-33 143.0 COG2604@1|root,COG2604@2|Bacteria,2JFK8@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function DUF115 - - - - - - - - - - - - MAF_flag10 DYD1_k127_4535086_4 1121129.KB903367_gene2747 4.072e-13 74.0 COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,2G3EH@200643|Bacteroidia,22Y4B@171551|Porphyromonadaceae 976|Bacteroidetes V Type I restriction enzyme R protein N terminus (HSDR_N) - - - - - - - - - - - - HSDR_N_2 DYD1_k127_4535086_0 716544.wcw_1585 2.286e-49 183.0 COG1544@1|root,COG1544@2|Bacteria,2JFY2@204428|Chlamydiae 204428|Chlamydiae J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE DYD1_k127_4535086_2 331113.SNE_A19090 9.755e-19 93.0 COG1381@1|root,COG1381@2|Bacteria,2JG9R@204428|Chlamydiae 204428|Chlamydiae L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N DYD1_k127_4535086_3 1157490.EL26_03800 2.238e-18 87.0 COG1164@1|root,COG1164@2|Bacteria,1U8XY@1239|Firmicutes,4HEV8@91061|Bacilli 91061|Bacilli E Peptidase M3A and M3B thimet oligopeptidase F - - - - - - - - - - - - Peptidase_M2,Peptidase_M3 DYD1_k127_4546182_1 765952.PUV_12630 3.814e-87 300.0 COG0859@1|root,COG0859@2|Bacteria,2JFJF@204428|Chlamydiae 204428|Chlamydiae M Glycosyltransferase family 9 (heptosyltransferase) waaC - - ko:K02841 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_4546182_0 331113.SNE_A08550 1.752e-118 395.0 COG3104@1|root,COG3104@2|Bacteria 2|Bacteria E oligopeptide transport - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 DYD1_k127_4546182_2 1444712.BN1013_01688 7.171e-32 129.0 COG0564@1|root,COG0564@2|Bacteria,2JG7S@204428|Chlamydiae 204428|Chlamydiae J Pseudouridine synthase rluC - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 DYD1_k127_4568876_3 264201.pc1082 4.332e-37 145.0 COG0593@1|root,COG0593@2|Bacteria,2JFG5@204428|Chlamydiae 204428|Chlamydiae L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA1 - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N DYD1_k127_4568876_4 529818.AMSG_07184T0 5.212e-21 107.0 KOG0598@1|root,KOG0598@2759|Eukaryota 2759|Eukaryota H protein serine/threonine kinase activity - - 2.7.11.1 ko:K08282,ko:K13303 ko04068,ko04151,map04068,map04151 - - - ko00000,ko00001,ko01000,ko01001 - - - Pkinase DYD1_k127_4568876_1 331113.SNE_A14370 9.998e-74 251.0 28KCR@1|root,2Z9ZJ@2|Bacteria,2JFPG@204428|Chlamydiae 204428|Chlamydiae S Tir chaperone protein (CesT) family CP_0368 - - - - - - - - - - - CesT DYD1_k127_4568876_0 264201.pc1106 6.976e-207 661.0 COG1523@1|root,COG1523@2|Bacteria,2JFKM@204428|Chlamydiae 204428|Chlamydiae G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 DYD1_k127_4568876_2 331113.SNE_A14400 6.488e-39 154.0 2919I@1|root,2ZNWM@2|Bacteria,2JHFF@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4595876_3 243164.DET0206 3.337e-28 117.0 COG2605@1|root,COG2605@2|Bacteria,2G5TF@200795|Chloroflexi 200795|Chloroflexi S PFAM GHMP kinase - - 2.7.1.168 ko:K07031 ko00540,map00540 - R09770 RC00002,RC00078 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD1_k127_4595876_2 1485543.JMME01000001_gene1350 5.317e-44 168.0 COG1208@1|root,COG1208@2|Bacteria,1V69F@1239|Firmicutes,4H916@909932|Negativicutes 909932|Negativicutes JM Nucleotidyl transferase - - - - - - - - - - - - NTP_transferase DYD1_k127_4595876_0 192222.Cj1427c 7.459e-130 421.0 COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2YNIP@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M NAD dependent epimerase dehydratase family - - 5.1.3.25 ko:K17947 ko00523,ko01130,map00523,map01130 - R10279 RC00289 ko00000,ko00001,ko01000 - - - Epimerase DYD1_k127_4595876_1 258594.RPA3918 1.095e-59 216.0 COG0300@1|root,COG0300@2|Bacteria,1NYHT@1224|Proteobacteria,2UTXW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short DYD1_k127_4600936_2 331113.SNE_A14410 3.387e-26 113.0 COG1266@1|root,COG1266@2|Bacteria,2JGC1@204428|Chlamydiae 204428|Chlamydiae S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi DYD1_k127_4600936_1 331113.SNE_A14430 1.258e-62 225.0 COG0631@1|root,COG0631@2|Bacteria,2JG4D@204428|Chlamydiae 204428|Chlamydiae T Serine threonine protein phosphatase prpC - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 DYD1_k127_4600936_0 331113.SNE_A14440 5.404e-113 376.0 COG1104@1|root,COG1104@2|Bacteria,2JFR6@204428|Chlamydiae 204428|Chlamydiae E Aminotransferase class-V nifS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 DYD1_k127_4602970_1 264201.pc0443 1.322e-82 279.0 COG0740@1|root,COG0740@2|Bacteria,2JFZF@204428|Chlamydiae 204428|Chlamydiae O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP1 - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease DYD1_k127_4602970_2 1121904.ARBP01000007_gene3021 6.895e-53 195.0 COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia 976|Bacteroidetes E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase DYD1_k127_4602970_0 264201.pc1486 8.055e-134 432.0 COG0686@1|root,COG0686@2|Bacteria,2JFCH@204428|Chlamydiae 204428|Chlamydiae C Alanine dehydrogenase/PNT, N-terminal domain ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N DYD1_k127_4619279_0 468059.AUHA01000002_gene1245 8.958e-154 497.0 COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1IQ03@117747|Sphingobacteriia 976|Bacteroidetes GM Protein of unknown function (DUF2867) - - - - - - - - - - - - DUF2867,Epimerase,NAD_binding_10 DYD1_k127_4619279_1 331113.SNE_A00390 1.933e-124 411.0 2BADF@1|root,323TX@2|Bacteria,2JG8B@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4645558_0 1282362.AEAC466_21250 5.545e-39 167.0 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2TTVB@28211|Alphaproteobacteria,2KI7D@204458|Caulobacterales 204458|Caulobacterales U haemagglutination activity domain - - - - - - - - - - - - ESPR,Haemagg_act DYD1_k127_4655603_0 497965.Cyan7822_2527 3.433e-73 275.0 COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1GHFQ@1117|Cyanobacteria,3KKTE@43988|Cyanothece 1117|Cyanobacteria T histidine kinase A domain protein - - - - - - - - - - - - GAF,HAMP,HATPase_c,HisKA,PAS_2,PAS_3,PAS_9,PHY,Response_reg,dCache_1 DYD1_k127_4663652_4 264201.pc1983 1.13e-31 128.0 COG0176@1|root,COG0176@2|Bacteria,2JG51@204428|Chlamydiae 204428|Chlamydiae H Transaldolase/Fructose-6-phosphate aldolase - - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA DYD1_k127_4663652_3 1123514.KB905899_gene1037 3.928e-36 145.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,462GE@72273|Thiotrichales 72273|Thiotrichales U MarC family integral membrane protein - - - - - - - - - - - - MarC DYD1_k127_4663652_2 331113.SNE_A11040 4.731e-48 175.0 COG0229@1|root,COG0229@2|Bacteria,2JGD0@204428|Chlamydiae 204428|Chlamydiae C SelR domain msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR DYD1_k127_4663652_5 1444711.CCJF01000004_gene2326 1.255e-09 63.0 28QB9@1|root,2ZCTV@2|Bacteria,2JHFB@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4663652_0 331113.SNE_A10010 4.951e-88 303.0 COG3468@1|root,COG3468@2|Bacteria 2|Bacteria MU cell adhesion - - - ko:K02024 - - - - ko00000,ko02000 1.B.3.1.1 - - Autotransporter,NIDO,OMP_b-brl,VPEP DYD1_k127_4663652_1 1047013.AQSP01000142_gene222 3.798e-52 194.0 COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria 2|Bacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471 DYD1_k127_4679032_0 1437425.CSEC_1523 2.538e-70 242.0 COG0605@1|root,COG0605@2|Bacteria,2JG4M@204428|Chlamydiae 204428|Chlamydiae C Iron/manganese superoxide dismutases, C-terminal domain chrC - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C DYD1_k127_4679032_1 529709.PYCH_18500 4.572e-69 245.0 COG0009@1|root,arCOG01952@2157|Archaea,2XVGC@28890|Euryarchaeota,243AA@183968|Thermococci 183968|Thermococci J required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC DYD1_k127_4679032_2 666684.AfiDRAFT_1773 2.786e-08 55.0 COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,2TRF3@28211|Alphaproteobacteria,3JRDS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Squalene-hopene cyclase C-terminal domain shc - 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N DYD1_k127_4685056_1 1313421.JHBV01000033_gene2348 1.017e-36 150.0 COG1577@1|root,COG1577@2|Bacteria,4NDYJ@976|Bacteroidetes 976|Bacteroidetes I mevalonate kinase mvaK - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD1_k127_4685056_0 1122179.KB890436_gene1281 6.236e-45 169.0 COG3963@1|root,COG3963@2|Bacteria,4NPMV@976|Bacteroidetes,1IYWA@117747|Sphingobacteriia 976|Bacteroidetes I Ribosomal RNA adenine dimethylase - - - - - - - - - - - - MTS,Methyltransf_25,RrnaAD DYD1_k127_4685056_2 1313421.JHBV01000008_gene4392 3.775e-07 54.0 COG0457@1|root,COG0457@2|Bacteria,4P298@976|Bacteroidetes,1J19F@117747|Sphingobacteriia 976|Bacteroidetes S WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40,TPR_19 DYD1_k127_4688102_0 331113.SNE_A19420 2.358e-114 381.0 2CCDD@1|root,2Z99Z@2|Bacteria,2JFXI@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4688102_3 745411.B3C1_04575 5.61e-94 326.0 COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1J58C@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG2939 Carboxypeptidase C (cathepsin A) - - - - - - - - - - - - Peptidase_S10 DYD1_k127_4688102_4 926560.KE387027_gene540 1.935e-84 298.0 COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 DYD1_k127_4688102_5 2325.TKV_c08560 6.355e-37 147.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,42FCF@68295|Thermoanaerobacterales 186801|Clostridia E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS17035 DapB_C,DapB_N DYD1_k127_4688102_1 1444712.BN1013_01450 5.523e-109 359.0 COG2877@1|root,COG2877@2|Bacteria,2JFD5@204428|Chlamydiae 204428|Chlamydiae M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 DYD1_k127_4688102_7 331113.SNE_A19450 2.488e-05 55.0 2EJY2@1|root,32RJ1@2|Bacteria,2JG98@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4688102_2 1444711.CCJF01000005_gene845 2.878e-104 343.0 COG1137@1|root,COG1137@2|Bacteria,2JFFD@204428|Chlamydiae 204428|Chlamydiae S ABC transporter lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran DYD1_k127_4688102_6 69042.WH5701_06631 3.215e-23 100.0 COG1373@1|root,COG1373@2|Bacteria,1GRNG@1117|Cyanobacteria,1H2G8@1129|Synechococcus 1117|Cyanobacteria S Domain of unknown function (DUF4143) - - - - - - - - - - - - AAA_14,DUF4143 DYD1_k127_4704112_6 765952.PUV_13140 1.942e-08 56.0 COG0120@1|root,COG0120@2|Bacteria,2JG19@204428|Chlamydiae 204428|Chlamydiae G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A DYD1_k127_4704112_7 32507.XP_006782115.1 1.209e-06 58.0 KOG2177@1|root,KOG2177@2759|Eukaryota,38F8S@33154|Opisthokonta,3BIN3@33208|Metazoa,3D3GF@33213|Bilateria,48C0K@7711|Chordata,48YGC@7742|Vertebrata,49VS8@7898|Actinopterygii 33208|Metazoa O Tripartite motif containing 105 - - 2.3.2.27 ko:K12034 - - - - ko00000,ko01000,ko04121 - - - PRY,SPRY,zf-C3HC4,zf-C3HC4_4,zf-RING_UBOX DYD1_k127_4704112_4 331113.SNE_A07890 2.944e-29 120.0 COG1925@1|root,COG1925@2|Bacteria,2JGB0@204428|Chlamydiae 204428|Chlamydiae G PTS HPr component phosphorylation site - - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr DYD1_k127_4704112_1 1444711.CCJF01000005_gene1113 1.102e-196 631.0 COG1164@1|root,COG1164@2|Bacteria,2JFQ1@204428|Chlamydiae 204428|Chlamydiae E oligoendopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N DYD1_k127_4704112_2 331113.SNE_A07860 1.081e-37 143.0 COG0234@1|root,COG0234@2|Bacteria,2JG6X@204428|Chlamydiae 204428|Chlamydiae O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD1_k127_4704112_0 331113.SNE_A07850 8.298e-250 780.0 COG0459@1|root,COG0459@2|Bacteria,2JFDX@204428|Chlamydiae 204428|Chlamydiae O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0005575,GO:0005576,GO:0005623,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0010646,GO:0010647,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0065007,GO:0065010,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:2000535 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD1_k127_4704112_5 766499.C357_04802 5.508e-20 98.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2U78A@28211|Alphaproteobacteria 28211|Alphaproteobacteria O DedA family dedA - - - - - - - - - - - SNARE_assoc DYD1_k127_4704112_3 1444711.CCJF01000005_gene737 6.986e-32 130.0 COG0791@1|root,COG0791@2|Bacteria,2JGVF@204428|Chlamydiae 204428|Chlamydiae M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 DYD1_k127_4726449_2 331113.SNE_A05140 6.997e-119 394.0 COG1108@1|root,COG1321@1|root,COG1108@2|Bacteria,COG1321@2|Bacteria,2JFJ5@204428|Chlamydiae 204428|Chlamydiae P transport system membrane protein ytgC - - ko:K11708 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC-3,Fe_dep_repr_C DYD1_k127_4726449_3 765952.PUV_02120 1.222e-93 313.0 COG1121@1|root,COG1121@2|Bacteria,2JFS6@204428|Chlamydiae 204428|Chlamydiae P Part of an ATP-driven transport system CPn0346 CPn0347 CPn0348 CPn0349 for a metal. Probably responsible for energy coupling to the transport system CP_0412 - - ko:K11710 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC_tran DYD1_k127_4726449_4 716544.wcw_1673 3.793e-92 314.0 COG0803@1|root,COG0803@2|Bacteria,2JFSX@204428|Chlamydiae 204428|Chlamydiae P Belongs to the bacterial solute-binding protein 9 family troA - - ko:K11707 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA DYD1_k127_4726449_5 331113.SNE_A05070 1.859e-62 219.0 2CDV0@1|root,3071V@2|Bacteria,2JG2K@204428|Chlamydiae 204428|Chlamydiae - - CP_0409 - - - - - - - - - - - - DYD1_k127_4726449_1 244582.JQAK01000001_gene1694 2.583e-201 639.0 COG3202@1|root,COG3202@2|Bacteria,1MVS9@1224|Proteobacteria,2TSSJ@28211|Alphaproteobacteria,47EX6@766|Rickettsiales 766|Rickettsiales C Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism tlc1 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006862,GO:0008150,GO:0015711,GO:0015748,GO:0015865,GO:0015867,GO:0015868,GO:0015893,GO:0015931,GO:0016020,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051503,GO:0071702,GO:0071705,GO:0071944,GO:1901264 - ko:K03301 - - - - ko00000 2.A.12 - - TLC DYD1_k127_4726449_0 1437425.CSEC_1854 3.222e-209 657.0 COG0481@1|root,COG0481@2|Bacteria,2JFFF@204428|Chlamydiae 204428|Chlamydiae J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C DYD1_k127_4738572_1 765952.PUV_00070 2.173e-115 385.0 COG0468@1|root,COG0468@2|Bacteria,2JFVU@204428|Chlamydiae 204428|Chlamydiae L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD1_k127_4738572_2 331113.SNE_A00740 3.013e-105 350.0 COG0837@1|root,COG0837@2|Bacteria,2JH4J@204428|Chlamydiae 204428|Chlamydiae H Glucokinase glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase DYD1_k127_4738572_0 331113.SNE_A17870 3.06e-233 734.0 COG1452@1|root,COG1452@2|Bacteria,2JGPM@204428|Chlamydiae 2|Bacteria M Glycosyl hydrolase family 63 C-terminal domain - - - ko:K22110 - - - - ko00000,ko02000 1.B.35.1,1.B.35.2 - - Glyco_hydro_63 DYD1_k127_4796258_3 1444711.CCJF01000004_gene1941 6.942e-18 92.0 COG0553@1|root,COG0553@2|Bacteria,2JFHJ@204428|Chlamydiae 204428|Chlamydiae L swi snf helicase family - - - - - - - - - - - - Helicase_C,SNF2_N DYD1_k127_4796258_1 1444711.CCJF01000004_gene1943 1.08e-118 390.0 COG1054@1|root,COG1054@2|Bacteria,2JFNW@204428|Chlamydiae 204428|Chlamydiae S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C DYD1_k127_4796258_2 716544.wcw_1570 2.102e-84 284.0 COG0522@1|root,COG0522@2|Bacteria,2JFKA@204428|Chlamydiae 204428|Chlamydiae J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 DYD1_k127_4796258_0 762903.Pedsa_1933 2.167e-154 501.0 COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia 976|Bacteroidetes E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 DYD1_k127_4817997_0 1444711.CCJF01000004_gene2142 3.399e-53 195.0 COG1794@1|root,COG1794@2|Bacteria 2|Bacteria M racemase activity, acting on amino acids and derivatives racX - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race DYD1_k127_4817997_3 1243664.CAVL020000035_gene2736 2.294e-18 98.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 DYD1_k127_4817997_1 765952.PUV_17460 3.031e-34 142.0 COG2197@1|root,COG2197@2|Bacteria,2JH8F@204428|Chlamydiae 204428|Chlamydiae K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE DYD1_k127_4822297_0 700598.Niako_2458 8.05e-18 83.0 2E328@1|root,32Y2G@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4822297_1 1403948.Q618_VCMC00003G0435 3.364e-05 46.0 COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4D4KA@85005|Actinomycetales 201174|Actinobacteria P phosphate transporter pitH - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 DYD1_k127_4822314_1 331113.SNE_A17150 3.531e-34 134.0 COG1366@1|root,COG1366@2|Bacteria,2JG89@204428|Chlamydiae 204428|Chlamydiae T STAS domain - - - ko:K06378 - - - - ko00000 - - - STAS DYD1_k127_4822314_0 264201.pc1243 1.453e-116 384.0 COG0324@1|root,COG0324@2|Bacteria,2JFKY@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT,PPV_E1_C DYD1_k127_4822314_3 335543.Sfum_2433 4.347e-05 55.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42RS1@68525|delta/epsilon subdivisions,2WNR1@28221|Deltaproteobacteria,2MQVG@213462|Syntrophobacterales 28221|Deltaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N DYD1_k127_4822314_2 573063.Metin_0013 8.86e-25 115.0 COG0530@1|root,arCOG02881@2157|Archaea,2XVHN@28890|Euryarchaeota,23QPK@183939|Methanococci 183939|Methanococci P PFAM Sodium calcium exchanger membrane region - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0008150,GO:0008273,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015081,GO:0015085,GO:0015267,GO:0015291,GO:0015297,GO:0015298,GO:0015318,GO:0015368,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022803,GO:0022804,GO:0022821,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030955,GO:0031224,GO:0031226,GO:0031402,GO:0031420,GO:0034220,GO:0035725,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070588,GO:0070838,GO:0071804,GO:0071805,GO:0071944,GO:0072503,GO:0072507,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516 - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD1_k127_4833132_5 331113.SNE_A12600 4.374e-50 182.0 COG0691@1|root,COG0691@2|Bacteria,2JG73@204428|Chlamydiae 204428|Chlamydiae J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB DYD1_k127_4833132_6 765952.PUV_11210 1.503e-25 112.0 COG1495@1|root,COG1495@2|Bacteria 2|Bacteria O protein disulfide oxidoreductase activity lidJ - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB DYD1_k127_4833132_1 331113.SNE_A12610 1.164e-133 437.0 COG0592@1|root,COG0592@2|Bacteria,2JFQ0@204428|Chlamydiae 204428|Chlamydiae L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 DYD1_k127_4833132_2 331113.SNE_A12620 1.495e-81 283.0 COG1195@1|root,COG1195@2|Bacteria,2JG0T@204428|Chlamydiae 204428|Chlamydiae L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N DYD1_k127_4833132_0 1444711.CCJF01000004_gene2420 3.571e-211 670.0 COG0166@1|root,COG0166@2|Bacteria,2JFI4@204428|Chlamydiae 204428|Chlamydiae F glucose-6-phosphate isomerase pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI DYD1_k127_4833132_8 331113.SNE_A12710 9.102e-18 93.0 2ED9E@1|root,3375V@2|Bacteria,2JGFV@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_4833132_3 331113.SNE_A12720 5.774e-55 199.0 COG0220@1|root,COG0220@2|Bacteria,2JG2D@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 DYD1_k127_4833132_4 331113.SNE_A12730 6.326e-52 190.0 COG0811@1|root,COG0811@2|Bacteria 2|Bacteria U bacteriocin transport - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB DYD1_k127_4833132_7 331113.SNE_A12740 1.194e-22 103.0 COG0848@1|root,COG0848@2|Bacteria 2|Bacteria U biopolymer transport protein - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD DYD1_k127_4833132_9 765952.PUV_09470 1.599e-12 67.0 COG1961@1|root,COG1961@2|Bacteria 2|Bacteria L recombinase activity - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom DYD1_k127_4833132_10 4565.Traes_1DL_50C4F942D.1 0.0007542 50.0 COG0631@1|root,KOG0698@2759|Eukaryota,37N6C@33090|Viridiplantae,3GBMH@35493|Streptophyta,3KUTD@4447|Liliopsida,3I91Q@38820|Poales 35493|Streptophyta T Serine/threonine phosphatases, family 2C, catalytic domain - - 3.1.3.16 ko:K17506 - - - - ko00000,ko01000,ko01009 - - - PP2C DYD1_k127_4910771_1 1499968.TCA2_5936 1.496e-21 101.0 COG3230@1|root,COG3230@2|Bacteria,1VVFM@1239|Firmicutes,4HW5B@91061|Bacilli,26XWT@186822|Paenibacillaceae 91061|Bacilli P Heme oxygenase - - - - - - - - - - - - Heme_oxygenase DYD1_k127_4910771_2 1444712.BN1013_00365 6.863e-18 94.0 COG0454@1|root,COG1051@1|root,COG0456@2|Bacteria,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity FNV0100 - - - - - - - - - - - NUDIX DYD1_k127_4910771_0 419610.Mext_1482 8.797e-30 130.0 COG1051@1|root,COG1051@2|Bacteria,1N1W3@1224|Proteobacteria,2UAMY@28211|Alphaproteobacteria,1JUSI@119045|Methylobacteriaceae 28211|Alphaproteobacteria F NUDIX domain - - - - - - - - - - - - NUDIX DYD1_k127_4911172_1 179408.Osc7112_3686 2.203e-60 218.0 COG1192@1|root,COG1192@2|Bacteria,1G3X7@1117|Cyanobacteria,1H7FD@1150|Oscillatoriales 1117|Cyanobacteria D Anion-transporting ATPase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD1_k127_4911172_2 932678.THERU_01990 7.311e-30 121.0 2DN43@1|root,32VED@2|Bacteria,2G54E@200783|Aquificae 200783|Aquificae - - - - - - - - - - - - - - - DYD1_k127_4911172_0 436114.SYO3AOP1_1344 1.983e-145 473.0 COG2217@1|root,COG2217@2|Bacteria,2G4GR@200783|Aquificae 2|Bacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.4 ko:K01533,ko:K12950 - - R00086 RC00002 ko00000,ko01000 3.A.3.32,3.A.3.5 - - E1-E2_ATPase,Hydrolase DYD1_k127_4943103_0 716544.wcw_1228 1.06e-43 163.0 COG0272@1|root,COG0272@2|Bacteria,2JFKS@204428|Chlamydiae 204428|Chlamydiae L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 DYD1_k127_4943103_1 331113.SNE_A02840 8.68e-22 110.0 COG3468@1|root,COG3468@2|Bacteria,2JHAK@204428|Chlamydiae 204428|Chlamydiae MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - - DYD1_k127_4943103_2 1444711.CCJF01000005_gene1797 2.539e-18 95.0 298R7@1|root,2ZVVI@2|Bacteria,2JHEH@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_495322_5 1437425.CSEC_1875 4.65e-35 137.0 COG0593@1|root,COG0593@2|Bacteria,2JFNG@204428|Chlamydiae 204428|Chlamydiae L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA2 - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N DYD1_k127_495322_1 86106.I862_06075 2.176e-101 339.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,47F2C@766|Rickettsiales 766|Rickettsiales O COG0330 Membrane protease subunits, stomatin prohibitin homologs hflC1 - - - - - - - - - - - Band_7,Band_7_C DYD1_k127_495322_7 716544.wcw_0274 5.357e-14 79.0 COG1040@1|root,COG1040@2|Bacteria,2JGGZ@204428|Chlamydiae 204428|Chlamydiae S competence protein - - - - - - - - - - - - Pribosyltran DYD1_k127_495322_2 331113.SNE_A04800 9.49e-61 240.0 28JF8@1|root,2Z997@2|Bacteria,2JFNE@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_495322_4 1150474.JQJI01000004_gene394 4.264e-40 151.0 COG0509@1|root,COG0509@2|Bacteria,2GD57@200918|Thermotogae 200918|Thermotogae E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H DYD1_k127_495322_3 1444712.BN1013_00158 1.101e-60 216.0 2BM0T@1|root,32FHQ@2|Bacteria,2JG26@204428|Chlamydiae 204428|Chlamydiae S Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 DYD1_k127_495322_0 331113.SNE_A04650 4.726e-106 368.0 28JYE@1|root,2Z9NP@2|Bacteria,2JFF3@204428|Chlamydiae 204428|Chlamydiae - - CP_0319 - - - - - - - - - - - SurA_N_3 DYD1_k127_495322_9 94624.Bpet4198 1.158e-05 48.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VH1Q@28216|Betaproteobacteria,3T37I@506|Alcaligenaceae 28216|Betaproteobacteria C oxidoreductases (related to aryl-alcohol dehydrogenases) yakC - - - - - - - - - - - Aldo_ket_red DYD1_k127_4973079_2 1268237.G114_15511 2.882e-19 89.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1Y3DN@135624|Aeromonadales 135624|Aeromonadales V Multidrug resistance protein MdtK - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD1_k127_4973079_3 1444712.BN1013_01887 2.533e-07 60.0 COG1215@1|root,COG1215@2|Bacteria,2JFJB@204428|Chlamydiae 204428|Chlamydiae M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_4973079_0 1209989.TepiRe1_0703 1.746e-177 567.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b DYD1_k127_4973079_1 1444712.BN1013_01886 5.309e-23 104.0 COG3011@1|root,COG3011@2|Bacteria,2JG92@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 DYD1_k127_5001265_1 331113.SNE_A05780 2.339e-180 580.0 COG1109@1|root,COG1109@2|Bacteria,2JFUP@204428|Chlamydiae 204428|Chlamydiae G Phosphoglucomutase phosphomannomutase pgcA - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_5001265_2 1094980.Mpsy_2921 1.597e-58 207.0 COG0225@1|root,arCOG02816@2157|Archaea,2XWKA@28890|Euryarchaeota,2N9M6@224756|Methanomicrobia 224756|Methanomicrobia O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR DYD1_k127_5001265_0 765952.PUV_24140 1.7e-196 629.0 COG1480@1|root,COG1480@2|Bacteria,2JFF5@204428|Chlamydiae 204428|Chlamydiae S Metal dependent phosphohydrolases with conserved 'HD' motif. yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD DYD1_k127_5050754_2 702450.CUW_1593 4.013e-13 72.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,3VUWM@526524|Erysipelotrichia 526524|Erysipelotrichia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_506050_0 1392490.JHZX01000001_gene3060 0.0002878 53.0 COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,1HWYS@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA_2,TPR_12,TPR_8,Y_Y_Y DYD1_k127_5063471_4 331113.SNE_A17600 4.497e-18 89.0 COG0196@1|root,COG0196@2|Bacteria,2JFXU@204428|Chlamydiae 204428|Chlamydiae H riboflavin biosynthesis protein ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase DYD1_k127_5063471_2 331113.SNE_A17590 2.095e-78 269.0 COG0130@1|root,COG0130@2|Bacteria,2JFXN@204428|Chlamydiae 204428|Chlamydiae J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C_2,TruB_N DYD1_k127_5063471_3 500633.CLOHIR_01222 1.53e-18 90.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,25RK5@186804|Peptostreptococcaceae 186801|Clostridia J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA DYD1_k127_5063471_0 716544.wcw_0858 5.616e-254 805.0 COG0532@1|root,COG0810@1|root,COG0532@2|Bacteria,COG0810@2|Bacteria,2JFVG@204428|Chlamydiae 204428|Chlamydiae J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N DYD1_k127_5063471_1 264201.pc0762 1.213e-163 524.0 COG0195@1|root,COG0195@2|Bacteria,2JFHD@204428|Chlamydiae 204428|Chlamydiae K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 DYD1_k127_5105767_0 1121289.JHVL01000027_gene225 1.306e-204 662.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,36DR6@31979|Clostridiaceae 186801|Clostridia L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V DYD1_k127_5131815_4 7213.XP_004533635.1 1.512e-16 93.0 KOG0660@1|root,KOG0660@2759|Eukaryota,38BZX@33154|Opisthokonta,3B9J2@33208|Metazoa,3CRHP@33213|Bilateria,41UW5@6656|Arthropoda,3SH36@50557|Insecta,455HA@7147|Diptera 33208|Metazoa T MAP kinase activity. It is involved in the biological process described with protein phosphorylation MAPK14 GO:0000003,GO:0000075,GO:0000077,GO:0000165,GO:0000166,GO:0000187,GO:0000302,GO:0000303,GO:0000305,GO:0000902,GO:0000922,GO:0001501,GO:0001502,GO:0001525,GO:0001558,GO:0001568,GO:0001756,GO:0001775,GO:0001817,GO:0001819,GO:0001890,GO:0001932,GO:0001934,GO:0001944,GO:0002062,GO:0002225,GO:0002237,GO:0002251,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002385,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002718,GO:0002720,GO:0002739,GO:0002741,GO:0002759,GO:0002760,GO:0002784,GO:0002791,GO:0002793,GO:0002831,GO:0002832,GO:0002833,GO:0002920,GO:0002921,GO:0002922,GO:0003002,GO:0003006,GO:0003007,GO:0003008,GO:0003012,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004707,GO:0004708,GO:0004712,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005819,GO:0005829,GO:0005856,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006629,GO:0006631,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006935,GO:0006936,GO:0006939,GO:0006950,GO:0006952,GO:0006955,GO:0006970,GO:0006972,GO:0006974,GO:0006979,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007178,GO:0007267,GO:0007275,GO:0007389,GO:0007399,GO:0007507,GO:0007517,GO:0007519,GO:0007564,GO:0007568,GO:0007569,GO:0007610,GO:0008022,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008285,GO:0008340,GO:0008348,GO:0008361,GO:0009266,GO:0009314,GO:0009408,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009612,GO:0009615,GO:0009617,GO:0009620,GO:0009628,GO:0009636,GO:0009653,GO:0009743,GO:0009746,GO:0009749,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009952,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010212,GO:0010243,GO:0010259,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010646,GO:0010647,GO:0010648,GO:0010758,GO:0010759,GO:0010769,GO:0010827,GO:0010828,GO:0010830,GO:0010831,GO:0010883,GO:0010941,GO:0010952,GO:0010975,GO:0012501,GO:0012505,GO:0014706,GO:0014835,GO:0015630,GO:0016043,GO:0016192,GO:0016202,GO:0016301,GO:0016310,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016773,GO:0016909,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019395,GO:0019538,GO:0019752,GO:0019899,GO:0019900,GO:0019901,GO:0019902,GO:0019903,GO:0022008,GO:0022414,GO:0022603,GO:0022604,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030097,GO:0030099,GO:0030111,GO:0030141,GO:0030154,GO:0030162,GO:0030178,GO:0030258,GO:0030278,GO:0030316,GO:0030334,GO:0030335,GO:0030534,GO:0030554,GO:0031098,GO:0031099,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031344,GO:0031347,GO:0031349,GO:0031399,GO:0031401,GO:0031410,GO:0031570,GO:0031647,GO:0031663,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032103,GO:0032147,GO:0032268,GO:0032270,GO:0032386,GO:0032388,GO:0032495,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032553,GO:0032555,GO:0032559,GO:0032655,GO:0032735,GO:0032787,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0033157,GO:0033554,GO:0033674,GO:0033993,GO:0034097,GO:0034284,GO:0034440,GO:0034599,GO:0034612,GO:0034614,GO:0034644,GO:0034762,GO:0034764,GO:0034774,GO:0035094,GO:0035095,GO:0035239,GO:0035282,GO:0035295,GO:0035556,GO:0035639,GO:0035924,GO:0035994,GO:0036094,GO:0036211,GO:0036230,GO:0038001,GO:0038066,GO:0040007,GO:0040008,GO:0040011,GO:0040012,GO:0040016,GO:0040017,GO:0042060,GO:0042119,GO:0042127,GO:0042221,GO:0042246,GO:0042306,GO:0042307,GO:0042325,GO:0042327,GO:0042330,GO:0042493,GO:0042542,GO:0042594,GO:0042692,GO:0042742,GO:0042770,GO:0043009,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043403,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043436,GO:0043487,GO:0043488,GO:0043489,GO:0043549,GO:0043900,GO:0043901,GO:0043902,GO:0044093,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044433,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045055,GO:0045087,GO:0045321,GO:0045445,GO:0045595,GO:0045597,GO:0045598,GO:0045600,GO:0045637,GO:0045639,GO:0045646,GO:0045648,GO:0045661,GO:0045663,GO:0045664,GO:0045786,GO:0045793,GO:0045843,GO:0045844,GO:0045859,GO:0045860,GO:0045862,GO:0045893,GO:0045926,GO:0045927,GO:0045934,GO:0045935,GO:0045937,GO:0045944,GO:0046324,GO:0046326,GO:0046620,GO:0046621,GO:0046622,GO:0046677,GO:0046685,GO:0046686,GO:0046777,GO:0046822,GO:0046824,GO:0046903,GO:0048010,GO:0048070,GO:0048079,GO:0048082,GO:0048255,GO:0048273,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048608,GO:0048634,GO:0048635,GO:0048636,GO:0048638,GO:0048639,GO:0048640,GO:0048646,GO:0048670,GO:0048696,GO:0048699,GO:0048705,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050727,GO:0050767,GO:0050770,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050829,GO:0050830,GO:0050832,GO:0050896,GO:0050920,GO:0050921,GO:0051019,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051272,GO:0051301,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051403,GO:0051525,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051960,GO:0052547,GO:0055021,GO:0055022,GO:0055023,GO:0055024,GO:0055025,GO:0055026,GO:0055114,GO:0060043,GO:0060044,GO:0060045,GO:0060142,GO:0060143,GO:0060205,GO:0060255,GO:0060284,GO:0060341,GO:0060420,GO:0060421,GO:0060429,GO:0060537,GO:0060538,GO:0060548,GO:0060828,GO:0061013,GO:0061053,GO:0061061,GO:0061117,GO:0061387,GO:0061448,GO:0061458,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070391,GO:0070555,GO:0070848,GO:0070887,GO:0070935,GO:0071214,GO:0071216,GO:0071219,GO:0071222,GO:0071223,GO:0071241,GO:0071243,GO:0071248,GO:0071276,GO:0071310,GO:0071345,GO:0071347,GO:0071356,GO:0071363,GO:0071396,GO:0071478,GO:0071479,GO:0071482,GO:0071622,GO:0071675,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0072358,GO:0072359,GO:0072593,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0090087,GO:0090090,GO:0090316,GO:0090335,GO:0090336,GO:0090398,GO:0090400,GO:0093002,GO:0097159,GO:0097367,GO:0097708,GO:0098542,GO:0098586,GO:0098743,GO:0099503,GO:0101002,GO:0104004,GO:0120035,GO:0140096,GO:1900015,GO:1900150,GO:1900180,GO:1900182,GO:1900407,GO:1900424,GO:1900426,GO:1901214,GO:1901215,GO:1901244,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901698,GO:1901700,GO:1901701,GO:1901739,GO:1901741,GO:1901796,GO:1901861,GO:1901862,GO:1901863,GO:1902097,GO:1902369,GO:1902373,GO:1902531,GO:1902533,GO:1902680,GO:1902882,GO:1903311,GO:1903312,GO:1903506,GO:1903508,GO:1903530,GO:1903532,GO:1903706,GO:1903708,GO:1903827,GO:1903829,GO:1904589,GO:1904591,GO:1904813,GO:1904951,GO:1905048,GO:1905050,GO:1905521,GO:1905523,GO:1905952,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2000377,GO:2000379,GO:2001141,GO:2001182,GO:2001184 2.7.11.24 ko:K04441 ko01522,ko04010,ko04011,ko04013,ko04015,ko04068,ko04071,ko04139,ko04212,ko04218,ko04261,ko04370,ko04380,ko04550,ko04611,ko04620,ko04621,ko04622,ko04624,ko04657,ko04658,ko04659,ko04660,ko04664,ko04668,ko04670,ko04714,ko04722,ko04723,ko04728,ko04750,ko04912,ko04914,ko04917,ko04926,ko04933,ko05014,ko05120,ko05131,ko05132,ko05133,ko05140,ko05142,ko05145,ko05152,ko05160,ko05164,ko05167,ko05169,ko05205,ko05418,map01522,map04010,map04011,map04013,map04015,map04068,map04071,map04139,map04212,map04218,map04261,map04370,map04380,map04550,map04611,map04620,map04621,map04622,map04624,map04657,map04658,map04659,map04660,map04664,map04668,map04670,map04714,map04722,map04723,map04728,map04750,map04912,map04914,map04917,map04926,map04933,map05014,map05120,map05131,map05132,map05133,map05140,map05142,map05145,map05152,map05160,map05164,map05167,map05169,map05205,map05418 M00689 - - ko00000,ko00001,ko00002,ko01000,ko01001 - - - Pkinase DYD1_k127_5131815_3 331113.SNE_A14880 5.332e-57 201.0 COG0636@1|root,COG0636@2|Bacteria,2JG1V@204428|Chlamydiae 204428|Chlamydiae C ATP synthase, subunit atpK - - ko:K02124 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_C DYD1_k127_5131815_0 331113.SNE_A14890 1.364e-177 576.0 COG1269@1|root,COG1269@2|Bacteria,2JFCG@204428|Chlamydiae 204428|Chlamydiae C ATP synthase, subunit I atpI - - ko:K02123 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - V_ATPase_I DYD1_k127_5131815_2 331113.SNE_A14900 7.298e-59 210.0 COG1394@1|root,COG1394@2|Bacteria,2JG3P@204428|Chlamydiae 204428|Chlamydiae C Produces ATP from ADP in the presence of a proton gradient across the membrane atpD - - ko:K02120 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_D DYD1_k127_5131815_1 1437425.CSEC_1136 1.149e-123 398.0 COG1156@1|root,COG1156@2|Bacteria,2JFMM@204428|Chlamydiae 204428|Chlamydiae F Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit atpB - - ko:K02118 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_ab,ATP-synt_ab_N DYD1_k127_5150601_2 331113.SNE_A20940 8.752e-19 96.0 COG3210@1|root,COG3210@2|Bacteria,2JGX3@204428|Chlamydiae 204428|Chlamydiae U Parallel beta-helix repeats - - - - - - - - - - - - - DYD1_k127_5150601_0 331113.SNE_A03430 3.734e-104 358.0 COG2831@1|root,COG2831@2|Bacteria 2|Bacteria U hemolysin activation secretion protein - - - - - - - - - - - - POTRA,POTRA_2,ShlB DYD1_k127_5150601_1 373994.Riv7116_3645 5.698e-33 139.0 COG0697@1|root,COG0697@2|Bacteria,1G4FV@1117|Cyanobacteria 1117|Cyanobacteria EG integral membrane protein - - - - - - - - - - - - EamA DYD1_k127_5155680_5 716544.wcw_0324 2.522e-30 126.0 COG1075@1|root,COG1075@2|Bacteria,2JGD8@204428|Chlamydiae 204428|Chlamydiae S Lipase (class 2) - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_5155680_1 331113.SNE_A10750 9.925e-66 233.0 COG5373@1|root,COG5373@2|Bacteria 2|Bacteria KLT membrane - - - - - - - - - - - - DUF2339 DYD1_k127_5155680_3 264201.pc0766 2.072e-54 209.0 COG4166@1|root,COG4166@2|Bacteria,2JFKE@204428|Chlamydiae 204428|Chlamydiae E transmembrane transport - - - - - - - - - - - - - DYD1_k127_5155680_0 331113.SNE_A10700 9.291e-110 374.0 COG4166@1|root,COG4166@2|Bacteria,2JFE2@204428|Chlamydiae 204428|Chlamydiae E peptide ABC transporter, periplasmic oppA_2 - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 DYD1_k127_5155680_7 706587.Desti_2706 0.0005772 48.0 COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,42TT1@68525|delta/epsilon subdivisions,2WQT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Membrane protein of - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 DYD1_k127_5155680_6 331113.SNE_A12100 1.433e-05 52.0 COG1950@1|root,COG1950@2|Bacteria,2JGJZ@204428|Chlamydiae 204428|Chlamydiae S Mycobacterial 4 TMS phage holin, superfamily IV - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 DYD1_k127_5155680_2 765952.PUV_17670 2.948e-57 209.0 COG3271@1|root,COG3271@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Peptidase_C39_2 DYD1_k127_5155680_4 331113.SNE_A11440 4.848e-40 157.0 COG0477@1|root,COG2814@2|Bacteria,2JGQX@204428|Chlamydiae 204428|Chlamydiae EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_5181711_1 331113.SNE_A22770 1.144e-107 368.0 COG1215@1|root,COG1215@2|Bacteria,2JH6V@204428|Chlamydiae 204428|Chlamydiae M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_5181711_0 716544.wcw_1370 1.622e-243 780.0 COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,2JFJE@204428|Chlamydiae 204428|Chlamydiae IQ AMP-binding enzyme aas - 6.2.1.20 ko:K01909 ko00071,map00071 - R01406 RC00014,RC00039 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase,PP-binding DYD1_k127_5181711_2 1444712.BN1013_01178 5.621e-90 301.0 COG0215@1|root,COG0215@2|Bacteria,2JFNB@204428|Chlamydiae 204428|Chlamydiae J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e DYD1_k127_518553_2 331113.SNE_A08750 4.63e-23 100.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups rfaG - - ko:K02844 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_518553_0 331113.SNE_A08740 5.431e-148 480.0 COG1560@1|root,COG1560@2|Bacteria,2JH1S@204428|Chlamydiae 204428|Chlamydiae M Bacterial lipid A biosynthesis acyltransferase CP_0676 - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD1_k127_518553_1 331113.SNE_A08730 7.122e-50 186.0 COG1385@1|root,COG1385@2|Bacteria,2JG7Y@204428|Chlamydiae 204428|Chlamydiae J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA DYD1_k127_518553_4 246194.CHY_1144 4.719e-07 53.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,42F1S@68295|Thermoanaerobacterales 186801|Clostridia G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C DYD1_k127_5259877_2 264201.pc1226 1.869e-177 564.0 COG0621@1|root,COG0621@2|Bacteria,2JFRX@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,UPF0004 DYD1_k127_5259877_11 485913.Krac_7286 3.344e-13 72.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily ywtG - - - - - - - - - - - Sugar_tr DYD1_k127_5259877_5 406552.NJ7G_0084 2.324e-100 339.0 arCOG02685@1|root,arCOG02685@2157|Archaea,2XV10@28890|Euryarchaeota,23SHT@183963|Halobacteria 183963|Halobacteria G COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - Sugar_tr DYD1_k127_5259877_1 331113.SNE_A11650 1.084e-178 564.0 COG1830@1|root,COG1830@2|Bacteria,2JFHK@204428|Chlamydiae 204428|Chlamydiae G Fructose-bisphosphate aldolase class fbaB - 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - DeoC DYD1_k127_5259877_3 765952.PUV_11060 2.291e-148 483.0 COG0557@1|root,COG0557@2|Bacteria 2|Bacteria K exoribonuclease II activity rnb - 3.1.13.1 ko:K01147,ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 DYD1_k127_5259877_9 716544.wcw_1086 1.305e-39 164.0 COG2982@1|root,COG2982@2|Bacteria,2JFZM@204428|Chlamydiae 204428|Chlamydiae M Protein involved in outer membrane biogenesis CP_0578 - - - - - - - - - - - - DYD1_k127_5259877_8 331113.SNE_A11670 6.25e-52 189.0 COG0494@1|root,COG0494@2|Bacteria,2JGDU@204428|Chlamydiae 204428|Chlamydiae L NUDIX domain - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX DYD1_k127_5259877_0 331113.SNE_A13270 2.348e-190 611.0 COG0449@1|root,COG0449@2|Bacteria,2JFJR@204428|Chlamydiae 204428|Chlamydiae M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS DYD1_k127_5259877_7 1444711.CCJF01000005_gene1269 1.842e-79 272.0 COG0500@1|root,COG2226@2|Bacteria,2JHHE@204428|Chlamydiae 204428|Chlamydiae Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_5259877_12 882083.SacmaDRAFT_2681 0.0001544 55.0 COG0707@1|root,COG0707@2|Bacteria,2GREI@201174|Actinobacteria,4E1WX@85010|Pseudonocardiales 201174|Actinobacteria M Monogalactosyldiacylglycerol (MGDG) synthase - - - - - - - - - - - - DUF1298,Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth,WES_acyltransf DYD1_k127_5259877_6 331113.SNE_A13250 5.46e-89 303.0 COG2239@1|root,COG2239@2|Bacteria,2JG1N@204428|Chlamydiae 204428|Chlamydiae P Divalent cation transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE DYD1_k127_5259877_4 716544.wcw_1263 1.787e-144 471.0 COG0531@1|root,COG0531@2|Bacteria,2JFCI@204428|Chlamydiae 204428|Chlamydiae E Amino acid permease - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 DYD1_k127_5263125_7 264201.pc0660 1.502e-21 99.0 COG1561@1|root,COG1561@2|Bacteria,2JG0Y@204428|Chlamydiae 204428|Chlamydiae S Domain of unknown function (DUF1732) - - - - - - - - - - - - DUF1732,YicC_N DYD1_k127_5263125_6 331113.SNE_A10630 1.696e-23 105.0 COG2389@1|root,COG2389@2|Bacteria 2|Bacteria S metal-binding protein - - - - - - - - - - - - DUF2227 DYD1_k127_5263125_3 264201.pc0658 1.539e-69 242.0 COG0164@1|root,COG0164@2|Bacteria,2JFYJ@204428|Chlamydiae 204428|Chlamydiae L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII DYD1_k127_5263125_4 331113.SNE_A07600 5.254e-41 156.0 COG0335@1|root,COG0335@2|Bacteria,2JG56@204428|Chlamydiae 204428|Chlamydiae J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 DYD1_k127_5263125_2 716544.wcw_0699 1.543e-93 312.0 COG0336@1|root,COG0336@2|Bacteria,2JFXJ@204428|Chlamydiae 204428|Chlamydiae J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT DYD1_k127_5263125_5 264201.pc0655 7.377e-25 106.0 COG0228@1|root,COG0228@2|Bacteria,2JGCH@204428|Chlamydiae 204428|Chlamydiae J Belongs to the bacterial ribosomal protein bS16 family rpsP - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 DYD1_k127_5263125_1 1444711.CCJF01000005_gene1770 1.902e-177 567.0 COG0541@1|root,COG0541@2|Bacteria,2JFVZ@204428|Chlamydiae 204428|Chlamydiae U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB DYD1_k127_5263125_0 523845.AQXV01000019_gene364 6.264e-200 641.0 COG0474@1|root,arCOG01578@2157|Archaea,2XT4B@28890|Euryarchaeota,23QDK@183939|Methanococci 183939|Methanococci P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 DYD1_k127_526704_2 331113.SNE_A14530 1.517e-22 99.0 2EAAF@1|root,334ES@2|Bacteria,2JGCU@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_526704_1 1007103.AFHW01000087_gene6313 1.252e-75 271.0 COG4403@1|root,COG4403@2|Bacteria,1V13V@1239|Firmicutes,4HFSX@91061|Bacilli,26TU0@186822|Paenibacillaceae 91061|Bacilli V Lanthionine synthetase C-like protein spaC1 - - ko:K20484 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - LANC_like DYD1_k127_526704_0 765952.PUV_03460 5.129e-210 687.0 2C4IS@1|root,2Z81U@2|Bacteria 2|Bacteria S Lantibiotic dehydratase, C terminus spaB - - ko:K20483 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - Lant_dehydr_C,Lant_dehydr_N DYD1_k127_5288865_2 765952.PUV_25140 1.21e-17 83.0 COG3328@1|root,COG3328@2|Bacteria,2JGVA@204428|Chlamydiae 204428|Chlamydiae L Transposase and inactivated derivatives - - - - - - - - - - - - Transposase_mut DYD1_k127_5288865_0 331113.SNE_B25180 8.452e-226 721.0 COG0457@1|root,COG0457@2|Bacteria 331113.SNE_B25180|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_5288865_3 331113.SNE_A04470 1.108e-08 57.0 2EJ2Y@1|root,33CU5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5298384_0 331113.SNE_A16910 5.15e-120 399.0 COG3491@1|root,COG3491@2|Bacteria,2JGE3@204428|Chlamydiae 204428|Chlamydiae C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N DYD1_k127_5302721_12 1444711.CCJF01000005_gene646 2.182e-57 206.0 COG1317@1|root,COG1317@2|Bacteria,2JG0V@204428|Chlamydiae 204428|Chlamydiae NU Type III yscL - - ko:K03223 ko03070,map03070 M00332,M00660 - - ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 - - FliH DYD1_k127_5302721_8 331113.SNE_A02900 4.592e-83 283.0 COG4790@1|root,COG4790@2|Bacteria,2JHI6@204428|Chlamydiae 204428|Chlamydiae U Type III secretion inner membrane protein SctR sctR - - ko:K03226 ko03070,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 - - FliP DYD1_k127_5302721_16 331113.SNE_A02890 3.399e-26 110.0 COG4794@1|root,COG4794@2|Bacteria,2JGCB@204428|Chlamydiae 204428|Chlamydiae U type III secretion inner membrane protein SctS sctS - - ko:K03227 ko03070,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 - - Bac_export_3 DYD1_k127_5302721_11 331113.SNE_A02880 3.17e-72 253.0 COG4791@1|root,COG4791@2|Bacteria,2JFXE@204428|Chlamydiae 204428|Chlamydiae U type III secretion inner membrane protein SctT sctT - - ko:K03228 ko03070,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 - - Bac_export_1 DYD1_k127_5302721_17 331113.SNE_A16530 3.709e-23 111.0 COG0457@1|root,COG0457@2|Bacteria 331113.SNE_A16530|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_5302721_13 331113.SNE_A01680 1.089e-40 160.0 COG0494@1|root,COG0494@2|Bacteria,2JH2H@204428|Chlamydiae 204428|Chlamydiae L nUDIX hydrolase - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX DYD1_k127_5302721_10 1437425.CSEC_2079 2.31e-75 265.0 COG0337@1|root,COG0337@2|Bacteria,2JFXP@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase DYD1_k127_5302721_2 331113.SNE_A11890 3.601e-158 509.0 COG0128@1|root,COG0128@2|Bacteria,2JG7W@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase DYD1_k127_5302721_15 331113.SNE_A11880 4.536e-29 123.0 COG0703@1|root,COG0703@2|Bacteria,2JGHA@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI DYD1_k127_5302721_1 331113.SNE_A11870 8.96e-163 519.0 COG0082@1|root,COG0082@2|Bacteria,2JFU7@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt DYD1_k127_5302721_3 331113.SNE_A02680 6.323e-137 446.0 COG0520@1|root,COG0520@2|Bacteria,2JFTA@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 DYD1_k127_5302721_9 1444711.CCJF01000005_gene632 3.083e-78 274.0 COG0719@1|root,COG0719@2|Bacteria,2JFQN@204428|Chlamydiae 204428|Chlamydiae O Uncharacterized protein family (UPF0051) sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 DYD1_k127_5302721_5 264201.pc0190 1.84e-98 326.0 COG0396@1|root,COG0396@2|Bacteria,2JFF7@204428|Chlamydiae 204428|Chlamydiae O ABC transporter sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran DYD1_k127_5302721_0 82654.Pse7367_1934 1.972e-229 717.0 COG0719@1|root,COG0719@2|Bacteria,1G0TH@1117|Cyanobacteria,1H8CG@1150|Oscillatoriales 1117|Cyanobacteria O COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 DYD1_k127_5302721_18 1158294.JOMI01000001_gene1499 5.472e-17 87.0 29F7N@1|root,3025B@2|Bacteria,4NNR8@976|Bacteroidetes,2G2G7@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - NfeD DYD1_k127_5302721_4 439235.Dalk_5076 7.418e-137 449.0 COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,42PJG@68525|delta/epsilon subdivisions,2WQ9J@28221|Deltaproteobacteria,2MMDR@213118|Desulfobacterales 28221|Deltaproteobacteria S Flotillin - - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot DYD1_k127_5302721_6 264201.pc1833 1.306e-92 312.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2JFD0@204428|Chlamydiae 204428|Chlamydiae L ATP dependent DNA ligase C terminal region - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N DYD1_k127_5302721_7 1444711.CCJF01000005_gene196 1.182e-87 299.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2JFD0@204428|Chlamydiae 204428|Chlamydiae L ATP dependent DNA ligase C terminal region - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N DYD1_k127_5302721_14 331113.SNE_A02590 2.355e-35 137.0 COG1088@1|root,COG1088@2|Bacteria,2JGKV@204428|Chlamydiae 204428|Chlamydiae M Male sterility protein rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD1_k127_5329196_5 1437425.CSEC_1444 2.618e-05 48.0 COG1887@1|root,COG1887@2|Bacteria,2JG2U@204428|Chlamydiae 204428|Chlamydiae M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf DYD1_k127_5329196_3 716544.wcw_1056 3.017e-78 274.0 COG0010@1|root,COG0010@2|Bacteria,2JG0D@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD1_k127_5329196_1 1124780.ANNU01000044_gene537 2.419e-132 433.0 COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,47K5F@768503|Cytophagia 976|Bacteroidetes Q PFAM Amidohydrolase family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 DYD1_k127_5329196_0 926569.ANT_31720 2.495e-227 717.0 COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi 200795|Chloroflexi E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N DYD1_k127_5329196_4 1163617.SCD_n02056 5.961e-67 235.0 COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria 28216|Betaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluF - 5.4.99.21 ko:K06182 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_5329196_2 459495.SPLC1_S411010 1.165e-95 329.0 COG0534@1|root,COG0534@2|Bacteria,1G2M4@1117|Cyanobacteria,1H8IY@1150|Oscillatoriales 1117|Cyanobacteria V Mate efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD1_k127_5365975_3 264201.pc0981 6.001e-15 75.0 COG0534@1|root,COG0534@2|Bacteria,2JFXX@204428|Chlamydiae 204428|Chlamydiae V MatE - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD1_k127_5365975_1 331113.SNE_A09680 3.659e-103 344.0 COG2220@1|root,COG2220@2|Bacteria,2JG2E@204428|Chlamydiae 204428|Chlamydiae S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 DYD1_k127_5365975_2 264201.pc1113 9.651e-41 158.0 COG0500@1|root,COG0500@2|Bacteria,2JGA0@204428|Chlamydiae 204428|Chlamydiae Q Histone methylation protein DOT1 - - - - - - - - - - - - DOT1,Methyltransf_31 DYD1_k127_5365975_0 331113.SNE_A09710 2.125e-119 389.0 COG0821@1|root,COG0821@2|Bacteria,2JFII@204428|Chlamydiae 204428|Chlamydiae I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE DYD1_k127_5369511_0 1173029.JH980292_gene2472 6.136e-153 499.0 COG0542@1|root,COG0542@2|Bacteria,1G0H1@1117|Cyanobacteria,1H96W@1150|Oscillatoriales 1117|Cyanobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB2 - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD1_k127_5369511_5 1444711.CCJF01000005_gene1759 1.415e-29 119.0 COG0227@1|root,COG0227@2|Bacteria,2JGBN@204428|Chlamydiae 204428|Chlamydiae J Ribosomal L28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 DYD1_k127_5369511_3 1444711.CCJF01000004_gene2452 4.397e-62 226.0 COG1502@1|root,COG1502@2|Bacteria,2JG2C@204428|Chlamydiae 204428|Chlamydiae I Phospholipase D family protein CP_0428 - - - - - - - - - - - PLDc_2 DYD1_k127_5369511_6 716544.wcw_0324 1.697e-29 130.0 COG1075@1|root,COG1075@2|Bacteria,2JGD8@204428|Chlamydiae 204428|Chlamydiae S Lipase (class 2) - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_5369511_4 331113.SNE_A17910 2.94e-56 202.0 COG2095@1|root,COG2095@2|Bacteria,2JG4G@204428|Chlamydiae 204428|Chlamydiae U UPF0056 inner membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD1_k127_5369511_2 331113.SNE_A17920 2.618e-63 224.0 COG0101@1|root,COG0101@2|Bacteria,2JG1S@204428|Chlamydiae 204428|Chlamydiae J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA2 - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 DYD1_k127_5369511_1 331113.SNE_A17930 3.171e-129 418.0 COG0024@1|root,COG0024@2|Bacteria,2JFE5@204428|Chlamydiae 204428|Chlamydiae E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24,SEC-C DYD1_k127_5413643_3 4113.PGSC0003DMT400043948 0.0005888 47.0 KOG0800@1|root,KOG0800@2759|Eukaryota,37JHM@33090|Viridiplantae,3GIAS@35493|Streptophyta,44JDG@71274|asterids 35493|Streptophyta O RING-type zinc-finger - GO:0003674,GO:0003824,GO:0004842,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0032446,GO:0036211,GO:0043161,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0061630,GO:0061659,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.27 ko:K19041 - - - - ko00000,ko01000,ko04121 - - - zf-RING_2 DYD1_k127_5413643_0 591158.SSMG_04325 1.052e-210 677.0 COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria 201174|Actinobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 DYD1_k127_5413643_1 716544.wcw_1229 4.816e-60 219.0 2C1EI@1|root,31PGH@2|Bacteria,2JG5Y@204428|Chlamydiae 204428|Chlamydiae - - CP_0278 - - - - - - - - - - - - DYD1_k127_5413643_2 765952.PUV_16690 3.192e-50 182.0 COG0621@1|root,COG0621@2|Bacteria,2JFUS@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine mtaB - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 DYD1_k127_5510491_9 420247.Msm_1289 1.049e-08 63.0 COG2246@1|root,arCOG02228@2157|Archaea,2Y20I@28890|Euryarchaeota,23PR3@183925|Methanobacteria 183925|Methanobacteria S PFAM GtrA-like protein - - - - - - - - - - - - GtrA DYD1_k127_5510491_1 1150621.SMUL_1619 1.374e-57 207.0 COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RMJ@68525|delta/epsilon subdivisions,2YMZV@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S PFAM SNARE associated Golgi protein dedA - - - - - - - - - - - SNARE_assoc DYD1_k127_5510491_6 1444711.CCJF01000005_gene1803 1.417e-26 109.0 COG2824@1|root,COG2824@2|Bacteria,2JGJ2@204428|Chlamydiae 204428|Chlamydiae P PhnA domain phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon DYD1_k127_5510491_3 234267.Acid_3421 3.677e-43 175.0 COG0791@1|root,COG0791@2|Bacteria,3Y5IG@57723|Acidobacteria 57723|Acidobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60,SPOR DYD1_k127_5510491_2 1410617.JHXH01000006_gene225 4.255e-47 187.0 COG2843@1|root,COG2843@2|Bacteria,1V20N@1239|Firmicutes,24AI2@186801|Clostridia,3WIG8@541000|Ruminococcaceae 186801|Clostridia M D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_M15_4 DYD1_k127_5510491_5 331113.SNE_A16070 8.332e-30 119.0 28X72@1|root,2ZJ5D@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5510491_0 479432.Sros_7423 2.714e-133 431.0 COG0596@1|root,COG0596@2|Bacteria,2I99I@201174|Actinobacteria,4EFS4@85012|Streptosporangiales 201174|Actinobacteria S Alpha/beta hydrolase family dhaA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009410,GO:0009987,GO:0016020,GO:0016787,GO:0016824,GO:0018786,GO:0019120,GO:0030312,GO:0042178,GO:0042197,GO:0042206,GO:0042221,GO:0044237,GO:0044248,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:1901575 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD1_k127_5510491_7 1347392.CCEZ01000014_gene2738 3.711e-21 98.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,36WMY@31979|Clostridiaceae 186801|Clostridia IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100,1.1.1.6 ko:K00059,ko:K22251 ko00061,ko00333,ko00561,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00561,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R01034,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_5524599_1 331113.SNE_B24500 2.87e-48 177.0 COG1538@1|root,COG1538@2|Bacteria,2JGB1@204428|Chlamydiae 204428|Chlamydiae MU Outer membrane efflux protein - - - - - - - - - - - - OEP DYD1_k127_5524599_2 6412.HelroP170916 8.061e-15 87.0 2FER8@1|root,2TG2D@2759|Eukaryota,3AU87@33154|Opisthokonta,3C3WC@33208|Metazoa 33208|Metazoa - - - - - - - - - - - - - - - DYD1_k127_5524599_0 45351.EDO35312 7.319e-99 335.0 28KU8@1|root,2QTAG@2759|Eukaryota,39UXQ@33154|Opisthokonta,3BUEB@33208|Metazoa 33208|Metazoa S STELLO glycosyltransferases - - - - - - - - - - - - STELLO DYD1_k127_5543177_6 1444711.CCJF01000005_gene210 1.867e-16 83.0 COG0811@1|root,COG0811@2|Bacteria,2JFXS@204428|Chlamydiae 204428|Chlamydiae U MotA TolQ ExbB proton channel family protein exbB - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB DYD1_k127_5543177_3 331113.SNE_A01680 2.153e-66 237.0 COG0494@1|root,COG0494@2|Bacteria,2JH2H@204428|Chlamydiae 204428|Chlamydiae L nUDIX hydrolase - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX DYD1_k127_5543177_4 251229.Chro_1455 1.373e-49 186.0 COG0596@1|root,COG0596@2|Bacteria,1GQ24@1117|Cyanobacteria 1117|Cyanobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_5543177_1 716544.wcw_0109 4.819e-96 320.0 COG0084@1|root,COG0084@2|Bacteria,2JFVX@204428|Chlamydiae 204428|Chlamydiae L TatD related DNase yabD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase DYD1_k127_5543177_2 716544.wcw_1784 1.887e-75 262.0 COG2009@1|root,COG2009@2|Bacteria,2JFCP@204428|Chlamydiae 204428|Chlamydiae C succinate dehydrogenase sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - - DYD1_k127_5543177_0 1444711.CCJF01000005_gene205 4.052e-140 447.0 COG1053@1|root,COG1053@2|Bacteria,2JFSU@204428|Chlamydiae 204428|Chlamydiae C succinate dehydrogenase sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_5615457_1 765952.PUV_22230 3.378e-58 213.0 COG0760@1|root,COG0760@2|Bacteria,2JG1Y@204428|Chlamydiae 204428|Chlamydiae O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - - - - - - - - - - Rotamase_2,SurA_N_3 DYD1_k127_5615457_0 1444711.CCJF01000004_gene1968 1.13e-113 379.0 COG0144@1|root,COG0144@2|Bacteria,2JFP8@204428|Chlamydiae 204428|Chlamydiae J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family rsmB - - - - - - - - - - - Methyltr_RsmB-F DYD1_k127_5615457_2 1123368.AUIS01000010_gene2379 5.577e-12 72.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane yqjF - - ko:K15977 - - - - ko00000 - - - DoxX DYD1_k127_5616825_5 1444712.BN1013_01644 1.454e-53 190.0 COG4974@1|root,COG4974@2|Bacteria,2JFEU@204428|Chlamydiae 204428|Chlamydiae D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_5616825_7 331113.SNE_A23420 5.601e-36 151.0 COG3468@1|root,COG3468@2|Bacteria,2JHAK@204428|Chlamydiae 204428|Chlamydiae MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - - DYD1_k127_5616825_1 1408444.JHYC01000008_gene1383 2.261e-138 453.0 COG0531@1|root,COG0531@2|Bacteria,1MUP1@1224|Proteobacteria,1RR0V@1236|Gammaproteobacteria,1JCZU@118969|Legionellales 118969|Legionellales E Amino acid permease - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 DYD1_k127_5616825_6 158190.SpiGrapes_2109 5.249e-52 193.0 COG1464@1|root,COG1464@2|Bacteria,2J5VI@203691|Spirochaetes 203691|Spirochaetes M Belongs to the nlpA lipoprotein family blpG - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 DYD1_k127_5616825_4 1444711.CCJF01000004_gene2034 3.015e-69 241.0 COG2011@1|root,COG2011@2|Bacteria,2JGUP@204428|Chlamydiae 204428|Chlamydiae P Binding-protein-dependent transport system inner membrane component - - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 DYD1_k127_5616825_2 574087.Acear_2067 3.743e-94 320.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3WA8U@53433|Halanaerobiales 186801|Clostridia P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL DYD1_k127_5616825_8 5888.CAK55755 2.137e-34 145.0 KOG0616@1|root,KOG0616@2759|Eukaryota,3ZB17@5878|Ciliophora 5878|Ciliophora T Protein kinase domain - - 2.7.11.11 ko:K04345 ko01522,ko04010,ko04014,ko04020,ko04024,ko04062,ko04113,ko04114,ko04138,ko04140,ko04211,ko04213,ko04261,ko04270,ko04310,ko04340,ko04341,ko04371,ko04530,ko04540,ko04611,ko04713,ko04714,ko04720,ko04723,ko04724,ko04725,ko04726,ko04727,ko04728,ko04740,ko04742,ko04750,ko04910,ko04911,ko04912,ko04913,ko04914,ko04915,ko04916,ko04918,ko04919,ko04921,ko04922,ko04923,ko04924,ko04925,ko04926,ko04927,ko04934,ko04961,ko04962,ko04970,ko04971,ko04976,ko05012,ko05020,ko05030,ko05031,ko05032,ko05110,ko05146,ko05165,ko05166,ko05169,ko05200,ko05203,ko05205,ko05414,map01522,map04010,map04014,map04020,map04024,map04062,map04113,map04114,map04138,map04140,map04211,map04213,map04261,map04270,map04310,map04340,map04341,map04371,map04530,map04540,map04611,map04713,map04714,map04720,map04723,map04724,map04725,map04726,map04727,map04728,map04740,map04742,map04750,map04910,map04911,map04912,map04913,map04914,map04915,map04916,map04918,map04919,map04921,map04922,map04923,map04924,map04925,map04926,map04927,map04934,map04961,map04962,map04970,map04971,map04976,map05012,map05020,map05030,map05031,map05032,map05110,map05146,map05165,map05166,map05169,map05200,map05203,map05205,map05414 M00695 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko03019,ko03036 - - - Pkinase DYD1_k127_5616825_3 331113.SNE_A20410 5.677e-83 283.0 COG1579@1|root,COG1579@2|Bacteria,2JFRJ@204428|Chlamydiae 204428|Chlamydiae S C4-type zinc ribbon domain CP_0228 - - ko:K07164 - - - - ko00000 - - - zf-RING_7 DYD1_k127_5616825_0 331113.SNE_A20270 1.387e-212 672.0 COG0112@1|root,COG0112@2|Bacteria,2JFEM@204428|Chlamydiae 204428|Chlamydiae E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT DYD1_k127_562589_1 3218.PP1S54_268V6.1 3.541e-07 63.0 COG2304@1|root,2QSCC@2759|Eukaryota,37KTA@33090|Viridiplantae,3G7B2@35493|Streptophyta 35493|Streptophyta S Inter-alpha-trypsin inhibitor heavy - - - - - - - - - - - - VWA_3 DYD1_k127_562589_0 331113.SNE_A01150 8.239e-88 319.0 COG0457@1|root,COG0457@2|Bacteria 331113.SNE_A01150|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_5674319_1 1444712.BN1013_01834 1.445e-68 244.0 COG0682@1|root,COG0682@2|Bacteria,2JFY9@204428|Chlamydiae 204428|Chlamydiae M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - - - - - - - - - - LGT DYD1_k127_5674319_2 765952.PUV_20180 1.051e-39 151.0 COG1576@1|root,COG1576@2|Bacteria,2JGAT@204428|Chlamydiae 204428|Chlamydiae J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase DYD1_k127_5674319_3 331113.SNE_A08420 2.024e-35 140.0 2BVXU@1|root,32V9S@2|Bacteria,2JGBD@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_5674319_0 331113.SNE_A08410 5.818e-125 409.0 COG4956@1|root,COG4956@2|Bacteria,2JFPK@204428|Chlamydiae 204428|Chlamydiae S TRAM domain - - - - - - - - - - - - TRAM DYD1_k127_5674319_4 1444711.CCJF01000005_gene1345 5.539e-07 52.0 COG0736@1|root,COG0736@2|Bacteria,2JGAG@204428|Chlamydiae 204428|Chlamydiae I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS DYD1_k127_5706590_2 9785.ENSLAFP00000028694 1.463e-08 66.0 COG4886@1|root,KOG4641@2759|Eukaryota,38CVU@33154|Opisthokonta,3B9XR@33208|Metazoa,3D07I@33213|Bilateria,487KK@7711|Chordata,4910F@7742|Vertebrata,3JFS0@40674|Mammalia,351SE@311790|Afrotheria 33208|Metazoa T Toll-like receptor 7 TLR7 GO:0000139,GO:0000323,GO:0001774,GO:0001775,GO:0001817,GO:0001819,GO:0001932,GO:0002218,GO:0002221,GO:0002224,GO:0002252,GO:0002253,GO:0002274,GO:0002376,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005768,GO:0005773,GO:0005774,GO:0005783,GO:0005789,GO:0005794,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0007249,GO:0007252,GO:0008144,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009612,GO:0009615,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010008,GO:0010556,GO:0010557,GO:0010604,GO:0010646,GO:0010647,GO:0012505,GO:0016020,GO:0016310,GO:0019220,GO:0019222,GO:0019538,GO:0023051,GO:0023052,GO:0023056,GO:0030139,GO:0031090,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0031399,GO:0031410,GO:0031982,GO:0031984,GO:0032009,GO:0032101,GO:0032103,GO:0032268,GO:0032479,GO:0032481,GO:0032642,GO:0032647,GO:0032648,GO:0032649,GO:0032675,GO:0032677,GO:0032722,GO:0032727,GO:0032728,GO:0032729,GO:0032755,GO:0032757,GO:0032991,GO:0034154,GO:0034162,GO:0035197,GO:0035556,GO:0036019,GO:0036020,GO:0036211,GO:0042035,GO:0042108,GO:0042116,GO:0042175,GO:0042325,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043235,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0045072,GO:0045078,GO:0045088,GO:0045089,GO:0045321,GO:0045335,GO:0045354,GO:0045356,GO:0045357,GO:0045359,GO:0045414,GO:0045416,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050727,GO:0050729,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0061900,GO:0061980,GO:0065007,GO:0071214,GO:0071260,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0080134,GO:0097159,GO:0097708,GO:0098542,GO:0098588,GO:0098791,GO:0098805,GO:0098827,GO:0098852,GO:0104004,GO:1901222,GO:1901224,GO:1901363,GO:1901564,GO:1902531,GO:1902533 - ko:K05404 ko04620,ko05162,ko05164,map04620,map05162,map05164 - - - ko00000,ko00001 - - - LRR_1,LRR_5,LRR_8,TIR DYD1_k127_5706590_1 1144275.COCOR_06542 4.281e-63 234.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria,2YUYT@29|Myxococcales 28221|Deltaproteobacteria E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD1_k127_5706590_0 2880.D7FSC6 1.355e-94 321.0 COG3239@1|root,2QQNB@2759|Eukaryota 2759|Eukaryota I oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water FAD2 GO:0000003,GO:0002376,GO:0003674,GO:0003824,GO:0004497,GO:0004768,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006950,GO:0006952,GO:0006955,GO:0007275,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016053,GO:0016215,GO:0016491,GO:0016705,GO:0016709,GO:0016717,GO:0016720,GO:0019752,GO:0030176,GO:0030497,GO:0031224,GO:0031227,GO:0031984,GO:0032501,GO:0032502,GO:0032787,GO:0033559,GO:0040002,GO:0040012,GO:0040017,GO:0042175,GO:0042335,GO:0042389,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045087,GO:0045485,GO:0046394,GO:0048518,GO:0048856,GO:0050183,GO:0050789,GO:0050896,GO:0055114,GO:0065007,GO:0071704,GO:0072330,GO:0098827,GO:1901576 1.14.18.4,1.14.19.16,1.14.19.22,1.14.19.25,1.14.19.33,1.14.19.34,1.14.19.35,1.14.19.36,1.14.19.6 ko:K10256,ko:K10257,ko:K21704,ko:K21710,ko:K21736 ko01040,ko01212,map01040,map01212 - R11043,R11044 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DUF3474,FA_desaturase DYD1_k127_5715530_5 444158.MmarC6_1662 1.226e-13 74.0 arCOG04882@1|root,arCOG04882@2157|Archaea,2Y4S5@28890|Euryarchaeota 28890|Euryarchaeota - - - - - - - - - - - - - - - DYD1_k127_5715530_3 351160.RCIX1527 1.152e-20 93.0 COG1476@1|root,arCOG01864@2157|Archaea,2Y089@28890|Euryarchaeota,2NA1I@224756|Methanomicrobia 224756|Methanomicrobia K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 DYD1_k127_5715530_2 1122165.AUHS01000006_gene579 1.786e-55 196.0 COG4954@1|root,COG4954@2|Bacteria,1N0G8@1224|Proteobacteria,1SAFD@1236|Gammaproteobacteria,1JDP2@118969|Legionellales 118969|Legionellales S Protein of unknown function (DUF2000) - - - - - - - - - - - - DUF2000 DYD1_k127_5715530_0 649747.HMPREF0083_02396 2.904e-79 269.0 COG1802@1|root,COG1802@2|Bacteria,1V3VV@1239|Firmicutes,4HI43@91061|Bacilli,27691@186822|Paenibacillaceae 91061|Bacilli K FCD - - - - - - - - - - - - FCD,GntR DYD1_k127_5715530_1 331113.SNE_A20610 5.215e-61 219.0 COG0789@1|root,COG0789@2|Bacteria 2|Bacteria K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding tipA - - ko:K21744 - - - - ko00000,ko03000 - - - MerR_1,TipAS DYD1_k127_5715530_4 765952.PUV_21700 8.87e-14 73.0 COG2334@1|root,COG2334@2|Bacteria,2JG0B@204428|Chlamydiae 204428|Chlamydiae S Phosphotransferase enzyme family - - - - - - - - - - - - APH DYD1_k127_5715530_6 264201.pc1205 1.164e-06 51.0 2CIK1@1|root,33PF6@2|Bacteria,2JGY5@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - AbiEi_2 DYD1_k127_5726225_7 643562.Daes_0075 3.159e-65 228.0 COG2605@1|root,COG2605@2|Bacteria,1QW1A@1224|Proteobacteria,42N0X@68525|delta/epsilon subdivisions,2WJYP@28221|Deltaproteobacteria,2MBCG@213115|Desulfovibrionales 28221|Deltaproteobacteria S GHMP kinases C terminal - - 2.7.1.168 ko:K07031 ko00540,map00540 - R09770 RC00002,RC00078 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD1_k127_5726225_1 41431.PCC8801_2379 1.882e-173 552.0 COG4976@1|root,COG4976@2|Bacteria,1G3BU@1117|Cyanobacteria,3KHKZ@43988|Cyanothece 1117|Cyanobacteria S C-methyltransferase C-terminal domain - - - - - - - - - - - - Methyltransf_13,Methyltransf_14,Methyltransf_23 DYD1_k127_5726225_3 391612.CY0110_27844 1.016e-128 417.0 COG0451@1|root,COG0451@2|Bacteria,1G40V@1117|Cyanobacteria,3KH4W@43988|Cyanothece 1117|Cyanobacteria GM RmlD substrate binding domain - - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase DYD1_k127_5726225_4 123214.PERMA_2004 6.913e-98 330.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,2G3NN@200783|Aquificae 200783|Aquificae M mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase - - 2.7.7.13,5.3.1.8 ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase DYD1_k127_5726225_2 868864.Dester_1365 1.104e-140 456.0 COG0438@1|root,COG0438@2|Bacteria,2G3UV@200783|Aquificae 200783|Aquificae M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_5726225_6 515635.Dtur_0347 4.962e-79 275.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_5726225_0 331113.SNE_A22780 0.0 1102.0 COG0550@1|root,COG0550@2|Bacteria,2JFEK@204428|Chlamydiae 204428|Chlamydiae L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - SWIB,Topoisom_bac,Toprim,zf-C4_Topoisom DYD1_k127_5726225_9 331113.SNE_A22740 1.068e-32 137.0 2AUH6@1|root,31K5F@2|Bacteria,2JG8C@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_5726225_5 1382359.JIAL01000001_gene1114 4.41e-82 282.0 2C1VH@1|root,2Z7Z3@2|Bacteria,3Y4CU@57723|Acidobacteria,2JJ58@204432|Acidobacteriia 204432|Acidobacteriia S 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - - - - - - - - - - Kdo_hydroxy DYD1_k127_5726225_8 765952.PUV_24250 1.8e-60 224.0 COG1508@1|root,COG1508@2|Bacteria,2JFWF@204428|Chlamydiae 204428|Chlamydiae K RNA polymerase rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD DYD1_k127_5726225_10 331113.SNE_A05850 1.472e-08 59.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_5742652_0 331113.SNE_A01000 2.97e-189 602.0 COG2804@1|root,COG2804@2|Bacteria,2JFKZ@204428|Chlamydiae 204428|Chlamydiae NU General secretion pathway protein E gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N DYD1_k127_5742652_1 331113.SNE_A01010 1.564e-84 294.0 COG1459@1|root,COG1459@2|Bacteria,2JFUD@204428|Chlamydiae 204428|Chlamydiae U General secretion pathway protein F gspF - - ko:K02455,ko:K02653 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSF DYD1_k127_5742652_2 1444711.CCJF01000005_gene539 2.064e-15 80.0 COG4968@1|root,COG4968@2|Bacteria,2JH2P@204428|Chlamydiae 204428|Chlamydiae NU Prepilin-type N-terminal cleavage methylation domain - - - - - - - - - - - - - DYD1_k127_5780824_0 716544.wcw_1572 2.405e-137 447.0 COG2204@1|root,COG2204@2|Bacteria,2JFQI@204428|Chlamydiae 204428|Chlamydiae T Sigma-54 dependent response regulator atoC - - ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5780824_2 1121106.JQKB01000028_gene4239 1.465e-07 53.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2JQ69@204441|Rhodospirillales 204441|Rhodospirillales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains flbD - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5780824_1 331113.SNE_A18980 8.837e-93 320.0 COG2604@1|root,COG2604@2|Bacteria,2JFK8@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function DUF115 - - - - - - - - - - - - MAF_flag10 DYD1_k127_5821784_1 1414720.CBYM010000031_gene2024 2.748e-27 116.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,36G3D@31979|Clostridiaceae 186801|Clostridia I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate - - 2.7.7.40,2.7.7.60 ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R02921,R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD,adh_short DYD1_k127_5821784_2 400682.PAC_15720573 4.381e-27 128.0 KOG0583@1|root,KOG0583@2759|Eukaryota,39IX8@33154|Opisthokonta,3BHY0@33208|Metazoa 33208|Metazoa T protein serine/threonine kinase activity - GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.11.1 ko:K08811 - - - - ko00000,ko01000,ko01001,ko03036 - - - Pkinase DYD1_k127_5821784_0 6669.EFX74573 1.802e-33 137.0 KOG0598@1|root,KOG0598@2759|Eukaryota,38BVS@33154|Opisthokonta,3B9HI@33208|Metazoa,3CTQR@33213|Bilateria,41UHG@6656|Arthropoda 33208|Metazoa T Serine/Threonine protein kinases, catalytic domain SGK1 GO:0000226,GO:0000902,GO:0001558,GO:0002028,GO:0002119,GO:0002164,GO:0003008,GO:0003013,GO:0003014,GO:0003096,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004712,GO:0005246,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005768,GO:0005769,GO:0005783,GO:0005789,GO:0005829,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006875,GO:0006883,GO:0006950,GO:0006952,GO:0006954,GO:0006974,GO:0006996,GO:0007010,GO:0007017,GO:0007019,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007492,GO:0007498,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007616,GO:0007632,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008217,GO:0008289,GO:0008306,GO:0008542,GO:0009314,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009755,GO:0009791,GO:0009888,GO:0009889,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010639,GO:0010646,GO:0010648,GO:0010720,GO:0010765,GO:0010769,GO:0010770,GO:0010941,GO:0010959,GO:0010975,GO:0010976,GO:0012505,GO:0014070,GO:0015459,GO:0015672,GO:0016020,GO:0016043,GO:0016247,GO:0016301,GO:0016310,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016773,GO:0017080,GO:0017081,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019222,GO:0019538,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022411,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030001,GO:0030003,GO:0030004,GO:0030030,GO:0030154,GO:0030182,GO:0030307,GO:0030334,GO:0031109,GO:0031110,GO:0031111,GO:0031113,GO:0031115,GO:0031175,GO:0031323,GO:0031326,GO:0031333,GO:0031344,GO:0031346,GO:0031410,GO:0031960,GO:0031974,GO:0031981,GO:0031982,GO:0031984,GO:0032271,GO:0032272,GO:0032409,GO:0032411,GO:0032501,GO:0032502,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032886,GO:0032984,GO:0032989,GO:0032990,GO:0033043,GO:0033554,GO:0033993,GO:0034220,GO:0035091,GO:0035556,GO:0036211,GO:0040008,GO:0040012,GO:0042127,GO:0042175,GO:0042221,GO:0042592,GO:0042981,GO:0042995,GO:0043005,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043269,GO:0043270,GO:0043401,GO:0043402,GO:0043412,GO:0043423,GO:0043434,GO:0043624,GO:0043933,GO:0044057,GO:0044058,GO:0044087,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045927,GO:0048037,GO:0048156,GO:0048382,GO:0048468,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048585,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048814,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050877,GO:0050890,GO:0050896,GO:0051046,GO:0051049,GO:0051050,GO:0051090,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051261,GO:0051270,GO:0051384,GO:0051493,GO:0051494,GO:0051716,GO:0051726,GO:0051960,GO:0051962,GO:0055037,GO:0055065,GO:0055067,GO:0055078,GO:0055080,GO:0055082,GO:0055085,GO:0060255,GO:0060284,GO:0060341,GO:0060453,GO:0060548,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070293,GO:0070294,GO:0070507,GO:0070887,GO:0071310,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0097435,GO:0097458,GO:0097708,GO:0098771,GO:0098772,GO:0098827,GO:0099106,GO:0120025,GO:0120035,GO:0120036,GO:0120039,GO:0140096,GO:1900006,GO:1901099,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901981,GO:1902903,GO:1902904,GO:1903506,GO:1903827,GO:1904375,GO:1904508,GO:1905475,GO:2000026,GO:2000112,GO:2000145,GO:2001141,GO:2001233,GO:2001234,GO:2001236,GO:2001237,GO:2001239,GO:2001240 2.7.11.1 ko:K13302,ko:K13303,ko:K13304 ko04068,ko04150,ko04151,ko04960,map04068,map04150,map04151,map04960 - - - ko00000,ko00001,ko01000,ko01001 - - - PX,Pkinase,Pkinase_C DYD1_k127_5894888_0 1444711.CCJF01000005_gene268 9.731e-85 286.0 COG1088@1|root,COG1088@2|Bacteria,2JGKV@204428|Chlamydiae 204428|Chlamydiae M Male sterility protein rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD1_k127_5894888_3 1444711.CCJF01000005_gene269 4.494e-51 194.0 COG1091@1|root,COG1091@2|Bacteria,2JG0H@204428|Chlamydiae 204428|Chlamydiae M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind DYD1_k127_5894888_1 264201.pc0124 7.115e-61 214.0 COG1898@1|root,COG1898@2|Bacteria,2JG3J@204428|Chlamydiae 204428|Chlamydiae M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose - - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom DYD1_k127_5894888_2 331113.SNE_A02560 1.895e-55 199.0 COG1496@1|root,COG1496@2|Bacteria,2JG1Z@204428|Chlamydiae 204428|Chlamydiae S Multi-copper polyphenol oxidoreductase laccase - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 DYD1_k127_5917282_1 290397.Adeh_0863 1.457e-45 177.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD1_k127_5967884_3 1005048.CFU_1424 1.369e-11 66.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,4728N@75682|Oxalobacteraceae 28216|Betaproteobacteria F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase DYD1_k127_5967884_0 1444711.CCJF01000005_gene1198 1.613e-137 444.0 COG2255@1|root,COG2255@2|Bacteria,2JFCF@204428|Chlamydiae 204428|Chlamydiae L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N DYD1_k127_5967884_1 331113.SNE_A14520 7.421e-98 334.0 COG2385@1|root,COG2385@2|Bacteria,2JG2X@204428|Chlamydiae 204428|Chlamydiae D Stage II sporulation protein - - - ko:K06381 - - - - ko00000 - - - SpoIID DYD1_k127_5967884_2 331113.SNE_A08610 3.977e-50 184.0 COG1694@1|root,COG3956@2|Bacteria,2JG6Q@204428|Chlamydiae 204428|Chlamydiae S MazG nucleotide pyrophosphohydrolase domain - - - ko:K02499 - - - - ko00000,ko03036 - - - MazG DYD1_k127_5981947_0 331113.SNE_A13180 1.728e-95 327.0 COG0389@1|root,COG0389@2|Bacteria,2JFG8@204428|Chlamydiae 204428|Chlamydiae L Domain of unknown function (DUF4113) umuC - - ko:K03502 - - - - ko00000,ko03400 - - - DUF4113,IMS,IMS_C DYD1_k127_5981947_1 269084.syc0007_d 8.5e-47 171.0 COG1974@1|root,COG1974@2|Bacteria,1G6T1@1117|Cyanobacteria,1H08K@1129|Synechococcus 1117|Cyanobacteria L Belongs to the peptidase S24 family umuD - - ko:K03503 - - - - ko00000,ko01000,ko01002,ko03400 - - - Peptidase_S24 DYD1_k127_5988425_0 331113.SNE_A01190 6.06e-77 269.0 COG0457@1|root,COG0457@2|Bacteria,2JFXG@204428|Chlamydiae 204428|Chlamydiae S Tetratricopeptide repeat CP_0145 - - - - - - - - - - - - DYD1_k127_5988425_1 1123228.AUIH01000092_gene552 2.754e-26 124.0 COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales 135619|Oceanospirillales G regulator of chromosome condensation, RCC1 - - - - - - - - - - - - - DYD1_k127_5988425_3 1444712.BN1013_01974 1.27e-16 89.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K03286,ko:K07275 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,PagL DYD1_k127_5988425_4 1352941.M877_26660 2.471e-05 55.0 COG3568@1|root,COG3568@2|Bacteria 2|Bacteria N Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - Exo_endo_phos DYD1_k127_5988429_1 716544.wcw_0665 1.378e-05 50.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_19,HTH_3 DYD1_k127_5988429_0 1437425.CSEC_2283 5.044e-121 424.0 COG3209@1|root,COG3409@1|root,COG3209@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein cwlK - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - PG_binding_1,Peptidase_M15_4,RHS_repeat DYD1_k127_5998153_4 716544.wcw_1226 3.117e-29 118.0 COG0621@1|root,COG0621@2|Bacteria,2JFWW@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 DYD1_k127_5998153_1 264201.pc1757 6.064e-53 190.0 COG0102@1|root,COG0102@2|Bacteria,2JGX6@204428|Chlamydiae 204428|Chlamydiae J Ribosomal protein L13 - - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 DYD1_k127_5998153_2 765952.PUV_08110 2.634e-47 173.0 COG0103@1|root,COG0103@2|Bacteria,2JG8N@204428|Chlamydiae 204428|Chlamydiae J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 DYD1_k127_5998153_3 331635.G5S_0391 6.662e-46 170.0 COG1607@1|root,COG1607@2|Bacteria 2|Bacteria I acyl-coa hydrolase yciA - - - - - - - - - - - 4HBT DYD1_k127_5998153_0 716544.wcw_0678 1.632e-158 514.0 COG2317@1|root,COG2317@2|Bacteria,2JFNU@204428|Chlamydiae 204428|Chlamydiae E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues - - 3.4.17.19 ko:K01299 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M32 DYD1_k127_5998153_5 331113.SNE_A17130 9.095e-22 106.0 29XK7@1|root,30JBA@2|Bacteria,2JG3A@204428|Chlamydiae 331113.SNE_A17130|- - - - - - - - - - - - - - - - DYD1_k127_6019082_1 1124780.ANNU01000044_gene487 1.603e-75 262.0 COG1063@1|root,COG1063@2|Bacteria,4P3W3@976|Bacteroidetes 976|Bacteroidetes E Glucose dehydrogenase C-terminus - - - - - - - - - - - - ADH_N,Glu_dehyd_C DYD1_k127_6019082_0 331113.SNE_A17730 4.096e-211 666.0 COG2303@1|root,COG2303@2|Bacteria,2JGPG@204428|Chlamydiae 204428|Chlamydiae E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N DYD1_k127_6019082_3 101852.XP_008086004.1 4.577e-05 51.0 KOG0800@1|root,KOG0800@2759|Eukaryota,39XDN@33154|Opisthokonta,3P1WN@4751|Fungi,3QPWY@4890|Ascomycota,20ZNP@147548|Leotiomycetes 4751|Fungi O Zinc finger, C3HC4 type (RING finger) - GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0016925,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019789,GO:0019941,GO:0030163,GO:0032446,GO:0036211,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0051603,GO:0061630,GO:0061659,GO:0061665,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.27 ko:K10631 - - - - ko00000,ko01000,ko03036,ko04121 - - - zf-C3HC4_3,zf-RING_2 DYD1_k127_6019082_5 1151122.AQYD01000004_gene2872 0.0001185 49.0 2DRD4@1|root,33B9X@2|Bacteria,2GTDE@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_6019082_2 331113.SNE_A08930 1.238e-42 162.0 COG0242@1|root,COG0242@2|Bacteria,2JG53@204428|Chlamydiae 204428|Chlamydiae J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD1_k127_6019082_4 331113.SNE_A08920 5.159e-05 46.0 COG1314@1|root,COG1314@2|Bacteria,2JGDG@204428|Chlamydiae 204428|Chlamydiae U Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG DYD1_k127_6040980_6 331113.SNE_A02330 2.116e-44 179.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - Wzy_C DYD1_k127_6040980_2 331113.SNE_A14190 3.708e-69 243.0 COG0500@1|root,COG2226@2|Bacteria,2JG4F@204428|Chlamydiae 204428|Chlamydiae H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran DYD1_k127_6040980_4 3659.XP_004138153.1 5.744e-56 207.0 COG0147@1|root,KOG1223@2759|Eukaryota,37NZG@33090|Viridiplantae,3G9ZX@35493|Streptophyta,4JKGM@91835|fabids 35493|Streptophyta E Isochorismate synthase ICS GO:0002376,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008152,GO:0008483,GO:0008909,GO:0009058,GO:0009108,GO:0009110,GO:0009266,GO:0009396,GO:0009409,GO:0009507,GO:0009536,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009627,GO:0009628,GO:0009696,GO:0009697,GO:0009814,GO:0009987,GO:0010118,GO:0010817,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0016853,GO:0016866,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0018958,GO:0019438,GO:0019752,GO:0019867,GO:0031090,GO:0031347,GO:0031348,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032787,GO:0034641,GO:0042180,GO:0042181,GO:0042372,GO:0042374,GO:0042398,GO:0042445,GO:0042446,GO:0042537,GO:0042558,GO:0042559,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045087,GO:0046189,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0048519,GO:0048583,GO:0048585,GO:0050486,GO:0050789,GO:0050832,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051707,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0080134,GO:0098542,GO:0098588,GO:0098805,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 5.4.4.2 ko:K02552,ko:K15040 ko00130,ko01053,ko01100,ko01110,ko01130,ko04020,ko04022,ko04216,ko04217,ko04218,ko04621,ko04979,ko05012,ko05016,ko05166,map00130,map01053,map01100,map01110,map01130,map04020,map04022,map04216,map04217,map04218,map04621,map04979,map05012,map05016,map05166 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000,ko02000,ko03029 1.B.8.1 - - Chorismate_bind,Porin_3 DYD1_k127_6040980_1 331113.SNE_A14210 1.616e-108 369.0 COG1165@1|root,COG1165@2|Bacteria,2JG2A@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_N DYD1_k127_6040980_7 595494.Tola_0432 3.64e-36 145.0 COG0596@1|root,COG0596@2|Bacteria,1R3WK@1224|Proteobacteria,1RQHH@1236|Gammaproteobacteria,1Y6P0@135624|Aeromonadales 135624|Aeromonadales H Serine aminopeptidase, S33 - - 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 DYD1_k127_6040980_0 324925.Ppha_2433 2.139e-142 458.0 COG0447@1|root,COG0447@2|Bacteria,1FDH0@1090|Chlorobi 1090|Chlorobi H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB - 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD1_k127_6040980_5 1227500.C494_17278 7.063e-45 174.0 COG1575@1|root,arCOG00480@2157|Archaea,2XT1M@28890|Euryarchaeota,23TNU@183963|Halobacteria 183963|Halobacteria H Belongs to the MenA family. Type 1 subfamily menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD1_k127_6040980_8 1028806.GGE_0957 6.721e-31 133.0 COG1441@1|root,COG1441@2|Bacteria,1MV33@1224|Proteobacteria,1RRC0@1236|Gammaproteobacteria,1Y77Z@135625|Pasteurellales 135625|Pasteurellales H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC - 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C DYD1_k127_6040980_3 519989.ECTPHS_00030 2.395e-61 225.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1WWI2@135613|Chromatiales 135613|Chromatiales IQ PFAM AMP-dependent synthetase and ligase - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C DYD1_k127_6050015_0 331113.SNE_A09800 4.132e-155 499.0 COG2256@1|root,COG2256@2|Bacteria,2JFSV@204428|Chlamydiae 204428|Chlamydiae L MgsA AAA+ ATPase C terminal rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N DYD1_k127_6050015_1 1293047.CBMA010000010_gene450 7.392e-73 251.0 COG0778@1|root,arCOG00288@2157|Archaea,2XTDP@28890|Euryarchaeota,23STU@183963|Halobacteria 183963|Halobacteria C COG0778 Nitroreductase - - - - - - - - - - - - Nitroreductase DYD1_k127_6050015_2 679926.Mpet_2335 1.518e-17 83.0 COG0531@1|root,arCOG00009@2157|Archaea,2XUU6@28890|Euryarchaeota,2NAJQ@224756|Methanomicrobia 224756|Methanomicrobia E PFAM amino acid permease-associated region - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 DYD1_k127_6093184_3 331113.SNE_A01160 1.062e-39 161.0 COG5599@1|root,COG5599@2|Bacteria 2|Bacteria T protein tyrosine phosphatase activity yopH GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0016020,GO:0019867,GO:0030100,GO:0030312,GO:0030313,GO:0031975,GO:0032879,GO:0044462,GO:0044464,GO:0045806,GO:0048519,GO:0048523,GO:0050764,GO:0050765,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0060627,GO:0065007,GO:0071944 - ko:K04055,ko:K13740 ko05100,ko05132,map05100,map05132 - - - ko00000,ko00001,ko02044 3.A.6.1 - - SicP-binding,Y_phosphatase,YopE,YopE_N,YopH_N DYD1_k127_6093184_4 765952.PUV_14160 6.229e-26 113.0 COG2259@1|root,COG2259@2|Bacteria,2JGCM@204428|Chlamydiae 204428|Chlamydiae S DoxX-like family - - - ko:K15977 - - - - ko00000 - - - DoxX DYD1_k127_6093184_0 1444711.CCJF01000004_gene2460 2.95e-138 448.0 COG0820@1|root,COG0820@2|Bacteria,2JFG3@204428|Chlamydiae 204428|Chlamydiae J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN2 - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM DYD1_k127_6093184_2 264201.pc1597 1.415e-53 196.0 COG0558@1|root,COG0558@2|Bacteria,2JFZD@204428|Chlamydiae 204428|Chlamydiae I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD1_k127_6093184_1 1444711.CCJF01000004_gene2371 2.895e-119 397.0 COG0297@1|root,COG0297@2|Bacteria,2JFIT@204428|Chlamydiae 204428|Chlamydiae F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 DYD1_k127_6121944_0 1121028.ARQE01000003_gene854 1.124e-65 243.0 COG0366@1|root,COG0366@2|Bacteria,1RB8E@1224|Proteobacteria 1224|Proteobacteria G trehalose synthase treS - - - - - - - - - - - Alpha-amylase DYD1_k127_6121944_1 331113.SNE_A05850 8.664e-44 170.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_6141888_3 331113.SNE_A08240 1.593e-09 59.0 COG1028@1|root,COG1028@2|Bacteria,2JFE8@204428|Chlamydiae 204428|Chlamydiae IQ Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_6141888_1 765952.PUV_09880 1.678e-90 308.0 COG0331@1|root,COG0331@2|Bacteria,2JFRU@204428|Chlamydiae 204428|Chlamydiae I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 DYD1_k127_6141888_0 331113.SNE_A08220 8.94e-137 442.0 COG0332@1|root,COG0332@2|Bacteria,2JFVI@204428|Chlamydiae 204428|Chlamydiae I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD1_k127_6141888_2 331113.SNE_A08180 7.528e-65 227.0 COG0353@1|root,COG0353@2|Bacteria,2JG40@204428|Chlamydiae 204428|Chlamydiae L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 DYD1_k127_6141888_4 1444711.CCJF01000005_gene1326 0.000946 44.0 COG4775@1|root,COG4775@2|Bacteria,2JFDS@204428|Chlamydiae 204428|Chlamydiae M membrane yaeT - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA DYD1_k127_6160844_2 561229.Dd1591_4242 6.028e-22 96.0 COG3645@1|root,COG3645@2|Bacteria,1MVMT@1224|Proteobacteria,1RYM2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA-damage-inducible protein d - - - ko:K14623 - - - - ko00000,ko03400 - - - Bro-N DYD1_k127_6160844_1 661367.LLO_2141 2.624e-54 205.0 COG1266@1|root,COG1266@2|Bacteria,1N3G9@1224|Proteobacteria,1T6YX@1236|Gammaproteobacteria,1JEJ0@118969|Legionellales 118969|Legionellales K CAAX protease self-immunity - - - - - - - - - - - - Abi,cNMP_binding DYD1_k127_6160844_0 1444711.CCJF01000004_gene2188 8.69e-87 298.0 COG1538@1|root,COG1538@2|Bacteria,2JFMS@204428|Chlamydiae 204428|Chlamydiae MU Outer membrane efflux protein - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - OEP DYD1_k127_6191369_2 716544.wcw_1797 5.679e-77 269.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2JFGW@204428|Chlamydiae 204428|Chlamydiae H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD1_k127_6191369_1 765952.PUV_01380 2.834e-122 400.0 COG0451@1|root,COG0451@2|Bacteria,2JFQM@204428|Chlamydiae 204428|Chlamydiae M Polysaccharide biosynthesis protein gAE4 - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd DYD1_k127_6191369_0 264201.pc0186 5.673e-127 415.0 COG1596@1|root,COG1596@2|Bacteria,2JFRQ@204428|Chlamydiae 204428|Chlamydiae M Polysaccharide biosynthesis/export protein wza - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB DYD1_k127_6191369_3 331113.SNE_A02320 3.492e-41 169.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2JFS4@204428|Chlamydiae 204428|Chlamydiae DM Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) wzc - - - - - - - - - - - - DYD1_k127_6197856_6 1162668.LFE_0989 2.774e-51 184.0 COG0114@1|root,COG0114@2|Bacteria,3J0FU@40117|Nitrospirae 40117|Nitrospirae C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 DYD1_k127_6197856_8 716544.wcw_1861 1.325e-42 159.0 2CTCU@1|root,32ST6@2|Bacteria,2JGAE@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_6197856_0 626522.GCWU000325_01158 9.938e-171 545.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,1WCXB@1283313|Alloprevotella 976|Bacteroidetes H Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N DYD1_k127_6197856_2 331113.SNE_A22470 1.65e-80 277.0 COG1162@1|root,COG1162@2|Bacteria,2JFKQ@204428|Chlamydiae 204428|Chlamydiae S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N DYD1_k127_6197856_7 331113.SNE_A22460 5.265e-51 190.0 COG0566@1|root,COG0566@2|Bacteria,2JG2I@204428|Chlamydiae 204428|Chlamydiae J SpoU rRNA Methylase family ysgA - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase DYD1_k127_6197856_5 204536.SULAZ_0882 2.208e-53 208.0 COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,2G3NC@200783|Aquificae 200783|Aquificae I PFAM AMP-dependent synthetase and ligase fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C,Acyltransferase,PP-binding DYD1_k127_6197856_10 1341181.FLJC2902T_06350 2.172e-12 72.0 COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,1I2UT@117743|Flavobacteriia,2NW1F@237|Flavobacterium 976|Bacteroidetes S thioesterase ybgC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 DYD1_k127_6197856_3 1122165.AUHS01000010_gene847 1.634e-74 264.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RW1Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria I acyl-CoA dehydrogenase atuD - - ko:K11731 ko00281,map00281 - R08089 RC01893 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_6197856_9 378806.STAUR_5619 3.459e-14 74.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2YVWU@29|Myxococcales 28221|Deltaproteobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD1_k127_6197856_4 331113.SNE_A22420 7.41e-70 257.0 COG2208@1|root,COG2208@2|Bacteria,2JGDN@204428|Chlamydiae 204428|Chlamydiae KT Stage II sporulation protein E (SpoIIE) rbsU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - Response_reg,SpoIIE DYD1_k127_6197856_1 331113.SNE_A22370 4.411e-118 392.0 COG0617@1|root,COG0617@2|Bacteria,2JFKF@204428|Chlamydiae 204428|Chlamydiae H polymerase pcnB_1 - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 DYD1_k127_6204504_2 1437425.CSEC_1816 3.055e-55 203.0 28N6X@1|root,2ZBBQ@2|Bacteria,2JFR2@204428|Chlamydiae 204428|Chlamydiae S Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_6204504_0 331113.SNE_A15330 4.4e-121 400.0 2DM90@1|root,327AV@2|Bacteria,2JGUS@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF1207) CP_0263 - - - - - - - - - - - DUF1207 DYD1_k127_6204504_1 1380391.JIAS01000020_gene1409 2.337e-73 259.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2JTAI@204441|Rhodospirillales 204441|Rhodospirillales E Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 DYD1_k127_6208812_0 331113.SNE_A20060 2.328e-116 389.0 COG0515@1|root,COG2208@1|root,COG0515@2|Bacteria,COG2208@2|Bacteria,2JFS0@204428|Chlamydiae 204428|Chlamydiae KLT Serine threonine protein kinase pkn5 - - - - - - - - - - - Pkinase,SpoIIE DYD1_k127_6208812_1 331113.SNE_A20110 9.255e-50 186.0 COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,2JFMB@204428|Chlamydiae 204428|Chlamydiae NU Bacterial type II and III secretion system protein sctC - - ko:K03219 ko03070,map03070 M00332,M00542 - - ko00000,ko00001,ko00002,ko02044 3.A.6.1,3.A.6.3 - - Secretin,Secretin_N DYD1_k127_6216937_2 1444711.CCJF01000005_gene1379 6.665e-58 203.0 COG1154@1|root,COG1154@2|Bacteria,2JFSC@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C DYD1_k127_6216937_3 264202.CF0697 2.806e-08 58.0 COG1722@1|root,COG1722@2|Bacteria 2|Bacteria L exodeoxyribonuclease VII activity xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S DYD1_k127_6216937_0 331113.SNE_A08900 6.792e-126 415.0 COG1570@1|root,COG1570@2|Bacteria,2JFHH@204428|Chlamydiae 204428|Chlamydiae L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 DYD1_k127_6216937_1 331113.SNE_A08910 6.109e-65 228.0 COG0149@1|root,COG0149@2|Bacteria,2JFXW@204428|Chlamydiae 204428|Chlamydiae F Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM DYD1_k127_6232508_12 716544.wcw_1478 2.152e-45 172.0 2A361@1|root,30RME@2|Bacteria,2JG3F@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_6232508_2 1444711.CCJF01000004_gene2009 1.803e-143 463.0 COG0057@1|root,COG0057@2|Bacteria,2JFDU@204428|Chlamydiae 204428|Chlamydiae G Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD1_k127_6232508_13 264201.pc0434 5.867e-43 161.0 COG0203@1|root,COG0203@2|Bacteria,2JG4B@204428|Chlamydiae 204428|Chlamydiae J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 DYD1_k127_6232508_1 331113.SNE_A21070 3.981e-163 520.0 COG0202@1|root,COG0202@2|Bacteria,2JFH2@204428|Chlamydiae 204428|Chlamydiae K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L DYD1_k127_6232508_10 1444712.BN1013_00994 3.184e-50 181.0 COG0100@1|root,COG0100@2|Bacteria,2JG17@204428|Chlamydiae 204428|Chlamydiae J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 DYD1_k127_6232508_9 716544.wcw_1483 2.665e-54 193.0 COG0099@1|root,COG0099@2|Bacteria,2JG65@204428|Chlamydiae 204428|Chlamydiae J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 DYD1_k127_6232508_0 331113.SNE_A21100 1.096e-210 662.0 COG0201@1|root,COG0201@2|Bacteria,2JFDR@204428|Chlamydiae 204428|Chlamydiae U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY DYD1_k127_6232508_14 331113.SNE_A21110 1.009e-38 149.0 COG0200@1|root,COG0200@2|Bacteria,2JG4Z@204428|Chlamydiae 204428|Chlamydiae J binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A DYD1_k127_6232508_5 331113.SNE_A21120 2.192e-68 235.0 COG0098@1|root,COG0098@2|Bacteria,2JG03@204428|Chlamydiae 204428|Chlamydiae J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C DYD1_k127_6232508_15 331113.SNE_A21130 5.818e-31 125.0 COG0256@1|root,COG0256@2|Bacteria,2JG9M@204428|Chlamydiae 204428|Chlamydiae J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p DYD1_k127_6232508_8 331113.SNE_A21140 6.494e-55 198.0 COG0097@1|root,COG0097@2|Bacteria,2JG2H@204428|Chlamydiae 204428|Chlamydiae J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 DYD1_k127_6232508_11 331113.SNE_A21150 4.966e-47 172.0 COG0096@1|root,COG0096@2|Bacteria,2JG30@204428|Chlamydiae 204428|Chlamydiae J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 DYD1_k127_6232508_4 765952.PUV_22890 5.947e-69 237.0 COG0094@1|root,COG0094@2|Bacteria,2JFGC@204428|Chlamydiae 204428|Chlamydiae J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C DYD1_k127_6232508_17 1444712.BN1013_00985 9.719e-23 100.0 COG0198@1|root,COG0198@2|Bacteria,2JGBU@204428|Chlamydiae 204428|Chlamydiae J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - ribosomal_L24 DYD1_k127_6232508_6 331113.SNE_A21180 4.315e-62 214.0 COG0093@1|root,COG0093@2|Bacteria,2JG1Q@204428|Chlamydiae 204428|Chlamydiae J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN - - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 DYD1_k127_6232508_16 643648.Slip_2228 1.559e-24 104.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,42K48@68298|Syntrophomonadaceae 186801|Clostridia J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 DYD1_k127_6232508_19 331113.SNE_A21200 7.591e-08 57.0 COG0255@1|root,COG0255@2|Bacteria,2JGHR@204428|Chlamydiae 204428|Chlamydiae J Belongs to the universal ribosomal protein uL29 family rpmC - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 DYD1_k127_6232508_7 1444712.BN1013_00981 1.578e-60 211.0 COG0197@1|root,COG0197@2|Bacteria,2JFZ1@204428|Chlamydiae 204428|Chlamydiae J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP - - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 DYD1_k127_6232508_3 1437425.CSEC_0220 1.479e-99 329.0 COG0092@1|root,COG0092@2|Bacteria,2JFW3@204428|Chlamydiae 204428|Chlamydiae J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C DYD1_k127_6232508_18 765952.PUV_22960 3.181e-12 67.0 COG0091@1|root,COG0091@2|Bacteria,2JG6V@204428|Chlamydiae 204428|Chlamydiae J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 DYD1_k127_6273217_3 264201.pc0137 2.998e-95 319.0 COG0264@1|root,COG0264@2|Bacteria,2JFNI@204428|Chlamydiae 204428|Chlamydiae J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD1_k127_6273217_2 1444711.CCJF01000005_gene253 1.081e-118 387.0 COG0052@1|root,COG0052@2|Bacteria,2JFQ4@204428|Chlamydiae 204428|Chlamydiae J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 DYD1_k127_6273217_0 1444711.CCJF01000005_gene255 7.122e-206 668.0 COG0768@1|root,COG0768@2|Bacteria,2JFNP@204428|Chlamydiae 204428|Chlamydiae M penicillin-binding protein pbp2 - - - - - - - - - - - PBP_dimer,Transpeptidase DYD1_k127_6273217_4 1444712.BN1013_00253 3.207e-27 116.0 COG0768@1|root,COG0768@2|Bacteria,2JFNP@204428|Chlamydiae 204428|Chlamydiae M penicillin-binding protein pbp2 - - - - - - - - - - - PBP_dimer,Transpeptidase DYD1_k127_6273217_1 596151.DesfrDRAFT_2342 2.904e-146 467.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,2M8B0@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM NAD-dependent epimerase dehydratase uxs - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD1_k127_6279690_2 880072.Desac_1403 6.656e-76 271.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,2MR7H@213462|Syntrophobacterales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07799 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_6279690_1 331113.SNE_A11240 1.832e-91 319.0 COG1538@1|root,COG1538@2|Bacteria,2JG63@204428|Chlamydiae 204428|Chlamydiae MU Outer membrane efflux protein - - - - - - - - - - - - OEP DYD1_k127_6279690_0 386456.JQKN01000007_gene3251 1.942e-147 479.0 arCOG02685@1|root,arCOG02685@2157|Archaea,2XV10@28890|Euryarchaeota 28890|Euryarchaeota G COG0477 Permeases of the major facilitator superfamily csbC - - - - - - - - - - - Sugar_tr DYD1_k127_6300813_2 1382306.JNIM01000001_gene876 2.063e-34 135.0 COG0384@1|root,COG0384@2|Bacteria,2G7RE@200795|Chloroflexi 200795|Chloroflexi S Phenazine biosynthesis-like protein - - - - - - - - - - - - PhzC-PhzF DYD1_k127_6300813_0 1313421.JHBV01000005_gene4520 2.843e-172 548.0 COG3825@1|root,COG3825@2|Bacteria,4NING@976|Bacteroidetes 976|Bacteroidetes S VWA domain containing CoxE-like protein - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE DYD1_k127_6300813_1 313606.M23134_02114 3.381e-67 231.0 COG0714@1|root,COG0714@2|Bacteria,4NIHM@976|Bacteroidetes,47P4K@768503|Cytophagia 976|Bacteroidetes O AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA,AAA_5 DYD1_k127_6330903_0 744980.TRICHSKD4_4228 2.658e-122 402.0 COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Filamentation induced by cAMP protein fic - - - - - - - - - - - - DUF4172,Fic DYD1_k127_634316_1 1444711.CCJF01000005_gene1429 4.891e-147 477.0 COG0488@1|root,COG0488@2|Bacteria,2JFI6@204428|Chlamydiae 204428|Chlamydiae S ABC transporter C-terminal domain - - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn DYD1_k127_634316_0 765952.PUV_07810 1.457e-152 489.0 COG0012@1|root,COG0012@2|Bacteria,2JFRS@204428|Chlamydiae 204428|Chlamydiae J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C DYD1_k127_634316_2 1238182.C882_1834 1.563e-14 77.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,2JQ8K@204441|Rhodospirillales 204441|Rhodospirillales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 DYD1_k127_6358577_0 264462.Bd1393 1.353e-12 79.0 COG4123@1|root,COG4123@2|Bacteria,1NS68@1224|Proteobacteria,42YVC@68525|delta/epsilon subdivisions,2MTQU@213481|Bdellovibrionales,2WTSQ@28221|Deltaproteobacteria 213481|Bdellovibrionales S Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - - - - - - - - - - - DYD1_k127_6358577_1 1201290.M902_0831 1.636e-12 79.0 COG2242@1|root,COG2242@2|Bacteria 2|Bacteria H protein methyltransferase activity - - 2.1.1.303,2.1.1.319 ko:K11434,ko:K20421 ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922 M00830 R10963,R11216,R11217,R11219 RC00003,RC00392,RC02120,RC03388,RC03390 ko00000,ko00001,ko00002,ko01000,ko03036 - - - DOT1,Methyltransf_11,Methyltransf_25 DYD1_k127_6381637_1 1437425.CSEC_2016 1.972e-41 156.0 COG3449@1|root,COG3449@2|Bacteria 2|Bacteria K DNA topoisomerase (ATP-hydrolyzing) inhibitor activity - - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18,SOUL DYD1_k127_6381637_0 765952.PUV_24000 1.19e-80 276.0 COG1741@1|root,COG1741@2|Bacteria 2|Bacteria O Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin DYD1_k127_640453_3 889378.Spiaf_1632 1.446e-17 83.0 COG0126@1|root,COG0126@2|Bacteria,2J68Y@203691|Spirochaetes 203691|Spirochaetes F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK DYD1_k127_640453_1 1444712.BN1013_00543 1.361e-32 133.0 2E6KG@1|root,33176@2|Bacteria,2JGF9@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_640453_0 331113.SNE_A22090 1.09e-101 336.0 COG2176@1|root,COG3530@1|root,COG2176@2|Bacteria,COG3530@2|Bacteria 2|Bacteria L Putative quorum-sensing-regulated virulence factor ypeB - 2.7.7.7 ko:K02342,ko:K03763,ko:K09954,ko:K10857 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - QSregVF_b,RNase_T DYD1_k127_640453_2 331113.SNE_A22080 1.949e-27 115.0 COG0218@1|root,COG0218@2|Bacteria,2JG1C@204428|Chlamydiae 204428|Chlamydiae D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 DYD1_k127_6409807_0 765952.PUV_03040 0.0 1122.0 COG0466@1|root,COG0466@2|Bacteria,2JFEC@204428|Chlamydiae 204428|Chlamydiae O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD1_k127_6409807_1 1444711.CCJF01000005_gene1417 1.263e-29 122.0 2BVXR@1|root,32IG2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DoxX DYD1_k127_6411026_4 289376.THEYE_A0933 5.998e-48 178.0 COG0329@1|root,COG0329@2|Bacteria,3J0CF@40117|Nitrospirae 40117|Nitrospirae E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD1_k127_6411026_6 553174.HMPREF0659_A6007 2.788e-05 56.0 COG2259@1|root,COG2259@2|Bacteria,4NK73@976|Bacteroidetes,2FVCZ@200643|Bacteroidia 976|Bacteroidetes S Doxx family - - - - - - - - - - - - - DYD1_k127_6411026_2 765952.PUV_00440 1.878e-78 272.0 COG5459@1|root,COG5459@2|Bacteria,2JG3Q@204428|Chlamydiae 204428|Chlamydiae J Mitochondrial small ribosomal subunit Rsm22 - - - - - - - - - - - - Rsm22 DYD1_k127_6411026_0 331113.SNE_A00610 1.828e-101 344.0 COG0477@1|root,COG2814@2|Bacteria,2JG4R@204428|Chlamydiae 2|Bacteria EGP Sugar (and other) transporter - - - ko:K08151,ko:K08153 - M00668,M00717 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8 - - MFS_1,Sugar_tr DYD1_k127_6411026_1 1444711.CCJF01000005_gene400 1.165e-85 290.0 COG0692@1|root,COG0692@2|Bacteria,2JFZR@204428|Chlamydiae 204428|Chlamydiae L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD1_k127_6411026_5 1444712.BN1013_00391 7.657e-29 118.0 2E89V@1|root,332NQ@2|Bacteria,2JGEW@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_6411026_3 1444711.CCJF01000005_gene184 1.294e-60 215.0 COG1472@1|root,COG1472@2|Bacteria,2JG4V@204428|Chlamydiae 204428|Chlamydiae G Glycosyl hydrolase family 3 N terminal domain ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 DYD1_k127_642501_0 56110.Oscil6304_0605 7.877e-116 394.0 COG5421@1|root,COG5421@2|Bacteria,1G02P@1117|Cyanobacteria,1HDCY@1150|Oscillatoriales 1117|Cyanobacteria L Domain of unknown function (DUF4277) - - - - - - - - - - - - DDE_Tnp_1,DUF4277 DYD1_k127_642501_1 1122165.AUHS01000028_gene1770 2.344e-28 114.0 COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,1JFCN@118969|Legionellales 118969|Legionellales L DDE_Tnp_1-associated - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_assoc DYD1_k127_6439000_0 331113.SNE_A02940 3.616e-88 301.0 COG1216@1|root,COG1216@2|Bacteria,2JFZ9@204428|Chlamydiae 204428|Chlamydiae S Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 DYD1_k127_6448734_1 331113.SNE_A18870 5.924e-30 120.0 COG5531@1|root,COG5531@2|Bacteria,2JGCA@204428|Chlamydiae 204428|Chlamydiae B SWI complex, BAF60b domains - - - - - - - - - - - - SWIB DYD1_k127_6448734_0 331113.SNE_A18850 1.575e-122 408.0 COG4284@1|root,COG4284@2|Bacteria,2JFIR@204428|Chlamydiae 204428|Chlamydiae G UTP--glucose-1-phosphate uridylyltransferase - - - - - - - - - - - - UDPGP DYD1_k127_6483698_4 331113.SNE_A06810 4.514e-21 97.0 COG0534@1|root,COG0534@2|Bacteria,2JFHM@204428|Chlamydiae 204428|Chlamydiae V MatE - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD1_k127_6483698_1 331113.SNE_A09660 4.856e-157 508.0 COG0205@1|root,COG0205@2|Bacteria,2JFH8@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfk - 2.7.1.90 ko:K00895 ko00010,ko00030,ko00051,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map01100,map01110,map01120,map01130 - R00764,R02073 RC00017 ko00000,ko00001,ko01000 - - - PFK DYD1_k127_6483698_0 1437425.CSEC_0827 1.337e-247 773.0 COG0504@1|root,COG0504@2|Bacteria,2JFCN@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase DYD1_k127_6483698_3 448385.sce4544 2.309e-21 99.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales 28221|Deltaproteobacteria J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX DYD1_k127_6483698_2 765952.PUV_16310 5.615e-97 322.0 COG0364@1|root,COG0364@2|Bacteria,2JFEN@204428|Chlamydiae 204428|Chlamydiae G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N DYD1_k127_6499845_1 765952.PUV_09000 1.467e-97 327.0 COG4974@1|root,COG4974@2|Bacteria,2JFCQ@204428|Chlamydiae 204428|Chlamydiae D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_6499845_0 331113.SNE_A11220 2.739e-309 977.0 COG0841@1|root,COG0841@2|Bacteria,2JFXK@204428|Chlamydiae 204428|Chlamydiae V AcrB/AcrD/AcrF family mdtB - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD1_k127_6502970_0 1380394.JADL01000001_gene2744 5.471e-146 472.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TRCN@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - - - - - - - - - - CTP_transf_like,PfkB DYD1_k127_6502970_1 187303.BN69_2082 4.961e-124 405.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_6502970_2 316055.RPE_1513 4.044e-92 310.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,3JTIE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_653744_3 653733.Selin_1194 7.551e-42 168.0 COG0503@1|root,COG0503@2|Bacteria 2|Bacteria F purine ribonucleoside salvage apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran DYD1_k127_653744_1 1173028.ANKO01000193_gene5880 4.414e-132 437.0 COG2303@1|root,COG2303@2|Bacteria,1G3V7@1117|Cyanobacteria,1H9T9@1150|Oscillatoriales 1117|Cyanobacteria E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N,NAD_binding_8 DYD1_k127_653744_5 388467.A19Y_2874 0.0003061 48.0 2DJZT@1|root,32UE2@2|Bacteria,1G8K4@1117|Cyanobacteria,1HCD2@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_653744_0 706587.Desti_3611 1.51e-134 451.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2MRZC@213462|Syntrophobacterales 28221|Deltaproteobacteria E TIGRFAM asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 DYD1_k127_653744_4 7897.ENSLACP00000004354 2.031e-21 104.0 COG1028@1|root,KOG1205@2759|Eukaryota,38GKD@33154|Opisthokonta,3BD72@33208|Metazoa,3CUAY@33213|Bilateria,480F1@7711|Chordata,499GG@7742|Vertebrata 33208|Metazoa Q NADP-retinol dehydrogenase activity RDH8 GO:0001523,GO:0001750,GO:0003008,GO:0003674,GO:0003824,GO:0004033,GO:0004745,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005929,GO:0006066,GO:0006629,GO:0006694,GO:0006720,GO:0006721,GO:0007600,GO:0007601,GO:0008106,GO:0008150,GO:0008152,GO:0008202,GO:0008610,GO:0009058,GO:0009987,GO:0010817,GO:0016020,GO:0016021,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0031224,GO:0031226,GO:0032501,GO:0034308,GO:0034754,GO:0042445,GO:0042572,GO:0042995,GO:0043005,GO:0043226,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044425,GO:0044441,GO:0044459,GO:0044463,GO:0044464,GO:0050877,GO:0050953,GO:0052650,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0097458,GO:0097730,GO:0097731,GO:0097733,GO:0120025,GO:0120038,GO:1901360,GO:1901362,GO:1901576,GO:1901615 - ko:K11150 ko00830,ko01100,map00830,map01100 - R08379 RC00649 ko00000,ko00001,ko01000 - - - adh_short DYD1_k127_653744_2 1265756.AWZW01000008_gene1121 1.842e-43 176.0 COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria 28211|Alphaproteobacteria H amine oxidase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 DYD1_k127_6578136_3 331113.SNE_A00890 9.362e-08 55.0 COG1887@1|root,COG1887@2|Bacteria,2JG2U@204428|Chlamydiae 204428|Chlamydiae M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf DYD1_k127_6578136_0 1444711.CCJF01000005_gene524 5.415e-98 330.0 COG1194@1|root,COG1194@2|Bacteria,2JFTR@204428|Chlamydiae 204428|Chlamydiae L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD,NUDIX_4 DYD1_k127_6578136_1 1123487.KB892857_gene2357 3.057e-54 205.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,2KWP5@206389|Rhodocyclales 206389|Rhodocyclales M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_6582392_1 331113.SNE_A18550 6.763e-84 283.0 COG0204@1|root,COG0204@2|Bacteria,2JFD3@204428|Chlamydiae 204428|Chlamydiae I Acyltransferase plsB - 2.3.1.15 ko:K00630 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_6582392_0 765952.PUV_02500 6.144e-167 551.0 COG1025@1|root,COG1025@2|Bacteria,2JFKH@204428|Chlamydiae 204428|Chlamydiae O insulinase family ide - 3.4.24.56 ko:K01408 ko05010,map05010 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M DYD1_k127_6664531_1 1444711.CCJF01000005_gene765 4.814e-166 533.0 COG1160@1|root,COG1160@2|Bacteria,2JFJG@204428|Chlamydiae 204428|Chlamydiae S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 DYD1_k127_6664531_0 1444712.BN1013_01380 0.0 1058.0 COG0553@1|root,COG0553@2|Bacteria,2JFGJ@204428|Chlamydiae 204428|Chlamydiae KL SNF2 family N-terminal domain CP_1034 - - - - - - - - - - - Helicase_C,SNF2_N,SWIM DYD1_k127_6709348_4 1408444.JHYC01000027_gene465 2.688e-11 73.0 COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1JCUV@118969|Legionellales 118969|Legionellales S Serine aminopeptidase, S33 mhpC - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 DYD1_k127_6709348_3 756272.Plabr_2565 1.116e-35 145.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11 DYD1_k127_6709348_2 1444712.BN1013_01102 1.16e-66 233.0 COG2148@1|root,COG2148@2|Bacteria,2JFX4@204428|Chlamydiae 204428|Chlamydiae M Bacterial sugar transferase wcaJ - - - - - - - - - - - Bac_transf DYD1_k127_6709348_1 264201.pc0550 4.94e-99 336.0 COG0845@1|root,COG0845@2|Bacteria,2JFGK@204428|Chlamydiae 204428|Chlamydiae M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 DYD1_k127_6709348_0 1288494.EBAPG3_390 3.6e-104 350.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,37207@32003|Nitrosomonadales 28216|Betaproteobacteria U AcrB/AcrD/AcrF family acrD - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD1_k127_6725767_4 716544.wcw_1732 0.0003134 46.0 COG1663@1|root,COG1663@2|Bacteria,2JFZS@204428|Chlamydiae 204428|Chlamydiae F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK DYD1_k127_6725767_1 331113.SNE_A03690 2.212e-139 453.0 COG0508@1|root,COG0508@2|Bacteria,2JGNQ@204428|Chlamydiae 204428|Chlamydiae C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bfmBB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_6725767_3 765952.PUV_06100 2.385e-56 203.0 COG0288@1|root,COG0288@2|Bacteria,2JGJ5@204428|Chlamydiae 204428|Chlamydiae P Reversible hydration of carbon dioxide cynT - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA DYD1_k127_6725767_2 331113.SNE_A16330 2.484e-109 361.0 COG1622@1|root,COG1622@2|Bacteria,2JFR4@204428|Chlamydiae 204428|Chlamydiae C COX Aromatic Rich Motif cyoA - 1.10.3.10 ko:K02297 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX2,COX_ARM DYD1_k127_6725767_0 331113.SNE_A16320 1.807e-299 925.0 COG0843@1|root,COG0843@2|Bacteria,2JFT7@204428|Chlamydiae 204428|Chlamydiae C Cytochrome C and Quinol oxidase polypeptide I cyoB - 1.10.3.10 ko:K02298 ko00190,ko01100,map00190,map01100 M00417 R11335 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.5 - - COX1 DYD1_k127_6737862_0 331113.SNE_A22620 9.573e-184 583.0 COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,2JFQE@204428|Chlamydiae 204428|Chlamydiae CE Belongs to the aldehyde dehydrogenase family putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh DYD1_k127_6737862_3 394221.Mmar10_0362 4.473e-23 106.0 COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,2UAQT@28211|Alphaproteobacteria,43XPM@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Phosphoglycerate mutase family protein - - - - - - - - - - - - His_Phos_1 DYD1_k127_6737862_2 648757.Rvan_2970 5.993e-79 271.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,3N8R9@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 DYD1_k127_6737862_1 331636.G5O_1037 1.066e-157 513.0 COG0210@1|root,COG0210@2|Bacteria,2JFDE@204428|Chlamydiae 204428|Chlamydiae L DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD1_k127_6747550_7 287.DR97_1722 9.822e-05 47.0 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1YHVZ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria U adhes_NPXG filamentous hemagglutinin family N-terminal domain protein Z012_01725 GO:0005575,GO:0005576 - - - - - - - - - - ESPR,Glug,Haemagg_act DYD1_k127_6747550_6 1116369.KB890024_gene3391 3.363e-51 207.0 COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,43IXV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O TIGRFAM outer membrane autotransporter barrel domain - - - - - - - - - - - - Autotransporter,PATR DYD1_k127_6747550_4 331113.SNE_A21880 7.372e-59 207.0 29TPM@1|root,30EXK@2|Bacteria,2JG4I@204428|Chlamydiae 204428|Chlamydiae S Belongs to the EUO family euo - - - - - - - - - - - HTH_17 DYD1_k127_6747550_1 331113.SNE_A21890 3.637e-238 753.0 COG0793@1|root,COG0793@2|Bacteria,2JFNQ@204428|Chlamydiae 204428|Chlamydiae M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,Peptidase_S41 DYD1_k127_6747550_0 1444712.BN1013_00519 1.772e-260 809.0 COG0008@1|root,COG0008@2|Bacteria,2JFU2@204428|Chlamydiae 204428|Chlamydiae J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c DYD1_k127_6747550_2 765952.PUV_01610 6.57e-97 328.0 COG0369@1|root,COG0369@2|Bacteria,2JFKP@204428|Chlamydiae 204428|Chlamydiae P sulfite reductase cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,NAD_binding_1 DYD1_k127_6747550_3 765952.PUV_01590 1.442e-67 235.0 COG0245@1|root,COG0245@2|Bacteria,2JG09@204428|Chlamydiae 204428|Chlamydiae I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB DYD1_k127_6747550_5 331113.SNE_A21990 5.179e-55 203.0 COG0027@1|root,COG0027@2|Bacteria,2JG5J@204428|Chlamydiae 204428|Chlamydiae F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - - - - - - - - - - - DYD1_k127_6747618_1 383372.Rcas_1169 5.639e-21 94.0 COG4113@1|root,COG4113@2|Bacteria,2G8Z6@200795|Chloroflexi 200795|Chloroflexi S Large family of predicted nucleotide-binding domains - - - - - - - - - - - - PIN DYD1_k127_6747618_0 868864.Dester_0328 1.511e-31 134.0 COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,2G44W@200783|Aquificae 200783|Aquificae M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR DYD1_k127_6747618_3 7091.BGIBMGA010238-TA 1.897e-07 53.0 COG0637@1|root,KOG2914@2759|Eukaryota,38XCG@33154|Opisthokonta,3BH1Y@33208|Metazoa,3CZHT@33213|Bilateria,41YP7@6656|Arthropoda,3SM0F@50557|Insecta,4484H@7088|Lepidoptera 33208|Metazoa S Haloacid dehalogenase-like hydrolase HDHD1 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009116,GO:0009163,GO:0009611,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042060,GO:0042578,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046134,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 3.1.3.96 ko:K17623 - - R11180 RC00017 ko00000,ko01000,ko01009 - - - HAD_2 DYD1_k127_678429_0 331113.SNE_A20010 2.985e-225 704.0 COG1157@1|root,COG1157@2|Bacteria,2JFQR@204428|Chlamydiae 204428|Chlamydiae NU Type III sctN - 3.6.3.14 ko:K03224 ko03070,map03070 M00332,M00542,M00660 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.6.1,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N DYD1_k127_678429_2 331113.SNE_A20020 6.061e-34 138.0 2FDSZ@1|root,31B3S@2|Bacteria,2JG7N@204428|Chlamydiae 204428|Chlamydiae S YscO-like protein - - - - - - - - - - - - YscO-like DYD1_k127_678429_1 331113.SNE_A20050 2.575e-58 216.0 COG1886@1|root,COG1886@2|Bacteria,2JG37@204428|Chlamydiae 204428|Chlamydiae N Type III flagellar switch regulator (C-ring) FliN C-term - - - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C DYD1_k127_678429_4 765952.PUV_05700 7.4e-11 65.0 COG0515@1|root,COG2208@1|root,COG0515@2|Bacteria,COG2208@2|Bacteria,2JH07@204428|Chlamydiae 204428|Chlamydiae KLT Serine threonine-protein kinase CP_0043 - - - - - - - - - - - Pkinase,SpoIIE DYD1_k127_6797259_0 331113.SNE_A05300 1.009e-108 362.0 COG0334@1|root,COG0334@2|Bacteria,2JFWZ@204428|Chlamydiae 204428|Chlamydiae C Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD1_k127_6797259_1 1444711.CCJF01000005_gene686 4.031e-101 334.0 28M7J@1|root,2ZAKZ@2|Bacteria,2JFRK@204428|Chlamydiae 204428|Chlamydiae S Protein of unknown function (DUF2709) CP_0089 - - - - - - - - - - - DUF2709 DYD1_k127_6797259_2 1444712.BN1013_00014 5.956e-27 115.0 COG0802@1|root,COG0802@2|Bacteria,2JG7U@204428|Chlamydiae 204428|Chlamydiae S Threonylcarbamoyl adenosine biosynthesis protein TsaE tsaE - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE DYD1_k127_6797259_3 331113.SNE_A22080 2.421e-11 65.0 COG0218@1|root,COG0218@2|Bacteria,2JG1C@204428|Chlamydiae 204428|Chlamydiae D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 DYD1_k127_6813881_1 264201.pc2013 9.512e-66 231.0 2CK4I@1|root,2ZBXP@2|Bacteria,2JFZG@204428|Chlamydiae 204428|Chlamydiae S Virulence plasmid protein pGP6-D-related protein CP_1067 - - - - - - - - - - - UPF0137 DYD1_k127_6813881_0 716544.wcw_0022 1.137e-138 454.0 COG0015@1|root,COG0015@2|Bacteria,2JFME@204428|Chlamydiae 204428|Chlamydiae F Adenylosuccinate lyase C-terminus purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 DYD1_k127_6813881_2 1279038.KB907347_gene3177 1.191e-05 54.0 2BHW6@1|root,32C03@2|Bacteria,1Q61N@1224|Proteobacteria,2VCAC@28211|Alphaproteobacteria,2JYAC@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD1_k127_6871449_0 1499680.CCFE01000033_gene3959 9.109e-87 295.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,1ZC2I@1386|Bacillus 91061|Bacilli P Sodium:sulfate symporter transmembrane region yflS - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp DYD1_k127_6871449_2 331113.SNE_A13570 1.96e-29 128.0 2DMAR@1|root,333GQ@2|Bacteria,2JHA0@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_6871449_1 88036.EFJ18204 7.555e-69 246.0 COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta 35493|Streptophyta C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD1_k127_687314_0 1280949.HAD_09775 1.525e-107 360.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S alcohol dehydrogenase - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N_2 DYD1_k127_689489_1 1444711.CCJF01000004_gene1960 1.512e-131 428.0 COG0587@1|root,COG0587@2|Bacteria,2JFDD@204428|Chlamydiae 204428|Chlamydiae L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity) dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP DYD1_k127_689489_0 297246.lpp2623 3.026e-195 617.0 COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria,1JDWR@118969|Legionellales 118969|Legionellales G Major Facilitator Superfamily uhpC - - ko:K07783 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.1.4.4,2.A.1.4.6 - - MFS_1 DYD1_k127_6927486_1 1306947.ARQD01000001_gene982 1.66e-43 165.0 COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria 2|Bacteria O Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 ko:K00384,ko:K03671,ko:K22345 ko00030,ko00450,ko04621,ko05418,map00030,map00450,map04621,map05418 - R01544,R02016,R03596,R09372 RC00013,RC00544,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 - - iNJ661.Rv3913,iPC815.YPO1374 Pyr_redox_2 DYD1_k127_6927486_0 331113.SNE_A10100 9.556e-110 377.0 COG3083@1|root,COG3083@2|Bacteria 2|Bacteria S sulfuric ester hydrolase activity yejM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07014 - - - - ko00000 - - - DUF3413,Sulfatase DYD1_k127_6933897_3 331113.SNE_A22050 1.232e-06 50.0 COG0334@1|root,COG0334@2|Bacteria,2JFWZ@204428|Chlamydiae 204428|Chlamydiae C Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD1_k127_6933897_0 331113.SNE_A22030 4.559e-232 731.0 COG0018@1|root,COG0018@2|Bacteria,2JFGE@204428|Chlamydiae 204428|Chlamydiae J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d DYD1_k127_6933897_1 1444711.CCJF01000005_gene679 3.117e-112 372.0 COG1509@1|root,COG1509@2|Bacteria,2JFD7@204428|Chlamydiae 204428|Chlamydiae C 4Fe-4S single cluster domain kamA - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Radical_SAM DYD1_k127_6933897_2 331113.SNE_A22000 3.679e-38 145.0 COG0766@1|root,COG0766@2|Bacteria,2JFIG@204428|Chlamydiae 204428|Chlamydiae M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase DYD1_k127_694650_2 765952.PUV_15200 2.032e-70 239.0 COG0346@1|root,COG0346@2|Bacteria,2JGH2@204428|Chlamydiae 204428|Chlamydiae E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_694650_0 765952.PUV_15190 5.786e-77 258.0 COG1673@1|root,COG1673@2|Bacteria,2JH4W@204428|Chlamydiae 204428|Chlamydiae S EVE domain - - - - - - - - - - - - EVE DYD1_k127_694650_1 765952.PUV_15180 1.36e-72 248.0 COG1846@1|root,COG1846@2|Bacteria,2JH1B@204428|Chlamydiae 204428|Chlamydiae K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR DYD1_k127_694650_4 86106.I862_01755 1.205e-42 160.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,NUDIX DYD1_k127_694650_3 1437425.CSEC_1415 3.137e-44 162.0 COG1619@1|root,COG1619@2|Bacteria 2|Bacteria V carboxypeptidase activity - - - - - - - - - - - - Peptidase_S66 DYD1_k127_6955230_10 765952.PUV_18820 3.755e-10 63.0 COG0216@1|root,COG0216@2|Bacteria,2JFRI@204428|Chlamydiae 204428|Chlamydiae J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD1_k127_6955230_6 716544.wcw_0694 3.675e-25 108.0 COG0254@1|root,COG0254@2|Bacteria,2JG9J@204428|Chlamydiae 204428|Chlamydiae J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 DYD1_k127_6955230_7 1437425.CSEC_0511 4.961e-25 114.0 COG0705@1|root,COG0705@2|Bacteria,2JG8J@204428|Chlamydiae 204428|Chlamydiae S Rhomboid family - - - - - - - - - - - - Rhomboid DYD1_k127_6955230_8 227086.JGI_V11_87202 8.826e-18 91.0 2E2B0@1|root,2S9J2@2759|Eukaryota 2759|Eukaryota S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 DYD1_k127_6955230_3 264201.pc1784 2.913e-49 184.0 COG1442@1|root,COG1442@2|Bacteria,2JG80@204428|Chlamydiae 204428|Chlamydiae M glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 DYD1_k127_6955230_9 1444711.CCJF01000005_gene1776 8.867e-15 78.0 COG0590@1|root,COG0590@2|Bacteria,2JGFE@204428|Chlamydiae 204428|Chlamydiae FJ tRNA wobble adenosine to inosine editing - - - - - - - - - - - - - DYD1_k127_6955230_2 1444712.BN1013_01577 2.642e-60 211.0 COG0590@1|root,COG0590@2|Bacteria,2JFZJ@204428|Chlamydiae 204428|Chlamydiae FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam DYD1_k127_6955230_5 1444711.CCJF01000005_gene1778 1.485e-40 157.0 2F34V@1|root,33TPV@2|Bacteria,2JGZC@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - - DYD1_k127_6955230_4 331113.SNE_A07500 2.681e-43 159.0 COG0184@1|root,COG0184@2|Bacteria,2JG4W@204428|Chlamydiae 204428|Chlamydiae J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 DYD1_k127_6955230_0 1444711.CCJF01000005_gene1781 8.121e-316 979.0 COG1185@1|root,COG1185@2|Bacteria,2JFFK@204428|Chlamydiae 204428|Chlamydiae J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 DYD1_k127_6955230_1 765952.PUV_24770 1.484e-130 422.0 COG0017@1|root,COG2606@1|root,COG0017@2|Bacteria,COG2606@2|Bacteria,2JGS0@204428|Chlamydiae 204428|Chlamydiae J Aminoacyl-tRNA editing domain - - 6.1.1.23 ko:K09759 ko00970,map00970 M00360 R03647,R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon,tRNA_edit DYD1_k127_6972711_2 1437425.CSEC_1546 3.356e-49 187.0 arCOG09486@1|root,32W31@2|Bacteria,2JGX5@204428|Chlamydiae 204428|Chlamydiae M Glycosyl transferase family 11 - - - - - - - - - - - - Glyco_transf_11 DYD1_k127_6972711_0 331113.SNE_A08660 0.0 2137.0 COG0178@1|root,COG0178@2|Bacteria,2JFSD@204428|Chlamydiae 204428|Chlamydiae L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD1_k127_6972711_1 1444711.CCJF01000004_gene2330 2.758e-195 621.0 COG0469@1|root,COG0469@2|Bacteria,2JFJH@204428|Chlamydiae 204428|Chlamydiae G Pyruvate kinase, barrel domain pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C DYD1_k127_6978098_1 903818.KI912268_gene1971 1.937e-26 112.0 COG3943@1|root,COG3943@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Virulence_RhuM DYD1_k127_6978098_0 1444711.CCJF01000005_gene923 1.534e-97 325.0 COG0596@1|root,COG0596@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds - - 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_717530_1 7739.XP_002589377.1 1.056e-22 108.0 COG4886@1|root,KOG0619@2759|Eukaryota,38E6Q@33154|Opisthokonta,3BE4G@33208|Metazoa,3D0J2@33213|Bilateria,483Q5@7711|Chordata 33154|Opisthokonta KLT maintenance of epithelial cell apical/basal polarity - - - - - - - - - - - - Death,LRR_4,LRR_8,Pkinase,Pkinase_Tyr,TIR_2 DYD1_k127_717530_0 331113.SNE_A07200 2.095e-193 616.0 COG0272@1|root,COG0272@2|Bacteria,2JFKS@204428|Chlamydiae 204428|Chlamydiae L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 DYD1_k127_73575_0 1158292.JPOE01000002_gene2649 5.406e-162 519.0 COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,2VJG9@28216|Betaproteobacteria,1KN7Z@119065|unclassified Burkholderiales 28216|Betaproteobacteria L Helix-turn-helix domain - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon DYD1_k127_73575_1 1122619.KB892295_gene2054 2.703e-42 156.0 COG1943@1|root,COG1943@2|Bacteria,1RDD7@1224|Proteobacteria,2VS0W@28216|Betaproteobacteria 28216|Betaproteobacteria L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp DYD1_k127_7608_0 264201.pc0640 6.427e-267 837.0 COG0465@1|root,COG0465@2|Bacteria,2JFFV@204428|Chlamydiae 204428|Chlamydiae D Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,Peptidase_M41 DYD1_k127_785236_0 331113.SNE_A05370 0.0 1082.0 COG2902@1|root,COG2902@2|Bacteria,2JFGR@204428|Chlamydiae 204428|Chlamydiae C Bacterial NAD-glutamate dehydrogenase gdhB - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,ELFV_dehydrog DYD1_k127_785236_3 756067.MicvaDRAFT_1856 0.0002033 49.0 2DRAG@1|root,33AYH@2|Bacteria,1GFJT@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_785236_2 331113.SNE_A06950 6.486e-05 56.0 COG0457@1|root,COG0457@2|Bacteria 331113.SNE_A06950|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_785236_1 331113.SNE_B25180 1.22e-58 226.0 COG0457@1|root,COG0457@2|Bacteria 331113.SNE_B25180|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_795317_0 264201.pc1877 4.13e-87 293.0 COG0528@1|root,COG0528@2|Bacteria,2JFZI@204428|Chlamydiae 204428|Chlamydiae F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD1_k127_795317_1 1444711.CCJF01000005_gene248 1.88e-57 205.0 COG0233@1|root,COG0233@2|Bacteria,2JFYW@204428|Chlamydiae 204428|Chlamydiae J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF DYD1_k127_804099_0 331113.SNE_A07690 1.054e-173 557.0 COG0507@1|root,COG0507@2|Bacteria,2JFJU@204428|Chlamydiae 204428|Chlamydiae L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 DYD1_k127_804099_1 1437425.CSEC_0908 1.297e-19 89.0 COG1961@1|root,COG1961@2|Bacteria,2JGRW@204428|Chlamydiae 204428|Chlamydiae L Resolvase, N terminal domain - - - - - - - - - - - - Resolvase,Zn_ribbon_recom DYD1_k127_811437_1 331113.SNE_A06750 6.882e-81 274.0 COG0664@1|root,COG1252@1|root,COG0664@2|Bacteria,COG1252@2|Bacteria,2JFCT@204428|Chlamydiae 2|Bacteria C Pyridine nucleotide-disulphide oxidoreductase ndh - 1.6.99.3 ko:K03885,ko:K10716 ko00190,map00190 - - - ko00000,ko00001,ko01000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Abhydrolase_6,CBS,Ion_trans,Pyr_redox_2,cNMP_binding DYD1_k127_811437_0 331113.SNE_A22950 1.625e-129 425.0 COG0814@1|root,COG0814@2|Bacteria,2JFWY@204428|Chlamydiae 204428|Chlamydiae E Tryptophan/tyrosine permease family - - - ko:K03834 - - - - ko00000,ko02000 2.A.42.1.1 - - Trp_Tyr_perm DYD1_k127_811437_2 331113.SNE_A22980 2.1e-22 99.0 COG0814@1|root,COG0814@2|Bacteria,2JFFY@204428|Chlamydiae 204428|Chlamydiae E Tryptophan/tyrosine permease family tyrP_1 - - ko:K03834 - - - - ko00000,ko02000 2.A.42.1.1 - - Trp_Tyr_perm DYD1_k127_833033_2 548479.HMPREF0573_11807 3.201e-13 75.0 COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4D34Y@85005|Actinomycetales 201174|Actinobacteria E Peptidase dimerization domain protein argE - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD1_k127_833033_1 768670.Calni_1985 1.707e-16 84.0 COG4866@1|root,COG4866@2|Bacteria,2GF8M@200930|Deferribacteres 200930|Deferribacteres S Uncharacterised conserved protein (DUF2156) - - - ko:K01163 - - - - ko00000 - - - DUF2156 DYD1_k127_833033_0 639282.DEFDS_0806 2.675e-37 145.0 COG4866@1|root,COG4866@2|Bacteria,2GF8M@200930|Deferribacteres 200930|Deferribacteres S Uncharacterised conserved protein (DUF2156) - - - ko:K01163 - - - - ko00000 - - - DUF2156 DYD1_k127_906891_1 331113.SNE_A15950 7.239e-149 492.0 COG0681@1|root,COG0681@2|Bacteria,2JFVN@204428|Chlamydiae 204428|Chlamydiae U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 DYD1_k127_906891_2 756272.Plabr_4457 1.969e-67 238.0 COG0451@1|root,COG0451@2|Bacteria,2IZ4B@203682|Planctomycetes 203682|Planctomycetes GM Vitamin K epoxide reductase family - - - - - - - - - - - - VKOR DYD1_k127_906891_4 344747.PM8797T_22873 5.139e-13 73.0 2E8F6@1|root,332TI@2|Bacteria,2J0NF@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - SPW DYD1_k127_906891_3 215803.DB30_8770 6.832e-51 186.0 COG0406@1|root,COG0406@2|Bacteria,1RCJE@1224|Proteobacteria,42W6J@68525|delta/epsilon subdivisions,2WSAJ@28221|Deltaproteobacteria,2YZEF@29|Myxococcales 28221|Deltaproteobacteria G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 DYD1_k127_906891_0 331113.SNE_A16000 0.0 1142.0 COG0060@1|root,COG0060@2|Bacteria,2JFQJ@204428|Chlamydiae 204428|Chlamydiae J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 DYD1_k127_923013_2 488538.SAR116_1163 5.274e-26 114.0 COG1268@1|root,COG1268@2|Bacteria,1RH78@1224|Proteobacteria,2U9DN@28211|Alphaproteobacteria,4BR35@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S BioY family bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY DYD1_k127_923013_3 1121104.AQXH01000001_gene2038 8.764e-11 71.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 DYD1_k127_923013_1 765952.PUV_13500 1.251e-30 125.0 COG1051@1|root,COG1051@2|Bacteria,2JHHF@204428|Chlamydiae 204428|Chlamydiae F NUDIX domain - - - - - - - - - - - - NUDIX DYD1_k127_923013_0 331113.SNE_A17070 1.127e-38 146.0 COG0304@1|root,COG0304@2|Bacteria,2JFJJ@204428|Chlamydiae 204428|Chlamydiae I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_932583_0 331113.SNE_A05620 5.832e-176 561.0 COG1252@1|root,COG1252@2|Bacteria,2JFCT@204428|Chlamydiae 204428|Chlamydiae C Pyridine nucleotide-disulphide oxidoreductase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_932583_2 1444712.BN1013_01669 6.693e-59 214.0 2A26P@1|root,30QHA@2|Bacteria,2JG3I@204428|Chlamydiae 204428|Chlamydiae - - - - - - - - - - - - - - SMI1_KNR4 DYD1_k127_932583_1 716544.wcw_1427 1.503e-133 432.0 COG1493@1|root,COG1493@2|Bacteria,2JFSZ@204428|Chlamydiae 204428|Chlamydiae H Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N DYD1_k127_975937_1 331113.SNE_A07810 7.579e-66 241.0 2BYJ1@1|root,32YU2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_975937_4 1201293.AKXQ01000001_gene2158 9.283e-21 93.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Cold shock cspG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD1_k127_975937_0 1123368.AUIS01000009_gene2470 3.719e-125 413.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - ko:K03309 - - - - ko00000 2.A.23 - - SDF DYD1_k127_975937_3 713587.THITH_15400 1.063e-29 123.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1SDVD@1236|Gammaproteobacteria,1WZPY@135613|Chromatiales 135613|Chromatiales S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 DYD1_k127_975937_2 1122164.JHWF01000012_gene2670 2.797e-35 145.0 COG4313@1|root,COG4313@2|Bacteria,1N5CH@1224|Proteobacteria,1SFFE@1236|Gammaproteobacteria,1JC64@118969|Legionellales 118969|Legionellales C Protein involved in meta-pathway of phenol degradation - - - - - - - - - - - - - ## 1389 queries scanned ## Total time (seconds): 10.45548939704895 ## Rate: 132.85 q/s