## Sun Mar 16 09:39:45 2025 ## emapper-2.1.9 ## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD1_bin.88.fa -m mmseqs --itype genome -o DYD1_bin.88 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD1_bin.88 --cpu 8 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs DYD1_k127_1019452_2 224911.27355053 8.26e-63 223.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,3JR3Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N DYD1_k127_1019452_1 404589.Anae109_4139 4.629e-108 355.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria 28221|Deltaproteobacteria L exodeoxyribonuclease III - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos DYD1_k127_1019452_0 1429916.X566_14165 8.41e-156 498.0 COG0655@1|root,COG0655@2|Bacteria,1MX6A@1224|Proteobacteria,2TU75@28211|Alphaproteobacteria,3JTKI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red DYD1_k127_1019452_3 1122915.AUGY01000118_gene6533 1.367e-48 188.0 COG0715@1|root,COG0715@2|Bacteria,1VRJ0@1239|Firmicutes,4HV8W@91061|Bacilli,26U3V@186822|Paenibacillaceae 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - DYD1_k127_1019452_4 65393.PCC7424_5738 8.992e-13 76.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,3KGJS@43988|Cyanothece 1117|Cyanobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_1021108_1 1267535.KB906767_gene2627 4.681e-157 509.0 COG0025@1|root,COG0025@2|Bacteria,3Y96Q@57723|Acidobacteria,2JNWA@204432|Acidobacteriia 2|Bacteria P Sodium/hydrogen exchanger family nhaP - - - - - - - - - - - Na_H_Exchanger DYD1_k127_1021108_3 479434.Sthe_1398 4.753e-70 240.0 COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,27XMB@189775|Thermomicrobia 189775|Thermomicrobia C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_1021108_0 234267.Acid_2226 2.491e-286 899.0 COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria 57723|Acidobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_1021108_2 272557.APE_2219 1.102e-78 276.0 COG1319@1|root,arCOG01926@2157|Archaea,2XQAN@28889|Crenarchaeota 28889|Crenarchaeota C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_104761_6 1122214.AQWH01000003_gene3922 4.439e-10 66.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria 1224|Proteobacteria P ABC-type Fe3 transport system, periplasmic component - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 DYD1_k127_104761_4 1231391.AMZF01000003_gene3114 3.782e-28 126.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_104761_3 933262.AXAM01000172_gene934 3.526e-29 117.0 COG2337@1|root,COG2337@2|Bacteria,1N1DE@1224|Proteobacteria,42WAI@68525|delta/epsilon subdivisions,2WRAJ@28221|Deltaproteobacteria,2MNJZ@213118|Desulfobacterales 28221|Deltaproteobacteria T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD1_k127_104761_1 1266914.ATUK01000005_gene2608 4.249e-79 280.0 COG1075@1|root,COG1075@2|Bacteria,1R5PF@1224|Proteobacteria,1S87U@1236|Gammaproteobacteria,1WZUV@135613|Chromatiales 135613|Chromatiales S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - DUF915,LCAT,PGAP1 DYD1_k127_104761_0 1123368.AUIS01000033_gene1370 7.756e-123 397.0 COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria 1224|Proteobacteria C domain, Protein - - - - - - - - - - - - Lactamase_B DYD1_k127_104761_5 1232410.KI421428_gene1203 6.694e-16 80.0 2EQIW@1|root,33I4X@2|Bacteria,1P5T0@1224|Proteobacteria,432D5@68525|delta/epsilon subdivisions,2WX86@28221|Deltaproteobacteria,43VTU@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_104761_2 671143.DAMO_1988 3.699e-42 159.0 COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria 2|Bacteria S Sulfatase-modifying factor enzyme 1 - - 1.14.99.50 ko:K18912 ko00340,map00340 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - FGE-sulfatase DYD1_k127_1061805_32 318996.AXAZ01000008_gene4295 2.971e-41 166.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_1061805_41 1198232.CYCME_2466 4.609e-08 59.0 COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Excisionase - - - - - - - - - - - - HTH_17 DYD1_k127_1061805_9 706587.Desti_4719 2.303e-136 447.0 COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales 28221|Deltaproteobacteria D Anion-transporting ATPase arsA - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase DYD1_k127_1061805_6 706587.Desti_4720 2.372e-144 466.0 COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales 28221|Deltaproteobacteria D Anion-transporting ATPase arsA - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase DYD1_k127_1061805_35 706587.Desti_4721 2.577e-33 132.0 2DZFA@1|root,32V98@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1061805_38 292459.STH682 3.546e-13 73.0 2DZFA@1|root,32V98@2|Bacteria,1VXNT@1239|Firmicutes,251ZR@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_1061805_7 706587.Desti_4722 4.725e-137 458.0 COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria 28221|Deltaproteobacteria T carbon starvation protein CstA cstA - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM DYD1_k127_1061805_27 211165.AJLN01000104_gene6534 4.963e-54 199.0 COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria,1JJCS@1189|Stigonemataceae 1117|Cyanobacteria J Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD1_k127_1061805_37 316067.Geob_3656 1.761e-13 74.0 COG3809@1|root,COG3809@2|Bacteria 2|Bacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - Rhomboid,zf-TFIIB DYD1_k127_1061805_19 889378.Spiaf_2345 1.9e-71 247.0 COG0066@1|root,COG0066@2|Bacteria,2JACS@203691|Spirochaetes 203691|Spirochaetes E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD1_k127_1061805_2 321332.CYB_0327 1.261e-211 665.0 COG0065@1|root,COG0065@2|Bacteria,1G1J0@1117|Cyanobacteria,1GZ9E@1129|Synechococcus 1117|Cyanobacteria H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase DYD1_k127_1061805_31 1123060.JONP01000009_gene2150 1.478e-43 170.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,2JQCA@204441|Rhodospirillales 204441|Rhodospirillales G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD1_k127_1061805_23 439235.Dalk_3493 1.996e-65 231.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MJMQ@213118|Desulfobacterales 28221|Deltaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 DYD1_k127_1061805_5 56780.SYN_00911 3.188e-145 468.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MQ48@213462|Syntrophobacterales 28221|Deltaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD1_k127_1061805_8 330214.NIDE1005 7.007e-137 447.0 COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae 40117|Nitrospirae C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD1_k127_1061805_3 1125863.JAFN01000001_gene2479 7.312e-189 605.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer DYD1_k127_1061805_24 443143.GM18_2609 1.074e-64 233.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,43SK7@69541|Desulfuromonadales 28221|Deltaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD1_k127_1061805_28 1187851.A33M_0648 1.468e-51 190.0 COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,3FDY8@34008|Rhodovulum 28211|Alphaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase DYD1_k127_1061805_4 289376.THEYE_A0653 5.306e-154 492.0 COG0059@1|root,COG0059@2|Bacteria,3J0DW@40117|Nitrospirae 40117|Nitrospirae H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN DYD1_k127_1061805_21 330214.NIDE0998 4.371e-71 243.0 COG0440@1|root,COG0440@2|Bacteria,3J0K8@40117|Nitrospirae 40117|Nitrospirae E ACT domain - - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C DYD1_k127_1061805_0 330214.NIDE0997 1.036e-272 851.0 COG0028@1|root,COG0028@2|Bacteria,3J0D6@40117|Nitrospirae 40117|Nitrospirae H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_1061805_29 498761.HM1_1718 2.768e-44 170.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia 186801|Clostridia O Universal bacterial protein YeaZ yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Acetyltransf_1,Peptidase_M22 DYD1_k127_1061805_12 1121405.dsmv_2170 4.261e-107 357.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2MIEV@213118|Desulfobacterales 28221|Deltaproteobacteria M SMART PDZ DHR GLGF domain protein rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 DYD1_k127_1061805_10 290512.Paes_0121 2.581e-131 429.0 COG0743@1|root,COG0743@2|Bacteria,1FD70@1090|Chlorobi 1090|Chlorobi I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom DYD1_k127_1061805_30 1232410.KI421418_gene2267 3.997e-44 173.0 COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2WQ6V@28221|Deltaproteobacteria,43SXU@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM phosphatidate cytidylyltransferase cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 DYD1_k127_1061805_17 439235.Dalk_3161 2.367e-76 265.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2WMWK@28221|Deltaproteobacteria,2MIZD@213118|Desulfobacterales 28221|Deltaproteobacteria I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD1_k127_1061805_26 706587.Desti_3975 6.895e-59 214.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2MRJU@213462|Syntrophobacterales 28221|Deltaproteobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF DYD1_k127_1061805_13 404380.Gbem_2754 3.076e-101 334.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD1_k127_1061805_15 370438.PTH_1253 9.854e-81 274.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,260PI@186807|Peptococcaceae 186801|Clostridia J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD1_k127_1061805_14 1121405.dsmv_2177 1.817e-90 304.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2MJCG@213118|Desulfobacterales 28221|Deltaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 DYD1_k127_1061805_1 880072.Desac_0681 5.647e-221 691.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,2MQ9T@213462|Syntrophobacterales 28221|Deltaproteobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind DYD1_k127_1061805_18 497964.CfE428DRAFT_0417 3.477e-73 260.0 COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia 74201|Verrucomicrobia J Responsible for synthesis of pseudouridine from uracil - - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_1061805_16 1121918.ARWE01000001_gene1843 1.511e-76 267.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,43S5P@69541|Desulfuromonadales 28221|Deltaproteobacteria H TIGRFAM riboflavin biosynthesis protein RibF ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase DYD1_k127_1061805_36 1121396.KB893092_gene3359 6.311e-30 132.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,2MISR@213118|Desulfobacterales 28221|Deltaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6 DYD1_k127_1061805_34 319225.Plut_0615 2.277e-34 139.0 COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi 1090|Chlorobi M PFAM OmpA MotB domain protein - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD1_k127_1061805_11 1232410.KI421422_gene2004 2.636e-109 370.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,43SB6@69541|Desulfuromonadales 28221|Deltaproteobacteria U TolB amino-terminal domain tolB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N DYD1_k127_1061805_40 264462.Bd0180 1.794e-08 65.0 COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,42XAV@68525|delta/epsilon subdivisions,2MTCM@213481|Bdellovibrionales,2WSJJ@28221|Deltaproteobacteria 213481|Bdellovibrionales M TonB family - - - ko:K03646,ko:K03832 - - - - ko00000,ko02000 2.C.1.1,2.C.1.2 - - TonB_2 DYD1_k127_1061805_33 243231.GSU0027 6.069e-37 144.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,43UY9@69541|Desulfuromonadales 28221|Deltaproteobacteria U PFAM Biopolymer transport protein ExbD TolR tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD DYD1_k127_1061805_22 1121918.ARWE01000001_gene3538 1.016e-66 235.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,43S1A@69541|Desulfuromonadales 28221|Deltaproteobacteria U MotA/TolQ/ExbB proton channel family aglX - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB DYD1_k127_1061805_25 215803.DB30_3033 4.722e-64 225.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,2YTW5@29|Myxococcales 28221|Deltaproteobacteria F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK DYD1_k127_10629_0 279714.FuraDRAFT_3442 1.775e-240 780.0 COG0744@1|root,COG0744@2|Bacteria,1NRPB@1224|Proteobacteria,2VJ7F@28216|Betaproteobacteria,2KSIX@206351|Neisseriales 206351|Neisseriales M Transglycosylase - - - - - - - - - - - - Transgly DYD1_k127_10629_4 1304275.C41B8_06502 8.964e-09 67.0 2C99D@1|root,2Z7Y8@2|Bacteria,1R5JY@1224|Proteobacteria,1SI3Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA-sulfur modification-associated - - - - - - - - - - - - DndB DYD1_k127_10629_2 383372.Rcas_2542 2.922e-62 218.0 2F76J@1|root,33ZMZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_10629_3 1231391.AMZF01000068_gene2180 9.064e-31 137.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_10629_1 1231391.AMZF01000063_gene1102 7.428e-147 485.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_10629_5 1301100.HG529264_gene679 7.489e-06 54.0 COG0662@1|root,COG0662@2|Bacteria,1VMRU@1239|Firmicutes,24Q2J@186801|Clostridia,36S43@31979|Clostridiaceae 186801|Clostridia G Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_10629_6 110662.Syncc9605_1079 4.817e-05 55.0 COG0715@1|root,COG0715@2|Bacteria,1G0PU@1117|Cyanobacteria,1GZ3S@1129|Synechococcus 1117|Cyanobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_1071791_0 671143.DAMO_1884 6.219e-113 370.0 COG3639@1|root,COG3639@2|Bacteria,2NPPG@2323|unclassified Bacteria 2|Bacteria U Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology phnE - 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - BPD_transp_1 DYD1_k127_1071791_1 671143.DAMO_1885 3.061e-82 282.0 COG3639@1|root,COG3639@2|Bacteria,2NPPG@2323|unclassified Bacteria 2|Bacteria U Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.6.1.63 ko:K02042,ko:K06162 ko00440,ko02010,map00440,map02010 M00223 R10186 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - BPD_transp_1 DYD1_k127_1071791_2 1382306.JNIM01000001_gene2693 1.66e-76 265.0 COG1319@1|root,COG1319@2|Bacteria,2G60Y@200795|Chloroflexi 200795|Chloroflexi C CO dehydrogenase flavoprotein domain protein - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_1071791_3 1034347.CAHJ01000048_gene232 5.047e-48 182.0 COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HC1W@91061|Bacilli,1ZC08@1386|Bacillus 91061|Bacilli C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_1072535_0 1379698.RBG1_1C00001G1237 1.45e-59 212.0 COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria 2|Bacteria T COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains zraR GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K02481,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_1072535_1 155864.EDL933_5335 5.425e-49 196.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSI4@1236|Gammaproteobacteria,3XPH1@561|Escherichia 1236|Gammaproteobacteria T Member of the two-component regulatory system ZraS ZraR. May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium zraS GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07709 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,sCache_3_2 DYD1_k127_1072535_2 1267534.KB906755_gene4178 1.44e-21 105.0 COG2885@1|root,COG2885@2|Bacteria,3Y3ZY@57723|Acidobacteria,2JI9Y@204432|Acidobacteriia 204432|Acidobacteriia M Belongs to the ompA family - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD1_k127_1180750_1 1380394.JADL01000009_gene3411 1.56e-27 126.0 COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2TWIP@28211|Alphaproteobacteria,2JQZZ@204441|Rhodospirillales 204441|Rhodospirillales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_1180750_0 1123504.JQKD01000049_gene2989 6.296e-58 218.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VRUP@28216|Betaproteobacteria,4AJ7Z@80864|Comamonadaceae 28216|Betaproteobacteria P Rieske [2Fe-2S] domain - - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_1189699_2 671143.DAMO_2372 6.559e-156 509.0 COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria 2|Bacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase DYD1_k127_1189699_7 935863.AWZR01000005_gene2248 1.138e-74 258.0 COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,1X60Y@135614|Xanthomonadales 135614|Xanthomonadales F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase DYD1_k127_1189699_9 396588.Tgr7_0319 9.325e-69 242.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1WX0V@135613|Chromatiales 135613|Chromatiales L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD1_k127_1189699_11 1089548.KI783301_gene3254 9.254e-57 209.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,3WERC@539002|Bacillales incertae sedis 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD DYD1_k127_1189699_5 1121918.ARWE01000001_gene1565 1.378e-109 364.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,43S66@69541|Desulfuromonadales 28221|Deltaproteobacteria J Glycoprotease family tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 DYD1_k127_1189699_24 1379698.RBG1_1C00001G0528 2.971e-08 64.0 COG0457@1|root,COG0457@2|Bacteria 1379698.RBG1_1C00001G0528|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_1189699_0 335543.Sfum_0290 8.721e-170 560.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MSIQ@213462|Syntrophobacterales 28221|Deltaproteobacteria M Transglycosylase mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H DYD1_k127_1189699_3 671143.DAMO_3115 3.213e-143 469.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf degP GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 DYD1_k127_1189699_20 880072.Desac_1279 4.383e-25 110.0 2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function (DUF1844) - - - - - - - - - - - - DUF1844 DYD1_k127_1189699_18 247490.KSU1_D0452 1.209e-33 143.0 COG0859@1|root,COG0859@2|Bacteria,2J4DC@203682|Planctomycetes 203682|Planctomycetes M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 DYD1_k127_1189699_4 1120973.AQXL01000119_gene531 4.295e-123 402.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,279A5@186823|Alicyclobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_1189699_6 243231.GSU0536 7.704e-91 306.0 COG1606@1|root,COG1606@2|Bacteria,1R7UZ@1224|Proteobacteria,42Q6V@68525|delta/epsilon subdivisions,2WKIM@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM asparagine synthase - - - ko:K06864 - - - - ko00000 - - - Asn_synthase,NAD_synthase,QueC DYD1_k127_1189699_13 697284.ERIC2_c38740 3.239e-54 199.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,26QP8@186822|Paenibacillaceae 91061|Bacilli I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD DYD1_k127_1189699_14 1278073.MYSTI_03019 7.198e-53 192.0 COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2YVAI@29|Myxococcales 28221|Deltaproteobacteria K Transcriptional regulator, CarD family - - - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF DYD1_k127_1189699_19 1120971.AUCA01000012_gene2558 8.247e-32 131.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,278GA@186823|Alicyclobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 DYD1_k127_1189699_17 391625.PPSIR1_08911 1.048e-36 156.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2X3DV@28221|Deltaproteobacteria,2YVMF@29|Myxococcales 28221|Deltaproteobacteria C 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_7 DYD1_k127_1189699_21 870187.Thini_2011 6.143e-23 100.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin DYD1_k127_1189699_15 104355.XP_007863184.1 6.871e-45 169.0 COG0237@1|root,KOG3220@2759|Eukaryota,38DFB@33154|Opisthokonta,3NWXJ@4751|Fungi,3V0FQ@5204|Basidiomycota,225ZM@155619|Agaricomycetes,3H48P@355688|Agaricomycetes incertae sedis 4751|Fungi H CoaE-domain-containing protein CAB5 GO:0000166,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005739,GO:0005783,GO:0005811,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990143 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE DYD1_k127_1189699_10 204669.Acid345_3606 4.977e-59 210.0 COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria,2JIEA@204432|Acidobacteriia 204432|Acidobacteriia J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase - - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD1_k127_1189699_1 344747.PM8797T_15421 3.194e-157 507.0 COG0334@1|root,COG0334@2|Bacteria,2IWWC@203682|Planctomycetes 203682|Planctomycetes C Belongs to the Glu Leu Phe Val dehydrogenases family - - - - - - - - - - - - ELFV_dehydrog,ELFV_dehydrog_N DYD1_k127_1189699_16 697281.Mahau_0719 1.871e-43 160.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,42GH7@68295|Thermoanaerobacterales 186801|Clostridia FG PFAM Histidine triad (HIT) protein hinT - - ko:K02503 - - - - ko00000,ko04147 - - - HIT DYD1_k127_1189699_22 1122134.KB893650_gene50 3.629e-22 100.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,1XM3X@135619|Oceanospirillales 135619|Oceanospirillales P Rieske 2Fe-2S - - - - - - - - - - - - Rieske DYD1_k127_1189699_23 159087.Daro_2008 1.156e-20 98.0 COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2VTX8@28216|Betaproteobacteria,2KWZ8@206389|Rhodocyclales 206389|Rhodocyclales P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske DYD1_k127_1189699_12 156889.Mmc1_3283 3.342e-56 206.0 COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Inositol monophosphatase suhB2 - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P DYD1_k127_1189699_8 269799.Gmet_2374 1.722e-70 244.0 COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,42TFN@68525|delta/epsilon subdivisions,2WP7M@28221|Deltaproteobacteria,43SNC@69541|Desulfuromonadales 28221|Deltaproteobacteria Q Isochorismatase family - - 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase DYD1_k127_1199585_3 574375.BAGA_24485 7.916e-42 166.0 COG1672@1|root,COG1672@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DM13 DYD1_k127_1199585_2 861299.J421_1880 4.119e-49 187.0 COG1672@1|root,COG1672@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DM13 DYD1_k127_1199585_0 861299.J421_1879 1.009e-166 535.0 COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes 2|Bacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_1199585_1 861299.J421_1872 1.353e-112 368.0 COG2303@1|root,COG2303@2|Bacteria 2|Bacteria E choline dehydrogenase activity - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N DYD1_k127_1215425_0 1521187.JPIM01000008_gene2096 1.139e-38 150.0 COG2250@1|root,COG2250@2|Bacteria 2|Bacteria S HEPN domain - - - - - - - - - - - - HEPN DYD1_k127_1215425_1 324602.Caur_3233 2.432e-32 131.0 COG1708@1|root,COG1708@2|Bacteria,2GB44@200795|Chloroflexi,377VQ@32061|Chloroflexia 32061|Chloroflexia S nucleotidyltransferase activity - - - - - - - - - - - - NTP_transf_2 DYD1_k127_1215425_3 1047013.AQSP01000127_gene479 9.558e-22 96.0 COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria 2|Bacteria L PFAM DNA methylase N-4 N-6 - - 2.1.1.72 ko:K00571,ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase DYD1_k127_1215425_4 46234.ANA_C10313 4.507e-15 82.0 COG2361@1|root,COG2361@2|Bacteria,1G7TP@1117|Cyanobacteria,1HNW6@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 DYD1_k127_1215425_2 395961.Cyan7425_1203 2.065e-29 120.0 COG1669@1|root,COG1669@2|Bacteria,1G7TF@1117|Cyanobacteria,3KIHZ@43988|Cyanothece 1117|Cyanobacteria L PFAM DNA polymerase beta domain protein region - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 DYD1_k127_1227907_6 1123371.ATXH01000002_gene359 4.187e-19 88.0 COG1758@1|root,COG1758@2|Bacteria,2GHZJ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 DYD1_k127_1227907_7 247490.KSU1_D0166 3.861e-08 56.0 COG0286@1|root,COG0286@2|Bacteria 2|Bacteria V site-specific DNA-methyltransferase (adenine-specific) activity - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase DYD1_k127_1227907_3 1173020.Cha6605_3962 8.695e-53 190.0 COG2346@1|root,COG2346@2|Bacteria 2|Bacteria O COG2346, Truncated hemoglobins glbN - - ko:K06886 - - - - ko00000 - - - Bac_globin DYD1_k127_1227907_0 1267534.KB906756_gene683 4.497e-116 382.0 COG1222@1|root,COG1222@2|Bacteria 2|Bacteria O protein catabolic process - - - ko:K03420,ko:K13525,ko:K17681 ko03050,ko04141,ko05134,map03050,map04141,map05134 M00343,M00400,M00403 - - ko00000,ko00001,ko00002,ko03019,ko03029,ko03051,ko04131,ko04147 3.A.16.1 - - AAA DYD1_k127_1227907_5 93220.LV28_02775 1.121e-32 138.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria,1K74B@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_1227907_4 509191.AEDB02000094_gene4226 1.757e-51 200.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,3WHRK@541000|Ruminococcaceae 186801|Clostridia EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1 DYD1_k127_1227907_2 338963.Pcar_2948 3.951e-58 215.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43T3R@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM peptidase S1 and S6, chymotrypsin Hap degQ - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_1227907_1 671143.DAMO_2601 8.542e-100 336.0 COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria 2|Bacteria C PFAM Alcohol dehydrogenase, zinc-binding - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_122916_0 387631.Asulf_01856 1.743e-109 379.0 COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota 28890|Euryarchaeota C aldehyde ferredoxin oxidoreductase - - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N DYD1_k127_122916_1 1122915.AUGY01000020_gene6479 1.111e-14 83.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_1245935_1 335543.Sfum_2657 6.214e-30 120.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,42PMH@68525|delta/epsilon subdivisions,2WKZU@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K07641,ko:K14980 ko02020,map02020 M00449,M00520 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,dCache_3 DYD1_k127_1245935_0 335543.Sfum_2433 1.556e-207 662.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42RS1@68525|delta/epsilon subdivisions,2WNR1@28221|Deltaproteobacteria,2MQVG@213462|Syntrophobacterales 28221|Deltaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - - - - - - - - - - Na_H_Exchanger,TrkA_N DYD1_k127_1245935_3 1122602.ATXP01000012_gene1733 3.865e-05 49.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,1W7UF@1268|Micrococcaceae 201174|Actinobacteria S PFAM aldo keto reductase - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red DYD1_k127_1245935_2 582899.Hden_1691 1.088e-28 117.0 COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,3N7N7@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 DYD1_k127_1257060_5 690850.Desaf_0463 1.078e-19 91.0 COG0457@1|root,COG0457@2|Bacteria 690850.Desaf_0463|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_1257060_0 1210884.HG799475_gene15269 6.93e-236 741.0 COG0033@1|root,COG0033@2|Bacteria,2IYG0@203682|Planctomycetes 203682|Planctomycetes G Phosphoglucomutase/phosphomannomutase, C-terminal domain - - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_1257060_1 378806.STAUR_5664 4.536e-127 436.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_1257060_3 1144310.PMI07_005447 2.759e-43 171.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_1257060_2 443152.MDG893_15387 1.802e-124 416.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD1_k127_1257060_4 2340.JV46_20180 2.798e-31 128.0 2C8PG@1|root,32RMK@2|Bacteria,1N0UQ@1224|Proteobacteria,1SBBP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1257060_6 32057.KB217478_gene4581 1.15e-16 82.0 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - AHSA1,HTH_20 DYD1_k127_1257060_8 1214065.BAGV01000115_gene1498 2.014e-06 51.0 2DR5Z@1|root,33ABB@2|Bacteria,1NIYJ@1224|Proteobacteria,1SGQ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_125877_1 502025.Hoch_5093 1.891e-26 116.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales 28221|Deltaproteobacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase DYD1_k127_125877_0 1231391.AMZF01000094_gene98 6.458e-38 158.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_1259203_24 1267533.KB906733_gene2954 6.502e-31 126.0 COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia 204432|Acidobacteriia I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS DYD1_k127_1259203_7 1123388.AQWU01000062_gene2195 3.117e-132 432.0 COG0683@1|root,COG0683@2|Bacteria,1WI02@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E ABC-type branched-chain amino acid transport - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_1259203_6 1499967.BAYZ01000016_gene6567 1.109e-136 445.0 COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria 2|Bacteria M Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477 Dala_Dala_lig_C,Dala_Dala_lig_N DYD1_k127_1259203_5 56780.SYN_00437 4.426e-140 456.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MQ7W@213462|Syntrophobacterales 28221|Deltaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin DYD1_k127_1259203_0 215803.DB30_7109 4.19e-183 582.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales 28221|Deltaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA DYD1_k127_1259203_25 1232410.KI421421_gene3868 1.045e-30 131.0 COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,43SIM@69541|Desulfuromonadales 28221|Deltaproteobacteria D POTRA domain, FtsQ-type ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 DYD1_k127_1259203_20 292459.STH1211 8.645e-73 256.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia 186801|Clostridia M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C DYD1_k127_1259203_2 316067.Geob_0781 8.003e-171 548.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,43T1G@69541|Desulfuromonadales 28221|Deltaproteobacteria M UDP-N-acetylmuramate-L-alanine ligase activity murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_1259203_13 246197.MXAN_5604 3.108e-100 337.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales 28221|Deltaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 DYD1_k127_1259203_11 1242864.D187_006399 1.841e-103 353.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales 28221|Deltaproteobacteria D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE DYD1_k127_1259203_9 269799.Gmet_0410 9.778e-128 422.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,43T3Z@69541|Desulfuromonadales 28221|Deltaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8 DYD1_k127_1259203_4 1121918.ARWE01000001_gene870 3.014e-142 464.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,43S7M@69541|Desulfuromonadales 28221|Deltaproteobacteria M Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - iAF987.Gmet_0409 Glycos_transf_4,MraY_sig1 DYD1_k127_1259203_14 404380.Gbem_0487 4.835e-100 345.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,43TX6@69541|Desulfuromonadales 28221|Deltaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_1259203_8 269799.Gmet_0407 3.538e-132 440.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,43T9W@69541|Desulfuromonadales 28221|Deltaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_1259203_3 338966.Ppro_3295 5.743e-168 555.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales 28221|Deltaproteobacteria M Penicillin-binding protein, dimerisation domain ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PASTA,PBP_dimer,Transpeptidase DYD1_k127_1259203_30 316067.Geob_0773 5.835e-09 61.0 COG3116@1|root,COG3116@2|Bacteria,1NKRZ@1224|Proteobacteria,42XDD@68525|delta/epsilon subdivisions,2WSII@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Cell division protein FtsL ftsL - - - - - - - - - - - DivIC,FtsL DYD1_k127_1259203_18 1048834.TC41_1193 1.209e-88 301.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,2797Y@186823|Alicyclobacillaceae 91061|Bacilli M Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 DYD1_k127_1259203_29 1220534.B655_1281 1.744e-12 72.0 COG1366@1|root,arCOG06891@2157|Archaea,2Y4H8@28890|Euryarchaeota 28890|Euryarchaeota T STAS domain - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS DYD1_k127_1259203_23 448385.sce1656 1.974e-33 134.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria,2YYCH@29|Myxococcales 28221|Deltaproteobacteria K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ DYD1_k127_1259203_22 644966.Tmar_2073 7.016e-40 153.0 COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia 186801|Clostridia L PFAM ribonuclease H rnhA - 3.1.26.4 ko:K03469,ko:K06864 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 DYD1_k127_1259203_26 1123371.ATXH01000020_gene478 2.242e-30 129.0 COG1579@1|root,COG1579@2|Bacteria,2GH3N@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S C4-type zinc ribbon domain - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 DYD1_k127_1259203_17 867903.ThesuDRAFT_01092 5.199e-89 311.0 COG0277@1|root,COG0277@2|Bacteria,1V135@1239|Firmicutes,24BZN@186801|Clostridia 186801|Clostridia C FAD linked oxidases, C-terminal domain - - 2.5.1.26 ko:K00803 ko00565,ko01100,ko04146,map00565,map01100,map04146 - R04311 RC00020,RC02886 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 DYD1_k127_1259203_1 290397.Adeh_3944 8.705e-174 555.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2YWVA@29|Myxococcales 28221|Deltaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD1_k127_1259203_21 1379698.RBG1_1C00001G1850 1.194e-56 209.0 COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria 2|Bacteria S Rhomboid family - - - - - - - - - - - - Rhomboid DYD1_k127_1259203_16 1120973.AQXL01000126_gene2925 1.089e-89 301.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,27878@186823|Alicyclobacillaceae 91061|Bacilli E ABC transporter livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD1_k127_1259203_19 926550.CLDAP_29810 4.656e-86 292.0 COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi 200795|Chloroflexi E PFAM ABC transporter related - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_1259203_10 1444309.JAQG01000019_gene533 2.453e-120 400.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HDIU@91061|Bacilli,274EW@186822|Paenibacillaceae 91061|Bacilli E Branched-chain amino acid transport system / permease component livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_1259203_12 1042163.BRLA_c004990 2.796e-101 339.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,26URK@186822|Paenibacillaceae 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_1259203_28 316067.Geob_2842 4.683e-19 103.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria,43S2F@69541|Desulfuromonadales 28221|Deltaproteobacteria M AsmA-like C-terminal region - - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2,DUF748 DYD1_k127_1259203_15 472759.Nhal_3155 2.042e-97 337.0 COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales 135613|Chromatiales K ribonuclease BN - - - ko:K07058 - - - - ko00000 - - - Rrf2,Virul_fac_BrkB DYD1_k127_1259203_27 485916.Dtox_2231 1.929e-20 106.0 28P53@1|root,2ZC07@2|Bacteria,1VNRW@1239|Firmicutes,24ZF8@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_1260030_2 1410665.JNKR01000001_gene605 5.462e-10 70.0 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4H33K@909932|Negativicutes 909932|Negativicutes S CBS domain acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS DYD1_k127_1260030_1 986075.CathTA2_1237 1.37e-13 81.0 COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli 91061|Bacilli S CoA-binding protein yneT - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 DYD1_k127_1260030_0 864069.MicloDRAFT_00047140 5.803e-69 241.0 COG0392@1|root,COG0392@2|Bacteria,1MXH9@1224|Proteobacteria,2U1DX@28211|Alphaproteobacteria,1JRDH@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_1270164_1 1501230.ET33_19345 2.087e-118 387.0 COG0667@1|root,COG0667@2|Bacteria,1V300@1239|Firmicutes,4HERM@91061|Bacilli,26TBI@186822|Paenibacillaceae 91061|Bacilli C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD1_k127_1270164_2 469383.Cwoe_4082 7.101e-114 375.0 COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CRBS@84995|Rubrobacteria 84995|Rubrobacteria C PFAM Transketolase central region - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_1270164_3 469383.Cwoe_4083 1.167e-111 370.0 COG1071@1|root,COG1071@2|Bacteria,2HVS4@201174|Actinobacteria 201174|Actinobacteria C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD1_k127_1270164_4 469383.Cwoe_4080 3.921e-111 368.0 COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria 2|Bacteria C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit - - 1.2.4.1,1.2.4.4 ko:K00162,ko:K11381 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,E1_dh,Transket_pyr,Transketolase_C DYD1_k127_1270164_5 469383.Cwoe_4081 8.205e-89 304.0 COG1071@1|root,COG1071@2|Bacteria,2IC03@201174|Actinobacteria,4CQ7Q@84995|Rubrobacteria 84995|Rubrobacteria C PFAM dehydrogenase, E1 component - - - ko:K21416 - - - - ko00000,ko01000 - - - E1_dh DYD1_k127_1270164_6 935840.JAEQ01000004_gene646 8.779e-18 95.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_1270164_0 1173024.KI912148_gene3045 9.381e-157 500.0 COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1JIY9@1189|Stigonemataceae 1117|Cyanobacteria S Alcohol dehydrogenase GroES-like domain - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_1271865_4 1190606.AJYG01000182_gene1917 3.774e-13 72.0 COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XT8K@135623|Vibrionales 135623|Vibrionales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids - - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Cauli_VI,RNase_H DYD1_k127_1271865_2 43989.cce_0954 2.485e-18 95.0 2BWMX@1|root,2ZIUW@2|Bacteria,1G304@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_1271865_0 1521187.JPIM01000022_gene637 8.851e-110 359.0 COG4422@1|root,COG4422@2|Bacteria,2G7TP@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF5131 DYD1_k127_1271865_5 290317.Cpha266_2131 8.049e-12 69.0 COG1943@1|root,COG1943@2|Bacteria 290317.Cpha266_2131|- L Transposase - - - - - - - - - - - - - DYD1_k127_1271865_3 1126627.BAWE01000002_gene553 1.21e-15 79.0 2BUZT@1|root,32QCC@2|Bacteria,1Q8TE@1224|Proteobacteria,2UYDE@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1271865_1 649638.Trad_1402 4.198e-52 187.0 COG1848@1|root,COG1848@2|Bacteria 2|Bacteria G Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07064 - - - - ko00000 - - - PIN DYD1_k127_1275324_6 68170.KL590490_gene1015 2.471e-14 83.0 COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria,4E4EM@85010|Pseudonocardiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_1275324_10 797114.C475_16196 2.95e-07 61.0 COG0346@1|root,arCOG02708@2157|Archaea,2XWTX@28890|Euryarchaeota,23VNA@183963|Halobacteria 183963|Halobacteria E Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD1_k127_1275324_7 391038.Bphy_0955 8.508e-14 82.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,1K2JX@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM NMT1 THI5 like domain protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 DYD1_k127_1275324_1 1040989.AWZU01000035_gene1778 2.37e-117 393.0 COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,3JW76@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD1_k127_1275324_2 640081.Dsui_2768 9.641e-87 301.0 COG2982@1|root,COG2982@2|Bacteria,1NBZ0@1224|Proteobacteria,2VPGQ@28216|Betaproteobacteria,2KVEP@206389|Rhodocyclales 206389|Rhodocyclales M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748 DYD1_k127_1275324_0 330214.NIDE3623 7.135e-129 416.0 COG0656@1|root,COG0656@2|Bacteria 2|Bacteria S aldo-keto reductase (NADP) activity ytbE - - - - - - - - - - - Aldo_ket_red,DUF4157 DYD1_k127_1275324_5 935839.JAGJ01000013_gene2847 9.589e-17 90.0 COG1262@1|root,COG1262@2|Bacteria,2H7FI@201174|Actinobacteria,4F5DD@85017|Promicromonosporaceae 201174|Actinobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase DYD1_k127_1275324_9 1078085.HMPREF1210_01952 6.95e-08 64.0 COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,4HHFE@91061|Bacilli 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_1275324_3 1121106.JQKB01000005_gene2135 7.625e-46 174.0 COG0725@1|root,COG0725@2|Bacteria 2|Bacteria P tungstate binding - - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 DYD1_k127_1275324_8 1123242.JH636434_gene4888 2.549e-13 72.0 COG5487@1|root,COG5487@2|Bacteria,2J16P@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF1328) - - - - - - - - - - - - DUF1328 DYD1_k127_1275324_4 504472.Slin_2519 9.012e-18 90.0 COG3386@1|root,COG3386@2|Bacteria,4NS13@976|Bacteroidetes,47UF3@768503|Cytophagia 976|Bacteroidetes G SMP-30/Gluconolaconase/LRE-like region - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD1_k127_1275324_11 891968.Anamo_1078 2.095e-06 50.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - 4.1.1.55 ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000 - - - NMT1 DYD1_k127_1287950_0 521674.Plim_2303 1.602e-16 88.0 COG0553@1|root,COG0553@2|Bacteria,2IXFX@203682|Planctomycetes 203682|Planctomycetes L COG0553 Superfamily II DNA RNA - - - - - - - - - - - - Helicase_C,SNF2_N,SWIM DYD1_k127_1287950_1 1285586.H131_06618 7.689e-11 73.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,3IWDF@400634|Lysinibacillus 91061|Bacilli P NMT1-like family ytlA GO:0003674,GO:0005215 - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_1287950_2 1232410.KI421412_gene421 0.0006339 46.0 2EBKH@1|root,335KX@2|Bacteria,1NAWH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_1294503_2 487521.OCU_39710 5.607e-22 96.0 COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria,237YQ@1762|Mycobacteriaceae 201174|Actinobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_1294503_1 1120949.KB903314_gene302 1.683e-133 446.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria 201174|Actinobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_1294503_0 485913.Krac_1950 8.515e-148 475.0 COG2141@1|root,COG2141@2|Bacteria,2G5JS@200795|Chloroflexi 200795|Chloroflexi C PFAM Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_1294503_3 944435.AXAJ01000001_gene74 1.318e-11 67.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,1K17A@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA,TctB DYD1_k127_1303733_2 1192034.CAP_6251 6.283e-105 351.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_1303733_5 1336208.JADY01000013_gene1576 7.125e-28 117.0 COG0251@1|root,COG0251@2|Bacteria,1RDJX@1224|Proteobacteria,2U7F4@28211|Alphaproteobacteria 28211|Alphaproteobacteria J endoribonuclease L-PSP MA20_04225 - - - - - - - - - - - Ribonuc_L-PSP DYD1_k127_1303733_1 1380394.JADL01000022_gene4 2.452e-110 372.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria,2JW26@204441|Rhodospirillales 204441|Rhodospirillales J Amidase - - - - - - - - - - - - Amidase DYD1_k127_1303733_0 1231391.AMZF01000094_gene122 9.298e-147 485.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_1303733_3 1343740.M271_39840 2.954e-69 246.0 COG0451@1|root,COG0451@2|Bacteria,2GZ4Z@201174|Actinobacteria 201174|Actinobacteria GM PFAM NAD-dependent epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD1_k127_1303733_4 644281.MFS40622_1631 3.085e-53 201.0 COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,23Q9F@183939|Methanococci 183939|Methanococci E D-isomer specific 2-hydroxyacid dehydrogenase catalytic region serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT DYD1_k127_1308691_3 316067.Geob_1586 2.575e-58 207.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,43UPN@69541|Desulfuromonadales 28221|Deltaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) tenI GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI DYD1_k127_1308691_0 330214.NIDE3060 1.816e-121 394.0 COG2022@1|root,COG2022@2|Bacteria,3J0EI@40117|Nitrospirae 40117|Nitrospirae H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG DYD1_k127_1308691_8 1452718.JBOY01000046_gene1044 1.616e-13 72.0 COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,1SGCU@1236|Gammaproteobacteria 1236|Gammaproteobacteria H thiamine biosynthesis protein ThiS thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD1_k127_1308691_5 404589.Anae109_1268 3.833e-53 197.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2Z304@29|Myxococcales 28221|Deltaproteobacteria S Memo-like protein - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo DYD1_k127_1308691_1 401526.TcarDRAFT_2037 5.217e-86 295.0 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4H3E1@909932|Negativicutes 909932|Negativicutes Q FAH family - - - - - - - - - - - - FAA_hydrolase DYD1_k127_1308691_6 439235.Dalk_1767 1.679e-40 166.0 COG1466@1|root,COG1466@2|Bacteria,1RAEB@1224|Proteobacteria,42R0X@68525|delta/epsilon subdivisions,2WMQJ@28221|Deltaproteobacteria,2MJNX@213118|Desulfobacterales 28221|Deltaproteobacteria L DNA polymerase III, delta' holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta DYD1_k127_1308691_7 1158318.ATXC01000001_gene581 1.457e-26 118.0 COG1502@1|root,COG1502@2|Bacteria,2G44G@200783|Aquificae 200783|Aquificae I SMART phospholipase D Transphosphatidylase - - - - - - - - - - - - PLDc_2 DYD1_k127_1308691_2 697281.Mahau_0958 2.53e-60 224.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,42F4N@68295|Thermoanaerobacterales 186801|Clostridia M PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase dacB2 - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 DYD1_k127_1308691_4 420324.KI912060_gene5873 2.768e-54 199.0 COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2TUHQ@28211|Alphaproteobacteria,1JTUY@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM beta-lactamase domain protein MA20_22080 - - - - - - - - - - - Lactamase_B_2 DYD1_k127_1308691_9 1384057.CD33_05275 3.551e-12 76.0 COG1846@1|root,COG1846@2|Bacteria,1VACT@1239|Firmicutes,4HHUZ@91061|Bacilli,3IXS7@400634|Lysinibacillus 91061|Bacilli K MarR family transcriptional regulator ysmB - - - - - - - - - - - MarR DYD1_k127_1347759_3 204669.Acid345_2370 2.908e-36 141.0 COG0304@1|root,COG0304@2|Bacteria,3Y43C@57723|Acidobacteria,2JMFI@204432|Acidobacteriia 204432|Acidobacteriia IQ Beta-ketoacyl synthase, C-terminal domain - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_1347759_0 867903.ThesuDRAFT_01424 4.188e-98 329.0 COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,24GWH@186801|Clostridia 186801|Clostridia S PFAM NAD dependent epimerase dehydratase family - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase DYD1_k127_1347759_1 945713.IALB_2776 1.606e-85 291.0 COG0682@1|root,COG0682@2|Bacteria 2|Bacteria M lipoprotein biosynthetic process lgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 ko:K03438,ko:K13292 - - - - ko00000,ko01000,ko03009 - - - LGT DYD1_k127_1347759_4 671143.DAMO_2648 3.262e-27 119.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K03286,ko:K12976,ko:K16079 - - - - ko00000,ko01000,ko01005,ko02000 1.B.4.2.1,1.B.6 - - CBP_BcsS,DUF3943,OMP_b-brl,PagL DYD1_k127_1347759_5 485913.Krac_1060 6.545e-24 106.0 COG0789@1|root,COG0789@2|Bacteria,2G9AM@200795|Chloroflexi 200795|Chloroflexi K Transcription regulator MerR DNA binding - - - ko:K13638 - - - - ko00000,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 DYD1_k127_1347759_2 869210.Marky_0550 1.834e-69 243.0 COG2217@1|root,COG2217@2|Bacteria,1WJ55@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P ATPase P-type (Transporting), HAD superfamily, subfamily IC - - - - - - - - - - - - E1-E2_ATPase,HMA,Hydrolase DYD1_k127_1357962_0 269799.Gmet_1386 9.952e-190 615.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2WIWF@28221|Deltaproteobacteria,43TQ3@69541|Desulfuromonadales 28221|Deltaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 DYD1_k127_1360035_1 111780.Sta7437_0995 6.704e-07 57.0 COG1493@1|root,COG1493@2|Bacteria,1G59U@1117|Cyanobacteria 1117|Cyanobacteria T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - - - - - - - - - - - DYD1_k127_1360035_0 1183438.GKIL_2156 2.255e-22 111.0 COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria 1117|Cyanobacteria S Uncharacterised nucleotidyltransferase - - - - - - - - - - - - NTP_transf_5 DYD1_k127_1374985_7 1449063.JMLS01000027_gene61 6.659e-17 92.0 COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,26UYR@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_1374985_5 350058.Mvan_1001 9.143e-79 277.0 COG4638@1|root,COG4638@2|Bacteria,2GKMV@201174|Actinobacteria,236I0@1762|Mycobacteriaceae 201174|Actinobacteria P Rieske [2Fe-2S] domain vanA - - ko:K19982 ko00404,ko01130,map00404,map01130 M00790 R11107 RC01333 ko00000,ko00001,ko00002,ko01000 - - - Rieske DYD1_k127_1374985_0 1121033.AUCF01000030_gene174 6.032e-133 437.0 COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2U16N@28211|Alphaproteobacteria,2JVNK@204441|Rhodospirillales 204441|Rhodospirillales E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - - - - - - - - - - Peripla_BP_6 DYD1_k127_1374985_2 1187851.A33M_0278 6.157e-102 340.0 COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2TSH5@28211|Alphaproteobacteria,3FEM5@34008|Rhodovulum 28211|Alphaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_1374985_1 1205680.CAKO01000002_gene3005 6.242e-104 360.0 COG4177@1|root,COG4177@2|Bacteria,1NE3E@1224|Proteobacteria,2TTWY@28211|Alphaproteobacteria,2JT5A@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 DYD1_k127_1374985_4 1244869.H261_06499 1.277e-88 302.0 COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,2JS5W@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_1374985_3 1187851.A33M_0281 5.215e-100 331.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3FD1Y@34008|Rhodovulum 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD1_k127_1374985_8 1117108.PAALTS15_29056 3.858e-16 86.0 COG1335@1|root,COG1335@2|Bacteria,1V371@1239|Firmicutes,4HUPA@91061|Bacilli,26X39@186822|Paenibacillaceae 91061|Bacilli Q Isochorismatase family - - - - - - - - - - - - Isochorismatase DYD1_k127_1374985_6 1095769.CAHF01000021_gene943 1.909e-68 240.0 COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2VVC1@28216|Betaproteobacteria 28216|Betaproteobacteria E Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 DYD1_k127_1425496_0 1254432.SCE1572_43755 5.251e-61 216.0 COG0265@1|root,COG1005@1|root,COG0265@2|Bacteria,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YYND@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh,PDZ_2 DYD1_k127_1425496_1 404589.Anae109_1284 1.765e-49 182.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42SZV@68525|delta/epsilon subdivisions,2WP8T@28221|Deltaproteobacteria,2Z0UI@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338,ko:K05580 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_4,Fer4_7 DYD1_k127_1425496_2 448385.sce8025 3.882e-40 154.0 COG0839@1|root,COG0839@2|Bacteria,1PJW9@1224|Proteobacteria,42V0F@68525|delta/epsilon subdivisions,2WS8G@28221|Deltaproteobacteria,2Z1CQ@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD1_k127_1425496_3 290397.Adeh_2578 6.947e-33 131.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42WIQ@68525|delta/epsilon subdivisions,2WS3A@28221|Deltaproteobacteria,2Z1V8@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD1_k127_1456716_1 251229.Chro_3613 3.282e-100 334.0 COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria 1117|Cyanobacteria U Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP DYD1_k127_1456716_0 215803.DB30_0441 6.911e-129 421.0 COG1063@1|root,COG1063@2|Bacteria,1NXSN@1224|Proteobacteria,438FZ@68525|delta/epsilon subdivisions,2X3QX@28221|Deltaproteobacteria,2YWVR@29|Myxococcales 28221|Deltaproteobacteria E Glucose dehydrogenase C-terminus gcd - - - - - - - - - - - ADH_N,Glu_dehyd_C DYD1_k127_1456716_4 518766.Rmar_2225 3.988e-07 56.0 COG5660@1|root,COG5660@2|Bacteria,4PF9I@976|Bacteroidetes,1FKBP@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Putative zinc-finger - - - - - - - - - - - - zf-HC2 DYD1_k127_1456716_3 1131269.AQVV01000031_gene291 2.369e-07 57.0 2DTSQ@1|root,33MH7@2|Bacteria 2|Bacteria S Putative zinc-finger - - - - - - - - - - - - zf-HC2 DYD1_k127_1456716_2 483219.LILAB_14245 2.009e-29 126.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42URE@68525|delta/epsilon subdivisions,2WR5V@28221|Deltaproteobacteria,2YY8T@29|Myxococcales 28221|Deltaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_1461586_0 485913.Krac_7281 3.253e-78 270.0 COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi 200795|Chloroflexi IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100,1.1.1.140 ko:K00059,ko:K00068 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671 RC00029,RC00085,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_1461586_2 398578.Daci_0104 0.0006436 46.0 2DPNC@1|root,32UMG@2|Bacteria,1N0XW@1224|Proteobacteria,2W38B@28216|Betaproteobacteria,4AI49@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit - - - - - - - - - - - - LigA DYD1_k127_1461586_1 1123023.JIAI01000013_gene4027 3.791e-38 154.0 COG3384@1|root,COG3384@2|Bacteria,2GNCA@201174|Actinobacteria 201174|Actinobacteria S Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively ligB - 1.13.11.57,1.13.11.8 ko:K04099,ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA,LigB DYD1_k127_1462979_13 1120936.KB907221_gene2112 7.21e-17 82.0 COG2159@1|root,COG2159@2|Bacteria,2GN9D@201174|Actinobacteria 201174|Actinobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_1462979_16 635013.TherJR_2572 9.895e-06 55.0 COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,260BF@186807|Peptococcaceae 186801|Clostridia M Cell Wall - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,CW_binding_2,Cu_amine_oxidN1,SH3_3 DYD1_k127_1462979_12 941449.dsx2_1289 4.925e-22 102.0 COG0726@1|root,COG0726@2|Bacteria,1RH3I@1224|Proteobacteria,42T75@68525|delta/epsilon subdivisions,2WPC1@28221|Deltaproteobacteria,2MEZ8@213115|Desulfovibrionales 28221|Deltaproteobacteria G Archaea-specific editing domain of threonyl-tRNA synthetase - - - - - - - - - - - - tRNA-Thr_ED DYD1_k127_1462979_8 289376.THEYE_A0507 8.471e-76 258.0 COG0512@1|root,COG0512@2|Bacteria,3J0H8@40117|Nitrospirae 40117|Nitrospirae EH Peptidase C26 - - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase DYD1_k127_1462979_4 56780.SYN_01947 1.648e-160 520.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,2MQ88@213462|Syntrophobacterales 28221|Deltaproteobacteria H Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657,ko:K13503 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind DYD1_k127_1462979_7 1232410.KI421428_gene1082 8.998e-82 279.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,43THQ@69541|Desulfuromonadales 28221|Deltaproteobacteria K regulatory protein IclR - - - - - - - - - - - - HTH_IclR,IclR DYD1_k127_1462979_0 869210.Marky_0826 0.0 1004.0 COG0247@1|root,COG0247@2|Bacteria,1WIPC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Fe-S oxidoreductase - - - - - - - - - - - - CCG,Fer4_8 DYD1_k127_1462979_11 246197.MXAN_2529 4.15e-32 130.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,42VH9@68525|delta/epsilon subdivisions,2WT3R@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 DYD1_k127_1462979_6 706587.Desti_2694 7.276e-139 450.0 COG0057@1|root,COG0057@2|Bacteria,1N2N1@1224|Proteobacteria 1224|Proteobacteria G Glyceraldehyde-3-phosphate dehydrogenase - - 1.2.1.59 ko:K00150 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166 R01061,R01063 RC00149 ko00000,ko00001,ko00002,ko01000 - - - DapB_N,Gp_dh_C DYD1_k127_1462979_1 671143.DAMO_2859 3.321e-211 665.0 COG0312@1|root,COG0312@2|Bacteria,2NNWH@2323|unclassified Bacteria 2|Bacteria S Putative modulator of DNA gyrase tldD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD DYD1_k127_1462979_3 330214.NIDE1515 1.635e-161 522.0 COG0312@1|root,COG0312@2|Bacteria,3J0P7@40117|Nitrospirae 40117|Nitrospirae S Putative modulator of DNA gyrase - - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD DYD1_k127_1462979_9 1163407.UU7_07173 1.061e-49 186.0 2A5P5@1|root,30UDZ@2|Bacteria,1RHAP@1224|Proteobacteria,1SXHY@1236|Gammaproteobacteria,1X69H@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD1_k127_1462979_2 247490.KSU1_B0659 2.273e-185 590.0 COG0498@1|root,COG0498@2|Bacteria,2IXKE@203682|Planctomycetes 203682|Planctomycetes E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_1462979_5 326427.Cagg_1948 2.46e-139 464.0 COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,376G2@32061|Chloroflexia 32061|Chloroflexia E PFAM Cys Met metabolism pyridoxal-phosphate-dependent - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP DYD1_k127_1462979_10 338963.Pcar_0644 2.808e-39 156.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,43SI8@69541|Desulfuromonadales 28221|Deltaproteobacteria I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_1462979_14 1313172.YM304_37850 4.472e-15 77.0 COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CN61@84992|Acidimicrobiia 84992|Acidimicrobiia H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH DYD1_k127_1466786_13 702450.CUW_0814 2.366e-05 55.0 COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,3VQ7J@526524|Erysipelotrichia 526524|Erysipelotrichia S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 DYD1_k127_1466786_5 404380.Gbem_2452 5.185e-37 141.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,42U6P@68525|delta/epsilon subdivisions,2WQ00@28221|Deltaproteobacteria,43V75@69541|Desulfuromonadales 28221|Deltaproteobacteria L SMART HNH nuclease - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH_5 DYD1_k127_1466786_4 342949.PNA2_1862 1.831e-45 168.0 COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci 183968|Thermococci J Endoribonuclease L-PSP - GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP DYD1_k127_1466786_9 309799.DICTH_1705 5.732e-21 100.0 COG3809@1|root,COG3809@2|Bacteria 2|Bacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - zf-TFIIB DYD1_k127_1466786_0 266117.Rxyl_0345 2.453e-61 223.0 COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria 84995|Rubrobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 DYD1_k127_1466786_1 484019.THA_1091 4.284e-60 213.0 COG1704@1|root,COG1704@2|Bacteria,2GCV5@200918|Thermotogae 200918|Thermotogae S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA DYD1_k127_1466786_3 1382306.JNIM01000001_gene853 2.918e-53 200.0 COG1304@1|root,COG1304@2|Bacteria,2G84G@200795|Chloroflexi 200795|Chloroflexi C FMN-dependent dehydrogenase - - - - - - - - - - - - FMN_dh DYD1_k127_1466786_12 487521.OCU_15350 8.484e-06 57.0 COG0346@1|root,COG0346@2|Bacteria,2GW68@201174|Actinobacteria,23D7F@1762|Mycobacteriaceae 201174|Actinobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase DYD1_k127_1466786_11 1242864.D187_000479 6.18e-08 63.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - ko:K11210 - - - - ko00000,ko01000 - - - Glyoxalase DYD1_k127_1466786_10 436114.SYO3AOP1_1470 7.545e-09 59.0 COG1141@1|root,COG1141@2|Bacteria 2|Bacteria C electron transfer activity - - - ko:K05337 - - - - ko00000 - - - Fer4_13,Fer4_15 DYD1_k127_1466786_2 1042876.PPS_3367 1.058e-54 201.0 COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria 1224|Proteobacteria IQ dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_1466786_7 326427.Cagg_0747 5.369e-30 129.0 COG4221@1|root,COG4221@2|Bacteria,2G6TQ@200795|Chloroflexi,37675@32061|Chloroflexia 32061|Chloroflexia S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD1_k127_1466786_6 1158338.JNLJ01000005_gene1705 1.491e-33 135.0 COG1051@1|root,COG1051@2|Bacteria,2G5I3@200783|Aquificae 200783|Aquificae F NUDIX domain - - - - - - - - - - - - NUDIX DYD1_k127_1466786_8 1267535.KB906767_gene4225 1.1e-27 115.0 COG1324@1|root,COG1324@2|Bacteria,3Y5P7@57723|Acidobacteria 57723|Acidobacteria P CutA1 divalent ion tolerance protein - - - ko:K03926 - - - - ko00000 - - - CutA1 DYD1_k127_1467950_0 1120956.JHZK01000002_gene895 2.284e-10 66.0 2AK96@1|root,31AZF@2|Bacteria,1Q6KQ@1224|Proteobacteria,2VCQI@28211|Alphaproteobacteria,1JQ95@119043|Rhodobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1467950_1 573413.Spirs_1988 1.498e-09 68.0 COG0740@1|root,COG0740@2|Bacteria,2J8UA@203691|Spirochaetes 203691|Spirochaetes OU Belongs to the peptidase S14 family - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease DYD1_k127_1469914_4 713586.KB900536_gene1206 5.3e-64 223.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase - - - - - - - - - - - - MerC,Methyltransf_31 DYD1_k127_1469914_3 502025.Hoch_5247 5.315e-67 233.0 COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM OsmC family protein - - - - - - - - - - - - OsmC DYD1_k127_1469914_2 1459636.NTE_01130 3.663e-72 248.0 COG0456@1|root,arCOG00833@2157|Archaea 2157|Archaea C PFAM GCN5-related N-acetyltransferase - - 2.3.1.1 ko:K00619 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_1469914_1 450851.PHZ_c1673 2.39e-86 296.0 2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1469914_0 290397.Adeh_2253 4.538e-219 697.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales 28221|Deltaproteobacteria K ATPase associated with various cellular activities, AAA_5 - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat DYD1_k127_1469914_5 1122915.AUGY01000020_gene6474 3.043e-60 217.0 COG0235@1|root,COG0235@2|Bacteria 2|Bacteria G Class ii aldolase - - 4.1.1.69,4.1.2.17 ko:K01628,ko:K18256 ko00051,ko00624,ko01120,map00051,map00624,map01120 M00636 R01634,R02262 RC00569,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II,UPF0066 DYD1_k127_1469914_6 710686.Mycsm_02769 1.428e-08 62.0 2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria,23CZ7@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_1474296_3 1229780.BN381_810005 0.0006108 48.0 COG1848@1|root,COG1848@2|Bacteria,2IQB5@201174|Actinobacteria 201174|Actinobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07064 - - - - ko00000 - - - PIN DYD1_k127_1474296_0 318996.AXAZ01000054_gene6389 1.79e-228 714.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 DYD1_k127_1474296_1 1047013.AQSP01000120_gene949 2.332e-06 52.0 COG1943@1|root,COG1943@2|Bacteria 2|Bacteria L Transposase - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp DYD1_k127_1475901_0 1232410.KI421412_gene385 5.465e-56 203.0 COG2755@1|root,COG2755@2|Bacteria,1PS6U@1224|Proteobacteria,43315@68525|delta/epsilon subdivisions,2WXTN@28221|Deltaproteobacteria 28221|Deltaproteobacteria E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 DYD1_k127_1475901_1 330214.NIDE2608 6.976e-06 50.0 COG1943@1|root,COG1943@2|Bacteria 2|Bacteria L Transposase - - - - - - - - - - - - HTH_23,Y1_Tnp DYD1_k127_1485290_0 102232.GLO73106DRAFT_00028020 1.268e-215 675.0 COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria 1117|Cyanobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - iJN678.agp,iSbBS512_1146.agp NTP_transferase DYD1_k127_1485290_2 1193181.BN10_230024 2.282e-43 176.0 COG3573@1|root,COG3573@2|Bacteria,2GIYM@201174|Actinobacteria,4FFER@85021|Intrasporangiaceae 201174|Actinobacteria S Proposed role in polysaccahride synthesis - - - ko:K07077 - - - - ko00000 - - - FAD_binding_2 DYD1_k127_1485290_1 330214.NIDE0557 3.694e-65 230.0 COG0642@1|root,COG0745@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria 2|Bacteria T PhoQ Sensor - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA DYD1_k127_1498480_2 525904.Tter_0410 1.614e-97 331.0 COG2055@1|root,COG2055@2|Bacteria,2NQ9A@2323|unclassified Bacteria 2|Bacteria C Malate/L-lactate dehydrogenase comC - 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 - R02935,R02936 RC00169 ko00000,ko00001,ko01000 - - - Ldh_2 DYD1_k127_1498480_6 1121087.AUCK01000007_gene1675 0.0005953 46.0 COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,4HC5I@91061|Bacilli,1ZD1U@1386|Bacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component ftpA - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_1498480_0 1304875.JAFZ01000001_gene851 2.586e-129 429.0 COG3333@1|root,COG3333@2|Bacteria,3TC23@508458|Synergistetes 508458|Synergistetes S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD1_k127_1498480_4 401526.TcarDRAFT_2562 2.265e-74 261.0 COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,4H4EI@909932|Negativicutes 909932|Negativicutes S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_1498480_1 264732.Moth_2268 2.157e-113 377.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,42FBE@68295|Thermoanaerobacterales 186801|Clostridia C PFAM Alcohol dehydrogenase GroES domain protein - - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_1498480_3 1219031.BBJR01000047_gene1665 1.371e-82 282.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VJKJ@28216|Betaproteobacteria,4ACG8@80864|Comamonadaceae 28216|Betaproteobacteria M PFAM glycosyl transferase family 51 - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase DYD1_k127_1504514_0 1231391.AMZF01000019_gene2027 4.719e-59 213.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria 28216|Betaproteobacteria Q dienelactone hydrolase - - - - - - - - - - - - DLH DYD1_k127_1504514_1 1408444.JHYC01000015_gene2126 3.029e-10 72.0 COG3698@1|root,COG3698@2|Bacteria,1NM1P@1224|Proteobacteria,1SI38@1236|Gammaproteobacteria,1JD4Z@118969|Legionellales 118969|Legionellales S Phosphodiester glycosidase - - - - - - - - - - - - NAGPA DYD1_k127_1506968_2 671143.DAMO_2832 5.308e-141 467.0 COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria 2|Bacteria C NADH dehydrogenase (ubiquinone) activity hycE - - ko:K14089 - - - - ko00000 - - - Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases DYD1_k127_1506968_3 671143.DAMO_2831 2.937e-128 426.0 COG0651@1|root,COG0651@2|Bacteria,2NS4P@2323|unclassified Bacteria 2|Bacteria CP Proton-conducting membrane transporter hyfF GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - ko:K12141 - - - - ko00000,ko01000 - - iECIAI39_1322.ECIAI39_2625,iZ_1308.Z3746 Proton_antipo_M,Proton_antipo_N DYD1_k127_1506968_7 671143.DAMO_2830 3.39e-39 154.0 COG4237@1|root,COG4237@2|Bacteria 2|Bacteria C Hydrogenase 4 membrane hyfE GO:0008150,GO:0040007 - ko:K12140 - - - - ko00000,ko01000 - - - - DYD1_k127_1506968_5 671143.DAMO_2829 2.629e-101 340.0 COG0650@1|root,COG0650@2|Bacteria,2NRV1@2323|unclassified Bacteria 2|Bacteria C NADH dehydrogenase hycD - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_1506968_0 671143.DAMO_2828 3.508e-197 635.0 COG0651@1|root,COG0651@2|Bacteria,2NR9Z@2323|unclassified Bacteria 2|Bacteria CP Proton-conducting membrane transporter hyfB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K12137,ko:K15828 - - - - ko00000,ko01000 - - iB21_1397.B21_02538,iECBD_1354.ECBD_1002,iECB_1328.ECB_02573,iECD_1391.ECD_02573,iECED1_1282.ECED1_3174,iECO111_1330.ECO111_3443,iECO26_1355.ECO26_3788,iECP_1309.ECP_2686,iEKO11_1354.EKO11_1252,iEcHS_1320.EcHS_A2859,iLF82_1304.LF82_1065,iNRG857_1313.NRG857_13330 Proton_antipo_M,Proton_antipo_N DYD1_k127_1506968_6 671143.DAMO_2827 2.939e-59 213.0 COG3260@1|root,COG3260@2|Bacteria,2NRM4@2323|unclassified Bacteria 2|Bacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit hycG - - - - - - - - - - - Oxidored_q6 DYD1_k127_1506968_9 717605.Theco_0007 2.963e-30 123.0 COG0640@1|root,COG0640@2|Bacteria,1V6CU@1239|Firmicutes,4HJ7N@91061|Bacilli,26YN7@186822|Paenibacillaceae 91061|Bacilli K ArsR family transcriptional regulator arsR9 - - - - - - - - - - - HTH_20,HTH_5 DYD1_k127_1506968_1 1033743.CAES01000091_gene2824 1.149e-184 599.0 COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,26TYG@186822|Paenibacillaceae 91061|Bacilli EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A DYD1_k127_1506968_4 1121334.KB911071_gene2052 1.356e-113 387.0 COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,24D6C@186801|Clostridia,3WPJW@541000|Ruminococcaceae 186801|Clostridia EQ Hydantoinase B/oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B DYD1_k127_1506968_8 278957.ABEA03000195_gene469 3.43e-35 136.0 COG5531@1|root,COG5531@2|Bacteria,46T1X@74201|Verrucomicrobia,3K8F3@414999|Opitutae 414999|Opitutae B SWI complex, BAF60b domains - - - - - - - - - - - - SWIB DYD1_k127_1513490_0 1254432.SCE1572_21330 6.394e-207 664.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales 28221|Deltaproteobacteria L ATP dependent DNA ligase domain protein - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M DYD1_k127_1513490_6 748247.AZKH_p0126 1.367e-29 127.0 COG5637@1|root,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,2WGS9@28216|Betaproteobacteria,2KY9H@206389|Rhodocyclales 206389|Rhodocyclales S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - BON DYD1_k127_1513490_7 1128421.JAGA01000001_gene2148 7.883e-27 118.0 2C3FA@1|root,32Y72@2|Bacteria,2NRC8@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1513490_5 926560.KE387023_gene1438 1.51e-55 198.0 COG2323@1|root,COG2323@2|Bacteria,1WK27@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 DYD1_k127_1513490_1 671143.DAMO_3115 9.056e-135 455.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf degP GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 DYD1_k127_1513490_3 234267.Acid_5786 5.447e-127 418.0 COG0265@1|root,COG0265@2|Bacteria,3Y2WB@57723|Acidobacteria 57723|Acidobacteria O PFAM peptidase S1 and S6, chymotrypsin Hap - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_1513490_4 1095769.CAHF01000006_gene1856 1.296e-63 221.0 COG5637@1|root,COG5637@2|Bacteria,1RCEX@1224|Proteobacteria,2VQP4@28216|Betaproteobacteria,4771P@75682|Oxalobacteraceae 28216|Betaproteobacteria O Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc DYD1_k127_1513490_2 485913.Krac_2641 2.442e-127 414.0 COG1233@1|root,COG1233@2|Bacteria,2G60T@200795|Chloroflexi 200795|Chloroflexi Q NAD(P)-binding Rossmann-like domain - - - - - - - - - - - - NAD_binding_8 DYD1_k127_1519431_2 671143.DAMO_1588 1.394e-67 239.0 COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria 2|Bacteria O Cytochrome C assembly protein ccmF GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - ko:K02198,ko:K04016 - - R05712 RC00176 ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD1_k127_1519431_3 671143.DAMO_1587 2.884e-51 188.0 COG0526@1|root,COG0526@2|Bacteria,2NPYK@2323|unclassified Bacteria 2|Bacteria O Thioredoxin-like dsbE - - ko:K02199,ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - AhpC-TSA,Redoxin,Thioredoxin DYD1_k127_1519431_5 671143.DAMO_1586 4.805e-26 124.0 COG3088@1|root,COG3088@2|Bacteria,2NRBD@2323|unclassified Bacteria 2|Bacteria P subunit of a heme lyase ccmH - - ko:K02198,ko:K02200 - - - - ko00000,ko02000 9.B.14.1 - - CcmH DYD1_k127_1519431_7 443152.MDG893_15285 1.313e-09 60.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctA DYD1_k127_1519431_0 1173026.Glo7428_1980 5.875e-156 503.0 COG1253@1|root,COG1253@2|Bacteria,1G16U@1117|Cyanobacteria 1117|Cyanobacteria S PFAM CBS domain - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 DYD1_k127_1519431_1 189753.AXAS01000041_gene2534 2.102e-79 278.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_1519431_8 314278.NB231_01858 1.912e-07 55.0 2DDVB@1|root,2ZJEV@2|Bacteria,1PBKE@1224|Proteobacteria,1SUSK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative addiction module component - - - - - - - - - - - - Unstab_antitox DYD1_k127_1519431_6 1304275.C41B8_10500 6.517e-18 87.0 COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,1T0H5@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin DYD1_k127_1519431_4 1298867.AUES01000085_gene3659 1.605e-41 164.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_1520518_4 706587.Desti_1625 2.454e-22 100.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42UEE@68525|delta/epsilon subdivisions,2WQHS@28221|Deltaproteobacteria,2MS8R@213462|Syntrophobacterales 28221|Deltaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX DYD1_k127_1520518_1 555779.Dthio_PD0754 3.317e-54 195.0 2AFHA@1|root,315HT@2|Bacteria,1N31Y@1224|Proteobacteria,43DNR@68525|delta/epsilon subdivisions,2X6MU@28221|Deltaproteobacteria 28221|Deltaproteobacteria S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_1520518_5 1122915.AUGY01000020_gene6479 6.306e-13 80.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_1520518_0 76114.ebA4709 3.949e-165 546.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,2KUV9@206389|Rhodocyclales 206389|Rhodocyclales S MMPL family - - - ko:K07003 - - - - ko00000 - - - MMPL DYD1_k127_1520518_2 330214.NIDE1725 8.771e-35 146.0 COG4447@1|root,COG4447@2|Bacteria,3J16A@40117|Nitrospirae 40117|Nitrospirae S Photosynthesis system II assembly factor YCF48 - - - - - - - - - - - - PSII_BNR DYD1_k127_1520518_3 1042375.AFPL01000029_gene3376 1.159e-27 126.0 2C4IG@1|root,2Z8A1@2|Bacteria,1QTHZ@1224|Proteobacteria,1SM2W@1236|Gammaproteobacteria,4650V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - DUF1329 DYD1_k127_1530997_17 1122605.KB893628_gene4397 1.489e-05 55.0 COG2940@1|root,COG2940@2|Bacteria,4NQ3D@976|Bacteroidetes 976|Bacteroidetes S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - ko:K07117 - - - - ko00000 - - - SET DYD1_k127_1530997_15 1254432.SCE1572_52330 1.244e-12 76.0 2E3Q4@1|root,32YN3@2|Bacteria,1PXPZ@1224|Proteobacteria,434RA@68525|delta/epsilon subdivisions,2X8ZN@28221|Deltaproteobacteria,2Z16H@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1530997_10 111780.Sta7437_3590 1.745e-34 140.0 COG0797@1|root,COG0797@2|Bacteria,1G0XF@1117|Cyanobacteria,3VKBR@52604|Pleurocapsales 1117|Cyanobacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1 DYD1_k127_1530997_19 1121406.JAEX01000001_gene481 6.976e-05 50.0 COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,42XAV@68525|delta/epsilon subdivisions,2WSJJ@28221|Deltaproteobacteria,2M7R0@213115|Desulfovibrionales 28221|Deltaproteobacteria M TIGRFAM TonB family protein - - - ko:K03646,ko:K03832 - - - - ko00000,ko02000 2.C.1.1,2.C.1.2 - - TonB_2 DYD1_k127_1530997_7 189426.PODO_09040 9.652e-61 220.0 COG0451@1|root,COG0451@2|Bacteria,1TWPP@1239|Firmicutes,4HCTV@91061|Bacilli,26RTK@186822|Paenibacillaceae 91061|Bacilli GM epimerase - - - - - - - - - - - - Epimerase DYD1_k127_1530997_14 926550.CLDAP_38480 7.43e-14 78.0 COG4032@1|root,COG4032@2|Bacteria,2G8KU@200795|Chloroflexi 200795|Chloroflexi S Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 4.1.1.79 ko:K06034 ko00680,ko01120,map00680,map01120 M00358 R05774 RC00506 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_N DYD1_k127_1530997_11 237368.SCABRO_02644 1.253e-19 99.0 COG0028@1|root,COG0028@2|Bacteria,2J4H0@203682|Planctomycetes 203682|Planctomycetes EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_C DYD1_k127_1530997_8 443152.MDG893_15260 1.45e-48 188.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_1530997_4 1123504.JQKD01000012_gene1372 3.578e-76 266.0 COG3384@1|root,COG3384@2|Bacteria,1PVHA@1224|Proteobacteria,2WBB4@28216|Betaproteobacteria,4AHWW@80864|Comamonadaceae 28216|Betaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB DYD1_k127_1530997_5 1297617.JPJD01000050_gene1923 3.035e-68 239.0 COG0684@1|root,COG0684@2|Bacteria,1UYX4@1239|Firmicutes,24DFP@186801|Clostridia,26BA7@186813|unclassified Clostridiales 186801|Clostridia H Aldolase/RraA - - - - - - - - - - - - RraA-like DYD1_k127_1530997_13 1502851.FG93_01800 1.719e-18 98.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2VBE8@28211|Alphaproteobacteria,3JW19@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_6 DYD1_k127_1530997_3 1120972.AUMH01000006_gene1898 7.362e-98 332.0 COG4638@1|root,COG4638@2|Bacteria 2|Bacteria P Rieske (2fe-2S) ligX - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_1530997_6 1120949.KB903314_gene307 2.144e-63 228.0 COG0235@1|root,COG0235@2|Bacteria,2GJ8W@201174|Actinobacteria,4D9VJ@85008|Micromonosporales 201174|Actinobacteria G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II DYD1_k127_1530997_2 1120949.KB903314_gene301 6.273e-98 331.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria 201174|Actinobacteria E Belongs to the ABC transporter superfamily potA - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 DYD1_k127_1530997_1 1120949.KB903314_gene302 3.041e-131 438.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria 201174|Actinobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_1530997_9 1120949.KB903314_gene303 9.312e-48 187.0 COG1840@1|root,COG1840@2|Bacteria 2|Bacteria P iron ion homeostasis - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_1530997_20 1122915.AUGY01000118_gene6536 8.946e-05 54.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_1530997_0 344747.PM8797T_22838 1.567e-214 692.0 COG1067@1|root,COG1067@2|Bacteria,2J2AD@203682|Planctomycetes 203682|Planctomycetes O AAA domain - - - - - - - - - - - - AAA_32,Lon_C DYD1_k127_1530997_12 344747.PM8797T_22843 1.063e-18 91.0 COG0071@1|root,COG0071@2|Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_1530997_21 326427.Cagg_3794 0.0007807 45.0 COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia 32061|Chloroflexia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_1536689_20 713587.THITH_07545 3.494e-50 182.0 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1S6HB@1236|Gammaproteobacteria,1X24R@135613|Chromatiales 135613|Chromatiales S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD1_k127_1536689_2 1476876.JOJO01000036_gene4375 1.373e-219 704.0 COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria 201174|Actinobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_1536689_9 240015.ACP_2222 4.571e-129 425.0 COG0617@1|root,COG0617@2|Bacteria,3Y3B8@57723|Acidobacteria,2JIIS@204432|Acidobacteriia 204432|Acidobacteriia J Probable RNA and SrmB- binding site of polymerase A - - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 DYD1_k127_1536689_26 1191523.MROS_0590 1.666e-24 108.0 COG0745@1|root,COG0745@2|Bacteria 1191523.MROS_0590|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_1536689_11 671143.DAMO_0004 3.787e-114 382.0 COG0612@1|root,COG0612@2|Bacteria,2NPE5@2323|unclassified Bacteria 2|Bacteria S Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_1536689_7 671143.DAMO_0005 2.174e-146 478.0 COG0612@1|root,COG0612@2|Bacteria,2NP50@2323|unclassified Bacteria 2|Bacteria S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_1536689_10 717785.HYPMC_0264 7.384e-117 392.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the UbiD family ubiD - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_1536689_17 1415778.JQMM01000001_gene2213 6.484e-62 220.0 28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,1J4YB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126,SHOCT DYD1_k127_1536689_12 234267.Acid_0345 6.997e-100 333.0 COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria 57723|Acidobacteria S PFAM Chlorite dismutase - - - - - - - - - - - - Chlor_dismutase DYD1_k127_1536689_15 1231391.AMZF01000003_gene3115 2.824e-72 254.0 COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2W95G@28216|Betaproteobacteria,3T7RQ@506|Alcaligenaceae 28216|Betaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 DYD1_k127_1536689_28 754476.Q7A_554 1.214e-18 92.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,45ZTV@72273|Thiotrichales 72273|Thiotrichales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD1_k127_1536689_14 266117.Rxyl_2315 3.911e-78 267.0 2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria 201174|Actinobacteria S PFAM Nitrile hydratase alpha nthA - 4.2.1.84 ko:K01721 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R02828,R04020,R05379,R05596,R07780,R07854 RC00483,RC00792,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_alpha DYD1_k127_1536689_24 266117.Rxyl_2314 8.465e-30 123.0 2DBV6@1|root,32TY6@2|Bacteria 2|Bacteria S Nitrile hydratase beta subunit - - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta DYD1_k127_1536689_29 1121861.KB899922_gene3093 7.216e-18 86.0 2DSG6@1|root,33G0T@2|Bacteria,1QTRS@1224|Proteobacteria,2TVX1@28211|Alphaproteobacteria,2JY7F@204441|Rhodospirillales 204441|Rhodospirillales S Nitrile hydratase beta subunit - - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta DYD1_k127_1536689_0 697281.Mahau_2356 1.227e-268 837.0 COG1274@1|root,COG1274@2|Bacteria,1TQED@1239|Firmicutes,249NP@186801|Clostridia,42FYF@68295|Thermoanaerobacterales 186801|Clostridia H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N DYD1_k127_1536689_16 933262.AXAM01000013_gene1320 1.652e-62 226.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2MJFR@213118|Desulfobacterales 28221|Deltaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C,TruB_C_2,TruB_N DYD1_k127_1536689_25 748658.KB907313_gene2240 5.97e-27 118.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales 135613|Chromatiales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA DYD1_k127_1536689_27 868864.Dester_0239 3.63e-19 90.0 COG1550@1|root,COG1550@2|Bacteria,2G47V@200783|Aquificae 200783|Aquificae S Protein of unknown function (DUF503) - - - ko:K09764 - - - - ko00000 - - - DUF503 DYD1_k127_1536689_1 269799.Gmet_1586 9.104e-261 832.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,43UH5@69541|Desulfuromonadales 28221|Deltaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N DYD1_k127_1536689_30 326427.Cagg_3682 2.105e-14 76.0 COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi,375YN@32061|Chloroflexia 32061|Chloroflexia K Protein of unknown function (DUF448) - - - ko:K07742 - - - - ko00000 - - - DUF448 DYD1_k127_1536689_8 880072.Desac_2286 1.908e-140 459.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MQWA@213462|Syntrophobacterales 28221|Deltaproteobacteria K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 DYD1_k127_1536689_22 667014.Thein_0214 8.553e-35 140.0 COG0779@1|root,COG0779@2|Bacteria,2GH5M@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C DYD1_k127_1536689_13 316067.Geob_1719 5.424e-92 316.0 COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales 28221|Deltaproteobacteria T Nitrogen fixation master sensor histidine kinase, PAS domain-containing gnfL - 2.7.13.3 ko:K02668,ko:K07708,ko:K07709 ko02020,map02020 M00497,M00499,M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8 DYD1_k127_1536689_5 316067.Geob_1720 1.407e-157 510.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales 28221|Deltaproteobacteria T response regulator gnfM - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_1536689_21 324602.Caur_0374 1.15e-46 177.0 COG0352@1|root,COG0352@2|Bacteria,2G6P0@200795|Chloroflexi,375RT@32061|Chloroflexia 32061|Chloroflexia H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI DYD1_k127_1536689_18 706587.Desti_4505 8.101e-58 205.0 COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,42U27@68525|delta/epsilon subdivisions,2WR2V@28221|Deltaproteobacteria 28221|Deltaproteobacteria I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas DYD1_k127_1536689_4 316067.Geob_1746 1.898e-176 563.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,43SXC@69541|Desulfuromonadales 28221|Deltaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C DYD1_k127_1536689_6 1123376.AUIU01000014_gene566 5.787e-157 518.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,3J0Y7@40117|Nitrospirae 40117|Nitrospirae P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C,TrkA_N DYD1_k127_1536689_19 404589.Anae109_0331 1.323e-53 190.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF DYD1_k127_1536689_23 335543.Sfum_3075 9.402e-34 142.0 COG0746@1|root,COG0746@2|Bacteria,1PJ8A@1224|Proteobacteria,43A1A@68525|delta/epsilon subdivisions,2X2C8@28221|Deltaproteobacteria,2MQMN@213462|Syntrophobacterales 28221|Deltaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD1_k127_1536689_3 479434.Sthe_3386 2.457e-189 607.0 COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi,27XT3@189775|Thermomicrobia 189775|Thermomicrobia C Aldehyde ferredoxin oxidoreductase, N-terminal domain - - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N DYD1_k127_154005_4 399549.Msed_0987 0.0007086 50.0 COG5424@1|root,arCOG06031@2157|Archaea 2157|Archaea H pfam tena thi-4 - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4,zf-C2H2_9 DYD1_k127_154005_0 443152.MDG893_15240 1.549e-92 321.0 COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria,1RYIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria E ethanolamine utilization protein eutA GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - ko:K04019 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001 - - - EutA DYD1_k127_154005_2 1380386.JIAW01000030_gene3585 1.599e-25 119.0 COG3435@1|root,COG3435@2|Bacteria,2IE81@201174|Actinobacteria,236XY@1762|Mycobacteriaceae 201174|Actinobacteria Q PFAM Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 DYD1_k127_154005_1 1547437.LL06_00335 1.98e-66 239.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,43IZ4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P 4,5-dihydroxyphthalate decarboxylase - - 4.1.1.55 ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000 - - - NMT1 DYD1_k127_154005_3 502025.Hoch_0434 1.117e-14 76.0 COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria 1224|Proteobacteria E COG0665 Glycine D-amino acid oxidases (deaminating) - - 1.4.99.6 ko:K19746 ko00472,ko01100,map00472,map01100 - R11018 RC00006 ko00000,ko00001,ko01000 - - - DAO DYD1_k127_1561062_6 420324.KI912036_gene2591 6.766e-57 211.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2UQFJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_1561062_9 1216976.AX27061_5649 4.797e-30 126.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T5EX@506|Alcaligenaceae 28216|Betaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_1561062_12 596153.Alide_0137 4.454e-16 83.0 COG3181@1|root,COG3181@2|Bacteria,1NF9R@1224|Proteobacteria,2VM37@28216|Betaproteobacteria,4AC2G@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD1_k127_1561062_7 1177594.MIC448_1190029 3.61e-35 143.0 COG0028@1|root,COG0028@2|Bacteria 2|Bacteria EH Belongs to the TPP enzyme family - - 4.1.1.79 ko:K13039 ko00680,ko01120,map00680,map01120 M00358 R05774 RC00506 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C DYD1_k127_1561062_11 339860.Msp_0278 1.859e-27 117.0 COG4032@1|root,arCOG01613@2157|Archaea,2XYBY@28890|Euryarchaeota,23PJE@183925|Methanobacteria 183925|Methanobacteria S sulfopyruvate decarboxylase, alpha subunit comD - 4.1.1.79 ko:K06034 ko00680,ko01120,map00680,map01120 M00358 R05774 RC00506 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_N DYD1_k127_1561062_14 489825.LYNGBM3L_60180 1.108e-07 61.0 COG0457@1|root,COG0457@2|Bacteria,1G524@1117|Cyanobacteria,1HAVS@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeats - - - - - - - - - - - - TPR_11,TPR_16,TPR_2,TPR_8 DYD1_k127_1561062_3 118166.JH976537_gene3679 6.487e-86 289.0 COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,1HA80@1150|Oscillatoriales 1117|Cyanobacteria Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_1561062_2 479434.Sthe_2813 6.601e-87 296.0 COG1319@1|root,COG1319@2|Bacteria,2G7KW@200795|Chloroflexi,27Z00@189775|Thermomicrobia 189775|Thermomicrobia C CO dehydrogenase flavoprotein domain protein - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_1561062_4 926569.ANT_05700 2.353e-59 212.0 COG2080@1|root,COG2080@2|Bacteria,2G8E9@200795|Chloroflexi 200795|Chloroflexi C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_1561062_0 316058.RPB_3111 8.689e-205 662.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2U2QW@28211|Alphaproteobacteria,3JUUP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_1561062_1 1157708.KB907450_gene6489 1.008e-87 296.0 COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2WEDA@28216|Betaproteobacteria,4ADUF@80864|Comamonadaceae 28216|Betaproteobacteria P PFAM ABC transporter related - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_1561062_8 926550.CLDAP_18390 1.461e-34 146.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process MA20_14880 - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_1561062_5 1218173.BALCAV_0219060 1.944e-57 209.0 COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,4HDSC@91061|Bacilli,1ZAW3@1386|Bacillus 91061|Bacilli P binding-protein-dependent transport systems inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_1561062_13 1041139.KB902646_gene3338 1.771e-08 66.0 COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,4BBDJ@82115|Rhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_1561062_10 1335760.ASTG01000007_gene864 2.331e-28 118.0 COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,2UBU4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Transglycosylase-associated protein MA20_40075 - - - - - - - - - - - Transgly_assoc DYD1_k127_1564814_3 330214.NIDE2608 1.976e-05 48.0 COG1943@1|root,COG1943@2|Bacteria 2|Bacteria L Transposase - - - - - - - - - - - - HTH_23,Y1_Tnp DYD1_k127_1564814_2 604354.TSIB_0634 1.996e-78 274.0 COG2423@1|root,arCOG01035@2157|Archaea,2XTTC@28890|Euryarchaeota 28890|Euryarchaeota E Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate ala GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 ko:K19244 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_1564814_1 1123060.JONP01000027_gene3502 6.8e-79 274.0 COG0596@1|root,COG0596@2|Bacteria,1N54X@1224|Proteobacteria,2U1C2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_1564814_0 945713.IALB_2363 7.477e-88 297.0 COG0656@1|root,COG0656@2|Bacteria 2|Bacteria S aldo-keto reductase (NADP) activity - - - - - - - - - - - - Aldo_ket_red DYD1_k127_159926_0 189753.AXAS01000041_gene2534 2.449e-58 212.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_159926_2 545695.TREAZ_1586 2.712e-27 119.0 COG0526@1|root,COG0526@2|Bacteria,2J8ET@203691|Spirochaetes 203691|Spirochaetes CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA DYD1_k127_159926_5 1304872.JAGC01000009_gene395 4.895e-07 55.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WPH4@28221|Deltaproteobacteria,2MGA9@213115|Desulfovibrionales 28221|Deltaproteobacteria O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD1_k127_159926_4 326427.Cagg_2053 1.543e-09 61.0 COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi,37744@32061|Chloroflexia 32061|Chloroflexia O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD1_k127_159926_1 189753.AXAS01000002_gene5399 1.155e-39 161.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JYHD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_159926_3 1502851.FG93_01336 3.389e-23 106.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_1610352_2 1499967.BAYZ01000005_gene5434 3.565e-05 55.0 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity - - - ko:K08307,ko:K19140 - - - - ko00000,ko01000,ko01011,ko02048 - - - DDE_Tnp_1,DUF772 DYD1_k127_1610352_0 1173028.ANKO01000030_gene3320 1.926e-169 559.0 COG0553@1|root,COG0553@2|Bacteria,1G0JK@1117|Cyanobacteria,1H7QU@1150|Oscillatoriales 1117|Cyanobacteria L PFAM Helicase conserved C-terminal domain - - - - - - - - - - - - DUF3883,Helicase_C,SNF2_N DYD1_k127_1610352_1 240292.Ava_3256 1.28e-30 132.0 2E6E7@1|root,3311P@2|Bacteria,1GDDS@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_1648194_10 595460.RRSWK_05700 4.74e-14 75.0 COG0500@1|root,COG2226@2|Bacteria,2J0WX@203682|Planctomycetes 203682|Planctomycetes Q Methyltransferase domain - - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 DYD1_k127_1648194_11 1232410.KI421420_gene3150 1.006e-13 72.0 COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,43VW0@69541|Desulfuromonadales 28221|Deltaproteobacteria U mttA/Hcf106 family - - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD1_k127_1648194_0 671143.DAMO_3115 1.485e-125 417.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf degP GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 DYD1_k127_1648194_2 1125863.JAFN01000001_gene205 2.334e-97 334.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD1_k127_1648194_6 671143.DAMO_1860 5.698e-48 175.0 COG1487@1|root,COG1487@2|Bacteria 2|Bacteria S nuclease activity - - - - - - - - - - - - PIN DYD1_k127_1648194_9 671143.DAMO_1859 1.125e-19 91.0 COG5450@1|root,COG5450@2|Bacteria 2|Bacteria K positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - - - - - - - - - - VapB_antitoxin DYD1_k127_1648194_7 1123371.ATXH01000002_gene338 6.718e-29 128.0 COG0392@1|root,COG0392@2|Bacteria,2GHR6@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_1648194_4 338963.Pcar_1292 5.358e-78 266.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,43SE3@69541|Desulfuromonadales 28221|Deltaproteobacteria F Formyl transferase purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N DYD1_k127_1648194_1 760568.Desku_1698 2.45e-121 399.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25ZYS@186807|Peptococcaceae 186801|Clostridia F PFAM AIR synthase related protein purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD1_k127_1648194_3 1211115.ALIQ01000201_gene558 1.248e-85 291.0 COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system ATPase component MA20_16895 - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_1648194_8 543728.Vapar_0622 1.693e-27 125.0 COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2VIMG@28216|Betaproteobacteria 28216|Betaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_1648194_5 1416752.AYME01000017_gene1951 4.727e-58 209.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4FPFE@85023|Microbacteriaceae 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_1685476_16 1382306.JNIM01000001_gene2429 1.472e-13 72.0 COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi 200795|Chloroflexi C PFAM dehydrogenase E1 component - - - ko:K21416 - - - - ko00000,ko01000 - - - E1_dh DYD1_k127_1685476_3 485913.Krac_9361 2.848e-117 383.0 COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi 200795|Chloroflexi C PFAM 6-phosphogluconate dehydrogenase NAD-binding - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_1685476_17 1195236.CTER_1678 1.811e-13 75.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 DYD1_k127_1685476_8 138119.DSY0981 3.313e-80 279.0 COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes 1239|Firmicutes E oxidoreductase idhA - 1.1.1.18,1.1.1.369,1.1.1.370 ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951,R09953 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_1685476_7 138119.DSY0967 1.796e-83 285.0 COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24R48@186801|Clostridia,2637S@186807|Peptococcaceae 186801|Clostridia S PFAM Creatininase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase DYD1_k127_1685476_15 1380346.JNIH01000038_gene3856 1.809e-14 76.0 COG1146@1|root,COG1146@2|Bacteria,2IR5A@201174|Actinobacteria 201174|Actinobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_7 DYD1_k127_1685476_5 138119.DSY0972 2.045e-108 373.0 COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,261C3@186807|Peptococcaceae 186801|Clostridia C Succinate dehydrogenase fumarate reductase flavoprotein - - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_1685476_4 246969.TAM4_600 3.236e-111 370.0 COG3839@1|root,arCOG00177@2157|Archaea,2XTU1@28890|Euryarchaeota 28890|Euryarchaeota E COG3842 ABC-type spermidine putrescine transport systems, ATPase components - - 3.6.3.29,3.6.3.30,3.6.3.55 ko:K02010,ko:K02017,ko:K15497 ko02010,map02010 M00189,M00190,M00423 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.5,3.A.1.8 - - ABC_tran,TOBE,TOBE_2 DYD1_k127_1685476_6 1089551.KE386572_gene2549 1.39e-83 298.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_1685476_12 1380394.JADL01000001_gene1960 4.369e-38 156.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2TRY8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system, periplasmic component - - - - - - - - - - - - SBP_bac_6 DYD1_k127_1685476_14 1304865.JAGF01000001_gene1777 4.062e-17 83.0 COG1052@1|root,COG1052@2|Bacteria,2HFW6@201174|Actinobacteria,4F2JI@85016|Cellulomonadaceae 201174|Actinobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_1685476_0 1128421.JAGA01000003_gene2811 3.427e-145 471.0 COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria 2|Bacteria E Threonine synthase MA20_41710 - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_1685476_2 756272.Plabr_3280 2.509e-129 448.0 COG0642@1|root,COG0784@1|root,COG1653@1|root,COG2202@1|root,COG2203@1|root,COG3852@1|root,COG0784@2|Bacteria,COG1653@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3852@2|Bacteria,2IX8Z@203682|Planctomycetes 203682|Planctomycetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,Response_reg DYD1_k127_1685476_1 395964.KE386496_gene361 1.125e-135 449.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,3NCIH@45404|Beijerinckiaceae 28211|Alphaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_1685476_11 1231391.AMZF01000069_gene2124 1.187e-42 162.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT DYD1_k127_1685476_13 640081.Dsui_3156 4.247e-23 108.0 COG0730@1|root,COG0730@2|Bacteria,1RKNK@1224|Proteobacteria,2VY8V@28216|Betaproteobacteria 28216|Betaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE DYD1_k127_1685476_10 42256.RradSPS_2996 3.264e-43 160.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria 84995|Rubrobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_1685476_9 266117.Rxyl_0933 1.066e-76 261.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria 84995|Rubrobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_1755256_1 1123373.ATXI01000024_gene116 2.494e-23 109.0 COG0778@1|root,COG0778@2|Bacteria,2GHHZ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria C Putative TM nitroreductase - - - - - - - - - - - - Nitroreductase DYD1_k127_1755256_0 1028800.RG540_PA09240 8.26e-204 648.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,4B8UI@82115|Rhizobiaceae 28211|Alphaproteobacteria EQ N-methylhydantoinase B acetone carboxylase, alpha subunit - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B DYD1_k127_1755256_2 1408424.JHYI01000008_gene1659 3.049e-05 54.0 COG0860@1|root,COG0860@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,LysM,PG_binding_1,SPOR DYD1_k127_1758716_1 649638.Trad_2275 4.166e-159 518.0 COG0364@1|root,COG0364@2|Bacteria,1WJ2H@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N DYD1_k127_1758716_0 713586.KB900536_gene47 1.034e-267 836.0 COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,1RS4U@1236|Gammaproteobacteria,1X0E1@135613|Chromatiales 135613|Chromatiales G Glycosyl hydrolases family 15 - - - - - - - - - - - - Glyco_hydro_15 DYD1_k127_1758716_3 1095769.CAHF01000005_gene1477 8.222e-146 470.0 COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2VI3B@28216|Betaproteobacteria,475FS@75682|Oxalobacteraceae 28216|Betaproteobacteria L Eukaryotic DNA topoisomerase I, catalytic core - - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_I DYD1_k127_1758716_4 309801.trd_A0069 6.154e-77 271.0 COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia 189775|Thermomicrobia C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_1758716_2 1089553.Tph_c20110 1.07e-148 490.0 COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,42FT8@68295|Thermoanaerobacterales 186801|Clostridia L Transposase IS116 IS110 IS902 family protein - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 DYD1_k127_1758716_9 706587.Desti_0681 1.632e-54 205.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MR87@213462|Syntrophobacterales 2|Bacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_1758716_15 1340434.AXVA01000013_gene356 5.138e-05 55.0 COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,4HHFE@91061|Bacilli,1ZHPX@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_1758716_16 272134.KB731324_gene4835 9.039e-05 52.0 COG0346@1|root,COG0346@2|Bacteria,1G5WY@1117|Cyanobacteria,1HBDT@1150|Oscillatoriales 1117|Cyanobacteria E Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K08234 - - - - ko00000 - - - Glyoxalase DYD1_k127_1758716_6 65393.PCC7424_5738 2.985e-64 235.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,3KGJS@43988|Cyanothece 1117|Cyanobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_1758716_11 1356854.N007_12890 3.425e-32 140.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HD58@91061|Bacilli 91061|Bacilli E Ornithine cyclodeaminase - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_1758716_17 1194972.MVAC_28371 0.0001781 50.0 COG3832@1|root,COG3832@2|Bacteria,2INRZ@201174|Actinobacteria,238K2@1762|Mycobacteriaceae 201174|Actinobacteria S Activator of Hsp90 ATPase 1 family protein - - - - - - - - - - - - Polyketide_cyc2 DYD1_k127_1758716_13 1038859.AXAU01000012_gene4237 6.229e-20 101.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,3JW2Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_1758716_14 1120792.JAFV01000001_gene939 7.48e-06 52.0 COG3668@1|root,COG3668@2|Bacteria 2|Bacteria D Plasmid stabilization system - - - ko:K19092 - - - - ko00000,ko02048 - - - ParE_toxin DYD1_k127_1758716_10 479434.Sthe_2886 1.559e-40 171.0 COG4177@1|root,COG4177@2|Bacteria,2G8KF@200795|Chloroflexi,27YZG@189775|Thermomicrobia 189775|Thermomicrobia E Branched-chain amino acid transport system / permease component - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_1758716_8 243231.GSU2006 1.19e-55 212.0 COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_1758716_5 634956.Geoth_0587 1.056e-75 260.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1WE2D@129337|Geobacillus 91061|Bacilli E ATPases associated with a variety of cellular activities livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD1_k127_1758716_7 1410620.SHLA_35c000280 1.319e-62 222.0 COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,4BBT7@82115|Rhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_1773040_2 1230460.C495_00085 4.809e-119 394.0 COG1804@1|root,arCOG02304@2157|Archaea,2XTW7@28890|Euryarchaeota,23SQV@183963|Halobacteria 183963|Halobacteria C Bile acid-inducible L-carnitine dehydratase protein F - - - - - - - - - - - - CoA_transf_3 DYD1_k127_1773040_12 1132855.KB913035_gene1502 4.122e-43 165.0 COG1611@1|root,COG3350@1|root,COG1611@2|Bacteria,COG3350@2|Bacteria,1R8EU@1224|Proteobacteria 1224|Proteobacteria S YHS domain - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - YHS DYD1_k127_1773040_17 211165.AJLN01000045_gene259 1.142e-12 75.0 COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria,1JIKJ@1189|Stigonemataceae 1117|Cyanobacteria S Putative phosphatase (DUF442) - - - - - - - - - - - - DUF442 DYD1_k127_1773040_15 1336208.JADY01000020_gene3413 4.043e-26 120.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Amidohydrolase - - 4.2.1.83 ko:K10220 ko00362,ko01120,map00362,map01120 - R04478 RC00498 ko00000,ko00001,ko01000 - - - Amidohydro_2 DYD1_k127_1773040_14 909663.KI867150_gene1328 9.136e-35 140.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD1_k127_1773040_11 526227.Mesil_0983 5.503e-45 169.0 COG3265@1|root,COG3265@2|Bacteria,1WMRS@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Shikimate kinase - - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - SKI DYD1_k127_1773040_10 32057.KB217478_gene6789 6.277e-46 172.0 COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria,1HMWG@1161|Nostocales 1117|Cyanobacteria J Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD1_k127_1773040_8 1160137.KB907308_gene6991 2.897e-65 233.0 COG2084@1|root,COG2084@2|Bacteria,2GTGE@201174|Actinobacteria,4G4IQ@85025|Nocardiaceae 201174|Actinobacteria I Domain of unknown function (DUF1932) - - - - - - - - - - - - DUF1932,F420_oxidored,NAD_binding_2 DYD1_k127_1773040_9 42256.RradSPS_1108 1.85e-58 216.0 COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4CPJK@84995|Rubrobacteria 84995|Rubrobacteria V ABC-2 type transporter - - - ko:K09694 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC2_membrane DYD1_k127_1773040_7 408672.NBCG_01492 5.088e-76 266.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DPYJ@85009|Propionibacteriales 201174|Actinobacteria V AAA domain, putative AbiEii toxin, Type IV TA system nodI - - ko:K09695 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC_tran DYD1_k127_1773040_13 391038.Bphy_4029 5.166e-42 170.0 COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2VH1R@28216|Betaproteobacteria,1K2BQ@119060|Burkholderiaceae 28216|Betaproteobacteria M mandelate racemase muconate lactonizing catB - 4.2.1.113,5.5.1.1 ko:K01856,ko:K02549 ko00130,ko00361,ko00362,ko00364,ko00623,ko01100,ko01110,ko01120,ko01220,map00130,map00361,map00362,map00364,map00623,map01100,map01110,map01120,map01220 M00116,M00568 R04031,R05300,R05390,R06989,R08116,R09229 RC00903,RC01038,RC01053,RC01108,RC01321,RC01356 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N DYD1_k127_1773040_5 1380394.JADL01000001_gene2477 2.147e-103 354.0 COG2079@1|root,COG2079@2|Bacteria,1R9ER@1224|Proteobacteria,2U4QI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD1_k127_1773040_4 1125973.JNLC01000018_gene2319 1.753e-103 346.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2U8QU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_1773040_0 1125973.JNLC01000018_gene2320 5.24e-203 643.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD1_k127_1773040_18 408672.NBCG_00489 1.061e-05 54.0 2CQ1K@1|root,32SKA@2|Bacteria,2GSFN@201174|Actinobacteria 201174|Actinobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD1_k127_1773040_1 204669.Acid345_4432 1.838e-162 544.0 COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,3Y61X@57723|Acidobacteria 57723|Acidobacteria T HD domain - - - - - - - - - - - - GAF,HD_5 DYD1_k127_1773040_3 247490.KSU1_D0470 3.535e-112 377.0 COG2211@1|root,COG2211@2|Bacteria,2IY9C@203682|Planctomycetes 203682|Planctomycetes G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_1773040_6 1142394.PSMK_08370 1.011e-82 286.0 COG1077@1|root,COG1077@2|Bacteria 2|Bacteria D Cell shape determining protein MreB Mrl mreB2 - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD1_k127_1773040_16 9601.ENSPPYP00000012231 2.034e-18 102.0 28KVH@1|root,2QTBY@2759|Eukaryota,39SN3@33154|Opisthokonta,3BDC9@33208|Metazoa,3CYDR@33213|Bilateria,48A6G@7711|Chordata,490QE@7742|Vertebrata,3JD04@40674|Mammalia,35IPT@314146|Euarchontoglires,4M9KS@9443|Primates,4MS2F@9604|Hominidae 33208|Metazoa Z Ciliary rootlet component, centrosome cohesion CEP250 GO:0000086,GO:0000226,GO:0000278,GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005814,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007098,GO:0007346,GO:0008022,GO:0008104,GO:0008150,GO:0009987,GO:0010389,GO:0010457,GO:0010564,GO:0015630,GO:0016043,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022402,GO:0022406,GO:0022607,GO:0030030,GO:0030031,GO:0030997,GO:0031023,GO:0031616,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0033365,GO:0034613,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0046605,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0051179,GO:0051493,GO:0051640,GO:0051641,GO:0051726,GO:0060271,GO:0060341,GO:0065007,GO:0070507,GO:0070727,GO:0070925,GO:0071840,GO:0097711,GO:0120031,GO:0120036,GO:0140056,GO:1901987,GO:1901990,GO:1902749,GO:1903047,GO:1903827,GO:1903829,GO:1904779,GO:1904781,GO:1905515 - ko:K16464 - - - - ko00000,ko03036 - - - Rootletin DYD1_k127_1773040_19 9668.ENSMPUP00000010250 0.0005668 54.0 28KWP@1|root,2QTDA@2759|Eukaryota,38G3J@33154|Opisthokonta,3BFXR@33208|Metazoa,3CZQH@33213|Bilateria,47Z9Z@7711|Chordata,495JI@7742|Vertebrata,3JEIQ@40674|Mammalia,3EI0S@33554|Carnivora 33208|Metazoa S Nuclear mitotic apparatus protein 1 NUMA1 GO:0000132,GO:0000226,GO:0000235,GO:0000278,GO:0000922,GO:0001578,GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005815,GO:0005818,GO:0005819,GO:0005829,GO:0005856,GO:0005874,GO:0005876,GO:0005881,GO:0005886,GO:0005938,GO:0006355,GO:0006357,GO:0006996,GO:0006997,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007088,GO:0007163,GO:0007346,GO:0008017,GO:0008022,GO:0008092,GO:0008150,GO:0008289,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010638,GO:0010646,GO:0010647,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016363,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0019904,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030010,GO:0030425,GO:0030510,GO:0030513,GO:0030856,GO:0030858,GO:0030863,GO:0030953,GO:0030981,GO:0031110,GO:0031112,GO:0031113,GO:0031116,GO:0031122,GO:0031323,GO:0031326,GO:0031334,GO:0031616,GO:0031974,GO:0031981,GO:0032271,GO:0032273,GO:0032386,GO:0032388,GO:0032879,GO:0032880,GO:0032886,GO:0032887,GO:0032888,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0035091,GO:0035371,GO:0036449,GO:0036477,GO:0040001,GO:0042634,GO:0042635,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0044085,GO:0044087,GO:0044089,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045595,GO:0045597,GO:0045604,GO:0045606,GO:0045616,GO:0045618,GO:0045682,GO:0045684,GO:0045787,GO:0045840,GO:0045931,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050793,GO:0050794,GO:0051010,GO:0051011,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051179,GO:0051225,GO:0051233,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051293,GO:0051294,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051726,GO:0051783,GO:0051785,GO:0051797,GO:0051798,GO:0051983,GO:0051984,GO:0055028,GO:0055048,GO:0060236,GO:0060255,GO:0060341,GO:0061673,GO:0062033,GO:0065007,GO:0070013,GO:0070507,GO:0070840,GO:0070925,GO:0071840,GO:0071944,GO:0072686,GO:0080090,GO:0090068,GO:0090092,GO:0090100,GO:0090169,GO:0090224,GO:0090235,GO:0090287,GO:0097427,GO:0097431,GO:0097435,GO:0097447,GO:0097458,GO:0097574,GO:0097575,GO:0097718,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0099738,GO:0110028,GO:0120025,GO:0120038,GO:1902115,GO:1902117,GO:1902363,GO:1902365,GO:1902846,GO:1902850,GO:1902903,GO:1902905,GO:1903047,GO:1903506,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1904776,GO:1904778,GO:1905720,GO:1905818,GO:1905820,GO:1905832,GO:1990023,GO:1990752,GO:2000026,GO:2000112,GO:2001141,GO:2001252 - ko:K16808 - - - - ko00000,ko03036 - - - - DYD1_k127_1775383_2 1496688.ER33_11565 1.194e-38 147.0 COG2337@1|root,COG2337@2|Bacteria,1G6KE@1117|Cyanobacteria,22T6U@167375|Cyanobium 1117|Cyanobacteria L Toxic component of a toxin-antitoxin (TA) module - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD1_k127_1775383_3 880072.Desac_1068 5.162e-23 101.0 COG2336@1|root,COG2336@2|Bacteria,1N7YN@1224|Proteobacteria,42VFV@68525|delta/epsilon subdivisions,2WRSX@28221|Deltaproteobacteria 28221|Deltaproteobacteria T SpoVT / AbrB like domain - - - ko:K07172 - - - - ko00000,ko02048 - - - MazE_antitoxin DYD1_k127_1775383_0 756272.Plabr_1636 2.225e-222 704.0 COG4805@1|root,COG4805@2|Bacteria,2IY48@203682|Planctomycetes 203682|Planctomycetes S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD1_k127_1775383_1 485913.Krac_0970 4.609e-54 198.0 COG1011@1|root,COG1011@2|Bacteria,2G9RU@200795|Chloroflexi 2|Bacteria S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase DYD1_k127_1775383_4 1519464.HY22_09295 3.735e-06 52.0 COG5550@1|root,COG5550@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1777605_4 257310.BB0681 3.343e-26 111.0 COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2W02V@28216|Betaproteobacteria 28216|Betaproteobacteria L LVIVD repeat - - - - - - - - - - - - LVIVD DYD1_k127_1777605_0 1337936.IJ00_02960 2.774e-65 228.0 COG0625@1|root,COG0625@2|Bacteria,1G34I@1117|Cyanobacteria,1HKU4@1161|Nostocales 1117|Cyanobacteria O Belongs to the GST superfamily - - 2.5.1.18 ko:K00799,ko:K11209 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N,GST_N_3 DYD1_k127_1777605_5 1121405.dsmv_3794 4.446e-23 102.0 COG2161@1|root,COG2161@2|Bacteria,1Q1KR@1224|Proteobacteria,42UB2@68525|delta/epsilon subdivisions,2WQM4@28221|Deltaproteobacteria,2MKMX@213118|Desulfobacterales 28221|Deltaproteobacteria D Antitoxin Phd_YefM, type II toxin-antitoxin system - - - - - - - - - - - - PhdYeFM_antitox DYD1_k127_1777605_1 880072.Desac_2741 1.366e-46 186.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1NE6G@1224|Proteobacteria,4321S@68525|delta/epsilon subdivisions,2WWD7@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 DYD1_k127_1777605_8 216432.CA2559_06360 0.0004528 48.0 2FDT9@1|root,345TZ@2|Bacteria,4P5PU@976|Bacteroidetes,1IAD0@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_1777605_7 1121897.AUGO01000001_gene1132 1.487e-10 70.0 2DTU6@1|root,33MNJ@2|Bacteria,4NZB3@976|Bacteroidetes,1I72A@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_1777605_2 671143.DAMO_0150 6.247e-30 119.0 2C1SS@1|root,32YN6@2|Bacteria,2NRN5@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_1777605_3 671143.DAMO_0151 1.092e-26 111.0 2E90H@1|root,3339X@2|Bacteria,2NS0Z@2323|unclassified Bacteria 2|Bacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - DYD1_k127_1777605_6 1267535.KB906767_gene4659 9.61e-14 71.0 COG0266@1|root,COG0266@2|Bacteria,3Y71J@57723|Acidobacteria,2JKGK@204432|Acidobacteriia 204432|Acidobacteriia L Formamidopyrimidine-DNA glycosylase H2TH domain - - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD1_k127_1778576_2 1379698.RBG1_1C00001G1465 6.708e-48 176.0 COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family ltp4 - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C DYD1_k127_1778576_0 1469607.KK073768_gene3306 7.03e-163 527.0 COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria,1HIDR@1161|Nostocales 1117|Cyanobacteria IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD1_k127_1778576_1 243265.plu2234 2.391e-102 346.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,1RP02@1236|Gammaproteobacteria 1236|Gammaproteobacteria E histidine ammonia-lyase - - 4.3.1.24 ko:K10775 ko00360,ko00940,ko01100,ko01110,map00360,map00940,map01100,map01110 M00039,M00137,M00350 R00697 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic DYD1_k127_1795229_10 391038.Bphy_3231 4.873e-09 57.0 COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VZNG@28216|Betaproteobacteria,1K6IW@119060|Burkholderiaceae 28216|Betaproteobacteria L similarity to GP 3192745 - - - - - - - - - - - - DDE_Tnp_1_6,DUF772 DYD1_k127_1795229_0 743299.Acife_3182 0.0 1248.0 COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,1RPEF@1236|Gammaproteobacteria,2NDYP@225057|Acidithiobacillales 225057|Acidithiobacillales L AAA domain - - - - - - - - - - - - AAA_11,AAA_12 DYD1_k127_1795229_4 794903.OPIT5_25030 2.02e-27 118.0 COG3415@1|root,COG3415@2|Bacteria 2|Bacteria L Transposase - - - - - - - - - - - - DDE_3,HTH_23,HTH_29,HTH_33 DYD1_k127_1795229_9 1144275.COCOR_05223 7.64e-10 66.0 COG3335@1|root,COG3335@2|Bacteria,1NNID@1224|Proteobacteria 1224|Proteobacteria L DDE superfamily endonuclease - - - - - - - - - - - - DDE_3 DYD1_k127_1795229_1 743299.Acife_3182 1.168e-256 800.0 COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,1RPEF@1236|Gammaproteobacteria,2NDYP@225057|Acidithiobacillales 225057|Acidithiobacillales L AAA domain - - - - - - - - - - - - AAA_11,AAA_12 DYD1_k127_1795229_5 1163617.SCD_n00728 1.166e-22 102.0 2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1795229_2 1051646.VITU9109_14061 9.379e-77 271.0 COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,1R6VW@1224|Proteobacteria,1SNEA@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Pkd domain containing protein - - - - - - - - - - - - - DYD1_k127_1795229_3 1266925.JHVX01000011_gene1490 1.878e-46 174.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,3736X@32003|Nitrosomonadales 28216|Betaproteobacteria M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD1_k127_1796466_4 1124991.MU9_2785 5.212e-10 70.0 COG4319@1|root,COG4319@2|Bacteria,1RBU6@1224|Proteobacteria,1S33C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ketosteroid isomerase - - - - - - - - - - - - SnoaL_3 DYD1_k127_1796466_2 1122604.JONR01000009_gene2347 3.853e-29 127.0 COG0671@1|root,COG0671@2|Bacteria,1RFUF@1224|Proteobacteria,1S722@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Phosphoesterase, PA-phosphatase related - - - - - - - - - - - - PAP2 DYD1_k127_1796466_3 1469607.KK073768_gene2442 4.812e-25 115.0 COG0110@1|root,COG0110@2|Bacteria,1G216@1117|Cyanobacteria,1HN1V@1161|Nostocales 1117|Cyanobacteria S PFAM Bacterial transferase hexapeptide (three repeats) - - - - - - - - - - - - Hexapep DYD1_k127_1796466_0 497964.CfE428DRAFT_1235 4.285e-102 342.0 COG3239@1|root,COG3239@2|Bacteria 2|Bacteria I unsaturated fatty acid biosynthetic process desA - - - - - - - - - - - FA_desaturase DYD1_k127_1796466_1 497964.CfE428DRAFT_1236 2.621e-44 168.0 2DDJA@1|root,2ZIAT@2|Bacteria 2|Bacteria S P-aminobenzoate N-oxygenase AurF - - - - - - - - - - - - AurF DYD1_k127_1796555_0 269799.Gmet_1591 1.208e-263 827.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,43TFC@69541|Desulfuromonadales 28221|Deltaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 DYD1_k127_1796555_1 880072.Desac_2292 6.376e-33 130.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2MQJR@213462|Syntrophobacterales 28221|Deltaproteobacteria J Ribosomal_S15 rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 DYD1_k127_1796555_2 1499967.BAYZ01000003_gene5836 9.884e-25 112.0 COG0457@1|root,COG3577@1|root,COG0457@2|Bacteria,COG3577@2|Bacteria 2|Bacteria S aspartic-type endopeptidase activity - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - Asp_protease_2,TPR_19,gag-asp_proteas DYD1_k127_1796555_3 215803.DB30_4995 3.255e-13 69.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA1 - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC DYD1_k127_180346_1 1230342.CTM_00915 3.766e-66 241.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,36FMV@31979|Clostridiaceae 186801|Clostridia C PFAM L-carnitine dehydratase bile acid-inducible protein F - - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 DYD1_k127_180346_2 1144310.PMI07_005447 2.627e-53 201.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_180346_0 1540221.JQNI01000002_gene2895 2.709e-88 298.0 COG2129@1|root,COG2129@2|Bacteria 2|Bacteria L metallophosphoesterase - - - ko:K07096 - - - - ko00000 - - - Metallophos,Metallophos_2 DYD1_k127_1814767_2 331869.BAL199_04269 8.053e-49 183.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM amidohydrolase 2 - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_1814767_3 700508.D174_16920 1.799e-48 178.0 COG5517@1|root,COG5517@2|Bacteria,2HRZJ@201174|Actinobacteria,239NY@1762|Mycobacteriaceae 201174|Actinobacteria Q Ring hydroxylating beta subunit - - 1.14.12.25 ko:K16303 ko00622,ko01120,ko01220,map00622,map01120,map01220 M00539 R05247 RC00267 br01602,ko00000,ko00001,ko00002,ko01000 - - - Ring_hydroxyl_B DYD1_k127_1814767_0 485913.Krac_3838 2.554e-151 490.0 COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi 200795|Chloroflexi P PFAM Rieske 2Fe-2S domain protein - - 1.14.12.19,1.14.15.7 ko:K00479,ko:K00499,ko:K05708 ko00260,ko00360,ko01120,ko01220,map00260,map00360,map01120,map01220 M00545 R06782,R06783,R07409 RC00087,RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A DYD1_k127_1814767_1 1122915.AUGY01000118_gene6533 5.415e-98 330.0 COG0715@1|root,COG0715@2|Bacteria,1VRJ0@1239|Firmicutes,4HV8W@91061|Bacilli,26U3V@186822|Paenibacillaceae 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - DYD1_k127_1814767_4 871963.Desdi_1047 1.755e-19 93.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,2627C@186807|Peptococcaceae 186801|Clostridia J PFAM Endoribonuclease L-PSP yjgF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP DYD1_k127_1814805_0 592015.HMPREF1705_01808 0.0 1007.0 COG0610@1|root,COG0610@2|Bacteria,3TAA7@508458|Synergistetes 508458|Synergistetes L Subunit R is required for both nuclease and ATPase activities, but not for modification - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII DYD1_k127_1814805_8 631362.Thi970DRAFT_00658 2.256e-08 58.0 COG1848@1|root,COG1848@2|Bacteria 2|Bacteria G Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN,PIN_3 DYD1_k127_1814805_9 551115.Aazo_5205 6.349e-08 57.0 COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HMSA@1161|Nostocales 1117|Cyanobacteria H Belongs to the P-Pant transferase superfamily hetI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS DYD1_k127_1814805_4 697282.Mettu_0560 5.91e-29 124.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1XFJD@135618|Methylococcales 135618|Methylococcales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - DPBB_1 DYD1_k127_1814805_5 1487921.DP68_17130 2.043e-20 94.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,36EJ3@31979|Clostridiaceae 186801|Clostridia T response regulator, receiver arlR - - - - - - - - - - - Response_reg,Trans_reg_C DYD1_k127_1814805_1 391589.RGAI101_3937 2.12e-239 792.0 COG1352@1|root,COG2201@1|root,COG3852@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG3852@2|Bacteria,1NQTI@1224|Proteobacteria 1224|Proteobacteria NT Chemotaxis - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,HATPase_c,HWE_HK,HisKA,HisKA_3,PAS_10,PAS_4,PAS_9,Response_reg DYD1_k127_1814805_7 1089553.Tph_c29170 3.421e-16 88.0 COG0664@1|root,COG0664@2|Bacteria,1TVBM@1239|Firmicutes,25CKA@186801|Clostridia 186801|Clostridia K PFAM Cyclic nucleotide-binding - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding DYD1_k127_1814805_6 264951.V5FNI1 3.71e-17 83.0 COG1109@1|root,2SJJ8@2759|Eukaryota,3AI4Z@33154|Opisthokonta,3PAVE@4751|Fungi,3R178@4890|Ascomycota,20H7J@147545|Eurotiomycetes,3S779@5042|Eurotiales 4751|Fungi G Belongs to the phosphohexose mutase family - - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_1814805_2 1123242.JH636434_gene4886 3.653e-122 416.0 COG0628@1|root,COG0628@2|Bacteria,2IXF5@203682|Planctomycetes 203682|Planctomycetes S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD1_k127_1814805_3 1173028.ANKO01000077_gene5317 7.582e-88 300.0 COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Ribonuclease BN-like family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB DYD1_k127_1822143_2 561175.KB894105_gene946 5.777e-44 172.0 COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria 201174|Actinobacteria S NMT1-like family - - - - - - - - - - - - NMT1_3 DYD1_k127_1822143_3 1122915.AUGY01000118_gene6533 1.769e-39 159.0 COG0715@1|root,COG0715@2|Bacteria,1VRJ0@1239|Firmicutes,4HV8W@91061|Bacilli,26U3V@186822|Paenibacillaceae 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - DYD1_k127_1822143_0 387631.Asulf_01856 4.352e-103 359.0 COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota 28890|Euryarchaeota C aldehyde ferredoxin oxidoreductase - - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N DYD1_k127_1822143_1 443152.MDG893_15467 2.409e-48 186.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_1827418_2 671143.DAMO_1683 1.945e-108 357.0 COG0004@1|root,COG0004@2|Bacteria,2NQS8@2323|unclassified Bacteria 2|Bacteria P Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - iHN637.CLJU_c42670,iYO844.BSU36510 Ammonium_transp DYD1_k127_1827418_3 240015.ACP_3328 7.011e-101 338.0 COG0761@1|root,COG0761@2|Bacteria,3Y40M@57723|Acidobacteria,2JIXC@204432|Acidobacteriia 204432|Acidobacteriia IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB DYD1_k127_1827418_7 1232410.KI421412_gene406 1.443e-67 243.0 COG1193@1|root,COG1193@2|Bacteria,1QYV7@1224|Proteobacteria 1224|Proteobacteria L Glycosyl transferase family 1 - - - - - - - - - - - - - DYD1_k127_1827418_8 156889.Mmc1_1250 1.221e-09 63.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria 1224|Proteobacteria K Cold shock cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD1_k127_1827418_1 926550.CLDAP_17420 1.549e-234 744.0 COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi 200795|Chloroflexi O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH DYD1_k127_1827418_6 1278073.MYSTI_08117 3.5e-74 259.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2YV3C@29|Myxococcales 28221|Deltaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc DYD1_k127_1827418_5 1125863.JAFN01000001_gene2683 2.066e-89 301.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria 28221|Deltaproteobacteria D PFAM Cobyrinic acid ac-diamide synthase soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD1_k127_1827418_0 316067.Geob_3836 4.183e-242 762.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,43TF6@69541|Desulfuromonadales 28221|Deltaproteobacteria D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc DYD1_k127_1827418_4 1121430.JMLG01000002_gene1318 9.038e-95 321.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,260CJ@186807|Peptococcaceae 186801|Clostridia J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N DYD1_k127_183628_2 1123355.JHYO01000003_gene2767 1.684e-33 142.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - Glyco_hydro_108,Glyco_hydro_46 DYD1_k127_183628_1 205922.Pfl01_3712 3.131e-35 143.0 COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,1T07G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_183628_0 1254432.SCE1572_31550 8.666e-73 258.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 28221|Deltaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_1865117_0 671143.DAMO_2322 2.28e-198 634.0 COG2865@1|root,COG2865@2|Bacteria,2NRI7@2323|unclassified Bacteria 2|Bacteria K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,DUF4365,HATPase_c_4 DYD1_k127_1865117_12 1122222.AXWR01000044_gene2347 1.063e-13 71.0 COG0553@1|root,COG0553@2|Bacteria,1WJKM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L PFAM Helicase conserved C-terminal domain - - - - - - - - - - - - DUF3883,Helicase_C,SNF2_N DYD1_k127_1865117_2 1051632.TPY_2012 4.164e-136 460.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis 186801|Clostridia C Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD1_k127_1865117_13 269798.CHU_0210 9.256e-08 58.0 COG2827@1|root,COG2827@2|Bacteria,4NUW1@976|Bacteroidetes,47SQN@768503|Cytophagia 976|Bacteroidetes L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD1_k127_1865117_11 247490.KSU1_D0734 6.566e-35 138.0 COG1656@1|root,COG1656@2|Bacteria 2|Bacteria F Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C DYD1_k127_1865117_8 96561.Dole_0148 1.541e-72 263.0 COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales 28221|Deltaproteobacteria E PFAM transglutaminase domain protein - - - - - - - - - - - - Transglut_core DYD1_k127_1865117_7 1499967.BAYZ01000152_gene1432 6.297e-86 291.0 COG1131@1|root,COG1131@2|Bacteria,2NPDQ@2323|unclassified Bacteria 2|Bacteria V ATPases associated with a variety of cellular activities natA2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_1865117_5 177437.HRM2_33680 6.227e-115 390.0 28M0D@1|root,2ZAFE@2|Bacteria,1R6YH@1224|Proteobacteria,42NPF@68525|delta/epsilon subdivisions,2WM7K@28221|Deltaproteobacteria,2MIG7@213118|Desulfobacterales 28221|Deltaproteobacteria S Putative ATP-binding cassette - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran_2 DYD1_k127_1865117_10 517418.Ctha_2407 4.226e-36 146.0 COG0400@1|root,COG0400@2|Bacteria,1FE1K@1090|Chlorobi 1090|Chlorobi S PFAM phospholipase Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 DYD1_k127_1865117_6 338966.Ppro_3243 3.024e-114 375.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,43T22@69541|Desulfuromonadales 28221|Deltaproteobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 DYD1_k127_1865117_4 525904.Tter_0396 6.831e-124 402.0 COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria 2|Bacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_1865117_9 1379270.AUXF01000004_gene3140 1.757e-58 220.0 COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Putative aminopeptidase - - - - - - - - - - - - Aminopep DYD1_k127_1865117_1 945713.IALB_2638 3e-175 567.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_1865117_3 518766.Rmar_0416 5.023e-134 447.0 COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1FIKV@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes V ABC transporter transmembrane region mdlA - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran DYD1_k127_1865117_14 554065.XP_005844424.1 1.416e-06 52.0 COG0481@1|root,KOG0462@2759|Eukaryota,37K2D@33090|Viridiplantae,34JMY@3041|Chlorophyta 3041|Chlorophyta J Elongation factor G C-terminus - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_1900038_4 345341.KUTG_08561 3.804e-14 77.0 COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria,4E4EM@85010|Pseudonocardiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_1900038_0 436229.JOEH01000014_gene6158 8.066e-87 308.0 COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria,2NGW8@228398|Streptacidiphilus 201174|Actinobacteria EH Thiamine pyrophosphate enzyme, central domain - - 4.1.1.7 ko:K01576 ko00627,ko01120,map00627,map01120 - R01764,R02672 RC00595 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_1900038_3 426117.M446_2277 1.06e-14 85.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria,1JSEU@119045|Methylobacteriaceae 28211|Alphaproteobacteria P PFAM Substrate-binding region of ABC-type glycine betaine transport system MA20_34190 - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_1900038_6 398580.Dshi_1369 1.602e-06 58.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG0235, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - - - - - - - - - - Aldolase_II DYD1_k127_1900038_1 797209.ZOD2009_17383 1.762e-46 178.0 arCOG12117@1|root,arCOG12117@2157|Archaea,2XXVR@28890|Euryarchaeota,23WGQ@183963|Halobacteria 183963|Halobacteria S Protein of unknown function (DUF3891) - - - - - - - - - - - - DUF3891 DYD1_k127_1900038_5 1218084.BBJK01000038_gene3587 1.568e-07 54.0 COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2W2VR@28216|Betaproteobacteria,1K5JP@119060|Burkholderiaceae 28216|Betaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_1900038_2 292415.Tbd_0081 3.707e-31 132.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,1KRH0@119069|Hydrogenophilales 119069|Hydrogenophilales I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_1913500_0 113395.AXAI01000002_gene5167 2.961e-75 261.0 COG1116@1|root,COG1116@2|Bacteria,1NRJ1@1224|Proteobacteria,2UP29@28211|Alphaproteobacteria,3K3PW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran DYD1_k127_1913500_1 113395.AXAI01000002_gene5166 1.142e-64 231.0 COG0600@1|root,COG0600@2|Bacteria,1MVD2@1224|Proteobacteria,2TT6U@28211|Alphaproteobacteria,3JVFT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_1913500_2 316058.RPB_3098 1.037e-13 82.0 COG0715@1|root,COG0715@2|Bacteria,1R9FK@1224|Proteobacteria,2U2KX@28211|Alphaproteobacteria,3K0BG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_1950348_1 1123023.JIAI01000003_gene2637 4.822e-51 191.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_1950348_4 1125973.JNLC01000010_gene1866 3.917e-22 109.0 COG0715@1|root,COG0715@2|Bacteria,1R4AB@1224|Proteobacteria,2U2A0@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport systems periplasmic - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_1950348_2 1463921.JODF01000012_gene317 1.385e-45 179.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_1950348_0 446470.Snas_5606 1.215e-86 293.0 COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EZNM@85014|Glycomycetales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - AAA_assoc_C,ABC_tran DYD1_k127_1950348_3 621372.ACIH01000024_gene4257 1.131e-43 166.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HM1D@91061|Bacilli,26TE8@186822|Paenibacillaceae 91061|Bacilli H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate and vanillate yclC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 ko:K01612,ko:K16874 ko00365,ko00627,ko01120,ko01220,map00365,map00627,map01120,map01220 - R01238,R10213 RC00391,RC03086 ko00000,ko00001,ko01000 - - - UbiD DYD1_k127_1954355_11 1210884.HG799462_gene7872 2.461e-54 199.0 COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes 203682|Planctomycetes H PFAM Biotin lipoate A B protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB DYD1_k127_1954355_0 323261.Noc_1254 0.0 1167.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales 135613|Chromatiales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD1_k127_1954355_6 472759.Nhal_2901 2.223e-101 345.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales 135613|Chromatiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_1954355_4 105559.Nwat_1144 2.131e-150 489.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim DYD1_k127_1954355_5 1232410.KI421421_gene3630 4.451e-108 363.0 COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,42MBD@68525|delta/epsilon subdivisions,2WJT1@28221|Deltaproteobacteria,43SAH@69541|Desulfuromonadales 28221|Deltaproteobacteria E Peptidase family M28 - - 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD1_k127_1954355_8 880074.BARVI_03745 2.919e-64 238.0 COG0724@1|root,COG2865@1|root,COG0724@2|Bacteria,COG2865@2|Bacteria,4NKG2@976|Bacteroidetes,2G2D2@200643|Bacteroidia 976|Bacteroidetes K Divergent AAA domain protein - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4,HTH_24 DYD1_k127_1954355_9 1121918.ARWE01000001_gene3644 5.948e-63 229.0 COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,42N1Q@68525|delta/epsilon subdivisions,2WJJS@28221|Deltaproteobacteria,43TSG@69541|Desulfuromonadales 28221|Deltaproteobacteria Q Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 DYD1_k127_1954355_17 871968.DESME_04965 3.508e-08 60.0 COG1251@1|root,COG1251@2|Bacteria,1VKDD@1239|Firmicutes,24QQH@186801|Clostridia 186801|Clostridia C 2Fe-2S -binding domain - - - - - - - - - - - - Fer2_BFD DYD1_k127_1954355_16 1323663.AROI01000008_gene2627 2.394e-12 76.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria 1224|Proteobacteria C uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center rubA GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575 - - - - - - - - - - Rubredoxin DYD1_k127_1954355_15 653045.Strvi_4346 3.487e-19 96.0 COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_1954355_18 1231391.AMZF01000008_gene1542 1.062e-06 59.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_1954355_12 1109445.AGSX01000043_gene357 2.094e-42 179.0 COG0745@1|root,COG0784@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1Z4IS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T CHASE3 domain - - - - - - - - - - - - 4HB_MCP_1,CHASE3,GAF_2,HATPase_c,HisKA,Response_reg DYD1_k127_1954355_14 1492922.GY26_01675 1.594e-21 101.0 COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,1J710@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components rfaH GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K05785 - - - - ko00000,ko03000 - - - NusG DYD1_k127_1954355_1 472759.Nhal_0667 0.0 1027.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,1WWXB@135613|Chromatiales 135613|Chromatiales T PFAM PrkA AAA - - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA DYD1_k127_1954355_3 472759.Nhal_0668 6.666e-160 512.0 COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,1RQWC@1236|Gammaproteobacteria,1WWH8@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0229 family - - - ko:K09786 - - - - ko00000 - - - DUF444 DYD1_k127_1954355_2 105559.Nwat_0626 6.649e-196 622.0 COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,1WWU8@135613|Chromatiales 135613|Chromatiales S SpoVR family - - - ko:K06415 - - - - ko00000 - - - SpoVR DYD1_k127_1954355_13 398511.BpOF4_13235 3.572e-35 148.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,1ZANW@1386|Bacillus 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N DYD1_k127_1954355_7 479434.Sthe_2304 4.57e-68 237.0 COG0500@1|root,COG2226@2|Bacteria,2G798@200795|Chloroflexi,27Z7K@189775|Thermomicrobia 189775|Thermomicrobia Q Methyltransferase domain - - - - - - - - - - - - - DYD1_k127_1954355_10 926550.CLDAP_10580 4.637e-56 207.0 COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi 200795|Chloroflexi C Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - - - - - - - - - - Caa3_CtaG DYD1_k127_1975631_0 351607.Acel_1068 0.0 1155.0 COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4ERWG@85013|Frankiales 201174|Actinobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD1_k127_1975631_2 1211115.ALIQ01000078_gene4125 4.667e-27 113.0 28JZQ@1|root,2Z9PN@2|Bacteria,1N2WN@1224|Proteobacteria,2U0QD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_1975631_1 1118054.CAGW01000075_gene3261 1.68e-31 136.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_2005647_2 330214.NIDE2937 4.959e-33 132.0 2DNQI@1|root,32YKA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2005647_1 1122622.ATWJ01000014_gene486 2.012e-43 176.0 COG1222@1|root,COG1222@2|Bacteria,2IA0X@201174|Actinobacteria,4FF4V@85021|Intrasporangiaceae 201174|Actinobacteria O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA DYD1_k127_2005647_0 1080067.BAZH01000014_gene437 1.7e-57 202.0 COG1917@1|root,COG1917@2|Bacteria,1RHHY@1224|Proteobacteria 1224|Proteobacteria S Cupin 2, conserved barrel - - - - - - - - - - - - Cupin_2,Cupin_3 DYD1_k127_2059065_8 272624.lpg0148 1.436e-14 82.0 2EE5X@1|root,3380G@2|Bacteria,1NASH@1224|Proteobacteria,1SRRU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2059065_4 159087.Daro_2502 5.667e-34 142.0 29AU1@1|root,2ZXTE@2|Bacteria,1RFMX@1224|Proteobacteria,2W6I0@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2059065_6 395961.Cyan7425_1203 1.145e-30 123.0 COG1669@1|root,COG1669@2|Bacteria,1G7TF@1117|Cyanobacteria,3KIHZ@43988|Cyanothece 1117|Cyanobacteria L PFAM DNA polymerase beta domain protein region - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 DYD1_k127_2059065_5 138119.DSY2810 2.177e-31 128.0 COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes,24QN5@186801|Clostridia,2635X@186807|Peptococcaceae 186801|Clostridia S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 DYD1_k127_2059065_7 485913.Krac_1319 2.068e-15 82.0 COG3427@1|root,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi 200795|Chloroflexi NU PFAM carbon monoxide dehydrogenase subunit G - - - ko:K09386 - - - - ko00000 - - - COXG DYD1_k127_2059065_0 251229.Chro_3912 6.605e-84 298.0 COG2303@1|root,COG2303@2|Bacteria,1FZYZ@1117|Cyanobacteria,3VJHD@52604|Pleurocapsales 1117|Cyanobacteria E COGs COG2303 Choline dehydrogenase and related flavoprotein - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N DYD1_k127_2059065_2 467661.RKLH11_3177 1.366e-49 182.0 COG4032@1|root,COG4032@2|Bacteria,1RFK9@1224|Proteobacteria,2U75B@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - - - - - - - - - - - DYD1_k127_2059065_1 488538.SAR116_0337 6.39e-52 191.0 COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2U67Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_C DYD1_k127_2059065_9 388401.RB2150_18207 6.173e-13 79.0 COG0697@1|root,COG0697@2|Bacteria,1R6SK@1224|Proteobacteria,2U4IR@28211|Alphaproteobacteria 28211|Alphaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD1_k127_2059065_3 313612.L8106_13405 2.484e-46 174.0 COG1878@1|root,COG1878@2|Bacteria,1G60Q@1117|Cyanobacteria,1HHEV@1150|Oscillatoriales 1117|Cyanobacteria S Putative cyclase - - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase DYD1_k127_2063897_1 1500257.JQNM01000014_gene2939 1.584e-29 125.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,2UI7P@28211|Alphaproteobacteria,4BMG3@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_2063897_0 195250.CM001776_gene2695 5.039e-143 457.0 28NY3@1|root,2ZBVC@2|Bacteria,1G5MR@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_2063897_2 330214.NIDE0472 5.784e-26 113.0 COG0394@1|root,COG0394@2|Bacteria 2|Bacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC - 1.20.4.1,3.1.3.48 ko:K01104,ko:K03741 - - - - ko00000,ko01000 - - - FMN_red,LMWPc DYD1_k127_2072498_0 1120973.AQXL01000125_gene3157 1.751e-101 349.0 COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli,278W5@186823|Alicyclobacillaceae 91061|Bacilli EGP Fungal trichothecene efflux pump (TRI12) - - - - - - - - - - - - MFS_1 DYD1_k127_2072498_1 351607.Acel_1472 1.466e-30 136.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_2072498_2 352165.HMPREF7215_1857 1.416e-06 52.0 COG2358@1|root,COG2358@2|Bacteria 2|Bacteria G TRAP transporter, solute receptor (TAXI family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD1_k127_2085295_2 234267.Acid_4641 8.953e-46 172.0 COG1134@1|root,COG1134@2|Bacteria,3Y756@57723|Acidobacteria 57723|Acidobacteria GM Wzt C-terminal domain - - - ko:K09691 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC_tran,Wzt_C DYD1_k127_2085295_0 234267.Acid_4640 7.562e-120 391.0 COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria 57723|Acidobacteria GM ABC-2 type transporter - - - ko:K09690 ko02010,map02010 M00250 - - ko00000,ko00001,ko00002,ko02000 3.A.1.103 - - ABC2_membrane DYD1_k127_2085295_4 504472.Slin_0721 9.783e-24 113.0 COG1216@1|root,COG1216@2|Bacteria,4NP1S@976|Bacteroidetes,47XNT@768503|Cytophagia 976|Bacteroidetes S Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD1_k127_2085295_1 631362.Thi970DRAFT_01496 1.658e-102 345.0 COG0438@1|root,COG0438@2|Bacteria,1R01U@1224|Proteobacteria,1RREV@1236|Gammaproteobacteria,1WWC3@135613|Chromatiales 135613|Chromatiales M PFAM Glycosyl - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 DYD1_k127_2085295_3 604354.TSIB_0855 1.509e-33 143.0 COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,242SB@183968|Thermococci 183968|Thermococci M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_2092291_1 671143.DAMO_1670 1.023e-84 285.0 COG1290@1|root,COG1290@2|Bacteria 2|Bacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - - - - - - - - - - Cytochrom_B_C DYD1_k127_2092291_0 671143.DAMO_1669 6.446e-223 720.0 COG0845@1|root,COG2010@1|root,COG0845@2|Bacteria,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,FIVAR,HlyD_3,PA14,RNA_pol_Rpb1_5 DYD1_k127_2092291_2 671143.DAMO_1668 6.113e-72 250.0 COG3794@1|root,COG3794@2|Bacteria,2NR3M@2323|unclassified Bacteria 2|Bacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - CarboxypepD_reg,fn3_3 DYD1_k127_2092291_3 228405.HNE_2220 2.097e-27 120.0 COG0235@1|root,COG0235@2|Bacteria,1RB5Z@1224|Proteobacteria,2U0PK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Class II aldolase - - - - - - - - - - - - Aldolase_II DYD1_k127_2092291_4 1123368.AUIS01000001_gene2026 7.7e-16 80.0 2E9MH@1|root,333U5@2|Bacteria,1NDRZ@1224|Proteobacteria,1STW7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2092291_5 156889.Mmc1_0139 2.104e-11 75.0 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,2TVXU@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 fpr - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 DYD1_k127_2092291_6 1121351.AUAP01000008_gene1414 1.349e-05 47.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,2KQ07@206351|Neisseriales 206351|Neisseriales IQ Psort location Cytoplasmic, score 9.26 fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_2099991_6 1123360.thalar_02832 2.848e-07 56.0 28N53@1|root,2ZBAC@2|Bacteria,1R6W1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - PMT_2 DYD1_k127_2099991_0 56110.Oscil6304_1708 2.331e-129 424.0 COG0438@1|root,COG0438@2|Bacteria,1G2DD@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Glycosyl transferases group 1 - - - ko:K16703 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 DYD1_k127_2099991_1 521011.Mpal_0174 5.169e-122 408.0 COG2244@1|root,arCOG02209@2157|Archaea,2XU81@28890|Euryarchaeota 28890|Euryarchaeota S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - ko:K03328,ko:K16695 - - - - ko00000,ko02000 2.A.66.2,2.A.66.2.7 - - Polysacc_synt_3,Polysacc_synt_C DYD1_k127_2099991_3 1300345.LF41_383 5.648e-60 214.0 COG0500@1|root,COG0500@2|Bacteria,1QV5S@1224|Proteobacteria,1SDB5@1236|Gammaproteobacteria,1XDH9@135614|Xanthomonadales 135614|Xanthomonadales Q Methyltransferase domain - - - - - - - - - - - - - DYD1_k127_2099991_5 1123401.JHYQ01000025_gene3358 3.741e-35 143.0 COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,1SGGX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep_2,Mac DYD1_k127_2099991_2 557598.LHK_00843 4.898e-62 233.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,2KTZ4@206351|Neisseriales 206351|Neisseriales E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 DYD1_k127_2099991_4 485915.Dret_0280 6.469e-55 194.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales 28221|Deltaproteobacteria E Belongs to the DegT DnrJ EryC1 family arnB - - - - - - - - - - - DegT_DnrJ_EryC1 DYD1_k127_210376_6 69395.JQLZ01000005_gene3594 1.861e-14 78.0 28KKU@1|root,2ZA5K@2|Bacteria,1PTA5@1224|Proteobacteria 1224|Proteobacteria S Alginate lyase - - - - - - - - - - - - Alginate_lyase DYD1_k127_210376_5 41431.PCC8801_0852 2.187e-15 78.0 COG1724@1|root,COG1724@2|Bacteria,1GAH0@1117|Cyanobacteria 1117|Cyanobacteria N PFAM YcfA-like protein - - - - - - - - - - - - HicA_toxin DYD1_k127_210376_3 323261.Noc_1108 8.733e-27 111.0 COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria 1224|Proteobacteria S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - - DYD1_k127_210376_1 1532557.JL37_19440 5.686e-59 216.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria 28216|Betaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_210376_4 1205680.CAKO01000038_gene1807 2.983e-19 93.0 2EFUW@1|root,339M2@2|Bacteria,1R8JP@1224|Proteobacteria,2U5Q7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family MA20_23140 - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB DYD1_k127_210376_0 883078.HMPREF9695_00951 6.957e-170 544.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family MA20_23145 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD1_k127_2114617_4 3694.POPTR_0005s25620.1 5.564e-06 56.0 COG0457@1|root,KOG1124@2759|Eukaryota,37Q78@33090|Viridiplantae,3GCXS@35493|Streptophyta,4JJCQ@91835|fabids 35493|Streptophyta S TPR repeat-containing protein At1g05150-like - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0005886,GO:0005911,GO:0009506,GO:0012505,GO:0016020,GO:0030054,GO:0031410,GO:0031982,GO:0031984,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0055044,GO:0071944,GO:0097708,GO:0098791 - - - - - - - - - - EF-hand_5,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 DYD1_k127_2114617_3 1137799.GZ78_01135 1.979e-26 111.0 COG3012@1|root,COG3012@2|Bacteria,1N1DD@1224|Proteobacteria,1S8TK@1236|Gammaproteobacteria,1XM2G@135619|Oceanospirillales 135619|Oceanospirillales S SEC-C motif - - - - - - - - - - - - SEC-C DYD1_k127_2114617_0 1040989.AWZU01000117_gene3345 1.627e-84 293.0 COG2267@1|root,COG2267@2|Bacteria,1PE1Z@1224|Proteobacteria,2U8Z2@28211|Alphaproteobacteria,3K63X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_2114617_2 262316.MAP_1627 1.862e-26 122.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2114617_1 443152.MDG893_15085 2.627e-43 169.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_2120963_12 1499967.BAYZ01000095_gene4149 5.867e-37 146.0 COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_2120963_4 706587.Desti_2467 2.755e-103 347.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2MQA6@213462|Syntrophobacterales 28221|Deltaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD1_k127_2120963_18 357808.RoseRS_1647 2.186e-09 63.0 COG0789@1|root,COG0789@2|Bacteria,2G72X@200795|Chloroflexi 200795|Chloroflexi K PFAM regulatory protein, MerR - - - ko:K13640 - - - - ko00000,ko03000 - - - MerR_1 DYD1_k127_2120963_3 589865.DaAHT2_0880 9.87e-129 421.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MN5K@213118|Desulfobacterales 28221|Deltaproteobacteria O PFAM peptidase S1 and S6 chymotrypsin Hap - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD1_k127_2120963_2 1232410.KI421413_gene705 7.456e-133 431.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,43S08@69541|Desulfuromonadales 28221|Deltaproteobacteria T AAA domain phoH2 - - ko:K06217 - - - - ko00000 - - - PhoH DYD1_k127_2120963_10 909663.KI867149_gene3216 2.122e-50 183.0 COG0432@1|root,COG0432@2|Bacteria,1N5SN@1224|Proteobacteria,42SJC@68525|delta/epsilon subdivisions,2WP9F@28221|Deltaproteobacteria,2MRXI@213462|Syntrophobacterales 28221|Deltaproteobacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 DYD1_k127_2120963_0 338963.Pcar_2408 3.992e-293 925.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,43THC@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD1_k127_2120963_17 479434.Sthe_1432 1.083e-14 81.0 COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,27YM4@189775|Thermomicrobia 189775|Thermomicrobia S RecX family recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX DYD1_k127_2120963_1 404589.Anae109_0456 1.663e-162 519.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YTSX@29|Myxococcales 28221|Deltaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD1_k127_2120963_14 1379698.RBG1_1C00001G1887 5.967e-32 132.0 COG1514@1|root,COG1514@2|Bacteria,2NPRT@2323|unclassified Bacteria 2|Bacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase DYD1_k127_2120963_6 671143.DAMO_2618 7.326e-87 304.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2NP0G@2323|unclassified Bacteria 2|Bacteria S Belongs to the CinA family cinA GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth DYD1_k127_2120963_16 933262.AXAM01000028_gene3313 1.784e-22 102.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42U6G@68525|delta/epsilon subdivisions,2WQDR@28221|Deltaproteobacteria,2MKIR@213118|Desulfobacterales 28221|Deltaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iAF987.Gmet_0195 PgpA DYD1_k127_2120963_21 1449069.JMLO01000006_gene1077 0.0005221 45.0 COG3224@1|root,COG3224@2|Bacteria,2GY26@201174|Actinobacteria,4FZDB@85025|Nocardiaceae 201174|Actinobacteria S Antibiotic biosynthesis monooxygenase - - - ko:K09932 - - - - ko00000 - - - ABM DYD1_k127_2120963_9 95619.PM1_0200495 9.487e-68 250.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 DYD1_k127_2120963_7 1408424.JHYI01000023_gene4254 4.033e-75 282.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli,1ZDEG@1386|Bacillus 91061|Bacilli S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 DYD1_k127_2120963_15 326427.Cagg_0204 4.228e-26 124.0 COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia 32061|Chloroflexia S von Willebrand factor, type A - - - - - - - - - - - - BatA,VWA_2 DYD1_k127_2120963_11 1123508.JH636443_gene4582 6.45e-45 174.0 COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes 203682|Planctomycetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 DYD1_k127_2120963_5 671143.DAMO_3113 4.897e-92 311.0 COG0603@1|root,COG0603@2|Bacteria,2NPD6@2323|unclassified Bacteria 2|Bacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - iAF987.Gmet_3075 QueC DYD1_k127_2120963_19 1455608.JDTH01000002_gene839 3.262e-07 52.0 COG0607@1|root,arCOG02021@2157|Archaea,2XW44@28890|Euryarchaeota,23S0R@183963|Halobacteria 183963|Halobacteria P COG0607 Rhodanese-related sulfurtransferase - - - - - - - - - - - - Rhodanese DYD1_k127_2120963_20 266117.Rxyl_2941 1.725e-05 53.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria 84995|Rubrobacteria K Rhodanese Homology Domain - - - - - - - - - - - - HTH_20,Rhodanese DYD1_k127_2120963_8 713587.THITH_08925 4.137e-73 257.0 COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria 2|Bacteria S quinone binding - - 3.5.1.104 ko:K12057,ko:K22278 - - - - ko00000,ko01000,ko02044 3.A.7.11.1 - - Thioredoxin_4,VKOR DYD1_k127_2120963_13 497964.CfE428DRAFT_2238 1.145e-36 147.0 COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia 74201|Verrucomicrobia S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD1_k127_2123662_6 748449.Halha_0439 2.519e-126 411.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WAI0@53433|Halanaerobiales 186801|Clostridia P TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain appF - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_2123662_20 450851.PHZ_c2593 1.508e-56 201.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,2KGAN@204458|Caulobacterales 204458|Caulobacterales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N DYD1_k127_2123662_23 1499967.BAYZ01000095_gene4256 7.966e-29 134.0 COG5426@1|root,COG5426@2|Bacteria 2|Bacteria D von Willebrand factor, type A - - - - - - - - - - - - - DYD1_k127_2123662_7 886293.Sinac_2616 2.672e-118 390.0 COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes 203682|Planctomycetes S ATPase associated with - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD1_k127_2123662_16 448385.sce5904 8.739e-65 235.0 COG1721@1|root,COG1721@2|Bacteria,1NEAC@1224|Proteobacteria,43B78@68525|delta/epsilon subdivisions,2X6KP@28221|Deltaproteobacteria,2YWA8@29|Myxococcales 28221|Deltaproteobacteria S Von Willebrand factor type A - - - - - - - - - - - - DUF58 DYD1_k127_2123662_11 1499967.BAYZ01000095_gene4251 5.874e-87 327.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - - - - - - - - - - BatA,VWA_2 DYD1_k127_2123662_1 1499967.BAYZ01000095_gene4241 2.112e-150 526.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 DYD1_k127_2123662_21 221288.JH992901_gene1253 3.641e-49 179.0 COG3805@1|root,COG3805@2|Bacteria,1G7MF@1117|Cyanobacteria,1JM07@1189|Stigonemataceae 1117|Cyanobacteria Q Dopa 4,5-dioxygenase family - - - ko:K10253 - - - - ko00000,ko01000 - - - DOPA_dioxygen DYD1_k127_2123662_25 472759.Nhal_0470 1.663e-24 106.0 2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,1SD5T@1236|Gammaproteobacteria,1X269@135613|Chromatiales 135613|Chromatiales S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 DYD1_k127_2123662_10 479434.Sthe_1533 1.071e-87 299.0 COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi,27YWI@189775|Thermomicrobia 189775|Thermomicrobia C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD1_k127_2123662_27 1459636.NTE_02734 1.386e-15 84.0 arCOG11830@1|root,arCOG11830@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - DYD1_k127_2123662_8 269799.Gmet_2315 4.959e-93 315.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,43TV2@69541|Desulfuromonadales 28221|Deltaproteobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 DYD1_k127_2123662_3 243231.GSU2225 6.399e-134 441.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,43U5B@69541|Desulfuromonadales 28221|Deltaproteobacteria J GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 DYD1_k127_2123662_9 56780.SYN_02797 4.5e-90 309.0 COG0758@1|root,COG4277@1|root,COG0758@2|Bacteria,COG4277@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2MQD6@213462|Syntrophobacterales 28221|Deltaproteobacteria L TIGRFAM DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A DYD1_k127_2123662_0 502025.Hoch_4636 3.753e-264 835.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales 28221|Deltaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom DYD1_k127_2123662_2 1341151.ASZU01000004_gene13 1.304e-148 482.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,27BG8@186824|Thermoactinomycetaceae 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA DYD1_k127_2123662_19 290397.Adeh_0658 2.568e-61 227.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WQJT@28221|Deltaproteobacteria,2YV3J@29|Myxococcales 28221|Deltaproteobacteria FP Ppx GppA gppA-1 - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA DYD1_k127_2123662_24 1131269.AQVV01000038_gene1564 7.342e-27 112.0 COG0776@1|root,COG0776@2|Bacteria 2|Bacteria L regulation of translation hup - - ko:K03530,ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD1_k127_2123662_4 1307759.JOMJ01000004_gene2863 5.084e-129 419.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2M80I@213115|Desulfovibrionales 28221|Deltaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD1_k127_2123662_22 391625.PPSIR1_04398 1.731e-29 122.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Thioesterase superfamily yciA - - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT DYD1_k127_2123662_26 1396418.BATQ01000019_gene4981 2.067e-23 110.0 COG0457@1|root,COG0457@2|Bacteria,46VTD@74201|Verrucomicrobia 74201|Verrucomicrobia S Tetratricopeptide repeat - - - - - - - - - - - - - DYD1_k127_2123662_17 1123386.AUIW01000004_gene771 2.699e-62 225.0 COG3221@1|root,COG3221@2|Bacteria,1WIG6@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd DYD1_k127_2123662_13 867903.ThesuDRAFT_00781 2.868e-76 264.0 COG3638@1|root,COG3638@2|Bacteria,1UKMI@1239|Firmicutes,25FZB@186801|Clostridia 186801|Clostridia P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - - - - - - - - - - - ABC_tran DYD1_k127_2123662_18 760568.Desku_2263 1.248e-61 224.0 COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,24AGQ@186801|Clostridia,262B2@186807|Peptococcaceae 186801|Clostridia P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 DYD1_k127_2123662_14 671143.DAMO_0325 2.93e-74 261.0 COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria 2|Bacteria G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895 NAD_kinase DYD1_k127_2123662_5 338966.Ppro_1578 1.949e-126 424.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,43TM9@69541|Desulfuromonadales 28221|Deltaproteobacteria L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N DYD1_k127_2123662_12 189753.AXAS01000041_gene2534 2.6e-86 296.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_2123662_15 189753.AXAS01000041_gene2534 8.665e-71 248.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_2126099_12 484770.UFO1_2891 1.627e-23 106.0 COG0457@1|root,COG0457@2|Bacteria,1UKPT@1239|Firmicutes,4H6KP@909932|Negativicutes 909932|Negativicutes M Tetratricopeptide repeat - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_2,TPR_8 DYD1_k127_2126099_9 1499967.BAYZ01000017_gene6259 2.126e-53 196.0 COG1215@1|root,COG1215@2|Bacteria,2NPW4@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_2126099_7 237368.SCABRO_02044 5.985e-59 213.0 COG0428@1|root,COG0428@2|Bacteria,2IZ3C@203682|Planctomycetes 203682|Planctomycetes P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip DYD1_k127_2126099_8 330214.NIDE3388 6.568e-56 205.0 COG1208@1|root,COG1208@2|Bacteria,3J0QW@40117|Nitrospirae 40117|Nitrospirae JM Nucleotidyl transferase - - 2.7.7.13 ko:K00966 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD1_k127_2126099_6 330214.NIDE3389 1.663e-69 249.0 COG3178@1|root,COG3178@2|Bacteria,3J15Y@40117|Nitrospirae 40117|Nitrospirae S Phosphotransferase enzyme family - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH DYD1_k127_2126099_14 290397.Adeh_1557 4.391e-13 72.0 COG0695@1|root,COG0695@2|Bacteria,1P8SJ@1224|Proteobacteria,42XTX@68525|delta/epsilon subdivisions 1224|Proteobacteria O Glutaredoxin - - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin DYD1_k127_2126099_5 56107.Cylst_3868 2.721e-81 279.0 COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,1HJVZ@1161|Nostocales 1117|Cyanobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase DYD1_k127_2126099_11 237368.SCABRO_00813 8.733e-29 119.0 COG1254@1|root,COG1254@2|Bacteria,2J4P5@203682|Planctomycetes 203682|Planctomycetes C Acylphosphatase - - - - - - - - - - - - Acylphosphatase DYD1_k127_2126099_10 330214.NIDE3327 1.045e-29 121.0 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif rbpA - - - - - - - - - - - RRM_1 DYD1_k127_2126099_1 243231.GSU0890 2.547e-230 731.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,43TM8@69541|Desulfuromonadales 28221|Deltaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 DYD1_k127_2126099_4 909663.KI867150_gene2934 1.137e-96 337.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MR1G@213462|Syntrophobacterales 28221|Deltaproteobacteria S Anaphase-promoting complex, cyclosome, subunit 3 - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8 DYD1_k127_2126099_13 290397.Adeh_4035 9.337e-18 94.0 COG2834@1|root,COG2834@2|Bacteria,1NMTC@1224|Proteobacteria,42XC3@68525|delta/epsilon subdivisions,2WT97@28221|Deltaproteobacteria,2YWF6@29|Myxococcales 28221|Deltaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - DUF4292 DYD1_k127_2126099_0 713587.THITH_04495 6.309e-296 930.0 COG0747@1|root,COG3889@1|root,COG0747@2|Bacteria,COG3889@2|Bacteria,1R6EI@1224|Proteobacteria 1224|Proteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_2126099_2 926550.CLDAP_11030 4.889e-143 462.0 COG0601@1|root,COG0601@2|Bacteria 2|Bacteria P nitrogen compound transport appB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD1_k127_2126099_3 1255043.TVNIR_2358 1.79e-136 452.0 COG1173@1|root,COG1173@2|Bacteria,1R4K8@1224|Proteobacteria,1SYV4@1236|Gammaproteobacteria,1X02Z@135613|Chromatiales 135613|Chromatiales EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD1_k127_2130209_0 1304878.AUGD01000001_gene851 1.086e-121 417.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,3JS3N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CoA binding domain MA20_23020 - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD1_k127_2130209_3 1118054.CAGW01000075_gene3261 5.501e-30 132.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_2130209_4 690585.JNNU01000009_gene527 3.226e-25 119.0 COG1840@1|root,COG1840@2|Bacteria,1PGNI@1224|Proteobacteria,2V7J9@28211|Alphaproteobacteria,4B9P8@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11 DYD1_k127_2130209_5 572544.Ilyop_0101 1.696e-21 104.0 COG3473@1|root,COG3473@2|Bacteria 2|Bacteria Q Maleate cis-trans isomerase - - 4.1.1.76,5.2.1.1 ko:K01799,ko:K06033 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD1_k127_2130209_1 1192034.CAP_6251 2.222e-73 259.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2130209_2 315730.BcerKBAB4_2523 2.344e-57 207.0 COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HCPF@91061|Bacilli,1ZQWS@1386|Bacillus 91061|Bacilli K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 DYD1_k127_2132228_3 1380355.JNIJ01000026_gene1327 4.752e-32 130.0 2B41E@1|root,31WRS@2|Bacteria,1P8VA@1224|Proteobacteria,2TT81@28211|Alphaproteobacteria,3JUBQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2132228_8 794903.OPIT5_21140 2.722e-14 80.0 COG1853@1|root,COG1853@2|Bacteria,46YS6@74201|Verrucomicrobia,3K927@414999|Opitutae 414999|Opitutae S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct DYD1_k127_2132228_4 1144310.PMI07_005585 2.695e-31 136.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_2132228_6 402777.KB235903_gene687 5.493e-18 87.0 COG3153@1|root,COG3153@2|Bacteria 2|Bacteria S transferase activity, transferring acyl groups - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_2132228_5 402777.KB235903_gene687 1.256e-22 99.0 COG3153@1|root,COG3153@2|Bacteria 2|Bacteria S transferase activity, transferring acyl groups - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 DYD1_k127_2132228_7 1123060.JONP01000017_gene5364 1.092e-14 77.0 2EIDG@1|root,33C4V@2|Bacteria,1N0P4@1224|Proteobacteria,2UC9K@28211|Alphaproteobacteria,2JY84@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD1_k127_2132228_0 1278073.MYSTI_06591 8.936e-70 243.0 COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,43BAG@68525|delta/epsilon subdivisions,2X6PP@28221|Deltaproteobacteria,2YUZG@29|Myxococcales 28221|Deltaproteobacteria H O-methyltransferase - - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 DYD1_k127_2132228_2 696281.Desru_0472 2.791e-32 136.0 COG2159@1|root,COG2159@2|Bacteria,1V0UC@1239|Firmicutes,24ER8@186801|Clostridia,261BS@186807|Peptococcaceae 186801|Clostridia S PFAM amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2132228_1 324602.Caur_2099 1.709e-33 133.0 COG1669@1|root,COG1669@2|Bacteria,2G76P@200795|Chloroflexi 200795|Chloroflexi L PFAM DNA polymerase, beta domain protein region - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 DYD1_k127_2133149_10 381666.PHG174 1.861e-15 77.0 2E52W@1|root,32ZW3@2|Bacteria,1RIGH@1224|Proteobacteria,2VT9W@28216|Betaproteobacteria,1KDNK@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - UPF0158 DYD1_k127_2133149_12 573370.DMR_04550 6.092e-12 72.0 COG1598@1|root,COG1598@2|Bacteria,1RIRX@1224|Proteobacteria,42W3D@68525|delta/epsilon subdivisions,2WRPE@28221|Deltaproteobacteria,2MC8P@213115|Desulfovibrionales 28221|Deltaproteobacteria S HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox DYD1_k127_2133149_13 272123.Anacy_2755 1.891e-10 61.0 COG1724@1|root,COG1724@2|Bacteria,1GI62@1117|Cyanobacteria,1HT1T@1161|Nostocales 1117|Cyanobacteria N Periplasmic or secreted lipoprotein - - - - - - - - - - - - HicA_toxin DYD1_k127_2133149_0 472759.Nhal_0042 1.534e-252 790.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1WX9W@135613|Chromatiales 135613|Chromatiales P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N DYD1_k127_2133149_8 1100720.ALKN01000052_gene507 8.337e-56 211.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria 1224|Proteobacteria G Major facilitator Superfamily MA20_02120 - - - - - - - - - - - MFS_1 DYD1_k127_2133149_14 1121861.KB899920_gene2811 8.339e-06 52.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,2JQKH@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DUF3394,DctM DYD1_k127_2133149_6 634452.APA01_12740 2.953e-78 271.0 COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,2U3ND@28211|Alphaproteobacteria,2JSNM@204441|Rhodospirillales 204441|Rhodospirillales S Phenazine biosynthesis-like protein - - - - - - - - - - - - PhzC-PhzF DYD1_k127_2133149_2 671143.DAMO_3037 3.082e-247 773.0 COG0129@1|root,COG0129@2|Bacteria,2NNSM@2323|unclassified Bacteria 2|Bacteria EG Belongs to the IlvD Edd family ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD1_k127_2133149_3 331869.BAL199_09725 1.136e-105 354.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,4BPX6@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C L-lactate dehydrogenase - - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh DYD1_k127_2133149_5 489825.LYNGBM3L_47830 4.741e-79 272.0 COG1526@1|root,COG1526@2|Bacteria,1G2ZE@1117|Cyanobacteria,1H96K@1150|Oscillatoriales 1117|Cyanobacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ DYD1_k127_2133149_7 1123278.KB893387_gene4337 8.108e-66 240.0 COG2755@1|root,COG3391@1|root,COG2755@2|Bacteria,COG3391@2|Bacteria,4PI0M@976|Bacteroidetes,47R8B@768503|Cytophagia 976|Bacteroidetes E FG-GAP repeat - - - - - - - - - - - - VCBS DYD1_k127_2133149_11 83406.HDN1F_07940 1.224e-12 72.0 COG2010@1|root,COG2010@2|Bacteria,1N63J@1224|Proteobacteria 1224|Proteobacteria C cytochrome c - - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3 DYD1_k127_2133149_9 1457250.BBMO01000003_gene3030 5.071e-18 95.0 COG3301@1|root,arCOG02027@2157|Archaea,2XYFH@28890|Euryarchaeota,23WFI@183963|Halobacteria 183963|Halobacteria P PFAM Polysulphide reductase, NrfD - - - ko:K04015 - - - - ko00000 - - - NrfD DYD1_k127_2133149_4 1167006.UWK_01281 1.192e-87 294.0 COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,42NCU@68525|delta/epsilon subdivisions,2WSB6@28221|Deltaproteobacteria,2MQ1V@213118|Desulfobacterales 28221|Deltaproteobacteria C 4Fe-4S binding domain - - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Fer4_11 DYD1_k127_2133149_1 717231.Flexsi_1074 5.65e-251 793.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GF4C@200930|Deferribacteres 200930|Deferribacteres C Molybdopterin oxidoreductase Fe4S4 domain - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_2137521_4 243164.DET0034 2.114e-07 52.0 COG0306@1|root,COG0306@2|Bacteria,2G7NA@200795|Chloroflexi,34D49@301297|Dehalococcoidia 301297|Dehalococcoidia P Phosphate transporter family - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 DYD1_k127_2137521_2 580327.Tthe_0052 4.097e-73 253.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,42F7S@68295|Thermoanaerobacterales 186801|Clostridia L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 DYD1_k127_2137521_3 646529.Desaci_0021 1.656e-29 126.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,262CP@186807|Peptococcaceae 186801|Clostridia S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd DYD1_k127_2137521_1 243231.GSU0094 7.524e-133 442.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria 28221|Deltaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 DYD1_k127_2137521_0 1403819.BATR01000195_gene6595 1.413e-141 469.0 COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia 74201|Verrucomicrobia L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1 DYD1_k127_2138628_0 234267.Acid_6640 1.326e-189 604.0 COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,3Y2V9@57723|Acidobacteria 2|Bacteria T Sigma-54 interaction domain - - - ko:K02584,ko:K07713,ko:K15836,ko:K21009 ko02020,ko02025,map02020,map02025 M00499 - - ko00000,ko00001,ko00002,ko02022,ko03000 - - - GAF,GAF_2,HTH_8,PocR,Sigma54_activat,Yop-YscD_cpl DYD1_k127_2138628_1 247490.KSU1_D1049 6.446e-174 562.0 COG1178@1|root,COG1178@2|Bacteria,2J51F@203682|Planctomycetes 203682|Planctomycetes U Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_2138628_3 247490.KSU1_D1048 6.215e-103 346.0 COG3842@1|root,COG3842@2|Bacteria,2IZ1J@203682|Planctomycetes 203682|Planctomycetes P PFAM ABC transporter - - - - - - - - - - - - ABC_tran,TOBE_2 DYD1_k127_2138628_2 247490.KSU1_D1047 1.072e-107 368.0 COG1840@1|root,COG1840@2|Bacteria,2J39X@203682|Planctomycetes 203682|Planctomycetes P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_6 DYD1_k127_2151995_1 1231391.AMZF01000066_gene1898 6.484e-134 432.0 COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2VM1S@28216|Betaproteobacteria,3T51K@506|Alcaligenaceae 28216|Betaproteobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2151995_3 443152.MDG893_15467 2.598e-49 202.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_2151995_0 713587.THITH_03235 2.43e-202 649.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM DYD1_k127_2151995_2 713586.KB900536_gene844 5.762e-121 397.0 COG2358@1|root,COG2358@2|Bacteria,1NRSC@1224|Proteobacteria 1224|Proteobacteria S TRAP transporter, solute receptor (TAXI family - - - - - - - - - - - - NMT1_3 DYD1_k127_2151995_4 697303.Thewi_0630 5.244e-34 141.0 COG2267@1|root,COG2267@2|Bacteria,1TPI0@1239|Firmicutes,247QR@186801|Clostridia,42H1C@68295|Thermoanaerobacterales 186801|Clostridia I Ndr family - - 1.11.1.10,3.1.1.24 ko:K00433,ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_4 DYD1_k127_2166822_5 1146883.BLASA_1767 3.832e-27 119.0 2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria,4EX0H@85013|Frankiales 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_2166822_9 1038860.AXAP01000197_gene2220 0.0006429 45.0 COG0251@1|root,COG0251@2|Bacteria,1RAKQ@1224|Proteobacteria,2U5F4@28211|Alphaproteobacteria,3K1NP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD1_k127_2166822_7 237368.SCABRO_01869 5.493e-20 93.0 COG4118@1|root,COG4118@2|Bacteria 2|Bacteria D positive regulation of growth - - - - - - - - - - - - PhdYeFM_antitox DYD1_k127_2166822_4 96561.Dole_1902 1.305e-34 138.0 COG1848@1|root,COG1848@2|Bacteria,1N5DS@1224|Proteobacteria,43BCN@68525|delta/epsilon subdivisions,2X6RK@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Large family of predicted nucleotide-binding domains - - - - - - - - - - - - PIN DYD1_k127_2166822_3 314270.RB2083_1634 4.026e-35 145.0 COG0715@1|root,COG0715@2|Bacteria,1R8AT@1224|Proteobacteria,2U2Z7@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - DYD1_k127_2166822_2 700508.D174_16920 8.903e-45 168.0 COG5517@1|root,COG5517@2|Bacteria,2HRZJ@201174|Actinobacteria,239NY@1762|Mycobacteriaceae 201174|Actinobacteria Q Ring hydroxylating beta subunit - - 1.14.12.25 ko:K16303 ko00622,ko01120,ko01220,map00622,map01120,map01220 M00539 R05247 RC00267 br01602,ko00000,ko00001,ko00002,ko01000 - - - Ring_hydroxyl_B DYD1_k127_2166822_0 485913.Krac_3838 1.545e-151 490.0 COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi 200795|Chloroflexi P PFAM Rieske 2Fe-2S domain protein - - 1.14.12.19,1.14.15.7 ko:K00479,ko:K00499,ko:K05708 ko00260,ko00360,ko01120,ko01220,map00260,map00360,map01120,map01220 M00545 R06782,R06783,R07409 RC00087,RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A DYD1_k127_2166822_6 1122917.KB899670_gene4308 1.187e-25 117.0 COG2159@1|root,COG2159@2|Bacteria,1V0UC@1239|Firmicutes,4HNEI@91061|Bacilli,2701T@186822|Paenibacillaceae 91061|Bacilli S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2166822_1 316058.RPB_3109 1.086e-71 246.0 COG0662@1|root,COG0662@2|Bacteria,1P536@1224|Proteobacteria,2TXFV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Cupin - - - - - - - - - - - - Cupin_2 DYD1_k127_217759_7 1123072.AUDH01000002_gene2353 1.448e-74 257.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Methionine synthase MA20_07800 - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_217759_8 338963.Pcar_1431 2.315e-61 216.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,43SGN@69541|Desulfuromonadales 28221|Deltaproteobacteria F Phosphoribosyl transferase domain apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran DYD1_k127_217759_10 404589.Anae109_1296 2.941e-48 179.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2WRSP@28221|Deltaproteobacteria,2Z31G@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 DYD1_k127_217759_0 1313301.AUGC01000011_gene1125 1.741e-312 968.0 COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes 976|Bacteroidetes H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM DYD1_k127_217759_5 671143.DAMO_0862 4.894e-117 383.0 COG0152@1|root,COG0152@2|Bacteria,2NP0V@2323|unclassified Bacteria 2|Bacteria F SAICAR synthetase purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 ko:K01923,ko:K01945,ko:K03566 ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026 M00048 R04144,R04591 RC00064,RC00090,RC00162,RC00166 ko00000,ko00001,ko00002,ko01000,ko03000 - - - SAICAR_synt DYD1_k127_217759_11 234267.Acid_2478 3.932e-12 70.0 COG1393@1|root,COG1393@2|Bacteria 2|Bacteria P arsenate reductase (glutaredoxin) activity - - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC DYD1_k127_217759_6 1194972.MVAC_00110 1.342e-99 341.0 COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria,237YQ@1762|Mycobacteriaceae 201174|Actinobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_217759_4 1380390.JIAT01000009_gene1212 5.263e-141 464.0 COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4CPPX@84995|Rubrobacteria 84995|Rubrobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 ko:K00135,ko:K22445 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_217759_9 68570.DC74_4648 6.335e-56 207.0 COG1028@1|root,COG1028@2|Bacteria,2IDY5@201174|Actinobacteria 201174|Actinobacteria IQ Polysaccharide biosynthesis protein - - - - - - - - - - - - adh_short_C2 DYD1_k127_217759_1 330214.NIDE3448 2.308e-187 590.0 COG2805@1|root,COG2805@2|Bacteria,3J0YS@40117|Nitrospirae 40117|Nitrospirae NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD1_k127_217759_2 330214.NIDE3449 1.259e-149 482.0 COG5008@1|root,COG5008@2|Bacteria 2|Bacteria NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD1_k127_217759_3 330214.NIDE3449 1.089e-146 474.0 COG5008@1|root,COG5008@2|Bacteria 2|Bacteria NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD1_k127_2181557_1 1121015.N789_11970 1.032e-203 641.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,1X75V@135614|Xanthomonadales 135614|Xanthomonadales CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 DYD1_k127_2181557_4 469383.Cwoe_4099 3.206e-88 301.0 COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria 201174|Actinobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_2181557_19 2002.JOEQ01000017_gene7799 2.135e-05 54.0 COG1917@1|root,COG1917@2|Bacteria,2I3J0@201174|Actinobacteria 201174|Actinobacteria S Cupin 2, conserved barrel - - - - - - - - - - - - Cupin_2 DYD1_k127_2181557_20 1194972.MVAC_09209 0.000336 52.0 COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_2181557_2 1288494.EBAPG3_4650 1.057e-189 606.0 COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2VKYD@28216|Betaproteobacteria,37424@32003|Nitrosomonadales 28216|Betaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_2181557_18 391937.NA2_02759 3.906e-07 55.0 COG5500@1|root,COG5500@2|Bacteria,1N0PP@1224|Proteobacteria,2U7MA@28211|Alphaproteobacteria,43KJ6@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S integral membrane protein - - - - - - - - - - - - DUF1772 DYD1_k127_2181557_16 246197.MXAN_0548 9.111e-14 71.0 COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,438B8@68525|delta/epsilon subdivisions,2X1TZ@28221|Deltaproteobacteria,2YWF2@29|Myxococcales 28221|Deltaproteobacteria O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N DYD1_k127_2181557_7 1254432.SCE1572_37995 4.383e-65 225.0 COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,439P5@68525|delta/epsilon subdivisions,2X50M@28221|Deltaproteobacteria,2YZXZ@29|Myxococcales 28221|Deltaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII DYD1_k127_2181557_10 1288494.EBAPG3_4640 1.926e-53 190.0 COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,2WA6I@28216|Betaproteobacteria,3749W@32003|Nitrosomonadales 28216|Betaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII DYD1_k127_2181557_9 1411123.JQNH01000001_gene807 5.13e-58 204.0 COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2U5A4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K04750 - - - - ko00000 - - - 3-dmu-9_3-mt DYD1_k127_2181557_6 1266925.JHVX01000007_gene2418 5.235e-76 261.0 COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VRJ0@28216|Betaproteobacteria,374MK@32003|Nitrosomonadales 28216|Betaproteobacteria S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt DYD1_k127_2181557_11 1116472.MGMO_35c00160 2.271e-46 171.0 COG3795@1|root,COG3795@2|Bacteria,1RK95@1224|Proteobacteria,1S6H7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII DYD1_k127_2181557_0 330214.NIDE3482 4.392e-220 686.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - BNR DYD1_k127_2181557_13 2002.JOEQ01000031_gene1648 1.092e-43 161.0 COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4EPKG@85012|Streptosporangiales 201174|Actinobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - - - - - - - - - - ThiS DYD1_k127_2181557_8 1121015.N789_03795 7.991e-62 214.0 COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,1S6KT@1236|Gammaproteobacteria,1X7NJ@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1428) - - - - - - - - - - - - DUF1428 DYD1_k127_2181557_5 686340.Metal_0500 4.656e-82 289.0 COG2853@1|root,COG2853@2|Bacteria,1QV20@1224|Proteobacteria,1T26H@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Lipoprotein - - - - - - - - - - - - - DYD1_k127_2181557_3 146922.JOFU01000020_gene2529 2.368e-93 318.0 COG2355@1|root,COG2355@2|Bacteria 2|Bacteria E Zn-dependent dipeptidase, microsomal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Dickkopf_N,Peptidase_M19,Ricin_B_lectin DYD1_k127_2181557_17 1384056.N787_00675 6.609e-08 57.0 COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,1XCMA@135614|Xanthomonadales 135614|Xanthomonadales O Belongs to the glutathione peroxidase family - - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx DYD1_k127_2181557_12 1532558.JL39_00915 4.939e-46 179.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_2181557_15 1410620.SHLA_86c000170 1.224e-15 77.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2TSWU@28211|Alphaproteobacteria,4B7IV@82115|Rhizobiaceae 28211|Alphaproteobacteria L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD1_k127_218188_6 485918.Cpin_1365 3.86e-21 106.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD1_k127_218188_4 1005999.GLGR_1569 5.572e-74 253.0 COG0671@1|root,COG0671@2|Bacteria,1QFZ7@1224|Proteobacteria,1S190@1236|Gammaproteobacteria 1236|Gammaproteobacteria I PAP2 superfamily - - - - - - - - - - - - PAP2_3 DYD1_k127_218188_2 1121918.ARWE01000001_gene1548 6.032e-95 336.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria 28221|Deltaproteobacteria T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - Response_reg DYD1_k127_218188_3 1356852.N008_04425 5.056e-77 268.0 28HKZ@1|root,2Z7VP@2|Bacteria,4NFGM@976|Bacteroidetes,47JCW@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3050) - - - - - - - - - - - - DUF3050 DYD1_k127_218188_1 1123242.JH636435_gene1594 4.581e-132 436.0 COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes 203682|Planctomycetes C B12 binding domain - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM DYD1_k127_218188_9 37919.EP51_15095 5.481e-08 64.0 COG3396@1|root,COG3396@2|Bacteria,2GMBI@201174|Actinobacteria,4FUWX@85025|Nocardiaceae 201174|Actinobacteria C P-aminobenzoate N-oxygenase AurF - - - - - - - - - - - - AurF DYD1_k127_218188_8 377629.TERTU_2372 2.843e-12 77.0 COG0508@1|root,COG0508@2|Bacteria,1Q4SM@1224|Proteobacteria,1RR4G@1236|Gammaproteobacteria,2PPPU@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - - - - - - - - - - 2-oxoacid_dh DYD1_k127_218188_0 617140.AJZE01000004_gene3359 5.998e-154 499.0 COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria,1XTS2@135623|Vibrionales 135623|Vibrionales I reductase hmgA - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - HMG-CoA_red DYD1_k127_218188_7 1111069.TCCBUS3UF1_22080 1.119e-20 102.0 COG1597@1|root,COG1597@2|Bacteria,1WI0N@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I PFAM Diacylglycerol kinase, catalytic bmrU - - - - - - - - - - - DAGK_cat DYD1_k127_218188_5 313606.M23134_03117 1.588e-34 142.0 COG4589@1|root,COG4589@2|Bacteria,4NT8F@976|Bacteroidetes,47W0E@768503|Cytophagia 976|Bacteroidetes S Cytidylyltransferase family - - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 DYD1_k127_2205312_0 1379698.RBG1_1C00001G0508 9.718e-154 493.0 COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family bktB - 2.3.1.16,2.3.1.9 ko:K00626,ko:K07508 ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00085,M00087,M00088,M00095,M00373,M00374,M00375 R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747 RC00004,RC00326,RC00405,RC01702 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD1_k127_2205312_2 861299.J421_3379 2.491e-06 55.0 COG3809@1|root,COG3809@2|Bacteria 2|Bacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - Rhomboid,zf-TFIIB DYD1_k127_2205312_1 1379698.RBG1_1C00001G1462 5.046e-25 109.0 COG1545@1|root,COG1545@2|Bacteria 2|Bacteria I DUF35 OB-fold domain, acyl-CoA-associated - - - ko:K07068 - - - - ko00000 - - - DUF35_N,OB_aCoA_assoc DYD1_k127_221830_0 1382359.JIAL01000001_gene558 1.58e-139 450.0 COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia 204432|Acidobacteriia CE Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.41 ko:K00030 ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010 R00709 RC00114 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD1_k127_221830_2 1380347.JNII01000009_gene2009 9.159e-66 239.0 COG0006@1|root,COG0006@2|Bacteria 2|Bacteria E proline dipeptidase activity - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 DYD1_k127_221830_3 702113.PP1Y_AT33092 1.523e-55 207.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,2K1BU@204457|Sphingomonadales 204457|Sphingomonadales S PFAM amidohydrolase 2 - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_221830_1 1280949.HAD_16937 3.191e-69 257.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TR1E@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q amidohydrolase - - - - - - - - - - - - Amidohydro_3 DYD1_k127_221830_4 644968.DFW101_3321 2.856e-05 46.0 COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales 28221|Deltaproteobacteria T response regulator, receiver - - - - - - - - - - - - CBS,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg DYD1_k127_222974_5 455632.SGR_354 1.381e-17 92.0 COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria 201174|Actinobacteria Q Catalyzes the conversion of maleate to fumarate - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD1_k127_222974_4 443152.MDG893_15295 4.279e-50 193.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_222974_2 404589.Anae109_0937 1.516e-59 215.0 COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_11 DYD1_k127_222974_0 502025.Hoch_3329 6.69e-75 261.0 COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales 28221|Deltaproteobacteria L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku - - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku DYD1_k127_222974_1 189753.AXAS01000041_gene2534 8.577e-71 252.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_222974_7 391623.TERMP_00457 0.0004688 46.0 COG1656@1|root,COG2442@1|root,arCOG04290@2157|Archaea,arCOG07520@2157|Archaea,2Y1HG@28890|Euryarchaeota,244W7@183968|Thermococci 183968|Thermococci S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 DYD1_k127_222974_6 189753.AXAS01000041_gene2534 7.904e-14 79.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_222974_3 760568.Desku_3308 1.761e-56 202.0 COG4636@1|root,COG4636@2|Bacteria,1V3G7@1239|Firmicutes,24H2Z@186801|Clostridia,266ZP@186807|Peptococcaceae 186801|Clostridia S Putative restriction endonuclease - - - - - - - - - - - - HTH_17,Uma2 DYD1_k127_2237028_1 1333998.M2A_2787 5.561e-32 137.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria,4BSZR@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2237028_3 1380394.JADL01000010_gene4119 2.008e-16 85.0 COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2UGI0@28211|Alphaproteobacteria,2JZSK@204441|Rhodospirillales 204441|Rhodospirillales S Haem-degrading - - - - - - - - - - - - Haem_degrading DYD1_k127_2237028_0 443152.MDG893_15295 5.513e-59 217.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_2237028_2 485913.Krac_4142 9.533e-21 97.0 COG0346@1|root,COG0346@2|Bacteria,2G9TR@200795|Chloroflexi 200795|Chloroflexi E Glyoxalase-like domain - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD1_k127_2237028_4 331678.Cphamn1_0995 0.0002876 48.0 COG2885@1|root,COG2885@2|Bacteria,1FE7F@1090|Chlorobi 1090|Chlorobi M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,OmpA DYD1_k127_2262354_1 1218084.BBJK01000005_gene670 2.598e-90 310.0 COG1804@1|root,COG1804@2|Bacteria,1P68A@1224|Proteobacteria,2VZJW@28216|Betaproteobacteria,1K3IQ@119060|Burkholderiaceae 28216|Betaproteobacteria C CoA-transferase family III - - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 DYD1_k127_2262354_2 751944.HALDL1_10460 2.065e-46 182.0 COG2141@1|root,arCOG02410@2157|Archaea,2XU72@28890|Euryarchaeota,23S3D@183963|Halobacteria 183963|Halobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases mer2 - - - - - - - - - - - Bac_luciferase DYD1_k127_2262354_4 401526.TcarDRAFT_1449 2.031e-34 145.0 COG1099@1|root,COG1099@2|Bacteria,1V5KM@1239|Firmicutes,4H4YQ@909932|Negativicutes 909932|Negativicutes S with the TIM-barrel fold - - - - - - - - - - - - - DYD1_k127_2262354_0 443598.AUFA01000058_gene7306 4.433e-148 478.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,3K3T8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Cobalamin-independent synthase, Catalytic domain metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_2262354_3 381666.PHG174 1.451e-44 164.0 2E52W@1|root,32ZW3@2|Bacteria,1RIGH@1224|Proteobacteria,2VT9W@28216|Betaproteobacteria,1KDNK@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - UPF0158 DYD1_k127_2274089_0 909613.UO65_0943 4.553e-60 215.0 COG0664@1|root,COG0664@2|Bacteria,2INMI@201174|Actinobacteria,4EBXN@85010|Pseudonocardiales 201174|Actinobacteria K Cyclic nucleotide-monophosphate binding domain - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding DYD1_k127_2274089_2 1415779.JOMH01000001_gene3106 4.303e-11 69.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1X2XK@135614|Xanthomonadales 135614|Xanthomonadales O Cysteine desulfurase activator complex subunit SufB sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 DYD1_k127_2274089_1 671143.DAMO_1110 5.98e-12 76.0 2BHJK@1|root,32BN1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2275718_10 1121271.AUCM01000009_gene2235 4.959e-34 142.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - - DYD1_k127_2275718_14 1242864.D187_006155 1.496e-10 73.0 2CEXM@1|root,2ZG9T@2|Bacteria,1P6IQ@1224|Proteobacteria,433FZ@68525|delta/epsilon subdivisions,2WY1W@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2275718_11 685727.REQ_00750 1.69e-25 121.0 COG0624@1|root,COG0624@2|Bacteria,2I9Y6@201174|Actinobacteria,4FX57@85025|Nocardiaceae 201174|Actinobacteria E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - - - - - - - - - - - DYD1_k127_2275718_6 997296.PB1_10899 1.663e-71 257.0 COG0584@1|root,COG3540@1|root,COG0584@2|Bacteria,COG3540@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,1ZPVG@1386|Bacillus 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,PhoD,PhoD_N DYD1_k127_2275718_12 1132836.RCCGE510_11334 6.721e-24 105.0 COG0251@1|root,COG0251@2|Bacteria,1RH8Y@1224|Proteobacteria,2U9P4@28211|Alphaproteobacteria 28211|Alphaproteobacteria J endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD1_k127_2275718_13 266779.Meso_2921 2.316e-23 112.0 COG0715@1|root,COG0715@2|Bacteria,1RCBF@1224|Proteobacteria,2U6AN@28211|Alphaproteobacteria,43PC3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - - - - - - - - - - NMT1,NMT1_2 DYD1_k127_2275718_4 1187851.A33M_1060 2.365e-79 273.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,3FE0S@34008|Rhodovulum 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_2275718_9 1463857.JOFZ01000007_gene161 3.602e-39 156.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_2275718_7 266834.SMc02345 9.267e-46 175.0 COG0600@1|root,COG0600@2|Bacteria,1N4HG@1224|Proteobacteria,2TSTU@28211|Alphaproteobacteria,4BBHM@82115|Rhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_2275718_5 1519464.HY22_12475 3.233e-78 273.0 COG2404@1|root,COG2404@2|Bacteria,1FEPM@1090|Chlorobi 1090|Chlorobi S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - DYD1_k127_2275718_0 1382356.JQMP01000003_gene2139 1.073e-139 453.0 COG0686@1|root,COG0686@2|Bacteria,2G68X@200795|Chloroflexi,27YU4@189775|Thermomicrobia 189775|Thermomicrobia C Alanine dehydrogenase/PNT, N-terminal domain - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N DYD1_k127_2275718_8 177437.HRM2_01080 1.665e-45 167.0 COG2363@1|root,COG2363@2|Bacteria,1PX71@1224|Proteobacteria,434AX@68525|delta/epsilon subdivisions,2X3EE@28221|Deltaproteobacteria,2MP9J@213118|Desulfobacterales 28221|Deltaproteobacteria S Protein of unknown function (DUF423) - - - - - - - - - - - - DUF423 DYD1_k127_2275718_2 675635.Psed_3034 6.633e-117 393.0 COG5016@1|root,COG5016@2|Bacteria,2IA4P@201174|Actinobacteria 201174|Actinobacteria C Conserved carboxylase domain - - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - HMGL-like,PYC_OADA DYD1_k127_2275718_3 309801.trd_A0669 4.958e-84 287.0 COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi,27Y3J@189775|Thermomicrobia 189775|Thermomicrobia S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2275718_1 675635.Psed_3034 2.319e-118 398.0 COG5016@1|root,COG5016@2|Bacteria,2IA4P@201174|Actinobacteria 201174|Actinobacteria C Conserved carboxylase domain - - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - HMGL-like,PYC_OADA DYD1_k127_2281641_17 388051.AUFE01000063_gene5299 4.769e-10 67.0 2AGC9@1|root,316HY@2|Bacteria,1PXMI@1224|Proteobacteria,2WD0V@28216|Betaproteobacteria,1K8YX@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2281641_14 375286.mma_1189 7.954e-32 130.0 2E3QW@1|root,32YNQ@2|Bacteria,1NFBV@1224|Proteobacteria,2VWPZ@28216|Betaproteobacteria,477JM@75682|Oxalobacteraceae 28216|Betaproteobacteria S Periplasmic lysozyme inhibitor of I-type lysozyme - - - - - - - - - - - - PliI DYD1_k127_2281641_16 546274.EIKCOROL_01776 1.243e-16 89.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,2KPN9@206351|Neisseriales 206351|Neisseriales M Belongs to the ompA family yiaD - - - - - - - - - - - Gly-zipper_Omp,OmpA,Rick_17kDa_Anti DYD1_k127_2281641_6 335543.Sfum_1461 2.882e-91 310.0 COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,2MQWV@213462|Syntrophobacterales 28221|Deltaproteobacteria N Protein of unknown function (DUF2950) - - - - - - - - - - - - DUF2950 DYD1_k127_2281641_5 338966.Ppro_0417 3.469e-99 338.0 COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,42PA3@68525|delta/epsilon subdivisions,2WM6X@28221|Deltaproteobacteria,43SGF@69541|Desulfuromonadales 28221|Deltaproteobacteria M Protein of unknown function (DUF3300) - - - - - - - - - - - - DUF3300 DYD1_k127_2281641_15 1500306.JQLA01000003_gene4503 3.169e-19 102.0 2E560@1|root,32ZYT@2|Bacteria,1RD6P@1224|Proteobacteria,2UJ9J@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2281641_9 1121448.DGI_1413 1.598e-72 267.0 29D6U@1|root,3004T@2|Bacteria,1R9I1@1224|Proteobacteria,42T9I@68525|delta/epsilon subdivisions,2WPXB@28221|Deltaproteobacteria,2MADE@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2281641_12 196367.JNFG01000037_gene7583 2.38e-42 159.0 COG4566@1|root,COG4566@2|Bacteria,1MZ8E@1224|Proteobacteria,2VYAI@28216|Betaproteobacteria,1K8D8@119060|Burkholderiaceae 28216|Betaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_2281641_10 640511.BC1002_5532 9.917e-60 214.0 COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2VQH8@28216|Betaproteobacteria,1JZZ5@119060|Burkholderiaceae 28216|Betaproteobacteria K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg DYD1_k127_2281641_3 335543.Sfum_0581 3.338e-112 391.0 COG2202@1|root,COG2984@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - ABC_sub_bind,HATPase_c,HisKA,PAS_3 DYD1_k127_2281641_11 757424.Hsero_0010 5.088e-57 212.0 COG2207@1|root,COG2207@2|Bacteria,1PGUS@1224|Proteobacteria,2W9PE@28216|Betaproteobacteria,477R9@75682|Oxalobacteraceae 28216|Betaproteobacteria K Arabinose-binding domain of AraC transcription regulator, N-term - - - - - - - - - - - - Arabinose_bd,HTH_18 DYD1_k127_2281641_1 1287276.X752_16010 1.207e-150 492.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria 28211|Alphaproteobacteria C SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM DYD1_k127_2281641_0 909663.KI867149_gene3370 2.222e-179 583.0 COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_6 DYD1_k127_2281641_2 765420.OSCT_2288 4.484e-119 389.0 COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,375BG@32061|Chloroflexia 32061|Chloroflexia P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer DYD1_k127_2281641_8 522306.CAP2UW1_2891 4.786e-80 276.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VIN1@28216|Betaproteobacteria,1KR64@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria ET PFAM extracellular solute-binding protein family 3 aapJ - - ko:K02030,ko:K09969,ko:K10001 ko02010,ko02020,map02010,map02020 M00230,M00232,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 DYD1_k127_2281641_4 204669.Acid345_0914 1.609e-107 380.0 COG3264@1|root,COG3264@2|Bacteria,3Y5SA@57723|Acidobacteria,2JMSI@204432|Acidobacteriia 204432|Acidobacteriia M Mechanosensitive ion channel - - - ko:K05802 - - - - ko00000,ko02000 1.A.23.1.1 - - MS_channel DYD1_k127_2281641_7 335543.Sfum_3774 7.803e-87 316.0 COG3164@1|root,COG3164@2|Bacteria,1NSC1@1224|Proteobacteria,43CFQ@68525|delta/epsilon subdivisions,2X7QS@28221|Deltaproteobacteria,2MQQM@213462|Syntrophobacterales 28221|Deltaproteobacteria S AsmA-like C-terminal region - - - - - - - - - - - - AsmA_2,DUF3971 DYD1_k127_2335380_1 41431.PCC8801_3049 2.945e-45 171.0 COG1052@1|root,COG1052@2|Bacteria,1G1BP@1117|Cyanobacteria,3KI1Y@43988|Cyanothece 1117|Cyanobacteria C D-isomer specific 2-hydroxyacid dehydrogenase catalytic region - - 1.1.1.26,1.20.1.1 ko:K00015,ko:K18916 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_2335380_2 713587.THITH_05700 2.327e-41 154.0 COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,1SCNC@1236|Gammaproteobacteria,1X1DH@135613|Chromatiales 135613|Chromatiales S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 DYD1_k127_2335380_3 713587.THITH_05705 3.171e-28 119.0 COG3636@1|root,COG3636@2|Bacteria,1N2SE@1224|Proteobacteria,1T064@1236|Gammaproteobacteria 1236|Gammaproteobacteria K addiction module antidote protein - - - - - - - - - - - - - DYD1_k127_2335380_0 1266925.JHVX01000003_gene513 1.532e-255 796.0 COG2159@1|root,COG2159@2|Bacteria,1PUZA@1224|Proteobacteria,2VXX6@28216|Betaproteobacteria,372U5@32003|Nitrosomonadales 28216|Betaproteobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2335380_4 428125.CLOLEP_01064 3.248e-15 83.0 COG2159@1|root,COG2159@2|Bacteria,1TRU0@1239|Firmicutes,248VZ@186801|Clostridia,3WIHD@541000|Ruminococcaceae 186801|Clostridia S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2348797_17 502025.Hoch_0180 1.44e-30 126.0 COG2346@1|root,COG2346@2|Bacteria 2|Bacteria O COG2346, Truncated hemoglobins - - - ko:K06886 - - - - ko00000 - - - Bac_globin DYD1_k127_2348797_2 1123023.JIAI01000014_gene3659 1.09e-115 379.0 COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4DZYK@85010|Pseudonocardiales 201174|Actinobacteria E PFAM Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR DYD1_k127_2348797_0 398767.Glov_0757 1.186e-198 631.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon DYD1_k127_2348797_3 1125863.JAFN01000001_gene3405 4.715e-115 386.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria 28221|Deltaproteobacteria M lipoprotein releasing system, transmembrane protein, LolC E family lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD DYD1_k127_2348797_13 880072.Desac_2720 2.403e-68 241.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2MQF7@213462|Syntrophobacterales 28221|Deltaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran DYD1_k127_2348797_1 316067.Geob_2097 1.871e-160 534.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,43UEF@69541|Desulfuromonadales 28221|Deltaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA DYD1_k127_2348797_19 290397.Adeh_1082 2.199e-18 91.0 COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,2YVZ7@29|Myxococcales 28221|Deltaproteobacteria M Outer membrane protein (OmpH-like) - - - ko:K06142 - - - - ko00000 - - - OmpH DYD1_k127_2348797_5 56780.SYN_01568 2.936e-99 335.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,2MQC0@213462|Syntrophobacterales 28221|Deltaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD DYD1_k127_2348797_16 338966.Ppro_0342 3.416e-44 166.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,43UKW@69541|Desulfuromonadales 28221|Deltaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA DYD1_k127_2348797_9 1144275.COCOR_02671 8.733e-86 291.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep DYD1_k127_2348797_10 880072.Desac_2714 6.012e-85 289.0 COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,42P40@68525|delta/epsilon subdivisions,2WK7K@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF1009) - - - ko:K09949 - - - - ko00000 - - - DUF1009 DYD1_k127_2348797_7 1232410.KI421414_gene2842 4.573e-95 320.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales 28221|Deltaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold gnnA - - ko:K09949 - - - - ko00000 - - iAF987.Gmet_2352 GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_2348797_6 269799.Gmet_2350 3.582e-95 324.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,43SZS@69541|Desulfuromonadales 28221|Deltaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB DYD1_k127_2348797_11 338963.Pcar_1260 1.975e-81 292.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,43TBC@69541|Desulfuromonadales 28221|Deltaproteobacteria M 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) kdtA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N DYD1_k127_2348797_15 330214.NIDE3032 1.24e-49 190.0 COG1663@1|root,COG1663@2|Bacteria,3J0QN@40117|Nitrospirae 40117|Nitrospirae M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK DYD1_k127_2348797_14 891968.Anamo_1477 1.902e-51 188.0 COG0241@1|root,COG0241@2|Bacteria,3TB5N@508458|Synergistetes 508458|Synergistetes E 1,7-bisphosphate phosphatase - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_like DYD1_k127_2348797_4 1499967.BAYZ01000176_gene5652 1.04e-104 349.0 COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein ytcB - 5.1.3.2,5.1.3.6 ko:K01784,ko:K08679 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01385,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd DYD1_k127_2348797_8 1380394.JADL01000004_gene5909 8.821e-92 310.0 COG0346@1|root,COG0346@2|Bacteria,1MX75@1224|Proteobacteria,2TRQS@28211|Alphaproteobacteria,2JVNN@204441|Rhodospirillales 204441|Rhodospirillales E lactoylglutathione lyase activity - - - - - - - - - - - - - DYD1_k127_2348797_18 909663.KI867150_gene2324 5.791e-23 99.0 COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,2MSAY@213462|Syntrophobacterales 28221|Deltaproteobacteria S Belongs to the UPF0434 family - - - ko:K09791 - - - - ko00000 - - - Trm112p DYD1_k127_2348797_12 1125863.JAFN01000001_gene534 2.579e-73 259.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM glycosyl transferase family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_2349298_0 648757.Rvan_0037 8.988e-88 303.0 COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria 28211|Alphaproteobacteria E benzoyl-CoA reductase - - 1.3.7.8 ko:K04112 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D DYD1_k127_2349298_2 635013.TherJR_2344 6.999e-28 129.0 COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,262F6@186807|Peptococcaceae 186801|Clostridia H Molybdopterin-guanine dinucleotide biosynthesis mobB - 2.7.7.77 ko:K03753,ko:K13818 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - MobB,NTP_transf_3 DYD1_k127_2349298_1 589865.DaAHT2_0551 2.799e-52 203.0 COG2191@1|root,COG2191@2|Bacteria,1RBNI@1224|Proteobacteria,42QZP@68525|delta/epsilon subdivisions,2WMY0@28221|Deltaproteobacteria,2MJH4@213118|Desulfobacterales 28221|Deltaproteobacteria C FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - 1.2.7.12 ko:K11261 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R03015,R08060,R11743 RC00197,RC00323 ko00000,ko00001,ko00002,ko01000 - - - FmdE,zf-dskA_traR DYD1_k127_2349298_3 330214.NIDE3281 4.294e-22 104.0 2AKTZ@1|root,31BM1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2357165_0 330214.NIDE1291 1.431e-230 731.0 COG0210@1|root,COG0210@2|Bacteria,3J0VX@40117|Nitrospirae 40117|Nitrospirae L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD1_k127_2357165_1 867903.ThesuDRAFT_02355 2.077e-101 348.0 COG0421@1|root,COG0421@2|Bacteria,1UI4A@1239|Firmicutes,25GIE@186801|Clostridia 186801|Clostridia E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth DYD1_k127_2357165_5 237368.SCABRO_01528 4.773e-15 83.0 COG0457@1|root,COG0457@2|Bacteria 237368.SCABRO_01528|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_2357165_4 269799.Gmet_1369 7.139e-48 181.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD1_k127_2357165_3 443152.MDG893_15462 5.463e-63 223.0 COG1335@1|root,COG1335@2|Bacteria,1QK2B@1224|Proteobacteria,1RYRR@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Hydrolase - - - - - - - - - - - - Isochorismatase DYD1_k127_2357165_2 257310.BB0681 1.302e-95 322.0 COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2W02V@28216|Betaproteobacteria 28216|Betaproteobacteria L LVIVD repeat - - - - - - - - - - - - LVIVD DYD1_k127_2377655_0 76114.p2A120 7.21e-163 526.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_2377655_4 1382359.JIAL01000001_gene2144 9.438e-33 138.0 COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria,2JJ7J@204432|Acidobacteriia 204432|Acidobacteriia S Bifunctional nuclease - - - ko:K08999 - - - - ko00000 - - - DNase-RNase DYD1_k127_2377655_1 443143.GM18_3518 1.979e-126 424.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,43T6C@69541|Desulfuromonadales 28221|Deltaproteobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C DYD1_k127_2377655_3 269799.Gmet_2052 1.58e-89 306.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT DYD1_k127_2377655_2 566466.NOR53_3277 7.096e-106 359.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1SKMW@1236|Gammaproteobacteria,1J9PK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD1_k127_2381471_13 935866.JAER01000001_gene2709 4.615e-28 121.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 DYD1_k127_2381471_0 644966.Tmar_1686 0.0 1170.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia 186801|Clostridia C aconitate hydratase acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C DYD1_k127_2381471_7 1177181.T9A_00253 9.987e-48 182.0 COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG0491 Zn-dependent hydrolases, including glyoxylases blaB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,NUDIX DYD1_k127_2381471_12 1499967.BAYZ01000095_gene4122 2.136e-30 136.0 COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - - DYD1_k127_2381471_9 391615.ABSJ01000022_gene315 2.863e-40 158.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1J5ZU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR DYD1_k127_2381471_10 1396418.BATQ01000067_gene1672 2.135e-39 153.0 COG3000@1|root,COG3000@2|Bacteria 2|Bacteria I iron ion binding - - - - - - - - - - - - FA_hydroxylase,Polyketide_cyc2 DYD1_k127_2381471_5 671143.DAMO_2401 4.447e-96 324.0 COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg DYD1_k127_2381471_8 338966.Ppro_2672 1.207e-44 169.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,43US0@69541|Desulfuromonadales 28221|Deltaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC DYD1_k127_2381471_6 335543.Sfum_0994 1.531e-48 180.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,2MQJQ@213462|Syntrophobacterales 28221|Deltaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N DYD1_k127_2381471_2 1131269.AQVV01000002_gene1185 1.336e-142 460.0 COG2255@1|root,COG2255@2|Bacteria 2|Bacteria L four-way junction helicase activity ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N DYD1_k127_2381471_15 316067.Geob_2318 5.169e-21 93.0 COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,42WU5@68525|delta/epsilon subdivisions,2WRRS@28221|Deltaproteobacteria,43SRB@69541|Desulfuromonadales 28221|Deltaproteobacteria H Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 DYD1_k127_2381471_1 1232410.KI421415_gene3124 2.696e-217 697.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales 28221|Deltaproteobacteria T PAS domain ntrY - 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 DYD1_k127_2381471_3 909663.KI867151_gene3132 5.424e-118 394.0 COG0774@1|root,COG2204@1|root,COG0774@2|Bacteria,COG2204@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria,2MRFZ@213462|Syntrophobacterales 28221|Deltaproteobacteria MT UDP-3-O-acyl N-acetylglycosamine deacetylase lpxC - 3.5.1.108 ko:K02535,ko:K13599 ko00540,ko01100,ko02020,map00540,map01100,map02020 M00060,M00498 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005,ko02022 - - - LpxC DYD1_k127_2381471_14 498848.TaqDRAFT_4728 4.438e-22 102.0 COG4911@1|root,COG4911@2|Bacteria,1WJWB@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Uncharacterized conserved protein (DUF2203) - - - - - - - - - - - - DUF2203 DYD1_k127_2381471_4 314230.DSM3645_24650 8.957e-103 346.0 COG1600@1|root,COG1600@2|Bacteria,2IX4H@203682|Planctomycetes 203682|Planctomycetes C Fe-S protein - - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 DYD1_k127_2381471_11 1121405.dsmv_3242 1.072e-35 140.0 COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2MMDF@213118|Desulfobacterales 28221|Deltaproteobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 DYD1_k127_2399853_9 1121121.KB894315_gene1793 8.913e-09 62.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,274G5@186822|Paenibacillaceae 91061|Bacilli C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_2399853_8 748727.CLJU_c25380 1.441e-13 82.0 COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,24A2V@186801|Clostridia,36FHT@31979|Clostridiaceae 186801|Clostridia P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K15598 ko02010,map02010 M00442 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.3,3.A.1.17.6 - - NMT1 DYD1_k127_2399853_3 243233.MCA1758 1.525e-44 171.0 2BXI0@1|root,2Z9A2@2|Bacteria,1R9XN@1224|Proteobacteria,1S39A@1236|Gammaproteobacteria,1XGER@135618|Methylococcales 135618|Methylococcales S Protein of unknown function (DUF2459) - - - - - - - - - - - - DUF2459 DYD1_k127_2399853_12 342949.PNA2_1862 1.654e-06 57.0 COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci 183968|Thermococci J Endoribonuclease L-PSP - GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP DYD1_k127_2399853_5 296591.Bpro_3359 1.428e-37 145.0 COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria 28216|Betaproteobacteria E ACT domain - - - - - - - - - - - - ACT,ACT_6 DYD1_k127_2399853_7 398767.Glov_1255 7.168e-18 95.0 COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria,43S55@69541|Desulfuromonadales 28221|Deltaproteobacteria S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase DYD1_k127_2399853_11 1430331.EP10_00755 1.65e-06 57.0 COG0793@1|root,COG3409@1|root,COG0793@2|Bacteria,COG3409@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1WEHI@129337|Geobacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpB GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 DYD1_k127_2399853_4 1037409.BJ6T_20700 3.235e-42 161.0 COG0662@1|root,COG0662@2|Bacteria,1R4UW@1224|Proteobacteria,2TYFA@28211|Alphaproteobacteria 28211|Alphaproteobacteria G 3-hydroxyanthranilic acid dioxygenase - - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO DYD1_k127_2399853_0 1131269.AQVV01000028_gene28 2.04e-120 426.0 COG0421@1|root,COG0421@2|Bacteria 2|Bacteria E spermidine synthase activity speE GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synt_N,Spermine_synth DYD1_k127_2399853_1 237368.SCABRO_00411 1.363e-80 277.0 COG0345@1|root,COG0345@2|Bacteria,2IY5U@203682|Planctomycetes 203682|Planctomycetes E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer DYD1_k127_2399853_10 383372.Rcas_1215 2.615e-08 62.0 COG0791@1|root,COG3807@1|root,COG0791@2|Bacteria,COG3807@2|Bacteria,2G99E@200795|Chloroflexi,3759J@32061|Chloroflexia 32061|Chloroflexia M SH3, type 3 domain protein - - - - - - - - - - - - NLPC_P60,SH3_3 DYD1_k127_2399853_2 1232410.KI421419_gene2520 3.201e-45 173.0 COG3784@1|root,COG3784@2|Bacteria,1MYIH@1224|Proteobacteria,42TUM@68525|delta/epsilon subdivisions,2WQJJ@28221|Deltaproteobacteria,43V1R@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF1318) - - - - - - - - - - - - DUF1318 DYD1_k127_2399853_6 637390.AFOH01000029_gene1359 4.226e-33 149.0 COG2911@1|root,COG2911@2|Bacteria,1MW9V@1224|Proteobacteria,1S3FX@1236|Gammaproteobacteria,2NCS9@225057|Acidithiobacillales 225057|Acidithiobacillales S Protein conserved in bacteria - - - - - - - - - - - - - DYD1_k127_2403739_1 439235.Dalk_1881 4.805e-16 82.0 COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Tetratricopeptide repeat - - - - - - - - - - - - PMT_2 DYD1_k127_2403739_0 880072.Desac_1406 4.947e-202 638.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2MQ8V@213462|Syntrophobacterales 28221|Deltaproteobacteria H Belongs to the UbiD family - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_2403739_2 1265505.ATUG01000001_gene4162 7.302e-05 46.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,2MITG@213118|Desulfobacterales 28221|Deltaproteobacteria H 4-hydroxybenzoate polyprenyltransferase ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD1_k127_2409531_1 671143.DAMO_2383 2.817e-181 568.0 COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria 2|Bacteria O FeS assembly protein SufB sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - ko:K07033,ko:K09014 - - - - ko00000 - - iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 UPF0051 DYD1_k127_2409531_7 1122915.AUGY01000118_gene6526 1.611e-09 63.0 COG0715@1|root,COG0715@2|Bacteria,1UZYY@1239|Firmicutes,4HE24@91061|Bacilli,26RHH@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_2409531_9 5016.M2TAG0 3.196e-07 57.0 COG2159@1|root,KOG4245@2759|Eukaryota,38KTN@33154|Opisthokonta,3NY88@4751|Fungi,3QS8G@4890|Ascomycota,209BT@147541|Dothideomycetes 4751|Fungi S Amidohydrolase - - 4.1.1.52 ko:K22213 - - - - ko00000,ko01000 - - - Amidohydro_2 DYD1_k127_2409531_8 457396.CSBG_00873 3.87e-08 59.0 COG0346@1|root,COG0346@2|Bacteria,1VD8Q@1239|Firmicutes,24JY7@186801|Clostridia,36K1K@31979|Clostridiaceae 186801|Clostridia E Glyoxalase bleomycin resistance protein dioxygenase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD1_k127_2409531_5 640512.BC1003_1916 5.937e-28 114.0 COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2VVVU@28216|Betaproteobacteria,1K9RD@119060|Burkholderiaceae 28216|Betaproteobacteria S Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin DYD1_k127_2409531_3 690850.Desaf_0959 1.637e-126 415.0 COG2327@1|root,COG2327@2|Bacteria,1R9R8@1224|Proteobacteria,42U55@68525|delta/epsilon subdivisions,2WQGP@28221|Deltaproteobacteria,2MDZ8@213115|Desulfovibrionales 28221|Deltaproteobacteria S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans DYD1_k127_2409531_0 247490.KSU1_D0482 2.878e-218 685.0 COG0644@1|root,COG0644@2|Bacteria 2|Bacteria C geranylgeranyl reductase activity - - - - - - - - - - - - FAD_oxidored DYD1_k127_2409531_2 518766.Rmar_2749 1.16e-144 474.0 COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,1FIZI@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD1_k127_2409531_6 645991.Sgly_3222 1.644e-17 95.0 COG3409@1|root,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,24965@186801|Clostridia,261US@186807|Peptococcaceae 186801|Clostridia M peptidoglycan-binding domain-containing protein - - - - - - - - - - - - LysM,NLPC_P60,PG_binding_1 DYD1_k127_2409531_4 1173027.Mic7113_2785 7.239e-103 368.0 COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_2425100_0 1120936.KB907220_gene1953 1.491e-66 244.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,4EK24@85012|Streptosporangiales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_2425100_2 1463857.JOFZ01000002_gene4841 2.7e-17 94.0 COG1840@1|root,COG1840@2|Bacteria,2I8NK@201174|Actinobacteria 201174|Actinobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11,SBP_bac_6,SBP_bac_8 DYD1_k127_2425100_1 1231391.AMZF01000008_gene1529 1.176e-28 124.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_2430292_2 448385.sce2679 1.841e-135 468.0 COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria,2YZ0R@29|Myxococcales 28221|Deltaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Response_reg DYD1_k127_2430292_0 62928.azo2788 1.13e-173 551.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,2KU9M@206389|Rhodocyclales 206389|Rhodocyclales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 DYD1_k127_2430292_1 497964.CfE428DRAFT_4013 6.961e-160 512.0 COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia 74201|Verrucomicrobia L DEAD DEAH box helicase domain protein - - - - - - - - - - - - DEAD,Helicase_C DYD1_k127_2430292_3 1173026.Glo7428_0087 1.202e-37 144.0 COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria 1117|Cyanobacteria O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD1_k127_2450233_18 1121127.JAFA01000004_gene1333 3.634e-07 59.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,1K17A@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA,TctB DYD1_k127_2450233_2 1123229.AUBC01000005_gene590 1.415e-143 470.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - TctA DYD1_k127_2450233_12 1410620.SHLA_91c000050 2.114e-34 146.0 COG3181@1|root,COG3181@2|Bacteria,1MWVK@1224|Proteobacteria,2TXW7@28211|Alphaproteobacteria,4B8R1@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_2450233_17 1216976.AX27061_0330 1.859e-07 62.0 COG0715@1|root,COG0715@2|Bacteria,1MV9S@1224|Proteobacteria,2VH5V@28216|Betaproteobacteria,3T849@506|Alcaligenaceae 28216|Betaproteobacteria P NMT1-like family ssuA1 - - ko:K15553 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 - - NMT1,NMT1_2 DYD1_k127_2450233_19 1234664.AMRO01000035_gene2707 2.014e-05 52.0 COG0662@1|root,COG0662@2|Bacteria,1VE4V@1239|Firmicutes 1239|Firmicutes G Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_2450233_14 667014.Thein_0931 3.385e-20 94.0 COG2331@1|root,COG2331@2|Bacteria,2GI3F@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 DYD1_k127_2450233_9 1041146.ATZB01000008_gene2208 6.802e-58 210.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,4B7AF@82115|Rhizobiaceae 28211|Alphaproteobacteria Q dienelactone hydrolase dlhH - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_2450233_15 1123376.AUIU01000014_gene616 4.982e-20 93.0 2EK9R@1|root,33E01@2|Bacteria,3J1B5@40117|Nitrospirae 40117|Nitrospirae - - - - - - - - - - - - - - - DYD1_k127_2450233_10 13689.BV96_03926 4.655e-54 201.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2TU8W@28211|Alphaproteobacteria,2K0IC@204457|Sphingomonadales 204457|Sphingomonadales I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_2450233_11 1131269.AQVV01000016_gene1868 1.731e-39 152.0 COG1310@1|root,COG1310@2|Bacteria 2|Bacteria S proteolysis - - 2.7.7.80,2.8.1.11,3.13.1.6 ko:K21140,ko:K21147 ko04122,map04122 - R07459,R07461,R11524 RC00043,RC00064,RC00090 ko00000,ko00001,ko01000 - - - Prok-JAB,Rhodanese,ThiF DYD1_k127_2450233_13 1144275.COCOR_04962 7.891e-21 100.0 COG0741@1|root,COG0741@2|Bacteria,1N1GB@1224|Proteobacteria,42X1K@68525|delta/epsilon subdivisions,2WTCI@28221|Deltaproteobacteria 28221|Deltaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT DYD1_k127_2450233_3 76114.p2A102 1.999e-115 385.0 COG1804@1|root,COG1804@2|Bacteria,1NSWZ@1224|Proteobacteria,2WFDZ@28216|Betaproteobacteria 28216|Betaproteobacteria C CoA-transferase family III - - 2.8.3.15 ko:K07544 ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220 M00418 R05588 RC00014,RC00137 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 DYD1_k127_2450233_5 76114.p2A104 4.692e-100 341.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria 28216|Betaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_2450233_0 76114.p2A133 1.408e-252 788.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2W317@28216|Betaproteobacteria 28216|Betaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_2450233_8 1134413.ANNK01000135_gene3127 3.223e-58 211.0 COG1335@1|root,COG1335@2|Bacteria,1VA32@1239|Firmicutes,4HKVT@91061|Bacilli,1ZHJR@1386|Bacillus 91061|Bacilli Q Isochorismatase family - - - - - - - - - - - - Isochorismatase DYD1_k127_2450233_16 647113.Metok_0586 1.428e-09 70.0 COG0477@1|root,arCOG00130@2157|Archaea,2XT83@28890|Euryarchaeota,23Q2W@183939|Methanococci 183939|Methanococci G PFAM major facilitator superfamily MFS_1 - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr DYD1_k127_2450233_1 1380394.JADL01000009_gene3144 4.641e-161 514.0 COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,2JXDQ@204441|Rhodospirillales 204441|Rhodospirillales S NHL repeat - - - - - - - - - - - - NHL DYD1_k127_2450233_6 266117.Rxyl_0283 5.79e-94 315.0 COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CQ3S@84995|Rubrobacteria 84995|Rubrobacteria S Domain of unknown function (DUF427) - - - - - - - - - - - - NTP_transf_9 DYD1_k127_2450233_4 1192034.CAP_4624 1.402e-109 362.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PVS@68525|delta/epsilon subdivisions,2WJ7B@28221|Deltaproteobacteria,2YXQQ@29|Myxococcales 28221|Deltaproteobacteria E Glucose dehydrogenase C-terminus - - - - - - - - - - - - ADH_N,ADH_zinc_N,Glu_dehyd_C DYD1_k127_2450233_7 880073.Calab_1201 7.177e-78 274.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_2470338_19 309807.SRU_2769 1.207e-05 49.0 COG2128@1|root,COG2128@2|Bacteria,4NN22@976|Bacteroidetes,1FK4T@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S PA26 p53-induced protein (sestrin) - - - - - - - - - - - - CMD DYD1_k127_2470338_16 204669.Acid345_3238 1.248e-11 69.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity MA20_26500 - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD DYD1_k127_2470338_10 926549.KI421517_gene3213 1.507e-39 151.0 COG2259@1|root,COG2259@2|Bacteria,4PB3J@976|Bacteroidetes,47V4B@768503|Cytophagia 976|Bacteroidetes S DoxX - - - - - - - - - - - - DoxX DYD1_k127_2470338_13 1122247.C731_3601 6.448e-18 89.0 29XQK@1|root,30JGA@2|Bacteria,2IGVS@201174|Actinobacteria,2390P@1762|Mycobacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_2470338_22 1122214.AQWH01000011_gene2135 0.000393 48.0 COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components MA20_34190 - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_2470338_8 264198.Reut_A2355 5.484e-45 172.0 COG2059@1|root,COG2059@2|Bacteria,1MZHQ@1224|Proteobacteria,2WFNW@28216|Betaproteobacteria,1KFZS@119060|Burkholderiaceae 28216|Betaproteobacteria P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD1_k127_2470338_9 748280.NH8B_3402 9.425e-40 162.0 COG2059@1|root,COG2059@2|Bacteria,1RAZW@1224|Proteobacteria,2WFNV@28216|Betaproteobacteria,2KRJH@206351|Neisseriales 206351|Neisseriales P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD1_k127_2470338_7 479434.Sthe_3043 3.67e-45 177.0 COG0111@1|root,COG0111@2|Bacteria 2|Bacteria EH 4-phosphoerythronate dehydrogenase activity - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_2470338_5 1279017.AQYJ01000029_gene3723 2.729e-46 171.0 COG1917@1|root,COG1917@2|Bacteria,1R5IE@1224|Proteobacteria,1S3I4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_2470338_11 1957.JODX01000033_gene18 7.444e-33 134.0 COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function (DUF664) - - - - - - - - - - - - DUF664,DinB_2 DYD1_k127_2470338_15 1005999.GLGR_2939 1.874e-12 74.0 2EFPB@1|root,31ZAM@2|Bacteria,1MYWY@1224|Proteobacteria,1S7T8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2470338_17 1403819.BATR01000103_gene3436 1.414e-10 68.0 2A090@1|root,30NCA@2|Bacteria,46XPV@74201|Verrucomicrobia,2IWCA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S GtrA-like protein - - - - - - - - - - - - GtrA DYD1_k127_2470338_12 272123.Anacy_1171 1.389e-30 125.0 COG0346@1|root,COG0346@2|Bacteria,1G62I@1117|Cyanobacteria,1HP4U@1161|Nostocales 1117|Cyanobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_2470338_6 1100720.ALKN01000052_gene507 1.2e-45 181.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria 1224|Proteobacteria G Major facilitator Superfamily MA20_02120 - - - - - - - - - - - MFS_1 DYD1_k127_2470338_0 886293.Sinac_1681 4.122e-103 350.0 COG2358@1|root,COG2358@2|Bacteria,2IY5Z@203682|Planctomycetes 203682|Planctomycetes S NMT1-like family - - - - - - - - - - - - NMT1_3 DYD1_k127_2470338_14 1463857.JOFZ01000002_gene4841 1.735e-14 85.0 COG1840@1|root,COG1840@2|Bacteria,2I8NK@201174|Actinobacteria 201174|Actinobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11,SBP_bac_6,SBP_bac_8 DYD1_k127_2470338_2 1121438.JNJA01000001_gene2449 4.294e-63 229.0 COG0715@1|root,COG0715@2|Bacteria,1MZ8F@1224|Proteobacteria,42Q55@68525|delta/epsilon subdivisions,2WK81@28221|Deltaproteobacteria,2MAAX@213115|Desulfovibrionales 28221|Deltaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_2470338_1 65497.JODV01000003_gene4776 2.781e-76 263.0 COG1116@1|root,COG1116@2|Bacteria,2GM73@201174|Actinobacteria,4E9GC@85010|Pseudonocardiales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_2470338_4 1231391.AMZF01000022_gene1236 4.354e-50 189.0 COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,2VJ3H@28216|Betaproteobacteria,3T560@506|Alcaligenaceae 28216|Betaproteobacteria U ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050,ko:K15554 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - BPD_transp_1 DYD1_k127_2470338_3 1231391.AMZF01000022_gene1236 6.945e-51 198.0 COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,2VJ3H@28216|Betaproteobacteria,3T560@506|Alcaligenaceae 28216|Betaproteobacteria U ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050,ko:K15554 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - BPD_transp_1 DYD1_k127_2470338_21 1298867.AUES01000008_gene5160 9.764e-05 46.0 COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria,3K3FV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase DYD1_k127_2475645_2 697281.Mahau_1570 7.835e-76 264.0 COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,247YC@186801|Clostridia,42HUN@68295|Thermoanaerobacterales 186801|Clostridia M PFAM polysaccharide biosynthesis protein CapD pseB - 4.2.1.115,5.1.3.2 ko:K15894,ko:K17716 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00362 R00291,R09697 RC00289,RC02609 ko00000,ko00001,ko00002,ko01000 - - - Polysacc_synt_2 DYD1_k127_2475645_5 565033.GACE_1120 1.15e-55 206.0 COG1091@1|root,arCOG01367@2157|Archaea,2XVV7@28890|Euryarchaeota,245XF@183980|Archaeoglobi 183980|Archaeoglobi M TIGRFAM dTDP-4-dehydrorhamnose reductase - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind DYD1_k127_2475645_9 1131269.AQVV01000015_gene2044 1.029e-30 125.0 COG1898@1|root,COG1898@2|Bacteria 2|Bacteria M dTDP-4-dehydrorhamnose 3,5-epimerase activity fnlB - 1.1.1.367 ko:K19068 - - - - ko00000,ko01000 - - - Epimerase DYD1_k127_2475645_10 760568.Desku_2099 1.142e-18 98.0 COG1216@1|root,COG1216@2|Bacteria,1VE3R@1239|Firmicutes 1239|Firmicutes S Glycosyl Transferase - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_2475645_8 247490.KSU1_A0010 1.951e-40 159.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_24 DYD1_k127_2475645_1 247490.KSU1_D0287 1.087e-78 274.0 COG1216@1|root,COG1216@2|Bacteria,2IZV9@203682|Planctomycetes 203682|Planctomycetes S Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_2475645_6 243233.MCA2126 1.447e-49 190.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RXGH@1236|Gammaproteobacteria,1XG2N@135618|Methylococcales 135618|Methylococcales M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4 DYD1_k127_2475645_3 335543.Sfum_3634 1.55e-75 265.0 COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,2MQGF@213462|Syntrophobacterales 28221|Deltaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF987.Gmet_0922 CTP_transf_like,PfkB DYD1_k127_2475645_7 386415.NT01CX_2251 1.798e-45 175.0 COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,36ED0@31979|Clostridiaceae 186801|Clostridia S tigr00255 yicC - - - - - - - - - - - DUF1732,YicC_N DYD1_k127_2475645_4 338963.Pcar_1285 7.638e-58 210.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,43SG2@69541|Desulfuromonadales 28221|Deltaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin DYD1_k127_2475645_0 316067.Geob_2145 1.386e-271 856.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,43SZI@69541|Desulfuromonadales 28221|Deltaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS DYD1_k127_2494677_5 335543.Sfum_2178 8.694e-09 59.0 COG4295@1|root,COG4295@2|Bacteria,1RK74@1224|Proteobacteria,4307D@68525|delta/epsilon subdivisions,2WVHI@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2263) - - - - - - - - - - - - DUF2263 DYD1_k127_2494677_2 925775.XVE_1540 2.009e-41 161.0 COG4923@1|root,COG4923@2|Bacteria,1MY1R@1224|Proteobacteria,1SQHQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Protein of unknown function (DUF429) - - - - - - - - - - - - DUF429 DYD1_k127_2494677_3 56110.Oscil6304_0162 2.245e-30 121.0 COG5428@1|root,COG5428@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2283) - - - - - - - - - - - - DUF2283 DYD1_k127_2494677_0 1286106.MPL1_09265 2.146e-131 424.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,45ZYK@72273|Thiotrichales 72273|Thiotrichales O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 DYD1_k127_2494677_1 1278073.MYSTI_04802 7.501e-112 377.0 COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria 1224|Proteobacteria Q 4-hydroxyphenylacetate - - 1.14.14.9 ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 - R02698,R03299 RC00046 ko00000,ko00001,ko01000 - - - HpaB,HpaB_N DYD1_k127_250049_3 1173028.ANKO01000227_gene1237 1.518e-42 159.0 2CCSR@1|root,32RWC@2|Bacteria,1GA04@1117|Cyanobacteria,1HDA0@1150|Oscillatoriales 1117|Cyanobacteria S PFAM S23 ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_250049_0 671143.DAMO_2383 8.425e-279 861.0 COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria 2|Bacteria O FeS assembly protein SufB sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - ko:K07033,ko:K09014 - - - - ko00000 - - iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 UPF0051 DYD1_k127_250049_2 1122915.AUGY01000118_gene6542 1.715e-74 259.0 COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 DYD1_k127_250049_4 290397.Adeh_4190 7.11e-08 58.0 COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria,2Z0RF@29|Myxococcales 28221|Deltaproteobacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - zf-TFIIB DYD1_k127_250049_1 671143.DAMO_0975 1.311e-245 774.0 COG0465@1|root,COG0465@2|Bacteria,2NP22@2323|unclassified Bacteria 2|Bacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD1_k127_2507054_0 886293.Sinac_7530 1.033e-140 459.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_2507054_1 266117.Rxyl_0504 3.055e-112 374.0 COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4CSCW@84995|Rubrobacteria 84995|Rubrobacteria G Glucose Sorbosone dehydrogenase - - - - - - - - - - - - GSDH DYD1_k127_2507054_2 1120948.KB903224_gene354 2.527e-64 235.0 COG1052@1|root,COG1052@2|Bacteria,2I2IC@201174|Actinobacteria,4E09H@85010|Pseudonocardiales 201174|Actinobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_2634384_0 1110502.TMO_0012 9.007e-34 144.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2634384_1 1317118.ATO8_20854 3.789e-29 126.0 COG1028@1|root,COG1028@2|Bacteria,1PHZS@1224|Proteobacteria,2V7SZ@28211|Alphaproteobacteria,4KNY6@93682|Roseivivax 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 DYD1_k127_2634384_2 1499967.BAYZ01000154_gene1443 4.386e-07 55.0 COG1529@1|root,COG1529@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity xdh - 1.17.1.4 ko:K00087,ko:K12528 ko00230,ko00450,ko01100,ko01120,map00230,map00450,map01100,map01120 M00546 R01768,R02103,R07229 RC00143,RC02420 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD1_k127_2636921_8 926564.KI911619_gene3975 1.395e-06 51.0 2E4G6@1|root,32ZBB@2|Bacteria,2GR6E@201174|Actinobacteria,4F5WF@85017|Promicromonosporaceae 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_2636921_0 204669.Acid345_3726 1.987e-66 230.0 COG1018@1|root,COG1018@2|Bacteria 2|Bacteria C nitric oxide dioxygenase activity hmp - 1.14.12.17 ko:K05916 ko05132,map05132 - - - ko00000,ko00001,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 DYD1_k127_2636921_4 67315.JOBD01000068_gene3037 2.439e-28 127.0 COG0604@1|root,COG0604@2|Bacteria,2I9BF@201174|Actinobacteria 201174|Actinobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 DYD1_k127_2636921_7 935840.JAEQ01000008_gene729 1.79e-08 59.0 COG1018@1|root,COG1018@2|Bacteria,1R5FN@1224|Proteobacteria,2U080@28211|Alphaproteobacteria,43JW2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Oxidoreductase FAD-binding domain - - - - - - - - - - - - FAD_binding_6,NAD_binding_1 DYD1_k127_2636921_5 935567.JAES01000019_gene1061 1.737e-23 108.0 2E32R@1|root,32Y2Y@2|Bacteria,1NJNP@1224|Proteobacteria,1SQDR@1236|Gammaproteobacteria,1X847@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD1_k127_2636921_1 671143.DAMO_2097 2.239e-66 235.0 COG2853@1|root,COG2853@2|Bacteria,2NRQC@2323|unclassified Bacteria 2|Bacteria M MlaA lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA DYD1_k127_2636921_6 485913.Krac_6490 7.842e-17 86.0 COG1028@1|root,COG1028@2|Bacteria 485913.Krac_6490|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - DYD1_k127_2636921_3 671143.DAMO_2217 1.325e-53 196.0 COG2854@1|root,COG2854@2|Bacteria 2|Bacteria Q intermembrane phospholipid transfer - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD1_k127_2636921_2 237368.SCABRO_03058 6.989e-65 233.0 COG1216@1|root,COG1216@2|Bacteria,2IZV9@203682|Planctomycetes 203682|Planctomycetes S Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_2637499_5 204669.Acid345_3258 2.966e-11 64.0 COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia 204432|Acidobacteriia S PFAM Iron sulphur-containing domain, CDGSH-type - - - - - - - - - - - - zf-CDGSH DYD1_k127_2637499_3 247490.KSU1_C0965 1.79e-30 132.0 COG0643@1|root,COG0643@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K03320,ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035 1.A.11 - - Ammonium_transp,CheW,EAL,GGDEF,HATPase_c,Hpt,PilJ DYD1_k127_2637499_4 247490.KSU1_C0975 2.442e-20 101.0 2EFCU@1|root,3395Q@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2637499_0 1382359.JIAL01000001_gene52 1.185e-136 445.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH,HNH_2,RRXRR DYD1_k127_2637499_1 1382359.JIAL01000001_gene53 4.954e-90 306.0 28Q1U@1|root,2ZCK2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - NTP_transf_2 DYD1_k127_2637499_2 1382359.JIAL01000001_gene54 1.368e-57 208.0 COG3012@1|root,COG3012@2|Bacteria 2|Bacteria - - CP_0561 - - - - - - - - - - - DUF1186 DYD1_k127_2637499_6 323261.Noc_2515 8.287e-09 57.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales 135613|Chromatiales L TIGRFAM Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD1_k127_2643554_1 1267533.KB906734_gene4111 1.755e-47 174.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - CHRD,Cupin_2 DYD1_k127_2643554_0 1502851.FG93_03415 2.729e-63 224.0 COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,3JRP5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family MA20_37085 - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Ubie_methyltran DYD1_k127_2643554_2 365046.Rta_20260 5.726e-40 158.0 COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2VMGM@28216|Betaproteobacteria,4ABY0@80864|Comamonadaceae 28216|Betaproteobacteria ET SMART Extracellular solute-binding protein, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD1_k127_2671729_1 686340.Metal_3155 3.317e-62 222.0 2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales 135618|Methylococcales S Ceramidase - - - - - - - - - - - - Ceramidase DYD1_k127_2671729_2 306281.AJLK01000113_gene466 1.689e-48 182.0 COG1247@1|root,COG1247@2|Bacteria,1G5X1@1117|Cyanobacteria 1117|Cyanobacteria M Acetyltransferase, gnat family - - - - - - - - - - - - Acetyltransf_1,FR47 DYD1_k127_2671729_3 1122604.JONR01000023_gene4175 6.967e-22 102.0 COG4194@1|root,COG4194@2|Bacteria,1QTGM@1224|Proteobacteria,1SVXJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1648) - - - - - - - - - - - - DUF1648 DYD1_k127_2671729_0 1031711.RSPO_c03180 7.346e-75 255.0 COG4101@1|root,COG4101@2|Bacteria,1RB8W@1224|Proteobacteria,2VPF8@28216|Betaproteobacteria,1K4JK@119060|Burkholderiaceae 28216|Betaproteobacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 DYD1_k127_2671729_4 398578.Daci_4290 6.636e-08 55.0 COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2VMQJ@28216|Betaproteobacteria,4AEJ5@80864|Comamonadaceae 28216|Betaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.156,4.2.1.42 ko:K20023 ko00053,map00053 - R05608 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N DYD1_k127_2677338_0 765912.Thimo_1619 0.0 1344.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1WW62@135613|Chromatiales 135613|Chromatiales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon DYD1_k127_2677338_2 1041522.MCOL_V209005 4.625e-43 171.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2677338_1 1134413.ANNK01000086_gene318 1.412e-60 220.0 COG0715@1|root,COG0715@2|Bacteria,1TXP3@1239|Firmicutes,4I6PJ@91061|Bacilli,1ZM9Z@1386|Bacillus 91061|Bacilli P NMT1/THI5 like - - - - - - - - - - - - NMT1 DYD1_k127_2687196_0 886293.Sinac_5855 0.0 1106.0 COG3280@1|root,COG3280@2|Bacteria,2IYFT@203682|Planctomycetes 203682|Planctomycetes G Alpha amylase, catalytic domain - - 5.4.99.15 ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R09995 - ko00000,ko00001,ko00002,ko01000 - GH13 - Alpha-amylase DYD1_k127_2687196_1 1192034.CAP_6251 2.589e-101 342.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_2687196_7 1038860.AXAP01000097_gene5007 2.221e-26 121.0 COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_2687196_2 1211115.ALIQ01000238_gene3256 6.643e-97 326.0 COG2242@1|root,COG2242@2|Bacteria,1R0I9@1224|Proteobacteria,2TZR6@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD1_k127_2687196_5 1221522.B723_18525 2.873e-65 231.0 COG0600@1|root,COG0600@2|Bacteria,1MVD2@1224|Proteobacteria,1S8P8@1236|Gammaproteobacteria 1236|Gammaproteobacteria P binding-protein-dependent transport systems inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_2687196_8 864069.MicloDRAFT_00046360 1.951e-24 116.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,1JTV0@119045|Methylobacteriaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_2687196_4 936455.KI421499_gene61 1.353e-79 273.0 COG1116@1|root,COG1116@2|Bacteria,1N7FP@1224|Proteobacteria,2U19G@28211|Alphaproteobacteria,3JUI5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_2687196_6 1460634.JCM19037_1983 3.822e-58 214.0 COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli 91061|Bacilli S metal-dependent hydrolase of the TIM-barrel fold - - 4.1.1.45,4.1.1.52 ko:K03392,ko:K22213 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_2687196_3 1211115.ALIQ01000238_gene3256 6.673e-93 312.0 COG2242@1|root,COG2242@2|Bacteria,1R0I9@1224|Proteobacteria,2TZR6@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD1_k127_2687196_9 469383.Cwoe_4140 1.463e-12 72.0 COG2159@1|root,COG2159@2|Bacteria,2GZH0@201174|Actinobacteria 201174|Actinobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_2693958_1 1541065.JRFE01000048_gene3281 4.114e-08 58.0 2DP9S@1|root,3315I@2|Bacteria,1G9CH@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_2693958_2 215803.DB30_5946 0.0005669 51.0 COG0810@1|root,COG1716@1|root,COG0810@2|Bacteria,COG1716@2|Bacteria,1QX84@1224|Proteobacteria,430UC@68525|delta/epsilon subdivisions,2WVSU@28221|Deltaproteobacteria,2YYAP@29|Myxococcales 28221|Deltaproteobacteria MT Forkhead associated domain - - - - - - - - - - - - Yop-YscD_cpl DYD1_k127_2693958_0 443152.MDG893_15295 1.873e-52 199.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_2698928_0 370438.PTH_1335 4.019e-51 191.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,24AIH@186801|Clostridia,260C4@186807|Peptococcaceae 186801|Clostridia G Belongs to the HpcH HpaI aldolase family - - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI DYD1_k127_2698928_2 646529.Desaci_1636 1.351e-07 64.0 COG0477@1|root,COG2814@2|Bacteria,1V36U@1239|Firmicutes,2585F@186801|Clostridia,264YU@186807|Peptococcaceae 186801|Clostridia EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_2698928_1 323261.Noc_1568 3.155e-49 177.0 COG2337@1|root,COG2337@2|Bacteria,1RIPH@1224|Proteobacteria,1S7VW@1236|Gammaproteobacteria,1WYQY@135613|Chromatiales 135613|Chromatiales L Toxic component of a toxin-antitoxin (TA) module - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD1_k127_2699237_2 351160.RCIX322 2.315e-42 165.0 COG0428@1|root,arCOG00576@2157|Archaea,2XX28@28890|Euryarchaeota,2NAV5@224756|Methanomicrobia 224756|Methanomicrobia P divalent heavy-metal cations transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - - DYD1_k127_2699237_5 382464.ABSI01000016_gene745 6.406e-10 59.0 COG2259@1|root,COG2259@2|Bacteria,46T2M@74201|Verrucomicrobia,2IUPP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX DYD1_k127_2699237_4 234267.Acid_0142 4.33e-22 98.0 COG2259@1|root,COG2259@2|Bacteria,3Y4XF@57723|Acidobacteria 57723|Acidobacteria S TQO small subunit DoxD - - - ko:K15977 - - - - ko00000 - - - DoxX DYD1_k127_2699237_3 479431.Namu_2818 2.041e-27 113.0 COG0025@1|root,COG5207@1|root,COG0025@2|Bacteria,COG5207@2|Bacteria,2GIUT@201174|Actinobacteria,4ERRH@85013|Frankiales 201174|Actinobacteria P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger,zf-UBP DYD1_k127_2699237_6 1267535.KB906767_gene561 1.634e-08 57.0 COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia 204432|Acidobacteriia P SNARE associated Golgi protein - - - - - - - - - - - - Rhodanese,SNARE_assoc DYD1_k127_2699237_1 234267.Acid_1248 2.564e-83 284.0 COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria 57723|Acidobacteria P SNARE associated Golgi protein - - - - - - - - - - - - Rhodanese,SNARE_assoc DYD1_k127_2699237_0 1120960.ATXG01000005_gene2561 3.561e-86 301.0 COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria,4FR3H@85023|Microbacteriaceae 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_2726274_21 243231.GSU1496 9.787e-05 45.0 COG4968@1|root,COG4968@2|Bacteria,1QXNR@1224|Proteobacteria,43C4N@68525|delta/epsilon subdivisions,2WRDZ@28221|Deltaproteobacteria,43VE1@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Prokaryotic N-terminal methylation motif pilA-N - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin_PilA DYD1_k127_2726274_8 1499967.BAYZ01000027_gene1786 1.369e-97 344.0 COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria 2|Bacteria T Two component, sigma54 specific, transcriptional regulator, Fis family pilR - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_2726274_6 1232410.KI421416_gene2594 1.017e-144 469.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43RZ2@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Type II secretion system (T2SS), protein F pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF DYD1_k127_2726274_3 1125863.JAFN01000001_gene2904 1.584e-210 668.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU PFAM Type II secretion system protein E pilB - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N,cNMP_binding DYD1_k127_2726274_0 909663.KI867149_gene3375 0.0 1186.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MQB6@213462|Syntrophobacterales 28221|Deltaproteobacteria G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N DYD1_k127_2726274_17 56780.SYN_01535 2.555e-34 141.0 COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,2MQM5@213462|Syntrophobacterales 28221|Deltaproteobacteria L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N DYD1_k127_2726274_15 338966.Ppro_1405 1.348e-41 161.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,43UPB@69541|Desulfuromonadales 28221|Deltaproteobacteria J Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE DYD1_k127_2726274_2 1232410.KI421424_gene1722 1.211e-310 961.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,43TCM@69541|Desulfuromonadales 28221|Deltaproteobacteria O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD1_k127_2726274_5 1232410.KI421424_gene1723 1.366e-151 487.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales 28221|Deltaproteobacteria O DnaJ central domain dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD1_k127_2726274_1 338966.Ppro_2604 1.703e-320 1000.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,43T3K@69541|Desulfuromonadales 28221|Deltaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon-3 - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD1_k127_2726274_10 443143.GM18_3748 3.467e-65 238.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,43UHS@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD1_k127_2726274_9 443143.GM18_4083 6.669e-88 297.0 COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase - - - ko:K06898 - - - - ko00000 - - - AIRC DYD1_k127_2726274_18 247490.KSU1_C0335 1.594e-24 108.0 COG1371@1|root,COG1371@2|Bacteria,2J0RY@203682|Planctomycetes 203682|Planctomycetes S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease DYD1_k127_2726274_4 330214.NIDE3049 1.116e-171 550.0 COG1078@1|root,COG1078@2|Bacteria,3J0YB@40117|Nitrospirae 40117|Nitrospirae S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06885 - - - - ko00000 - - - HD DYD1_k127_2726274_13 56780.SYN_01980 6.844e-60 215.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,43ADJ@68525|delta/epsilon subdivisions,2WMPS@28221|Deltaproteobacteria,2MRRX@213462|Syntrophobacterales 28221|Deltaproteobacteria G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF987.Gmet_0920 SIS_2 DYD1_k127_2726274_7 330214.NIDE4314 1.373e-115 380.0 COG1899@1|root,COG1899@2|Bacteria 2|Bacteria O peptidyl-lysine modification to peptidyl-hypusine - - - - - - - - - - - - - DYD1_k127_2726274_11 1125863.JAFN01000001_gene666 1.269e-61 221.0 COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria 28221|Deltaproteobacteria S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans DYD1_k127_2726274_12 1519464.HY22_06960 1.011e-60 214.0 COG2131@1|root,COG2131@2|Bacteria,1FDBV@1090|Chlorobi 1090|Chlorobi F PFAM CMP dCMP deaminase zinc-binding - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 DYD1_k127_2726274_19 502025.Hoch_4471 4.545e-13 73.0 COG0636@1|root,COG0636@2|Bacteria,1QAIF@1224|Proteobacteria,43A8Y@68525|delta/epsilon subdivisions,2X9Z1@28221|Deltaproteobacteria,2YW38@29|Myxococcales 28221|Deltaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C DYD1_k127_2726274_14 1184267.A11Q_9 2.192e-46 177.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2MT1Y@213481|Bdellovibrionales,2WKX1@28221|Deltaproteobacteria 213481|Bdellovibrionales C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A DYD1_k127_2726274_20 1322246.BN4_12553 3.749e-05 51.0 COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42WTD@68525|delta/epsilon subdivisions,2WSRU@28221|Deltaproteobacteria,2MDF1@213115|Desulfovibrionales 28221|Deltaproteobacteria S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter atpZ - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 DYD1_k127_2726274_16 552811.Dehly_0457 1.296e-40 154.0 COG0001@1|root,COG0001@2|Bacteria 2|Bacteria H glutamate-1-semialdehyde 2,1-aminomutase activity hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS08395,iUMNK88_1353.UMNK88_158 Aminotran_3 DYD1_k127_2733231_0 1220534.B655_0941 1.129e-63 238.0 COG1032@1|root,arCOG01356@2157|Archaea 2157|Archaea C SMART Elongator protein 3 MiaB NifB - - 1.21.98.3 ko:K04034 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R06268,R06269,R06270 RC00741,RC01491,RC01492 ko00000,ko00001,ko01000 - - - B12-binding,Radical_SAM DYD1_k127_2733231_1 502025.Hoch_5030 3.074e-55 202.0 COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,42ZSX@68525|delta/epsilon subdivisions,2WV17@28221|Deltaproteobacteria,2YZ2N@29|Myxococcales 28221|Deltaproteobacteria IQ reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_2733231_2 1121468.AUBR01000047_gene1883 7.485e-25 116.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,42EX2@68295|Thermoanaerobacterales 186801|Clostridia C FAD linked oxidase glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 DYD1_k127_2738293_7 1122217.KB899584_gene88 1.576e-55 197.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4H2QR@909932|Negativicutes 909932|Negativicutes E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase DYD1_k127_2738293_3 56780.SYN_02161 4.017e-110 366.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MR4I@213462|Syntrophobacterales 28221|Deltaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD1_k127_2738293_4 944479.JQLX01000010_gene518 3.358e-84 287.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2M703@213113|Desulfurellales 28221|Deltaproteobacteria E Dihydrodipicolinate reductase, C-terminus dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N DYD1_k127_2738293_14 1121020.JIAG01000010_gene174 1.013e-14 79.0 COG1487@1|root,COG1487@2|Bacteria,2IR5C@201174|Actinobacteria 201174|Actinobacteria S PIN domain - - - - - - - - - - - - PIN DYD1_k127_2738293_2 632518.Calow_1188 6.616e-177 569.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b DYD1_k127_2738293_1 671143.DAMO_2495 1.947e-204 653.0 COG1132@1|root,COG1132@2|Bacteria,2NNN4@2323|unclassified Bacteria 2|Bacteria V ABC transporter transmembrane region mdlA - - ko:K06147,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_2738293_0 671143.DAMO_2494 9.189e-238 756.0 COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria 2|Bacteria V ABC transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_2738293_15 497964.CfE428DRAFT_6311 1.729e-07 57.0 299BV@1|root,2ZWES@2|Bacteria,46WNG@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - DYD1_k127_2738293_5 483219.LILAB_02305 9.994e-61 215.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2WQ2K@28221|Deltaproteobacteria,2YV8W@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx DYD1_k127_2738293_13 338966.Ppro_2206 2.45e-16 82.0 COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,43TZS@69541|Desulfuromonadales 28221|Deltaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 DYD1_k127_2738293_17 553973.CLOHYLEM_06996 7.653e-06 50.0 arCOG06833@1|root,33E0U@2|Bacteria,1VNIW@1239|Firmicutes,25E1N@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_2738293_18 879212.DespoDRAFT_03090 1.476e-05 52.0 COG1943@1|root,COG1943@2|Bacteria 2|Bacteria L Transposase - - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - - DYD1_k127_2738293_19 485913.Krac_10366 0.000877 44.0 COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria,2G6I4@200795|Chloroflexi 200795|Chloroflexi L PFAM helicase domain protein - - - - - - - - - - - - Helicase_C,PLDc_2,SNF2_N DYD1_k127_2738293_16 631362.Thi970DRAFT_02897 1.483e-06 52.0 COG1848@1|root,COG1848@2|Bacteria 2|Bacteria G Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN,PIN_3 DYD1_k127_2738293_8 1288079.AUKN01000003_gene3874 6.781e-41 158.0 COG1032@1|root,COG1032@2|Bacteria,2GZU1@201174|Actinobacteria 201174|Actinobacteria C radical SAM domain protein - - - - - - - - - - - - - DYD1_k127_2738293_9 105425.BBPL01000045_gene3219 1.293e-40 160.0 COG1032@1|root,COG1032@2|Bacteria,2GZU1@201174|Actinobacteria,2NI0T@228398|Streptacidiphilus 201174|Actinobacteria C radical SAM domain protein - - - - - - - - - - - - - DYD1_k127_2738293_11 163908.KB235896_gene2431 2.094e-28 128.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1HQEI@1161|Nostocales 1117|Cyanobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_2738293_6 671143.DAMO_2494 8.938e-60 211.0 COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria 2|Bacteria V ABC transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_2738293_12 113355.CM001775_gene2001 6.782e-27 114.0 COG4634@1|root,COG4634@2|Bacteria,1GA41@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_2738293_10 1173028.ANKO01000020_gene5476 5.473e-30 121.0 COG2442@1|root,COG2442@2|Bacteria,1G9FC@1117|Cyanobacteria,1HDDA@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 DYD1_k127_2751142_3 1463909.KL585951_gene2348 5.996e-43 168.0 COG0596@1|root,COG0596@2|Bacteria,2I411@201174|Actinobacteria 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_2751142_1 314230.DSM3645_08892 2.818e-100 343.0 COG2141@1|root,COG2141@2|Bacteria,2J00I@203682|Planctomycetes 203682|Planctomycetes C PFAM Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_2751142_2 880072.Desac_1175 3.939e-75 258.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales 28221|Deltaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD1_k127_2751142_0 330214.NIDE0843 1.646e-285 884.0 COG1032@1|root,COG1032@2|Bacteria,3J18Y@40117|Nitrospirae 40117|Nitrospirae C B12 binding domain - - - - - - - - - - - - B12-binding,Radical_SAM DYD1_k127_2751725_2 1380394.JADL01000021_gene1881 7.698e-75 255.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase DYD1_k127_2751725_4 469383.Cwoe_1854 5.003e-70 251.0 COG4034@1|root,COG4034@2|Bacteria 2|Bacteria F Protein of unknown function (DUF1152) - - - - - - - - - - - - DUF1152 DYD1_k127_2751725_3 1379698.RBG1_1C00001G0620 2.993e-71 256.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_2751725_5 1379698.RBG1_1C00001G0620 1.714e-69 251.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_2751725_8 1123371.ATXH01000001_gene1180 1.079e-30 126.0 2D7FD@1|root,32TNY@2|Bacteria,2GHX6@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Domain of unknown function (DUF1992) - - - - - - - - - - - - DUF1992 DYD1_k127_2751725_7 1205680.CAKO01000040_gene1081 4.854e-41 157.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase DYD1_k127_2751725_6 1120936.KB907220_gene1954 1.993e-45 179.0 COG1840@1|root,COG1840@2|Bacteria 2|Bacteria P iron ion homeostasis - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11,SBP_bac_6,SBP_bac_8 DYD1_k127_2751725_0 105422.BBPM01000113_gene3362 2.614e-127 427.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,2NKS5@228398|Streptacidiphilus 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_2751725_1 1042326.AZNV01000012_gene1946 3.379e-78 276.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,4B8NG@82115|Rhizobiaceae 28211|Alphaproteobacteria E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 DYD1_k127_2751725_9 477974.Daud_1720 1.602e-12 72.0 COG0778@1|root,COG0778@2|Bacteria,1V75Q@1239|Firmicutes,24J37@186801|Clostridia,266UG@186807|Peptococcaceae 186801|Clostridia C Nitroreductase family - - - - - - - - - - - - Nitroreductase DYD1_k127_2756624_5 392499.Swit_1136 8.32e-06 58.0 2DV9I@1|root,32UYX@2|Bacteria,1R63U@1224|Proteobacteria,2U39U@28211|Alphaproteobacteria,2KBNS@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_2756624_3 1280952.HJA_13655 1.035e-90 304.0 COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,2TTWH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MA20_24385 - - - - - - - - - - - adh_short DYD1_k127_2756624_0 1380394.JADL01000017_gene493 1.509e-157 508.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,2TSVE@28211|Alphaproteobacteria,2JQ2G@204441|Rhodospirillales 204441|Rhodospirillales C FAD binding domain - - 1.1.3.8 ko:K00103 ko00053,ko01100,map00053,map01100 M00129 R00647,R03184,R10053 RC00195,RC00346,RC00869 ko00000,ko00001,ko00002,ko01000 - - - ALO,FAD_binding_4 DYD1_k127_2756624_1 670292.JH26_26705 1.135e-122 409.0 COG0382@1|root,COG0560@1|root,COG0382@2|Bacteria,COG0560@2|Bacteria,1MXCM@1224|Proteobacteria,2TS0Z@28211|Alphaproteobacteria,1JQYX@119045|Methylobacteriaceae 28211|Alphaproteobacteria H PFAM UbiA prenyltransferase - - - - - - - - - - - - HAD,UbiA DYD1_k127_2756624_2 1502851.FG93_01907 1.532e-111 370.0 COG0451@1|root,COG0451@2|Bacteria,1MW3K@1224|Proteobacteria,2TTTJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM Epimerase dehydratase - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD1_k127_2756624_4 1547437.LL06_23350 1.002e-36 141.0 COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria,2UINX@28211|Alphaproteobacteria,43JZB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_2761122_13 1123023.JIAI01000001_gene6192 1.248e-05 50.0 COG4638@1|root,COG4638@2|Bacteria,2GP8J@201174|Actinobacteria 201174|Actinobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Aromatic_hydrox,Rieske DYD1_k127_2761122_12 1120949.KB903314_gene303 2.09e-21 107.0 COG1840@1|root,COG1840@2|Bacteria 2|Bacteria P iron ion homeostasis - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_2761122_2 1120949.KB903314_gene302 3.398e-127 426.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria 201174|Actinobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_2761122_7 1283283.ATXA01000006_gene1844 1.581e-73 262.0 COG3384@1|root,COG3384@2|Bacteria,2GJDG@201174|Actinobacteria 201174|Actinobacteria S PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - - - - - - - - - - LigB DYD1_k127_2761122_11 1231391.AMZF01000068_gene2179 1.28e-29 133.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_2761122_4 631454.N177_3820 3.98e-116 386.0 COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,1JQCV@119043|Rhodobiaceae 28211|Alphaproteobacteria S LVIVD repeat - - - - - - - - - - - - LVIVD DYD1_k127_2761122_1 105422.BBPM01000113_gene3362 1.352e-128 432.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,2NKS5@228398|Streptacidiphilus 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_2761122_5 1192868.CAIU01000020_gene2936 8.56e-82 284.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,43GWP@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 DYD1_k127_2761122_6 1123504.JQKD01000049_gene2989 3.161e-74 266.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VRUP@28216|Betaproteobacteria,4AJ7Z@80864|Comamonadaceae 28216|Betaproteobacteria P Rieske [2Fe-2S] domain - - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_2761122_9 105422.BBPM01000113_gene3361 3.556e-42 169.0 COG1840@1|root,COG1840@2|Bacteria 2|Bacteria P iron ion homeostasis - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11,SBP_bac_6,SBP_bac_8 DYD1_k127_2761122_10 56110.Oscil6304_5208 1.255e-35 150.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 1117|Cyanobacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_2761122_0 414996.IL38_11625 1.011e-129 426.0 COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,4084I@622450|Actinopolysporales 201174|Actinobacteria E Cobalamin-independent synthase, Catalytic domain metE2 - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_2761122_3 675635.Psed_2533 3.416e-117 390.0 COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,4E8PX@85010|Pseudonocardiales 201174|Actinobacteria E Methionine synthase - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - - DYD1_k127_2761122_8 306281.AJLK01000103_gene3372 5.869e-69 243.0 COG2159@1|root,COG2159@2|Bacteria,1GKMU@1117|Cyanobacteria,1JMEX@1189|Stigonemataceae 1117|Cyanobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_2764750_1 1267533.KB906737_gene1726 2.962e-116 375.0 COG1740@1|root,COG1740@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor hupS - 1.12.99.6 ko:K06282 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFe_hyd_SSU_C,Oxidored_q6 DYD1_k127_2764750_2 1123229.AUBC01000024_gene4560 9.294e-71 261.0 COG3300@1|root,COG4191@1|root,COG3300@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JR0R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Response regulator receiver - - - - - - - - - - - - HATPase_c,HisKA,MASE1,MHYT,PAS,PAS_4,PAS_9,Response_reg DYD1_k127_2764750_0 309801.trd_1877 0.0 1017.0 COG0374@1|root,COG0374@2|Bacteria,2GBT5@200795|Chloroflexi,27YUX@189775|Thermomicrobia 189775|Thermomicrobia C nickel-dependent hydrogenase large subunit - - 1.12.99.6 ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases DYD1_k127_2781512_0 797299.HALLA_02515 3.217e-121 399.0 COG4948@1|root,arCOG01168@2157|Archaea,2XUAS@28890|Euryarchaeota,23SVB@183963|Halobacteria 183963|Halobacteria M COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD1_k127_2781512_1 640081.Dsui_0649 6.371e-72 250.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,2KV20@206389|Rhodocyclales 206389|Rhodocyclales E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase DYD1_k127_2781512_2 1266925.JHVX01000007_gene2364 1.841e-62 221.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,371TB@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function, DUF484 - - - ko:K09921 - - - - ko00000 - - - DUF484 DYD1_k127_2787253_4 269799.Gmet_3260 3.034e-178 567.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,43U60@69541|Desulfuromonadales 28221|Deltaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt DYD1_k127_2787253_3 56780.SYN_00123 9.714e-183 585.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2MQZI@213462|Syntrophobacterales 28221|Deltaproteobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT DYD1_k127_2787253_8 1379858.N508_00615 2.004e-133 435.0 COG0075@1|root,COG0075@2|Bacteria,2GEIZ@200930|Deferribacteres 200930|Deferribacteres E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD1_k127_2787253_20 113395.AXAI01000005_gene3816 4.01e-61 223.0 COG0667@1|root,COG0667@2|Bacteria,1R5BH@1224|Proteobacteria,2TS0A@28211|Alphaproteobacteria,3JU90@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD1_k127_2787253_17 443152.MDG893_15050 2.88e-82 287.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,1RR4Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Cyclodeaminase ocd2 - 1.4.1.1,4.3.1.12 ko:K01750,ko:K19244 ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230 - R00396,R00671 RC00008,RC00354 ko00000,ko00001,ko01000 - - iJN746.PP_4431 OCD_Mu_crystall DYD1_k127_2787253_31 1305836.AXVE01000003_gene2232 1.185e-15 83.0 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli,26D6N@186818|Planococcaceae 91061|Bacilli S Acetoin utilization protein acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS DYD1_k127_2787253_33 1255043.TVNIR_1335 1.683e-10 65.0 COG1872@1|root,COG1872@2|Bacteria 2|Bacteria I DUF167 CP_0257 - - ko:K09131 - - - - ko00000 - - - DUF167 DYD1_k127_2787253_23 1134413.ANNK01000087_gene240 1.168e-47 186.0 COG2223@1|root,COG2223@2|Bacteria,1UJI3@1239|Firmicutes,4IT9X@91061|Bacilli,1ZSAX@1386|Bacillus 91061|Bacilli P MFS_1 like family - - - - - - - - - - - - MFS_1 DYD1_k127_2787253_14 933262.AXAM01000066_gene1688 1.743e-91 318.0 COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2MI1U@213118|Desulfobacterales 28221|Deltaproteobacteria M PFAM peptidase - - - - - - - - - - - - Peptidase_M23 DYD1_k127_2787253_18 1232410.KI421422_gene2079 2.096e-80 276.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,43S4Z@69541|Desulfuromonadales 28221|Deltaproteobacteria L RadC-like JAB domain radC - - ko:K03630 - - - - ko00000 - - - RadC DYD1_k127_2787253_11 309801.trd_1791 5.298e-115 383.0 COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi 200795|Chloroflexi J SMART PUA domain containing protein - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM DYD1_k127_2787253_21 1232410.KI421412_gene158 1.115e-58 207.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2WP2P@28221|Deltaproteobacteria,43SIN@69541|Desulfuromonadales 28221|Deltaproteobacteria H MoaC family moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC DYD1_k127_2787253_9 525904.Tter_1226 4.47e-123 404.0 COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria 2|Bacteria O Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 - - iNJ661.Rv3913 Pyr_redox_2 DYD1_k127_2787253_32 1300345.LF41_2234 1.385e-15 83.0 2CKE6@1|root,32ZEV@2|Bacteria,1NBRM@1224|Proteobacteria,1SCY3@1236|Gammaproteobacteria,1X8E5@135614|Xanthomonadales 135614|Xanthomonadales S Family of unknown function (DUF5329) - - - - - - - - - - - - DUF5329 DYD1_k127_2787253_22 1231391.AMZF01000020_gene1927 1.318e-57 207.0 COG1335@1|root,COG1335@2|Bacteria 2|Bacteria Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides yecD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Isochorismatase DYD1_k127_2787253_5 204669.Acid345_1270 7.675e-155 505.0 COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia 204432|Acidobacteriia Q Flavin containing amine oxidoreductase - - - - - - - - - - - - NAD_binding_8 DYD1_k127_2787253_0 204669.Acid345_1270 5.319e-255 796.0 COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia 204432|Acidobacteriia Q Flavin containing amine oxidoreductase - - - - - - - - - - - - NAD_binding_8 DYD1_k127_2787253_7 204669.Acid345_1269 3.241e-134 439.0 COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria,2JI8G@204432|Acidobacteriia 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C DYD1_k127_2787253_12 653733.Selin_1955 1.872e-113 370.0 COG0107@1|root,COG0107@2|Bacteria 2|Bacteria E imidazoleglycerol-phosphate synthase activity hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD1_k127_2787253_27 338963.Pcar_2974 2.155e-33 137.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM OmpA MotB domain protein pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD1_k127_2787253_30 1089553.Tph_c05410 4.84e-26 121.0 COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,42EWT@68295|Thermoanaerobacterales 186801|Clostridia T Signal transduction histidine kinase degS - 2.7.13.3 ko:K07777 ko02020,map02020 M00478 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DegS,HATPase_c,HisKA_3 DYD1_k127_2787253_25 203119.Cthe_1267 7.136e-46 174.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,3WHYU@541000|Ruminococcaceae 186801|Clostridia K PFAM response regulator receiver degU - - - - - - - - - - - GerE,Response_reg DYD1_k127_2787253_28 398767.Glov_3208 1.479e-30 125.0 COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,42TPK@68525|delta/epsilon subdivisions 1224|Proteobacteria T PFAM zinc finger, DksA TraR C4-type dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR DYD1_k127_2787253_6 338966.Ppro_3094 1.884e-145 474.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,43TZ3@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 DYD1_k127_2787253_29 1499967.BAYZ01000158_gene441 5.137e-28 123.0 COG2834@1|root,COG2834@2|Bacteria,2NQ6V@2323|unclassified Bacteria 2|Bacteria M Outer membrane lipoprotein carrier protein LolA lolA - - ko:K03634 - - - - ko00000 - - - LolA DYD1_k127_2787253_2 243231.GSU3112 1.917e-207 668.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,43UK2@69541|Desulfuromonadales 28221|Deltaproteobacteria D PFAM cell divisionFtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma DYD1_k127_2787253_1 269799.Gmet_0366 2.309e-209 665.0 COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,43U97@69541|Desulfuromonadales 28221|Deltaproteobacteria J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnj - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2,RMMBL DYD1_k127_2787253_26 96561.Dole_0983 1.222e-45 175.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MJG9@213118|Desulfobacterales 28221|Deltaproteobacteria I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_2787253_24 667014.Thein_1686 2.289e-46 171.0 COG0629@1|root,COG0629@2|Bacteria,2GHSS@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB DYD1_k127_2787253_16 1226994.AMZB01000120_gene3399 1.747e-84 294.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1YE6Q@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family hprA - 1.1.1.29 ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 M00346 R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_2787253_19 1121428.DESHY_40177___1 6.108e-75 260.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,2613S@186807|Peptococcaceae 186801|Clostridia S TIGRFAM MazG family protein mazG - 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase DYD1_k127_2787253_13 1122604.JONR01000001_gene1775 5.19e-92 313.0 COG0596@1|root,COG0596@2|Bacteria,1NDHC@1224|Proteobacteria,1SM95@1236|Gammaproteobacteria 1236|Gammaproteobacteria S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_2787253_10 357808.RoseRS_2741 3.488e-122 399.0 COG0388@1|root,COG0388@2|Bacteria,2G6KM@200795|Chloroflexi,375XY@32061|Chloroflexia 32061|Chloroflexia S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase DYD1_k127_2787253_15 357808.RoseRS_2742 3.246e-89 302.0 COG2957@1|root,COG2957@2|Bacteria,2GAHD@200795|Chloroflexi,37657@32061|Chloroflexia 32061|Chloroflexia E Belongs to the agmatine deiminase family - - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph DYD1_k127_2793728_5 489825.LYNGBM3L_33200 2.184e-23 102.0 COG3514@1|root,COG3514@2|Bacteria,1GA67@1117|Cyanobacteria,1HHPB@1150|Oscillatoriales 1117|Cyanobacteria S BrnA antitoxin of type II toxin-antitoxin system - - - - - - - - - - - - BrnA_antitoxin DYD1_k127_2793728_9 1300345.LF41_1584 6.709e-07 55.0 COG2929@1|root,COG2929@2|Bacteria,1NG9V@1224|Proteobacteria,1SGBF@1236|Gammaproteobacteria,1X8WM@135614|Xanthomonadales 135614|Xanthomonadales S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - ko:K09803 - - - - ko00000 - - - BrnT_toxin DYD1_k127_2793728_3 1565314.OA34_09575 7.244e-54 196.0 2BA14@1|root,323EW@2|Bacteria,1P0WT@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_2793728_8 573370.DMR_04550 6.347e-12 68.0 COG1598@1|root,COG1598@2|Bacteria,1RIRX@1224|Proteobacteria,42W3D@68525|delta/epsilon subdivisions,2WRPE@28221|Deltaproteobacteria,2MC8P@213115|Desulfovibrionales 28221|Deltaproteobacteria S HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox DYD1_k127_2793728_7 272123.Anacy_2755 1.229e-14 75.0 COG1724@1|root,COG1724@2|Bacteria,1GI62@1117|Cyanobacteria,1HT1T@1161|Nostocales 1117|Cyanobacteria N Periplasmic or secreted lipoprotein - - - - - - - - - - - - HicA_toxin DYD1_k127_2793728_6 1487953.JMKF01000026_gene1431 2.766e-21 96.0 2EDMC@1|root,337H6@2|Bacteria,1G9TT@1117|Cyanobacteria,1HGDC@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_2793728_4 1487953.JMKF01000026_gene1430 1.681e-47 173.0 COG1569@1|root,COG1569@2|Bacteria,1GBGT@1117|Cyanobacteria,1HEPG@1150|Oscillatoriales 1117|Cyanobacteria S PIN domain - - - - - - - - - - - - PIN DYD1_k127_2793728_1 1380394.JADL01000004_gene5718 4.921e-105 354.0 COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TT8C@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_2793728_2 261292.Nit79A3_1620 1.532e-95 320.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2VPHG@28216|Betaproteobacteria,372X8@32003|Nitrosomonadales 28216|Betaproteobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase DYD1_k127_2793728_0 118173.KB235914_gene1926 1.535e-106 355.0 COG0500@1|root,COG2226@2|Bacteria,1G0WT@1117|Cyanobacteria,1HC1U@1150|Oscillatoriales 1117|Cyanobacteria Q Dimerisation domain - - - - - - - - - - - - Dimerisation2,Methyltransf_2 DYD1_k127_2795387_6 1123371.ATXH01000016_gene1824 3.099e-16 80.0 COG1910@1|root,COG1910@2|Bacteria,2GIB4@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_17,PBP_like DYD1_k127_2795387_0 671143.DAMO_1132 3.898e-102 339.0 COG2998@1|root,COG2998@2|Bacteria,2NP4U@2323|unclassified Bacteria 2|Bacteria H PBP superfamily domain tupB - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 DYD1_k127_2795387_2 671143.DAMO_1144 3.683e-95 317.0 COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria 2|Bacteria H Binding-protein-dependent transport system inner membrane component tupB - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 DYD1_k127_2795387_3 671143.DAMO_1145 3.43e-75 261.0 COG3842@1|root,COG3842@2|Bacteria,2NNPE@2323|unclassified Bacteria 2|Bacteria E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system gtsA - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 ko:K02010,ko:K02045,ko:K02049,ko:K02068,ko:K02071,ko:K06857,ko:K10112,ko:K11072 ko00920,ko02010,map00920,map02010 M00185,M00186,M00188,M00190,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00211,M00238,M00299,M00491,M00602,M00605,M00606 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.10,3.A.1.11.1,3.A.1.16,3.A.1.17,3.A.1.24,3.A.1.6.1,3.A.1.6.2,3.A.1.6.3,3.A.1.6.4 - - ABC_tran,TOBE_2 DYD1_k127_2795387_5 1192034.CAP_3490 3.963e-30 123.0 29EH1@1|root,336FM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2795387_4 479434.Sthe_3392 1.853e-60 221.0 COG3058@1|root,COG3058@2|Bacteria,2G9S5@200795|Chloroflexi,27YFM@189775|Thermomicrobia 189775|Thermomicrobia O Protein involved in formate dehydrogenase formation - - - ko:K02380 - - - - ko00000 - - - FdhE DYD1_k127_2795387_1 479434.Sthe_3390 3.831e-98 328.0 COG3301@1|root,COG3301@2|Bacteria,2GA0G@200795|Chloroflexi,27YBQ@189775|Thermomicrobia 189775|Thermomicrobia P Polysulphide reductase, NrfD - - - - - - - - - - - - NrfD DYD1_k127_2829691_0 671143.DAMO_0383 1.066e-63 230.0 COG1801@1|root,COG1801@2|Bacteria,2NPDU@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 DYD1_k127_2865233_4 502025.Hoch_6851 2.038e-09 59.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2X9B9@28221|Deltaproteobacteria,2YX2A@29|Myxococcales 28221|Deltaproteobacteria P POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 DYD1_k127_2865233_5 1304880.JAGB01000001_gene423 2.609e-09 59.0 COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia 186801|Clostridia G Glycosyltransferase 36 associated ndvB - - - - - - - - - - - DUF3131,Glyco_hydro_36,Glyco_transf_36,Glycoamylase DYD1_k127_2865233_7 1379698.RBG1_1C00001G1799 5.365e-08 56.0 COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria 2|Bacteria S VIT family - - - - - - - - - - - - VIT1 DYD1_k127_2865233_2 317936.Nos7107_3521 1.291e-54 194.0 2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HS5Z@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_2865233_0 671143.DAMO_0975 6.066e-250 789.0 COG0465@1|root,COG0465@2|Bacteria,2NP22@2323|unclassified Bacteria 2|Bacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD1_k127_2865233_6 861299.J421_3379 8.6e-09 61.0 COG3809@1|root,COG3809@2|Bacteria 2|Bacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - Rhomboid,zf-TFIIB DYD1_k127_2865233_1 243231.GSU2430 4.88e-91 305.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,43S6P@69541|Desulfuromonadales 28221|Deltaproteobacteria O prohibitin homologues - - - - - - - - - - - - Band_7 DYD1_k127_2865233_3 443144.GM21_0541 7.741e-11 65.0 28T91@1|root,2ZFHN@2|Bacteria,1P659@1224|Proteobacteria,433I9@68525|delta/epsilon subdivisions,2WX6G@28221|Deltaproteobacteria,43VY2@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_2918102_0 1396418.BATQ01000050_gene289 0.0 1106.0 COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,46SI7@74201|Verrucomicrobia,2IV43@203494|Verrucomicrobiae 203494|Verrucomicrobiae T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Response_reg DYD1_k127_2918102_5 1123261.AXDW01000022_gene232 2.632e-51 193.0 COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,1S0NE@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD1_k127_2918102_6 1196323.ALKF01000202_gene3929 1.925e-31 137.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,4HIMD@91061|Bacilli,26TDP@186822|Paenibacillaceae 91061|Bacilli T CHASE2 - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc DYD1_k127_2918102_2 748247.AZKH_0539 3.267e-92 310.0 COG5486@1|root,COG5486@2|Bacteria,1R6FN@1224|Proteobacteria,2VMCU@28216|Betaproteobacteria 28216|Betaproteobacteria S Predicted metal-binding integral membrane protein (DUF2182) - - - - - - - - - - - - DUF2182 DYD1_k127_2918102_3 1071679.BG57_07675 6.917e-80 271.0 COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2VMAI@28216|Betaproteobacteria,1JZMB@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 DYD1_k127_2918102_8 48698.ENSPFOP00000018228 2.351e-09 71.0 28INT@1|root,2QRN2@2759|Eukaryota,39NNU@33154|Opisthokonta,3CQ7A@33208|Metazoa,3E6C9@33213|Bilateria,48RTH@7711|Chordata,49N70@7742|Vertebrata,49UUJ@7898|Actinopterygii 33208|Metazoa S Si ch211-220f16.2 - - - ko:K20478 - - - - ko00000,ko04131 - - - - DYD1_k127_2918102_1 868595.Desca_0602 5.818e-115 387.0 COG0849@1|root,COG0849@2|Bacteria,1TQC5@1239|Firmicutes,24BFJ@186801|Clostridia,2605E@186807|Peptococcaceae 186801|Clostridia D TIGRFAM conserved mutL2 - - - - - - - - - - - MutL DYD1_k127_2918102_7 1041139.KB902646_gene3338 4.215e-11 74.0 COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,4BBDJ@82115|Rhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_2918102_4 767817.Desgi_0645 1.704e-77 274.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,2607C@186807|Peptococcaceae 186801|Clostridia C PFAM CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_2921413_4 234267.Acid_0123 9.978e-16 77.0 COG2096@1|root,COG2096@2|Bacteria,3Y77H@57723|Acidobacteria 57723|Acidobacteria S Cobalamin adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans DYD1_k127_2921413_1 1047013.AQSP01000037_gene1322 1.455e-111 376.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - ko:K03294,ko:K13868 ko04974,map04974 - - - ko00000,ko00001,ko02000 2.A.3.2,2.A.3.8.15 - - AA_permease_2 DYD1_k127_2921413_5 351627.Csac_0217 4.447e-11 69.0 COG2250@1|root,COG2250@2|Bacteria,1VA9W@1239|Firmicutes,24KUA@186801|Clostridia,42IHX@68295|Thermoanaerobacterales 186801|Clostridia S Higher Eukarytoes and Prokaryotes Nucleotide-binding domain - - - - - - - - - - - - HEPN DYD1_k127_2921413_3 926550.CLDAP_25980 1.576e-26 112.0 COG1708@1|root,COG1708@2|Bacteria,2G8N6@200795|Chloroflexi 200795|Chloroflexi S Nucleotidyltransferase domain - - - - - - - - - - - - NTP_transf_2 DYD1_k127_2921413_0 485913.Krac_0086 0.0 1221.0 COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria 2|Bacteria V DNA modification - - - - - - - - - - - - Eco57I,HSDR_N,N6_Mtase,TaqI_C DYD1_k127_2921413_2 189753.AXAS01000041_gene2534 7.116e-77 269.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_2924244_5 711393.AYRX01000077_gene579 3.043e-09 64.0 COG2905@1|root,COG2905@2|Bacteria,2IJJ6@201174|Actinobacteria 201174|Actinobacteria T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD1_k127_2924244_1 443143.GM18_4143 1.65e-86 306.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,43U19@69541|Desulfuromonadales 28221|Deltaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_2924244_0 880073.Calab_3404 2.318e-139 456.0 COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria 2|Bacteria T Two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02667,ko:K07714 ko02020,map02020 M00500,M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_2924244_2 880072.Desac_0444 9.63e-57 214.0 COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42NE2@68525|delta/epsilon subdivisions 1224|Proteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 DYD1_k127_2924244_3 1415775.U729_3154 9.487e-17 93.0 COG1467@1|root,COG1467@2|Bacteria,1VHYM@1239|Firmicutes 1239|Firmicutes L DNA primase activity - - - - - - - - - - - - PriCT_1 DYD1_k127_2924244_4 472759.Nhal_0792 3.635e-11 64.0 COG2823@1|root,COG2823@2|Bacteria,1RFX5@1224|Proteobacteria,1SB3H@1236|Gammaproteobacteria,1X1GY@135613|Chromatiales 135613|Chromatiales S BON domain - - - - - - - - - - - - BON DYD1_k127_2926625_1 765420.OSCT_1132 9.598e-117 382.0 COG2141@1|root,COG2141@2|Bacteria,2GB4X@200795|Chloroflexi,3779M@32061|Chloroflexia 32061|Chloroflexia C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_2926625_0 886293.Sinac_3644 1.337e-135 440.0 COG3673@1|root,COG3673@2|Bacteria,2J3YE@203682|Planctomycetes 203682|Planctomycetes S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235 DYD1_k127_2926625_3 1385512.N784_08625 1.83e-13 77.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,2YA8W@289201|Pontibacillus 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 DYD1_k127_2926625_2 1487953.JMKF01000078_gene4088 2.252e-99 331.0 COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1H8JK@1150|Oscillatoriales 1117|Cyanobacteria O PDZ domain (Also known as DHR or GLGF) - - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 DYD1_k127_2934438_2 640081.Dsui_0871 1.94e-09 61.0 COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,2KX05@206389|Rhodocyclales 206389|Rhodocyclales S Bacterial protein of unknown function (DUF883) - - - - - - - - - - - - DUF883 DYD1_k127_2934438_0 105559.Nwat_1493 1.694e-87 304.0 COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales 135613|Chromatiales K ribonuclease BN - - - ko:K07058 - - - - ko00000 - - - Rrf2,Virul_fac_BrkB DYD1_k127_2934438_1 525904.Tter_0372 1.309e-40 154.0 COG0071@1|root,COG0071@2|Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_2942289_0 986075.CathTA2_1322 1.17e-123 409.0 COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,4HE36@91061|Bacilli 91061|Bacilli G C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM DYD1_k127_2942289_3 1034347.CAHJ01000012_gene2349 2.575e-25 111.0 COG4665@1|root,COG4665@2|Bacteria,1VECG@1239|Firmicutes,4HMM4@91061|Bacilli,1ZHPD@1386|Bacillus 91061|Bacilli Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD1_k127_2942289_2 398511.BpOF4_12530 1.187e-69 248.0 COG1638@1|root,COG1638@2|Bacteria,1UY2X@1239|Firmicutes,4HCVD@91061|Bacilli,1ZFCD@1386|Bacillus 91061|Bacilli G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP DYD1_k127_2942289_1 2074.JNYD01000002_gene5635 1.942e-94 318.0 COG0715@1|root,COG0715@2|Bacteria,2IEVS@201174|Actinobacteria,4E6SW@85010|Pseudonocardiales 201174|Actinobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - SBP_bac_3 DYD1_k127_2945314_6 323261.Noc_2765 5.43e-12 74.0 COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1R3SH@1224|Proteobacteria,1S6CN@1236|Gammaproteobacteria,1WYE5@135613|Chromatiales 135613|Chromatiales O Tetratricopeptide repeat - - - - - - - - - - - - TPR_12,TPR_7 DYD1_k127_2945314_0 331678.Cphamn1_1534 4.213e-55 201.0 COG0221@1|root,COG0221@2|Bacteria 2|Bacteria C inorganic diphosphatase activity - - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - ParBc_2,Pyrophosphatase DYD1_k127_2945314_4 331678.Cphamn1_1331 8.594e-26 123.0 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - CARDB DYD1_k127_2945314_5 1536774.H70357_07650 2.454e-18 99.0 COG0613@1|root,COG0613@2|Bacteria,1V2U3@1239|Firmicutes,4HF4C@91061|Bacilli,26WDG@186822|Paenibacillaceae 91061|Bacilli S DNA polymerase alpha chain like domain - - - - - - - - - - - - PHP DYD1_k127_2945314_9 1202768.JROF01000022_gene3290 8.146e-06 58.0 arCOG10745@1|root,arCOG10745@2157|Archaea 2157|Archaea C molybdopterin cofactor binding - - - - - - - - - - - - - DYD1_k127_2945314_7 909663.KI867149_gene3270 2.418e-10 72.0 COG4733@1|root,COG4733@2|Bacteria,1NPTD@1224|Proteobacteria,42Y31@68525|delta/epsilon subdivisions,2WSU6@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - - DYD1_k127_2945314_1 1396141.BATP01000003_gene5168 1.453e-37 154.0 2EKQJ@1|root,33EEC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2945314_3 1340493.JNIF01000003_gene2055 7.891e-30 124.0 COG3415@1|root,COG3415@2|Bacteria 2|Bacteria L Transposase - - - ko:K07499 - - - - ko00000 - - - HTH_23,HTH_29,HTH_32,HTH_33 DYD1_k127_2945314_2 1123508.JH636456_gene119 2.838e-37 146.0 COG3335@1|root,COG3335@2|Bacteria,2J1BU@203682|Planctomycetes 203682|Planctomycetes L DDE superfamily endonuclease - - - - - - - - - - - - DDE_3 DYD1_k127_2945314_8 589865.DaAHT2_2280 4.14e-07 58.0 COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria,42X6W@68525|delta/epsilon subdivisions,2WSY4@28221|Deltaproteobacteria,2MMCT@213118|Desulfobacterales 28221|Deltaproteobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K02458,ko:K02671 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15 - - N_methyl DYD1_k127_294882_2 1278073.MYSTI_05699 7.215e-194 625.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales 28221|Deltaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_294882_6 1449126.JQKL01000017_gene2765 2.032e-100 350.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,2687X@186813|unclassified Clostridiales 186801|Clostridia L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 DYD1_k127_294882_19 1232410.KI421412_gene100 1.357e-17 89.0 COG1286@1|root,COG1286@2|Bacteria,1NIBK@1224|Proteobacteria,42UFS@68525|delta/epsilon subdivisions,2WQIK@28221|Deltaproteobacteria,43SMV@69541|Desulfuromonadales 28221|Deltaproteobacteria S Colicin V production protein - - - ko:K03558 - - - - ko00000 - - - Colicin_V DYD1_k127_294882_16 443143.GM18_4146 4.711e-33 136.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,42SH8@68525|delta/epsilon subdivisions,2WQ3S@28221|Deltaproteobacteria,43UZW@69541|Desulfuromonadales 28221|Deltaproteobacteria S Yqey-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY DYD1_k127_294882_18 404589.Anae109_0759 3.349e-22 96.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 DYD1_k127_294882_13 1540257.JQMW01000013_gene1210 3.771e-49 185.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,36F9I@31979|Clostridiaceae 186801|Clostridia C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD DYD1_k127_294882_9 1499967.BAYZ01000118_gene3247 2.976e-82 281.0 COG1189@1|root,COG1189@2|Bacteria,2NPHR@2323|unclassified Bacteria 2|Bacteria J FtsJ-like methyltransferase tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 DYD1_k127_294882_1 696369.KI912183_gene1399 2.426e-229 727.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,2604R@186807|Peptococcaceae 186801|Clostridia H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C DYD1_k127_294882_8 243231.GSU1765 8.698e-89 302.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43UK9@69541|Desulfuromonadales 28221|Deltaproteobacteria H Polyprenyl synthetase ispA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt DYD1_k127_294882_20 443143.GM18_1114 8.097e-13 73.0 COG1722@1|root,COG1722@2|Bacteria,1Q1MM@1224|Proteobacteria,42X37@68525|delta/epsilon subdivisions,2WSNI@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S DYD1_k127_294882_14 667014.Thein_1537 5.004e-47 183.0 COG0739@1|root,COG0739@2|Bacteria,2GIB0@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD1_k127_294882_5 1232410.KI421421_gene3664 1.073e-115 386.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,43SB0@69541|Desulfuromonadales 28221|Deltaproteobacteria L OB-fold nucleic acid binding domain xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 DYD1_k127_294882_4 243231.GSU1772 1.688e-151 494.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,43TEQ@69541|Desulfuromonadales 28221|Deltaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 DYD1_k127_294882_12 243231.GSU1773 6.467e-53 204.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,43SYX@69541|Desulfuromonadales 28221|Deltaproteobacteria D Peptidase family M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23,SH3_3 DYD1_k127_294882_15 243231.GSU1774 1.363e-43 172.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria,43T0S@69541|Desulfuromonadales 28221|Deltaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX DYD1_k127_294882_10 1499967.BAYZ01000073_gene2043 4.165e-67 237.0 COG2884@1|root,COG2884@2|Bacteria,2NP95@2323|unclassified Bacteria 2|Bacteria D ATPases associated with a variety of cellular activities ftsE GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - ko:K09811,ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran DYD1_k127_294882_0 671143.DAMO_2996 0.0 1011.0 COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria 2|Bacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM DYD1_k127_294882_11 204669.Acid345_1339 1.525e-62 225.0 COG2912@1|root,COG2912@2|Bacteria,3Y53Z@57723|Acidobacteria,2JMYF@204432|Acidobacteriia 204432|Acidobacteriia S Transglutaminase-like superfamily - - - - - - - - - - - - TPR_9,Transglut_core2 DYD1_k127_294882_3 1231391.AMZF01000094_gene122 4.189e-182 587.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_294882_17 45130.XP_007698683.1 2.959e-25 117.0 2CXHA@1|root,2RXGX@2759|Eukaryota,38DQZ@33154|Opisthokonta,3P12I@4751|Fungi,3QQ9J@4890|Ascomycota,201P1@147541|Dothideomycetes 4751|Fungi S Domain of unknown function (DUF1932) - - - - - - - - - - - - DUF1932,F420_oxidored,NAD_binding_2 DYD1_k127_294882_7 118005.AWNK01000006_gene1372 4.969e-99 333.0 COG1611@1|root,COG1611@2|Bacteria 2|Bacteria S cytokinin biosynthetic process fas6 - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD1_k127_2952046_12 477974.Daud_1340 4.393e-111 366.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,26072@186807|Peptococcaceae 186801|Clostridia H PFAM Aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_2952046_9 338963.Pcar_0001 2.717e-154 499.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,43RXU@69541|Desulfuromonadales 28221|Deltaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N DYD1_k127_2952046_13 269799.Gmet_0002 1.295e-103 348.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,43T1D@69541|Desulfuromonadales 28221|Deltaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 DYD1_k127_2952046_14 1459636.NTE_01742 5.738e-87 296.0 COG2513@1|root,arCOG00581@2157|Archaea,41SEN@651137|Thaumarchaeota 651137|Thaumarchaeota G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase DYD1_k127_2952046_19 266117.Rxyl_3013 7.291e-61 218.0 COG1028@1|root,COG1028@2|Bacteria 266117.Rxyl_3013|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - DYD1_k127_2952046_11 1500257.JQNM01000014_gene2912 2.338e-132 428.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,4BCDD@82115|Rhizobiaceae 28211|Alphaproteobacteria P 4,5-dihydroxyphthalate decarboxylase - - - - - - - - - - - - NMT1 DYD1_k127_2952046_36 59374.Fisuc_1084 1.386e-15 88.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_2952046_20 1231391.AMZF01000029_gene212 5.732e-58 209.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VKYY@28216|Betaproteobacteria,3T2CN@506|Alcaligenaceae 28216|Betaproteobacteria G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II DYD1_k127_2952046_2 1382306.JNIM01000001_gene3484 2.588e-202 642.0 COG0365@1|root,COG0365@2|Bacteria 2|Bacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA badA - 6.2.1.25,6.2.1.27 ko:K04105,ko:K04110 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R01300,R01422 RC00004,RC00174 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C DYD1_k127_2952046_5 266117.Rxyl_1760 3.863e-170 547.0 COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CRW6@84995|Rubrobacteria 84995|Rubrobacteria C Aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_2952046_21 1268068.PG5_42060 2.251e-44 172.0 COG0726@1|root,COG3195@1|root,COG0726@2|Bacteria,COG3195@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria 1236|Gammaproteobacteria G deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 DYD1_k127_2952046_29 1246474.ANBE01000014_gene2905 3.41e-22 108.0 COG0119@1|root,COG0119@2|Bacteria,2INFJ@201174|Actinobacteria,4EMCZ@85012|Streptosporangiales 201174|Actinobacteria E HMGL-like - - 2.3.3.14 ko:K02594 ko00620,map00620 - R00271 RC00004,RC00067,RC02754 ko00000,ko00001,ko01000 - - - HMGL-like DYD1_k127_2952046_17 861299.J421_0778 2.592e-64 226.0 COG0225@1|root,COG0225@2|Bacteria,1ZUAQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR DYD1_k127_2952046_24 477974.Daud_2168 7.137e-31 128.0 COG1863@1|root,COG1863@2|Bacteria 2|Bacteria P multisubunit Na H antiporter MnhE subunit - - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE DYD1_k127_2952046_33 690850.Desaf_3628 1.629e-18 91.0 COG2212@1|root,COG2212@2|Bacteria,1N2PU@1224|Proteobacteria,42UDZ@68525|delta/epsilon subdivisions,2WQ3R@28221|Deltaproteobacteria,2MCJY@213115|Desulfovibrionales 28221|Deltaproteobacteria P PFAM multiple resistance and pH regulation protein F - - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MrpF_PhaF DYD1_k127_2952046_28 477974.Daud_2166 3.131e-24 105.0 COG1320@1|root,COG1320@2|Bacteria,1V93F@1239|Firmicutes,25I9V@186801|Clostridia,266FM@186807|Peptococcaceae 186801|Clostridia P PFAM Na H antiporter subunit - - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB DYD1_k127_2952046_35 1232410.KI421424_gene1709 6.732e-16 80.0 COG1563@1|root,COG1563@2|Bacteria,1N5EN@1224|Proteobacteria,42UDW@68525|delta/epsilon subdivisions,2WQK2@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Domain of unknown function (DUF4040) - - - - - - - - - - - - DUF4040 DYD1_k127_2952046_32 1469245.JFBG01000065_gene119 7.736e-19 92.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Na H antiporter, MnhB - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB DYD1_k127_2952046_23 1121413.JMKT01000008_gene1528 5.759e-38 152.0 COG2111@1|root,COG2111@2|Bacteria,1QI9J@1224|Proteobacteria,42UJ7@68525|delta/epsilon subdivisions,2WR3F@28221|Deltaproteobacteria,2MFXV@213115|Desulfovibrionales 28221|Deltaproteobacteria P PFAM Na H antiporter MnhB subunit-related protein - - - - - - - - - - - - MnhB DYD1_k127_2952046_25 1121448.DGI_2848 2.696e-29 120.0 COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria,42SX0@68525|delta/epsilon subdivisions,2WP3K@28221|Deltaproteobacteria,2MC72@213115|Desulfovibrionales 28221|Deltaproteobacteria P PFAM NADH-ubiquinone oxidoreductase chain 4L mnhC - - ko:K05567 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Oxidored_q2 DYD1_k127_2952046_10 1121413.JMKT01000008_gene1526 3.761e-151 492.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,42PD3@68525|delta/epsilon subdivisions,2WJ58@28221|Deltaproteobacteria,2MATX@213115|Desulfovibrionales 28221|Deltaproteobacteria CP PFAM NADH Ubiquinone plastoquinone (complex I) - - - ko:K05561,ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M DYD1_k127_2952046_6 1125863.JAFN01000001_gene2556 2.789e-168 543.0 COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,42MDX@68525|delta/epsilon subdivisions,2WJ56@28221|Deltaproteobacteria 28221|Deltaproteobacteria CP PFAM NADH Ubiquinone plastoquinone (complex I) - - - - - - - - - - - - Proton_antipo_M DYD1_k127_2952046_39 1262914.BN533_00573 4.552e-05 50.0 2DTCZ@1|root,33JS9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_2952046_3 1125863.JAFN01000001_gene2554 1.356e-178 578.0 COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,42MSA@68525|delta/epsilon subdivisions,2WIS1@28221|Deltaproteobacteria 28221|Deltaproteobacteria CP PFAM NADH Ubiquinone plastoquinone (complex I) - - - ko:K05568,ko:K12137 - - - - ko00000,ko01000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M DYD1_k127_2952046_16 656024.FsymDg_0185 2.485e-68 237.0 COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4ESIC@85013|Frankiales 201174|Actinobacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides cypB - 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase DYD1_k127_2952046_30 706587.Desti_3711 4.549e-21 101.0 COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin DYD1_k127_2952046_37 1254432.SCE1572_52700 5.482e-08 61.0 COG0711@1|root,COG0711@2|Bacteria,1Q25M@1224|Proteobacteria,437SR@68525|delta/epsilon subdivisions,2X31U@28221|Deltaproteobacteria,2Z2TD@29|Myxococcales 28221|Deltaproteobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B DYD1_k127_2952046_38 411459.RUMOBE_00322 1.444e-06 58.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,258VV@186801|Clostridia,3Y0ZV@572511|Blautia 186801|Clostridia C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - - - - - - - - - - ATP-synt_B DYD1_k127_2952046_31 868595.Desca_2632 6.505e-19 93.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,261U6@186807|Peptococcaceae 186801|Clostridia C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP DYD1_k127_2952046_1 316067.Geob_0449 6.376e-240 750.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,43T4A@69541|Desulfuromonadales 28221|Deltaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N DYD1_k127_2952046_15 706587.Desti_3706 3.085e-86 295.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2MQDF@213462|Syntrophobacterales 28221|Deltaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt DYD1_k127_2952046_0 316067.Geob_0447 1.132e-251 782.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,43TRP@69541|Desulfuromonadales 28221|Deltaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N DYD1_k127_2952046_27 269799.Gmet_3405 1.888e-26 114.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,43V31@69541|Desulfuromonadales 28221|Deltaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N DYD1_k127_2952046_4 443152.MDG893_15240 6.39e-178 570.0 COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria,1RYIP@1236|Gammaproteobacteria 1236|Gammaproteobacteria E ethanolamine utilization protein eutA GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - ko:K04019 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001 - - - EutA DYD1_k127_2952046_34 1134413.ANNK01000089_gene349 6.035e-16 88.0 COG0697@1|root,COG0697@2|Bacteria,1VM62@1239|Firmicutes,4HPP1@91061|Bacilli 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_2952046_22 1206744.BAGL01000050_gene955 1.255e-38 156.0 COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4G3XZ@85025|Nocardiaceae 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_2952046_26 203124.Tery_2073 9.73e-29 121.0 COG0662@1|root,COG0662@2|Bacteria,1GDUY@1117|Cyanobacteria 1117|Cyanobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_2952046_18 639283.Snov_4076 5.361e-61 220.0 COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria,3F0K5@335928|Xanthobacteraceae 28211|Alphaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain gci - 5.5.1.27 ko:K18983 ko00053,map00053 - R10847 RC03287 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N DYD1_k127_2954398_2 1173027.Mic7113_4237 1.695e-15 81.0 COG0642@1|root,COG2199@1|root,COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,1GHBX@1117|Cyanobacteria 1117|Cyanobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - 2.7.13.3 ko:K11527 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1 DYD1_k127_2954398_1 177437.HRM2_07130 7.41e-23 108.0 COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria,2MI5T@213118|Desulfobacterales 28221|Deltaproteobacteria F Cytidylate kinase-like family - - - - - - - - - - - - Cytidylate_kin2 DYD1_k127_2954398_0 316067.Geob_0052 3.621e-48 179.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria,43UR2@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam DYD1_k127_2965193_9 378806.STAUR_1662 4.765e-06 50.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 28221|Deltaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_2965193_2 331869.BAL199_29922 1.163e-61 217.0 COG5553@1|root,COG5553@2|Bacteria,1RD6A@1224|Proteobacteria,2U7HF@28211|Alphaproteobacteria,4BT3J@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S metal-dependent enzyme of the double-stranded beta helix superfamily - - - - - - - - - - - - - DYD1_k127_2965193_7 42256.RradSPS_3110 1.664e-23 103.0 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - - - - - - - - - - - DYD1_k127_2965193_8 317619.ANKN01000117_gene1295 8.029e-16 79.0 2E6Q0@1|root,331MP@2|Bacteria,1G9AF@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF4926) - - - - - - - - - - - - DUF4926 DYD1_k127_2965193_5 742725.HMPREF9450_01229 3.016e-41 162.0 COG1028@1|root,COG1028@2|Bacteria,4NEUB@976|Bacteroidetes,2FX2S@200643|Bacteroidia,22U0F@171550|Rikenellaceae 976|Bacteroidetes IQ KR domain - - 1.1.1.159,1.3.1.25 ko:K00076,ko:K05783 ko00121,ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00121,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113 RC00271,RC01326,RC01327 br01602,ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 DYD1_k127_2965193_1 243231.GSU2716 1.923e-75 264.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,42QXT@68525|delta/epsilon subdivisions,2WN0R@28221|Deltaproteobacteria,43T0X@69541|Desulfuromonadales 28221|Deltaproteobacteria S Sugar fermentation stimulation protein sfsA - - ko:K06206 - - - - ko00000 - - - SfsA DYD1_k127_2965193_0 316058.RPB_4416 4.769e-189 614.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD1_k127_2965193_3 1207076.ALAT01000204_gene1790 3.559e-57 203.0 COG1247@1|root,COG1247@2|Bacteria,1QU4K@1224|Proteobacteria,1T2Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_2965193_6 1274374.CBLK010000078_gene4153 3.442e-25 113.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,26TTZ@186822|Paenibacillaceae 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 DYD1_k127_2965193_4 321327.CYA_1203 6.564e-50 186.0 COG1011@1|root,COG1011@2|Bacteria,1G51I@1117|Cyanobacteria,1H0H2@1129|Synechococcus 1117|Cyanobacteria S Haloacid dehalogenase-like hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase DYD1_k127_2978640_1 1123368.AUIS01000024_gene953 3.435e-42 167.0 COG2890@1|root,COG2890@2|Bacteria,1MY5I@1224|Proteobacteria,1T26C@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase (PrmA) - - - - - - - - - - - - Methyltransf_31,PrmA DYD1_k127_2978640_0 756272.Plabr_0476 9.166e-46 179.0 COG2423@1|root,COG2423@2|Bacteria,2IXT1@203682|Planctomycetes 203682|Planctomycetes E ornithine cyclodeaminase mu-crystallin - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_2978640_3 298653.Franean1_4973 4.891e-06 58.0 COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria 201174|Actinobacteria C PFAM Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_2978640_2 502025.Hoch_5491 4.87e-42 163.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,437RC@68525|delta/epsilon subdivisions,2X304@28221|Deltaproteobacteria,2YTVQ@29|Myxococcales 28221|Deltaproteobacteria S methyltransferase - - - - - - - - - - - - PCMT DYD1_k127_2997400_0 237368.SCABRO_01504 2.539e-194 617.0 COG0659@1|root,COG0659@2|Bacteria,2IX8K@203682|Planctomycetes 203682|Planctomycetes P secondary active sulfate transmembrane transporter activity - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - - DYD1_k127_2997400_11 648996.Theam_1342 6.175e-42 162.0 COG0406@1|root,COG0406@2|Bacteria,2G423@200783|Aquificae 200783|Aquificae G PFAM Phosphoglycerate mutase pgmA - 3.1.3.3 ko:K22305 ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130 - R00582 RC00017 ko00000,ko00001,ko01000 - - - His_Phos_1 DYD1_k127_2997400_6 1232410.KI421413_gene960 3.489e-85 306.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,43RYI@69541|Desulfuromonadales 28221|Deltaproteobacteria O SurA N-terminal domain nifM - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 DYD1_k127_2997400_1 1144275.COCOR_07387 4.654e-167 533.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales 28221|Deltaproteobacteria D Rod shape-determining protein mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD1_k127_2997400_9 933262.AXAM01000010_gene1379 8.218e-49 185.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales 28221|Deltaproteobacteria M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC DYD1_k127_2997400_2 1232437.KL662077_gene1920 8.299e-166 543.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales 28221|Deltaproteobacteria M Penicillin-binding Protein dimerisation domain mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_0928 PBP_dimer,Transpeptidase DYD1_k127_2997400_4 56780.SYN_00550 8.619e-111 370.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2MQBR@213462|Syntrophobacterales 28221|Deltaproteobacteria M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE DYD1_k127_2997400_10 335543.Sfum_1708 5.135e-44 163.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MS32@213462|Syntrophobacterales 28221|Deltaproteobacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD1_k127_2997400_5 338963.Pcar_0200 2.587e-108 370.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales 28221|Deltaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N DYD1_k127_2997400_7 401053.AciPR4_1066 1.771e-70 243.0 COG0302@1|root,COG0302@2|Bacteria,3Y2SP@57723|Acidobacteria,2JIR1@204432|Acidobacteriia 204432|Acidobacteriia H TIGRFAM GTP cyclohydrolase I folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI DYD1_k127_2997400_8 671143.DAMO_0003 3.725e-70 245.0 COG0785@1|root,COG0785@2|Bacteria,2NPE4@2323|unclassified Bacteria 2|Bacteria O Cytochrome C biogenesis protein transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD DYD1_k127_2997400_12 225937.HP15_2144 7.349e-32 131.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,4677J@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thioredoxin-like resA - - - - - - - - - - - AhpC-TSA,Redoxin DYD1_k127_2997400_13 1415780.JPOG01000001_gene75 3.905e-18 94.0 COG2267@1|root,COG2267@2|Bacteria,1PWD0@1224|Proteobacteria,1S8KS@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_6 DYD1_k127_2997400_3 671143.DAMO_1298 3.2e-136 446.0 COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria 2|Bacteria T COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_300402_1 234267.Acid_0452 3.651e-92 310.0 COG0247@1|root,COG0247@2|Bacteria,3Y6NT@57723|Acidobacteria 57723|Acidobacteria C Cysteine-rich domain - - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 DYD1_k127_300402_2 867845.KI911784_gene2016 5.214e-67 245.0 COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi,376EU@32061|Chloroflexia 32061|Chloroflexia C PFAM FAD linked oxidase domain protein - - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 DYD1_k127_300402_3 589865.DaAHT2_0263 8.612e-64 234.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42QM3@68525|delta/epsilon subdivisions,2WKI2@28221|Deltaproteobacteria,2MI4S@213118|Desulfobacterales 28221|Deltaproteobacteria M Lysin motif - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD1_k127_300402_4 163164.WD_0880 3.396e-08 65.0 COG5424@1|root,COG5424@2|Bacteria,1PV6D@1224|Proteobacteria,2V6N7@28211|Alphaproteobacteria,47F6F@766|Rickettsiales 766|Rickettsiales H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2 DYD1_k127_300402_0 330214.NIDE1289 4.452e-236 748.0 COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae 40117|Nitrospirae G Carbohydrate phosphorylase - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase DYD1_k127_3007860_17 247490.KSU1_D0201 1.993e-44 165.0 COG0399@1|root,COG0399@2|Bacteria,2J1H7@203682|Planctomycetes 203682|Planctomycetes J 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_3007860_2 671143.DAMO_1293 7.118e-155 505.0 COG0389@1|root,COG0389@2|Bacteria 2|Bacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346,ko:K14161 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C DYD1_k127_3007860_11 671143.DAMO_1294 1.303e-60 216.0 COG0468@1|root,COG0468@2|Bacteria 2|Bacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - ko:K03553,ko:K14160 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD1_k127_3007860_16 867903.ThesuDRAFT_00167 5.685e-48 179.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WCIP@538999|Clostridiales incertae sedis 186801|Clostridia K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 DYD1_k127_3007860_8 479434.Sthe_3486 6.768e-89 312.0 COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia 189775|Thermomicrobia S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - DYD1_k127_3007860_1 525904.Tter_1872 1.715e-181 579.0 COG1239@1|root,COG1239@2|Bacteria,2NQQG@2323|unclassified Bacteria 2|Bacteria H Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX chlI - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - iNJ661.Rv0958 Mg_chelatase,Sigma54_activat DYD1_k127_3007860_14 269799.Gmet_1638 1.641e-50 184.0 COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,43V0C@69541|Desulfuromonadales 28221|Deltaproteobacteria FG Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing - - 2.7.7.53 ko:K19710 ko00230,map00230 - R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 - - - CwfJ_C_1,HIT DYD1_k127_3007860_18 1267005.KB911265_gene3588 7.237e-28 116.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria,3N73M@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD1_k127_3007860_9 1232410.KI421418_gene2310 1.194e-76 267.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,43S2J@69541|Desulfuromonadales 28221|Deltaproteobacteria OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 DYD1_k127_3007860_0 1278073.MYSTI_04123 1.112e-215 684.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales 28221|Deltaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 DYD1_k127_3007860_12 1232410.KI421418_gene2307 4.971e-58 210.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,43VZJ@69541|Desulfuromonadales 28221|Deltaproteobacteria F Cytidylate kinase cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin DYD1_k127_3007860_4 1232410.KI421418_gene2306 2.98e-137 449.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,43TXZ@69541|Desulfuromonadales 28221|Deltaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase DYD1_k127_3007860_10 338963.Pcar_1886 6.606e-73 256.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2WJZ7@28221|Deltaproteobacteria,43S3M@69541|Desulfuromonadales 28221|Deltaproteobacteria E Prephenate dehydrogenase - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH DYD1_k127_3007860_3 330214.NIDE0421 2.436e-142 461.0 COG2876@1|root,COG2876@2|Bacteria,3J0A5@40117|Nitrospirae 40117|Nitrospirae E NeuB family - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 DYD1_k127_3007860_6 589865.DaAHT2_2672 6.47e-116 385.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2MIX3@213118|Desulfobacterales 28221|Deltaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_3007860_5 398767.Glov_2150 5.653e-122 401.0 COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT DYD1_k127_3007860_15 1219084.AP014508_gene741 4.345e-48 183.0 COG0564@1|root,COG0564@2|Bacteria,2GCKX@200918|Thermotogae 200918|Thermotogae J Responsible for synthesis of pseudouridine from uracil - - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_3007860_13 309798.COPRO5265_0558 1.19e-56 206.0 COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,248AA@186801|Clostridia,42F7Y@68295|Thermoanaerobacterales 186801|Clostridia IQ PFAM Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 DYD1_k127_3007860_7 195250.CM001776_gene1981 3.314e-103 353.0 COG0523@1|root,COG0523@2|Bacteria,1G1BG@1117|Cyanobacteria,1H03A@1129|Synechococcus 1117|Cyanobacteria S Cobalamin synthesis protein cobW C-terminal domain - - - - - - - - - - - - CobW_C,cobW DYD1_k127_301091_0 909663.KI867150_gene2735 2.681e-257 801.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales 28221|Deltaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD1_k127_301091_5 1282362.AEAC466_02065 9.673e-36 137.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,2KH3Y@204458|Caulobacterales 204458|Caulobacterales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD1_k127_301091_4 1380394.JADL01000007_gene4510 9.325e-69 242.0 COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,2TV0I@28211|Alphaproteobacteria,2JSKI@204441|Rhodospirillales 204441|Rhodospirillales O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C,GST_C_2,GST_N DYD1_k127_301091_6 398767.Glov_3185 1.353e-35 142.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2WQPS@28221|Deltaproteobacteria,43USX@69541|Desulfuromonadales 28221|Deltaproteobacteria Q MlaC protein - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD1_k127_301091_3 1191523.MROS_2369 2.526e-116 391.0 COG1007@1|root,COG1007@2|Bacteria 2|Bacteria C ATP synthesis coupled electron transport nuoN GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M DYD1_k127_301091_1 880073.Calab_2684 4.43e-187 600.0 COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria 2|Bacteria C NADH-quinone oxidoreductase, chain M nuoM2 - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M DYD1_k127_301091_2 1122605.KB893644_gene1416 1.552e-175 572.0 COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia 976|Bacteroidetes CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N DYD1_k127_301091_7 290397.Adeh_2578 4.873e-09 57.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42WIQ@68525|delta/epsilon subdivisions,2WS3A@28221|Deltaproteobacteria,2Z1V8@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD1_k127_3018443_3 192952.MM_2279 2.272e-84 295.0 COG0402@1|root,arCOG00695@2157|Archaea,2XTJS@28890|Euryarchaeota,2N91D@224756|Methanomicrobia 224756|Methanomicrobia F Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent dadD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 DYD1_k127_3018443_7 879212.DespoDRAFT_01850 3.97e-34 138.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2MK76@213118|Desulfobacterales 28221|Deltaproteobacteria Q DSBA-like thioredoxin domain - - - - - - - - - - - - DSBA DYD1_k127_3018443_6 497964.CfE428DRAFT_0398 1.397e-45 176.0 COG5483@1|root,COG5483@2|Bacteria,46TB0@74201|Verrucomicrobia 74201|Verrucomicrobia S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 DYD1_k127_3018443_8 1430331.EP10_09025 2.275e-30 134.0 COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1WEXZ@129337|Geobacillus 91061|Bacilli EGP Nucleoside H+ symporter ywbF - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like DYD1_k127_3018443_2 1267533.KB906741_gene405 2.305e-137 447.0 COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria,2JNCI@204432|Acidobacteriia 204432|Acidobacteriia P Ring hydroxylating alpha subunit (catalytic domain) - - - ko:K00479 - - - - ko00000 - - - Rieske,Ring_hydroxyl_A DYD1_k127_3018443_9 1231391.AMZF01000008_gene1542 1.722e-09 68.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_3018443_5 378806.STAUR_2326 9.346e-52 205.0 COG0642@1|root,COG3852@1|root,COG0642@2|Bacteria,COG3852@2|Bacteria,1NXDJ@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - 2.7.13.3 ko:K07716,ko:K20974 ko02020,ko02025,ko04112,map02020,map02025,map04112 M00511,M00820 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE,CHASE3,HATPase_c,HisKA,PAS_7,Response_reg DYD1_k127_3018443_4 1192034.CAP_6251 8.599e-66 238.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_3018443_1 1231391.AMZF01000094_gene113 4.044e-161 522.0 COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria 1224|Proteobacteria E ethanolamine utilization protein eutA GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - ko:K04019 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001 - - - EutA DYD1_k127_3022581_4 357808.RoseRS_3426 9.675e-21 93.0 2E90H@1|root,3339X@2|Bacteria,2GB2F@200795|Chloroflexi,377SX@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - DYD1_k127_3022581_3 411154.GFO_2569 5.354e-22 104.0 2DQP5@1|root,337VV@2|Bacteria,4P3M5@976|Bacteroidetes,1I922@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_3022581_7 667632.KB890183_gene978 2.257e-12 75.0 29WRR@1|root,30ICT@2|Bacteria,1PJZT@1224|Proteobacteria,2W8BE@28216|Betaproteobacteria,1K772@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3022581_0 330214.NIDE1812 4.198e-33 130.0 2ED2F@1|root,336ZC@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 DYD1_k127_3022581_6 1163617.SCD_n00293 8.185e-14 71.0 2C5EY@1|root,32YQJ@2|Bacteria,1N8K7@1224|Proteobacteria,2VZ2R@28216|Betaproteobacteria 28216|Betaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - DUF4160 DYD1_k127_3022581_1 324925.Ppha_0836 3.521e-31 124.0 COG3668@1|root,COG3668@2|Bacteria 2|Bacteria D Plasmid stabilization system - - - - - - - - - - - - ParE_toxin DYD1_k127_3022581_5 1173028.ANKO01000088_gene25 7.626e-15 78.0 2E4QQ@1|root,32ZJA@2|Bacteria,1G97D@1117|Cyanobacteria,1HD55@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_3022581_2 113395.AXAI01000005_gene3843 1.17e-23 100.0 298AC@1|root,31CAJ@2|Bacteria,1P0XH@1224|Proteobacteria,2UV0Z@28211|Alphaproteobacteria,3K4KY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Antitoxin Phd_YefM, type II toxin-antitoxin system - - - - - - - - - - - - PhdYeFM_antitox DYD1_k127_302904_1 1499967.BAYZ01000095_gene4149 4.921e-34 136.0 COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_302904_0 1288494.EBAPG3_13270 2.206e-163 523.0 COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,372QJ@32003|Nitrosomonadales 28216|Betaproteobacteria L THUMP rlmL - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 DYD1_k127_302904_2 1499967.BAYZ01000034_gene1071 2.089e-23 102.0 2E46N@1|root,32Z2M@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3040228_2 644801.Psest_2168 9.48e-06 50.0 2DQZR@1|root,339JT@2|Bacteria,1NH4G@1224|Proteobacteria,1SV2G@1236|Gammaproteobacteria,1Z3B5@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Protein of unknown function (DUF2934) - - - - - - - - - - - - DUF2934 DYD1_k127_3040228_1 1144310.PMI07_005585 8.787e-32 138.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_3040228_3 1485545.JQLW01000010_gene1524 1.992e-05 49.0 2EPHU@1|root,33H4F@2|Bacteria,1NNZ4@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_3040228_0 383372.Rcas_3335 5.663e-95 330.0 COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,376IG@32061|Chloroflexia 32061|Chloroflexia IQ PFAM AMP-dependent synthetase and ligase - - 6.1.3.1,6.2.1.3 ko:K01897,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD1_k127_3044287_4 1254432.SCE1572_51465 1.205e-42 160.0 COG0838@1|root,COG0838@2|Bacteria,1PPP3@1224|Proteobacteria,42VF4@68525|delta/epsilon subdivisions,2WRIV@28221|Deltaproteobacteria,2Z22Z@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 DYD1_k127_3044287_2 290397.Adeh_2572 3.708e-74 252.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2Z08H@29|Myxococcales 28221|Deltaproteobacteria C Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 DYD1_k127_3044287_3 404589.Anae109_1287 1.05e-55 199.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2WQB1@28221|Deltaproteobacteria,2Z1BP@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa DYD1_k127_3044287_0 290397.Adeh_2574 3.561e-146 472.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YWJS@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa DYD1_k127_3044287_1 448385.sce7563 1.383e-81 278.0 COG0265@1|root,COG1005@1|root,COG0265@2|Bacteria,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YYND@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh,PDZ_2 DYD1_k127_3072766_1 573063.Metin_1025 3.438e-79 279.0 COG0498@1|root,arCOG01434@2157|Archaea,2XT84@28890|Euryarchaeota,23QKS@183939|Methanococci 183939|Methanococci E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine thrC GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_3072766_0 1183438.GKIL_3640 2.642e-147 476.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1GBPU@1117|Cyanobacteria 1117|Cyanobacteria C PFAM FAD linked oxidase domain protein - - - - - - - - - - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8 DYD1_k127_3080071_6 1123368.AUIS01000032_gene1399 1.739e-72 251.0 COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,1RNSP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - Exo_endo_phos DYD1_k127_3080071_1 1123368.AUIS01000032_gene1398 1.393e-229 731.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Pfam SNARE associated Golgi protein - - - - - - - - - - - - PLDc,PLDc_2,SNARE_assoc DYD1_k127_3080071_4 1095769.CAHF01000013_gene3288 2.109e-115 380.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria,475IH@75682|Oxalobacteraceae 28216|Betaproteobacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD1_k127_3080071_2 1122604.JONR01000015_gene111 6.031e-165 526.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,1X52V@135614|Xanthomonadales 135614|Xanthomonadales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD1_k127_3080071_3 1122604.JONR01000015_gene110 6.413e-157 502.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1X3P3@135614|Xanthomonadales 135614|Xanthomonadales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD1_k127_3080071_0 1502851.FG93_00553 4.894e-241 761.0 COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,2TW58@28211|Alphaproteobacteria,3JW0I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_3080071_5 316056.RPC_3037 1.054e-94 317.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_310349_1 384765.SIAM614_17849 1.546e-122 406.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - - - - - - - - - - DctM DYD1_k127_310349_9 331869.BAL199_03139 5.796e-24 108.0 COG3090@1|root,COG3090@2|Bacteria,1N0N7@1224|Proteobacteria,2U65H@28211|Alphaproteobacteria,4BQMH@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD1_k127_310349_4 1380358.JADJ01000017_gene1454 6.879e-99 333.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RYAQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP DYD1_k127_310349_8 696369.KI912183_gene2503 1.388e-38 153.0 2AV93@1|root,31M00@2|Bacteria,1V94N@1239|Firmicutes,251VU@186801|Clostridia,265SD@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_310349_5 138119.DSY0993 1.499e-60 221.0 COG1145@1|root,COG1145@2|Bacteria,1UIDU@1239|Firmicutes,25EIV@186801|Clostridia,267A7@186807|Peptococcaceae 186801|Clostridia C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - - DYD1_k127_310349_2 1038869.AXAN01000050_gene5913 4.698e-122 403.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VI9Q@28216|Betaproteobacteria,1K19V@119060|Burkholderiaceae 28216|Betaproteobacteria E Aminotransferase sgaA - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD1_k127_310349_3 439235.Dalk_4026 5.83e-104 354.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42YUK@68525|delta/epsilon subdivisions,2WTYA@28221|Deltaproteobacteria,2MMJC@213118|Desulfobacterales 28221|Deltaproteobacteria T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Sigma54_activat DYD1_k127_310349_7 443152.MDG893_15467 8.928e-54 203.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_310349_10 1144319.PMI16_02085 1.02e-21 103.0 COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2VNYN@28216|Betaproteobacteria,4733Q@75682|Oxalobacteraceae 28216|Betaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 DYD1_k127_310349_6 443152.MDG893_15260 3.752e-54 203.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_310349_0 443152.MDG893_15387 4.306e-134 444.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD1_k127_3141718_2 1123023.JIAI01000002_gene4973 1.405e-06 55.0 COG0715@1|root,COG0715@2|Bacteria,2IDBN@201174|Actinobacteria 201174|Actinobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_3141718_0 1394178.AWOO02000017_gene6725 1.697e-44 173.0 COG0346@1|root,COG0346@2|Bacteria,2GM8H@201174|Actinobacteria,4EIS4@85012|Streptosporangiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily bnzC - - - - - - - - - - - Glyoxalase DYD1_k127_3141718_1 1123060.JONP01000027_gene3502 2.415e-21 96.0 COG0596@1|root,COG0596@2|Bacteria,1N54X@1224|Proteobacteria,2U1C2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_3142249_4 1407650.BAUB01000019_gene2485 1.581e-17 91.0 COG4783@1|root,COG4783@2|Bacteria,1G1TE@1117|Cyanobacteria,1H0DF@1129|Synechococcus 1117|Cyanobacteria S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD1_k127_3142249_8 443144.GM21_0541 9.088e-09 59.0 28T91@1|root,2ZFHN@2|Bacteria,1P659@1224|Proteobacteria,433I9@68525|delta/epsilon subdivisions,2WX6G@28221|Deltaproteobacteria,43VY2@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3142249_1 1232410.KI421421_gene3355 4.569e-119 395.0 COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,42QFN@68525|delta/epsilon subdivisions,2WKUY@28221|Deltaproteobacteria,43UG8@69541|Desulfuromonadales 28221|Deltaproteobacteria I Fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase DYD1_k127_3142249_7 1267534.KB906759_gene1941 3.605e-11 67.0 COG3280@1|root,COG3280@2|Bacteria,3Y2QG@57723|Acidobacteria,2JIFT@204432|Acidobacteriia 204432|Acidobacteriia G TIGRFAM Malto-oligosyltrehalose synthase - - 5.4.99.15 ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R09995 - ko00000,ko00001,ko00002,ko01000 - GH13 - Alpha-amylase DYD1_k127_3142249_0 671143.DAMO_2996 0.0 1027.0 COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria 2|Bacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM DYD1_k127_3142249_3 903814.ELI_0518 3.364e-19 93.0 COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia,25WRS@186806|Eubacteriaceae 186801|Clostridia K CarD-like/TRCF domain carD - - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF DYD1_k127_3142249_2 237368.SCABRO_02165 2.692e-40 162.0 COG0589@1|root,COG0589@2|Bacteria,2J12B@203682|Planctomycetes 203682|Planctomycetes T COG0589 Universal stress protein UspA and related - - - ko:K14055 - - - - ko00000 - - - Usp DYD1_k127_3147515_3 1288494.EBAPG3_23590 1.606e-18 95.0 COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,2VRF2@28216|Betaproteobacteria,372Z0@32003|Nitrosomonadales 28216|Betaproteobacteria M Domain of unknown function (DUF4398) - - - - - - - - - - - - DUF4398,OmpA DYD1_k127_3147515_1 945713.IALB_0263 2.261e-56 218.0 COG5000@1|root,COG5000@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - 2.7.13.3 ko:K07710,ko:K10942 ko02020,ko05111,map02020,map05111 M00500,M00515 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS DYD1_k127_3147515_0 324925.Ppha_1319 1.856e-145 473.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K02481,ko:K07713,ko:K07714 ko02020,map02020 M00499,M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_3147515_2 1192034.CAP_7340 5.974e-52 188.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg DYD1_k127_3184471_3 1123023.JIAI01000004_gene7881 9.004e-17 81.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process - - - - - - - - - - - - Ribonuc_L-PSP DYD1_k127_3184471_4 1408422.JHYF01000001_gene2684 2.549e-14 78.0 COG0346@1|root,COG0346@2|Bacteria,1V422@1239|Firmicutes,24JKI@186801|Clostridia,36K8C@31979|Clostridiaceae 186801|Clostridia E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K21252 - - - - ko00000,ko01504 - - - Glyoxalase DYD1_k127_3184471_0 195105.CN97_19055 2.656e-150 492.0 COG0747@1|root,COG0747@2|Bacteria,1MWGY@1224|Proteobacteria,2TR73@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0747 ABC-type dipeptide transport system, periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_3184471_1 365046.Rta_15490 1.251e-56 209.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria 28216|Betaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - 4.1.1.3,5.4.2.9 ko:K01003,ko:K01841 ko00440,ko00620,ko01100,ko01120,ko01130,map00440,map00620,map01100,map01120,map01130 - R00217,R00661 RC00040,RC02792 ko00000,ko00001,ko01000 - - - PEP_mutase DYD1_k127_3184471_2 1144310.PMI07_005447 1.142e-54 205.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_3211269_1 196367.JNFG01000009_gene6356 1.365e-58 217.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria,1KDTM@119060|Burkholderiaceae 28216|Betaproteobacteria C CoA-transferase family III bbsE - 2.8.3.15 ko:K07543 ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220 M00418 R05588 RC00014,RC00137 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 DYD1_k127_3211269_0 1435356.Y013_22440 2.769e-70 253.0 COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4FW1X@85025|Nocardiaceae 201174|Actinobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_3211269_3 1038860.AXAP01000097_gene5007 6.727e-35 147.0 COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_3211269_4 1122603.ATVI01000005_gene3871 1.182e-05 53.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 DYD1_k127_3211269_2 240292.Ava_1239 2.436e-50 182.0 COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HQBR@1161|Nostocales 1117|Cyanobacteria J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 DYD1_k127_3228616_4 1209989.TepiRe1_0449 3.445e-55 204.0 COG2513@1|root,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,24AC5@186801|Clostridia,42I3M@68295|Thermoanaerobacterales 186801|Clostridia G Isocitrate lyase family prpB - 4.1.3.30,4.1.3.32 ko:K03417,ko:K20454 ko00640,ko00760,ko01120,map00640,map00760,map01120 - R00409,R01355 RC00286,RC00287,RC01810 ko00000,ko00001,ko01000 - - - PEP_mutase DYD1_k127_3228616_1 1266925.JHVX01000007_gene2418 1.541e-78 265.0 COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VRJ0@28216|Betaproteobacteria,374MK@32003|Nitrosomonadales 28216|Betaproteobacteria S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt DYD1_k127_3228616_5 1403819.BATR01000132_gene4686 2.216e-53 190.0 COG3795@1|root,COG3795@2|Bacteria,46V6E@74201|Verrucomicrobia,2IVM1@203494|Verrucomicrobiae 203494|Verrucomicrobiae S YCII-related domain - - - - - - - - - - - - YCII DYD1_k127_3228616_3 342113.DM82_6119 4.144e-62 216.0 COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VSH3@28216|Betaproteobacteria,1K72M@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM DGPFAETKE family protein - - - - - - - - - - - - YCII DYD1_k127_3228616_7 2002.JOEQ01000031_gene1648 2.862e-43 161.0 COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4EPKG@85012|Streptosporangiales 201174|Actinobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - - - - - - - - - - ThiS DYD1_k127_3228616_0 240015.ACP_1948 6.498e-224 697.0 COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia 204432|Acidobacteriia S cellulose binding - - - - - - - - - - - - BNR DYD1_k127_3228616_2 1411123.JQNH01000001_gene807 3.638e-63 219.0 COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2U5A4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K04750 - - - - ko00000 - - - 3-dmu-9_3-mt DYD1_k127_3228616_6 1116472.MGMO_35c00160 7.344e-51 182.0 COG3795@1|root,COG3795@2|Bacteria,1RK95@1224|Proteobacteria,1S6H7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII DYD1_k127_3228616_8 118173.KB235914_gene3477 1.22e-28 115.0 COG4941@1|root,COG4941@2|Bacteria,1G1YQ@1117|Cyanobacteria,1H7AG@1150|Oscillatoriales 1117|Cyanobacteria K RNA polymerase, sigma subunit, ECF family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_3243308_6 1192034.CAP_3447 2.691e-106 357.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,42RUS@68525|delta/epsilon subdivisions,2WNWT@28221|Deltaproteobacteria,2YWXA@29|Myxococcales 28221|Deltaproteobacteria S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like DYD1_k127_3243308_22 1125863.JAFN01000001_gene1593 9.042e-32 129.0 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,42SXV@68525|delta/epsilon subdivisions,2WPSN@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF1178) - - - - - - - - - - - - DUF1178 DYD1_k127_3243308_7 3847.GLYMA17G26230.3 2.043e-99 334.0 COG0115@1|root,KOG0975@2759|Eukaryota,37N35@33090|Viridiplantae,3G9PH@35493|Streptophyta,4JJUG@91835|fabids 35493|Streptophyta E Branched-chain-amino-acid aminotransferase-like protein 3 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008153,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046482,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.3.38 ko:K18482 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 DYD1_k127_3243308_0 330214.NIDE1868 0.0 1753.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3J0UH@40117|Nitrospirae 40117|Nitrospirae H Pterin binding enzyme - - 2.1.1.13,2.1.1.258 ko:K00548,ko:K15023 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230 M00017,M00377 R00946,R02289,R09365,R10243 RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans DYD1_k127_3243308_18 234267.Acid_5272 2.807e-43 171.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,3Y7FH@57723|Acidobacteria 57723|Acidobacteria K Hypothetical methyltransferase - - - - - - - - - - - - HTH_5,Methyltransf_11 DYD1_k127_3243308_17 264462.Bd3638 3.85e-45 174.0 COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,42S7K@68525|delta/epsilon subdivisions,2MU2H@213481|Bdellovibrionales,2WQI0@28221|Deltaproteobacteria 213481|Bdellovibrionales S DTW - - - ko:K05812 - - - - ko00000 - - - DTW DYD1_k127_3243308_13 316067.Geob_0615 1.31e-58 212.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,43UT3@69541|Desulfuromonadales 28221|Deltaproteobacteria S PFAM Phosphoribosyltransferase - - - - - - - - - - - - Pribosyltran DYD1_k127_3243308_1 443143.GM18_4206 1.358e-186 597.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,43T5X@69541|Desulfuromonadales 28221|Deltaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N DYD1_k127_3243308_20 56780.SYN_01339 3.866e-38 147.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2MQM6@213462|Syntrophobacterales 28221|Deltaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD1_k127_3243308_14 1232410.KI421412_gene397 2.328e-56 203.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,43TRZ@69541|Desulfuromonadales 28221|Deltaproteobacteria F Cytidylyltransferase-like nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_3200 CTP_transf_like DYD1_k127_3243308_2 1123371.ATXH01000038_gene1353 1.182e-170 546.0 COG0014@1|root,COG0014@2|Bacteria,2GH1U@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_3243308_5 269799.Gmet_3198 3.624e-110 367.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,43SXM@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_3198 AA_kinase,PUA DYD1_k127_3243308_3 760568.Desku_0428 3.181e-123 404.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25ZZB@186807|Peptococcaceae 186801|Clostridia S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 DYD1_k127_3243308_21 1121403.AUCV01000010_gene1393 5.559e-34 133.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MKMM@213118|Desulfobacterales 28221|Deltaproteobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 DYD1_k127_3243308_23 589865.DaAHT2_1159 1.885e-29 120.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2MKN7@213118|Desulfobacterales 28221|Deltaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p DYD1_k127_3243308_19 1382356.JQMP01000003_gene2350 1.483e-39 153.0 COG1846@1|root,COG1846@2|Bacteria,2G8V5@200795|Chloroflexi 200795|Chloroflexi K Winged helix DNA-binding domain - - - - - - - - - - - - MarR_2 DYD1_k127_3243308_10 1173263.Syn7502_03006 5.184e-74 259.0 COG0600@1|root,COG0600@2|Bacteria,1G1ZK@1117|Cyanobacteria,1GZMV@1129|Synechococcus 1117|Cyanobacteria P ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_3243308_12 330214.NIDE4332 3.465e-70 242.0 COG1704@1|root,COG1704@2|Bacteria 2|Bacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA DYD1_k127_3243308_15 269799.Gmet_1372 4.081e-56 209.0 COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria,43S55@69541|Desulfuromonadales 28221|Deltaproteobacteria S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase DYD1_k127_3243308_16 1232410.KI421421_gene3802 2.691e-46 175.0 COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,42QZE@68525|delta/epsilon subdivisions,2WMQH@28221|Deltaproteobacteria,43W06@69541|Desulfuromonadales 28221|Deltaproteobacteria S Membrane - - - ko:K08988 - - - - ko00000 - - - TPM_phosphatase DYD1_k127_3243308_24 756883.Halar_3143 4.123e-05 55.0 COG0477@1|root,arCOG00134@2157|Archaea 756883.Halar_3143|- EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - - DYD1_k127_3243308_9 330214.NIDE3764 3.085e-83 285.0 28PNA@1|root,2ZCB3@2|Bacteria 2|Bacteria S Transglycosylase SLT domain - - - - - - - - - - - - SLT DYD1_k127_3243308_4 760568.Desku_0802 2.132e-118 406.0 COG1042@1|root,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,260BP@186807|Peptococcaceae 186801|Clostridia C TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD1_k127_3243308_8 1123501.KB902297_gene3631 7.875e-98 331.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 DYD1_k127_3243308_11 105422.BBPM01000113_gene3362 9.196e-74 261.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,2NKS5@228398|Streptacidiphilus 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_3253456_0 269799.Gmet_0071 2.649e-210 689.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales 28221|Deltaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE DYD1_k127_3253456_9 1173023.KE650771_gene2965 3.8e-11 70.0 COG3744@1|root,COG3744@2|Bacteria,1GKMF@1117|Cyanobacteria,1JME0@1189|Stigonemataceae 1117|Cyanobacteria S PIN domain - - - - - - - - - - - - PIN DYD1_k127_3253456_6 706587.Desti_5142 1.846e-34 143.0 COG1102@1|root,COG1102@2|Bacteria,1R82J@1224|Proteobacteria,42M5Z@68525|delta/epsilon subdivisions,2WMEJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Cytidylate kinase-like family - - - - - - - - - - - - Cytidylate_kin2 DYD1_k127_3253456_5 754035.Mesau_00474 7.183e-50 181.0 COG3791@1|root,COG3791@2|Bacteria,1RBIH@1224|Proteobacteria,2U5D0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA DYD1_k127_3253456_1 1385519.N801_15195 5.151e-151 514.0 COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae 201174|Actinobacteria T GAF domain - - - - - - - - - - - - DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg DYD1_k127_3253456_2 76114.p2A120 3.404e-121 405.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_3253456_3 479432.Sros_0339 8.352e-77 269.0 COG2141@1|root,COG2141@2|Bacteria,2HF69@201174|Actinobacteria,4ENCI@85012|Streptosporangiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_3253456_4 234267.Acid_1970 3.811e-72 258.0 COG1506@1|root,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - - - - - - - - - - - CBM_2,DUF2048,Peptidase_S9 DYD1_k127_3253456_7 338969.Rfer_3515 1.261e-24 108.0 COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2VTNF@28216|Betaproteobacteria,4AF7C@80864|Comamonadaceae 28216|Betaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25,Ubie_methyltran DYD1_k127_326876_3 518766.Rmar_0504 7.784e-41 151.0 COG1372@1|root,COG1690@1|root,COG1372@2|Bacteria,COG1690@2|Bacteria,4PJG7@976|Bacteroidetes,1FIJQ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L tRNA-splicing ligase RtcB rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB DYD1_k127_326876_0 1191523.MROS_0532 3.35e-144 466.0 COG1690@1|root,COG1690@2|Bacteria 2|Bacteria S RNA ligase activity rtcB GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB DYD1_k127_326876_1 717774.Marme_2124 1.361e-100 342.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1XKXZ@135619|Oceanospirillales 135619|Oceanospirillales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD1_k127_326876_5 1191523.MROS_0532 5.044e-09 58.0 COG1690@1|root,COG1690@2|Bacteria 2|Bacteria S RNA ligase activity rtcB GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB DYD1_k127_326876_6 497964.CfE428DRAFT_6311 8.054e-06 52.0 299BV@1|root,2ZWES@2|Bacteria,46WNG@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - DYD1_k127_326876_2 1123060.JONP01000001_gene1565 1.247e-78 270.0 COG1335@1|root,COG1335@2|Bacteria,1NZJ1@1224|Proteobacteria,2TV8X@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Hydrolase - - - - - - - - - - - - Isochorismatase DYD1_k127_326876_7 443144.GM21_0541 9.889e-05 48.0 28T91@1|root,2ZFHN@2|Bacteria,1P659@1224|Proteobacteria,433I9@68525|delta/epsilon subdivisions,2WX6G@28221|Deltaproteobacteria,43VY2@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_326876_4 1382306.JNIM01000001_gene1536 4.998e-11 64.0 COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi 200795|Chloroflexi E Methionine synthase vitamin-B12 independent - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_3269770_1 1205680.CAKO01000026_gene4597 6.367e-23 102.0 COG2128@1|root,COG2128@2|Bacteria,1RC52@1224|Proteobacteria,2U3FR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD1_k127_3269770_2 485913.Krac_1243 9.896e-09 60.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity ynjA - - ko:K07486 - - - - ko00000 - - - CMD DYD1_k127_3269770_0 935261.JAGL01000016_gene2798 1.553e-38 148.0 COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2UBR4@28211|Alphaproteobacteria,43KZ2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Small multidrug resistance protein sugE GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res DYD1_k127_3279940_4 395961.Cyan7425_0749 1.595e-44 165.0 COG2199@1|root,COG3706@2|Bacteria 2|Bacteria T GGDEF domain - - - - - - - - - - - - HisKA,PAS_8,PAS_9,Response_reg,SpoIIE DYD1_k127_3279940_0 1173024.KI912149_gene6518 1.205e-237 766.0 COG0814@1|root,COG0814@2|Bacteria,1G4RP@1117|Cyanobacteria 1117|Cyanobacteria E amino acid - - - - - - - - - - - - - DYD1_k127_3279940_1 765420.OSCT_2174 2.68e-117 384.0 COG0455@1|root,COG0455@2|Bacteria,2G9ZU@200795|Chloroflexi,3772G@32061|Chloroflexia 32061|Chloroflexia D NUBPL iron-transfer P-loop NTPase - - - - - - - - - - - - AAA_31 DYD1_k127_3279940_2 1356854.N007_12890 4.335e-71 253.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HD58@91061|Bacilli 91061|Bacilli E Ornithine cyclodeaminase - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_3279940_3 443152.MDG893_15080 7.188e-56 203.0 COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,1RQJ7@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Isochorismatase hydrolase - - - - - - - - - - - - Isochorismatase DYD1_k127_3279940_5 1123290.AUDQ01000016_gene840 1.253e-41 166.0 COG0006@1|root,COG0006@2|Bacteria,1V5I8@1239|Firmicutes 1239|Firmicutes E Creatinase/Prolidase N-terminal domain - - - - - - - - - - - - Creatinase_N,Peptidase_M24 DYD1_k127_3296492_2 671143.DAMO_2127 2.488e-65 238.0 COG0628@1|root,COG0628@2|Bacteria 2|Bacteria D permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport DYD1_k127_3296492_5 595460.RRSWK_06191 4.566e-09 59.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD1_k127_3296492_4 595460.RRSWK_06191 1.22e-09 63.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD1_k127_3296492_1 383372.Rcas_2527 3.442e-71 250.0 COG3118@1|root,COG3118@2|Bacteria,2G90Y@200795|Chloroflexi,376KV@32061|Chloroflexia 32061|Chloroflexia O PFAM Thioredoxin domain - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin DYD1_k127_3296492_0 1379281.AVAG01000031_gene106 3.881e-302 957.0 COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2WJPV@28221|Deltaproteobacteria,2M8WP@213115|Desulfovibrionales 28221|Deltaproteobacteria C Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - iAF987.Gmet_3512 Aldedh,Pro_dh DYD1_k127_3296492_3 261292.Nit79A3_0757 5.78e-31 125.0 COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2WBPR@28216|Betaproteobacteria,372CS@32003|Nitrosomonadales 28216|Betaproteobacteria S Galactose oxidase, central domain - - - - - - - - - - - - Kelch_1 DYD1_k127_3306905_0 234267.Acid_7446 3.445e-33 136.0 2C8FH@1|root,33NBI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3306905_2 1411123.JQNH01000001_gene2502 7.223e-09 59.0 COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S glyoxalase bleomycin resistance protein dioxygenase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase DYD1_k127_3306905_3 272134.KB731324_gene5438 0.0001135 55.0 COG1672@1|root,COG5635@1|root,COG1672@2|Bacteria,COG5635@2|Bacteria,1G192@1117|Cyanobacteria,1H737@1150|Oscillatoriales 1117|Cyanobacteria T Ntpase (Nacht family) - - - - - - - - - - - - NACHT,TIR_2 DYD1_k127_3306905_1 301.JNHE01000002_gene2382 1.801e-17 83.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M mechanosensitive ion channel - - - - - - - - - - - - MS_channel DYD1_k127_3317067_0 392499.Swit_0904 1.703e-134 444.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,2K6JZ@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the UbiD family - - 4.1.1.98 ko:K03182,ko:K16874 ko00130,ko00365,ko01100,ko01110,ko01120,map00130,map00365,map01100,map01110,map01120 M00117 R04985,R04986,R10213 RC00391,RC03086 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_3317067_6 1123288.SOV_1c04590 1.94e-05 56.0 COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4H3E3@909932|Negativicutes 909932|Negativicutes P NMT1 THI5-like protein - - - - - - - - - - - - NMT1,NMT1_2 DYD1_k127_3317067_4 1122135.KB893157_gene355 1.616e-25 113.0 COG0457@1|root,COG0457@2|Bacteria,1N6TJ@1224|Proteobacteria,2UG5W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_12,TPR_16,TPR_19,TPR_2 DYD1_k127_3317067_7 1408224.SAMCCGM7_c0244 0.0001049 53.0 COG3473@1|root,COG3473@2|Bacteria 2|Bacteria Q Maleate cis-trans isomerase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD1_k127_3317067_5 1123376.AUIU01000016_gene234 4.579e-14 76.0 COG2823@1|root,COG2823@2|Bacteria 2|Bacteria S hyperosmotic response - - - ko:K04065 - - - - ko00000 - - - BON DYD1_k127_3317067_1 177437.HRM2_34570 1.087e-110 373.0 COG0477@1|root,COG2814@2|Bacteria,1R9V9@1224|Proteobacteria,42Q1C@68525|delta/epsilon subdivisions,2WK7P@28221|Deltaproteobacteria,2MMQA@213118|Desulfobacterales 28221|Deltaproteobacteria EGP Major Facilitator Superfamily - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 DYD1_k127_3317067_2 402881.Plav_2952 9.378e-69 241.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,1JNTA@119043|Rhodobiaceae 28211|Alphaproteobacteria K Sir2 family MA20_30275 - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 DYD1_k127_3317067_3 518766.Rmar_2510 1.681e-64 227.0 COG2267@1|root,COG2267@2|Bacteria,4PKJZ@976|Bacteroidetes,1FIMU@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes I Thioesterase domain - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_3333620_3 443152.MDG893_15295 3.636e-53 201.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_3333620_1 1382306.JNIM01000001_gene3478 1.593e-108 372.0 COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi 200795|Chloroflexi EH Belongs to the TPP enzyme family - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N,adh_short DYD1_k127_3333620_2 443152.MDG893_15467 1.553e-55 207.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_3333620_4 330084.JNYZ01000047_gene2915 3.894e-52 200.0 COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,4EBZH@85010|Pseudonocardiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_3333620_5 933262.AXAM01000172_gene934 2.291e-41 154.0 COG2337@1|root,COG2337@2|Bacteria,1N1DE@1224|Proteobacteria,42WAI@68525|delta/epsilon subdivisions,2WRAJ@28221|Deltaproteobacteria,2MNJZ@213118|Desulfobacterales 28221|Deltaproteobacteria T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD1_k127_3333620_7 589865.DaAHT2_0744 5.698e-19 88.0 COG0864@1|root,COG0864@2|Bacteria,1N84E@1224|Proteobacteria,42VWB@68525|delta/epsilon subdivisions,2WRHU@28221|Deltaproteobacteria,2MNZW@213118|Desulfobacterales 28221|Deltaproteobacteria K Ribbon-helix-helix protein, copG family - - - - - - - - - - - - RHH_1 DYD1_k127_3333620_6 1163617.SCD_n00171 5.962e-33 134.0 COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,2VPK0@28216|Betaproteobacteria 28216|Betaproteobacteria L restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_N,Mrr_cat DYD1_k127_3333620_0 1429916.X566_14890 9.641e-145 467.0 COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria,3K3FV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase DYD1_k127_3336885_6 243231.GSU2656 5.77e-117 388.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria,43TUD@69541|Desulfuromonadales 28221|Deltaproteobacteria C e3 binding domain bkdF - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_3336885_2 644966.Tmar_1672 4.223e-138 445.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,249UD@186801|Clostridia 186801|Clostridia C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_3336885_5 269799.Gmet_2509 7.597e-131 426.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,43UJJ@69541|Desulfuromonadales 28221|Deltaproteobacteria C Dehydrogenase E1 component bkdA - 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD1_k127_3336885_3 880073.Calab_0218 2.611e-134 444.0 COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria 2|Bacteria I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_2215 Thiolase_C,Thiolase_N DYD1_k127_3336885_4 986075.CathTA2_1596 1.921e-132 441.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli 91061|Bacilli I acyl-CoA dehydrogenase mmgC - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_3336885_0 330214.NIDE3118 4.931e-216 683.0 COG1884@1|root,COG1884@2|Bacteria 2|Bacteria I Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmA - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase DYD1_k127_3336885_8 479432.Sros_1242 3.466e-48 176.0 COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4EJ0E@85012|Streptosporangiales 201174|Actinobacteria I B12 binding domain icmB - 5.4.99.2 ko:K01849 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding DYD1_k127_3336885_1 671143.DAMO_0590 6.298e-141 458.0 COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria 2|Bacteria I Dehydrogenase yngJ GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 ko:K00248,ko:K11410,ko:K18244 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_3336885_7 706587.Desti_3802 1.111e-66 233.0 COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,42NBN@68525|delta/epsilon subdivisions,2WK8A@28221|Deltaproteobacteria,2MQRT@213462|Syntrophobacterales 28221|Deltaproteobacteria E TIGRFAM LAO AO transport system ATPase - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK DYD1_k127_3356442_1 56780.SYN_02280 3.98e-08 62.0 COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,43B7B@68525|delta/epsilon subdivisions 1224|Proteobacteria S RDD family - - - - - - - - - - - - DUF4339,RDD DYD1_k127_3356442_0 1449126.JQKL01000018_gene3295 8.641e-50 186.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,2691X@186813|unclassified Clostridiales 186801|Clostridia J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA DYD1_k127_3382972_1 690850.Desaf_0463 1.862e-34 138.0 COG0457@1|root,COG0457@2|Bacteria 690850.Desaf_0463|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_3382972_0 861299.J421_0739 1.693e-165 530.0 COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Glucose / Sorbosone dehydrogenase - - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH DYD1_k127_3382972_3 1283300.ATXB01000001_gene2084 6.645e-12 70.0 COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria,1XFER@135618|Methylococcales 135618|Methylococcales M Domain of unknown function (DUF4398) - - - - - - - - - - - - DUF4398,OmpA DYD1_k127_3382972_2 472759.Nhal_2790 6.66e-14 77.0 2E41E@1|root,32YY1@2|Bacteria,1NGB3@1224|Proteobacteria,1SDTK@1236|Gammaproteobacteria,1X1PQ@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4398) - - - - - - - - - - - - DUF4398 DYD1_k127_3384994_18 1485545.JQLW01000001_gene1478 6.001e-15 75.0 COG0267@1|root,COG0267@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 DYD1_k127_3384994_2 404380.Gbem_0918 1.088e-218 684.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria 28221|Deltaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD1_k127_3384994_11 525367.HMPREF0556_10489 7.809e-56 204.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,26J72@186820|Listeriaceae 91061|Bacilli H Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind DYD1_k127_3384994_8 316067.Geob_1523 1.561e-69 250.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,43T2W@69541|Desulfuromonadales 28221|Deltaproteobacteria S PFAM permease YjgP YjgQ family protein lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ DYD1_k127_3384994_14 1121918.ARWE01000001_gene1942 8.87e-44 173.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,43RYS@69541|Desulfuromonadales 28221|Deltaproteobacteria S Predicted permease YjgP/YjgQ family lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ DYD1_k127_3384994_4 269799.Gmet_0608 6.442e-118 389.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,43TEU@69541|Desulfuromonadales 28221|Deltaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD1_k127_3384994_13 1122134.KB893651_gene1996 3.313e-48 175.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1XJHH@135619|Oceanospirillales 135619|Oceanospirillales J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 DYD1_k127_3384994_12 515635.Dtur_1014 7.202e-52 186.0 COG0102@1|root,COG0102@2|Bacteria 2|Bacteria J mRNA binding rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 DYD1_k127_3384994_17 870967.VIS19158_11708 2.614e-22 100.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1XXZQ@135623|Vibrionales 135623|Vibrionales L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD1_k127_3384994_0 404589.Anae109_3418 0.0 1094.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales 28221|Deltaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon-2 - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD1_k127_3384994_3 1192034.CAP_8960 8.726e-200 629.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales 28221|Deltaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX DYD1_k127_3384994_6 868864.Dester_0010 5.707e-94 311.0 COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae 200783|Aquificae O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease DYD1_k127_3384994_7 338963.Pcar_1690 9.131e-75 267.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria,43SAW@69541|Desulfuromonadales 28221|Deltaproteobacteria O Bacterial trigger factor protein (TF) C-terminus tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N DYD1_k127_3384994_16 1254432.SCE1572_44010 9.198e-27 112.0 COG3536@1|root,COG3536@2|Bacteria 2|Bacteria S Protein of unknown function (DUF971) - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - DUF971 DYD1_k127_3384994_10 1121468.AUBR01000001_gene469 1.031e-56 204.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,42GAD@68295|Thermoanaerobacterales 186801|Clostridia F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like DYD1_k127_3384994_5 289376.THEYE_A1385 2.46e-95 317.0 COG0689@1|root,COG0689@2|Bacteria,3J0B8@40117|Nitrospirae 40117|Nitrospirae J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C DYD1_k127_3384994_1 671143.DAMO_2373 9.564e-221 692.0 COG1012@1|root,COG1012@2|Bacteria,2NNW6@2323|unclassified Bacteria 2|Bacteria C Aldehyde dehydrogenase family - - 1.2.1.9 ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 M00308,M00633 R01058 RC00242 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_3384994_15 1167006.UWK_01620 1.192e-29 121.0 COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2WRHX@28221|Deltaproteobacteria,2MKPA@213118|Desulfobacterales 28221|Deltaproteobacteria S YGGT family - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT DYD1_k127_3384994_9 1125863.JAFN01000001_gene2304 1.885e-59 213.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N DYD1_k127_3384994_20 443144.GM21_0541 2.651e-11 68.0 28T91@1|root,2ZFHN@2|Bacteria,1P659@1224|Proteobacteria,433I9@68525|delta/epsilon subdivisions,2WX6G@28221|Deltaproteobacteria,43VY2@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3384994_26 1123366.TH3_09775 0.0003655 51.0 COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2TTU7@28211|Alphaproteobacteria,2JQHE@204441|Rhodospirillales 204441|Rhodospirillales S Peptidase family M48 - - - - - - - - - - - - LysM,Peptidase_M48 DYD1_k127_3444098_2 936136.ARRT01000006_gene3813 7.297e-27 123.0 COG2114@1|root,COG2114@2|Bacteria,1R4VB@1224|Proteobacteria,2TRX8@28211|Alphaproteobacteria,4B79H@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc DYD1_k127_3444098_0 381666.H16_B0901 6.477e-137 443.0 COG2267@1|root,COG2267@2|Bacteria,1P0FV@1224|Proteobacteria,2VZJF@28216|Betaproteobacteria 28216|Betaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_6 DYD1_k127_3444098_3 1229909.NSED_06560 4.544e-07 55.0 arCOG06790@1|root,arCOG06790@2157|Archaea,41T7J@651137|Thaumarchaeota 651137|Thaumarchaeota S Zn-finger in ubiquitin-hydrolases and other protein - - - - - - - - - - - - zf-UBP DYD1_k127_3444098_1 639030.JHVA01000001_gene3665 5.717e-51 185.0 COG1917@1|root,COG1917@2|Bacteria,3Y4Y3@57723|Acidobacteria,2JMS3@204432|Acidobacteriia 204432|Acidobacteriia S Cupin - - - - - - - - - - - - Cupin_2 DYD1_k127_3480927_2 316067.Geob_3362 2.161e-37 143.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,43UVT@69541|Desulfuromonadales 28221|Deltaproteobacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 DYD1_k127_3480927_3 1191523.MROS_0069 2.782e-17 83.0 COG0291@1|root,COG0291@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p DYD1_k127_3480927_1 411464.DESPIG_02476 6.243e-51 185.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2M933@213115|Desulfovibrionales 28221|Deltaproteobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N DYD1_k127_3480927_0 35841.BT1A1_2443 1.634e-228 723.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD DYD1_k127_3501152_0 1340493.JNIF01000004_gene975 7.676e-107 364.0 COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria 57723|Acidobacteria T Two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_3501152_2 1340493.JNIF01000003_gene1919 2.104e-29 134.0 COG5000@1|root,COG5000@2|Bacteria,3Y32Z@57723|Acidobacteria 57723|Acidobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA DYD1_k127_3501152_1 1121091.AUMP01000003_gene2614 4.481e-101 339.0 COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli 91061|Bacilli H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM DYD1_k127_3501152_3 399795.CtesDRAFT_PD5001 3.296e-14 79.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,4ABX0@80864|Comamonadaceae 28216|Betaproteobacteria O peptidase M48, Ste24p - - - - - - - - - - - - Peptidase_M48 DYD1_k127_3501581_1 194439.CT1729 1.248e-60 211.0 COG2189@1|root,COG2852@1|root,COG2189@2|Bacteria,COG2852@2|Bacteria,1FEW7@1090|Chlorobi 1090|Chlorobi L DNA methylase - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase DYD1_k127_3501581_0 402777.KB235904_gene3971 0.0 1380.0 COG1061@1|root,COG1061@2|Bacteria,1GR4G@1117|Cyanobacteria 1117|Cyanobacteria KL Type III restriction enzyme, res subunit - - 3.1.21.5 ko:K01156 - - - - ko00000,ko01000,ko02048 - - - ResIII DYD1_k127_3501581_2 457570.Nther_0807 2.275e-10 72.0 COG1508@1|root,COG1508@2|Bacteria,1VPTC@1239|Firmicutes,24VVK@186801|Clostridia 186801|Clostridia K bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding - - - - - - - - - - - - - DYD1_k127_3504589_2 392499.Swit_2091 1.239e-30 124.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2U2SV@28211|Alphaproteobacteria,2K9WC@204457|Sphingomonadales 204457|Sphingomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD1_k127_3504589_0 1144310.PMI07_005447 3.755e-49 188.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_3504589_1 289376.THEYE_A0183 1.729e-40 153.0 COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,3J1FD@40117|Nitrospirae 40117|Nitrospirae T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K10715 ko02020,ko02024,map02020,map02024 M00517 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD1_k127_3506145_3 383372.Rcas_3778 1.185e-06 54.0 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity - - - ko:K04767,ko:K07182 - - - - ko00000 - - - CBS DYD1_k127_3506145_0 671143.DAMO_1019 1.32e-197 626.0 COG1488@1|root,COG1488@2|Bacteria,2NNUE@2323|unclassified Bacteria 2|Bacteria H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase DYD1_k127_3506145_1 1123368.AUIS01000038_gene38 5.519e-75 257.0 COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,2NCU9@225057|Acidithiobacillales 225057|Acidithiobacillales S Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran DYD1_k127_3506145_2 338963.Pcar_0274 1.367e-42 162.0 COG0454@1|root,COG0456@2|Bacteria,1RF31@1224|Proteobacteria,42RUB@68525|delta/epsilon subdivisions,2WN97@28221|Deltaproteobacteria,43UM1@69541|Desulfuromonadales 28221|Deltaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_3522679_2 1191523.MROS_1180 5.709e-81 280.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion - - - - - - - - - - - - Band_7 DYD1_k127_3522679_1 40571.JOEA01000025_gene6005 4.74e-82 291.0 COG2368@1|root,COG2368@2|Bacteria,2GKIQ@201174|Actinobacteria,4DYKH@85010|Pseudonocardiales 201174|Actinobacteria Q PFAM 4-hydroxyphenylacetate 3-hydroxylase - - 1.14.14.8,1.14.14.9 ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 - R02698,R03299,R09517 RC00046 ko00000,ko00001,ko01000 - - - HpaB,HpaB_N DYD1_k127_3522679_7 570952.ATVH01000016_gene2318 3.822e-29 128.0 COG3409@1|root,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,2UGJH@28211|Alphaproteobacteria,2JU67@204441|Rhodospirillales 204441|Rhodospirillales M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 DYD1_k127_3522679_8 472759.Nhal_1696 1.25e-09 70.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WVXM@135613|Chromatiales 135613|Chromatiales P heavy metal translocating P-type ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase DYD1_k127_3522679_4 1173263.Syn7502_03004 6.53e-57 216.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_3522679_9 743525.TSC_c14590 6.427e-07 59.0 COG4585@1|root,COG4585@2|Bacteria,1WJNH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8 DYD1_k127_3522679_3 639030.JHVA01000001_gene3247 1.356e-63 238.0 COG3267@1|root,COG3267@2|Bacteria,3Y6P4@57723|Acidobacteria,2JKNX@204432|Acidobacteriia 204432|Acidobacteriia U AAA domain - - - - - - - - - - - - AAA_22 DYD1_k127_3522679_6 1547437.LL06_19570 1.672e-32 135.0 COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2V8CK@28211|Alphaproteobacteria,43QNT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1989) - - - - - - - - - - - - DUF1989 DYD1_k127_3522679_5 243232.MJ_1425 2.54e-55 207.0 COG2055@1|root,arCOG04874@2157|Archaea,2XVBT@28890|Euryarchaeota,23QEN@183939|Methanococci 183939|Methanococci C PFAM Malate L-lactate dehydrogenase comC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464,GO:0050545 1.1.1.337 ko:K05884 ko00680,map00680 M00358 R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_2 DYD1_k127_3522679_0 1054213.HMPREF9946_01776 5.203e-105 348.0 COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,2TU9V@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Acetyl xylan esterase (AXE1) - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 DYD1_k127_3523392_2 1192868.CAIU01000015_gene1977 1.163e-24 108.0 COG1703@1|root,COG1703@2|Bacteria,1R44P@1224|Proteobacteria,2TW2E@28211|Alphaproteobacteria 28211|Alphaproteobacteria E periplasmic protein kinase ArgK and related GTPases of G3E family - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK DYD1_k127_3523392_0 518766.Rmar_1427 2.186e-277 867.0 COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1FIMS@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes I AMP-binding enzyme C-terminal domain - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD1_k127_3523392_1 1313301.AUGC01000008_gene475 1.202e-142 467.0 COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes 976|Bacteroidetes E Belongs to the cysteine synthase cystathionine beta- synthase family - - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP DYD1_k127_3526542_8 506534.Rhein_0665 4.876e-10 68.0 28YFU@1|root,2ZKA4@2|Bacteria,1PA7U@1224|Proteobacteria,1SUU3@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3526542_2 478741.JAFS01000001_gene1338 1.15e-44 166.0 COG3501@1|root,COG3501@2|Bacteria 2|Bacteria T Rhs element vgr protein tssI GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0006464,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0009405,GO:0009987,GO:0016043,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033646,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043624,GO:0043656,GO:0043657,GO:0043933,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0046872,GO:0051261,GO:0051704,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:1901265,GO:1901363,GO:1901564 - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - Gp5_C,Phage_GPD,VRR_NUC DYD1_k127_3526542_6 179408.Osc7112_5431 2.793e-21 99.0 COG2442@1|root,COG2442@2|Bacteria,1G83Q@1117|Cyanobacteria,1HCXY@1150|Oscillatoriales 1117|Cyanobacteria S InterPro IPR007367 - - - - - - - - - - - - - DYD1_k127_3526542_1 237368.SCABRO_03671 7.321e-58 212.0 29Z27@1|root,30KZN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3526542_3 1298867.AUES01000085_gene3659 7.075e-44 169.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_3526542_4 189753.AXAS01000012_gene4337 6.377e-30 122.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_3526542_0 189753.AXAS01000041_gene2534 2.333e-85 293.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_3526542_7 189753.AXAS01000041_gene2534 2.189e-18 88.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_3526714_2 671143.DAMO_2217 5.319e-43 163.0 COG2854@1|root,COG2854@2|Bacteria 2|Bacteria Q intermembrane phospholipid transfer - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD1_k127_3526714_1 1183377.Py04_0847 6.398e-73 268.0 COG0028@1|root,arCOG01998@2157|Archaea,2XT5F@28890|Euryarchaeota,243I4@183968|Thermococci 183968|Thermococci E Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_3526714_0 1123501.KB902290_gene1571 3.938e-148 487.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transport system fused permease components - - - - - - - - - - - - DctM DYD1_k127_3527238_4 519989.ECTPHS_13617 8.059e-09 60.0 COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Excisionase - - - - - - - - - - - - HTH_17 DYD1_k127_3527238_1 1125863.JAFN01000001_gene1352 2.8e-117 394.0 COG0043@1|root,COG0043@2|Bacteria,1PZMY@1224|Proteobacteria,42RNW@68525|delta/epsilon subdivisions,2WNJN@28221|Deltaproteobacteria 28221|Deltaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - - - - - - - - - - UbiD DYD1_k127_3527238_5 425104.Ssed_2934 4.229e-07 57.0 COG1664@1|root,COG1664@2|Bacteria,1MZG6@1224|Proteobacteria,1RW7P@1236|Gammaproteobacteria,2QC0W@267890|Shewanellaceae 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin DYD1_k127_3527238_0 1131266.ARWQ01000009_gene962 2.275e-123 416.0 COG1001@1|root,arCOG00693@2157|Archaea,41SZH@651137|Thaumarchaeota 651137|Thaumarchaeota F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade - 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 DYD1_k127_3527238_3 693661.Arcve_0123 1.349e-19 97.0 COG1300@1|root,arCOG01994@2157|Archaea,2Y7CT@28890|Euryarchaeota,246FF@183980|Archaeoglobi 183980|Archaeoglobi S Stage II sporulation protein M - - - ko:K06384 - - - - ko00000 - - - SpoIIM DYD1_k127_3527238_2 345341.KUTG_03869 1.563e-46 180.0 COG2159@1|root,COG2159@2|Bacteria 2|Bacteria E amidohydrolase - - 4.1.1.45 ko:K03392,ko:K07045 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_3527238_6 243274.THEMA_05515 0.0009726 42.0 COG2008@1|root,COG2008@2|Bacteria,2GCFA@200918|Thermotogae 200918|Thermotogae E Threonine aldolase - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - iLJ478.TM1744 Beta_elim_lyase DYD1_k127_3530114_0 1125863.JAFN01000001_gene3100 6.246e-122 402.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM Acyl-CoA dehydrogenase - - 1.3.99.32 ko:K16173 ko00362,ko01120,map00362,map01120 - R05579 RC00052 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_3530114_1 1380394.JADL01000017_gene522 6.945e-104 347.0 COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,2JPUP@204441|Rhodospirillales 204441|Rhodospirillales I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_3531254_0 762982.HMPREF9442_00356 1.803e-32 143.0 COG1807@1|root,COG1807@2|Bacteria,4NKI5@976|Bacteroidetes,2FMT9@200643|Bacteroidia 976|Bacteroidetes M Psort location CytoplasmicMembrane, score 10.00 arnT - - - - - - - - - - - PMT_2 DYD1_k127_3531254_1 1120973.AQXL01000130_gene1244 1.183e-10 72.0 COG5424@1|root,COG5424@2|Bacteria,1VNTM@1239|Firmicutes,4HSNP@91061|Bacilli 91061|Bacilli H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2 DYD1_k127_3549229_3 671143.DAMO_2591 6.253e-91 316.0 2E0UX@1|root,32WC9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Phenol_MetA_deg DYD1_k127_3549229_2 671143.DAMO_2592 4.079e-94 318.0 COG2984@1|root,COG2984@2|Bacteria,2NPCT@2323|unclassified Bacteria 2|Bacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_3549229_1 395495.Lcho_0045 8.555e-127 416.0 COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria 28216|Betaproteobacteria T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg DYD1_k127_3549229_0 1380370.JIBA01000015_gene376 1.142e-143 485.0 COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae 201174|Actinobacteria T GAF domain - - - - - - - - - - - - DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg DYD1_k127_3549229_4 1449080.JQMV01000003_gene1187 0.000125 50.0 COG3809@1|root,COG3809@2|Bacteria,1WKCH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - zf-TFIIB DYD1_k127_3549229_5 1101188.KI912155_gene1091 0.0002762 46.0 COG4655@1|root,COG4655@2|Bacteria,2IGK1@201174|Actinobacteria 201174|Actinobacteria S Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad DYD1_k127_355323_1 1144310.PMI07_005447 4.353e-51 194.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_355323_0 1144310.PMI07_005449 1.486e-76 265.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,4BCQJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA,TctB DYD1_k127_356554_1 338966.Ppro_2164 8.361e-65 225.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase DYD1_k127_356554_0 589924.Ferp_0995 1.378e-185 596.0 COG0209@1|root,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,245VM@183980|Archaeoglobi 183980|Archaeoglobi F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD DYD1_k127_3589811_4 247490.KSU1_C0797 3.974e-22 105.0 COG3642@1|root,COG3642@2|Bacteria 247490.KSU1_C0797|- T kinase activity - - - - - - - - - - - - - DYD1_k127_3589811_1 1121405.dsmv_0519 9.958e-50 191.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,43AFG@68525|delta/epsilon subdivisions,2WKA9@28221|Deltaproteobacteria,2MI8V@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) - - - ko:K02841 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD1_k127_3589811_3 247490.KSU1_D0289 4.405e-25 116.0 COG3642@1|root,COG3642@2|Bacteria 2|Bacteria T kinase activity - - - - - - - - - - - - Kdo DYD1_k127_3589811_2 269799.Gmet_0887 6.8e-43 177.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,43TBY@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 39 arnT - - - - - - - - - - - PMT,PMT_2 DYD1_k127_3589811_0 247490.KSU1_D0291 1.93e-68 248.0 COG0438@1|root,COG0438@2|Bacteria,2IZ1G@203682|Planctomycetes 203682|Planctomycetes M PFAM Glycosyl transferase, group 1 - - - ko:K02844 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT4 - Glyco_transf_4,Glycos_transf_1 DYD1_k127_3589811_5 247490.KSU1_D0292 1.639e-15 87.0 COG3642@1|root,COG3642@2|Bacteria,2J189@203682|Planctomycetes 203682|Planctomycetes T Lipopolysaccharide kinase (Kdo/WaaP) family - - - - - - - - - - - - Kdo DYD1_k127_3589811_6 756272.Plabr_3963 2.376e-14 82.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 DYD1_k127_3591128_7 1206730.BAGA01000077_gene1105 6.754e-66 238.0 COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4FW1X@85025|Nocardiaceae 201174|Actinobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_3591128_11 880073.Calab_0535 2.593e-31 134.0 COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria 2|Bacteria I Belongs to the enoyl-CoA hydratase isomerase family crt - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_3591128_13 1121918.ARWE01000001_gene3348 4.052e-22 108.0 COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Cytidylate kinase-like family - - - - - - - - - - - - Cytidylate_kin2 DYD1_k127_3591128_8 113395.AXAI01000002_gene5235 4.445e-57 211.0 COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,3JWDH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_3591128_6 345341.KUTG_07033 7.417e-78 271.0 COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4EEIC@85010|Pseudonocardiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_3591128_2 195105.CN97_19055 2.416e-130 438.0 COG0747@1|root,COG0747@2|Bacteria,1MWGY@1224|Proteobacteria,2TR73@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0747 ABC-type dipeptide transport system, periplasmic component - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_3591128_3 195105.CN97_19060 1.91e-102 343.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR3F@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K15585 ko02010,map02010 M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD1_k127_3591128_4 195105.CN97_19065 1.198e-95 322.0 COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VETJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N DYD1_k127_3591128_1 237368.SCABRO_03313 7.755e-148 485.0 COG0469@1|root,COG0469@2|Bacteria,2IY60@203682|Planctomycetes 203682|Planctomycetes G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C DYD1_k127_3591128_5 1306990.BARG01000030_gene3384 4.007e-86 296.0 COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria 201174|Actinobacteria Q Pfam Cupin - - 1.13.11.38,1.13.11.4 ko:K00450,ko:K11948 ko00350,ko00624,ko01100,ko01120,map00350,map00624,map01100,map01120 - R02656,R07657 RC00764,RC00937 ko00000,ko00001,ko01000 - - - Cupin_2 DYD1_k127_3591128_10 608538.HTH_1212 3.655e-34 142.0 COG5424@1|root,COG5424@2|Bacteria 2|Bacteria H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ pqqC - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4 DYD1_k127_3591128_0 1379270.AUXF01000001_gene2176 1.714e-171 554.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1ZURW@142182|Gemmatimonadetes 142182|Gemmatimonadetes P Bacterial periplasmic substrate-binding proteins - - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 DYD1_k127_3591128_9 379066.GAU_3202 3.624e-54 208.0 COG1126@1|root,COG1126@2|Bacteria,1ZVAS@142182|Gemmatimonadetes 142182|Gemmatimonadetes E AAA domain, putative AbiEii toxin, Type IV TA system - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran DYD1_k127_3591128_12 1179778.PMM47T1_18605 3.296e-31 131.0 2B41E@1|root,31WRS@2|Bacteria,1P8VA@1224|Proteobacteria,1S1WR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3591128_14 1392489.JPOL01000002_gene655 2.344e-20 99.0 2BD06@1|root,326MC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3594533_0 234267.Acid_6656 4.396e-41 171.0 COG1228@1|root,COG1228@2|Bacteria,3Y32S@57723|Acidobacteria 57723|Acidobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD1_k127_3595429_2 1123504.JQKD01000024_gene296 2.41e-63 224.0 COG3181@1|root,COG3181@2|Bacteria,1NRQH@1224|Proteobacteria,2VZRJ@28216|Betaproteobacteria,4AGEG@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_3595429_4 312153.Pnuc_1720 3.11e-14 78.0 29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VT23@28216|Betaproteobacteria,1K7H6@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD1_k127_3595429_0 1144310.PMI07_005257 8.279e-158 511.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,4BBBH@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD1_k127_3595429_3 795797.C497_17047 5.912e-52 196.0 COG2141@1|root,arCOG02410@2157|Archaea,2XT6F@28890|Euryarchaeota,23TX5@183963|Halobacteria 183963|Halobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_3595429_1 1089553.Tph_c23930 6.462e-136 446.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42HS5@68295|Thermoanaerobacterales 186801|Clostridia H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ubiD - - ko:K16874 ko00365,ko01120,map00365,map01120 - R10213 RC03086 ko00000,ko00001 - - - UbiD DYD1_k127_3598078_2 926569.ANT_07480 1.501e-14 83.0 COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi 200795|Chloroflexi P PFAM NMT1 THI5 like domain protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_3598078_1 479435.Kfla_3151 2.718e-26 112.0 COG3871@1|root,COG3871@2|Bacteria,2I2S9@201174|Actinobacteria,4DQVV@85009|Propionibacteriales 201174|Actinobacteria S Pfam:Pyridox_oxidase - - - - - - - - - - - - Putative_PNPOx DYD1_k127_3598078_0 1089553.Tph_c23930 2.705e-133 439.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42HS5@68295|Thermoanaerobacterales 186801|Clostridia H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ubiD - - ko:K16874 ko00365,ko01120,map00365,map01120 - R10213 RC03086 ko00000,ko00001 - - - UbiD DYD1_k127_3600524_1 861299.J421_4396 2.877e-97 325.0 arCOG09511@1|root,2Z9DH@2|Bacteria 2|Bacteria S FRG - - - - - - - - - - - - FRG DYD1_k127_3600524_3 452662.SJA_C1-02370 1.159e-34 143.0 COG1024@1|root,COG1024@2|Bacteria,1MVB1@1224|Proteobacteria,2TVK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA ech - 4.1.2.41,4.2.1.101 ko:K18383 ko00360,ko01100,ko01110,map00360,map01100,map01110 - R05772,R05773 RC00307,RC01468,RC01828 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_3600524_0 1206731.BAGB01000023_gene1256 2.465e-98 352.0 COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4FW1X@85025|Nocardiaceae 201174|Actinobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_3600524_2 1231391.AMZF01000046_gene961 1.094e-43 173.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_3604311_2 398527.Bphyt_1487 5.784e-26 113.0 COG0346@1|root,COG0346@2|Bacteria,1QVY4@1224|Proteobacteria,2VY37@28216|Betaproteobacteria,1K58Q@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase DYD1_k127_3604311_3 671143.DAMO_1166 1.749e-05 48.0 COG1622@1|root,COG1622@2|Bacteria,2NNSH@2323|unclassified Bacteria 2|Bacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C DYD1_k127_3604311_1 671143.DAMO_1166 3.64e-72 248.0 COG1622@1|root,COG1622@2|Bacteria,2NNSH@2323|unclassified Bacteria 2|Bacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxM GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C DYD1_k127_3604311_0 671143.DAMO_1165 4.277e-166 531.0 COG0843@1|root,COG0843@2|Bacteria,2NNTQ@2323|unclassified Bacteria 2|Bacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B coxN GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 DYD1_k127_3614589_11 1123371.ATXH01000005_gene2098 1.619e-20 99.0 COG1355@1|root,COG1355@2|Bacteria,2GGS5@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Memo-like protein - - - ko:K06990 - - - - ko00000,ko04812 - - - Memo DYD1_k127_3614589_9 1379698.RBG1_1C00001G0339 1.33e-37 143.0 COG2151@1|root,COG2151@2|Bacteria,2NPUI@2323|unclassified Bacteria 2|Bacteria S Pfam:DUF59 paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P DYD1_k127_3614589_3 378806.STAUR_4353 1.195e-119 395.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales 28221|Deltaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA DYD1_k127_3614589_10 926556.Echvi_0018 3.222e-28 123.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PDZ@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,OmpA,PD40 DYD1_k127_3614589_8 269799.Gmet_3020 1.218e-52 192.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WMZE@28221|Deltaproteobacteria,43UMJ@69541|Desulfuromonadales 28221|Deltaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf DYD1_k127_3614589_4 1120972.AUMH01000002_gene2761 2.404e-119 393.0 2C1EV@1|root,33RW1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Cupin_2 DYD1_k127_3614589_12 909663.KI867150_gene1131 1.001e-16 82.0 COG4770@1|root,COG4770@2|Bacteria,1Q2C7@1224|Proteobacteria,437YM@68525|delta/epsilon subdivisions,2X9S9@28221|Deltaproteobacteria,2MSE4@213462|Syntrophobacterales 28221|Deltaproteobacteria I Glycine cleavage H-protein - - - - - - - - - - - - Biotin_lipoyl DYD1_k127_3614589_2 335543.Sfum_3585 8.019e-162 517.0 COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MQ5Q@213462|Syntrophobacterales 28221|Deltaproteobacteria C Na+-transporting oxaloacetate decarboxylase beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta DYD1_k127_3614589_1 332101.JIBU02000032_gene3045 2.33e-173 557.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,36E1X@31979|Clostridiaceae 186801|Clostridia I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yqjD - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD1_k127_3614589_7 56110.Oscil6304_5452 8.073e-65 242.0 COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HABM@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg DYD1_k127_3614589_6 215803.DB30_6335 3.225e-66 228.0 COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales 28221|Deltaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_3614589_5 1242864.D187_002316 5.357e-111 400.0 COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43C1G@68525|delta/epsilon subdivisions,2X7C4@28221|Deltaproteobacteria,2Z3F9@29|Myxococcales 28221|Deltaproteobacteria T PAS fold - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4 DYD1_k127_3614589_13 519989.ECTPHS_13617 1.135e-07 56.0 COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Excisionase - - - - - - - - - - - - HTH_17 DYD1_k127_3614589_0 429009.Adeg_0920 2.165e-204 654.0 COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,42FES@68295|Thermoanaerobacterales 186801|Clostridia HP TIGRFAM molybdenum cofactor synthesis - - 2.10.1.1 ko:K03750,ko:K07219 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N,PBP_like DYD1_k127_3642670_0 330214.NIDE0310 3.875e-103 357.0 COG1053@1|root,COG1053@2|Bacteria,3J0ZM@40117|Nitrospirae 40117|Nitrospirae C Fumarate reductase flavoprotein C-term - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_3642670_1 1485545.JQLW01000005_gene1050 1.77e-35 139.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria 1224|Proteobacteria C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes lpdA-3 - 1.16.1.1 ko:K00520 - - - - ko00000,ko01000 - - - HMA,Pyr_redox_2,Pyr_redox_dim DYD1_k127_3646073_3 330214.NIDE4233 8.835e-33 133.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - ko:K14059 - - - - ko00000 - - - Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase DYD1_k127_3646073_5 1267005.KB911255_gene2387 1.097e-07 53.0 COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom DYD1_k127_3646073_4 1231391.AMZF01000046_gene961 4.091e-24 115.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_3646073_1 1231391.AMZF01000063_gene1102 1.052e-94 332.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_3646073_2 593117.TGAM_1014 7.983e-86 297.0 COG3839@1|root,arCOG00175@2157|Archaea,2Y7MB@28890|Euryarchaeota 28890|Euryarchaeota E PFAM ABC transporter - - 3.6.3.29,3.6.3.30 ko:K02010,ko:K02017,ko:K02062,ko:K10112,ko:K10199,ko:K17314 ko02010,map02010 M00189,M00190,M00191,M00194,M00196,M00197,M00200,M00201,M00203,M00206,M00207,M00491,M00602,M00604,M00605,M00606 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.13,3.A.1.1.14,3.A.1.1.15,3.A.1.10,3.A.1.19,3.A.1.8 - - ABC_tran,TOBE_2 DYD1_k127_3646073_0 1210884.HG799464_gene10982 2.863e-162 524.0 COG1236@1|root,COG1236@2|Bacteria,2IXNS@203682|Planctomycetes 203682|Planctomycetes J Exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL DYD1_k127_3651765_1 640081.Dsui_1467 7.677e-107 358.0 COG4591@1|root,COG4591@2|Bacteria,1QVRH@1224|Proteobacteria 1224|Proteobacteria M COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_3651765_0 1379698.RBG1_1C00001G1667 3.23e-111 371.0 COG0577@1|root,COG0577@2|Bacteria,2NQPT@2323|unclassified Bacteria 2|Bacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_3651765_3 1379698.RBG1_1C00001G1666 9.859e-100 329.0 COG1136@1|root,COG1136@2|Bacteria,2NPA8@2323|unclassified Bacteria 2|Bacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_3651765_2 1379698.RBG1_1C00001G1665 6.269e-104 351.0 COG0845@1|root,COG0845@2|Bacteria,2NQ2U@2323|unclassified Bacteria 2|Bacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion acrA - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_3651765_4 195253.Syn6312_0370 6.884e-82 280.0 COG4106@1|root,COG4106@2|Bacteria,1G3BF@1117|Cyanobacteria,1H37T@1129|Synechococcus 1117|Cyanobacteria S Methyltransferase domain - - 2.1.1.144 ko:K00598 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 DYD1_k127_3651765_6 330214.NIDE1495 8.199e-37 141.0 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif rbpA - - - - - - - - - - - RRM_1 DYD1_k127_3651765_9 123899.JPQP01000004_gene678 8.993e-16 81.0 COG1917@1|root,COG1917@2|Bacteria,1RJBF@1224|Proteobacteria,2W48U@28216|Betaproteobacteria 28216|Betaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - DYD1_k127_3651765_8 446462.Amir_4888 3.34e-17 93.0 COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria,4E27N@85010|Pseudonocardiales 201174|Actinobacteria P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_3651765_7 1122212.AULO01000013_gene2037 2.9e-31 134.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1RPSX@1236|Gammaproteobacteria,1XI3E@135619|Oceanospirillales 135619|Oceanospirillales I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692,ko:K16880 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00365,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00365,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10210 RC00004,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC01903,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD1_k127_3651765_5 1382303.JPOM01000001_gene43 4.632e-37 152.0 COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - - - - - - - - - - - ECH_1 DYD1_k127_3663573_6 316067.Geob_3656 1.129e-09 63.0 COG3809@1|root,COG3809@2|Bacteria 2|Bacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - Rhomboid,zf-TFIIB DYD1_k127_3663573_4 671143.DAMO_0988 1.512e-30 126.0 COG1499@1|root,COG1499@2|Bacteria,2NS26@2323|unclassified Bacteria 2|Bacteria J ribosomal large subunit export from nucleus - - - - - - - - - - - - NMD3 DYD1_k127_3663573_1 909663.KI867150_gene69 7.381e-77 262.0 arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3663573_2 247490.KSU1_D0846 1.379e-56 203.0 2B5RU@1|root,31YMF@2|Bacteria,2J42A@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - DYD1_k127_3663573_3 330214.NIDE3490 7.383e-49 179.0 COG5592@1|root,COG5592@2|Bacteria 2|Bacteria I hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin,Phasin_2 DYD1_k127_3663573_5 945713.IALB_1656 1.16e-27 116.0 COG0599@1|root,COG0599@2|Bacteria 2|Bacteria S peroxiredoxin activity - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD DYD1_k127_3663573_0 215803.DB30_4199 1.596e-278 875.0 COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria,2YWJW@29|Myxococcales 28221|Deltaproteobacteria P Cytochrome C and Quinol oxidase polypeptide I norZ - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 DYD1_k127_3676665_0 706587.Desti_0365 1.585e-49 198.0 COG2114@1|root,COG2114@2|Bacteria 2|Bacteria T Pfam Adenylate and Guanylate cyclase catalytic domain cyaD - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - FHA,Fer2,GAF,GAF_2,Guanylate_cyc,Pkinase,Response_reg DYD1_k127_3676665_1 748247.AZKH_0922 5.739e-18 98.0 COG2199@1|root,COG5000@1|root,COG3706@2|Bacteria,COG5000@2|Bacteria,1MZV7@1224|Proteobacteria,2WI0C@28216|Betaproteobacteria,2KZVF@206389|Rhodocyclales 206389|Rhodocyclales T diguanylate cyclase - - - - - - - - - - - - GGDEF,HAMP,PAS DYD1_k127_3676665_2 426117.M446_6721 1.039e-08 63.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,1JUDJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_3683048_0 189753.AXAS01000041_gene2534 3.592e-89 304.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_3683048_2 202955.BBND01000006_gene2869 3.68e-33 134.0 29D2D@1|root,3000G@2|Bacteria,1P3UF@1224|Proteobacteria,1RT5D@1236|Gammaproteobacteria,3NS99@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3683048_1 443152.MDG893_15295 2.587e-46 178.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_368730_1 443598.AUFA01000009_gene5633 0.0001668 44.0 COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria,3JQR6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O methyltransferase activity - - 2.1.1.334 ko:K21310 ko00920,map00920 - R11546 RC02653 ko00000,ko00001,ko01000 - - - NnrU,PEMT DYD1_k127_368730_0 706587.Desti_5142 1.173e-32 137.0 COG1102@1|root,COG1102@2|Bacteria,1R82J@1224|Proteobacteria,42M5Z@68525|delta/epsilon subdivisions,2WMEJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Cytidylate kinase-like family - - - - - - - - - - - - Cytidylate_kin2 DYD1_k127_370190_5 1173263.Syn7502_03004 1.745e-17 94.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_370190_0 289377.HL41_03360 3.379e-148 479.0 COG0475@1|root,COG0475@2|Bacteria 2|Bacteria P glutathione-regulated potassium exporter activity - - - - - - - - - - - - Na_H_Exchanger DYD1_k127_370190_3 289377.HL41_03355 4.039e-32 130.0 COG0589@1|root,COG0589@2|Bacteria,2GI5H@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria T Universal stress protein family - - - - - - - - - - - - Usp DYD1_k127_370190_4 1122194.AUHU01000003_gene2147 8.699e-24 106.0 COG0385@1|root,COG0385@2|Bacteria,1MXPA@1224|Proteobacteria,1RY4B@1236|Gammaproteobacteria,464V3@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bile acid sodium symporter - - - - - - - - - - - - SBF DYD1_k127_370190_6 333138.LQ50_18820 3.558e-15 78.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus 91061|Bacilli CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c resA GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - - - - - - - - - - AhpC-TSA DYD1_k127_370190_8 694427.Palpr_1933 0.0006436 46.0 COG0526@1|root,COG0526@2|Bacteria,4NNMK@976|Bacteroidetes,2FQ45@200643|Bacteroidia,22XXA@171551|Porphyromonadaceae 976|Bacteroidetes CO Thioredoxin - - - - - - - - - - - - AhpC-TSA,Redoxin DYD1_k127_370190_1 1227739.Hsw_4060 1.891e-144 467.0 COG0659@1|root,COG0659@2|Bacteria 2|Bacteria P secondary active sulfate transmembrane transporter activity - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - MFS_MOT1 DYD1_k127_370190_2 179408.Osc7112_2604 7.934e-132 428.0 COG1397@1|root,COG1397@2|Bacteria,1G30S@1117|Cyanobacteria,1HD71@1150|Oscillatoriales 1117|Cyanobacteria O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH DYD1_k127_370190_7 237368.SCABRO_02452 5.005e-13 71.0 COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes 203682|Planctomycetes T Universal stress protein - - - - - - - - - - - - Usp DYD1_k127_373913_1 1463857.JOFZ01000001_gene5316 9.902e-47 177.0 COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria 201174|Actinobacteria E ornithine cyclodeaminase ocd - 1.4.1.1,4.3.1.12 ko:K01750,ko:K19244 ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230 - R00396,R00671 RC00008,RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_373913_0 443152.MDG893_15040 1.474e-98 333.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria 1224|Proteobacteria E ornithine cyclodeaminase - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_376709_16 522306.CAP2UW1_0658 1.911e-39 160.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2WFNY@28216|Betaproteobacteria,1KR5H@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_376709_9 1089553.Tph_c03540 8.11e-83 283.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,42EYJ@68295|Thermoanaerobacterales 186801|Clostridia P ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N DYD1_k127_376709_4 1499967.BAYZ01000076_gene838 2.938e-107 356.0 COG0601@1|root,COG0601@2|Bacteria 2|Bacteria P nitrogen compound transport - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD1_k127_376709_2 1499967.BAYZ01000028_gene1281 1.845e-136 452.0 COG0747@1|root,COG0747@2|Bacteria,2NR54@2323|unclassified Bacteria 2|Bacteria E Bacterial extracellular solute-binding proteins, family 5 Middle appA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_376709_11 1232410.KI421412_gene412 5.435e-68 240.0 COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales 28221|Deltaproteobacteria O Cytochrome C assembly protein - - - - - - - - - - - - Cytochrom_C_asm DYD1_k127_376709_3 1232410.KI421412_gene411 1.676e-129 430.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH DYD1_k127_376709_7 1304885.AUEY01000013_gene3121 2.308e-86 296.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2MISN@213118|Desulfobacterales 28221|Deltaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC DYD1_k127_376709_10 266117.Rxyl_1977 1.76e-68 242.0 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria 84995|Rubrobacteria H Belongs to the precorrin methyltransferase family - - 2.1.1.107,4.2.1.75 ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4,TP_methylase DYD1_k127_376709_1 1125863.JAFN01000001_gene3397 4.125e-142 458.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD DYD1_k127_376709_17 443144.GM21_0541 2.036e-09 61.0 28T91@1|root,2ZFHN@2|Bacteria,1P659@1224|Proteobacteria,433I9@68525|delta/epsilon subdivisions,2WX6G@28221|Deltaproteobacteria,43VY2@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_376709_18 1218076.BAYB01000027_gene4574 2.297e-09 63.0 2CIZN@1|root,33BAP@2|Bacteria,1NJHF@1224|Proteobacteria,2WD0R@28216|Betaproteobacteria,1K8YN@119060|Burkholderiaceae 28216|Betaproteobacteria S Superinfection immunity protein - - - - - - - - - - - - Imm_superinfect DYD1_k127_376709_14 1125863.JAFN01000001_gene577 5.517e-47 190.0 COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA DYD1_k127_376709_12 330214.NIDE0251 1.095e-57 212.0 COG2071@1|root,COG2071@2|Bacteria,3J0PV@40117|Nitrospirae 40117|Nitrospirae S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 DYD1_k127_376709_13 1499967.BAYZ01000147_gene728 4.734e-57 223.0 COG0741@1|root,COG4105@1|root,COG0741@2|Bacteria,COG4105@2|Bacteria,2NPKN@2323|unclassified Bacteria 2|Bacteria M Transglycosylase SLT domain slt - - ko:K06381,ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,TPR_16,TPR_6,TPR_8 DYD1_k127_376709_15 644966.Tmar_1759 1.083e-40 156.0 COG3427@1|root,COG3427@2|Bacteria,1VA2M@1239|Firmicutes,254US@186801|Clostridia 186801|Clostridia S Carbon monoxide dehydrogenase subunit G (CoxG) - - - ko:K09386 - - - - ko00000 - - - COXG DYD1_k127_376709_8 880072.Desac_0368 3.935e-86 295.0 COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2WJYJ@28221|Deltaproteobacteria,2MQV7@213462|Syntrophobacterales 28221|Deltaproteobacteria S PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_376709_19 1499967.BAYZ01000061_gene5953 3.848e-07 59.0 COG1475@1|root,COG1475@2|Bacteria,2NRF2@2323|unclassified Bacteria 2|Bacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc DYD1_k127_376709_5 1499967.BAYZ01000061_gene5954 8.806e-105 352.0 COG1533@1|root,COG1533@2|Bacteria,2NPZ9@2323|unclassified Bacteria 2|Bacteria L DNA photolyase activity - - 4.1.99.14 ko:K03716 - - - - ko00000,ko01000 - - - Radical_SAM DYD1_k127_376709_6 243231.GSU2923 1.507e-94 317.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales 28221|Deltaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - iAF987.Gmet_0547 Asp_Glu_race DYD1_k127_376709_0 330214.NIDE0623 1.251e-289 927.0 COG0653@1|root,COG0653@2|Bacteria,3J0E5@40117|Nitrospirae 40117|Nitrospirae U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD1_k127_3773469_0 649638.Trad_0897 5.133e-262 819.0 COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C dehydrogenase e1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr DYD1_k127_3773469_2 300852.55771670 1.368e-128 422.0 COG0508@1|root,COG0508@2|Bacteria,1WIIU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_3773469_4 1128421.JAGA01000003_gene2880 1.436e-21 100.0 2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria 2|Bacteria S Prokaryotic Cytochrome C oxidase subunit IV - - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - COX4_pro DYD1_k127_3773469_3 472759.Nhal_2611 8.514e-73 251.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1X2EW@135613|Chromatiales 135613|Chromatiales C Cytochrome c oxidase subunit III - - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 DYD1_k127_3773469_1 234267.Acid_0498 2.534e-203 637.0 COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria 57723|Acidobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 DYD1_k127_3798589_4 1537715.JQFJ01000002_gene883 1.029e-177 567.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,2K0WS@204457|Sphingomonadales 204457|Sphingomonadales P Rieske (2Fe-2S) domain-containing protein ligX - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_3798589_9 999611.KI421505_gene4130 3.285e-48 184.0 COG3221@1|root,COG3221@2|Bacteria,1RKVE@1224|Proteobacteria,2V2DJ@28211|Alphaproteobacteria,2829W@191028|Leisingera 28211|Alphaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - - - - - - - - - - Phosphonate-bd DYD1_k127_3798589_7 1265313.HRUBRA_01049 2.056e-72 254.0 COG2850@1|root,COG2850@2|Bacteria,1RDTN@1224|Proteobacteria,1SDPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cupin-like domain - - - - - - - - - - - - Cupin_8 DYD1_k127_3798589_8 1537994.JQFW01000001_gene3530 4.678e-53 198.0 COG2267@1|root,COG2267@2|Bacteria,1R79U@1224|Proteobacteria,1S3DE@1236|Gammaproteobacteria,469I6@72275|Alteromonadaceae 1236|Gammaproteobacteria I Serine aminopeptidase, S33 phaG - - ko:K18100 ko02024,ko02025,map02024,map02025 - - - ko00000,ko00001,ko01000,ko01003 - GT1 - Abhydrolase_1,Hydrolase_4 DYD1_k127_3798589_1 211165.AJLN01000093_gene1049 0.0 1194.0 COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae 1117|Cyanobacteria G Carbohydrate phosphorylase glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase DYD1_k127_3798589_2 1108045.GORHZ_053_00330 0.0 1012.0 COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4GBC7@85026|Gordoniaceae 201174|Actinobacteria G Carbohydrate-binding module 48 (Isoamylase N-terminal domain) glgX - 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 DYD1_k127_3798589_3 330214.NIDE2083 1.95e-257 806.0 COG0033@1|root,COG0033@2|Bacteria,3J1FS@40117|Nitrospirae 40117|Nitrospirae G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_3798589_6 366394.Smed_2994 7.423e-85 286.0 COG0406@1|root,COG0406@2|Bacteria,1RCJE@1224|Proteobacteria,2U6UK@28211|Alphaproteobacteria,4BB31@82115|Rhizobiaceae 28211|Alphaproteobacteria G Phosphoglycerate mutase gpmB1 - - - - - - - - - - - His_Phos_1 DYD1_k127_3798589_5 1144275.COCOR_01449 1.154e-145 468.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,42NZZ@68525|delta/epsilon subdivisions,2WM6K@28221|Deltaproteobacteria 28221|Deltaproteobacteria G Fructose-bisphosphate aldolase class-I - - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic DYD1_k127_3798589_0 1169143.KB911035_gene2454 0.0 1398.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,1K1A2@119060|Burkholderiaceae 28216|Betaproteobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N DYD1_k127_3803825_1 314278.NB231_07462 2.149e-131 423.0 COG2230@1|root,COG2230@2|Bacteria,1QY55@1224|Proteobacteria,1RYEN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Putative methyltransferase - - - - - - - - - - - - Methyltransf_31 DYD1_k127_3803825_4 1231391.AMZF01000007_gene1472 3.27e-111 367.0 COG1028@1|root,COG1028@2|Bacteria,1MU3W@1224|Proteobacteria,2WF8J@28216|Betaproteobacteria,3T9D4@506|Alcaligenaceae 28216|Betaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 DYD1_k127_3803825_14 491205.JARQ01000008_gene3843 2.742e-23 102.0 2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,1I2SM@117743|Flavobacteriia,3ZS72@59732|Chryseobacterium 976|Bacteroidetes S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_3803825_15 935840.JAEQ01000004_gene646 9.083e-15 86.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_3803825_12 985053.VMUT_1247 2.236e-31 136.0 COG0451@1|root,arCOG04468@2157|Archaea 2157|Archaea M epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd DYD1_k127_3803825_9 1231391.AMZF01000020_gene1928 9.508e-36 149.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_3803825_10 1231391.AMZF01000069_gene2126 1.049e-32 141.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_3803825_8 1231391.AMZF01000008_gene1529 3.137e-39 159.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_3803825_0 1231391.AMZF01000063_gene1102 1.356e-158 518.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_3803825_3 561175.KB894105_gene943 6.588e-114 377.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EFFE@85012|Streptosporangiales 201174|Actinobacteria E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 DYD1_k127_3803825_7 1128421.JAGA01000002_gene84 2.116e-40 156.0 COG2068@1|root,COG2068@2|Bacteria,2NPK5@2323|unclassified Bacteria 2|Bacteria S 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD1_k127_3803825_5 1500257.JQNM01000014_gene2912 1.558e-85 293.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,4BCDD@82115|Rhizobiaceae 28211|Alphaproteobacteria P 4,5-dihydroxyphthalate decarboxylase - - - - - - - - - - - - NMT1 DYD1_k127_3803825_2 671143.DAMO_2787 1.937e-121 400.0 COG0301@1|root,COG0301@2|Bacteria,2NPBT@2323|unclassified Bacteria 2|Bacteria H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307 THUMP,ThiI DYD1_k127_3803825_11 42256.RradSPS_2277 2.696e-32 128.0 COG0662@1|root,COG0662@2|Bacteria,2GXJK@201174|Actinobacteria 201174|Actinobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_3803825_13 373994.Riv7116_4552 1.222e-30 126.0 COG4319@1|root,COG4319@2|Bacteria,1G6QY@1117|Cyanobacteria,1HP5H@1161|Nostocales 1117|Cyanobacteria S Calcium/calmodulin dependent protein kinase II association domain - - - - - - - - - - - - SnoaL_3 DYD1_k127_3803825_6 526227.Mesil_1171 1.525e-50 188.0 COG4221@1|root,COG4221@2|Bacteria,1WIDQ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD1_k127_3808524_1 1131814.JAFO01000001_gene1871 4.021e-22 107.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria 1224|Proteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2,TAT_signal DYD1_k127_3808524_0 489825.LYNGBM3L_54460 1.169e-46 180.0 COG3221@1|root,COG3221@2|Bacteria,1G2AZ@1117|Cyanobacteria,1HAC9@1150|Oscillatoriales 1117|Cyanobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd DYD1_k127_3809448_5 1121091.AUMP01000023_gene3851 6.217e-10 67.0 2E17N@1|root,32WNB@2|Bacteria,1VDC9@1239|Firmicutes,4HHCQ@91061|Bacilli 91061|Bacilli S SMI1-KNR4 cell-wall - - - ko:K21488 - - - - ko00000,ko02048 - - - SUKH_5 DYD1_k127_3809448_1 2340.JV46_20180 1.115e-52 192.0 2C8PG@1|root,32RMK@2|Bacteria,1N0UQ@1224|Proteobacteria,1SBBP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_3809448_2 493475.GARC_1083 3.47e-49 179.0 COG0454@1|root,COG0456@2|Bacteria,1PT7Z@1224|Proteobacteria,1SBDF@1236|Gammaproteobacteria,4699Z@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acetyltransferase (GNAT) domain - - - ko:K03830 - - - - ko00000,ko01000 - - - Acetyltransf_10 DYD1_k127_3809448_4 1227454.C446_02607 6.979e-25 115.0 COG0697@1|root,arCOG00272@2157|Archaea,2XVSM@28890|Euryarchaeota,23S7J@183963|Halobacteria 183963|Halobacteria G COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD1_k127_3809448_0 857087.Metme_1420 0.0 1293.0 COG2373@1|root,COG2373@2|Bacteria,1Q2SN@1224|Proteobacteria,1S1CA@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Animal haem peroxidase - - - - - - - - - - - - An_peroxidase DYD1_k127_3809448_3 886293.Sinac_4454 2.933e-37 150.0 COG0642@1|root,COG0745@1|root,COG2203@1|root,COG3829@1|root,COG3852@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,2IX8Z@203682|Planctomycetes 203682|Planctomycetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,Response_reg DYD1_k127_3809448_6 859657.RPSI07_mp1212 1.681e-05 50.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,1JZSA@119060|Burkholderiaceae 28216|Betaproteobacteria T catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - - - - - - - - - - DUF4118,GerE,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,Response_reg DYD1_k127_3817611_5 530564.Psta_4013 5.882e-08 61.0 COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes 203682|Planctomycetes T FHA domain - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - FHA,GAF_2,SpoIIE DYD1_k127_3817611_0 1120949.KB903314_gene304 2.213e-81 284.0 2C1EV@1|root,33RW1@2|Bacteria,2ICZG@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_3817611_4 1532558.JL39_06940 1.23e-19 102.0 COG1840@1|root,COG1840@2|Bacteria,1PGNJ@1224|Proteobacteria,2V7JA@28211|Alphaproteobacteria,4BDDZ@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 DYD1_k127_3817611_3 443152.MDG893_15295 2.531e-47 183.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_3817611_1 797299.HALLA_02515 3.345e-77 272.0 COG4948@1|root,arCOG01168@2157|Archaea,2XUAS@28890|Euryarchaeota,23SVB@183963|Halobacteria 183963|Halobacteria M COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD1_k127_3817611_6 864702.OsccyDRAFT_3825 0.0005476 51.0 COG0457@1|root,COG0457@2|Bacteria,1G420@1117|Cyanobacteria,1H9RD@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_8 DYD1_k127_3817611_2 479434.Sthe_2205 7.224e-52 201.0 COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia 2|Bacteria P Major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_3818852_1 1173027.Mic7113_5684 5.72e-69 256.0 COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,1G48R@1117|Cyanobacteria 1117|Cyanobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg DYD1_k127_3818852_2 63737.Npun_F3676 1.564e-68 235.0 COG0745@1|root,COG0745@2|Bacteria,1G79X@1117|Cyanobacteria,1HS8I@1161|Nostocales 1117|Cyanobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_3818852_0 1123368.AUIS01000004_gene120 5.276e-103 353.0 COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria,2NDJ6@225057|Acidithiobacillales 1236|Gammaproteobacteria T PAS fold - - - - - - - - - - - - DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd DYD1_k127_3827083_1 1379698.RBG1_1C00001G0856 9.491e-91 304.0 COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S dicluster domain - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7 DYD1_k127_3827083_0 1379698.RBG1_1C00001G0855 4.499e-172 569.0 COG0243@1|root,COG0243@2|Bacteria,2NPRJ@2323|unclassified Bacteria 2|Bacteria C Molydopterin dinucleotide binding domain qrcB - 1.8.5.5 ko:K08352 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_3827083_2 926569.ANT_24800 1.397e-28 122.0 COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi 200795|Chloroflexi C Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrome_C7 DYD1_k127_3829214_0 314287.GB2207_06688 7.595e-165 529.0 COG1703@1|root,COG1884@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1J8QV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase DYD1_k127_3829214_3 237368.SCABRO_00545 4.063e-19 91.0 COG4634@1|root,COG4634@2|Bacteria,2J4DQ@203682|Planctomycetes 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_3829214_2 518766.Rmar_0293 1.714e-24 104.0 COG2442@1|root,COG2442@2|Bacteria,4NX9P@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 DYD1_k127_3829214_4 357808.RoseRS_2516 6.516e-07 51.0 COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,377RE@32061|Chloroflexia 32061|Chloroflexia H PFAM Methionine synthase, vitamin-B12 independent - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_3829214_1 1254432.SCE1572_27170 3.388e-86 304.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales 28221|Deltaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_3850701_4 1144310.PMI07_005585 4.093e-28 126.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_3850701_1 1304878.AUGD01000025_gene3859 5.955e-65 235.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,3JRGD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14,4.4.1.23 ko:K00549,ko:K22363 ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230 M00017 R04405,R09365,R11897,R11899 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_3850701_2 710686.Mycsm_01832 9.34e-48 185.0 COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria 201174|Actinobacteria S NMT1-like family - - - - - - - - - - - - NMT1_3 DYD1_k127_3850701_3 215803.DB30_0689 1.885e-34 143.0 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WIMQ@28221|Deltaproteobacteria,2YYKM@29|Myxococcales 28221|Deltaproteobacteria S Calcineurin-like phosphoesterase - - - ko:K07098 - - - - ko00000 - - - CarS-like,Metallophos DYD1_k127_3850701_0 1192034.CAP_6251 2.965e-103 347.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_3857532_4 1307761.L21SP2_0672 5.399e-13 74.0 COG0399@1|root,COG0399@2|Bacteria 2|Bacteria E UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1,Y2_Tnp,Zn_Tnp_IS91 DYD1_k127_3857532_2 330214.NIDE3688 5.552e-17 83.0 COG2161@1|root,COG2161@2|Bacteria 2|Bacteria D toxin-antitoxin pair type II binding relF GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 ko:K08591,ko:K19159 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko02048 - - - PhdYeFM_antitox DYD1_k127_3857532_3 671143.DAMO_2686 2.006e-14 78.0 COG2026@1|root,COG2026@2|Bacteria 2|Bacteria DJ nuclease activity relE GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin DYD1_k127_3857532_1 1111479.AXAR01000006_gene733 6.58e-62 216.0 COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,4HINQ@91061|Bacilli 91061|Bacilli C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_3857532_0 1380356.JNIK01000013_gene4111 1.621e-72 257.0 COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4EU5S@85013|Frankiales 201174|Actinobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3,1.5.99.4 ko:K03520,ko:K19820 ko00760,ko01120,map00760,map01120 M00810 R02860,R07946,R11168 RC00589,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_3864334_0 76114.ebA1984 4.266e-82 276.0 COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,2VIYW@28216|Betaproteobacteria 28216|Betaproteobacteria O Glutathione S-transferase gstP - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_3 DYD1_k127_3864334_2 331869.BAL199_27875 4.63e-06 57.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - PG_binding_1 DYD1_k127_3864334_1 345341.KUTG_08561 9.022e-11 66.0 COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria,4E4EM@85010|Pseudonocardiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_3871278_9 1043493.BBLU01000017_gene1379 1.039e-64 228.0 COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria 201174|Actinobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD DYD1_k127_3871278_4 671143.DAMO_2186 2.06e-167 538.0 COG0148@1|root,COG0148@2|Bacteria,2NNKW@2323|unclassified Bacteria 2|Bacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N DYD1_k127_3871278_19 398767.Glov_1139 2.801e-08 60.0 COG2919@1|root,COG2919@2|Bacteria,1NM5U@1224|Proteobacteria,42X2K@68525|delta/epsilon subdivisions,2WSPM@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic divIC - - ko:K05589,ko:K13052 - - - - ko00000,ko03036 - - - DivIC DYD1_k127_3871278_8 240016.ABIZ01000001_gene4696 6.332e-68 239.0 COG2518@1|root,COG2518@2|Bacteria,46V8Z@74201|Verrucomicrobia,2IUUY@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - PCMT DYD1_k127_3871278_12 1405498.SSIM_05225 2.057e-35 140.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,4GZ53@90964|Staphylococcaceae 91061|Bacilli E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H DYD1_k127_3871278_17 406327.Mevan_1399 4.204e-27 117.0 COG4032@1|root,arCOG01613@2157|Archaea,2XYBY@28890|Euryarchaeota,23QS9@183939|Methanococci 183939|Methanococci S Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019295,GO:0019296,GO:0044237,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0050545,GO:0051186,GO:0051188,GO:0071704,GO:1901576 4.1.1.79 ko:K06034 ko00680,ko01120,map00680,map01120 M00358 R05774 RC00506 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_N DYD1_k127_3871278_14 388467.A19Y_2947 3.639e-30 126.0 COG0028@1|root,COG4032@1|root,COG0028@2|Bacteria,COG4032@2|Bacteria,1G36U@1117|Cyanobacteria,1HFJ5@1150|Oscillatoriales 1117|Cyanobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 4.1.1.82 ko:K09459 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R04053 RC00506 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_N DYD1_k127_3871278_18 335543.Sfum_0376 4.187e-25 119.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria,2MQIP@213462|Syntrophobacterales 28221|Deltaproteobacteria M Bacterial lipid A biosynthesis acyltransferase htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD1_k127_3871278_15 404589.Anae109_1277 5.54e-30 125.0 COG1959@1|root,COG1959@2|Bacteria,1Q19C@1224|Proteobacteria,4375I@68525|delta/epsilon subdivisions,2WRDB@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Rrf2 DYD1_k127_3871278_6 1125863.JAFN01000001_gene2667 6.89e-154 496.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine nifS-1 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 DYD1_k127_3871278_2 671143.DAMO_2383 4.017e-282 870.0 COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria 2|Bacteria O FeS assembly protein SufB sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - ko:K07033,ko:K09014 - - - - ko00000 - - iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 UPF0051 DYD1_k127_3871278_13 1201290.M902_1586 2.96e-31 125.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,43ADA@68525|delta/epsilon subdivisions,2MUSB@213481|Bdellovibrionales,2X5SP@28221|Deltaproteobacteria 213481|Bdellovibrionales S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn DYD1_k127_3871278_3 1210884.HG799464_gene11188 3.601e-172 549.0 COG1104@1|root,COG1104@2|Bacteria,2IXJC@203682|Planctomycetes 203682|Planctomycetes E COG1104 Cysteine sulfinate desulfinase cysteine desulfurase - - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 DYD1_k127_3871278_0 1232410.KI421422_gene2090 5.63e-321 1003.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,43SBD@69541|Desulfuromonadales 28221|Deltaproteobacteria L ABC transporter uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD1_k127_3871278_5 1123371.ATXH01000009_gene1104 4.5e-162 524.0 COG1109@1|root,COG1109@2|Bacteria,2GHQ7@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_3871278_7 443144.GM21_0061 7.873e-100 336.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,43SZG@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262,1.1.1.408,1.1.1.409 ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA DYD1_k127_3871278_11 404589.Anae109_4481 5.636e-36 153.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,2YVIS@29|Myxococcales 28221|Deltaproteobacteria M SurA N-terminal domain surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3 DYD1_k127_3871278_1 338963.Pcar_0091 5.612e-302 967.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,43SCA@69541|Desulfuromonadales 28221|Deltaproteobacteria L TRCF mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF DYD1_k127_3871278_20 448385.sce3168 3.847e-06 53.0 COG1547@1|root,COG1547@2|Bacteria,1P75K@1224|Proteobacteria,432ZJ@68525|delta/epsilon subdivisions,2WXIJ@28221|Deltaproteobacteria,2Z233@29|Myxococcales 28221|Deltaproteobacteria S Domain of unknown function (DUF309) - - - ko:K09763 - - - - ko00000 - - - DUF309 DYD1_k127_3871278_10 331869.BAL199_24324 1.299e-64 237.0 COG0477@1|root,COG2814@2|Bacteria,1P4XF@1224|Proteobacteria,2U185@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_3871278_16 797209.ZOD2009_17383 1.335e-29 128.0 arCOG12117@1|root,arCOG12117@2157|Archaea,2XXVR@28890|Euryarchaeota,23WGQ@183963|Halobacteria 183963|Halobacteria S Protein of unknown function (DUF3891) - - - - - - - - - - - - DUF3891 DYD1_k127_3877621_0 56780.SYN_02218 0.0 1050.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD1_k127_3877621_6 886293.Sinac_5019 7.678e-22 101.0 COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes 203682|Planctomycetes T Universal stress protein - - - - - - - - - - - - Usp DYD1_k127_3877621_7 290397.Adeh_1425 1.554e-06 55.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c ccoP - - ko:K00406,ko:K08906 ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko00194 3.D.4.3 - - Cytochrome_CBB3,FixP_N DYD1_k127_3877621_5 1379698.RBG1_1C00001G0433 3.295e-22 102.0 COG0701@1|root,COG0701@2|Bacteria,2NQ4Q@2323|unclassified Bacteria 2|Bacteria S Predicted permease MA20_06590 - - ko:K07089 - - - - ko00000 - - - ArsP_1 DYD1_k127_3877621_1 251229.Chro_4996 1.904e-142 462.0 COG1816@1|root,COG1816@2|Bacteria,1G0QF@1117|Cyanobacteria,3VIT2@52604|Pleurocapsales 1117|Cyanobacteria F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism - - 3.5.4.2,3.5.4.4 ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01244,R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase DYD1_k127_3877621_2 1121918.ARWE01000001_gene2162 3.816e-55 198.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,43SGI@69541|Desulfuromonadales 28221|Deltaproteobacteria F Phosphoribosyl transferase domain hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran DYD1_k127_3877621_4 565033.GACE_0099 4.808e-44 173.0 arCOG06549@1|root,arCOG06549@2157|Archaea,2Y31C@28890|Euryarchaeota,246R3@183980|Archaeoglobi 183980|Archaeoglobi C NapC/NirT cytochrome c family, N-terminal region - - - - - - - - - - - - Cytochrom_NNT DYD1_k127_3877621_3 671143.DAMO_0821 4.171e-52 188.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB petB - - ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B DYD1_k127_3886716_27 1304883.KI912532_gene870 0.0002896 45.0 2EAZV@1|root,3350Q@2|Bacteria,1P6NQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_3886716_0 1198452.Jab_2c20790 6.224e-296 931.0 COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,473JF@75682|Oxalobacteraceae 28216|Betaproteobacteria S exporter - - - - - - - - - - - - MMPL DYD1_k127_3886716_15 1005048.CFU_1896 9.699e-73 251.0 COG2834@1|root,COG2834@2|Bacteria,1N9W4@1224|Proteobacteria,2WFUQ@28216|Betaproteobacteria,4748C@75682|Oxalobacteraceae 28216|Betaproteobacteria M Outer membrane lipoprotein carrier protein LolA - - - - - - - - - - - - LolA DYD1_k127_3886716_16 1198452.Jab_2c20810 3.908e-67 231.0 COG0824@1|root,COG0824@2|Bacteria,1RH6W@1224|Proteobacteria,2VSPJ@28216|Betaproteobacteria,474E7@75682|Oxalobacteraceae 28216|Betaproteobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 DYD1_k127_3886716_1 29581.BW37_01682 2.5e-264 825.0 COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2VJB1@28216|Betaproteobacteria,4731V@75682|Oxalobacteraceae 28216|Betaproteobacteria E Aromatic amino acid lyase hutH2 GO:0003674,GO:0003824,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016866,GO:0016869,GO:0050368 4.3.1.23,4.3.1.3 ko:K01745,ko:K10774 ko00340,ko00350,ko01100,map00340,map00350,map01100 M00045 R00737,R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic DYD1_k127_3886716_6 1005048.CFU_1893 3.986e-116 383.0 COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2VHP0@28216|Betaproteobacteria,4735E@75682|Oxalobacteraceae 28216|Betaproteobacteria S Bacterial lipid A biosynthesis acyltransferase - - - - - - - - - - - - Lip_A_acyltrans DYD1_k127_3886716_10 1118235.CAJH01000046_gene2943 7.334e-90 304.0 COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,1T2CN@1236|Gammaproteobacteria,1X4G9@135614|Xanthomonadales 135614|Xanthomonadales S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_3886716_2 1198452.Jab_2c20850 5.593e-184 592.0 COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,2VIYA@28216|Betaproteobacteria,473M1@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C,FabA DYD1_k127_3886716_25 1236542.BALM01000010_gene3740 3.899e-08 57.0 COG4648@1|root,COG4648@2|Bacteria,1N0PK@1224|Proteobacteria,1S9TC@1236|Gammaproteobacteria,2QA7S@267890|Shewanellaceae 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - IspA DYD1_k127_3886716_18 1005048.CFU_1890 3.037e-42 160.0 COG4648@1|root,COG4648@2|Bacteria,1N0PK@1224|Proteobacteria,2VUK9@28216|Betaproteobacteria,474CN@75682|Oxalobacteraceae 28216|Betaproteobacteria S membrane - - - - - - - - - - - - - DYD1_k127_3886716_19 1005048.CFU_1889 3.598e-35 136.0 COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,2VVRR@28216|Betaproteobacteria,4752E@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ Phosphopantetheine attachment site acpM - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD1_k127_3886716_21 1005048.CFU_1888 4.215e-31 126.0 COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,2VWKA@28216|Betaproteobacteria,474SX@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ acyl carrier protein - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD1_k127_3886716_9 1005048.CFU_1887 8.415e-97 323.0 COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,2VNX6@28216|Betaproteobacteria,47241@75682|Oxalobacteraceae 28216|Betaproteobacteria I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase DYD1_k127_3886716_20 391735.Veis_1316 2.333e-32 135.0 2DNSX@1|root,32YZ0@2|Bacteria,1NDSG@1224|Proteobacteria,2WGKV@28216|Betaproteobacteria 28216|Betaproteobacteria S Beta-ketoacyl synthase, N-terminal domain - - - - - - - - - - - - Ketoacyl-synt_2 DYD1_k127_3886716_13 756067.MicvaDRAFT_1425 4.388e-74 265.0 COG0106@1|root,COG0106@2|Bacteria,1G1S9@1117|Cyanobacteria,1H7RU@1150|Oscillatoriales 1117|Cyanobacteria E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD1_k127_3886716_14 748449.Halha_0992 6.323e-73 252.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WAQQ@53433|Halanaerobiales 186801|Clostridia E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase DYD1_k127_3886716_12 269799.Gmet_0386 3.059e-79 268.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria,43SWF@69541|Desulfuromonadales 28221|Deltaproteobacteria E imidazoleglycerol-phosphate dehydratase activity hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD DYD1_k127_3886716_5 1089553.Tph_c08830 4.8e-127 419.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,42EK0@68295|Thermoanaerobacterales 186801|Clostridia E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23,1.1.1.308 ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh DYD1_k127_3886716_3 56780.SYN_01793 3.631e-161 517.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,2MQ3Q@213462|Syntrophobacterales 28221|Deltaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase DYD1_k127_3886716_17 880072.Desac_0378 2.805e-66 237.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2MQKB@213462|Syntrophobacterales 28221|Deltaproteobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 DYD1_k127_3886716_4 1499967.BAYZ01000115_gene2927 2.514e-143 464.0 COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria 2|Bacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD1_k127_3886716_22 880073.Calab_1926 2.408e-28 115.0 COG0254@1|root,COG0254@2|Bacteria,2NPUV@2323|unclassified Bacteria 2|Bacteria J Binds the 23S rRNA rpmE GO:0008150,GO:0040007 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 DYD1_k127_3886716_7 1242864.D187_009124 6.534e-109 366.0 COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria 28221|Deltaproteobacteria O ATPase with chaperone activity - - - - - - - - - - - - AAA DYD1_k127_3886716_24 1265505.ATUG01000002_gene1033 1.278e-20 98.0 COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1R4E8@1224|Proteobacteria,42Q65@68525|delta/epsilon subdivisions,2WMAM@28221|Deltaproteobacteria,2MHQ5@213118|Desulfobacterales 28221|Deltaproteobacteria T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c,Response_reg DYD1_k127_3886716_8 365528.KB891257_gene4784 4.768e-100 347.0 COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria 201174|Actinobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_3886716_11 1380394.JADL01000009_gene3308 7.485e-89 302.0 28JPA@1|root,2Z9FC@2|Bacteria,1PN1F@1224|Proteobacteria,2TSKX@28211|Alphaproteobacteria,2JUBG@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD1_k127_3886716_26 748247.AZKH_4257 6.183e-07 58.0 COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,2VQ9W@28216|Betaproteobacteria,2KYMP@206389|Rhodocyclales 206389|Rhodocyclales C cysteine dioxygenase type I - - - - - - - - - - - - CDO_I DYD1_k127_3894845_4 472759.Nhal_0268 2.101e-20 93.0 COG2336@1|root,COG2336@2|Bacteria,1N9Z6@1224|Proteobacteria,1SDVP@1236|Gammaproteobacteria,1WZMC@135613|Chromatiales 135613|Chromatiales T SpoVT / AbrB like domain - - - ko:K07172 - - - - ko00000,ko02048 - - - MazE_antitoxin DYD1_k127_3894845_2 1122223.KB890700_gene2094 6.949e-46 168.0 COG2337@1|root,COG2337@2|Bacteria,1WMWG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD1_k127_3894845_5 1238450.VIBNISOn1_30094 2.213e-09 61.0 COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,1RQD6@1236|Gammaproteobacteria,1XTYB@135623|Vibrionales 135623|Vibrionales C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_3894845_1 535289.Dtpsy_2869 9.706e-87 297.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD1_k127_3894845_3 1502851.FG93_01002 1.852e-27 117.0 29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2U5KG@28211|Alphaproteobacteria,3JYK2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD1_k127_3894845_0 1510531.JQJJ01000015_gene3001 8.915e-196 623.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JX4Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD1_k127_389958_2 671143.DAMO_0714 4.013e-19 89.0 2CBZI@1|root,339ZR@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_389958_1 1396418.BATQ01000166_gene1863 2.412e-82 280.0 COG3361@1|root,COG3361@2|Bacteria,46X33@74201|Verrucomicrobia,2IUDI@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Uncharacterized conserved protein (COG2071) - - - - - - - - - - - - DUF2071 DYD1_k127_389958_3 1894.JOER01000017_gene4878 1.537e-14 78.0 2FEHJ@1|root,346H3@2|Bacteria,2IQM1@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_389958_5 1397693.KK211187_gene2462 1.248e-05 50.0 2DC3Y@1|root,2ZCTC@2|Bacteria,1U1X5@1239|Firmicutes,4IBDN@91061|Bacilli,3WFTZ@539002|Bacillales incertae sedis 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_389958_0 1380394.JADL01000001_gene2150 9.252e-94 317.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,2JPV4@204441|Rhodospirillales 204441|Rhodospirillales H Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N DYD1_k127_389958_4 404589.Anae109_0269 4.144e-13 71.0 COG1714@1|root,COG1714@2|Bacteria 2|Bacteria S RDD family - - - - - - - - - - - - RDD DYD1_k127_3907894_6 264732.Moth_0731 7.284e-40 154.0 COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,24AHX@186801|Clostridia,42FZR@68295|Thermoanaerobacterales 186801|Clostridia S Zn-dependent hydrolases of the - - - - - - - - - - - - Lactamase_B_3 DYD1_k127_3907894_2 357808.RoseRS_1484 3.753e-67 232.0 COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi,3763V@32061|Chloroflexia 32061|Chloroflexia C PFAM Alcohol dehydrogenase zinc-binding domain protein - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_3907894_4 671143.DAMO_2098 1.172e-62 218.0 COG0604@1|root,COG0604@2|Bacteria,2NQR7@2323|unclassified Bacteria 2|Bacteria C Zinc-binding dehydrogenase qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_3907894_7 671143.DAMO_2368 3.197e-18 93.0 COG3678@1|root,COG3678@2|Bacteria,2NRWA@2323|unclassified Bacteria 2|Bacteria NPTU Evidence 5 No homology to any previously reported sequences - - - - - - - - - - - - Metal_resist DYD1_k127_3907894_1 1210884.HG799465_gene12277 4.525e-86 294.0 COG1834@1|root,COG1834@2|Bacteria,2IXSX@203682|Planctomycetes 203682|Planctomycetes E Amidinotransferase - - - - - - - - - - - - Amidinotransf DYD1_k127_3907894_0 575540.Isop_1423 2.205e-137 449.0 COG1915@1|root,COG1915@2|Bacteria,2IWVZ@203682|Planctomycetes 203682|Planctomycetes S PFAM LOR SDH bifunctional - - - - - - - - - - - - Saccharop_dh_N DYD1_k127_3907894_8 861299.J421_2404 3.779e-18 91.0 2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - DYD1_k127_3907894_9 118166.JH976537_gene3498 1.179e-05 52.0 COG1359@1|root,COG1359@2|Bacteria,1G82P@1117|Cyanobacteria,1HCRV@1150|Oscillatoriales 1117|Cyanobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM DYD1_k127_3907894_5 935836.JAEL01000110_gene705 1.321e-45 181.0 COG0477@1|root,COG2814@2|Bacteria,1UIZZ@1239|Firmicutes,4ISYZ@91061|Bacilli,1ZSFR@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_3907894_3 1168034.FH5T_10880 1.568e-66 239.0 COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,2FMMH@200643|Bacteroidia 976|Bacteroidetes H acetolactate synthase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_3921050_3 690850.Desaf_2327 4.055e-44 171.0 COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria,42UB4@68525|delta/epsilon subdivisions,2WQJ3@28221|Deltaproteobacteria,2MBT8@213115|Desulfovibrionales 28221|Deltaproteobacteria S PFAM Rhomboid family protein - - - - - - - - - - - - Rhomboid DYD1_k127_3921050_4 1232410.KI421413_gene568 1.507e-05 49.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42P6W@68525|delta/epsilon subdivisions,2WIWM@28221|Deltaproteobacteria,43UAN@69541|Desulfuromonadales 28221|Deltaproteobacteria L HsdM N-terminal domain - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase DYD1_k127_3921050_1 189753.AXAS01000041_gene2534 6.032e-58 211.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_3921050_0 204669.Acid345_2166 2.57e-222 698.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - B12-binding,Dak2,DegV,Radical_SAM DYD1_k127_3921050_2 313612.L8106_28786 4.661e-46 174.0 COG2755@1|root,COG2755@2|Bacteria,1G8DF@1117|Cyanobacteria,1HFNB@1150|Oscillatoriales 1117|Cyanobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 DYD1_k127_3980174_2 349161.Dred_2112 1.999e-05 53.0 COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,262QH@186807|Peptococcaceae 186801|Clostridia U TadE-like protein - - - - - - - - - - - - TadE DYD1_k127_3980174_0 225849.swp_0420 2.298e-40 166.0 COG4961@1|root,COG4961@2|Bacteria,1QV5Z@1224|Proteobacteria 1224|Proteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad DYD1_k127_3997339_0 335543.Sfum_2336 6.524e-297 917.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,43DIW@68525|delta/epsilon subdivisions,2X8Q7@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Catalyzes the reversible hydration of fumarate to (S)- malate fumB - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C DYD1_k127_3997339_6 1196031.ALEG01000015_gene5168 1.68e-10 67.0 COG1225@1|root,COG1225@2|Bacteria,1UMIN@1239|Firmicutes,4ITW0@91061|Bacilli,1ZSDJ@1386|Bacillus 91061|Bacilli O AhpC/TSA antioxidant enzyme - - - - - - - - - - - - AhpC-TSA_2 DYD1_k127_3997339_3 330214.NIDE1495 2.813e-39 150.0 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif rbpA - - - - - - - - - - - RRM_1 DYD1_k127_3997339_1 331869.BAL199_27206 1.427e-107 353.0 COG0412@1|root,COG0412@2|Bacteria,1R9JT@1224|Proteobacteria,2U4J1@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH DYD1_k127_3997339_4 105425.BBPL01000003_gene6797 2.126e-18 88.0 2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria,2NJJ6@228398|Streptacidiphilus 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_3997339_2 1521187.JPIM01000019_gene372 2.27e-57 215.0 COG0477@1|root,COG2814@2|Bacteria,2GBHK@200795|Chloroflexi,376GU@32061|Chloroflexia 32061|Chloroflexia EGP major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_3 DYD1_k127_3997339_7 645991.Sgly_1020 1.453e-08 66.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_3997339_5 1118054.CAGW01000075_gene3261 2.507e-18 97.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_3999499_0 909663.KI867150_gene2871 1.897e-150 490.0 COG3039@1|root,COG3039@2|Bacteria,1QY2X@1224|Proteobacteria 1224|Proteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_6 DYD1_k127_3999499_1 435832.HMPREF0604_01421 1.35e-56 214.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KQPW@206351|Neisseriales 206351|Neisseriales S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 DYD1_k127_3999518_2 865861.AZSU01000002_gene3093 4.783e-43 162.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,36GMS@31979|Clostridiaceae 186801|Clostridia P ABC-type nitrate sulfonate bicarbonate transport system ATPase component - - - ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - ABC_tran DYD1_k127_3999518_3 477184.KYC_12268 1.703e-19 99.0 COG3473@1|root,COG3473@2|Bacteria,1N3F7@1224|Proteobacteria,2VX2N@28216|Betaproteobacteria,3T53U@506|Alcaligenaceae 28216|Betaproteobacteria Q Catalyzes the conversion of maleate to fumarate - - 4.1.1.76,5.2.1.1 ko:K01799,ko:K06033 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD1_k127_3999518_1 1205680.CAKO01000037_gene1313 4.929e-126 423.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 DYD1_k127_3999518_0 234267.Acid_3907 3.199e-292 922.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,3Y7CF@57723|Acidobacteria 57723|Acidobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N DYD1_k127_4006047_1 483219.LILAB_35055 6.938e-45 169.0 COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WM9S@28221|Deltaproteobacteria,2YZVS@29|Myxococcales 28221|Deltaproteobacteria S Haem-binding uptake, Tiki superfamily, ChaN - - - - - - - - - - - - Cofac_haem_bdg,PDZ_2 DYD1_k127_4006047_4 1173263.Syn7502_03004 0.0003535 52.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_4006047_2 1120953.AUBH01000002_gene1512 3.141e-35 139.0 COG3631@1|root,COG3631@2|Bacteria,1RD0K@1224|Proteobacteria,1S8NU@1236|Gammaproteobacteria,46ATH@72275|Alteromonadaceae 1236|Gammaproteobacteria S SnoaL-like domain - - - ko:K06893 - - - - ko00000 - - - SnoaL_2 DYD1_k127_4006047_3 1485544.JQKP01000001_gene1160 1.355e-06 54.0 COG2963@1|root,COG2963@2|Bacteria,1N3E0@1224|Proteobacteria,2VYHT@28216|Betaproteobacteria,44WKH@713636|Nitrosomonadales 28216|Betaproteobacteria L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 DYD1_k127_4006047_0 1547437.LL06_00635 2.438e-96 321.0 COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,43JX9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Belongs to the UPF0061 (SELO) family - - - ko:K08997 - - - - ko00000 - - - UPF0061 DYD1_k127_4022804_1 1123371.ATXH01000008_gene253 9.66e-83 279.0 COG0040@1|root,COG0040@2|Bacteria,2GHDQ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria E ATP phosphoribosyltransferase hisG - 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C DYD1_k127_4022804_0 273068.TTE1336 2.081e-179 573.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,42EY5@68295|Thermoanaerobacterales 186801|Clostridia C PFAM Conserved carboxylase region pycB - 4.1.1.3,6.4.1.1 ko:K01571,ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00217,R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000,ko02000 3.B.1.1.1 - - Biotin_lipoyl,HMGL-like,PYC_OADA DYD1_k127_4022804_2 1131269.AQVV01000011_gene2496 8.595e-06 55.0 COG1245@1|root,COG1245@2|Bacteria 2|Bacteria C 4Fe-4S binding domain rnfB - 1.8.99.2 ko:K00395,ko:K02572,ko:K03616 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FeS,Fer4,Fer4_4,Fer4_7 DYD1_k127_403180_1 1294142.CINTURNW_4023 3.206e-16 80.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,24HDS@186801|Clostridia,36FJX@31979|Clostridiaceae 186801|Clostridia C Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N DYD1_k127_403180_0 1499967.BAYZ01000016_gene6509 5.303e-59 224.0 COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria 2|Bacteria M Transglycosylase mrcA GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iAF987.Gmet_0354 PCB_OB,Transgly,Transpeptidase DYD1_k127_405804_3 330214.NIDE2073 2.54e-142 460.0 COG1389@1|root,COG1389@2|Bacteria 2|Bacteria L DNA topoisomerase II activity top6B - 5.99.1.3 ko:K03167 - - - - ko00000,ko01000,ko03032 - - - HATPase_c,HATPase_c_3,Topo-VIb_trans DYD1_k127_405804_0 330214.NIDE2074 1.028e-204 640.0 COG1697@1|root,COG1697@2|Bacteria 2|Bacteria L DNA topoisomerase VI subunit A top6A - 5.99.1.3 ko:K03166 - - - - ko00000,ko01000,ko03032 - - - DUF2220,DUF3322,TP6A_N DYD1_k127_405804_11 1120949.KB903314_gene303 2.413e-35 149.0 COG1840@1|root,COG1840@2|Bacteria 2|Bacteria P iron ion homeostasis - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_405804_14 1449063.JMLS01000027_gene61 1.493e-23 112.0 COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,26UYR@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_405804_9 225849.swp_0420 4.513e-48 190.0 COG4961@1|root,COG4961@2|Bacteria,1QV5Z@1224|Proteobacteria 1224|Proteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad DYD1_k127_405804_10 1268072.PSAB_03630 1.562e-39 161.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,26W4T@186822|Paenibacillaceae 91061|Bacilli C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_405804_13 204669.Acid345_3527 5.308e-24 105.0 COG0457@1|root,COG0457@2|Bacteria 204669.Acid345_3527|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_405804_15 459349.CLOAM0763 8.429e-15 86.0 COG0745@1|root,COG0745@2|Bacteria 459349.CLOAM0763|- T phosphorelay signal transduction system - - - - - - - - - - - - - DYD1_k127_405804_5 1382306.JNIM01000001_gene1548 2.919e-93 329.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - - - - - - - - - - - DYD1_k127_405804_6 1340493.JNIF01000003_gene4218 1.174e-85 291.0 COG1738@1|root,COG1738@2|Bacteria,3Y35H@57723|Acidobacteria 57723|Acidobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 DYD1_k127_405804_2 1232410.KI421418_gene2301 1.255e-149 492.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,43S6M@69541|Desulfuromonadales 28221|Deltaproteobacteria L DHH family recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD1_k127_405804_7 56780.SYN_01525 3.992e-80 276.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2MQS8@213462|Syntrophobacterales 28221|Deltaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG DYD1_k127_405804_1 56780.SYN_01524 7.668e-167 539.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MR54@213462|Syntrophobacterales 28221|Deltaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG DYD1_k127_405804_12 485915.Dret_0845 7.992e-29 119.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MCSM@213115|Desulfovibrionales 28221|Deltaproteobacteria U TIGRFAM preprotein translocase, YajC subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC DYD1_k127_405804_4 443143.GM18_2293 3.895e-136 447.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43TNC@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT DYD1_k127_405804_8 429009.Adeg_1584 6.569e-50 181.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,42ETD@68295|Thermoanaerobacterales 186801|Clostridia J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth DYD1_k127_4076490_0 709797.CSIRO_2188 2.946e-89 299.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family MA20_23145 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD1_k127_4076490_1 189753.AXAS01000041_gene2534 1.033e-84 291.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_4076490_2 309807.SRU_0586 5.329e-27 112.0 COG1708@1|root,COG1708@2|Bacteria 2|Bacteria S nucleotidyltransferase activity - - - ko:K07076 - - - - ko00000 - - - HEPN,NTP_transf_2 DYD1_k127_4076490_3 909613.UO65_5972 7.574e-05 48.0 COG0715@1|root,COG0715@2|Bacteria,2I9KK@201174|Actinobacteria,4E19Q@85010|Pseudonocardiales 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - - - - - - - - - - NMT1,NMT1_2 DYD1_k127_4080048_12 404380.Gbem_2640 5.661e-35 144.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,43U6A@69541|Desulfuromonadales 28221|Deltaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C DYD1_k127_4080048_0 335543.Sfum_0551 7.056e-282 877.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2MQTC@213462|Syntrophobacterales 28221|Deltaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD1_k127_4080048_7 1379698.RBG1_1C00001G1625 4.27e-86 297.0 COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria 2|Bacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind DYD1_k127_4080048_10 1232410.KI421415_gene3038 6.752e-74 260.0 COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,43SDZ@69541|Desulfuromonadales 28221|Deltaproteobacteria S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N DYD1_k127_4080048_14 1121430.JMLG01000011_gene356 1.287e-16 91.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,2612S@186807|Peptococcaceae 186801|Clostridia S PFAM YbbR-like protein - - - - - - - - - - - - YbbR DYD1_k127_4080048_2 338963.Pcar_1001 2.709e-173 556.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,43T4H@69541|Desulfuromonadales 28221|Deltaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iAF987.Gmet_1886 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD1_k127_4080048_9 290398.Csal_1634 1.892e-79 273.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1XHGB@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ DYD1_k127_4080048_4 667014.Thein_1837 2.483e-136 450.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GHEJ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD1_k127_4080048_13 767817.Desgi_2354 9.238e-34 135.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae 186801|Clostridia S PFAM Uncharacterised P-loop hydrolase UPF0079 ydiB - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE DYD1_k127_4080048_3 1232410.KI421415_gene3029 5.627e-159 511.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,43U9Z@69541|Desulfuromonadales 28221|Deltaproteobacteria E PFAM aspartate glutamate uridylate kinase lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 DYD1_k127_4080048_1 243231.GSU1798 2.187e-207 664.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,43TBU@69541|Desulfuromonadales 28221|Deltaproteobacteria E Belongs to the alpha-IPM synthase homocitrate synthase family cimA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer DYD1_k127_4080048_8 1232410.KI421413_gene846 1.946e-83 284.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,43S76@69541|Desulfuromonadales 28221|Deltaproteobacteria E Serine acetyltransferase, N-terminal cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N DYD1_k127_4080048_6 316067.Geob_1979 3.474e-102 344.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans DYD1_k127_4080048_5 56780.SYN_00797 2.05e-118 395.0 COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2MQCJ@213462|Syntrophobacterales 28221|Deltaproteobacteria J MiaB-like tRNA modifying enzyme mtaB - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 DYD1_k127_4080048_11 1125863.JAFN01000001_gene557 1.779e-54 201.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm DYD1_k127_4089436_1 1267533.KB906737_gene1538 9.556e-48 183.0 COG5563@1|root,COG5563@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF3466,VPEP DYD1_k127_4089436_0 880072.Desac_1175 1.948e-75 259.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales 28221|Deltaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD1_k127_4089436_2 404589.Anae109_0789 9.672e-46 174.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,42S5S@68525|delta/epsilon subdivisions,2WNSS@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Lysin motif - - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 DYD1_k127_4089436_3 309801.trd_0447 2.494e-26 115.0 COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,27XXF@189775|Thermomicrobia 189775|Thermomicrobia E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_4096011_0 330214.NIDE3866 2.4e-322 1009.0 COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,3J0ZI@40117|Nitrospirae 40117|Nitrospirae C ATP-grasp domain - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD1_k127_4097309_19 391613.RTM1035_04135 1.339e-20 92.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria,46S3E@74030|Roseovarius 28211|Alphaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 DYD1_k127_4097309_20 76114.p2A120 3.13e-07 55.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_4097309_0 1380387.JADM01000006_gene1090 7.323e-308 958.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1XHJX@135619|Oceanospirillales 135619|Oceanospirillales C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase DYD1_k127_4097309_23 1504319.GM45_0390 0.0004424 45.0 COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,3UWR5@52018|unclassified Actinobacteria (class) 201174|Actinobacteria O Redoxin ahpE GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - AhpC-TSA DYD1_k127_4097309_15 485913.Krac_6534 9.138e-32 127.0 COG1225@1|root,COG1278@1|root,COG1225@2|Bacteria,COG1278@2|Bacteria 2|Bacteria K Cold shock cspA - - ko:K03704 - - - - ko00000,ko03000 - - - AhpC-TSA,CSD DYD1_k127_4097309_17 197221.22294597 5.862e-23 100.0 COG0271@1|root,COG0271@2|Bacteria,1G7V3@1117|Cyanobacteria 1117|Cyanobacteria T Belongs to the BolA IbaG family colA - - - - - - - - - - - BolA DYD1_k127_4097309_11 82654.Pse7367_0668 6.625e-40 150.0 COG0278@1|root,COG0278@2|Bacteria,1G6JA@1117|Cyanobacteria,1HBMV@1150|Oscillatoriales 1117|Cyanobacteria C Belongs to the glutaredoxin family. Monothiol subfamily ycf64 - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin DYD1_k127_4097309_18 690850.Desaf_0463 3.485e-22 100.0 COG0457@1|root,COG0457@2|Bacteria 690850.Desaf_0463|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD1_k127_4097309_6 671143.DAMO_1169 2.372e-69 246.0 2C8XG@1|root,2Z7PK@2|Bacteria,2NR2W@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 DYD1_k127_4097309_10 70601.3257399 5.994e-47 177.0 COG3473@1|root,arCOG02004@2157|Archaea,2XUJ3@28890|Euryarchaeota,24328@183968|Thermococci 28890|Euryarchaeota Q Asp/Glu/Hydantoin racemase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD1_k127_4097309_22 768710.DesyoDRAFT_0324 0.0001286 52.0 COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,24MK8@186801|Clostridia,2624R@186807|Peptococcaceae 186801|Clostridia S PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - ko:K05967 - - - - ko00000 - - - NT5C DYD1_k127_4097309_9 246196.MSMEI_2053 3.414e-54 206.0 COG0624@1|root,COG0624@2|Bacteria,2I9Y6@201174|Actinobacteria,23ER8@1762|Mycobacteriaceae 201174|Actinobacteria E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD1_k127_4097309_21 1122915.AUGY01000020_gene6489 3.754e-07 61.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_4097309_14 671143.DAMO_3026 2.257e-33 132.0 COG2329@1|root,COG2329@2|Bacteria,2NS2V@2323|unclassified Bacteria 2|Bacteria S Evidence 4 Homologs of previously reported genes of isdG - 1.14.99.48,1.14.99.57 ko:K07145,ko:K21481 ko00860,ko01110,map00860,map01110 - R10468,R10510 RC03185 ko00000,ko00001,ko01000 - - - ABM DYD1_k127_4097309_5 1380355.JNIJ01000031_gene3513 7.412e-98 330.0 COG2141@1|root,COG2141@2|Bacteria,1QGWA@1224|Proteobacteria,2UNBA@28211|Alphaproteobacteria,3K5C8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Luciferase-like monooxygenase - - 1.5.98.2 ko:K00320 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R04464 RC01607 ko00000,ko00001,ko00002,ko01000 - - - Bac_luciferase DYD1_k127_4097309_1 1125971.ASJB01000043_gene3378 2.922e-251 792.0 COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4E9VD@85010|Pseudonocardiales 201174|Actinobacteria EQ Hydantoinase/oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A DYD1_k127_4097309_2 1089545.KB913037_gene2990 3.101e-213 677.0 COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4E8PZ@85010|Pseudonocardiales 201174|Actinobacteria EQ Hydantoinase B/oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B DYD1_k127_4097309_8 871968.DESME_09210 2.307e-57 213.0 COG1028@1|root,COG1028@2|Bacteria,1V05R@1239|Firmicutes,249EC@186801|Clostridia,2602W@186807|Peptococcaceae 186801|Clostridia IQ PFAM short chain dehydrogenase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_4097309_13 448385.sce1239 6.203e-38 150.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,42RDD@68525|delta/epsilon subdivisions,2X6JS@28221|Deltaproteobacteria,2Z3BH@29|Myxococcales 28221|Deltaproteobacteria G KDPG and KHG aldolase - - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase DYD1_k127_4097309_4 1134413.ANNK01000086_gene318 2.656e-117 386.0 COG0715@1|root,COG0715@2|Bacteria,1TXP3@1239|Firmicutes,4I6PJ@91061|Bacilli,1ZM9Z@1386|Bacillus 91061|Bacilli P NMT1/THI5 like - - - - - - - - - - - - NMT1 DYD1_k127_4097309_12 264732.Moth_0731 1.311e-39 159.0 COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,24AHX@186801|Clostridia,42FZR@68295|Thermoanaerobacterales 186801|Clostridia S Zn-dependent hydrolases of the - - - - - - - - - - - - Lactamase_B_3 DYD1_k127_4097309_7 593117.TGAM_0604 6.051e-67 236.0 COG3839@1|root,arCOG00175@2157|Archaea,2Y7MN@28890|Euryarchaeota,2431V@183968|Thermococci 183968|Thermococci G Function Code 14.4 Transport and Binding Proteins Carbohydrates, organic alcohols, and acids - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 DYD1_k127_4097309_16 405948.SACE_4446 1.271e-25 115.0 COG5424@1|root,COG5424@2|Bacteria,2I9SS@201174|Actinobacteria,4E05W@85010|Pseudonocardiales 201174|Actinobacteria H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ pqqC - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4 DYD1_k127_4097309_3 240015.ACP_0847 7.888e-123 403.0 COG2008@1|root,COG2008@2|Bacteria,3Y472@57723|Acidobacteria,2JIUS@204432|Acidobacteriia 204432|Acidobacteriia E PFAM aromatic amino acid beta-eliminating lyase threonine aldolase - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase DYD1_k127_410333_0 335543.Sfum_0758 2.585e-96 338.0 COG4775@1|root,COG4775@2|Bacteria,1QX52@1224|Proteobacteria,43CEZ@68525|delta/epsilon subdivisions,2X7PY@28221|Deltaproteobacteria,2MRBQ@213462|Syntrophobacterales 28221|Deltaproteobacteria M Surface antigen - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA DYD1_k127_410333_1 1089552.KI911559_gene3261 7.19e-33 149.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2JQWJ@204441|Rhodospirillales 204441|Rhodospirillales S TamB, inner membrane protein subunit of TAM complex - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB DYD1_k127_4105044_1 292415.Tbd_2466 4.157e-55 205.0 2DMNF@1|root,32SNT@2|Bacteria,1RA9F@1224|Proteobacteria,2WG9V@28216|Betaproteobacteria 28216|Betaproteobacteria S FRG - - - - - - - - - - - - FRG DYD1_k127_4105044_6 75379.Tint_1400 4.596e-11 69.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHC7@28216|Betaproteobacteria,1KKW2@119065|unclassified Burkholderiales 28216|Betaproteobacteria L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve DYD1_k127_4105044_0 1439940.BAY1663_03015 1.995e-55 204.0 COG2197@1|root,COG2197@2|Bacteria,1RGN8@1224|Proteobacteria 1224|Proteobacteria K Response regulator, receiver - - - - - - - - - - - - GerE,Response_reg DYD1_k127_4110608_3 351160.RCIX226 1.009e-17 89.0 COG1712@1|root,arCOG00254@2157|Archaea,2XUNA@28890|Euryarchaeota,2NBJI@224756|Methanomicrobia 224756|Methanomicrobia F Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate nadX - 1.4.1.21 ko:K06989 ko00760,ko01100,map00760,map01100 - R07407,R07410 RC02566 ko00000,ko00001,ko01000 - - - DUF108,NAD_binding_3 DYD1_k127_4110608_0 278957.ABEA03000218_gene237 2.46e-51 194.0 COG5616@1|root,COG5616@2|Bacteria,46XZ9@74201|Verrucomicrobia,3K8NU@414999|Opitutae 414999|Opitutae S Curli production assembly/transport component CsgG - - - - - - - - - - - - CsgG DYD1_k127_4110608_5 1167006.UWK_02683 1.257e-08 65.0 COG3417@1|root,COG3417@2|Bacteria 2|Bacteria M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) lpoB GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K07337,ko:K21008 ko02025,map02025 - - - ko00000,ko00001 - - - LpoB DYD1_k127_4110608_6 1278073.MYSTI_04051 7.522e-06 60.0 COG5616@1|root,COG5616@2|Bacteria,1QW0Q@1224|Proteobacteria,43303@68525|delta/epsilon subdivisions,2WXN6@28221|Deltaproteobacteria,2Z1XR@29|Myxococcales 28221|Deltaproteobacteria S Curli production assembly/transport component CsgG - - - - - - - - - - - - CsgG DYD1_k127_4110608_4 604331.AUHY01000038_gene136 2.869e-12 72.0 2DGZ3@1|root,2ZXUD@2|Bacteria,1WKRC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Antitoxin Phd_YefM, type II toxin-antitoxin system - - - - - - - - - - - - PhdYeFM_antitox DYD1_k127_4110608_1 1123386.AUIW01000009_gene1812 3.68e-33 134.0 COG1848@1|root,COG1848@2|Bacteria,1WKJ4@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - - DYD1_k127_4110608_2 1122915.AUGY01000118_gene6525 9.158e-19 96.0 COG0715@1|root,COG0715@2|Bacteria,1UZYY@1239|Firmicutes,4HE24@91061|Bacilli,26RHH@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_4113775_4 104623.Ser39006_02209 0.0003912 43.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family intA - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase DYD1_k127_4113775_3 1232410.KI421413_gene670 2.258e-29 120.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria,43SR6@69541|Desulfuromonadales 28221|Deltaproteobacteria K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 DYD1_k127_4113775_2 443143.GM18_2213 6.079e-33 130.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42TK0@68525|delta/epsilon subdivisions,2WQ5D@28221|Deltaproteobacteria,43VBY@69541|Desulfuromonadales 28221|Deltaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA - - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD1_k127_4113775_0 335543.Sfum_0429 4.446e-158 523.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MQAI@213462|Syntrophobacterales 28221|Deltaproteobacteria J TIGRFAM phenylalanyl-tRNA synthetase, beta subunit pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind DYD1_k127_4113775_1 243231.GSU1519 5.707e-134 434.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,43TP6@69541|Desulfuromonadales 28221|Deltaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAF987.Gmet_1415 Phe_tRNA-synt_N,tRNA-synt_2d DYD1_k127_4121767_1 595537.Varpa_0469 7.127e-50 185.0 COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,2VJU6@28216|Betaproteobacteria,4ACFC@80864|Comamonadaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1016) - - - - - - - - - - - - DUF1016 DYD1_k127_4121767_0 768671.ThimaDRAFT_2928 1.682e-112 369.0 COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,1RY9R@1236|Gammaproteobacteria,1WZ9T@135613|Chromatiales 1236|Gammaproteobacteria S Protein of unknown function (DUF1016) - - - - - - - - - - - - DUF1016 DYD1_k127_4121905_6 318586.Pden_1128 2.746e-07 62.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2TUPX@28211|Alphaproteobacteria,2PVED@265|Paracoccus 28211|Alphaproteobacteria S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA DYD1_k127_4121905_4 862908.BMS_1027 1.153e-20 99.0 COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2MTD6@213481|Bdellovibrionales,2WRCE@28221|Deltaproteobacteria 213481|Bdellovibrionales U Biopolymer transport protein ExbD TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD DYD1_k127_4121905_3 862908.BMS_1026 1.836e-27 120.0 COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,42TPM@68525|delta/epsilon subdivisions,2WW8Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB DYD1_k127_4121905_7 251221.35213978 1.677e-05 57.0 COG0810@1|root,COG1714@1|root,COG0810@2|Bacteria,COG1714@2|Bacteria,1GQMS@1117|Cyanobacteria 1117|Cyanobacteria M TIGRFAM TonB family C-terminal domain - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - RDD,TonB_2 DYD1_k127_4121905_5 1297742.A176_01322 1.924e-19 101.0 COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2Z1RM@29|Myxococcales 28221|Deltaproteobacteria S repeat protein - - - - - - - - - - - - - DYD1_k127_4121905_2 933262.AXAM01000026_gene3094 5.455e-42 169.0 COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2MN1B@213118|Desulfobacterales 28221|Deltaproteobacteria S repeat protein - - - - - - - - - - - - - DYD1_k127_4121905_1 1304874.JAFY01000002_gene1053 7.617e-65 243.0 COG1807@1|root,COG1807@2|Bacteria,3TAR6@508458|Synergistetes 508458|Synergistetes M PFAM glycosyl transferase family 39 - - 2.4.2.43 ko:K07264 ko01503,map01503 M00721 R09773,R09774,R09781 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - - - PMT_2 DYD1_k127_4121905_0 485915.Dret_1291 4.729e-68 238.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WKPK@28221|Deltaproteobacteria,2M86C@213115|Desulfovibrionales 28221|Deltaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA DYD1_k127_4126263_17 911239.CF149_01849 7.943e-06 48.0 COG1024@1|root,COG1024@2|Bacteria,1MVB1@1224|Proteobacteria,1RQQX@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family hcaA - 4.1.2.41,4.2.1.101 ko:K18383 ko00360,ko01100,ko01110,map00360,map01100,map01110 - R05772,R05773 RC00307,RC01468,RC01828 ko00000,ko00001,ko01000 - - iJN746.PP_3358 ECH_1 DYD1_k127_4126263_6 29540.C481_20726 3.052e-77 271.0 arCOG10131@1|root,arCOG10131@2157|Archaea,2XWNY@28890|Euryarchaeota,23V3W@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - DYD1_k127_4126263_9 1116472.MGMO_15c00080 1.194e-35 139.0 COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SA4A@1236|Gammaproteobacteria,1XFUA@135618|Methylococcales 135618|Methylococcales L Protein of unknown function (DUF559) - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - DUF559 DYD1_k127_4126263_15 29540.C481_20731 4.33e-10 63.0 arCOG10135@1|root,arCOG10135@2157|Archaea,2XY9Z@28890|Euryarchaeota,23W2D@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - DYD1_k127_4126263_16 477641.MODMU_2937 1.204e-09 62.0 2BZD4@1|root,332J5@2|Bacteria,2IPP3@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_4126263_5 29540.C481_20726 8.832e-79 275.0 arCOG10131@1|root,arCOG10131@2157|Archaea,2XWNY@28890|Euryarchaeota,23V3W@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - DYD1_k127_4126263_13 29540.C481_20731 2.792e-13 72.0 arCOG10135@1|root,arCOG10135@2157|Archaea,2XY9Z@28890|Euryarchaeota,23W2D@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - DYD1_k127_4126263_18 29540.C481_20731 0.0002451 48.0 arCOG10135@1|root,arCOG10135@2157|Archaea,2XY9Z@28890|Euryarchaeota,23W2D@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - DYD1_k127_4126263_0 448385.sce8781 2.492e-199 636.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2YXCT@29|Myxococcales 28221|Deltaproteobacteria L DNA polymerase beta thumb - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP DYD1_k127_4126263_8 404589.Anae109_1512 1.307e-44 169.0 2CFSQ@1|root,32S2E@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4126263_12 1184267.A11Q_422 1.618e-19 90.0 2BW7N@1|root,32Z97@2|Bacteria,1P2ZF@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_4126263_1 880073.Calab_3781 5.211e-133 431.0 COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria 2|Bacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD1_k127_4126263_2 1121937.AUHJ01000004_gene1056 4.05e-99 333.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,464QV@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 Gp_dh_C,Gp_dh_N DYD1_k127_4126263_4 448385.sce4660 1.951e-80 283.0 COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2Z3JZ@29|Myxococcales 28221|Deltaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 DYD1_k127_4126263_7 1380394.JADL01000002_gene1437 2.229e-62 218.0 2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,2U9PI@28211|Alphaproteobacteria,2JT3N@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD1_k127_4126263_10 485913.Krac_9819 1.204e-31 131.0 2DQBG@1|root,335T7@2|Bacteria,2G96K@200795|Chloroflexi 200795|Chloroflexi C Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - - - - - - - - - - GRDB DYD1_k127_4126263_3 1463903.JOIZ01000001_gene487 6.463e-85 292.0 COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria 201174|Actinobacteria Q Pfam Cupin - - 1.13.11.38,1.13.11.4 ko:K00450,ko:K11948 ko00350,ko00624,ko01100,ko01120,map00350,map00624,map01100,map01120 - R02656,R07657 RC00764,RC00937 ko00000,ko00001,ko01000 - - - Cupin_2 DYD1_k127_4129183_9 522306.CAP2UW1_0011 3.941e-33 133.0 2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of Unknown function (DUF2784) - - - - - - - - - - - - DUF2784 DYD1_k127_4129183_8 1121877.JQKF01000018_gene2547 1.608e-34 141.0 COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4CN1R@84992|Acidimicrobiia 84992|Acidimicrobiia L NUDIX hydrolase - - - - - - - - - - - - - DYD1_k127_4129183_0 861299.J421_3809 1.367e-208 662.0 COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Carbohydrate phosphorylase - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DUF3417,Phosphorylase DYD1_k127_4129183_10 1304888.ATWF01000001_gene882 1.399e-25 113.0 COG0119@1|root,COG0119@2|Bacteria,2GF1G@200930|Deferribacteres 200930|Deferribacteres E LeuA allosteric (dimerisation) domain - - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer DYD1_k127_4129183_12 1382359.JIAL01000001_gene1397 1.089e-17 91.0 2CK1C@1|root,32SJA@2|Bacteria,3Y543@57723|Acidobacteria,2JJTF@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - DYD1_k127_4129183_4 439235.Dalk_3985 2.359e-81 283.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2MI3R@213118|Desulfobacterales 28221|Deltaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG DYD1_k127_4129183_3 1123508.JH636441_gene3445 7.191e-112 371.0 COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes 203682|Planctomycetes S ATPase associated with - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD1_k127_4129183_7 1040989.AWZU01000006_gene560 1.145e-53 200.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,3JTSB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD1_k127_4129183_6 671143.DAMO_3119 1.302e-62 226.0 COG1893@1|root,COG1893@2|Bacteria,2NPMG@2323|unclassified Bacteria 2|Bacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C DYD1_k127_4129183_2 891968.Anamo_1078 3.546e-119 391.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - 4.1.1.55 ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000 - - - NMT1 DYD1_k127_4129183_13 671143.DAMO_0689 4.904e-11 66.0 COG2331@1|root,COG2331@2|Bacteria 2|Bacteria P Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 DYD1_k127_4129183_1 56780.SYN_02371 2.618e-137 447.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MQ94@213462|Syntrophobacterales 28221|Deltaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 DYD1_k127_4129183_5 502025.Hoch_4956 5.997e-71 250.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2YU7R@29|Myxococcales 28221|Deltaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C DYD1_k127_4129640_1 1231391.AMZF01000008_gene1542 0.0007044 46.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_4129640_0 266117.Rxyl_1749 3.393e-154 500.0 COG1012@1|root,COG1012@2|Bacteria,2H1UT@201174|Actinobacteria,4CSB5@84995|Rubrobacteria 84995|Rubrobacteria C Aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_4132752_1 316067.Geob_3768 5.343e-50 190.0 COG4313@1|root,COG4313@2|Bacteria,1NW7I@1224|Proteobacteria,42ZUG@68525|delta/epsilon subdivisions,2WVAI@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg DYD1_k127_4132752_4 1298593.TOL_0864 0.0003462 48.0 COG3440@1|root,COG3440@2|Bacteria,1QMZT@1224|Proteobacteria,1SHT0@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Restriction endonuclease - - - - - - - - - - - - - DYD1_k127_4132752_2 1267535.KB906767_gene3005 2.817e-31 139.0 COG2271@1|root,COG2271@2|Bacteria,3Y5MH@57723|Acidobacteria 57723|Acidobacteria G PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_4132752_0 1120972.AUMH01000002_gene2761 2.674e-117 387.0 2C1EV@1|root,33RW1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Cupin_2 DYD1_k127_4132752_3 1408303.JNJJ01000004_gene837 9.915e-21 103.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,1ZC0Z@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_4140511_2 880072.Desac_2223 7.169e-16 78.0 COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,42SGU@68525|delta/epsilon subdivisions,2WPBP@28221|Deltaproteobacteria 28221|Deltaproteobacteria MU CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP DYD1_k127_4140511_1 269799.Gmet_1651 8.143e-111 371.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,43US6@69541|Desulfuromonadales 28221|Deltaproteobacteria M Biotin-lipoyl like - - - ko:K07799 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD1_k127_4140511_0 251221.35214602 0.0 1279.0 COG0841@1|root,COG0841@2|Bacteria,1G0C2@1117|Cyanobacteria 1117|Cyanobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran DYD1_k127_4140511_3 357808.RoseRS_2104 1.332e-11 75.0 COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia 32061|Chloroflexia MV PFAM secretion protein HlyD family protein - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 DYD1_k127_4150222_8 404380.Gbem_0454 7.136e-15 74.0 2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,43VXN@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4150222_10 568706.BN118_2122 1.255e-09 63.0 COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2WG5J@28216|Betaproteobacteria,3T7XW@506|Alcaligenaceae 28216|Betaproteobacteria S periplasmic or secreted lipoprotein - - - - - - - - - - - - BON DYD1_k127_4150222_3 909613.UO65_0943 6.199e-59 214.0 COG0664@1|root,COG0664@2|Bacteria,2INMI@201174|Actinobacteria,4EBXN@85010|Pseudonocardiales 201174|Actinobacteria K Cyclic nucleotide-monophosphate binding domain - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding DYD1_k127_4150222_11 926559.JoomaDRAFT_2328 5.347e-09 66.0 COG2020@1|root,COG2020@2|Bacteria,4NJCI@976|Bacteroidetes,1I1CA@117743|Flavobacteriia 976|Bacteroidetes O Protein of unknown function (DUF1295) - - - - - - - - - - - - PEMT DYD1_k127_4150222_5 665571.STHERM_c05430 1.081e-36 147.0 COG5000@1|root,COG5000@2|Bacteria,2J5RG@203691|Spirochaetes 203691|Spirochaetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8 DYD1_k127_4150222_2 56780.SYN_01953 1.448e-70 244.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales 28221|Deltaproteobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_4150222_4 292.DM42_4469 7.074e-40 172.0 COG0840@1|root,COG4585@1|root,COG0840@2|Bacteria,COG4585@2|Bacteria,1QTXI@1224|Proteobacteria,2VJYF@28216|Betaproteobacteria,1K461@119060|Burkholderiaceae 28216|Betaproteobacteria T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - HATPase_c,HisKA_3,MASE4,MCPsignal DYD1_k127_4150222_0 247490.KSU1_C1572 4.326e-265 858.0 COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,2IWSR@203682|Planctomycetes 203682|Planctomycetes NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,Response_reg DYD1_k127_4150222_1 1242864.D187_003348 3.973e-79 273.0 COG1524@1|root,COG1524@2|Bacteria 2|Bacteria S mannose-ethanolamine phosphotransferase activity - - - - - - - - - - - - 5_nucleotid_C,HYR,Laminin_G_3,Phosphodiest DYD1_k127_4150222_7 1254432.SCE1572_04020 6.502e-22 102.0 COG3054@1|root,COG3054@2|Bacteria,1Q8NR@1224|Proteobacteria,43883@68525|delta/epsilon subdivisions,2X3HU@28221|Deltaproteobacteria,2YW60@29|Myxococcales 28221|Deltaproteobacteria S Bacterial protein of unknown function (YtfJ_HI0045) - - - ko:K07109 - - - - ko00000 - - - YtfJ_HI0045 DYD1_k127_4150222_9 485913.Krac_11550 1.141e-09 64.0 COG1814@1|root,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi 200795|Chloroflexi S VIT family - - - - - - - - - - - - VIT1 DYD1_k127_4150222_6 111781.Lepto7376_0230 8.317e-23 106.0 COG4783@1|root,COG4783@2|Bacteria,1G1TE@1117|Cyanobacteria,1H9TK@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD1_k127_4151145_0 706587.Desti_3172 2.757e-112 370.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42Q8T@68525|delta/epsilon subdivisions,2WKQE@28221|Deltaproteobacteria 28221|Deltaproteobacteria S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA_5 DYD1_k127_4151145_4 1382356.JQMP01000004_gene231 5.044e-84 295.0 COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,27XNE@189775|Thermomicrobia 189775|Thermomicrobia S VWA domain containing CoxE-like protein - - - ko:K07161 - - - - ko00000 - - - VWA_CoxE DYD1_k127_4151145_8 926550.CLDAP_39560 2.395e-28 118.0 COG1975@1|root,COG1975@2|Bacteria 2|Bacteria O molybdopterin cofactor binding - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI DYD1_k127_4151145_6 574087.Acear_0467 1.895e-47 179.0 COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,3WBPN@53433|Halanaerobiales 186801|Clostridia O XdhC Rossmann domain pucA - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI DYD1_k127_4151145_9 387631.Asulf_02078 2.649e-14 81.0 COG1339@1|root,arCOG01904@2157|Archaea,2XTFW@28890|Euryarchaeota,245S3@183980|Archaeoglobi 183980|Archaeoglobi H Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) ribK - 2.7.1.161 ko:K07732 ko00740,ko01100,map00740,map01100 - R08574 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CTP-dep_RFKase,HTH_24 DYD1_k127_4151145_5 571.MC52_28310 1.294e-71 248.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2311,iAPECO1_1312.APECO1_4253,iB21_1397.B21_02196,iBWG_1329.BWG_2085,iE2348C_1286.E2348C_2451,iEC55989_1330.EC55989_2555,iECBD_1354.ECBD_1348,iECB_1328.ECB_02236,iECDH10B_1368.ECDH10B_2473,iECDH1ME8569_1439.ECDH1ME8569_2249,iECD_1391.ECD_02236,iECED1_1282.ECED1_2775,iECH74115_1262.ECH74115_3451,iECIAI39_1322.ECIAI39_2460,iECNA114_1301.ECNA114_2401,iECO103_1326.ECO103_2775,iECOK1_1307.ECOK1_2544,iECP_1309.ECP_2350,iECS88_1305.ECS88_2458,iECSE_1348.ECSE_2620,iECSF_1327.ECSF_2187,iECSP_1301.ECSP_3186,iECs_1301.ECs3195,iETEC_1333.ETEC_2447,iEcDH1_1363.EcDH1_1345,iEcE24377_1341.EcE24377A_2605,iEcHS_1320.EcHS_A2462,iEcSMS35_1347.EcSMS35_2467,iG2583_1286.G2583_2848,iJO1366.b2311,iJR904.b2311,iLF82_1304.LF82_2354,iNRG857_1313.NRG857_11705,iSDY_1059.SDY_2510,iUMN146_1321.UM146_05255,iUMNK88_1353.UMNK88_2862,iUTI89_1310.UTI89_C2595,iY75_1357.Y75_RS12120,iZ_1308.Z3573 Flavoprotein DYD1_k127_4151145_1 316274.Haur_4687 4.455e-109 363.0 COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi,374UE@32061|Chloroflexia 32061|Chloroflexia H Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh DYD1_k127_4151145_7 706587.Desti_2225 1.099e-36 145.0 COG3787@1|root,COG3787@2|Bacteria,1N6XR@1224|Proteobacteria,42VZH@68525|delta/epsilon subdivisions,2WRXK@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K09979 - - - - ko00000 - - - Putative_PNPOx DYD1_k127_4151145_10 1038869.AXAN01000003_gene2653 2.133e-13 76.0 2DAI9@1|root,32TVI@2|Bacteria,1R3N0@1224|Proteobacteria,2WIIK@28216|Betaproteobacteria,1K90U@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - Putative_PNPOx DYD1_k127_4151145_2 443143.GM18_2043 1.211e-100 346.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 DYD1_k127_4151145_3 671143.DAMO_3154 6.553e-90 302.0 COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria 2|Bacteria V ABC transporter macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_4153860_2 1173028.ANKO01000044_gene779 5.721e-77 271.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1HAHP@1150|Oscillatoriales 1117|Cyanobacteria S metal-dependent hydrolase of the TIM-barrel fold - - - - - - - - - - - - Amidohydro_2 DYD1_k127_4153860_6 331869.BAL199_27341 5.986e-08 62.0 2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,2U9PI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4153860_5 1382359.JIAL01000001_gene65 4.545e-13 73.0 COG1451@1|root,COG1451@2|Bacteria 2|Bacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 DYD1_k127_4153860_4 1382359.JIAL01000001_gene65 2.035e-16 79.0 COG1451@1|root,COG1451@2|Bacteria 2|Bacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 DYD1_k127_4153860_0 316056.RPC_1039 5.566e-245 765.0 COG3177@1|root,COG3177@2|Bacteria,1MVW0@1224|Proteobacteria,2TU9A@28211|Alphaproteobacteria,3JV8G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Fic/DOC family - - - - - - - - - - - - Fic DYD1_k127_4153860_3 189753.AXAS01000041_gene2534 3.347e-70 245.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_4153860_1 189753.AXAS01000041_gene2534 4.123e-87 299.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_4155127_7 886293.Sinac_7530 8.047e-26 109.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_4155127_9 1202768.JROF01000006_gene2450 1.217e-15 87.0 COG0697@1|root,arCOG00272@2157|Archaea,2XVSM@28890|Euryarchaeota,23S7J@183963|Halobacteria 183963|Halobacteria G COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD1_k127_4155127_8 68570.DC74_988 5.32e-22 101.0 2BCA3@1|root,325V8@2|Bacteria,2HB4V@201174|Actinobacteria 201174|Actinobacteria S YCII-related domain - - - - - - - - - - - - YCII DYD1_k127_4155127_5 1169161.KB897726_gene1441 4.903e-27 119.0 COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria 201174|Actinobacteria Q Catalyzes the conversion of maleate to fumarate - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD1_k127_4155127_10 1280950.HJO_16045 0.0006704 50.0 COG3473@1|root,COG3473@2|Bacteria,1RKZQ@1224|Proteobacteria,2U13U@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Maleate cis-trans isomerase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - - DYD1_k127_4155127_3 1254432.SCE1572_47310 4.229e-95 321.0 COG1475@1|root,COG1475@2|Bacteria,1Q2AH@1224|Proteobacteria,437X8@68525|delta/epsilon subdivisions,2X9QN@28221|Deltaproteobacteria,2YUMN@29|Myxococcales 28221|Deltaproteobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc DYD1_k127_4155127_4 1121440.AUMA01000007_gene1048 2.843e-70 253.0 COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2M927@213115|Desulfovibrionales 28221|Deltaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 DYD1_k127_4155127_0 1179778.PMM47T1_08116 1.088e-177 568.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - iZ_1308.Z4900 Pyr_redox_2,Pyr_redox_dim DYD1_k127_4155127_2 502025.Hoch_4484 2.257e-102 338.0 COG5424@1|root,COG5424@2|Bacteria,1Q9R2@1224|Proteobacteria,434J3@68525|delta/epsilon subdivisions,2X8WX@28221|Deltaproteobacteria,2Z0SN@29|Myxococcales 28221|Deltaproteobacteria H Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 DYD1_k127_4155127_6 479434.Sthe_2196 2.798e-26 113.0 COG1051@1|root,COG1051@2|Bacteria,2G74M@200795|Chloroflexi,27YGS@189775|Thermomicrobia 189775|Thermomicrobia F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX DYD1_k127_4155127_1 269799.Gmet_0138 5.021e-139 452.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales 28221|Deltaproteobacteria S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139,DUF4140 DYD1_k127_4159521_3 671143.DAMO_2525 4.445e-11 66.0 2EA3B@1|root,3348D@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4159521_0 472759.Nhal_0131 0.0 1800.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RQ0G@1236|Gammaproteobacteria,1WXEX@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD1_k127_4159521_2 485913.Krac_12067 2.524e-21 104.0 COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF983) - - - - - - - - - - - - DUF983 DYD1_k127_4159521_1 304371.MCP_0033 1.339e-59 209.0 COG2094@1|root,arCOG04295@2157|Archaea,2Y0AE@28890|Euryarchaeota,2NB07@224756|Methanomicrobia 224756|Methanomicrobia L alkylbase DNA N-glycosylase activity mpg - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco DYD1_k127_4177318_4 1033802.SSPSH_000183 1.06e-19 96.0 COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,1S5D9@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB DYD1_k127_4177318_0 1249634.D781_3823 1.341e-81 282.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RR3T@1236|Gammaproteobacteria,401SK@613|Serratia 1236|Gammaproteobacteria S Oxidoreductase - - - - - - - - - - - - Oxidored_molyb DYD1_k127_4177318_1 671143.DAMO_1590 1.98e-76 263.0 COG0755@1|root,COG0755@2|Bacteria,2NPG8@2323|unclassified Bacteria 2|Bacteria O Cytochrome C assembly protein ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736 Cytochrom_C_asm DYD1_k127_4177318_3 671143.DAMO_1589 4.603e-30 124.0 COG2332@1|root,COG2332@2|Bacteria 2|Bacteria O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE - - ko:K02197 - - - - ko00000 - - - CcmE DYD1_k127_4177318_2 246200.SPOA0198 8.296e-60 214.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,4NANA@97050|Ruegeria 28211|Alphaproteobacteria O Cytochrome c-type biogenesis protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD1_k127_4188106_0 635013.TherJR_1798 1.145e-171 565.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25ZXM@186807|Peptococcaceae 186801|Clostridia L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII DYD1_k127_4188106_1 880072.Desac_1165 5.737e-48 177.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,2MS0D@213462|Syntrophobacterales 28221|Deltaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD1_k127_423337_4 864069.MicloDRAFT_00011820 4.38e-30 123.0 2EB38@1|root,33540@2|Bacteria,1NBMZ@1224|Proteobacteria,2UXHG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_423337_0 478741.JAFS01000002_gene991 2.493e-149 481.0 COG3465@1|root,COG3465@2|Bacteria 2|Bacteria - - - - 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427,ko:K09388 - - - - ko00000,ko01000,ko02048 - - - Macro,Methylase_S DYD1_k127_423337_1 643648.Slip_1960 4.861e-52 190.0 2DNAB@1|root,32WEV@2|Bacteria,1VED3@1239|Firmicutes,24QBP@186801|Clostridia 186801|Clostridia S Domain of unknown function (DUF4433) - - - - - - - - - - - - DUF4433 DYD1_k127_423337_3 909663.KI867150_gene1178 6.458e-41 157.0 COG0758@1|root,COG0758@2|Bacteria,1P6DS@1224|Proteobacteria,4333P@68525|delta/epsilon subdivisions,2WY16@28221|Deltaproteobacteria 28221|Deltaproteobacteria LU DNA mediated transformation - - - - - - - - - - - - - DYD1_k127_423337_5 1183438.GKIL_0005 1.104e-18 94.0 2BWGV@1|root,33X6R@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_423337_2 469383.Cwoe_3600 2.726e-46 173.0 COG4637@1|root,COG4637@2|Bacteria,2HRMF@201174|Actinobacteria,4CTPD@84995|Rubrobacteria 84995|Rubrobacteria S AAA ATPase domain - - - - - - - - - - - - AAA_21 DYD1_k127_4242242_0 1279019.ARQK01000048_gene140 6.611e-97 340.0 COG0433@1|root,COG0561@1|root,COG0433@2|Bacteria,COG0561@2|Bacteria,1P5B8@1224|Proteobacteria 1224|Proteobacteria S Haloacid dehalogenase domain protein hydrolase, type 3 - - - - - - - - - - - - Hydrolase_3 DYD1_k127_4242242_2 909663.KI867149_gene3210 3.514e-43 166.0 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,43ACP@68525|delta/epsilon subdivisions,2WW7Y@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit DYD1_k127_4242242_1 240292.Ava_4090 4.729e-63 226.0 COG1278@1|root,COG1278@2|Bacteria,1G5DM@1117|Cyanobacteria,1HMJV@1161|Nostocales 1117|Cyanobacteria K 'Cold-shock' DNA-binding domain - - - - - - - - - - - - CSD,Ribosomal_S30AE DYD1_k127_4243029_5 1231391.AMZF01000003_gene3114 5.419e-27 123.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_4243029_1 1231391.AMZF01000063_gene1102 5.098e-124 417.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_4243029_2 1122915.AUGY01000118_gene6533 1.204e-113 375.0 COG0715@1|root,COG0715@2|Bacteria,1VRJ0@1239|Firmicutes,4HV8W@91061|Bacilli,26U3V@186822|Paenibacillaceae 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - DYD1_k127_4243029_4 1382306.JNIM01000001_gene3579 3.665e-37 147.0 COG3467@1|root,COG3467@2|Bacteria,2G70M@200795|Chloroflexi 200795|Chloroflexi S PFAM pyridoxamine 5'-phosphate oxidase-related - - - - - - - - - - - - Putative_PNPOx DYD1_k127_4243029_0 1047013.AQSP01000121_gene2708 1.247e-173 557.0 COG0323@1|root,COG0323@2|Bacteria 2|Bacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - - - - - - - - - - HATPase_c,HATPase_c_3 DYD1_k127_4243029_3 671143.DAMO_1298 8.832e-58 207.0 COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria 2|Bacteria T COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_4266526_19 866895.HBHAL_3776 0.0005953 46.0 COG3766@1|root,COG3766@2|Bacteria,1V7GI@1239|Firmicutes,4HH0X@91061|Bacilli,3NEXZ@45667|Halobacillus 91061|Bacilli S Domain of Unknown Function (DUF350) - - - ko:K08989 - - - - ko00000 - - - DUF350 DYD1_k127_4266526_11 497965.Cyan7822_0969 3.334e-22 109.0 28J04@1|root,2Z8XE@2|Bacteria,1G4TR@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_4266526_15 443143.GM18_2120 3.111e-17 94.0 2DRUI@1|root,33D4D@2|Bacteria,1NKUT@1224|Proteobacteria,43338@68525|delta/epsilon subdivisions,2WXDX@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4266526_4 697303.Thewi_2044 3.886e-64 231.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,42F3P@68295|Thermoanaerobacterales 186801|Clostridia P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA DYD1_k127_4266526_13 414684.RC1_2914 2.229e-20 100.0 COG0346@1|root,COG0346@2|Bacteria,1RHZT@1224|Proteobacteria,2U9Z4@28211|Alphaproteobacteria,2JSYE@204441|Rhodospirillales 204441|Rhodospirillales E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_2 DYD1_k127_4266526_14 543526.Htur_0597 2.148e-18 90.0 COG4088@1|root,arCOG01041@2157|Archaea,2Y7K4@28890|Euryarchaeota,240T9@183963|Halobacteria 183963|Halobacteria F nucleotide kinase - - 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - AAA_33 DYD1_k127_4266526_8 56780.SYN_00684 3.72e-55 197.0 COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,431WB@68525|delta/epsilon subdivisions 1224|Proteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX DYD1_k127_4266526_7 1331060.RLDS_22000 4.971e-58 210.0 COG1024@1|root,COG1024@2|Bacteria,1MY8F@1224|Proteobacteria,2U9B9@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD1_k127_4266526_12 1454004.AW11_01952 1.752e-21 99.0 COG0071@1|root,COG0071@2|Bacteria,1N0RH@1224|Proteobacteria,2VVUG@28216|Betaproteobacteria 28216|Betaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - - - - - - - - - - HSP20 DYD1_k127_4266526_0 1336243.JAEA01000006_gene314 4.212e-292 919.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2U0IK@28211|Alphaproteobacteria,1JSZW@119045|Methylobacteriaceae 28211|Alphaproteobacteria O Lon protease (S16) C-terminal proteolytic domain MA20_45155 - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD1_k127_4266526_9 452637.Oter_3749 4.997e-55 212.0 COG3267@1|root,COG3267@2|Bacteria,46SXM@74201|Verrucomicrobia,3K91Q@414999|Opitutae 414999|Opitutae U Pfam:Arch_ATPase - - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22 DYD1_k127_4266526_16 1094980.Mpsy_0241 4.696e-14 83.0 arCOG02322@1|root,arCOG02376@1|root,arCOG02322@2157|Archaea,arCOG02376@2157|Archaea,2Y7ZM@28890|Euryarchaeota 2157|Archaea T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9,sCache_3_3 DYD1_k127_4266526_5 1173263.Syn7502_03004 1.095e-63 236.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_4266526_18 402626.Rpic_2267 1.773e-10 73.0 COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,2VR7C@28216|Betaproteobacteria,1K875@119060|Burkholderiaceae 28216|Betaproteobacteria S Peptidoglycan-binding LysM ygaU - - - - - - - - - - - BON,LysM DYD1_k127_4266526_1 1134413.ANNK01000087_gene240 1.032e-99 340.0 COG2223@1|root,COG2223@2|Bacteria,1UJI3@1239|Firmicutes,4IT9X@91061|Bacilli,1ZSAX@1386|Bacillus 91061|Bacilli P MFS_1 like family - - - - - - - - - - - - MFS_1 DYD1_k127_4266526_10 1123368.AUIS01000024_gene953 5.061e-44 166.0 COG2890@1|root,COG2890@2|Bacteria,1MY5I@1224|Proteobacteria,1T26C@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase (PrmA) - - - - - - - - - - - - Methyltransf_31,PrmA DYD1_k127_4266526_6 204669.Acid345_2380 1.319e-58 219.0 COG0477@1|root,COG0477@2|Bacteria,3Y334@57723|Acidobacteria,2JIV9@204432|Acidobacteriia 204432|Acidobacteriia EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 DYD1_k127_4266526_3 1211115.ALIQ01000234_gene4146 3.168e-77 271.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD1_k127_4266526_17 296591.Bpro_0362 1.519e-12 79.0 COG0715@1|root,COG0715@2|Bacteria,1RCBF@1224|Proteobacteria,2VZS3@28216|Betaproteobacteria 28216|Betaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_4266526_2 351607.Acel_0891 7.008e-92 308.0 COG2128@1|root,COG2128@2|Bacteria,2HTUG@201174|Actinobacteria,4EUKU@85013|Frankiales 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - - DYD1_k127_4367512_0 1123504.JQKD01000032_gene4484 8.854e-87 300.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VJW0@28216|Betaproteobacteria,4AJ81@80864|Comamonadaceae 28216|Betaproteobacteria P Rieske [2Fe-2S] domain - - 1.14.13.229,1.14.19.48 ko:K21323 - - - - ko00000,ko01000 - - - Rieske DYD1_k127_4367512_1 69328.PVLB_23030 2.684e-73 264.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases yebA - - - - - - - - - - - OapA,OapA_N,Peptidase_M23 DYD1_k127_4367512_2 1173028.ANKO01000224_gene1260 2.779e-70 252.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 1117|Cyanobacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_4367512_3 717231.Flexsi_0097 3.604e-22 103.0 COG0589@1|root,COG0589@2|Bacteria,2GFI3@200930|Deferribacteres 200930|Deferribacteres T Universal stress protein family - - - - - - - - - - - - Usp DYD1_k127_4371650_3 675635.Psed_3604 1.048e-05 55.0 COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4E35S@85010|Pseudonocardiales 201174|Actinobacteria E Branched-chain amino acid permease - - - - - - - - - - - - AzlC DYD1_k127_4371650_2 266265.Bxe_B2324 5.023e-17 94.0 COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2VKJ4@28216|Betaproteobacteria,1K3BY@119060|Burkholderiaceae 28216|Betaproteobacteria EGP Major facilitator superfamily - - - ko:K05819 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,Sugar_tr DYD1_k127_4371650_1 1403819.BATR01000054_gene1681 6.367e-23 102.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - ko:K11312 - - - - ko00000 - - - Cupin_2,Cupin_3 DYD1_k127_4371650_0 290397.Adeh_3929 6.32e-122 398.0 COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales 28221|Deltaproteobacteria L Belongs to the FPG family - - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD1_k127_4380699_6 234267.Acid_0587 5.057e-35 136.0 COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria 57723|Acidobacteria IQ Phosphate acyltransferases - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase,MFS_1 DYD1_k127_4380699_2 1120980.JQKH01000081_gene858 9.444e-81 282.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2WFHC@28216|Betaproteobacteria,2KSAJ@206351|Neisseriales 206351|Neisseriales P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske DYD1_k127_4380699_7 215803.DB30_6449 2.254e-23 108.0 28RWT@1|root,2ZE8Z@2|Bacteria,1P8WG@1224|Proteobacteria,4386A@68525|delta/epsilon subdivisions,2X3G5@28221|Deltaproteobacteria,2YVYF@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4380699_4 56110.Oscil6304_4866 4.352e-53 198.0 2DBEV@1|root,2Z8UT@2|Bacteria,1G3XJ@1117|Cyanobacteria,1HA4M@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_4380699_1 483219.LILAB_10770 1.296e-127 429.0 COG0318@1|root,COG0318@2|Bacteria,1PH7B@1224|Proteobacteria,42TTG@68525|delta/epsilon subdivisions,2WQEX@28221|Deltaproteobacteria,2YU8V@29|Myxococcales 28221|Deltaproteobacteria IQ GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 DYD1_k127_4380699_3 1120980.JQKH01000081_gene857 2.114e-67 246.0 2BZ6D@1|root,2ZC6J@2|Bacteria,1RBC8@1224|Proteobacteria,2W4E7@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4380699_0 215803.DB30_6451 6.222e-313 985.0 COG4658@1|root,COG4658@2|Bacteria,1QX8H@1224|Proteobacteria,43C1J@68525|delta/epsilon subdivisions,2X7C7@28221|Deltaproteobacteria,2YXH2@29|Myxococcales 28221|Deltaproteobacteria C ASPIC and UnbV - - - - - - - - - - - - NQR2_RnfD_RnfE,UnbV_ASPIC,VCBS DYD1_k127_4380699_5 1173022.Cri9333_2244 5.024e-43 170.0 COG4638@1|root,COG4638@2|Bacteria,1G2UQ@1117|Cyanobacteria,1H8G2@1150|Oscillatoriales 1117|Cyanobacteria P PFAM Rieske 2Fe-2S domain hcaE - - ko:K19982 ko00404,ko01130,map00404,map01130 M00790 R11107 RC01333 ko00000,ko00001,ko00002,ko01000 - - - PaO,Rieske DYD1_k127_4380699_8 497964.CfE428DRAFT_1236 9.216e-23 104.0 2DDJA@1|root,2ZIAT@2|Bacteria 2|Bacteria S P-aminobenzoate N-oxygenase AurF - - - - - - - - - - - - AurF DYD1_k127_4388151_0 671143.DAMO_2812 1.731e-195 615.0 COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria 2|Bacteria C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD1_k127_4388151_8 1298860.AUEM01000001_gene1409 7.831e-16 81.0 2B8RU@1|root,3221R@2|Bacteria,2IT3Z@201174|Actinobacteria,4FSCF@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_4388151_2 1306174.JODP01000002_gene5678 1.394e-81 280.0 COG3384@1|root,COG3384@2|Bacteria,2GNCA@201174|Actinobacteria 201174|Actinobacteria S Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively - - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB DYD1_k127_4388151_3 266779.Meso_2930 5.086e-71 247.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,43IEJ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 DYD1_k127_4388151_7 266779.Meso_2930 4.461e-24 109.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,43IEJ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 DYD1_k127_4388151_1 351607.Acel_0894 1.02e-106 359.0 COG5276@1|root,COG5276@2|Bacteria,2IH2N@201174|Actinobacteria 201174|Actinobacteria S LVIVD repeat - - - - - - - - - - - - LVIVD DYD1_k127_4388151_6 314256.OG2516_16389 3.886e-28 125.0 COG0715@1|root,COG0715@2|Bacteria,1RCBF@1224|Proteobacteria,2U6AN@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - - - - - - - - - - NMT1,NMT1_2 DYD1_k127_4388151_5 1231391.AMZF01000003_gene3114 1.558e-32 140.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_4388151_4 1042326.AZNV01000012_gene1943 5.962e-38 152.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,4BAT1@82115|Rhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_4390252_7 330214.NIDE2664 6.074e-27 112.0 COG2038@1|root,COG2038@2|Bacteria,3J0C9@40117|Nitrospirae 40117|Nitrospirae H Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) cobT - 2.4.2.21 ko:K00768 ko00860,ko01100,map00860,map01100 M00122 R04148 RC00033,RC00063 ko00000,ko00001,ko00002,ko01000 - - - DBI_PRT DYD1_k127_4390252_5 880072.Desac_0474 8.144e-38 151.0 COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,42TXY@68525|delta/epsilon subdivisions,2WQ4J@28221|Deltaproteobacteria,2MQKZ@213462|Syntrophobacterales 28221|Deltaproteobacteria H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate cobS - 2.7.8.26 ko:K02233 ko00860,ko01100,map00860,map01100 M00122 R05223,R11174 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CobS DYD1_k127_4390252_4 335543.Sfum_2741 4.515e-49 192.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WKNZ@28221|Deltaproteobacteria,2MR8B@213462|Syntrophobacterales 28221|Deltaproteobacteria P Periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 DYD1_k127_4390252_2 330214.NIDE2673 7.528e-71 252.0 COG0609@1|root,COG0609@2|Bacteria,3J11Y@40117|Nitrospirae 40117|Nitrospirae P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD DYD1_k127_4390252_3 574087.Acear_0770 3.758e-66 239.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WAET@53433|Halanaerobiales 186801|Clostridia HP PFAM ABC transporter - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran DYD1_k127_4390252_1 1121434.AULY01000009_gene2066 9.131e-92 321.0 COG2410@1|root,COG3359@1|root,COG2410@2|Bacteria,COG3359@2|Bacteria,1R6A2@1224|Proteobacteria,42MVN@68525|delta/epsilon subdivisions,2WK0C@28221|Deltaproteobacteria,2M9EZ@213115|Desulfovibrionales 28221|Deltaproteobacteria L RNase_H superfamily - - - ko:K07502 - - - - ko00000 - - - RNase_H_2 DYD1_k127_4390252_10 673860.AciM339_1124 0.0001442 51.0 COG1102@1|root,arCOG01037@2157|Archaea,2XWPB@28890|Euryarchaeota,3F3AN@33867|unclassified Euryarchaeota 28890|Euryarchaeota F Belongs to the cytidylate kinase family. Type 2 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin2 DYD1_k127_4390252_8 342949.PNA2_1065 1.96e-26 114.0 COG0104@1|root,arCOG04387@2157|Archaea,2XT59@28890|Euryarchaeota,24395@183968|Thermococci 183968|Thermococci F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt DYD1_k127_4390252_9 1121422.AUMW01000012_gene2937 2.514e-07 55.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,263Z4@186807|Peptococcaceae 186801|Clostridia C Acyl-CoA dehydrogenase, N-terminal - - 1.3.99.32 ko:K16173 ko00362,ko01120,map00362,map01120 - R05579 RC00052 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_4390252_6 749414.SBI_03806 1.05e-33 141.0 2CAZG@1|root,2ZBT6@2|Bacteria,2GW3H@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF4276) - - - - - - - - - - - - DUF4276 DYD1_k127_4390252_0 644966.Tmar_0500 1.514e-93 320.0 COG4637@1|root,COG4637@2|Bacteria,1VIP4@1239|Firmicutes,24SCT@186801|Clostridia 186801|Clostridia S PFAM SMC domain protein - - - - - - - - - - - - AAA_15,AAA_21 DYD1_k127_4394248_0 1297742.A176_07148 0.0 1172.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA1 - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC DYD1_k127_4394248_7 316067.Geob_1482 7.349e-17 86.0 COG5512@1|root,COG5512@2|Bacteria,1N6KK@1224|Proteobacteria,42TK4@68525|delta/epsilon subdivisions,2WQQS@28221|Deltaproteobacteria,43VF7@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 DYD1_k127_4394248_4 671143.DAMO_2424 7.519e-60 218.0 COG4123@1|root,COG4123@2|Bacteria,2NPPP@2323|unclassified Bacteria 2|Bacteria S Putative RNA methylase family UPF0020 - - 2.1.1.223 ko:K15460 - - - - ko00000,ko01000,ko03016 - - - MTS,Methyltransf_31 DYD1_k127_4394248_3 330214.NIDE0863 4.532e-87 295.0 COG0767@1|root,COG0767@2|Bacteria,3J0I7@40117|Nitrospirae 40117|Nitrospirae Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD1_k127_4394248_2 671143.DAMO_2220 8.683e-89 301.0 COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria 2|Bacteria Q ABC-type transport system involved in resistance to organic solvents, ATPase component metN - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD1_k127_4394248_5 269799.Gmet_0786 1.163e-40 156.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,43V10@69541|Desulfuromonadales 28221|Deltaproteobacteria Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD1_k127_4394248_6 1121127.JAFA01000017_gene6267 5.323e-21 104.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2VV9X@28216|Betaproteobacteria,1K8N9@119060|Burkholderiaceae 28216|Betaproteobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_4394248_1 1124780.ANNU01000002_gene1614 3.9e-134 436.0 COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,47JS1@768503|Cytophagia 976|Bacteroidetes S PFAM FAD dependent oxidoreductase lhgO - - ko:K15736 - - - - ko00000,ko01000 - - - DAO DYD1_k127_4409912_3 1033734.CAET01000041_gene402 3.708e-50 192.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus 91061|Bacilli C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_4409912_8 296591.Bpro_3359 4.143e-16 83.0 COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria 28216|Betaproteobacteria E ACT domain - - - - - - - - - - - - ACT,ACT_6 DYD1_k127_4409912_6 697282.Mettu_0125 4.417e-17 84.0 2EPVN@1|root,33HG5@2|Bacteria,1NH98@1224|Proteobacteria,1SHUX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4409912_11 1042326.AZNV01000013_gene3378 1.32e-05 49.0 2AFQG@1|root,315SB@2|Bacteria,1PW49@1224|Proteobacteria,2V7AN@28211|Alphaproteobacteria,4BG5U@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2934) - - - - - - - - - - - - DUF2934 DYD1_k127_4409912_9 479434.Sthe_3331 3.661e-14 76.0 2BVHN@1|root,32SWN@2|Bacteria,2G8ZV@200795|Chloroflexi 200795|Chloroflexi S Pfam:DUF385 - - - - - - - - - - - - F420H2_quin_red DYD1_k127_4409912_12 479434.Sthe_3331 0.0005997 43.0 2BVHN@1|root,32SWN@2|Bacteria,2G8ZV@200795|Chloroflexi 200795|Chloroflexi S Pfam:DUF385 - - - - - - - - - - - - F420H2_quin_red DYD1_k127_4409912_7 1532558.JL39_06905 1.021e-16 93.0 COG1840@1|root,COG1840@2|Bacteria,1PGNI@1224|Proteobacteria,2V7J9@28211|Alphaproteobacteria,4B9P8@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11 DYD1_k127_4409912_1 1120949.KB903314_gene302 6.29e-123 416.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria 201174|Actinobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_4409912_4 1120949.KB903314_gene303 3.885e-34 145.0 COG1840@1|root,COG1840@2|Bacteria 2|Bacteria P iron ion homeostasis - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_4409912_2 1463861.JNXE01000003_gene3809 2.614e-92 318.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria 201174|Actinobacteria E Methionine synthase - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_4409912_5 935840.JAEQ01000020_gene2336 8.655e-29 119.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA DYD1_k127_4409912_0 1028801.RG1141_PA00190 1.323e-206 650.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,4BBRG@82115|Rhizobiaceae 28211|Alphaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA DYD1_k127_4409912_10 1265505.ATUG01000002_gene1008 1.716e-08 58.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2MJC5@213118|Desulfobacterales 28221|Deltaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_4413322_7 1202768.JROF01000013_gene891 1.075e-16 90.0 COG0697@1|root,arCOG00272@2157|Archaea,2XUHA@28890|Euryarchaeota,23UY1@183963|Halobacteria 183963|Halobacteria G EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_4413322_0 290397.Adeh_2253 3.527e-223 710.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales 28221|Deltaproteobacteria K ATPase associated with various cellular activities, AAA_5 - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat DYD1_k127_4413322_2 450851.PHZ_c1673 4.709e-92 312.0 2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4413322_9 1194165.CAJF01000018_gene3584 4.813e-10 70.0 COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4FQI1@85023|Microbacteriaceae 201174|Actinobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 DYD1_k127_4413322_5 1123269.NX02_27640 1.285e-64 230.0 COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,2U1VW@28211|Alphaproteobacteria,2K5RK@204457|Sphingomonadales 204457|Sphingomonadales O OsmC-like protein - - - - - - - - - - - - OsmC DYD1_k127_4413322_4 713586.KB900536_gene1206 4.977e-70 245.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase - - - - - - - - - - - - MerC,Methyltransf_31 DYD1_k127_4413322_8 713586.KB900536_gene1206 6.045e-15 76.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase - - - - - - - - - - - - MerC,Methyltransf_31 DYD1_k127_4413322_10 1323663.AROI01000008_gene2627 2.552e-08 64.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria 1224|Proteobacteria C uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center rubA GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575 - - - - - - - - - - Rubredoxin DYD1_k127_4413322_6 443152.MDG893_15295 1.526e-57 213.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_4413322_1 1231391.AMZF01000094_gene122 4.532e-180 580.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_4413322_3 1173027.Mic7113_2967 1.756e-74 264.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 2|Bacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_4423657_1 1116369.KB890024_gene689 3.499e-29 117.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Recombinase zinc beta ribbon domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom DYD1_k127_4423657_0 1038860.AXAP01000007_gene6037 2.82e-99 335.0 COG0189@1|root,COG0189@2|Bacteria,1NX9V@1224|Proteobacteria,2TU7A@28211|Alphaproteobacteria,3JSIX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria HJ ligase activity - - - - - - - - - - - - - DYD1_k127_4464894_0 1232410.KI421425_gene1521 9.912e-194 617.0 COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,43SDT@69541|Desulfuromonadales 28221|Deltaproteobacteria A Domain of unknown function (DUF3552) rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 DYD1_k127_4464894_9 1121439.dsat_1006 8.893e-35 141.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,42TZ2@68525|delta/epsilon subdivisions,2WQJG@28221|Deltaproteobacteria,2MC1P@213115|Desulfovibrionales 28221|Deltaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig DYD1_k127_4464894_10 1408254.T458_08190 6.914e-12 69.0 COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA DYD1_k127_4464894_11 1158762.KB898055_gene12 1.508e-09 65.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - CopD,Cytochrome_CBB3 DYD1_k127_4464894_7 1232410.KI421428_gene1010 2.066e-39 150.0 COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,42SID@68525|delta/epsilon subdivisions,2WQ86@28221|Deltaproteobacteria,43SGS@69541|Desulfuromonadales 28221|Deltaproteobacteria K nickel-responsive regulator nikR GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K07722 - - - - ko00000,ko03000 - - - NikR_C,RHH_1 DYD1_k127_4464894_6 1120972.AUMH01000002_gene2753 8.409e-58 217.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_4464894_2 316274.Haur_2846 9.33e-109 363.0 COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,37738@32061|Chloroflexia 200795|Chloroflexi P Belongs to the bacterial solute-binding protein 9 family - - - ko:K02077,ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA DYD1_k127_4464894_4 316274.Haur_2845 5.693e-75 261.0 COG1121@1|root,COG1121@2|Bacteria,2G5WQ@200795|Chloroflexi,374U1@32061|Chloroflexia 200795|Chloroflexi P PFAM ABC transporter related - - - ko:K09817 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC_tran DYD1_k127_4464894_3 316274.Haur_2844 5.71e-80 275.0 COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,376AB@32061|Chloroflexia 200795|Chloroflexi P ABC-3 protein - - - ko:K09816,ko:K09819 ko02010,map02010 M00242,M00243 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 DYD1_k127_4464894_8 420324.KI912061_gene6195 4.986e-36 144.0 COG1999@1|root,COG1999@2|Bacteria,1N6WC@1224|Proteobacteria,2VFHX@28211|Alphaproteobacteria 1224|Proteobacteria S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - AhpC-TSA,SCO1-SenC DYD1_k127_4464894_5 211165.AJLN01000104_gene6534 4.427e-60 213.0 COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria,1JJCS@1189|Stigonemataceae 1117|Cyanobacteria J Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD1_k127_4464894_13 237368.SCABRO_03439 9.259e-05 53.0 28WSA@1|root,2ZIS0@2|Bacteria,2J4NA@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - DYD1_k127_4464894_1 748247.AZKH_2773 3.135e-121 391.0 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2VK8F@28216|Betaproteobacteria,2KWZJ@206389|Rhodocyclales 206389|Rhodocyclales O C-terminal domain of 1-Cys peroxiredoxin - - - - - - - - - - - - 1-cysPrx_C,AhpC-TSA DYD1_k127_4467027_3 215803.DB30_1489 1.779e-14 85.0 COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1QX4Q@1224|Proteobacteria,4379A@68525|delta/epsilon subdivisions,2X97U@28221|Deltaproteobacteria,2YXK6@29|Myxococcales 28221|Deltaproteobacteria T PAS fold - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_3 DYD1_k127_4467027_2 644968.DFW101_2001 3.779e-37 155.0 COG4191@1|root,COG4191@2|Bacteria,1RI33@1224|Proteobacteria,42SUG@68525|delta/epsilon subdivisions,2WP3A@28221|Deltaproteobacteria,2M7VI@213115|Desulfovibrionales 28221|Deltaproteobacteria T signal transduction histidine kinase bamV - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1 DYD1_k127_4467027_0 671143.DAMO_3115 9.216e-103 346.0 COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria 2|Bacteria O smart pdz dhr glgf degP GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 DYD1_k127_4467027_1 1095769.CAHF01000017_gene30 4.679e-38 144.0 COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,2VIYW@28216|Betaproteobacteria,473R6@75682|Oxalobacteraceae 28216|Betaproteobacteria O Glutathione S-transferase, C-terminal domain gstP - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_3 DYD1_k127_4490781_3 216816.GS08_06310 2.756e-10 63.0 COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZCX@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_4490781_1 269799.Gmet_1736 6.607e-179 572.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,43T78@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c DYD1_k127_4490781_0 1047013.AQSP01000138_gene1021 1.557e-290 901.0 COG0008@1|root,COG0008@2|Bacteria,2NNRW@2323|unclassified Bacteria 2|Bacteria J tRNA synthetases class I (E and Q), anti-codon binding domain glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C DYD1_k127_4490781_2 768670.Calni_0340 1.17e-41 168.0 COG2067@1|root,COG2067@2|Bacteria,2GFPR@200930|Deferribacteres 200930|Deferribacteres I PFAM membrane protein involved in aromatic hydrocarbon degradation - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X DYD1_k127_4517874_1 583345.Mmol_1395 8.316e-110 366.0 COG2204@1|root,COG4963@1|root,COG2204@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2VNYQ@28216|Betaproteobacteria,2KNDN@206350|Nitrosomonadales 206350|Nitrosomonadales D Cellulose biosynthesis protein BcsQ - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,Response_reg DYD1_k127_4517874_0 748280.NH8B_2376 2.221e-201 636.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria,2KTWA@206351|Neisseriales 206351|Neisseriales U Type II/IV secretion system protein - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE DYD1_k127_4517874_2 1502770.JQMG01000001_gene1736 2.033e-104 348.0 COG4965@1|root,COG4965@2|Bacteria,1RDNH@1224|Proteobacteria,2VRA2@28216|Betaproteobacteria,2KMPP@206350|Nitrosomonadales 206350|Nitrosomonadales U Type II secretion system (T2SS), protein F - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF DYD1_k127_4517874_3 1288494.EBAPG3_26670 2.871e-98 330.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2VIA4@28216|Betaproteobacteria,3742J@32003|Nitrosomonadales 28216|Betaproteobacteria NU Type II secretion system (T2SS), protein F tadC - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF DYD1_k127_4517874_5 1288494.EBAPG3_26680 8.938e-52 203.0 COG0457@1|root,COG0457@2|Bacteria,1RJT4@1224|Proteobacteria,2VSH2@28216|Betaproteobacteria,373XQ@32003|Nitrosomonadales 28216|Betaproteobacteria S LytR cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C,TPR_1,TPR_2,TPR_8 DYD1_k127_4517874_4 1122603.ATVI01000012_gene1206 8.935e-94 331.0 COG1402@1|root,COG3000@1|root,COG1402@2|Bacteria,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1X7BZ@135614|Xanthomonadales 135614|Xanthomonadales I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase DYD1_k127_4517874_6 543728.Vapar_0595 1.317e-22 99.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VTZ8@28216|Betaproteobacteria,4AF1S@80864|Comamonadaceae 28216|Betaproteobacteria L PFAM Transposase IS3 - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1 DYD1_k127_4533814_8 177439.DP2631 0.0003547 46.0 COG0318@1|root,COG0318@2|Bacteria,1R5I6@1224|Proteobacteria,42MKC@68525|delta/epsilon subdivisions,2WK3U@28221|Deltaproteobacteria,2MI82@213118|Desulfobacterales 28221|Deltaproteobacteria IQ AMP-binding enzyme - - 6.1.3.1 ko:K22319 - - - - ko00000,ko01000 - - - AMP-binding DYD1_k127_4533814_3 671143.DAMO_1116 3.333e-58 214.0 COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria 2|Bacteria M Mannose-6-phosphate isomerase manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase DYD1_k127_4533814_5 861299.J421_1875 5.613e-48 178.0 COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - ko:K11477 - - - - ko00000 - - - Cupin_2,Haem_degrading DYD1_k127_4533814_1 861299.J421_1875 9.557e-78 269.0 COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - ko:K11477 - - - - ko00000 - - - Cupin_2,Haem_degrading DYD1_k127_4533814_0 861299.J421_1876 5.032e-200 642.0 COG3386@1|root,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD1_k127_4533814_4 63737.Npun_F2199 1.666e-49 181.0 COG4828@1|root,COG4828@2|Bacteria,1G5WZ@1117|Cyanobacteria,1HQ87@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function (DUF1622) - - - - - - - - - - - - DUF1622 DYD1_k127_4533814_2 118173.KB235914_gene2349 2.206e-77 263.0 COG0431@1|root,COG0431@2|Bacteria,1G3AZ@1117|Cyanobacteria,1HAU3@1150|Oscillatoriales 1117|Cyanobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red DYD1_k127_4533814_6 593750.Metfor_1696 2.946e-28 122.0 COG3548@1|root,arCOG04887@2157|Archaea,2XUMU@28890|Euryarchaeota 28890|Euryarchaeota S integral membrane protein - - - - - - - - - - - - DUF1211 DYD1_k127_4533814_7 1089547.KB913013_gene1907 9.598e-06 50.0 COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,47KMQ@768503|Cytophagia 976|Bacteroidetes G PFAM SMP-30 Gluconolaconase - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD1_k127_4566144_0 765420.OSCT_3114 2.861e-219 695.0 COG1132@1|root,COG1132@2|Bacteria,2G7QD@200795|Chloroflexi,376IN@32061|Chloroflexia 32061|Chloroflexia P PFAM ABC transporter related - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD1_k127_4571999_0 671143.DAMO_2862 2.104e-60 213.0 COG0242@1|root,COG0242@2|Bacteria 2|Bacteria J peptide deformylase activity def2 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD1_k127_4571999_3 240015.ACP_2978 4.226e-28 118.0 COG0494@1|root,COG0494@2|Bacteria,3Y55X@57723|Acidobacteria,2JN43@204432|Acidobacteriia 204432|Acidobacteriia L NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX DYD1_k127_4571999_1 330214.NIDE3738 2.981e-44 168.0 COG0741@1|root,COG0741@2|Bacteria,3J19T@40117|Nitrospirae 40117|Nitrospirae M Transglycosylase SLT domain - - - - - - - - - - - - SLT DYD1_k127_4571999_2 880072.Desac_2498 6.654e-42 160.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,2MQNN@213462|Syntrophobacterales 28221|Deltaproteobacteria I CDP-alcohol phosphatidyltransferase pgsA - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD1_k127_4571999_4 290398.Csal_1776 2.012e-06 55.0 COG0859@1|root,COG0859@2|Bacteria,1N2DA@1224|Proteobacteria,1SBNA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M glycosyl transferase family - - - - - - - - - - - - Glyco_transf_9 DYD1_k127_458628_2 1408254.T458_17235 2.554e-62 218.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26Q92@186822|Paenibacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim DYD1_k127_458628_0 760568.Desku_1315 1.845e-111 376.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,2614J@186807|Peptococcaceae 186801|Clostridia J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB DYD1_k127_458628_1 330214.NIDE0395 1.879e-87 299.0 COG0223@1|root,COG0223@2|Bacteria,3J0GW@40117|Nitrospirae 40117|Nitrospirae J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD1_k127_458628_3 1267534.KB906754_gene2789 0.0002298 44.0 COG0242@1|root,COG0242@2|Bacteria,3Y4DG@57723|Acidobacteria,2JJ27@204432|Acidobacteriia 204432|Acidobacteriia J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD1_k127_4672695_2 264198.Reut_B3913 6.01e-28 117.0 COG4274@1|root,COG4274@2|Bacteria,1RHJ3@1224|Proteobacteria,2VXBZ@28216|Betaproteobacteria,1KG10@119060|Burkholderiaceae 28216|Betaproteobacteria S GYD domain - - - - - - - - - - - - GYD DYD1_k127_4672695_0 1267534.KB906759_gene1728 3.45e-252 791.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia 2|Bacteria C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg porA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - iLJ478.TM1164 PFOR_II,POR,POR_N,Transketolase_C DYD1_k127_4672695_1 1267534.KB906759_gene1729 3.256e-119 391.0 COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia 2|Bacteria C Pyruvate ferredoxin oxidoreductase beta subunit C terminal porB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C DYD1_k127_4681590_2 357808.RoseRS_3609 6.791e-46 169.0 COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi 200795|Chloroflexi P PFAM sodium calcium exchanger membrane region - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD1_k127_4681590_0 472759.Nhal_1697 2.171e-179 570.0 COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,1S04A@1236|Gammaproteobacteria 1224|Proteobacteria M glycosyl transferase group 1 - - 2.4.1.245 ko:K13057 ko00500,ko01100,map00500,map01100 - R08946,R10525,R11306 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000 - GT4 - Glycos_transf_1 DYD1_k127_4681590_4 242159.ABO94377 6.457e-32 133.0 COG2453@1|root,KOG1716@2759|Eukaryota,37JIZ@33090|Viridiplantae,34I0B@3041|Chlorophyta 3041|Chlorophyta V Dual specificity phosphatase, catalytic domain - - 3.1.3.16,3.1.3.48 ko:K14165 - - - - ko00000,ko01000,ko01009 - - - DSPc DYD1_k127_4681590_3 517418.Ctha_2397 3.706e-39 156.0 COG0428@1|root,COG0428@2|Bacteria 2|Bacteria P transporter - - - ko:K11021,ko:K16267 - - - - ko00000,ko02000,ko02042 2.A.5.4.11 - - Zip DYD1_k127_4681590_1 1121033.AUCF01000010_gene4489 5.474e-91 311.0 COG1236@1|root,COG1236@2|Bacteria,1RBYT@1224|Proteobacteria,2U2M0@28211|Alphaproteobacteria,2JWJY@204441|Rhodospirillales 204441|Rhodospirillales J metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain - - - - - - - - - - - - Lactamase_B_2 DYD1_k127_4684114_2 469383.Cwoe_4099 5.393e-88 302.0 COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria 201174|Actinobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_4684114_4 1041522.MCOL_V209005 1.139e-57 214.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_4684114_5 671143.DAMO_0384 2.404e-23 104.0 2DD3Z@1|root,2ZGDH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4684114_6 378806.STAUR_6277 1.717e-14 81.0 COG1329@1|root,COG1329@2|Bacteria,1PD80@1224|Proteobacteria,438VF@68525|delta/epsilon subdivisions,2X5V4@28221|Deltaproteobacteria,2YXWM@29|Myxococcales 28221|Deltaproteobacteria K DNA binding domain with preference for A/T rich regions - - - - - - - - - - - - CarD_CdnL_TRCF DYD1_k127_4684114_3 56780.SYN_02762 4.557e-76 269.0 COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - - - - - - - - - - - DisA_N,YbbR DYD1_k127_4684114_0 1382356.JQMP01000004_gene485 1.344e-297 925.0 COG0366@1|root,COG0366@2|Bacteria,2G89J@200795|Chloroflexi,27XYW@189775|Thermomicrobia 189775|Thermomicrobia G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 DYD1_k127_4684114_1 326427.Cagg_2090 8.153e-105 342.0 COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,377XJ@32061|Chloroflexia 32061|Chloroflexia G SMART alpha amylase, catalytic sub domain - - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C DYD1_k127_4686087_18 521011.Mpal_0423 7.257e-10 68.0 COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia 2157|Archaea S PFAM NHL repeat containing protein - - - - - - - - - - - - CBM_6,HemolysinCabind,Kelch_4,NHL,PKD DYD1_k127_4686087_10 243159.AFE_1372 9.958e-33 132.0 COG3177@1|root,COG3177@2|Bacteria,1NB0K@1224|Proteobacteria,1S0F4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Filamentation induced by cAMP protein - - - - - - - - - - - - Fic DYD1_k127_4686087_15 671143.DAMO_3098 2.577e-25 109.0 COG2331@1|root,COG2331@2|Bacteria,2NRJX@2323|unclassified Bacteria 2|Bacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 DYD1_k127_4686087_4 1380394.JADL01000003_gene4948 5.396e-75 258.0 COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VEZC@28211|Alphaproteobacteria,2JU3P@204441|Rhodospirillales 204441|Rhodospirillales O Glutathione S-transferase, N-terminal domain - - - - - - - - - - - - GST_C,GST_N DYD1_k127_4686087_19 4924.XP_001383521.1 4.046e-09 68.0 COG0715@1|root,2QQ87@2759|Eukaryota,38GXI@33154|Opisthokonta,3NUEB@4751|Fungi,3QNCT@4890|Ascomycota,3RR1Y@4891|Saccharomycetes,47ATR@766764|Debaryomycetaceae 4751|Fungi H NMT1/THI5 like nmt1 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016853,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0070283,GO:0070284,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K18278 ko00730,ko01100,map00730,map01100 - R10686 - ko00000,ko00001 - - - NMT1 DYD1_k127_4686087_22 1449044.JMLE01000018_gene1661 4.089e-05 53.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_4686087_13 1223523.H340_00889 2.573e-27 121.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria 201174|Actinobacteria S Pfam Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_4686087_23 1110502.TMO_0012 0.0002875 51.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_4686087_5 1157708.KB907450_gene5321 5.631e-70 245.0 COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2VJ7W@28216|Betaproteobacteria,4ADUX@80864|Comamonadaceae 28216|Betaproteobacteria P extracellular solute-binding protein, family 1 - - 5.3.3.7 ko:K22003 ko00660,map00660 - R02244 RC00668 ko00000,ko00001,ko01000 - - - SBP_bac_11 DYD1_k127_4686087_17 56780.SYN_02481 6.303e-13 70.0 COG0135@1|root,COG0135@2|Bacteria,1RA5Q@1224|Proteobacteria,42T4S@68525|delta/epsilon subdivisions,2WP9V@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Belongs to the TrpF family - - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI DYD1_k127_4686087_0 1128421.JAGA01000004_gene2558 3.549e-112 376.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_4686087_21 284031.JNXD01000025_gene367 2.044e-06 59.0 COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_4686087_20 227882.SAV_5962 1.147e-06 59.0 COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_4686087_14 1182590.BN5_03552 4.92e-26 118.0 COG0697@1|root,COG0697@2|Bacteria,1R6SK@1224|Proteobacteria 1224|Proteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD1_k127_4686087_1 146922.JOFU01000020_gene2529 4.537e-95 323.0 COG2355@1|root,COG2355@2|Bacteria 2|Bacteria E Zn-dependent dipeptidase, microsomal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Dickkopf_N,Peptidase_M19,Ricin_B_lectin DYD1_k127_4686087_7 570268.ANBB01000017_gene3847 5.233e-42 173.0 COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria 201174|Actinobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 DYD1_k127_4686087_9 1226994.AMZB01000124_gene2969 7.982e-39 151.0 COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria,1S2F9@1236|Gammaproteobacteria,1YGC1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S LexA-binding, inner membrane-associated putative hydrolase ybcI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07038 - - - - ko00000 - - - YdjM DYD1_k127_4686087_12 670292.JH26_14835 1.551e-27 119.0 2EAFX@1|root,32G8D@2|Bacteria,1RJFV@1224|Proteobacteria,2U9DS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4686087_6 1095769.CAHF01000010_gene1111 1.259e-62 217.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2VSQ1@28216|Betaproteobacteria,477AF@75682|Oxalobacteraceae 28216|Betaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD1_k127_4686087_16 1463934.JOCF01000036_gene2270 2.993e-16 89.0 COG0596@1|root,COG0596@2|Bacteria,2H1QB@201174|Actinobacteria 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_4686087_2 1192034.CAP_6251 2.188e-92 316.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_4686087_3 350058.Mvan_1001 5.993e-82 287.0 COG4638@1|root,COG4638@2|Bacteria,2GKMV@201174|Actinobacteria,236I0@1762|Mycobacteriaceae 201174|Actinobacteria P Rieske [2Fe-2S] domain vanA - - ko:K19982 ko00404,ko01130,map00404,map01130 M00790 R11107 RC01333 ko00000,ko00001,ko00002,ko01000 - - - Rieske DYD1_k127_4686087_11 762376.AXYL_00250 1.791e-29 124.0 COG1028@1|root,COG1028@2|Bacteria,1MX30@1224|Proteobacteria,2VHW0@28216|Betaproteobacteria,3T5AW@506|Alcaligenaceae 28216|Betaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 DYD1_k127_4687399_1 1121904.ARBP01000005_gene4736 1.13e-268 842.0 COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,47KWW@768503|Cytophagia 976|Bacteroidetes E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N DYD1_k127_4687399_3 1232410.KI421413_gene941 2.531e-161 519.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,43RY0@69541|Desulfuromonadales 28221|Deltaproteobacteria L MgsA AAA+ ATPase C terminal rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N DYD1_k127_4687399_17 1242864.D187_005181 4.588e-10 66.0 COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2YVIX@29|Myxococcales 28221|Deltaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin DYD1_k127_4687399_9 555088.DealDRAFT_1980 3.265e-42 158.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,42K07@68298|Syntrophomonadaceae 186801|Clostridia J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 DYD1_k127_4687399_6 639282.DEFDS_0251 1.783e-133 441.0 COG0336@1|root,COG4752@1|root,COG0336@2|Bacteria,COG4752@2|Bacteria,2GEM4@200930|Deferribacteres 200930|Deferribacteres J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - Methyltrn_RNA_4,tRNA_m1G_MT DYD1_k127_4687399_15 909663.KI867150_gene966 1.379e-20 98.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,42TGI@68525|delta/epsilon subdivisions,2WQJU@28221|Deltaproteobacteria,2MQMB@213462|Syntrophobacterales 28221|Deltaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM DYD1_k127_4687399_13 795359.TOPB45_0707 2.377e-24 104.0 COG1837@1|root,COG1837@2|Bacteria,2GI1Q@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S Belongs to the UPF0109 family - - - ko:K06960 - - - - ko00000 - - - KH_4 DYD1_k127_4687399_14 1514668.JOOA01000002_gene2288 2.7e-23 101.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3WJSQ@541000|Ruminococcaceae 186801|Clostridia J Belongs to the bacterial ribosomal protein bS16 family rpsP - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 DYD1_k127_4687399_4 690850.Desaf_0510 9.75e-152 491.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2M8JZ@213115|Desulfovibrionales 28221|Deltaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB DYD1_k127_4687399_0 290397.Adeh_3594 5.129e-273 848.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales 28221|Deltaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD1_k127_4687399_10 404589.Anae109_3714 3.851e-41 154.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales 28221|Deltaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD1_k127_4687399_16 404380.Gbem_0247 5.823e-18 88.0 COG2952@1|root,COG2952@2|Bacteria,1NKWU@1224|Proteobacteria,42XJT@68525|delta/epsilon subdivisions,2WSNN@28221|Deltaproteobacteria,43SST@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF507) - - - - - - - - - - - - DUF507 DYD1_k127_4687399_18 243231.GSU3335 2.722e-06 53.0 COG2952@1|root,COG2952@2|Bacteria,1P5SW@1224|Proteobacteria,432F2@68525|delta/epsilon subdivisions,2WXGJ@28221|Deltaproteobacteria,43VR0@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF507) - - - - - - - - - - - - DUF507 DYD1_k127_4687399_8 1131269.AQVV01000004_gene588 5.151e-62 225.0 COG1619@1|root,COG1619@2|Bacteria 2|Bacteria V carboxypeptidase activity - - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 DYD1_k127_4687399_7 1499967.BAYZ01000139_gene140 4.139e-90 310.0 COG1680@1|root,COG1680@2|Bacteria,2NPA1@2323|unclassified Bacteria 2|Bacteria V Beta-lactamase nagA - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C DYD1_k127_4687399_5 880072.Desac_0506 6.987e-142 464.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2MR1Q@213462|Syntrophobacterales 28221|Deltaproteobacteria M Mur ligase family, catalytic domain mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD1_k127_4687399_19 1121918.ARWE01000001_gene235 4.522e-05 49.0 COG3350@1|root,COG3350@2|Bacteria 2|Bacteria T monooxygenase activity tmoA GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 ko:K00688,ko:K15760,ko:K16157,ko:K16242,ko:K18223,ko:K22353,ko:K22357 ko00361,ko00362,ko00500,ko00623,ko00625,ko00640,ko00680,ko01100,ko01110,ko01120,ko01200,ko01220,ko02026,ko04217,ko04910,ko04922,ko04931,map00361,map00362,map00500,map00623,map00625,map00640,map00680,map01100,map01110,map01120,map01200,map01220,map02026,map04217,map04910,map04922,map04931 M00174,M00538,M00548 R01142,R02111,R02550,R03560,R03562,R03608,R05444,R05666,R10042,R10043,R10702,R11901 RC00046,RC00173,RC00269,RC00490,RC01383,RC03249 ko00000,ko00001,ko00002,ko01000 - GT35 - Phenol_Hydrox,YHS DYD1_k127_4687399_11 1131269.AQVV01000045_gene1583 1.11e-37 151.0 COG0801@1|root,COG0801@2|Bacteria 2|Bacteria H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity folK - 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - iLJ478.TM0041 FolB,HPPK DYD1_k127_4687399_2 330214.NIDE0503 1.035e-161 517.0 COG0436@1|root,COG0436@2|Bacteria,3J0G2@40117|Nitrospirae 40117|Nitrospirae E Aminotransferase class I and II - - 2.6.1.83 ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_4687399_12 56780.SYN_01764 2.088e-26 115.0 COG3688@1|root,COG3688@2|Bacteria,1N1NF@1224|Proteobacteria,42UMH@68525|delta/epsilon subdivisions,2WQJ5@28221|Deltaproteobacteria,2MSA5@213462|Syntrophobacterales 28221|Deltaproteobacteria S YacP-like NYN domain - - - ko:K06962 - - - - ko00000 - - - NYN_YacP DYD1_k127_4698369_0 909663.KI867150_gene2871 3.923e-143 469.0 COG3039@1|root,COG3039@2|Bacteria,1QY2X@1224|Proteobacteria 1224|Proteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_6 DYD1_k127_4698369_3 99598.Cal7507_5447 6.668e-30 122.0 COG3657@1|root,COG3657@2|Bacteria,1G6YT@1117|Cyanobacteria,1HP5G@1161|Nostocales 1117|Cyanobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 DYD1_k127_4698369_1 443152.MDG893_15295 2.991e-53 203.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_4698369_2 1173263.Syn7502_03004 1.1e-40 164.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_4698369_5 1285586.H131_08718 8.426e-10 60.0 COG0665@1|root,COG0665@2|Bacteria,1TRYK@1239|Firmicutes,4HAM4@91061|Bacilli,3IXK7@400634|Lysinibacillus 91061|Bacilli E FAD dependent oxidoreductase solA - 1.5.3.1 ko:K00301,ko:K02846 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO DYD1_k127_4701848_4 1038859.AXAU01000026_gene2332 1.82e-74 256.0 COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2TRX5@28211|Alphaproteobacteria,3JRYA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N DYD1_k127_4701848_3 504832.OCAR_7524 2.071e-133 431.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRS8@28211|Alphaproteobacteria,3JS1M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component nikB - - ko:K02033,ko:K15585 ko02010,ko02024,map02010,map02024 M00239,M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD1_k127_4701848_0 504832.OCAR_7523 1.842e-179 581.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria,3JQQ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_4701848_1 926550.CLDAP_11110 1.071e-138 450.0 COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi 200795|Chloroflexi P Belongs to the ABC transporter superfamily - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_4701848_2 1038859.AXAU01000026_gene2328 9.386e-138 445.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,3JRF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_4701848_5 269799.Gmet_0887 1.684e-28 129.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,43TBY@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 39 arnT - - - - - - - - - - - PMT,PMT_2 DYD1_k127_4711355_3 1123376.AUIU01000012_gene1394 1.353e-61 216.0 COG0253@1|root,COG0253@2|Bacteria,3J0JV@40117|Nitrospirae 40117|Nitrospirae E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase DYD1_k127_4711355_2 338963.Pcar_2420 1.449e-175 559.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,43U09@69541|Desulfuromonadales 28221|Deltaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC DYD1_k127_4711355_4 1167006.UWK_00680 6.48e-10 65.0 COG4733@1|root,COG4733@2|Bacteria,1NKYK@1224|Proteobacteria,42XNS@68525|delta/epsilon subdivisions,2WSIS@28221|Deltaproteobacteria,2MM8J@213118|Desulfobacterales 28221|Deltaproteobacteria S cellulase activity - - - - - - - - - - - - - DYD1_k127_4711355_1 338963.Pcar_2418 6.107e-178 569.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,43RY2@69541|Desulfuromonadales 28221|Deltaproteobacteria E Argininosuccinate lyase C-terminal argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1,NUDIX DYD1_k127_4711355_0 671143.DAMO_0085 9.394e-183 577.0 COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria 2|Bacteria E Arginosuccinate synthase argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN678.argG,iSB619.SA_RS04675 Arginosuc_synth DYD1_k127_4717847_3 1267533.KB906734_gene3652 2.701e-34 135.0 COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia 204432|Acidobacteriia I Enoyl-CoA hydratase/isomerase - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_4717847_1 1121430.JMLG01000002_gene1079 2.08e-55 206.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae 186801|Clostridia I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_4717847_4 1499685.CCFJ01000046_gene3118 0.0001541 48.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZM4E@1386|Bacillus 91061|Bacilli IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD1_k127_4717847_2 402881.Plav_0389 6.045e-49 186.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2TU8W@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_4717847_0 316067.Geob_0958 5.805e-138 455.0 COG1502@1|root,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,42Z8A@68525|delta/epsilon subdivisions,2WU56@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Phospholipase D. Active site motifs. - - - - - - - - - - - - PLDc,PLDc_2 DYD1_k127_4733816_5 382464.ABSI01000011_gene2473 6.809e-12 69.0 COG0028@1|root,COG1404@1|root,COG2885@1|root,COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3507@1|root,COG4733@1|root,COG4935@1|root,COG5295@1|root,COG0028@2|Bacteria,COG1404@2|Bacteria,COG2885@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3507@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,COG5295@2|Bacteria,46W6Z@74201|Verrucomicrobia 2|Bacteria GMOU Fibronectin type 3 domain - - 3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3 ko:K01179,ko:K01361,ko:K01637,ko:K01729,ko:K09942,ko:K20276 ko00051,ko00500,ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00051,map00500,map00630,map01100,map01110,map01120,map01200,map02024 M00012 R00479,R03706,R06200,R11307,R11308 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - GH5,GH9 - fn3 DYD1_k127_4733816_0 631362.Thi970DRAFT_01110 1.537e-107 370.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,1RXY8@1236|Gammaproteobacteria,1WW0M@135613|Chromatiales 135613|Chromatiales M PFAM lipopolysaccharide biosynthesis - - - - - - - - - - - - Wzz DYD1_k127_4733816_2 1163617.SCD_n01329 3.736e-67 239.0 COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VN0C@28216|Betaproteobacteria 28216|Betaproteobacteria D Capsular exopolysaccharide family epsG - 2.7.10.1 ko:K08252,ko:K16692 - - - - ko00000,ko01000,ko01001 - - - AAA_31,CbiA,GNVR,Wzz DYD1_k127_4733816_3 1121456.ATVA01000018_gene381 9.647e-40 165.0 2AIHM@1|root,318ZH@2|Bacteria,1Q18U@1224|Proteobacteria,435X0@68525|delta/epsilon subdivisions,2X0DE@28221|Deltaproteobacteria,2MBWW@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4733816_1 118168.MC7420_1754 4.817e-97 336.0 COG3379@1|root,COG3379@2|Bacteria,1G44K@1117|Cyanobacteria,1HD9A@1150|Oscillatoriales 1117|Cyanobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest DYD1_k127_4733816_4 406124.ACPC01000020_gene3915 9.081e-34 141.0 COG0438@1|root,COG0438@2|Bacteria,1UI6T@1239|Firmicutes,4ISFV@91061|Bacilli,1ZDUG@1386|Bacillus 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_4743050_5 1192034.CAP_6251 6.86e-67 241.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_4743050_6 395964.KE386496_gene88 1.755e-40 166.0 COG0642@1|root,COG2972@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,1NRP8@1224|Proteobacteria,2TQWE@28211|Alphaproteobacteria,3NACX@45404|Beijerinckiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain MA20_23075 - - ko:K20971 ko02025,map02025 - - - ko00000,ko00001,ko01001,ko02022 - - - HATPase_c,HisKA,Response_reg DYD1_k127_4743050_0 697282.Mettu_3502 1.771e-134 447.0 COG3290@1|root,COG3447@1|root,COG3614@1|root,COG3920@1|root,COG3290@2|Bacteria,COG3447@2|Bacteria,COG3614@2|Bacteria,COG3920@2|Bacteria,1PGPR@1224|Proteobacteria,1RX1U@1236|Gammaproteobacteria,1XGJY@135618|Methylococcales 135618|Methylococcales T Histidine kinase - - - - - - - - - - - - HisKA_2 DYD1_k127_4743050_7 1961.JOAK01000003_gene1455 4.441e-40 171.0 COG2208@1|root,COG4251@1|root,COG2208@2|Bacteria,COG4251@2|Bacteria,2GK8P@201174|Actinobacteria 201174|Actinobacteria T protein phosphatase 2C domain protein - - - - - - - - - - - - GAF_2,HATPase_c_2,PAS,PAS_4,PAS_9,SpoIIE DYD1_k127_4743050_3 909663.KI867150_gene1026 6.038e-70 265.0 COG2202@1|root,COG3829@1|root,COG4585@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,1N0Y7@1224|Proteobacteria 1224|Proteobacteria T PFAM ATP-binding region - - - - - - - - - - - - HATPase_c,HisKA_3,MASE1,PAS DYD1_k127_4743050_4 909663.KI867150_gene1086 6.297e-70 244.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales 28221|Deltaproteobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_4743050_2 330214.NIDE0217 1.548e-117 397.0 COG2831@1|root,COG2831@2|Bacteria 2|Bacteria U hemolysin activation secretion protein - - - - - - - - - - - - POTRA_2,ShlB DYD1_k127_4743050_1 156889.Mmc1_0780 3.405e-131 458.0 COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2TTVB@28211|Alphaproteobacteria 28211|Alphaproteobacteria U TIGRFAM filamentous haemagglutinin family outer membrane protein - - - - - - - - - - - - ESPR,FG-GAP_2,Glug,Haemagg_act DYD1_k127_4752283_6 639282.DEFDS_1602 9.599e-22 100.0 COG0741@1|root,COG0741@2|Bacteria,2GFMV@200930|Deferribacteres 200930|Deferribacteres M Transglycosylase SLT domain - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT DYD1_k127_4752283_3 671143.DAMO_2217 1.643e-44 168.0 COG2854@1|root,COG2854@2|Bacteria 2|Bacteria Q intermembrane phospholipid transfer - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD1_k127_4752283_9 1150600.ADIARSV_3090 5.823e-05 51.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1IQFC@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the ompA family yiaD - - - - - - - - - - - Gly-zipper_Omp,OmpA DYD1_k127_4752283_2 927677.ALVU02000001_gene2961 7.763e-45 169.0 COG0116@1|root,COG0116@2|Bacteria,1GQF9@1117|Cyanobacteria 1117|Cyanobacteria L Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD1_k127_4752283_7 292564.Cyagr_0240 3.615e-13 72.0 COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1G0DH@1117|Cyanobacteria 1117|Cyanobacteria S conserved protein (DUF2081) - - - - - - - - - - - - DUF262 DYD1_k127_4752283_8 1191523.MROS_2770 5.947e-06 51.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding usp-3 - - - - - - - - - - - Usp DYD1_k127_4752283_5 227882.SAV_5962 2.836e-24 106.0 COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_4752283_0 266117.Rxyl_3133 3.356e-116 391.0 COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4CS7R@84995|Rubrobacteria 84995|Rubrobacteria C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_binding_2 DYD1_k127_4752283_4 1500259.JQLD01000010_gene4824 1.858e-42 169.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_4752283_1 1324957.K933_13893 6.635e-102 348.0 COG2843@1|root,arCOG07503@2157|Archaea 2157|Archaea M enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) - - - ko:K07282 - - - - ko00000 - - - PGA_cap DYD1_k127_4754093_3 289376.THEYE_A1803 1.763e-09 64.0 28U9C@1|root,2ZGEW@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4754093_1 861299.J421_3007 1.167e-21 95.0 2EQ8R@1|root,33HV0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4754093_2 1254432.SCE1572_00530 1.013e-09 68.0 COG0783@1|root,COG0783@2|Bacteria 2|Bacteria P Belongs to the Dps family - - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin DYD1_k127_4754093_4 240015.ACP_2023 2.965e-06 58.0 COG5424@1|root,COG5424@2|Bacteria,3Y718@57723|Acidobacteria,2JKMM@204432|Acidobacteriia 204432|Acidobacteriia H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2 DYD1_k127_4754093_0 671143.DAMO_0021 8.8e-55 199.0 COG3055@1|root,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria 2|Bacteria G Galactose oxidase, central domain - - - - - - - - - - - - Kelch_1,Kelch_4,Kelch_6 DYD1_k127_4781692_5 991905.SL003B_1041 1.816e-89 301.0 COG0559@1|root,COG0559@2|Bacteria,1MXHF@1224|Proteobacteria,2U4PU@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_4781692_3 991905.SL003B_1040 5.689e-112 375.0 COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,2TVFT@28211|Alphaproteobacteria,4BRDF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid transport system permease - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_4781692_9 671143.DAMO_2791 2.805e-30 122.0 COG1193@1|root,COG1193@2|Bacteria,2NRN7@2323|unclassified Bacteria 2|Bacteria L Smr domain mutS2 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr DYD1_k127_4781692_7 443144.GM21_3756 3.788e-41 157.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria 28221|Deltaproteobacteria M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 DYD1_k127_4781692_0 1123508.JH636439_gene1811 0.0 1311.0 COG0060@1|root,COG0060@2|Bacteria,2IWX2@203682|Planctomycetes 203682|Planctomycetes J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS DYD1_k127_4781692_10 1499967.BAYZ01000074_gene2192 3.601e-30 133.0 COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria 2|Bacteria M Lipid A biosynthesis - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD1_k127_4781692_8 333138.LQ50_20190 9.243e-31 131.0 COG0235@1|root,COG0235@2|Bacteria 2|Bacteria G Class ii aldolase araD - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II,UPF0066 DYD1_k127_4781692_1 76114.ebA5649 1.524e-291 900.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - - - - - - - - - - - UbiD DYD1_k127_4781692_6 868864.Dester_0028 8.475e-50 179.0 COG0347@1|root,COG0347@2|Bacteria,2G43N@200783|Aquificae 200783|Aquificae K Belongs to the P(II) protein family - - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II DYD1_k127_4781692_2 1121468.AUBR01000046_gene1917 2.024e-228 715.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42FXP@68295|Thermoanaerobacterales 186801|Clostridia E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N DYD1_k127_4781692_4 671143.DAMO_1683 8.332e-95 315.0 COG0004@1|root,COG0004@2|Bacteria,2NQS8@2323|unclassified Bacteria 2|Bacteria P Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - iHN637.CLJU_c42670,iYO844.BSU36510 Ammonium_transp DYD1_k127_47845_0 1131814.JAFO01000001_gene3485 4.01e-127 416.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria 28211|Alphaproteobacteria F COG0044 Dihydroorotase and related cyclic amidohydrolases - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 DYD1_k127_47845_1 1232410.KI421416_gene2600 9.905e-60 217.0 COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42NTB@68525|delta/epsilon subdivisions,2WKNX@28221|Deltaproteobacteria,43U98@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 DYD1_k127_4791024_4 697284.ERIC2_c35220 0.0002964 44.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,26QJC@186822|Paenibacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD DYD1_k127_4791024_3 443143.GM18_1380 6.004e-18 87.0 COG1476@1|root,COG1476@2|Bacteria,1NB6T@1224|Proteobacteria,42VWK@68525|delta/epsilon subdivisions,2WRMY@28221|Deltaproteobacteria,43VV4@69541|Desulfuromonadales 28221|Deltaproteobacteria K PFAM helix-turn-helix domain protein - - - - - - - - - - - - HTH_3 DYD1_k127_4791024_0 1125863.JAFN01000001_gene2287 7.357e-76 267.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria NU TIGRFAM type IV pilus assembly protein PilM pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 DYD1_k127_4791024_2 589865.DaAHT2_2312 2.103e-18 93.0 COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria,2MK8I@213118|Desulfobacterales 28221|Deltaproteobacteria NU PFAM Fimbrial assembly pilN - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN DYD1_k127_4791024_1 443143.GM18_1383 2.011e-35 144.0 COG3167@1|root,COG3167@2|Bacteria,1MZZ4@1224|Proteobacteria,43B6P@68525|delta/epsilon subdivisions,2X6K9@28221|Deltaproteobacteria,43TSB@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Pilus assembly protein, PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO DYD1_k127_481828_1 1382306.JNIM01000001_gene764 8.403e-60 218.0 COG2513@1|root,COG2513@2|Bacteria,2G6M0@200795|Chloroflexi 200795|Chloroflexi G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - - PEP_mutase DYD1_k127_481828_2 573064.Mefer_0041 4.116e-41 156.0 COG0066@1|root,arCOG02230@2157|Archaea,2XTXJ@28890|Euryarchaeota,23QQ2@183939|Methanococci 183939|Methanococci E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD1_k127_481828_0 224324.aq_940 3.344e-103 349.0 COG0065@1|root,COG0065@2|Bacteria,2G3S3@200783|Aquificae 200783|Aquificae H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase DYD1_k127_481828_3 443152.MDG893_15260 1.385e-30 134.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_4826938_2 42256.RradSPS_0139 2.609e-18 93.0 COG0500@1|root,COG2226@2|Bacteria,2HR9J@201174|Actinobacteria,4CRD1@84995|Rubrobacteria 84995|Rubrobacteria Q O-methyltransferase - - - - - - - - - - - - Methyltransf_25 DYD1_k127_4826938_1 1144310.PMI07_005585 9.844e-26 120.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_4826938_0 1382304.JNIL01000001_gene1506 1.352e-229 734.0 COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HC1W@91061|Bacilli,278QK@186823|Alicyclobacillaceae 91061|Bacilli C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_4829354_14 1391647.AVSV01000017_gene671 8.475e-07 53.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,36EAA@31979|Clostridiaceae 186801|Clostridia P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 DYD1_k127_4829354_12 203124.Tery_2073 6.029e-15 83.0 COG0662@1|root,COG0662@2|Bacteria,1GDUY@1117|Cyanobacteria 1117|Cyanobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_4829354_2 4533.OB08G10770.1 1.936e-71 254.0 COG1062@1|root,KOG0022@2759|Eukaryota,37MA7@33090|Viridiplantae,3G8YI@35493|Streptophyta,3KWS4@4447|Liliopsida,3I4HV@38820|Poales 35493|Streptophyta Q Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD1_k127_4829354_10 864073.HFRIS_000360 6.868e-19 93.0 COG1335@1|root,COG1335@2|Bacteria,1REG4@1224|Proteobacteria 1224|Proteobacteria Q PFAM Isochorismatase - - - - - - - - - - - - Isochorismatase DYD1_k127_4829354_1 314278.NB231_08798 3.049e-88 306.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,1X0B8@135613|Chromatiales 135613|Chromatiales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_2 DYD1_k127_4829354_0 1463855.JOHV01000001_gene1701 4.16e-112 376.0 COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria 201174|Actinobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske DYD1_k127_4829354_9 1144310.PMI07_005448 4.813e-20 100.0 COG0235@1|root,COG0235@2|Bacteria,1PV17@1224|Proteobacteria,2V6I8@28211|Alphaproteobacteria,4BJMN@82115|Rhizobiaceae 28211|Alphaproteobacteria G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II DYD1_k127_4829354_4 262316.MAP_1627 4.827e-47 183.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_4829354_7 44454.NF84_12460 1.955e-35 149.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_4829354_3 562970.Btus_0865 5.73e-48 183.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,27967@186823|Alicyclobacillaceae 91061|Bacilli M Male sterility protein rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind DYD1_k127_4829354_13 1123393.KB891326_gene242 1.82e-14 83.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,1KSV0@119069|Hydrogenophilales 119069|Hydrogenophilales O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD1_k127_4829354_11 1121406.JAEX01000003_gene1699 5.216e-15 85.0 COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2X2GQ@28221|Deltaproteobacteria,2MC2F@213115|Desulfovibrionales 28221|Deltaproteobacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 DYD1_k127_4829354_6 330214.NIDE4014 2.817e-36 152.0 2EUIU@1|root,33N0V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_4829354_8 247490.KSU1_B0681 3.043e-21 98.0 COG3437@1|root,COG3437@2|Bacteria,2IYS1@203682|Planctomycetes 203682|Planctomycetes T HD domain - - - - - - - - - - - - HD,Response_reg DYD1_k127_4829354_5 378806.STAUR_0763 7.304e-38 151.0 COG0500@1|root,COG2226@2|Bacteria,1RC36@1224|Proteobacteria,42UDA@68525|delta/epsilon subdivisions,2WQHW@28221|Deltaproteobacteria,2YV8X@29|Myxococcales 28221|Deltaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_31 DYD1_k127_4832192_10 1297617.JPJD01000050_gene1926 3.108e-76 273.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,2697G@186813|unclassified Clostridiales 186801|Clostridia H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ubiD - - ko:K16874 ko00365,ko01120,map00365,map01120 - R10213 RC03086 ko00000,ko00001 - - - UbiD DYD1_k127_4832192_1 1476876.JOJO01000036_gene4375 2.722e-215 692.0 COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria 201174|Actinobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_4832192_16 574375.BAGA_18060 1.524e-42 162.0 COG1917@1|root,COG1917@2|Bacteria,1V0SF@1239|Firmicutes,4HA58@91061|Bacilli,1ZEI3@1386|Bacillus 91061|Bacilli S Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO DYD1_k127_4832192_13 1123256.KB907943_gene455 4.816e-52 188.0 COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,1S69D@1236|Gammaproteobacteria,1XC2C@135614|Xanthomonadales 135614|Xanthomonadales S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 DYD1_k127_4832192_14 1298863.AUEP01000012_gene3767 3.058e-47 176.0 COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4DQ8W@85009|Propionibacteriales 201174|Actinobacteria F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran DYD1_k127_4832192_11 273075.Ta0575 7.151e-74 272.0 COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,241J0@183967|Thermoplasmata 183967|Thermoplasmata F aspartate carbamoyltransferase activity pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD1_k127_4832192_4 1232410.KI421413_gene595 1.04e-164 528.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales 28221|Deltaproteobacteria F Carbamoyl-phosphate synthase small chain, CPSase domain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase DYD1_k127_4832192_0 243231.GSU1276 0.0 1469.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS DYD1_k127_4832192_2 243231.GSU1326 2.943e-187 610.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales 28221|Deltaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge DYD1_k127_4832192_3 671143.DAMO_1503 8.65e-184 581.0 COG0436@1|root,COG0436@2|Bacteria,2NQG2@2323|unclassified Bacteria 2|Bacteria E Aminotransferase class I and II yfdZ GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 ko:K10206,ko:K14261 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - iEcSMS35_1347.EcSMS35_2531,iSBO_1134.SBO_2405 Aminotran_1_2 DYD1_k127_4832192_12 1121423.JONT01000014_gene1251 7.031e-67 246.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,2600D@186807|Peptococcaceae 186801|Clostridia E PFAM Homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 DYD1_k127_4832192_5 338963.Pcar_1514 1.273e-147 477.0 COG3635@1|root,COG3635@2|Bacteria,1R4TM@1224|Proteobacteria,42NCT@68525|delta/epsilon subdivisions,2WKEG@28221|Deltaproteobacteria,43SUK@69541|Desulfuromonadales 28221|Deltaproteobacteria G Proposed homoserine kinase apgM - 5.4.2.12 ko:K15635 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,PhosphMutase DYD1_k127_4832192_7 1201288.M900_A0332 4.551e-130 425.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2MSKZ@213481|Bdellovibrionales,2WKJ6@28221|Deltaproteobacteria 213481|Bdellovibrionales G TIGRFAM fructose-1,6-bisphosphatase, class II glpX - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX DYD1_k127_4832192_17 83406.HDN1F_14030 5.695e-34 140.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - 1.3.1.34,3.1.2.6 ko:K00219,ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Aminotran_5,Lactamase_B,Rhodanese DYD1_k127_4832192_18 797210.Halxa_3289 7.213e-32 134.0 COG3332@1|root,arCOG06429@2157|Archaea,2XU65@28890|Euryarchaeota,23UCP@183963|Halobacteria 183963|Halobacteria S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 DYD1_k127_4832192_8 326427.Cagg_0759 8.374e-121 395.0 COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,374WI@32061|Chloroflexia 32061|Chloroflexia S PFAM ATPase associated with various cellular activities, AAA_5 - - - - - - - - - - - - AAA_5 DYD1_k127_4832192_9 215803.DB30_5420 1.081e-95 330.0 COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,42QBK@68525|delta/epsilon subdivisions,2WITZ@28221|Deltaproteobacteria,2YW16@29|Myxococcales 28221|Deltaproteobacteria S VWA domain containing CoxE-like protein - - - ko:K07161 - - - - ko00000 - - - VWA_CoxE DYD1_k127_4832192_6 1283300.ATXB01000001_gene503 7.251e-140 460.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XDTH@135618|Methylococcales 135618|Methylococcales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 DYD1_k127_4832192_15 671143.DAMO_1375 1.936e-44 169.0 COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria 2|Bacteria S Bifunctional nuclease - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K03617,ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR DYD1_k127_4832192_19 767031.HMPREF9137_0132 1.654e-07 61.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia 976|Bacteroidetes S Tetratricopeptide repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8 DYD1_k127_4835094_5 322710.Avin_21320 3.836e-51 184.0 COG1053@1|root,COG1053@2|Bacteria 2|Bacteria C succinate dehydrogenase - - - - - - - - - - - - FAD_binding_2 DYD1_k127_4835094_4 706587.Desti_0199 4.937e-56 201.0 COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria 1224|Proteobacteria P Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide cynS - 4.2.1.104 ko:K01725 ko00910,map00910 - R03546,R10079 RC00952 ko00000,ko00001,ko01000 - - - Cyanate_lyase DYD1_k127_4835094_2 794903.OPIT5_02775 1.644e-99 331.0 COG1116@1|root,COG1116@2|Bacteria,46TGB@74201|Verrucomicrobia,3K9HD@414999|Opitutae 414999|Opitutae P ATPases associated with a variety of cellular activities - - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran DYD1_k127_4835094_3 1000565.METUNv1_01611 3.491e-89 303.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2VH12@28216|Betaproteobacteria,2KV7F@206389|Rhodocyclales 206389|Rhodocyclales P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - - - - - - - - - - BPD_transp_1 DYD1_k127_4835094_0 706587.Desti_0198 7.154e-192 609.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,42PHX@68525|delta/epsilon subdivisions,2WJY6@28221|Deltaproteobacteria 28221|Deltaproteobacteria P NMT1-like family - - - ko:K02051,ko:K15576 ko00910,ko02010,map00910,map02010 M00188,M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17 - - NMT1_2 DYD1_k127_4835094_1 443152.MDG893_15045 1.785e-130 424.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria 1224|Proteobacteria E ornithine cyclodeaminase - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_4844017_1 266265.Bxe_B2513 3.205e-58 212.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2VMW1@28216|Betaproteobacteria,1K1I4@119060|Burkholderiaceae 28216|Betaproteobacteria P 4,5-dihydroxyphthalate decarboxylase - - 4.1.1.55 ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000 - - - NMT1 DYD1_k127_4844017_2 388401.RB2150_08919 4.303e-35 141.0 COG0625@1|root,COG0625@2|Bacteria,1MWUG@1224|Proteobacteria,2TTZ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_3,GST_N,GST_N_3 DYD1_k127_4844017_0 485913.Krac_5038 1.366e-122 395.0 COG0702@1|root,COG0702@2|Bacteria 2|Bacteria GM epimerase - - - - - - - - - - - - NAD_binding_10 DYD1_k127_4951868_0 1041930.Mtc_1238 3.823e-75 260.0 COG1116@1|root,arCOG00193@2157|Archaea,2XT97@28890|Euryarchaeota,2N9FI@224756|Methanomicrobia 224756|Methanomicrobia E PFAM ABC transporter related ssuB - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_4951868_1 1173024.KI912153_gene32 4.634e-74 256.0 COG0600@1|root,COG0600@2|Bacteria,1G0UB@1117|Cyanobacteria 1117|Cyanobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_4951868_2 1144310.PMI07_004507 7.491e-22 108.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,4B98I@82115|Rhizobiaceae 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_496667_1 1120972.AUMH01000006_gene1898 4.72e-16 81.0 COG4638@1|root,COG4638@2|Bacteria 2|Bacteria P Rieske (2fe-2S) ligX - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_496667_0 1532558.JL39_06940 1.062e-21 108.0 COG1840@1|root,COG1840@2|Bacteria,1PGNJ@1224|Proteobacteria,2V7JA@28211|Alphaproteobacteria,4BDDZ@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 DYD1_k127_496667_2 298655.KI912266_gene3763 0.0001035 53.0 COG0715@1|root,COG0715@2|Bacteria,2HFUC@201174|Actinobacteria,4EX10@85013|Frankiales 201174|Actinobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_4970588_2 1095769.CAHF01000006_gene1703 1.226e-41 164.0 COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2VWNG@28216|Betaproteobacteria 28216|Betaproteobacteria S alpha beta - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_4970588_0 1463855.JOHV01000001_gene1701 7.27e-105 354.0 COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria 201174|Actinobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske DYD1_k127_4970588_3 1089545.KB913037_gene3657 2.432e-07 63.0 COG0715@1|root,COG0715@2|Bacteria,2I9KK@201174|Actinobacteria,4E19Q@85010|Pseudonocardiales 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_4970588_4 156978.CIMIT_11900 0.0006046 45.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,22QPQ@1653|Corynebacteriaceae 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - AAA_22,ANAPC5,GerE,TPR_12 DYD1_k127_4970588_1 1007104.SUS17_2452 7.781e-77 268.0 COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,2VEV5@28211|Alphaproteobacteria,2K7TR@204457|Sphingomonadales 204457|Sphingomonadales S K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - - - - - - - - - - Sortilin-Vps10 DYD1_k127_4971120_3 545264.KB898745_gene1347 9.256e-10 63.0 COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,1SPM8@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp DYD1_k127_4971120_1 93220.LV28_02775 3.638e-18 89.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria,1K74B@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_4971120_2 1123023.JIAI01000002_gene4973 5.277e-17 92.0 COG0715@1|root,COG0715@2|Bacteria,2IDBN@201174|Actinobacteria 201174|Actinobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_4971120_0 204669.Acid345_3931 1.152e-20 93.0 COG3033@1|root,COG3033@2|Bacteria,3Y3QK@57723|Acidobacteria 57723|Acidobacteria E Beta-eliminating lyase - - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase DYD1_k127_4977092_57 880072.Desac_1469 8.574e-11 66.0 COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,2MSHF@213462|Syntrophobacterales 28221|Deltaproteobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE DYD1_k127_4977092_19 335543.Sfum_1544 2.759e-78 270.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria,2MQF6@213462|Syntrophobacterales 28221|Deltaproteobacteria K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG DYD1_k127_4977092_27 1121459.AQXE01000006_gene265 6.472e-62 215.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2WNAH@28221|Deltaproteobacteria,2MB3K@213115|Desulfovibrionales 28221|Deltaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N DYD1_k127_4977092_12 795359.TOPB45_0167 6.328e-95 316.0 COG0081@1|root,COG0081@2|Bacteria,2GH9C@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA - - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 DYD1_k127_4977092_50 1122919.KB905578_gene3266 1.944e-28 121.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,26SAP@186822|Paenibacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 DYD1_k127_4977092_37 1123325.JHUV01000003_gene1576 5.345e-43 162.0 COG0222@1|root,COG0222@2|Bacteria,2G42K@200783|Aquificae 200783|Aquificae J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N DYD1_k127_4977092_1 316067.Geob_3632 0.0 1936.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,43T41@69541|Desulfuromonadales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 DYD1_k127_4977092_0 243231.GSU2862 0.0 2095.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria 28221|Deltaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 DYD1_k127_4977092_22 398767.Glov_1341 1.249e-65 225.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,43URA@69541|Desulfuromonadales 28221|Deltaproteobacteria J With S4 and S5 plays an important role in translational accuracy rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 DYD1_k127_4977092_26 706587.Desti_5258 4.368e-62 216.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MRJC@213462|Syntrophobacterales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 DYD1_k127_4977092_2 338966.Ppro_0677 0.0 1083.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,43SV3@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_4977092_36 644282.Deba_2939 1.513e-47 173.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2WP4K@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 DYD1_k127_4977092_20 909663.KI867150_gene1287 3.608e-72 249.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2MQDG@213462|Syntrophobacterales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 DYD1_k127_4977092_28 401526.TcarDRAFT_0999 1.416e-60 216.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4H24E@909932|Negativicutes 909932|Negativicutes J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 DYD1_k127_4977092_52 472759.Nhal_2387 2.85e-24 105.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1WZEK@135613|Chromatiales 135613|Chromatiales J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 DYD1_k127_4977092_9 309803.CTN_0996 3.555e-105 347.0 COG0090@1|root,COG0090@2|Bacteria,2GBXA@200918|Thermotogae 200918|Thermotogae J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C DYD1_k127_4977092_43 555779.Dthio_PD0323 1.885e-37 144.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2MBZW@213115|Desulfovibrionales 28221|Deltaproteobacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 DYD1_k127_4977092_42 1121413.JMKT01000010_gene963 6.974e-38 145.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2WQBH@28221|Deltaproteobacteria,2MBW5@213115|Desulfovibrionales 28221|Deltaproteobacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 DYD1_k127_4977092_11 1232410.KI421428_gene1236 2.579e-102 336.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,43T5Z@69541|Desulfuromonadales 28221|Deltaproteobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C DYD1_k127_4977092_29 316067.Geob_3618 2e-58 206.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria,43UND@69541|Desulfuromonadales 28221|Deltaproteobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 DYD1_k127_4977092_51 632335.Calkr_1751 5.497e-28 119.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,42GX3@68295|Thermoanaerobacterales 186801|Clostridia J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 DYD1_k127_4977092_25 316067.Geob_3615 8.475e-63 216.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2WNEK@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 DYD1_k127_4977092_46 264732.Moth_2449 3.686e-35 136.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,42GS5@68295|Thermoanaerobacterales 186801|Clostridia J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 DYD1_k127_4977092_18 632292.Calhy_1015 5.217e-79 269.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,42F2S@68295|Thermoanaerobacterales 186801|Clostridia J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C DYD1_k127_4977092_53 338963.Pcar_0714 1.587e-20 92.0 COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,43VH4@69541|Desulfuromonadales 28221|Deltaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 DYD1_k127_4977092_45 1379281.AVAG01000008_gene1373 1.357e-35 142.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MBXI@213115|Desulfovibrionales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 DYD1_k127_4977092_31 1128421.JAGA01000002_gene712 3.317e-54 195.0 COG0097@1|root,COG0097@2|Bacteria,2NPAS@2323|unclassified Bacteria 2|Bacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 DYD1_k127_4977092_44 644282.Deba_2922 2.472e-36 140.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2WQ8U@28221|Deltaproteobacteria 28221|Deltaproteobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p DYD1_k127_4977092_23 880072.Desac_1439 8.361e-65 225.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria,2MRKN@213462|Syntrophobacterales 28221|Deltaproteobacteria J Belongs to the universal ribosomal protein uS5 family rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C DYD1_k127_4977092_34 649639.Bcell_0141 1.041e-49 182.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,1ZFMY@1386|Bacillus 91061|Bacilli J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A DYD1_k127_4977092_3 335543.Sfum_1575 1.266e-201 635.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MQSV@213462|Syntrophobacterales 28221|Deltaproteobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY DYD1_k127_4977092_17 1125863.JAFN01000001_gene3315 1.735e-79 271.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid DYD1_k127_4977092_13 644282.Deba_2916 7.357e-94 314.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria 28221|Deltaproteobacteria J TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD1_k127_4977092_47 1162668.LFE_0905 3.888e-35 134.0 COG0361@1|root,COG0361@2|Bacteria,3J0QB@40117|Nitrospirae 40117|Nitrospirae J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a DYD1_k127_4977092_55 1303518.CCALI_02887 6.383e-12 68.0 COG0257@1|root,COG0257@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 DYD1_k127_4977092_35 56780.SYN_01598 6.794e-48 174.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2WPD5@28221|Deltaproteobacteria,2MRU2@213462|Syntrophobacterales 28221|Deltaproteobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 DYD1_k127_4977092_30 562970.Btus_0180 7.653e-55 196.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,279QJ@186823|Alicyclobacillaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 DYD1_k127_4977092_15 880072.Desac_1429 2.247e-89 300.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MRHQ@213462|Syntrophobacterales 28221|Deltaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 DYD1_k127_4977092_7 443143.GM18_0859 2.422e-131 427.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,43TN3@69541|Desulfuromonadales 28221|Deltaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L DYD1_k127_4977092_39 56780.SYN_01603 3.337e-40 153.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2MQIR@213462|Syntrophobacterales 28221|Deltaproteobacteria J PFAM ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 DYD1_k127_4977092_62 1041147.AUFB01000008_gene845 0.0001277 49.0 COG1917@1|root,COG1917@2|Bacteria,1QU6U@1224|Proteobacteria,2TY5T@28211|Alphaproteobacteria,4B9VK@82115|Rhizobiaceae 28211|Alphaproteobacteria S ChrR Cupin-like domain - - - - - - - - - - - - Cupin_7 DYD1_k127_4977092_48 1410617.JHXH01000008_gene2112 8.243e-35 139.0 COG1859@1|root,COG1859@2|Bacteria,1V49Y@1239|Firmicutes,24H56@186801|Clostridia,3WJ81@541000|Ruminococcaceae 186801|Clostridia J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase kptA - - ko:K07559 - - - - ko00000,ko01000,ko03016 - - - PTS_2-RNA DYD1_k127_4977092_40 614083.AWQR01000049_gene3200 2.211e-39 154.0 2B4TG@1|root,31XK1@2|Bacteria,1RIY8@1224|Proteobacteria,2VTMB@28216|Betaproteobacteria,4AF7U@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_4977092_5 404380.Gbem_2283 1.099e-174 564.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_1434 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d DYD1_k127_4977092_61 289377.HL41_01190 7.96e-05 53.0 COG3087@1|root,COG3087@2|Bacteria,2GHQP@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria D Sporulation related domain - - - - - - - - - - - - SPOR DYD1_k127_4977092_8 1125863.JAFN01000001_gene2405 1.005e-113 376.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2495 GATase,Glycos_trans_3N,Glycos_transf_3 DYD1_k127_4977092_21 518766.Rmar_1047 1.983e-66 235.0 COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1FJ8Y@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Indole-3-glycerol phosphate synthase trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS DYD1_k127_4977092_32 338966.Ppro_1292 3.847e-52 192.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales 28221|Deltaproteobacteria F Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI DYD1_k127_4977092_4 1232410.KI421415_gene3075 1.334e-176 562.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,43TSW@69541|Desulfuromonadales 28221|Deltaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696,ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_4977092_16 443144.GM21_0895 1.074e-84 289.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales 28221|Deltaproteobacteria F The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA DYD1_k127_4977092_14 909663.KI867150_gene2383 2.852e-90 314.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2MQBB@213462|Syntrophobacterales 28221|Deltaproteobacteria H Mur ligase, middle domain folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2475 Mur_ligase_C,Mur_ligase_M DYD1_k127_4977092_24 316067.Geob_1869 2.926e-63 244.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,43TYF@69541|Desulfuromonadales 28221|Deltaproteobacteria M Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iAF987.Gmet_2474 OstA,OstA_2,OstA_C DYD1_k127_4977092_41 378806.STAUR_4024 8.764e-39 148.0 COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales 28221|Deltaproteobacteria G Mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 DYD1_k127_4977092_6 671143.DAMO_2489 8.772e-172 557.0 COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria 2|Bacteria NU Type II secretion system (T2SS), protein E, N-terminal domain xpsE GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K02454,ko:K02652 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N DYD1_k127_4977092_10 933262.AXAM01000042_gene1810 6.029e-104 351.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2MIYV@213118|Desulfobacterales 28221|Deltaproteobacteria NU Type II secretion system (T2SS), protein F - - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF DYD1_k127_4977092_33 671143.DAMO_2487 6.052e-50 185.0 COG4968@1|root,COG4968@2|Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif lspG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG DYD1_k127_4977092_58 933262.AXAM01000042_gene1814 2.517e-08 64.0 COG4970@1|root,COG4970@2|Bacteria,1Q2B2@1224|Proteobacteria,43EWD@68525|delta/epsilon subdivisions,2X2AP@28221|Deltaproteobacteria,2MMAG@213118|Desulfobacterales 28221|Deltaproteobacteria NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl DYD1_k127_4977092_59 472759.Nhal_0443 4.686e-08 63.0 COG4967@1|root,COG4967@2|Bacteria,1N992@1224|Proteobacteria,1T2RT@1236|Gammaproteobacteria,1WZB5@135613|Chromatiales 135613|Chromatiales U Prokaryotic N-terminal methylation motif - - - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl DYD1_k127_4977092_54 177437.HRM2_30160 8.337e-15 84.0 COG4966@1|root,COG4966@2|Bacteria,1QEE6@1224|Proteobacteria,433H9@68525|delta/epsilon subdivisions,2WY1D@28221|Deltaproteobacteria,2MPCI@213118|Desulfobacterales 28221|Deltaproteobacteria NU pilus assembly protein PilW - - - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - - DYD1_k127_4977092_38 933262.AXAM01000042_gene1817 6.242e-42 175.0 COG1555@1|root,COG3156@1|root,COG1555@2|Bacteria,COG3156@2|Bacteria,1PQMW@1224|Proteobacteria,42T9B@68525|delta/epsilon subdivisions,2WPYT@28221|Deltaproteobacteria,2MKAN@213118|Desulfobacterales 28221|Deltaproteobacteria LU Type II secretion system (T2SS), protein K - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK DYD1_k127_4977092_56 671143.DAMO_2482 9.631e-12 78.0 COG3166@1|root,COG4972@1|root,COG3166@2|Bacteria,COG4972@2|Bacteria 2|Bacteria NU Pilus assembly protein pilN - - ko:K02461,ko:K02662,ko:K02663,ko:K12289 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15 - - PilM_2,PilN DYD1_k127_4977092_60 933262.AXAM01000042_gene1819 8.511e-06 56.0 2EUP8@1|root,33N52@2|Bacteria,1NH8T@1224|Proteobacteria,42XIN@68525|delta/epsilon subdivisions,2WSMX@28221|Deltaproteobacteria,2MM6P@213118|Desulfobacterales 28221|Deltaproteobacteria S Type II secretion system (T2SS), protein M subtype b - - - - - - - - - - - - T2SSM_b DYD1_k127_4977092_49 472759.Nhal_3648 4.517e-32 141.0 COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1WVZW@135613|Chromatiales 135613|Chromatiales NU Type II and III secretion system protein - - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N DYD1_k127_4978935_1 748247.AZKH_p0140 5.018e-132 430.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 DYD1_k127_4978935_2 56107.Cylst_2613 1.76e-90 310.0 COG1520@1|root,COG1520@2|Bacteria,1GDEQ@1117|Cyanobacteria 1117|Cyanobacteria S Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotrans DYD1_k127_4978935_3 1382306.JNIM01000001_gene1022 1.085e-62 219.0 COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi 200795|Chloroflexi C 2Fe-2S -binding domain protein - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_4978935_0 1382306.JNIM01000001_gene1023 1.962e-251 792.0 COG1529@1|root,COG1529@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrA - 1.3.7.9 ko:K04108 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_4981472_5 1254432.SCE1572_19815 2.12e-39 151.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2YZNI@29|Myxococcales 28221|Deltaproteobacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD,SDH_sah DYD1_k127_4981472_2 1254432.SCE1572_19820 9.04e-158 503.0 COG4864@1|root,COG4864@2|Bacteria,1MWP0@1224|Proteobacteria,42N9I@68525|delta/epsilon subdivisions,2WK7G@28221|Deltaproteobacteria 28221|Deltaproteobacteria S UPF0365 protein - - - - - - - - - - - - YdfA_immunity DYD1_k127_4981472_6 639282.DEFDS_1107 9.971e-38 149.0 COG2928@1|root,COG2928@2|Bacteria,2GFJU@200930|Deferribacteres 200930|Deferribacteres S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 DYD1_k127_4981472_7 935840.JAEQ01000004_gene646 8.977e-24 113.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_4981472_3 1121396.KB893058_gene2565 3.743e-74 258.0 COG0657@1|root,COG0657@2|Bacteria 2|Bacteria I acetylesterase activity - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3,Peptidase_S9 DYD1_k127_4981472_8 1232410.KI421428_gene1039 1.171e-14 79.0 COG1030@1|root,COG1030@2|Bacteria,1NKSJ@1224|Proteobacteria,432IQ@68525|delta/epsilon subdivisions,2WXUT@28221|Deltaproteobacteria 28221|Deltaproteobacteria O NfeD-like C-terminal, partner-binding - - - - - - - - - - - - NfeD DYD1_k127_4981472_4 215803.DB30_7152 1.607e-61 214.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2Z03M@29|Myxococcales 28221|Deltaproteobacteria S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 DYD1_k127_4981472_0 891968.Anamo_1586 2.462e-261 825.0 COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,3TA4P@508458|Synergistetes 508458|Synergistetes G PFAM glycosyl transferase family 20 - - 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K16055 ko00500,ko01100,map00500,map01100 - R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20,Trehalose_PPase DYD1_k127_4981472_1 460265.Mnod_1229 3.749e-163 523.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria,1JRBF@119045|Methylobacteriaceae 28211|Alphaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC DYD1_k127_4990608_0 1121937.AUHJ01000024_gene67 1.212e-109 359.0 COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,1RQYT@1236|Gammaproteobacteria,465WD@72275|Alteromonadaceae 1236|Gammaproteobacteria S Filamentation induced by cAMP protein fic - - - - - - - - - - - - Fic DYD1_k127_4990608_1 420324.KI912045_gene4108 2.857e-28 126.0 COG0265@1|root,COG0265@2|Bacteria,1MV63@1224|Proteobacteria,2TS54@28211|Alphaproteobacteria,1JRCY@119045|Methylobacteriaceae 28211|Alphaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 DYD1_k127_4991498_0 1294273.roselon_01189 9.497e-115 408.0 COG0438@1|root,COG4671@1|root,COG0438@2|Bacteria,COG4671@2|Bacteria,1RCDF@1224|Proteobacteria,2U44I@28211|Alphaproteobacteria 28211|Alphaproteobacteria M methyltransferase - - - - - - - - - - - - Glyco_tran_28_C,Glyco_trans_1_2 DYD1_k127_4991498_1 1033736.CAHK01000013_gene883 3.444e-69 267.0 COG0438@1|root,COG0438@2|Bacteria,2IGDP@201174|Actinobacteria 201174|Actinobacteria M Glycosyl Transferase - - - - - - - - - - - - Glyco_tran_28_C,Glyco_trans_1_2,Glyco_trans_1_4,Glycos_transf_2 DYD1_k127_4995443_1 1173263.Syn7502_03006 1.086e-79 274.0 COG0600@1|root,COG0600@2|Bacteria,1G1ZK@1117|Cyanobacteria,1GZMV@1129|Synechococcus 1117|Cyanobacteria P ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_4995443_0 671143.DAMO_1249 0.0 1064.0 COG1615@1|root,COG1615@2|Bacteria,2NQSF@2323|unclassified Bacteria 2|Bacteria S Uncharacterised protein family (UPF0182) - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K09118 - - - - ko00000 - - - UPF0182 DYD1_k127_4995443_2 909663.KI867150_gene989 1.873e-46 176.0 COG0398@1|root,COG0398@2|Bacteria,1QKZU@1224|Proteobacteria,42SRQ@68525|delta/epsilon subdivisions,2WP35@28221|Deltaproteobacteria,2MQG7@213462|Syntrophobacterales 28221|Deltaproteobacteria S PFAM SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc DYD1_k127_4995443_3 706587.Desti_4461 1.074e-19 91.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WKPK@28221|Deltaproteobacteria,2MRWV@213462|Syntrophobacterales 28221|Deltaproteobacteria V Bacitracin resistance protein BacA uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA DYD1_k127_4996056_0 1209984.BN978_00712 1.244e-152 496.0 COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria,237YQ@1762|Mycobacteriaceae 201174|Actinobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_4996056_3 309801.trd_1809 1.013e-41 165.0 COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia 189775|Thermomicrobia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_4996056_5 1033736.CAHK01000055_gene2916 6.944e-09 59.0 2B4KM@1|root,31XCU@2|Bacteria,2HCZQ@201174|Actinobacteria,4FB69@85019|Brevibacteriaceae 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_17 DYD1_k127_4996056_1 392499.Swit_0904 1.782e-133 441.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,2K6JZ@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the UbiD family - - 4.1.1.98 ko:K03182,ko:K16874 ko00130,ko00365,ko01100,ko01110,ko01120,map00130,map00365,map01100,map01110,map01120 M00117 R04985,R04986,R10213 RC00391,RC03086 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_4996056_4 1415756.JQMY01000003_gene3693 1.412e-10 63.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria 28211|Alphaproteobacteria P 4,5-dihydroxyphthalate decarboxylase - - 4.1.1.55 ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000 - - - NMT1 DYD1_k127_4996056_2 1306990.BARG01000030_gene3384 5.402e-83 289.0 COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria 201174|Actinobacteria Q Pfam Cupin - - 1.13.11.38,1.13.11.4 ko:K00450,ko:K11948 ko00350,ko00624,ko01100,ko01120,map00350,map00624,map01100,map01120 - R02656,R07657 RC00764,RC00937 ko00000,ko00001,ko01000 - - - Cupin_2 DYD1_k127_4996056_6 1304883.KI912532_gene1851 2.472e-07 59.0 COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,2VI0X@28216|Betaproteobacteria,2KUDW@206389|Rhodocyclales 206389|Rhodocyclales H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ pqqC - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4 DYD1_k127_4999713_0 765952.PUV_08150 3.212e-151 487.0 COG1233@1|root,COG1233@2|Bacteria 2|Bacteria Q all-trans-retinol 13,14-reductase activity pys - - - - - - - - - - - Amino_oxidase,NAD_binding_8 DYD1_k127_4999713_6 269798.CHU_0210 2.423e-08 58.0 COG2827@1|root,COG2827@2|Bacteria,4NUW1@976|Bacteroidetes,47SQN@768503|Cytophagia 976|Bacteroidetes L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD1_k127_4999713_4 1379698.RBG1_1C00001G0559 6.545e-31 128.0 COG1656@1|root,COG1656@2|Bacteria,2NPUJ@2323|unclassified Bacteria 2|Bacteria H Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C DYD1_k127_4999713_3 96561.Dole_0148 4.274e-69 253.0 COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales 28221|Deltaproteobacteria E PFAM transglutaminase domain protein - - - - - - - - - - - - Transglut_core DYD1_k127_4999713_1 1499967.BAYZ01000152_gene1432 1.023e-89 303.0 COG1131@1|root,COG1131@2|Bacteria,2NPDQ@2323|unclassified Bacteria 2|Bacteria V ATPases associated with a variety of cellular activities natA2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_4999713_2 379066.GAU_0825 7.922e-86 302.0 28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Putative ATP-binding cassette - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran_2 DYD1_k127_4999713_5 204669.Acid345_2395 1.255e-13 72.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - 2.7.11.1 ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_16,TPR_2,TPR_8 DYD1_k127_5001832_1 1121920.AUAU01000010_gene61 3.336e-84 288.0 COG0500@1|root,COG2226@2|Bacteria,3Y5HG@57723|Acidobacteria 57723|Acidobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_11 DYD1_k127_5001832_2 1267535.KB906767_gene5128 3.54e-33 131.0 2C19F@1|root,32ZRH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5001832_0 1267535.KB906767_gene4816 5.632e-112 368.0 COG3217@1|root,COG3217@2|Bacteria,3Y5TQ@57723|Acidobacteria,2JNG0@204432|Acidobacteriia 204432|Acidobacteriia S MOSC N-terminal beta barrel domain - - - ko:K07140 - - - - ko00000 - - - MOSC,MOSC_N DYD1_k127_5001832_4 933262.AXAM01000021_gene463 1.108e-07 54.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42P6W@68525|delta/epsilon subdivisions,2WIWM@28221|Deltaproteobacteria,2MPYD@213118|Desulfobacterales 28221|Deltaproteobacteria V N-6 DNA Methylase - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase DYD1_k127_5026728_0 1340493.JNIF01000004_gene801 1.616e-82 285.0 COG2006@1|root,COG2006@2|Bacteria 2|Bacteria U 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - DUF362 DYD1_k127_5026728_1 234267.Acid_1416 1.782e-30 131.0 COG1657@1|root,COG1657@2|Bacteria 2|Bacteria I PFAM Prenyltransferase squalene oxidase - - 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - SQHop_cyclase_C DYD1_k127_5044878_6 243365.CV_3366 1.057e-16 83.0 COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2VTX9@28216|Betaproteobacteria 28216|Betaproteobacteria C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane frdD - - ko:K00247 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Fumarate_red_D DYD1_k127_5044878_7 314282.PCNPT3_02020 8.643e-12 72.0 COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,1S419@1236|Gammaproteobacteria,2QI6P@267894|Psychromonadaceae 1236|Gammaproteobacteria C Fumarate reductase subunit C frdC GO:0000104,GO:0001539,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006996,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016635,GO:0022607,GO:0030030,GO:0030031,GO:0032991,GO:0040011,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048870,GO:0051179,GO:0051674,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0097588,GO:0098796,GO:0098797,GO:0098803 - ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - iYL1228.KPN_04551 Fumarate_red_C DYD1_k127_5044878_1 1122138.AQUZ01000004_gene889 1.674e-110 361.0 COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4DPU6@85009|Propionibacteriales 201174|Actinobacteria C Succinate dehydrogenase fumarate reductase sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_7,Fer4_8 DYD1_k127_5044878_0 443218.AS9A_2960 6.17e-242 760.0 COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,235KN@1762|Mycobacteriaceae 201174|Actinobacteria C Fumarate reductase flavoprotein C-term frdA GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 1.3.5.1,1.3.5.4,1.4.3.16 ko:K00239,ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1552 FAD_binding_2,Succ_DH_flav_C DYD1_k127_5044878_2 929712.KI912613_gene2630 9.128e-82 281.0 COG2048@1|root,COG2048@2|Bacteria,2H014@201174|Actinobacteria,4CPAS@84995|Rubrobacteria 84995|Rubrobacteria C Cysteine-rich domain - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - CCG DYD1_k127_5044878_3 1131269.AQVV01000001_gene1358 1.037e-65 237.0 COG0479@1|root,COG0479@2|Bacteria 2|Bacteria C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 DYD1_k127_5044878_4 324925.Ppha_2717 6.774e-23 101.0 COG1053@1|root,COG1053@2|Bacteria,1FDQ3@1090|Chlorobi 1090|Chlorobi C TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_5044878_5 330214.NIDE0310 4.719e-20 93.0 COG1053@1|root,COG1053@2|Bacteria,3J0ZM@40117|Nitrospirae 40117|Nitrospirae C Fumarate reductase flavoprotein C-term - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD1_k127_5046210_4 426117.M446_4900 9.256e-104 347.0 COG0535@1|root,COG0535@2|Bacteria,1NJZV@1224|Proteobacteria,2U4H8@28211|Alphaproteobacteria,1JSDQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Iron-sulfur cluster-binding domain - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM DYD1_k127_5046210_11 314230.DSM3645_22239 8.395e-20 101.0 COG0535@1|root,COG0535@2|Bacteria,2J0M5@203682|Planctomycetes 203682|Planctomycetes S 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_12,Radical_SAM DYD1_k127_5046210_9 316067.Geob_2472 7.814e-31 129.0 COG0500@1|root,COG2226@2|Bacteria,1PEBD@1224|Proteobacteria,42T7H@68525|delta/epsilon subdivisions,2WPN7@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 DYD1_k127_5046210_7 194867.ALBQ01000017_gene2388 1.948e-60 216.0 COG0500@1|root,COG2226@2|Bacteria,1PVPS@1224|Proteobacteria,2TREE@28211|Alphaproteobacteria,2JZZE@204457|Sphingomonadales 204457|Sphingomonadales Q ubiquinone menaquinone biosynthesis - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 DYD1_k127_5046210_5 671143.DAMO_0610 4.688e-77 263.0 COG0494@1|root,COG0494@2|Bacteria,2NPTC@2323|unclassified Bacteria 2|Bacteria L NUDIX domain nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX DYD1_k127_5046210_12 671143.DAMO_0483 7.48e-10 62.0 COG3222@1|root,COG3222@2|Bacteria,2NRHT@2323|unclassified Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 DYD1_k127_5046210_10 1122179.KB890497_gene2776 1.053e-22 112.0 COG3202@1|root,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1IPY8@117747|Sphingobacteriia 976|Bacteroidetes C lyase activity - - - ko:K03301 - - - - ko00000 2.A.12 - - TLC,cNMP_binding DYD1_k127_5046210_6 1122128.AUEE01000016_gene2072 7.015e-75 266.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli,4GY72@90964|Staphylococcaceae 91061|Bacilli C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim DYD1_k127_5046210_13 648757.Rvan_2328 1.01e-07 54.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,3N6AJ@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim DYD1_k127_5046210_8 880072.Desac_2180 2.702e-37 144.0 COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2WRUT@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM S23 ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_5046210_0 671143.DAMO_0621 0.0 1406.0 COG1452@1|root,COG1452@2|Bacteria 2|Bacteria M lipopolysaccharide transport - - - ko:K22110 - - - - ko00000,ko02000 1.B.35.1,1.B.35.2 - - Glyco_hydro_63 DYD1_k127_5046210_1 1496688.ER33_11555 1.69e-249 788.0 COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium 1117|Cyanobacteria G Amylo-alpha-1,6-glucosidase - - - - - - - - - - - - GDE_C,GDE_N DYD1_k127_5046210_2 211165.AJLN01000061_gene3947 8.61e-151 486.0 COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1JK2A@1189|Stigonemataceae 1117|Cyanobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_5046210_3 861299.J421_1872 1.832e-150 480.0 COG2303@1|root,COG2303@2|Bacteria 2|Bacteria E choline dehydrogenase activity - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N DYD1_k127_5056567_2 1125863.JAFN01000001_gene3041 1.437e-19 104.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - DUF3794,FecR,LysM,Peptidase_M15_2,Peptidase_M74 DYD1_k127_5056567_0 439235.Dalk_0769 2.589e-172 552.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2MIN7@213118|Desulfobacterales 28221|Deltaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g DYD1_k127_5056567_1 1097668.BYI23_C003130 4.586e-132 440.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2WBWM@28216|Betaproteobacteria,1K6TM@119060|Burkholderiaceae 28216|Betaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - - - - - - - - - - UbiD DYD1_k127_5056567_3 882378.RBRH_00145 8.131e-16 87.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,1K0MR@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator cbl - - ko:K13634,ko:K13635 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD1_k127_5060502_1 118161.KB235922_gene402 5.422e-52 188.0 COG0500@1|root,COG2226@2|Bacteria,1G29G@1117|Cyanobacteria,3VHN7@52604|Pleurocapsales 1117|Cyanobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 DYD1_k127_5060502_2 479435.Kfla_5216 1.842e-33 137.0 COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DMYC@85009|Propionibacteriales 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigH GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_5060502_5 247490.KSU1_C0565 2.389e-07 62.0 COG5662@1|root,COG5662@2|Bacteria,2J40M@203682|Planctomycetes 203682|Planctomycetes K AntiSigma factor - - - - - - - - - - - - - DYD1_k127_5060502_0 880073.Calab_1379 6.965e-130 423.0 COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria 2|Bacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD1_k127_5060502_3 330214.NIDE4088 1.005e-25 113.0 COG0319@1|root,COG0319@2|Bacteria,3J0US@40117|Nitrospirae 40117|Nitrospirae J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 DYD1_k127_5060502_4 485913.Krac_1496 5.96e-14 72.0 COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_4 DYD1_k127_5062871_6 204773.HEAR0417 3.521e-74 252.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4729F@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctA family tctA4 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD1_k127_5062871_10 375286.mma_0471 4.717e-45 171.0 29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VT23@28216|Betaproteobacteria,474HM@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctB family tctB4 - - - - - - - - - - - TctB DYD1_k127_5062871_0 1502852.FG94_05179 4.998e-157 501.0 COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,472N8@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor tctC4 - - - - - - - - - - - TctC DYD1_k127_5062871_4 247633.GP2143_12991 4.889e-82 287.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1S0H1@1236|Gammaproteobacteria,1JBTT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Zn-dependent alcohol dehydrogenases - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_5062871_8 1500897.JQNA01000002_gene4715 1.437e-56 205.0 COG0695@1|root,COG0695@2|Bacteria,1RC6T@1224|Proteobacteria,2VQW9@28216|Betaproteobacteria,1K5H4@119060|Burkholderiaceae 28216|Betaproteobacteria O DinB superfamily - - - - - - - - - - - - DinB_2,Glutaredoxin DYD1_k127_5062871_3 243231.GSU1010 3.777e-82 290.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,43U1B@69541|Desulfuromonadales 28221|Deltaproteobacteria M Lytic transglycosylase, SLT, LysM and LysM domain-containing mltD2 - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD1_k127_5062871_14 694431.DESACE_07530 1.07e-22 111.0 COG2223@1|root,COG2223@2|Bacteria,1MXAA@1224|Proteobacteria,43BPJ@68525|delta/epsilon subdivisions,2WK2H@28221|Deltaproteobacteria,2M6U1@213113|Desulfurellales 28221|Deltaproteobacteria P Major Facilitator Superfamily - - - ko:K08223 - - - - ko00000,ko02000 2.A.1.35 - - MFS_1 DYD1_k127_5062871_2 443152.MDG893_15040 3.817e-97 330.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria 1224|Proteobacteria E ornithine cyclodeaminase - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_5062871_9 298654.FraEuI1c_2811 8.537e-48 185.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria 201174|Actinobacteria S Pfam Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_5062871_7 365046.Rta_20260 1.349e-73 255.0 COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2VMGM@28216|Betaproteobacteria,4ABY0@80864|Comamonadaceae 28216|Betaproteobacteria ET SMART Extracellular solute-binding protein, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD1_k127_5062871_1 404589.Anae109_1579 1.09e-119 389.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales 28221|Deltaproteobacteria S Rhomboid family - - - - - - - - - - - - Rhomboid DYD1_k127_5062871_11 240292.Ava_2299 2.021e-34 144.0 COG2304@1|root,COG2304@2|Bacteria,1G7H7@1117|Cyanobacteria,1HM3S@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function (DUF1194) - - - - - - - - - - - - DUF1194,VPEP DYD1_k127_5062871_17 284031.JNXD01000025_gene367 5.037e-12 70.0 COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_5062871_15 1380356.JNIK01000003_gene1302 2.456e-17 94.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU6Y@85013|Frankiales 201174|Actinobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5062871_5 264198.Reut_B5778 2.602e-74 264.0 COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1K2TY@119060|Burkholderiaceae 28216|Betaproteobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - - DYD1_k127_5062871_19 272568.GDI1503 8.087e-05 49.0 COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1MXER@1224|Proteobacteria,2TSPK@28211|Alphaproteobacteria,2JQPY@204441|Rhodospirillales 204441|Rhodospirillales CF 4Fe-4S dicluster domain - - 1.3.1.1 ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh,Fer4_21 DYD1_k127_5062871_18 868864.Dester_1423 4.037e-07 55.0 COG1143@1|root,COG1143@2|Bacteria,2G59W@200783|Aquificae 200783|Aquificae C 4Fe-4S binding domain - - - - - - - - - - - - Fer4 DYD1_k127_5062871_13 911239.CF149_12813 2.888e-27 123.0 COG2267@1|root,COG2267@2|Bacteria,1MZG8@1224|Proteobacteria,1RQYM@1236|Gammaproteobacteria 1236|Gammaproteobacteria I hydrolases or acyltransferases (alpha beta hydrolase superfamily) mhpC - 3.7.1.17 ko:K16050 ko00984,ko01100,ko01120,ko01220,map00984,map01100,map01120,map01220 - R09883 RC02018,RC02740 ko00000,ko00001,ko01000 - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_5062871_12 273075.Ta1053 8.863e-30 126.0 COG1335@1|root,arCOG01943@2157|Archaea,2Y1IW@28890|Euryarchaeota,2427T@183967|Thermoplasmata 183967|Thermoplasmata Q Isochorismatase family - - - - - - - - - - - - Isochorismatase DYD1_k127_5068085_2 1298867.AUES01000010_gene5864 5.104e-24 103.0 COG1149@1|root,COG1149@2|Bacteria,1QTYV@1224|Proteobacteria,2TTH3@28211|Alphaproteobacteria,3JV8K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C TIGRFAM CitB domain protein tcuB - - ko:K13795 - - - - ko00000 - - - - DYD1_k127_5068085_0 2074.JNYD01000014_gene7087 1.452e-81 285.0 COG2141@1|root,COG2141@2|Bacteria,2H2UE@201174|Actinobacteria 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_5068085_3 1353531.AZNX01000001_gene1413 2.928e-17 86.0 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria,4BENB@82115|Rhizobiaceae 28211|Alphaproteobacteria S Cupin 2 conserved barrel domain protein MA20_13155 - - - - - - - - - - - Cupin_2 DYD1_k127_5068085_7 1120983.KB894570_gene1495 2.965e-06 58.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2UK4T@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K08234 - - - - ko00000 - - - Glyoxalase,Glyoxalase_4 DYD1_k127_5068085_4 926560.KE387023_gene2124 1.845e-09 69.0 COG0715@1|root,COG0715@2|Bacteria,1WJPE@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_5068085_5 631454.N177_2294 1.002e-07 63.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - - - - - - - - - - NMT1 DYD1_k127_5068085_1 1120936.KB907221_gene2112 6.379e-77 269.0 COG2159@1|root,COG2159@2|Bacteria,2GN9D@201174|Actinobacteria 201174|Actinobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_5068085_8 1380356.JNIK01000017_gene2825 9.331e-05 53.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase,Glyoxalase_4 DYD1_k127_5068085_6 227882.SAV_5962 1.254e-07 63.0 COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_5069878_3 234267.Acid_2016 7.465e-19 92.0 COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria 57723|Acidobacteria L PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1,RVT_N DYD1_k127_5069878_1 378806.STAUR_1477 3.768e-25 109.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YWK2@29|Myxococcales 28221|Deltaproteobacteria L Reverse transcriptase (RNA-dependent DNA polymerase) - - - - - - - - - - - - RVT_1 DYD1_k127_5069878_4 224911.27350214 2.654e-11 68.0 2FDBU@1|root,345DN@2|Bacteria,1NPWB@1224|Proteobacteria,2UT7E@28211|Alphaproteobacteria,3K4EQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Ribbon-helix-helix protein, copG family - - - - - - - - - - - - RHH_1 DYD1_k127_5069878_0 314278.NB231_11419 4.282e-209 670.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,1RP3U@1236|Gammaproteobacteria,1WZUN@135613|Chromatiales 135613|Chromatiales L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom DYD1_k127_5069878_2 331678.Cphamn1_1507 6.876e-20 90.0 COG1609@1|root,COG1609@2|Bacteria 2|Bacteria K purine nucleotide biosynthetic process - - 5.3.1.12 ko:K01812,ko:K02529,ko:K16210 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 2.A.2.5 - - DDE_Tnp_ISAZ013,Peripla_BP_3 DYD1_k127_5081100_11 246197.MXAN_0918 2.12e-52 195.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,431I4@68525|delta/epsilon subdivisions,2WW88@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_5081100_7 479434.Sthe_2813 6.74e-71 249.0 COG1319@1|root,COG1319@2|Bacteria,2G7KW@200795|Chloroflexi,27Z00@189775|Thermomicrobia 189775|Thermomicrobia C CO dehydrogenase flavoprotein domain protein - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_5081100_8 309801.trd_A0776 1.092e-64 226.0 COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi 2|Bacteria C 2Fe-2S -binding domain protein coxS - 1.2.5.3,1.3.99.16,1.5.99.4 ko:K03518,ko:K07302,ko:K19819 ko00760,ko01120,map00760,map01120 M00810 R02860,R07946,R11168 RC00589,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Fer2,Fer2_2 DYD1_k127_5081100_0 1408254.T458_21695 4.507e-187 616.0 COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HC1W@91061|Bacilli,26S7Z@186822|Paenibacillaceae 91061|Bacilli C Xanthine dehydrogenase - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_5081100_15 395495.Lcho_3339 1.132e-05 51.0 COG1942@1|root,COG1942@2|Bacteria,1N7K1@1224|Proteobacteria,2WAKW@28216|Betaproteobacteria,1KMRV@119065|unclassified Burkholderiales 28216|Betaproteobacteria G Tautomerase enzyme - - 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase DYD1_k127_5081100_2 1089553.Tph_c23930 7.153e-124 411.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42HS5@68295|Thermoanaerobacterales 186801|Clostridia H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ubiD - - ko:K16874 ko00365,ko01120,map00365,map01120 - R10213 RC03086 ko00000,ko00001 - - - UbiD DYD1_k127_5081100_4 1231391.AMZF01000121_gene3464 8.495e-109 360.0 COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2VNRV@28216|Betaproteobacteria 28216|Betaproteobacteria I esterase - - 3.5.1.9 ko:K01432 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3,COesterase DYD1_k127_5081100_1 502025.Hoch_6864 6.395e-159 520.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales 28221|Deltaproteobacteria E PFAM peptidase M3A and M3B thimet oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N DYD1_k127_5081100_5 1499967.BAYZ01000028_gene1316 4.95e-94 323.0 COG1058@1|root,COG1058@2|Bacteria,2NP0G@2323|unclassified Bacteria 2|Bacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth DYD1_k127_5081100_6 289376.THEYE_A1499 9.233e-74 259.0 COG0496@1|root,COG0496@2|Bacteria,3J0IG@40117|Nitrospirae 40117|Nitrospirae S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD1_k127_5081100_12 472759.Nhal_2693 6.937e-36 140.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1WYI6@135613|Chromatiales 135613|Chromatiales J Belongs to the HSP15 family - - - ko:K04762 - - - - ko00000,ko03110 - - - S4 DYD1_k127_5081100_10 857087.Metme_2403 1.051e-53 204.0 COG0642@1|root,COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XEIX@135618|Methylococcales 135618|Methylococcales T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - - - - - - - - - - CHASE8,HAMP,HATPase_c,HisKA,PAS_9,Response_reg DYD1_k127_5081100_13 886293.Sinac_5019 7.49e-16 84.0 COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes 203682|Planctomycetes T Universal stress protein - - - - - - - - - - - - Usp DYD1_k127_5081100_14 1121448.DGI_2855 2.833e-11 71.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,2MC4D@213115|Desulfovibrionales 28221|Deltaproteobacteria T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR DYD1_k127_5081100_9 690850.Desaf_1348 2.283e-64 232.0 2DM0H@1|root,316A1@2|Bacteria,1N0X9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_5081100_3 665571.STHERM_c14270 8.115e-118 387.0 COG0180@1|root,COG0180@2|Bacteria,2J68U@203691|Spirochaetes 203691|Spirochaetes J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b DYD1_k127_5092659_4 234267.Acid_7201 3.3e-81 281.0 COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria 57723|Acidobacteria S Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_5092659_5 404380.Gbem_1310 4.972e-49 179.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria,43SJ9@69541|Desulfuromonadales 28221|Deltaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase DYD1_k127_5092659_2 316067.Geob_2894 1.748e-173 554.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,43TS7@69541|Desulfuromonadales 28221|Deltaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 DYD1_k127_5092659_6 1117108.PAALTS15_03942 3.718e-24 104.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,26Z31@186822|Paenibacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS DYD1_k127_5092659_3 1121428.DESHY_70012___1 6.865e-88 297.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,260V1@186807|Peptococcaceae 186801|Clostridia F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 DYD1_k127_5092659_0 330214.NIDE1392 3.957e-288 902.0 COG0046@1|root,COG0046@2|Bacteria,3J0TJ@40117|Nitrospirae 40117|Nitrospirae F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,GATase_5 DYD1_k127_5092659_1 330214.NIDE1393 5.378e-191 605.0 COG0034@1|root,COG0034@2|Bacteria,3J0C5@40117|Nitrospirae 40117|Nitrospirae F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_7,Pribosyltran DYD1_k127_5094758_1 1134413.ANNK01000092_gene185 1.375e-43 166.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZAXG@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family yngF - - - - - - - - - - - ECH_1 DYD1_k127_5094758_4 1122915.AUGY01000020_gene6479 3.712e-24 115.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_5094758_5 189753.AXAS01000041_gene2534 7.89e-20 94.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5094758_3 1123504.JQKD01000004_gene5011 4.393e-27 115.0 COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,2VV15@28216|Betaproteobacteria,4AJFM@80864|Comamonadaceae 28216|Betaproteobacteria S Rubredoxin-like zinc ribbon domain (DUF35_N) - - - ko:K07068 - - - - ko00000 - - - DUF35_N,OB_aCoA_assoc DYD1_k127_5094758_0 1437448.AZRT01000129_gene253 1.452e-84 296.0 COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acetyl-coa acetyltransferase - - - - - - - - - - - - - DYD1_k127_5094758_2 1382306.JNIM01000001_gene261 6.128e-41 165.0 COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi 200795|Chloroflexi C PFAM acyl-CoA dehydrogenase domain protein - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_5100176_1 697282.Mettu_0560 3.832e-27 119.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1XFJD@135618|Methylococcales 135618|Methylococcales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - DPBB_1 DYD1_k127_5100176_0 1283300.ATXB01000001_gene1244 1.252e-97 333.0 COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,1S884@1236|Gammaproteobacteria,1XGAP@135618|Methylococcales 135618|Methylococcales NU Protein of unknown function (DUF1207) - - - - - - - - - - - - DUF1207 DYD1_k127_5100176_2 86106.I862_00660 3.116e-17 93.0 COG2823@1|root,COG2823@2|Bacteria 2|Bacteria S hyperosmotic response - - - ko:K04065 - - - - ko00000 - - - BON DYD1_k127_5101534_0 1449063.JMLS01000009_gene2253 1.158e-45 169.0 COG0251@1|root,COG0251@2|Bacteria,1V6G4@1239|Firmicutes,4HMTM@91061|Bacilli,26XE2@186822|Paenibacillaceae 91061|Bacilli J YjgF/chorismate_mutase-like, putative endoribonuclease - - - - - - - - - - - - YjgF_endoribonc DYD1_k127_5101534_1 1120936.KB907221_gene2112 2.351e-11 68.0 COG2159@1|root,COG2159@2|Bacteria,2GN9D@201174|Actinobacteria 201174|Actinobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_5107865_5 1499967.BAYZ01000034_gene1071 4.329e-21 96.0 2E46N@1|root,32Z2M@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5107865_3 671143.DAMO_2378 8.638e-41 153.0 COG2151@1|root,COG2151@2|Bacteria,2NPUI@2323|unclassified Bacteria 2|Bacteria S Pfam:DUF59 paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P DYD1_k127_5107865_4 1267534.KB906760_gene1554 1.171e-26 113.0 2DD3Z@1|root,2ZGDH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5107865_7 1198232.CYCME_1599 2.735e-05 50.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria,461DH@72273|Thiotrichales 72273|Thiotrichales S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc DYD1_k127_5107865_8 999549.KI421513_gene923 0.0009065 44.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,2808Q@191028|Leisingera 28211|Alphaproteobacteria CO Thioredoxin-like tlpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - AhpC-TSA,Redoxin DYD1_k127_5107865_0 502025.Hoch_4238 6.909e-148 488.0 COG1109@1|root,COG1482@1|root,COG1109@2|Bacteria,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,42QR1@68525|delta/epsilon subdivisions,2WU24@28221|Deltaproteobacteria,2YUXK@29|Myxococcales 28221|Deltaproteobacteria G Phosphomannose isomerase type I - - 5.3.1.8,5.4.2.8 ko:K01809,ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818,R01819 RC00376,RC00408 ko00000,ko00001,ko00002,ko01000 - - - PMI_typeI DYD1_k127_5107865_2 314345.SPV1_11936 9.464e-52 187.0 COG5156@1|root,COG5156@2|Bacteria,1N53Q@1224|Proteobacteria 1224|Proteobacteria DO anaphase-promoting complex-dependent catabolic process - - - - - - - - - - - - F5_F8_type_C DYD1_k127_5107865_1 404589.Anae109_1288 3.687e-74 252.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2Z08H@29|Myxococcales 28221|Deltaproteobacteria C Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 DYD1_k127_5107865_6 111780.Sta7437_1437 1.055e-08 57.0 COG0719@1|root,COG0719@2|Bacteria,1G0TH@1117|Cyanobacteria,3VI6W@52604|Pleurocapsales 1117|Cyanobacteria O FeS assembly protein SufB sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 DYD1_k127_5143958_1 306281.AJLK01000105_gene3517 7.899e-54 192.0 COG3791@1|root,COG3791@2|Bacteria,1GAQM@1117|Cyanobacteria,1JKVU@1189|Stigonemataceae 1117|Cyanobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD1_k127_5143958_4 1509405.GV67_12630 2.656e-07 58.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5143958_2 443152.MDG893_15260 2.509e-15 86.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_5143958_3 391623.TERMP_00457 2.553e-09 63.0 COG1656@1|root,COG2442@1|root,arCOG04290@2157|Archaea,arCOG07520@2157|Archaea,2Y1HG@28890|Euryarchaeota,244W7@183968|Thermococci 183968|Thermococci S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 DYD1_k127_5143958_0 627192.SLG_25610 7.686e-88 296.0 COG4341@1|root,COG4341@2|Bacteria,1RAX5@1224|Proteobacteria,2U5RV@28211|Alphaproteobacteria,2KAD4@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD1_k127_5151862_2 1122611.KB903953_gene5730 4.207e-06 49.0 COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4EJKT@85012|Streptosporangiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_5151862_1 1306990.BARG01000030_gene3384 1.781e-96 326.0 COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria 201174|Actinobacteria Q Pfam Cupin - - 1.13.11.38,1.13.11.4 ko:K00450,ko:K11948 ko00350,ko00624,ko01100,ko01120,map00350,map00624,map01100,map01120 - R02656,R07657 RC00764,RC00937 ko00000,ko00001,ko01000 - - - Cupin_2 DYD1_k127_5151862_3 675635.Psed_0738 4.848e-06 57.0 COG5424@1|root,COG5424@2|Bacteria,2I9SS@201174|Actinobacteria,4E9QU@85010|Pseudonocardiales 201174|Actinobacteria H TENA/THI-4/PQQC family pqqC - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4 DYD1_k127_5151862_0 1476876.JOJO01000036_gene4375 1.416e-211 681.0 COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria 201174|Actinobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_5153758_1 246194.CHY_1716 9.318e-28 119.0 COG1669@1|root,COG2250@1|root,COG1669@2|Bacteria,COG2250@2|Bacteria,1UJ0P@1239|Firmicutes,25ETF@186801|Clostridia,42JG1@68295|Thermoanaerobacterales 186801|Clostridia S Nucleotidyltransferase domain - - - ko:K07076 - - - - ko00000 - - - NTP_transf_2 DYD1_k127_5153758_3 246194.CHY_1716 1.706e-14 79.0 COG1669@1|root,COG2250@1|root,COG1669@2|Bacteria,COG2250@2|Bacteria,1UJ0P@1239|Firmicutes,25ETF@186801|Clostridia,42JG1@68295|Thermoanaerobacterales 186801|Clostridia S Nucleotidyltransferase domain - - - ko:K07076 - - - - ko00000 - - - NTP_transf_2 DYD1_k127_5153758_0 338966.Ppro_0982 4.161e-87 295.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales 28221|Deltaproteobacteria M Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 DYD1_k127_5153758_5 1286631.X805_06780 0.0001357 50.0 COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VV1S@28216|Betaproteobacteria 28216|Betaproteobacteria NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl DYD1_k127_5153758_4 933262.AXAM01000061_gene1670 2.278e-06 57.0 COG4967@1|root,COG4967@2|Bacteria,1NI49@1224|Proteobacteria,42X6W@68525|delta/epsilon subdivisions,2WSY4@28221|Deltaproteobacteria,2MMCT@213118|Desulfobacterales 28221|Deltaproteobacteria NU Prokaryotic N-terminal methylation motif - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl DYD1_k127_5153758_2 56780.SYN_01757 3.388e-15 85.0 COG4966@1|root,COG4966@2|Bacteria,1Q8WE@1224|Proteobacteria,439J3@68525|delta/epsilon subdivisions,2X4VK@28221|Deltaproteobacteria,2MSHQ@213462|Syntrophobacterales 28221|Deltaproteobacteria NU Pfam:N_methyl_2 - - - - - - - - - - - - N_methyl DYD1_k127_5200460_6 1415754.JQMK01000013_gene404 0.0002068 51.0 COG2931@1|root,COG2931@2|Bacteria,1N32T@1224|Proteobacteria,1S9CA@1236|Gammaproteobacteria,4681W@72275|Alteromonadaceae 1236|Gammaproteobacteria Q Protein of unknown function (DUF642) - - - - - - - - - - - - DUF642,VPEP DYD1_k127_5200460_3 1120973.AQXL01000130_gene1244 3.696e-13 79.0 COG5424@1|root,COG5424@2|Bacteria,1VNTM@1239|Firmicutes,4HSNP@91061|Bacilli 91061|Bacilli H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2 DYD1_k127_5200460_2 675635.Psed_2624 2.326e-63 226.0 COG1878@1|root,COG1878@2|Bacteria,2I66K@201174|Actinobacteria,4E76K@85010|Pseudonocardiales 201174|Actinobacteria S Putative cyclase - - - - - - - - - - - - Cyclase DYD1_k127_5200460_1 266265.Bxe_B2813 1.308e-69 247.0 COG0329@1|root,COG0329@2|Bacteria,1NQJ0@1224|Proteobacteria 1224|Proteobacteria EM Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD1_k127_5200460_0 1128421.JAGA01000002_gene1959 2.583e-111 368.0 COG0446@1|root,COG0446@2|Bacteria,2NPPU@2323|unclassified Bacteria 2|Bacteria S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_5254493_3 1192034.CAP_0604 5.013e-54 192.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YU4Q@29|Myxococcales 28221|Deltaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa DYD1_k127_5254493_4 1123326.JFBL01000011_gene186 6.07e-44 164.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2YQ7X@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria C NADH-quinone oxidoreductase nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx DYD1_k127_5254493_0 156889.Mmc1_3630 8.062e-166 531.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB DYD1_k127_5254493_1 1191523.MROS_2032 3.795e-127 425.0 COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria 2|Bacteria C formate dehydrogenase (NAD+) activity nuoG - 1.12.1.2,1.6.5.3 ko:K00336,ko:K18006 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD1_k127_5254493_2 1131269.AQVV01000018_gene1931 2.355e-107 359.0 COG1005@1|root,COG1005@2|Bacteria 2|Bacteria C quinone binding nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD1_k127_5254493_6 671143.DAMO_2694 2.474e-24 110.0 COG0839@1|root,COG0839@2|Bacteria,2NPUC@2323|unclassified Bacteria 2|Bacteria C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD1_k127_5254493_5 671143.DAMO_2693 4.202e-31 124.0 COG0713@1|root,COG0713@2|Bacteria,2NPU2@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340,ko:K05576 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD1_k127_5254493_7 1300345.LF41_2854 4.961e-12 69.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1X2Y0@135614|Xanthomonadales 135614|Xanthomonadales CP NADH ubiquinone oxidoreductase subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N DYD1_k127_5255556_3 698757.Pogu_1518 1.357e-17 90.0 COG0235@1|root,arCOG04226@2157|Archaea,2XQS6@28889|Crenarchaeota 28889|Crenarchaeota G PFAM class II aldolase adducin family protein - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II DYD1_k127_5255556_1 477974.Daud_0648 1.632e-50 198.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,260GP@186807|Peptococcaceae 186801|Clostridia J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B DYD1_k127_5255556_2 666510.ASAC_0117 3.221e-31 132.0 COG2820@1|root,arCOG01324@2157|Archaea,2XPX2@28889|Crenarchaeota 28889|Crenarchaeota F Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis udp - 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 - - - PNP_UDP_1 DYD1_k127_5255556_0 439235.Dalk_4040 2.052e-66 241.0 COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42S94@68525|delta/epsilon subdivisions,2WNCW@28221|Deltaproteobacteria,2MNBQ@213118|Desulfobacterales 1224|Proteobacteria C Cysteine-rich domain - - - - - - - - - - - - CCG,Fer4_8 DYD1_k127_5261732_3 1120948.KB903243_gene2469 8.558e-05 47.0 COG1960@1|root,COG1960@2|Bacteria,2I5JQ@201174|Actinobacteria,4E1PG@85010|Pseudonocardiales 201174|Actinobacteria I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_5261732_1 1499680.CCFE01000023_gene2581 6.193e-53 203.0 COG1960@1|root,COG1960@2|Bacteria,1UX6T@1239|Firmicutes,4IJKC@91061|Bacilli,1ZM73@1386|Bacillus 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_5261732_0 1125863.JAFN01000001_gene1136 1.781e-85 298.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,43B11@68525|delta/epsilon subdivisions,2X6F7@28221|Deltaproteobacteria 28221|Deltaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_5261732_2 7918.ENSLOCP00000007482 2.088e-07 55.0 COG2079@1|root,2QVEB@2759|Eukaryota,38H3S@33154|Opisthokonta,3BE3K@33208|Metazoa,3D143@33213|Bilateria,480P0@7711|Chordata,4961I@7742|Vertebrata,49UNK@7898|Actinopterygii 33208|Metazoa S Immunoresponsive gene 1 IRG1 GO:0000003,GO:0001817,GO:0001818,GO:0002237,GO:0002376,GO:0002507,GO:0002520,GO:0002682,GO:0002683,GO:0002684,GO:0002759,GO:0002760,GO:0002831,GO:0002832,GO:0002833,GO:0002920,GO:0002922,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006355,GO:0006629,GO:0006631,GO:0006950,GO:0006952,GO:0006955,GO:0007275,GO:0007565,GO:0007566,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009725,GO:0009889,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010646,GO:0010648,GO:0014070,GO:0016829,GO:0016830,GO:0016831,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019219,GO:0019222,GO:0019541,GO:0019679,GO:0019752,GO:0022414,GO:0023051,GO:0023057,GO:0031323,GO:0031325,GO:0031326,GO:0031347,GO:0031348,GO:0031664,GO:0031665,GO:0032088,GO:0032101,GO:0032102,GO:0032103,GO:0032479,GO:0032480,GO:0032496,GO:0032501,GO:0032502,GO:0032570,GO:0032787,GO:0032870,GO:0033993,GO:0034097,GO:0034121,GO:0034122,GO:0034135,GO:0034136,GO:0034143,GO:0034144,GO:0034341,GO:0034612,GO:0035456,GO:0035458,GO:0035690,GO:0042221,GO:0042493,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043433,GO:0043436,GO:0043900,GO:0043901,GO:0043902,GO:0044092,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044706,GO:0045087,GO:0045088,GO:0045824,GO:0046459,GO:0047547,GO:0047613,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048856,GO:0050727,GO:0050728,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051239,GO:0051241,GO:0051252,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070555,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071346,GO:0071347,GO:0071356,GO:0071383,GO:0071393,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0072573,GO:0080090,GO:0080134,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1903506,GO:2000112,GO:2000377,GO:2000379,GO:2001141 4.1.1.6 ko:K17724 ko00660,map00660 - R02243 RC00667 ko00000,ko00001,ko01000 - - - MmgE_PrpD DYD1_k127_5267155_6 1038866.KB902811_gene1833 7.57e-22 95.0 COG2984@1|root,COG2984@2|Bacteria 2|Bacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5267155_4 608506.COB47_2040 1.463e-25 113.0 COG1848@1|root,COG1848@2|Bacteria,1VHRP@1239|Firmicutes,24SGU@186801|Clostridia,42JCQ@68295|Thermoanaerobacterales 186801|Clostridia S Large family of predicted nucleotide-binding domains - - - - - - - - - - - - PIN DYD1_k127_5267155_7 643648.Slip_0213 2.171e-10 64.0 COG2002@1|root,COG2002@2|Bacteria,1VGCT@1239|Firmicutes,24UBR@186801|Clostridia 186801|Clostridia K toxin-antitoxin pair type II binding - - - - - - - - - - - - MazE_antitoxin DYD1_k127_5267155_5 406818.XBJ1_2672 8.142e-23 102.0 2E8X6@1|root,33378@2|Bacteria,1N0Q7@1224|Proteobacteria,1SBN0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Immunity protein 63 - - - - - - - - - - - - Imm63 DYD1_k127_5267155_8 189753.AXAS01000041_gene2534 3.842e-09 61.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5267155_9 1380394.JADL01000007_gene4451 0.0008146 43.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,2JVYF@204441|Rhodospirillales 204441|Rhodospirillales S COG0457 FOG TPR repeat - - - - - - - - - - - - - DYD1_k127_5267155_0 1108045.GORHZ_084_00430 1.337e-80 278.0 COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4GEP0@85026|Gordoniaceae 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_5267155_1 189753.AXAS01000041_gene2534 4.162e-79 277.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5267155_2 1297569.MESS2_1000038 8.236e-51 190.0 COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q Methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Ubie_methyltran DYD1_k127_5267155_3 263358.VAB18032_13455 3.105e-38 151.0 COG2320@1|root,COG2320@2|Bacteria,2GTS4@201174|Actinobacteria,4DEZ5@85008|Micromonosporales 201174|Actinobacteria S GrpB protein - - - - - - - - - - - - GrpB DYD1_k127_5270762_11 247490.KSU1_B0298 0.0001627 48.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 DYD1_k127_5270762_6 284031.JNXD01000025_gene367 6.689e-18 87.0 COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_5270762_10 608538.HTH_1212 4.345e-05 54.0 COG5424@1|root,COG5424@2|Bacteria 2|Bacteria H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ pqqC - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4 DYD1_k127_5270762_9 1205680.CAKO01000002_gene3024 1.14e-05 57.0 COG0715@1|root,COG0715@2|Bacteria,1QVUU@1224|Proteobacteria 1224|Proteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_5270762_8 273063.STK_26060 1.023e-07 62.0 COG5424@1|root,arCOG06031@2157|Archaea,2XRWB@28889|Crenarchaeota 28889|Crenarchaeota H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4,zf-C2H2_9 DYD1_k127_5270762_5 671143.DAMO_0790 8.75e-28 115.0 COG4118@1|root,COG4118@2|Bacteria 2|Bacteria D positive regulation of growth - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - PhdYeFM_antitox DYD1_k127_5270762_4 671143.DAMO_0789 1.338e-47 173.0 COG3744@1|root,COG3744@2|Bacteria,2NRIX@2323|unclassified Bacteria 2|Bacteria S PIN domain - - - - - - - - - - - - PIN DYD1_k127_5270762_3 189753.AXAS01000041_gene2534 4.215e-88 301.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5270762_1 1097668.BYI23_C003130 8.142e-146 479.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2WBWM@28216|Betaproteobacteria,1K6TM@119060|Burkholderiaceae 28216|Betaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - - - - - - - - - - UbiD DYD1_k127_5270762_0 926549.KI421517_gene931 3.504e-176 572.0 COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia 976|Bacteroidetes S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD1_k127_5270762_7 640511.BC1002_1399 4.745e-13 80.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,1K2JX@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM NMT1 THI5 like domain protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 DYD1_k127_5270762_2 392499.Swit_0904 2.278e-141 463.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,2K6JZ@204457|Sphingomonadales 204457|Sphingomonadales H Belongs to the UbiD family - - 4.1.1.98 ko:K03182,ko:K16874 ko00130,ko00365,ko01100,ko01110,ko01120,map00130,map00365,map01100,map01110,map01120 M00117 R04985,R04986,R10213 RC00391,RC03086 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_5276406_1 266117.Rxyl_0933 5.316e-83 281.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria 84995|Rubrobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_5276406_2 42256.RradSPS_2996 5.114e-42 157.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria 84995|Rubrobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_5276406_3 519989.ECTPHS_11632 2.016e-23 110.0 COG0730@1|root,COG0730@2|Bacteria,1RJXP@1224|Proteobacteria,1S5MM@1236|Gammaproteobacteria,1WYSR@135613|Chromatiales 135613|Chromatiales S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE DYD1_k127_5276406_0 1128421.JAGA01000003_gene2811 1.098e-144 468.0 COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria 2|Bacteria E Threonine synthase MA20_41710 - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_5276406_4 485913.Krac_9361 7.693e-11 63.0 COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi 200795|Chloroflexi C PFAM 6-phosphogluconate dehydrogenase NAD-binding - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD1_k127_5278210_2 1329516.JPST01000009_gene2076 0.0003514 53.0 COG3379@1|root,COG3379@2|Bacteria,1VHYF@1239|Firmicutes 1239|Firmicutes Q type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest DYD1_k127_5278210_1 1521187.JPIM01000097_gene2709 1.405e-13 84.0 COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2G90N@200795|Chloroflexi,376SX@32061|Chloroflexia 32061|Chloroflexia P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest DYD1_k127_5278210_0 765910.MARPU_02225 3.316e-35 140.0 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1WWJB@135613|Chromatiales 135613|Chromatiales E PFAM Amino acid-binding ACT - - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 DYD1_k127_5278533_4 391625.PPSIR1_19949 9.43e-80 278.0 COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9 DYD1_k127_5278533_9 1454004.AW11_01952 2.21e-19 93.0 COG0071@1|root,COG0071@2|Bacteria,1N0RH@1224|Proteobacteria,2VVUG@28216|Betaproteobacteria 28216|Betaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - - - - - - - - - - HSP20 DYD1_k127_5278533_1 288000.BBta_7794 4.049e-291 914.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2U0IK@28211|Alphaproteobacteria,3JTMI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD1_k127_5278533_6 671143.DAMO_1116 1.918e-57 213.0 COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria 2|Bacteria M Mannose-6-phosphate isomerase manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase DYD1_k127_5278533_3 398767.Glov_1013 3.113e-102 352.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_5278533_10 880073.Calab_0099 2.475e-17 83.0 COG0231@1|root,COG0231@2|Bacteria,2NPID@2323|unclassified Bacteria 2|Bacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD1_k127_5278533_11 1235793.C809_03754 1.874e-12 71.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,27J9W@186928|unclassified Lachnospiraceae 186801|Clostridia J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD1_k127_5278533_12 234267.Acid_3676 3.453e-11 64.0 COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria 57723|Acidobacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase - - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD1_k127_5278533_7 1260251.SPISAL_07535 2.909e-55 198.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1WWG3@135613|Chromatiales 135613|Chromatiales K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG DYD1_k127_5278533_2 1266925.JHVX01000003_gene514 3.891e-147 475.0 COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,372V2@32003|Nitrosomonadales 28216|Betaproteobacteria M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - Mur_ligase_M,PGA_cap DYD1_k127_5278533_13 1458357.BG58_20070 1.816e-06 53.0 2DD1F@1|root,2ZG56@2|Bacteria,1P83T@1224|Proteobacteria,2W5PB@28216|Betaproteobacteria,1K8XE@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1488) - - - - - - - - - - - - DUF1488 DYD1_k127_5278533_5 748247.AZKH_1502 1.882e-69 246.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KUWF@206389|Rhodocyclales 28216|Betaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins - - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD1_k127_5278533_8 272633.26454360 2.271e-36 143.0 COG0484@1|root,COG0484@2|Bacteria,3WSX8@544448|Tenericutes 544448|Tenericutes O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD1_k127_5278533_0 279714.FuraDRAFT_2622 8.811e-297 920.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KPV9@206351|Neisseriales 28216|Betaproteobacteria O Heat shock 70 kDa protein - - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD1_k127_5279545_5 189753.AXAS01000041_gene2534 2.222e-27 112.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5279545_3 189753.AXAS01000041_gene2534 2.653e-75 265.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5279545_2 189753.AXAS01000041_gene2534 4.176e-76 266.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5279545_0 189753.AXAS01000041_gene2534 1.238e-86 298.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5279545_6 1313172.YM304_23600 1.955e-05 52.0 COG2337@1|root,COG2337@2|Bacteria 2|Bacteria T Toxic component of a toxin-antitoxin (TA) module mazF3 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006355,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD1_k127_5279545_1 189753.AXAS01000012_gene4337 8.06e-82 283.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5279545_4 189753.AXAS01000041_gene2534 1.23e-69 248.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5291928_2 1192034.CAP_3169 2.936e-47 176.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2YWS8@29|Myxococcales 28221|Deltaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain mmgB - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N DYD1_k127_5291928_1 443218.AS9A_2778 1.569e-144 468.0 COG5274@1|root,COG5274@2|Bacteria,2HH9U@201174|Actinobacteria 201174|Actinobacteria CI Indoleamine 2,3-dioxygenase - - 1.13.11.52 ko:K00463 ko00380,ko01100,ko05143,map00380,map01100,map05143 M00038 R00678,R02702,R02909,R03628 RC00356 ko00000,ko00001,ko00002,ko01000 - - - IDO DYD1_k127_5291928_0 1128421.JAGA01000002_gene1751 1.966e-149 482.0 COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria 2|Bacteria E Cys/Met metabolism PLP-dependent enzyme metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 ko:K01739,ko:K01758,ko:K01760,ko:K01761 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - iNJ661.Rv1079 Cys_Met_Meta_PP DYD1_k127_5296161_7 1121405.dsmv_2371 6.562e-28 119.0 COG0454@1|root,COG0456@2|Bacteria,1N43K@1224|Proteobacteria,42VN3@68525|delta/epsilon subdivisions,2WRDJ@28221|Deltaproteobacteria,2MNCT@213118|Desulfobacterales 28221|Deltaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD1_k127_5296161_4 1068980.ARVW01000001_gene862 2.455e-76 263.0 COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4E2EI@85010|Pseudonocardiales 201174|Actinobacteria I Enoyl-CoA hydratase/isomerase echA5 - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_5296161_5 646529.Desaci_0696 3.698e-68 242.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,24ZF2@186801|Clostridia,264GX@186807|Peptococcaceae 186801|Clostridia I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_5296161_3 1244869.H261_10452 2.091e-78 271.0 COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria,2JU12@204441|Rhodospirillales 204441|Rhodospirillales S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5296161_2 1048834.TC41_1120 1.779e-78 270.0 COG1028@1|root,COG1028@2|Bacteria,1TR8Y@1239|Firmicutes,4HFAC@91061|Bacilli,279AR@186823|Alicyclobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family - - - ko:K07535 ko00362,ko01120,ko01220,map00362,map01120,map01220 M00540 R05582 RC00154 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 DYD1_k127_5296161_6 909663.KI867150_gene1130 5.551e-66 235.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42R04@68525|delta/epsilon subdivisions,2WMZ2@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM ATPase, BadF BadG BcrA BcrD type - - - - - - - - - - - - BcrAD_BadFG DYD1_k127_5296161_1 398767.Glov_2399 5.353e-81 283.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales 28221|Deltaproteobacteria I BadF/BadG/BcrA/BcrD ATPase family yjiL - - - - - - - - - - - BcrAD_BadFG DYD1_k127_5296161_0 316055.RPE_0607 5.675e-88 307.0 COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria 28211|Alphaproteobacteria E benzoyl-CoA reductase - - 1.3.7.8 ko:K04113 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D DYD1_k127_5296161_8 929506.CbC4_0488 0.0001341 45.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae 186801|Clostridia E 2-hydroxyglutaryl-CoA dehydratase, D-component hgdB - 1.3.7.8,4.2.1.157,4.2.1.54 ko:K04112,ko:K20026,ko:K20627 ko00362,ko00640,ko00643,ko01100,ko01120,ko01220,map00362,map00640,map00643,map01100,map01120,map01220 M00541 R02451,R02963 RC00002,RC00818,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D DYD1_k127_5303107_1 671143.DAMO_1883 1.054e-84 287.0 COG3638@1|root,COG3638@2|Bacteria,2NPDZ@2323|unclassified Bacteria 2|Bacteria P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran DYD1_k127_5303107_0 671143.DAMO_1882 4.093e-118 386.0 COG3221@1|root,COG3221@2|Bacteria,2NRED@2323|unclassified Bacteria 2|Bacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd DYD1_k127_5303107_2 671143.DAMO_0804 1.113e-68 244.0 COG0583@1|root,COG0583@2|Bacteria,2NPS6@2323|unclassified Bacteria 2|Bacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate DYD1_k127_5303107_3 330214.NIDE1059 8.325e-66 238.0 COG0404@1|root,COG0404@2|Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT - 1.5.99.5,2.1.2.10 ko:K00605,ko:K06980,ko:K22086 ko00260,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200 M00532 R00609,R01221,R02300,R04125 RC00022,RC00069,RC00183,RC00190,RC00557,RC02834 ko00000,ko00001,ko00002,ko01000,ko03016 - - - GCV_T,GCV_T_C DYD1_k127_5303107_6 330214.NIDE2482 1.003e-28 118.0 COG2146@1|root,COG2146@2|Bacteria,3J1E7@40117|Nitrospirae 40117|Nitrospirae P Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 1.7.1.15 ko:K00363,ko:K05710 ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220 M00530,M00545 R00787,R06782,R06783 RC00098,RC00176 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske DYD1_k127_5303107_7 1157490.EL26_03370 7.083e-23 101.0 COG1225@1|root,COG1225@2|Bacteria,1V6MU@1239|Firmicutes,4HK8J@91061|Bacilli,27A0F@186823|Alicyclobacillaceae 91061|Bacilli O Redoxin - - - - - - - - - - - - AhpC-TSA DYD1_k127_5303107_8 1121382.JQKG01000017_gene1882 1.092e-08 58.0 COG0450@1|root,COG0450@2|Bacteria,1WJFK@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O Redoxin - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA DYD1_k127_5303107_5 671143.DAMO_3020 2.51e-60 213.0 COG1051@1|root,COG2138@1|root,COG1051@2|Bacteria,COG2138@2|Bacteria,2NPZ5@2323|unclassified Bacteria 2|Bacteria F NUDIX domain cbiX - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 ko:K00077,ko:K01092,ko:K03574,ko:K03795 ko00521,ko00562,ko00770,ko00860,ko01100,ko01110,ko01120,ko04070,map00521,map00562,map00770,map00860,map01100,map01110,map01120,map04070 M00119,M00131 R01185,R01186,R01187,R02472,R05807 RC00078,RC00726,RC01012 ko00000,ko00001,ko00002,ko01000,ko03400 - - - CbiX,NUDIX DYD1_k127_5303107_4 330214.NIDE1522 3.622e-61 218.0 COG0637@1|root,COG0637@2|Bacteria,3J15X@40117|Nitrospirae 40117|Nitrospirae S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 DYD1_k127_5303107_9 109760.SPPG_06668T0 0.0007844 42.0 COG1028@1|root,KOG0725@2759|Eukaryota 2759|Eukaryota IQ oxidation-reduction process - - - - - - - - - - - - adh_short DYD1_k127_5306022_5 251229.Chro_0899 4.458e-09 62.0 2BFTT@1|root,329NS@2|Bacteria,1GPAJ@1117|Cyanobacteria,3VNDF@52604|Pleurocapsales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5306022_2 1538644.KO02_13870 1.276e-22 100.0 2EQN7@1|root,33I86@2|Bacteria,4NTSW@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_5306022_4 1227360.C176_21211 3.465e-15 87.0 2CCSE@1|root,32RWB@2|Bacteria,1VCZC@1239|Firmicutes,4HMWJ@91061|Bacilli,26HM8@186818|Planococcaceae 91061|Bacilli S Domain of unknown function (DUF4304) - - - - - - - - - - - - DUF4304 DYD1_k127_5306022_1 485913.Krac_3471 3.237e-34 138.0 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity - - 3.1.3.85,5.4.2.11,5.4.2.12 ko:K01834,ko:K15634,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 DYD1_k127_5306022_0 296591.Bpro_0189 1.002e-86 288.0 COG3791@1|root,COG3791@2|Bacteria,1RFBP@1224|Proteobacteria,2VQN8@28216|Betaproteobacteria,4AE1T@80864|Comamonadaceae 28216|Betaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD1_k127_5307278_1 234267.Acid_1486 1.217e-121 399.0 COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria 57723|Acidobacteria E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B DYD1_k127_5307278_2 999550.KI421507_gene2808 2.745e-121 404.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria 28211|Alphaproteobacteria H glutamate--cysteine ligase gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 DYD1_k127_5307278_4 218284.CCDN010000002_gene2288 3.615e-83 289.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - DUF4309,Glyco_hydro_3 DYD1_k127_5307278_0 330214.NIDE0029 1.326e-228 727.0 COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria 2|Bacteria KT transcription factor binding fhlA GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009 ko02020,ko02025,ko05132,map02020,map02025,map05132 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat DYD1_k127_5307278_3 1040987.AZUY01000001_gene2628 3.382e-91 306.0 COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,2TV6T@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase SDR - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_5307278_5 479433.Caci_7062 1.283e-59 214.0 COG2258@1|root,COG2258@2|Bacteria 2|Bacteria C MOSC domain - - - - - - - - - - - - MOSC DYD1_k127_5307278_8 743721.Psesu_2825 2.365e-47 178.0 COG4270@1|root,COG4270@2|Bacteria,1N2NG@1224|Proteobacteria,1SA7N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - DYD1_k127_5307278_7 492774.JQMB01000014_gene1510 2.935e-52 188.0 COG0346@1|root,COG0346@2|Bacteria,1NZNJ@1224|Proteobacteria,2UTNS@28211|Alphaproteobacteria,4BEWN@82115|Rhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_5307278_13 330214.NIDE3498 0.0004591 45.0 COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria 2|Bacteria KT transcription factor binding fhlA GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - ko:K02584,ko:K12146,ko:K12266,ko:K15836,ko:K21009 ko02020,ko02025,ko05132,map02020,map02025,map05132 - - - ko00000,ko00001,ko03000 - - - GAF,GAF_2,GAF_3,HTH_8,Sigma54_activat DYD1_k127_5307278_11 42256.RradSPS_2858 3.219e-22 102.0 COG4270@1|root,COG4270@2|Bacteria,2GQJP@201174|Actinobacteria 201174|Actinobacteria S DoxX-like family - - - - - - - - - - - - DoxX_2 DYD1_k127_5307278_10 1173023.KE650771_gene4317 3.405e-41 154.0 COG0346@1|root,COG0346@2|Bacteria,1G62I@1117|Cyanobacteria 1117|Cyanobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_5307278_9 460265.Mnod_0258 5.654e-47 171.0 COG3791@1|root,COG3791@2|Bacteria,1N6S5@1224|Proteobacteria,2UG0P@28211|Alphaproteobacteria,1JZ9K@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM glutathione-dependent formaldehyde-activating GFA - - - - - - - - - - - - GFA DYD1_k127_5307278_12 1068978.AMETH_0378 8.461e-19 91.0 2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria,4E3RM@85010|Pseudonocardiales 201174|Actinobacteria S F420H(2)-dependent quinone reductase - - - - - - - - - - - - F420H2_quin_red DYD1_k127_5307278_6 1254432.SCE1572_32740 4.834e-57 205.0 COG0625@1|root,COG3631@1|root,COG0625@2|Bacteria,COG3631@2|Bacteria,1N3UG@1224|Proteobacteria 1224|Proteobacteria O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 DYD1_k127_5312995_0 305700.B447_02541 1.515e-60 226.0 COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,2VM18@28216|Betaproteobacteria,2KZHC@206389|Rhodocyclales 206389|Rhodocyclales S Pfam:AmoA - - - ko:K07120 - - - - ko00000 - - - AbrB DYD1_k127_5312995_1 237368.SCABRO_01842 1.04e-37 147.0 COG1047@1|root,COG1047@2|Bacteria,2J1AR@203682|Planctomycetes 203682|Planctomycetes O FKBP-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C DYD1_k127_5321244_17 196490.AUEZ01000002_gene4197 5.33e-30 122.0 COG0479@1|root,COG0479@2|Bacteria,1N210@1224|Proteobacteria,2UDMB@28211|Alphaproteobacteria,3K42F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2_3 DYD1_k127_5321244_14 401526.TcarDRAFT_1449 2.784e-35 146.0 COG1099@1|root,COG1099@2|Bacteria,1V5KM@1239|Firmicutes,4H4YQ@909932|Negativicutes 909932|Negativicutes S with the TIM-barrel fold - - - - - - - - - - - - - DYD1_k127_5321244_1 1499967.BAYZ01000076_gene754 6.801e-167 537.0 COG0641@1|root,COG0641@2|Bacteria 2|Bacteria C radical SAM aslB - - ko:K06871 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM DYD1_k127_5321244_13 1268068.PG5_42060 6.134e-44 171.0 COG0726@1|root,COG3195@1|root,COG0726@2|Bacteria,COG3195@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria 1236|Gammaproteobacteria G deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 DYD1_k127_5321244_15 525904.Tter_1812 6.403e-33 132.0 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity - - - - - - - - - - - - CBS,GGDEF DYD1_k127_5321244_3 264732.Moth_0262 3.996e-147 472.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales 186801|Clostridia C TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD1_k127_5321244_2 309803.CTN_0395 2.605e-154 499.0 COG0205@1|root,COG0205@2|Bacteria,2GC8H@200918|Thermotogae 200918|Thermotogae F Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK DYD1_k127_5321244_29 644966.Tmar_1500 3.578e-06 49.0 COG2259@1|root,COG2259@2|Bacteria,1V38Q@1239|Firmicutes,25DF1@186801|Clostridia 186801|Clostridia S DoxX - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX DYD1_k127_5321244_25 1449351.RISW2_01135 1.499e-09 64.0 COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,2UCF1@28211|Alphaproteobacteria,4KN3C@93682|Roseivivax 28211|Alphaproteobacteria T Prokaryotic dksA/traR C4-type zinc finger dskA - - - - - - - - - - - zf-dskA_traR DYD1_k127_5321244_18 247490.KSU1_C0105 2.412e-27 116.0 COG0517@1|root,COG0517@2|Bacteria,2J4UJ@203682|Planctomycetes 203682|Planctomycetes S Domain in cystathionine beta-synthase and other proteins. - - - ko:K04767 - - - - ko00000 - - - CBS DYD1_k127_5321244_21 1304888.ATWF01000001_gene1072 1.629e-18 91.0 COG0517@1|root,COG0517@2|Bacteria,2GEQ8@200930|Deferribacteres 200930|Deferribacteres S Domain in cystathionine beta-synthase and other proteins. - - - ko:K04767 - - - - ko00000 - - - ACT,CBS DYD1_k127_5321244_20 575540.Isop_2672 2.054e-20 96.0 COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes 203682|Planctomycetes T Universal stress protein - - - - - - - - - - - - Usp DYD1_k127_5321244_4 861299.J421_3786 7.458e-135 441.0 COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase DYD1_k127_5321244_0 118168.MC7420_794 1.381e-318 996.0 COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria,1H7CT@1150|Oscillatoriales 1117|Cyanobacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N DYD1_k127_5321244_19 1267211.KI669560_gene1579 1.423e-24 108.0 COG1764@1|root,COG1764@2|Bacteria,4PIVZ@976|Bacteroidetes,1IYQC@117747|Sphingobacteriia 976|Bacteroidetes O OsmC-like protein - - - - - - - - - - - - OsmC DYD1_k127_5321244_5 1382359.JIAL01000001_gene2087 1.885e-129 424.0 COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria,2JHRQ@204432|Acidobacteriia 204432|Acidobacteriia E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_5321244_8 1128421.JAGA01000001_gene2435 8.587e-91 312.0 COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria 2|Bacteria S VIT family - - - - - - - - - - - - Rubrerythrin,VIT1 DYD1_k127_5321244_11 926561.KB900617_gene1579 3.638e-55 213.0 COG1388@1|root,COG1785@1|root,COG1388@2|Bacteria,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,248GG@186801|Clostridia,3WAZT@53433|Halanaerobiales 186801|Clostridia P Belongs to the alkaline phosphatase family - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase DYD1_k127_5321244_9 671143.DAMO_0834 7.522e-67 234.0 COG1183@1|root,COG1183@2|Bacteria,2NR1K@2323|unclassified Bacteria 2|Bacteria I phosphatidylcholine synthase activity pcs GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 ko:K01004,ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800,R05794 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD1_k127_5321244_16 1502851.FG93_03963 1.92e-32 135.0 COG0625@1|root,COG0625@2|Bacteria,1RC4Y@1224|Proteobacteria,2U6JK@28211|Alphaproteobacteria,3JVU5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 DYD1_k127_5321244_12 667632.KB890165_gene2303 1.854e-47 184.0 COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2VMRR@28216|Betaproteobacteria,1K5FQ@119060|Burkholderiaceae 28216|Betaproteobacteria V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - - DYD1_k127_5321244_26 649638.Trad_0410 3.156e-09 66.0 COG0723@1|root,COG0723@2|Bacteria,1WI5B@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C PFAM Rieske 2Fe-2S domain - - - - - - - - - - - - Rieske DYD1_k127_5321244_28 446469.Sked_15690 7.287e-08 61.0 COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria 201174|Actinobacteria C c reductase qcrA - - ko:K03890 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002 - - - Rieske DYD1_k127_5321244_6 204669.Acid345_3483 5.971e-112 385.0 COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,3Y46R@57723|Acidobacteria,2JICT@204432|Acidobacteriia 204432|Acidobacteriia O PA domain - - - - - - - - - - - - PA,Peptidase_M28 DYD1_k127_5321244_23 1286171.EAL2_c00450 2.891e-14 74.0 COG0695@1|root,COG0695@2|Bacteria,1UF2R@1239|Firmicutes,25NBW@186801|Clostridia,25Z45@186806|Eubacteriaceae 186801|Clostridia O Glutaredoxin - - - - - - - - - - - - Glutaredoxin DYD1_k127_5321244_7 102129.Lepto7375DRAFT_3264 1.61e-92 315.0 COG2220@1|root,COG2220@2|Bacteria,1G2CA@1117|Cyanobacteria,1HEXT@1150|Oscillatoriales 1117|Cyanobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 DYD1_k127_5321244_10 1101190.ARWB01000001_gene117 4.974e-58 212.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,36XKT@31993|Methylocystaceae 28211|Alphaproteobacteria Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_5321244_27 1441629.PCH70_25130 6.57e-09 64.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,1RPGK@1236|Gammaproteobacteria,1Z5GI@136849|Pseudomonas syringae group 1236|Gammaproteobacteria Q Dienelactone hydrolase yghX - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_5321244_22 1122605.KB893649_gene3740 7.915e-18 85.0 COG3540@1|root,COG3540@2|Bacteria,4PIVJ@976|Bacteroidetes,1IZN8@117747|Sphingobacteriia 976|Bacteroidetes P PhoD-like phosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD DYD1_k127_5321244_24 595460.RRSWK_03617 5.825e-11 62.0 COG3540@1|root,COG3540@2|Bacteria,2J1QH@203682|Planctomycetes 203682|Planctomycetes P PhoD-like phosphatase - - - - - - - - - - - - PhoD DYD1_k127_5322226_0 426117.M446_1228 6.466e-176 563.0 COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,1JX9Q@119045|Methylobacteriaceae 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD1_k127_5322226_7 118161.KB235922_gene2672 5.574e-29 121.0 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity - - - ko:K04767 - - - - ko00000 - - - CBS DYD1_k127_5322226_3 1380390.JIAT01000012_gene3035 3.352e-50 187.0 COG0412@1|root,COG0412@2|Bacteria 2|Bacteria Q carboxymethylenebutenolidase activity - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_5322226_14 1394178.AWOO02000059_gene623 9.177e-07 61.0 COG0715@1|root,COG0715@2|Bacteria,2IGX1@201174|Actinobacteria 201174|Actinobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_5322226_2 469610.HMPREF0189_02337 1.016e-58 215.0 COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,2VJI2@28216|Betaproteobacteria,1KJ2S@119065|unclassified Burkholderiales 28216|Betaproteobacteria EJ Asparaginase ansB - 3.5.1.1,3.5.1.38 ko:K01424,ko:K05597 ko00220,ko00250,ko00460,ko00471,ko01100,ko01110,ko02020,map00220,map00250,map00460,map00471,map01100,map01110,map02020 - R00256,R00485,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase DYD1_k127_5322226_1 1122604.JONR01000001_gene1774 3.087e-65 231.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1X3R8@135614|Xanthomonadales 1236|Gammaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate - - - - - - - - - - - - Pantoate_transf DYD1_k127_5322226_16 1205680.CAKO01000002_gene3085 0.0001189 50.0 2DPNC@1|root,32UMG@2|Bacteria,1N0XW@1224|Proteobacteria,2UVTT@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - - - - - - - - - - LigA DYD1_k127_5322226_5 1223544.GSI01S_20_00170 3.175e-46 177.0 COG3885@1|root,COG3885@2|Bacteria 2|Bacteria S ferrous iron binding amrA - - ko:K06990,ko:K15755 ko00621,ko01100,ko01120,ko01220,map00621,map01100,map01120,map01220 M00544 R05415 RC01306 br01602,ko00000,ko00001,ko00002,ko01000,ko04812 - - - AMMECR1,LigB DYD1_k127_5322226_6 1173022.Cri9333_1541 1.434e-41 167.0 COG4447@1|root,COG4447@2|Bacteria,1GAGV@1117|Cyanobacteria,1HF4J@1150|Oscillatoriales 1117|Cyanobacteria S cellulose binding - - - - - - - - - - - - BNR DYD1_k127_5322226_4 675635.Psed_2070 1.518e-48 187.0 COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4E9P4@85010|Pseudonocardiales 201174|Actinobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD1_k127_5322226_11 1245469.S58_43570 9.476e-11 73.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,3JW2Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_5322226_13 376733.IT41_11760 3.042e-07 58.0 COG0346@1|root,COG0346@2|Bacteria,1RIN8@1224|Proteobacteria,2U9WM@28211|Alphaproteobacteria,2PWWG@265|Paracoccus 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_5322226_10 1242864.D187_003169 3.8e-11 70.0 COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,42TP3@68525|delta/epsilon subdivisions,2WR14@28221|Deltaproteobacteria,2Z032@29|Myxococcales 28221|Deltaproteobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct DYD1_k127_5322226_12 1245469.S58_43570 4.115e-10 70.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,3JW2Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_5322226_15 67373.JOBF01000003_gene501 4.944e-06 56.0 COG0346@1|root,COG0346@2|Bacteria,2IHXI@201174|Actinobacteria 201174|Actinobacteria E glyoxalase bleomycin resistance protein dioxygenase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD1_k127_5322226_9 1120948.KB903218_gene1877 1.235e-18 91.0 COG3193@1|root,COG3193@2|Bacteria,2IK20@201174|Actinobacteria,4E7NC@85010|Pseudonocardiales 201174|Actinobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading DYD1_k127_5322226_8 1382356.JQMP01000003_gene1735 1.207e-26 119.0 COG0235@1|root,COG0235@2|Bacteria,2G63H@200795|Chloroflexi 200795|Chloroflexi G Class II Aldolase and Adducin N-terminal domain - - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II DYD1_k127_5334699_8 1429916.X566_10065 4.282e-36 151.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria,3JR8H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Major Facilitator Superfamily MA20_02120 - - - - - - - - - - - MFS_1 DYD1_k127_5334699_11 56780.SYN_03077 6.002e-26 113.0 COG5652@1|root,COG5652@2|Bacteria,1PUUC@1224|Proteobacteria,43F3B@68525|delta/epsilon subdivisions,2X381@28221|Deltaproteobacteria,2MSC7@213462|Syntrophobacterales 28221|Deltaproteobacteria S VanZ like family - - - - - - - - - - - - VanZ DYD1_k127_5334699_10 290318.Cvib_1163 4.019e-28 121.0 COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi 1090|Chlorobi M PFAM OmpA MotB domain protein - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD1_k127_5334699_13 1121382.JQKG01000011_gene576 1.617e-12 70.0 2DNS7@1|root,32YWC@2|Bacteria,1WKTD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_5334699_0 215803.DB30_2329 5.839e-142 483.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1NR2V@1224|Proteobacteria,42YIK@68525|delta/epsilon subdivisions,2WUNG@28221|Deltaproteobacteria 28221|Deltaproteobacteria MV MacB-like periplasmic core domain lolE-2 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_5334699_5 1123508.JH636444_gene5483 3.313e-74 255.0 COG1136@1|root,COG1136@2|Bacteria,2IZ2F@203682|Planctomycetes 203682|Planctomycetes V ABC-type antimicrobial peptide transport system, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_5334699_12 1210884.HG799464_gene10802 3.138e-20 96.0 COG1547@1|root,COG1547@2|Bacteria,2J0XW@203682|Planctomycetes 203682|Planctomycetes S Domain of unknown function (DUF309) - - - ko:K09763 - - - - ko00000 - - - DUF309 DYD1_k127_5334699_4 443144.GM21_2158 2.996e-75 271.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,43U10@69541|Desulfuromonadales 28221|Deltaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr DYD1_k127_5334699_6 44454.NF84_12460 5.861e-51 194.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_5334699_3 1173028.ANKO01000224_gene1260 2.532e-76 270.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 1117|Cyanobacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5334699_7 1121949.AQXT01000002_gene571 4.271e-41 165.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,43Z36@69657|Hyphomonadaceae 28211|Alphaproteobacteria V membrane fusion protein - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_D23 DYD1_k127_5334699_2 1408473.JHXO01000008_gene2724 7.136e-81 291.0 COG0477@1|root,COG2814@2|Bacteria,4NG27@976|Bacteroidetes,2FNG3@200643|Bacteroidia 976|Bacteroidetes P major facilitator superfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 DYD1_k127_5334699_9 1324957.K933_12885 1.827e-32 140.0 arCOG08113@1|root,arCOG08113@2157|Archaea,2XV1B@28890|Euryarchaeota,23TAX@183963|Halobacteria 183963|Halobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - BNR DYD1_k127_5334699_1 1051632.TPY_2012 1.583e-125 428.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis 186801|Clostridia C Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD1_k127_5335593_7 278963.ATWD01000001_gene3208 4.712e-26 120.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y2IQ@57723|Acidobacteria,2JHWZ@204432|Acidobacteriia 204432|Acidobacteriia T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_9 DYD1_k127_5335593_0 290397.Adeh_2304 3.019e-233 746.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.3,1.8.5.5 ko:K07306,ko:K08352 ko00920,ko01120,map00920,map01120 - R09501,R10149 RC02555,RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.3,5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_5335593_6 237368.SCABRO_03846 9.498e-39 156.0 COG3009@1|root,COG3009@2|Bacteria 2|Bacteria Q Protein conserved in bacteria - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux DYD1_k127_5335593_5 338963.Pcar_2751 2.226e-76 269.0 COG1463@1|root,COG1463@2|Bacteria,1MYEF@1224|Proteobacteria,42SPY@68525|delta/epsilon subdivisions,2WP3D@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q Mammalian cell entry related domain protein - - - ko:K02067,ko:K06192 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD1_k127_5335593_3 237368.SCABRO_03848 2.29e-104 344.0 COG1127@1|root,COG1127@2|Bacteria,2J2WI@203682|Planctomycetes 203682|Planctomycetes Q ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD1_k127_5335593_2 237368.SCABRO_03849 4.185e-127 417.0 COG0767@1|root,COG0767@2|Bacteria,2IX01@203682|Planctomycetes 203682|Planctomycetes Q Belongs to the MlaE permease family - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD1_k127_5335593_8 398527.Bphyt_1487 8.817e-10 66.0 COG0346@1|root,COG0346@2|Bacteria,1QVY4@1224|Proteobacteria,2VY37@28216|Betaproteobacteria,1K58Q@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase DYD1_k127_5335593_1 886293.Sinac_4912 3.669e-138 450.0 COG1533@1|root,COG1533@2|Bacteria,2IX0U@203682|Planctomycetes 203682|Planctomycetes L Radical SAM - - - - - - - - - - - - Radical_SAM DYD1_k127_5335593_9 1121448.DGI_1108 0.0002622 49.0 2ECCP@1|root,336AZ@2|Bacteria,1N9PN@1224|Proteobacteria,42W93@68525|delta/epsilon subdivisions,2WRXB@28221|Deltaproteobacteria,2MCH8@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - Rho_N DYD1_k127_5335593_4 478741.JAFS01000001_gene1393 4.224e-82 278.0 COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia,37GJA@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD DYD1_k127_5359549_8 179408.Osc7112_5447 5.813e-28 115.0 COG2154@1|root,COG2154@2|Bacteria,1G6T6@1117|Cyanobacteria,1HBVE@1150|Oscillatoriales 1117|Cyanobacteria H pterin-4-alpha-carbinolamine dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a DYD1_k127_5359549_7 469371.Tbis_2522 7.896e-45 176.0 COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4EEF0@85010|Pseudonocardiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_5359549_2 1303518.CCALI_01076 7.896e-125 417.0 COG0405@1|root,COG0405@2|Bacteria 2|Bacteria E Gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD1_k127_5359549_6 1231391.AMZF01000003_gene3182 1.406e-47 184.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2WG6Y@28216|Betaproteobacteria 28216|Betaproteobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_5359549_10 172088.AUGA01000001_gene6719 1.412e-11 76.0 COG2159@1|root,COG2159@2|Bacteria,1MVTS@1224|Proteobacteria,2TU78@28211|Alphaproteobacteria,3JT24@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase MA20_19315 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_5359549_9 706587.Desti_2842 4.189e-13 71.0 2EUYT@1|root,33NE0@2|Bacteria,1P79U@1224|Proteobacteria,432X2@68525|delta/epsilon subdivisions,2WXB8@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5359549_1 335543.Sfum_0068 9.203e-234 743.0 COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MR6X@213462|Syntrophobacterales 28221|Deltaproteobacteria J Elongation factor Tu domain 2 fusA-1 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_5359549_3 1278073.MYSTI_03801 2.083e-99 330.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2YTUR@29|Myxococcales 28221|Deltaproteobacteria F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1986 Pan_kinase DYD1_k127_5359549_5 243231.GSU1935 2.955e-63 226.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,43T0U@69541|Desulfuromonadales 28221|Deltaproteobacteria H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 DYD1_k127_5359549_4 429009.Adeg_1872 2.191e-86 294.0 COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,42F8G@68295|Thermoanaerobacterales 186801|Clostridia H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS12010 QRPTase_C,QRPTase_N DYD1_k127_5359549_0 269799.Gmet_0956 1.088e-279 880.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43TAT@69541|Desulfuromonadales 28221|Deltaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 DYD1_k127_5382268_3 273057.SSO1184 2.961e-24 110.0 COG1335@1|root,arCOG01943@2157|Archaea,2XRQA@28889|Crenarchaeota 28889|Crenarchaeota Q Isochorismatase family entB-like1 - - - - - - - - - - - Isochorismatase DYD1_k127_5382268_1 1190606.AJYG01000074_gene169 1.74e-130 431.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,1RPPC@1236|Gammaproteobacteria,1XSDQ@135623|Vibrionales 135623|Vibrionales P ABC-type Fe3 transport system, periplasmic component - - - - - - - - - - - - SBP_bac_6 DYD1_k127_5382268_0 1392838.AWNM01000006_gene2445 2.069e-165 537.0 COG1178@1|root,COG1178@2|Bacteria,1R0MN@1224|Proteobacteria,2VK7P@28216|Betaproteobacteria,3T76X@506|Alcaligenaceae 28216|Betaproteobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_5382268_2 644966.Tmar_0709 1.082e-98 332.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCDT@538999|Clostridiales incertae sedis 186801|Clostridia P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - - ABC_tran,TOBE_2 DYD1_k127_5388330_16 696747.NIES39_O01850 5.909e-10 65.0 COG3409@1|root,COG3409@2|Bacteria,1G7HF@1117|Cyanobacteria,1HBGU@1150|Oscillatoriales 1117|Cyanobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 DYD1_k127_5388330_15 76114.ebA6372 1.065e-17 90.0 2C5P4@1|root,3310H@2|Bacteria,1N6V1@1224|Proteobacteria,2VVVI@28216|Betaproteobacteria,2KXKC@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD1_k127_5388330_13 671143.DAMO_1668 2.208e-53 198.0 COG3794@1|root,COG3794@2|Bacteria,2NR3M@2323|unclassified Bacteria 2|Bacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - CarboxypepD_reg,fn3_3 DYD1_k127_5388330_12 671143.DAMO_1672 6.218e-60 211.0 COG0723@1|root,COG0723@2|Bacteria,2NRUZ@2323|unclassified Bacteria 2|Bacteria C Rieske [2Fe-2S] domain - - 1.10.9.1 ko:K02636,ko:K03886 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00151,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske DYD1_k127_5388330_14 414996.IL38_10965 1.122e-38 150.0 2AMUZ@1|root,31CRP@2|Bacteria,2HFYM@201174|Actinobacteria,40A6A@622450|Actinopolysporales 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_5388330_17 1041522.MCOL_V210695 8.84e-10 66.0 COG1463@1|root,COG1463@2|Bacteria,2GWJT@201174|Actinobacteria,233Q0@1762|Mycobacteriaceae 201174|Actinobacteria Q MCE family - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - Mce4_CUP1,MlaD DYD1_k127_5388330_8 706587.Desti_4373 2.826e-103 352.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MQRK@213462|Syntrophobacterales 28221|Deltaproteobacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD,SDH_sah DYD1_k127_5388330_10 443152.MDG893_15295 1.707e-61 225.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5388330_3 1144310.PMI07_005586 9.282e-145 484.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,4BCQJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA,TctB DYD1_k127_5388330_6 1173023.KE650771_gene1917 6.966e-118 390.0 COG0053@1|root,COG0053@2|Bacteria,1G361@1117|Cyanobacteria 1117|Cyanobacteria P TIGRFAM cation diffusion facilitator family transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer DYD1_k127_5388330_0 497964.CfE428DRAFT_6496 8.457e-268 835.0 COG3387@1|root,COG3387@2|Bacteria,46SD5@74201|Verrucomicrobia 74201|Verrucomicrobia G PFAM glycoside hydrolase 15-related - - - - - - - - - - - - Glyco_hydro_15 DYD1_k127_5388330_18 237368.SCABRO_03171 3.433e-05 48.0 COG4206@1|root,COG4206@2|Bacteria,2IY7Z@203682|Planctomycetes 203682|Planctomycetes H TonB-dependent Receptor Plug Domain - - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec DYD1_k127_5388330_5 261292.Nit79A3_1589 9.867e-121 400.0 COG2211@1|root,COG2211@2|Bacteria,1NR4C@1224|Proteobacteria,2W1HW@28216|Betaproteobacteria 28216|Betaproteobacteria G MFS_1 like family - - - - - - - - - - - - MFS_1 DYD1_k127_5388330_2 644282.Deba_0199 1.248e-161 520.0 COG1215@1|root,COG1215@2|Bacteria,1QVA1@1224|Proteobacteria,43BP8@68525|delta/epsilon subdivisions,2X70I@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM Glycosyl transferase family 2 - - 2.4.1.268 ko:K21349 - - - - ko00000,ko01000 - GT81 - Glycos_transf_2 DYD1_k127_5388330_1 1128421.JAGA01000003_gene2709 1.962e-162 532.0 COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups gpgS - 2.4.1.266,2.4.1.268 ko:K09118,ko:K13693,ko:K21349 - - - - ko00000,ko01000,ko01003 - GT81 - Glycos_transf_2,Usp DYD1_k127_5388330_11 330214.NIDE4204 2.533e-61 222.0 COG3769@1|root,COG3769@2|Bacteria 2|Bacteria S mannosylglycerate metabolic process mpgP GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 ko:K05947,ko:K07026 ko00051,map00051 - R05768,R05790 RC00005,RC00017,RC00397,RC02748 ko00000,ko00001,ko01000,ko01003 - - - Hydrolase_3 DYD1_k127_5388330_7 264732.Moth_1625 1.583e-103 346.0 COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales 186801|Clostridia F Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C DYD1_k127_5388330_4 1121430.JMLG01000005_gene717 2.095e-144 480.0 COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,260IK@186807|Peptococcaceae 186801|Clostridia J Elongation factor Tu domain 2 selB - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 DYD1_k127_5388330_9 1123371.ATXH01000011_gene94 2.842e-102 341.0 COG1921@1|root,COG1921@2|Bacteria,2GHB4@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria E Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - SelA DYD1_k127_5416713_2 338963.Pcar_0326 2.999e-161 516.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,43S2V@69541|Desulfuromonadales 28221|Deltaproteobacteria J Seryl-tRNA synthetase N-terminal domain serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAF987.Gmet_3528 Seryl_tRNA_N,tRNA-synt_2b DYD1_k127_5416713_6 1125863.JAFN01000001_gene2289 2.577e-31 126.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 DYD1_k127_5416713_5 1430331.EP10_16885 1.017e-56 206.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1WF7A@129337|Geobacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII DYD1_k127_5416713_7 671143.DAMO_0811 3.284e-23 101.0 COG0721@1|root,COG0721@2|Bacteria,2NPXC@2323|unclassified Bacteria 2|Bacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln DYD1_k127_5416713_0 671143.DAMO_0810 2.158e-198 629.0 COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria 2|Bacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD1_k127_5416713_1 1121405.dsmv_2747 2.271e-190 605.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2MIIZ@213118|Desulfobacterales 28221|Deltaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey DYD1_k127_5416713_3 338963.Pcar_2006 7.4e-123 410.0 COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria,43SA6@69541|Desulfuromonadales 28221|Deltaproteobacteria O ATPases associated with a variety of cellular activities - - - - - - - - - - - - AAA DYD1_k127_5416713_4 880073.Calab_2887 3.399e-82 288.0 COG2204@1|root,COG2204@2|Bacteria,2NQHI@2323|unclassified Bacteria 2|Bacteria T Sigma-54 interaction domain - - - ko:K02481,ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5416713_8 1499967.BAYZ01000003_gene5836 7.165e-15 85.0 COG0457@1|root,COG3577@1|root,COG0457@2|Bacteria,COG3577@2|Bacteria 2|Bacteria S aspartic-type endopeptidase activity - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - Asp_protease_2,TPR_19,gag-asp_proteas DYD1_k127_5416713_10 1144275.COCOR_02427 1.902e-09 68.0 COG0745@1|root,COG0745@2|Bacteria,1NQ8U@1224|Proteobacteria,42QWX@68525|delta/epsilon subdivisions,2WN80@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Domain of unknown function (DUF4388) - - - - - - - - - - - - DUF4388,Response_reg DYD1_k127_5416713_11 319795.Dgeo_1467 1.376e-08 65.0 COG2770@1|root,COG2770@2|Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - DUF3365,HAMP,dCache_1 DYD1_k127_5416713_9 1131814.JAFO01000001_gene1871 7.32e-14 81.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria 1224|Proteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2,TAT_signal DYD1_k127_5417773_1 313628.LNTAR_23674 3.284e-123 409.0 COG3344@1|root,COG3344@2|Bacteria 2|Bacteria L reverse transcriptase - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 DYD1_k127_5417773_2 177437.HRM2_20860 7.978e-86 298.0 COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,42Q95@68525|delta/epsilon subdivisions,2WKM2@28221|Deltaproteobacteria,2MIMV@213118|Desulfobacterales 28221|Deltaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase DYD1_k127_5417773_8 1223523.H340_01449 2.105e-13 83.0 COG4643@1|root,COG4643@2|Bacteria,2IAMR@201174|Actinobacteria 201174|Actinobacteria L Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987,DnaB DYD1_k127_5417773_11 135651.CBN25805 0.0007563 44.0 KOG4185@1|root,KOG4185@2759|Eukaryota,39F1H@33154|Opisthokonta,3CIYA@33208|Metazoa,3E0GU@33213|Bilateria,40MZX@6231|Nematoda,1M5F3@119089|Chromadorea,413P6@6236|Rhabditida 33208|Metazoa O Ring finger - - - - - - - - - - - - zf-RING_2,zf-RING_5 DYD1_k127_5417773_6 247490.KSU1_B0053 1.205e-27 118.0 28Y42@1|root,2ZJZI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5417773_4 298654.FraEuI1c_1773 7.002e-40 169.0 COG2319@1|root,COG2909@1|root,COG2319@2|Bacteria,COG2909@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales 201174|Actinobacteria P WD-40 repeat-containing protein - - - - - - - - - - - - DUF4062,NB-ARC,WD40 DYD1_k127_5417773_10 113395.AXAI01000038_gene121 3.997e-05 57.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 DYD1_k127_5417773_7 1454007.JAUG01000057_gene4507 2.017e-23 106.0 COG1059@1|root,COG1059@2|Bacteria 2|Bacteria L Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) ogg - 4.2.99.18 ko:K03653 - - - - ko00000,ko01000 - - - - DYD1_k127_5417773_5 335283.Neut_1369 4.516e-28 119.0 2BUEM@1|root,32PQM@2|Bacteria,1PY6C@1224|Proteobacteria,2VWI7@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5417773_3 1121937.AUHJ01000042_gene290 8.64e-74 258.0 COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,4679W@72275|Alteromonadaceae 1236|Gammaproteobacteria L PFAM IstB domain protein ATP-binding protein istB3 - - - - - - - - - - - IstB_IS21,IstB_IS21_ATP DYD1_k127_5417773_0 1167006.UWK_03323 5.919e-173 557.0 COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,42N2X@68525|delta/epsilon subdivisions,2X7GJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Sigma-70, region 4 - - - - - - - - - - - - rve DYD1_k127_5421186_1 309807.SRU_2769 1.038e-14 78.0 COG2128@1|root,COG2128@2|Bacteria,4NN22@976|Bacteroidetes,1FK4T@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S PA26 p53-induced protein (sestrin) - - - - - - - - - - - - CMD DYD1_k127_5421186_3 1042163.BRLA_c013330 7.675e-07 54.0 COG1765@1|root,COG1765@2|Bacteria,1V3B2@1239|Firmicutes,4HI09@91061|Bacilli,275RA@186822|Paenibacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC DYD1_k127_5421186_0 1437603.BMON_0422 1.807e-16 91.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_5421186_2 502025.Hoch_2631 2.588e-10 62.0 COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,42QCJ@68525|delta/epsilon subdivisions,2WKE7@28221|Deltaproteobacteria,2YUF8@29|Myxococcales 28221|Deltaproteobacteria G Glycosyl hydrolases family 15 - - - - - - - - - - - - DUF547,Glyco_hydro_15 DYD1_k127_5422044_0 443152.MDG893_15387 8.386e-139 466.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD1_k127_5422044_1 443152.MDG893_15467 2.854e-41 163.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_5497513_0 1173027.Mic7113_3738 0.0 1187.0 COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1G2UN@1117|Cyanobacteria,1H977@1150|Oscillatoriales 1117|Cyanobacteria G Alpha amylase, catalytic domain - - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - APH,Alpha-amylase,Malt_amylase_C DYD1_k127_5497513_4 1089553.Tph_c26440 8.727e-202 650.0 COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales 186801|Clostridia G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 DYD1_k127_5497513_2 479434.Sthe_1091 0.0 1009.0 COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia 189775|Thermomicrobia G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 DYD1_k127_5497513_7 671143.DAMO_2558 1.278e-142 468.0 COG0297@1|root,COG0297@2|Bacteria,2NP1F@2323|unclassified Bacteria 2|Bacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 DYD1_k127_5497513_5 671143.DAMO_0699 2.166e-191 604.0 COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria 2|Bacteria G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2768 NTP_transferase DYD1_k127_5497513_3 760568.Desku_2852 3.382e-238 751.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,261BK@186807|Peptococcaceae 186801|Clostridia G Domain of unknown function (DUF3459) - - 2.4.1.18,3.2.1.141 ko:K00700,ko:K01236 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110,R09995,R11256 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459 DYD1_k127_5497513_1 264732.Moth_1810 0.0 1039.0 COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,42HS1@68295|Thermoanaerobacterales 186801|Clostridia G Domain of unknown function (DUF3536) - - - - - - - - - - - - DUF3536,Glyco_hydro_57 DYD1_k127_5497513_6 1499967.BAYZ01000196_gene3073 1.586e-143 468.0 COG2379@1|root,COG2379@2|Bacteria,2NNQP@2323|unclassified Bacteria 2|Bacteria G MOFRL family ttuD - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL DYD1_k127_5497513_8 1123393.KB891331_gene2951 3.355e-31 126.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RKGT@1224|Proteobacteria,2W99B@28216|Betaproteobacteria,1KSUY@119069|Hydrogenophilales 119069|Hydrogenophilales M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl,OmpA DYD1_k127_5510982_1 402777.KB235903_gene1681 1.276e-281 878.0 COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales 1117|Cyanobacteria E PFAM Prolyl oligopeptidase family dap2 - - - - - - - - - - - PD40,Peptidase_S9 DYD1_k127_5510982_8 321327.CYA_1226 2.197e-24 108.0 COG1959@1|root,COG1959@2|Bacteria,1G5VI@1117|Cyanobacteria,1H1CY@1129|Synechococcus 1117|Cyanobacteria K Transcriptional regulator - - - - - - - - - - - - Rrf2 DYD1_k127_5510982_0 502025.Hoch_5119 4.328e-296 926.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales 28221|Deltaproteobacteria C Sulfite reductase - - 1.7.7.1,1.8.1.2,1.8.7.1 ko:K00366,ko:K00381,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00531 R00790,R00858,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr DYD1_k127_5510982_7 1128427.KB904821_gene3905 5.81e-27 117.0 2DUA0@1|root,33PJB@2|Bacteria,1GD0Q@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5510982_3 1459636.NTE_02662 1.114e-88 300.0 COG0175@1|root,arCOG00124@2157|Archaea,41S9Q@651137|Thaumarchaeota 651137|Thaumarchaeota E Phosphoadenosine phosphosulfate reductase family - - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct DYD1_k127_5510982_6 1009370.ALO_10609 5.047e-45 173.0 COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4H4P0@909932|Negativicutes 909932|Negativicutes H Siroheme synthase cysG - 1.3.1.76,4.99.1.4 ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947 RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M DYD1_k127_5510982_4 1121430.JMLG01000005_gene691 1.81e-88 300.0 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,2602S@186807|Peptococcaceae 186801|Clostridia H Belongs to the precorrin methyltransferase family cobA - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 ko:K02302,ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03165,R03194,R03947 RC00003,RC00871,RC01012,RC01034,RC01861 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS15755 HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase DYD1_k127_5510982_2 1288494.EBAPG3_21960 7.904e-158 503.0 COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2VJH9@28216|Betaproteobacteria,3725R@32003|Nitrosomonadales 28216|Betaproteobacteria H adenylyltransferase, small subunit cysD - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct DYD1_k127_5510982_5 1288494.EBAPG3_21980 9.751e-77 258.0 COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,371VC@32003|Nitrosomonadales 28216|Betaproteobacteria H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysN - 2.7.7.4 ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD1_k127_5553113_10 880072.Desac_1281 4.877e-12 66.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2MR0A@213462|Syntrophobacterales 28221|Deltaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2848 Pribosyl_synth,Pribosyltran_N DYD1_k127_5553113_3 667014.Thein_1532 1.811e-39 154.0 COG1825@1|root,COG1825@2|Bacteria,2GHKF@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C DYD1_k127_5553113_2 1449126.JQKL01000009_gene321 2.904e-50 184.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,2686B@186813|unclassified Clostridiales 186801|Clostridia J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro DYD1_k127_5553113_9 1121439.dsat_1334 4.703e-21 98.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2WRDG@28221|Deltaproteobacteria,2MCE6@213115|Desulfovibrionales 28221|Deltaproteobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 DYD1_k127_5553113_8 398767.Glov_2608 2.071e-25 108.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 DYD1_k127_5553113_7 335543.Sfum_3186 8.536e-30 130.0 COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,2MS2Q@213462|Syntrophobacterales 28221|Deltaproteobacteria S Predicted membrane protein (DUF2232) - - - - - - - - - - - - DUF2232 DYD1_k127_5553113_4 795359.TOPB45_0188 1.782e-37 147.0 COG0359@1|root,COG0359@2|Bacteria,2GHVJ@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N DYD1_k127_5553113_5 760192.Halhy_1163 3.555e-37 151.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - - - - - - - - - - EamA DYD1_k127_5553113_1 1459636.NTE_02180 5.784e-114 373.0 COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota 651137|Thaumarchaeota E DeoC/LacD family aldolase - - 2.3.1.245 ko:K08321 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - DeoC DYD1_k127_5553113_6 105559.Nwat_0046 7.491e-36 140.0 COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1X28T@135613|Chromatiales 135613|Chromatiales J 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_5553113_0 247490.KSU1_C0515 1.083e-140 454.0 COG1063@1|root,COG1063@2|Bacteria,2J2DX@203682|Planctomycetes 203682|Planctomycetes E Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD1_k127_5555843_1 1125863.JAFN01000001_gene577 5.647e-43 172.0 COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA DYD1_k127_5555843_0 1121396.KB893107_gene1840 7.421e-61 221.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WN9P@28221|Deltaproteobacteria,2MPHD@213118|Desulfobacterales 28221|Deltaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,Response_reg DYD1_k127_5559426_4 670487.Ocepr_0247 1.142e-06 56.0 COG1633@1|root,COG1633@2|Bacteria,1WK1G@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Rubrerythrin - - - - - - - - - - - - Rubrerythrin DYD1_k127_5559426_0 1123368.AUIS01000038_gene37 8.977e-86 288.0 COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,1S4YT@1236|Gammaproteobacteria,2ND78@225057|Acidithiobacillales 225057|Acidithiobacillales S Dienelactone hydrolase family - - - - - - - - - - - - DLH DYD1_k127_5559426_2 1089553.Tph_c00500 8.229e-38 149.0 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,24I2P@186801|Clostridia,42GMX@68295|Thermoanaerobacterales 186801|Clostridia S Domain in cystathionine beta-synthase and other proteins. acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS DYD1_k127_5559426_1 269799.Gmet_0421 5.036e-82 278.0 COG2823@1|root,COG2823@2|Bacteria,1RFX5@1224|Proteobacteria,42UUG@68525|delta/epsilon subdivisions,2WQ1N@28221|Deltaproteobacteria,43U92@69541|Desulfuromonadales 28221|Deltaproteobacteria S BON domain - - - - - - - - - - - - BON DYD1_k127_5565327_5 485913.Krac_8525 0.0002773 49.0 COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria 2|Bacteria C response to copper ion - - - ko:K07156,ko:K14166 - - - - ko00000,ko02000 9.B.62.2 - - CopC,CopD,YtkA DYD1_k127_5565327_4 1223410.KN050846_gene545 1.575e-16 89.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia 976|Bacteroidetes M Belongs to the ompA family yiaD - - - - - - - - - - - Gly-zipper_Omp,OmpA DYD1_k127_5565327_0 1123376.AUIU01000016_gene233 2.38e-198 628.0 COG2204@1|root,COG2204@2|Bacteria,3J0ZU@40117|Nitrospirae 40117|Nitrospirae T Bacterial regulatory protein, Fis family - - - ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5565327_3 909663.KI867150_gene876 8.737e-23 107.0 COG1196@1|root,COG1196@2|Bacteria,1NQEI@1224|Proteobacteria,42XZI@68525|delta/epsilon subdivisions,2WTDN@28221|Deltaproteobacteria,2MSDB@213462|Syntrophobacterales 28221|Deltaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - DYD1_k127_5565327_1 1123376.AUIU01000016_gene231 1.312e-142 467.0 COG5002@1|root,COG5002@2|Bacteria,3J10G@40117|Nitrospirae 40117|Nitrospirae T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_5565327_2 1210884.HG799466_gene12833 2.804e-36 139.0 COG2957@1|root,COG2957@2|Bacteria,2IXRY@203682|Planctomycetes 203682|Planctomycetes E Belongs to the agmatine deiminase family aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph DYD1_k127_5566330_4 1509405.GV67_12630 3.529e-05 49.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5566330_3 487521.OCU_15350 2.245e-14 83.0 COG0346@1|root,COG0346@2|Bacteria,2GW68@201174|Actinobacteria,23D7F@1762|Mycobacteriaceae 201174|Actinobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase DYD1_k127_5566330_2 622637.KE124774_gene3774 1.482e-31 129.0 COG5606@1|root,COG5606@2|Bacteria,1NE1Y@1224|Proteobacteria,2UG3C@28211|Alphaproteobacteria,36Z13@31993|Methylocystaceae 28211|Alphaproteobacteria S Helix-turn-helix domain - - - - - - - - - - - - HTH_37 DYD1_k127_5566330_1 398767.Glov_1131 6.684e-38 145.0 COG4679@1|root,COG4679@2|Bacteria,1MZC9@1224|Proteobacteria,42VAA@68525|delta/epsilon subdivisions,2WS9T@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 DYD1_k127_5566330_0 103733.JNYO01000007_gene5113 6.954e-89 303.0 COG0059@1|root,COG0059@2|Bacteria,2IK1H@201174|Actinobacteria,4EBDV@85010|Pseudonocardiales 201174|Actinobacteria EH S-adenosyl-L-homocysteine hydrolase, NAD binding domain - - - - - - - - - - - - IlvC,IlvN DYD1_k127_5567458_10 1500894.JQNN01000001_gene3738 4.787e-69 247.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,473D4@75682|Oxalobacteraceae 28216|Betaproteobacteria M Glycosyl transferases group 1 - - - ko:K00786 - - - - ko00000,ko01000 - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 DYD1_k127_5567458_7 323848.Nmul_A2523 1.729e-93 319.0 COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2VNEW@28216|Betaproteobacteria,3729A@32003|Nitrosomonadales 28216|Betaproteobacteria V FemAB family - - - - - - - - - - - - Acetyltransf_6 DYD1_k127_5567458_3 880073.Calab_0614 6.963e-125 413.0 COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria 2|Bacteria M UDP-N-acetylglucosamine 2-epimerase wecB - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 DYD1_k127_5567458_6 404380.Gbem_1774 2.964e-97 325.0 COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,42P7W@68525|delta/epsilon subdivisions,2WMHU@28221|Deltaproteobacteria 28221|Deltaproteobacteria G TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - - - - - - - - - - DUF3473,Polysacc_deac_1 DYD1_k127_5567458_5 1125863.JAFN01000001_gene473 2.063e-100 343.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 DYD1_k127_5567458_14 880072.Desac_2192 4.207e-35 146.0 COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,42QS3@68525|delta/epsilon subdivisions,2WMX0@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Capsular exopolysaccharide family - - - - - - - - - - - - AAA_31,CbiA DYD1_k127_5567458_9 857087.Metme_1377 5.406e-70 253.0 COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1XERT@135618|Methylococcales 135618|Methylococcales U SMART ATPase, AAA type, core - - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 DYD1_k127_5567458_8 1125863.JAFN01000001_gene622 4.027e-82 292.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,42M2D@68525|delta/epsilon subdivisions,2WJU6@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Lipopolysaccharide biosynthesis protein wzc1 - - - - - - - - - - - GNVR,Wzz DYD1_k127_5567458_13 1382359.JIAL01000001_gene945 2.147e-37 150.0 COG1596@1|root,COG1596@2|Bacteria,3Y51C@57723|Acidobacteria,2JJMM@204432|Acidobacteriia 204432|Acidobacteriia M Polysaccharide biosynthesis/export protein - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB DYD1_k127_5567458_1 237368.SCABRO_02014 7.957e-136 447.0 COG2204@1|root,COG2204@2|Bacteria,2IYIG@203682|Planctomycetes 203682|Planctomycetes T CheY-like receiver AAA-type ATPase and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5567458_15 880072.Desac_0716 1.07e-14 86.0 COG4191@1|root,COG4191@2|Bacteria,1RI33@1224|Proteobacteria,42SUG@68525|delta/epsilon subdivisions,2WP3A@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase bamV - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1 DYD1_k127_5567458_11 272844.PAB0888 8.793e-51 201.0 COG0028@1|root,arCOG01998@2157|Archaea,2XT5F@28890|Euryarchaeota,243I4@183968|Thermococci 183968|Thermococci E Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_5567458_12 203122.Sde_0750 3.018e-38 164.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,4643T@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG0642 Signal transduction histidine kinase prsK - - - - - - - - - - - GAF_2,HATPase_c DYD1_k127_5567458_2 1121918.ARWE01000001_gene1791 4.584e-127 424.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Q6R@68525|delta/epsilon subdivisions,2WJN4@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Sigma-54 factor interaction domain-containing protein - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5567458_0 1379698.RBG1_1C00001G0637 3.932e-173 555.0 COG0677@1|root,COG0677@2|Bacteria,2NNQ1@2323|unclassified Bacteria 2|Bacteria M UDP binding domain - - 1.1.1.136 ko:K02474,ko:K13015 ko00520,map00520 - R00421,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_5567458_4 1232410.KI421413_gene935 3.987e-106 356.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,43TJH@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ DYD1_k127_5570487_0 497964.CfE428DRAFT_2340 1.076e-159 518.0 COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia 74201|Verrucomicrobia J GTP binding - - - - - - - - - - - - - DYD1_k127_5570487_2 1535287.JP74_06510 1.57e-80 278.0 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2TV8R@28211|Alphaproteobacteria,3N8F9@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family pmtA - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 DYD1_k127_5570487_8 671143.DAMO_1580 2.872e-26 109.0 COG2442@1|root,COG2442@2|Bacteria 2|Bacteria K InterPro IPR007367 - - - - - - - - - - - - DUF433 DYD1_k127_5570487_15 1280692.AUJL01000001_gene300 0.0002896 45.0 COG3677@1|root,COG3677@2|Bacteria,1UYY4@1239|Firmicutes,248FF@186801|Clostridia,36MGH@31979|Clostridiaceae 186801|Clostridia L Psort location Cytoplasmic, score - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1,Zn_Tnp_IS1595 DYD1_k127_5570487_9 1070319.CAGGBEG34_410005 5.438e-26 111.0 COG1662@1|root,COG1662@2|Bacteria,1RIVU@1224|Proteobacteria 1224|Proteobacteria L cog cog1662 insB - - ko:K07480 - - - - ko00000 - - - DDE_Tnp_IS1 DYD1_k127_5570487_1 1333507.AUTQ01000230_gene2323 1.427e-88 295.0 COG2095@1|root,COG2095@2|Bacteria,1MV1C@1224|Proteobacteria,1RPM8@1236|Gammaproteobacteria,2Q22Q@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria U MarC family integral membrane protein marC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD1_k127_5570487_12 196367.JNFG01000007_gene6763 5.816e-14 78.0 2DNM2@1|root,32Y26@2|Bacteria,1N7KR@1224|Proteobacteria,2WFQB@28216|Betaproteobacteria,1KI4S@119060|Burkholderiaceae 28216|Betaproteobacteria S Lipocalin-like domain - - - - - - - - - - - - Lipocalin_5 DYD1_k127_5570487_5 1114970.PSF113_3457 2.874e-40 159.0 COG3473@1|root,COG3473@2|Bacteria,1RC29@1224|Proteobacteria,1SJEY@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG3473 Maleate cis-trans isomerase - - - - - - - - - - - - - DYD1_k127_5570487_4 216594.MMAR_2798 2.498e-52 201.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_5570487_6 1163617.SCD_n02362 2.116e-34 138.0 29V5H@1|root,30GJ5@2|Bacteria,1PHC8@1224|Proteobacteria,2VRT9@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3617) - - - - - - - - - - - - DUF3617 DYD1_k127_5570487_7 257310.BB0718 3.056e-30 126.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VZBQ@28216|Betaproteobacteria 28216|Betaproteobacteria G Phosphoenolpyruvate phosphomutase - - 4.1.3.32 ko:K20454 ko00760,ko01120,map00760,map01120 - R01355 RC00286,RC01810 ko00000,ko00001,ko01000 - - - PEP_mutase DYD1_k127_5570487_10 1500259.JQLD01000010_gene4824 1.617e-24 116.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5570487_3 1231391.AMZF01000046_gene961 1.088e-52 199.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_5570487_11 1089545.KB913037_gene1905 2.277e-23 112.0 COG2309@1|root,COG2309@2|Bacteria 2|Bacteria E aminopeptidase activity - - - - - - - - - - - - - DYD1_k127_5570487_13 1157708.KB907476_gene1095 1.369e-12 80.0 COG0715@1|root,COG0715@2|Bacteria,1MWC5@1224|Proteobacteria,2W625@28216|Betaproteobacteria 28216|Betaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_5570487_14 1122915.AUGY01000020_gene6479 2.28e-09 68.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_558576_10 1321778.HMPREF1982_04172 5.527e-13 68.0 2DR3E@1|root,33A02@2|Bacteria,1VKEX@1239|Firmicutes,24UH8@186801|Clostridia,26CD0@186813|unclassified Clostridiales 186801|Clostridia S Glycine reductase complex selenoprotein A grdA - 1.21.4.2,1.21.4.3,1.21.4.4 ko:K10670 - - - - ko00000,ko01000 - - - GRDA DYD1_k127_558576_8 525903.Taci_1137 4.081e-27 113.0 2AE14@1|root,313TT@2|Bacteria,3TB4Q@508458|Synergistetes 508458|Synergistetes S PFAM glycine reductase complex selenoprotein A - - 1.21.4.2,1.21.4.3,1.21.4.4 ko:K10670 - - - - ko00000,ko01000 - - - GRDA DYD1_k127_558576_11 1320556.AVBP01000022_gene2055 1.212e-08 66.0 COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2TSHF@28211|Alphaproteobacteria,43H6C@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_558576_4 56780.SYN_02775 3.432e-52 192.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,43EVS@68525|delta/epsilon subdivisions,2X9S4@28221|Deltaproteobacteria,2MSFB@213462|Syntrophobacterales 28221|Deltaproteobacteria S HAD-hyrolase-like - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 DYD1_k127_558576_6 1187851.A33M_3396 6.765e-39 150.0 COG3467@1|root,COG3467@2|Bacteria 2|Bacteria T pyridoxamine 5'-phosphate - - - ko:K07005 - - - - ko00000 - - - Putative_PNPOx,Pyridox_ox_2 DYD1_k127_558576_5 485914.Hmuk_2787 2.831e-45 176.0 COG2423@1|root,arCOG01035@2157|Archaea,2XT4P@28890|Euryarchaeota,23TF8@183963|Halobacteria 183963|Halobacteria E ornithine cyclodeaminase mu-crystallin ocd2 - 1.4.1.1 ko:K19244 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_558576_3 1121448.DGI_2105 3.196e-54 203.0 COG0765@1|root,COG0765@2|Bacteria,1PT12@1224|Proteobacteria,431XJ@68525|delta/epsilon subdivisions,2X5TF@28221|Deltaproteobacteria,2MGVN@213115|Desulfovibrionales 28221|Deltaproteobacteria P amino acid ABC transporter - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 DYD1_k127_558576_1 1038867.AXAY01000057_gene320 1.099e-60 218.0 COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2TRAT@28211|Alphaproteobacteria,3JVGT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Binding-protein-dependent transport system inner membrane component - - - ko:K10003 ko02010,ko02020,map02010,map02020 M00230 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.19,3.A.1.3.4 - - BPD_transp_1 DYD1_k127_558576_2 644968.DFW101_2306 5.561e-55 206.0 COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,43AV1@68525|delta/epsilon subdivisions,2X5J3@28221|Deltaproteobacteria,2MGRR@213115|Desulfovibrionales 28221|Deltaproteobacteria ET PFAM Extracellular solute-binding protein, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD1_k127_558576_0 485915.Dret_2028 8.352e-106 351.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2M7ZW@213115|Desulfovibrionales 28221|Deltaproteobacteria E PFAM ABC transporter related - - 3.6.3.21 ko:K02028,ko:K10038 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.2 - - ABC_tran DYD1_k127_558576_7 671143.DAMO_0142 2.494e-28 120.0 COG2062@1|root,COG2062@2|Bacteria,2NRKX@2323|unclassified Bacteria 2|Bacteria T Histidine phosphatase superfamily (branch 1) sixA - 3.6.1.55 ko:K03574,ko:K08296 - - - - ko00000,ko01000,ko03400 - - - His_Phos_1 DYD1_k127_558576_9 326427.Cagg_3738 1.062e-24 104.0 COG0372@1|root,COG0372@2|Bacteria,2G637@200795|Chloroflexi,3765M@32061|Chloroflexia 32061|Chloroflexia H Belongs to the citrate synthase family - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD1_k127_5589912_3 1120972.AUMH01000006_gene1898 2.764e-88 302.0 COG4638@1|root,COG4638@2|Bacteria 2|Bacteria P Rieske (2fe-2S) ligX - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_5589912_0 1120972.AUMH01000002_gene2761 1.795e-108 363.0 2C1EV@1|root,33RW1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Cupin_2 DYD1_k127_5589912_1 1120949.KB903314_gene302 2.144e-106 366.0 COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria 201174|Actinobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 DYD1_k127_5589912_2 1120949.KB903314_gene301 6.032e-94 324.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria 201174|Actinobacteria E Belongs to the ABC transporter superfamily potA - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 DYD1_k127_5589912_4 479434.Sthe_2790 1.838e-77 275.0 COG0477@1|root,COG0477@2|Bacteria,2G5YG@200795|Chloroflexi,27XKV@189775|Thermomicrobia 189775|Thermomicrobia EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 DYD1_k127_5589912_5 1120983.KB894571_gene2128 1.306e-45 176.0 COG3384@1|root,COG3384@2|Bacteria,1R3TY@1224|Proteobacteria,2VGIR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB DYD1_k127_5589912_6 1293048.CBMB010000004_gene2312 8.171e-39 158.0 arCOG08113@1|root,arCOG08113@2157|Archaea,2XV1B@28890|Euryarchaeota,23TAX@183963|Halobacteria 183963|Halobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - BNR DYD1_k127_5590249_9 439235.Dalk_2782 1.462e-81 297.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2MI3T@213118|Desulfobacterales 28221|Deltaproteobacteria S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B DYD1_k127_5590249_1 1125863.JAFN01000001_gene1129 2.109e-176 572.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria 28221|Deltaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N DYD1_k127_5590249_0 1125863.JAFN01000001_gene674 5.786e-298 929.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria 28221|Deltaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB DYD1_k127_5590249_22 2850.Phatr44566 2.327e-10 69.0 2CZGI@1|root,2SAAG@2759|Eukaryota,2XDN7@2836|Bacillariophyta 2836|Bacillariophyta S Putative zinc- or iron-chelating domain - - - - - - - - - - - - CxxCxxCC DYD1_k127_5590249_13 1283283.ATXA01000006_gene1854 5.813e-71 252.0 COG3435@1|root,COG3435@2|Bacteria,2GZST@201174|Actinobacteria 201174|Actinobacteria Q Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_5590249_4 1278073.MYSTI_02643 1.13e-147 482.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria,2YUQE@29|Myxococcales 28221|Deltaproteobacteria E Peptidase dimerisation domain - - - ko:K13049 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD1_k127_5590249_2 99598.Cal7507_5457 1.736e-158 515.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1HJFJ@1161|Nostocales 1117|Cyanobacteria M Substrate binding domain of ABC-type glycine betaine transport system - - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC DYD1_k127_5590249_6 1173026.Glo7428_2778 1.388e-98 327.0 COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria 1117|Cyanobacteria E 'ABC-type proline glycine betaine transport - - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS DYD1_k127_5590249_16 91464.S7335_2389 8.254e-62 226.0 COG4301@1|root,COG4301@2|Bacteria,1G2JI@1117|Cyanobacteria,1GZUA@1129|Synechococcus 1117|Cyanobacteria S Histidine-specific methyltransferase, SAM-dependent - - - - - - - - - - - - Methyltransf_33 DYD1_k127_5590249_14 1206735.BAGG01000110_gene4710 5.05e-66 236.0 COG3239@1|root,COG3239@2|Bacteria,2I8NB@201174|Actinobacteria,4G0AE@85025|Nocardiaceae 201174|Actinobacteria I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase DYD1_k127_5590249_19 388467.A19Y_2283 6.937e-55 205.0 COG1280@1|root,COG1280@2|Bacteria,1G59K@1117|Cyanobacteria,1HAV4@1150|Oscillatoriales 1117|Cyanobacteria E LysE type translocator - - - - - - - - - - - - LysE DYD1_k127_5590249_18 391595.RLO149_c008070 1.808e-56 207.0 COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,2TRJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Formylglycine-generating sulfatase enzyme - - 1.14.99.50 ko:K18912,ko:K20333 ko00340,ko02024,map00340,map02024 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - FGE-sulfatase DYD1_k127_5590249_17 525904.Tter_0116 5.746e-59 218.0 COG3525@1|root,COG3525@2|Bacteria,2NPTI@2323|unclassified Bacteria 2|Bacteria G beta-N-acetylglucosaminidase hyl GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 2.3.1.48,3.2.1.169,3.2.1.35 ko:K01197,ko:K15719 ko00531,ko01100,ko04931,map00531,map01100,map04931 M00076,M00077 R07824,R07825,R09672,R09673,R10905 RC00059,RC00397,RC00451,RC00746 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 - GH84 - F5_F8_type_C,Glyco_hydro_20b,NAGidase DYD1_k127_5590249_3 404589.Anae109_0564 2.8e-155 503.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria 1224|Proteobacteria H Methyl-transferase egtB - 1.14.99.50 ko:K18912 ko00340,map00340 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - DinB_2,FGE-sulfatase DYD1_k127_5590249_8 1163617.SCD_n01615 1.446e-86 298.0 COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria 28216|Betaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 DYD1_k127_5590249_7 706587.Desti_4883 1.575e-88 307.0 COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,42YIF@68525|delta/epsilon subdivisions,2WU4S@28221|Deltaproteobacteria,2MQET@213462|Syntrophobacterales 28221|Deltaproteobacteria EGP PFAM Major Facilitator Superfamily - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 DYD1_k127_5590249_24 1132509.C447_06501 2.558e-06 56.0 COG0589@1|root,arCOG02053@2157|Archaea,2XX8Y@28890|Euryarchaeota,23VQJ@183963|Halobacteria 183963|Halobacteria T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp DYD1_k127_5590249_5 330214.NIDE3611 1.43e-108 364.0 COG1723@1|root,COG1723@2|Bacteria 2|Bacteria S PFAM Uncharacterised ACR, YagE family COG1723 yagE - - - - - - - - - - - DUF155 DYD1_k127_5590249_12 1382359.JIAL01000001_gene2527 5.035e-73 256.0 COG1945@1|root,COG1945@2|Bacteria,3Y3KR@57723|Acidobacteria,2JIBD@204432|Acidobacteriia 204432|Acidobacteriia S Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) - - 4.1.1.19 ko:K02626 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PvlArgDC DYD1_k127_5590249_10 215803.DB30_5661 5.395e-81 289.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales 28221|Deltaproteobacteria FP Ppx/GppA phosphatase family gppA-2 - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA DYD1_k127_5590249_21 519989.ECTPHS_07112 1.097e-21 100.0 COG0394@1|root,COG0394@2|Bacteria,1RHA3@1224|Proteobacteria,1S676@1236|Gammaproteobacteria,1X2GD@135613|Chromatiales 135613|Chromatiales T Low molecular weight phosphotyrosine protein phosphatase - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc DYD1_k127_5590249_20 388467.A19Y_1916 2.349e-27 117.0 COG2062@1|root,COG2062@2|Bacteria,1G6QD@1117|Cyanobacteria,1HBRK@1150|Oscillatoriales 1117|Cyanobacteria T Phosphohistidine phosphatase, SixA sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 DYD1_k127_5590249_23 323259.Mhun_2988 3.938e-08 64.0 COG0639@1|root,COG5607@1|root,arCOG01143@2157|Archaea,arCOG05139@2157|Archaea,2XUDG@28890|Euryarchaeota,2NAJW@224756|Methanomicrobia 224756|Methanomicrobia T Calcineurin-like phosphoesterase superfamily domain - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - CHAD,Metallophos_2 DYD1_k127_5590249_11 485913.Krac_9227 6.097e-80 274.0 COG0125@1|root,COG0125@2|Bacteria 2|Bacteria F dTDP biosynthetic process tmk GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 ko:K00943,ko:K01585 ko00240,ko00330,ko01100,map00240,map00330,map01100 M00053,M00133 R00566,R02094,R02098 RC00002,RC00299 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c AAA_33,Thymidylate_kin DYD1_k127_5590249_15 485913.Krac_9228 2.253e-64 224.0 COG0125@1|root,COG0125@2|Bacteria 2|Bacteria F dTDP biosynthetic process tmk GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 ko:K00560,ko:K00943,ko:K01585 ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523 M00053,M00133 R00566,R02094,R02098,R02101 RC00002,RC00219,RC00299,RC00332 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c AAA_33,Thymidylate_kin DYD1_k127_5603084_2 1298867.AUES01000085_gene3659 2.16e-16 83.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5603084_3 113395.AXAI01000004_gene4176 1.451e-08 57.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5603084_4 179408.Osc7112_6917 2.329e-05 52.0 2DW4I@1|root,32V0S@2|Bacteria,1G7NI@1117|Cyanobacteria,1HFI4@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5603084_1 189753.AXAS01000041_gene2534 3.778e-70 252.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5603084_5 391623.TERMP_01724 9.57e-05 46.0 arCOG00818@1|root,arCOG00818@2157|Archaea,2XZC0@28890|Euryarchaeota,244RZ@183968|Thermococci 183968|Thermococci K Antidote-toxin recognition MazE, bacterial antitoxin - - - - - - - - - - - - MazE_antitoxin DYD1_k127_5603084_0 439235.Dalk_1526 1.589e-206 684.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales 28221|Deltaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12 DYD1_k127_5605751_7 443152.MDG893_15060 2.072e-05 49.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_5605751_5 443152.MDG893_15467 2.103e-54 203.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_5605751_0 1337936.IJ00_25065 1.937e-220 692.0 COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,1HMNK@1161|Nostocales 1117|Cyanobacteria C Belongs to the aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 ko:K00128,ko:K00135,ko:K22187 ko00010,ko00040,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD1_k127_5605751_1 909663.KI867150_gene247 1.36e-157 509.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales 28221|Deltaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_5605751_6 671143.DAMO_2130 2.167e-47 177.0 COG3063@1|root,COG3063@2|Bacteria 2|Bacteria NU photosynthesis sscB - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8 DYD1_k127_5605751_2 330214.NIDE3580 1.06e-97 324.0 COG1028@1|root,COG1028@2|Bacteria 330214.NIDE3580|- IQ oxidoreductase activity, acting on CH-OH group of donors - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - - DYD1_k127_5605751_4 469383.Cwoe_5826 3.383e-73 254.0 COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria 84995|Rubrobacteria S PAC2 family - - - - - - - - - - - - PAC2 DYD1_k127_5605751_3 671143.DAMO_1459 4.884e-96 319.0 COG1215@1|root,COG1215@2|Bacteria,2NPIY@2323|unclassified Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_5607316_3 350058.Mvan_0472 2.837e-60 220.0 COG0329@1|root,COG0329@2|Bacteria,2HN4J@201174|Actinobacteria,23EW4@1762|Mycobacteriaceae 201174|Actinobacteria EM PFAM Dihydrodipicolinate synthetase - - 4.1.2.34 ko:K11946,ko:K11949 ko00624,ko01100,ko01120,ko01220,map00624,map01100,map01120,map01220 - R05648,R07713 RC00924,RC00936 ko00000,ko00001,ko01000 - - - DHDPS DYD1_k127_5607316_4 90813.JQMT01000001_gene1704 9.051e-46 171.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1SCRQ@1236|Gammaproteobacteria,462VA@72273|Thiotrichales 72273|Thiotrichales K ECF sigma factor - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_5607316_5 391038.Bphy_4088 4.577e-05 51.0 COG5612@1|root,COG5612@2|Bacteria,1N8FF@1224|Proteobacteria,2VXB2@28216|Betaproteobacteria,1K78N@119060|Burkholderiaceae 28216|Betaproteobacteria S Heavy-metal resistance - - - - - - - - - - - - Metal_resist DYD1_k127_5607316_1 686340.Metal_1823 1.053e-107 362.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,1XEP7@135618|Methylococcales 135618|Methylococcales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_D23 DYD1_k127_5607316_0 856793.MICA_416 1.009e-256 809.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,4BQ2M@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria V ATPases associated with a variety of cellular activities macB - - ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - ABC_tran,FtsX,MacB_PCD DYD1_k127_5607316_2 856793.MICA_417 2.371e-99 340.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,4BQEN@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria MU Outer membrane efflux protein MA20_30040 - - - - - - - - - - - OEP DYD1_k127_5608794_1 333138.LQ50_20165 1.071e-89 308.0 2A6Y1@1|root,30VSZ@2|Bacteria,1UBKQ@1239|Firmicutes,4IN0U@91061|Bacilli,1ZMG5@1386|Bacillus 91061|Bacilli G Cupin domain - - - - - - - - - - - - Cupin_2 DYD1_k127_5608794_8 768670.Calni_0149 1.505e-11 69.0 COG4968@1|root,COG4968@2|Bacteria,2GGQE@200930|Deferribacteres 200930|Deferribacteres NU Prokaryotic N-terminal methylation motif - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl DYD1_k127_5608794_6 273068.TTE0051 6.114e-48 182.0 COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,42EQW@68295|Thermoanaerobacterales 186801|Clostridia IQ PFAM Short-chain dehydrogenase reductase SDR fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 DYD1_k127_5608794_7 1121396.KB893112_gene1999 3.063e-34 135.0 COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,42VMT@68525|delta/epsilon subdivisions,2WPFB@28221|Deltaproteobacteria,2MK8N@213118|Desulfobacterales 28221|Deltaproteobacteria S FxsA cytoplasmic membrane protein fsxA - - ko:K07113 - - - - ko00000 - - - FxsA DYD1_k127_5608794_2 324602.Caur_3129 1.139e-86 295.0 COG0614@1|root,COG0614@2|Bacteria,2G6EF@200795|Chloroflexi,376B5@32061|Chloroflexia 32061|Chloroflexia P PFAM periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 DYD1_k127_5608794_5 485913.Krac_7973 2.397e-62 222.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_5608794_3 771875.Ferpe_0714 1.871e-69 258.0 COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae 200918|Thermotogae F PFAM PQQ enzyme repeat - - - - - - - - - - - - PQQ_3 DYD1_k127_5608794_0 237368.SCABRO_01831 2.634e-139 459.0 COG1215@1|root,COG1215@2|Bacteria,2IXX6@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferase family group 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2,PilZ DYD1_k127_5608794_4 671143.DAMO_0611 4.811e-66 241.0 COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria 2|Bacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - GT87 DYD1_k127_5610845_2 1110502.TMO_0012 5.3e-50 190.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_5610845_3 1123257.AUFV01000003_gene841 6.492e-46 169.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA DYD1_k127_5610845_5 671143.DAMO_2196 7.814e-05 47.0 2E90H@1|root,3339X@2|Bacteria,2NS0Z@2323|unclassified Bacteria 2|Bacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - DYD1_k127_5610845_1 1121396.KB893058_gene2565 4.545e-63 226.0 COG0657@1|root,COG0657@2|Bacteria 2|Bacteria I acetylesterase activity - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3,Peptidase_S9 DYD1_k127_5610845_4 1828.JOKB01000058_gene803 1.274e-08 66.0 COG0715@1|root,COG0715@2|Bacteria,2ID1Q@201174|Actinobacteria,4FY89@85025|Nocardiaceae 201174|Actinobacteria P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_5610845_0 1173027.Mic7113_2967 9.626e-99 334.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 2|Bacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5617571_8 485913.Krac_9228 7.056e-53 188.0 COG0125@1|root,COG0125@2|Bacteria 2|Bacteria F dTDP biosynthetic process tmk GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 ko:K00560,ko:K00943,ko:K01585 ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523 M00053,M00133 R00566,R02094,R02098,R02101 RC00002,RC00219,RC00299,RC00332 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c AAA_33,Thymidylate_kin DYD1_k127_5617571_0 251221.35210568 1.552e-157 502.0 COG0226@1|root,COG0226@2|Bacteria,1FZZ0@1117|Cyanobacteria 1117|Cyanobacteria P TIGRFAM phosphate binding protein sphX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like,PBP_like_2 DYD1_k127_5617571_2 251221.35210569 4.119e-132 430.0 COG0573@1|root,COG0573@2|Bacteria,1G1JR@1117|Cyanobacteria 1117|Cyanobacteria P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 DYD1_k127_5617571_1 1173024.KI912151_gene2218 2.744e-138 454.0 COG0581@1|root,COG0581@2|Bacteria,1G2GA@1117|Cyanobacteria,1JHYX@1189|Stigonemataceae 1117|Cyanobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 DYD1_k127_5617571_3 1286106.MPL1_06769 1.075e-116 383.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,46073@72273|Thiotrichales 72273|Thiotrichales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran DYD1_k127_5617571_5 330214.NIDE2416 1.891e-78 268.0 COG0704@1|root,COG0704@2|Bacteria,3J0M6@40117|Nitrospirae 40117|Nitrospirae P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU DYD1_k127_5617571_6 1111479.AXAR01000012_gene1373 3.577e-73 255.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,279HQ@186823|Alicyclobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD1_k127_5617571_4 671143.DAMO_1128 7.24e-92 325.0 COG5002@1|root,COG5002@2|Bacteria,2NNKK@2323|unclassified Bacteria 2|Bacteria T His Kinase A (phosphoacceptor) domain phoR - 2.7.13.3 ko:K02484,ko:K07636,ko:K07768 ko02020,map02020 M00434,M00443 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like DYD1_k127_5617571_7 1293054.HSACCH_01737 6.773e-72 248.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3WB9U@53433|Halanaerobiales 186801|Clostridia L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 DYD1_k127_5617571_9 335541.Swol_0031 1.375e-10 61.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,42K27@68298|Syntrophomonadaceae 186801|Clostridia L Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd DYD1_k127_5619871_0 671143.DAMO_3030 5.058e-135 439.0 COG1804@1|root,COG1804@2|Bacteria,2NQGI@2323|unclassified Bacteria 2|Bacteria C CoA-transferase family III caiB GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 DYD1_k127_5619871_2 1121924.ATWH01000016_gene3076 1.172e-07 58.0 COG0599@1|root,COG0599@2|Bacteria,2H262@201174|Actinobacteria 201174|Actinobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD1_k127_5619871_1 1382304.JNIL01000001_gene2406 4.219e-97 338.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli 91061|Bacilli EH Acetolactate synthase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_5634113_1 690585.JNNU01000009_gene527 2.151e-28 128.0 COG1840@1|root,COG1840@2|Bacteria,1PGNI@1224|Proteobacteria,2V7J9@28211|Alphaproteobacteria,4B9P8@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11 DYD1_k127_5634113_0 189753.AXAS01000041_gene2534 6.633e-70 245.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5634113_2 224911.27353474 5.909e-07 54.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5638017_4 339671.Asuc_1210 3.739e-26 116.0 COG0417@1|root,COG0417@2|Bacteria,1QVMG@1224|Proteobacteria,1T2EP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Predicted 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 DYD1_k127_5638017_0 330214.NIDE2086 4.729e-253 820.0 COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae 40117|Nitrospirae L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C DYD1_k127_5638017_1 330214.NIDE2085 4.655e-169 572.0 COG3857@1|root,COG3857@2|Bacteria 2|Bacteria L exonuclease activity addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C DYD1_k127_5638017_2 758.BBIX01000006_gene468 1.868e-139 462.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1Y9NE@135625|Pasteurellales 135625|Pasteurellales M Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD1_k127_5638017_5 1123392.AQWL01000007_gene1017 3.509e-15 83.0 COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria,1KRW7@119069|Hydrogenophilales 119069|Hydrogenophilales S Putative Actinobacterial Holin-X, holin superfamily III - - - - - - - - - - - - Phage_holin_3_6 DYD1_k127_5638017_3 395494.Galf_2212 1.047e-28 117.0 COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,44WIE@713636|Nitrosomonadales 28216|Betaproteobacteria S Bacterial protein of unknown function (DUF883) - - - - - - - - - - - - DUF883 DYD1_k127_5640699_24 4920.XP_004204298.1 3.494e-07 61.0 COG5036@1|root,COG5264@1|root,KOG1161@2759|Eukaryota,KOG4580@2759|Eukaryota,38D0A@33154|Opisthokonta,3NU6V@4751|Fungi,3QJDY@4890|Ascomycota,3RSBP@4891|Saccharomycetes,47BG3@766764|Debaryomycetaceae 4751|Fungi OPU VTC domain VTC4 GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0000822,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0006082,GO:0006793,GO:0006796,GO:0006797,GO:0006799,GO:0006810,GO:0006914,GO:0006996,GO:0007033,GO:0007034,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009056,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016237,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019932,GO:0023052,GO:0031090,GO:0031224,GO:0031300,GO:0031310,GO:0032991,GO:0033254,GO:0035556,GO:0036094,GO:0042144,GO:0043167,GO:0043168,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0048016,GO:0048284,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0061024,GO:0061025,GO:0061919,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0097576,GO:0098588,GO:0098805,GO:0098852,GO:0101031,GO:1901576 - - - - - - - - - - DUF202,SPX,VTC DYD1_k127_5640699_22 998674.ATTE01000001_gene1948 1.678e-16 92.0 COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,4607Y@72273|Thiotrichales 72273|Thiotrichales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_5640699_18 118168.MC7420_6291 1.22e-47 183.0 COG3221@1|root,COG3221@2|Bacteria,1G2AZ@1117|Cyanobacteria,1HAC9@1150|Oscillatoriales 1117|Cyanobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd DYD1_k127_5640699_13 330214.NIDE0964 1.793e-61 231.0 COG0642@1|root,COG2205@2|Bacteria 330214.NIDE0964|- T PhoQ Sensor - - - - - - - - - - - - - DYD1_k127_5640699_20 243231.GSU1129 7.54e-21 108.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UD9@69541|Desulfuromonadales 28221|Deltaproteobacteria T response regulator - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5640699_23 477974.Daud_0675 5.594e-13 82.0 COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,25F8J@186801|Clostridia,2673W@186807|Peptococcaceae 186801|Clostridia T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9 DYD1_k127_5640699_4 330214.NIDE1585 1.926e-139 460.0 COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae 2|Bacteria T Bacterial regulatory protein, Fis family - - - ko:K02481,ko:K07713,ko:K07714 ko02020,map02020 M00499,M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5640699_17 583355.Caka_2405 2.224e-51 196.0 COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,46VVS@74201|Verrucomicrobia 74201|Verrucomicrobia T histidine kinase A domain protein - - - - - - - - - - - - Response_reg DYD1_k127_5640699_16 1122223.KB890688_gene1652 5.836e-52 189.0 COG2065@1|root,COG2065@2|Bacteria,1WJWR@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran DYD1_k127_5640699_7 1382356.JQMP01000003_gene1487 4.561e-115 385.0 COG0624@1|root,COG0624@2|Bacteria,2GBDE@200795|Chloroflexi,27YXE@189775|Thermomicrobia 189775|Thermomicrobia E Peptidase family M28 - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD1_k127_5640699_15 1205680.CAKO01000006_gene3183 1.242e-54 199.0 COG0461@1|root,COG0461@2|Bacteria,1MVP7@1224|Proteobacteria,2TTSB@28211|Alphaproteobacteria,2JPQH@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran DYD1_k127_5640699_11 1437448.AZRT01000035_gene3466 2.872e-85 301.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TSZ0@28211|Alphaproteobacteria 28211|Alphaproteobacteria F COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - - - - - - - - - - Amidohydro_1 DYD1_k127_5640699_5 1380394.JADL01000022_gene4 4.339e-137 450.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria,2JW26@204441|Rhodospirillales 204441|Rhodospirillales J Amidase - - - - - - - - - - - - Amidase DYD1_k127_5640699_1 1038869.AXAN01000099_gene5986 8.842e-183 579.0 COG3391@1|root,COG3391@2|Bacteria,1R78P@1224|Proteobacteria,2VJ7I@28216|Betaproteobacteria,1K6AC@119060|Burkholderiaceae 28216|Betaproteobacteria S TIGRFAM 40-residue YVTN family beta-propeller repeat - - - - - - - - - - - - - DYD1_k127_5640699_0 1449126.JQKL01000016_gene2867 1.746e-187 612.0 COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,26828@186813|unclassified Clostridiales 186801|Clostridia C Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_5640699_14 706587.Desti_1107 1.007e-56 202.0 COG2080@1|root,COG2080@2|Bacteria,1PGQD@1224|Proteobacteria,434AK@68525|delta/epsilon subdivisions,2X9WM@28221|Deltaproteobacteria,2MRQZ@213462|Syntrophobacterales 28221|Deltaproteobacteria C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_5640699_12 935840.JAEQ01000019_gene2104 1.04e-69 247.0 COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria,43PT0@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM xdhB - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_5640699_6 555793.WSK_3564 6.606e-118 394.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria,2K0G9@204457|Sphingomonadales 28211|Alphaproteobacteria F Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 DYD1_k127_5640699_19 391735.Veis_0795 4.095e-27 120.0 COG1802@1|root,COG1802@2|Bacteria,1MW9G@1224|Proteobacteria,2VJZQ@28216|Betaproteobacteria,4AD7G@80864|Comamonadaceae 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - FCD,GntR DYD1_k127_5640699_9 1403313.AXBR01000019_gene3359 9.415e-98 326.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus 91061|Bacilli P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_5640699_10 246969.TAM4_600 2.917e-96 328.0 COG3839@1|root,arCOG00177@2157|Archaea,2XTU1@28890|Euryarchaeota 28890|Euryarchaeota E COG3842 ABC-type spermidine putrescine transport systems, ATPase components - - 3.6.3.29,3.6.3.30,3.6.3.55 ko:K02010,ko:K02017,ko:K15497 ko02010,map02010 M00189,M00190,M00423 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.5,3.A.1.8 - - ABC_tran,TOBE,TOBE_2 DYD1_k127_5640699_2 266779.Meso_2926 1.639e-180 578.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,43KZ3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria H Belongs to the UbiD family ubiD - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_5640699_3 392499.Swit_3063 1.183e-156 502.0 COG2159@1|root,COG2159@2|Bacteria,1R7NS@1224|Proteobacteria,2UP6K@28211|Alphaproteobacteria,2KDHT@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase - - - ko:K15062 ko00627,ko01120,map00627,map01120 - R09277 RC00757,RC02478 ko00000,ko00001 - - - Amidohydro_2 DYD1_k127_5640699_8 1463855.JOHV01000001_gene1701 6.053e-107 362.0 COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria 201174|Actinobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske DYD1_k127_5640699_21 1532558.JL39_06905 1.402e-17 94.0 COG1840@1|root,COG1840@2|Bacteria,1PGNI@1224|Proteobacteria,2V7J9@28211|Alphaproteobacteria,4B9P8@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_11 DYD1_k127_5650228_4 1282360.ABAC460_00080 1.233e-21 103.0 COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TSFM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 DYD1_k127_5650228_1 1120972.AUMH01000002_gene2761 5.817e-114 377.0 2C1EV@1|root,33RW1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Cupin_2 DYD1_k127_5650228_9 1366050.N234_12150 1.535e-09 68.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - ko:K11210 - - - - ko00000,ko01000 - - - Glyoxalase DYD1_k127_5650228_0 671143.DAMO_0069 2.147e-194 611.0 COG1373@1|root,COG1373@2|Bacteria,2NP9F@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4143) - - - - - - - - - - - - AAA_14,DUF4143 DYD1_k127_5650228_2 1110502.TMO_0012 1.353e-85 297.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_5650228_8 237368.SCABRO_03798 4.487e-11 65.0 2EMBT@1|root,33F0S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5650228_7 237368.SCABRO_03797 2.644e-14 76.0 293PF@1|root,2ZR54@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5650228_3 330214.NIDE1693 6.228e-28 114.0 COG4185@1|root,COG4185@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Zeta_toxin DYD1_k127_5650228_6 398767.Glov_2141 1.343e-19 90.0 COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,42TT0@68525|delta/epsilon subdivisions,2WQEY@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - Zeta_toxin DYD1_k127_5650228_5 56110.Oscil6304_2505 1.282e-20 93.0 COG2886@1|root,COG2886@2|Bacteria,1G7YG@1117|Cyanobacteria,1HCR8@1150|Oscillatoriales 1117|Cyanobacteria S Uncharacterised protein family (UPF0175) - - - - - - - - - - - - UPF0175 DYD1_k127_5655002_6 945713.IALB_1309 2.804e-19 93.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_5655002_1 278963.ATWD01000001_gene1183 1.347e-89 306.0 COG1793@1|root,COG1793@2|Bacteria,3Y2VV@57723|Acidobacteria,2JIJ7@204432|Acidobacteriia 204432|Acidobacteriia L DNA ligase D, 3'-phosphoesterase domain - - - - - - - - - - - - DNA_ligase_A_C,DNA_ligase_A_M DYD1_k127_5655002_0 378806.STAUR_3269 5.809e-144 479.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria,2YUCY@29|Myxococcales 28221|Deltaproteobacteria O PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - 3.4.21.66 ko:K08651 - - - - ko00000,ko01000,ko01002,ko03110 - - - Big_2,CUB,He_PIG,Peptidase_S8 DYD1_k127_5655002_7 460265.Mnod_2388 1.306e-10 69.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,1JTF0@119045|Methylobacteriaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5655002_2 768704.Desmer_2407 8.903e-67 234.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,261PJ@186807|Peptococcaceae 186801|Clostridia S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP DYD1_k127_5655002_4 1144310.PMI07_005585 3.191e-20 102.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5655002_5 1415775.U729_302 3.964e-20 93.0 COG3183@1|root,COG3183@2|Bacteria 2|Bacteria L HNH endonuclease - - - ko:K07451,ko:K07452 - - - - ko00000,ko01000,ko02048 - - - AAA_5,DUF3578,DUF3883,HNH DYD1_k127_5655002_8 344747.PM8797T_04180 0.0002377 46.0 COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes 203682|Planctomycetes L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp DYD1_k127_5655002_3 1366050.N234_10460 8.047e-42 156.0 COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,2VZKC@28216|Betaproteobacteria,1KBNU@119060|Burkholderiaceae 28216|Betaproteobacteria S TGS domain - - - ko:K06944 - - - - ko00000 - - - MMR_HSR1,TGS DYD1_k127_5657427_6 1207076.ALAT01000187_gene2799 8.727e-29 126.0 COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,1RR61@1236|Gammaproteobacteria,1Z06J@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - SpoIIM DYD1_k127_5657427_5 861299.J421_2456 1.682e-30 131.0 COG1300@1|root,COG1714@1|root,COG1300@2|Bacteria,COG1714@2|Bacteria 2|Bacteria S RDD family - - - ko:K06384 - - - - ko00000 - - - RDD,SpoIIM DYD1_k127_5657427_2 1128421.JAGA01000002_gene1057 7.756e-72 259.0 COG1721@1|root,COG1721@2|Bacteria 2|Bacteria E protein (some members contain a von Willebrand factor type A (vWA) domain - - - - - - - - - - - - DUF11,DUF58 DYD1_k127_5657427_0 1123487.KB892841_gene4283 2.959e-102 342.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,2KW6R@206389|Rhodocyclales 206389|Rhodocyclales S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD1_k127_5657427_8 765420.OSCT_2044 3.647e-10 72.0 2E0NP@1|root,32W7Q@2|Bacteria,2G9D8@200795|Chloroflexi,375QK@32061|Chloroflexia 32061|Chloroflexia S Domain of unknown function (DUF4350) - - - - - - - - - - - - DUF4350 DYD1_k127_5657427_9 595460.RRSWK_00881 0.0002117 51.0 2E0BN@1|root,32VYU@2|Bacteria,2J07Z@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - DYD1_k127_5657427_7 1128421.JAGA01000002_gene1062 4.344e-19 97.0 COG5180@1|root,COG5180@2|Bacteria,2NRZJ@2323|unclassified Bacteria 2|Bacteria A pathogenesis CP_0034 - - ko:K02417,ko:K02519 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044,ko03012,ko03029 3.A.6.2,3.A.6.3 - - GPDPase_memb DYD1_k127_5657427_1 573370.DMR_40940 3.083e-78 274.0 COG1077@1|root,COG1077@2|Bacteria,1PNT2@1224|Proteobacteria,42ZQ5@68525|delta/epsilon subdivisions,2WUZN@28221|Deltaproteobacteria 28221|Deltaproteobacteria D Actin - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD1_k127_5657427_4 795359.TOPB45_0428 2.577e-50 195.0 COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,2GH8K@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Ami_3 - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM DYD1_k127_5657427_3 525904.Tter_2679 2.531e-55 211.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_3 DYD1_k127_5663904_1 1317124.DW2_02754 1.117e-85 286.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit - - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_5663904_0 177439.DPPB40 3.529e-129 426.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42PEC@68525|delta/epsilon subdivisions,2X5JG@28221|Deltaproteobacteria,2MMST@213118|Desulfobacterales 28221|Deltaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_5663904_3 1532558.JL39_10470 1.022e-18 90.0 COG0236@1|root,COG0236@2|Bacteria,1NHIC@1224|Proteobacteria,2UFUJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Phosphopantetheine attachment site - - - - - - - - - - - - PP-binding DYD1_k127_5663904_2 357808.RoseRS_0912 2.161e-40 161.0 COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,377HX@32061|Chloroflexia 32061|Chloroflexia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_5671661_3 1382306.JNIM01000001_gene1150 9.716e-36 136.0 COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_4 DYD1_k127_5671661_1 998088.B565_0271 1.97e-64 232.0 COG2984@1|root,COG2984@2|Bacteria 2|Bacteria S ABC transporter substrate binding protein CP_0258 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_5671661_2 425104.Ssed_1910 7.131e-64 227.0 COG0834@1|root,COG0834@2|Bacteria,1QCED@1224|Proteobacteria,1T84F@1236|Gammaproteobacteria,2QBTN@267890|Shewanellaceae 2|Bacteria ET Bacterial extracellular solute-binding proteins, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD1_k127_5671661_0 102125.Xen7305DRAFT_00022840 4.685e-119 418.0 COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G13T@1117|Cyanobacteria,3VIPY@52604|Pleurocapsales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - Cache_3-Cache_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1 DYD1_k127_5682978_1 316058.RPB_4413 1.29e-52 190.0 COG2080@1|root,COG2080@2|Bacteria,1RFP6@1224|Proteobacteria,2U75E@28211|Alphaproteobacteria,3JYY5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_5682978_0 309801.trd_A0069 2.977e-184 601.0 COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia 189775|Thermomicrobia C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_5683162_3 485913.Krac_10471 1.832e-54 207.0 COG0477@1|root,COG2814@2|Bacteria,2GBHK@200795|Chloroflexi 200795|Chloroflexi EGP Major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_3 DYD1_k127_5683162_0 398767.Glov_1868 1.634e-83 293.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,43T7S@69541|Desulfuromonadales 28221|Deltaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr DYD1_k127_5683162_1 323261.Noc_1152 2.606e-81 271.0 COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,1S3N1@1236|Gammaproteobacteria,1X23J@135613|Chromatiales 135613|Chromatiales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 DYD1_k127_5683162_2 675635.Psed_3034 2.342e-66 237.0 COG5016@1|root,COG5016@2|Bacteria,2IA4P@201174|Actinobacteria 201174|Actinobacteria C Conserved carboxylase domain - - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - HMGL-like,PYC_OADA DYD1_k127_5693564_1 1192034.CAP_6251 1.38e-82 287.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_5693564_0 375286.mma_0472 1.828e-186 588.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4729F@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctA family tctA4 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD1_k127_5746703_7 266265.Bxe_A2048 2.166e-39 149.0 COG0346@1|root,COG0346@2|Bacteria,1PK3B@1224|Proteobacteria,2W8DQ@28216|Betaproteobacteria,1K798@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD1_k127_5746703_4 933262.AXAM01000036_gene2178 2.411e-78 279.0 COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,43B26@68525|delta/epsilon subdivisions,2X6G6@28221|Deltaproteobacteria,2MKC2@213118|Desulfobacterales 28221|Deltaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD1_k127_5746703_6 1118054.CAGW01000075_gene3263 1.576e-48 184.0 COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 DYD1_k127_5746703_8 1144342.PMI40_02981 4.005e-07 63.0 COG0715@1|root,COG0715@2|Bacteria,1NURN@1224|Proteobacteria 1224|Proteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 DYD1_k127_5746703_3 1227453.C444_21236 1.143e-78 276.0 COG2141@1|root,arCOG02410@2157|Archaea 2157|Archaea C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_5746703_2 323261.Noc_2416 1.215e-84 289.0 COG3485@1|root,COG3485@2|Bacteria,1MV6K@1224|Proteobacteria,1S376@1236|Gammaproteobacteria,1X1QH@135613|Chromatiales 135613|Chromatiales Q Dioxygenase - - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C DYD1_k127_5746703_0 591158.SSMG_03661 1.203e-151 504.0 COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria 201174|Actinobacteria EQ PFAM Hydantoinase oxoprolinase hyuA - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A DYD1_k127_5746703_1 392499.Swit_2036 1.062e-94 338.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TR3I@28211|Alphaproteobacteria,2K8XH@204457|Sphingomonadales 204457|Sphingomonadales EQ Hydantoinase B/oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B DYD1_k127_5746703_5 1173263.Syn7502_03004 8.698e-54 201.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_5746703_9 1045856.EcWSU1_01939 1.378e-06 53.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,3X1P6@547|Enterobacter 1236|Gammaproteobacteria C Catalyzes the reversible hydration of fumarate to (S)- malate fumA GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1778 Fumerase,Fumerase_C DYD1_k127_5748863_2 580331.Thit_0098 1.389e-07 53.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42EPT@68295|Thermoanaerobacterales 186801|Clostridia J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind DYD1_k127_5748863_0 457570.Nther_0307 6.971e-105 354.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia 186801|Clostridia M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N DYD1_k127_5748863_1 1158318.ATXC01000001_gene1283 8.205e-87 295.0 COG0138@1|root,COG0138@2|Bacteria,2G3VH@200783|Aquificae 200783|Aquificae F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS DYD1_k127_5839917_6 909663.KI867150_gene2165 2.245e-11 74.0 COG3170@1|root,COG3170@2|Bacteria,1NHGQ@1224|Proteobacteria,42X64@68525|delta/epsilon subdivisions,2WSMQ@28221|Deltaproteobacteria,2MQPS@213462|Syntrophobacterales 28221|Deltaproteobacteria NU Putative zinc-finger - - - - - - - - - - - - DUF2275,zf-HC2 DYD1_k127_5839917_3 909663.KI867150_gene2166 6.556e-40 156.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2MRPA@213462|Syntrophobacterales 28221|Deltaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_5839917_0 264198.Reut_C6311 1.076e-114 377.0 COG0715@1|root,COG0715@2|Bacteria,1NS24@1224|Proteobacteria 1224|Proteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - NMT1_2 DYD1_k127_5839917_1 671143.DAMO_1713 3.514e-52 191.0 COG1678@1|root,COG1678@2|Bacteria 2|Bacteria K ribonucleoside-diphosphate reductase activity MA20_18155 - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 DYD1_k127_5839917_2 1121124.JNIX01000013_gene1565 5.369e-46 175.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,2KGDQ@204458|Caulobacterales 204458|Caulobacterales S Peptidase S16, lon domain protein - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg DYD1_k127_5839917_4 340177.Cag_1197 7.638e-22 98.0 2DPHZ@1|root,3325A@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5843655_14 32057.KB217478_gene2274 1.297e-17 84.0 COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 DYD1_k127_5843655_16 497965.Cyan7822_1092 4.445e-11 66.0 COG4634@1|root,COG4634@2|Bacteria,1G71Y@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5843655_17 111780.Sta7437_4008 4.249e-05 47.0 COG4634@1|root,COG4634@2|Bacteria,1G6S3@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5843655_4 1283283.ATXA01000008_gene2989 5.544e-110 363.0 COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria 201174|Actinobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_5843655_13 1122604.JONR01000001_gene1789 4.211e-30 133.0 COG3181@1|root,COG3181@2|Bacteria,1PHJF@1224|Proteobacteria,1SI76@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5843655_15 1122139.KB907899_gene3217 4.613e-12 80.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XI8B@135619|Oceanospirillales 135619|Oceanospirillales M protein involved in outer membrane biogenesis - - - ko:K07289 - - - - ko00000 - - - AsmA DYD1_k127_5843655_2 1340493.JNIF01000004_gene702 3.946e-161 524.0 COG0728@1|root,COG0728@2|Bacteria,3Y31G@57723|Acidobacteria 57723|Acidobacteria S virulence factor MVIN family protein - - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN DYD1_k127_5843655_8 1121439.dsat_1276 1.63e-60 230.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42NNX@68525|delta/epsilon subdivisions,2WJ9P@28221|Deltaproteobacteria,2M9N2@213115|Desulfovibrionales 28221|Deltaproteobacteria U secretion ATPase, PEP-CTERM locus subfamily - - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22 DYD1_k127_5843655_0 713587.THITH_11260 0.0 1104.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales 135613|Chromatiales G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 DYD1_k127_5843655_11 1123368.AUIS01000005_gene364 4.072e-42 158.0 COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,2ND5G@225057|Acidithiobacillales 225057|Acidithiobacillales S Evidence 4 Homologs of previously reported genes of - - - ko:K09700 - - - - ko00000 - - - - DYD1_k127_5843655_5 1110502.TMO_2139 2.265e-91 308.0 COG1659@1|root,COG1659@2|Bacteria,1QKHQ@1224|Proteobacteria,2TUWD@28211|Alphaproteobacteria,2JR8W@204441|Rhodospirillales 204441|Rhodospirillales S Encapsulating protein for peroxidase - - - - - - - - - - - - Linocin_M18 DYD1_k127_5843655_9 1173024.KI912148_gene4324 7.224e-53 207.0 COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1JK1R@1189|Stigonemataceae 1117|Cyanobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg DYD1_k127_5843655_1 1469607.KK073768_gene1538 8.872e-223 706.0 COG1352@1|root,COG1352@2|Bacteria,1G1W9@1117|Cyanobacteria,1HK56@1161|Nostocales 1117|Cyanobacteria NT PFAM CheR methyltransferase, SAM binding domain - - 2.1.1.80,3.1.1.61 ko:K00575,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheR,CheR_N,PAS,PAS_4,PAS_9 DYD1_k127_5843655_6 56107.Cylst_1816 1.71e-87 293.0 COG2201@1|root,COG2201@2|Bacteria,1G50Z@1117|Cyanobacteria,1HIJH@1161|Nostocales 1117|Cyanobacteria NT PFAM CheB methylesterase - - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest DYD1_k127_5843655_10 221288.JH992901_gene4520 1.077e-43 175.0 COG5002@1|root,COG5002@2|Bacteria,1G3I0@1117|Cyanobacteria,1JHS7@1189|Stigonemataceae 1117|Cyanobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_9 DYD1_k127_5843655_12 391625.PPSIR1_19949 3.494e-35 143.0 COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_9 DYD1_k127_5843655_3 1206737.BAGF01000016_gene671 5.138e-147 498.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4FVM6@85025|Nocardiaceae 201174|Actinobacteria L DNA polymerase Ligase (LigD) ligD GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N DYD1_k127_5843655_7 1232410.KI421414_gene2832 1.467e-69 240.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,43SYI@69541|Desulfuromonadales 28221|Deltaproteobacteria Q Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 DYD1_k127_5846217_13 460265.Mnod_2951 6.988e-14 75.0 COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 DYD1_k127_5846217_6 1173027.Mic7113_2967 3.631e-78 275.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 2|Bacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5846217_12 1231391.AMZF01000006_gene2822 1.009e-14 80.0 COG0662@1|root,COG0662@2|Bacteria,1NUXF@1224|Proteobacteria,2W29X@28216|Betaproteobacteria 28216|Betaproteobacteria G Cupin - - - - - - - - - - - - Cupin_2 DYD1_k127_5846217_11 1293048.CBMB010000004_gene1743 4.673e-27 119.0 COG3217@1|root,arCOG04766@2157|Archaea,2Y7HS@28890|Euryarchaeota,241HM@183963|Halobacteria 183963|Halobacteria S protein conserved in bacteria - - - - - - - - - - - - MOSC DYD1_k127_5846217_5 1121106.JQKB01000008_gene1361 7.567e-80 276.0 COG2141@1|root,COG2141@2|Bacteria,1N4HT@1224|Proteobacteria,2UEZB@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_5846217_10 504728.K649_09085 8.497e-46 168.0 COG0599@1|root,COG0599@2|Bacteria 2|Bacteria S peroxiredoxin activity pcaC - 3.1.1.24,4.1.1.44 ko:K01055,ko:K01607,ko:K14727 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991,R03470 RC00825,RC00938 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,CMD DYD1_k127_5846217_2 1411123.JQNH01000001_gene2070 1.444e-102 338.0 COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,2TU2C@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q protocatechuate 3,4-dioxygenase, beta subunit' pcaH - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C,PCDO_beta_N DYD1_k127_5846217_7 1380355.JNIJ01000044_gene5535 1.352e-63 223.0 COG3485@1|root,COG3485@2|Bacteria,1MV3B@1224|Proteobacteria,2TTZJ@28211|Alphaproteobacteria,3JSK1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Dioxygenase pcaG - 1.13.11.3 ko:K00448 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C DYD1_k127_5846217_0 1122223.KB890687_gene2936 3.058e-136 447.0 COG0015@1|root,COG0015@2|Bacteria,1WMD3@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Adenylosuccinate lyase C-terminus - - 5.5.1.2 ko:K01857 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03307 RC00902 ko00000,ko00001,ko01000 - - - Lyase_1 DYD1_k127_5846217_1 1206744.BAGL01000033_gene220 4.517e-117 386.0 COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4FZB8@85025|Nocardiaceae 201174|Actinobacteria I Coenzyme A transferase catI - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD1_k127_5846217_4 1297742.A176_05943 1.948e-82 281.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2YX8R@29|Myxococcales 28221|Deltaproteobacteria I Coenzyme A transferase - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD1_k127_5846217_9 262316.MAP_1627 1.804e-50 192.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_5846217_8 1415756.JQMY01000001_gene797 5.846e-56 210.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2PDN2@252301|Oceanicola 28211|Alphaproteobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD1_k127_5846217_14 1122915.AUGY01000118_gene6541 1.53e-10 72.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_5846217_3 1173027.Mic7113_2967 1.047e-97 332.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 2|Bacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5848085_4 477228.YO5_18967 3.146e-48 175.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD1_k127_5848085_2 240292.Ava_4115 8.96e-163 519.0 COG0334@1|root,COG0334@2|Bacteria,1G4HR@1117|Cyanobacteria,1HRGB@1161|Nostocales 1117|Cyanobacteria C Glu/Leu/Phe/Val dehydrogenase, dimerisation domain - - 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD1_k127_5848085_8 289376.THEYE_A0363 1.222e-35 141.0 COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae 40117|Nitrospirae O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_5848085_5 309801.trd_1809 2.385e-40 162.0 COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia 189775|Thermomicrobia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_5848085_7 309801.trd_1809 3.407e-36 149.0 COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia 189775|Thermomicrobia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_5848085_6 383372.Rcas_3774 1.461e-38 156.0 COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,377HX@32061|Chloroflexia 32061|Chloroflexia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_5848085_3 926550.CLDAP_14230 1.878e-76 258.0 COG1839@1|root,COG1839@2|Bacteria,2G6BH@200795|Chloroflexi 200795|Chloroflexi S Adenosine specific kinase - - - ko:K09129 - - - - ko00000 - - - Adenosine_kin DYD1_k127_5848085_1 472759.Nhal_3081 7.325e-259 825.0 COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1X042@135613|Chromatiales 135613|Chromatiales Q Phosphate acyltransferases - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C,Acyltransferase,PP-binding DYD1_k127_5848085_0 1121405.dsmv_1861 0.0 1351.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MIS4@213118|Desulfobacterales 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8,3.6.3.9 ko:K01537,ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 - - - ko00000,ko00001,ko01000,ko04147 3.A.3.1,3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,PTS_EIIA_2 DYD1_k127_5848085_9 518766.Rmar_2586 5.19e-06 49.0 COG0479@1|root,COG0479@2|Bacteria 2|Bacteria C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family asrA - - ko:K16950 ko00920,ko01120,map00920,map01120 - R00858,R10146 RC00065 ko00000,ko00001 - - - Fer4_22 DYD1_k127_585739_0 1231190.NA8A_14544 1.038e-98 335.0 COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria,43KJI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I acetyl-coa acetyltransferase - - - - - - - - - - - - - DYD1_k127_585739_8 439235.Dalk_3386 1.064e-35 141.0 COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,437V5@68525|delta/epsilon subdivisions,2X34N@28221|Deltaproteobacteria,2MNPW@213118|Desulfobacterales 28221|Deltaproteobacteria S Rubredoxin-like zinc ribbon domain (DUF35_N) - - - ko:K07068 - - - - ko00000 - - - DUF35_N,OB_aCoA_assoc DYD1_k127_585739_6 671143.DAMO_2973 8.8e-39 152.0 COG1047@1|root,COG1047@2|Bacteria,2NQ0G@2323|unclassified Bacteria 2|Bacteria O FKBP-type peptidyl-prolyl cis-trans isomerase slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C DYD1_k127_585739_3 1197906.CAJQ02000021_gene4604 2.466e-68 248.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria,3JR8H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Major Facilitator Superfamily MA20_02120 - - - - - - - - - - - MFS_1 DYD1_k127_585739_7 671143.DAMO_2973 2.927e-36 143.0 COG1047@1|root,COG1047@2|Bacteria,2NQ0G@2323|unclassified Bacteria 2|Bacteria O FKBP-type peptidyl-prolyl cis-trans isomerase slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C DYD1_k127_585739_5 485913.Krac_11396 4.758e-41 164.0 COG2141@1|root,COG2141@2|Bacteria 2|Bacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_585739_4 671143.DAMO_2973 6.075e-43 164.0 COG1047@1|root,COG1047@2|Bacteria,2NQ0G@2323|unclassified Bacteria 2|Bacteria O FKBP-type peptidyl-prolyl cis-trans isomerase slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C DYD1_k127_585739_2 56780.SYN_00042 2.613e-73 255.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42QVM@68525|delta/epsilon subdivisions,2WN3E@28221|Deltaproteobacteria,2MRIY@213462|Syntrophobacterales 28221|Deltaproteobacteria K Sir2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 DYD1_k127_585739_9 1150626.PHAMO_30061 7.321e-34 136.0 COG3428@1|root,COG3428@2|Bacteria,1N9PB@1224|Proteobacteria,2TUD0@28211|Alphaproteobacteria,2JU7A@204441|Rhodospirillales 204441|Rhodospirillales S Bacterial PH domain - - - - - - - - - - - - bPH_2 DYD1_k127_585739_1 886293.Sinac_3667 9.843e-93 308.0 COG3880@1|root,COG3880@2|Bacteria,2IYYJ@203682|Planctomycetes 203682|Planctomycetes C Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrome_C7 DYD1_k127_5859509_3 398767.Glov_1801 3.086e-94 316.0 COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2WKT1@28221|Deltaproteobacteria 28221|Deltaproteobacteria M COG4591 ABC-type transport system, involved in lipoprotein release, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_5859509_2 690850.Desaf_2619 1.704e-96 321.0 COG2834@1|root,COG2834@2|Bacteria,1R5CY@1224|Proteobacteria,42PWK@68525|delta/epsilon subdivisions,2WKW1@28221|Deltaproteobacteria,2MA8X@213115|Desulfovibrionales 28221|Deltaproteobacteria M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like DYD1_k127_5859509_1 398767.Glov_1799 8.038e-105 358.0 28IZT@1|root,2Z8X3@2|Bacteria,1R4RF@1224|Proteobacteria,42QV2@68525|delta/epsilon subdivisions,2WMYU@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5859509_0 1128427.KB904821_gene3548 3.667e-217 688.0 COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1G40A@1117|Cyanobacteria,1HI0P@1150|Oscillatoriales 1117|Cyanobacteria P Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Rhodanese DYD1_k127_5859509_5 509191.AEDB02000003_gene999 6.774e-35 135.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,25CI8@186801|Clostridia,3WJ6E@541000|Ruminococcaceae 186801|Clostridia S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE DYD1_k127_5859509_4 1906.SFRA_06160 1.993e-44 168.0 COG3245@1|root,COG3245@2|Bacteria,2IGG3@201174|Actinobacteria 201174|Actinobacteria C cytochrome - - - - - - - - - - - - - DYD1_k127_5859509_6 596154.Alide2_2182 4.758e-16 79.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VJA1@28216|Betaproteobacteria,4AF43@80864|Comamonadaceae 28216|Betaproteobacteria Q PFAM multicopper oxidase type - - 1.3.3.5 ko:K08100,ko:K14588 ko00860,ko01110,map00860,map01110 - R02394 RC01983 ko00000,ko00001,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD1_k127_5869225_1 1123229.AUBC01000013_gene2548 1.874e-16 89.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2UH3P@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - - DYD1_k127_5869225_0 1144310.PMI07_005585 1.606e-27 126.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5869225_3 1123229.AUBC01000013_gene2551 7.754e-05 53.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - TctA DYD1_k127_5869225_2 1144310.PMI07_006458 4.824e-06 53.0 COG1840@1|root,COG1840@2|Bacteria,1N9WT@1224|Proteobacteria,2UV2M@28211|Alphaproteobacteria,4BM48@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_6 DYD1_k127_5872461_7 553385.JEMF01000060_gene273 1.031e-35 142.0 COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,1S22D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S decarboxylase pcaC - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD DYD1_k127_5872461_2 1121396.KB892935_gene3861 1.612e-61 228.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales 28221|Deltaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_5872461_8 492774.JQMB01000009_gene3202 0.0003351 51.0 COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,2TTMJ@28211|Alphaproteobacteria,4BAKV@82115|Rhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily xylE - 1.13.11.2 ko:K00446 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase DYD1_k127_5872461_5 1522072.IL54_1597 2.727e-53 200.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,2K4H6@204457|Sphingomonadales 204457|Sphingomonadales P 4,5-dihydroxyphthalate decarboxylase ophC - - - - - - - - - - - NMT1,Phosphonate-bd DYD1_k127_5872461_0 335543.Sfum_4019 1.17e-296 916.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MSIG@213462|Syntrophobacterales 28221|Deltaproteobacteria S ABC transporter yjjK - 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn DYD1_k127_5872461_4 1536775.H70737_09015 1.833e-53 199.0 COG0451@1|root,COG0451@2|Bacteria,1TWPP@1239|Firmicutes,4HCTV@91061|Bacilli,26RTK@186822|Paenibacillaceae 91061|Bacilli GM epimerase - - - - - - - - - - - - Epimerase DYD1_k127_5872461_1 1120973.AQXL01000095_gene233 6.066e-134 440.0 COG4638@1|root,COG4638@2|Bacteria 2|Bacteria P Rieske (2fe-2S) narAa - 1.14.12.19 ko:K05708,ko:K11943,ko:K18251 ko00360,ko00624,ko01100,ko01120,ko01220,map00360,map00624,map01100,map01120,map01220 M00545,M00636 R05843,R06782,R06783,R09227 RC00091,RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A DYD1_k127_5872461_6 562970.Btus_2902 2.108e-49 183.0 COG5517@1|root,COG5517@2|Bacteria,1VX10@1239|Firmicutes,4HXGB@91061|Bacilli,27ABS@186823|Alicyclobacillaceae 91061|Bacilli Q SnoaL-like domain - - - - - - - - - - - - Ring_hydroxyl_B DYD1_k127_5872461_3 1307436.PBF_11192 3.852e-55 198.0 COG1028@1|root,COG1028@2|Bacteria,1U6HA@1239|Firmicutes,4IG9M@91061|Bacilli,1ZD4Y@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short DYD1_k127_5874972_3 234267.Acid_3295 8.449e-12 79.0 COG2373@1|root,COG3386@1|root,COG2373@2|Bacteria,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria 57723|Acidobacteria G PFAM NHL repeat containing protein - - - ko:K13735 ko05100,map05100 - - - ko00000,ko00001 - - - Big_1,Big_3_5,NHL DYD1_k127_5874972_1 1429851.X548_17705 2.449e-31 144.0 COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,1QXVA@1224|Proteobacteria,1T483@1236|Gammaproteobacteria,1X8K2@135614|Xanthomonadales 135614|Xanthomonadales DZ IPT/TIG domain - - - - - - - - - - - - RHS_repeat,TIG DYD1_k127_5874972_4 110319.CF8_3455 7.507e-08 66.0 COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,2GJ4T@201174|Actinobacteria,4DRCF@85009|Propionibacteriales 201174|Actinobacteria M Protein of unknown function (DUF3494) - - - - - - - - - - - - DUF3494 DYD1_k127_5874972_0 1379698.RBG1_1C00001G0584 1.431e-94 346.0 COG2373@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.4.24.40 ko:K01406,ko:K14274,ko:K20276,ko:K21449 ko00040,ko01503,ko02024,map00040,map01503,map02024 - R02427 RC00713 ko00000,ko00001,ko01000,ko01002,ko02000 1.B.40.2 - - Calx-beta,DUF4347,He_PIG,Ice_nucleation,SGL DYD1_k127_5874972_2 1216976.AX27061_0839 1.053e-27 125.0 COG0583@1|root,COG0583@2|Bacteria,1R9GY@1224|Proteobacteria,2VHIQ@28216|Betaproteobacteria,3T6ZX@506|Alcaligenaceae 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate DYD1_k127_5888213_1 1134413.ANNK01000114_gene1920 3.72e-115 383.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_5888213_0 627192.SLG_34970 5.345e-130 428.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,2K0WS@204457|Sphingomonadales 204457|Sphingomonadales P Rieske (2Fe-2S) domain-containing protein - - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_5888213_2 76114.p2A120 3.704e-112 379.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_5888213_3 443152.MDG893_15307 3.569e-72 256.0 2C1EV@1|root,33RW1@2|Bacteria,1R3AA@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_5891893_5 316067.Geob_2850 1.872e-09 62.0 COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,42R4J@68525|delta/epsilon subdivisions,2WMXH@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM import inner membrane translocase, subunit Tim44 - - - - - - - - - - - - DUF1517,Tim44 DYD1_k127_5891893_0 1123501.KB902290_gene1571 1.862e-177 576.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transport system fused permease components - - - - - - - - - - - - DctM DYD1_k127_5891893_3 1123501.KB902290_gene1570 3.545e-47 183.0 COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TRAP transporter solute receptor TAXI family protein - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD1_k127_5891893_2 1123501.KB902290_gene1570 2.147e-51 196.0 COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TRAP transporter solute receptor TAXI family protein - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD1_k127_5891893_1 1254432.SCE1572_11415 2.643e-108 362.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_5891893_4 743719.PaelaDRAFT_0962 6.985e-22 105.0 COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,26UYR@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_589271_6 1191523.MROS_1494 6.39e-11 71.0 COG2204@1|root,COG2204@2|Bacteria 2|Bacteria T phosphorelay signal transduction system - - - ko:K07714 ko02020,map02020 M00500 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_589271_0 1123072.AUDH01000002_gene2353 2.49e-107 361.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Methionine synthase MA20_07800 - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 DYD1_k127_589271_2 84531.JMTZ01000112_gene2019 4.908e-25 107.0 2E628@1|root,330RC@2|Bacteria,1N6W8@1224|Proteobacteria,1SEWI@1236|Gammaproteobacteria,1XBWI@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD1_k127_589271_1 118173.KB235914_gene1924 3.026e-26 113.0 2C7M6@1|root,32U5X@2|Bacteria,1G7T2@1117|Cyanobacteria,1HCN5@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_589271_5 864702.OsccyDRAFT_1521 1.862e-18 90.0 COG5550@1|root,COG5550@2|Bacteria,1G78M@1117|Cyanobacteria,1HBUT@1150|Oscillatoriales 1117|Cyanobacteria O TIGRFAM clan AA aspartic protease, AF_0612 family - - - - - - - - - - - - - DYD1_k127_589271_7 449447.MAE_26880 9.285e-11 64.0 COG5550@1|root,COG5550@2|Bacteria,1G73D@1117|Cyanobacteria 1117|Cyanobacteria O Clan AA aspartic protease - - - - - - - - - - - - - DYD1_k127_589271_4 1162668.LFE_1980 3.323e-20 93.0 COG5606@1|root,COG5606@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - HTH_37 DYD1_k127_589271_3 449447.MAE_33170 3.755e-24 104.0 COG4679@1|root,COG4679@2|Bacteria,1G6VG@1117|Cyanobacteria 1117|Cyanobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 DYD1_k127_5893328_21 221288.JH992901_gene4351 0.0002962 43.0 2BXJK@1|root,33AIX@2|Bacteria,1GFAX@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_5893328_16 1110697.NCAST_03_00005 1.979e-10 62.0 2DQZN@1|root,339JB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5893328_8 244582.JQAK01000022_gene652 3.577e-25 108.0 2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_5893328_9 498761.HM1_3125 5.569e-24 108.0 2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia 186801|Clostridia S ORF located using Blastx - - - - - - - - - - - - - DYD1_k127_5893328_11 865861.AZSU01000002_gene2976 7.053e-16 86.0 2CH8J@1|root,2ZMVM@2|Bacteria,1V1XK@1239|Firmicutes,24G5J@186801|Clostridia,36JG9@31979|Clostridiaceae 186801|Clostridia L LAGLIDADG DNA endonuclease family - - - - - - - - - - - - LAGLIDADG_2 DYD1_k127_5893328_3 1121447.JONL01000018_gene3728 1.194e-38 147.0 2DMHR@1|root,32RMI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5893328_17 1550091.JROE01000032_gene4174 1.124e-07 53.0 2EK6X@1|root,33DXA@2|Bacteria,4NY6H@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD1_k127_5893328_13 568703.LGG_00815 1.469e-13 70.0 2DPNJ@1|root,332SC@2|Bacteria,1VEK7@1239|Firmicutes,4II74@91061|Bacilli,3FAQA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_5893328_6 498761.HM1_3148 4.279e-29 117.0 2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_5893328_14 1232437.KL662077_gene1904 1.654e-11 64.0 2AEBV@1|root,3146B@2|Bacteria,1PTMA@1224|Proteobacteria,432JB@68525|delta/epsilon subdivisions,2WXR3@28221|Deltaproteobacteria,2MP7D@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5893328_7 1382230.ASAP_2763 4.491e-27 111.0 2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5893328_1 316067.Geob_3588 3.962e-149 489.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,43TMJ@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b DYD1_k127_5893328_2 290397.Adeh_1045 5.065e-87 296.0 COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Metallophosphoesterase - - - ko:K09769 - - - - ko00000 - - - YmdB DYD1_k127_5893328_0 1232410.KI421425_gene1521 9.136e-190 606.0 COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,43SDT@69541|Desulfuromonadales 28221|Deltaproteobacteria A Domain of unknown function (DUF3552) rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 DYD1_k127_5893328_10 349161.Dred_2882 2.036e-23 109.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,26269@186807|Peptococcaceae 186801|Clostridia H PFAM 5-formyltetrahydrofolate cyclo-ligase yqgN - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig DYD1_k127_5893328_15 649747.HMPREF0083_02301 5.491e-11 68.0 COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,26QBQ@186822|Paenibacillaceae 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA DYD1_k127_5893328_5 395495.Lcho_0048 2.974e-33 136.0 COG1999@1|root,COG1999@2|Bacteria,1N6WC@1224|Proteobacteria,2VMIP@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM electron transport protein SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD1_k127_5893328_18 886293.Sinac_3513 6.33e-07 58.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - ko:K00406,ko:K12263 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,SirB DYD1_k127_5893328_4 580327.Tthe_2448 1.27e-38 150.0 COG0864@1|root,COG0864@2|Bacteria,1V5TB@1239|Firmicutes,24HRD@186801|Clostridia,42G9E@68295|Thermoanaerobacterales 186801|Clostridia K transcriptional regulator - - - ko:K07722 - - - - ko00000,ko03000 - - - NikR_C,RHH_1 DYD1_k127_5893328_19 929703.KE386491_gene3548 2.14e-06 54.0 COG4206@1|root,COG4206@2|Bacteria,4PKCR@976|Bacteroidetes,47Y24@768503|Cytophagia 976|Bacteroidetes H TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD1_k127_5894665_0 420324.KI912061_gene6197 0.0 1047.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,1JR57@119045|Methylobacteriaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,Abhydrolase_1,Guanylate_cyc,TPR_4 DYD1_k127_5894665_1 264198.Reut_B4834 1.56e-319 1012.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae 28216|Betaproteobacteria T adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc DYD1_k127_5894665_5 566466.NOR53_2584 1.655e-35 136.0 COG3145@1|root,COG3145@2|Bacteria,1RGXU@1224|Proteobacteria,1S6DD@1236|Gammaproteobacteria,1J8C7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L 2OG-Fe(II) oxygenase superfamily alkB - - - - - - - - - - - 2OG-FeII_Oxy_2 DYD1_k127_5894665_7 882082.SaccyDRAFT_2543 2.977e-18 89.0 COG2227@1|root,COG2227@2|Bacteria,2GJAQ@201174|Actinobacteria 201174|Actinobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 DYD1_k127_5894665_2 439235.Dalk_1526 3.021e-198 660.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales 28221|Deltaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12 DYD1_k127_5894665_9 1173263.Syn7502_03004 9.182e-11 70.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_5894665_6 1173263.Syn7502_03004 1.646e-34 145.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_5894665_8 419947.MRA_2624 3.016e-14 79.0 COG1848@1|root,COG1848@2|Bacteria,2IIF6@201174|Actinobacteria 201174|Actinobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN DYD1_k127_5894665_10 419947.MRA_2623A 8.236e-10 63.0 COG2002@1|root,COG2002@2|Bacteria,2HANT@201174|Actinobacteria 201174|Actinobacteria K toxin-antitoxin pair type II binding - - - - - - - - - - - - - DYD1_k127_5894665_4 1429916.X566_05410 9.427e-82 280.0 COG2267@1|root,COG2267@2|Bacteria,1RE00@1224|Proteobacteria,2UGX6@28211|Alphaproteobacteria 28211|Alphaproteobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 DYD1_k127_5894665_3 306281.AJLK01000167_gene3839 2.855e-145 477.0 COG1351@1|root,COG1351@2|Bacteria,1GB5D@1117|Cyanobacteria,1JJ9P@1189|Stigonemataceae 1117|Cyanobacteria F Thymidylate synthase complementing protein - - - - - - - - - - - - Thy1 DYD1_k127_589580_0 497964.CfE428DRAFT_1952 4.371e-296 925.0 COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG3605@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG3605@2|Bacteria,COG5002@2|Bacteria,46Z8Q@74201|Verrucomicrobia 74201|Verrucomicrobia T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Response_reg DYD1_k127_589580_1 670292.JH26_07990 1.02e-99 352.0 COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JST2@119045|Methylobacteriaceae 28211|Alphaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD1_k127_589580_2 1267533.KB906733_gene3603 1.687e-20 94.0 2C12A@1|root,33B7C@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_5896670_19 631362.Thi970DRAFT_00658 2.633e-13 73.0 COG1848@1|root,COG1848@2|Bacteria 2|Bacteria G Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN,PIN_3 DYD1_k127_5896670_18 485913.Krac_10366 6.994e-16 80.0 COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria,2G6I4@200795|Chloroflexi 200795|Chloroflexi L PFAM helicase domain protein - - - - - - - - - - - - Helicase_C,PLDc_2,SNF2_N DYD1_k127_5896670_11 316274.Haur_2539 3.365e-55 206.0 COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria,2G6I4@200795|Chloroflexi,376H2@32061|Chloroflexia 32061|Chloroflexia KL PFAM helicase domain protein - - - - - - - - - - - - Helicase_C,PLDc_2 DYD1_k127_5896670_0 485913.Krac_10366 1.863e-196 626.0 COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria,2G6I4@200795|Chloroflexi 200795|Chloroflexi L PFAM helicase domain protein - - - - - - - - - - - - Helicase_C,PLDc_2,SNF2_N DYD1_k127_5896670_21 485913.Krac_10366 7.015e-06 52.0 COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria,2G6I4@200795|Chloroflexi 200795|Chloroflexi L PFAM helicase domain protein - - - - - - - - - - - - Helicase_C,PLDc_2,SNF2_N DYD1_k127_5896670_5 492774.JQMB01000004_gene2188 4.676e-91 312.0 COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1MX2D@1224|Proteobacteria 1224|Proteobacteria K Pfam:DUF955 - - - - - - - - - - - - HTH_19,HTH_3,HTH_31,Peptidase_M78 DYD1_k127_5896670_17 795666.MW7_1087 6.133e-20 96.0 2F49Z@1|root,33X0M@2|Bacteria,1NW3T@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_5896670_12 1122604.JONR01000010_gene3877 2.768e-53 190.0 COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,1X72V@135614|Xanthomonadales 135614|Xanthomonadales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD1_k127_5896670_1 392499.Swit_2091 3.241e-117 397.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2U2SV@28211|Alphaproteobacteria,2K9WC@204457|Sphingomonadales 204457|Sphingomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD1_k127_5896670_20 7994.ENSAMXP00000020515 5.857e-12 70.0 COG0446@1|root,KOG1336@2759|Eukaryota,38CNG@33154|Opisthokonta,3BH1J@33208|Metazoa,3CTAN@33213|Bilateria,4857Q@7711|Chordata,496S4@7742|Vertebrata,49S39@7898|Actinopterygii 33208|Metazoa S apoptosis-inducing factor AIFM3 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005783,GO:0006915,GO:0008150,GO:0008219,GO:0009987,GO:0012501,GO:0012505,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0097194 - - - - - - - - - - Pyr_redox_2,Reductase_C,Rieske DYD1_k127_5896670_7 329726.AM1_4632 3.082e-71 251.0 COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria 1117|Cyanobacteria S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB DYD1_k127_5896670_16 639282.DEFDS_1490 4.69e-21 101.0 COG3448@1|root,COG3448@2|Bacteria 2|Bacteria T diguanylate cyclase activity proV - 3.6.3.32 ko:K02000,ko:K04767,ko:K05847,ko:K07168,ko:K09137 ko02010,map02010 M00208,M00209 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,BON,CBS,DUF190,HPP DYD1_k127_5896670_9 118005.AWNK01000012_gene39 3.747e-58 206.0 COG1666@1|root,COG1666@2|Bacteria 2|Bacteria S GTP binding yajQ GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K09767 - - - - ko00000 - - - DUF520 DYD1_k127_5896670_8 323848.Nmul_A2110 1.126e-68 235.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,373GQ@32003|Nitrosomonadales 28216|Betaproteobacteria C SelR domain msrB - 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 - - - - ko00000,ko01000 - - - SelR DYD1_k127_5896670_13 926560.KE387023_gene2369 1.378e-45 170.0 COG2050@1|root,COG2050@2|Bacteria,1WJVA@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus Q Thioesterase superfamily - - - - - - - - - - - - 4HBT DYD1_k127_5896670_2 448385.sce4770 1.774e-94 319.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria 28221|Deltaproteobacteria C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD1_k127_5896670_4 3218.PP1S46_300V6.1 3.474e-91 317.0 COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta 35493|Streptophyta C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD1_k127_5896670_15 671143.DAMO_1987 1.229e-26 116.0 COG2259@1|root,COG2259@2|Bacteria,2NQ4C@2323|unclassified Bacteria 2|Bacteria S DoxX ndh - 1.6.99.3,1.8.5.2 ko:K03885,ko:K16937 ko00190,ko00920,ko01120,map00190,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxD,DoxX,Pyr_redox_2 DYD1_k127_5896670_6 321332.CYB_0151 1.554e-73 256.0 COG0491@1|root,COG0491@2|Bacteria,1G04I@1117|Cyanobacteria,1GYPD@1129|Synechococcus 1117|Cyanobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B DYD1_k127_5896670_14 292415.Tbd_0889 1.28e-40 165.0 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,2VIY7@28216|Betaproteobacteria 28216|Betaproteobacteria S FIST N domain - - - - - - - - - - - - FIST,FIST_C DYD1_k127_5896670_3 1382356.JQMP01000001_gene834 2.807e-92 325.0 COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia 189775|Thermomicrobia S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - DYD1_k127_5896670_10 502025.Hoch_0434 2.267e-56 209.0 COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria 1224|Proteobacteria E COG0665 Glycine D-amino acid oxidases (deaminating) - - 1.4.99.6 ko:K19746 ko00472,ko01100,map00472,map01100 - R11018 RC00006 ko00000,ko00001,ko01000 - - - DAO DYD1_k127_590179_0 671143.DAMO_1671 1.795e-126 408.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB - - - - - - - - - - - - Cytochrom_B_C,Cytochrome_B DYD1_k127_590179_5 1131269.AQVV01000039_gene1545 4.931e-61 215.0 COG0723@1|root,COG0723@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on diphenols and related substances as donors - - 1.10.9.1 ko:K02636,ko:K03886 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00151,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske DYD1_k127_590179_7 1120985.AUMI01000005_gene2471 5.715e-53 191.0 COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,4H2VG@909932|Negativicutes 909932|Negativicutes H Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB DYD1_k127_590179_3 1121033.AUCF01000012_gene850 1.423e-86 293.0 28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,2TTBB@28211|Alphaproteobacteria,2JSU5@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF3750) - - - - - - - - - - - - DUF3750 DYD1_k127_590179_4 335543.Sfum_3281 1.874e-65 232.0 COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,42RN3@68525|delta/epsilon subdivisions,2X6YZ@28221|Deltaproteobacteria,2MS5N@213462|Syntrophobacterales 28221|Deltaproteobacteria P ABC transporter - - 3.6.3.34 ko:K02013,ko:K05776 ko02010,map02010 M00189,M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran DYD1_k127_590179_1 264198.Reut_B5776 1.285e-101 344.0 COG2159@1|root,COG2159@2|Bacteria,1R7NS@1224|Proteobacteria,2WG6X@28216|Betaproteobacteria,1KIAN@119060|Burkholderiaceae 28216|Betaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_590179_2 1134413.ANNK01000127_gene2529 3.713e-89 304.0 COG0726@1|root,COG0726@2|Bacteria,1VA2Q@1239|Firmicutes,4HEX3@91061|Bacilli,1ZK98@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD1_k127_590179_8 1231391.AMZF01000046_gene961 4.911e-46 180.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_590179_6 264198.Reut_B5778 1.359e-54 199.0 COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1K2TY@119060|Burkholderiaceae 28216|Betaproteobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - - DYD1_k127_5916429_2 864073.HFRIS_000685 4.796e-72 256.0 COG1073@1|root,COG1073@2|Bacteria,1PJHS@1224|Proteobacteria,2VXXE@28216|Betaproteobacteria 28216|Betaproteobacteria S Belongs to the UPF0255 family - - - - - - - - - - - - DUF1100 DYD1_k127_5916429_0 926550.CLDAP_11000 1.101e-145 470.0 COG4608@1|root,COG4608@2|Bacteria 2|Bacteria P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_5916429_1 926550.CLDAP_11010 1.633e-138 447.0 COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi 200795|Chloroflexi P Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY DYD1_k127_5916429_3 1121939.L861_22655 2.48e-49 177.0 COG1173@1|root,COG1173@2|Bacteria,1R4K8@1224|Proteobacteria,1SYV4@1236|Gammaproteobacteria 1236|Gammaproteobacteria EP Pfam Binding-protein-dependent transport - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD1_k127_5917508_7 485914.Hmuk_0422 3.446e-32 138.0 arCOG08113@1|root,arCOG08113@2157|Archaea,2XV1B@28890|Euryarchaeota,23TAX@183963|Halobacteria 183963|Halobacteria S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - BNR DYD1_k127_5917508_3 257310.BB3255 6.468e-84 283.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2VKEU@28216|Betaproteobacteria,3T1GJ@506|Alcaligenaceae 28216|Betaproteobacteria O Maleylacetoacetate isomerase maiA - 5.2.1.2,5.2.1.4 ko:K01800,ko:K01801 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181,R03868 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3 DYD1_k127_5917508_9 1284352.AOIG01000006_gene2886 2.621e-24 113.0 COG1434@1|root,COG1434@2|Bacteria,1V05M@1239|Firmicutes,4IR5Y@91061|Bacilli,276NF@186822|Paenibacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 DYD1_k127_5917508_1 1123504.JQKD01000037_gene3113 8.239e-196 625.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,4AAYC@80864|Comamonadaceae 28216|Betaproteobacteria H TIGRFAM acetolactate synthase, large subunit, biosynthetic type xsc - 2.2.1.6,2.3.3.15,4.1.1.8 ko:K01577,ko:K01652,ko:K03852 ko00290,ko00430,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00430,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R01908,R03050,R04672,R04673,R05651,R08648 RC00027,RC00106,RC00620,RC01192,RC02744,RC02893,RC02903,RC02909 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_5917508_8 1089550.ATTH01000001_gene1222 5.642e-25 113.0 2AB6Z@1|root,310MA@2|Bacteria,4PF7T@976|Bacteroidetes,1FK9D@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Lipid A 3-O-deacylase (PagL) - - - - - - - - - - - - PagL DYD1_k127_5917508_4 1231391.AMZF01000009_gene1775 1.541e-78 265.0 COG0662@1|root,COG0662@2|Bacteria,1R4UW@1224|Proteobacteria 1224|Proteobacteria G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO DYD1_k127_5917508_2 1336243.JAEA01000003_gene2330 4.558e-110 365.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,1JT1V@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD1_k127_5917508_0 76114.p2A120 5.467e-198 629.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_5917508_5 47716.JOFH01000004_gene864 9.155e-39 157.0 COG0600@1|root,COG0600@2|Bacteria,2I919@201174|Actinobacteria 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_5917508_10 1173025.GEI7407_3098 1.043e-12 79.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1HAHP@1150|Oscillatoriales 1117|Cyanobacteria S metal-dependent hydrolase of the TIM-barrel fold - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5917508_6 1038858.AXBA01000058_gene4337 1.815e-36 150.0 COG0715@1|root,COG0715@2|Bacteria,1RCBF@1224|Proteobacteria,2U6AN@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - - - - - - - - - - NMT1,NMT1_2 DYD1_k127_5917508_11 1380356.JNIK01000017_gene2825 3.904e-11 68.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase,Glyoxalase_4 DYD1_k127_591836_17 247490.KSU1_D0723 2.746e-07 53.0 COG0073@1|root,COG0073@2|Bacteria,2J0IV@203682|Planctomycetes 203682|Planctomycetes J Putative tRNA binding domain - - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA_bind DYD1_k127_591836_5 330214.NIDE4041 3.295e-74 251.0 COG1592@1|root,COG1592@2|Bacteria,3J0RY@40117|Nitrospirae 40117|Nitrospirae C Rubrerythrin - - - - - - - - - - - - Rubrerythrin DYD1_k127_591836_1 330214.NIDE4040 2.12e-123 409.0 COG0247@1|root,COG1146@1|root,COG0247@2|Bacteria,COG1146@2|Bacteria 2|Bacteria C 4 iron, 4 sulfur cluster binding glpC GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 ko:K00113,ko:K00176,ko:K05524,ko:K13795,ko:K13796 ko00020,ko00564,ko00720,ko01100,ko01110,ko01120,ko01200,map00020,map00564,map00720,map01100,map01110,map01120,map01200 M00009,M00011,M00173,M00620 R00848,R01197 RC00004,RC00029,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - CCG,DUF3470,DUF3501,Fer4,Fer4_8 DYD1_k127_591836_7 502025.Hoch_2200 1.499e-44 168.0 COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales 28221|Deltaproteobacteria C Protein of unknown function (DUF3501) - - - - - - - - - - - - DUF3501 DYD1_k127_591836_13 1293054.HSACCH_01447 2.005e-25 109.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3WARF@53433|Halanaerobiales 186801|Clostridia P Belongs to the Fur family - - - ko:K09825 - - - - ko00000,ko03000 - - - FUR DYD1_k127_591836_8 1499967.BAYZ01000139_gene120 1.609e-42 162.0 COG2078@1|root,COG2078@2|Bacteria,2NPQ0@2323|unclassified Bacteria 2|Bacteria S AMMECR1 - - - ko:K06990,ko:K09141 - - - - ko00000,ko04812 - - - AMMECR1,Memo DYD1_k127_591836_12 264732.Moth_0731 5.176e-33 140.0 COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,24AHX@186801|Clostridia,42FZR@68295|Thermoanaerobacterales 186801|Clostridia S Zn-dependent hydrolases of the - - - - - - - - - - - - Lactamase_B_3 DYD1_k127_591836_10 644282.Deba_0456 7.625e-36 139.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR DYD1_k127_591836_2 338966.Ppro_0481 7.112e-103 342.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2WJS4@28221|Deltaproteobacteria,43U3J@69541|Desulfuromonadales 28221|Deltaproteobacteria M Nucleotidyl transferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD1_k127_591836_0 671143.DAMO_2569 3.243e-149 482.0 COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria 2|Bacteria P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD1_k127_591836_16 1476583.DEIPH_ctg021orf0060 1.151e-11 68.0 COG3339@1|root,COG3339@2|Bacteria,1WN6M@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 DYD1_k127_591836_11 330214.NIDE2788 4.53e-33 134.0 2EBKA@1|root,335KQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_591836_19 1038859.AXAU01000015_gene935 2.997e-05 47.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2UR9F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_591836_15 91464.S7335_3861 2.974e-14 80.0 COG0625@1|root,COG0625@2|Bacteria,1G1DY@1117|Cyanobacteria,1GYMT@1129|Synechococcus 1117|Cyanobacteria O Glutathione S-transferase gst1 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N_3 DYD1_k127_591836_9 483219.LILAB_01555 6.547e-42 168.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity estX - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 DYD1_k127_591836_3 56780.SYN_00815 3.423e-98 343.0 COG1807@1|root,COG1807@2|Bacteria,1MY0U@1224|Proteobacteria,42QGD@68525|delta/epsilon subdivisions,2WM6Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_591836_4 1121403.AUCV01000022_gene3510 1.15e-90 308.0 COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,42PE4@68525|delta/epsilon subdivisions,2WK83@28221|Deltaproteobacteria,2MPWY@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyltransferase like family 2 - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 DYD1_k127_591836_14 925409.KI911562_gene814 1.375e-17 96.0 COG1807@1|root,COG1807@2|Bacteria,4NXH6@976|Bacteroidetes,1IVBY@117747|Sphingobacteriia 976|Bacteroidetes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - DYD1_k127_591836_6 247634.GPB2148_2534 4.344e-74 256.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_591836_18 479435.Kfla_2803 2.177e-05 48.0 COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DQ0Q@85009|Propionibacteriales 201174|Actinobacteria M Glycosyl transferases group 1 - - 2.4.1.346 ko:K13668 - - R11703,R11704 - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 DYD1_k127_5919211_7 710696.Intca_2326 5.468e-10 67.0 COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4FFUB@85021|Intrasporangiaceae 201174|Actinobacteria I Acyltransferase plsC2 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_5919211_4 1121918.ARWE01000001_gene3225 7.874e-18 86.0 2EIAN@1|root,33C22@2|Bacteria,1NH5M@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_5919211_2 1499967.BAYZ01000095_gene4149 1.654e-34 137.0 COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_5919211_9 443144.GM21_0541 0.0001415 48.0 28T91@1|root,2ZFHN@2|Bacteria,1P659@1224|Proteobacteria,433I9@68525|delta/epsilon subdivisions,2WX6G@28221|Deltaproteobacteria,43VY2@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_5919211_8 237368.SCABRO_00150 9.546e-09 57.0 COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes 203682|Planctomycetes L Transposase IS200 like - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp DYD1_k127_5919211_1 330214.NIDE1495 7.906e-35 135.0 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif rbpA - - - - - - - - - - - RRM_1 DYD1_k127_5919211_5 284031.JNXD01000025_gene367 1.824e-12 73.0 COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_5919211_3 1532558.JL39_00915 4.794e-24 115.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5919211_6 345341.KUTG_08561 1.929e-12 73.0 COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria,4E4EM@85010|Pseudonocardiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_5919211_0 935840.JAEQ01000001_gene2744 1.113e-121 406.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VG2H@28211|Alphaproteobacteria,43RN4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske DYD1_k127_5925768_1 671143.DAMO_0883 3.016e-85 287.0 COG0491@1|root,COG0491@2|Bacteria,2NPD5@2323|unclassified Bacteria 2|Bacteria S Metallo-beta-lactamase superfamily pksB GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B DYD1_k127_5925768_3 502025.Hoch_5503 9.536e-33 133.0 COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,42SFZ@68525|delta/epsilon subdivisions,2WPY5@28221|Deltaproteobacteria,2Z0Z7@29|Myxococcales 28221|Deltaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese DYD1_k127_5925768_0 243231.GSU1008 7.624e-101 335.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2WIPU@28221|Deltaproteobacteria,43UK1@69541|Desulfuromonadales 28221|Deltaproteobacteria I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_5925768_2 330214.NIDE2666 8.857e-57 203.0 COG2096@1|root,COG2096@2|Bacteria 2|Bacteria S cob(I)yrinic acid a,c-diamide adenosyltransferase activity yvqK GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 ko:K00798,ko:K13821 ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130 M00122 R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268 RC00080,RC00083,RC00216,RC00242,RC00255,RC00533 ko00000,ko00001,ko00002,ko01000,ko03000 - - - Cob_adeno_trans DYD1_k127_5950005_2 627192.SLG_34970 2.894e-122 405.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,2K0WS@204457|Sphingomonadales 204457|Sphingomonadales P Rieske (2Fe-2S) domain-containing protein - - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_5950005_9 1118054.CAGW01000075_gene3261 1.33e-10 72.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_5950005_10 55952.BU52_18060 6.108e-07 60.0 COG0346@1|root,COG0346@2|Bacteria,2IHXI@201174|Actinobacteria 201174|Actinobacteria E glyoxalase bleomycin resistance protein dioxygenase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD1_k127_5950005_7 653045.Strvi_4787 7.295e-35 138.0 COG0346@1|root,COG0346@2|Bacteria,2I94W@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_5950005_3 1123060.JONP01000001_gene1641 3.716e-66 234.0 COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,2JUQX@204441|Rhodospirillales 204441|Rhodospirillales C Citrate synthase, C-terminal domain - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD1_k127_5950005_5 710111.FraQA3DRAFT_1399 2.972e-49 190.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria 201174|Actinobacteria S Pfam Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5950005_6 7668.SPU_028311-tr 1.201e-35 141.0 COG1618@1|root,2QVJ8@2759|Eukaryota,38FT1@33154|Opisthokonta,3BGUB@33208|Metazoa,3CSDG@33213|Bilateria 33208|Metazoa O nucleotide phosphatase activity, acting on free nucleotides NTPCR - 3.6.1.15 ko:K06928 ko00230,ko00730,ko01100,map00230,map00730,map01100 - R00086,R00615 RC00002 ko00000,ko00001,ko01000 - - - NTPase_1 DYD1_k127_5950005_1 1123508.JH636442_gene4074 3.754e-170 545.0 COG2055@1|root,COG2055@2|Bacteria,2J36Z@203682|Planctomycetes 203682|Planctomycetes C Malate/L-lactate dehydrogenase - - - - - - - - - - - - Ldh_2 DYD1_k127_5950005_4 1121033.AUCF01000018_gene5835 4.721e-50 191.0 COG4246@1|root,COG4246@2|Bacteria,1N7Y1@1224|Proteobacteria,2TTZW@28211|Alphaproteobacteria,2JT8T@204441|Rhodospirillales 204441|Rhodospirillales S Esterase-like activity of phytase - - - - - - - - - - - - Phytase-like DYD1_k127_5950005_0 316058.RPB_4416 1.959e-199 645.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD1_k127_5950005_8 196490.AUEZ01000005_gene3543 3.504e-24 108.0 COG4032@1|root,COG4032@2|Bacteria,1R53S@1224|Proteobacteria,2U2R8@28211|Alphaproteobacteria,3JXQJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_N DYD1_k127_5950005_11 314285.KT71_14049 3.979e-05 53.0 COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,1RRA5@1236|Gammaproteobacteria,1J7ZR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_N DYD1_k127_5960463_5 443152.MDG893_15295 5.303e-33 134.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_5960463_2 1144310.PMI07_005586 2.908e-148 493.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,4BCQJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA,TctB DYD1_k127_5960463_4 443152.MDG893_15467 6.984e-56 209.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_5960463_1 1231391.AMZF01000094_gene122 1.888e-173 561.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_5960463_3 1173027.Mic7113_2967 6.116e-73 259.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 2|Bacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_5960463_0 1366050.N234_37045 1.473e-259 827.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae 28216|Betaproteobacteria T adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc DYD1_k127_596601_1 1382306.JNIM01000001_gene2427 2.748e-52 200.0 COG0006@1|root,COG0006@2|Bacteria 2|Bacteria E proline dipeptidase activity - - - - - - - - - - - - Creatinase_N,Peptidase_M24 DYD1_k127_596601_0 118163.Ple7327_1614 2.35e-82 288.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,3VKKA@52604|Pleurocapsales 1117|Cyanobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_596601_2 986075.CathTA2_1826 3.683e-37 150.0 COG0437@1|root,COG0437@2|Bacteria,1TT2G@1239|Firmicutes,4HII4@91061|Bacilli 91061|Bacilli C 4Fe-4S ferredoxin - - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Fer4_11,Fer4_3,Fer4_7 DYD1_k127_596601_4 717785.HYPMC_0254 0.000419 52.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_596601_3 696281.Desru_1790 6.017e-20 101.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,261R6@186807|Peptococcaceae 186801|Clostridia G PFAM Class II aldolase - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II DYD1_k127_6003463_1 247490.KSU1_D0387 9.895e-190 603.0 COG0499@1|root,COG0499@2|Bacteria,2IXKQ@203682|Planctomycetes 203682|Planctomycetes H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD DYD1_k127_6003463_2 338963.Pcar_1928 7.335e-177 561.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,43TWM@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N DYD1_k127_6003463_12 768671.ThimaDRAFT_1401 8.118e-22 97.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1WYUA@135613|Chromatiales 135613|Chromatiales G Phosphotransferase System - - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr DYD1_k127_6003463_7 243231.GSU1884 1.14e-89 303.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,43U8A@69541|Desulfuromonadales 28221|Deltaproteobacteria S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 DYD1_k127_6003463_11 1125863.JAFN01000001_gene901 9.621e-47 173.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria 28221|Deltaproteobacteria G PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 DYD1_k127_6003463_13 1125863.JAFN01000001_gene902 1.492e-21 98.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria 28221|Deltaproteobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE DYD1_k127_6003463_3 1232410.KI421421_gene3588 1.242e-140 464.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales 28221|Deltaproteobacteria K Sigma-54 factor, Activator interacting domain (AID) rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD DYD1_k127_6003463_6 56780.SYN_00946 1.597e-90 304.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,2MQ7U@213462|Syntrophobacterales 28221|Deltaproteobacteria S PFAM ABC transporter lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_6003463_14 652103.Rpdx1_0049 6.027e-16 85.0 COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,3JTRX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S OstA-like protein lptA - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA DYD1_k127_6003463_9 1123371.ATXH01000004_gene1728 1.059e-53 194.0 COG1778@1|root,COG1778@2|Bacteria,2GHR2@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S haloacid dehalogenase-like hydrolase - - 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase,Hydrolase_3 DYD1_k127_6003463_4 1232410.KI421421_gene3583 1.719e-119 393.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,43S6C@69541|Desulfuromonadales 28221|Deltaproteobacteria M SIS domain kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF987.Gmet_1278 CBS,SIS DYD1_k127_6003463_5 1232410.KI421421_gene3582 2.619e-108 357.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,43T9N@69541|Desulfuromonadales 28221|Deltaproteobacteria M DAHP synthetase I family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 DYD1_k127_6003463_0 1125863.JAFN01000001_gene910 1.7e-245 771.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1276 CTP_synth_N,GATase DYD1_k127_6003463_8 1232410.KI421421_gene3580 3.57e-77 266.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43TY0@69541|Desulfuromonadales 28221|Deltaproteobacteria M Cytidylyltransferase kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 DYD1_k127_6003463_15 387631.Asulf_02047 2.784e-09 68.0 COG1794@1|root,arCOG02006@2157|Archaea,2XZJS@28890|Euryarchaeota 28890|Euryarchaeota M Hydantoin racemase - - 5.1.99.3 ko:K16841 ko00230,ko01120,map00230,map01120 - R03925 RC01027 ko00000,ko00001,ko01000 - - - Asp_Glu_race DYD1_k127_6003463_10 262316.MAP_1627 1.361e-49 190.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_6003463_16 1353529.M899_2376 9.593e-06 59.0 COG5295@1|root,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - ESPR,Peptidase_S74,YadA_anchor,YadA_head,YadA_stalk DYD1_k127_6016017_9 316067.Geob_2144 3.526e-16 80.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria,43VKP@69541|Desulfuromonadales 28221|Deltaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 DYD1_k127_6016017_1 335543.Sfum_2115 5.272e-97 326.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2MQC3@213462|Syntrophobacterales 28221|Deltaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoH - - ko:K03086,ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD1_k127_6016017_10 1111479.AXAR01000006_gene730 1.135e-08 62.0 COG3427@1|root,COG3427@2|Bacteria,1V6I3@1239|Firmicutes,4HJJD@91061|Bacilli,27A1J@186823|Alicyclobacillaceae 91061|Bacilli S Carbon monoxide dehydrogenase subunit G (CoxG) - - - ko:K09386 - - - - ko00000 - - - COXG DYD1_k127_6016017_5 398525.KB900701_gene690 2.499e-59 215.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3K3D3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_6016017_4 316058.RPB_4413 4.674e-61 216.0 COG2080@1|root,COG2080@2|Bacteria,1RFP6@1224|Proteobacteria,2U75E@28211|Alphaproteobacteria,3JYY5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_6016017_0 1134413.ANNK01000087_gene253 2.339e-163 527.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HM1D@91061|Bacilli,1ZR0K@1386|Bacillus 91061|Bacilli H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate yclC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 ko:K01612 ko00627,ko01120,ko01220,map00627,map01120,map01220 - R01238 RC00391 ko00000,ko00001,ko01000 - - - UbiD DYD1_k127_6016017_3 498848.TaqDRAFT_4223 2.749e-79 274.0 COG1277@1|root,COG1277@2|Bacteria,1WJAA@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 DYD1_k127_6016017_2 1121468.AUBR01000056_gene1488 1.269e-95 323.0 COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,42ENV@68295|Thermoanaerobacterales 186801|Clostridia V PFAM ABC transporter related - - - ko:K01990,ko:K19340 ko02010,map02010 M00254,M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 - - ABC_tran DYD1_k127_6016017_6 1499967.BAYZ01000158_gene472 1.127e-58 220.0 COG1470@1|root,COG1470@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Melibiase_2,NPCBM,NPCBM_assoc DYD1_k127_6016017_7 521460.Athe_2133 9.877e-51 184.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,42GF7@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily trmL - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD1_k127_6016017_8 56110.Oscil6304_5599 8.688e-29 116.0 COG1490@1|root,COG1490@2|Bacteria,1G5CN@1117|Cyanobacteria,1HAT1@1150|Oscillatoriales 1117|Cyanobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase DYD1_k127_6017281_9 1122599.AUGR01000005_gene1974 4.891e-17 85.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XMKX@135619|Oceanospirillales 135619|Oceanospirillales L PFAM transposase IS111A IS1328 IS1533, transposase IS116 IS110 IS902 family protein - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 DYD1_k127_6017281_0 296591.Bpro_3467 8.059e-137 443.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,4ABP9@80864|Comamonadaceae 28216|Betaproteobacteria C Luciferase family - - - - - - - - - - - - Bac_luciferase DYD1_k127_6017281_1 880072.Desac_1681 1.843e-99 332.0 COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria 1224|Proteobacteria J Methionyl-tRNA formyltransferase - - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD1_k127_6017281_5 1118054.CAGW01000061_gene2437 1.881e-53 194.0 COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4HFPC@91061|Bacilli,26X34@186822|Paenibacillaceae 91061|Bacilli S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily caiE - - - - - - - - - - - Hexapep DYD1_k127_6017281_2 189753.AXAS01000041_gene2534 8.719e-82 283.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6017281_6 335543.Sfum_3685 2.262e-32 132.0 299T8@1|root,2ZWVF@2|Bacteria,1N5QA@1224|Proteobacteria,42ZI5@68525|delta/epsilon subdivisions,2WV28@28221|Deltaproteobacteria,2MRN5@213462|Syntrophobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6017281_8 1123519.PSJM300_13335 8.555e-25 108.0 2983E@1|root,2ZV9D@2|Bacteria,1QTCK@1224|Proteobacteria,1SV2J@1236|Gammaproteobacteria,1Z3GX@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6017281_4 580340.Tlie_1398 7.353e-66 234.0 COG0384@1|root,COG0384@2|Bacteria,3TBD1@508458|Synergistetes 508458|Synergistetes S PFAM Phenazine biosynthesis PhzC PhzF protein - - - - - - - - - - - - PhzC-PhzF DYD1_k127_6017281_11 1158318.ATXC01000002_gene1619 2.171e-10 64.0 2EIPJ@1|root,33CEZ@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2283) - - - - - - - - - - - - DUF2283 DYD1_k127_6017281_10 357808.RoseRS_0377 1.204e-16 82.0 2FCS4@1|root,344V9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6017281_3 189753.AXAS01000041_gene2534 2.027e-78 273.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6017281_7 880072.Desac_0008 4.075e-27 116.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2MS9G@213462|Syntrophobacterales 28221|Deltaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD1_k127_6028243_22 62928.azo1604 1.843e-16 79.0 COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,2KV93@206389|Rhodocyclales 206389|Rhodocyclales E Putative amidoligase enzyme (DUF2126) - - - - - - - - - - - - Bact_transglu_N,DUF2126,Transglut_core DYD1_k127_6028243_0 62928.azo1603 1.162e-263 836.0 COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,2VJEU@28216|Betaproteobacteria,2KUBA@206389|Rhodocyclales 206389|Rhodocyclales S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - Alpha-E,CP_ATPgrasp_2 DYD1_k127_6028243_12 1304883.KI912532_gene1943 7.873e-100 336.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2VH3S@28216|Betaproteobacteria,2KUAT@206389|Rhodocyclales 206389|Rhodocyclales E Bacterial transglutaminase-like N-terminal region - - - - - - - - - - - - Bact_transglu_N,Transglut_core DYD1_k127_6028243_11 107636.JQNK01000009_gene3036 4.568e-102 340.0 COG0265@1|root,COG0265@2|Bacteria,1R40X@1224|Proteobacteria,2U5RD@28211|Alphaproteobacteria,36ZMC@31993|Methylocystaceae 28211|Alphaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 DYD1_k127_6028243_19 1123060.JONP01000009_gene2150 3.479e-35 147.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,2JQCA@204441|Rhodospirillales 204441|Rhodospirillales G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD1_k127_6028243_3 1123508.JH636442_gene4074 1.347e-167 533.0 COG2055@1|root,COG2055@2|Bacteria,2J36Z@203682|Planctomycetes 203682|Planctomycetes C Malate/L-lactate dehydrogenase - - - - - - - - - - - - Ldh_2 DYD1_k127_6028243_15 257310.BB2770 8.34e-61 218.0 COG1024@1|root,COG1024@2|Bacteria,1PETC@1224|Proteobacteria,2W8XP@28216|Betaproteobacteria,3T6WI@506|Alcaligenaceae 28216|Betaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD1_k127_6028243_1 316058.RPB_4416 5.102e-198 640.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD1_k127_6028243_4 1366050.N234_01090 2.885e-165 532.0 COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2WEZH@28216|Betaproteobacteria 28216|Betaproteobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_6028243_8 1333998.M2A_2216 1.107e-115 380.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,4BREC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_6028243_5 1333998.M2A_2215 6.906e-141 456.0 COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,2TVFT@28211|Alphaproteobacteria,4BRDF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid transport system permease - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_6028243_10 1469245.JFBG01000052_gene2168 2.526e-105 347.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,1X2CD@135613|Chromatiales 135613|Chromatiales E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_6028243_9 909943.HIMB100_00022330 6.817e-109 368.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria,4BPP9@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E amino acid MA20_22615 - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD1_k127_6028243_7 1232410.KI421427_gene1264 6.923e-124 409.0 COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,42R72@68525|delta/epsilon subdivisions,2WMSM@28221|Deltaproteobacteria 28221|Deltaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_6028243_26 572547.Amico_1775 0.0002544 44.0 COG1943@1|root,COG1943@2|Bacteria,3TC5I@508458|Synergistetes 508458|Synergistetes L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp DYD1_k127_6028243_16 1385518.N798_11035 1.566e-47 181.0 2E9GJ@1|root,333PP@2|Bacteria 2|Bacteria S Lysyl oxidase - - - - - - - - - - - - Lysyl_oxidase DYD1_k127_6028243_25 65497.JODV01000017_gene2951 1.308e-05 52.0 2BAER@1|root,323V6@2|Bacteria,2H8K7@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_6028243_17 1120949.KB903314_gene303 4.911e-46 180.0 COG1840@1|root,COG1840@2|Bacteria 2|Bacteria P iron ion homeostasis - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_6028243_14 246197.MXAN_4750 3.551e-78 268.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria 28221|Deltaproteobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_6028243_20 56110.Oscil6304_2890 8.172e-30 124.0 COG2402@1|root,COG2402@2|Bacteria,1G5QP@1117|Cyanobacteria,1HF6X@1150|Oscillatoriales 1117|Cyanobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07065 - - - - ko00000 - - - PIN DYD1_k127_6028243_13 1144310.PMI07_005783 3.107e-96 325.0 COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,4BGGI@82115|Rhizobiaceae 28211|Alphaproteobacteria S Galactose oxidase, central domain - - - - - - - - - - - - Kelch_1,Kelch_2,Kelch_4,Kelch_6 DYD1_k127_6028243_23 391625.PPSIR1_28478 1.113e-13 78.0 COG0607@1|root,COG3258@1|root,COG0607@2|Bacteria,COG3258@2|Bacteria 2|Bacteria C Cytochrome c soxA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 ko:K00406,ko:K03889,ko:K17222,ko:K19713 ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020 M00151,M00156,M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cytochrome_CBB3,Rhodanese DYD1_k127_6028243_21 744872.Spica_0618 2.99e-21 96.0 COG1917@1|root,COG1917@2|Bacteria,2JAJW@203691|Spirochaetes 203691|Spirochaetes S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - DYD1_k127_6028243_2 479432.Sros_3050 1.072e-182 607.0 COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria,4ENP9@85012|Streptosporangiales 201174|Actinobacteria CT Domain of unknown function (DUF4062) - - - - - - - - - - - - DUF4062,HEAT_2,NACHT DYD1_k127_6028243_18 404589.Anae109_2990 6.62e-37 143.0 COG2963@1|root,COG2963@2|Bacteria,1N1MP@1224|Proteobacteria,43BIX@68525|delta/epsilon subdivisions,2X6XD@28221|Deltaproteobacteria,2YVUT@29|Myxococcales 28221|Deltaproteobacteria L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_28,HTH_Tnp_1 DYD1_k127_6028243_6 483219.LILAB_25970 2.645e-128 421.0 COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,42MUE@68525|delta/epsilon subdivisions,2WJFZ@28221|Deltaproteobacteria,2YTXG@29|Myxococcales 28221|Deltaproteobacteria L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - rve DYD1_k127_604711_2 1121396.KB892935_gene3861 1.132e-57 217.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales 28221|Deltaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_604711_3 479434.Sthe_3144 1.525e-50 188.0 COG0346@1|root,COG0346@2|Bacteria,2G8K0@200795|Chloroflexi,27YCV@189775|Thermomicrobia 189775|Thermomicrobia E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_3 DYD1_k127_604711_1 479434.Sthe_3115 3.371e-88 302.0 COG2141@1|root,COG2141@2|Bacteria 2|Bacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_604711_0 1131814.JAFO01000001_gene1870 3.538e-182 584.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the UbiD family - - 4.1.1.98 ko:K03182,ko:K16874 ko00130,ko00365,ko01100,ko01110,ko01120,map00130,map00365,map01100,map01110,map01120 M00117 R04985,R04986,R10213 RC00391,RC03086 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_604711_4 686340.Metal_3029 2.309e-13 71.0 COG1724@1|root,COG1724@2|Bacteria,1P3W9@1224|Proteobacteria,1SSC4@1236|Gammaproteobacteria,1XGPG@135618|Methylococcales 135618|Methylococcales N HicA toxin of bacterial toxin-antitoxin, - - - - - - - - - - - - HicA_toxin DYD1_k127_6068375_0 58123.JOFJ01000001_gene2969 2.702e-222 719.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4EH6R@85012|Streptosporangiales 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 DYD1_k127_6068375_1 1169161.KB897726_gene1441 5.012e-14 80.0 COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria 201174|Actinobacteria Q Catalyzes the conversion of maleate to fumarate - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD1_k127_61138_0 234267.Acid_0587 0.0 1161.0 COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria 57723|Acidobacteria IQ Phosphate acyltransferases - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase,MFS_1 DYD1_k127_61138_2 945713.IALB_1905 1.045e-40 164.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF DYD1_k127_61138_1 530564.Psta_4192 3.979e-107 360.0 COG0204@1|root,COG0204@2|Bacteria,2IXJ7@203682|Planctomycetes 203682|Planctomycetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase DYD1_k127_61138_4 379066.GAU_1734 1.21e-16 88.0 COG1183@1|root,COG1183@2|Bacteria,1ZTJP@142182|Gemmatimonadetes 142182|Gemmatimonadetes I CDP-alcohol phosphatidyltransferase - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD1_k127_61138_3 1121930.AQXG01000006_gene823 1.453e-22 107.0 COG0204@1|root,COG0204@2|Bacteria 2|Bacteria I Acyl-transferase plsC GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51,3.1.3.3 ko:K00655,ko:K07003,ko:K15781 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase,HAD,MMPL DYD1_k127_6136766_1 330214.NIDE2714 5.058e-43 162.0 COG0250@1|root,COG0250@2|Bacteria,3J17S@40117|Nitrospirae 40117|Nitrospirae K Transcription termination factor nusG - - - - - - - - - - - - NusG DYD1_k127_6136766_2 526227.Mesil_1133 1.754e-18 91.0 2DNS7@1|root,32YWC@2|Bacteria,1WKTD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_6136766_0 861299.J421_6044 1.605e-304 944.0 COG2192@1|root,COG2192@2|Bacteria,1ZUTI@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Carbamoyltransferase C-terminus - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N DYD1_k127_6136766_4 998674.ATTE01000001_gene3668 1.305e-13 71.0 2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,1SHN2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6136766_5 596151.DesfrDRAFT_2898 4.767e-13 79.0 COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales 28221|Deltaproteobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 DYD1_k127_6141975_7 484770.UFO1_3369 4.354e-96 322.0 COG0697@1|root,COG0697@2|Bacteria,1V230@1239|Firmicutes,4H6TY@909932|Negativicutes 909932|Negativicutes EG EamA-like transporter family - - - - - - - - - - - - EamA DYD1_k127_6141975_14 1227488.C477_08463 4.983e-44 166.0 COG3217@1|root,arCOG04766@2157|Archaea,2Y7HS@28890|Euryarchaeota,241HM@183963|Halobacteria 183963|Halobacteria S protein conserved in bacteria - - - - - - - - - - - - MOSC DYD1_k127_6141975_12 665959.HMPREF1013_03105 1.863e-49 187.0 COG2513@1|root,COG2513@2|Bacteria,1V76I@1239|Firmicutes,4HJYX@91061|Bacilli,1ZEH9@1386|Bacillus 91061|Bacilli G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase DYD1_k127_6141975_10 1173024.KI912149_gene5240 9.308e-65 234.0 COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_6141975_13 330214.NIDE3307 3.963e-49 188.0 COG2813@1|root,COG2813@2|Bacteria 2|Bacteria J rRNA (guanine-N2-)-methyltransferase activity crtF GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.210,2.1.1.304,2.1.1.333 ko:K09846,ko:K13604,ko:K21460 ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110 - R07521,R07524,R07527,R07529,R07533,R07535,R09063 RC00003,RC01662,RC02082 ko00000,ko00001,ko01000 - - - Dimerisation2,Methyltransf_2,Methyltransf_25 DYD1_k127_6141975_21 762376.AXYL_05175 1.974e-13 80.0 COG0697@1|root,COG0697@2|Bacteria,1NKZB@1224|Proteobacteria,2VI02@28216|Betaproteobacteria,3T1UA@506|Alcaligenaceae 28216|Betaproteobacteria EG Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - EamA DYD1_k127_6141975_8 479434.Sthe_1496 9.544e-94 314.0 COG0351@1|root,COG0351@2|Bacteria,2G5R7@200795|Chloroflexi,27XQP@189775|Thermomicrobia 189775|Thermomicrobia H Phosphomethylpyrimidine kinase - - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin DYD1_k127_6141975_9 1121918.ARWE01000001_gene2286 2.21e-76 263.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,43S93@69541|Desulfuromonadales 28221|Deltaproteobacteria F Orotidine 5'-phosphate decarboxylase / HUMPS family pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase DYD1_k127_6141975_2 243231.GSU1460 3.046e-229 724.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales 28221|Deltaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit DYD1_k127_6141975_3 671143.DAMO_2468 3.662e-166 530.0 COG0821@1|root,COG0821@2|Bacteria,2NNPV@2323|unclassified Bacteria 2|Bacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS06430,iJN678.gcpE GcpE DYD1_k127_6141975_15 591001.Acfer_2078 7.175e-41 160.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4H41I@909932|Negativicutes 909932|Negativicutes S R3H domain protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H DYD1_k127_6141975_5 589865.DaAHT2_2556 4.611e-101 348.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MJ96@213118|Desulfobacterales 28221|Deltaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas DYD1_k127_6141975_16 665571.STHERM_c00070 3.24e-21 94.0 COG0759@1|root,COG0759@2|Bacteria,2J8TC@203691|Spirochaetes 203691|Spirochaetes S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic DYD1_k127_6141975_18 1144275.COCOR_08099 1.122e-19 93.0 COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2YVYX@29|Myxococcales 28221|Deltaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P DYD1_k127_6141975_20 246194.CHY_0001 2.281e-14 73.0 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,42HF3@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 DYD1_k127_6141975_4 1232410.KI421422_gene2029 1.094e-102 344.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales 28221|Deltaproteobacteria I NAD-dependent glycerol-3-phosphate dehydrogenase domain protein gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N DYD1_k127_6141975_0 443143.GM18_0005 0.0 1071.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,43T5S@69541|Desulfuromonadales 28221|Deltaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD1_k127_6141975_1 1232410.KI421422_gene2032 9.331e-306 956.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales 28221|Deltaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD1_k127_6141975_22 696369.KI912183_gene2805 5.978e-13 78.0 COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,2629V@186807|Peptococcaceae 186801|Clostridia H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate cobS - 2.7.8.26 ko:K02233 ko00860,ko01100,map00860,map01100 M00122 R05223,R11174 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CobS DYD1_k127_6141975_19 1208323.B30_03295 3.631e-17 88.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,2TSPG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S auxin efflux carrier family protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans DYD1_k127_6141975_23 2340.JV46_07420 3.046e-05 49.0 COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,1RQGC@1236|Gammaproteobacteria,1J6DI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans DYD1_k127_6141975_17 557598.LHK_01006 3.756e-20 101.0 COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VXH1@28216|Betaproteobacteria,2KTE0@206351|Neisseriales 206351|Neisseriales M Gram-negative bacterial TonB protein C-terminal - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD1_k127_6141975_6 338963.Pcar_0454 5.162e-100 347.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2WKAH@28221|Deltaproteobacteria,43TV7@69541|Desulfuromonadales 28221|Deltaproteobacteria P TonB dependent receptor btuB - - ko:K02014,ko:K16092 - - - - ko00000,ko02000 1.B.14,1.B.14.3 - - Plug,TonB_dep_Rec DYD1_k127_6142873_0 118168.MC7420_3515 3.682e-80 280.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 1117|Cyanobacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_6142873_1 247490.KSU1_D0749 4.101e-24 106.0 COG0551@1|root,COG0551@2|Bacteria,2J0R7@203682|Planctomycetes 203682|Planctomycetes L PFAM DNA topoisomerase type IA zn finger - - - - - - - - - - - - DUF2726,zf-C4_Topoisom DYD1_k127_6152503_14 1121440.AUMA01000002_gene2302 3.18e-12 78.0 2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CF4@68525|delta/epsilon subdivisions,2WP3G@28221|Deltaproteobacteria,2MHAR@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4 DYD1_k127_6152503_11 502025.Hoch_4931 5.769e-41 158.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales 28221|Deltaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_6152503_15 1232437.KL662001_gene4561 2.177e-11 72.0 2D8IH@1|root,32TRC@2|Bacteria,1MZ42@1224|Proteobacteria,42UE6@68525|delta/epsilon subdivisions,2WPZW@28221|Deltaproteobacteria,2MKMY@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6152503_3 1485545.JQLW01000007_gene794 6.175e-110 366.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria 1224|Proteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysM - 2.5.1.47,6.1.1.16 ko:K01883,ko:K12339 ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00359,M00360 R00897,R03132,R03601,R03650,R04859 RC00020,RC00055,RC00523,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,PALP,tRNA-synt_1e DYD1_k127_6152503_13 247490.KSU1_D0390 7.239e-32 126.0 COG1977@1|root,COG1977@2|Bacteria,2J0X5@203682|Planctomycetes 203682|Planctomycetes H ThiS family - - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD1_k127_6152503_0 247490.KSU1_D0389 3.719e-172 550.0 COG0498@1|root,COG0498@2|Bacteria,2IXWR@203682|Planctomycetes 203682|Planctomycetes E Pyridoxal-phosphate dependent enzyme - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD1_k127_6152503_6 1125863.JAFN01000001_gene1091 3.31e-85 289.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria 28221|Deltaproteobacteria H PFAM UBA THIF-type NAD FAD binding protein moeB1 - 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF DYD1_k127_6152503_4 34007.IT40_08740 3.191e-107 364.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,2PXSZ@265|Paracoccus 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD1_k127_6152503_5 1121468.AUBR01000005_gene66 8.728e-95 324.0 COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,249ED@186801|Clostridia,42G95@68295|Thermoanaerobacterales 186801|Clostridia C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Citrate_bind DYD1_k127_6152503_7 760568.Desku_1350 3.761e-83 286.0 COG0074@1|root,COG0074@2|Bacteria,1UV3X@1239|Firmicutes,24BJR@186801|Clostridia,264FR@186807|Peptococcaceae 186801|Clostridia C TIGRFAM succinyl-CoA synthetase, alpha subunit - - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Succ_CoA_lig DYD1_k127_6152503_10 285535.JOEY01000056_gene6735 1.505e-55 208.0 COG2030@1|root,COG2030@2|Bacteria,2H7MB@201174|Actinobacteria 201174|Actinobacteria I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydrat_N DYD1_k127_6152503_8 1449065.JMLL01000014_gene3263 7.793e-59 216.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2V7D9@28211|Alphaproteobacteria,43KPE@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_6 DYD1_k127_6152503_1 1054213.HMPREF9946_00382 5.222e-132 441.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,2JVYX@204441|Rhodospirillales 204441|Rhodospirillales P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 DYD1_k127_6152503_2 1121861.KB899913_gene2241 3.823e-116 384.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.30 ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11 - - ABC_tran,TOBE_2 DYD1_k127_6152503_12 247490.KSU1_D0617 6.129e-36 149.0 COG1266@1|root,COG1266@2|Bacteria,2J329@203682|Planctomycetes 203682|Planctomycetes S CAAX protease self-immunity - - - - - - - - - - - - Abi DYD1_k127_6152503_9 156889.Mmc1_0275 4.842e-56 206.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,2TTQS@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family MA20_27940 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - - - - - - - - - - adh_short DYD1_k127_6152503_16 172088.AUGA01000007_gene8374 4.38e-08 57.0 COG0457@1|root,COG0457@2|Bacteria,1QW7M@1224|Proteobacteria,2U1I6@28211|Alphaproteobacteria,3JS3H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U TPR repeat - - - - - - - - - - - - Asp_protease_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 DYD1_k127_6152704_3 436308.Nmar_0290 4.447e-54 191.0 COG3875@1|root,arCOG02046@2157|Archaea,41SK4@651137|Thaumarchaeota 651137|Thaumarchaeota S Domain of unknown function (DUF2088) - - - - - - - - - - - - - DYD1_k127_6152704_2 436308.Nmar_0289 1.02e-98 325.0 COG0461@1|root,arCOG00029@2157|Archaea,41SJU@651137|Thaumarchaeota 651137|Thaumarchaeota F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran DYD1_k127_6152704_1 436308.Nmar_0288 1.888e-116 377.0 COG5424@1|root,arCOG06031@2157|Archaea,41SJK@651137|Thaumarchaeota 651137|Thaumarchaeota H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - - DYD1_k127_6152704_0 1125863.JAFN01000001_gene559 1.391e-238 753.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria T elongation factor Tu domain 2 protein typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 DYD1_k127_6152704_6 517418.Ctha_0462 5.325e-11 70.0 COG0695@1|root,COG0695@2|Bacteria,1FEC4@1090|Chlorobi 1090|Chlorobi O glutaredoxin 2 - - - - - - - - - - - - DUF836 DYD1_k127_6152704_4 404380.Gbem_0899 3.066e-47 196.0 COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42URI@68525|delta/epsilon subdivisions,2WQ69@28221|Deltaproteobacteria,43U4E@69541|Desulfuromonadales 28221|Deltaproteobacteria M AsmA-like C-terminal region - - - - - - - - - - - - AsmA,AsmA_2,DUF3971,DUF748 DYD1_k127_6152704_7 293826.Amet_1729 0.0003134 46.0 COG3311@1|root,COG3311@2|Bacteria,1VEEK@1239|Firmicutes,24TTF@186801|Clostridia 1239|Firmicutes L TIGRFAM DNA binding domain, excisionase family - - - - - - - - - - - - HTH_17 DYD1_k127_6152704_5 243090.RB2970 7.806e-39 152.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase pmtA - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 DYD1_k127_6168724_0 420324.KI912061_gene6197 1.448e-214 687.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,1JR57@119045|Methylobacteriaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,Abhydrolase_1,Guanylate_cyc,TPR_4 DYD1_k127_6168724_12 694429.Pyrfu_0657 0.0003596 49.0 COG2405@1|root,arCOG00717@2157|Archaea,2XRYW@28889|Crenarchaeota 28889|Crenarchaeota V Domain of unknown function (DUF3368) - - - ko:K07066 - - - - ko00000 - - - DUF3368 DYD1_k127_6168724_10 497965.Cyan7822_0272 3.899e-08 57.0 2E90H@1|root,3339X@2|Bacteria,1G9EW@1117|Cyanobacteria,3KJ2F@43988|Cyanothece 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_6168724_11 391896.A1I_04695 7.588e-07 51.0 COG4679@1|root,COG4679@2|Bacteria,1QMSB@1224|Proteobacteria,2UE5S@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 DYD1_k127_6168724_4 426117.M446_7032 1.151e-27 115.0 COG3093@1|root,COG3093@2|Bacteria,1NA48@1224|Proteobacteria,2UGHZ@28211|Alphaproteobacteria,1JYXA@119045|Methylobacteriaceae 28211|Alphaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_37 DYD1_k127_6168724_7 537013.CLOSTMETH_03066 9.755e-19 93.0 COG3064@1|root,COG3064@2|Bacteria,1UKTC@1239|Firmicutes,24CAC@186801|Clostridia,3WKZE@541000|Ruminococcaceae 186801|Clostridia M Membrane - - - - - - - - - - - - - DYD1_k127_6168724_9 660470.Theba_1180 9.2e-15 77.0 COG0399@1|root,COG0399@2|Bacteria,2GE4Z@200918|Thermotogae 200918|Thermotogae J PFAM S23 ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP DYD1_k127_6168724_3 56107.Cylst_5848 3.646e-34 135.0 COG2337@1|root,COG2337@2|Bacteria,1GIQZ@1117|Cyanobacteria,1HPA0@1161|Nostocales 1117|Cyanobacteria T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD1_k127_6168724_1 671143.DAMO_1180 1.877e-164 524.0 COG3177@1|root,COG3177@2|Bacteria,2NREB@2323|unclassified Bacteria 2|Bacteria S Filamentation induced by cAMP protein fic fic - - - - - - - - - - - Fic DYD1_k127_6168724_8 227377.CBU_1788 2.581e-15 81.0 COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria 1236|Gammaproteobacteria M ORF6N domain - - - - - - - - - - - - ORF6N DYD1_k127_6168724_6 1121438.JNJA01000001_gene2632 5.351e-21 93.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2WKY2@28221|Deltaproteobacteria,2M8MH@213115|Desulfovibrionales 28221|Deltaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase DYD1_k127_6168724_2 118161.KB235918_gene77 5.041e-44 162.0 COG4679@1|root,COG4679@2|Bacteria,1G6N5@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 DYD1_k127_6168724_5 105559.Nwat_2709 2.373e-27 114.0 COG1396@1|root,COG1396@2|Bacteria,1P0VP@1224|Proteobacteria,1SSAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - - DYD1_k127_6169531_3 574087.Acear_1661 0.0005679 45.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3WAMH@53433|Halanaerobiales 186801|Clostridia L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII DYD1_k127_6169531_1 1382359.JIAL01000001_gene744 4.265e-143 463.0 COG0438@1|root,COG0438@2|Bacteria,3Y6NY@57723|Acidobacteria,2JMG8@204432|Acidobacteriia 204432|Acidobacteriia M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_6169531_0 330214.NIDE3191 1.385e-264 837.0 COG3408@1|root,COG3408@2|Bacteria,3J0Z8@40117|Nitrospirae 40117|Nitrospirae G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - - - - - - - - - - GDE_C,GDE_N_bis DYD1_k127_6169531_2 1510531.JQJJ01000010_gene2442 2.018e-50 183.0 COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,3K48K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Methyltransferase domain - - - - - - - - - - - - Methyltransf_31 DYD1_k127_6170982_6 1123228.AUIH01000010_gene4016 4.451e-11 64.0 COG0824@1|root,COG0824@2|Bacteria,1PF95@1224|Proteobacteria,1SBBS@1236|Gammaproteobacteria,1XM08@135619|Oceanospirillales 135619|Oceanospirillales S Thioesterase superfamily - - 3.1.2.23 ko:K01075 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - - 4HBT DYD1_k127_6170982_4 926549.KI421517_gene725 1.739e-72 251.0 COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family tesA - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 DYD1_k127_6170982_2 518766.Rmar_0541 1.913e-87 295.0 COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1FJY7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes Q ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD1_k127_6170982_1 1519464.HY22_07735 1.573e-204 666.0 COG3127@1|root,COG3127@2|Bacteria,1FEZB@1090|Chlorobi 1090|Chlorobi Q MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD1_k127_6170982_0 1051632.TPY_3721 4.852e-215 695.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes 1239|Firmicutes E Aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 DYD1_k127_6170982_5 1545915.JROG01000003_gene703 5.311e-15 84.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,2K1JX@204457|Sphingomonadales 204457|Sphingomonadales Q dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_6170982_7 932213.SPM24T3_06468 0.0005067 45.0 2CIZN@1|root,33BAP@2|Bacteria,1NJHF@1224|Proteobacteria,1SHYB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Superinfection immunity protein - - - - - - - - - - - - Imm_superinfect,SHOCT DYD1_k127_6170982_3 644282.Deba_0089 1.406e-80 283.0 COG2204@1|root,COG4191@1|root,COG4564@1|root,COG5000@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,COG4564@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,sCache_2 DYD1_k127_6187870_1 671143.DAMO_2187 2.605e-151 489.0 COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria 2|Bacteria E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.3,1.4.1.4 ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N,Response_reg DYD1_k127_6187870_9 1121428.DESHY_160072___1 2.638e-19 94.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae 186801|Clostridia F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like DYD1_k127_6187870_7 309801.trd_1809 7.734e-45 175.0 COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia 189775|Thermomicrobia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_6187870_2 439235.Dalk_1952 6.837e-145 471.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MN11@213118|Desulfobacterales 28221|Deltaproteobacteria S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 DYD1_k127_6187870_3 1317118.ATO8_20899 1.669e-116 387.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2TUW3@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD1_k127_6187870_4 1173023.KE650771_gene1917 2.289e-73 258.0 COG0053@1|root,COG0053@2|Bacteria,1G361@1117|Cyanobacteria 1117|Cyanobacteria P TIGRFAM cation diffusion facilitator family transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer DYD1_k127_6187870_5 671143.DAMO_1180 3.85e-72 253.0 COG3177@1|root,COG3177@2|Bacteria,2NREB@2323|unclassified Bacteria 2|Bacteria S Filamentation induced by cAMP protein fic fic - - - - - - - - - - - Fic DYD1_k127_6187870_0 478741.JAFS01000002_gene551 0.0 1200.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46SVA@74201|Verrucomicrobia,37FY0@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N DYD1_k127_6187870_6 670487.Ocepr_2130 7.517e-50 181.0 COG5502@1|root,COG5502@2|Bacteria,1WJW9@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Uncharacterized conserved protein (DUF2267) - - - - - - - - - - - - DUF2267 DYD1_k127_6187870_8 215803.DB30_0608 5.251e-38 147.0 COG0462@1|root,COG0462@2|Bacteria,1RCRN@1224|Proteobacteria,42QPH@68525|delta/epsilon subdivisions,2WMQV@28221|Deltaproteobacteria,2YU6H@29|Myxococcales 28221|Deltaproteobacteria F Phosphoribosyl synthetase-associated domain - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N DYD1_k127_6193025_5 1303518.CCALI_01431 2.574e-09 58.0 COG2361@1|root,COG2361@2|Bacteria 2|Bacteria S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 DYD1_k127_6193025_4 56780.SYN_01852 3.253e-29 121.0 COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,42SZ0@68525|delta/epsilon subdivisions,2WPIR@28221|Deltaproteobacteria,2MR6Q@213462|Syntrophobacterales 28221|Deltaproteobacteria L Domain of unknown function (DUF3883) - - - - - - - - - - - - DUF3883,Helicase_C,SNF2_N DYD1_k127_6193025_1 909663.KI867150_gene1195 2.104e-144 470.0 COG2865@1|root,COG3177@1|root,COG2865@2|Bacteria,COG3177@2|Bacteria,1PMMF@1224|Proteobacteria,43485@68525|delta/epsilon subdivisions,2X9S0@28221|Deltaproteobacteria,2MS4Z@213462|Syntrophobacterales 28221|Deltaproteobacteria K Filamentation induced by cAMP protein fic - - - - - - - - - - - - - DYD1_k127_6193025_0 383372.Rcas_1607 4.859e-222 719.0 COG0497@1|root,COG1379@1|root,COG0497@2|Bacteria,COG1379@2|Bacteria 2|Bacteria L DNA recombination yqxK - 3.1.3.97,3.6.4.12 ko:K03546,ko:K03657,ko:K07053 ko03420,ko03430,map03420,map03430 - R00188,R11188 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DUF4178,PHP_C,UvrD-helicase,UvrD_C DYD1_k127_6193025_2 357808.RoseRS_1735 1.645e-126 417.0 COG2865@1|root,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi,374XQ@32061|Chloroflexia 200795|Chloroflexi K PFAM AAA-4 family protein - - - - - - - - - - - - HATPase_c_4 DYD1_k127_6193025_3 909663.KI867150_gene2827 1.05e-40 154.0 COG1743@1|root,COG1743@2|Bacteria,1MW7U@1224|Proteobacteria,42RFU@68525|delta/epsilon subdivisions,2WNXH@28221|Deltaproteobacteria,2MRFW@213462|Syntrophobacterales 28221|Deltaproteobacteria L Protein of unknown function (DUF1156) - - - ko:K07445 - - - - ko00000 - - - DUF1156 DYD1_k127_6193543_3 32057.KB217480_gene8266 1.885e-37 144.0 28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria,1HT4Q@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_6193543_2 189753.AXAS01000041_gene2534 4.345e-81 281.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6193543_0 189753.AXAS01000041_gene2534 1.819e-91 312.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6193543_1 1225785.CM001983_gene2183 2.937e-87 292.0 COG3118@1|root,COG3118@2|Bacteria,1QTZ9@1224|Proteobacteria,1RYHE@1236|Gammaproteobacteria,2JE1S@204037|Dickeya 1236|Gammaproteobacteria O Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotrans,Thioredoxin DYD1_k127_6202765_4 1207063.P24_08344 7.815e-72 253.0 COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2UABA@28211|Alphaproteobacteria,2JT45@204441|Rhodospirillales 204441|Rhodospirillales I Carboxylesterase family - - 3.5.1.9 ko:K01432 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3 DYD1_k127_6202765_0 189753.AXAS01000075_gene6003 5.962e-97 325.0 COG0715@1|root,COG0715@2|Bacteria,1R8AT@1224|Proteobacteria,2U2Z7@28211|Alphaproteobacteria,3K3AI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - DYD1_k127_6202765_1 1123060.JONP01000012_gene2758 3.47e-85 296.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,2JS33@204441|Rhodospirillales 204441|Rhodospirillales S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_6202765_9 1097668.BYI23_C012360 2.721e-11 74.0 COG0715@1|root,COG0715@2|Bacteria,1R5H3@1224|Proteobacteria,2VIC6@28216|Betaproteobacteria,1K6GK@119060|Burkholderiaceae 28216|Betaproteobacteria M ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6202765_7 1131730.BAVI_13164 9.471e-32 136.0 COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli,1ZDX2@1386|Bacillus 91061|Bacilli S Amidohydrolase - - 4.1.1.45,4.1.1.52 ko:K03392,ko:K22213 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_6202765_8 330214.NIDE0017 3.452e-14 75.0 COG3369@1|root,COG3369@2|Bacteria,3J1A6@40117|Nitrospirae 40117|Nitrospirae S Iron-binding zinc finger CDGSH type - - - - - - - - - - - - zf-CDGSH DYD1_k127_6202765_11 547559.Nmag_0826 0.0003777 48.0 arCOG02998@1|root,arCOG02998@2157|Archaea,2XX98@28890|Euryarchaeota,23VQN@183963|Halobacteria 183963|Halobacteria S conserved protein, contains double-stranded beta-helix domain - - - - - - - - - - - - Cupin_2 DYD1_k127_6202765_2 1120949.KB903314_gene304 4.619e-75 265.0 2C1EV@1|root,33RW1@2|Bacteria,2ICZG@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_6202765_3 443152.MDG893_15015 6.072e-74 259.0 COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,1RNY1@1236|Gammaproteobacteria,46A35@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain - - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short_C2 DYD1_k127_6202765_10 1944.JOAZ01000033_gene146 2.324e-10 72.0 COG0715@1|root,COG0715@2|Bacteria,2HFTU@201174|Actinobacteria,41CZK@629295|Streptomyces griseus group 2|Bacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6202765_5 32049.SYNPCC7002_A0337 2.852e-63 219.0 COG0346@1|root,COG0346@2|Bacteria,1G504@1117|Cyanobacteria,1H0G4@1129|Synechococcus 1117|Cyanobacteria E Lactoylglutathione lyase gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD1_k127_6202765_6 391625.PPSIR1_08911 4.527e-39 156.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2X3DV@28221|Deltaproteobacteria,2YVMF@29|Myxococcales 28221|Deltaproteobacteria C 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_7 DYD1_k127_6212310_3 1038860.AXAP01000097_gene5007 1.797e-18 94.0 COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 DYD1_k127_6212310_2 1231391.AMZF01000068_gene2180 3.616e-32 139.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_6212310_1 1232410.KI421422_gene2082 6.72e-63 226.0 COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria,43V41@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF3014) - - - - - - - - - - - - DUF3014 DYD1_k127_6212310_0 439235.Dalk_4026 7.759e-101 345.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42YUK@68525|delta/epsilon subdivisions,2WTYA@28221|Deltaproteobacteria,2MMJC@213118|Desulfobacterales 28221|Deltaproteobacteria T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Sigma54_activat DYD1_k127_6213623_5 378806.STAUR_8044 4.511e-11 64.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YWB2@29|Myxococcales 28221|Deltaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD1_k127_6213623_2 485913.Krac_1828 2.574e-48 183.0 COG0596@1|root,COG0596@2|Bacteria,2G8Y9@200795|Chloroflexi 2|Bacteria S COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 DYD1_k127_6213623_0 1499967.BAYZ01000028_gene1366 3.197e-124 416.0 COG3653@1|root,COG3653@2|Bacteria,2NNQ0@2323|unclassified Bacteria 2|Bacteria Q Amidohydrolase family dan - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 DYD1_k127_6213623_1 1499967.BAYZ01000171_gene5572 4.426e-83 281.0 COG2360@1|root,COG2360@2|Bacteria 2|Bacteria O leucyltransferase activity aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans DYD1_k127_6213623_3 484770.UFO1_0327 1.374e-37 145.0 COG0346@1|root,COG0346@2|Bacteria,1V796@1239|Firmicutes 1239|Firmicutes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD1_k127_6213623_4 671143.DAMO_2924 1.827e-23 102.0 2CBGA@1|root,33A66@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6213623_6 370438.PTH_2874 1.109e-10 67.0 COG1598@1|root,COG1598@2|Bacteria,1VHGY@1239|Firmicutes,24S40@186801|Clostridia,2663A@186807|Peptococcaceae 186801|Clostridia S HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox DYD1_k127_6215575_3 1123023.JIAI01000002_gene4973 9.447e-37 153.0 COG0715@1|root,COG0715@2|Bacteria,2IDBN@201174|Actinobacteria 201174|Actinobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6215575_2 1173024.KI912153_gene32 9.898e-74 257.0 COG0600@1|root,COG0600@2|Bacteria,1G0UB@1117|Cyanobacteria 1117|Cyanobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_6215575_1 192952.MM_1360 8.247e-77 265.0 COG1116@1|root,arCOG00193@2157|Archaea,2XT97@28890|Euryarchaeota,2N9FI@224756|Methanomicrobia 224756|Methanomicrobia E PFAM ABC transporter related ssuB - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_6215575_0 483219.LILAB_21035 8.055e-89 308.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42RDN@68525|delta/epsilon subdivisions,2WMR0@28221|Deltaproteobacteria,2YUAJ@29|Myxococcales 28221|Deltaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD1_k127_6215575_4 189753.AXAS01000041_gene2534 3.721e-19 87.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_621929_2 1230476.C207_01036 2.488e-80 269.0 2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,3JT2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Nitrile hydratase, alpha chain nthA - 4.2.1.84 ko:K01721 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R02828,R04020,R05379,R05596,R07780,R07854 RC00483,RC00792,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_alpha DYD1_k127_621929_1 936455.KI421499_gene2745 1.163e-97 323.0 28I45@1|root,2Z87Q@2|Bacteria,1R432@1224|Proteobacteria,2U3PK@28211|Alphaproteobacteria,3JS7H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E NHase catalyzes the hydration of various nitrile compounds to the corresponding amides nthB - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta DYD1_k127_621929_5 189753.AXAS01000014_gene5544 5.289e-54 192.0 2E3CR@1|root,32YC0@2|Bacteria,1N9Q9@1224|Proteobacteria,2UF5B@28211|Alphaproteobacteria,3JYQP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Nitrile hydratase beta subunit MA20_29595 - - - - - - - - - - - NHase_beta DYD1_k127_621929_8 1173028.ANKO01000224_gene1260 2.091e-23 113.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 1117|Cyanobacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_621929_10 1095769.CAHF01000021_gene938 5.184e-14 76.0 COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2VNEK@28216|Betaproteobacteria,477GY@75682|Oxalobacteraceae 28216|Betaproteobacteria P ABC-type sugar transport system, permease component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 DYD1_k127_621929_4 13035.Dacsa_2787 6.57e-55 197.0 2B5J3@1|root,31YE1@2|Bacteria,1G7B5@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_621929_6 1267535.KB906767_gene3817 8.104e-49 177.0 COG5611@1|root,COG5611@2|Bacteria 2|Bacteria S PIN domain vapC - - - - - - - - - - - PIN DYD1_k127_621929_11 1089553.Tph_c03070 0.0005261 46.0 COG2002@1|root,COG2002@2|Bacteria,1VHV0@1239|Firmicutes,24UAF@186801|Clostridia,42IY6@68295|Thermoanaerobacterales 186801|Clostridia K SpoVT / AbrB like domain - - - - - - - - - - - - MazE_antitoxin DYD1_k127_621929_0 1184267.A11Q_323 5.79e-150 492.0 COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2MSXP@213481|Bdellovibrionales,2WM3N@28221|Deltaproteobacteria 213481|Bdellovibrionales K AlkA N-terminal domain ada - 3.2.2.21 ko:K13529,ko:K13530 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD DYD1_k127_621929_3 371042.NG99_18880 2.304e-59 212.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,3X6K9@551|Erwinia 1236|Gammaproteobacteria H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N DYD1_k127_621929_9 1469607.KK073768_gene3062 3.466e-21 95.0 COG4453@1|root,COG4453@2|Bacteria,1G938@1117|Cyanobacteria,1HT27@1161|Nostocales 1117|Cyanobacteria S Protein of unknown function (DUF1778) - - - - - - - - - - - - DUF1778 DYD1_k127_6223729_2 443152.MDG893_15295 1.412e-61 224.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_6223729_0 443152.MDG893_15387 1.812e-151 502.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD1_k127_6223729_4 247490.KSU1_C0530 1.45e-09 64.0 COG3344@1|root,COG3344@2|Bacteria,2IZGP@203682|Planctomycetes 203682|Planctomycetes L Reverse transcriptase (RNA-dependent DNA polymerase) - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,RVT_1 DYD1_k127_6223729_1 1380350.JIAP01000003_gene4884 1.374e-81 279.0 COG1028@1|root,COG1028@2|Bacteria,1R6C1@1224|Proteobacteria,2U69X@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 DYD1_k127_6223729_3 1429046.RR21198_1867 2.375e-12 75.0 COG5553@1|root,COG5553@2|Bacteria,2I8K9@201174|Actinobacteria,4G4FV@85025|Nocardiaceae 201174|Actinobacteria S metal-dependent enzyme of the double-stranded beta helix superfamily - - - - - - - - - - - - CDO_I DYD1_k127_6228655_0 331869.BAL199_22237 7.342e-63 227.0 COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,2TR13@28211|Alphaproteobacteria,4BQV1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_6228655_1 639030.JHVA01000001_gene2577 3.171e-60 209.0 COG1793@1|root,COG1793@2|Bacteria,3Y45N@57723|Acidobacteria,2JIH0@204432|Acidobacteriia 204432|Acidobacteriia L ATP dependent DNA ligase C terminal region - - - - - - - - - - - - DNA_ligase_A_C,DNA_ligase_A_M DYD1_k127_6230867_0 1118235.CAJH01000040_gene2575 5.203e-117 399.0 COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,1RNZM@1236|Gammaproteobacteria,1X4Z4@135614|Xanthomonadales 135614|Xanthomonadales M protein involved in outer membrane biogenesis asmA - - ko:K07290 - - - - ko00000 9.B.121 - - AsmA DYD1_k127_6230867_1 278963.ATWD01000001_gene2187 1.696e-61 233.0 COG3267@1|root,COG3267@2|Bacteria,3Y6P4@57723|Acidobacteria,2JKNX@204432|Acidobacteriia 204432|Acidobacteriia U AAA domain - - - - - - - - - - - - AAA_22 DYD1_k127_6233775_0 420324.KI912061_gene6197 1.1e-186 594.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,1JR57@119045|Methylobacteriaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,Abhydrolase_1,Guanylate_cyc,TPR_4 DYD1_k127_6233775_1 933262.AXAM01000028_gene3322 9.093e-28 119.0 COG2337@1|root,COG2337@2|Bacteria,1RIPH@1224|Proteobacteria,42UKM@68525|delta/epsilon subdivisions,2WQZB@28221|Deltaproteobacteria,2MMDH@213118|Desulfobacterales 28221|Deltaproteobacteria T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD1_k127_623769_1 335543.Sfum_0682 3.843e-137 442.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2MQAR@213462|Syntrophobacterales 28221|Deltaproteobacteria J TIGRFAM Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b DYD1_k127_623769_4 338963.Pcar_1299 8.269e-66 234.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales 28221|Deltaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA DYD1_k127_623769_5 269799.Gmet_1958 1.049e-51 190.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,43US2@69541|Desulfuromonadales 28221|Deltaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB DYD1_k127_623769_3 429009.Adeg_1292 4.701e-73 254.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_623769_0 926550.CLDAP_00500 5.1e-155 498.0 COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2G5TN@200795|Chloroflexi 200795|Chloroflexi HP PFAM UBA THIF-type NAD FAD binding protein - - 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF DYD1_k127_623769_7 1120977.JHUX01000004_gene2208 1.718e-35 149.0 COG2199@1|root,COG3706@2|Bacteria,1PDYV@1224|Proteobacteria,1RWNP@1236|Gammaproteobacteria,3NPID@468|Moraxellaceae 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GAF,GGDEF DYD1_k127_623769_2 1173027.Mic7113_2544 9.366e-91 308.0 COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Ribonuclease BN-like family - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB DYD1_k127_623769_8 1144325.PMI22_03838 1.07e-11 66.0 COG1073@1|root,COG1073@2|Bacteria,1NXZW@1224|Proteobacteria 1224|Proteobacteria S COG1073 hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - Peptidase_S9 DYD1_k127_623769_6 1123368.AUIS01000032_gene1398 1.141e-44 171.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Pfam SNARE associated Golgi protein - - - - - - - - - - - - PLDc,PLDc_2,SNARE_assoc DYD1_k127_623769_9 316274.Haur_0818 4.346e-05 52.0 COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia 32061|Chloroflexia K Two component transcriptional regulator, winged helix family - - - - - - - - - - - - Response_reg,Trans_reg_C DYD1_k127_6238287_2 639283.Snov_4142 4.605e-85 291.0 COG0715@1|root,COG0715@2|Bacteria,1R4AB@1224|Proteobacteria,2U2A0@28211|Alphaproteobacteria,3F150@335928|Xanthobacteraceae 28211|Alphaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6238287_10 710686.Mycsm_05622 6.058e-06 51.0 COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae 201174|Actinobacteria T guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc DYD1_k127_6238287_7 649747.HMPREF0083_06230 7.723e-37 146.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,4HIMD@91061|Bacilli,26TDP@186822|Paenibacillaceae 91061|Bacilli T CHASE2 - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc DYD1_k127_6238287_6 1110502.TMO_0012 1.361e-54 205.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_6238287_4 443152.MDG893_15295 3.455e-61 226.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_6238287_8 1449065.JMLL01000010_gene1531 1.01e-36 145.0 COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria,43KNU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S protein possibly involved in utilization of glycolate and propanediol MA20_43165 - - - - - - - - - - - Haem_degrading DYD1_k127_6238287_1 331869.BAL199_16353 6.756e-240 753.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,4BPZA@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_6238287_9 93220.LV28_02775 3.999e-34 136.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria,1K74B@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_6238287_0 316058.RPB_3096 1.919e-258 821.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_6238287_5 309801.trd_0578 9.314e-60 211.0 COG2080@1|root,COG2080@2|Bacteria,2GBQV@200795|Chloroflexi,27Y9S@189775|Thermomicrobia 189775|Thermomicrobia C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_6238287_3 316067.Geob_2492 6.421e-77 265.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2WMNQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_6249445_7 555779.Dthio_PD3143 5.637e-17 81.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MEHZ@213115|Desulfovibrionales 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase DYD1_k127_6249445_1 671143.DAMO_1587 6.991e-54 195.0 COG0526@1|root,COG0526@2|Bacteria,2NPYK@2323|unclassified Bacteria 2|Bacteria O Thioredoxin-like dsbE - - ko:K02199,ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - AhpC-TSA,Redoxin,Thioredoxin DYD1_k127_6249445_5 478741.JAFS01000002_gene875 1.688e-37 149.0 COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD1_k127_6249445_2 1125863.JAFN01000001_gene2524 5.663e-53 195.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD1_k127_6249445_4 1408303.JNJJ01000078_gene1182 2.108e-38 153.0 COG2020@1|root,COG2020@2|Bacteria,1UXZ3@1239|Firmicutes 1239|Firmicutes O Methyltransferase - - - - - - - - - - - - PEMT DYD1_k127_6249445_8 671143.DAMO_1694 0.0001872 48.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - 1.11.1.15 ko:K03386,ko:K03564,ko:K16922 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko01002,ko04147 - - - AhpC-TSA,Redoxin DYD1_k127_6249445_3 926569.ANT_28370 3.05e-41 160.0 COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi 200795|Chloroflexi O PFAM DSBA oxidoreductase - - - - - - - - - - - - Thioredoxin_4 DYD1_k127_6249445_6 309801.trd_A0739 9.314e-31 130.0 COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia 189775|Thermomicrobia CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA DYD1_k127_6249445_0 886293.Sinac_3660 1.098e-78 270.0 COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes 203682|Planctomycetes S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD1_k127_6265143_1 713587.THITH_17365 6.011e-83 293.0 COG0574@1|root,COG3173@1|root,COG0574@2|Bacteria,COG3173@2|Bacteria,1Q33X@1224|Proteobacteria,1RNSN@1236|Gammaproteobacteria 1236|Gammaproteobacteria GT COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 ko:K01007,ko:K21787 ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00374,M00837,M00838 R00199,R11662,R11673 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N DYD1_k127_6265143_0 1492737.FEM08_05310 2.072e-112 371.0 COG2227@1|root,COG2227@2|Bacteria,4PK4H@976|Bacteroidetes,1ID51@117743|Flavobacteriia,2NXC0@237|Flavobacterium 976|Bacteroidetes H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 DYD1_k127_6268507_9 196367.JNFG01000011_gene6225 1.72e-40 152.0 COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,2WEMC@28216|Betaproteobacteria 28216|Betaproteobacteria C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 DYD1_k127_6268507_5 446470.Snas_5605 2.355e-69 244.0 COG0600@1|root,COG0600@2|Bacteria 2|Bacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_6268507_3 1123023.JIAI01000003_gene2636 4.284e-98 326.0 COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4E1PS@85010|Pseudonocardiales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - AAA_assoc_C,ABC_tran DYD1_k127_6268507_6 1123023.JIAI01000003_gene2637 1.235e-64 231.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD1_k127_6268507_10 391937.NA2_01689 3.129e-30 132.0 COG0715@1|root,COG0715@2|Bacteria,1R4AB@1224|Proteobacteria,2U2A0@28211|Alphaproteobacteria,43N79@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6268507_8 706587.Desti_1107 1.781e-52 189.0 COG2080@1|root,COG2080@2|Bacteria,1PGQD@1224|Proteobacteria,434AK@68525|delta/epsilon subdivisions,2X9WM@28221|Deltaproteobacteria,2MRQZ@213462|Syntrophobacterales 28221|Deltaproteobacteria C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD1_k127_6268507_0 309801.trd_A0069 3.05e-220 710.0 COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia 189775|Thermomicrobia C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_6268507_7 1380390.JIAT01000010_gene3358 2.665e-59 216.0 COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria 201174|Actinobacteria C Dehydrogenase - - - - - - - - - - - - FAD_binding_5 DYD1_k127_6268507_1 309801.trd_A0069 2.873e-196 638.0 COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia 189775|Thermomicrobia C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_6268507_2 76114.p2A120 1.482e-125 417.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_6268507_4 1122917.KB899665_gene3996 1.793e-94 328.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HM1D@91061|Bacilli,26TE8@186822|Paenibacillaceae 91061|Bacilli H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate and vanillate yclC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 ko:K01612,ko:K16874 ko00365,ko00627,ko01120,ko01220,map00365,map00627,map01120,map01220 - R01238,R10213 RC00391,RC03086 ko00000,ko00001,ko01000 - - - UbiD DYD1_k127_6292282_4 204669.Acid345_0751 1.086e-20 95.0 COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria,2JICQ@204432|Acidobacteriia 204432|Acidobacteriia T PFAM Response regulator receiver domain - - - ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_6292282_3 1122915.AUGY01000118_gene6536 5.94e-31 136.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_6292282_0 443152.MDG893_15467 8.793e-53 199.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_6292282_2 1144310.PMI07_005447 1.654e-50 193.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_6292282_1 443152.MDG893_15075 1.437e-52 199.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_632008_0 105559.Nwat_1126 0.0 1160.0 COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria,1WWTE@135613|Chromatiales 135613|Chromatiales C PFAM 4Fe-4S - - - ko:K00184,ko:K21308 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R11487 RC00168 ko00000,ko00001 5.A.3 - - Fer4_11,Fer4_4,Fer4_7 DYD1_k127_632008_1 1128421.JAGA01000003_gene2871 6.031e-13 71.0 COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria 2|Bacteria C Polysulphide reductase, NrfD nrfD - - ko:K00185 - - - - ko00000 5.A.3 - - DUF3341,NrfD DYD1_k127_6341569_3 1111728.ATYS01000017_gene3193 1.069e-26 121.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator yeiE GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - HTH_1,LysR_substrate DYD1_k127_6341569_4 1131814.JAFO01000001_gene4161 2.601e-24 114.0 COG0451@1|root,COG0451@2|Bacteria,1R5DG@1224|Proteobacteria,2TWFF@28211|Alphaproteobacteria,3F02Y@335928|Xanthobacteraceae 28211|Alphaproteobacteria M GDP-mannose 4,6 dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD1_k127_6341569_1 502025.Hoch_0231 1.657e-64 243.0 COG2425@1|root,COG2425@2|Bacteria,1N1RQ@1224|Proteobacteria,42Z19@68525|delta/epsilon subdivisions,2WZHK@28221|Deltaproteobacteria,2Z261@29|Myxococcales 28221|Deltaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA_CoxE DYD1_k127_6341569_0 502025.Hoch_0230 2.021e-107 360.0 COG0714@1|root,COG0714@2|Bacteria,1QE6X@1224|Proteobacteria,42ZU7@68525|delta/epsilon subdivisions,2X397@28221|Deltaproteobacteria,2YUWS@29|Myxococcales 28221|Deltaproteobacteria S associated with various cellular activities - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_5 DYD1_k127_6341569_2 1123023.JIAI01000002_gene5491 6.185e-57 217.0 COG1233@1|root,COG1233@2|Bacteria 2|Bacteria Q all-trans-retinol 13,14-reductase activity - - - - - - - - - - - - Amino_oxidase,DAO,NAD_binding_8 DYD1_k127_643461_12 1038867.AXAY01000025_gene2007 1.268e-16 79.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,BTAD,DZR,Guanylate_cyc,SAM_1,Trans_reg_C DYD1_k127_643461_13 545695.TREAZ_1724 3.473e-08 65.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_643461_8 1057002.KB905370_gene2083 1.907e-69 247.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TT48@28211|Alphaproteobacteria,4BDNI@82115|Rhizobiaceae 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033,ko:K13890 ko02010,ko02024,map02010,map02024 M00239,M00348 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.11 - - BPD_transp_1 DYD1_k127_643461_6 472175.EL18_02584 1.996e-79 274.0 COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2VF93@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD1_k127_643461_9 985665.HPL003_03490 2.049e-30 138.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae 91061|Bacilli E ABC transporter substrate-binding protein - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD1_k127_643461_4 941824.TCEL_00533 4.018e-96 340.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,36EGD@31979|Clostridiaceae 186801|Clostridia P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_643461_3 292459.STH2824 8.522e-101 353.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia 186801|Clostridia P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD1_k127_643461_7 1173027.Mic7113_2967 7.26e-71 252.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 2|Bacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_643461_0 1231391.AMZF01000094_gene122 2.076e-176 570.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_643461_11 1122915.AUGY01000118_gene6536 7.317e-23 112.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_643461_14 1323663.AROI01000008_gene2627 2.439e-05 54.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria 1224|Proteobacteria C uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center rubA GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575 - - - - - - - - - - Rubredoxin DYD1_k127_643461_5 626887.J057_17025 1.364e-79 276.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,1RSIB@1236|Gammaproteobacteria,466HY@72275|Alteromonadaceae 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD1_k127_643461_10 1227499.C493_11237 6.232e-27 121.0 COG0697@1|root,arCOG00272@2157|Archaea,2XVSM@28890|Euryarchaeota,23S7J@183963|Halobacteria 183963|Halobacteria G COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD1_k127_643461_1 469383.Cwoe_4082 1.978e-121 397.0 COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CRBS@84995|Rubrobacteria 84995|Rubrobacteria C PFAM Transketolase central region - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD1_k127_643461_2 469383.Cwoe_4083 9.628e-108 356.0 COG1071@1|root,COG1071@2|Bacteria,2HVS4@201174|Actinobacteria 201174|Actinobacteria C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD1_k127_6435007_8 396588.Tgr7_2375 6.483e-42 167.0 COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,1RZ5C@1236|Gammaproteobacteria 1236|Gammaproteobacteria G deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD1_k127_6435007_5 330214.NIDE2860 3.582e-76 270.0 COG3919@1|root,COG3919@2|Bacteria,3J15R@40117|Nitrospirae 40117|Nitrospirae T ATP-grasp domain - - - - - - - - - - - - - DYD1_k127_6435007_9 693661.Arcve_1656 3.583e-06 59.0 COG0613@1|root,arCOG00302@2157|Archaea,2XSWE@28890|Euryarchaeota,2469I@183980|Archaeoglobi 183980|Archaeoglobi S PFAM PHP domain - - - - - - - - - - - - PHP,PHP_C DYD1_k127_6435007_4 330214.NIDE2854 4.103e-83 289.0 COG0438@1|root,COG0438@2|Bacteria,3J15E@40117|Nitrospirae 40117|Nitrospirae M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_6435007_2 443143.GM18_1661 3.403e-96 328.0 COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,43V8U@69541|Desulfuromonadales 28221|Deltaproteobacteria M PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD1_k127_6435007_3 1499967.BAYZ01000074_gene2109 3.045e-95 338.0 COG4191@1|root,COG4191@2|Bacteria 2|Bacteria T Histidine kinase prsK - - - - - - - - - - - GAF_2,GAF_3,HATPase_c DYD1_k127_6435007_0 243231.GSU1940 8.492e-136 446.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Q6R@68525|delta/epsilon subdivisions,2WJN4@28221|Deltaproteobacteria,43TK0@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domains REC, sigma54 interaction, HTH8 - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_6435007_6 330214.NIDE2853 7.33e-65 238.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups sypH - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_6435007_1 1121430.JMLG01000002_gene1226 5.623e-121 399.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,26040@186807|Peptococcaceae 186801|Clostridia G Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 DYD1_k127_6435007_7 1134474.O59_000729 1.335e-59 219.0 COG0438@1|root,COG0438@2|Bacteria,1MWU0@1224|Proteobacteria,1RZA8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferases group 1 wblG - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_6450029_6 933262.AXAM01000094_gene2196 5.226e-92 316.0 COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MIJE@213118|Desulfobacterales 28221|Deltaproteobacteria M PFAM MltA - - - ko:K08304 - - - - ko00000,ko01000,ko01011 - GH102 - 3D,MltA DYD1_k127_6450029_10 706587.Desti_2416 3.654e-75 267.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WKKK@28221|Deltaproteobacteria 28221|Deltaproteobacteria P TIGRFAM cation diffusion facilitator family transporter dmeF - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux DYD1_k127_6450029_13 1121406.JAEX01000003_gene1560 6.962e-50 194.0 COG0477@1|root,COG2814@2|Bacteria,1PG3D@1224|Proteobacteria,42S62@68525|delta/epsilon subdivisions,2WNYR@28221|Deltaproteobacteria,2MGPZ@213115|Desulfovibrionales 28221|Deltaproteobacteria EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1,Sugar_tr DYD1_k127_6450029_20 1125863.JAFN01000001_gene1564 7.29e-24 102.0 COG1415@1|root,COG1415@2|Bacteria,1QQ3V@1224|Proteobacteria,42PEE@68525|delta/epsilon subdivisions,2WJBY@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Protein of unknown function (DUF763) - - - ko:K09003 - - - - ko00000 - - - DUF763 DYD1_k127_6450029_1 56780.SYN_01931 3.214e-257 835.0 COG2885@1|root,COG2982@1|root,COG2885@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria,2MQYM@213462|Syntrophobacterales 28221|Deltaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748 DYD1_k127_6450029_19 481448.Minf_0575 4.144e-26 113.0 COG2105@1|root,COG2105@2|Bacteria 2|Bacteria F PFAM AIG2 family protein - - - - - - - - - - - - AIG2_2,GGACT,Gamma_PGA_hydro DYD1_k127_6450029_17 671143.DAMO_2217 3.496e-28 122.0 COG2854@1|root,COG2854@2|Bacteria 2|Bacteria Q intermembrane phospholipid transfer - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD1_k127_6450029_8 1125973.JNLC01000010_gene1772 2.318e-77 271.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2VG8G@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Ornithine cyclodeaminase/mu-crystallin family - - - - - - - - - - - - OCD_Mu_crystall DYD1_k127_6450029_4 935840.JAEQ01000009_gene1332 3.278e-126 424.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,43GZZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria EH PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_6450029_12 443152.MDG893_15085 6.243e-54 203.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_6450029_18 1214242.B446_29610 4.023e-27 126.0 COG1716@1|root,COG1994@1|root,COG1716@2|Bacteria,COG1994@2|Bacteria,2IBWH@201174|Actinobacteria 201174|Actinobacteria O Peptidase M50 - - - ko:K16922 - - - - ko00000,ko01002 - - - AhpC-TSA,FHA,Yop-YscD_cpl,cNMP_binding DYD1_k127_6450029_21 298653.Franean1_0328 1.523e-17 89.0 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4ESG1@85013|Frankiales 201174|Actinobacteria K PFAM Cyclic nucleotide-binding glxR GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding DYD1_k127_6450029_5 1192034.CAP_6251 6.199e-95 323.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_6450029_9 368407.Memar_0380 4.036e-77 271.0 COG0389@1|root,arCOG04582@2157|Archaea,2XTZZ@28890|Euryarchaeota,2NAE4@224756|Methanomicrobia 224756|Methanomicrobia L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis dbh - 2.7.7.7 ko:K04479 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH DYD1_k127_6450029_14 710686.Mycsm_01832 7.044e-47 181.0 COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria 201174|Actinobacteria S NMT1-like family - - - - - - - - - - - - NMT1_3 DYD1_k127_6450029_7 1411123.JQNH01000001_gene964 9.2e-90 299.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the GST superfamily MA20_22025 - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N,GST_N_3 DYD1_k127_6450029_2 1231391.AMZF01000094_gene122 7.24e-177 572.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_6450029_0 357808.RoseRS_4018 8.378e-265 836.0 COG0243@1|root,COG0243@2|Bacteria,2G7V5@200795|Chloroflexi,375JH@32061|Chloroflexia 32061|Chloroflexia C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding DYD1_k127_6450029_25 1007103.AFHW01000008_gene6212 5.061e-05 52.0 29J6J@1|root,3063Z@2|Bacteria,1TZ59@1239|Firmicutes,4I8CC@91061|Bacilli,26ZJQ@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - DYD1_k127_6450029_16 903818.KI912269_gene527 1.429e-37 148.0 COG1247@1|root,COG1247@2|Bacteria 2|Bacteria M phosphinothricin N-acetyltransferase activity - - 2.3.1.183,2.3.1.82 ko:K03823,ko:K18816 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 br01600,ko00000,ko00001,ko01000,ko01504 - - - Acetyltransf_1,Methyltransf_25 DYD1_k127_6450029_11 1105367.CG50_05270 6.099e-65 226.0 COG1853@1|root,COG1853@2|Bacteria,1Q6RV@1224|Proteobacteria,2US3U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct DYD1_k127_6450029_22 1030157.AFMP01000040_gene1564 4.807e-11 68.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2UK4T@28211|Alphaproteobacteria,2K9ZZ@204457|Sphingomonadales 204457|Sphingomonadales E Glyoxalase-like domain - - - ko:K08234 - - - - ko00000 - - - - DYD1_k127_6450029_3 479434.Sthe_2909 3.022e-150 490.0 COG1012@1|root,COG1012@2|Bacteria,2G7YU@200795|Chloroflexi,27Y0H@189775|Thermomicrobia 189775|Thermomicrobia C Belongs to the aldehyde dehydrogenase family - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh DYD1_k127_6450029_15 1231391.AMZF01000094_gene98 2.601e-42 167.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_6460455_5 536227.CcarbDRAFT_1036 2.999e-05 51.0 COG0778@1|root,COG0778@2|Bacteria,1UZUV@1239|Firmicutes,24F6B@186801|Clostridia,36IIV@31979|Clostridiaceae 186801|Clostridia C PFAM Nitroreductase - - - - - - - - - - - - Nitroreductase,TM1586_NiRdase DYD1_k127_6460455_1 443143.GM18_0137 3.521e-173 557.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales 28221|Deltaproteobacteria J TIGRFAM ribonuclease, Rne Rng family cafA - 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD1_k127_6460455_3 290397.Adeh_1905 1.556e-81 276.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,437B2@68525|delta/epsilon subdivisions,2X2FR@28221|Deltaproteobacteria,2Z0QW@29|Myxococcales 28221|Deltaproteobacteria L HNH endonuclease - - - - - - - - - - - - HNH_5 DYD1_k127_6460455_0 443143.GM18_0861 7.625e-218 718.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales 28221|Deltaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge DYD1_k127_6460455_2 1121430.JMLG01000006_gene1788 6.704e-98 331.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,260N3@186807|Peptococcaceae 186801|Clostridia U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N DYD1_k127_6460455_4 595537.Varpa_4099 9.573e-08 56.0 COG0477@1|root,COG2814@2|Bacteria,1R8QG@1224|Proteobacteria,2VIBD@28216|Betaproteobacteria,4ABIS@80864|Comamonadaceae 28216|Betaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_6463065_2 269799.Gmet_3006 0.0001011 44.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2WIJ0@28221|Deltaproteobacteria,43U3N@69541|Desulfuromonadales 28221|Deltaproteobacteria L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase DYD1_k127_6463065_1 926569.ANT_07480 2.541e-13 80.0 COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi 200795|Chloroflexi P PFAM NMT1 THI5 like domain protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6463524_6 1034943.BN1094_03789 0.0005787 45.0 COG0235@1|root,COG0235@2|Bacteria,1RB5Z@1224|Proteobacteria 1224|Proteobacteria G class II Aldolase - GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 ko:K18613 ko00750,ko01120,map00750,map01120 - R03461 RC00569 ko00000,ko00001,ko01000 - - - Aldolase_II DYD1_k127_6463524_4 1267535.KB906767_gene4015 1.683e-12 76.0 COG5424@1|root,COG5424@2|Bacteria,3Y718@57723|Acidobacteria,2JKMM@204432|Acidobacteriia 204432|Acidobacteriia H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2 DYD1_k127_6463524_3 1134413.ANNK01000086_gene318 4.831e-64 231.0 COG0715@1|root,COG0715@2|Bacteria,1TXP3@1239|Firmicutes,4I6PJ@91061|Bacilli,1ZM9Z@1386|Bacillus 91061|Bacilli P NMT1/THI5 like - - - - - - - - - - - - NMT1 DYD1_k127_6463524_2 333138.LQ50_20025 4.42e-66 238.0 COG0715@1|root,COG0715@2|Bacteria,1TXP3@1239|Firmicutes,4I6PJ@91061|Bacilli,1ZM9Z@1386|Bacillus 91061|Bacilli P NMT1/THI5 like - - - - - - - - - - - - NMT1 DYD1_k127_6463524_5 631454.N177_2294 1.545e-09 69.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - - - - - - - - - - NMT1 DYD1_k127_6463524_1 1205680.CAKO01000038_gene1586 2.864e-111 368.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JRXA@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_6463524_0 706587.Desti_3265 2.274e-173 558.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,42M32@68525|delta/epsilon subdivisions,2WJA4@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD1_k127_6472896_3 945713.IALB_1946 0.0001122 49.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity - - - - - - - - - - - - CMD DYD1_k127_6472896_2 1173263.Syn7502_03004 1.68e-28 126.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_6472896_1 247490.KSU1_B0459 3.148e-77 266.0 COG0363@1|root,COG0363@2|Bacteria,2J0I5@203682|Planctomycetes 203682|Planctomycetes G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso DYD1_k127_6472896_0 671143.DAMO_0484 2.448e-85 289.0 COG0837@1|root,COG0837@2|Bacteria,2NR7Y@2323|unclassified Bacteria 2|Bacteria F Glucokinase glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase DYD1_k127_6474074_0 757424.Hsero_1419 2.481e-83 282.0 COG0500@1|root,COG2226@2|Bacteria,1RGQE@1224|Proteobacteria,2WF65@28216|Betaproteobacteria,476VR@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Hypothetical methyltransferase - - - - - - - - - - - - Methyltransf_11 DYD1_k127_6474074_5 83406.HDN1F_03130 2.564e-17 83.0 2C5EY@1|root,32YQJ@2|Bacteria,1N8K7@1224|Proteobacteria,1SDU6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4160) - - - - - - - - - - - - DUF4160 DYD1_k127_6474074_4 1173027.Mic7113_3915 4.406e-37 142.0 2DNRM@1|root,32YT2@2|Bacteria,1G8M2@1117|Cyanobacteria,1HC2R@1150|Oscillatoriales 1117|Cyanobacteria S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 DYD1_k127_6474074_1 595460.RRSWK_03017 1.492e-64 231.0 2A8GS@1|root,30XIR@2|Bacteria,2J2JC@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - DYD1_k127_6475673_5 1123321.KB905813_gene992 3.119e-80 275.0 COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria 201174|Actinobacteria J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA trmI GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 ko:K07442 - - - - ko00000,ko01000,ko03016 - - - GCD14,GCD14_N DYD1_k127_6475673_6 1121468.AUBR01000001_gene508 4.417e-80 287.0 COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,42FA6@68295|Thermoanaerobacterales 186801|Clostridia M PFAM Nucleotidyl transferase manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase DYD1_k127_6475673_8 309801.trd_1032 3.329e-48 190.0 COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,27Y1F@189775|Thermomicrobia 189775|Thermomicrobia J Responsible for synthesis of pseudouridine from uracil - - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD1_k127_6475673_0 251221.35211608 5.768e-159 510.0 COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria 1117|Cyanobacteria O Belongs to the deoxyhypusine synthase family - - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS DYD1_k127_6475673_7 671143.DAMO_2097 2.929e-68 242.0 COG2853@1|root,COG2853@2|Bacteria,2NRQC@2323|unclassified Bacteria 2|Bacteria M MlaA lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA DYD1_k127_6475673_1 398767.Glov_3341 5.221e-141 458.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,43U1Y@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein DYD1_k127_6475673_9 247490.KSU1_D0285 7.55e-33 134.0 2CA4A@1|root,32RQK@2|Bacteria,2J0BM@203682|Planctomycetes 203682|Planctomycetes S Domain of unknown function (DUF4416) - - - - - - - - - - - - DUF4416 DYD1_k127_6475673_4 290397.Adeh_2370 9.24e-81 276.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales 28221|Deltaproteobacteria L Uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD1_k127_6475673_2 706587.Desti_4373 1.866e-112 378.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MQRK@213462|Syntrophobacterales 28221|Deltaproteobacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD,SDH_sah DYD1_k127_6475673_3 880073.Calab_1132 8.718e-104 343.0 COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria 2|Bacteria O prohibitin homologues hflC - - - - - - - - - - - Band_7 DYD1_k127_6483177_0 1429046.RR21198_3290 3.023e-118 410.0 COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4FW1X@85025|Nocardiaceae 201174|Actinobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_6483177_1 582515.KR51_00021650 7.492e-103 341.0 COG0483@1|root,COG0483@2|Bacteria,1G09G@1117|Cyanobacteria 1117|Cyanobacteria G Inositol monophosphatase - - - - - - - - - - - - Inositol_P DYD1_k127_6483177_2 1232410.KI421412_gene26 5.154e-44 163.0 COG5637@1|root,COG5637@2|Bacteria,1MZY2@1224|Proteobacteria,430UG@68525|delta/epsilon subdivisions,2WVX4@28221|Deltaproteobacteria 28221|Deltaproteobacteria S polyketide cyclase - - - - - - - - - - - - - DYD1_k127_6483177_3 452662.SJA_C1-02370 5.802e-31 132.0 COG1024@1|root,COG1024@2|Bacteria,1MVB1@1224|Proteobacteria,2TVK3@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA ech - 4.1.2.41,4.2.1.101 ko:K18383 ko00360,ko01100,ko01110,map00360,map01100,map01110 - R05772,R05773 RC00307,RC01468,RC01828 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_6500014_3 1239962.C943_00462 2.512e-57 207.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes 976|Bacteroidetes S ATPase (AAA superfamily) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 DYD1_k127_6500014_2 189753.AXAS01000041_gene2534 2.327e-90 310.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6500014_1 189753.AXAS01000041_gene2534 1.107e-90 310.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6500014_0 189753.AXAS01000041_gene2534 6.398e-91 310.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6501416_2 861299.J421_4303 2.413e-47 173.0 COG3386@1|root,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity gnl GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD1_k127_6501416_4 700598.Niako_3128 1.21e-15 79.0 2EIK5@1|root,33CBF@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6501416_3 945713.IALB_1460 4.023e-16 85.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding - - - ko:K14061 - - - - ko00000 - - - Usp DYD1_k127_6501416_6 1192034.CAP_1189 0.0001499 45.0 COG0625@1|root,COG0625@2|Bacteria,1MX33@1224|Proteobacteria,439KN@68525|delta/epsilon subdivisions,2X4XG@28221|Deltaproteobacteria,2YZSS@29|Myxococcales 28221|Deltaproteobacteria O Glutathione S-transferase N-terminal domain - - - - - - - - - - - - GST_C_6,GST_N_4 DYD1_k127_6501416_5 329726.AM1_2608 2.939e-05 48.0 COG0625@1|root,COG0625@2|Bacteria,1G5VJ@1117|Cyanobacteria 1117|Cyanobacteria O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C_6,GST_N_4 DYD1_k127_6501416_0 1408445.JHXP01000014_gene1418 5.427e-155 506.0 COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RSC3@1236|Gammaproteobacteria,1JDAH@118969|Legionellales 118969|Legionellales C D-arabinono-1,4-lactone oxidase - - - - - - - - - - - - ALO,FAD_binding_4 DYD1_k127_6501416_1 1380394.JADL01000004_gene6065 2.128e-58 209.0 COG2227@1|root,COG2227@2|Bacteria,1QXTA@1224|Proteobacteria 1224|Proteobacteria H ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 DYD1_k127_6505400_1 1122604.JONR01000027_gene3068 1.497e-200 628.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1X3UT@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD1_k127_6505400_11 218140.BPSY_0029 1.964e-17 87.0 COG3576@1|root,COG3576@2|Bacteria,2IJK2@201174|Actinobacteria,4D0W8@85004|Bifidobacteriales 201174|Actinobacteria S Pfam:Pyridox_oxidase pdxH - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx DYD1_k127_6505400_5 1123288.SOV_1c06600 2.885e-59 209.0 COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,4H5AR@909932|Negativicutes 909932|Negativicutes C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 DYD1_k127_6505400_4 309801.trd_A0566 1.235e-66 239.0 COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia 189775|Thermomicrobia C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_6505400_12 196162.Noca_3967 1.717e-14 81.0 COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4DQ8Y@85009|Propionibacteriales 201174|Actinobacteria S Carbon monoxide dehydrogenase subunit G (CoxG) - - - - - - - - - - - - COXG DYD1_k127_6505400_9 522772.Dacet_2969 1.37e-35 147.0 COG0204@1|root,COG0204@2|Bacteria,2GGEH@200930|Deferribacteres 200930|Deferribacteres I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD1_k127_6505400_6 278957.ABEA03000126_gene3738 4.974e-57 208.0 COG3176@1|root,COG3176@2|Bacteria,46Y6I@74201|Verrucomicrobia,3K90P@414999|Opitutae 414999|Opitutae S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_5 DYD1_k127_6505400_7 1379698.RBG1_1C00001G0904 4.693e-56 204.0 COG1024@1|root,COG1024@2|Bacteria 2|Bacteria I Enoyl-CoA hydratase bamR - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD1_k127_6505400_10 1123261.AXDW01000011_gene538 5.836e-18 93.0 COG2885@1|root,COG2885@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the ompA family mopB - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 DYD1_k127_6505400_8 797304.Natgr_1492 2.501e-48 180.0 COG0293@1|root,COG3269@1|root,arCOG00079@2157|Archaea,arCOG01641@2157|Archaea,2XT12@28890|Euryarchaeota,23T6V@183963|Halobacteria 183963|Halobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit rrmJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ,TRAM DYD1_k127_6505400_3 204669.Acid345_0343 1.537e-108 360.0 COG1085@1|root,COG1085@2|Bacteria,3Y41K@57723|Acidobacteria,2JMKJ@204432|Acidobacteriia 204432|Acidobacteriia C Domain of unknown function (DUF4921) - - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C DYD1_k127_6505400_0 1232410.KI421422_gene2063 8.546e-230 727.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,43S1W@69541|Desulfuromonadales 28221|Deltaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iAF987.Gmet_1487 GATase_6,SIS DYD1_k127_6505400_2 338966.Ppro_0501 1.167e-126 420.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,43SUA@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase DYD1_k127_6510565_3 314278.NB231_10223 7.926e-98 331.0 COG1752@1|root,COG1752@2|Bacteria 2|Bacteria M Esterase of the alpha-beta hydrolase superfamily plpD - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,POTRA,Patatin DYD1_k127_6510565_7 1210884.HG799464_gene10800 7.687e-22 106.0 COG2267@1|root,COG2267@2|Bacteria,2IZH7@203682|Planctomycetes 203682|Planctomycetes I Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 DYD1_k127_6510565_1 572477.Alvin_2816 2.43e-118 400.0 COG0189@1|root,COG0189@2|Bacteria,1R0ZJ@1224|Proteobacteria,1T4SZ@1236|Gammaproteobacteria,1WXS5@135613|Chromatiales 135613|Chromatiales HJ PFAM GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 DYD1_k127_6510565_5 575540.Isop_0256 6.439e-67 242.0 COG4948@1|root,COG4948@2|Bacteria,2IX42@203682|Planctomycetes 203682|Planctomycetes M Mandelate racemase muconate lactonizing enzyme - - 5.1.1.20,5.5.1.1 ko:K01856,ko:K19802 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R05300,R05390,R06989,R08116,R09229,R10938 RC00903,RC01038,RC01108,RC01321,RC01356,RC03309 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N DYD1_k127_6510565_6 575540.Isop_0255 3.92e-38 155.0 COG2267@1|root,COG2267@2|Bacteria,2IZH7@203682|Planctomycetes 203682|Planctomycetes I Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 DYD1_k127_6510565_4 314278.NB231_10218 2.206e-84 288.0 COG0455@1|root,COG0455@2|Bacteria,1RBXA@1224|Proteobacteria,1SNA0@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Cellulose biosynthesis protein BcsQ - - - - - - - - - - - - CbiA DYD1_k127_6510565_0 1267535.KB906767_gene447 8.692e-133 446.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia 204432|Acidobacteriia T Tetratricopeptide repeat - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_12 DYD1_k127_6510565_8 1122963.AUHB01000007_gene3603 3.861e-05 55.0 COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,2TTCR@28211|Alphaproteobacteria,36XZ3@31993|Methylocystaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase of unknown function (DUF900) - - - - - - - - - - - - DUF900 DYD1_k127_6510565_2 1429916.X566_14890 1.005e-116 378.0 COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria,3K3FV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase DYD1_k127_6510569_3 244447.XP_008310202.1 0.0002909 54.0 COG5184@1|root,2QWB5@2759|Eukaryota,38G86@33154|Opisthokonta,3BBSM@33208|Metazoa,3CSQF@33213|Bilateria,487A8@7711|Chordata,491BP@7742|Vertebrata,4A0UI@7898|Actinopterygii 33208|Metazoa DZ Early endosome antigen 1 EEA1 GO:0003674,GO:0005488,GO:0005515,GO:0005516,GO:0005543,GO:0005545,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0005969,GO:0006810,GO:0006897,GO:0006906,GO:0006996,GO:0008150,GO:0008270,GO:0008289,GO:0009987,GO:0010008,GO:0012505,GO:0016020,GO:0016032,GO:0016043,GO:0016050,GO:0016189,GO:0016192,GO:0016197,GO:0016482,GO:0019058,GO:0019079,GO:0019897,GO:0019898,GO:0030139,GO:0030424,GO:0030742,GO:0031090,GO:0031410,GO:0031901,GO:0031982,GO:0032266,GO:0032991,GO:0033267,GO:0035091,GO:0039694,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0044308,GO:0044309,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045022,GO:0046872,GO:0046907,GO:0046914,GO:0046983,GO:0048284,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0055037,GO:0061024,GO:0061025,GO:0071840,GO:0071944,GO:0090174,GO:0097458,GO:0097708,GO:0098588,GO:0098657,GO:0098805,GO:0098927,GO:0099003,GO:0099504,GO:0099532,GO:0120025,GO:0120038,GO:1901981,GO:1902494,GO:1990234 - ko:K12478 ko04144,ko04145,ko05152,map04144,map04145,map05152 - - - ko00000,ko00001,ko04131 - - - FYVE DYD1_k127_6510569_1 935548.KI912159_gene5302 1.122e-30 134.0 COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2TSHF@28211|Alphaproteobacteria,43H6C@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6510569_0 351607.Acel_1632 2.413e-42 165.0 COG3665@1|root,COG3665@2|Bacteria,2GKI6@201174|Actinobacteria,4EWF7@85013|Frankiales 201174|Actinobacteria S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 DYD1_k127_6510569_2 443152.MDG893_15295 2.696e-17 93.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_651186_1 1121271.AUCM01000002_gene3965 7.061e-45 169.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2U7CZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M (Lipo)protein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA DYD1_k127_651186_3 1121403.AUCV01000047_gene1026 4.296e-16 83.0 COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria 1224|Proteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 DYD1_k127_651186_2 1160137.KB907307_gene87 2.35e-21 106.0 COG0715@1|root,COG0715@2|Bacteria,2HHNY@201174|Actinobacteria,4FZGF@85025|Nocardiaceae 201174|Actinobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_651186_0 189753.AXAS01000041_gene2534 2.817e-86 297.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_651186_4 68170.KL590490_gene1015 9.958e-11 71.0 COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria,4E4EM@85010|Pseudonocardiales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - DUF4440,Glyoxalase DYD1_k127_6512436_6 1128421.JAGA01000002_gene633 1.045e-65 233.0 COG0179@1|root,COG0179@2|Bacteria,2NP4G@2323|unclassified Bacteria 2|Bacteria Q Fumarylacetoacetate (FAA) hydrolase family fahA2 - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase DYD1_k127_6512436_1 1100720.ALKN01000040_gene2251 6.722e-141 458.0 COG2267@1|root,COG2267@2|Bacteria,1MV7P@1224|Proteobacteria,2VPTY@28216|Betaproteobacteria,4AGS7@80864|Comamonadaceae 28216|Betaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 DYD1_k127_6512436_8 1005048.CFU_0645 2.519e-49 182.0 COG4106@1|root,COG4106@2|Bacteria,1QUZE@1224|Proteobacteria,2VSHF@28216|Betaproteobacteria,474Y9@75682|Oxalobacteraceae 28216|Betaproteobacteria S Thiopurine S-methyltransferase (TPMT) - - - - - - - - - - - - TPMT DYD1_k127_6512436_11 743719.PaelaDRAFT_3269 9.916e-20 96.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,26YJV@186822|Paenibacillaceae 91061|Bacilli J endoribonuclease L-PSP yhaR - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP DYD1_k127_6512436_10 485913.Krac_11396 2.937e-35 148.0 COG2141@1|root,COG2141@2|Bacteria 2|Bacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_6512436_7 392499.Swit_4311 3.305e-61 222.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,2K5XQ@204457|Sphingomonadales 204457|Sphingomonadales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.16 ko:K05713,ko:K15755 ko00360,ko00621,ko01100,ko01120,ko01220,map00360,map00621,map01100,map01120,map01220 M00544,M00545 R04376,R05415,R06788 RC01140,RC01306,RC01364 br01602,ko00000,ko00001,ko00002,ko01000 - - - LigB DYD1_k127_6512436_12 1205680.CAKO01000002_gene3085 1.891e-15 80.0 2DPNC@1|root,32UMG@2|Bacteria,1N0XW@1224|Proteobacteria,2UVTT@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - - - - - - - - - - LigA DYD1_k127_6512436_5 314271.RB2654_02824 8.757e-96 325.0 COG1073@1|root,COG1073@2|Bacteria,1N5CG@1224|Proteobacteria 1224|Proteobacteria S Belongs to the UPF0255 family frsA GO:0003674,GO:0003824,GO:0005575,GO:0006109,GO:0006629,GO:0008150,GO:0008152,GO:0009894,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0019222,GO:0043470,GO:0044238,GO:0050789,GO:0065007,GO:0071704,GO:0080090 - ko:K11750 - - - - ko00000,ko01000 - - - DUF1100 DYD1_k127_6512436_4 398767.Glov_0508 2.036e-109 362.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,43UKB@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_1162 THF_DHG_CYH,THF_DHG_CYH_C DYD1_k127_6512436_3 349161.Dred_0720 6.013e-123 404.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,261AX@186807|Peptococcaceae 186801|Clostridia E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C DYD1_k127_6512436_9 986075.CathTA2_3037 8.083e-46 169.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli 91061|Bacilli E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate gcvH GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H DYD1_k127_6512436_2 671143.DAMO_0706 4.609e-129 426.0 COG0403@1|root,COG0403@2|Bacteria,2NNP1@2323|unclassified Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P DYD1_k127_6512436_0 1499967.BAYZ01000136_gene58 8.38e-197 625.0 COG1003@1|root,COG1003@2|Bacteria,2NNSG@2323|unclassified Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - Aminotran_5,GDC-P DYD1_k127_6512436_13 1121937.AUHJ01000010_gene1620 4.319e-11 73.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,465SW@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0810 Periplasmic protein TonB, links inner and outer membranes tonB3 - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD1_k127_6512436_14 667014.Thein_0480 3.111e-08 57.0 COG1826@1|root,COG1826@2|Bacteria,2GI1R@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD1_k127_651493_6 290397.Adeh_1221 2.791e-63 234.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales 28221|Deltaproteobacteria S Putative glutamine amidotransferase - - - - - - - - - - - - GATase1_like DYD1_k127_651493_5 247490.KSU1_C0323 4.77e-65 231.0 COG1657@1|root,COG1657@2|Bacteria 2|Bacteria I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - A2M_comp,DUF4159,Prenyltrans DYD1_k127_651493_4 575540.Isop_3542 3.718e-77 287.0 COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes 203682|Planctomycetes G Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA,VWA_2 DYD1_k127_651493_3 247490.KSU1_C0185 4.423e-88 300.0 COG1721@1|root,COG1721@2|Bacteria,2IY2F@203682|Planctomycetes 203682|Planctomycetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 DYD1_k127_651493_0 247490.KSU1_C0183 1.33e-133 434.0 COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes 203682|Planctomycetes S associated with various cellular activities - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD1_k127_651493_2 247490.KSU1_D0349 1.537e-94 329.0 COG0457@1|root,COG0457@2|Bacteria,2IWTH@203682|Planctomycetes 203682|Planctomycetes S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - Peptidase_MA_2,TPR_16,TPR_19 DYD1_k127_651493_7 378806.STAUR_7399 5.559e-59 234.0 COG1196@1|root,COG1196@2|Bacteria,1QX9X@1224|Proteobacteria,43018@68525|delta/epsilon subdivisions,2WVD9@28221|Deltaproteobacteria,2YW2N@29|Myxococcales 28221|Deltaproteobacteria D Domain of unknown function (DUF4175) - - - - - - - - - - - - DUF4175 DYD1_k127_651493_1 333138.LQ50_20170 3.228e-123 413.0 COG4819@1|root,COG4819@2|Bacteria,1TQ6T@1239|Firmicutes,4HAEM@91061|Bacilli,1ZDKX@1386|Bacillus 91061|Bacilli E Ethanolamine utilisation protein EutA eutA - - ko:K04019 ko00564,ko01100,map00564,map01100 - R00749 RC00370 ko00000,ko00001 - - - EutA DYD1_k127_6518344_9 1365176.N186_02495 2.378e-11 66.0 COG2442@1|root,arCOG07520@2157|Archaea,2XRG3@28889|Crenarchaeota 28889|Crenarchaeota S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 DYD1_k127_6518344_1 1385519.N801_18235 3.88e-98 331.0 COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4FJQG@85021|Intrasporangiaceae 201174|Actinobacteria C Luciferase-like monooxygenase - - 1.5.98.2 ko:K00320,ko:K14728 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R04464 RC01607 ko00000,ko00001,ko00002,ko01000 - - - Bac_luciferase DYD1_k127_6518344_0 1298864.AUEQ01000002_gene6173 8.701e-125 412.0 COG0402@1|root,COG0402@2|Bacteria,2IBR8@201174|Actinobacteria,2372F@1762|Mycobacteriaceae 201174|Actinobacteria F Amidohydrolase family - - 3.5.2.18 ko:K15358 ko00760,ko01120,map00760,map01120 - R07984 RC01933 ko00000,ko00001,ko01000 - - - Amidohydro_1 DYD1_k127_6518344_3 247490.KSU1_D0785 4.876e-55 212.0 COG1108@1|root,COG1108@2|Bacteria 2|Bacteria P ABC-type Mn2 Zn2 transport systems permease components znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 DYD1_k127_6518344_4 1120944.JONS01000013_gene245 4.703e-43 166.0 COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,4D4QH@85005|Actinomycetales 201174|Actinobacteria P ABC transporter, ATP-binding protein yfeB - - ko:K02074,ko:K09820,ko:K11603,ko:K11710 ko02010,ko02020,map02010,map02020 M00243,M00244,M00316,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.1 - - ABC_tran DYD1_k127_6518344_2 247490.KSU1_D0783 4.195e-68 244.0 COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes 203682|Planctomycetes P Zinc-uptake complex component A periplasmic - - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA DYD1_k127_6518344_5 404589.Anae109_1534 1.291e-33 145.0 COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria,2YYH9@29|Myxococcales 28221|Deltaproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - DYD1_k127_6518344_7 204669.Acid345_4527 8.157e-32 132.0 COG1595@1|root,COG1595@2|Bacteria,3Y4CH@57723|Acidobacteria,2JJ6R@204432|Acidobacteriia 204432|Acidobacteriia K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD1_k127_6518344_8 1121918.ARWE01000001_gene1968 3.274e-17 89.0 2DQD7@1|root,3361P@2|Bacteria,1NAB8@1224|Proteobacteria,42WKD@68525|delta/epsilon subdivisions,2WRQT@28221|Deltaproteobacteria,43SQJ@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF3106) - - - - - - - - - - - - DUF3106 DYD1_k127_6518344_6 316274.Haur_1682 2.998e-33 134.0 COG5267@1|root,COG5267@2|Bacteria,2G7Q0@200795|Chloroflexi,376N0@32061|Chloroflexia 2|Bacteria S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 DYD1_k127_6529377_2 1121423.JONT01000007_gene589 1.413e-49 180.0 COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,2621A@186807|Peptococcaceae 186801|Clostridia E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II DYD1_k127_6529377_1 1121430.JMLG01000021_gene1379 7.643e-111 368.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae 186801|Clostridia E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase DYD1_k127_6529377_3 1392502.JNIO01000008_gene2346 4.769e-37 145.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4H4XC@909932|Negativicutes 909932|Negativicutes E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI DYD1_k127_6529377_0 269799.Gmet_0976 1.879e-133 434.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,43U6V@69541|Desulfuromonadales 28221|Deltaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0976 Chorismate_synt DYD1_k127_6529641_2 1267535.KB906767_gene3245 1.297e-107 359.0 COG4307@1|root,COG4307@2|Bacteria 2|Bacteria T Protein conserved in bacteria - - - - - - - - - - - - Peptidase_Mx,zinc-ribbon_6 DYD1_k127_6529641_3 452637.Oter_2162 1.749e-106 355.0 COG1181@1|root,COG1181@2|Bacteria 2|Bacteria F Belongs to the D-alanine--D-alanine ligase family ddlB1 - 6.3.2.4,6.3.5.5 ko:K01921,ko:K01955 ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502 M00051 R00256,R00575,R01150,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000,ko01011 - - - Dala_Dala_lig_C DYD1_k127_6529641_5 671065.MetMK1DRAFT_00016440 2.311e-40 158.0 COG3396@1|root,arCOG04786@2157|Archaea 2157|Archaea S Phenylacetate-CoA oxygenase paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC DYD1_k127_6529641_1 640081.Dsui_0784 1.05e-210 666.0 COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2VMMF@28216|Betaproteobacteria,2KV9B@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF1343) - - - - - - - - - - - - DUF1343 DYD1_k127_6529641_6 76114.ebA3238 1.158e-38 151.0 2C0PI@1|root,32VVI@2|Bacteria,1N1H7@1224|Proteobacteria,2VUDK@28216|Betaproteobacteria,2KX1H@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD1_k127_6529641_0 713586.KB900536_gene376 2.014e-264 830.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM DYD1_k127_6529641_4 396588.Tgr7_1470 8.413e-106 352.0 COG2358@1|root,COG2358@2|Bacteria 2|Bacteria G TRAP transporter, solute receptor (TAXI family MA20_27285 - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD1_k127_6531499_1 1379698.RBG1_1C00001G0780 7.478e-99 327.0 COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria 2|Bacteria C Cytochrome b(N-terminal)/b6/petB petB - - ko:K00410,ko:K00412,ko:K02635,ko:K02637 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B DYD1_k127_6531499_3 671143.DAMO_0820 2.604e-54 196.0 COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria 2|Bacteria C Rieske [2Fe-2S] domain petA - 1.10.2.2,1.10.9.1 ko:K00411,ko:K02636,ko:K03886 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - iAF987.Gmet_1922 CytB6-F_Fe-S,Rieske,UCR_Fe-S_N DYD1_k127_6531499_0 671143.DAMO_0822 7.856e-125 413.0 COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria 2|Bacteria C Cytochrome c554 and c-prime - - - ko:K03620 ko02020,map02020 - - - ko00000,ko00001 - - - Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB DYD1_k127_6531499_2 1379698.RBG1_1C00001G0858 1.939e-80 283.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C DYD1_k127_6531499_4 1330700.JQNC01000003_gene911 1.539e-22 98.0 COG3258@1|root,COG3258@2|Bacteria,1WMNM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD1_k127_6549773_33 483219.LILAB_07670 1.495e-39 152.0 COG1522@1|root,COG1522@2|Bacteria,1N0DP@1224|Proteobacteria,42W6I@68525|delta/epsilon subdivisions,2WSF8@28221|Deltaproteobacteria,2YW31@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix ASNC type - - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type DYD1_k127_6549773_0 398512.JQKC01000033_gene5010 0.0 2184.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae 186801|Clostridia E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase DYD1_k127_6549773_2 398512.JQKC01000033_gene5009 4.688e-249 775.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae 186801|Clostridia C glutamate synthase gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 DYD1_k127_6549773_46 686340.Metal_0931 0.0004279 51.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XFQY@135618|Methylococcales 135618|Methylococcales O Subtilase family - - - - - - - - - - - - Peptidase_S8 DYD1_k127_6549773_12 935840.JAEQ01000002_gene3285 1.308e-121 398.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,43HMK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Glutathione S-transferase yqjG GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 DYD1_k127_6549773_45 1089544.KB912942_gene6161 5.403e-05 47.0 COG3871@1|root,COG3871@2|Bacteria,2I2S9@201174|Actinobacteria,4E3EK@85010|Pseudonocardiales 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx DYD1_k127_6549773_38 710686.Mycsm_04484 1.719e-25 117.0 COG2084@1|root,COG2084@2|Bacteria,2GP2C@201174|Actinobacteria,233JB@1762|Mycobacteriaceae 201174|Actinobacteria I Dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 DYD1_k127_6549773_43 1267535.KB906767_gene2743 9.955e-10 68.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,PG_binding_1 DYD1_k127_6549773_14 1205680.CAKO01000007_gene4412 1.468e-110 367.0 COG2141@1|root,COG2141@2|Bacteria,1NX0H@1224|Proteobacteria,2U42F@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_6549773_9 479432.Sros_3818 2.074e-144 473.0 COG0680@1|root,COG0680@2|Bacteria,2GKMU@201174|Actinobacteria,4EHP1@85012|Streptosporangiales 201174|Actinobacteria C Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - - - - - - - - - - - DYD1_k127_6549773_30 882086.SacxiDRAFT_1190 2.952e-50 184.0 COG0680@1|root,COG0680@2|Bacteria,2GN48@201174|Actinobacteria,4E5CZ@85010|Pseudonocardiales 201174|Actinobacteria C TIGRFAM hydrogenase maturation protease hupD1 - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI DYD1_k127_6549773_37 479432.Sros_3821 4.653e-27 113.0 COG0375@1|root,COG0375@2|Bacteria,2I146@201174|Actinobacteria,4EKU8@85012|Streptosporangiales 201174|Actinobacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - ko:K04651 - - - - ko00000,ko03110 - - - HypA DYD1_k127_6549773_42 1122611.KB903943_gene1574 6.756e-10 61.0 COG0298@1|root,COG0298@2|Bacteria,2IRJ9@201174|Actinobacteria,4EQ40@85012|Streptosporangiales 201174|Actinobacteria O HupF/HypC family hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC DYD1_k127_6549773_1 1382306.JNIM01000001_gene189 9.649e-278 873.0 COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi 200795|Chloroflexi O Belongs to the carbamoyltransferase HypF family hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF DYD1_k127_6549773_36 234267.Acid_6551 3.193e-30 121.0 COG0298@1|root,COG0298@2|Bacteria,3Y5NM@57723|Acidobacteria 57723|Acidobacteria O PFAM hydrogenase expression formation protein (HUPF HYPC) - - - ko:K04653 - - - - ko00000 - - - HupF_HypC DYD1_k127_6549773_4 682795.AciX8_4211 2.071e-190 599.0 COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria,2JIK0@204432|Acidobacteriia 204432|Acidobacteriia O Hydrogenase formation hypA family - - - ko:K04654 - - - - ko00000 - - - HypD DYD1_k127_6549773_21 234267.Acid_6553 4.95e-74 255.0 COG0279@1|root,COG0279@2|Bacteria,3Y4UX@57723|Acidobacteria 57723|Acidobacteria G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 DYD1_k127_6549773_8 682795.AciX8_4212 1.388e-155 499.0 COG0309@1|root,COG0309@2|Bacteria,3Y3UH@57723|Acidobacteria,2JK96@204432|Acidobacteriia 204432|Acidobacteriia O AIR synthase related protein, C-terminal domain - - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C DYD1_k127_6549773_29 395963.Bind_0995 3.942e-52 190.0 COG0346@1|root,COG0346@2|Bacteria,1RIUN@1224|Proteobacteria,2U9CD@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD1_k127_6549773_39 941449.dsx2_3250 2.441e-22 101.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales 28221|Deltaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - CHASE5,HATPase_c,HisKA,PAS,PAS_4,Response_reg DYD1_k127_6549773_18 264198.Reut_C6311 2.048e-85 293.0 COG0715@1|root,COG0715@2|Bacteria,1NS24@1224|Proteobacteria 1224|Proteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - NMT1_2 DYD1_k127_6549773_22 1123392.AQWL01000002_gene1981 2.163e-69 241.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,1KSU5@119069|Hydrogenophilales 119069|Hydrogenophilales C Ferric reductase like transmembrane component - - - - - - - - - - - - Ferric_reduct DYD1_k127_6549773_10 857087.Metme_0178 1.094e-134 437.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,1XG5Y@135618|Methylococcales 135618|Methylococcales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb DYD1_k127_6549773_27 289376.THEYE_A0140 8.759e-55 201.0 COG0744@1|root,COG0744@2|Bacteria,3J127@40117|Nitrospirae 40117|Nitrospirae M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly DYD1_k127_6549773_19 1254432.SCE1572_23620 2.804e-79 277.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales 28221|Deltaproteobacteria L A G-specific mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 DYD1_k127_6549773_26 1007105.PT7_2847 1.429e-59 223.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,3T1UV@506|Alcaligenaceae 28216|Betaproteobacteria EGP Permeases of the major facilitator superfamily yajR - - - - - - - - - - - MFS_1,Sugar_tr DYD1_k127_6549773_15 330214.NIDE3131 2.276e-107 356.0 COG0668@1|root,COG0668@2|Bacteria,3J0YK@40117|Nitrospirae 40117|Nitrospirae M Mechanosensitive ion channel - - - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel DYD1_k127_6549773_24 338963.Pcar_2900 1.203e-65 232.0 COG0084@1|root,COG0084@2|Bacteria,1R450@1224|Proteobacteria,42WEC@68525|delta/epsilon subdivisions 1224|Proteobacteria L TatD related DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase DYD1_k127_6549773_44 292459.STH2788 1.229e-09 68.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity cpeZ - - ko:K05384,ko:K05386 ko00196,ko01100,map00196,map01100 - - - ko00000,ko00001,ko00194 - - - HEAT_2 DYD1_k127_6549773_11 671143.DAMO_1573 1.339e-122 405.0 COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria 2|Bacteria E Metallopeptidase family M24 pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Creatinase_N,Peptidase_M24 DYD1_k127_6549773_3 1242864.D187_004712 1.168e-231 729.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2YU6I@29|Myxococcales 28221|Deltaproteobacteria I Carboxyl transferase domain pccB - 2.1.3.1,2.1.3.15,6.4.1.3 ko:K01966,ko:K17489 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R00353,R01859 RC00040,RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD1_k127_6549773_5 944480.ATUV01000001_gene1116 5.406e-180 576.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2M6KR@213113|Desulfurellales 28221|Deltaproteobacteria I Biotin carboxylase C-terminal domain pccA - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD1_k127_6549773_35 1297742.A176_03478 7.76e-33 138.0 COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2YVN7@29|Myxococcales 28221|Deltaproteobacteria I Biotin-requiring enzyme - - - - - - - - - - - - Biotin_lipoyl DYD1_k127_6549773_20 1519464.HY22_09305 3.48e-78 265.0 COG1945@1|root,COG1945@2|Bacteria,1FDKS@1090|Chlorobi 1090|Chlorobi E Belongs to the PdaD family pdaD - 4.1.1.19 ko:K02626 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PvlArgDC DYD1_k127_6549773_28 1125863.JAFN01000001_gene1876 8.938e-54 198.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC DYD1_k127_6549773_41 1232410.KI421420_gene3180 1.425e-18 88.0 COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,43SSF@69541|Desulfuromonadales 28221|Deltaproteobacteria U mttA/Hcf106 family tatB - - ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD1_k127_6549773_16 706587.Desti_2766 1.683e-95 323.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MRB2@213462|Syntrophobacterales 28221|Deltaproteobacteria BQ Histone deacetylase domain - - - - - - - - - - - - Hist_deacetyl DYD1_k127_6549773_6 269799.Gmet_1603 2.669e-176 562.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,43TSR@69541|Desulfuromonadales 28221|Deltaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD1_k127_6549773_13 316067.Geob_2612 3.99e-112 370.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43S1E@69541|Desulfuromonadales 28221|Deltaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH-2 - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD1_k127_6549773_7 880072.Desac_2700 3.789e-160 516.0 COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2MQV1@213462|Syntrophobacterales 28221|Deltaproteobacteria F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase,QRPTase_C DYD1_k127_6549773_34 671065.MetMK1DRAFT_00016440 2.065e-34 142.0 COG3396@1|root,arCOG04786@2157|Archaea 2157|Archaea S Phenylacetate-CoA oxygenase paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC DYD1_k127_6549773_23 485913.Krac_11234 5.349e-69 243.0 COG2086@1|root,COG2086@2|Bacteria,2G6YY@200795|Chloroflexi 200795|Chloroflexi C PFAM Electron transfer flavoprotein alpha beta-subunit - - - ko:K03521 - - - - ko00000 - - - ETF DYD1_k127_6549773_17 1382306.JNIM01000001_gene2733 4.286e-92 312.0 COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi 200795|Chloroflexi C electron transfer flavoprotein, alpha subunit - - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha DYD1_k127_6549773_32 671143.DAMO_2920 4.965e-44 168.0 2DRSH@1|root,33CVS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6549773_25 247490.KSU1_C0672 2.967e-65 227.0 COG4096@1|root,COG4096@2|Bacteria,2IXTV@203682|Planctomycetes 203682|Planctomycetes L EcoEI R protein C-terminal - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoEI_R_C,Helicase_C,ResIII DYD1_k127_6549773_31 622637.KE124774_gene2618 2.406e-47 174.0 COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,2TUKC@28211|Alphaproteobacteria,36YDM@31993|Methylocystaceae 28211|Alphaproteobacteria L EcoEI R protein C-terminal - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF4145,EcoEI_R_C,HSDR_N_2,Helicase_C,ResIII DYD1_k127_655087_7 1168059.KB899087_gene1280 8.232e-10 61.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3F11J@335928|Xanthobacteraceae 28211|Alphaproteobacteria J Amidase - - - - - - - - - - - - Amidase DYD1_k127_655087_4 1460634.JCM19037_1983 3.333e-58 214.0 COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli 91061|Bacilli S metal-dependent hydrolase of the TIM-barrel fold - - 4.1.1.45,4.1.1.52 ko:K03392,ko:K22213 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD1_k127_655087_6 1122604.JONR01000001_gene1778 5.165e-14 74.0 2C1EV@1|root,33RW1@2|Bacteria,1R3AA@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_655087_3 246194.CHY_1273 7.85e-67 238.0 COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,42G3H@68295|Thermoanaerobacterales 186801|Clostridia K Transcriptional regulator IclR - - - - - - - - - - - - HTH_IclR,IclR DYD1_k127_655087_2 574375.BAGA_18080 7.596e-83 284.0 COG3971@1|root,COG3971@2|Bacteria,1TQVG@1239|Firmicutes,4HBMC@91061|Bacilli,1ZC05@1386|Bacillus 91061|Bacilli Q 2-keto-4-pentenoate hydratase - - 4.2.1.80 ko:K02554 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R02601,R04781 RC00750,RC01213 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase DYD1_k127_655087_1 1234664.AMRO01000077_gene3348 7.72e-115 377.0 COG4569@1|root,COG4569@2|Bacteria,1TQJS@1239|Firmicutes,4HCRZ@91061|Bacilli,1WG8K@129337|Geobacillus 91061|Bacilli Q Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds mhpF - 1.2.1.10 ko:K04073 ko00360,ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00360,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220 M00545,M00569 R00228,R01172 RC00004,RC00184,RC01195 br01602,ko00000,ko00001,ko00002,ko01000 - - - AcetDehyd-dimer,Semialdhyde_dh DYD1_k127_655087_0 264732.Moth_1775 4.799e-132 434.0 COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,42EWU@68295|Thermoanaerobacterales 186801|Clostridia E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds mhpE - 4.1.3.39 ko:K01666 ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220 M00545,M00569 R00750 RC00307,RC00371 br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like DYD1_k127_655087_5 247156.NFA_4730 8.799e-35 140.0 COG2267@1|root,COG2267@2|Bacteria,2H6J4@201174|Actinobacteria,4FWMQ@85025|Nocardiaceae 201174|Actinobacteria I Serine aminopeptidase, S33 hsaD GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016822,GO:0016823,GO:0030312,GO:0034820,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 3.1.1.24,3.7.1.17 ko:K01055,ko:K16050 ko00362,ko00984,ko01100,ko01120,ko01220,map00362,map00984,map01100,map01120,map01220 M00568 R02991,R09883 RC00825,RC02018,RC02740 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 DYD1_k127_6551985_4 1177928.TH2_19954 1.626e-07 53.0 2DVDD@1|root,32UZ7@2|Bacteria,1NGRW@1224|Proteobacteria,2UC61@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2933) - - - - - - - - - - - - DUF2933 DYD1_k127_6551985_2 1282876.BAOK01000001_gene2741 3.123e-47 172.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,2UEDS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 DYD1_k127_6551985_0 644966.Tmar_1561 0.0 1024.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WCCN@538999|Clostridiales incertae sedis 186801|Clostridia P ATPase, P-type (transporting), HAD superfamily, subfamily IC copA - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase DYD1_k127_6551985_3 671143.DAMO_0039 7.323e-15 76.0 COG3350@1|root,COG3350@2|Bacteria 2|Bacteria T monooxygenase activity - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - DJ-1_PfpI,YHS DYD1_k127_6551985_1 331113.SNE_B24410 5.776e-125 405.0 COG0058@1|root,COG0058@2|Bacteria,2JFEH@204428|Chlamydiae 204428|Chlamydiae G Carbohydrate phosphorylase glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase DYD1_k127_65655_3 682795.AciX8_1821 0.0003504 43.0 28ZM0@1|root,2ZMCA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_65655_1 933262.AXAM01000115_gene1527 8.504e-74 257.0 28IWY@1|root,2Z8V1@2|Bacteria,1R9PZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_65655_2 1323361.JPOC01000048_gene399 1.026e-09 64.0 2CJXB@1|root,2ZIFC@2|Bacteria,2H9YF@201174|Actinobacteria,4G6W7@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_65655_0 331113.SNE_A19410 3.6e-131 428.0 COG1373@1|root,COG1373@2|Bacteria 2|Bacteria V ATPase (AAA superfamily - - - - - - - - - - - - AAA_14,DUF4143 DYD1_k127_6575131_3 1449350.OCH239_12000 4.365e-12 66.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2TTPX@28211|Alphaproteobacteria,4KMEG@93682|Roseivivax 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_6575131_1 550540.Fbal_3582 2.732e-54 197.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_6575131_2 1392501.JIAC01000001_gene1552 3.897e-19 96.0 COG3381@1|root,COG3381@2|Bacteria,1VDIH@1239|Firmicutes,4H5UW@909932|Negativicutes 909932|Negativicutes S Nitrate reductase delta subunit - - - - - - - - - - - - Nitrate_red_del DYD1_k127_6575131_0 744980.TRICHSKD4_3999 8.278e-56 218.0 COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2TWJ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Iron-sulfur cluster-binding protein - - - - - - - - - - - - Fer4,Fer4_7 DYD1_k127_6581596_0 547144.HydHO_1416 4.797e-179 567.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,2G4N5@200783|Aquificae 200783|Aquificae CI RnfC Barrel sandwich hybrid domain - - 6.4.1.7 ko:K20140 - - - - ko00000,ko01000 - - - Biotin_lipoyl,HMGL-like,PYC_OADA DYD1_k127_6581596_1 290397.Adeh_3929 1.599e-124 405.0 COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales 28221|Deltaproteobacteria L Belongs to the FPG family - - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD1_k127_6581596_2 1306990.BARG01000030_gene3384 3.674e-68 238.0 COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria 201174|Actinobacteria Q Pfam Cupin - - 1.13.11.38,1.13.11.4 ko:K00450,ko:K11948 ko00350,ko00624,ko01100,ko01120,map00350,map00624,map01100,map01120 - R02656,R07657 RC00764,RC00937 ko00000,ko00001,ko01000 - - - Cupin_2 DYD1_k127_6596796_0 1134413.ANNK01000114_gene1920 5.808e-77 271.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD1_k127_6596796_1 1173028.ANKO01000044_gene779 6.485e-76 270.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1HAHP@1150|Oscillatoriales 1117|Cyanobacteria S metal-dependent hydrolase of the TIM-barrel fold - - - - - - - - - - - - Amidohydro_2 DYD1_k127_6596796_2 1049564.TevJSym_ap00120 3.839e-39 148.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,1J6NS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function, DUF - - - - - - - - - - - - DUF411 DYD1_k127_6596796_4 1303518.CCALI_01929 4.049e-07 60.0 COG5424@1|root,COG5424@2|Bacteria 2|Bacteria H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ CP_1111 GO:0005575,GO:0005576 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2,TENA_THI-4 DYD1_k127_6596796_3 1220534.B655_2035 8.058e-23 106.0 COG0500@1|root,arCOG01773@2157|Archaea,2Y131@28890|Euryarchaeota 28890|Euryarchaeota Q PFAM methyltransferase - - - - - - - - - - - - Methyltransf_23 DYD1_k127_6620150_0 1232410.KI421413_gene478 2.191e-98 334.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42UYG@68525|delta/epsilon subdivisions,2WR4P@28221|Deltaproteobacteria,43V2Y@69541|Desulfuromonadales 28221|Deltaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD1_k127_6620150_2 349521.HCH_05492 1.857e-24 103.0 COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,1XMNT@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0337 (CsbD) family - - - - - - - - - - - - CsbD DYD1_k127_6620150_3 1232410.KI421421_gene3350 3.961e-24 103.0 2DRFV@1|root,33BJD@2|Bacteria,1NM2T@1224|Proteobacteria,42WGX@68525|delta/epsilon subdivisions,2WR8G@28221|Deltaproteobacteria,43VJI@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6620150_4 1437882.AZRU01000031_gene63 2.105e-14 76.0 COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,1SGD7@1236|Gammaproteobacteria,1YH07@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S UPF0391 membrane protein ytjA - - - - - - - - - - - DUF1328 DYD1_k127_6620150_6 103733.JNYO01000044_gene6705 0.0001643 51.0 2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4E648@85010|Pseudonocardiales 201174|Actinobacteria S Putative Actinobacterial Holin-X, holin superfamily III - - - - - - - - - - - - Phage_holin_3_6 DYD1_k127_6620150_1 1167006.UWK_00212 1.543e-40 157.0 COG3047@1|root,COG3047@2|Bacteria 2|Bacteria - - - - - ko:K07275 - - - - ko00000 - - - OMP_b-brl,OmpA_like DYD1_k127_6621462_11 555779.Dthio_PD3174 2.831e-73 259.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria,2M9BD@213115|Desulfovibrionales 28221|Deltaproteobacteria O PFAM peptidase M48 Ste24p - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N DYD1_k127_6621462_1 378806.STAUR_6700 1.822e-299 935.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales 28221|Deltaproteobacteria O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD1_k127_6621462_16 1297742.A176_05580 7.235e-34 134.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2YVP9@29|Myxococcales 28221|Deltaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS DYD1_k127_6621462_18 1238182.C882_2850 1.005e-20 103.0 COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,2JRR5@204441|Rhodospirillales 204441|Rhodospirillales T signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_4 DYD1_k127_6621462_2 525904.Tter_0334 2.22e-180 583.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria 2|Bacteria C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N DYD1_k127_6621462_6 204669.Acid345_0599 1.186e-122 402.0 COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia 204432|Acidobacteriia C Pyruvate ferredoxin oxidoreductase beta subunit C terminal - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C DYD1_k127_6621462_12 1536769.P40081_05410 1.496e-56 205.0 COG1335@1|root,COG1335@2|Bacteria,1V2DX@1239|Firmicutes,4HFT9@91061|Bacilli,26V46@186822|Paenibacillaceae 91061|Bacilli Q Isochorismatase family - - 3.5.1.110 ko:K09020 ko00240,ko01100,map00240,map01100 - R09947,R09980 RC02737,RC02738 ko00000,ko00001,ko01000 - - - Isochorismatase DYD1_k127_6621462_8 1121440.AUMA01000003_gene2827 3.499e-105 350.0 COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MG8Q@213115|Desulfovibrionales 28221|Deltaproteobacteria H Probable molybdopterin binding domain - - - - - - - - - - - - MoCF_biosynth DYD1_k127_6621462_17 1197906.CAJQ02000034_gene2781 6.322e-27 113.0 COG0605@1|root,COG0607@1|root,COG0605@2|Bacteria,COG0607@2|Bacteria,1R4Z3@1224|Proteobacteria,2U38P@28211|Alphaproteobacteria,3JT9I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Iron/manganese superoxide dismutases, C-terminal domain - - - - - - - - - - - - Sod_Fe_C DYD1_k127_6621462_14 1366050.N234_35130 1.872e-49 181.0 COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2VN2K@28216|Betaproteobacteria,1K7D3@119060|Burkholderiaceae 28216|Betaproteobacteria P Iron/manganese superoxide dismutases, C-terminal domain - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Rhodanese,Sod_Fe_C DYD1_k127_6621462_13 1379698.RBG1_1C00001G0621 1.871e-52 188.0 COG4275@1|root,COG4275@2|Bacteria 2|Bacteria S Chromate resistance exported protein chrB - - - - - - - - - - - Chrome_Resist,HTH_18,Rhodanese DYD1_k127_6621462_5 381666.H16_B1483 9.511e-123 406.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,1K55C@119060|Burkholderiaceae 28216|Betaproteobacteria P TIGRFAM chromate transporter, chromate ion transporter (CHR) family chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD1_k127_6621462_15 189753.AXAS01000002_gene5413 1.418e-38 156.0 COG3391@1|root,COG3391@2|Bacteria,1RFWG@1224|Proteobacteria,2U7T8@28211|Alphaproteobacteria,3K2MV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S amine dehydrogenase activity - - - - - - - - - - - - - DYD1_k127_6621462_10 335543.Sfum_0094 1.275e-78 277.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WIJM@28221|Deltaproteobacteria,2MRAC@213462|Syntrophobacterales 28221|Deltaproteobacteria EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_6621462_7 1040989.AWZU01000073_gene3947 6.158e-116 382.0 COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria,3K2CR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Chromate resistance exported protein - - - - - - - - - - - - Chrome_Resist DYD1_k127_6621462_9 1366050.N234_35130 8.056e-91 302.0 COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2VN2K@28216|Betaproteobacteria,1K7D3@119060|Burkholderiaceae 28216|Betaproteobacteria P Iron/manganese superoxide dismutases, C-terminal domain - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Rhodanese,Sod_Fe_C DYD1_k127_6621462_4 452637.Oter_4441 1.625e-128 424.0 COG1538@1|root,COG1538@2|Bacteria,46VDP@74201|Verrucomicrobia,3K94B@414999|Opitutae 414999|Opitutae MU Outer membrane efflux protein - - - ko:K15725 - - - - ko00000,ko02000 1.B.17.2.2 - - OEP DYD1_k127_6621462_0 452637.Oter_4443 0.0 1252.0 COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,3K96P@414999|Opitutae 414999|Opitutae P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran DYD1_k127_6621462_3 1379698.RBG1_1C00001G0725 2.562e-145 468.0 COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria 2|Bacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Cation_efflux,ZT_dimer DYD1_k127_6621462_19 1340493.JNIF01000003_gene3147 4.479e-13 70.0 COG1695@1|root,COG1695@2|Bacteria,3Y5GY@57723|Acidobacteria 57723|Acidobacteria K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR DYD1_k127_6634726_21 104623.Ser39006_01242 6.759e-16 85.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,1T0VK@1236|Gammaproteobacteria,4048H@613|Serratia 1236|Gammaproteobacteria S Amidohydrolase - - 4.1.1.52 ko:K07045,ko:K22213 - - - - ko00000,ko01000 - - - Amidohydro_2 DYD1_k127_6634726_15 935840.JAEQ01000004_gene646 1.821e-43 171.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_6634726_12 1121423.JONT01000004_gene1654 5.931e-61 223.0 COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia,260GZ@186807|Peptococcaceae 186801|Clostridia E PFAM Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 DYD1_k127_6634726_1 1131269.AQVV01000024_gene2368 6.413e-174 560.0 COG4166@1|root,COG4166@2|Bacteria 2|Bacteria E transmembrane transport oppA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667 SBP_bac_5 DYD1_k127_6634726_18 627192.SLG_06520 2.421e-27 117.0 COG0511@1|root,COG0511@2|Bacteria,1N4VN@1224|Proteobacteria,2VGRT@28211|Alphaproteobacteria 28211|Alphaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA - - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl DYD1_k127_6634726_3 675635.Psed_3032 5.874e-171 549.0 COG0439@1|root,COG0439@2|Bacteria,2I2S0@201174|Actinobacteria,4DXG8@85010|Pseudonocardiales 201174|Actinobacteria I Biotin carboxylase C-terminal domain - - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD1_k127_6634726_5 1131269.AQVV01000006_gene529 3.977e-107 355.0 COG0601@1|root,COG0601@2|Bacteria 2|Bacteria P nitrogen compound transport oppB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 DYD1_k127_6634726_8 1131269.AQVV01000006_gene528 4.702e-78 270.0 COG1173@1|root,COG1173@2|Bacteria 2|Bacteria P ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02034,ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439,M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25 - iAF1260.b1245,iB21_1397.B21_01229,iEC55989_1330.EC55989_1342,iECBD_1354.ECBD_2377,iECB_1328.ECB_01219,iECDH10B_1368.ECDH10B_1307,iECDH1ME8569_1439.ECDH1ME8569_1185,iECD_1391.ECD_01219,iECIAI1_1343.ECIAI1_1264,iECO103_1326.ECO103_1345,iECO111_1330.ECO111_1572,iECO26_1355.ECO26_1756,iECSE_1348.ECSE_1293,iECSP_1301.ECSP_1637,iECUMN_1333.ECUMN_1542,iECW_1372.ECW_m1337,iECs_1301.ECs1745,iEKO11_1354.EKO11_2607,iETEC_1333.ETEC_1347,iEcDH1_1363.EcDH1_2403,iEcE24377_1341.EcE24377A_1393,iEcHS_1320.EcHS_A1354,iEcolC_1368.EcolC_2383,iG2583_1286.G2583_1517,iJO1366.b1245,iSSON_1240.SSON_1935,iUMNK88_1353.UMNK88_1565,iWFL_1372.ECW_m1337,iY75_1357.Y75_RS06515,iZ_1308.Z2021 BPD_transp_1,OppC_N DYD1_k127_6634726_20 443143.GM18_0461 4.982e-16 82.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,42ZR0@68525|delta/epsilon subdivisions,2WT3B@28221|Deltaproteobacteria,43UQ9@69541|Desulfuromonadales 28221|Deltaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_6634726_10 443143.GM18_0461 1.449e-70 245.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,42ZR0@68525|delta/epsilon subdivisions,2WT3B@28221|Deltaproteobacteria,43UQ9@69541|Desulfuromonadales 28221|Deltaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD1_k127_6634726_9 443143.GM18_0462 2.707e-75 272.0 COG4585@1|root,COG4585@2|Bacteria,1RKV1@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 DYD1_k127_6634726_14 330084.JNYZ01000035_gene9132 5.477e-45 168.0 COG5517@1|root,COG5517@2|Bacteria,2ITEX@201174|Actinobacteria 201174|Actinobacteria Q Ring hydroxylating beta subunit - - - - - - - - - - - - Ring_hydroxyl_B DYD1_k127_6634726_4 388401.RB2150_02274 1.425e-119 399.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,2TVEE@28211|Alphaproteobacteria,3ZIHC@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - 1.14.12.19 ko:K00479,ko:K05708,ko:K14748 ko00360,ko00642,ko01100,ko01120,ko01220,map00360,map00642,map01100,map01120,map01220 M00545 R05440,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A DYD1_k127_6634726_7 1124780.ANNU01000072_gene1056 1.425e-85 301.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_6634726_11 883126.HMPREF9710_01329 1.398e-65 243.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,472VG@75682|Oxalobacteraceae 28216|Betaproteobacteria S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD1_k127_6634726_17 312153.Pnuc_1339 2.03e-31 128.0 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,1K8P2@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM GCN5-related N-acetyltransferase yjcF - - - - - - - - - - - 4HBT,Acetyltransf_10 DYD1_k127_6634726_16 99598.Cal7507_4477 1.547e-36 144.0 COG0625@1|root,COG0625@2|Bacteria,1G4XE@1117|Cyanobacteria,1HM97@1161|Nostocales 1117|Cyanobacteria O PFAM Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 DYD1_k127_6634726_19 1224164.B843_00440 2.61e-20 96.0 COG5496@1|root,COG5496@2|Bacteria,2ISPN@201174|Actinobacteria,22PCD@1653|Corynebacteriaceae 201174|Actinobacteria S Thioesterase superfamily - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042802,GO:0042803,GO:0046983 3.1.2.29 ko:K18700 - - - - ko00000,ko01000 - - - 4HBT DYD1_k127_6634726_13 1231391.AMZF01000037_gene592 1.35e-56 209.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2VIUC@28216|Betaproteobacteria,3T4R5@506|Alcaligenaceae 28216|Betaproteobacteria S Nitronate monooxygenase - - 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO DYD1_k127_6634726_6 1504672.669786953 1.708e-102 349.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae 28216|Betaproteobacteria I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD1_k127_6634726_0 1499967.BAYZ01000036_gene2418 0.0 1291.0 COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_6634726_2 1499967.BAYZ01000036_gene2419 7.106e-173 546.0 COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria 2|Bacteria G beta-1,4-mannooligosaccharide phosphorylase - - - - - - - - - - - - Glyco_hydro_130 DYD1_k127_6675408_4 1157637.KB892121_gene295 1.661e-22 102.0 COG0662@1|root,COG0662@2|Bacteria,2IN75@201174|Actinobacteria 201174|Actinobacteria G PFAM Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 DYD1_k127_6675408_1 313624.NSP_50570 1.029e-60 222.0 COG1028@1|root,COG1028@2|Bacteria,1G4S8@1117|Cyanobacteria,1HNVP@1161|Nostocales 1117|Cyanobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059,ko:K19550 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572,M00787 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11067,R11671 RC00029,RC00117,RC03342 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_6675408_2 266264.Rmet_5214 5.417e-35 138.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria,1K74B@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_6675408_0 1123023.JIAI01000012_gene9107 4.714e-95 323.0 COG0715@1|root,COG0715@2|Bacteria,2IEVS@201174|Actinobacteria,4E6SW@85010|Pseudonocardiales 201174|Actinobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - SBP_bac_3 DYD1_k127_6675408_3 1128398.Curi_c07140 9.976e-28 114.0 COG3118@1|root,COG3118@2|Bacteria,1UI3G@1239|Firmicutes,25FW5@186801|Clostridia 186801|Clostridia O belongs to the thioredoxin family - - - - - - - - - - - - Arylsulfotrans,Thioredoxin DYD1_k127_670649_1 880072.Desac_0206 7.367e-09 66.0 2BHJK@1|root,32BN1@2|Bacteria,1RJW9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_670649_0 935840.JAEQ01000002_gene3498 5.215e-49 178.0 COG0346@1|root,COG0346@2|Bacteria,1PKTJ@1224|Proteobacteria,2UZFD@28211|Alphaproteobacteria,43PU2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD1_k127_670649_2 1144319.PMI16_02018 0.0002 53.0 COG0715@1|root,COG0715@2|Bacteria,1R9FK@1224|Proteobacteria 1224|Proteobacteria P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6715490_3 679200.HMPREF9333_01214 2.163e-06 59.0 COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia 186801|Clostridia P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth DYD1_k127_6715490_0 350058.Mvan_1001 2.556e-71 256.0 COG4638@1|root,COG4638@2|Bacteria,2GKMV@201174|Actinobacteria,236I0@1762|Mycobacteriaceae 201174|Actinobacteria P Rieske [2Fe-2S] domain vanA - - ko:K19982 ko00404,ko01130,map00404,map01130 M00790 R11107 RC01333 ko00000,ko00001,ko00002,ko01000 - - - Rieske DYD1_k127_6715490_1 457421.CBFG_04453 2.605e-24 115.0 COG1878@1|root,COG1878@2|Bacteria 2|Bacteria S arylformamidase activity - - - - - - - - - - - - Cyclase DYD1_k127_6715490_2 457421.CBFG_04453 1.638e-16 89.0 COG1878@1|root,COG1878@2|Bacteria 2|Bacteria S arylformamidase activity - - - - - - - - - - - - Cyclase DYD1_k127_6720133_0 330214.NIDE2073 7.621e-304 943.0 COG1389@1|root,COG1389@2|Bacteria 2|Bacteria L DNA topoisomerase II activity top6B - 5.99.1.3 ko:K03167 - - - - ko00000,ko01000,ko03032 - - - HATPase_c,HATPase_c_3,Topo-VIb_trans DYD1_k127_6720133_3 1120949.KB903314_gene304 3.692e-96 327.0 2C1EV@1|root,33RW1@2|Bacteria,2ICZG@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD1_k127_6720133_4 1173021.ALWA01000026_gene2720 1.929e-78 271.0 28JPA@1|root,2Z9FC@2|Bacteria,1G2DB@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD1_k127_6720133_2 1231391.AMZF01000110_gene916 2.543e-237 747.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_6720133_1 1231391.AMZF01000110_gene916 3.753e-244 766.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_6720777_5 1041147.AUFB01000004_gene4875 5.101e-15 86.0 COG0715@1|root,COG0715@2|Bacteria,1R3SJ@1224|Proteobacteria,2VEU8@28211|Alphaproteobacteria,4BD64@82115|Rhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_6720777_1 1469245.JFBG01000009_gene565 1.792e-66 236.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RQNH@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Rhodanese-like domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD1_k127_6720777_0 671143.DAMO_3054 7.683e-111 377.0 COG5621@1|root,COG5621@2|Bacteria,2NPFN@2323|unclassified Bacteria 2|Bacteria S Lipocalin-like domain attH - - - - - - - - - - - CrtC,Lipocalin_9 DYD1_k127_6720777_2 395961.Cyan7425_1646 2.056e-35 142.0 COG2402@1|root,COG2402@2|Bacteria,1G56E@1117|Cyanobacteria,3KJUH@43988|Cyanothece 1117|Cyanobacteria S nucleic acid-binding protein, contains PIN domain - - - ko:K07065 - - - - ko00000 - - - PIN DYD1_k127_6720777_4 1173264.KI913949_gene4203 5.219e-19 91.0 COG4691@1|root,COG4691@2|Bacteria,1G9I8@1117|Cyanobacteria,1HGF7@1150|Oscillatoriales 1117|Cyanobacteria S Plasmid stability protein - - - - - - - - - - - - - DYD1_k127_6720777_7 1173027.Mic7113_3432 1.336e-09 62.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales 1117|Cyanobacteria O Tetratricopeptide repeat - - - - - - - - - - - - ANAPC5,CHAT,TPR_12,TPR_7,TPR_8 DYD1_k127_6720777_3 292564.Cyagr_1980 1.555e-27 116.0 COG1487@1|root,COG1487@2|Bacteria 2|Bacteria S nuclease activity - - - - - - - - - - - - PIN DYD1_k127_6720777_6 180281.CPCC7001_2663 9.902e-12 69.0 COG2002@1|root,COG2002@2|Bacteria,1GGYY@1117|Cyanobacteria,22TVR@167375|Cyanobium 1117|Cyanobacteria K TIGRFAM looped-hinge helix DNA binding domain, AbrB family - - - - - - - - - - - - - DYD1_k127_6723496_1 1123228.AUIH01000010_gene4016 2.542e-37 145.0 COG0824@1|root,COG0824@2|Bacteria,1PF95@1224|Proteobacteria,1SBBS@1236|Gammaproteobacteria,1XM08@135619|Oceanospirillales 135619|Oceanospirillales S Thioesterase superfamily - - 3.1.2.23 ko:K01075 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - - 4HBT DYD1_k127_6723496_3 571166.KI421509_gene2039 5.846e-16 79.0 COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria,2U421@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD1_k127_6723496_0 1095769.CAHF01000011_gene2117 3.703e-68 241.0 COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2VIUS@28216|Betaproteobacteria 28216|Betaproteobacteria S N-terminal half of MaoC dehydratase - - 4.2.1.153,4.2.1.56 ko:K09709,ko:K18291 ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200 M00376 R02491,R09282 RC00730,RC02479 ko00000,ko00001,ko00002,ko01000 - - - MaoC_dehydrat_N DYD1_k127_6723496_2 485913.Krac_1828 1.69e-26 120.0 COG0596@1|root,COG0596@2|Bacteria,2G8Y9@200795|Chloroflexi 2|Bacteria S COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 DYD1_k127_6723496_4 485913.Krac_10854 9.393e-07 58.0 COG0819@1|root,COG0819@2|Bacteria 2|Bacteria K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 DYD1_k127_673121_5 484022.Fphi_0291 1.042e-26 114.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,460NV@72273|Thiotrichales 72273|Thiotrichales M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD1_k127_673121_6 153721.MYP_1801 2.09e-21 107.0 28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,47NK3@768503|Cytophagia 976|Bacteroidetes S Putative beta-barrel porin-2, OmpL-like. bbp2 - - - - - - - - - - - - BBP2 DYD1_k127_673121_4 671143.DAMO_2790 5.419e-48 181.0 COG0518@1|root,COG0518@2|Bacteria,2NPS4@2323|unclassified Bacteria 2|Bacteria F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase DYD1_k127_673121_0 671143.DAMO_1697 8.334e-215 678.0 COG0004@1|root,COG0004@2|Bacteria,2NP8F@2323|unclassified Bacteria 2|Bacteria P Ammonium Transporter Family nrgA - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp DYD1_k127_673121_2 671143.DAMO_1053 2.773e-49 179.0 COG0347@1|root,COG0347@2|Bacteria,2NR63@2323|unclassified Bacteria 2|Bacteria K Nitrogen regulatory protein P-II - - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II DYD1_k127_673121_1 1449126.JQKL01000045_gene1963 2.159e-83 286.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,269N4@186813|unclassified Clostridiales 186801|Clostridia S Carbon-nitrogen hydrolase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase DYD1_k127_673121_3 123214.PERMA_1283 6.677e-49 184.0 COG0589@1|root,COG0589@2|Bacteria,2G4YU@200783|Aquificae 200783|Aquificae T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD1_k127_6731734_2 710686.Mycsm_01832 4.804e-49 188.0 COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria 201174|Actinobacteria S NMT1-like family - - - - - - - - - - - - NMT1_3 DYD1_k127_6731734_1 105425.BBPL01000045_gene3219 1.01e-84 299.0 COG1032@1|root,COG1032@2|Bacteria,2GZU1@201174|Actinobacteria,2NI0T@228398|Streptacidiphilus 201174|Actinobacteria C radical SAM domain protein - - - - - - - - - - - - - DYD1_k127_6731734_3 670487.Ocepr_0065 9.824e-39 152.0 COG4122@1|root,COG4122@2|Bacteria,1WKHV@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S O-methyltransferase - - - - - - - - - - - - Methyltransf_3 DYD1_k127_6731734_0 1120972.AUMH01000006_gene1898 1.161e-90 312.0 COG4638@1|root,COG4638@2|Bacteria 2|Bacteria P Rieske (2fe-2S) ligX - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske DYD1_k127_674810_3 1382306.JNIM01000001_gene3716 1.662e-70 248.0 COG1028@1|root,COG1028@2|Bacteria,2G8CF@200795|Chloroflexi 200795|Chloroflexi IQ PFAM short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short,adh_short_C2 DYD1_k127_674810_4 399739.Pmen_1471 7.836e-56 209.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1YEPT@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Trypsin mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_674810_0 401526.TcarDRAFT_2671 2.382e-241 770.0 COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,4H23V@909932|Negativicutes 909932|Negativicutes O Belongs to the peptidase S16 family - - - - - - - - - - - - AAA_32,Lon_C DYD1_k127_674810_5 933262.AXAM01000050_gene3492 4.713e-51 199.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2MHRK@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM peptidase - - - - - - - - - - - iAF987.Gmet_1238 Peptidase_M48,TPR_14,TPR_16,TPR_19 DYD1_k127_674810_6 1122915.AUGY01000020_gene6470 1.163e-38 154.0 COG0235@1|root,COG0235@2|Bacteria 2|Bacteria G Class ii aldolase - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II,UPF0066 DYD1_k127_674810_8 1174528.JH992898_gene4329 6.295e-07 55.0 COG2161@1|root,COG2161@2|Bacteria,1G9CI@1117|Cyanobacteria 1117|Cyanobacteria D Antitoxin component of a toxin-antitoxin (TA) module - - - - - - - - - - - - PhdYeFM_antitox DYD1_k127_674810_2 1158294.JOMI01000003_gene2397 8.49e-95 323.0 COG0451@1|root,COG0451@2|Bacteria,4P1QM@976|Bacteroidetes,2FX1I@200643|Bacteroidia 976|Bacteroidetes GM NmrA-like family - - - - - - - - - - - - Epimerase DYD1_k127_674810_1 479434.Sthe_0262 1.308e-99 342.0 COG0402@1|root,COG0402@2|Bacteria,2G8TD@200795|Chloroflexi,27ZAA@189775|Thermomicrobia 189775|Thermomicrobia F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD1_k127_674810_7 318996.AXAZ01000008_gene4296 8.113e-16 77.0 COG2984@1|root,COG2984@2|Bacteria,1NPJJ@1224|Proteobacteria,2UUMS@28211|Alphaproteobacteria,3K4MG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - - - - - - - - - - ABC_sub_bind DYD1_k127_6754423_3 65497.JODV01000012_gene2387 1.255e-09 62.0 COG2186@1|root,COG2186@2|Bacteria,2GP3H@201174|Actinobacteria,4EC2J@85010|Pseudonocardiales 201174|Actinobacteria K FCD - - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR DYD1_k127_6754423_2 273057.SSO2128 4.441e-103 348.0 COG1144@1|root,arCOG01604@2157|Archaea,2XRKM@28889|Crenarchaeota 28889|Crenarchaeota C Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like) - - 1.2.7.1 ko:K00171 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4_21 DYD1_k127_6754423_0 266117.Rxyl_0920 3.488e-156 502.0 COG0674@1|root,COG0674@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor porA GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 ko:K00169,ko:K19070 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N DYD1_k127_6754423_1 399549.Msed_1199 6.63e-111 365.0 COG1013@1|root,arCOG01601@2157|Archaea,2XPVE@28889|Crenarchaeota 28889|Crenarchaeota C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.1 ko:K00170 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C DYD1_k127_6757262_3 370438.PTH_0373 1.93e-28 116.0 COG2002@1|root,COG2002@2|Bacteria,1W0E3@1239|Firmicutes,25369@186801|Clostridia 186801|Clostridia K SpoVT / AbrB like domain - - - - - - - - - - - - MazE_antitoxin DYD1_k127_6757262_1 410358.Mlab_0450 8.37e-41 154.0 COG0537@1|root,arCOG00419@2157|Archaea,2Y0J5@28890|Euryarchaeota,2NA21@224756|Methanomicrobia 224756|Methanomicrobia F PFAM histidine triad (HIT) protein - - - - - - - - - - - - HIT DYD1_k127_6757262_2 1231391.AMZF01000069_gene2126 1.044e-30 134.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_6757262_0 189753.AXAS01000041_gene2534 2.343e-46 180.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6766676_2 443152.MDG893_15285 2.529e-18 89.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctA DYD1_k127_6766676_3 443152.MDG893_15295 2.271e-06 54.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_6766676_0 76114.p2A120 7.452e-141 462.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD1_k127_6766676_1 1382304.JNIL01000001_gene3039 2.694e-41 165.0 COG0329@1|root,COG0329@2|Bacteria,1TPVS@1239|Firmicutes,4HATJ@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD1_k127_6798800_0 324602.Caur_2029 1.006e-131 430.0 COG3177@1|root,COG3177@2|Bacteria,2G82E@200795|Chloroflexi,3773U@32061|Chloroflexia 32061|Chloroflexia S PFAM filamentation induced by cAMP protein Fic - - - - - - - - - - - - Fic,Fic_N DYD1_k127_6798800_2 1123368.AUIS01000024_gene953 1.256e-54 198.0 COG2890@1|root,COG2890@2|Bacteria,1MY5I@1224|Proteobacteria,1T26C@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase (PrmA) - - - - - - - - - - - - Methyltransf_31,PrmA DYD1_k127_6798800_3 1128398.Curi_c28060 1.524e-20 99.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24A9U@186801|Clostridia,269GH@186813|unclassified Clostridiales 186801|Clostridia Q Isochorismatase family - - - - - - - - - - - - Isochorismatase DYD1_k127_6798800_1 189753.AXAS01000041_gene2534 8.557e-93 317.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_6798800_5 1519464.HY22_13865 1.254e-08 58.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD1_k127_6798800_4 65497.JODV01000001_gene3457 4.992e-11 67.0 COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4E2X5@85010|Pseudonocardiales 201174|Actinobacteria O PFAM AhpC TSA family ahpE GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - AhpC-TSA DYD1_k127_6802037_8 1038860.AXAP01000087_gene3814 1.184e-13 78.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV3I@28211|Alphaproteobacteria,3JS2U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Rieske [2Fe-2S] domain - - 1.14.13.229,1.14.19.48 ko:K21323 - - - - ko00000,ko01000 - - - Rieske,Ring_hydroxyl_A DYD1_k127_6802037_4 1382356.JQMP01000003_gene1734 1.715e-54 203.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - 4.1.1.55 ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000 - - - NMT1 DYD1_k127_6802037_5 312153.Pnuc_0551 5.507e-40 153.0 COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2VUSK@28216|Betaproteobacteria,1K8WQ@119060|Burkholderiaceae 28216|Betaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading DYD1_k127_6802037_1 1356854.N007_08200 3.319e-93 316.0 COG3384@1|root,COG3384@2|Bacteria 2|Bacteria S 3-carboxyethylcatechol 2,3-dioxygenase activity - - 1.13.11.16 ko:K05713 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R04376,R06788 RC01140,RC01364 br01602,ko00000,ko00001,ko00002,ko01000 - - - LigB DYD1_k127_6802037_6 195253.Syn6312_2648 1.011e-19 94.0 COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria,1H0QZ@1129|Synechococcus 1117|Cyanobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD1_k127_6802037_2 443152.MDG893_15065 1.797e-92 314.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,1RQG7@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components phtD - - - - - - - - - - - NMT1 DYD1_k127_6802037_7 1125863.JAFN01000001_gene867 2.356e-17 83.0 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,42XRW@68525|delta/epsilon subdivisions,2WT0E@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG - - ko:K09862 - - - - ko00000 - - - YacG DYD1_k127_6802037_3 269799.Gmet_2567 2.281e-85 289.0 COG1043@1|root,COG1043@2|Bacteria,1R8TC@1224|Proteobacteria,42MH4@68525|delta/epsilon subdivisions,2WJYN@28221|Deltaproteobacteria,43SC1@69541|Desulfuromonadales 28221|Deltaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA-2 - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF987.Gmet_2567 Acetyltransf_11,Hexapep DYD1_k127_6802037_9 1283300.ATXB01000001_gene259 6.85e-13 74.0 2DGQ2@1|root,2ZWWE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD1_k127_6802037_0 269799.Gmet_0071 2.159e-210 689.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales 28221|Deltaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE DYD1_k127_6806696_0 189753.AXAS01000001_gene3946 1.652e-74 264.0 COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2U0CV@28211|Alphaproteobacteria,3JVF6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - 1.14.13.235 ko:K22027 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_2,Acyl-CoA_dh_N DYD1_k127_6806696_1 1463936.JOJI01000029_gene3267 2.115e-33 145.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria 201174|Actinobacteria S Pfam Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_6809226_1 1120983.KB894572_gene3272 8.404e-86 296.0 COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2TVJ9@28211|Alphaproteobacteria,1JQ4A@119043|Rhodobiaceae 28211|Alphaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_6809226_3 240302.BN982_03238 3.893e-16 84.0 COG3945@1|root,COG3945@2|Bacteria,1VD5M@1239|Firmicutes,4HM3K@91061|Bacilli,3NFPR@45667|Halobacillus 91061|Bacilli S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin DYD1_k127_6809226_2 331869.BAL199_17958 6.732e-37 144.0 2DS7S@1|root,33EWX@2|Bacteria,1NDGE@1224|Proteobacteria,2UH4Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_6809226_4 591158.SSMG_07229 2.284e-14 77.0 COG1917@1|root,COG1917@2|Bacteria,2H4TQ@201174|Actinobacteria 201174|Actinobacteria S Cupin - - - - - - - - - - - - Cupin_2 DYD1_k127_6809226_0 1459636.NTE_00100 6.842e-93 314.0 COG0388@1|root,arCOG00062@2157|Archaea,41SF8@651137|Thaumarchaeota 651137|Thaumarchaeota S Carbon-nitrogen hydrolase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase DYD1_k127_6809226_5 1038869.AXAN01000015_gene3058 3.89e-07 53.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2VT4N@28216|Betaproteobacteria,1KGVW@119060|Burkholderiaceae 28216|Betaproteobacteria E Ectoine utilization protein EutC - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_6819098_4 1246995.AFR_15015 1.502e-23 106.0 COG3055@1|root,COG3055@2|Bacteria,2ICH5@201174|Actinobacteria,4DFPE@85008|Micromonosporales 201174|Actinobacteria S Galactose oxidase, central domain - - - - - - - - - - - - Kelch_1,Kelch_6 DYD1_k127_6819098_2 631454.N177_1465 3.555e-47 176.0 29CWT@1|root,2ZZUX@2|Bacteria,1REF2@1224|Proteobacteria,2U7K7@28211|Alphaproteobacteria,1JQ26@119043|Rhodobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2585) - - - - - - - - - - - - DUF2585 DYD1_k127_6819098_5 1173264.KI913949_gene1725 0.0002972 50.0 COG0265@1|root,COG1413@1|root,COG5635@1|root,COG0265@2|Bacteria,COG1413@2|Bacteria,COG5635@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales 1117|Cyanobacteria C PBS lyase HEAT-like repeat - - - - - - - - - - - - HEAT_2,HEAT_PBS,Metallophos,NACHT,Trypsin_2 DYD1_k127_6819098_1 1266925.JHVX01000002_gene943 1.19e-60 211.0 COG4319@1|root,COG4319@2|Bacteria,1NFP9@1224|Proteobacteria,2WGCH@28216|Betaproteobacteria 28216|Betaproteobacteria S SnoaL-like domain - - - - - - - - - - - - DUF4440 DYD1_k127_6819098_0 1499967.BAYZ01000024_gene278 6.875e-75 259.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion - - - - - - - - - - - - Band_7 DYD1_k127_6846625_5 204773.HEAR3280 3.489e-16 82.0 COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,2VS4H@28216|Betaproteobacteria,474WC@75682|Oxalobacteraceae 28216|Betaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin DYD1_k127_6846625_1 1254432.SCE1572_41890 1.369e-270 848.0 COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2YX9T@29|Myxococcales 28221|Deltaproteobacteria G High confidence in function and specificity - - - - - - - - - - - - GDE_C,GDE_N DYD1_k127_6846625_0 1232410.KI421416_gene2671 1.188e-270 847.0 COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,42MKI@68525|delta/epsilon subdivisions,2WM5H@28221|Deltaproteobacteria,43TX2@69541|Desulfuromonadales 28221|Deltaproteobacteria G Domain of unknown function (DUF3459) treZ-2 - 3.2.1.141 ko:K01236 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11256 RC00049 ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3459 DYD1_k127_6846625_2 234267.Acid_5076 9.6e-138 448.0 COG3285@1|root,COG3285@2|Bacteria,3Y74I@57723|Acidobacteria 57723|Acidobacteria L dna ligase - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - - DYD1_k127_6846625_3 204669.Acid345_3971 2.829e-45 171.0 2ADQJ@1|root,313FX@2|Bacteria,3Y7U5@57723|Acidobacteria,2JN16@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - DYD1_k127_6846625_4 204669.Acid345_3970 2.397e-30 124.0 2DQJB@1|root,3377V@2|Bacteria,3Y8JD@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - DYD1_k127_6846625_6 314278.NB231_04290 8.05e-16 80.0 COG1537@1|root,COG1537@2|Bacteria,1R36N@1224|Proteobacteria,1T642@1236|Gammaproteobacteria 1236|Gammaproteobacteria S nuclear-transcribed mRNA catabolic process, no-go decay - - - - - - - - - - - - - DYD1_k127_6861751_1 1379698.RBG1_1C00001G1238 4.021e-48 192.0 COG5000@1|root,COG5000@2|Bacteria,2NQEP@2323|unclassified Bacteria 2|Bacteria T COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1 DYD1_k127_6861751_0 589865.DaAHT2_1070 1.468e-94 317.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIQF@213118|Desulfobacterales 28221|Deltaproteobacteria T response regulator receiver - - - ko:K02481 - - - - ko00000,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_6864875_21 1123023.JIAI01000007_gene1665 6.891e-22 99.0 COG0715@1|root,COG0715@2|Bacteria,2HZMX@201174|Actinobacteria,4E025@85010|Pseudonocardiales 201174|Actinobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - DYD1_k127_6864875_17 1210884.HG799464_gene10511 3.118e-41 165.0 COG2423@1|root,COG2423@2|Bacteria,2IXT1@203682|Planctomycetes 203682|Planctomycetes E ornithine cyclodeaminase mu-crystallin - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD1_k127_6864875_11 1297617.JPJD01000050_gene1926 3.051e-83 295.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,2697G@186813|unclassified Clostridiales 186801|Clostridia H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ubiD - - ko:K16874 ko00365,ko01120,map00365,map01120 - R10213 RC03086 ko00000,ko00001 - - - UbiD DYD1_k127_6864875_3 671143.DAMO_3035 6.4e-135 445.0 COG1232@1|root,COG1232@2|Bacteria 2|Bacteria H protoporphyrinogen oxidase activity hemG - 1.14.19.9,1.3.3.15,1.3.3.4 ko:K00231,ko:K14266 ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130 M00121,M00789,M00790 R03222,R04178,R09570 RC00885,RC00949 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase DYD1_k127_6864875_10 671143.DAMO_3034 8.396e-88 299.0 COG0276@1|root,COG0276@2|Bacteria,2NQ0V@2323|unclassified Bacteria 2|Bacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase DYD1_k127_6864875_2 671143.DAMO_3033 5.112e-141 455.0 COG0407@1|root,COG1587@1|root,COG0407@2|Bacteria,COG1587@2|Bacteria,2NP39@2323|unclassified Bacteria 2|Bacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 ko:K01599,ko:K01719,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194,R03197,R04972 RC00003,RC00871,RC00872,RC01861 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0016 HEM4,Trans_reg_C,URO-D DYD1_k127_6864875_12 234267.Acid_0850 4.219e-79 280.0 COG0389@1|root,COG0389@2|Bacteria,3Y3NY@57723|Acidobacteria 57723|Acidobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH DYD1_k127_6864875_9 635013.TherJR_0520 1.22e-89 314.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,2610Z@186807|Peptococcaceae 186801|Clostridia U TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD1_k127_6864875_0 671143.DAMO_1073 0.0 1169.0 COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria 2|Bacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K03694,ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD1_k127_6864875_19 368408.Tpen_0524 1.118e-36 150.0 COG0467@1|root,arCOG01171@2157|Archaea,2XRYY@28889|Crenarchaeota 28889|Crenarchaeota T Circadian clock protein KaiC - - - ko:K08482 - - - - ko00000 - - - ATPase DYD1_k127_6864875_20 368408.Tpen_0524 1.293e-36 148.0 COG0467@1|root,arCOG01171@2157|Archaea,2XRYY@28889|Crenarchaeota 28889|Crenarchaeota T Circadian clock protein KaiC - - - ko:K08482 - - - - ko00000 - - - ATPase DYD1_k127_6864875_6 247490.KSU1_C0302 3.142e-112 373.0 COG0079@1|root,COG0079@2|Bacteria,2IWYA@203682|Planctomycetes 203682|Planctomycetes E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD1_k127_6864875_18 446470.Snas_1685 5.839e-37 145.0 COG0346@1|root,COG0346@2|Bacteria,2II0X@201174|Actinobacteria 201174|Actinobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD1_k127_6864875_5 671143.DAMO_2633 9.657e-129 424.0 COG1253@1|root,COG1253@2|Bacteria,2NP04@2323|unclassified Bacteria 2|Bacteria S Transporter associated domain ytfL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03699,ko:K06189 - - - - ko00000,ko02000,ko02042 9.A.40.1.2 - - CBS,CorC_HlyC,DUF21,TerC DYD1_k127_6864875_1 671143.DAMO_0393 3.664e-218 699.0 COG0507@1|root,COG0507@2|Bacteria,2NNQY@2323|unclassified Bacteria 2|Bacteria L Helix-hairpin-helix containing domain recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 DYD1_k127_6864875_16 70601.3257399 1.462e-41 163.0 COG3473@1|root,arCOG02004@2157|Archaea,2XUJ3@28890|Euryarchaeota,24328@183968|Thermococci 28890|Euryarchaeota Q Asp/Glu/Hydantoin racemase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD1_k127_6864875_7 1192034.CAP_6251 7.599e-112 373.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 1224|Proteobacteria S Amidohydrolase MA20_19310 - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_6864875_26 118173.KB235914_gene3004 4.258e-09 59.0 COG0834@1|root,COG0834@2|Bacteria,1G36J@1117|Cyanobacteria,1HBPC@1150|Oscillatoriales 1117|Cyanobacteria ET amino acid ABC transporter substrate-binding protein, PAAT family - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - Ion_trans_2,Lig_chan,SBP_bac_3 DYD1_k127_6864875_27 1379698.RBG1_1C00001G1254 4.523e-05 53.0 COG4796@1|root,COG4796@2|Bacteria,2NPEQ@2323|unclassified Bacteria 2|Bacteria U Secretin and TonB N terminus short domain - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N DYD1_k127_6864875_25 1122915.AUGY01000020_gene6479 4.622e-19 99.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_6864875_14 1265310.CCBD010000061_gene1162 6.001e-55 209.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_6864875_4 309801.trd_A0900 2.302e-132 434.0 COG1060@1|root,COG1060@2|Bacteria,2G7YI@200795|Chloroflexi,27YSR@189775|Thermomicrobia 189775|Thermomicrobia H Elongator protein 3, MiaB family, Radical SAM - - 2.5.1.77 ko:K11779 ko00680,ko01120,map00680,map01120 M00378 R09396 RC01381,RC03002,RC03007 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM DYD1_k127_6864875_8 1382306.JNIM01000001_gene1897 2.741e-91 310.0 COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi 200795|Chloroflexi S TIGRFAM LPPG domain protein containing protein cofD - 2.7.8.28 ko:K11212 ko00680,ko01120,map00680,map01120 M00378 R09398 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - UPF0052 DYD1_k127_6864875_22 247634.GPB2148_1664 7.32e-21 101.0 COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,1RSCG@1236|Gammaproteobacteria,1J4W0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Elongator protein 3, MiaB family, Radical SAM - - 2.5.1.77 ko:K11779 ko00680,ko01120,map00680,map01120 M00378 R09396 RC01381,RC03002,RC03007 ko00000,ko00001,ko00002,ko01000 - - - CofC,Radical_SAM DYD1_k127_6864875_13 309801.trd_A0548 2.559e-67 237.0 COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi,27XFS@189775|Thermomicrobia 189775|Thermomicrobia S F420-0:Gamma-glutamyl ligase - - 6.3.2.31,6.3.2.34 ko:K12234 ko00680,ko01120,map00680,map01120 M00378 R09399,R09400 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000 - - - F420_ligase DYD1_k127_6864875_15 1042375.AFPL01000013_gene2461 6.61e-43 164.0 COG2085@1|root,COG2085@2|Bacteria,1MXS0@1224|Proteobacteria,1S2WU@1236|Gammaproteobacteria,46836@72275|Alteromonadaceae 1236|Gammaproteobacteria S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD1_k127_6864875_23 292415.Tbd_1946 1.047e-19 98.0 2EV5S@1|root,33NKJ@2|Bacteria,1NI0N@1224|Proteobacteria,2VYM4@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3568) - - - - - - - - - - - - DUF3568 DYD1_k127_6864875_24 748247.AZKH_2168 1.202e-19 97.0 2E4BS@1|root,32Z7C@2|Bacteria,1NBM8@1224|Proteobacteria,2VXEQ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_688611_6 589924.Ferp_0082 2.726e-97 323.0 COG0410@1|root,arCOG00924@2157|Archaea,2XTUG@28890|Euryarchaeota,246XP@183980|Archaeoglobi 28890|Euryarchaeota E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD1_k127_688611_5 589924.Ferp_0081 8.366e-99 329.0 COG0411@1|root,arCOG00926@2157|Archaea,2Y7A8@28890|Euryarchaeota,2473S@183980|Archaeoglobi 183980|Archaeoglobi E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD1_k127_688611_2 1265505.ATUG01000001_gene3612 1.534e-110 366.0 COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria,2MJX3@213118|Desulfobacterales 28221|Deltaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_688611_8 706587.Desti_0905 1.731e-89 303.0 COG0559@1|root,COG0559@2|Bacteria,1PAWF@1224|Proteobacteria,42MQG@68525|delta/epsilon subdivisions,2WKQ5@28221|Deltaproteobacteria 2|Bacteria U PFAM Branched-chain amino acid transport system permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD1_k127_688611_0 706587.Desti_0906 1.148e-154 499.0 COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,42NFF@68525|delta/epsilon subdivisions,2WKDK@28221|Deltaproteobacteria 1224|Proteobacteria E Amino acid amide ABC transporter substrate-binding protein, HAAT family - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD1_k127_688611_15 443152.MDG893_15075 1.163e-31 137.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_688611_16 391937.NA2_01719 1.663e-26 113.0 COG0251@1|root,COG0251@2|Bacteria,1REKH@1224|Proteobacteria,2VFGK@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD1_k127_688611_18 1238182.C882_0928 1.248e-05 53.0 2ADQZ@1|root,313GA@2|Bacteria,1Q1IG@1224|Proteobacteria,2V99D@28211|Alphaproteobacteria,2JUU5@204441|Rhodospirillales 204441|Rhodospirillales S Domain of unknown function (DUF4168) - - - - - - - - - - - - DUF4168 DYD1_k127_688611_11 196490.AUEZ01000075_gene7649 2.71e-79 280.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups dgtA - - - - - - - - - - - Glyco_tran_WbsX,Glycos_transf_1,Glycos_transf_2 DYD1_k127_688611_12 1123514.KB905899_gene437 1.416e-70 248.0 COG1215@1|root,COG1215@2|Bacteria,1QVXA@1224|Proteobacteria,1T2MS@1236|Gammaproteobacteria 1236|Gammaproteobacteria M GtrA-like protein - - - - - - - - - - - - Glycos_transf_2,GtrA DYD1_k127_688611_14 859657.RPSI07_1495 1.937e-32 132.0 2EERN@1|root,338JC@2|Bacteria,1NCUD@1224|Proteobacteria,2VWBR@28216|Betaproteobacteria,1K9RV@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_688611_10 1205680.CAKO01000007_gene4355 7.726e-82 282.0 COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM amidohydrolase 2 - - - - - - - - - - - - Amidohydro_2 DYD1_k127_688611_1 330214.NIDE3398 2.133e-127 421.0 COG1653@1|root,COG1653@2|Bacteria 2|Bacteria G carbohydrate transport thuE - - ko:K02027,ko:K10236 ko02010,map02010 M00204,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.17 - - SBP_bac_1,SBP_bac_8 DYD1_k127_688611_7 706587.Desti_1277 3.13e-97 329.0 COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,42SSV@68525|delta/epsilon subdivisions,2WP8Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component thuF - - ko:K02025,ko:K10237 ko02010,map02010 M00204,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.17 - - BPD_transp_1 DYD1_k127_688611_9 706587.Desti_1276 3.061e-89 304.0 COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,42S2T@68525|delta/epsilon subdivisions,2WNIH@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Binding-protein-dependent transport system inner membrane component thuG - - ko:K02026,ko:K10238 ko02010,map02010 M00204,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.17 - - BPD_transp_1 DYD1_k127_688611_3 910964.GEAM_3871 1.384e-104 351.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily ugpC GO:0000166,GO:0001406,GO:0001407,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055052,GO:0055085,GO:0071702,GO:0071944,GO:0097159,GO:0097367,GO:0098533,GO:0098656,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.20 ko:K05816 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.3 - iAF1260.b3450,iB21_1397.B21_03252,iBWG_1329.BWG_3141,iECABU_c1320.ECABU_c38800,iECB_1328.ECB_03299,iECDH10B_1368.ECDH10B_3624,iECD_1391.ECD_03299,iETEC_1333.ETEC_3696,iJO1366.b3450,iJR904.b3450,iUMNK88_1353.UMNK88_4218,iY75_1357.Y75_RS19980,ic_1306.c4239 ABC_tran,TOBE_2 DYD1_k127_688611_17 414684.RC1_1522 1.365e-21 103.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,2JPTG@204441|Rhodospirillales 204441|Rhodospirillales Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD1_k127_688611_4 1120960.ATXG01000005_gene2514 3.956e-102 346.0 COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FKZV@85023|Microbacteriaceae 201174|Actinobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD1_k127_688611_13 1226322.HMPREF1545_03117 7.116e-59 220.0 COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes,24BFZ@186801|Clostridia,2N8I4@216572|Oscillospiraceae 186801|Clostridia S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD1_k127_6912471_0 795666.MW7_1558 1.538e-122 409.0 COG2897@1|root,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,2VH3U@28216|Betaproteobacteria,1K1TG@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM Rhodanese domain protein - - - - - - - - - - - - Rhodanese DYD1_k127_6912471_3 1394178.AWOO02000036_gene8905 5.787e-35 140.0 COG5553@1|root,COG5553@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - CDO_I DYD1_k127_6912471_4 768670.Calni_0924 7.047e-20 94.0 COG0589@1|root,COG0589@2|Bacteria,2GFI3@200930|Deferribacteres 200930|Deferribacteres T Universal stress protein family - - - - - - - - - - - - Usp DYD1_k127_6912471_2 1173027.Mic7113_2967 4.646e-76 268.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 2|Bacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_6912471_1 1419583.V466_17620 1.676e-93 309.0 COG0500@1|root,COG0500@2|Bacteria,1R5D7@1224|Proteobacteria,1T1HU@1236|Gammaproteobacteria,1YUJK@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 DYD1_k127_6936170_1 1231391.AMZF01000066_gene1896 1.113e-100 334.0 COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,2VQ0N@28216|Betaproteobacteria,3T4IT@506|Alcaligenaceae 28216|Betaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 DYD1_k127_6936170_0 1231391.AMZF01000066_gene1897 1.352e-228 723.0 COG1021@1|root,COG1021@2|Bacteria,1NSN8@1224|Proteobacteria,2VJ76@28216|Betaproteobacteria,3T20P@506|Alcaligenaceae 28216|Betaproteobacteria Q AMP-binding enzyme C-terminal domain - - 2.7.7.58,6.3.2.14 ko:K02363 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R07644 RC00162,RC03046 ko00000,ko00001,ko01000,ko01008 - - - AMP-binding,AMP-binding_C DYD1_k127_6983897_1 1192034.CAP_3147 3.547e-150 496.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,2YUG5@29|Myxococcales 28221|Deltaproteobacteria L UvrD/REP helicase N-terminal domain - - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C DYD1_k127_6983897_8 1197477.IA57_05550 0.0002252 51.0 COG4772@1|root,COG4772@2|Bacteria,4PKRQ@976|Bacteroidetes,1HX89@117743|Flavobacteriia 976|Bacteroidetes P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3 DYD1_k127_6983897_2 365044.Pnap_0987 1.143e-143 464.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,4AAH8@80864|Comamonadaceae 28216|Betaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD1_k127_6983897_6 349521.HCH_04790 6.548e-30 123.0 COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,1S5YT@1236|Gammaproteobacteria,1XMGB@135619|Oceanospirillales 135619|Oceanospirillales S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K04750 - - - - ko00000 - - - Glyoxalase DYD1_k127_6983897_3 395495.Lcho_0045 2.534e-126 415.0 COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria 28216|Betaproteobacteria T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg DYD1_k127_6983897_5 479434.Sthe_3489 1.517e-103 354.0 COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi 2|Bacteria J PFAM Amidase - - - - - - - - - - - - Amidase,FCD DYD1_k127_6983897_0 522306.CAP2UW1_2481 3.116e-286 905.0 COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2VKJT@28216|Betaproteobacteria 28216|Betaproteobacteria C Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 DYD1_k127_6983897_4 522306.CAP2UW1_2480 1.248e-120 413.0 2B3X8@1|root,31WM6@2|Bacteria,1RFRT@1224|Proteobacteria,2VRRY@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3999) - - - - - - - - - - - - DUF3999 DYD1_k127_6983897_7 716544.wcw_1215 1.408e-08 56.0 COG0729@1|root,COG0729@2|Bacteria,2JFF4@204428|Chlamydiae 204428|Chlamydiae M Surface antigen - - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA DYD1_k127_698950_4 589924.Ferp_2432 6.507e-22 98.0 COG2046@1|root,arCOG04191@2157|Archaea,2XT7C@28890|Euryarchaeota,2464J@183980|Archaeoglobi 183980|Archaeoglobi P sulfate adenylyltransferase sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 DYD1_k127_698950_3 247490.KSU1_C1247 2.127e-63 224.0 COG0529@1|root,COG0529@2|Bacteria,2IYUQ@203682|Planctomycetes 203682|Planctomycetes F Catalyzes the synthesis of activated sulfate cysC - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,PUA_2 DYD1_k127_698950_0 886293.Sinac_2678 1.957e-113 380.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 DYD1_k127_698950_2 886293.Sinac_6605 5.927e-80 280.0 COG0438@1|root,COG0438@2|Bacteria,2J0HS@203682|Planctomycetes 203682|Planctomycetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD1_k127_698950_1 391612.CY0110_22242 8.252e-95 321.0 COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria,3KHCP@43988|Cyanothece 1117|Cyanobacteria M Glycosyl transferase family 21 - - - - - - - - - - - - Glycos_transf_2 DYD1_k127_705401_2 671143.DAMO_0765 2.178e-33 141.0 COG0666@1|root,COG0666@2|Bacteria,2NPRI@2323|unclassified Bacteria 2|Bacteria S Evidence 4 Homologs of previously reported genes of - - - ko:K21440 - - - - ko00000,ko04131 - - - Ank,Ank_2,Ank_4,Ank_5 DYD1_k127_705401_1 436229.JOEH01000051_gene6258 3.198e-50 185.0 29J25@1|root,305ZK@2|Bacteria,2IDE0@201174|Actinobacteria 201174|Actinobacteria S NIPSNAP - - - - - - - - - - - - NIPSNAP DYD1_k127_705401_3 935840.JAEQ01000004_gene646 4.492e-32 138.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_705401_0 717605.Theco_1447 6.145e-103 349.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HBKN@91061|Bacilli,26S3I@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh DYD1_k127_705401_4 1128421.JAGA01000003_gene3292 8.178e-29 119.0 COG0720@1|root,COG0720@2|Bacteria,2NR6T@2323|unclassified Bacteria 2|Bacteria H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS DYD1_k127_709150_0 639283.Snov_0207 5.32e-153 493.0 COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3F1EV@335928|Xanthobacteraceae 28211|Alphaproteobacteria S LVIVD repeat - - - - - - - - - - - - LVIVD DYD1_k127_709150_3 234267.Acid_4282 8.633e-10 65.0 COG5485@1|root,COG5485@2|Bacteria,3Y8NT@57723|Acidobacteria 57723|Acidobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL DYD1_k127_709150_1 1449353.JQMQ01000004_gene6673 9.877e-108 359.0 2EYU0@1|root,33S17@2|Bacteria,2I819@201174|Actinobacteria 201174|Actinobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB DYD1_k127_709150_2 941449.dsx2_2324 3.594e-20 97.0 COG1359@1|root,COG1359@2|Bacteria,1RKQ2@1224|Proteobacteria,43DRE@68525|delta/epsilon subdivisions,2X0VN@28221|Deltaproteobacteria,2MDIH@213115|Desulfovibrionales 28221|Deltaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM DYD1_k127_731011_2 272568.GDI3164 6.298e-10 59.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,2JPS1@204441|Rhodospirillales 204441|Rhodospirillales O Belongs to the GST superfamily - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_N DYD1_k127_731011_1 1095769.CAHF01000011_gene2300 1.782e-144 465.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2W98D@28216|Betaproteobacteria,476N1@75682|Oxalobacteraceae 28216|Betaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - DUF58 DYD1_k127_731011_0 365044.Pnap_3247 1.826e-146 471.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,4ACKS@80864|Comamonadaceae 28216|Betaproteobacteria S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 DYD1_k127_745589_10 671143.DAMO_2862 8.426e-10 60.0 COG0242@1|root,COG0242@2|Bacteria 2|Bacteria J peptide deformylase activity def2 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD1_k127_745589_1 1382356.JQMP01000001_gene1157 2.491e-172 550.0 COG1060@1|root,COG1060@2|Bacteria,2GBD4@200795|Chloroflexi,27YV4@189775|Thermomicrobia 189775|Thermomicrobia H Elongator protein 3, MiaB family, Radical SAM - - 2.5.1.77 ko:K11779 ko00680,ko01120,map00680,map01120 M00378 R09396 RC01381,RC03002,RC03007 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM DYD1_k127_745589_9 667014.Thein_1211 8.067e-21 102.0 2E6CS@1|root,3310E@2|Bacteria,2GH18@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria - - - - - - - - - - - - - - - DYD1_k127_745589_0 335543.Sfum_3302 7.86e-236 744.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2MR5T@213462|Syntrophobacterales 28221|Deltaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon DYD1_k127_745589_2 338963.Pcar_1041 9.171e-148 479.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,43SAP@69541|Desulfuromonadales 28221|Deltaproteobacteria J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD1_k127_745589_8 1121289.JHVL01000062_gene263 1.71e-27 121.0 28PHB@1|root,2ZC7V@2|Bacteria,1V1MY@1239|Firmicutes,24H5K@186801|Clostridia,36IHD@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - DYD1_k127_745589_3 948106.AWZT01000001_gene5077 3.559e-130 433.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2WBWM@28216|Betaproteobacteria,1K6TM@119060|Burkholderiaceae 28216|Betaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - - - - - - - - - - UbiD DYD1_k127_745589_5 1122915.AUGY01000118_gene6533 1.216e-93 317.0 COG0715@1|root,COG0715@2|Bacteria,1VRJ0@1239|Firmicutes,4HV8W@91061|Bacilli,26U3V@186822|Paenibacillaceae 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - DYD1_k127_745589_7 880073.Calab_1106 5.665e-47 174.0 COG2080@1|root,COG2080@2|Bacteria,2NPPX@2323|unclassified Bacteria 2|Bacteria C PFAM 2Fe-2S -binding - - 1.2.5.3,1.3.99.16 ko:K03518,ko:K07302,ko:K13483 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Fer2,Fer2_2,TAT_signal DYD1_k127_745589_6 1231391.AMZF01000004_gene3065 3.727e-55 203.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VSFQ@28216|Betaproteobacteria,3T46Z@506|Alcaligenaceae 28216|Betaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - - - - - - - - - - - CO_deh_flav_C,FAD_binding_5 DYD1_k127_745589_4 1476876.JOJO01000036_gene4375 7.387e-121 415.0 COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria 201174|Actinobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD1_k127_764322_0 1278073.MYSTI_01037 2.07e-172 557.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42PNF@68525|delta/epsilon subdivisions,2WKN3@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q Multicopper oxidase - - 1.16.3.3 ko:K22348 - - - - ko00000,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD1_k127_764322_1 246197.MXAN_3431 2.955e-95 329.0 COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,42UCF@68525|delta/epsilon subdivisions,2WREI@28221|Deltaproteobacteria 28221|Deltaproteobacteria MU Outer membrane efflux protein - - - ko:K15725 - - - - ko00000,ko02000 1.B.17.2.2 - - OEP DYD1_k127_764322_4 401053.AciPR4_2584 4.152e-06 55.0 COG1999@1|root,COG1999@2|Bacteria,3Y5CC@57723|Acidobacteria,2JHX0@204432|Acidobacteriia 204432|Acidobacteriia S Copper binding periplasmic protein CusF - - - ko:K07152 - - - - ko00000,ko03029 - - - CusF_Ec,SCO1-SenC DYD1_k127_764322_2 671143.DAMO_1545 4.138e-28 122.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Cytochrom_C,Cytochrome_CBB3 DYD1_k127_764322_3 671143.DAMO_0003 3.589e-24 104.0 COG0785@1|root,COG0785@2|Bacteria,2NPE4@2323|unclassified Bacteria 2|Bacteria O Cytochrome C biogenesis protein transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD DYD1_k127_76551_17 247490.KSU1_C1261 4.288e-40 156.0 COG2854@1|root,COG2854@2|Bacteria,2J2VT@203682|Planctomycetes 203682|Planctomycetes Q MlaC protein - - - - - - - - - - - - MlaC DYD1_k127_76551_19 291112.PAU_03928 8.694e-30 122.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046473,GO:0046474,GO:0046486,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar DYD1_k127_76551_7 1051632.TPY_2012 1.444e-129 441.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis 186801|Clostridia C Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD1_k127_76551_16 477184.KYC_07590 3.016e-41 162.0 COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2VPUE@28216|Betaproteobacteria,3T4Y2@506|Alcaligenaceae 28216|Betaproteobacteria J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 DYD1_k127_76551_0 330214.NIDE1167 0.0 1431.0 COG1201@1|root,COG1201@2|Bacteria 2|Bacteria L RNA secondary structure unwinding lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C DYD1_k127_76551_20 522306.CAP2UW1_0336 3.429e-10 65.0 29799@1|root,2ZUGZ@2|Bacteria,1P46Y@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_76551_21 1380394.JADL01000001_gene2533 1.79e-08 59.0 294AC@1|root,2ZRQJ@2|Bacteria,1PA56@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_76551_14 56780.SYN_01527 3.507e-75 259.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MQEG@213462|Syntrophobacterales 28221|Deltaproteobacteria U TIGRFAM signal peptidase I lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 DYD1_k127_76551_1 269799.Gmet_1766 2.373e-275 859.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,43UJT@69541|Desulfuromonadales 28221|Deltaproteobacteria J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C DYD1_k127_76551_10 1242864.D187_007540 5.112e-113 375.0 COG0451@1|root,COG0451@2|Bacteria,1QX8V@1224|Proteobacteria,43C1V@68525|delta/epsilon subdivisions,2X5FV@28221|Deltaproteobacteria,2YY2H@29|Myxococcales 28221|Deltaproteobacteria M Polysaccharide biosynthesis protein galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD1_k127_76551_5 518766.Rmar_1858 4.467e-149 477.0 COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M GDP-mannose 4,6 dehydratase - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD1_k127_76551_3 215803.DB30_3219 1.748e-173 554.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2YTZC@29|Myxococcales 28221|Deltaproteobacteria C UDP binding domain ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N DYD1_k127_76551_8 1121403.AUCV01000020_gene3088 5.497e-115 378.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria,2MMID@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyltransferase like family 2 - - 2.4.2.53 ko:K10012 ko00520,ko01503,map00520,map01503 M00721,M00761 R07661 RC00005,RC02954 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.2.1.8 GT2 - Glycos_transf_2 DYD1_k127_76551_9 243231.GSU1113 2.892e-113 380.0 COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales 28221|Deltaproteobacteria H PFAM PfkB domain protein - - - - - - - - - - - iAF987.Gmet_2683 PfkB DYD1_k127_76551_12 1267533.KB906733_gene3460 2.762e-108 357.0 COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia 204432|Acidobacteriia F Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates mtnP - 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 DYD1_k127_76551_13 1123371.ATXH01000018_gene1396 4.533e-95 324.0 COG0820@1|root,COG0820@2|Bacteria,2GGZB@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM DYD1_k127_76551_15 1123368.AUIS01000004_gene260 5.289e-54 192.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,2NCW6@225057|Acidithiobacillales 225057|Acidithiobacillales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK DYD1_k127_76551_6 562970.Btus_1483 1.921e-134 434.0 COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,4HA2J@91061|Bacilli,2792C@186823|Alicyclobacillaceae 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA DYD1_k127_76551_4 796606.BMMGA3_06055 2.494e-161 517.0 COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU16090 ATP-grasp_2,Ligase_CoA DYD1_k127_76551_11 370438.PTH_1367 4.414e-111 367.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,260EM@186807|Peptococcaceae 186801|Clostridia C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N DYD1_k127_76551_2 1192034.CAP_3742 8.665e-211 665.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales 28221|Deltaproteobacteria C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD1_k127_76551_18 1123392.AQWL01000003_gene190 8.568e-33 137.0 COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2VUZW@28216|Betaproteobacteria 28216|Betaproteobacteria M PFAM Conserved TM helix - - - - - - - - - - - - TM_helix DYD1_k127_76551_22 930171.Asphe3_10610 2.613e-08 56.0 COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria 201174|Actinobacteria G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K10441,ko:K10562 ko02010,map02010 M00212,M00220 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9 - - ABC_tran DYD1_k127_785822_3 1123376.AUIU01000016_gene232 7.311e-14 80.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - FKBP_C,FKBP_N DYD1_k127_785822_2 1123376.AUIU01000016_gene231 2.938e-31 138.0 COG5002@1|root,COG5002@2|Bacteria,3J10G@40117|Nitrospirae 40117|Nitrospirae T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD1_k127_785822_1 395965.Msil_1885 3.382e-56 222.0 COG0642@1|root,COG2972@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria,3N9SQ@45404|Beijerinckiaceae 28211|Alphaproteobacteria T GAF domain - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1 DYD1_k127_785822_0 1134413.ANNK01000086_gene318 2.204e-91 310.0 COG0715@1|root,COG0715@2|Bacteria,1TXP3@1239|Firmicutes,4I6PJ@91061|Bacilli,1ZM9Z@1386|Bacillus 91061|Bacilli P NMT1/THI5 like - - - - - - - - - - - - NMT1 DYD1_k127_7957_0 1231391.AMZF01000063_gene1102 7.178e-126 422.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_7957_3 1231391.AMZF01000068_gene2180 4.686e-36 150.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_7957_1 264198.Reut_B5286 6.379e-63 229.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP7Y@28216|Betaproteobacteria,1KBE5@119060|Burkholderiaceae 28216|Betaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_7957_2 439235.Dalk_2665 1.489e-43 172.0 COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD1_k127_823839_2 1304885.AUEY01000073_gene1472 4.044e-30 125.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,2MK5K@213118|Desulfobacterales 28221|Deltaproteobacteria S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd DYD1_k127_823839_1 269799.Gmet_3422 1.49e-131 437.0 COG2812@1|root,COG3266@1|root,COG2812@2|Bacteria,COG3266@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,43T4B@69541|Desulfuromonadales 28221|Deltaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 DYD1_k127_823839_0 596152.DesU5LDRAFT_0535 1.37e-202 650.0 COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales 28221|Deltaproteobacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 DYD1_k127_82568_8 1267533.KB906733_gene3312 1.273e-05 59.0 COG2982@1|root,COG2982@2|Bacteria,3Y2J8@57723|Acidobacteria,2JKPW@204432|Acidobacteriia 204432|Acidobacteriia M Protein involved in outer membrane biogenesis - - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2,DUF748 DYD1_k127_82568_0 1157490.EL26_23155 4.352e-162 519.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,277YV@186823|Alicyclobacillaceae 91061|Bacilli I Belongs to the thiolase family pcaF - 2.3.1.174,2.3.1.223,2.3.1.9 ko:K00626,ko:K02615 ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R00829,R01177,R09839 RC00004,RC00326,RC03003 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD1_k127_82568_4 1118054.CAGW01000061_gene2433 1.998e-62 223.0 COG1250@1|root,COG1250@2|Bacteria,1TSZI@1239|Firmicutes,4HBK3@91061|Bacilli,26UKH@186822|Paenibacillaceae 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - 3HCDH,3HCDH_N DYD1_k127_82568_1 292459.STH214 1.78e-96 324.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 186801|Clostridia I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 ko:K00074,ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N DYD1_k127_82568_3 644966.Tmar_2131 1.868e-87 295.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,24HM8@186801|Clostridia,3WDT7@538999|Clostridiales incertae sedis 186801|Clostridia I Belongs to the enoyl-CoA hydratase isomerase family - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 DYD1_k127_82568_2 1124780.ANNU01000058_gene886 4.044e-88 297.0 COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692,ko:K01715 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD1_k127_82568_6 1379698.RBG1_1C00001G0893 3.729e-38 151.0 COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria 2|Bacteria K Bacterial regulatory proteins, tetR family - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_4,TetR_N DYD1_k127_82568_5 247490.KSU1_C0935 1.519e-52 190.0 COG0450@1|root,COG0450@2|Bacteria,2IZ3M@203682|Planctomycetes 203682|Planctomycetes O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA DYD1_k127_82568_7 671143.DAMO_1602 8.854e-26 118.0 COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria 2|Bacteria S VIT family MA20_19235 - - - - - - - - - - - Rubrerythrin,VIT1 DYD1_k127_829419_1 398578.Daci_5631 4.733e-193 614.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VITF@28216|Betaproteobacteria,4ABU5@80864|Comamonadaceae 28216|Betaproteobacteria EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B DYD1_k127_829419_0 543728.Vapar_5966 1.082e-228 727.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,4AAHY@80864|Comamonadaceae 28216|Betaproteobacteria EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A DYD1_k127_829419_3 203119.Cthe_1570 4.043e-06 58.0 COG0715@1|root,COG0715@2|Bacteria,1V0KP@1239|Firmicutes,25B6E@186801|Clostridia,3WIJG@541000|Ruminococcaceae 186801|Clostridia P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_829419_2 76869.PputGB1_0536 3.55e-52 192.0 COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,1RN73@1236|Gammaproteobacteria,1YXHI@136845|Pseudomonas putida group 1236|Gammaproteobacteria J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - iECP_1309.ECP_3693,iSbBS512_1146.SbBS512_E4006 Se-cys_synth_N,SelA DYD1_k127_85383_0 324602.Caur_3201 0.0 1309.0 COG0243@1|root,COG0243@2|Bacteria,2G5ZB@200795|Chloroflexi,37670@32061|Chloroflexia 32061|Chloroflexia C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD1_k127_85383_1 309801.trd_A0629 5.769e-158 516.0 COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi 200795|Chloroflexi C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - - - - - - - - - - Fer4_11,NrfD DYD1_k127_85383_4 649747.HMPREF0083_05444 5.012e-39 154.0 COG5424@1|root,COG5424@2|Bacteria,1VNTM@1239|Firmicutes,4HSNP@91061|Bacilli,26WCG@186822|Paenibacillaceae 91061|Bacilli H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2 DYD1_k127_85383_2 1160137.KB907307_gene2603 9.041e-103 355.0 COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria,4FZAK@85025|Nocardiaceae 201174|Actinobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6,4.1.1.7 ko:K01576,ko:K01652 ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648 RC00027,RC00106,RC00595,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD1_k127_85383_3 262316.MAP_1627 7.274e-61 222.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae 201174|Actinobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_877873_1 765420.OSCT_2153 7.771e-11 73.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_877873_0 935840.JAEQ01000004_gene641 8.93e-126 417.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,43HM4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria EQ N-methylhydantoinase A acetone carboxylase, beta subunit - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A DYD1_k127_881973_8 1122221.JHVI01000003_gene405 0.0003365 45.0 COG2095@1|root,COG2095@2|Bacteria,1WJXY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus U UPF0056 membrane protein marC - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD1_k127_881973_0 1173027.Mic7113_5585 2.075e-167 535.0 COG1252@1|root,COG1252@2|Bacteria,1G20T@1117|Cyanobacteria,1H80B@1150|Oscillatoriales 1117|Cyanobacteria C NADH dehydrogenase, FAD-containing subunit ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD1_k127_881973_2 118163.Ple7327_4329 1.234e-75 263.0 COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,3VIED@52604|Pleurocapsales 1117|Cyanobacteria S PFAM Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 DYD1_k127_881973_4 1408254.T458_00670 2.877e-52 198.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,26W4T@186822|Paenibacillaceae 91061|Bacilli C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD1_k127_881973_3 1463936.JOJI01000029_gene3267 9.814e-56 209.0 COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria 201174|Actinobacteria S Pfam Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD1_k127_881973_6 667632.KB890169_gene5065 5.678e-12 76.0 COG0715@1|root,COG0715@2|Bacteria,1R3SJ@1224|Proteobacteria,2VMUC@28216|Betaproteobacteria,1K1MD@119060|Burkholderiaceae 28216|Betaproteobacteria P Nitrate ABC transporter substrate-binding protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_881973_7 1449063.JMLS01000027_gene61 6.042e-12 76.0 COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,26UYR@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_881973_5 1502724.FF80_02470 5.562e-16 91.0 COG1840@1|root,COG1840@2|Bacteria,1N1D3@1224|Proteobacteria,2UKZ7@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_6 DYD1_k127_881973_1 1502724.FF80_02474 9.505e-100 342.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD1_k127_882290_2 1123508.JH636442_gene4220 9.847e-185 596.0 COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes 203682|Planctomycetes L DEAD DEAH box helicase - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind DYD1_k127_882290_5 522306.CAP2UW1_1735 1.824e-60 217.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,2VJYK@28216|Betaproteobacteria,1KQWP@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Lactamase_B,Rhodanese DYD1_k127_882290_7 443152.MDG893_15090 1.18e-30 128.0 2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,1SP86@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_882290_6 383372.Rcas_4187 9.676e-42 158.0 COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi,375VA@32061|Chloroflexia 32061|Chloroflexia S PFAM flavin reductase domain protein, FMN-binding - - - - - - - - - - - - Flavin_Reduct DYD1_k127_882290_8 1120933.ATUY01000015_gene1570 5.723e-18 91.0 COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4D3VD@85005|Actinomycetales 201174|Actinobacteria K Transcriptional regulator merR2 - - - - - - - - - - - MerR_1 DYD1_k127_882290_0 316067.Geob_2761 1.143e-261 831.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales 28221|Deltaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V DYD1_k127_882290_3 96561.Dole_1127 2.313e-91 316.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2MHPG@213118|Desulfobacterales 28221|Deltaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,TPR_6 DYD1_k127_882290_1 243231.GSU1820 4.047e-218 707.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales 28221|Deltaproteobacteria H Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2 DYD1_k127_882290_4 555079.Toce_1271 6.172e-76 269.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,42FSH@68295|Thermoanaerobacterales 186801|Clostridia L integrase domain protein SAM domain protein xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD1_k127_883511_6 1226994.AMZB01000111_gene1936 0.0003196 46.0 COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,1YGXI@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Belongs to the UPF0337 (CsbD) family yjbJ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - CsbD DYD1_k127_883511_4 1121921.KB898706_gene2831 1.968e-13 76.0 COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,1S2G2@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Bacterioferritin IV02_12050 - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin DYD1_k127_883511_2 296591.Bpro_2306 8.632e-51 183.0 COG5478@1|root,COG5478@2|Bacteria,1MZMZ@1224|Proteobacteria,2VV6G@28216|Betaproteobacteria,4AFCR@80864|Comamonadaceae 28216|Betaproteobacteria S Low affinity iron permease - - - - - - - - - - - - Iron_permease DYD1_k127_883511_3 204669.Acid345_3970 1.561e-28 121.0 2DQJB@1|root,3377V@2|Bacteria,3Y8JD@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - DYD1_k127_883511_5 264462.Bd1528 2.226e-08 58.0 2EMKC@1|root,33F8T@2|Bacteria,1NP5C@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_883511_1 1173028.ANKO01000077_gene5317 2.88e-88 305.0 COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Ribonuclease BN-like family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB DYD1_k127_883511_0 261292.Nit79A3_2282 7.939e-101 343.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2VHC0@28216|Betaproteobacteria,373MJ@32003|Nitrosomonadales 28216|Betaproteobacteria S Pfam:UPF0118 - - - - - - - - - - - - AI-2E_transport,GAF,GAF_2 DYD1_k127_8850_2 631454.N177_2292 1.577e-68 238.0 COG0600@1|root,COG0600@2|Bacteria,1R9SQ@1224|Proteobacteria,2V8Z7@28211|Alphaproteobacteria,1JQBN@119043|Rhodobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 DYD1_k127_8850_1 649638.Trad_0627 7.586e-96 319.0 COG1116@1|root,COG1116@2|Bacteria,1WJMK@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD1_k127_8850_0 631454.N177_2294 1.827e-111 371.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - - - - - - - - - - NMT1 DYD1_k127_886279_7 1123376.AUIU01000016_gene234 5.799e-15 78.0 COG2823@1|root,COG2823@2|Bacteria 2|Bacteria S hyperosmotic response - - - ko:K04065 - - - - ko00000 - - - BON DYD1_k127_886279_8 1211115.ALIQ01000052_gene2851 6.569e-08 55.0 2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF3096) - - - - - - - - - - - - DUF3096 DYD1_k127_886279_6 251221.35211903 6.633e-18 92.0 COG4783@1|root,COG4783@2|Bacteria,1G1TE@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD1_k127_886279_5 1500897.JQNA01000002_gene1532 4.78e-26 112.0 COG0642@1|root,COG0745@1|root,COG1352@1|root,COG0745@2|Bacteria,COG1352@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,1JZSA@119060|Burkholderiaceae 28216|Betaproteobacteria T catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_4,Response_reg DYD1_k127_886279_4 207559.Dde_0519 2.496e-36 145.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2WMCA@28221|Deltaproteobacteria,2MBVF@213115|Desulfovibrionales 28221|Deltaproteobacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR DYD1_k127_886279_2 671143.DAMO_1116 4.397e-62 226.0 COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria 2|Bacteria M Mannose-6-phosphate isomerase manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase DYD1_k127_886279_1 404589.Anae109_1904 5.922e-67 234.0 COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N DYD1_k127_886279_0 880073.Calab_3404 4.403e-141 462.0 COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria 2|Bacteria T Two component, sigma54 specific, transcriptional regulator, Fis family - - - ko:K02667,ko:K07714 ko02020,map02020 M00500,M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat DYD1_k127_886279_3 237368.SCABRO_01854 5.596e-46 184.0 COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2IXFD@203682|Planctomycetes 203682|Planctomycetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg DYD1_k127_915268_10 1120972.AUMH01000030_gene966 4.116e-51 192.0 COG3435@1|root,COG3435@2|Bacteria,1UYG0@1239|Firmicutes,4HCWV@91061|Bacilli,278ZZ@186823|Alicyclobacillaceae 91061|Bacilli Q Cupin domain - - 1.13.11.4 ko:K00450 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R02656 RC00764 ko00000,ko00001,ko01000 - - - Cupin_2 DYD1_k127_915268_5 593117.TGAM_1014 3.552e-93 319.0 COG3839@1|root,arCOG00175@2157|Archaea,2Y7MB@28890|Euryarchaeota 28890|Euryarchaeota E PFAM ABC transporter - - 3.6.3.29,3.6.3.30 ko:K02010,ko:K02017,ko:K02062,ko:K10112,ko:K10199,ko:K17314 ko02010,map02010 M00189,M00190,M00191,M00194,M00196,M00197,M00200,M00201,M00203,M00206,M00207,M00491,M00602,M00604,M00605,M00606 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.13,3.A.1.1.14,3.A.1.1.15,3.A.1.10,3.A.1.19,3.A.1.8 - - ABC_tran,TOBE_2 DYD1_k127_915268_12 1532558.JL39_06940 5.985e-20 103.0 COG1840@1|root,COG1840@2|Bacteria,1PGNJ@1224|Proteobacteria,2V7JA@28211|Alphaproteobacteria,4BDDZ@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 DYD1_k127_915268_9 1321781.HMPREF1985_01679 7.37e-57 202.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4H4EU@909932|Negativicutes 909932|Negativicutes O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB DYD1_k127_915268_11 555779.Dthio_PD2300 5.399e-46 175.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,42S5R@68525|delta/epsilon subdivisions,2WNM7@28221|Deltaproteobacteria,2MB5T@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 DYD1_k127_915268_4 96561.Dole_0042 1.011e-93 315.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2WJ19@28221|Deltaproteobacteria,2MHRN@213118|Desulfobacterales 28221|Deltaproteobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase DYD1_k127_915268_3 269799.Gmet_1642 1.358e-102 340.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,43S2A@69541|Desulfuromonadales 28221|Deltaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf DYD1_k127_915268_6 290397.Adeh_3683 9.685e-71 244.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria 1224|Proteobacteria F Deoxynucleoside kinase dgk - - - - - - - - - - - dNK DYD1_k127_915268_2 335543.Sfum_0447 2.153e-147 486.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MRU@68525|delta/epsilon subdivisions,2WIQX@28221|Deltaproteobacteria 28221|Deltaproteobacteria MU TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - - - - - - - - - - OEP DYD1_k127_915268_0 706587.Desti_1032 0.0 1695.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria 28221|Deltaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD1_k127_915268_1 706587.Desti_1031 1.454e-159 511.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585,ko:K07799 ko01501,ko01503,ko02020,map01501,map01503,map02020 M00646,M00647,M00648,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1,8.A.1.6 - - HlyD_D23 DYD1_k127_915268_8 1123242.JH636435_gene1758 2.326e-58 210.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator MA20_16815 - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N DYD1_k127_915268_7 1123393.KB891316_gene1263 9.147e-59 212.0 293J8@1|root,2ZR19@2|Bacteria,1R6Y4@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD1_k127_919343_1 443152.MDG893_15467 3.353e-55 207.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_919343_2 443152.MDG893_15295 6.436e-50 191.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_919343_0 443152.MDG893_15260 9.869e-57 211.0 COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD1_k127_919343_3 1144310.PMI07_005585 4.47e-23 111.0 COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae 1224|Proteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_930510_7 640512.BC1003_0769 0.0005679 45.0 COG0451@1|root,COG0451@2|Bacteria,1NRK1@1224|Proteobacteria,2VKDT@28216|Betaproteobacteria,1K1E5@119060|Burkholderiaceae 28216|Betaproteobacteria M PFAM NAD-dependent epimerase dehydratase - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD1_k127_930510_2 795797.C497_07249 4.804e-49 188.0 COG2141@1|root,arCOG02410@2157|Archaea,2XT6F@28890|Euryarchaeota,23TX5@183963|Halobacteria 183963|Halobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD1_k127_930510_1 1231391.AMZF01000046_gene961 3.273e-50 192.0 COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD1_k127_930510_6 526227.Mesil_1124 3.869e-20 98.0 COG1335@1|root,COG1335@2|Bacteria,1WIVK@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus Q PFAM Isochorismatase family - - - - - - - - - - - - Isochorismatase DYD1_k127_930510_0 543728.Vapar_1913 3.328e-110 373.0 COG2159@1|root,COG2159@2|Bacteria,1R7D7@1224|Proteobacteria,2VNK3@28216|Betaproteobacteria,4AHCY@80864|Comamonadaceae 28216|Betaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_930510_4 1550073.JROH01000005_gene1600 2.496e-26 116.0 COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TSFM@28211|Alphaproteobacteria,2K0VD@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 DYD1_k127_930510_3 710686.Mycsm_01832 2.661e-44 174.0 COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria 201174|Actinobacteria S NMT1-like family - - - - - - - - - - - - NMT1_3 DYD1_k127_930510_5 107636.JQNK01000005_gene1002 2.996e-22 99.0 COG3636@1|root,COG3636@2|Bacteria,1N0RK@1224|Proteobacteria,2UDN3@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - - DYD1_k127_930624_1 1134413.ANNK01000100_gene750 1.083e-35 154.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA DYD1_k127_930624_0 1125863.JAFN01000001_gene1095 8.528e-45 171.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria 28221|Deltaproteobacteria K response regulator - - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg DYD1_k127_930624_3 1123366.TH3_10176 4.402e-09 59.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,2JS6P@204441|Rhodospirillales 204441|Rhodospirillales O Redoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD1_k127_930624_4 330779.Saci_1125 6.305e-07 55.0 COG1225@1|root,arCOG00310@2157|Archaea,2XQPI@28889|Crenarchaeota 28889|Crenarchaeota O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD1_k127_930624_2 1123073.KB899242_gene1596 4.459e-12 72.0 COG3909@1|root,COG3909@2|Bacteria,1N1E5@1224|Proteobacteria,1SB46@1236|Gammaproteobacteria,1XCP2@135614|Xanthomonadales 1236|Gammaproteobacteria C Cytochrome C' - - - - - - - - - - - - Cytochrom_C_2 DYD1_k127_942713_1 1238182.C882_2113 4.606e-17 86.0 COG5455@1|root,COG5455@2|Bacteria,1N3PU@1224|Proteobacteria,2UGK9@28211|Alphaproteobacteria,2JUR7@204441|Rhodospirillales 204441|Rhodospirillales S response to cobalt ion - - - - - - - - - - - - - DYD1_k127_942713_0 1207076.ALAT01000184_gene2654 5.026e-29 124.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1Z05X@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD1_k127_942713_3 1047013.AQSP01000098_gene2563 7.54e-05 52.0 2APP3@1|root,31ESP@2|Bacteria,2NS0G@2323|unclassified Bacteria 2|Bacteria S Putative zinc-finger - - - - - - - - - - - - zf-HC2 DYD1_k127_942713_2 582744.Msip34_0235 5.244e-07 56.0 2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,2KN10@206350|Nitrosomonadales 206350|Nitrosomonadales S Protein of unknown function (DUF3106) - - - - - - - - - - - - DUF3106 DYD1_k127_947639_0 189753.AXAS01000041_gene2534 3.172e-92 313.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD1_k127_947639_5 1254432.SCE1572_33465 8.523e-54 196.0 COG0819@1|root,COG0819@2|Bacteria 2|Bacteria K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 DYD1_k127_947639_3 572546.Arcpr_0691 1.009e-73 259.0 COG0111@1|root,COG0440@1|root,arCOG01754@2157|Archaea,arCOG04445@2157|Archaea,2XU9V@28890|Euryarchaeota,246MG@183980|Archaeoglobi 183980|Archaeoglobi E D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT DYD1_k127_947639_8 1120949.KB903357_gene5007 4.464e-26 117.0 COG0420@1|root,COG0420@2|Bacteria 2|Bacteria L 3'-5' exonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C DYD1_k127_947639_9 290397.Adeh_1893 1.395e-15 78.0 2CFNS@1|root,331AJ@2|Bacteria,1NBYG@1224|Proteobacteria,42VZ5@68525|delta/epsilon subdivisions,2WR8A@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD1_k127_947639_1 479434.Sthe_3474 1.058e-74 265.0 COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi,27XRM@189775|Thermomicrobia 189775|Thermomicrobia S Amidohydrolase family - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 DYD1_k127_947639_7 1042877.GQS_03845 2.88e-33 140.0 COG1073@1|root,arCOG01651@2157|Archaea,2XUHY@28890|Euryarchaeota,2430A@183968|Thermococci 183968|Thermococci S Alpha beta superfamily - - - - - - - - - - - - Hydrolase_4,Peptidase_S15 DYD1_k127_947639_6 118168.MC7420_6291 2.612e-40 162.0 COG3221@1|root,COG3221@2|Bacteria,1G2AZ@1117|Cyanobacteria,1HAC9@1150|Oscillatoriales 1117|Cyanobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd DYD1_k127_947639_11 1532558.JL39_00915 0.000695 46.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD1_k127_947639_4 1121396.KB892935_gene3861 1.706e-67 246.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales 28221|Deltaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD1_k127_947639_2 350054.Mflv_0673 1.259e-74 262.0 COG0329@1|root,COG0329@2|Bacteria,2HN4J@201174|Actinobacteria,23EW4@1762|Mycobacteriaceae 201174|Actinobacteria EM PFAM Dihydrodipicolinate synthetase - - 4.1.2.34 ko:K11946,ko:K11949 ko00624,ko01100,ko01120,ko01220,map00624,map01100,map01120,map01220 - R05648,R07713 RC00924,RC00936 ko00000,ko00001,ko01000 - - - DHDPS DYD1_k127_947639_10 1424334.W822_07390 2.442e-13 81.0 COG0715@1|root,COG0715@2|Bacteria,1MVUJ@1224|Proteobacteria,2W9A2@28216|Betaproteobacteria,3T6BS@506|Alcaligenaceae 28216|Betaproteobacteria P Substrate binding domain of ABC-type glycine betaine transport system - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD1_k127_96923_1 861299.J421_3613 3.986e-303 943.0 COG3808@1|root,COG3808@2|Bacteria,1ZT09@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase DYD1_k127_96923_10 555779.Dthio_PD2456 1.438e-56 207.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2M9RT@213115|Desulfovibrionales 28221|Deltaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC DYD1_k127_96923_19 882.DVU_1896 6.438e-10 64.0 COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,2MD9B@213115|Desulfovibrionales 28221|Deltaproteobacteria J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p DYD1_k127_96923_17 1232410.KI421413_gene802 3.815e-18 92.0 COG2980@1|root,COG2980@2|Bacteria,1NIUQ@1224|Proteobacteria,42XGJ@68525|delta/epsilon subdivisions,2WSS7@28221|Deltaproteobacteria,43V49@69541|Desulfuromonadales 28221|Deltaproteobacteria M Lipopolysaccharide-assembly lptE - - - - - - - - - - - LptE DYD1_k127_96923_0 1232410.KI421413_gene803 0.0 1159.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,43RYY@69541|Desulfuromonadales 28221|Deltaproteobacteria J Leucyl-tRNA synthetase, Domain 2 leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_2300 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 DYD1_k127_96923_14 439235.Dalk_3316 2.252e-35 141.0 COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2MK59@213118|Desulfobacterales 28221|Deltaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB DYD1_k127_96923_11 1123325.JHUV01000002_gene125 1.448e-55 201.0 COG0054@1|root,COG0054@2|Bacteria,2G3YV@200783|Aquificae 200783|Aquificae H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase DYD1_k127_96923_3 589865.DaAHT2_1277 1.183e-140 458.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MIF1@213118|Desulfobacterales 28221|Deltaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 DYD1_k127_96923_12 243231.GSU1689 6.559e-55 198.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,43UMU@69541|Desulfuromonadales 28221|Deltaproteobacteria H Lumazine binding domain ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding DYD1_k127_96923_6 642492.Clole_2717 3.651e-105 356.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia 186801|Clostridia H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 DYD1_k127_96923_9 398767.Glov_1748 4.956e-59 208.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone DYD1_k127_96923_2 443143.GM18_3073 1.349e-193 611.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43U6J@69541|Desulfuromonadales 28221|Deltaproteobacteria F Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT DYD1_k127_96923_15 1278073.MYSTI_05227 3.196e-25 106.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria 28221|Deltaproteobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD1_k127_96923_8 1122947.FR7_3310 8.081e-84 286.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes 909932|Negativicutes IQ reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD1_k127_96923_5 1232410.KI421413_gene692 7.545e-106 351.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales 28221|Deltaproteobacteria I TIGRFAM malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 DYD1_k127_96923_4 1125863.JAFN01000001_gene40 6.483e-107 358.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2WIXX@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis DYD1_k127_96923_18 1340493.JNIF01000004_gene722 3.211e-16 79.0 COG0333@1|root,COG0333@2|Bacteria,3Y5W0@57723|Acidobacteria 57723|Acidobacteria J Ribosomal L32p protein family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p DYD1_k127_96923_16 1267533.KB906734_gene4286 1.599e-21 100.0 COG1399@1|root,COG1399@2|Bacteria,3Y4KJ@57723|Acidobacteria,2JJ8Y@204432|Acidobacteriia 204432|Acidobacteriia S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 DYD1_k127_96923_7 243231.GSU0367 6.54e-95 321.0 COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2WIPW@28221|Deltaproteobacteria,43TZ7@69541|Desulfuromonadales 28221|Deltaproteobacteria S SMART Elongator protein 3 MiaB NifB yhcC-1 - - ko:K07139 - - - - ko00000 - - - Radical_SAM,Radical_SAM_C DYD1_k127_96923_13 1499967.BAYZ01000147_gene719 2.567e-45 176.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity MA20_20705 - 3.4.21.107 ko:K04691,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD1_k127_989357_3 1123368.AUIS01000024_gene953 6.995e-25 107.0 COG2890@1|root,COG2890@2|Bacteria,1MY5I@1224|Proteobacteria,1T26C@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase (PrmA) - - - - - - - - - - - - Methyltransf_31,PrmA DYD1_k127_989357_0 1088721.NSU_2307 4.177e-53 203.0 COG2159@1|root,COG2159@2|Bacteria,1N5TN@1224|Proteobacteria,2UE32@28211|Alphaproteobacteria,2K8SV@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD1_k127_989357_1 204669.Acid345_4783 2.942e-31 132.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - - - - - - - - - - - AhpC-TSA,Rhodanese,Thioredoxin_8 DYD1_k127_989357_4 1122915.AUGY01000118_gene6536 1.489e-23 114.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae 91061|Bacilli P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 DYD1_k127_989357_2 710686.Mycsm_01832 4.966e-31 129.0 COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria 201174|Actinobacteria S NMT1-like family - - - - - - - - - - - - NMT1_3 ## 4496 queries scanned ## Total time (seconds): 24.932157516479492 ## Rate: 180.33 q/s