## Sun Mar 16 10:05:07 2025 ## emapper-2.1.9 ## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD2_bin.13.fa -m mmseqs --itype genome -o DYD2_bin.13 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD2_bin.13 --cpu 8 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs DYD2_k127_1003666_19 765912.Thimo_2633 1.729e-82 277.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1WX4Z@135613|Chromatiales 135613|Chromatiales S AI-2E family transporter - - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport DYD2_k127_1003666_34 1207063.P24_06746 6.319e-59 216.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,2JPKA@204441|Rhodospirillales 204441|Rhodospirillales GM NmrA-like family - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind DYD2_k127_1003666_28 1117379.BABA_13707 2.356e-70 250.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis tlpA - - - - - - - - - - - Redoxin,Thioredoxin_8 DYD2_k127_1003666_45 1380393.JHVP01000004_gene562 1.234e-10 66.0 2BZD4@1|root,33Y08@2|Bacteria,2GY7R@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD2_k127_1003666_44 228405.HNE_2485 1.984e-11 66.0 2E6FA@1|root,3312Q@2|Bacteria,1NCPQ@1224|Proteobacteria,2UKWD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_1003666_18 375286.mma_1852 4.939e-84 289.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4731A@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_1003666_26 1231391.AMZF01000018_gene1862 5.471e-71 254.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria 28216|Betaproteobacteria C acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_1003666_36 999630.TUZN_2066 4.721e-52 199.0 COG1064@1|root,arCOG01455@2157|Archaea,2XQ4K@28889|Crenarchaeota 28889|Crenarchaeota C Alcohol dehydrogenase zinc-binding domain protein - - 1.1.1.1 ko:K13953,ko:K18382 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703 RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_1003666_20 748247.AZKH_0540 4.043e-81 279.0 COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2VMAI@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 DYD2_k127_1003666_12 748247.AZKH_0539 5.955e-99 331.0 COG5486@1|root,COG5486@2|Bacteria,1R6FN@1224|Proteobacteria,2VMCU@28216|Betaproteobacteria 28216|Betaproteobacteria S Predicted metal-binding integral membrane protein (DUF2182) - - - - - - - - - - - - DUF2182 DYD2_k127_1003666_8 886293.Sinac_3820 1.701e-142 460.0 COG2141@1|root,COG2141@2|Bacteria,2J10P@203682|Planctomycetes 203682|Planctomycetes C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD2_k127_1003666_23 1394178.AWOO02000022_gene7157 3.128e-76 270.0 COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria,4EHI5@85012|Streptosporangiales 201174|Actinobacteria H Ketopantoate reductase PanE/ApbA C terminal - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C DYD2_k127_1003666_42 1122214.AQWH01000003_gene3922 2.061e-13 82.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria 1224|Proteobacteria P ABC-type Fe3 transport system, periplasmic component - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 DYD2_k127_1003666_11 1120983.KB894572_gene2920 2.612e-112 384.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,1JQ5J@119043|Rhodobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD2_k127_1003666_15 1262914.BN533_01824 5.952e-90 308.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H2BP@909932|Negativicutes 909932|Negativicutes P Belongs to the ABC transporter superfamily - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 DYD2_k127_1003666_13 246969.TAM4_600 2.682e-92 320.0 COG3839@1|root,arCOG00177@2157|Archaea,2XTU1@28890|Euryarchaeota 28890|Euryarchaeota E COG3842 ABC-type spermidine putrescine transport systems, ATPase components - - 3.6.3.29,3.6.3.30,3.6.3.55 ko:K02010,ko:K02017,ko:K15497 ko02010,map02010 M00189,M00190,M00423 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.5,3.A.1.8 - - ABC_tran,TOBE,TOBE_2 DYD2_k127_1003666_21 631454.N177_2967 3.987e-78 274.0 COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,2VFXG@28211|Alphaproteobacteria 28211|Alphaproteobacteria CE Dehydrogenase - GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.42,1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 ko:K00031,ko:K00052,ko:K07246 ko00020,ko00290,ko00480,ko00630,ko00650,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00630,map00650,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00432,M00535,M00740 R00215,R00267,R00268,R00994,R01751,R01899,R02545,R04426,R06180,R10052 RC00001,RC00084,RC00105,RC00114,RC00417,RC00594,RC00626,RC02801,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD2_k127_1003666_32 29306.JOBE01000001_gene2652 1.717e-66 242.0 COG2267@1|root,COG2267@2|Bacteria,2I9TP@201174|Actinobacteria 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_1003666_37 1255043.TVNIR_0462 1.841e-48 181.0 COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria,1WZFF@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 DYD2_k127_1003666_0 1038858.AXBA01000011_gene1454 4.346e-254 794.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the UbiD family - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD2_k127_1003666_25 1121106.JQKB01000011_gene390 7.516e-72 250.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,2JVKT@204441|Rhodospirillales 204441|Rhodospirillales K Sir2 family - - - - - - - - - - - - SIR2 DYD2_k127_1003666_17 388051.AUFE01000048_gene2421 5.92e-88 304.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM0F@28216|Betaproteobacteria 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_1003666_27 1370122.JHXQ01000033_gene377 1.642e-70 259.0 COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,4BGVS@82115|Rhizobiaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase of unknown function (DUF1100) - - - - - - - - - - - - Abhydrolase_6,DUF1100,Peptidase_S9 DYD2_k127_1003666_33 1157708.KB907457_gene2657 1.044e-61 225.0 COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2VJFW@28216|Betaproteobacteria,4ACG6@80864|Comamonadaceae 28216|Betaproteobacteria H Ketopantoate reductase PanE/ApbA C terminal panE - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C DYD2_k127_1003666_24 1123060.JONP01000007_gene4984 4.342e-72 254.0 COG0596@1|root,COG0596@2|Bacteria,1R9EZ@1224|Proteobacteria,2U44G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_1003666_46 1408473.JHXO01000002_gene3952 0.0003512 47.0 COG0347@1|root,COG0347@2|Bacteria,4NSBG@976|Bacteroidetes,2FT39@200643|Bacteroidia 976|Bacteroidetes E COG NOG19114 non supervised orthologous group - - - - - - - - - - - - - DYD2_k127_1003666_39 420324.KI911952_gene3300 1.194e-42 160.0 COG0457@1|root,COG0457@2|Bacteria,1N6TJ@1224|Proteobacteria,2UG5W@28211|Alphaproteobacteria,1JYPC@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_8 DYD2_k127_1003666_41 631454.N177_4032 6.391e-39 149.0 COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Thioesterase - - - - - - - - - - - - 4HBT DYD2_k127_1003666_9 1163617.SCD_n00016 3.697e-126 409.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria 28216|Betaproteobacteria NU NYN domain - - - - - - - - - - - - NYN,OST-HTH DYD2_k127_1003666_16 1163617.SCD_n02203 4.162e-89 302.0 COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,2VQJE@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA nfi - 3.1.21.7 ko:K05982 - - - - ko00000,ko01000,ko03400 - - - Endonuclease_5 DYD2_k127_1003666_22 296591.Bpro_2641 5.846e-78 266.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae 28216|Betaproteobacteria O protein-L-isoaspartate O-methyltransferase pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD2_k127_1003666_35 1122212.AULO01000014_gene1157 5.104e-56 207.0 COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,1RYIU@1236|Gammaproteobacteria,1XKCX@135619|Oceanospirillales 135619|Oceanospirillales T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - FHA,Guanylate_cyc DYD2_k127_1003666_29 99598.Cal7507_2327 1.395e-69 247.0 COG2084@1|root,COG2084@2|Bacteria,1GFKR@1117|Cyanobacteria,1HMUH@1161|Nostocales 1117|Cyanobacteria I Domain of unknown function (DUF1932) - - - - - - - - - - - - DUF1932,NAD_binding_2 DYD2_k127_1003666_14 1231391.AMZF01000094_gene118 2.034e-90 311.0 COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria 28216|Betaproteobacteria EGP major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_1003666_1 1123504.JQKD01000005_gene4907 2.575e-218 692.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,4AGNX@80864|Comamonadaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_1003666_7 937777.Deipe_0861 1.478e-149 481.0 COG0473@1|root,COG0473@2|Bacteria,1WKWN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus CE PFAM Isocitrate isopropylmalate dehydrogenase - - 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - - Iso_dh DYD2_k127_1003666_4 1123368.AUIS01000001_gene2023 8.456e-181 583.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,2NCS6@225057|Acidithiobacillales 225057|Acidithiobacillales E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD2_k127_1003666_6 1163617.SCD_n01821 1.627e-163 518.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria 28216|Betaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA DYD2_k127_1003666_10 1266925.JHVX01000009_gene40 1.396e-120 403.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,3728I@32003|Nitrosomonadales 28216|Betaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C DYD2_k127_1003666_30 1095769.CAHF01000011_gene2402 2.558e-67 231.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,4741A@75682|Oxalobacteraceae 28216|Betaproteobacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK DYD2_k127_1003666_5 323848.Nmul_A2379 2.663e-164 524.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,371VW@32003|Nitrosomonadales 28216|Betaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM DYD2_k127_1003666_31 1163617.SCD_n01811 4.629e-67 239.0 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria 28216|Betaproteobacteria NU Type IV pilus biogenesis stability protein PilW pilF - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_16,TPR_17,TPR_19,TPR_2,TPR_8 DYD2_k127_1003666_40 1163617.SCD_n01810 7.929e-40 162.0 COG1426@1|root,COG4787@1|root,COG1426@2|Bacteria,COG4787@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria 28216|Betaproteobacteria N Transcriptional regulator - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 DYD2_k127_1003666_2 713586.KB900536_gene284 1.057e-188 603.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1WW8H@135613|Chromatiales 135613|Chromatiales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE DYD2_k127_1003666_3 1288494.EBAPG3_26420 1.254e-187 597.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,371PK@32003|Nitrosomonadales 28216|Betaproteobacteria J synthetase, class II (G H P hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD2_k127_106516_7 228410.NE1172 1.768e-72 252.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,372NX@32003|Nitrosomonadales 28216|Betaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 DYD2_k127_106516_8 580332.Slit_2800 2.128e-53 198.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding DYD2_k127_106516_3 1288494.EBAPG3_7520 3.282e-121 399.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,371XY@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT DYD2_k127_106516_1 1101195.Meth11DRAFT_1320 1.919e-220 698.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,2KKUB@206350|Nitrosomonadales 206350|Nitrosomonadales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C DYD2_k127_106516_5 331869.BAL199_18128 1.875e-96 323.0 COG3836@1|root,COG3836@2|Bacteria,1RCR7@1224|Proteobacteria,2U59U@28211|Alphaproteobacteria 28211|Alphaproteobacteria G HpcH/HpaI aldolase/citrate lyase family - - - - - - - - - - - - HpcH_HpaI DYD2_k127_106516_0 1454004.AW11_03339 2.826e-258 804.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,1KQ68@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM DYD2_k127_106516_6 1095769.CAHF01000001_gene3462 1.26e-90 301.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,47348@75682|Oxalobacteraceae 28216|Betaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB DYD2_k127_106516_2 1454004.AW11_03340 4.301e-152 483.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,1KQK5@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB DYD2_k127_106516_4 1304883.KI912532_gene2757 3.942e-104 343.0 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VMMI@28216|Betaproteobacteria,2KW7J@206389|Rhodocyclales 206389|Rhodocyclales S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 DYD2_k127_106516_9 640081.Dsui_3393 4.583e-38 148.0 COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,2VKV2@28216|Betaproteobacteria,2KWJB@206389|Rhodocyclales 206389|Rhodocyclales P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger DYD2_k127_1066684_11 580332.Slit_1442 7.947e-122 393.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,44VFW@713636|Nitrosomonadales 28216|Betaproteobacteria E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 DYD2_k127_1066684_6 159087.Daro_1725 5.866e-146 472.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,2KVCM@206389|Rhodocyclales 206389|Rhodocyclales NU twitching motility protein - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD2_k127_1066684_15 522306.CAP2UW1_3639 1.677e-81 283.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,1KPYE@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria J Belongs to the protein N5-glutamine methyltransferase family prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS DYD2_k127_1066684_13 1163617.SCD_n01482 5.16e-90 306.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria 28216|Betaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD2_k127_1066684_12 1288494.EBAPG3_16010 1.933e-97 327.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,372G5@32003|Nitrosomonadales 28216|Betaproteobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 DYD2_k127_1066684_16 265072.Mfla_1573 1.374e-44 164.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,2KP76@206350|Nitrosomonadales 206350|Nitrosomonadales L Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd DYD2_k127_1066684_4 1163617.SCD_n01510 1.784e-187 599.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 DYD2_k127_1066684_17 1123392.AQWL01000004_gene2785 8.43e-38 151.0 COG3637@1|root,COG3637@2|Bacteria,1PWS4@1224|Proteobacteria,2WAG8@28216|Betaproteobacteria,1KTGR@119069|Hydrogenophilales 119069|Hydrogenophilales M Lipid A 3-O-deacylase (PagL) - - - - - - - - - - - - PagL DYD2_k127_1066684_1 296591.Bpro_3358 0.0 1230.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,4AARI@80864|Comamonadaceae 28216|Betaproteobacteria H Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD2_k127_1066684_14 1380394.JADL01000001_gene2346 4.262e-89 301.0 COG1028@1|root,COG1028@2|Bacteria,1QWBB@1224|Proteobacteria,2U2FD@28211|Alphaproteobacteria,2JVVT@204441|Rhodospirillales 204441|Rhodospirillales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 DYD2_k127_1066684_10 1110502.TMO_1956 4.814e-123 406.0 COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria,2TUBJ@28211|Alphaproteobacteria,2JPTM@204441|Rhodospirillales 204441|Rhodospirillales G COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_1066684_9 395494.Galf_1339 8.862e-124 408.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,44WDD@713636|Nitrosomonadales 28216|Betaproteobacteria C PFAM Alcohol dehydrogenase GroES domain protein - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD2_k127_1066684_8 391038.Bphy_1718 3.608e-127 418.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2VHQX@28216|Betaproteobacteria,1K0KZ@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM AFG1-family ATPase yhcM - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase DYD2_k127_1066684_2 864073.HFRIS_010459 5.832e-227 712.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,4734P@75682|Oxalobacteraceae 28216|Betaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain odhL GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim DYD2_k127_1066684_5 557598.LHK_02415 3.572e-166 538.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,2KPJ7@206351|Neisseriales 206351|Neisseriales C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD2_k127_1066684_0 1288494.EBAPG3_15680 0.0 1281.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,371W3@32003|Nitrosomonadales 28216|Betaproteobacteria C dehydrogenase, E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr DYD2_k127_1066684_3 1144342.PMI40_01823 1.514e-210 661.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,472V7@75682|Oxalobacteraceae 28216|Betaproteobacteria H Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD2_k127_1066684_18 1123073.KB899244_gene428 3.112e-18 91.0 COG2938@1|root,COG2938@2|Bacteria 2|Bacteria C An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH sdhE GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 1.3.5.1,1.3.5.4 ko:K00240,ko:K09159 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000,ko02048 - - - Sdh5 DYD2_k127_1066684_7 1288494.EBAPG3_15710 1.388e-134 430.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,372KC@32003|Nitrosomonadales 28216|Betaproteobacteria C succinate dehydrogenase fumarate reductase sdhB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17,Fer4_8 DYD2_k127_1127738_2 1090318.ATTI01000001_gene1159 7.411e-266 828.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,2K00X@204457|Sphingomonadales 204457|Sphingomonadales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD2_k127_1127738_22 395493.BegalDRAFT_1189 4.183e-30 126.0 2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,1SH3A@1236|Gammaproteobacteria,463C1@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - DYD2_k127_1127738_9 1123368.AUIS01000015_gene2640 4.213e-123 405.0 COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,2NC8V@225057|Acidithiobacillales 225057|Acidithiobacillales S Lipocalin-like domain - - - - - - - - - - - - CrtC,Lipocalin_9 DYD2_k127_1127738_3 381666.H16_B1609 2.301e-248 792.0 COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,2VJAI@28216|Betaproteobacteria,1K2BP@119060|Burkholderiaceae 28216|Betaproteobacteria MV FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_1127738_15 1288494.EBAPG3_20560 1.61e-77 267.0 COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,2VIQD@28216|Betaproteobacteria,371Q9@32003|Nitrosomonadales 28216|Betaproteobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_1127738_13 1268622.AVS7_03045 4.226e-79 288.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4ABD6@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_1127738_6 402626.Rpic_1128 1.277e-193 617.0 COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,2VH3U@28216|Betaproteobacteria,1K1TG@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM Rhodanese domain protein - - - - - - - - - - - - Rhodanese DYD2_k127_1127738_8 1288494.EBAPG3_26980 5.275e-162 523.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,371QX@32003|Nitrosomonadales 28216|Betaproteobacteria JKL Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C DYD2_k127_1127738_14 1123487.KB892836_gene3269 1.079e-77 272.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2VKQH@28216|Betaproteobacteria,2KW5S@206389|Rhodocyclales 206389|Rhodocyclales L HNH endonuclease - - - - - - - - - - - - HNH_5 DYD2_k127_1127738_21 1101195.Meth11DRAFT_2522 6.661e-54 199.0 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2VSC6@28216|Betaproteobacteria,2KMZR@206350|Nitrosomonadales 206350|Nitrosomonadales S Protein of unknown function (DUF1223) - - - - - - - - - - - - DUF1223 DYD2_k127_1127738_11 1288494.EBAPG3_1800 5.992e-87 295.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,3729G@32003|Nitrosomonadales 28216|Betaproteobacteria J Belongs to the SUA5 family yciO - - - - - - - - - - - Sua5_yciO_yrdC DYD2_k127_1127738_4 1163617.SCD_n01478 2.511e-221 691.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria 28216|Betaproteobacteria J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b DYD2_k127_1127738_10 887062.HGR_12057 4.711e-94 321.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,4AB2X@80864|Comamonadaceae 28216|Betaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA DYD2_k127_1127738_16 1288494.EBAPG3_1840 8.414e-74 254.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,372XP@32003|Nitrosomonadales 28216|Betaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB DYD2_k127_1127738_7 1454004.AW11_00495 2.002e-168 537.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria 28216|Betaproteobacteria G Glucose sorbosone yliI - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH DYD2_k127_1127738_23 582744.Msip34_1538 8.642e-18 88.0 2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,2VY3B@28216|Betaproteobacteria,2KNXC@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - DYD2_k127_1127738_20 1163617.SCD_n01885 3.111e-57 205.0 COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,2VTR8@28216|Betaproteobacteria 28216|Betaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 DYD2_k127_1127738_12 713587.THITH_01405 2.945e-85 289.0 2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,1RRV2@1236|Gammaproteobacteria,1WXVA@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD2_k127_1127738_18 1096769.Pelub83DRAFT_0318 4.282e-67 231.0 COG1146@1|root,COG1146@2|Bacteria,1R4GP@1224|Proteobacteria 1224|Proteobacteria C reductase, beta subunit aprB - 1.8.99.2 ko:K00395 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - APS-reductase_C,Fer4,Fer4_9 DYD2_k127_1127738_1 859653.HIMB5_00004980 0.0 1046.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2TSN4@28211|Alphaproteobacteria 28211|Alphaproteobacteria C succinate dehydrogenase fumarate reductase, flavoprotein subunit MA20_14860 - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD2_k127_1127738_5 713586.KB900536_gene2525 4.341e-212 665.0 COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales 135613|Chromatiales P Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 DYD2_k127_1127738_19 1123368.AUIS01000028_gene1310 3.101e-66 246.0 COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,1S4SH@1236|Gammaproteobacteria,2NCF7@225057|Acidithiobacillales 225057|Acidithiobacillales MU CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - - - - - - - - - - OEP DYD2_k127_1127738_17 1123257.AUFV01000007_gene116 8.274e-72 259.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,1RQ67@1236|Gammaproteobacteria,1XA98@135614|Xanthomonadales 135614|Xanthomonadales M Biotin-lipoyl like - - - ko:K07799 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_D23 DYD2_k127_1127738_0 1123392.AQWL01000005_gene3047 0.0 1185.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSAB@119069|Hydrogenophilales 119069|Hydrogenophilales V Patched family - - - - - - - - - - - - ACR_tran DYD2_k127_1127738_24 1444309.JAQG01000131_gene3969 6.23e-07 55.0 2EHF3@1|root,33B70@2|Bacteria,1VP4D@1239|Firmicutes,4HZXQ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - DYD2_k127_1167706_4 1167006.UWK_03275 6.988e-30 136.0 COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MGJ@68525|delta/epsilon subdivisions,2WJ5E@28221|Deltaproteobacteria,2MHXN@213118|Desulfobacterales 28221|Deltaproteobacteria S TIGRFAM TRAP transporter solute receptor, TAXI family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD2_k127_1167706_1 414684.RC1_1846 4.563e-78 270.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,2JQYQ@204441|Rhodospirillales 204441|Rhodospirillales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 DYD2_k127_1167706_0 1123072.AUDH01000012_gene3499 7.418e-122 401.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VFXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_1167706_2 1123319.AUBE01000008_gene3889 2.394e-45 177.0 COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria 201174|Actinobacteria I 3-hydroxyisobutyrate dehydrogenase garR - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD2_k127_1167706_3 640081.Dsui_2224 2.585e-36 142.0 COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VW5P@28216|Betaproteobacteria,2KXN3@206389|Rhodocyclales 206389|Rhodocyclales S protein conserved in bacteria - - - ko:K09790 - - - - ko00000 - - - DUF454 DYD2_k127_1208586_12 404589.Anae109_1967 1.316e-07 53.0 COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria 1224|Proteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD2_k127_1208586_9 864051.BurJ1DRAFT_1863 1.351e-27 112.0 COG1724@1|root,COG1724@2|Bacteria 2|Bacteria N mRNA binding - - - ko:K07339 - - - - ko00000,ko01000,ko02048 - - - HicA_toxin DYD2_k127_1208586_8 187272.Mlg_2272 6.725e-28 114.0 COG1598@1|root,COG1598@2|Bacteria,1NBIX@1224|Proteobacteria,1SCV3@1236|Gammaproteobacteria,1WZ6M@135613|Chromatiales 135613|Chromatiales S HicB_like antitoxin of bacterial toxin-antitoxin system - - - - - - - - - - - - HicB_lk_antitox DYD2_k127_1208586_5 1382304.JNIL01000001_gene2102 1.836e-91 309.0 COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,4HCWD@91061|Bacilli 91061|Bacilli S Belongs to the D-glutamate cyclase family ycsI - - - - - - - - - - - DUF1445 DYD2_k127_1208586_3 1037409.BJ6T_23800 5.71e-140 446.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR,SCP2 DYD2_k127_1208586_0 1037409.BJ6T_23810 3.318e-283 876.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 DYD2_k127_1208586_13 587753.EY04_02285 7.789e-06 49.0 2EGJB@1|root,33ABH@2|Bacteria,1NI1G@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_1208586_7 1123276.KB893262_gene4077 3.443e-34 136.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_23,Methyltransf_25,Methyltransf_31 DYD2_k127_1208586_4 1146883.BLASA_1457 2.252e-108 366.0 COG0654@1|root,COG0654@2|Bacteria,2GNA8@201174|Actinobacteria,4EUAG@85013|Frankiales 201174|Actinobacteria C FAD binding domain - - 1.14.13.10 ko:K19189 ko00760,ko01120,map00760,map01120 - R04130 RC00046 ko00000,ko00001,ko01000 - - - FAD_binding_3,NAD_binding_8 DYD2_k127_1208586_10 1321784.HMPREF1987_01940 5.049e-27 115.0 COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,25TW8@186804|Peptostreptococcaceae 186801|Clostridia S Thioesterase superfamily - - 3.1.2.29 ko:K18700 - - - - ko00000,ko01000 - - - 4HBT DYD2_k127_1208586_11 671143.DAMO_0166 1.208e-22 103.0 2EIBB@1|root,33C2R@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_1208586_2 1429916.X566_03490 1.686e-140 456.0 COG1454@1|root,COG1454@2|Bacteria,1RC9B@1224|Proteobacteria,2U6JQ@28211|Alphaproteobacteria,3K3TU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH DYD2_k127_1208586_1 631454.N177_1479 4.342e-168 544.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TQYI@28211|Alphaproteobacteria 28211|Alphaproteobacteria C CoA binding domain MA20_15065 - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD2_k127_1208586_6 639283.Snov_0368 2.402e-48 175.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,3F0K6@335928|Xanthobacteraceae 28211|Alphaproteobacteria CK CoA-binding domain protein - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig DYD2_k127_1232670_1 522306.CAP2UW1_2826 0.0 1072.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KQAC@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C SNARE associated Golgi protein merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc DYD2_k127_1232670_8 864051.BurJ1DRAFT_3479 4.213e-94 316.0 COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,2VP38@28216|Betaproteobacteria,1KN8D@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 DYD2_k127_1232670_9 1411123.JQNH01000001_gene1175 3.038e-86 292.0 COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2TXAA@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferase group 2 family protein - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD2_k127_1232670_11 713586.KB900536_gene620 5.052e-51 188.0 COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,1S971@1236|Gammaproteobacteria,1WYN8@135613|Chromatiales 135613|Chromatiales S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 DYD2_k127_1232670_14 1288494.EBAPG3_8750 5.338e-38 145.0 2E0X2@1|root,32WE0@2|Bacteria,1R38G@1224|Proteobacteria,2VV4E@28216|Betaproteobacteria,373CI@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of Unknown function (DUF2784) - - - - - - - - - - - - DUF2784 DYD2_k127_1232670_4 1304883.KI912532_gene1300 5.522e-165 531.0 COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,2KVMP@206389|Rhodocyclales 206389|Rhodocyclales S sulfide dehydrogenase soxF - 1.8.2.1 ko:K05301 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00528 RC00168 ko00000,ko00001,ko01000 - - - FCSD-flav_bind,Pyr_redox_2,TAT_signal DYD2_k127_1232670_16 1000565.METUNv1_02965 1.06e-27 117.0 COG2863@1|root,COG2863@2|Bacteria,1NGJ1@1224|Proteobacteria,2VVR2@28216|Betaproteobacteria,2KX1J@206389|Rhodocyclales 206389|Rhodocyclales C Cytochrome c, class I - - - - - - - - - - - - Cytochrom_C DYD2_k127_1232670_0 583345.Mmol_1941 0.0 1203.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KKYH@206350|Nitrosomonadales 206350|Nitrosomonadales O TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA - - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD2_k127_1232670_12 323848.Nmul_A2247 5.58e-45 165.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,373HT@32003|Nitrosomonadales 28216|Betaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS DYD2_k127_1232670_15 882378.RBRH_00943 2.018e-35 136.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1K9CX@119060|Burkholderiaceae 28216|Betaproteobacteria K Cold shock protein cspD - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD2_k127_1232670_2 1521187.JPIM01000015_gene3766 1.851e-258 806.0 COG2225@1|root,COG2225@2|Bacteria,2G63R@200795|Chloroflexi,374XP@32061|Chloroflexia 32061|Chloroflexia H TIGRFAM malate synthase A - - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase DYD2_k127_1232670_3 323848.Nmul_A2243 3.951e-182 576.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,371SF@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans DYD2_k127_1232670_10 1500897.JQNA01000002_gene4715 1.588e-51 190.0 COG0695@1|root,COG0695@2|Bacteria,1RC6T@1224|Proteobacteria,2VQW9@28216|Betaproteobacteria,1K5H4@119060|Burkholderiaceae 28216|Betaproteobacteria O DinB superfamily - - - - - - - - - - - - DinB_2,Glutaredoxin DYD2_k127_1232670_17 1463858.JOHR01000004_gene1526 2.006e-14 78.0 COG1765@1|root,COG1765@2|Bacteria,2GQ5Y@201174|Actinobacteria 201174|Actinobacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD2_k127_1232670_6 762376.AXYL_03475 6.152e-99 334.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_1232670_5 1123504.JQKD01000019_gene5540 3.661e-157 509.0 COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2VHXE@28216|Betaproteobacteria,4ABHK@80864|Comamonadaceae 28216|Betaproteobacteria E Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA DYD2_k127_1232670_7 412597.AEPN01000001_gene3058 3.467e-98 327.0 COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,2TUFY@28211|Alphaproteobacteria,2PVHK@265|Paracoccus 28211|Alphaproteobacteria J Elongation factor SelB, winged helix - - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 DYD2_k127_1249255_7 1131814.JAFO01000001_gene1056 4.625e-70 243.0 COG0687@1|root,COG0687@2|Bacteria,1NE7Q@1224|Proteobacteria,2U3SS@28211|Alphaproteobacteria,3F26C@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6,SBP_bac_8 DYD2_k127_1249255_5 1131814.JAFO01000001_gene1055 3.178e-98 329.0 COG1176@1|root,COG1176@2|Bacteria,1R44Q@1224|Proteobacteria,2U2M2@28211|Alphaproteobacteria,3F13B@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Binding-protein-dependent transport system inner membrane component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 DYD2_k127_1249255_6 426355.Mrad2831_1250 1.715e-90 305.0 COG1177@1|root,COG1177@2|Bacteria,1R506@1224|Proteobacteria,2U37T@28211|Alphaproteobacteria,1JZ6U@119045|Methylobacteriaceae 28211|Alphaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 DYD2_k127_1249255_10 1235457.C404_01090 7.299e-35 136.0 COG2351@1|root,COG2351@2|Bacteria,1RFPP@1224|Proteobacteria,2W792@28216|Betaproteobacteria,1KE3W@119060|Burkholderiaceae 28216|Betaproteobacteria S HIUase/Transthyretin family - - - - - - - - - - - - Transthyretin DYD2_k127_1249255_12 911045.PSE_0722 0.0006339 46.0 COG1765@1|root,COG1765@2|Bacteria,1N0BA@1224|Proteobacteria,2UIZU@28211|Alphaproteobacteria 28211|Alphaproteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD2_k127_1249255_11 595460.RRSWK_06191 6.378e-09 60.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD2_k127_1249255_8 864051.BurJ1DRAFT_3377 1.778e-68 248.0 COG1802@1|root,COG1802@2|Bacteria,1MW9G@1224|Proteobacteria,2VQ9U@28216|Betaproteobacteria,1KKKQ@119065|unclassified Burkholderiales 28216|Betaproteobacteria K GntR family - - - - - - - - - - - - FCD,GntR DYD2_k127_1249255_2 1149133.ppKF707_1819 1.253e-175 584.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RR5Z@1236|Gammaproteobacteria,1YDPU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Amidase atzF - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase DYD2_k127_1249255_1 1123060.JONP01000009_gene2139 2.433e-225 726.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2JR8I@204441|Rhodospirillales 204441|Rhodospirillales P Oligopeptide/dipeptide transporter, C-terminal region - - - - - - - - - - - - ABC_tran,oligo_HPY DYD2_k127_1249255_4 1504981.KO116_0964 1.392e-133 431.0 COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,1RMMR@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Binding-protein-dependent transport systems inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N DYD2_k127_1249255_3 1121033.AUCF01000012_gene937 6.32e-144 463.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,2JQKC@204441|Rhodospirillales 204441|Rhodospirillales EP Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 DYD2_k127_1249255_0 1121033.AUCF01000012_gene936 1.145e-252 792.0 COG0747@1|root,COG0747@2|Bacteria,1MWR7@1224|Proteobacteria,2TS51@28211|Alphaproteobacteria,2JR2K@204441|Rhodospirillales 204441|Rhodospirillales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD2_k127_1249255_9 1125973.JNLC01000012_gene999 6.22e-49 180.0 COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,2U607@28211|Alphaproteobacteria,3JZMZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Serine hydrolase - - - ko:K07002 - - - - ko00000 - - - Ser_hydrolase DYD2_k127_1280515_33 1163617.SCD_n02939 1.797e-47 178.0 COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,2VRKW@28216|Betaproteobacteria 28216|Betaproteobacteria S mRNA catabolic process - - - - - - - - - - - - - DYD2_k127_1280515_13 580332.Slit_0037 6.316e-158 503.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,44VC7@713636|Nitrosomonadales 28216|Betaproteobacteria H Delta-aminolevulinic acid dehydratase hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD DYD2_k127_1280515_31 1163617.SCD_n02936 1.042e-58 214.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria 28216|Betaproteobacteria D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 DYD2_k127_1280515_28 93220.LV28_12770 6.362e-67 235.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,1K1BD@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM cytochrome c, class I cyc - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD2_k127_1280515_6 1163617.SCD_n02929 1.336e-200 635.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria 28216|Betaproteobacteria H Aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_1280515_30 1266925.JHVX01000015_gene215 2.769e-63 225.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,3734Y@32003|Nitrosomonadales 28216|Betaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI DYD2_k127_1280515_17 1163617.SCD_n02927 1.05e-137 442.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria 28216|Betaproteobacteria H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin DYD2_k127_1280515_37 1000565.METUNv1_03302 9.365e-30 118.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,2KXDH@206389|Rhodocyclales 206389|Rhodocyclales C Rubredoxin - - - - - - - - - - - - Rubredoxin DYD2_k127_1280515_29 323848.Nmul_A2625 4.184e-65 225.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,3736C@32003|Nitrosomonadales 28216|Betaproteobacteria E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione gloA - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD2_k127_1280515_26 261292.Nit79A3_2012 4.576e-96 320.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,371YX@32003|Nitrosomonadales 28216|Betaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD DYD2_k127_1280515_19 265072.Mfla_2151 1.496e-126 414.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,2KKW8@206350|Nitrosomonadales 206350|Nitrosomonadales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA DYD2_k127_1280515_12 1163617.SCD_n02560 2.247e-158 511.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria 28216|Betaproteobacteria M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3,SurA_N DYD2_k127_1280515_7 1163617.SCD_n02559 5.34e-198 642.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria 28216|Betaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C DYD2_k127_1280515_20 265072.Mfla_2148 7.403e-125 410.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,2KM5S@206350|Nitrosomonadales 206350|Nitrosomonadales S Phosphotransferase enzyme family - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH DYD2_k127_1280515_27 580332.Slit_0047 9.928e-78 267.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,44V8V@713636|Nitrosomonadales 28216|Betaproteobacteria M Nucleotidyl transferase rmlA - 2.7.7.99 ko:K00992 ko00520,ko01100,map00520,map01100 - R11025 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase DYD2_k127_1280515_39 396588.Tgr7_0561 1.323e-13 76.0 2CH9Q@1|root,344Q6@2|Bacteria,1P007@1224|Proteobacteria,1SS1R@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_1280515_10 1266925.JHVX01000008_gene274 2.981e-190 603.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,372V1@32003|Nitrosomonadales 28216|Betaproteobacteria E peptidase M24B, X-Pro dipeptidase aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 DYD2_k127_1280515_25 1123393.KB891316_gene1656 4.091e-98 333.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,1KSHU@119069|Hydrogenophilales 119069|Hydrogenophilales CH FAD binding domain - - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD2_k127_1280515_11 323848.Nmul_A0131 8.996e-169 537.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,371XV@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus DYD2_k127_1280515_38 1163617.SCD_n00039 1.074e-26 114.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria 28216|Betaproteobacteria KL Belongs to the transcriptional regulatory Fis family fis - - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 DYD2_k127_1280515_5 1454004.AW11_03197 3.988e-201 635.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,1KPPN@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family bioA - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_1280515_18 1163617.SCD_n00497 1.119e-135 451.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria 28216|Betaproteobacteria M D-alanyl-D-alanine carboxypeptidase dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 DYD2_k127_1280515_3 1485544.JQKP01000002_gene1585 2.424e-260 808.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,44VAJ@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis ubiD - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD2_k127_1280515_22 323848.Nmul_A2611 1.609e-106 355.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,3726Q@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD2_k127_1280515_34 1131553.JIBI01000027_gene2387 7.78e-43 162.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria,372XF@32003|Nitrosomonadales 28216|Betaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC - 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - - Chor_lyase DYD2_k127_1280515_0 1163617.SCD_n00508 2.7e-284 891.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria 28216|Betaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge DYD2_k127_1280515_32 765912.Thimo_0759 3.473e-48 176.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1WY7E@135613|Chromatiales 135613|Chromatiales J PFAM Endoribonuclease L-PSP - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP DYD2_k127_1280515_14 296591.Bpro_5277 5.626e-153 496.0 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2VK7F@28216|Betaproteobacteria,4AJ1Q@80864|Comamonadaceae 28216|Betaproteobacteria C Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_1280515_24 596154.Alide2_1835 2.927e-101 342.0 COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2VH8G@28216|Betaproteobacteria,4AB42@80864|Comamonadaceae 28216|Betaproteobacteria I Acyl-CoA dehydrogenase, N-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N DYD2_k127_1280515_35 1122604.JONR01000003_gene1358 9.322e-40 160.0 COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,1XCMR@135614|Xanthomonadales 135614|Xanthomonadales S SapC - - - - - - - - - - - - SapC DYD2_k127_1280515_36 1121106.JQKB01000003_gene2551 5.22e-39 160.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE PrpD family protein MA20_23745 - - - - - - - - - - - MmgE_PrpD DYD2_k127_1280515_21 1163617.SCD_n00028 2.253e-115 385.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria 28216|Betaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD2_k127_1280515_1 1415779.JOMH01000001_gene2583 1.355e-275 856.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1X4TP@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the IlvD Edd family - - - - - - - - - - - - ILVD_EDD DYD2_k127_1280515_2 1288494.EBAPG3_17760 1.796e-270 851.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria,372B1@32003|Nitrosomonadales 28216|Betaproteobacteria O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH DYD2_k127_1280515_16 580332.Slit_0281 8.009e-140 468.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VIMC@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase dctB - 2.7.13.3 ko:K10125 ko02020,map02020 M00504 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1 DYD2_k127_1280515_8 580332.Slit_0282 7.553e-192 618.0 COG0515@1|root,COG3437@1|root,COG0515@2|Bacteria,COG3437@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WA3@713636|Nitrosomonadales 28216|Betaproteobacteria T PFAM Serine threonine-protein kinase-like domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase DYD2_k127_1280515_15 228410.NE1876 1.228e-145 469.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,372SB@32003|Nitrosomonadales 28216|Betaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas DYD2_k127_1280515_23 1380394.JADL01000004_gene5909 4.57e-105 348.0 COG0346@1|root,COG0346@2|Bacteria,1MX75@1224|Proteobacteria,2TRQS@28211|Alphaproteobacteria,2JVNN@204441|Rhodospirillales 204441|Rhodospirillales E lactoylglutathione lyase activity - - - - - - - - - - - - - DYD2_k127_1280515_9 1163617.SCD_n00037 1.933e-190 609.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria 28216|Betaproteobacteria F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N DYD2_k127_1280515_4 1266925.JHVX01000008_gene269 2.246e-236 740.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,372QA@32003|Nitrosomonadales 28216|Betaproteobacteria F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS DYD2_k127_1340742_3 983917.RGE_12000 1.18e-83 286.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2WFS6@28216|Betaproteobacteria 28216|Betaproteobacteria S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC DYD2_k127_1340742_2 1267005.KB911263_gene1311 5.459e-118 383.0 COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2TTZV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 DYD2_k127_1340742_4 266117.Rxyl_0239 1.56e-67 235.0 COG0625@1|root,COG0625@2|Bacteria 2|Bacteria O glutathione transferase activity - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N,GST_N_3 DYD2_k127_1340742_5 667632.KB890165_gene2332 1.723e-48 178.0 COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2VREK@28216|Betaproteobacteria,1KH81@119060|Burkholderiaceae 28216|Betaproteobacteria S carbon monoxide dehydrogenase coxG - - ko:K09386 - - - - ko00000 - - - COXG DYD2_k127_1340742_1 1226994.AMZB01000134_gene4645 1.043e-130 431.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Malonyl-CoA decarboxylase - - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N DYD2_k127_1340742_0 1218074.BAXZ01000002_gene331 1.122e-135 438.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,1K1XI@119060|Burkholderiaceae 28216|Betaproteobacteria O XdhC and CoxI family coxI - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI DYD2_k127_1451062_1 930166.CD58_17470 1.858e-197 635.0 COG1538@1|root,COG1538@2|Bacteria,1MUHM@1224|Proteobacteria,1RNNS@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU outer membrane efflux protein - - - - - - - - - - - - OEP DYD2_k127_1451062_14 930166.CD58_17475 3.432e-67 237.0 COG0845@1|root,COG0845@2|Bacteria,1R99C@1224|Proteobacteria,1RZS0@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 DYD2_k127_1451062_3 365046.Rta_22810 1.093e-132 443.0 COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2VIES@28216|Betaproteobacteria,4AHNX@80864|Comamonadaceae 28216|Betaproteobacteria M Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 DYD2_k127_1451062_0 930166.CD58_17485 9.193e-210 677.0 COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,1RRTY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Peptidase M50 - - - ko:K16922 - - - - ko00000,ko01002 - - - Biotin_lipoyl_2,HlyD_3 DYD2_k127_1451062_6 314278.NB231_11744 3.249e-123 408.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1RZ44@1236|Gammaproteobacteria 1236|Gammaproteobacteria N OmpA MotB - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA DYD2_k127_1451062_9 1207063.P24_11702 7.096e-101 344.0 COG1511@1|root,COG1511@2|Bacteria,1NYJB@1224|Proteobacteria,2TSX0@28211|Alphaproteobacteria,2JPFY@204441|Rhodospirillales 204441|Rhodospirillales S MotA TolQ ExbB proton channel family - - - - - - - - - - - - - DYD2_k127_1451062_2 1230476.C207_00196 3.116e-170 540.0 COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,2TVM0@28211|Alphaproteobacteria,3JW6H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase ligJ - 4.1.1.45,4.2.1.83 ko:K03392,ko:K10220 ko00362,ko00380,ko01100,ko01120,map00362,map00380,map01100,map01120 M00038 R04323,R04478 RC00498,RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD2_k127_1451062_22 1211114.ALIP01000124_gene743 1.125e-30 126.0 COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,1SFMR@1236|Gammaproteobacteria,1X7TA@135614|Xanthomonadales 135614|Xanthomonadales T Universal stress protein - - - - - - - - - - - - Usp DYD2_k127_1451062_4 330214.NIDE3598 9.972e-125 407.0 COG0702@1|root,COG0702@2|Bacteria 2|Bacteria GM epimerase - - - - - - - - - - - - NmrA DYD2_k127_1451062_12 1121946.AUAX01000016_gene4671 1.41e-94 321.0 COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4DBPI@85008|Micromonosporales 201174|Actinobacteria C Aldo/keto reductase family - - 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 - R01708 RC00116 ko00000,ko00001,ko01000 - - - Aldo_ket_red DYD2_k127_1451062_20 338969.Rfer_0637 6.127e-44 164.0 COG2905@1|root,COG2905@2|Bacteria,1N7MU@1224|Proteobacteria,2VVGU@28216|Betaproteobacteria 28216|Betaproteobacteria T Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD2_k127_1451062_21 1123060.JONP01000001_gene1180 1.339e-43 170.0 COG0725@1|root,COG0725@2|Bacteria,1PTVK@1224|Proteobacteria,2TU4Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - 5.3.3.7 ko:K22003 ko00660,map00660 - R02244 RC00668 ko00000,ko00001,ko01000 - - - SBP_bac_11 DYD2_k127_1451062_11 762376.AXYL_05754 3.34e-95 321.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VNWD@28216|Betaproteobacteria,3T5QG@506|Alcaligenaceae 28216|Betaproteobacteria G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II DYD2_k127_1451062_10 1437824.BN940_09286 1.132e-97 329.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VMVX@28216|Betaproteobacteria,3T72F@506|Alcaligenaceae 28216|Betaproteobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_1451062_5 1380394.JADL01000013_gene682 1.183e-123 404.0 COG2175@1|root,COG2175@2|Bacteria,1R5TE@1224|Proteobacteria,2U2FJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Taurine catabolism dioxygenase TauD, TfdA family - - - ko:K06912 ko00361,ko01120,ko01220,map00361,map01120,map01220 - R05419,R05493 RC01371,RC01372 ko00000,ko00001,ko01000 - - - TauD DYD2_k127_1451062_24 938709.AUSH02000001_gene1592 5.728e-12 76.0 2ATWF@1|root,31JFP@2|Bacteria,4NT3Q@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1451062_16 1380394.JADL01000001_gene2482 1.79e-53 205.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE PrpD family protein - - - - - - - - - - - - MmgE_PrpD DYD2_k127_1451062_18 1452718.JBOY01000020_gene687 1.59e-45 178.0 COG2199@1|root,COG3706@2|Bacteria,1R7V7@1224|Proteobacteria,1RYGS@1236|Gammaproteobacteria 1236|Gammaproteobacteria T (GGDEF) domain - - - - - - - - - - - - GGDEF DYD2_k127_1451062_17 1380394.JADL01000001_gene3025 4.486e-49 192.0 COG2021@1|root,COG2021@2|Bacteria,1QVBR@1224|Proteobacteria,2TWEP@28211|Alphaproteobacteria,2JZ5P@204441|Rhodospirillales 204441|Rhodospirillales E Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_1451062_13 381666.H16_B1793 1.4e-75 276.0 COG3181@1|root,COG3181@2|Bacteria,1N4MC@1224|Proteobacteria,2VKJS@28216|Betaproteobacteria,1KCQ9@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_1451062_8 748247.AZKH_2773 1.504e-109 364.0 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2VK8F@28216|Betaproteobacteria,2KWZJ@206389|Rhodocyclales 206389|Rhodocyclales O C-terminal domain of 1-Cys peroxiredoxin - - - - - - - - - - - - 1-cysPrx_C,AhpC-TSA DYD2_k127_1451062_23 333138.LQ50_20190 7.245e-29 126.0 COG0235@1|root,COG0235@2|Bacteria 2|Bacteria G Class ii aldolase araD - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II,UPF0066 DYD2_k127_1451062_19 1000565.METUNv1_03440 4.029e-45 171.0 COG1670@1|root,COG1670@2|Bacteria,1PZTX@1224|Proteobacteria,2W4BT@28216|Betaproteobacteria 28216|Betaproteobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 DYD2_k127_1451062_7 697282.Mettu_2130 9.359e-112 366.0 COG3217@1|root,COG3217@2|Bacteria,1QTF1@1224|Proteobacteria,1SVMA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MOSC domain - - - - - - - - - - - - MOSC DYD2_k127_1451062_25 566466.NOR53_834 1.907e-11 73.0 COG0790@1|root,COG0790@2|Bacteria,1PDUX@1224|Proteobacteria,1RW86@1236|Gammaproteobacteria,1JBN1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sel1-like repeats. - - - - - - - - - - - - Sel1 DYD2_k127_1451062_15 1380394.JADL01000001_gene3066 3.593e-66 231.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,2JQZD@204441|Rhodospirillales 204441|Rhodospirillales EH Thiamine pyrophosphate enzyme, central domain - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_1486085_5 1214065.BAGV01000062_gene994 6.841e-05 50.0 2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_1486085_4 748280.NH8B_1245 1.844e-20 94.0 29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,2VT0U@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - DUF1269 DYD2_k127_1486085_3 1123392.AQWL01000002_gene1852 1.624e-29 122.0 29GYT@1|root,303WG@2|Bacteria,1RET9@1224|Proteobacteria,2VT0U@28216|Betaproteobacteria,1KSBF@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - DYD2_k127_1486085_0 265072.Mfla_2280 2.213e-158 506.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,2KKH8@206350|Nitrosomonadales 206350|Nitrosomonadales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 DYD2_k127_1486085_1 1163617.SCD_n02499 1.924e-98 329.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase DYD2_k127_1486085_2 1163617.SCD_n02500 6.172e-73 262.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,2VSUT@28216|Betaproteobacteria 28216|Betaproteobacteria M LppC putative lipoprotein - - - ko:K07121 - - - - ko00000 - - - LppC DYD2_k127_1515599_2 1177179.A11A3_14602 1.318e-08 65.0 2EGR5@1|root,33AHA@2|Bacteria,1NH3C@1224|Proteobacteria,1SIE7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_1515599_0 596153.Alide_2607 1.397e-168 540.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,4AB40@80864|Comamonadaceae 28216|Betaproteobacteria S DinB superfamily egtB - - - - - - - - - - - DinB_2,FGE-sulfatase DYD2_k127_1598877_2 1123393.KB891317_gene2450 2.049e-167 536.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,1KSCK@119069|Hydrogenophilales 119069|Hydrogenophilales EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_1598877_3 472759.Nhal_2629 4.917e-158 506.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales 135613|Chromatiales E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD2_k127_1598877_0 580332.Slit_2068 0.0 1252.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,44VGS@713636|Nitrosomonadales 28216|Betaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD2_k127_1598877_5 76114.ebA913 1.371e-30 130.0 COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,2KW20@206389|Rhodocyclales 206389|Rhodocyclales M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA DYD2_k127_1598877_1 1288494.EBAPG3_24400 6.662e-181 577.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,37277@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 DYD2_k127_1598877_4 305700.B447_17983 5.443e-105 345.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,2KVHW@206389|Rhodocyclales 206389|Rhodocyclales H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_23 DYD2_k127_1601295_9 1097668.BYI23_A004770 9.714e-78 263.0 COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,2WEAK@28216|Betaproteobacteria,1K11E@119060|Burkholderiaceae 28216|Betaproteobacteria K response regulator qseB - - ko:K02483,ko:K07666 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD2_k127_1601295_4 522306.CAP2UW1_1182 1.602e-130 435.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,1KQR0@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain qseC - 2.7.13.3 ko:K02484,ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA DYD2_k127_1601295_1 748247.AZKH_3439 1.216e-166 537.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KVHE@206389|Rhodocyclales 206389|Rhodocyclales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD2_k127_1601295_16 748247.AZKH_4235 5.145e-23 100.0 2END2@1|root,33G0J@2|Bacteria,1NIFI@1224|Proteobacteria,2VVU7@28216|Betaproteobacteria,2KZCF@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD2_k127_1601295_11 1304883.KI912532_gene1924 1.219e-49 186.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2VREV@28216|Betaproteobacteria,2KWCT@206389|Rhodocyclales 206389|Rhodocyclales L NUDIX domain - - - - - - - - - - - - NUDIX DYD2_k127_1601295_3 1288494.EBAPG3_27890 9.46e-131 427.0 COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,3722R@32003|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin DYD2_k127_1601295_13 1122236.KB905141_gene1119 9.301e-44 167.0 COG0782@1|root,COG0782@2|Bacteria,1RHU5@1224|Proteobacteria,2W3NT@28216|Betaproteobacteria,2KMUI@206350|Nitrosomonadales 206350|Nitrosomonadales K PFAM transcription elongation factor GreA GreB - - - - - - - - - - - - GreA_GreB DYD2_k127_1601295_8 1288494.EBAPG3_23070 3.461e-80 278.0 COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,37295@32003|Nitrosomonadales 28216|Betaproteobacteria H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group cobD - 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - CobD_Cbib DYD2_k127_1601295_5 265072.Mfla_1475 3.286e-100 336.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,2KM0D@206350|Nitrosomonadales 206350|Nitrosomonadales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase DYD2_k127_1601295_12 1266925.JHVX01000003_gene417 1.146e-46 170.0 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,373A7@32003|Nitrosomonadales 28216|Betaproteobacteria H diol metabolic process - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a DYD2_k127_1601295_2 1131553.JIBI01000016_gene616 2.968e-154 497.0 COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,372MW@32003|Nitrosomonadales 28216|Betaproteobacteria O PFAM Peptidase M48 htpX_2 - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N DYD2_k127_1601295_7 243365.CV_2368 4.727e-84 282.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,2KPCE@206351|Neisseriales 206351|Neisseriales L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn - - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T DYD2_k127_1601295_14 765912.Thimo_3613 1.71e-34 139.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1WY72@135613|Chromatiales 135613|Chromatiales O TIGRFAM clan AA aspartic protease, TIGR02281 family - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas DYD2_k127_1601295_17 1121939.L861_17180 2.259e-18 86.0 2E7PS@1|root,3325B@2|Bacteria,1QNSP@1224|Proteobacteria,1SI7D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - DYD2_k127_1601295_0 261292.Nit79A3_3044 2.908e-185 597.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria,371Q3@32003|Nitrosomonadales 28216|Betaproteobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI DYD2_k127_1601295_15 62928.azo1155 1.59e-27 116.0 COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,2VTZY@28216|Betaproteobacteria,2KX00@206389|Rhodocyclales 206389|Rhodocyclales S effector of murein hydrolase LrgA - - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA DYD2_k127_1601295_6 159087.Daro_3106 1.971e-87 306.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2VH4N@28216|Betaproteobacteria,2KVYR@206389|Rhodocyclales 206389|Rhodocyclales M of murein hydrolase - - - - - - - - - - - - LrgB DYD2_k127_1601295_10 1163617.SCD_n02473 9.811e-53 194.0 COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria 28216|Betaproteobacteria E Etoposide-induced protein 2.4 (EI24) - - - - - - - - - - - - EI24 DYD2_k127_1603726_22 1129374.AJE_09117 0.000369 46.0 COG0515@1|root,COG0631@1|root,COG0515@2|Bacteria,COG0631@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,464NH@72275|Alteromonadaceae 1236|Gammaproteobacteria T Serine threonine protein - - 3.1.3.16 ko:K01090,ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2,Pkinase DYD2_k127_1603726_0 1123368.AUIS01000007_gene2765 5.334e-236 755.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1SMM0@1236|Gammaproteobacteria,2NBR8@225057|Acidithiobacillales 225057|Acidithiobacillales P von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - DYD2_k127_1603726_4 396588.Tgr7_2164 9.493e-131 422.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1WWX8@135613|Chromatiales 1236|Gammaproteobacteria S ATPase associated with various cellular activities, AAA_5 - - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C DYD2_k127_1603726_16 1123368.AUIS01000007_gene2767 2.754e-33 133.0 2CJFI@1|root,32XF5@2|Bacteria,1N623@1224|Proteobacteria,1SRCG@1236|Gammaproteobacteria,2NCZV@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - DYD2_k127_1603726_8 323848.Nmul_A2119 1.655e-97 321.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria,372KE@32003|Nitrosomonadales 28216|Betaproteobacteria S LemA family - - - ko:K03744 - - - - ko00000 - - - LemA DYD2_k127_1603726_9 1266925.JHVX01000006_gene2144 3.115e-93 312.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,37236@32003|Nitrosomonadales 28216|Betaproteobacteria L TIGRFAM Phage SPO1 DNA polymerase-related protein dpo - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD2_k127_1603726_14 292415.Tbd_1724 1.672e-40 157.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,1KRRR@119069|Hydrogenophilales 119069|Hydrogenophilales K Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 DYD2_k127_1603726_10 1163617.SCD_n01596 3.401e-79 270.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria 28216|Betaproteobacteria O Peptidase M22 glycoprotease yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 DYD2_k127_1603726_20 1236959.BAMT01000003_gene603 3.189e-08 61.0 2BUM0@1|root,32PXK@2|Bacteria,1PJJB@1224|Proteobacteria,2W814@28216|Betaproteobacteria,2KN9X@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - DYD2_k127_1603726_1 1207075.PputUW4_03009 8.67e-155 497.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 DYD2_k127_1603726_17 1207063.P24_06931 4.329e-33 134.0 COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2U9DU@28211|Alphaproteobacteria,2JTAM@204441|Rhodospirillales 204441|Rhodospirillales J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD2_k127_1603726_21 1304275.C41B8_06502 9.705e-08 64.0 2C99D@1|root,2Z7Y8@2|Bacteria,1R5JY@1224|Proteobacteria,1SI3Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DNA-sulfur modification-associated - - - - - - - - - - - - DndB DYD2_k127_1603726_3 1192124.LIG30_0335 9.717e-141 456.0 COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2VH8S@28216|Betaproteobacteria,1K2D3@119060|Burkholderiaceae 28216|Betaproteobacteria S Twin-arginine translocation pathway signal sequence - - - - - - - - - - - - DUF1501,TAT_signal DYD2_k127_1603726_2 267608.RSc1650 3.541e-148 485.0 COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2VIYI@28216|Betaproteobacteria,1KH1C@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 DYD2_k127_1603726_19 1031711.RSPO_c00381 5.908e-09 64.0 COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2VW0M@28216|Betaproteobacteria,1K77D@119060|Burkholderiaceae 28216|Betaproteobacteria DTZ EF-hand domain pair - - - - - - - - - - - - EF-hand_5 DYD2_k127_1603726_18 1163617.SCD_n01834 2.687e-22 106.0 2EIBB@1|root,32XEP@2|Bacteria,1MZDG@1224|Proteobacteria,2VUEA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_1603726_6 748247.AZKH_2736 1.053e-109 360.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,2KUNC@206389|Rhodocyclales 206389|Rhodocyclales K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ompR - - ko:K02483,ko:K07659 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD2_k127_1603726_5 640081.Dsui_2400 2.258e-121 404.0 COG0642@1|root,COG3850@1|root,COG0642@2|Bacteria,COG3850@2|Bacteria,1PA1G@1224|Proteobacteria,2WGUD@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase risS - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,RisS_PPD DYD2_k127_1603726_15 76114.ebA6539 7.717e-36 146.0 COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,2KWXS@206389|Rhodocyclales 206389|Rhodocyclales J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase DYD2_k127_1603726_12 323848.Nmul_A2126 8.381e-64 224.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,3731W@32003|Nitrosomonadales 28216|Betaproteobacteria F Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB DYD2_k127_1603726_11 1163617.SCD_n01757 6.279e-77 265.0 COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria 28216|Betaproteobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD - 2.7.7.60,4.6.1.12 ko:K00991,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD DYD2_k127_1603726_7 522306.CAP2UW1_2625 4.74e-102 338.0 COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria 28216|Betaproteobacteria S Belongs to the MEMO1 family - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo DYD2_k127_1603726_13 292415.Tbd_1586 3.747e-47 176.0 COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales 119069|Hydrogenophilales S Memo-like protein - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo DYD2_k127_1663923_6 1509405.GV67_12565 7.303e-143 464.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,4B8SA@82115|Rhizobiaceae 28211|Alphaproteobacteria C L-lactate dehydrogenase lldD2 - 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 - R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh DYD2_k127_1663923_0 56780.SYN_02218 7.821e-304 953.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD2_k127_1663923_17 338969.Rfer_3142 1.337e-67 236.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,4ABBS@80864|Comamonadaceae 28216|Betaproteobacteria S Belongs to the LOG family yvdD_1 - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD2_k127_1663923_5 1122134.KB893650_gene1358 1.752e-145 481.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1XICC@135619|Oceanospirillales 135619|Oceanospirillales S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 DYD2_k127_1663923_13 1163617.SCD_n00987 2.003e-76 260.0 COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria 28216|Betaproteobacteria S LemA Family - - - ko:K03744 - - - - ko00000 - - - LemA DYD2_k127_1663923_11 1163617.SCD_n00986 9.562e-83 284.0 2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,2VQ0G@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - GIDE DYD2_k127_1663923_2 62928.azo0376 5.145e-232 738.0 COG0010@1|root,COG4992@1|root,COG0010@2|Bacteria,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KWDX@206389|Rhodocyclales 206389|Rhodocyclales E COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family rocD - 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3,Arginase DYD2_k127_1663923_3 472759.Nhal_1431 4.147e-221 697.0 COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,1RY9G@1236|Gammaproteobacteria,1X2DF@135613|Chromatiales 135613|Chromatiales C Aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_1663923_10 1123354.AUDR01000014_gene1004 1.769e-97 326.0 COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2WGMM@28216|Betaproteobacteria 28216|Betaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 DYD2_k127_1663923_9 1000565.METUNv1_02982 2.939e-102 350.0 COG0515@1|root,COG2114@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,1PJRR@1224|Proteobacteria,2VHAU@28216|Betaproteobacteria,2KWHB@206389|Rhodocyclales 206389|Rhodocyclales KLT Protein kinase domain - - - - - - - - - - - - DUF4384,Pkinase DYD2_k127_1663923_8 1454004.AW11_01239 5.87e-114 374.0 COG2972@1|root,COG2972@2|Bacteria,1QYRK@1224|Proteobacteria,2WHJ2@28216|Betaproteobacteria 28216|Betaproteobacteria T Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365,HAMP DYD2_k127_1663923_22 314278.NB231_00345 3.378e-36 141.0 2D7FD@1|root,32TNY@2|Bacteria,1NAHU@1224|Proteobacteria,1S9DD@1236|Gammaproteobacteria,1WYZ8@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF1992) - - - - - - - - - - - - DUF1992 DYD2_k127_1663923_16 1205680.CAKO01000038_gene2040 5.9e-75 267.0 COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2U625@28211|Alphaproteobacteria 28211|Alphaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - DUF4189,PG_binding_1,Pkinase,WD40 DYD2_k127_1663923_12 1205680.CAKO01000038_gene2040 3.101e-82 291.0 COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2U625@28211|Alphaproteobacteria 28211|Alphaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - DUF4189,PG_binding_1,Pkinase,WD40 DYD2_k127_1663923_20 1408164.MOLA814_00096 1.859e-46 174.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria,1KR30@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria Q DSBA-like thioredoxin domain - - - - - - - - - - - - DSBA DYD2_k127_1663923_15 1274524.BSONL12_15424 4.943e-75 262.0 COG1028@1|root,COG1028@2|Bacteria,1UV9Q@1239|Firmicutes,4HAQ0@91061|Bacilli,1ZQ6D@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family yvrD - - - - - - - - - - - adh_short,adh_short_C2 DYD2_k127_1663923_1 670487.Ocepr_2129 3.354e-250 782.0 COG0318@1|root,COG0318@2|Bacteria,1WIB8@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C DYD2_k127_1663923_23 1301098.PKB_4325 1.967e-30 123.0 COG4274@1|root,COG4274@2|Bacteria,1RHJ3@1224|Proteobacteria 1224|Proteobacteria S GYD domain - - - - - - - - - - - - GYD DYD2_k127_1663923_4 1192034.CAP_4131 6.158e-212 672.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42PZH@68525|delta/epsilon subdivisions,2WJ0T@28221|Deltaproteobacteria,2YTTX@29|Myxococcales 28221|Deltaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M DYD2_k127_1663923_21 1288494.EBAPG3_7510 2.513e-46 171.0 COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,373EC@32003|Nitrosomonadales 28216|Betaproteobacteria L HNH nucleases - - - - - - - - - - - - HNH DYD2_k127_1663923_19 1123401.JHYQ01000047_gene162 8.026e-56 201.0 COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,1S8DJ@1236|Gammaproteobacteria,463PP@72273|Thiotrichales 72273|Thiotrichales O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C,GST_N DYD2_k127_1663923_14 1123023.JIAI01000004_gene7902 4.036e-75 263.0 COG0329@1|root,COG0329@2|Bacteria 2|Bacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - 3.5.4.22,4.3.3.7 ko:K01714,ko:K21062 ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R02280,R10147 RC00679,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD2_k127_1663923_24 292.DM42_5219 1.335e-27 124.0 COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,2VQSK@28216|Betaproteobacteria,1K5XP@119060|Burkholderiaceae 28216|Betaproteobacteria EM Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD2_k127_1663923_18 1120983.KB894572_gene2925 1.576e-63 228.0 COG1028@1|root,COG1028@2|Bacteria,1MX6D@1224|Proteobacteria,2TV8J@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 DYD2_k127_1663923_7 1123501.KB902294_gene3538 1.109e-116 390.0 COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE PrpD family protein - - - - - - - - - - - - MmgE_PrpD DYD2_k127_1688613_1 338969.Rfer_2185 2.668e-100 332.0 COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria,4AH00@80864|Comamonadaceae 28216|Betaproteobacteria C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain porB - 1.2.1.58,1.2.7.1 ko:K00170,ko:K18356 ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R02450,R08034 RC00004,RC00250,RC02742,RC02833,RC02860 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer4_11,Fer4_6,TPP_enzyme_C DYD2_k127_1688613_0 1454004.AW11_01657 4.493e-305 941.0 COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria 28216|Betaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3 DYD2_k127_1688613_2 497321.C664_15333 2.394e-99 330.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VK64@28216|Betaproteobacteria,2KUKM@206389|Rhodocyclales 206389|Rhodocyclales G HpcH/HpaI aldolase/citrate lyase family - - 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 - R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI DYD2_k127_1688613_3 1207063.P24_05877 1.76e-19 88.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JQ5K@204441|Rhodospirillales 204441|Rhodospirillales EG Belongs to the IlvD Edd family - - 4.2.1.82,4.2.1.9 ko:K01687,ko:K22186 ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R02429,R04441,R05070 RC00468,RC00543,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD2_k127_1704283_0 261292.Nit79A3_1931 1.913e-181 573.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,372Q8@32003|Nitrosomonadales 28216|Betaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD2_k127_1704283_1 1266925.JHVX01000003_gene607 5.795e-150 500.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VZIT@28216|Betaproteobacteria,371QJ@32003|Nitrosomonadales 28216|Betaproteobacteria O Trypsin - - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD2_k127_1704283_2 159087.Daro_4183 3.518e-82 283.0 COG3971@1|root,COG3971@2|Bacteria,1R3UP@1224|Proteobacteria,2VNA2@28216|Betaproteobacteria 28216|Betaproteobacteria Q hydratase decarboxylase - - - - - - - - - - - - - DYD2_k127_1704283_3 1205680.CAKO01000007_gene4312 1.313e-74 271.0 COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales 204441|Rhodospirillales Q Taurine catabolism dioxygenase TauD, TfdA family tauD - 1.14.11.17 ko:K03119,ko:K22303 ko00430,ko00920,map00430,map00920 - R05320 RC01331 ko00000,ko00001,ko01000 - - - TauD DYD2_k127_1704447_18 1121861.KB899913_gene2284 1.354e-87 297.0 COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2U0AF@28211|Alphaproteobacteria 28211|Alphaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD2_k127_1704447_4 1178482.BJB45_03275 1.255e-142 464.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1XHM9@135619|Oceanospirillales 135619|Oceanospirillales G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH DYD2_k127_1704447_34 1178482.BJB45_03270 2.553e-34 139.0 COG2863@1|root,COG2863@2|Bacteria,1RC1Y@1224|Proteobacteria,1S9J7@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG2863 Cytochrome c553 - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD2_k127_1704447_39 1232410.KI421412_gene154 8.506e-05 49.0 292XF@1|root,2ZQEX@2|Bacteria,1P8W2@1224|Proteobacteria,432F4@68525|delta/epsilon subdivisions,2WXUJ@28221|Deltaproteobacteria,43VN9@69541|Desulfuromonadales 28221|Deltaproteobacteria S PilZ domain - - - - - - - - - - - - PilZ DYD2_k127_1704447_6 1429916.X566_18495 2.47e-131 432.0 COG0477@1|root,COG2814@2|Bacteria,1P3S4@1224|Proteobacteria,2TVAQ@28211|Alphaproteobacteria,3JTFE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 DYD2_k127_1704447_19 525904.Tter_0266 3.832e-76 286.0 COG4262@1|root,COG4262@2|Bacteria,2NS3W@2323|unclassified Bacteria 2|Bacteria S Spermine/spermidine synthase domain - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - MFS_1,Spermine_synth DYD2_k127_1704447_5 1429916.X566_16715 1.319e-133 437.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3JQNX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD2_k127_1704447_37 1163409.UUA_10136 2.57e-09 61.0 2CE2X@1|root,32RZ0@2|Bacteria,1N2A4@1224|Proteobacteria,1SBRW@1236|Gammaproteobacteria,1XB4Z@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD2_k127_1704447_0 1380394.JADL01000005_gene5545 5.604e-201 632.0 COG1058@1|root,COG1058@2|Bacteria,1QUB2@1224|Proteobacteria 1224|Proteobacteria S Belongs to the CinA family yfaY - - - - - - - - - - - MoCF_biosynth DYD2_k127_1704447_1 1122609.AUGT01000023_gene576 2.15e-190 609.0 COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,4DUUR@85009|Propionibacteriales 201174|Actinobacteria EH Thiamine pyrophosphate enzyme, central domain - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_1704447_31 1463861.JNXE01000041_gene7895 4.746e-38 150.0 COG3427@1|root,COG3427@2|Bacteria,2IJBQ@201174|Actinobacteria 201174|Actinobacteria S Carbon monoxide dehydrogenase subunit G (CoxG) - - - - - - - - - - - - COXG DYD2_k127_1704447_21 397945.Aave_0200 4.709e-73 258.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4AAJP@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_1704447_16 768671.ThimaDRAFT_1867 1.934e-93 317.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1WWUF@135613|Chromatiales 135613|Chromatiales S PFAM Patatin - - - ko:K07001 - - - - ko00000 - - - Patatin DYD2_k127_1704447_7 1207063.P24_02186 7.439e-130 430.0 COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,2TSKZ@28211|Alphaproteobacteria,2JPNM@204441|Rhodospirillales 204441|Rhodospirillales V COG0534 Na -driven multidrug efflux pump - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD2_k127_1704447_30 1123261.AXDW01000009_gene154 4.077e-40 152.0 COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,1S3PN@1236|Gammaproteobacteria,1X84I@135614|Xanthomonadales 135614|Xanthomonadales S MAPEG family - - - - - - - - - - - - MAPEG DYD2_k127_1704447_35 285535.JOEY01000127_gene5834 6.377e-15 87.0 COG1878@1|root,COG1878@2|Bacteria,2I8ZI@201174|Actinobacteria 201174|Actinobacteria S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation - - - - - - - - - - - - Cyclase DYD2_k127_1704447_9 1336249.JADW01000004_gene3420 9.291e-118 390.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,4BGFP@82115|Rhizobiaceae 28211|Alphaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase DYD2_k127_1704447_3 85643.Tmz1t_1704 5.533e-148 481.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,2VMTR@28216|Betaproteobacteria,2KY0M@206389|Rhodocyclales 206389|Rhodocyclales M COG2951 Membrane-bound lytic murein transglycosylase B - - - - - - - - - - - - PG_binding_1,SLT_2 DYD2_k127_1704447_29 399795.CtesDRAFT_PD2957 4.613e-41 156.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,4AEN7@80864|Comamonadaceae 28216|Betaproteobacteria S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC DYD2_k127_1704447_14 1382304.JNIL01000001_gene1346 7.218e-97 326.0 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,279TN@186823|Alicyclobacillaceae 91061|Bacilli Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase DYD2_k127_1704447_2 426117.M446_1228 4.153e-179 576.0 COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,1JX9Q@119045|Methylobacteriaceae 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_1704447_24 338969.Rfer_0847 1.677e-52 190.0 COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2VS54@28216|Betaproteobacteria,4AE2P@80864|Comamonadaceae 28216|Betaproteobacteria S Domain of unknown function (DUF1993) - - - ko:K09983 - - - - ko00000 - - - DUF1993 DYD2_k127_1704447_15 414684.RC1_3371 1.064e-94 323.0 COG0627@1|root,COG0627@2|Bacteria,1QIRQ@1224|Proteobacteria,2TUU5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative esterase - - - - - - - - - - - - Esterase DYD2_k127_1704447_25 1173021.ALWA01000012_gene1164 2.167e-50 198.0 COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1FZWU@1117|Cyanobacteria 1117|Cyanobacteria T Diguanylate cyclase with PAS PAC and GAF sensors - - - - - - - - - - - - GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_9 DYD2_k127_1704447_20 331869.BAL199_22237 4.69e-75 265.0 COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,2TR13@28211|Alphaproteobacteria,4BQV1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_1704447_12 1042209.HK44_011055 3.45e-108 358.0 COG0583@1|root,COG0583@2|Bacteria,1MWUD@1224|Proteobacteria,1S5SM@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_1704447_10 1123393.KB891316_gene1673 2.254e-113 373.0 COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2VJ2X@28216|Betaproteobacteria,1KS7C@119069|Hydrogenophilales 119069|Hydrogenophilales C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB DYD2_k127_1704447_13 292415.Tbd_2349 3.995e-107 353.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VJSK@28216|Betaproteobacteria,1KSC0@119069|Hydrogenophilales 119069|Hydrogenophilales S Oxidoreductase molybdopterin binding domain - - - - - - - - - - - - Oxidored_molyb DYD2_k127_1704447_11 1216976.AX27061_2540 1.463e-110 362.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,3T2BC@506|Alcaligenaceae 28216|Betaproteobacteria O Belongs to the GST superfamily - - 2.5.1.18 ko:K00799,ko:K11209 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N DYD2_k127_1704447_23 765912.Thimo_1373 9.573e-67 237.0 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,1S834@1236|Gammaproteobacteria,1X1BH@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF1223) - - - - - - - - - - - - DUF1223 DYD2_k127_1704447_36 159087.Daro_1517 6.227e-14 74.0 29WPJ@1|root,30IAG@2|Bacteria,1PJEQ@1224|Proteobacteria,2WASB@28216|Betaproteobacteria,2KZKH@206389|Rhodocyclales 159087.Daro_1517|- - - - - - - - - - - - - - - - DYD2_k127_1704447_32 1173263.Syn7502_00339 4.791e-35 139.0 COG2020@1|root,COG2020@2|Bacteria,1GB2G@1117|Cyanobacteria 1117|Cyanobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - PEMT DYD2_k127_1704447_17 697282.Mettu_4180 2.55e-89 297.0 COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,1S6MP@1236|Gammaproteobacteria,1XF7P@135618|Methylococcales 135618|Methylococcales S Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_1704447_28 1458275.AZ34_08150 3.07e-45 175.0 COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,2VNP3@28216|Betaproteobacteria,4ACVX@80864|Comamonadaceae 28216|Betaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 DYD2_k127_1704447_26 292.DM42_6078 8.27e-48 181.0 COG0346@1|root,COG0346@2|Bacteria,1RGVH@1224|Proteobacteria,2W3WX@28216|Betaproteobacteria,1K8W6@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD2_k127_1704447_22 196367.JNFG01000214_gene981 1.649e-69 242.0 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2VK8F@28216|Betaproteobacteria,1JZYT@119060|Burkholderiaceae 28216|Betaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - 1-cysPrx_C,AhpC-TSA DYD2_k127_1704447_27 497321.C664_07178 2.271e-46 171.0 COG4273@1|root,COG4273@2|Bacteria,1MZN7@1224|Proteobacteria,2W34Q@28216|Betaproteobacteria,2KZ1R@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function (DUF2703) - - - - - - - - - - - - DUF2703 DYD2_k127_1704447_38 411902.CLOBOL_01805 9.021e-07 60.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - 5.3.3.19 ko:K19547 ko01130,map01130 M00787 - - ko00000,ko00001,ko00002,ko01000 - - - Cupin_2 DYD2_k127_1704447_33 595537.Varpa_2356 2.552e-34 134.0 COG5470@1|root,COG5470@2|Bacteria,1N012@1224|Proteobacteria,2WFG0@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 DYD2_k127_1704447_8 748280.NH8B_1614 5.847e-121 393.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VJM9@28216|Betaproteobacteria,2KQZC@206351|Neisseriales 206351|Neisseriales P Binding-protein-dependent transport system inner membrane component - - - ko:K15552 ko00920,ko02010,map00920,map02010 M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.1,3.A.1.17.4 - - BPD_transp_1 DYD2_k127_1718010_20 1392838.AWNM01000020_gene3859 1.814e-19 92.0 COG0684@1|root,COG0684@2|Bacteria 2|Bacteria H ribonuclease inhibitor activity - - - - - - - - - - - - RraA-like DYD2_k127_1718010_0 1207063.P24_01946 9.121e-265 825.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JUXN@204441|Rhodospirillales 204441|Rhodospirillales EG Belongs to the IlvD Edd family - - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD2_k127_1718010_14 864051.BurJ1DRAFT_0250 4.887e-50 184.0 COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2VR5U@28216|Betaproteobacteria,1KKW9@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Cysteine-rich motif following a subset of SET domains - - - ko:K07117 - - - - ko00000 - - - SET DYD2_k127_1718010_10 1036674.A28LD_1455 2.937e-68 250.0 COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,1RYM6@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD2_k127_1718010_21 479434.Sthe_2947 4.868e-19 94.0 COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi 200795|Chloroflexi CH Flavodoxin domain - - 1.3.5.3 ko:K00230 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R09489 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Flavodoxin_5 DYD2_k127_1718010_8 1036674.A28LD_1455 2.09e-85 299.0 COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,1RYM6@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD2_k127_1718010_4 395493.BegalDRAFT_3217 1.763e-110 369.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,45ZWY@72273|Thiotrichales 72273|Thiotrichales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP DYD2_k127_1718010_15 318996.AXAZ01000095_gene4941 5.313e-46 183.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind DYD2_k127_1718010_1 1173027.Mic7113_4161 6.142e-156 535.0 COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,Response_reg DYD2_k127_1718010_16 272134.KB731324_gene6220 3.109e-40 152.0 COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria,1HBXB@1150|Oscillatoriales 1117|Cyanobacteria T Response regulator receiver - - - - - - - - - - - - Response_reg DYD2_k127_1718010_13 1500301.JQMF01000005_gene3809 9.246e-51 185.0 COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,4BFWW@82115|Rhizobiaceae 28211|Alphaproteobacteria KT cheY-homologous receiver domain divK - - ko:K11443 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg DYD2_k127_1718010_7 639283.Snov_2000 2.305e-90 312.0 COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,2TS77@28211|Alphaproteobacteria,3F2C8@335928|Xanthobacteraceae 28211|Alphaproteobacteria T Sigma factor PP2C-like phosphatases - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - HATPase_c_2,Response_reg,SpoIIE DYD2_k127_1718010_18 1380394.JADL01000003_gene4839 1.805e-27 124.0 COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria,2JTM5@204441|Rhodospirillales 204441|Rhodospirillales T Histidine kinase-like ATPase domain - - - - - - - - - - - - HATPase_c_2 DYD2_k127_1718010_19 177437.HRM2_41220 2.044e-21 98.0 COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42V1I@68525|delta/epsilon subdivisions,2WRH0@28221|Deltaproteobacteria,2MKP1@213118|Desulfobacterales 28221|Deltaproteobacteria T STAS domain - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS DYD2_k127_1718010_2 370438.PTH_2271 8.883e-130 436.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia 186801|Clostridia F Psort location CytoplasmicMembrane, score 10.00 - - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease DYD2_k127_1718010_9 370438.PTH_2271 2.25e-80 279.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia 186801|Clostridia F Psort location CytoplasmicMembrane, score 10.00 - - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease DYD2_k127_1718010_12 370438.PTH_2271 1.49e-58 215.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia 186801|Clostridia F Psort location CytoplasmicMembrane, score 10.00 - - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease DYD2_k127_1718010_3 370438.PTH_2271 5.482e-125 420.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia 186801|Clostridia F Psort location CytoplasmicMembrane, score 10.00 - - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease DYD2_k127_1718010_11 555079.Toce_0381 6.444e-61 227.0 COG3135@1|root,COG3135@2|Bacteria,1UFIU@1239|Firmicutes,248XX@186801|Clostridia,42G3G@68295|Thermoanaerobacterales 186801|Clostridia Q Benzoate membrane transport protein - - - ko:K05782 - - - - ko00000,ko02000 2.A.46.1 - - BenE DYD2_k127_1718010_5 520709.F985_00883 2.027e-100 332.0 COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,1S3IM@1236|Gammaproteobacteria,3NST6@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1003) - - - - - - - - - - - - DUF1003 DYD2_k127_1718010_6 948106.AWZT01000001_gene5083 4.755e-99 330.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VNR6@28216|Betaproteobacteria,1K9QW@119060|Burkholderiaceae 28216|Betaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD2_k127_1718010_17 948106.AWZT01000001_gene5084 2.284e-33 133.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,1K1D1@119060|Burkholderiaceae 28216|Betaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_172867_12 1118054.CAGW01000061_gene2426 7.976e-40 150.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,26RRC@186822|Paenibacillaceae 91061|Bacilli E ABC transporter - - - - - - - - - - - - ABC_tran DYD2_k127_172867_20 190486.XAC0531 2.11e-19 92.0 2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,1SCKY@1236|Gammaproteobacteria,1X875@135614|Xanthomonadales 135614|Xanthomonadales S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP DYD2_k127_172867_2 365046.Rta_29320 7.877e-79 275.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJCY@28216|Betaproteobacteria,4ABM4@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_172867_15 383407.XOC_4659 1.449e-34 141.0 COG1787@1|root,COG1787@2|Bacteria,1RAHG@1224|Proteobacteria,1RYIV@1236|Gammaproteobacteria,1X6AQ@135614|Xanthomonadales 135614|Xanthomonadales V Restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_cat,zf-C4_Topoisom DYD2_k127_172867_0 1123242.JH636434_gene3342 7.892e-111 365.0 COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes 203682|Planctomycetes F ATP phosphoribosyltransferase hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C DYD2_k127_172867_1 237368.SCABRO_00086 1.084e-81 278.0 COG2887@1|root,COG2887@2|Bacteria 2|Bacteria L Belongs to the helicase family. UvrD subfamily - - 3.6.4.12 ko:K10742 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - AAA_24,PDDEXK_1 DYD2_k127_172867_19 1385515.N791_03520 8.501e-20 94.0 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,1X82S@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD2_k127_172867_7 292415.Tbd_1110 5.131e-64 234.0 COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,2VQ1F@28216|Betaproteobacteria 28216|Betaproteobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2,TPR_16,TPR_17 DYD2_k127_172867_23 1101190.ARWB01000001_gene2920 0.0001663 53.0 COG5485@1|root,COG5485@2|Bacteria,1NG9D@1224|Proteobacteria 1224|Proteobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL DYD2_k127_172867_21 1173020.Cha6605_3000 5.507e-13 81.0 COG5485@1|root,COG5485@2|Bacteria,1G620@1117|Cyanobacteria 1117|Cyanobacteria S PFAM SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL DYD2_k127_172867_22 56780.SYN_01247 6.772e-06 52.0 2DCXT@1|root,2ZFR8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_172867_13 448385.sce6817 8.76e-39 152.0 COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria 1224|Proteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA DYD2_k127_172867_17 1385935.N836_03140 9.395e-30 123.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase,Glyoxalase_4 DYD2_k127_172867_16 1123514.KB905899_gene1192 3.612e-31 127.0 2C3Q0@1|root,334WS@2|Bacteria,1NBS8@1224|Proteobacteria,1SE5H@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - IV02_14570 - - - - - - - - - - - - DYD2_k127_172867_9 1122604.JONR01000039_gene3753 1.908e-57 203.0 COG4696@1|root,COG4696@2|Bacteria,1N92T@1224|Proteobacteria,1SP95@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - DYD2_k127_172867_11 264198.Reut_C6210 2.492e-54 207.0 COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2VX9A@28216|Betaproteobacteria 28216|Betaproteobacteria S Prolyl oligopeptidase family - - - - - - - - - - - - DUF1100,Peptidase_S9 DYD2_k127_172867_6 319003.Bra1253DRAFT_02078 3.219e-74 261.0 COG0604@1|root,COG0604@2|Bacteria,1QSVA@1224|Proteobacteria,2U1AA@28211|Alphaproteobacteria,3JVX7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_172867_5 713587.THITH_08925 3.141e-75 265.0 COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria 2|Bacteria S quinone binding - - 3.5.1.104 ko:K12057,ko:K22278 - - - - ko00000,ko01000,ko02044 3.A.7.11.1 - - Thioredoxin_4,VKOR DYD2_k127_172867_18 1380394.JADL01000002_gene1250 1.606e-26 113.0 2DWFS@1|root,32V1J@2|Bacteria,1MZ9A@1224|Proteobacteria,2UDME@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Nitrile hydratase beta subunit - - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta DYD2_k127_172867_14 1380394.JADL01000002_gene1249 1.356e-38 151.0 2DBV6@1|root,32TY6@2|Bacteria,1N0TC@1224|Proteobacteria,2UCAJ@28211|Alphaproteobacteria,2JXVR@204441|Rhodospirillales 204441|Rhodospirillales S Nitrile hydratase beta subunit - - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta DYD2_k127_172867_4 1288298.rosmuc_02668 1.346e-76 263.0 2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,46QCF@74030|Roseovarius 28211|Alphaproteobacteria S Nitrile hydratase, alpha chain nthA - 4.2.1.84 ko:K01721,ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R02828,R04020,R05379,R05596,R07780,R07854 RC00483,RC00792,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_alpha DYD2_k127_172867_10 1173024.KI912151_gene1639 5.494e-57 205.0 COG1309@1|root,COG1309@2|Bacteria,1G5IR@1117|Cyanobacteria,1JKA7@1189|Stigonemataceae 1117|Cyanobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N DYD2_k127_172867_8 394221.Mmar10_1233 1.92e-59 215.0 COG0500@1|root,COG3000@1|root,COG2226@2|Bacteria,COG3000@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,43XEV@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD2_k127_172867_3 1430440.MGMSRv2_3680 3.497e-77 277.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,2JPD5@204441|Rhodospirillales 204441|Rhodospirillales V MatE norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD2_k127_1786985_80 338969.Rfer_3176 0.0009687 42.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,4A9RX@80864|Comamonadaceae 28216|Betaproteobacteria L PFAM AAA ATPase central domain protein rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N DYD2_k127_1786985_15 1175306.GWL_13530 1.125e-184 590.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,473JN@75682|Oxalobacteraceae 28216|Betaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b DYD2_k127_1786985_78 1207063.P24_17558 7.865e-05 48.0 COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria,2JW58@204441|Rhodospirillales 204441|Rhodospirillales L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Resolvase DYD2_k127_1786985_35 419610.Mext_3859 2.991e-98 329.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD2_k127_1786985_33 441620.Mpop_4316 1.113e-102 351.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria,1JRBF@119045|Methylobacteriaceae 28211|Alphaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC DYD2_k127_1786985_56 1328313.DS2_01988 7.348e-50 187.0 COG2095@1|root,COG2095@2|Bacteria,1RAFQ@1224|Proteobacteria,1S2XM@1236|Gammaproteobacteria,46CEI@72275|Alteromonadaceae 1236|Gammaproteobacteria U MarC family integral membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD2_k127_1786985_62 1249627.D779_1479 3.864e-37 148.0 COG0586@1|root,COG0586@2|Bacteria,1PE6E@1224|Proteobacteria,1RW0D@1236|Gammaproteobacteria,1WZ1I@135613|Chromatiales 135613|Chromatiales I PFAM SNARE associated Golgi protein - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - SNARE_assoc DYD2_k127_1786985_58 330214.NIDE2604 2.383e-43 167.0 28PW7@1|root,32EDN@2|Bacteria 2|Bacteria S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 DYD2_k127_1786985_41 296591.Bpro_0408 5.639e-82 274.0 COG1839@1|root,COG1839@2|Bacteria,1RBCB@1224|Proteobacteria,2VQUB@28216|Betaproteobacteria 28216|Betaproteobacteria S Adenosine specific kinase - - - ko:K09129 - - - - ko00000 - - - Adenosine_kin DYD2_k127_1786985_24 1266925.JHVX01000003_gene396 9.671e-146 470.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,372AK@32003|Nitrosomonadales 28216|Betaproteobacteria P Belongs to the ABC transporter superfamily fbpC - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 DYD2_k127_1786985_8 1304883.KI912532_gene3010 3.431e-209 664.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,2KVS9@206389|Rhodocyclales 206389|Rhodocyclales P ABC-type Fe3 transport system, permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD2_k127_1786985_26 388051.AUFE01000006_gene1325 5.453e-140 452.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1JZVS@119060|Burkholderiaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein fbpA - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 DYD2_k127_1786985_61 1218074.BAXZ01000026_gene4594 4.963e-41 156.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VRPY@28216|Betaproteobacteria,1K4T6@119060|Burkholderiaceae 28216|Betaproteobacteria M PFAM NLP P60 protein - - - - - - - - - - - - NLPC_P60 DYD2_k127_1786985_53 640081.Dsui_2222 4.915e-55 205.0 COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,2WGZA@28216|Betaproteobacteria,2KWAH@206389|Rhodocyclales 206389|Rhodocyclales U Bacterial type II and III secretion system protein - - - - - - - - - - - - Secretin DYD2_k127_1786985_72 497964.CfE428DRAFT_2422 3.71e-19 98.0 COG4194@1|root,COG4194@2|Bacteria 2|Bacteria K SdpI/YhfL protein family - - - - - - - - - - - - DUF1648 DYD2_k127_1786985_5 1485544.JQKP01000018_gene577 3.461e-253 798.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,44VAI@713636|Nitrosomonadales 28216|Betaproteobacteria L HELICc2 dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_2,Helicase_C_2,ResIII DYD2_k127_1786985_7 1163617.SCD_n01841 3.307e-225 707.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 DYD2_k127_1786985_46 1000565.METUNv1_00467 2.194e-70 246.0 COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2VJ2N@28216|Betaproteobacteria,2KVGG@206389|Rhodocyclales 206389|Rhodocyclales S synthesis repressor, PhaR - - - - - - - - - - - - PHB_acc,PHB_acc_N DYD2_k127_1786985_28 375286.mma_0556 4.507e-122 396.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,473C7@75682|Oxalobacteraceae 28216|Betaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family phbB - 1.1.1.36 ko:K00023 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R01779,R01977 RC00103,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 DYD2_k127_1786985_14 159087.Daro_1608 7.012e-192 623.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KUWX@206389|Rhodocyclales 206389|Rhodocyclales I Poly(R)-hydroxyalkanoic acid synthase, class I - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - PhaC_N DYD2_k127_1786985_40 748247.AZKH_3142 7.574e-84 285.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,2KUES@206389|Rhodocyclales 206389|Rhodocyclales S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 DYD2_k127_1786985_29 323848.Nmul_A1976 4.157e-116 383.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,371YJ@32003|Nitrosomonadales 28216|Betaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD2_k127_1786985_31 522306.CAP2UW1_3923 1.215e-110 363.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KQ3X@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamD - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO DYD2_k127_1786985_39 1122947.FR7_2687 1.003e-87 299.0 COG0697@1|root,COG0697@2|Bacteria,1V230@1239|Firmicutes,4H6TY@909932|Negativicutes 909932|Negativicutes EG EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_1786985_67 1000565.METUNv1_02630 2.32e-31 131.0 COG3133@1|root,COG3133@2|Bacteria,1RK6D@1224|Proteobacteria,2VU04@28216|Betaproteobacteria,2KWUY@206389|Rhodocyclales 206389|Rhodocyclales M Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti DYD2_k127_1786985_2 62928.azo2149 2.603e-303 941.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2VKAN@28216|Betaproteobacteria,2KVQH@206389|Rhodocyclales 206389|Rhodocyclales I Acetyl-coenzyme A synthetase N-terminus acsA - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD2_k127_1786985_11 1266925.JHVX01000012_gene1712 1.45e-203 645.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,3727P@32003|Nitrosomonadales 28216|Betaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon DYD2_k127_1786985_17 1163617.SCD_n01826 1.738e-178 571.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria 28216|Betaproteobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD2_k127_1786985_71 666685.R2APBS1_3674 1.207e-23 113.0 2E4BS@1|root,32Z7C@2|Bacteria,1NBM8@1224|Proteobacteria,1T50K@1236|Gammaproteobacteria,1X8D0@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD2_k127_1786985_70 292415.Tbd_1946 6.979e-25 111.0 2EV5S@1|root,33NKJ@2|Bacteria,1NI0N@1224|Proteobacteria,2VYM4@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3568) - - - - - - - - - - - - DUF3568 DYD2_k127_1786985_13 261292.Nit79A3_0197 2.392e-196 629.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,371XW@32003|Nitrosomonadales 28216|Betaproteobacteria L DHH family recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD2_k127_1786985_50 1266925.JHVX01000010_gene1397 2.373e-61 226.0 COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria,3729Q@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - PhosphMutase DYD2_k127_1786985_22 323848.Nmul_A2509 5.579e-162 519.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,372GX@32003|Nitrosomonadales 28216|Betaproteobacteria M TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD DYD2_k127_1786985_36 1163617.SCD_n01098 7.039e-97 321.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria 28216|Betaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran DYD2_k127_1786985_79 296591.Bpro_1724 0.0003244 48.0 2CE4Y@1|root,34C4Z@2|Bacteria,1P3HD@1224|Proteobacteria,2W4H6@28216|Betaproteobacteria,4AI8C@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_1786985_47 1454004.AW11_03134 3.496e-68 246.0 COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2VHMQ@28216|Betaproteobacteria,1KPY7@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria L DNA replication, recombination and repair alkA - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD DYD2_k127_1786985_49 323848.Nmul_A2507 2.01e-61 218.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,3732Y@32003|Nitrosomonadales 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2062) - - - ko:K09928 - - - - ko00000 - - - DUF2062 DYD2_k127_1786985_4 1163617.SCD_n01103 4.277e-263 835.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria 28216|Betaproteobacteria S DNA internalization-related competence protein ComEC Rec2 comA - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B DYD2_k127_1786985_20 1163617.SCD_n00033 2.761e-170 546.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,2VI7F@28216|Betaproteobacteria 28216|Betaproteobacteria P Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD2_k127_1786985_42 1449126.JQKL01000016_gene2860 1.754e-77 264.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,249EP@186801|Clostridia 186801|Clostridia L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco DYD2_k127_1786985_66 522306.CAP2UW1_0608 1.795e-32 141.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,1KQ7E@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S Circularly permuted ATP-grasp type 2 - - - - - - - - - - - - CP_ATPgrasp_2 DYD2_k127_1786985_6 1288494.EBAPG3_28580 4.707e-235 749.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,372M8@32003|Nitrosomonadales 28216|Betaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS DYD2_k127_1786985_48 1122603.ATVI01000005_gene3042 5.112e-67 237.0 COG0668@1|root,COG0668@2|Bacteria,1N4UN@1224|Proteobacteria,1T9TX@1236|Gammaproteobacteria,1XBUR@135614|Xanthomonadales 135614|Xanthomonadales M Conserved TM helix - - - - - - - - - - - - MS_channel,TM_helix DYD2_k127_1786985_59 1122603.ATVI01000005_gene3041 6.627e-43 169.0 COG2239@1|root,COG2239@2|Bacteria,1NNAQ@1224|Proteobacteria,1SHM4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P MgtE intracellular N domain - - - - - - - - - - - - CBS,MgtE_N DYD2_k127_1786985_25 1122603.ATVI01000005_gene3040 1.04e-141 462.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD2_k127_1786985_51 375286.mma_0313 7.141e-60 217.0 COG3971@1|root,COG3971@2|Bacteria,1RGHI@1224|Proteobacteria,2VRTF@28216|Betaproteobacteria,473R4@75682|Oxalobacteraceae 28216|Betaproteobacteria Q 2-keto-4-pentenoate hydratase mhpD - - - - - - - - - - - FAA_hydrolase DYD2_k127_1786985_52 391595.RLO149_c008070 8.811e-59 213.0 COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,2TRJH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Formylglycine-generating sulfatase enzyme - - 1.14.99.50 ko:K18912,ko:K20333 ko00340,ko02024,map00340,map02024 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - FGE-sulfatase DYD2_k127_1786985_68 1040987.AZUY01000019_gene1355 3.507e-30 121.0 COG5470@1|root,COG5470@2|Bacteria,1PJHZ@1224|Proteobacteria,2UDNK@28211|Alphaproteobacteria,43QKC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 DYD2_k127_1786985_1 1288494.EBAPG3_4460 1.01e-321 996.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,371Z6@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD DYD2_k127_1786985_44 580332.Slit_1736 9.272e-73 252.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,44VQU@713636|Nitrosomonadales 28216|Betaproteobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N DYD2_k127_1786985_73 76114.ebC8 7.915e-18 85.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,2KX60@206389|Rhodocyclales 206389|Rhodocyclales J Belongs to the bacterial ribosomal protein bL35 family rpmI - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p DYD2_k127_1786985_55 1288494.EBAPG3_4490 1.586e-51 184.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,3738Y@32003|Nitrosomonadales 28216|Betaproteobacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT - - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 DYD2_k127_1786985_23 1485544.JQKP01000010_gene829 9.523e-149 477.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,44VDW@713636|Nitrosomonadales 28216|Betaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d DYD2_k127_1786985_3 265072.Mfla_1998 1.686e-276 870.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,2KM1R@206350|Nitrosomonadales 206350|Nitrosomonadales J TIGRFAM phenylalanyl-tRNA synthetase, beta subunit pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind DYD2_k127_1786985_54 1266925.JHVX01000003_gene628 1.187e-51 186.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,373C7@32003|Nitrosomonadales 28216|Betaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA - - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD2_k127_1786985_57 667632.KB890172_gene3973 2.091e-48 175.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,1K7KJ@119060|Burkholderiaceae 28216|Betaproteobacteria K PFAM regulatory protein, MerR ycgE - - - - - - - - - - - MerR_1 DYD2_k127_1786985_75 351607.Acel_0895 2.05e-10 67.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity ynjA - - ko:K07486 - - - - ko00000 - - - CMD DYD2_k127_1786985_76 316274.Haur_1906 1.405e-05 51.0 COG2128@1|root,COG2128@2|Bacteria,2G7D8@200795|Chloroflexi,376E5@32061|Chloroflexia 32061|Chloroflexia S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD2_k127_1786985_63 1449065.JMLL01000010_gene1531 6.803e-37 145.0 COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria,43KNU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S protein possibly involved in utilization of glycolate and propanediol MA20_43165 - - - - - - - - - - - Haem_degrading DYD2_k127_1786985_38 570952.ATVH01000002_gene942 7.992e-89 301.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,2JQ0F@204441|Rhodospirillales 204441|Rhodospirillales S Carbon-nitrogen hydrolase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase DYD2_k127_1786985_30 292415.Tbd_0835 1.306e-113 370.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,1KRF6@119069|Hydrogenophilales 119069|Hydrogenophilales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD2_k127_1786985_43 1163617.SCD_n01118 2.825e-76 265.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD2_k127_1786985_45 640081.Dsui_1970 7.444e-72 254.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,2KU7R@206389|Rhodocyclales 206389|Rhodocyclales DM COG0739 Membrane proteins related to metalloendopeptidases - - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 DYD2_k127_1786985_12 1163617.SCD_n01285 5.68e-198 636.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria 28216|Betaproteobacteria E PFAM transglutaminase domain protein - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core DYD2_k127_1786985_37 1163617.SCD_n01286 1.325e-92 314.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria 28216|Betaproteobacteria S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 DYD2_k127_1786985_27 580332.Slit_2221 1.478e-126 413.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales 28216|Betaproteobacteria S PFAM ATPase associated with various cellular activities AAA_3 moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD2_k127_1786985_19 640081.Dsui_2394 1.153e-171 594.0 COG2202@1|root,COG3437@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVQ2@206389|Rhodocyclales 206389|Rhodocyclales T Response regulator receiver modulated diguanylate cyclase phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,Response_reg DYD2_k127_1786985_69 335283.Neut_0867 1.829e-27 121.0 COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,373I3@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF498/DUF598) - - - - - - - - - - - - DUF498 DYD2_k127_1786985_10 1007105.PT7_0474 1.046e-204 642.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VI7S@28216|Betaproteobacteria,3T1HH@506|Alcaligenaceae 28216|Betaproteobacteria E Aminotransferase alaC - - ko:K14261 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_1786985_9 1288494.EBAPG3_24940 2.875e-208 655.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,372HP@32003|Nitrosomonadales 28216|Betaproteobacteria E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 DYD2_k127_1786985_21 1286106.MPL1_12508 1.365e-164 524.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RWC8@1236|Gammaproteobacteria,460AJ@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - LeuA_dimer,PALP DYD2_k127_1786985_34 1485544.JQKP01000017_gene628 5.191e-101 336.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,44V18@713636|Nitrosomonadales 28216|Betaproteobacteria H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N DYD2_k127_1786985_18 1131553.JIBI01000046_gene1600 1.444e-176 569.0 COG2855@1|root,COG2855@2|Bacteria 2|Bacteria P membrane - - - - - - - - - - - - Cons_hypoth698 DYD2_k127_1786985_60 436229.JOEH01000051_gene6258 2.85e-41 160.0 29J25@1|root,305ZK@2|Bacteria,2IDE0@201174|Actinobacteria 201174|Actinobacteria S NIPSNAP - - - - - - - - - - - - NIPSNAP DYD2_k127_1786985_32 1265502.KB905931_gene1764 2.464e-106 356.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2VHSQ@28216|Betaproteobacteria,4AD1I@80864|Comamonadaceae 28216|Betaproteobacteria C cytochrome d ubiquinol oxidase, subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II DYD2_k127_1786985_16 1121013.P873_04755 1.898e-182 584.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,1X4FJ@135614|Xanthomonadales 135614|Xanthomonadales C oxidase, subunit - - - - - - - - - - - - Cyt_bd_oxida_I DYD2_k127_1786985_0 686340.Metal_0510 0.0 1114.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1XEP9@135618|Methylococcales 135618|Methylococcales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD2_k127_1832581_1 1205680.CAKO01000002_gene2508 3.759e-58 205.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TUWV@28211|Alphaproteobacteria,2JQWC@204441|Rhodospirillales 204441|Rhodospirillales E Pyridoxal-phosphate dependent enzyme - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_1832581_2 76114.ebA2569 9.14e-56 203.0 COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2VV97@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1499) - - - - - - - - - - - - DUF1499 DYD2_k127_1832581_5 1121405.dsmv_3313 4.423e-16 86.0 COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,42VD3@68525|delta/epsilon subdivisions,2WRQJ@28221|Deltaproteobacteria,2MNWQ@213118|Desulfobacterales 28221|Deltaproteobacteria S bacterial OsmY and nodulation domain - - - - - - - - - - - - BON DYD2_k127_1832581_3 395495.Lcho_4310 1.864e-45 177.0 COG0673@1|root,COG0673@2|Bacteria,1MUZI@1224|Proteobacteria,2VI1N@28216|Betaproteobacteria 28216|Betaproteobacteria S Oxidoreductase family, C-terminal alpha/beta domain - - 1.1.1.292 ko:K19181 - - - - ko00000,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_1832581_0 1038859.AXAU01000011_gene2483 6.801e-203 647.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - Guanylate_cyc,TPR_16,TPR_8,Trans_reg_C DYD2_k127_1832581_4 224911.27349765 3.786e-44 166.0 2FFVF@1|root,347SG@2|Bacteria,1RARH@1224|Proteobacteria,2U5R5@28211|Alphaproteobacteria,3JYJR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_1832581_7 1121106.JQKB01000016_gene5355 4.722e-07 51.0 2AJ2R@1|root,319M2@2|Bacteria,1RJXB@1224|Proteobacteria,2UA6I@28211|Alphaproteobacteria,2JY06@204441|Rhodospirillales 204441|Rhodospirillales S Conserved hypothetical protein (Lin0512_fam) - - - - - - - - - - - - Lin0512_fam DYD2_k127_1877500_1 365044.Pnap_0869 2.635e-62 228.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_1877500_0 859657.RPSI07_1426 4.111e-186 594.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,1K4ZW@119060|Burkholderiaceae 28216|Betaproteobacteria S 2-methylcitrate dehydratase prpD - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD DYD2_k127_1877500_3 879212.DespoDRAFT_01590 3.4e-41 174.0 28PR6@1|root,2ZCD4@2|Bacteria,1R8YU@1224|Proteobacteria,42QDY@68525|delta/epsilon subdivisions,2WKF1@28221|Deltaproteobacteria,2MJ84@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_1877500_2 331869.BAL199_17848 7.603e-54 193.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TUUN@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate - - 4.1.1.3 ko:K01003 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000 - - - PEP_mutase DYD2_k127_1973289_4 1538295.JY96_07740 6.198e-52 192.0 COG1309@1|root,COG1309@2|Bacteria,1N659@1224|Proteobacteria,2VS47@28216|Betaproteobacteria,1KMAF@119065|unclassified Burkholderiales 28216|Betaproteobacteria K MAATS-type transcriptional repressor, C-terminal region acrR - - ko:K03577 - M00647 - - ko00000,ko00002,ko03000 - - - TetR_C_2,TetR_N DYD2_k127_1973289_0 265072.Mfla_2074 0.0 1132.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,2KKET@206350|Nitrosomonadales 206350|Nitrosomonadales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD2_k127_1973289_3 1218084.BBJK01000068_gene4974 2.904e-61 215.0 COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQ1S@28216|Betaproteobacteria,1K30H@119060|Burkholderiaceae 28216|Betaproteobacteria K PFAM regulatory protein AsnC Lrp family - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 DYD2_k127_1973289_2 76114.ebA1369 1.198e-90 308.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK32@28216|Betaproteobacteria,2KZRT@206389|Rhodocyclales 206389|Rhodocyclales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_1973289_5 1123368.AUIS01000010_gene2379 1.737e-32 136.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane yqjF - - ko:K15977 - - - - ko00000 - - - DoxX DYD2_k127_1973289_1 396588.Tgr7_2043 7.318e-146 476.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNXA@1236|Gammaproteobacteria,1WWTQ@135613|Chromatiales 135613|Chromatiales E PFAM aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 DYD2_k127_2033594_8 1214242.B446_26060 2.187e-47 178.0 COG1011@1|root,COG1011@2|Bacteria,2GNSS@201174|Actinobacteria 201174|Actinobacteria S hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 DYD2_k127_2033594_6 1038859.AXAU01000028_gene27 1.266e-93 317.0 COG0410@1|root,COG0410@2|Bacteria,1R6QK@1224|Proteobacteria,2U82Z@28211|Alphaproteobacteria,3JZBP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD2_k127_2033594_5 1380355.JNIJ01000050_gene132 2.796e-99 332.0 COG0411@1|root,COG0411@2|Bacteria,1R5MA@1224|Proteobacteria,2TV7Q@28211|Alphaproteobacteria,3JZDF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD2_k127_2033594_3 1038859.AXAU01000028_gene25 1.409e-138 455.0 COG4177@1|root,COG4177@2|Bacteria,1N5I8@1224|Proteobacteria,2U0PT@28211|Alphaproteobacteria,3JSC7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD2_k127_2033594_4 1380355.JNIJ01000050_gene130 9.791e-115 376.0 COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2TTC6@28211|Alphaproteobacteria,3JSJ8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD2_k127_2033594_1 1380355.JNIJ01000050_gene128 4.235e-209 659.0 COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2TTAH@28211|Alphaproteobacteria,3JZY2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD2_k127_2033594_2 1038859.AXAU01000028_gene23 5.601e-143 480.0 COG3889@1|root,COG3889@2|Bacteria,1R6EI@1224|Proteobacteria,2UQR6@28211|Alphaproteobacteria,3K2HR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - - - - - - - - - - - DYD2_k127_2033594_7 279714.FuraDRAFT_1159 2.531e-53 192.0 COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,2VSIB@28216|Betaproteobacteria,2KT13@206351|Neisseriales 206351|Neisseriales S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 DYD2_k127_2033594_0 1232410.KI421420_gene3227 0.0 1430.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43U53@69541|Desulfuromonadales 28221|Deltaproteobacteria V AcrB/AcrD/AcrF family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran,OEP DYD2_k127_2060901_2 400682.PAC_15710332 2.954e-45 168.0 COG1132@1|root,KOG0055@2759|Eukaryota,39YRK@33154|Opisthokonta,3BN4Z@33208|Metazoa 33208|Metazoa Q atp-binding protein - - - - - - - - - - - - ABC_tran,oligo_HPY DYD2_k127_2060901_0 1038859.AXAU01000026_gene2328 2.922e-148 476.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,3JRF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD2_k127_2060901_4 1123368.AUIS01000009_gene2451 2.161e-25 111.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB DYD2_k127_2060901_1 228410.NE1937 6.395e-90 303.0 28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,2VZB8@28216|Betaproteobacteria,372HT@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF3750) - - - - - - - - - - - - DUF3750 DYD2_k127_2060901_6 1265502.KB905929_gene2207 6.524e-10 67.0 COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2VX5E@28216|Betaproteobacteria,4AJJ9@80864|Comamonadaceae 28216|Betaproteobacteria S SMART Transport-associated and nodulation - - - - - - - - - - - - BON DYD2_k127_2060901_5 177437.HRM2_03720 2.32e-17 87.0 COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,42VD3@68525|delta/epsilon subdivisions,2WRQJ@28221|Deltaproteobacteria,2MNWQ@213118|Desulfobacterales 28221|Deltaproteobacteria S bacterial OsmY and nodulation domain - - - - - - - - - - - - BON DYD2_k127_2060901_3 2340.JV46_22860 1.979e-32 133.0 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1J7BB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Phosphate-starvation-inducible E - - - ko:K13256 - - - - ko00000 - - - PsiE DYD2_k127_2072833_5 1288826.MSNKSG1_13762 2.776e-51 192.0 COG0491@1|root,COG0494@1|root,COG0491@2|Bacteria,COG0494@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria,46AP6@72275|Alteromonadaceae 1236|Gammaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes blaB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,NUDIX DYD2_k127_2072833_3 247633.GP2143_02120 7.075e-93 312.0 COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria,1J5PQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases blaB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B,NUDIX DYD2_k127_2072833_9 1283300.ATXB01000001_gene2119 4.835e-05 51.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XDZG@135618|Methylococcales 135618|Methylococcales U AMIN domain pilQ - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N DYD2_k127_2072833_8 911045.PSE_4618 9.238e-35 139.0 2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2072833_4 935548.KI912159_gene5420 5.731e-89 304.0 COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1QU5X@1224|Proteobacteria,2TW12@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - Abhydrolase_1,Guanylate_cyc DYD2_k127_2072833_2 1469245.JFBG01000080_gene290 1.226e-119 395.0 COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria 1224|Proteobacteria S TGS domain - - - ko:K06944 - - - - ko00000 - - - MMR_HSR1,TGS DYD2_k127_2072833_1 388051.AUFE01000058_gene5878 1.337e-125 419.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2VSMI@28216|Betaproteobacteria,1KGM6@119060|Burkholderiaceae 28216|Betaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_2072833_0 266265.Bxe_B0283 3.006e-184 592.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2W8ET@28216|Betaproteobacteria,1KCUI@119060|Burkholderiaceae 28216|Betaproteobacteria C FAD binding domain - - - ko:K13796 - - - - ko00000 - - - FAD_binding_2 DYD2_k127_2072833_7 1123075.AUDP01000037_gene168 2.154e-36 148.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae 186801|Clostridia IQ reductase srlD - 1.1.1.140,1.1.1.304,1.1.1.76 ko:K00068,ko:K03366 ko00051,ko00650,map00051,map00650 - R02855,R02946,R03707,R05607,R09078,R10505 RC00085,RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 DYD2_k127_2072833_6 1382304.JNIL01000001_gene3193 1.095e-36 145.0 COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,278UR@186823|Alicyclobacillaceae 91061|Bacilli IQ PFAM short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 DYD2_k127_2108644_5 1220582.RRU01S_28_00520 7.311e-37 142.0 COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,2TRQX@28211|Alphaproteobacteria,4BMQT@82115|Rhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_2108644_4 795666.MW7_0585 5.768e-75 263.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_2108644_2 331869.BAL199_29962 1.528e-86 300.0 COG0667@1|root,COG0667@2|Bacteria,1R5BH@1224|Proteobacteria,2TS0A@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD2_k127_2108644_3 1298867.AUES01000003_gene1238 2.322e-81 282.0 COG3181@1|root,COG3181@2|Bacteria,1P88K@1224|Proteobacteria,2TUJU@28211|Alphaproteobacteria,3JTW3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_2108644_6 1144310.PMI07_005554 3.934e-07 57.0 2D22U@1|root,32TC0@2|Bacteria,1N3XM@1224|Proteobacteria,2UC4N@28211|Alphaproteobacteria,4BN0W@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD2_k127_2108644_0 196490.AUEZ01000017_gene3196 9.371e-169 544.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family MA20_23145 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_2108644_1 1125973.JNLC01000011_gene602 1.182e-124 414.0 COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,3JW76@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_2108644_7 1449049.JONW01000008_gene415 5.35e-05 54.0 2FIJD@1|root,34ABE@2|Bacteria,1P2U7@1224|Proteobacteria,2UUK4@28211|Alphaproteobacteria,2KJ82@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - DYD2_k127_2180215_35 1121939.L861_19140 1.938e-39 166.0 2DMWA@1|root,32U36@2|Bacteria,1N1CC@1224|Proteobacteria,1SRZE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2180215_7 1122135.KB893135_gene973 3.527e-155 500.0 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD2_k127_2180215_6 314278.NB231_02358 2.529e-157 509.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1WZYF@135613|Chromatiales 135613|Chromatiales P Chromate transporter - - - - - - - - - - - - Chromate_transp DYD2_k127_2180215_37 1458357.BG58_18240 5.046e-34 139.0 COG1695@1|root,COG1695@2|Bacteria,1PWT8@1224|Proteobacteria,2WAGB@28216|Betaproteobacteria,1KF91@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - - DYD2_k127_2180215_17 1123393.KB891328_gene654 5.422e-87 298.0 COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria,1KSIP@119069|Hydrogenophilales 119069|Hydrogenophilales M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 DYD2_k127_2180215_8 404589.Anae109_0564 5.104e-146 474.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria 1224|Proteobacteria H Methyl-transferase egtB - 1.14.99.50 ko:K18912 ko00340,map00340 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - DinB_2,FGE-sulfatase DYD2_k127_2180215_14 1049564.TevJSym_ae00650 2.568e-97 325.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1J5P9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase DYD2_k127_2180215_19 1049564.TevJSym_ae00640 2.796e-81 276.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,1S2D9@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator, ArsR family - - - - - - - - - - - - HTH_20,HTH_5,Rhodanese DYD2_k127_2180215_41 1283300.ATXB01000001_gene778 3.198e-29 125.0 2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,1SAPM@1236|Gammaproteobacteria,1XGYA@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - DYD2_k127_2180215_9 365044.Pnap_4517 2.38e-133 444.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VJA1@28216|Betaproteobacteria 28216|Betaproteobacteria Q PFAM multicopper oxidase type sufI - 1.3.3.5 ko:K04753,ko:K08100,ko:K14588 ko00860,ko01110,map00860,map01110 - R02394 RC01983 ko00000,ko00001,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD2_k127_2180215_24 1122223.KB890696_gene397 4.866e-64 225.0 COG3485@1|root,COG3485@2|Bacteria 2|Bacteria Q protocatechuate 3,4-dioxygenase activity catA - 1.13.11.1 ko:K03381 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R00817,R04258,R05299,R08114,R08115,R09134 RC00388,RC00535,RC01366 ko00000,ko00001,ko00002,ko01000 - - - Dioxygenase_C DYD2_k127_2180215_22 472759.Nhal_3184 3.367e-69 241.0 COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,1T62V@1236|Gammaproteobacteria,1X277@135613|Chromatiales 135613|Chromatiales O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine - - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR DYD2_k127_2180215_10 365044.Pnap_4517 1.663e-129 433.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VJA1@28216|Betaproteobacteria 28216|Betaproteobacteria Q PFAM multicopper oxidase type sufI - 1.3.3.5 ko:K04753,ko:K08100,ko:K14588 ko00860,ko01110,map00860,map01110 - R02394 RC01983 ko00000,ko00001,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD2_k127_2180215_51 35703.DQ02_25200 5.213e-07 61.0 COG5569@1|root,COG5569@2|Bacteria,1N4KG@1224|Proteobacteria,1S9YP@1236|Gammaproteobacteria,3WYF5@544|Citrobacter 1236|Gammaproteobacteria S Copper binding periplasmic protein CusF cusF GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010272,GO:0010273,GO:0016530,GO:0016531,GO:0019725,GO:0030003,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042592,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0061687,GO:0065007,GO:0065008,GO:0097501,GO:0098754,GO:0098771,GO:0140104,GO:1990169 - ko:K07810 ko02020,map02020 - - - ko00000,ko00001 2.A.6.1.4 - iAF1260.b0573,iAPECO1_1312.APECO1_1475,iBWG_1329.BWG_0444,iE2348C_1286.E2348C_0473,iEC042_1314.EC042_0607,iECABU_c1320.ECABU_c06220,iECDH10B_1368.ECDH10B_0531,iECDH1ME8569_1439.ECDH1ME8569_0541,iECED1_1282.ECED1_0565,iECIAI39_1322.ECIAI39_0548,iECNA114_1301.ECNA114_0504,iECOK1_1307.ECOK1_0582,iECP_1309.ECP_0604,iECS88_1305.ECS88_0610,iECSF_1327.ECSF_0503,iETEC_1333.ETEC_0601,iEcDH1_1363.EcDH1_3056,iEcHS_1320.EcHS_A0620,iEcolC_1368.EcolC_3073,iJO1366.b0573,iLF82_1304.LF82_0388,iNRG857_1313.NRG857_02575,iSFV_1184.SFV_0506,iSF_1195.SF0474,iSFxv_1172.SFxv_0522,iS_1188.S0482,iUMN146_1321.UM146_14650,iUMNK88_1353.UMNK88_602,iUTI89_1310.UTI89_C0573,iY75_1357.Y75_RS02975,ic_1306.c0659 CusF_Ec DYD2_k127_2180215_52 1207076.ALAT01000110_gene1970 8.943e-07 55.0 COG5569@1|root,COG5569@2|Bacteria,1NGSZ@1224|Proteobacteria,1SGPW@1236|Gammaproteobacteria,1Z33F@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Copper binding periplasmic protein CusF cusF - - ko:K07810 ko02020,map02020 - - - ko00000,ko00001 2.A.6.1.4 - iAF1260.b0573,iBWG_1329.BWG_0444,iEC042_1314.EC042_0607,iECDH10B_1368.ECDH10B_0531,iECDH1ME8569_1439.ECDH1ME8569_0541,iETEC_1333.ETEC_0601,iEcDH1_1363.EcDH1_3056,iEcHS_1320.EcHS_A0620,iEcolC_1368.EcolC_3073,iJO1366.b0573,iUMNK88_1353.UMNK88_602,iY75_1357.Y75_RS02975 CusF_Ec DYD2_k127_2180215_27 483219.LILAB_34910 1.409e-56 207.0 COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,43C7V@68525|delta/epsilon subdivisions,2X7I7@28221|Deltaproteobacteria,2Z1WH@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth DYD2_k127_2180215_23 1236959.BAMT01000002_gene2258 3.928e-66 235.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,2KKTR@206350|Nitrosomonadales 206350|Nitrosomonadales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 DYD2_k127_2180215_11 748247.AZKH_3098 3.131e-129 426.0 COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,2KVPI@206389|Rhodocyclales 206389|Rhodocyclales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD DYD2_k127_2180215_42 580332.Slit_2175 1.263e-26 119.0 COG3678@1|root,COG3678@2|Bacteria,1N2D7@1224|Proteobacteria,2VU8P@28216|Betaproteobacteria 28216|Betaproteobacteria NPTU LTXXQ motif family protein - - - - - - - - - - - - LTXXQ DYD2_k127_2180215_31 395494.Galf_2722 9.285e-47 172.0 28WAT@1|root,2ZIB9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_2180215_43 365044.Pnap_1257 4.279e-25 113.0 2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2180215_45 472759.Nhal_1702 4.446e-17 91.0 COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,1TKC3@1236|Gammaproteobacteria,1X1RM@135613|Chromatiales 135613|Chromatiales S Short C-terminal domain - - - ko:K08982 - - - - ko00000 - - - SHOCT DYD2_k127_2180215_50 909663.KI867150_gene1675 1.35e-08 62.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MQRK@213462|Syntrophobacterales 28221|Deltaproteobacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - CLP_protease,NfeD,SDH_sah DYD2_k127_2180215_21 713586.KB900536_gene1396 5.273e-74 254.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1WWVC@135613|Chromatiales 135613|Chromatiales C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N DYD2_k127_2180215_26 1089552.KI911559_gene1278 1.114e-56 203.0 COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,2U6ZZ@28211|Alphaproteobacteria,2JU9D@204441|Rhodospirillales 204441|Rhodospirillales S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD2_k127_2180215_39 478741.JAFS01000001_gene1914 3.545e-31 127.0 COG0789@1|root,COG0789@2|Bacteria,46W3K@74201|Verrucomicrobia,37GZZ@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 DYD2_k127_2180215_1 1242864.D187_000364 3.204e-281 887.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales 28221|Deltaproteobacteria P copper-translocating P-type ATPase copF - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase,YHS DYD2_k127_2180215_18 754476.Q7A_1820 1.619e-85 289.0 28JNX@1|root,2Z9F0@2|Bacteria,1RGTM@1224|Proteobacteria,1SQJW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2180215_46 78245.Xaut_4886 1.927e-14 82.0 2DVDD@1|root,32UZ7@2|Bacteria,1NGRW@1224|Proteobacteria,2UC61@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2933) - - - - - - - - - - - - DUF2933 DYD2_k127_2180215_13 76114.ebA2182 2.352e-101 334.0 COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,2VJJ4@28216|Betaproteobacteria,2KVCR@206389|Rhodocyclales 206389|Rhodocyclales O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - ICMT,PEMT DYD2_k127_2180215_30 1366050.N234_32410 7.411e-48 181.0 COG2010@1|root,COG2010@2|Bacteria,1RGXM@1224|Proteobacteria,2VUPT@28216|Betaproteobacteria,1KDFB@119060|Burkholderiaceae 28216|Betaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD2_k127_2180215_40 269799.Gmet_1512 4.397e-30 131.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42PY0@68525|delta/epsilon subdivisions,2WJ2Y@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD2_k127_2180215_32 1095769.CAHF01000022_gene160 2.543e-45 166.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2VSDN@28216|Betaproteobacteria,474DS@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function, DUF - - - - - - - - - - - - DUF411 DYD2_k127_2180215_34 1123368.AUIS01000008_gene2225 1.718e-40 154.0 2ED0C@1|root,336XB@2|Bacteria,1ND2K@1224|Proteobacteria,1T8SB@1236|Gammaproteobacteria,2NDC7@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - DYD2_k127_2180215_38 1266925.JHVX01000002_gene952 2.791e-33 132.0 2E2UU@1|root,32XWR@2|Bacteria,1N192@1224|Proteobacteria,2VUA1@28216|Betaproteobacteria,3748T@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2180215_2 420662.Mpe_A3249 6.204e-207 655.0 COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,2VI2Z@28216|Betaproteobacteria,1KN33@119065|unclassified Burkholderiales 28216|Betaproteobacteria E SAF - - - - - - - - - - - - GFO_IDH_MocA,NAD_binding_3,SAF DYD2_k127_2180215_36 713586.KB900536_gene1636 1.625e-36 144.0 2BVK0@1|root,32QXS@2|Bacteria,1RKSK@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_2180215_25 316067.Geob_0726 2.564e-58 213.0 COG2067@1|root,COG2067@2|Bacteria,1N1F4@1224|Proteobacteria,42ZP2@68525|delta/epsilon subdivisions,2WUUM@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg DYD2_k127_2180215_20 365046.Rta_19360 1.62e-74 257.0 COG0723@1|root,COG0723@2|Bacteria,1MZ7A@1224|Proteobacteria,2VVI5@28216|Betaproteobacteria 28216|Betaproteobacteria C plastoquinol--plastocyanin reductase activity - - - - - - - - - - - - - DYD2_k127_2180215_0 1163617.SCD_n01944 0.0 1073.0 COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria 28216|Betaproteobacteria C CoA-binding domain protein yfiQ - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig DYD2_k127_2180215_28 1485544.JQKP01000002_gene1546 2.877e-50 187.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria,44VB0@713636|Nitrosomonadales 28216|Betaproteobacteria S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 DYD2_k127_2180215_5 580332.Slit_0423 1.927e-189 601.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,44V78@713636|Nitrosomonadales 28216|Betaproteobacteria H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM DYD2_k127_2180215_16 1121035.AUCH01000001_gene2081 9.529e-93 311.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,2KUDT@206389|Rhodocyclales 206389|Rhodocyclales K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases fnr - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding DYD2_k127_2180215_48 1288494.EBAPG3_12200 5.157e-11 68.0 COG2010@1|root,COG2010@2|Bacteria,1NF1C@1224|Proteobacteria,2VVP1@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome c - - - - - - - - - - - - - DYD2_k127_2180215_29 1123392.AQWL01000007_gene1010 8.764e-50 182.0 COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,1KT32@119069|Hydrogenophilales 119069|Hydrogenophilales O Hsp20/alpha crystallin family - - - - - - - - - - - - HSP20 DYD2_k127_2180215_44 1123393.KB891328_gene679 6.187e-20 91.0 2DN59@1|root,32VKR@2|Bacteria,1N627@1224|Proteobacteria,2WAKA@28216|Betaproteobacteria,1KT8N@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - DYD2_k127_2180215_33 159087.Daro_0718 8.542e-45 168.0 COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria,2KX1A@206389|Rhodocyclales 206389|Rhodocyclales S FixH family - - - ko:K09926 - - - - ko00000 - - - FixH DYD2_k127_2180215_4 983917.RGE_31890 3.299e-191 607.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1KIYJ@119065|unclassified Burkholderiales 28216|Betaproteobacteria C cytochrome C oxidase ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C DYD2_k127_2180215_47 1454004.AW11_03102 2.81e-11 72.0 COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2WFSD@28216|Betaproteobacteria,1KQZF@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB DYD2_k127_2180215_12 375286.mma_1634 9.353e-118 386.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4726F@75682|Oxalobacteraceae 28216|Betaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N DYD2_k127_2180215_49 1132855.KB913035_gene2298 4.566e-09 59.0 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ DYD2_k127_2180215_15 760117.JN27_04155 2.602e-97 321.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,472VR@75682|Oxalobacteraceae 28216|Betaproteobacteria C Cytochrome C oxidase, mono-heme subunit/FixO ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO DYD2_k127_2180215_3 305700.B447_07087 1.634e-199 626.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KVB2@206389|Rhodocyclales 206389|Rhodocyclales C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 DYD2_k127_21921_5 159087.Daro_0605 2.381e-123 402.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,2KUY4@206389|Rhodocyclales 206389|Rhodocyclales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 DYD2_k127_21921_10 1131553.JIBI01000011_gene721 6.707e-66 229.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,3732R@32003|Nitrosomonadales 28216|Betaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone DYD2_k127_21921_0 1163617.SCD_n00837 7.653e-196 617.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria 28216|Betaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT DYD2_k127_21921_11 640081.Dsui_1263 5.471e-57 205.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VRCB@28216|Betaproteobacteria,2KWFP@206389|Rhodocyclales 206389|Rhodocyclales Q TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ DYD2_k127_21921_3 1121033.AUCF01000001_gene1927 3.052e-175 563.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,2JQE2@204441|Rhodospirillales 204441|Rhodospirillales Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM DYD2_k127_21921_4 1121033.AUCF01000001_gene2015 1.422e-156 502.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,2JPP5@204441|Rhodospirillales 204441|Rhodospirillales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP DYD2_k127_21921_1 261292.Nit79A3_3265 7.324e-192 608.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,37276@32003|Nitrosomonadales 28216|Betaproteobacteria L modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD DYD2_k127_21921_12 580332.Slit_2379 1.23e-34 140.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,44VT9@713636|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF615) yjgA - - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 DYD2_k127_21921_6 1454004.AW11_02987 7.227e-94 312.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,1KQN4@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H Probable molybdopterin binding domain mogA - 2.7.7.75 ko:K03831 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth DYD2_k127_21921_9 29581.BW37_00373 6.107e-83 280.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,473QK@75682|Oxalobacteraceae 28216|Betaproteobacteria S Serine hydrolase (FSH1) estB - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 DYD2_k127_21921_8 640081.Dsui_1237 1.819e-87 308.0 2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria,2KVUH@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD2_k127_21921_2 323848.Nmul_A2758 1.312e-183 584.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2VKNE@28216|Betaproteobacteria,372VG@32003|Nitrosomonadales 28216|Betaproteobacteria S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 DYD2_k127_21921_7 1121035.AUCH01000007_gene452 3.09e-88 295.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,2KUX0@206389|Rhodocyclales 206389|Rhodocyclales C CoA-transferase family III - - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 DYD2_k127_2192642_15 876044.IMCC3088_857 5.018e-71 244.0 COG2304@1|root,COG2304@2|Bacteria,1QBPM@1224|Proteobacteria,1RQIU@1236|Gammaproteobacteria,1J4PZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Secreted protein, containing von Willebrand factor (VWF) type - - - - - - - - - - - - - DYD2_k127_2192642_27 1042377.AFPJ01000035_gene2636 6.843e-10 67.0 COG2304@1|root,COG2304@2|Bacteria,1QBPM@1224|Proteobacteria,1RQIU@1236|Gammaproteobacteria,466ZS@72275|Alteromonadaceae 1236|Gammaproteobacteria S Secreted protein, containing von Willebrand factor - - - - - - - - - - - - - DYD2_k127_2192642_13 1265313.HRUBRA_00929 1.792e-81 284.0 COG1196@1|root,COG1196@2|Bacteria,1R4BS@1224|Proteobacteria,1S13B@1236|Gammaproteobacteria,1J7UD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D von Willebrand factor (VWF) type A domain - - - - - - - - - - - - VWA_2 DYD2_k127_2192642_11 1415779.JOMH01000001_gene179 1.962e-87 300.0 COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Pfam MotA TolQ ExbB proton channel family - - - - - - - - - - - - MotA_ExbB DYD2_k127_2192642_3 1415778.JQMM01000001_gene1140 7.473e-143 486.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,1J55S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PEGA DYD2_k127_2192642_21 1121937.AUHJ01000017_gene3010 6.391e-49 193.0 COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,46864@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 DYD2_k127_2192642_12 1042377.AFPJ01000035_gene2629 2.55e-87 304.0 28MBM@1|root,2ZAQ2@2|Bacteria,1R5V6@1224|Proteobacteria,1S0K0@1236|Gammaproteobacteria,4662R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2192642_26 1415779.JOMH01000001_gene184 8.288e-12 76.0 2EDVS@1|root,337QX@2|Bacteria,1NEZW@1224|Proteobacteria,1SJBI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2192642_14 1000565.METUNv1_01912 2.295e-78 276.0 COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,2VTTP@28216|Betaproteobacteria,2KYW8@206389|Rhodocyclales 206389|Rhodocyclales M Protein of unknown function, DUF481 - - - - - - - - - - - - DUF481 DYD2_k127_2192642_24 1454004.AW11_03035 2.735e-19 94.0 COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,2VT65@28216|Betaproteobacteria 28216|Betaproteobacteria S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 DYD2_k127_2192642_10 1238182.C882_0582 2.031e-90 326.0 COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U26R@28211|Alphaproteobacteria,2JPQ3@204441|Rhodospirillales 204441|Rhodospirillales M AsmA family - - - ko:K07289,ko:K07290 - - - - ko00000 9.B.121 - - AsmA,AsmA_2 DYD2_k127_2192642_1 1095769.CAHF01000015_gene2767 2.871e-180 593.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria 28216|Betaproteobacteria M AsmA family - - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2 DYD2_k127_2192642_6 62928.azo3812 1.205e-116 386.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,2KUFV@206389|Rhodocyclales 206389|Rhodocyclales L A G-specific mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 DYD2_k127_2192642_17 582744.Msip34_2630 1.296e-59 212.0 2AQI0@1|root,31FQP@2|Bacteria,1RI31@1224|Proteobacteria,2VUDX@28216|Betaproteobacteria,2KMU0@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - DYD2_k127_2192642_9 395495.Lcho_0061 2.694e-105 356.0 COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,2VX2X@28216|Betaproteobacteria 28216|Betaproteobacteria O Thioredoxin-like - - - ko:K07152 - - - - ko00000,ko03029 - - - Thioredoxin_2 DYD2_k127_2192642_19 1123261.AXDW01000014_gene3343 3.465e-55 201.0 COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,1S54H@1236|Gammaproteobacteria,1X61Q@135614|Xanthomonadales 135614|Xanthomonadales S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg DYD2_k127_2192642_7 1163617.SCD_n00553 3.507e-112 369.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria 28216|Betaproteobacteria S Displays ATPase and GTPase activities yhbJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 DYD2_k127_2192642_8 1288494.EBAPG3_7390 3.3e-106 355.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,372NZ@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N DYD2_k127_2192642_16 335283.Neut_2305 6.222e-69 237.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,372H5@32003|Nitrosomonadales 28216|Betaproteobacteria GT PTS IIA-like nitrogen-regulatory protein PtsN ptsN - - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 DYD2_k127_2192642_23 1163617.SCD_n00556 1.298e-38 146.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria 28216|Betaproteobacteria J sigma 54 modulation protein ribosomal protein S30EA raiA - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE DYD2_k127_2192642_2 1288494.EBAPG3_7410 3.628e-178 571.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,371WJ@32003|Nitrosomonadales 28216|Betaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD DYD2_k127_2192642_5 323848.Nmul_A0085 2.319e-118 386.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,372DG@32003|Nitrosomonadales 28216|Betaproteobacteria S Branched-chain amino acid ATP-binding cassette transporter lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C DYD2_k127_2192642_20 323848.Nmul_A0086 5.651e-53 194.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,3727R@32003|Nitrosomonadales 28216|Betaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane lptA - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA DYD2_k127_2192642_22 1163617.SCD_n00560 2.49e-44 171.0 COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria 28216|Betaproteobacteria S protein conserved in bacteria lptC - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC DYD2_k127_2192642_18 748280.NH8B_3325 3.233e-56 201.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,2KR4K@206351|Neisseriales 206351|Neisseriales S 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family kdsC - 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase,Hydrolase_3 DYD2_k127_2192642_4 1434929.X946_2123 6.348e-130 422.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,1K0GY@119060|Burkholderiaceae 28216|Betaproteobacteria M Belongs to the SIS family. GutQ KpsF subfamily kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS DYD2_k127_2192642_0 1131553.JIBI01000010_gene1362 4.061e-249 787.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,374MC@32003|Nitrosomonadales 28216|Betaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefB - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C,TrkA_N DYD2_k127_2192642_25 1469245.JFBG01000027_gene1443 5.943e-12 71.0 COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,1SF74@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl DYD2_k127_2209152_29 1163617.SCD_n00281 6.438e-70 257.0 2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2209152_37 1163617.SCD_n00278 3.433e-45 166.0 COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria 28216|Betaproteobacteria S membrane yqaA - - - - - - - - - - - SNARE_assoc DYD2_k127_2209152_8 1068980.ARVW01000001_gene1899 5.386e-153 491.0 COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria,4E10Q@85010|Pseudonocardiales 201174|Actinobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.156,4.2.1.42 ko:K20023 ko00053,map00053 - R05608 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N DYD2_k127_2209152_13 639283.Snov_0512 9.436e-125 412.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,3EY3I@335928|Xanthobacteraceae 28211|Alphaproteobacteria C PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD2_k127_2209152_39 1122236.KB905141_gene1334 1.408e-33 143.0 COG0438@1|root,COG0457@1|root,COG0859@1|root,COG4627@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,COG4627@2|Bacteria,1RBR3@1224|Proteobacteria,2VSKQ@28216|Betaproteobacteria,2KP39@206350|Nitrosomonadales 206350|Nitrosomonadales M Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 DYD2_k127_2209152_28 1430440.MGMSRv2_3490 2.429e-70 242.0 COG2227@1|root,COG2227@2|Bacteria,1QYVF@1224|Proteobacteria,2TZ70@28211|Alphaproteobacteria 28211|Alphaproteobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - - DYD2_k127_2209152_24 1453500.AT05_01460 1.172e-79 271.0 COG0223@1|root,COG0223@2|Bacteria 2|Bacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - GO:0003674,GO:0003824,GO:0004479,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044419,GO:0046483,GO:0046983,GO:0051704,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.2,2.1.2.9 ko:K00604,ko:K11175 ko00230,ko00670,ko00970,ko01100,ko01110,ko01130,map00230,map00670,map00970,map01100,map01110,map01130 M00048 R03940,R04325,R04326 RC00026,RC00165,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N DYD2_k127_2209152_5 269799.Gmet_2332 6.577e-168 536.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42N6P@68525|delta/epsilon subdivisions,2WJVY@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Belongs to the DegT DnrJ EryC1 family - - 2.6.1.33 ko:K20429 - - R02773 RC00006,RC00781 ko00000,ko01000 - - - DegT_DnrJ_EryC1 DYD2_k127_2209152_27 870187.Thini_3578 4.804e-72 246.0 COG3012@1|root,COG3012@2|Bacteria,1N4HZ@1224|Proteobacteria,1SFB1@1236|Gammaproteobacteria,462H1@72273|Thiotrichales 72273|Thiotrichales S SEC-C Motif Domain Protein - - - - - - - - - - - - - DYD2_k127_2209152_35 1175306.GWL_14980 7.952e-54 212.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,475KY@75682|Oxalobacteraceae 28216|Betaproteobacteria M Tetratricopeptide repeat - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_16,TPR_2,TPR_8 DYD2_k127_2209152_41 76114.p2A117 1.24e-14 86.0 COG3203@1|root,COG3203@2|Bacteria,1MWK2@1224|Proteobacteria,2VMGP@28216|Betaproteobacteria,2KZN8@206389|Rhodocyclales 206389|Rhodocyclales M Gram-negative porin - - - - - - - - - - - - Porin_4 DYD2_k127_2209152_12 265072.Mfla_1389 2.325e-131 450.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,2KKW3@206350|Nitrosomonadales 206350|Nitrosomonadales O Glycosyl transferase family 41 - - - - - - - - - - - - Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 DYD2_k127_2209152_36 1163617.SCD_n00186 6.077e-50 186.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VSEK@28216|Betaproteobacteria 28216|Betaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE8 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_2209152_19 1163617.SCD_n00185 9.812e-97 323.0 COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria 28216|Betaproteobacteria K transmembrane transcriptional regulator (Anti-sigma factor) prtR - - - - - - - - - - - zf-HC2 DYD2_k127_2209152_4 1288494.EBAPG3_3030 1.697e-173 556.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,371R9@32003|Nitrosomonadales 28216|Betaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC DYD2_k127_2209152_21 582744.Msip34_2129 5.08e-90 307.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,2KKR3@206350|Nitrosomonadales 206350|Nitrosomonadales I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD2_k127_2209152_25 1163617.SCD_n02567 4.992e-78 265.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria 28216|Betaproteobacteria E D,D-heptose 1,7-bisphosphate phosphatase gmhB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase,Hydrolase_like,PNK3P DYD2_k127_2209152_2 243365.CV_1656 4.331e-207 668.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,2KPTM@206351|Neisseriales 206351|Neisseriales J glycyl-tRNA synthetase beta glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f DYD2_k127_2209152_7 312153.Pnuc_1863 2.956e-159 508.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,1K1XK@119060|Burkholderiaceae 28216|Betaproteobacteria J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e DYD2_k127_2209152_6 323848.Nmul_A0552 6.627e-166 539.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,37222@32003|Nitrosomonadales 28216|Betaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase DYD2_k127_2209152_14 1266925.JHVX01000011_gene1475 2.639e-123 400.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,372B3@32003|Nitrosomonadales 28216|Betaproteobacteria P Transporter associated domain corC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC DYD2_k127_2209152_38 1163617.SCD_n02589 9.351e-44 165.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria 28216|Betaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 DYD2_k127_2209152_11 522306.CAP2UW1_1248 1.425e-142 463.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria,1KPUA@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria T PhoH-like phosphate starvation-inducible protein ybeZ - - ko:K06217 - - - - ko00000 - - - PhoH DYD2_k127_2209152_1 1123393.KB891316_gene2104 2.138e-212 669.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,1KRFR@119069|Hydrogenophilales 119069|Hydrogenophilales J Uncharacterized protein family UPF0004 - - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 DYD2_k127_2209152_15 323848.Nmul_A2444 3.174e-121 400.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,372D2@32003|Nitrosomonadales 28216|Betaproteobacteria C TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 ubiF - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,FAD_binding_3,SE DYD2_k127_2209152_34 748247.AZKH_0662 1.058e-56 206.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,2KW1Z@206389|Rhodocyclales 206389|Rhodocyclales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 DYD2_k127_2209152_10 1163617.SCD_n02537 3.729e-147 477.0 COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria 28216|Betaproteobacteria M membrane-bound lytic murein transglycosylase mltA - - ko:K08304 - - - - ko00000,ko01000,ko01011 - GH102 - 3D,MltA DYD2_k127_2209152_33 1163617.SCD_n02536 3.809e-57 201.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria 28216|Betaproteobacteria P PFAM ApaG domain protein apaG - - ko:K06195 - - - - ko00000 - - - DUF525 DYD2_k127_2209152_16 1288494.EBAPG3_26480 1.809e-109 357.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,371Y4@32003|Nitrosomonadales 28216|Betaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim DYD2_k127_2209152_23 1266925.JHVX01000010_gene1339 7.851e-81 274.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,371Y5@32003|Nitrosomonadales 28216|Betaproteobacteria G HAD-superfamily hydrolase, subfamily IA, variant 3 gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 DYD2_k127_2209152_0 62928.azo3325 5.897e-227 711.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,2KVHH@206389|Rhodocyclales 206389|Rhodocyclales E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind DYD2_k127_2209152_3 290317.Cpha266_1841 7.334e-204 666.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1FDGV@1090|Chlorobi 1090|Chlorobi H SMART Tetratricopeptide domain protein - - - - - - - - - - - - Glyco_transf_41,TPR_1,TPR_8 DYD2_k127_2209152_18 1163617.SCD_n02532 2.637e-98 325.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria 28216|Betaproteobacteria EH Glutamine amidotransferase of anthranilate synthase trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase DYD2_k127_2209152_9 1454004.AW11_01954 7.264e-148 479.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,1KPU3@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 DYD2_k127_2209152_20 365046.Rta_35790 2.967e-94 321.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,4ABED@80864|Comamonadaceae 28216|Betaproteobacteria E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS DYD2_k127_2209152_22 323848.Nmul_A0341 1.312e-83 283.0 COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,371ZQ@32003|Nitrosomonadales 28216|Betaproteobacteria H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 DYD2_k127_2209152_40 243231.GSU3023 9.607e-31 136.0 COG0297@1|root,COG0457@1|root,COG1216@1|root,COG0297@2|Bacteria,COG0457@2|Bacteria,COG1216@2|Bacteria,1QXPI@1224|Proteobacteria,43C5D@68525|delta/epsilon subdivisions 1224|Proteobacteria G Glycosyltransferase like family 2 - - - ko:K07011,ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glycos_transf_2 DYD2_k127_2209152_31 580332.Slit_2473 2.058e-64 224.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,44VTK@713636|Nitrosomonadales 28216|Betaproteobacteria O OsmC-like protein yhfA - - ko:K07397 - - - - ko00000 - - - OsmC DYD2_k127_2209152_30 580332.Slit_2472 9.424e-66 232.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,44W6B@713636|Nitrosomonadales 28216|Betaproteobacteria S DUF218 domain - - - - - - - - - - - - DUF218 DYD2_k127_2209152_26 323848.Nmul_A0561 4.565e-73 248.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,37319@32003|Nitrosomonadales 28216|Betaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 DYD2_k127_2209152_32 261292.Nit79A3_0690 1.615e-59 216.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,3730F@32003|Nitrosomonadales 28216|Betaproteobacteria J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 DYD2_k127_225323_9 1215114.BBIU01000013_gene1848 3.578e-39 155.0 COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE DYD2_k127_225323_1 522306.CAP2UW1_1517 2.043e-294 942.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria,1KPWD@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase DYD2_k127_225323_8 1297742.A176_06772 1.343e-52 198.0 COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,434AF@68525|delta/epsilon subdivisions,2X23S@28221|Deltaproteobacteria,2YVSR@29|Myxococcales 28221|Deltaproteobacteria G Belongs to the phosphoglycerate mutase family - - 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 DYD2_k127_225323_7 1288494.EBAPG3_11070 3.283e-55 199.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2VU6X@28216|Betaproteobacteria 28216|Betaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 DYD2_k127_225323_3 1288494.EBAPG3_11060 1e-104 351.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,371PB@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep DYD2_k127_225323_4 556268.OFAG_01428 4.466e-96 318.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria,473B4@75682|Oxalobacteraceae 28216|Betaproteobacteria S Phosphatidylethanolamine-binding protein bbsI - - ko:K06910 - - - - ko00000 - - - PBP DYD2_k127_225323_0 1266925.JHVX01000001_gene2612 0.0 1601.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,3727F@32003|Nitrosomonadales 28216|Betaproteobacteria L Helicase associated domain (HA2) Add an annotation hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind DYD2_k127_225323_11 279714.FuraDRAFT_2043 0.000273 52.0 2FHC1@1|root,3496B@2|Bacteria,1P3SU@1224|Proteobacteria,2W4GA@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_225323_6 913325.N799_05785 4.92e-63 223.0 COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - Rhomboid DYD2_k127_225323_5 1532557.JL37_26170 1.329e-78 270.0 COG0684@1|root,COG0684@2|Bacteria,1PIP4@1224|Proteobacteria,2WB5S@28216|Betaproteobacteria,3T7UZ@506|Alcaligenaceae 28216|Betaproteobacteria H Aldolase/RraA - - - - - - - - - - - - RraA-like DYD2_k127_225323_2 1207063.P24_01946 2.185e-155 495.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JUXN@204441|Rhodospirillales 204441|Rhodospirillales EG Belongs to the IlvD Edd family - - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD2_k127_2258044_6 290315.Clim_1318 2.228e-64 225.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - - - - - - - - - - - FHA,Trypsin,Trypsin_2 DYD2_k127_2258044_5 388051.AUFE01000048_gene2421 4.487e-77 269.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM0F@28216|Betaproteobacteria 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_2258044_13 1082931.KKY_1225 2.603e-36 147.0 COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2TVGA@28211|Alphaproteobacteria,3N7C4@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria H glutathione S-transferase bphK - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_2,GST_N_3 DYD2_k127_2258044_1 338963.Pcar_0565 5.165e-133 442.0 COG5373@1|root,COG5373@2|Bacteria,1QFJD@1224|Proteobacteria,43499@68525|delta/epsilon subdivisions,2X2KI@28221|Deltaproteobacteria,43VWU@69541|Desulfuromonadales 28221|Deltaproteobacteria S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 DYD2_k127_2258044_14 1156937.MFUM_970053 5.98e-25 108.0 COG2146@1|root,COG2146@2|Bacteria,46WQG@74201|Verrucomicrobia,37HBF@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia P Rieske-like [2Fe-2S] domain - - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske DYD2_k127_2258044_2 234267.Acid_4061 2.474e-129 422.0 COG0189@1|root,COG0189@2|Bacteria 2|Bacteria HJ Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - CPSase_L_D2,Dala_Dala_lig_C,RimK DYD2_k127_2258044_7 1274524.BSONL12_04873 5.267e-64 222.0 COG0346@1|root,COG0346@2|Bacteria,1V36W@1239|Firmicutes,4IQ29@91061|Bacilli,1ZRGR@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K07032 - - - - ko00000 - - - Glyoxalase DYD2_k127_2258044_0 196490.AUEZ01000136_gene5052 8.536e-184 589.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TRHJ@28211|Alphaproteobacteria,3JW9N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 DYD2_k127_2258044_16 1002340.AFCF01000004_gene2992 1.389e-10 71.0 COG0784@1|root,COG4251@1|root,COG0784@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,2UP7T@28211|Alphaproteobacteria,34G51@302485|Phaeobacter 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg DYD2_k127_2258044_9 1439940.BAY1663_03015 9.101e-60 216.0 COG2197@1|root,COG2197@2|Bacteria,1RGN8@1224|Proteobacteria 1224|Proteobacteria K Response regulator, receiver - - - - - - - - - - - - GerE,Response_reg DYD2_k127_2258044_3 1298867.AUES01000041_gene897 5.749e-127 413.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TYVX@28211|Alphaproteobacteria,3JWZ3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 DYD2_k127_2258044_8 1219031.BBJR01000024_gene403 1.477e-62 230.0 COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,2VIUY@28216|Betaproteobacteria,4ABAI@80864|Comamonadaceae 28216|Betaproteobacteria EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1,Sugar_tr DYD2_k127_2258044_4 1116472.MGMO_121c00100 2.816e-115 388.0 COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,1RNQP@1236|Gammaproteobacteria,1XFX9@135618|Methylococcales 135618|Methylococcales C Flavin-binding monooxygenase-like - - - ko:K07222 - - - - ko00000 - - - Pyr_redox_3 DYD2_k127_2258044_12 743299.Acife_3160 1.067e-36 149.0 COG3239@1|root,COG3239@2|Bacteria 2|Bacteria I unsaturated fatty acid biosynthetic process desA3 GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - iJN678.desD_des6_ FA_desaturase DYD2_k127_2258044_11 46234.ANA_C10535 3.607e-51 189.0 COG0860@1|root,COG0860@2|Bacteria,1G008@1117|Cyanobacteria,1HKI1@1161|Nostocales 1117|Cyanobacteria M Localisation of periplasmic protein complexes - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 DYD2_k127_2258044_10 1121861.KB899915_gene1849 4.163e-56 207.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TUWV@28211|Alphaproteobacteria,2JQWC@204441|Rhodospirillales 204441|Rhodospirillales E Pyridoxal-phosphate dependent enzyme - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_2264628_0 1469245.JFBG01000062_gene2271 3.138e-200 639.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM DYD2_k127_2264628_5 1123242.JH636435_gene2868 2.053e-49 184.0 COG1247@1|root,COG1247@2|Bacteria,2J0C9@203682|Planctomycetes 203682|Planctomycetes M Acetyltransferase (GNAT) domain - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 DYD2_k127_2264628_6 1205680.CAKO01000002_gene2378 2.582e-39 158.0 COG2175@1|root,COG2175@2|Bacteria,1MVI6@1224|Proteobacteria,2TVHF@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - ko:K06912 ko00361,ko01120,ko01220,map00361,map01120,map01220 - R05419,R05493 RC01371,RC01372 ko00000,ko00001,ko01000 - - - TauD DYD2_k127_2264628_2 1395571.TMS3_0118435 1.92e-82 280.0 28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,1S4WY@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2264628_4 1133850.SHJG_0832 9.417e-69 249.0 2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria 201174|Actinobacteria S PFAM Nitrile hydratase alpha scnC - 3.5.5.8,4.2.1.84 ko:K01721,ko:K20762 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R02828,R04020,R05379,R05596,R07780,R07854 RC00483,RC00792,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_alpha DYD2_k127_2264628_7 1380394.JADL01000002_gene1249 5.059e-36 140.0 2DBV6@1|root,32TY6@2|Bacteria,1N0TC@1224|Proteobacteria,2UCAJ@28211|Alphaproteobacteria,2JXVR@204441|Rhodospirillales 204441|Rhodospirillales S Nitrile hydratase beta subunit - - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta DYD2_k127_2264628_8 1123360.thalar_00810 9.139e-15 81.0 2DWFS@1|root,32V1J@2|Bacteria,1MZ9A@1224|Proteobacteria,2UDME@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Nitrile hydratase beta subunit - - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta DYD2_k127_2264628_3 358220.C380_21385 4.859e-77 266.0 COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VM00@28216|Betaproteobacteria,4ABHF@80864|Comamonadaceae 28216|Betaproteobacteria S Ankyrin repeats (3 copies) - - - ko:K06867 - - - - ko00000 - - - Ank_2,Ank_4 DYD2_k127_2264628_1 1120999.JONM01000002_gene950 4.169e-90 305.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VIVP@28216|Betaproteobacteria,2KTRA@206351|Neisseriales 206351|Neisseriales CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_2264628_9 1123252.ATZF01000022_gene3005 0.0005154 48.0 COG2140@1|root,COG2140@2|Bacteria,1TPC2@1239|Firmicutes,4HA6V@91061|Bacilli,27CQK@186824|Thermoactinomycetaceae 91061|Bacilli G Cupin oxdD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0033609,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046564,GO:0071704 4.1.1.2 ko:K01569 ko00630,ko01100,map00630,map01100 - R00522 RC00321 ko00000,ko00001,ko01000 - - iYO844.BSU18670 Cupin_1 DYD2_k127_2284230_9 1000565.METUNv1_04052 8.202e-130 418.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM DYD2_k127_2284230_12 76114.ebA2944 4.867e-121 396.0 COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,2KV23@206389|Rhodocyclales 206389|Rhodocyclales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ DYD2_k127_2284230_18 748247.AZKH_0068 3.817e-75 259.0 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,2KW8P@206389|Rhodocyclales 206389|Rhodocyclales H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD2_k127_2284230_17 323848.Nmul_A1872 3.256e-83 292.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,37224@32003|Nitrosomonadales 28216|Betaproteobacteria F Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase,HTH_6,SIS DYD2_k127_2284230_5 1123368.AUIS01000019_gene1219 3.097e-190 623.0 COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 DYD2_k127_2284230_16 323848.Nmul_A1873 2.185e-89 301.0 COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,372KR@32003|Nitrosomonadales 28216|Betaproteobacteria S Belongs to the MtfA family mtfA - - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 DYD2_k127_2284230_6 582744.Msip34_1733 4.114e-143 467.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,2KM0V@206350|Nitrosomonadales 206350|Nitrosomonadales S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC DYD2_k127_2284230_1 640081.Dsui_2415 5.47e-247 788.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,2KU7T@206389|Rhodocyclales 206389|Rhodocyclales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX DYD2_k127_2284230_14 323848.Nmul_A1972 9.161e-91 304.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,3722E@32003|Nitrosomonadales 28216|Betaproteobacteria Q ABC transporter lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_2284230_20 399739.Pmen_2558 9.047e-64 229.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1YEZU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E GDSL-like Lipase/Acylhydrolase tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Lipase_GDSL_2 DYD2_k127_2284230_7 1163617.SCD_n01580 5.294e-143 460.0 COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria 28216|Betaproteobacteria H Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 DYD2_k127_2284230_10 1163617.SCD_n01581 3.387e-129 422.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA selU - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese DYD2_k127_2284230_15 1163617.SCD_n01755 5.25e-90 304.0 COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,2VKEP@28216|Betaproteobacteria 28216|Betaproteobacteria G polysaccharide deacetylase arnD - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_2284230_19 1288494.EBAPG3_25720 2.66e-72 246.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,3737P@32003|Nitrosomonadales 28216|Betaproteobacteria O PFAM Alkyl hydroperoxide reductase bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD2_k127_2284230_2 1288494.EBAPG3_25730 1.803e-243 758.0 COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,372PF@32003|Nitrosomonadales 28216|Betaproteobacteria T Large family of predicted nucleotide-binding domains phoH - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH DYD2_k127_2284230_4 323848.Nmul_A1947 3.001e-199 631.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,372T4@32003|Nitrosomonadales 28216|Betaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C DYD2_k127_2284230_23 1288494.EBAPG3_25750 3.569e-57 202.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,37399@32003|Nitrosomonadales 28216|Betaproteobacteria J Binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N DYD2_k127_2284230_24 323848.Nmul_A1949 9.568e-33 130.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,373BA@32003|Nitrosomonadales 28216|Betaproteobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 DYD2_k127_2284230_25 1163617.SCD_n01791 1.368e-18 95.0 COG2965@1|root,COG2965@2|Bacteria,1N98W@1224|Proteobacteria,2VVZ4@28216|Betaproteobacteria 28216|Betaproteobacteria L Binds single-stranded DNA at the primosome assembly site (PAS) priB - - ko:K02686 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SSB DYD2_k127_2284230_21 1000565.METUNv1_00770 5.559e-62 215.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,2KWGN@206389|Rhodocyclales 206389|Rhodocyclales J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 DYD2_k127_2284230_8 1349767.GJA_3586 8.156e-139 473.0 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria 28216|Betaproteobacteria U TIGRFAM filamentous haemagglutinin family outer membrane protein - - - - - - - - - - - - ESPR,Glug,Haemagg_act DYD2_k127_2284230_11 1198452.Jab_2c21380 1.049e-127 426.0 COG2831@1|root,COG2831@2|Bacteria,1PRBP@1224|Proteobacteria,2VHDS@28216|Betaproteobacteria,475Q6@75682|Oxalobacteraceae 28216|Betaproteobacteria U Hemolysin activation secretion protein - - - - - - - - - - - - POTRA,POTRA_2,ShlB DYD2_k127_2284230_13 580332.Slit_1428 8.155e-99 331.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,44VAT@713636|Nitrosomonadales 28216|Betaproteobacteria J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind DYD2_k127_2284230_0 1288494.EBAPG3_25810 5.801e-311 967.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,371V5@32003|Nitrosomonadales 28216|Betaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 DYD2_k127_2284230_27 925409.KI911562_gene1687 4.269e-05 48.0 COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IPXM@117747|Sphingobacteriia 976|Bacteroidetes L PFAM Resolvase, N-terminal - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom DYD2_k127_2284230_3 1266925.JHVX01000003_gene685 1.617e-227 709.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,372QC@32003|Nitrosomonadales 28216|Betaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt DYD2_k127_2284230_26 640081.Dsui_3133 7.56e-17 82.0 COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,2KX7Z@206389|Rhodocyclales 206389|Rhodocyclales S protein conserved in bacteria - - - ko:K09937 - - - - ko00000 - - - DUF2065 DYD2_k127_2284230_22 1266925.JHVX01000003_gene682 7.145e-58 203.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,371T3@32003|Nitrosomonadales 28216|Betaproteobacteria O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 DYD2_k127_2299762_3 323848.Nmul_A0045 5.064e-143 460.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,372NK@32003|Nitrosomonadales 28216|Betaproteobacteria H Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans DYD2_k127_2299762_11 1123401.JHYQ01000001_gene1788 2.85e-54 201.0 COG1266@1|root,COG1266@2|Bacteria,1QSFU@1224|Proteobacteria 1224|Proteobacteria S CAAX amino Terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi DYD2_k127_2299762_14 1318628.MARLIPOL_16289 4.034e-18 91.0 2F7U0@1|root,34084@2|Bacteria,1NZJ4@1224|Proteobacteria 1318628.MARLIPOL_16289|- - - - - - - - - - - - - - - - DYD2_k127_2299762_12 1318628.MARLIPOL_02715 4.135e-52 191.0 2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,1SUQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2299762_2 272560.BPSL2979 1.454e-200 634.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,1K14Y@119060|Burkholderiaceae 28216|Betaproteobacteria M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD2_k127_2299762_4 1121033.AUCF01000012_gene953 7.104e-134 447.0 COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2TS1E@28211|Alphaproteobacteria,2JQ0T@204441|Rhodospirillales 204441|Rhodospirillales J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase DYD2_k127_2299762_9 1163617.SCD_n00215 1.526e-62 221.0 COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria 28216|Betaproteobacteria S esterase yqiA - - ko:K07000 - - - - ko00000 - - - UPF0227 DYD2_k127_2299762_1 1266925.JHVX01000003_gene589 4.936e-222 704.0 COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,3721E@32003|Nitrosomonadales 28216|Betaproteobacteria K ribonuclease II rnb - 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - RNB DYD2_k127_2299762_6 1163617.SCD_n00213 1.058e-81 283.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria 28216|Betaproteobacteria M TIGRFAM TonB family protein - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_2,TonB_C DYD2_k127_2299762_5 748247.AZKH_3828 1.957e-91 309.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,2KUFF@206389|Rhodocyclales 206389|Rhodocyclales E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N DYD2_k127_2299762_7 1122951.ATUE01000005_gene2171 3.994e-81 280.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,3NIFT@468|Moraxellaceae 1236|Gammaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly DYD2_k127_2299762_10 1123368.AUIS01000024_gene953 1.471e-60 215.0 COG2890@1|root,COG2890@2|Bacteria,1MY5I@1224|Proteobacteria,1T26C@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase (PrmA) - - - - - - - - - - - - Methyltransf_31,PrmA DYD2_k127_2299762_8 1123277.KB893179_gene3151 7.469e-74 250.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47XN3@768503|Cytophagia 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 DYD2_k127_2299762_0 639283.Snov_1976 1.576e-241 766.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,3EYE0@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MA20_17495 - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD2_k127_2299762_13 288000.BBta_2764 7.773e-37 152.0 COG2010@1|root,COG2010@2|Bacteria,1RIV2@1224|Proteobacteria,2U9C5@28211|Alphaproteobacteria,3JZ5J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c - - - ko:K17223 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Cytochrom_C DYD2_k127_2316609_13 757424.Hsero_2187 1.502e-05 48.0 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,474EF@75682|Oxalobacteraceae 28216|Betaproteobacteria M Belongs to the skp family ompH - - ko:K06142 - - - - ko00000 - - - OmpH DYD2_k127_2316609_1 1095769.CAHF01000009_gene1397 8.97e-157 500.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,4730X@75682|Oxalobacteraceae 28216|Betaproteobacteria F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA - - - - - - - - - - - APH DYD2_k127_2316609_6 518766.Rmar_2620 7.898e-79 279.0 COG1231@1|root,COG1231@2|Bacteria,4NP86@976|Bacteroidetes 976|Bacteroidetes E PFAM amine oxidase - - - - - - - - - - - - Amino_oxidase DYD2_k127_2316609_2 1144342.PMI40_00660 5.46e-110 366.0 COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2VH3I@28216|Betaproteobacteria,4743X@75682|Oxalobacteraceae 28216|Betaproteobacteria S Esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin DYD2_k127_2316609_3 648757.Rvan_3586 1.374e-102 339.0 COG4887@1|root,COG4887@2|Bacteria,1RKM1@1224|Proteobacteria,2U481@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1847) - - - - - - - - - - - - DUF1847 DYD2_k127_2316609_4 94624.Bpet3459 2.309e-81 282.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T21B@506|Alcaligenaceae 28216|Betaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_2316609_10 1265502.KB905955_gene462 4.852e-21 97.0 2BZ72@1|root,32YQ2@2|Bacteria,1NC8P@1224|Proteobacteria,2VWE4@28216|Betaproteobacteria,4AG3I@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2316609_5 257310.BB0925 2.439e-81 280.0 COG2175@1|root,COG2175@2|Bacteria,1MVI6@1224|Proteobacteria,2W1MQ@28216|Betaproteobacteria,3T5NW@506|Alcaligenaceae 28216|Betaproteobacteria Q Taurine catabolism dioxygenase TauD, TfdA family - - 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 - R05320 RC01331 ko00000,ko00001,ko01000 - - - TauD DYD2_k127_2316609_11 395493.BegalDRAFT_1156 6.656e-14 78.0 2EEHS@1|root,338BM@2|Bacteria,1NHGX@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_2316609_7 1380394.JADL01000011_gene3814 1.044e-55 205.0 COG2318@1|root,COG2318@2|Bacteria,1RHRP@1224|Proteobacteria,2UEZW@28211|Alphaproteobacteria,2JXIY@204441|Rhodospirillales 204441|Rhodospirillales S DinB family - - - - - - - - - - - - DinB DYD2_k127_2316609_12 1040986.ATYO01000008_gene2689 6.679e-09 63.0 COG0662@1|root,COG0662@2|Bacteria,1RHN1@1224|Proteobacteria,2U8E9@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_2316609_0 926560.KE387027_gene713 1.25e-227 727.0 COG2303@1|root,COG2303@2|Bacteria,1WMTM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N DYD2_k127_2316609_8 926560.KE387027_gene712 2.629e-42 160.0 2DB8V@1|root,2Z7SX@2|Bacteria 2|Bacteria S Gluconate 2-dehydrogenase - - 1.1.99.3 ko:K06152 ko00030,ko01100,ko01120,map00030,map01100,map01120 - R01741 RC00084 ko00000,ko00001,ko01000 - - - Gluconate_2-dh3,TAT_signal DYD2_k127_2331469_0 1229205.BUPH_06788 7.111e-123 404.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1MVN5@1224|Proteobacteria,2VII1@28216|Betaproteobacteria,1K2HH@119060|Burkholderiaceae 28216|Betaproteobacteria L similarity to GP 17427840 - - - - - - - - - - - - HTH_21,rve_3 DYD2_k127_2331469_11 1033802.SSPSH_003749 2.221e-18 88.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1SA6S@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1 DYD2_k127_2331469_2 748247.AZKH_1349 1.509e-84 289.0 COG1397@1|root,COG1397@2|Bacteria,1PRWK@1224|Proteobacteria,2WA1G@28216|Betaproteobacteria,2KZF1@206389|Rhodocyclales 206389|Rhodocyclales O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH DYD2_k127_2331469_8 1123368.AUIS01000003_gene1656 2.137e-39 152.0 COG2337@1|root,COG2337@2|Bacteria,1MZAV@1224|Proteobacteria,1S7ZM@1236|Gammaproteobacteria,2NDZG@225057|Acidithiobacillales 225057|Acidithiobacillales T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin DYD2_k127_2331469_14 426114.THI_2831 3.104e-08 64.0 2C78Q@1|root,331C6@2|Bacteria,1N873@1224|Proteobacteria,2VY62@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3018) - - - - - - - - - - - - DUF3018 DYD2_k127_2331469_5 292415.Tbd_2635 7.392e-48 176.0 COG0494@1|root,COG0494@2|Bacteria,1MYSK@1224|Proteobacteria,2W3WC@28216|Betaproteobacteria 28216|Betaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX DYD2_k127_2331469_4 713586.KB900536_gene1232 1.518e-58 209.0 2ECCV@1|root,336B4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2204 DYD2_k127_2331469_1 318996.AXAZ01000043_gene2046 7.759e-102 349.0 COG1222@1|root,COG2127@1|root,COG1222@2|Bacteria,COG2127@2|Bacteria,1R4U1@1224|Proteobacteria,2TRGA@28211|Alphaproteobacteria,3JQS6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O ATP-dependent Clp protease adaptor protein ClpS - - - - - - - - - - - - AAA,ClpS DYD2_k127_2331469_6 710686.Mycsm_01181 9.638e-41 154.0 2FBTW@1|root,321XM@2|Bacteria,2H64G@201174|Actinobacteria,23DVG@1762|Mycobacteriaceae 201174|Actinobacteria S Antitoxin Phd_YefM, type II toxin-antitoxin system - - - - - - - - - - - - PhdYeFM_antitox DYD2_k127_2331469_3 710686.Mycsm_01180 3.481e-81 276.0 COG4185@1|root,COG4185@2|Bacteria,2GX9Z@201174|Actinobacteria,23CAG@1762|Mycobacteriaceae 201174|Actinobacteria S Zeta toxin - - - - - - - - - - - - Zeta_toxin DYD2_k127_2331469_7 637390.AFOH01000025_gene1036 6.072e-40 154.0 COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria 1236|Gammaproteobacteria M ORF6N domain - - - - - - - - - - - - ORF6N DYD2_k127_2331469_10 1122135.KB893170_gene2663 3.579e-24 105.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD2_k127_2331469_9 1396141.BATP01000001_gene5394 6.776e-32 130.0 2DQ16@1|root,334AZ@2|Bacteria,46XJ5@74201|Verrucomicrobia,2IW1X@203494|Verrucomicrobiae 203494|Verrucomicrobiae S SpoIIAA-like - - - - - - - - - - - - SpoIIAA-like DYD2_k127_2331469_12 1121423.JONT01000001_gene2005 6.133e-17 87.0 COG0471@1|root,COG2271@1|root,COG0471@2|Bacteria,COG2271@2|Bacteria,1TRHT@1239|Firmicutes,24C2D@186801|Clostridia,263AG@186807|Peptococcaceae 186801|Clostridia G Major Facilitator - - - - - - - - - - - - MFS_1 DYD2_k127_2345617_1 1288494.EBAPG3_26350 5.502e-142 463.0 COG0265@1|root,COG3016@1|root,COG0265@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,2VPEA@28216|Betaproteobacteria,3729T@32003|Nitrosomonadales 28216|Betaproteobacteria O pdz dhr glgf - - - - - - - - - - - - Cofac_haem_bdg,PDZ_2 DYD2_k127_2345617_0 1288494.EBAPG3_26360 4.95e-261 825.0 COG0308@1|root,COG0308@2|Bacteria,1PVVK@1224|Proteobacteria,2VIU3@28216|Betaproteobacteria,3722N@32003|Nitrosomonadales 28216|Betaproteobacteria M Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 DYD2_k127_2345617_2 876269.ARWA01000001_gene1195 6.752e-100 334.0 COG4122@1|root,COG4122@2|Bacteria,1R9D7@1224|Proteobacteria,2U823@28211|Alphaproteobacteria,3NCP7@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 DYD2_k127_2376571_4 1304880.JAGB01000003_gene1226 9.52e-16 76.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 186801|Clostridia J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD2_k127_2376571_3 1217718.ALOU01000051_gene3010 1.565e-71 250.0 COG1028@1|root,COG1028@2|Bacteria,1R3ZC@1224|Proteobacteria,2VMWV@28216|Betaproteobacteria,1K5NS@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 DYD2_k127_2376571_2 1123487.KB892840_gene76 8.57e-81 274.0 COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria,2KVM0@206389|Rhodocyclales 206389|Rhodocyclales C Pyruvate ferredoxin/flavodoxin oxidoreductase padE - 1.2.1.58 ko:K18357 ko00360,map00360 - R02450 RC00004,RC02860 br01601,ko00000,ko00001,ko01000 - - - POR DYD2_k127_2376571_0 395495.Lcho_2150 7.057e-211 661.0 COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria,1KK3S@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Pyruvate:ferredoxin oxidoreductase core domain II porA - 1.2.7.1 ko:K00169 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N DYD2_k127_2376571_1 1123487.KB892840_gene74 1.311e-175 554.0 COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria,2KVZU@206389|Rhodocyclales 206389|Rhodocyclales C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain padI - 1.2.1.58 ko:K18356 ko00360,map00360 - R02450 RC00004,RC02860 br01601,ko00000,ko00001,ko01000 - - - Fer4_11,Fer4_6,TPP_enzyme_C DYD2_k127_2391379_7 105559.Nwat_0789 1.275e-08 62.0 2DR6H@1|root,33ADR@2|Bacteria,1NHEA@1224|Proteobacteria,1SW2J@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2391379_6 365046.Rta_30720 3.758e-66 236.0 28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2VQ6Y@28216|Betaproteobacteria,4ADNP@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2391379_8 202952.BBLI01000008_gene828 2.14e-08 55.0 2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2391379_0 1123392.AQWL01000008_gene1243 2.075e-194 617.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,1KSPK@119069|Hydrogenophilales 119069|Hydrogenophilales J tRNA synthetases class I (E and Q), catalytic domain - - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c DYD2_k127_2391379_2 1380394.JADL01000002_gene1716 4.146e-118 385.0 COG0726@1|root,COG0726@2|Bacteria,1MWYU@1224|Proteobacteria,2VFEE@28211|Alphaproteobacteria,2JVDI@204441|Rhodospirillales 204441|Rhodospirillales G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_2391379_1 1207063.P24_16230 1.77e-157 512.0 COG0405@1|root,COG0405@2|Bacteria,1MXXD@1224|Proteobacteria,2TSB2@28211|Alphaproteobacteria,2JQ6M@204441|Rhodospirillales 204441|Rhodospirillales E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD2_k127_2391379_5 1120956.JHZK01000002_gene1025 8.599e-88 301.0 COG0673@1|root,COG0673@2|Bacteria,1PGFP@1224|Proteobacteria,2V8DN@28211|Alphaproteobacteria,1JQA3@119043|Rhodobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_2391379_3 1380391.JIAS01000020_gene1437 3.171e-111 372.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,2JPPT@204441|Rhodospirillales 204441|Rhodospirillales E FAD dependent oxidoreductase - - - - - - - - - - - - DAO DYD2_k127_2391379_4 1121405.dsmv_0576 3.957e-104 346.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PS7@68525|delta/epsilon subdivisions,2WMMC@28221|Deltaproteobacteria,2MKY8@213118|Desulfobacterales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 DYD2_k127_2440524_5 375286.mma_0398 3.765e-84 284.0 COG0664@1|root,COG0664@2|Bacteria,1R64V@1224|Proteobacteria,2VJXN@28216|Betaproteobacteria,472QZ@75682|Oxalobacteraceae 28216|Betaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding DYD2_k127_2440524_2 296591.Bpro_2797 2.439e-261 813.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAW5@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_2440524_8 1038858.AXBA01000023_gene405 3.078e-41 160.0 2BKYI@1|root,32FF5@2|Bacteria,1MY1A@1224|Proteobacteria,2U1KI@28211|Alphaproteobacteria,3EZUF@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD2_k127_2440524_4 204773.HEAR0348 7.145e-157 501.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,4765G@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_2440524_6 383372.Rcas_4299 2.024e-44 174.0 COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi 200795|Chloroflexi P PFAM sodium calcium exchanger membrane region - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD2_k127_2440524_7 639282.DEFDS_2094 8.822e-43 169.0 COG0530@1|root,COG0530@2|Bacteria,2GEW4@200930|Deferribacteres 200930|Deferribacteres P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD2_k127_2440524_1 395964.KE386496_gene2969 3.903e-295 912.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,3NASQ@45404|Beijerinckiaceae 28211|Alphaproteobacteria F formate-tetrahydrofolate ligase activity fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS DYD2_k127_2440524_0 977880.RALTA_B1495 0.0 1437.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,1K6SR@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA1 - 1.17.1.9,1.17.99.7 ko:K00123,ko:K22015 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD2_k127_2440524_3 1000565.METUNv1_01355 6.05e-179 565.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,2KVUQ@206389|Rhodocyclales 206389|Rhodocyclales C 24 kD subunit - - 1.17.1.9 ko:K00122 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB DYD2_k127_2440524_9 886293.Sinac_4160 3.313e-29 121.0 COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes 203682|Planctomycetes O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD2_k127_2502619_3 1205680.CAKO01000037_gene1197 1.564e-56 205.0 COG2175@1|root,COG2175@2|Bacteria,1NTZJ@1224|Proteobacteria,2U8WF@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - - - - - - - - - - TauD DYD2_k127_2502619_5 1100720.ALKN01000024_gene1474 1.189e-39 157.0 COG1073@1|root,COG1073@2|Bacteria,1N03B@1224|Proteobacteria,2VV1P@28216|Betaproteobacteria,4AFPY@80864|Comamonadaceae 28216|Betaproteobacteria S alpha beta - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 DYD2_k127_2502619_2 762376.AXYL_06850 2.679e-63 229.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T5N5@506|Alcaligenaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_2502619_4 1121861.KB899913_gene2171 1.172e-47 181.0 COG1028@1|root,COG1028@2|Bacteria,1MWCY@1224|Proteobacteria,2TT44@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_2502619_7 1122939.ATUD01000003_gene3529 6.451e-18 93.0 COG2514@1|root,COG2514@2|Bacteria,2HNS6@201174|Actinobacteria,4CPZV@84995|Rubrobacteria 84995|Rubrobacteria S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase DYD2_k127_2502619_0 1123368.AUIS01000018_gene729 1.641e-172 557.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,2NC1Z@225057|Acidithiobacillales 225057|Acidithiobacillales P major facilitator superfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 DYD2_k127_2502619_6 870187.Thini_2495 1.341e-30 126.0 COG3620@1|root,COG3620@2|Bacteria,1QVZN@1224|Proteobacteria,1T2PH@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Mobile mystery protein A - - - - - - - - - - - - HTH_3 DYD2_k127_2502619_1 713586.KB900536_gene2119 3.146e-64 233.0 COG2184@1|root,COG2184@2|Bacteria,1RAVF@1224|Proteobacteria,1S5YI@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Mobile mystery protein B - - - - - - - - - - - - Fic DYD2_k127_2502619_8 1205680.CAKO01000037_gene1197 5.62e-16 84.0 COG2175@1|root,COG2175@2|Bacteria,1NTZJ@1224|Proteobacteria,2U8WF@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - - - - - - - - - - TauD DYD2_k127_2503555_18 1205680.CAKO01000037_gene1197 2.93e-56 205.0 COG2175@1|root,COG2175@2|Bacteria,1NTZJ@1224|Proteobacteria,2U8WF@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - - - - - - - - - - TauD DYD2_k127_2503555_13 351607.Acel_0890 1.911e-75 266.0 COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,4EU2M@85013|Frankiales 201174|Actinobacteria S Belongs to the UPF0255 family - - - - - - - - - - - - DUF1100,Hydrolase_4 DYD2_k127_2503555_10 75379.Tint_2645 1.402e-84 284.0 COG1142@1|root,COG1142@2|Bacteria,1MWE1@1224|Proteobacteria,2VJ9U@28216|Betaproteobacteria,1KKF6@119065|unclassified Burkholderiales 28216|Betaproteobacteria C 4Fe-4S dicluster domain - - - ko:K05796 - - - - ko00000 - - - Fer4,Fer4_11,Fer4_4,Fer4_6,Fer4_9 DYD2_k127_2503555_0 62928.azo2930 0.0 1049.0 COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,2VJ8P@28216|Betaproteobacteria,2KVX2@206389|Rhodocyclales 206389|Rhodocyclales C aldehyde ferredoxin oxidoreductase aorA - 1.2.7.5 ko:K03738 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00309 R08571 RC00242 ko00000,ko00001,ko00002,ko01000 - - - AFOR_C,AFOR_N DYD2_k127_2503555_2 1000565.METUNv1_01510 4.009e-162 521.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2VKIS@28216|Betaproteobacteria,2KVRE@206389|Rhodocyclales 206389|Rhodocyclales S FAD-dependent pyridine - - - - - - - - - - - - Pyr_redox_2 DYD2_k127_2503555_19 395495.Lcho_1819 1.423e-24 108.0 COG2104@1|root,COG2104@2|Bacteria,1N9VX@1224|Proteobacteria,2VVYE@28216|Betaproteobacteria,1KMP9@119065|unclassified Burkholderiales 28216|Betaproteobacteria H Mut7-C ubiquitin - - - - - - - - - - - - ThiS,Ub-Mut7C DYD2_k127_2503555_20 1121920.AUAU01000009_gene1912 8.062e-21 96.0 2EUZI@1|root,33NER@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_2503555_11 1205680.CAKO01000042_gene5417 2.293e-82 284.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_2503555_15 525904.Tter_0116 3.27e-63 234.0 COG3525@1|root,COG3525@2|Bacteria,2NPTI@2323|unclassified Bacteria 2|Bacteria G beta-N-acetylglucosaminidase hyl GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 2.3.1.48,3.2.1.169,3.2.1.35 ko:K01197,ko:K15719 ko00531,ko01100,ko04931,map00531,map01100,map04931 M00076,M00077 R07824,R07825,R09672,R09673,R10905 RC00059,RC00397,RC00451,RC00746 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 - GH84 - F5_F8_type_C,Glyco_hydro_20b,NAGidase DYD2_k127_2503555_14 751944.HALDL1_15305 4.366e-74 261.0 COG2513@1|root,arCOG00582@2157|Archaea,2XTE9@28890|Euryarchaeota,23S2J@183963|Halobacteria 183963|Halobacteria G COG2513 PEP phosphonomutase and related enzymes aceA GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - PEP_mutase DYD2_k127_2503555_16 1297863.APJF01000030_gene820 1.519e-61 228.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria,3JR8H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Major Facilitator Superfamily MA20_02120 - - - - - - - - - - - MFS_1 DYD2_k127_2503555_1 1082931.KKY_3758 1.533e-235 741.0 COG0028@1|root,COG0028@2|Bacteria,1PGJD@1224|Proteobacteria,2V7UA@28211|Alphaproteobacteria,3N91E@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_2503555_21 1236542.BALM01000002_gene956 3.496e-13 72.0 2DFQC@1|root,2ZSNH@2|Bacteria,1P681@1224|Proteobacteria,1SU5V@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2503555_7 1125973.JNLC01000010_gene1490 2.996e-111 375.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD2_k127_2503555_12 62928.azo0921 4.017e-78 277.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,2KY3Z@206389|Rhodocyclales 206389|Rhodocyclales G TRAP-type C4-dicarboxylate transport system, large permease - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM DYD2_k127_2503555_22 714961.BFZC1_05148 9.996e-07 59.0 COG3090@1|root,COG3090@2|Bacteria,1VBG4@1239|Firmicutes,4HHAW@91061|Bacilli,3IXYE@400634|Lysinibacillus 91061|Bacilli G C4-dicarboxylate ABC transporter permease - - - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ DYD2_k127_2503555_4 1205680.CAKO01000029_gene5184 5.751e-122 402.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,2JQ3B@204441|Rhodospirillales 204441|Rhodospirillales ET general L-amino acid-binding periplasmic protein AapJ - - - ko:K09969 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 DYD2_k127_2503555_8 1121861.KB899912_gene973 6.127e-107 359.0 COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2TR7G@28211|Alphaproteobacteria,2JQ13@204441|Rhodospirillales 204441|Rhodospirillales E acid transport system permease - - - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 DYD2_k127_2503555_5 414684.RC1_3125 1.013e-118 396.0 COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria,2JPI5@204441|Rhodospirillales 204441|Rhodospirillales E COG0765 ABC-type amino acid transport system, permease component - - - ko:K09971 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 DYD2_k127_2503555_6 1182590.BN5_03013 8.394e-115 374.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1YEN3@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E ATPases associated with a variety of cellular activities yhdZ GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 ko:K02028,ko:K02029,ko:K09972 ko02010,map02010 M00232,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - iJN746.PP_1300 ABC_tran DYD2_k127_2503555_9 208444.JNYY01000007_gene8025 1.908e-100 341.0 COG0498@1|root,COG0498@2|Bacteria,2GNZD@201174|Actinobacteria,4DZGT@85010|Pseudonocardiales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_2503555_17 631454.N177_3038 9.928e-57 215.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TVAX@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Aminotran_5 DYD2_k127_2503555_3 172088.AUGA01000005_gene7735 9.014e-141 458.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,3JSRD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C FMN-dependent dehydrogenase lldD2 - 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 - R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh DYD2_k127_2503555_25 94624.Bpet2685 0.000158 44.0 COG3181@1|root,COG3181@2|Bacteria,1NP0J@1224|Proteobacteria,2VHTG@28216|Betaproteobacteria,3T2SQ@506|Alcaligenaceae 28216|Betaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_2569439_42 196490.AUEZ01000017_gene3220 0.0001254 46.0 COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2TTXF@28211|Alphaproteobacteria,3JRB1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 DYD2_k127_2569439_41 525904.Tter_1676 7.828e-05 46.0 COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria 2|Bacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen bcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD2_k127_2569439_38 926561.KB900618_gene331 1.108e-24 106.0 COG1225@1|root,COG1225@2|Bacteria,1UV64@1239|Firmicutes,24HTS@186801|Clostridia,3WBX0@53433|Halanaerobiales 186801|Clostridia O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD2_k127_2569439_7 331869.BAL199_22262 1.48e-162 522.0 COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - DYD2_k127_2569439_21 1095769.CAHF01000021_gene943 2.724e-69 241.0 COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2VVC1@28216|Betaproteobacteria 28216|Betaproteobacteria E Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 DYD2_k127_2569439_15 257310.BB1585 3.038e-81 280.0 COG0697@1|root,COG0697@2|Bacteria,1MV7Y@1224|Proteobacteria,2VR8Q@28216|Betaproteobacteria 28216|Betaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_2569439_33 795666.MW7_2050 3.355e-47 175.0 COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,2VT83@28216|Betaproteobacteria,1KI6D@119060|Burkholderiaceae 28216|Betaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodC - 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu DYD2_k127_2569439_16 1380394.JADL01000005_gene5674 7.531e-79 271.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2TS1B@28211|Alphaproteobacteria,2JTGR@204441|Rhodospirillales 204441|Rhodospirillales O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 DYD2_k127_2569439_8 1485544.JQKP01000002_gene1603 1.294e-144 478.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,MHYT DYD2_k127_2569439_31 296591.Bpro_2056 2.973e-48 187.0 COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity cpeZ - - ko:K05384,ko:K05386 ko00196,ko01100,map00196,map01100 - - - ko00000,ko00001,ko00194 - - - HEAT_2 DYD2_k127_2569439_5 1288494.EBAPG3_4650 1.075e-180 574.0 COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2VKYD@28216|Betaproteobacteria,37424@32003|Nitrosomonadales 28216|Betaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_2569439_22 342113.DM82_6119 1.461e-61 217.0 COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VSH3@28216|Betaproteobacteria,1K72M@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM DGPFAETKE family protein - - - - - - - - - - - - YCII DYD2_k127_2569439_19 748247.AZKH_0156 9.173e-73 251.0 COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2VRX6@28216|Betaproteobacteria,2KWX0@206389|Rhodocyclales 206389|Rhodocyclales S Glyoxalase-like domain - - - ko:K04750 - - - - ko00000 - - - Glyoxalase DYD2_k127_2569439_27 1288494.EBAPG3_4640 3.672e-53 196.0 COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,2WA6I@28216|Betaproteobacteria,3749W@32003|Nitrosomonadales 28216|Betaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII DYD2_k127_2569439_20 331869.BAL199_14502 4.77e-70 241.0 COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,2TSWJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 DYD2_k127_2569439_32 153948.NAL212_2253 9.755e-48 174.0 COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,2VWKN@28216|Betaproteobacteria 28216|Betaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII DYD2_k127_2569439_4 1380394.JADL01000014_gene240 3.127e-206 646.0 COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,2JRNW@204441|Rhodospirillales 204441|Rhodospirillales S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - - DYD2_k127_2569439_36 1454004.AW11_01675 8.316e-32 129.0 COG1977@1|root,COG1977@2|Bacteria,1N9QE@1224|Proteobacteria,2VVR6@28216|Betaproteobacteria 28216|Betaproteobacteria H ThiS family - - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD2_k127_2569439_12 748247.AZKH_p0450 1.861e-90 304.0 COG0705@1|root,COG0705@2|Bacteria,1RJYI@1224|Proteobacteria,2W1AJ@28216|Betaproteobacteria,2KXTX@206389|Rhodocyclales 206389|Rhodocyclales S Rhomboid family - - - - - - - - - - - - Rhomboid DYD2_k127_2569439_10 1380394.JADL01000003_gene5214 6.449e-137 447.0 COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2U0IN@28211|Alphaproteobacteria,2JRJQ@204441|Rhodospirillales 204441|Rhodospirillales F Amidohydrolase family - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_3 DYD2_k127_2569439_34 204669.Acid345_3876 4.485e-42 158.0 COG5580@1|root,COG5580@2|Bacteria,3Y90D@57723|Acidobacteria,2JNT0@204432|Acidobacteriia 204432|Acidobacteriia O Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD2_k127_2569439_18 756067.MicvaDRAFT_1483 4.949e-75 262.0 COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,1H7NZ@1150|Oscillatoriales 1117|Cyanobacteria G SMP-30/Gluconolaconase/LRE-like region - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD2_k127_2569439_40 1123261.AXDW01000007_gene2332 5.047e-09 67.0 COG0346@1|root,COG0346@2|Bacteria,1RGZ8@1224|Proteobacteria,1S66M@1236|Gammaproteobacteria,1X73S@135614|Xanthomonadales 135614|Xanthomonadales E Glyoxalase-like domain - - - ko:K08234 - - - - ko00000 - - - Glyoxalase DYD2_k127_2569439_24 1532558.JL39_00915 1.505e-60 222.0 COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_2569439_3 1144310.PMI07_005449 1.446e-208 669.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,4BCQJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA,TctB DYD2_k127_2569439_2 1101195.Meth11DRAFT_2482 6.08e-229 721.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VQSY@28216|Betaproteobacteria 28216|Betaproteobacteria CH PFAM monooxygenase FAD-binding pcpB - 1.14.13.127 ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06786,R06787 RC00236 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD2_k127_2569439_25 450851.PHZ_c1932 1.729e-55 198.0 COG0346@1|root,COG0346@2|Bacteria,1RIBY@1224|Proteobacteria,2UAIH@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD2_k127_2569439_29 1122919.KB905616_gene200 2.074e-49 192.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,26TUC@186822|Paenibacillaceae 91061|Bacilli EGP Multidrug transporter mdtG - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr DYD2_k127_2569439_14 762376.AXYL_06111 6.62e-83 281.0 COG3576@1|root,COG3576@2|Bacteria,1MWG9@1224|Proteobacteria,2VQ6P@28216|Betaproteobacteria,3T5FN@506|Alcaligenaceae 28216|Betaproteobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx DYD2_k127_2569439_1 105559.Nwat_0513 4.986e-245 772.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1WW9C@135613|Chromatiales 135613|Chromatiales C belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.8 ko:K00128,ko:K00130 ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135,M00555 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_2569439_35 1105367.CG50_01235 1.317e-32 142.0 COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,2TT29@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0006 Xaa-Pro aminopeptidase - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 DYD2_k127_2569439_13 1254432.SCE1572_12450 7.417e-87 299.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales 28221|Deltaproteobacteria E Threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase DYD2_k127_2569439_28 1122164.JHWF01000026_gene356 6.692e-53 198.0 COG3219@1|root,COG3219@2|Bacteria,1MZS2@1224|Proteobacteria,1S8M2@1236|Gammaproteobacteria,1JCK9@118969|Legionellales 118969|Legionellales S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 DYD2_k127_2569439_11 1122603.ATVI01000010_gene929 4.99e-125 406.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1X35S@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0276 family - - - ko:K09930 - - - - ko00000 - - - DUF692 DYD2_k127_2569439_39 522306.CAP2UW1_4158 4.033e-18 86.0 2EB3T@1|root,3354H@2|Bacteria,1PVDU@1224|Proteobacteria,2VYHR@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2569439_0 1120983.KB894571_gene2343 4.918e-294 936.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,1JNQT@119043|Rhodobiaceae 28211|Alphaproteobacteria CE DNA-binding domain of Proline dehydrogenase putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg DYD2_k127_2569439_23 314265.R2601_14365 1.501e-61 227.0 COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,2TVGQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria M protein conserved in bacteria - - - - - - - - - - - - MORN DYD2_k127_2569439_26 264198.Reut_B4214 1.745e-55 208.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_2569439_6 675635.Psed_3035 2.054e-170 546.0 COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,4E8N2@85010|Pseudonocardiales 201174|Actinobacteria I Coenzyme A transferase pcaJ - 2.8.3.5,2.8.3.6 ko:K01027,ko:K01029,ko:K01032 ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120 - R00410,R02990 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans DYD2_k127_2569439_9 1005048.CFU_1643 3.935e-139 447.0 COG0596@1|root,COG0596@2|Bacteria,1MWT6@1224|Proteobacteria,2VHJW@28216|Betaproteobacteria,475ZN@75682|Oxalobacteraceae 28216|Betaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_2569439_37 580332.Slit_2044 2.116e-25 107.0 COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria,44WNR@713636|Nitrosomonadales 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - - DYD2_k127_2569439_17 670292.JH26_17580 3.97e-76 263.0 COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VG84@28211|Alphaproteobacteria 28211|Alphaproteobacteria S NAD(P)H-dependent FMN reductase - - - - - - - - - - - - FMN_red DYD2_k127_2569439_30 977880.RALTA_A0507 1.265e-48 180.0 2CESE@1|root,32S0D@2|Bacteria,1RHTD@1224|Proteobacteria,2VSJ5@28216|Betaproteobacteria,1K83E@119060|Burkholderiaceae 28216|Betaproteobacteria S Glycine-zipper domain - - - - - - - - - - - - Gly-zipper_OmpA,Gly-zipper_YMGG DYD2_k127_2597156_2 264198.Reut_B4136 9.841e-58 207.0 COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VMND@28216|Betaproteobacteria,1K120@119060|Burkholderiaceae 28216|Betaproteobacteria G Periplasmic binding proteins and sugar binding domain of LacI family rbsB - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 DYD2_k127_2597156_3 1038867.AXAY01000011_gene5247 2.117e-21 100.0 COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2U4YP@28211|Alphaproteobacteria,3JWQ0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MA20_25940 - - - - - - - - - - - Glyoxalase DYD2_k127_2597156_1 1485544.JQKP01000008_gene1754 3.759e-117 396.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,44VTV@713636|Nitrosomonadales 28216|Betaproteobacteria M TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family oprM - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - OEP DYD2_k127_2597156_0 1000565.METUNv1_02702 0.0 1461.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,2KVA4@206389|Rhodocyclales 206389|Rhodocyclales U efflux pump - - - ko:K18138,ko:K18146 ko01501,ko01503,map01501,map01503 M00647,M00649,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.40 - - ACR_tran DYD2_k127_2597156_4 398767.Glov_1391 1.344e-12 69.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2X5J8@28221|Deltaproteobacteria,43SW4@69541|Desulfuromonadales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD2_k127_2604656_10 1123393.KB891333_gene2539 2.328e-22 98.0 2C5IZ@1|root,33B4P@2|Bacteria,1NPIC@1224|Proteobacteria,2VVUV@28216|Betaproteobacteria 28216|Betaproteobacteria M Glycine zipper 2TM domain osmB - - ko:K04062 - - - - ko00000 - - - Rick_17kDa_Anti DYD2_k127_2604656_17 640081.Dsui_2867 1.48e-05 54.0 COG3133@1|root,COG3133@2|Bacteria,1RK6D@1224|Proteobacteria,2VU04@28216|Betaproteobacteria,2KWUY@206389|Rhodocyclales 206389|Rhodocyclales M Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti DYD2_k127_2604656_7 1123393.KB891316_gene1172 6.709e-55 207.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,1KRPH@119069|Hydrogenophilales 119069|Hydrogenophilales Q MlaC protein - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD2_k127_2604656_2 1266925.JHVX01000009_gene96 4.857e-126 408.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,374MX@32003|Nitrosomonadales 28216|Betaproteobacteria M Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD2_k127_2604656_9 338969.Rfer_0074 1.33e-22 98.0 2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria,4AFCE@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2604656_4 525904.Tter_0340 1.399e-82 282.0 COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria 2|Bacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N DYD2_k127_2604656_12 748247.AZKH_2001 2.201e-21 94.0 2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2VVYY@28216|Betaproteobacteria,2KXJ5@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF3309) - - - - - - - - - - - - DUF3309 DYD2_k127_2604656_14 944435.AXAJ01000004_gene2317 8.638e-12 70.0 2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria,2VXU8@28216|Betaproteobacteria,1KB1T@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3096) - - - - - - - - - - - - DUF3096 DYD2_k127_2604656_16 1123252.ATZF01000014_gene4193 6.468e-08 64.0 COG3266@1|root,COG3266@2|Bacteria,1VG02@1239|Firmicutes,4HNMK@91061|Bacilli 91061|Bacilli M Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen,DUF2479,PTR DYD2_k127_2604656_8 314230.DSM3645_25437 2.104e-54 202.0 COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,2IXG1@203682|Planctomycetes 203682|Planctomycetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg DYD2_k127_2604656_15 946483.Cenrod_1439 5.293e-11 64.0 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like - - - - - - - - - - - - CsbD DYD2_k127_2604656_13 1266925.JHVX01000001_gene2467 8.059e-13 70.0 COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,373KZ@32003|Nitrosomonadales 28216|Betaproteobacteria S Belongs to the UPF0337 (CsbD) family - - - - - - - - - - - - CsbD DYD2_k127_2604656_5 1123393.KB891333_gene2538 3.071e-76 264.0 COG0664@1|root,COG0664@2|Bacteria,1RAF3@1224|Proteobacteria,2VQIC@28216|Betaproteobacteria 28216|Betaproteobacteria K Crp-like helix-turn-helix domain - - - - - - - - - - - - HTH_Crp_2 DYD2_k127_2604656_6 614083.AWQR01000012_gene1324 8.589e-65 228.0 COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA DYD2_k127_2604656_3 1123073.KB899241_gene2409 3.823e-106 349.0 COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria,1X5M5@135614|Xanthomonadales 135614|Xanthomonadales T Crp-like helix-turn-helix domain - - - - - - - - - - - - HTH_Crp_2,cNMP_binding DYD2_k127_2604656_11 864073.HFRIS_017307 3.745e-22 98.0 COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,4750Y@75682|Oxalobacteraceae 28216|Betaproteobacteria S Belongs to the UPF0337 (CsbD) family - - - - - - - - - - - - CsbD DYD2_k127_2604656_1 517417.Cpar_1700 2.438e-218 684.0 COG3004@1|root,COG3004@2|Bacteria,1FDWE@1090|Chlorobi 1090|Chlorobi P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 DYD2_k127_2604656_0 1131814.JAFO01000001_gene3315 0.0 3469.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,3EYBF@335928|Xanthobacteraceae 28211|Alphaproteobacteria G Glycosyl hydrolase 36 superfamily, catalytic domain ndvB GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 ko:K13688,ko:K18786 - - R10832 RC00397 ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase DYD2_k127_2637550_32 1380347.JNII01000006_gene1564 1.284e-08 57.0 COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4ETZM@85013|Frankiales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 DYD2_k127_2637550_20 1144319.PMI16_04926 1.974e-60 218.0 COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRBV@28216|Betaproteobacteria,478XB@75682|Oxalobacteraceae 28216|Betaproteobacteria T helix_turn_helix, Lux Regulon - - - ko:K14979 ko02020,map02020 M00663 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg DYD2_k127_2637550_27 1043493.BBLU01000018_gene1547 4.605e-18 89.0 COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria 201174|Actinobacteria T response regulator - - - - - - - - - - - - GerE,Response_reg DYD2_k127_2637550_10 572477.Alvin_2265 2.485e-115 389.0 COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,1RNVN@1236|Gammaproteobacteria,1WXQU@135613|Chromatiales 135613|Chromatiales V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_2637550_18 1112217.PPL19_14310 1.069e-62 229.0 COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,1S275@1236|Gammaproteobacteria 1236|Gammaproteobacteria V abc transporter atp-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_2637550_24 391595.RLO149_c008850 1.209e-40 160.0 COG3495@1|root,COG3495@2|Bacteria,1RB8H@1224|Proteobacteria,2UAGA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3299) - - - ko:K09950 - - - - ko00000 - - - DUF3299 DYD2_k127_2637550_19 1123060.JONP01000026_gene3444 1.272e-60 224.0 COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2TVSI@28211|Alphaproteobacteria,2JRND@204441|Rhodospirillales 204441|Rhodospirillales M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD2_k127_2637550_9 279714.FuraDRAFT_0693 3.222e-131 428.0 COG0697@1|root,COG0697@2|Bacteria,1N3FA@1224|Proteobacteria,2VHAD@28216|Betaproteobacteria 28216|Betaproteobacteria EG metabolite transporter cnrT - - - - - - - - - - - EamA DYD2_k127_2637550_6 102232.GLO73106DRAFT_00034120 1.408e-162 525.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD2_k127_2637550_28 1366050.N234_35130 4.771e-17 82.0 COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,2VN2K@28216|Betaproteobacteria,1K7D3@119060|Burkholderiaceae 28216|Betaproteobacteria P Iron/manganese superoxide dismutases, C-terminal domain - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Rhodanese,Sod_Fe_C DYD2_k127_2637550_14 580332.Slit_2559 4.71e-85 284.0 COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria,44W9X@713636|Nitrosomonadales 28216|Betaproteobacteria C PFAM NADH ubiquinone oxidoreductase 20 kDa subunit hyfI - - - - - - - - - - - Oxidored_q6 DYD2_k127_2637550_4 1163617.SCD_n02026 7.099e-215 678.0 COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria 28216|Betaproteobacteria C Respiratory-chain NADH dehydrogenase, 49 Kd subunit hyfG - - - - - - - - - - - Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases DYD2_k127_2637550_1 1163617.SCD_n02025 9.405e-250 788.0 COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria 28216|Betaproteobacteria CP NADH Ubiquinone plastoquinone (Complex I) hyfF - - ko:K12141 - - - - ko00000,ko01000 - - - Proton_antipo_M DYD2_k127_2637550_13 1163617.SCD_n02024 6.079e-86 294.0 COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria 28216|Betaproteobacteria C hydrogenase 4 membrane hyfE - - ko:K12140 - - - - ko00000,ko01000 - - - - DYD2_k127_2637550_7 1163617.SCD_n02023 5.234e-142 467.0 COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria 28216|Betaproteobacteria C NADH dehydrogenase hyfD - - - - - - - - - - - NADHdh DYD2_k127_2637550_2 580332.Slit_2564 2.481e-233 739.0 COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria,44WCY@713636|Nitrosomonadales 28216|Betaproteobacteria CP PFAM NADH Ubiquinone plastoquinone (complex I) hyfB - - - - - - - - - - - Proton_antipo_M DYD2_k127_2637550_23 1121396.KB892957_gene3216 2.028e-43 160.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2WJAJ@28221|Deltaproteobacteria,2MHTN@213118|Desulfobacterales 28221|Deltaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family lpdA-4 - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim DYD2_k127_2637550_0 215803.DB30_4886 0.0 1318.0 COG1429@1|root,COG1429@2|Bacteria,1QX7D@1224|Proteobacteria,43C0E@68525|delta/epsilon subdivisions,2X7B3@28221|Deltaproteobacteria,2Z3EW@29|Myxococcales 28221|Deltaproteobacteria H Glycosyl hydrolase family 63 C-terminal domain - - - - - - - - - - - - Glyco_hydro_63 DYD2_k127_2637550_5 381666.H16_B1765 2.397e-208 656.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VHC1@28216|Betaproteobacteria,1K09M@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.16.1.1 ko:K00520,ko:K21739 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim DYD2_k127_2637550_30 1246995.AFR_15705 1.008e-14 75.0 COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria 201174|Actinobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_2637550_17 1238182.C882_1732 2.949e-66 241.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,2TT2Q@28211|Alphaproteobacteria,2JR6G@204441|Rhodospirillales 204441|Rhodospirillales S COG0656 Aldo keto reductases, related to diketogulonate reductase - - 1.1.1.346 ko:K06222 - - - - ko00000,ko01000 - - - Aldo_ket_red DYD2_k127_2637550_12 1380394.JADL01000004_gene5745 2.283e-86 294.0 COG0607@1|root,COG4275@1|root,COG0607@2|Bacteria,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TRC3@28211|Alphaproteobacteria,2JPWH@204441|Rhodospirillales 204441|Rhodospirillales P Chromate resistance exported protein - - - - - - - - - - - - Chrome_Resist,Rhodanese DYD2_k127_2637550_16 321332.CYB_1257 4.837e-72 258.0 COG2059@1|root,COG2059@2|Bacteria,1G37Z@1117|Cyanobacteria,1H067@1129|Synechococcus 1117|Cyanobacteria P chromate transport protein chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD2_k127_2637550_3 640081.Dsui_1137 2.532e-218 685.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,2KV7A@206389|Rhodocyclales 206389|Rhodocyclales P Chromate Ion Transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD2_k127_2637550_8 748280.NH8B_0758 1.302e-131 455.0 COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQNU@206351|Neisseriales 206351|Neisseriales T diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 DYD2_k127_2637550_22 1304275.C41B8_16724 1.431e-43 166.0 COG4968@1|root,COG4968@2|Bacteria,1N31J@1224|Proteobacteria,1SS17@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Prokaryotic N-terminal methylation motif - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl DYD2_k127_2637550_33 96561.Dole_0346 5.221e-05 53.0 COG3807@1|root,COG3807@2|Bacteria,1RIYJ@1224|Proteobacteria,42SNK@68525|delta/epsilon subdivisions,2WPNS@28221|Deltaproteobacteria,2MK8E@213118|Desulfobacterales 28221|Deltaproteobacteria S SH3 domain - - - - - - - - - - - - SH3_4 DYD2_k127_2637550_15 323848.Nmul_A0638 8.795e-76 276.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2WGWX@28216|Betaproteobacteria,37279@32003|Nitrosomonadales 28216|Betaproteobacteria T Cache domain - - - - - - - - - - - - GGDEF,HAMP,dCache_1 DYD2_k127_2637550_25 426355.Mrad2831_6138 1.853e-22 102.0 COG0664@1|root,COG4271@1|root,COG0664@2|Bacteria,COG4271@2|Bacteria,1R4Z7@1224|Proteobacteria,2U4YZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Predicted nucleotide-binding protein containing TIR-like domain - - - - - - - - - - - - TIR-like,cNMP_binding DYD2_k127_2637550_21 331869.BAL199_08658 7.058e-56 208.0 COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2U84Q@28211|Alphaproteobacteria,4BQI5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - ko:K07232 - - - - ko00000 - - - ChaC DYD2_k127_2637550_29 638303.Thal_0236 1.118e-16 90.0 COG3369@1|root,COG3369@2|Bacteria 2|Bacteria I Iron-binding zinc finger CDGSH type - - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - zf-CDGSH DYD2_k127_2637550_11 1120983.KB894572_gene2920 1.037e-114 392.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,1JQ5J@119043|Rhodobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD2_k127_2637550_31 935840.JAEQ01000020_gene2339 3.679e-12 78.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2V7D9@28211|Alphaproteobacteria,43KPE@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_6 DYD2_k127_2672011_6 1211115.ALIQ01000234_gene4147 2.39e-41 168.0 COG2271@1|root,COG2271@2|Bacteria,1QVY6@1224|Proteobacteria,2TWTV@28211|Alphaproteobacteria,3NBUK@45404|Beijerinckiaceae 28211|Alphaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_2672011_1 631362.Thi970DRAFT_04432 6.868e-131 429.0 COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1T2D1@1236|Gammaproteobacteria,1X28U@135613|Chromatiales 135613|Chromatiales P Sodium/hydrogen exchanger family - - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger DYD2_k127_2672011_4 1123228.AUIH01000008_gene2428 1.492e-74 269.0 COG2807@1|root,COG2807@2|Bacteria,1NXQ2@1224|Proteobacteria,1RXXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_2672011_7 243233.MCA1510 2.357e-32 130.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1XFPQ@135618|Methylococcales 135618|Methylococcales U Belongs to the N-Me-Phe pilin family - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD2_k127_2672011_3 29540.C481_20726 9.247e-84 289.0 arCOG10131@1|root,arCOG10131@2157|Archaea,2XWNY@28890|Euryarchaeota,23V3W@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - DYD2_k127_2672011_10 1114964.L485_17125 2.088e-12 70.0 2BZD4@1|root,332J5@2|Bacteria,1RC8E@1224|Proteobacteria,2VGHM@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2672011_11 1114964.L485_17125 2.139e-07 57.0 2BZD4@1|root,332J5@2|Bacteria,1RC8E@1224|Proteobacteria,2VGHM@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2672011_9 479434.Sthe_3144 9.089e-29 128.0 COG0346@1|root,COG0346@2|Bacteria,2G8K0@200795|Chloroflexi,27YCV@189775|Thermomicrobia 189775|Thermomicrobia E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_3 DYD2_k127_2672011_5 644966.Tmar_1750 3.521e-46 182.0 COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,24MEW@186801|Clostridia 186801|Clostridia S Tripartite tricarboxylate transporter family receptor - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC DYD2_k127_2672011_8 1174684.EBMC1_17152 8.507e-30 124.0 COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2UK4T@28211|Alphaproteobacteria,2K9ZZ@204457|Sphingomonadales 204457|Sphingomonadales E Glyoxalase-like domain - - - ko:K08234 - - - - ko00000 - - - - DYD2_k127_2672011_0 1231391.AMZF01000037_gene582 4.994e-204 645.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VMVH@28216|Betaproteobacteria,3T60M@506|Alcaligenaceae 28216|Betaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine - - 1.1.1.308 ko:K15509 - - - - ko00000,ko01000 - - - Histidinol_dh DYD2_k127_2672011_2 1231391.AMZF01000037_gene581 1.273e-87 301.0 COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2W1GT@28216|Betaproteobacteria,3T5D6@506|Alcaligenaceae 28216|Betaproteobacteria IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short_C2 DYD2_k127_2672011_12 377629.TERTU_3523 0.0001398 49.0 COG2128@1|root,COG2128@2|Bacteria,1RASD@1224|Proteobacteria,1S391@1236|Gammaproteobacteria,2PNWX@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD2_k127_2672011_13 1210884.HG799463_gene9341 0.000945 43.0 COG2128@1|root,COG2128@2|Bacteria,2IZ92@203682|Planctomycetes 203682|Planctomycetes S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD2_k127_2829563_8 323848.Nmul_A2114 2.264e-68 239.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,372EI@32003|Nitrosomonadales 28216|Betaproteobacteria M Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 DYD2_k127_2829563_15 1266925.JHVX01000006_gene2137 4.644e-25 111.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2VVNP@28216|Betaproteobacteria,373JI@32003|Nitrosomonadales 28216|Betaproteobacteria T BolA-like protein bolA - - ko:K05527 - - - - ko00000,ko03000 - - - BolA DYD2_k127_2829563_7 228410.NE0055 1.324e-75 257.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,372W8@32003|Nitrosomonadales 28216|Betaproteobacteria D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA DYD2_k127_2829563_9 323848.Nmul_A2110 6.779e-61 213.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,373GQ@32003|Nitrosomonadales 28216|Betaproteobacteria C SelR domain msrB - 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 - - - - ko00000,ko01000 - - - SelR DYD2_k127_2829563_2 497321.C664_10782 4.172e-170 548.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,2KV7J@206389|Rhodocyclales 206389|Rhodocyclales C glycolate oxidase subunit GlcD - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 DYD2_k127_2829563_3 1123239.KB898639_gene40 7.252e-149 490.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli 91061|Bacilli EH Belongs to the TPP enzyme family - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_2829563_12 375286.mma_1292 4.011e-39 151.0 2EFUW@1|root,339M2@2|Bacteria,1NJM2@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB DYD2_k127_2829563_0 375286.mma_1293 1.599e-237 743.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,476BH@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_2829563_5 555088.DealDRAFT_2387 6.584e-104 369.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia 186801|Clostridia C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate icd - 1.1.1.41 ko:K00030 ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010 R00709 RC00114 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD2_k127_2829563_4 1380394.JADL01000011_gene4018 7.297e-133 432.0 COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2TRJN@28211|Alphaproteobacteria,2JV65@204441|Rhodospirillales 204441|Rhodospirillales H Ketopantoate reductase PanE/ApbA C terminal - - - - - - - - - - - - ApbA,ApbA_C DYD2_k127_2829563_1 1380394.JADL01000001_gene2487 5.071e-191 607.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TVD2@28211|Alphaproteobacteria,2JV3W@204441|Rhodospirillales 204441|Rhodospirillales E Aconitase family (aconitate hydratase) - - - - - - - - - - - - Aconitase DYD2_k127_2829563_10 1380394.JADL01000001_gene2488 1.354e-56 203.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,2JPTP@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - - - - - - - - - - Aconitase_C DYD2_k127_2829563_11 1123400.KB904754_gene973 2.031e-46 172.0 COG2453@1|root,COG2453@2|Bacteria,1N0H0@1224|Proteobacteria,1S9JV@1236|Gammaproteobacteria,4631Y@72273|Thiotrichales 72273|Thiotrichales T Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - - - - - - - - - - CDKN3,DSPc DYD2_k127_2829563_6 1454004.AW11_03618 6.908e-86 293.0 COG2199@1|root,COG3706@2|Bacteria,1REBC@1224|Proteobacteria,2VV0U@28216|Betaproteobacteria 28216|Betaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF DYD2_k127_2829563_16 864051.BurJ1DRAFT_1943 3.007e-14 74.0 COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,2VXUM@28216|Betaproteobacteria 28216|Betaproteobacteria S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - ParE_toxin DYD2_k127_2829563_17 270374.MELB17_00935 3.462e-13 72.0 2AFGR@1|root,315H2@2|Bacteria,1PVK9@1224|Proteobacteria,1STVA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative addiction module component - - - - - - - - - - - - Unstab_antitox DYD2_k127_2835388_13 29581.BW37_05111 7.724e-43 164.0 COG3134@1|root,COG3134@2|Bacteria,1N0SK@1224|Proteobacteria,2WIIM@28216|Betaproteobacteria,474FG@75682|Oxalobacteraceae 28216|Betaproteobacteria S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti DYD2_k127_2835388_14 1266925.JHVX01000001_gene2468 1.758e-14 76.0 2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,2W8JG@28216|Betaproteobacteria,373T2@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2835388_16 568706.BN118_2925 1.771e-05 48.0 COG5510@1|root,COG5510@2|Bacteria,1PVRA@1224|Proteobacteria,2WBFW@28216|Betaproteobacteria,3T8H1@506|Alcaligenaceae 28216|Betaproteobacteria S Entericidin EcnA/B family ecnA1 - - - - - - - - - - - Entericidin DYD2_k127_2835388_3 1157708.KB907462_gene897 1.081e-183 581.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,4AB2U@80864|Comamonadaceae 28216|Betaproteobacteria I PFAM fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase DYD2_k127_2835388_12 323848.Nmul_A2345 1.247e-45 167.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,373D1@32003|Nitrosomonadales 28216|Betaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD2_k127_2835388_0 1288494.EBAPG3_26720 7.029e-282 874.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,372Q8@32003|Nitrosomonadales 28216|Betaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD2_k127_2835388_15 29581.BW37_00058 7.552e-12 68.0 COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,2VWCP@28216|Betaproteobacteria,4754M@75682|Oxalobacteraceae 28216|Betaproteobacteria S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc DYD2_k127_2835388_10 1123060.JONP01000007_gene4984 4.401e-56 206.0 COG0596@1|root,COG0596@2|Bacteria,1R9EZ@1224|Proteobacteria,2U44G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_2835388_4 1487953.JMKF01000095_gene5137 2.442e-152 486.0 COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1HEHF@1150|Oscillatoriales 1117|Cyanobacteria S Alcohol dehydrogenase GroES-like domain - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_2835388_11 1000565.METUNv1_03628 2.42e-48 181.0 28TB7@1|root,2ZFJR@2|Bacteria,1PACM@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_2835388_5 582744.Msip34_0247 2.862e-133 435.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,2KKBV@206350|Nitrosomonadales 206350|Nitrosomonadales S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 DYD2_k127_2835388_9 1288494.EBAPG3_17670 8.465e-104 342.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,371ZM@32003|Nitrosomonadales 28216|Betaproteobacteria IQ Short-chain dehydrogenase reductase SDR - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 ko:K00059,ko:K03793 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_2835388_6 1562701.BBOF01000059_gene1743 1.35e-129 419.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,1K0VT@119060|Burkholderiaceae 28216|Betaproteobacteria J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA - - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 DYD2_k127_2835388_2 556268.OFAG_02107 3.702e-201 638.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VNWB@28216|Betaproteobacteria,478EE@75682|Oxalobacteraceae 28216|Betaproteobacteria E Aminotransferase class-V - - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD2_k127_2835388_7 279714.FuraDRAFT_1413 2.005e-129 419.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,2KPSF@206351|Neisseriales 206351|Neisseriales E Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR DYD2_k127_2835388_1 243233.MCA0138 2.259e-248 772.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1XDX9@135618|Methylococcales 135618|Methylococcales H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD DYD2_k127_2835388_8 1163617.SCD_n00307 4.498e-124 400.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N DYD2_k127_2847157_1 323848.Nmul_A2468 1.045e-134 431.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,372QB@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN DYD2_k127_2847157_0 999541.bgla_1g05340 2.071e-207 648.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,1K06J@119060|Burkholderiaceae 28216|Betaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm DYD2_k127_2847157_4 498848.TaqDRAFT_3142 3.406e-05 55.0 2EH09@1|root,33ASB@2|Bacteria,1WKPC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 DYD2_k127_2847157_2 1304883.KI912532_gene1136 7.295e-37 145.0 COG3439@1|root,COG3439@2|Bacteria,1RHPD@1224|Proteobacteria,2VV5X@28216|Betaproteobacteria,2KX7Y@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 DYD2_k127_2847157_3 748247.AZKH_0093 1.101e-15 82.0 2EH9R@1|root,33B1M@2|Bacteria,1NH7Y@1224|Proteobacteria,2VXYE@28216|Betaproteobacteria,2KZ7T@206389|Rhodocyclales 206389|Rhodocyclales S KTSC domain - - - - - - - - - - - - KTSC DYD2_k127_2849488_2 697282.Mettu_0878 3.52e-273 858.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XG1W@135618|Methylococcales 135618|Methylococcales V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran DYD2_k127_2849488_7 1266925.JHVX01000002_gene1068 1.026e-91 311.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,372MP@32003|Nitrosomonadales 28216|Betaproteobacteria S Belongs to the GcvT family ygfZ - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C DYD2_k127_2849488_16 1000565.METUNv1_00900 1.114e-11 70.0 2EPNT@1|root,33H9E@2|Bacteria,1NI6Z@1224|Proteobacteria,2VXVE@28216|Betaproteobacteria,2KZ8W@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function (DUF4936) - - - - - - - - - - - - DUF4936 DYD2_k127_2849488_8 243231.GSU0792 1.419e-77 269.0 COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,42QS8@68525|delta/epsilon subdivisions,2WMV7@28221|Deltaproteobacteria,43SGZ@69541|Desulfuromonadales 28221|Deltaproteobacteria S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 DYD2_k127_2849488_4 113395.AXAI01000030_gene2661 1.377e-218 687.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3JSVT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde dehydrogenase - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_2849488_14 1123253.AUBD01000001_gene1715 7.55e-45 170.0 COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,1X5TH@135614|Xanthomonadales 135614|Xanthomonadales S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_10 DYD2_k127_2849488_0 1049564.TevJSym_af00690 1.807e-290 905.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,1RNTD@1236|Gammaproteobacteria,1J9TP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II,adh_short_C2 DYD2_k127_2849488_5 903818.KI912268_gene1722 2.973e-134 436.0 COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria 57723|Acidobacteria E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B DYD2_k127_2849488_9 269799.Gmet_0053 5.298e-72 264.0 COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,43TZR@69541|Desulfuromonadales 28221|Deltaproteobacteria E Transglutaminase/protease-like homologues - - - - - - - - - - - - Transglut_core DYD2_k127_2849488_6 557598.LHK_00699 9.333e-105 345.0 COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,2VJ81@28216|Betaproteobacteria,2KQEX@206351|Neisseriales 206351|Neisseriales IQ KR domain fabG2 - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_2849488_10 1288494.EBAPG3_12840 1.702e-71 245.0 COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,3730C@32003|Nitrosomonadales 28216|Betaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD DYD2_k127_2849488_11 305700.B447_10418 4.17e-62 218.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,2KW90@206389|Rhodocyclales 206389|Rhodocyclales FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam DYD2_k127_2849488_1 1123392.AQWL01000008_gene1259 1.165e-284 897.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,1KRBY@119069|Hydrogenophilales 119069|Hydrogenophilales F GMP synthase C terminal domain guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase DYD2_k127_2849488_3 1304883.KI912532_gene2521 9.962e-231 723.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,2KVFJ@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH DYD2_k127_2849488_17 204773.HEAR1358 2.297e-07 59.0 2BCK1@1|root,32662@2|Bacteria,1RHH4@1224|Proteobacteria,2VSPG@28216|Betaproteobacteria,474KN@75682|Oxalobacteraceae 28216|Betaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 DYD2_k127_2849488_15 675815.VOA_000780 4.381e-20 98.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,1XXAY@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0125 (RnfH) family yfjF - - ko:K09801 - - - - ko00000 - - - Ub-RnfH DYD2_k127_2849488_12 1123487.KB892843_gene800 1.137e-52 190.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,2KW7M@206389|Rhodocyclales 206389|Rhodocyclales I Oligoketide cyclase lipid transport protein - - - - - - - - - - - - Polyketide_cyc DYD2_k127_2849488_13 323848.Nmul_A1203 9.052e-52 186.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,37321@32003|Nitrosomonadales 28216|Betaproteobacteria J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB DYD2_k127_2850514_3 1207063.P24_18716 1.39e-15 87.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,2JTNS@204441|Rhodospirillales 204441|Rhodospirillales S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_2850514_2 643648.Slip_2083 2.126e-44 177.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42KB1@68298|Syntrophomonadaceae 186801|Clostridia C PFAM acyl-CoA dehydrogenase domain protein - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_2850514_0 1429916.X566_18490 1.245e-201 640.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3JSS3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E GMC oxidoreductase MA20_44990 - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N DYD2_k127_2850514_1 1121406.JAEX01000001_gene20 2.058e-49 186.0 COG0349@1|root,COG2827@1|root,COG0349@2|Bacteria,COG2827@2|Bacteria,1REMB@1224|Proteobacteria,42S18@68525|delta/epsilon subdivisions,2WN9J@28221|Deltaproteobacteria,2MAMV@213115|Desulfovibrionales 28221|Deltaproteobacteria L 3'-5' exonuclease - - - - - - - - - - - - DNA_pol_A_exo1 DYD2_k127_2853361_0 748247.AZKH_2605 3.392e-257 805.0 COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,2KY78@206389|Rhodocyclales 28216|Betaproteobacteria EH COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase - - 2.3.3.15 ko:K03852 ko00430,map00430 - R05651 RC02903,RC02909 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_2853361_1 404589.Anae109_1032 8.314e-255 818.0 COG4262@1|root,COG4262@2|Bacteria 2|Bacteria H Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - MFS_1,Spermine_synth DYD2_k127_2853361_10 795666.MW7_1853 2.187e-103 346.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2VRYX@28216|Betaproteobacteria,1K6VH@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 DYD2_k127_2853361_8 1266925.JHVX01000010_gene1319 4.913e-108 357.0 COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,2VN04@28216|Betaproteobacteria,372SJ@32003|Nitrosomonadales 28216|Betaproteobacteria G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin DYD2_k127_2853361_3 1266925.JHVX01000010_gene1318 7.912e-215 675.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,371N1@32003|Nitrosomonadales 28216|Betaproteobacteria E argininosuccinate lyase argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 DYD2_k127_2853361_6 1163617.SCD_n02801 9.181e-124 405.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase algZ - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase DYD2_k127_2853361_14 580332.Slit_0260 4.801e-87 294.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2WEFP@28216|Betaproteobacteria,44V6W@713636|Nitrosomonadales 28216|Betaproteobacteria K LytTr DNA-binding domain algR - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg DYD2_k127_2853361_22 1286093.C266_04914 7.905e-21 99.0 COG0526@1|root,COG0526@2|Bacteria,1NBTN@1224|Proteobacteria,2VW6S@28216|Betaproteobacteria,1KDJ2@119060|Burkholderiaceae 28216|Betaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Thioredoxin_7 DYD2_k127_2853361_7 323848.Nmul_A2690 1.777e-115 380.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,372YX@32003|Nitrosomonadales 28216|Betaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC DYD2_k127_2853361_12 323848.Nmul_A2689 1.667e-90 304.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,371TG@32003|Nitrosomonadales 28216|Betaproteobacteria H uroporphyrinogen III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 DYD2_k127_2853361_15 1454004.AW11_02048 2.545e-66 242.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria 28216|Betaproteobacteria H enzyme of heme biosynthesis hemX - 2.1.1.107,4.2.1.75 ko:K02496,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4,HemX DYD2_k127_2853361_11 1266925.JHVX01000011_gene1467 8.827e-99 343.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,371TK@32003|Nitrosomonadales 28216|Betaproteobacteria H HemY protein N-terminus hemY - - ko:K02498 - - - - ko00000 - - - HemY_N,TPR_12 DYD2_k127_2853361_24 706587.Desti_5217 4.449e-13 68.0 2C1SS@1|root,32YN6@2|Bacteria,1NNFV@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_2853361_23 357808.RoseRS_3426 3.644e-17 83.0 2E90H@1|root,3339X@2|Bacteria,2GB2F@200795|Chloroflexi,377SX@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - DYD2_k127_2853361_20 404589.Anae109_2821 1.653e-40 153.0 COG3791@1|root,COG3791@2|Bacteria,1N7AZ@1224|Proteobacteria 1224|Proteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA DYD2_k127_2853361_5 1266925.JHVX01000011_gene1466 3.858e-137 444.0 COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,372BS@32003|Nitrosomonadales 28216|Betaproteobacteria C Oxidoreductase FAD-binding domain ascD - 1.17.1.1 ko:K00523 ko00520,map00520 - R03391,R03392 RC00230 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 DYD2_k127_2853361_9 323848.Nmul_A2685 1.544e-105 349.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,372CI@32003|Nitrosomonadales 28216|Betaproteobacteria GM PFAM NAD-dependent epimerase dehydratase yeeZ - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N DYD2_k127_2853361_21 497321.C664_19111 1.9e-35 139.0 COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales 206389|Rhodocyclales P protein involved in tolerance to divalent cations cutA1 - - ko:K03926 - - - - ko00000 - - - CutA1 DYD2_k127_2853361_4 522306.CAP2UW1_3579 5.914e-205 657.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KQF7@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_2,Thioredoxin_7 DYD2_k127_2853361_19 1288494.EBAPG3_8790 2.607e-42 162.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,3732S@32003|Nitrosomonadales 28216|Betaproteobacteria CO Thioredoxin-like tlpA - - - - - - - - - - - AhpC-TSA,Redoxin DYD2_k127_2853361_16 1131553.JIBI01000010_gene1378 7.047e-57 202.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,3738V@32003|Nitrosomonadales 28216|Betaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II DYD2_k127_2853361_17 1123392.AQWL01000002_gene1936 6.677e-56 199.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,1KS8I@119069|Hydrogenophilales 119069|Hydrogenophilales I Biotin-requiring enzyme - - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl DYD2_k127_2853361_2 580332.Slit_2856 1.174e-236 737.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,44VMS@713636|Nitrosomonadales 28216|Betaproteobacteria I PFAM Carbamoyl-phosphate synthase L chain ATP-binding accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD2_k127_2853361_13 1163617.SCD_n02784 2.086e-90 306.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria 28216|Betaproteobacteria J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA DYD2_k127_2866710_48 1122605.KB893647_gene283 1.205e-24 105.0 COG0730@1|root,COG1648@1|root,COG0730@2|Bacteria,COG1648@2|Bacteria,4NI81@976|Bacteroidetes 976|Bacteroidetes H COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain) cysG - 1.3.1.76,4.99.1.4 ko:K02304,ko:K07090 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947 RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - NAD_binding_7,Sirohm_synth_M,TauE DYD2_k127_2866710_20 269482.Bcep1808_3218 4.593e-123 413.0 COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,1K19M@119060|Burkholderiaceae 28216|Betaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd,dTDP_sugar_isom DYD2_k127_2866710_34 314345.SPV1_04893 1.7e-70 244.0 COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria 1224|Proteobacteria F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25,2.7.7.4 ko:K00860,ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU DYD2_k127_2866710_29 1485544.JQKP01000002_gene1539 1.438e-95 322.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,44WH1@713636|Nitrosomonadales 28216|Betaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) rfaC - - ko:K02841 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD2_k127_2866710_18 1163617.SCD_n02917 9.084e-147 481.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria 28216|Betaproteobacteria M transferase kdtA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N DYD2_k127_2866710_39 266117.Rxyl_1321 8.171e-48 179.0 COG0212@1|root,COG0212@2|Bacteria 2|Bacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298 5-FTHF_cyc-lig DYD2_k127_2866710_25 1163617.SCD_n02918 5.608e-116 391.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria 28216|Betaproteobacteria MU type I secretion outer membrane protein, TolC - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP DYD2_k127_2866710_31 1163617.SCD_n02919 1.042e-89 301.0 COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria 28216|Betaproteobacteria O protein-L-isoaspartate(D-aspartate) O-methyltransferase pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD2_k127_2866710_47 1198452.Jab_2c08640 6.89e-26 112.0 COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,2VWJI@28216|Betaproteobacteria 28216|Betaproteobacteria T STAS domain - - - ko:K06378 - - - - ko00000 - - - STAS,STAS_2 DYD2_k127_2866710_24 1122604.JONR01000009_gene2309 2.892e-116 385.0 COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - - - - - - - - - - Lactamase_B_2 DYD2_k127_2866710_14 1232683.ADIMK_3832 5.233e-173 566.0 COG2208@1|root,COG4252@1|root,COG2208@2|Bacteria,COG4252@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,46BPT@72275|Alteromonadaceae 1236|Gammaproteobacteria KT Sigma factor PP2C-like phosphatases icfG - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - HAMP,HATPase_c_2,SpoIIE,dCache_1 DYD2_k127_2866710_43 159087.Daro_1992 1.281e-40 161.0 COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,2VU4E@28216|Betaproteobacteria,2KZ0C@206389|Rhodocyclales 206389|Rhodocyclales M OmpA family - - - - - - - - - - - - OmpA DYD2_k127_2866710_44 1122604.JONR01000009_gene2312 4.867e-36 143.0 COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,1SE8D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S FecR protein - - - - - - - - - - - - FecR DYD2_k127_2866710_49 1198452.Jab_2c08590 2.798e-18 91.0 COG2172@1|root,COG2172@2|Bacteria,1PVRF@1224|Proteobacteria,2VYZ5@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase-like ATPase domain - - - - - - - - - - - - HATPase_c_2 DYD2_k127_2866710_0 582744.Msip34_2617 0.0 1074.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,2KKSI@206350|Nitrosomonadales 206350|Nitrosomonadales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM DYD2_k127_2866710_21 614083.AWQR01000055_gene1969 1.56e-122 410.0 COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,4A9MA@80864|Comamonadaceae 28216|Betaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - HlyD_D23 DYD2_k127_2866710_28 795666.MW7_0759 1.565e-97 325.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VIKP@28216|Betaproteobacteria,1K47S@119060|Burkholderiaceae 28216|Betaproteobacteria V abc transporter macB - - ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - ABC_tran,FtsX,MacB_PCD DYD2_k127_2866710_15 795666.MW7_0760 1.997e-171 547.0 COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria 28216|Betaproteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_2866710_50 1328313.DS2_03035 2.936e-10 66.0 2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,468TV@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - BiPBP_C,DUF4124 DYD2_k127_2866710_22 1163617.SCD_n02921 6.517e-119 388.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria 28216|Betaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA DYD2_k127_2866710_37 469383.Cwoe_3536 1.718e-51 197.0 COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria 201174|Actinobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_2866710_35 76114.ebA4122 3.174e-61 215.0 COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,2KWCV@206389|Rhodocyclales 206389|Rhodocyclales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese DYD2_k127_2866710_5 1266925.JHVX01000012_gene1727 6.363e-241 756.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,372EA@32003|Nitrosomonadales 28216|Betaproteobacteria E TIGRFAM glutamine synthetase, type I glnA GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 ko:K01915,ko:K20712 ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253,R06988,R09284 RC00010,RC01754,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N DYD2_k127_2866710_46 85643.Tmz1t_3649 2.38e-30 127.0 2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria,2KWKW@206389|Rhodocyclales 206389|Rhodocyclales S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 DYD2_k127_2866710_19 640081.Dsui_1050 2.245e-124 409.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KUZZ@206389|Rhodocyclales 206389|Rhodocyclales T Signal transduction histidine kinase, nitrogen specific ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 DYD2_k127_2866710_6 640081.Dsui_1051 6.802e-218 684.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KV3K@206389|Rhodocyclales 206389|Rhodocyclales T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains ntrC - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD2_k127_2866710_40 1148.1652812 9.946e-46 166.0 COG2343@1|root,COG2343@2|Bacteria,1G7U6@1117|Cyanobacteria,1H5X1@1142|Synechocystis 1117|Cyanobacteria S Domain of unknown function (DUF427) - - - - - - - - - - - - NTP_transf_9 DYD2_k127_2866710_26 1266925.JHVX01000010_gene1401 1.219e-110 362.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,371UX@32003|Nitrosomonadales 28216|Betaproteobacteria L Exodeoxyribonuclease III xth xthA - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos DYD2_k127_2866710_45 1123392.AQWL01000005_gene3179 6.338e-35 141.0 COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria,1KSYP@119069|Hydrogenophilales 119069|Hydrogenophilales O Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124,Glutaredoxin DYD2_k127_2866710_1 1163617.SCD_n00204 0.0 1013.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria 28216|Betaproteobacteria E PFAM peptidase M3A and M3B, thimet oligopeptidase F prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 DYD2_k127_2866710_8 1163617.SCD_n00209 5.533e-209 655.0 COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria 28216|Betaproteobacteria F dihydroorotase pyrX - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 DYD2_k127_2866710_16 1288494.EBAPG3_28010 2.94e-162 519.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,372F3@32003|Nitrosomonadales 28216|Betaproteobacteria F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD2_k127_2866710_36 1266925.JHVX01000005_gene1856 2.484e-57 204.0 COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,3733Q@32003|Nitrosomonadales 28216|Betaproteobacteria F Phosphoribosyl transferase domain pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran DYD2_k127_2866710_41 1288494.EBAPG3_27990 5.641e-41 156.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,373BU@32003|Nitrosomonadales 28216|Betaproteobacteria J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX DYD2_k127_2866710_32 1266925.JHVX01000005_gene1854 9.596e-82 276.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,372DD@32003|Nitrosomonadales 28216|Betaproteobacteria K Belongs to the UPF0301 (AlgH) family algH - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 DYD2_k127_2866710_9 582744.Msip34_2176 2.121e-204 646.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,2KKBP@206350|Nitrosomonadales 206350|Nitrosomonadales L PFAM DNA photolyase FAD-binding - - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 DYD2_k127_2866710_10 1131553.JIBI01000071_gene2157 6.806e-183 586.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,3728D@32003|Nitrosomonadales 28216|Betaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH DYD2_k127_2866710_13 1454004.AW11_02692 4.524e-177 569.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,1KQBC@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH DYD2_k127_2866710_7 261292.Nit79A3_0468 1.162e-209 661.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,3720Q@32003|Nitrosomonadales 28216|Betaproteobacteria C TrkA-N domain protein trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD2_k127_2866710_33 1123392.AQWL01000002_gene1904 3.415e-71 249.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,1KSFC@119069|Hydrogenophilales 119069|Hydrogenophilales J RNA methyltransferase - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA DYD2_k127_2866710_12 1288494.EBAPG3_18220 1.27e-178 571.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,372FT@32003|Nitrosomonadales 28216|Betaproteobacteria E Belongs to the acetyltransferase family. ArgA subfamily argA - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 DYD2_k127_2866710_3 292415.Tbd_0152 3.513e-281 897.0 COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - 7TMR-DISM_7TM,EAL,GGDEF,HAMP,MASE1,PAS_3,PAS_4,PAS_8,PAS_9 DYD2_k127_2866710_42 1157708.KB907450_gene6083 6.508e-41 153.0 COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,4AEC5@80864|Comamonadaceae 28216|Betaproteobacteria CO Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes yggX - - - - - - - - - - - Iron_traffic DYD2_k127_2866710_2 640081.Dsui_2814 1.697e-317 985.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,2KUJF@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N DYD2_k127_2866710_23 1266925.JHVX01000007_gene2290 2.767e-117 400.0 COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2VM3G@28216|Betaproteobacteria,372SC@32003|Nitrosomonadales 28216|Betaproteobacteria S CHAD - - - - - - - - - - - - CHAD,CYTH DYD2_k127_2866710_38 323848.Nmul_A0198 1.723e-48 178.0 COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,37363@32003|Nitrosomonadales 28216|Betaproteobacteria T Phosphoglycerate mutase family sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 DYD2_k127_2866710_11 1266925.JHVX01000003_gene693 4.355e-181 581.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,371PP@32003|Nitrosomonadales 28216|Betaproteobacteria FP Ppx GppA phosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA DYD2_k127_2866710_27 582744.Msip34_0165 4.965e-99 328.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,2KM7N@206350|Nitrosomonadales 206350|Nitrosomonadales P Plays a role in the regulation of phosphate uptake - - - ko:K02039 - - - - ko00000 - - - PhoU DYD2_k127_2866710_30 580332.Slit_2733 5.79e-94 315.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,44VEN@713636|Nitrosomonadales 28216|Betaproteobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A,Sugar-bind DYD2_k127_2866710_4 1163617.SCD_n00393 3.957e-242 756.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria 28216|Betaproteobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C DYD2_k127_2866710_17 1163617.SCD_n00396 5.864e-159 517.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria 28216|Betaproteobacteria M transglycosylase slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L DYD2_k127_2897551_2 395493.BegalDRAFT_2350 7.769e-77 268.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,460R1@72273|Thiotrichales 72273|Thiotrichales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 DYD2_k127_2897551_3 1123368.AUIS01000009_gene2457 2.758e-48 175.0 COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S8VM@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the thioredoxin family trxA3 - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD2_k127_2897551_0 543728.Vapar_5340 3.653e-189 600.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,4AA73@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD2_k127_2897551_1 1116472.MGMO_53c00610 2.224e-172 552.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XDNC@135618|Methylococcales 135618|Methylococcales EH synthase component I pabB - 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind DYD2_k127_2928665_24 1234364.AMSF01000072_gene1789 6.768e-53 192.0 COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,1S2HE@1236|Gammaproteobacteria,1X73Y@135614|Xanthomonadales 135614|Xanthomonadales S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short DYD2_k127_2928665_12 1123367.C666_08435 4.794e-134 434.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,2KVCI@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh DYD2_k127_2928665_23 1234364.AMSF01000005_gene743 1.562e-54 202.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,1RNSJ@1236|Gammaproteobacteria,1X6DN@135614|Xanthomonadales 135614|Xanthomonadales C Part of a membrane complex involved in electron transport ydgM - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 DYD2_k127_2928665_20 1163617.SCD_n02336 1.269e-75 266.0 COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria,2VIBK@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM peptidase M48 Ste24p - - - - - - - - - - - - Peptidase_M48 DYD2_k127_2928665_33 1223521.BBJX01000009_gene1196 9.291e-16 84.0 COG3103@1|root,COG3103@2|Bacteria,1N6AX@1224|Proteobacteria,2VVME@28216|Betaproteobacteria 28216|Betaproteobacteria T Bacterial SH3 domain - - - - - - - - - - - - SH3_3 DYD2_k127_2928665_18 62928.azo1435 1.565e-88 302.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,2KUZB@206389|Rhodocyclales 206389|Rhodocyclales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD DYD2_k127_2928665_32 472759.Nhal_0059 8.932e-17 83.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1X1FH@135613|Chromatiales 135613|Chromatiales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD2_k127_2928665_4 1123368.AUIS01000031_gene1420 6.197e-217 689.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,2NE68@225057|Acidithiobacillales 225057|Acidithiobacillales P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp DYD2_k127_2928665_11 1123368.AUIS01000031_gene1418 2.848e-134 436.0 COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,1T8C8@1236|Gammaproteobacteria,2NCKI@225057|Acidithiobacillales 225057|Acidithiobacillales S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE DYD2_k127_2928665_34 1123376.AUIU01000019_gene1271 5.948e-10 63.0 2EGXE@1|root,33APK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_2928665_6 1232683.ADIMK_0084 2.52e-212 677.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD2_k127_2928665_21 999541.bgla_1g06600 1.471e-69 240.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,1K1TA@119060|Burkholderiaceae 28216|Betaproteobacteria S Adenosyltransferase yvqK GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans DYD2_k127_2928665_25 1156919.QWC_27481 2.64e-52 194.0 COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2VQNP@28216|Betaproteobacteria,3T4G8@506|Alcaligenaceae 28216|Betaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD2_k127_2928665_28 420662.Mpe_A3548 9.096e-34 139.0 COG5343@1|root,COG5343@2|Bacteria,1N821@1224|Proteobacteria,2VSFF@28216|Betaproteobacteria,1KM8C@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Anti-sigma-K factor rskA - - - - - - - - - - - - RskA DYD2_k127_2928665_31 160488.PP_0090 4.593e-19 89.0 2EGJ5@1|root,33ABC@2|Bacteria,1NI51@1224|Proteobacteria,1SH35@1236|Gammaproteobacteria,1YVMJ@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Protein of unknown function (DUF1161) - - - - - - - - - - - - DUF1161 DYD2_k127_2928665_22 1095769.CAHF01000022_gene361 2.919e-68 239.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,2VZ0V@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_2928665_19 1163617.SCD_n02045 1.476e-79 276.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria 28216|Betaproteobacteria P Pfam Periplasmic binding protein btuF - - ko:K02016,ko:K06858 ko02010,map02010 M00240,M00241 - - ko00000,ko00001,ko00002,ko02000 3.A.1.13,3.A.1.14 - - Peripla_BP_2 DYD2_k127_2928665_29 887898.HMPREF0551_1669 8.649e-32 132.0 COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,2VX3A@28216|Betaproteobacteria 28216|Betaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding DYD2_k127_2928665_8 640081.Dsui_3444 2.77e-172 546.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,2KU9M@206389|Rhodocyclales 206389|Rhodocyclales E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 DYD2_k127_2928665_2 323848.Nmul_A1055 3.509e-239 750.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,372FQ@32003|Nitrosomonadales 28216|Betaproteobacteria S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD DYD2_k127_2928665_13 582744.Msip34_1247 4.665e-125 407.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,2KKUS@206350|Nitrosomonadales 206350|Nitrosomonadales S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase DYD2_k127_2928665_0 1163617.SCD_n01950 0.0 1160.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function - - - - - - - - - - - - AsmA_2,DUF3971 DYD2_k127_2928665_1 1163617.SCD_n01958 1.073e-308 970.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria 28216|Betaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE DYD2_k127_2928665_10 580332.Slit_2097 9.205e-136 446.0 COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2VHX9@28216|Betaproteobacteria 28216|Betaproteobacteria T PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.2 ko:K01769 ko00230,map00230 - R00434 RC00295 ko00000,ko00001,ko01000 - - - Guanylate_cyc DYD2_k127_2928665_9 582744.Msip34_2144 1.596e-157 504.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,2KKQW@206350|Nitrosomonadales 206350|Nitrosomonadales E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD2_k127_2928665_30 153948.NAL212_0854 9.335e-31 122.0 COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,373FJ@32003|Nitrosomonadales 28216|Betaproteobacteria S Zinc-finger domain - - - - - - - - - - - - zf-CHCC DYD2_k127_2928665_15 1485544.JQKP01000003_gene95 1.043e-111 371.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,44UZE@713636|Nitrosomonadales 28216|Betaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) rfaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD2_k127_2928665_27 497321.C664_10218 4.583e-38 148.0 COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2VU96@28216|Betaproteobacteria,2KWYZ@206389|Rhodocyclales 206389|Rhodocyclales S SnoaL-like domain - - - - - - - - - - - - SnoaL_3 DYD2_k127_2928665_3 1205680.CAKO01000026_gene4594 2.257e-231 725.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - ko:K13796 - - - - ko00000 - - - FAD_binding_2 DYD2_k127_2928665_16 172088.AUGA01000008_gene1089 3.756e-111 369.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,3JUUN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Class II Aldolase and Adducin N-terminal domain addA - - - - - - - - - - - Aldolase_II DYD2_k127_2928665_14 292415.Tbd_2137 3.703e-120 394.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria 28216|Betaproteobacteria S Alpha beta hydrolase - - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 DYD2_k127_2928665_5 1163617.SCD_n01965 1.576e-215 676.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria 28216|Betaproteobacteria G phosphoglucomutase phosphomannomutase alpha beta alpha domain II algC GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 ko:K01835,ko:K01840,ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114,M00549 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD2_k127_2928665_26 1183438.GKIL_0412 2.787e-52 189.0 COG3837@1|root,COG3837@2|Bacteria,1G7G2@1117|Cyanobacteria 1117|Cyanobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_2928665_17 580332.Slit_2518 5.545e-110 362.0 COG3021@1|root,COG3021@2|Bacteria 2|Bacteria S interspecies interaction between organisms - - - - - - - - - - - - Exo_endo_phos DYD2_k127_2928665_7 626418.bglu_1g22220 3.057e-194 617.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,1K06F@119060|Burkholderiaceae 28216|Betaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD2_k127_2951030_0 580332.Slit_2679 2.726e-222 707.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,44V3U@713636|Nitrosomonadales 28216|Betaproteobacteria V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K02021,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran DYD2_k127_2951030_1 1485544.JQKP01000002_gene1357 6.828e-106 353.0 COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,2WGMC@28216|Betaproteobacteria,44V6B@713636|Nitrosomonadales 28216|Betaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD2_k127_2976488_5 1183438.GKIL_1426 4.561e-09 58.0 COG2084@1|root,COG2084@2|Bacteria,1G34X@1117|Cyanobacteria 1117|Cyanobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 DYD2_k127_2976488_3 264198.Reut_A1098 1.965e-102 340.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,1KIFR@119060|Burkholderiaceae 28216|Betaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD2_k127_2976488_4 1075090.GOAMR_58_00330 4.574e-33 133.0 COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4GENK@85026|Gordoniaceae 201174|Actinobacteria S Pfam:Pyridox_oxidase - - - - - - - - - - - - Putative_PNPOx DYD2_k127_2976488_1 414996.IL38_08665 4.896e-135 437.0 COG0031@1|root,COG0031@2|Bacteria,2IEPQ@201174|Actinobacteria,407HA@622450|Actinopolysporales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_2976488_0 795666.MW7_3367 8.772e-165 524.0 COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2WEZU@28216|Betaproteobacteria,1KHY1@119060|Burkholderiaceae 28216|Betaproteobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase DYD2_k127_2976488_2 795666.MW7_3366 1.052e-122 396.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2VNNF@28216|Betaproteobacteria,1K5D0@119060|Burkholderiaceae 28216|Betaproteobacteria I Coenzyme A transferase - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD2_k127_2990427_29 2002.JOEQ01000015_gene5090 9.408e-15 81.0 COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria 201174|Actinobacteria CO Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - DYD2_k127_2990427_22 1041146.ATZB01000032_gene455 1.265e-44 166.0 COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,4BETD@82115|Rhizobiaceae 28211|Alphaproteobacteria S YHS domain - - - - - - - - - - - - YHS DYD2_k127_2990427_8 1054213.HMPREF9946_04909 7.848e-125 407.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TUVT@28211|Alphaproteobacteria,2JZE5@204441|Rhodospirillales 28211|Alphaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_2990427_15 1366050.N234_10390 1.32e-80 276.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_2990427_32 232721.Ajs_0462 5.207e-10 62.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_2990427_1 76114.ebA664 4.175e-266 841.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,2KUX1@206389|Rhodocyclales 206389|Rhodocyclales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV DYD2_k127_2990427_0 243365.CV_1113 2.851e-275 863.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,2KPMW@206351|Neisseriales 206351|Neisseriales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD2_k127_2990427_12 1380394.JADL01000013_gene698 4.042e-87 294.0 COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U59W@28211|Alphaproteobacteria,2JSC8@204441|Rhodospirillales 204441|Rhodospirillales C Nitroreductase family - - - - - - - - - - - - Nitroreductase DYD2_k127_2990427_14 330214.NIDE3374 8.526e-82 286.0 28I4Y@1|root,2Z88D@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_2990427_19 488538.SAR116_0921 4.267e-68 240.0 COG1028@1|root,COG1028@2|Bacteria 488538.SAR116_0921|- IQ oxidoreductase activity, acting on CH-OH group of donors - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - - DYD2_k127_2990427_31 452662.SJA_C1-19790 1.79e-11 68.0 COG4221@1|root,COG4221@2|Bacteria,1NTNU@1224|Proteobacteria,2TYAI@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short DYD2_k127_2990427_20 368408.Tpen_1165 3.655e-64 228.0 COG3839@1|root,arCOG00175@2157|Archaea,2XPUC@28889|Crenarchaeota 28889|Crenarchaeota G PFAM ABC transporter related - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 DYD2_k127_2990427_26 1249627.D779_0780 7.683e-25 115.0 COG0500@1|root,COG2226@2|Bacteria,1N3VV@1224|Proteobacteria,1SCTZ@1236|Gammaproteobacteria,1WZXH@135613|Chromatiales 135613|Chromatiales Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - - DYD2_k127_2990427_18 1108045.GORHZ_084_00430 4.526e-71 249.0 COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4GEP0@85026|Gordoniaceae 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD2_k127_2990427_24 1366050.N234_32650 5.881e-34 137.0 COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,1KD7R@119060|Burkholderiaceae 28216|Betaproteobacteria T Universal stress protein family - - - - - - - - - - - - Usp DYD2_k127_2990427_7 595494.Tola_1866 7.596e-143 468.0 COG3591@1|root,COG3591@2|Bacteria,1R8XR@1224|Proteobacteria,1RZT2@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the peptidase S1B family - - - - - - - - - - - - - DYD2_k127_2990427_25 622637.KE124774_gene4013 1.681e-26 115.0 2ER8M@1|root,315A2@2|Bacteria,1ND1P@1224|Proteobacteria,2UHCM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_2990427_30 384765.SIAM614_29791 3.551e-12 70.0 COG1359@1|root,COG1359@2|Bacteria,1N98F@1224|Proteobacteria,2UFXS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM DYD2_k127_2990427_2 1144319.PMI16_03835 6.324e-238 746.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,473DD@75682|Oxalobacteraceae 28216|Betaproteobacteria E GMC oxidoreductase betA - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N DYD2_k127_2990427_28 1283300.ATXB01000001_gene1949 3.322e-16 85.0 COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,1SAW8@1236|Gammaproteobacteria,1XGQM@135618|Methylococcales 135618|Methylococcales T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR DYD2_k127_2990427_23 43759.JNWK01000005_gene1016 1.549e-40 158.0 COG1853@1|root,COG1853@2|Bacteria,2GK9V@201174|Actinobacteria 201174|Actinobacteria H flavin reductase - - - - - - - - - - - - Flavin_Reduct DYD2_k127_2990427_4 1002672.SAR11G3_01300 1.262e-168 541.0 COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2UBG9@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD2_k127_2990427_10 765698.Mesci_1066 2.313e-108 359.0 COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,43I60@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G gluconolactonase MA20_13995 - 3.1.1.17 ko:K01053,ko:K14274 ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02427,R02933,R03751 RC00537,RC00713,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Isochorismatase,SGL DYD2_k127_2990427_3 709797.CSIRO_0066 4.081e-224 707.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,3JVAX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_2990427_6 1054213.HMPREF9946_03253 1.426e-147 473.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,2JS0P@204441|Rhodospirillales 204441|Rhodospirillales Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD2_k127_2990427_16 1366050.N234_10650 8.806e-80 278.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM0F@28216|Betaproteobacteria 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_2990427_9 1298867.AUES01000001_gene1607 1.279e-119 396.0 COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,3JQU4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NHL repeat - - - - - - - - - - - - NHL DYD2_k127_2990427_17 1121924.ATWH01000007_gene2181 3.388e-78 272.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Abhydrolase_6,DLH,Hydrolase_4 DYD2_k127_2990427_13 1366050.N234_22440 1.892e-86 296.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP82@28216|Betaproteobacteria,1KD4A@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_2990427_5 1231391.AMZF01000037_gene583 1.692e-152 488.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VI5X@28216|Betaproteobacteria,3T6F3@506|Alcaligenaceae 28216|Betaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase DYD2_k127_2990427_11 296591.Bpro_3022 3.745e-98 330.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VMVX@28216|Betaproteobacteria,4A9VB@80864|Comamonadaceae 28216|Betaproteobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_2990427_27 314256.OG2516_14900 1.125e-24 108.0 COG2050@1|root,COG2050@2|Bacteria,1PP3J@1224|Proteobacteria,2U5E4@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q protein possibly involved in aromatic compounds catabolism MA20_28520 - - - - - - - - - - - 4HBT DYD2_k127_3023155_18 1144319.PMI16_01485 6.078e-37 145.0 292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,2VRDD@28216|Betaproteobacteria,472PX@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function (DUF3047) - - - - - - - - - - - - DUF3047 DYD2_k127_3023155_17 1000565.METUNv1_01713 2.571e-37 147.0 COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2VUA6@28216|Betaproteobacteria,2KZ1N@206389|Rhodocyclales 206389|Rhodocyclales L Staphylococcal nuclease homologues - - - - - - - - - - - - SNase DYD2_k127_3023155_4 1163617.SCD_n01904 2.454e-159 516.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria 28216|Betaproteobacteria M N-Acetylmuramoyl-L-alanine amidase amiC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3 DYD2_k127_3023155_16 323848.Nmul_A2531 5.38e-47 187.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,3735C@32003|Nitrosomonadales 28216|Betaproteobacteria S Threonylcarbamoyl adenosine biosynthesis protein TsaE yjeE - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE DYD2_k127_3023155_2 1123368.AUIS01000006_gene624 1.311e-170 542.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 DYD2_k127_3023155_7 69395.JQLZ01000007_gene1721 3.333e-89 305.0 COG0346@1|root,COG0346@2|Bacteria,1MUBT@1224|Proteobacteria,2VG62@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD2_k127_3023155_8 1157708.KB907472_gene1318 5.24e-82 284.0 COG3181@1|root,COG3181@2|Bacteria,1R81N@1224|Proteobacteria,2VMV6@28216|Betaproteobacteria,4ABW0@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_3023155_22 1123288.SOV_3c04950 3.712e-14 84.0 COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4H3ME@909932|Negativicutes 909932|Negativicutes G Bacterial extracellular solute-binding protein, family 7 dctP - - ko:K21395 - - - - ko00000,ko02000 2.A.56.1 - - DctP DYD2_k127_3023155_23 765912.Thimo_2532 6.632e-07 58.0 COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,1RZ8E@1236|Gammaproteobacteria,1WY1H@135613|Chromatiales 135613|Chromatiales G PFAM Tripartite ATP-independent periplasmic - - - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ DYD2_k127_3023155_9 62928.azo0921 9.869e-78 276.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,2KY3Z@206389|Rhodocyclales 206389|Rhodocyclales G TRAP-type C4-dicarboxylate transport system, large permease - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM DYD2_k127_3023155_20 1300345.LF41_1319 4.646e-33 133.0 COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales 135614|Xanthomonadales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 DYD2_k127_3023155_1 1238182.C882_4345 3.388e-179 583.0 COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,2TXK8@28211|Alphaproteobacteria,2JVHU@204441|Rhodospirillales 204441|Rhodospirillales E Sodium:solute symporter family - - - - - - - - - - - - SSF DYD2_k127_3023155_11 314285.KT71_01925 7.317e-74 252.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1J998@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C SelR domain - - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR,TAT_signal DYD2_k127_3023155_0 316056.RPC_1074 4.253e-180 570.0 COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria,3JRM3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I acetyl-coa acetyltransferase - - - - - - - - - - - - Thiolase_C DYD2_k127_3023155_19 316056.RPC_1073 2.676e-34 138.0 COG1545@1|root,COG1545@2|Bacteria,1N2C8@1224|Proteobacteria,2U8C7@28211|Alphaproteobacteria,3K4WC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Rubredoxin-like zinc ribbon domain (DUF35_N) - - - ko:K07068 - - - - ko00000 - - - DUF35_N,OB_aCoA_assoc DYD2_k127_3023155_14 266265.Bxe_C0269 3.58e-70 246.0 COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2W1W1@28216|Betaproteobacteria,1KHVV@119060|Burkholderiaceae 28216|Betaproteobacteria I Enoyl-CoA hydratase/isomerase - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 DYD2_k127_3023155_3 1123501.KB902294_gene3527 6.467e-168 552.0 COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1042 Acyl-CoA synthetase (NDP forming) - - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD2_k127_3023155_5 864073.HFRIS_001549 3.997e-121 395.0 COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2VJQ2@28216|Betaproteobacteria 28216|Betaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short,adh_short_C2 DYD2_k127_3023155_6 331869.BAL199_13528 7.744e-103 342.0 COG2030@1|root,COG2030@2|Bacteria,1MUR2@1224|Proteobacteria,2TUM7@28211|Alphaproteobacteria 28211|Alphaproteobacteria I dehydratase - - - - - - - - - - - - MaoC_dehydrat_N,MaoC_dehydratas DYD2_k127_3023155_13 1175306.GWL_44870 2.028e-70 242.0 COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2VQDH@28216|Betaproteobacteria,4736X@75682|Oxalobacteraceae 28216|Betaproteobacteria O Redoxin ahp1 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - Redoxin DYD2_k127_3023155_12 243233.MCA0141 2.534e-71 247.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,1XF3U@135618|Methylococcales 135618|Methylococcales S PFAM Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP DYD2_k127_3023155_10 1173028.ANKO01000153_gene5369 2.644e-74 262.0 COG3386@1|root,COG3386@2|Bacteria,1G05C@1117|Cyanobacteria,1H9TR@1150|Oscillatoriales 1117|Cyanobacteria G PFAM SMP-30 Gluconolaconase LRE-like region - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD2_k127_3023155_21 886293.Sinac_7488 2.379e-31 134.0 COG3386@1|root,COG3386@2|Bacteria,2IZFH@203682|Planctomycetes 203682|Planctomycetes G SMP-30/Gluconolaconase/LRE-like region - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD2_k127_3023155_15 1120949.KB903357_gene4895 8.839e-67 233.0 COG0028@1|root,COG0028@2|Bacteria,2I9V6@201174|Actinobacteria 201174|Actinobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_3097715_7 580332.Slit_1063 2.991e-193 613.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,44VBG@713636|Nitrosomonadales 28216|Betaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD2_k127_3097715_22 640081.Dsui_3058 4.973e-101 336.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,2KV7R@206389|Rhodocyclales 206389|Rhodocyclales H dihydropteroate synthase dhpS - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind DYD2_k127_3097715_1 1163617.SCD_n00924 0.0 1068.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria 28216|Betaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD2_k127_3097715_28 1485544.JQKP01000008_gene1768 1.338e-70 244.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,44UZM@713636|Nitrosomonadales 28216|Betaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ DYD2_k127_3097715_41 1000565.METUNv1_00378 1.161e-25 115.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,2KXBI@206389|Rhodocyclales 206389|Rhodocyclales J RNA-binding protein containing KH domain possibly ribosomal protein - - - - - - - - - - - - CRS1_YhbY DYD2_k127_3097715_26 85643.Tmz1t_1733 2.161e-77 261.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,2KUSV@206389|Rhodocyclales 206389|Rhodocyclales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N DYD2_k127_3097715_0 1163617.SCD_n00919 0.0 1749.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria 28216|Betaproteobacteria F Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS DYD2_k127_3097715_9 1122236.KB905142_gene492 4.375e-180 571.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,2KMEN@206350|Nitrosomonadales 206350|Nitrosomonadales EF TIGRFAM carbamoyl-phosphate synthase, small subunit carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase DYD2_k127_3097715_19 1163617.SCD_n00917 3.125e-110 362.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria 28216|Betaproteobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N DYD2_k127_3097715_40 1163617.SCD_n00916 3.28e-26 118.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA DYD2_k127_3097715_29 1288494.EBAPG3_4330 7.772e-67 233.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,37316@32003|Nitrosomonadales 28216|Betaproteobacteria K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR DYD2_k127_3097715_37 1205680.CAKO01000035_gene237 1.016e-37 147.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity iolI - 1.13.11.27,5.3.99.11 ko:K00457,ko:K06606 ko00130,ko00350,ko00360,ko00562,ko01100,ko01120,map00130,map00350,map00360,map00562,map01100,map01120 M00044 R01372,R02521,R09952 RC00505,RC00738,RC01513 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AP_endonuc_2 DYD2_k127_3097715_34 1279009.ADICEAN_00034 1.44e-56 204.0 2C8PG@1|root,32RMK@2|Bacteria,4P5DF@976|Bacteroidetes,47VYD@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3097715_12 264198.Reut_B4564 5.565e-154 496.0 COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2VKB0@28216|Betaproteobacteria,1K405@119060|Burkholderiaceae 28216|Betaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD2_k127_3097715_8 1163617.SCD_n00912 1.868e-183 589.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria 28216|Betaproteobacteria L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N DYD2_k127_3097715_20 1288494.EBAPG3_27470 1.245e-107 357.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria,372GT@32003|Nitrosomonadales 28216|Betaproteobacteria F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase DYD2_k127_3097715_15 1288494.EBAPG3_27490 1.555e-143 462.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,372A2@32003|Nitrosomonadales 28216|Betaproteobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg DYD2_k127_3097715_18 1120999.JONM01000008_gene2007 3.915e-129 422.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,2KPE7@206351|Neisseriales 206351|Neisseriales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase DYD2_k127_3097715_35 1158762.KB898038_gene1822 8.163e-43 165.0 COG5592@1|root,COG5592@2|Bacteria,1NWD3@1224|Proteobacteria,1SPHH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Uncharacterized conserved protein (DUF2249) - - - - - - - - - - - - DUF2249,Hemerythrin DYD2_k127_3097715_31 1163617.SCD_n00903 1.306e-63 224.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria 28216|Betaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE DYD2_k127_3097715_2 1121004.ATVC01000087_gene305 2.777e-317 981.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KPV9@206351|Neisseriales 206351|Neisseriales O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD2_k127_3097715_6 1236959.BAMT01000001_gene1002 3.538e-195 613.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KKPJ@206350|Nitrosomonadales 206350|Nitrosomonadales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD2_k127_3097715_32 1207063.P24_12647 4.186e-63 225.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,2JSRE@204441|Rhodospirillales 204441|Rhodospirillales O Glutathione S-transferase - - - - - - - - - - - - GST_C_2,GST_N_3 DYD2_k127_3097715_3 331869.BAL199_24109 1.408e-268 839.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,4BPZA@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_3097715_33 1002672.SAR11G3_01300 4.536e-58 218.0 COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2UBG9@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD2_k127_3097715_38 331869.BAL199_20860 8.761e-33 143.0 COG4122@1|root,COG4122@2|Bacteria,1NG6W@1224|Proteobacteria,2UM77@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Macrocin-O-methyltransferase (TylF) - - - ko:K05303 - - - - ko00000,ko01000 - - - TylF DYD2_k127_3097715_16 1123393.KB891333_gene2602 1.803e-131 451.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria 28216|Betaproteobacteria O TPR repeat-containing protein - - - - - - - - - - - - Glyco_transf_41,MethyTransf_Reg,SEC-C,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 DYD2_k127_3097715_10 1049564.TevJSym_af00670 1.596e-164 527.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1J50C@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Na+ dependent nucleoside transporter N-terminus nupX GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N DYD2_k127_3097715_5 159087.Daro_0919 8.129e-219 687.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,2KUCB@206389|Rhodocyclales 206389|Rhodocyclales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g DYD2_k127_3097715_23 1163617.SCD_n00897 1.35e-89 308.0 COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria 28216|Betaproteobacteria NU PFAM TPR repeat-containing protein - - - - - - - - - - - - DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8 DYD2_k127_3097715_17 1163617.SCD_n00896 1.483e-129 427.0 COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria 28216|Betaproteobacteria S ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD DYD2_k127_3097715_30 1121004.ATVC01000049_gene926 1.495e-64 229.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,2KQYA@206351|Neisseriales 206351|Neisseriales M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA - 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase DYD2_k127_3097715_27 640081.Dsui_3088 1.007e-72 256.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,2KW4W@206389|Rhodocyclales 206389|Rhodocyclales O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase DYD2_k127_3097715_25 1163617.SCD_n00893 3.98e-82 284.0 COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria 28216|Betaproteobacteria S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 DYD2_k127_3097715_24 338969.Rfer_3416 4.1e-89 300.0 COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2VQPA@28216|Betaproteobacteria 28216|Betaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 DYD2_k127_3097715_11 1286093.C266_18116 9.032e-163 521.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,1KIDZ@119060|Burkholderiaceae 28216|Betaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - 2.5.1.48 ko:K01739,ko:K10764 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP DYD2_k127_3097715_4 323848.Nmul_A1906 5.007e-247 770.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,3723J@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran DYD2_k127_3097715_36 1266925.JHVX01000009_gene99 7.253e-42 163.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,3739Y@32003|Nitrosomonadales 28216|Betaproteobacteria S Colicin V production cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V DYD2_k127_3097715_39 1288494.EBAPG3_25380 6.653e-27 117.0 COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,373EA@32003|Nitrosomonadales 28216|Betaproteobacteria S Sporulation related domain dedD - - ko:K03749 - - - - ko00000 - - - SPOR DYD2_k127_3097715_13 395494.Galf_0502 2.029e-150 487.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,44V34@713636|Nitrosomonadales 28216|Betaproteobacteria H PFAM Mur ligase middle domain protein folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M DYD2_k127_3097715_14 1163617.SCD_n00885 1.017e-144 464.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria 28216|Betaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD2_k127_3097715_21 1366050.N234_14820 9.349e-105 347.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,1K2CE@119060|Burkholderiaceae 28216|Betaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA DYD2_k127_310618_12 391615.ABSJ01000026_gene121 3.122e-83 287.0 2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1J8X1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - - DYD2_k127_310618_3 1121396.KB892946_gene2947 1.384e-137 451.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,2MKZD@213118|Desulfobacterales 28221|Deltaproteobacteria C PFAM Alcohol dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD2_k127_310618_6 94624.Bpet3680 7.847e-126 419.0 COG0318@1|root,COG0318@2|Bacteria,1R3FB@1224|Proteobacteria,2W0RG@28216|Betaproteobacteria,3T27X@506|Alcaligenaceae 28216|Betaproteobacteria IQ Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C DYD2_k127_310618_7 331869.BAL199_11871 1.043e-113 374.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_310618_22 1151126.AQYI01000007_gene2179 3.149e-14 83.0 COG3971@1|root,COG3971@2|Bacteria,2GPBI@201174|Actinobacteria,4FK5C@85023|Microbacteriaceae 201174|Actinobacteria Q Fumarylacetoacetate (FAA) hydrolase family hpaH - - ko:K02509 ko00350,ko01120,map00350,map01120 - R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 - - - FAA_hydrolase DYD2_k127_310618_20 311403.Arad_7196 9.686e-18 92.0 COG0662@1|root,COG0662@2|Bacteria,1P7SH@1224|Proteobacteria,2UW18@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_310618_13 485913.Krac_9361 3.439e-75 264.0 COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi 200795|Chloroflexi C PFAM 6-phosphogluconate dehydrogenase NAD-binding - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD2_k127_310618_16 1123388.AQWU01000069_gene237 1.191e-42 163.0 COG2030@1|root,COG2030@2|Bacteria,1WJC4@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydratas DYD2_k127_310618_8 644966.Tmar_1575 2.687e-107 360.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,3WD6V@538999|Clostridiales incertae sedis 186801|Clostridia C acyl-CoA transferase carnitine dehydratase - - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 DYD2_k127_310618_9 1054213.HMPREF9946_02427 2.916e-100 342.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TVS9@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_310618_15 767817.Desgi_1296 3.716e-46 179.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,24AIH@186801|Clostridia,260C4@186807|Peptococcaceae 186801|Clostridia G Belongs to the HpcH HpaI aldolase family - - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI DYD2_k127_310618_18 1042209.HK44_007705 1.41e-32 137.0 COG4126@1|root,COG4126@2|Bacteria,1PN0M@1224|Proteobacteria,1SUB2@1236|Gammaproteobacteria 1236|Gammaproteobacteria E flavin adenine dinucleotide binding - - - - - - - - - - - - - DYD2_k127_310618_10 693986.MOC_0372 2.961e-97 323.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2TUZ8@28211|Alphaproteobacteria,1JWCJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria I Coenzyme A transferase - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD2_k127_310618_14 693986.MOC_0373 1.299e-62 218.0 COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2TVMU@28211|Alphaproteobacteria,1JWHD@119045|Methylobacteriaceae 28211|Alphaproteobacteria I Coenzyme A transferase - - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD2_k127_310618_17 1216976.AX27061_4373 1.502e-42 158.0 COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2VK8V@28216|Betaproteobacteria,3T20V@506|Alcaligenaceae 28216|Betaproteobacteria I Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit gctA - 2.8.3.12,2.8.3.5 ko:K01028,ko:K01039 ko00072,ko00280,ko00643,ko00650,ko01120,map00072,map00280,map00643,map00650,map01120 - R00410,R04000,R05509 RC00012,RC00014,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD2_k127_310618_5 257310.BB0681 6.816e-134 439.0 COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2W02V@28216|Betaproteobacteria 28216|Betaproteobacteria L LVIVD repeat - - - - - - - - - - - - LVIVD DYD2_k127_310618_2 1111728.ATYS01000060_gene2887 1.528e-182 583.0 COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,1RS00@1236|Gammaproteobacteria 1236|Gammaproteobacteria F 3-carboxy-cis,cis-muconate cycloisomerase - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 DYD2_k127_310618_4 1038859.AXAU01000013_gene6552 2.272e-135 439.0 COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2TWC9@28211|Alphaproteobacteria,3JVP3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_310618_19 397945.Aave_1069 1.432e-26 115.0 29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VT23@28216|Betaproteobacteria,4AE1W@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD2_k127_310618_1 1157708.KB907455_gene3218 4.058e-208 659.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AGCN@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctA family tctA4 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_310618_11 266265.Bxe_B2346 7.579e-92 316.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VPM0@28216|Betaproteobacteria,1K94Z@119060|Burkholderiaceae 28216|Betaproteobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - - - - - - - - - - 2-Hacid_dh_C DYD2_k127_310618_0 1038858.AXBA01000018_gene1238 3.68e-266 830.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the UbiD family - - 4.1.1.98 ko:K03182,ko:K16874 ko00130,ko00365,ko01100,ko01110,ko01120,map00130,map00365,map01100,map01110,map01120 M00117 R04985,R04986,R10213 RC00391,RC03086 ko00000,ko00001,ko00002,ko01000 - - - UbiD DYD2_k127_310618_21 1071679.BG57_07070 2.986e-17 82.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,1K08A@119060|Burkholderiaceae 28216|Betaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186,ko:K16875 ko00130,ko00365,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R10213,R11225 RC00391,RC00814,RC03086,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein DYD2_k127_3119071_3 1163617.SCD_n00047 7.99e-32 127.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria 28216|Betaproteobacteria F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH DYD2_k127_3119071_4 1163617.SCD_n00046 1.13e-29 133.0 2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2782) - - - - - - - - - - - - DUF2782 DYD2_k127_3119071_0 1031711.RSPO_c01200 0.0 1165.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,1K0FY@119060|Burkholderiaceae 28216|Betaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 DYD2_k127_3119071_2 582744.Msip34_1757 4.284e-72 250.0 2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,2KKNU@206350|Nitrosomonadales 206350|Nitrosomonadales S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 DYD2_k127_3119071_1 323848.Nmul_A1987 2.328e-138 442.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,371U2@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM DYD2_k127_3126435_0 1163617.SCD_n00855 0.0 1069.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria 28216|Betaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD2_k127_3126435_1 396588.Tgr7_2455 1.526e-164 535.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales 135613|Chromatiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD2_k127_3126435_2 1163617.SCD_n00058 1.057e-71 248.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD2_k127_3126435_3 323848.Nmul_A0361 4.063e-38 145.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,373F4@32003|Nitrosomonadales 28216|Betaproteobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD2_k127_3131983_18 1123393.KB891330_gene879 1.579e-39 150.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,1KS68@119069|Hydrogenophilales 119069|Hydrogenophilales S Patatin-like phospholipase - - - - - - - - - - - - Patatin DYD2_k127_3131983_4 1288494.EBAPG3_1920 3.315e-173 552.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria,371WQ@32003|Nitrosomonadales 28216|Betaproteobacteria C MOFRL family ttuD2 - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL DYD2_k127_3131983_0 323848.Nmul_A2229 0.0 1505.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,3726S@32003|Nitrosomonadales 28216|Betaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD2_k127_3131983_5 1266925.JHVX01000006_gene2240 2.153e-158 512.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,372X1@32003|Nitrosomonadales 28216|Betaproteobacteria EGP Sugar (and other) transporter yajR - - - - - - - - - - - MFS_1,Sugar_tr DYD2_k127_3131983_15 882378.RBRH_02121 4.977e-61 213.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,1K2Q6@119060|Burkholderiaceae 28216|Betaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB DYD2_k127_3131983_17 1123368.AUIS01000001_gene1864 1.019e-52 206.0 COG1315@1|root,COG1315@2|Bacteria 2|Bacteria L Flagellar Assembly Protein A - - - ko:K09749 - - - - ko00000 - - - FapA DYD2_k127_3131983_20 1288494.EBAPG3_10720 3.894e-28 116.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,373IS@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 DYD2_k127_3131983_13 1266925.JHVX01000003_gene530 8.251e-87 291.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,372E4@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 DYD2_k127_3131983_1 1288494.EBAPG3_10740 2.157e-295 915.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,371U3@32003|Nitrosomonadales 28216|Betaproteobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon DYD2_k127_3131983_19 1896.JOAU01000013_gene1955 1.365e-32 131.0 COG4290@1|root,COG4290@2|Bacteria,2IHPV@201174|Actinobacteria 201174|Actinobacteria F Ribonuclease - - 3.1.27.3 ko:K01167 - - - - ko00000,ko01000,ko03016,ko03019 - - - Ribonuclease DYD2_k127_3131983_21 748247.AZKH_3580 2.507e-21 98.0 COG2732@1|root,COG2732@2|Bacteria,1NB8S@1224|Proteobacteria,2WE8N@28216|Betaproteobacteria,2KX6I@206389|Rhodocyclales 206389|Rhodocyclales K Barstar (barnase inhibitor) - - - - - - - - - - - - Barstar DYD2_k127_3131983_16 1217718.ALOU01000002_gene4724 2.99e-59 210.0 COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,1K6ZD@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM NUDIX hydrolase ntpA - 3.6.1.67 ko:K08310 ko00790,map00790 M00126 R04638 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NUDIX DYD2_k127_3131983_3 323848.Nmul_A0605 3.982e-193 607.0 COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,371UG@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA DYD2_k127_3131983_8 335283.Neut_2298 1.958e-108 357.0 COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,372S8@32003|Nitrosomonadales 28216|Betaproteobacteria L PFAM Endonuclease exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos DYD2_k127_3131983_6 640081.Dsui_1041 1.23e-137 447.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,2KUFP@206389|Rhodocyclales 206389|Rhodocyclales I Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol clsB - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD2_k127_3131983_2 522306.CAP2UW1_3466 7.088e-239 753.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,1KQEA@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria V ABC transporter transmembrane region atm1 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD2_k127_3131983_7 1163617.SCD_n02307 7.03e-112 378.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGRW@28216|Betaproteobacteria 28216|Betaproteobacteria T histidine kinase HAMP region domain protein - - 2.7.13.3 ko:K07649 ko02020,map02020 M00457 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA DYD2_k127_3131983_14 580332.Slit_2492 3.632e-86 293.0 COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,44WD1@713636|Nitrosomonadales 28216|Betaproteobacteria K Two component transcriptional regulator, winged helix family basR_3 - - ko:K02483,ko:K07666,ko:K07774 ko02020,ko02024,map02020,map02024 M00453,M00457 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD2_k127_3131983_12 1288494.EBAPG3_1530 2.228e-88 300.0 COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,371XF@32003|Nitrosomonadales 28216|Betaproteobacteria M Beta-lactamase enzyme family pbpG - - ko:K07262 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S11 DYD2_k127_3131983_9 323261.Noc_2028 2.022e-107 357.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1WVVH@135613|Chromatiales 135613|Chromatiales S Methyltransferase - - 2.1.1.44 ko:K18911 ko00340,map00340 - R01169 RC00003,RC02308 ko00000,ko00001,ko01000 - - - Methyltransf_33 DYD2_k127_3131983_10 1231391.AMZF01000094_gene118 8.587e-91 312.0 COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria 28216|Betaproteobacteria EGP major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_3131983_11 671143.DAMO_0872 3.762e-89 302.0 COG2267@1|root,COG2267@2|Bacteria,2NRR1@2323|unclassified Bacteria 2|Bacteria I Alpha/beta hydrolase family - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 DYD2_k127_3131983_22 292415.Tbd_0092 4.639e-17 81.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,1KRSD@119069|Hydrogenophilales 119069|Hydrogenophilales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD2_k127_3141015_7 1288494.EBAPG3_21670 5.288e-54 191.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,371NY@32003|Nitrosomonadales 28216|Betaproteobacteria D Peptidase family M23 envC - - - - - - - - - - - Peptidase_M23 DYD2_k127_3141015_0 1163617.SCD_n02700 1.076e-201 637.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 DYD2_k127_3141015_4 1163617.SCD_n02701 7.328e-100 344.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria 28216|Betaproteobacteria H PFAM UBA THIF-type NAD FAD binding protein thiF - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF DYD2_k127_3141015_6 1163617.SCD_n02703 9.124e-81 273.0 COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria 28216|Betaproteobacteria K PFAM regulatory protein TetR slmA - - ko:K05501 - - - - ko00000,ko03000,ko03036 - - - TetR_N DYD2_k127_3141015_5 580332.Slit_0736 5.807e-88 294.0 COG0637@1|root,COG0637@2|Bacteria,1QTWD@1224|Proteobacteria,2VNTW@28216|Betaproteobacteria,44UZ1@713636|Nitrosomonadales 28216|Betaproteobacteria S HAD-superfamily hydrolase, subfamily IA, variant 3 - - - ko:K07025 - - - - ko00000 - - - HAD_2 DYD2_k127_3141015_1 1131553.JIBI01000002_gene1824 6.013e-147 469.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,3729E@32003|Nitrosomonadales 28216|Betaproteobacteria F Belongs to the acetylglutamate kinase family. ArgB subfamily argB - 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD2_k127_3141015_8 580332.Slit_0734 1.26e-47 175.0 COG0071@1|root,COG0071@2|Bacteria,1PV6Z@1224|Proteobacteria,2WA7J@28216|Betaproteobacteria,44WMZ@713636|Nitrosomonadales 28216|Betaproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD2_k127_3141015_2 323848.Nmul_A1991 2.032e-144 467.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,3721U@32003|Nitrosomonadales 28216|Betaproteobacteria M Belongs to the peptidase S11 family dacC - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 DYD2_k127_3141015_3 1163617.SCD_n00104 1.821e-117 384.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria 28216|Betaproteobacteria EH Aminotransferase class IV dat - 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 DYD2_k127_3141015_9 580332.Slit_0724 2.226e-29 122.0 COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,44W1W@713636|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF493) ybeD - - ko:K09158 - - - - ko00000 - - - DUF493 DYD2_k127_3159553_8 266265.Bxe_B2353 4.284e-103 340.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VQCJ@28216|Betaproteobacteria,1K1CQ@119060|Burkholderiaceae 28216|Betaproteobacteria H Belongs to the UbiD family - - - - - - - - - - - - UbiD DYD2_k127_3159553_13 296591.Bpro_0284 6.388e-80 280.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_3159553_2 795666.MW7_3341 5.339e-140 456.0 COG2080@1|root,COG3427@1|root,COG2080@2|Bacteria,COG3427@2|Bacteria,1MXN3@1224|Proteobacteria,2VTK5@28216|Betaproteobacteria,1K6RG@119060|Burkholderiaceae 28216|Betaproteobacteria C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - COXG,Fer2,Fer2_2 DYD2_k127_3159553_7 795666.MW7_3340 7.618e-107 358.0 COG1319@1|root,COG1319@2|Bacteria,1N4RF@1224|Proteobacteria,2W270@28216|Betaproteobacteria,1K5PZ@119060|Burkholderiaceae 28216|Betaproteobacteria C FAD binding domain in molybdopterin dehydrogenase - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - FAD_binding_5 DYD2_k127_3159553_0 639283.Snov_4237 0.0 1245.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3EY29@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_3159553_12 795666.MW7_3338 6.996e-84 293.0 COG2188@1|root,COG2188@2|Bacteria,1MVPT@1224|Proteobacteria,2VP7X@28216|Betaproteobacteria,1K99Q@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA DYD2_k127_3159553_3 795666.MW7_3337 4.403e-128 416.0 COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2VNJE@28216|Betaproteobacteria,1K05Q@119060|Burkholderiaceae 28216|Betaproteobacteria E Allophanate hydrolase kipA - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - CT_A_B DYD2_k127_3159553_10 795666.MW7_3336 1.102e-96 321.0 COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,2VQQM@28216|Betaproteobacteria,1K2IY@119060|Burkholderiaceae 28216|Betaproteobacteria E Allophanate hydrolase, subunit 1 kipI - - - - - - - - - - - CT_C_D DYD2_k127_3159553_5 795666.MW7_3335 1.064e-123 402.0 COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2VKKP@28216|Betaproteobacteria,1K64E@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the UPF0271 (lamB) family - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF DYD2_k127_3159553_11 795666.MW7_3334 6.36e-88 298.0 COG2085@1|root,COG2085@2|Bacteria,1MXS0@1224|Proteobacteria,2VRQ2@28216|Betaproteobacteria,1K9V6@119060|Burkholderiaceae 28216|Betaproteobacteria S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD2_k127_3159553_6 795666.MW7_3333 4.648e-108 358.0 COG1478@1|root,COG1478@2|Bacteria,1PQHN@1224|Proteobacteria,2VS0K@28216|Betaproteobacteria,1K7I5@119060|Burkholderiaceae 28216|Betaproteobacteria S F420-0:Gamma-glutamyl ligase - - 6.3.2.31,6.3.2.34 ko:K12234 ko00680,ko01120,map00680,map01120 M00378 R09399,R09400 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000 - - - F420_ligase DYD2_k127_3159553_4 795666.MW7_3332 2.643e-127 417.0 COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria,2VMUY@28216|Betaproteobacteria,1K5SP@119060|Burkholderiaceae 28216|Betaproteobacteria S Uncharacterised protein family UPF0052 - - 2.7.8.28 ko:K11212 ko00680,ko01120,map00680,map01120 M00378 R09398 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - UPF0052 DYD2_k127_3159553_1 795666.MW7_3330 0.0 1179.0 COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,2VZW4@28216|Betaproteobacteria,1K2DF@119060|Burkholderiaceae 28216|Betaproteobacteria H PFAM Radical SAM - - 2.5.1.77 ko:K11779 ko00680,ko01120,map00680,map01120 M00378 R09396 RC01381,RC03002,RC03007 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM DYD2_k127_3159553_9 1163617.SCD_n01875 3.624e-99 329.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria 28216|Betaproteobacteria L DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon DYD2_k127_3183473_12 1163617.SCD_n00874 1.005e-102 338.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria 28216|Betaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD2_k127_3183473_2 323848.Nmul_A1921 1.232e-236 738.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,372FS@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase DYD2_k127_3183473_10 1266925.JHVX01000009_gene112 4.491e-111 371.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,372M4@32003|Nitrosomonadales 28216|Betaproteobacteria EGP Nucleoside H+ symporter hcaT - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like DYD2_k127_3183473_4 1288494.EBAPG3_25860 4.656e-195 614.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,37234@32003|Nitrosomonadales 28216|Betaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt DYD2_k127_3183473_1 748247.AZKH_0280 1.438e-255 802.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,2KV3W@206389|Rhodocyclales 206389|Rhodocyclales I Transmembrane secretion effector - - - - - - - - - - - - Acyltransferase,MFS_1 DYD2_k127_3183473_5 1163617.SCD_n00856 9.642e-187 595.0 COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,2VJ0K@28216|Betaproteobacteria 28216|Betaproteobacteria E Belongs to the peptidase M17 family - - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 DYD2_k127_3183473_16 1380394.JADL01000003_gene5039 5.075e-50 187.0 COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2TUZ6@28211|Alphaproteobacteria,2JU1J@204441|Rhodospirillales 204441|Rhodospirillales S alpha beta - - - - - - - - - - - - - DYD2_k127_3183473_7 1123393.KB891316_gene1344 2.259e-144 461.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,1KRFY@119069|Hydrogenophilales 119069|Hydrogenophilales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt DYD2_k127_3183473_15 215803.DB30_2726 2.051e-52 190.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,42UMS@68525|delta/epsilon subdivisions,2WQA3@28221|Deltaproteobacteria,2YVD7@29|Myxococcales 28221|Deltaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287,ko:K18589 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - - DHFR_1 DYD2_k127_3183473_17 1349767.GJA_2697 3.207e-37 152.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,476MG@75682|Oxalobacteraceae 28216|Betaproteobacteria S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 DYD2_k127_3183473_3 1288494.EBAPG3_13140 4.105e-201 631.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,372I8@32003|Nitrosomonadales 28216|Betaproteobacteria E Belongs to the Orn Lys Arg decarboxylase class-II family - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC DYD2_k127_3183473_11 1163617.SCD_n01869 5.648e-104 342.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria 28216|Betaproteobacteria F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase DYD2_k127_3183473_6 1000565.METUNv1_02967 1.599e-176 559.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,2KV2W@206389|Rhodocyclales 206389|Rhodocyclales D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA DYD2_k127_3183473_0 243233.MCA0016 7.256e-306 950.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1XE7K@135618|Methylococcales 135618|Methylococcales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind DYD2_k127_3183473_13 580332.Slit_1269 6.087e-85 299.0 COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria,44VWF@713636|Nitrosomonadales 28216|Betaproteobacteria T adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - Guanylate_cyc,PEGA DYD2_k127_3183473_18 1163617.SCD_n01783 3.967e-32 129.0 COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria 28216|Betaproteobacteria NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - - DYD2_k127_3183473_9 395494.Galf_1181 1.764e-116 388.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales 28216|Betaproteobacteria KLT PFAM Serine threonine-protein kinase-like domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PEGA,Pkinase DYD2_k127_3183473_8 420324.KI912029_gene269 1.83e-143 467.0 COG4948@1|root,COG4948@2|Bacteria,1R9J6@1224|Proteobacteria,2TVSM@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD2_k127_3183473_14 1231391.AMZF01000022_gene1244 1.398e-58 215.0 COG0412@1|root,COG0412@2|Bacteria,1R5J6@1224|Proteobacteria,2VU7E@28216|Betaproteobacteria 28216|Betaproteobacteria Q dienelactone hydrolase - - - - - - - - - - - - DLH DYD2_k127_3191372_7 485915.Dret_0949 6.631e-53 195.0 2EGX7@1|root,33APC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_3191372_9 485915.Dret_0950 6.389e-38 152.0 2DQBG@1|root,335T7@2|Bacteria,1N795@1224|Proteobacteria,42VWE@68525|delta/epsilon subdivisions,2WRT6@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - - - - - - - - - - GRDB DYD2_k127_3191372_8 1123504.JQKD01000038_gene3016 4.329e-45 175.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria 1224|Proteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - - - - - - - - - - - ECH_1 DYD2_k127_3191372_4 1123368.AUIS01000019_gene1205 5.169e-126 415.0 COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM Succinylglutamate desuccinylase Aspartoacylase - - - - - - - - - - - - AstE_AspA DYD2_k127_3191372_2 1454004.AW11_03159 7.029e-163 529.0 COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,2VNUH@28216|Betaproteobacteria 28216|Betaproteobacteria S glutamate--cysteine ligase - - - - - - - - - - - - GCS2 DYD2_k127_3191372_6 1255043.TVNIR_2084 6.509e-61 224.0 COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,1S3WT@1236|Gammaproteobacteria,1WY7Z@135613|Chromatiales 135613|Chromatiales KT HD domain - - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - HD_4 DYD2_k127_3191372_3 497321.C664_12015 1.762e-137 449.0 COG2223@1|root,COG2223@2|Bacteria,1QVKP@1224|Proteobacteria,2WGTA@28216|Betaproteobacteria,2KZWK@206389|Rhodocyclales 206389|Rhodocyclales P Major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_3191372_0 1207063.P24_03830 0.0 1289.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,2JP8A@204441|Rhodospirillales 204441|Rhodospirillales C FAD linked oxidases, C-terminal domain - - - ko:K18930 - - - - ko00000 - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8 DYD2_k127_3191372_1 1380394.JADL01000014_gene152 1.195e-185 614.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,2JQ78@204441|Rhodospirillales 204441|Rhodospirillales E Aminotransferase class-V - - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD2_k127_3191372_5 1380394.JADL01000001_gene2976 2.329e-125 407.0 COG1082@1|root,COG1082@2|Bacteria,1R8NU@1224|Proteobacteria,2VDZU@28211|Alphaproteobacteria,2JUZV@204441|Rhodospirillales 204441|Rhodospirillales G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 DYD2_k127_3199758_1 1000565.METUNv1_02131 1.713e-245 776.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,2KVA2@206389|Rhodocyclales 206389|Rhodocyclales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD2_k127_3199758_2 1121035.AUCH01000005_gene60 2.717e-185 598.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,2KUN3@206389|Rhodocyclales 206389|Rhodocyclales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 DYD2_k127_3199758_14 580332.Slit_2446 2.666e-46 172.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,44VVR@713636|Nitrosomonadales 28216|Betaproteobacteria S Yqey-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY DYD2_k127_3199758_16 1159870.KB907784_gene2603 9.335e-31 122.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,3T4HS@506|Alcaligenaceae 28216|Betaproteobacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU - - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 DYD2_k127_3199758_4 395494.Galf_0206 2.18e-131 429.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,44VK7@713636|Nitrosomonadales 28216|Betaproteobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 DYD2_k127_3199758_12 883126.HMPREF9710_01556 6.759e-63 221.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,472B0@75682|Oxalobacteraceae 28216|Betaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf DYD2_k127_3199758_15 1163617.SCD_n02454 2.841e-39 149.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB DYD2_k127_3199758_5 1163617.SCD_n02456 9.776e-130 420.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria 28216|Betaproteobacteria D Tyrosine recombinase xerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD2_k127_3199758_13 153948.NAL212_2725 1.769e-52 190.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VU5R@28216|Betaproteobacteria,3731J@32003|Nitrosomonadales 28216|Betaproteobacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 DYD2_k127_3199758_3 1144319.PMI16_01386 1.066e-181 574.0 COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2W9AN@28216|Betaproteobacteria,477ZK@75682|Oxalobacteraceae 28216|Betaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 5.1.2.2 ko:K01781 ko00627,ko01120,map00627,map01120 - R03791,R04161 RC00998 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N DYD2_k127_3199758_0 861299.J421_0317 1.765e-277 870.0 28JZZ@1|root,2Z9PZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_3199758_10 378806.STAUR_6729 3.057e-80 275.0 COG2085@1|root,COG2085@2|Bacteria,1RCXR@1224|Proteobacteria,43070@68525|delta/epsilon subdivisions,2WVFX@28221|Deltaproteobacteria,2Z1E9@29|Myxococcales 28221|Deltaproteobacteria S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD2_k127_3199758_11 404589.Anae109_4238 1.423e-64 224.0 COG2030@1|root,COG2030@2|Bacteria,1RJN8@1224|Proteobacteria 1224|Proteobacteria I dehydratase - - - - - - - - - - - - MaoC_dehydratas DYD2_k127_3199758_8 365044.Pnap_0869 7.417e-87 299.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_3199758_9 1211115.ALIQ01000007_gene1069 1.301e-84 291.0 COG0656@1|root,COG0656@2|Bacteria,1PENK@1224|Proteobacteria,2V8CZ@28211|Alphaproteobacteria,3NCS5@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD2_k127_3199758_7 1469245.JFBG01000062_gene2270 1.504e-119 392.0 COG2358@1|root,COG2358@2|Bacteria 2|Bacteria G TRAP transporter, solute receptor (TAXI family MA20_27285 - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD2_k127_3199758_6 1469245.JFBG01000062_gene2271 2.086e-128 419.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM DYD2_k127_3202801_18 1288494.EBAPG3_9380 1.192e-36 141.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,372ZZ@32003|Nitrosomonadales 28216|Betaproteobacteria Q MlaD protein mlaD - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD2_k127_3202801_4 1288494.EBAPG3_9390 5.751e-131 424.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,3728G@32003|Nitrosomonadales 28216|Betaproteobacteria Q Permease MlaE ttg2B - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD2_k127_3202801_7 1485544.JQKP01000001_gene1099 6.765e-128 413.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,44VBC@713636|Nitrosomonadales 28216|Betaproteobacteria Q ABC transporter ttg2A - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD2_k127_3202801_6 713586.KB900536_gene1410 4.458e-128 420.0 COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,1SCEP@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Luciferase-like monooxygenase luxA - 1.14.14.3 ko:K00494 ko02020,ko02024,map02020,map02024 - R10551 RC00080 ko00000,ko00001,ko01000 - - - Bac_luciferase DYD2_k127_3202801_13 1123368.AUIS01000001_gene1922 5.633e-61 221.0 COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,2NC2R@225057|Acidithiobacillales 225057|Acidithiobacillales GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - - - - - - - - - - - Epimerase DYD2_k127_3202801_12 545276.KB898726_gene954 8.419e-64 228.0 COG3396@1|root,COG3396@2|Bacteria,1NJ4Y@1224|Proteobacteria,1SGSK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S P-aminobenzoate N-oxygenase AurF - - - - - - - - - - - - AurF DYD2_k127_3202801_9 3988.XP_002536083.1 1.038e-88 298.0 COG1131@1|root,KOG0059@2759|Eukaryota 2759|Eukaryota V ATPase activity, coupled to transmembrane movement of substances - - - - - - - - - - - - ABC_tran DYD2_k127_3202801_1 1123393.KB891328_gene592 2.561e-205 649.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria,1KS6P@119069|Hydrogenophilales 119069|Hydrogenophilales T Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD2_k127_3202801_5 1165096.ARWF01000001_gene1422 6.39e-130 434.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VMD2@28216|Betaproteobacteria,2KKBN@206350|Nitrosomonadales 206350|Nitrosomonadales U PFAM Sporulation domain protein - - - - - - - - - - - - AAA_22,SPOR DYD2_k127_3202801_8 1123392.AQWL01000004_gene2750 7.767e-128 432.0 COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,1KSY9@119069|Hydrogenophilales 119069|Hydrogenophilales NU Secretin and TonB N terminus short domain - - - - - - - - - - - - Secretin DYD2_k127_3202801_16 582744.Msip34_0080 3.063e-42 171.0 COG3118@1|root,COG3118@2|Bacteria 2|Bacteria O belongs to the thioredoxin family trxA - - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - iIT341.HP0824 TPR_16,TPR_19,Thioredoxin DYD2_k127_3202801_0 557598.LHK_01055 5.444e-211 670.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KPJS@206351|Neisseriales 206351|Neisseriales NU type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N DYD2_k127_3202801_3 582744.Msip34_0082 4.231e-145 471.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,2KKSQ@206350|Nitrosomonadales 206350|Nitrosomonadales NU PFAM type II secretion system - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF DYD2_k127_3202801_10 1101195.Meth11DRAFT_0144 6.611e-80 286.0 2CG4C@1|root,2Z8MQ@2|Bacteria,1R6PQ@1224|Proteobacteria,2VHKG@28216|Betaproteobacteria,2KKMA@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - DYD2_k127_3202801_19 583345.Mmol_0247 1.452e-26 120.0 2E6RE@1|root,331BH@2|Bacteria,1N8K0@1224|Proteobacteria,2VWUF@28216|Betaproteobacteria,2KMZY@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - DYD2_k127_3202801_14 1163617.SCD_n00566 7.236e-48 187.0 2DNAT@1|root,32WH7@2|Bacteria,1N2AT@1224|Proteobacteria,2VV51@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3202801_17 1304883.KI912532_gene1638 1.436e-41 164.0 COG2165@1|root,COG2165@2|Bacteria,1RHE1@1224|Proteobacteria,2VSJ6@28216|Betaproteobacteria,2KWRU@206389|Rhodocyclales 206389|Rhodocyclales NU general secretion pathway protein - - - - - - - - - - - - N_methyl DYD2_k127_3202801_2 1236959.BAMT01000006_gene424 5.143e-149 490.0 COG0642@1|root,COG0642@2|Bacteria,1R49A@1224|Proteobacteria,2VKU5@28216|Betaproteobacteria,2KMC6@206350|Nitrosomonadales 206350|Nitrosomonadales T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c DYD2_k127_3202801_15 1349767.GJA_2100 2.137e-47 183.0 2DNTZ@1|root,32Z4F@2|Bacteria,1NA30@1224|Proteobacteria 1224|Proteobacteria - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - DYD2_k127_3202801_11 1198452.Jab_2c02510 2.499e-64 228.0 2EMEM@1|root,33F3F@2|Bacteria,1NK08@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_3202801_20 1469245.JFBG01000027_gene1443 9.72e-17 81.0 COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,1SF74@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl DYD2_k127_3242693_2 519989.ECTPHS_08261 2.68e-107 353.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase DYD2_k127_3242693_3 1348657.M622_08695 3.556e-91 311.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,2KU90@206389|Rhodocyclales 206389|Rhodocyclales E Prephenate dehydrogenase tyrA - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH DYD2_k127_3242693_0 580332.Slit_2064 4.761e-151 486.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,44V48@713636|Nitrosomonadales 28216|Betaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC2 - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_3242693_1 1266925.JHVX01000006_gene2215 8.434e-134 436.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,371MR@32003|Nitrosomonadales 28216|Betaproteobacteria E Prephenate dehydratase pheA - 4.2.1.51,4.2.1.91,5.4.99.5 ko:K01713,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT DYD2_k127_327010_2 1095769.CAHF01000013_gene3343 1.398e-50 182.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,473B3@75682|Oxalobacteraceae 28216|Betaproteobacteria F Deoxynucleoside kinase dgk - - - - - - - - - - - dNK DYD2_k127_327010_0 1095769.CAHF01000022_gene41 1.709e-103 346.0 COG1024@1|root,COG1024@2|Bacteria,1MUD7@1224|Proteobacteria,2VQ37@28216|Betaproteobacteria 28216|Betaproteobacteria I Pfam Enoyl-CoA hydratase isomerase - - - ko:K13816 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - ECH_1 DYD2_k127_327010_4 1173263.Syn7502_03606 9.115e-31 130.0 COG5031@1|root,COG5031@2|Bacteria,1G5JB@1117|Cyanobacteria,1GZN7@1129|Synechococcus 1117|Cyanobacteria H Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - - - - - - - - - - Coq4 DYD2_k127_327010_1 1109445.AGSX01000108_gene1215 1.713e-58 214.0 COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,1RT3H@1236|Gammaproteobacteria,1YZZD@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 DYD2_k127_327010_3 580332.Slit_1289 1.461e-43 169.0 COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - 2.7.13.3 ko:K10715 ko02020,ko02024,map02020,map02024 M00517 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE2,HATPase_c,HisKA,Hpt,Response_reg DYD2_k127_3281735_14 1163617.SCD_n02749 2.6e-82 309.0 COG2982@1|root,COG2982@2|Bacteria,1QZY2@1224|Proteobacteria,2VTEI@28216|Betaproteobacteria 28216|Betaproteobacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - - DYD2_k127_3281735_6 1131553.JIBI01000027_gene2401 6.017e-136 438.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,372AH@32003|Nitrosomonadales 28216|Betaproteobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 DYD2_k127_3281735_20 765912.Thimo_1845 7.365e-58 204.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1WYB4@135613|Chromatiales 135613|Chromatiales J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase DYD2_k127_3281735_24 748247.AZKH_0279 7.793e-24 105.0 COG2159@1|root,COG2159@2|Bacteria,1R7E1@1224|Proteobacteria,2VPY4@28216|Betaproteobacteria,2KVED@206389|Rhodocyclales 206389|Rhodocyclales S Amidohydrolase uxuA - 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD2_k127_3281735_10 56780.SYN_02005 1.651e-105 353.0 COG2199@1|root,COG3706@2|Bacteria,1RCC4@1224|Proteobacteria,43AED@68525|delta/epsilon subdivisions,2WQS7@28221|Deltaproteobacteria 1224|Proteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF DYD2_k127_3281735_18 1485544.JQKP01000017_gene605 4.507e-62 224.0 28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,44UZS@713636|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF3025) - - - - - - - - - - - - DUF3025 DYD2_k127_3281735_5 795666.MW7_1742 7.276e-139 450.0 COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2VIKG@28216|Betaproteobacteria,1K411@119060|Burkholderiaceae 28216|Betaproteobacteria S Fad dependent oxidoreductase lhgO - 1.4.3.3 ko:K00273 ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146 - R00366,R02457,R02894,R02923,R04221,R07400 RC00006,RC00018,RC00135 ko00000,ko00001,ko01000 - - - DAO DYD2_k127_3281735_26 748247.AZKH_p0309 6.073e-15 84.0 COG0642@1|root,COG0784@1|root,COG4192@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG4192@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg DYD2_k127_3281735_23 172088.AUGA01000041_gene4866 2.623e-34 145.0 COG0251@1|root,COG0251@2|Bacteria,1RAKQ@1224|Proteobacteria,2U5F4@28211|Alphaproteobacteria,3JYCE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Endoribonuclease L-PSP MA20_36215 - - - - - - - - - - - Ribonuc_L-PSP DYD2_k127_3281735_9 1288494.EBAPG3_23550 4.267e-108 357.0 COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VU4X@28216|Betaproteobacteria,372W6@32003|Nitrosomonadales 28216|Betaproteobacteria S Prolyl oligopeptidase family - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 DYD2_k127_3281735_1 1380394.JADL01000004_gene5920 6.57e-231 728.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TSME@28211|Alphaproteobacteria,2JQW6@204441|Rhodospirillales 204441|Rhodospirillales E Gamma-glutamyltranspeptidase - - - - - - - - - - - - G_glu_transpept DYD2_k127_3281735_16 1121861.KB899936_gene400 9.497e-74 280.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JSUV@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_3281735_2 710686.Mycsm_00611 2.209e-210 666.0 COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,2354G@1762|Mycobacteriaceae 201174|Actinobacteria E gamma-glutamyltransferase ggtA - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD2_k127_3281735_17 395964.KE386496_gene2447 1.1e-70 241.0 COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2U99X@28211|Alphaproteobacteria 28211|Alphaproteobacteria O redox protein regulator of disulfide bond formation - - - - - - - - - - - - OsmC DYD2_k127_3281735_3 1002672.SAR11G3_00190 8.354e-190 602.0 COG1840@1|root,COG1840@2|Bacteria,1MWWI@1224|Proteobacteria,2VF0S@28211|Alphaproteobacteria,4BTD5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_6 DYD2_k127_3281735_0 1211115.ALIQ01000189_gene864 2.196e-255 798.0 COG1178@1|root,COG1178@2|Bacteria,1R0MN@1224|Proteobacteria,2VFDY@28211|Alphaproteobacteria 28211|Alphaproteobacteria P binding-protein-dependent transport systems inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 DYD2_k127_3281735_7 1123060.JONP01000006_gene4826 2.912e-131 428.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 DYD2_k127_3281735_19 292415.Tbd_0861 4.072e-58 208.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2VSHT@28216|Betaproteobacteria 28216|Betaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF924 DYD2_k127_3281735_21 285535.JOEY01000073_gene9814 1.242e-57 213.0 COG0329@1|root,COG0329@2|Bacteria,2I92Q@201174|Actinobacteria 201174|Actinobacteria EM Belongs to the DapA family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD2_k127_3281735_15 1356854.N007_12890 1.209e-77 272.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HD58@91061|Bacilli 91061|Bacilli E Ornithine cyclodeaminase - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD2_k127_3281735_12 1125973.JNLC01000010_gene1773 4.809e-100 336.0 COG1809@1|root,COG1809@2|Bacteria,1MUQY@1224|Proteobacteria,2U1YM@28211|Alphaproteobacteria,3JXWR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S (2R)-phospho-3-sulfolactate synthase (ComA) - - - - - - - - - - - - ComA DYD2_k127_3281735_4 1123368.AUIS01000009_gene2449 2.351e-140 456.0 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria,2NCP1@225057|Acidithiobacillales 225057|Acidithiobacillales S FIST N domain - - - - - - - - - - - - FIST,FIST_C DYD2_k127_3281735_13 1454004.AW11_00293 1.272e-93 314.0 COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,1KQB6@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria I Enoyl-CoA hydratase/isomerase fadB3 - - - - - - - - - - - ECH_1 DYD2_k127_3281735_8 1095769.CAHF01000005_gene1585 3.316e-122 400.0 COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2VX5D@28216|Betaproteobacteria 28216|Betaproteobacteria V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid vgb - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - - DYD2_k127_3281735_22 504832.OCAR_6189 1.428e-40 157.0 COG0664@1|root,COG0664@2|Bacteria,1Q93V@1224|Proteobacteria,2TTEY@28211|Alphaproteobacteria,3JS14@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T cyclic nucleotide-binding - - - - - - - - - - - - Imp-YgjV,cNMP_binding DYD2_k127_3281735_11 395495.Lcho_0045 2.887e-105 347.0 COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria 28216|Betaproteobacteria T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg DYD2_k127_3380087_19 1288494.EBAPG3_4420 2.499e-19 91.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,372QW@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind DYD2_k127_3380087_3 580332.Slit_1063 6.49e-189 600.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,44VBG@713636|Nitrosomonadales 28216|Betaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD2_k127_3380087_6 243231.GSU1099 1.417e-148 477.0 COG0226@1|root,COG0226@2|Bacteria,1PVGI@1224|Proteobacteria,43A46@68525|delta/epsilon subdivisions,2X1XS@28221|Deltaproteobacteria,43VRM@69541|Desulfuromonadales 28221|Deltaproteobacteria P PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - - DYD2_k127_3380087_4 640081.Dsui_3055 1.01e-154 493.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,2KU94@206389|Rhodocyclales 206389|Rhodocyclales P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 DYD2_k127_3380087_7 228410.NE1000 4.31e-145 466.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,372RN@32003|Nitrosomonadales 28216|Betaproteobacteria P Phosphate transport system permease protein pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 DYD2_k127_3380087_8 1288494.EBAPG3_21370 1.37e-142 457.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,372RB@32003|Nitrosomonadales 28216|Betaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran DYD2_k127_3380087_10 1123393.KB891327_gene374 4.871e-94 315.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,1KRM4@119069|Hydrogenophilales 119069|Hydrogenophilales F Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) - - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM DYD2_k127_3380087_17 1288494.EBAPG3_21390 2.02e-30 124.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,373HX@32003|Nitrosomonadales 28216|Betaproteobacteria U Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG DYD2_k127_3380087_15 265072.Mfla_2061 1.083e-54 194.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,2KMRP@206350|Nitrosomonadales 206350|Nitrosomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 DYD2_k127_3380087_9 264198.Reut_A0962 3.135e-97 318.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,1K10B@119060|Burkholderiaceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 DYD2_k127_3380087_12 1031711.RSPO_c01374 1.193e-87 297.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1K15D@119060|Burkholderiaceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa DYD2_k127_3380087_1 261292.Nit79A3_2930 3.976e-248 769.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,371Z7@32003|Nitrosomonadales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa DYD2_k127_3380087_14 323848.Nmul_A1095 8.789e-69 247.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,371SU@32003|Nitrosomonadales 28216|Betaproteobacteria C Thioredoxin-like [2Fe-2S] ferredoxin nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx DYD2_k127_3380087_2 1392838.AWNM01000028_gene4256 5.523e-229 717.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,3T384@506|Alcaligenaceae 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB DYD2_k127_3380087_0 1288494.EBAPG3_21460 4.4e-318 992.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,372H6@32003|Nitrosomonadales 28216|Betaproteobacteria C Molybdopterin oxidoreductase Fe4S4 domain nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD2_k127_3380087_5 323848.Nmul_A1098 1.972e-151 489.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,371TY@32003|Nitrosomonadales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD2_k127_3380087_11 1288494.EBAPG3_21480 1.665e-88 300.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,371MN@32003|Nitrosomonadales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 DYD2_k127_3380087_13 292415.Tbd_1151 2.02e-78 267.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,1KS7Z@119069|Hydrogenophilales 119069|Hydrogenophilales C NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD2_k127_3380087_16 426114.THI_2629 5.54e-42 163.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,1KM2T@119065|unclassified Burkholderiales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD2_k127_3380087_18 497321.C664_02840 3.479e-26 109.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,2KUJW@206389|Rhodocyclales 206389|Rhodocyclales CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N DYD2_k127_339007_22 261292.Nit79A3_1044 4.883e-19 86.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,3724H@32003|Nitrosomonadales 28216|Betaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD2_k127_339007_13 1415778.JQMM01000001_gene1401 2.347e-60 210.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1J69H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_5014 PRA-CH,PRA-PH DYD2_k127_339007_17 557598.LHK_00192 3.763e-36 141.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,2KRIM@206351|Neisseriales 206351|Neisseriales E Psort location Cytoplasmic, score hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH DYD2_k127_339007_21 497321.C664_04752 1.032e-21 96.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,2KX8N@206389|Rhodocyclales 206389|Rhodocyclales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD2_k127_339007_19 640081.Dsui_1423 1.095e-30 126.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KWT9@206389|Rhodocyclales 206389|Rhodocyclales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD2_k127_339007_7 1000565.METUNv1_02442 7.177e-98 326.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,2KUWA@206389|Rhodocyclales 206389|Rhodocyclales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC DYD2_k127_339007_2 1266925.JHVX01000004_gene1313 2.927e-148 479.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,37267@32003|Nitrosomonadales 28216|Betaproteobacteria O Belongs to the peptidase S1C family degQ - - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 DYD2_k127_339007_12 1286631.X805_08750 9.284e-77 263.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,1KJ5I@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N DYD2_k127_339007_0 1095769.CAHF01000003_gene986 9.152e-208 655.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,4727H@75682|Oxalobacteraceae 28216|Betaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B DYD2_k127_339007_9 1123367.C666_01585 6.123e-89 300.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,2KUIS@206389|Rhodocyclales 206389|Rhodocyclales P Cytochrome C1 petC - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 DYD2_k127_339007_6 323848.Nmul_A1002 9.542e-108 353.0 COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,372NI@32003|Nitrosomonadales 28216|Betaproteobacteria O Glutathione S-transferase, N-terminal domain sspA - - ko:K03599 - - - - ko00000,ko02000,ko03021 1.A.12.3.1 - - GST_C,GST_C_2,GST_N,GST_N_3 DYD2_k127_339007_16 1120999.JONM01000010_gene4074 9.615e-40 153.0 COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,2KRB7@206351|Neisseriales 206351|Neisseriales S Stringent starvation protein B sspB - - ko:K03600 - - - - ko00000,ko03021 - - - SspB DYD2_k127_339007_3 240016.ABIZ01000001_gene3117 3.371e-123 403.0 COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran DYD2_k127_339007_10 1123073.KB899242_gene1477 1.403e-86 293.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales 135614|Xanthomonadales S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 DYD2_k127_339007_5 1121405.dsmv_1085 1.444e-112 387.0 COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales 28221|Deltaproteobacteria N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux DYD2_k127_339007_23 1121405.dsmv_1086 5.116e-18 98.0 2AF4E@1|root,31534@2|Bacteria,1NEPN@1224|Proteobacteria,42WGJ@68525|delta/epsilon subdivisions,2WRTJ@28221|Deltaproteobacteria,2MM2R@213118|Desulfobacterales 28221|Deltaproteobacteria S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 DYD2_k127_339007_11 1231391.AMZF01000094_gene118 1.445e-77 275.0 COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria 28216|Betaproteobacteria EGP major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_339007_8 1231391.AMZF01000094_gene118 6.76e-97 331.0 COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria 28216|Betaproteobacteria EGP major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_339007_4 1144312.PMI09_04994 2.499e-114 380.0 COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2TWC9@28211|Alphaproteobacteria,4BDHI@82115|Rhizobiaceae 28211|Alphaproteobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_339007_1 1532557.JL37_19035 6.755e-168 544.0 COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria 28216|Betaproteobacteria EH Belongs to the TPP enzyme family - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_339007_18 391735.Veis_2974 2.36e-35 138.0 COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,2VSYU@28216|Betaproteobacteria,4AEKB@80864|Comamonadaceae 28216|Betaproteobacteria S Carboxymuconolactone decarboxylase family pcaC - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - Abhydrolase_1,CMD DYD2_k127_339007_14 1163617.SCD_n02073 5.613e-56 201.0 2CCFR@1|root,2Z7VF@2|Bacteria,1MXHU@1224|Proteobacteria,2VHMR@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_339007_20 93220.LV28_21370 2.52e-30 121.0 COG1011@1|root,COG1011@2|Bacteria,1MU1H@1224|Proteobacteria,2VN8N@28216|Betaproteobacteria,1K3YZ@119060|Burkholderiaceae 28216|Betaproteobacteria S Haloacid dehalogenase, type II - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 DYD2_k127_3399664_5 153948.NAL212_0503 4.25e-102 337.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,372WT@32003|Nitrosomonadales 28216|Betaproteobacteria I Belongs to the thiolase family bktB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD2_k127_3399664_6 1163617.SCD_n02317 2.397e-94 317.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria 28216|Betaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 DYD2_k127_3399664_2 1163617.SCD_n00732 3.414e-170 551.0 COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria 28216|Betaproteobacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 DYD2_k127_3399664_3 1163617.SCD_n00733 2.27e-168 543.0 COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria 28216|Betaproteobacteria S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD2_k127_3399664_1 543913.D521_1841 2.271e-192 610.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,1KQD9@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP DYD2_k127_3399664_8 709797.CSIRO_0460 1.843e-47 177.0 COG4665@1|root,COG4665@2|Bacteria,1RHEX@1224|Proteobacteria,2UAEX@28211|Alphaproteobacteria,3K4HR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD2_k127_3399664_0 887062.HGR_08324 1.862e-192 609.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,4ABNC@80864|Comamonadaceae 28216|Betaproteobacteria Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM DYD2_k127_3399664_4 290397.Adeh_3929 2.17e-111 376.0 COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales 28221|Deltaproteobacteria L Belongs to the FPG family - - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD2_k127_3399664_7 1380394.JADL01000020_gene1825 4.29e-56 211.0 COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,2TWKE@28211|Alphaproteobacteria,2JRIW@204441|Rhodospirillales 28211|Alphaproteobacteria E Methylenetetrahydrofolate reductase - - - - - - - - - - - - MTHFR DYD2_k127_3416072_26 349521.HCH_07075 3.105e-15 81.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1XK2G@135619|Oceanospirillales 135619|Oceanospirillales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP DYD2_k127_3416072_27 69014.TK0815 1.036e-14 75.0 COG1225@1|root,arCOG00310@2157|Archaea,2XY0E@28890|Euryarchaeota,2440M@183968|Thermococci 183968|Thermococci O SCO1/SenC - - - - - - - - - - - - AhpC-TSA DYD2_k127_3416072_30 1050202.KB913024_gene2297 2.321e-06 50.0 COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,407P7@622450|Actinopolysporales 201174|Actinobacteria O Redoxin ahpE GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - AhpC-TSA DYD2_k127_3416072_7 420662.Mpe_A1234 5.313e-156 499.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VJNS@28216|Betaproteobacteria,1KJXY@119065|unclassified Burkholderiales 28216|Betaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH DYD2_k127_3416072_9 402626.Rpic_4541 3.845e-132 428.0 COG0583@1|root,COG0583@2|Bacteria,1MUIX@1224|Proteobacteria,2VI6K@28216|Betaproteobacteria,1K274@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator metR - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD2_k127_3416072_2 267608.RSp0676 5.459e-317 987.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2VI04@28216|Betaproteobacteria,1K121@119060|Burkholderiaceae 28216|Betaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 DYD2_k127_3416072_13 472759.Nhal_3413 1.425e-119 389.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1X250@135613|Chromatiales 135613|Chromatiales S Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD2_k127_3416072_25 1173264.KI913949_gene4298 2.178e-16 87.0 COG2059@1|root,COG2059@2|Bacteria,1G37Z@1117|Cyanobacteria,1HA7A@1150|Oscillatoriales 1117|Cyanobacteria P TIGRFAM chromate transporter, chromate ion transporter (CHR) family chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD2_k127_3416072_28 1382304.JNIL01000001_gene1101 9.692e-09 64.0 COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,4IQZC@91061|Bacilli 91061|Bacilli P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD2_k127_3416072_12 1298867.AUES01000029_gene2373 3.142e-123 408.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3JWBY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_3416072_17 1121396.KB893058_gene2565 1.52e-64 235.0 COG0657@1|root,COG0657@2|Bacteria 2|Bacteria I acetylesterase activity - - 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3,Peptidase_S9 DYD2_k127_3416072_14 1380394.JADL01000013_gene705 8.228e-119 391.0 COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,2TRM8@28211|Alphaproteobacteria,2JW3Y@204441|Rhodospirillales 204441|Rhodospirillales EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_3416072_6 472759.Nhal_1348 7.112e-162 528.0 COG1858@1|root,COG1858@2|Bacteria,1RC4D@1224|Proteobacteria,1SJKT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome C peroxidase - - - - - - - - - - - - - DYD2_k127_3416072_19 580332.Slit_1269 5.56e-57 212.0 COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria,44VWF@713636|Nitrosomonadales 28216|Betaproteobacteria T adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - Guanylate_cyc,PEGA DYD2_k127_3416072_11 614083.AWQR01000055_gene1979 1.234e-124 405.0 COG2972@1|root,COG2972@2|Bacteria,1QYRK@1224|Proteobacteria,2WHJ2@28216|Betaproteobacteria,4AGMA@80864|Comamonadaceae 28216|Betaproteobacteria T Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365,HAMP DYD2_k127_3416072_23 870187.Thini_2693 3e-22 102.0 2ES2F@1|root,33JMD@2|Bacteria,1NQFF@1224|Proteobacteria,1SJHV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3416072_31 596154.Alide2_2863 3.667e-05 52.0 COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2VX5E@28216|Betaproteobacteria,4AJJ9@80864|Comamonadaceae 28216|Betaproteobacteria S SMART Transport-associated and nodulation - - - - - - - - - - - - BON DYD2_k127_3416072_18 358396.C445_06820 2.22e-61 226.0 COG0604@1|root,arCOG01458@2157|Archaea,2XV8Q@28890|Euryarchaeota,23TWD@183963|Halobacteria 183963|Halobacteria C NADPH quinone - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD2_k127_3416072_3 517417.Cpar_0798 1.014e-206 672.0 COG3387@1|root,COG3387@2|Bacteria,1FE8X@1090|Chlorobi 1090|Chlorobi G Glycoside hydrolase 15-related - - - - - - - - - - - - DUF547,Glyco_hydro_15 DYD2_k127_3416072_10 84531.JMTZ01000030_gene152 5.909e-125 407.0 COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales 135614|Xanthomonadales G 6-phosphogluconate dehydrogenase gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 DYD2_k127_3416072_4 1499967.BAYZ01000095_gene4213 9.817e-172 553.0 COG0364@1|root,COG0364@2|Bacteria,2NNUR@2323|unclassified Bacteria 2|Bacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - iIT341.HP1101 G6PD_C,G6PD_N DYD2_k127_3416072_20 1499967.BAYZ01000095_gene4212 3.078e-50 190.0 COG0363@1|root,COG0363@2|Bacteria,2NPBM@2323|unclassified Bacteria 2|Bacteria G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,3.1.1.31 ko:K00851,ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R01737,R02035 RC00002,RC00017,RC00537 ko00000,ko00001,ko00002,ko01000 - - iLJ478.TM1154 Glucosamine_iso DYD2_k127_3416072_0 243231.GSU2758 0.0 2522.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42P3V@68525|delta/epsilon subdivisions,2WKWV@28221|Deltaproteobacteria,43TF0@69541|Desulfuromonadales 28221|Deltaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA1 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD2_k127_3416072_15 859657.RPSI07_3031 6.837e-110 362.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHUJ@28216|Betaproteobacteria,1K1GV@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C DYD2_k127_3416072_5 522306.CAP2UW1_1014 1.889e-165 537.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KQIU@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria F DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C DYD2_k127_3416072_8 76114.ebA6730 3.595e-138 450.0 2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2W0ZB@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3416072_16 948106.AWZT01000001_gene5340 7.85e-105 353.0 COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2VKR0@28216|Betaproteobacteria,1K2I8@119060|Burkholderiaceae 28216|Betaproteobacteria K Cupin - - - - - - - - - - - - Cupin_6,HTH_18 DYD2_k127_3416072_1 85643.Tmz1t_1360 0.0 1341.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,2KUCG@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC DYD2_k127_3416072_22 316058.RPB_1947 1.813e-24 111.0 COG3779@1|root,COG3779@2|Bacteria,1R3Q7@1224|Proteobacteria,2UFEG@28211|Alphaproteobacteria,3JV72@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2314) - - - - - - - - - - - - DUF2314 DYD2_k127_3416072_21 1101195.Meth11DRAFT_1787 2.363e-36 150.0 COG4520@1|root,COG4520@2|Bacteria,1RIHU@1224|Proteobacteria,2VTAT@28216|Betaproteobacteria,2KNS8@206350|Nitrosomonadales 206350|Nitrosomonadales M Glycine zipper - - - - - - - - - - - - Rick_17kDa_Anti DYD2_k127_3454547_0 948106.AWZT01000001_gene5084 1.541e-317 985.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,1K1D1@119060|Burkholderiaceae 28216|Betaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_3454547_9 1218084.BBJK01000007_gene913 2.355e-69 244.0 COG2080@1|root,COG2080@2|Bacteria,1PI3V@1224|Proteobacteria,2W6PI@28216|Betaproteobacteria,1KC83@119060|Burkholderiaceae 28216|Betaproteobacteria C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 DYD2_k127_3454547_2 1218084.BBJK01000007_gene906 6.282e-257 800.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2W1P1@28216|Betaproteobacteria,1K0XN@119060|Burkholderiaceae 28216|Betaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - - - - - - - - - - UbiD DYD2_k127_3454547_10 1095769.CAHF01000022_gene126 2.87e-69 247.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4731A@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_3454547_6 452637.Oter_3727 2.043e-110 367.0 COG1475@1|root,COG1475@2|Bacteria 2|Bacteria K chromosome segregation - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc DYD2_k127_3454547_11 388413.ALPR1_19863 2.878e-37 149.0 2BD06@1|root,326MC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_3454547_1 795666.MW7_3261 4.164e-301 934.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,1JZU5@119060|Burkholderiaceae 28216|Betaproteobacteria T GTP-binding protein typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 DYD2_k127_3454547_3 1207063.P24_11802 5.325e-145 470.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,2JPUE@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the peptidase M20A family. ArgE subfamily argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 DYD2_k127_3454547_4 640081.Dsui_0638 4.966e-123 399.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,2KUY5@206389|Rhodocyclales 206389|Rhodocyclales E ABC-type polar amino acid transport system, ATPase component - - - ko:K10004 ko02010,ko02020,map02010,map02020 M00230 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.19,3.A.1.3.4 - - ABC_tran DYD2_k127_3454547_7 1007105.PT7_2780 2.756e-102 339.0 COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2VIQB@28216|Betaproteobacteria,3T1W5@506|Alcaligenaceae 28216|Betaproteobacteria P With GltJLPS and GadC for glutamate and GltJLP, DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate gltK - - ko:K10002 ko02010,ko02020,map02010,map02020 M00230 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.19,3.A.1.3.4 - - BPD_transp_1 DYD2_k127_3454547_8 1231391.AMZF01000022_gene1247 4.017e-101 334.0 COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,2VJ8A@28216|Betaproteobacteria,3T30B@506|Alcaligenaceae 28216|Betaproteobacteria P ABC transporter permease gltJ - - ko:K02029,ko:K10003 ko02010,ko02020,map02010,map02020 M00230,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 - - BPD_transp_1 DYD2_k127_3454547_5 1535287.JP74_00010 1.129e-122 400.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TTXX@28211|Alphaproteobacteria,3N7YJ@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria ET Bacterial extracellular solute-binding proteins, family 3 gltI - - ko:K02030,ko:K10001 ko02010,ko02020,map02010,map02020 M00230,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 - - SBP_bac_3 DYD2_k127_3476978_6 331869.BAL199_06614 4.18e-31 123.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD2_k127_3476978_1 1038859.AXAU01000026_gene2331 4.69e-155 495.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRS8@28211|Alphaproteobacteria,3JS1M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component nikB - - ko:K02033,ko:K15585 ko02010,ko02024,map02010,map02024 M00239,M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD2_k127_3476978_2 1038859.AXAU01000026_gene2332 1.005e-127 414.0 COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2TRX5@28211|Alphaproteobacteria,3JRYA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N DYD2_k127_3476978_5 883080.HMPREF9697_01896 1.521e-71 256.0 COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2TSS4@28211|Alphaproteobacteria,3JRRK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain catB - 5.1.1.20,5.5.1.1,5.5.1.7 ko:K01856,ko:K01860,ko:K19802 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R04259,R05300,R05390,R05392,R06834,R06840,R06989,R08116,R08119,R09135,R09215,R09217,R09221,R09229,R10938 RC00903,RC01038,RC01108,RC01321,RC01356,RC01358,RC01687,RC02117,RC02448,RC02464,RC02465,RC03309 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N DYD2_k127_3476978_3 1097668.BYI23_C013480 1.893e-85 290.0 COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,1K3K2@119060|Burkholderiaceae 28216|Betaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD2_k127_3476978_0 1095769.CAHF01000023_gene479 3.528e-175 558.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,475Y7@75682|Oxalobacteraceae 28216|Betaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD2_k127_3476978_4 1131553.JIBI01000001_gene1442 9.518e-85 288.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,372PK@32003|Nitrosomonadales 28216|Betaproteobacteria S membrane transporter protein - - - - - - - - - - - - TauE DYD2_k127_3476978_7 765177.Desmu_0942 0.0002762 46.0 COG0402@1|root,arCOG00695@2157|Archaea,2XQ6N@28889|Crenarchaeota 28889|Crenarchaeota F COG0402 Cytosine deaminase and related metal-dependent - - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 DYD2_k127_3508381_0 426355.Mrad2831_5856 0.0 1060.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,1JTKB@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_3508381_2 1380394.JADL01000004_gene5935 7.435e-162 520.0 COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria,2JR5U@204441|Rhodospirillales 204441|Rhodospirillales E Periplasmic binding protein domain - - - - - - - - - - - - Peripla_BP_6 DYD2_k127_3508381_5 1205680.CAKO01000010_gene3902 4.588e-111 366.0 COG0559@1|root,COG0559@2|Bacteria,1R5JM@1224|Proteobacteria,2TUSY@28211|Alphaproteobacteria,2JVGR@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 DYD2_k127_3508381_7 1380394.JADL01000004_gene5933 1.085e-109 362.0 COG4177@1|root,COG4177@2|Bacteria,1PSHZ@1224|Proteobacteria,2TVQQ@28211|Alphaproteobacteria,2JVEV@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 DYD2_k127_3508381_14 1380394.JADL01000004_gene5932 1.288e-77 272.0 COG0411@1|root,COG0411@2|Bacteria,1R3YN@1224|Proteobacteria,2U2IG@28211|Alphaproteobacteria,2JWDY@204441|Rhodospirillales 204441|Rhodospirillales E ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran,BCA_ABC_TP_C DYD2_k127_3508381_8 1187851.A33M_2603 5.774e-107 351.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3FD1Y@34008|Rhodovulum 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD2_k127_3508381_1 1396858.Q666_03635 2.409e-208 655.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,464Z4@72275|Alteromonadaceae 1236|Gammaproteobacteria E alanine symporter dagA - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp DYD2_k127_3508381_12 1205680.CAKO01000040_gene693 5.441e-80 279.0 COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,2TRGF@28211|Alphaproteobacteria,2JV63@204441|Rhodospirillales 204441|Rhodospirillales Q Taurine catabolism dioxygenase TauD, TfdA family - - - - - - - - - - - - TauD DYD2_k127_3508381_17 644801.Psest_1569 1.599e-20 100.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,1S04N@1236|Gammaproteobacteria,1Z1VR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GAF_2,GGDEF,PAS,PAS_3,PAS_4 DYD2_k127_3508381_19 331869.BAL199_06946 3.308e-15 80.0 COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2UF4X@28211|Alphaproteobacteria,4BR0T@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S YCII-related domain yciI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09780 - - - - ko00000 - - - YCII DYD2_k127_3508381_15 296591.Bpro_0351 8.868e-34 134.0 COG0251@1|root,COG0251@2|Bacteria,1REJQ@1224|Proteobacteria,2VYGJ@28216|Betaproteobacteria 28216|Betaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD2_k127_3508381_18 887062.HGR_03457 3.628e-16 83.0 COG2259@1|root,COG2259@2|Bacteria,1RCKY@1224|Proteobacteria,2VYM6@28216|Betaproteobacteria,4AHPQ@80864|Comamonadaceae 28216|Betaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX DYD2_k127_3508381_11 1288494.EBAPG3_1240 6.06e-95 314.0 COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,2VNXE@28216|Betaproteobacteria 28216|Betaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD2_k127_3508381_10 1232410.KI421427_gene1264 5.069e-100 340.0 COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,42R72@68525|delta/epsilon subdivisions,2WMSM@28221|Deltaproteobacteria 28221|Deltaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_3508381_6 1144310.PMI07_001945 7.078e-110 364.0 COG3836@1|root,COG3836@2|Bacteria,1R9U6@1224|Proteobacteria,2TSTY@28211|Alphaproteobacteria,4B7QE@82115|Rhizobiaceae 28211|Alphaproteobacteria G Belongs to the HpcH HpaI aldolase family - - - - - - - - - - - - HpcH_HpaI DYD2_k127_3508381_9 1205680.CAKO01000002_gene2549 1.225e-102 342.0 COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM amidohydrolase 2 - - - - - - - - - - - - Amidohydro_2 DYD2_k127_3508381_3 760568.Desku_3253 8.852e-126 425.0 COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,260EE@186807|Peptococcaceae 186801|Clostridia S TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM DYD2_k127_3508381_16 1499967.BAYZ01000080_gene954 9.578e-34 143.0 COG2358@1|root,COG2358@2|Bacteria 2|Bacteria G TRAP transporter, solute receptor (TAXI family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD2_k127_3508381_13 1123504.JQKD01000012_gene1279 1.109e-79 275.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2VH6T@28216|Betaproteobacteria,4ABNG@80864|Comamonadaceae 28216|Betaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 DYD2_k127_3508381_4 1123072.AUDH01000012_gene3499 5.545e-121 398.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VFXC@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_3517520_32 477228.YO5_01786 2.801e-12 74.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1Z0JR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P COG0474 Cation transport ATPase ctpF - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 DYD2_k127_3517520_0 1095769.CAHF01000014_gene3154 5.832e-191 608.0 COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,2VPEG@28216|Betaproteobacteria,472QT@75682|Oxalobacteraceae 28216|Betaproteobacteria C Protein of unknown function (DUF4080) - - - - - - - - - - - - B12-binding,DUF4080,Radical_SAM DYD2_k127_3517520_29 765912.Thimo_2745 9.478e-28 117.0 2C8BN@1|root,32RKS@2|Bacteria,1N7Z0@1224|Proteobacteria,1T0YM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glycine-zipper domain - - - - - - - - - - - - - DYD2_k127_3517520_24 1469245.JFBG01000011_gene806 4.53e-34 136.0 COG1765@1|root,COG1765@2|Bacteria,1NID1@1224|Proteobacteria 1224|Proteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD2_k127_3517520_8 1469245.JFBG01000011_gene805 4.592e-121 398.0 COG1638@1|root,COG1638@2|Bacteria,1MUJY@1224|Proteobacteria,1S63M@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP DYD2_k127_3517520_25 366394.Smed_3147 4.542e-33 141.0 COG0715@1|root,COG0715@2|Bacteria,1Q20D@1224|Proteobacteria,2VF5Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - NMT1,NMT1_2 DYD2_k127_3517520_28 1305735.JAFT01000005_gene2483 2.233e-28 130.0 COG4665@1|root,COG4665@2|Bacteria,1RBTR@1224|Proteobacteria,2U8RR@28211|Alphaproteobacteria,2PERM@252301|Oceanicola 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD2_k127_3517520_5 981384.AEYW01000001_gene1545 1.153e-147 479.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TRM1@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM DYD2_k127_3517520_14 388401.RB2150_02749 6.69e-92 329.0 COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,2TT8T@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q protocatechuate 3,4-dioxygenase, beta subunit' - - 1.13.11.1 ko:K03381 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R00817,R04258,R05299,R08114,R08115,R09134 RC00388,RC00535,RC01366 ko00000,ko00001,ko00002,ko01000 - - - Dioxygenase_C,Dioxygenase_N DYD2_k127_3517520_2 1207063.P24_04035 4.056e-169 552.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2TS7J@28211|Alphaproteobacteria,2JQWQ@204441|Rhodospirillales 204441|Rhodospirillales P PhoD-like phosphatase, N-terminal domain - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N DYD2_k127_3517520_30 1121861.KB899927_gene1536 9.243e-25 106.0 2C4KB@1|root,32YM4@2|Bacteria,1N74A@1224|Proteobacteria,2UHJ4@28211|Alphaproteobacteria,2JU0J@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD2_k127_3517520_18 443144.GM21_1101 9.018e-67 242.0 COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,42PJR@68525|delta/epsilon subdivisions,2WPBQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function (DUF2520) - - - - - - - - - - - - DUF2520,Rossmann-like DYD2_k127_3517520_9 1485544.JQKP01000001_gene1283 4.906e-107 381.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,44WA4@713636|Nitrosomonadales 28216|Betaproteobacteria L Elongator protein 3, MiaB family, Radical SAM splB - - - - - - - - - - - Radical_SAM DYD2_k127_3517520_7 105559.Nwat_2073 8.029e-124 407.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WZ4R@135613|Chromatiales 135613|Chromatiales BQ PFAM histone deacetylase superfamily - - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl DYD2_k127_3517520_11 859657.RPSI07_1012 3.016e-101 340.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VP68@28216|Betaproteobacteria,1K1EY@119060|Burkholderiaceae 28216|Betaproteobacteria C luciferase - - - - - - - - - - - - Bac_luciferase DYD2_k127_3517520_35 1453496.AT03_07005 8.467e-05 50.0 2E4IS@1|root,32ZDU@2|Bacteria,1N7N3@1224|Proteobacteria,1S6R3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phosphate starvation-inducible protein, PSIF psiF - - - - - - - - - - - PsiF_repeat DYD2_k127_3517520_16 296591.Bpro_4278 2.803e-81 278.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae 28216|Betaproteobacteria O protein-L-isoaspartate O-methyltransferase pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD2_k127_3517520_33 1166948.JPZL01000001_gene2215 8.896e-09 66.0 2A110@1|root,332M4@2|Bacteria,1N7ZV@1224|Proteobacteria,1SNFG@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3517520_17 582744.Msip34_1562 7.397e-68 234.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2VRTS@28216|Betaproteobacteria,2KMP8@206350|Nitrosomonadales 206350|Nitrosomonadales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N DYD2_k127_3517520_21 323848.Nmul_A2135 1.549e-37 146.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,373HC@32003|Nitrosomonadales 28216|Betaproteobacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 DYD2_k127_3517520_27 1198452.Jab_1c19850 5.391e-31 126.0 COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,2VTXE@28216|Betaproteobacteria,474RW@75682|Oxalobacteraceae 28216|Betaproteobacteria S CbiX cbiX - 4.99.1.3 ko:K03795 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05807 RC01012 ko00000,ko00001,ko01000 - - - CbiX DYD2_k127_3517520_23 204773.HEAR0842 2.954e-34 134.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,4744K@75682|Oxalobacteraceae 28216|Betaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase DYD2_k127_3517520_4 1163617.SCD_n00749 3.184e-151 498.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein DYD2_k127_3517520_13 1266925.JHVX01000006_gene2161 3.469e-92 307.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,371UQ@32003|Nitrosomonadales 28216|Betaproteobacteria L Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC DYD2_k127_3517520_22 743299.Acife_0588 4.488e-35 135.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,2ND87@225057|Acidithiobacillales 225057|Acidithiobacillales J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 DYD2_k127_3517520_31 314607.KB13_482 2.695e-21 93.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,1KQ4N@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 DYD2_k127_3517520_1 323848.Nmul_A2141 3.92e-181 573.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,37215@32003|Nitrosomonadales 28216|Betaproteobacteria I fatty acid desaturase ole1 - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase DYD2_k127_3517520_3 1163617.SCD_n02360 3.399e-158 512.0 COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria 28216|Betaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family rsmB_2 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N DYD2_k127_3517520_26 1485544.JQKP01000003_gene155 2.055e-31 137.0 COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria,44VTY@713636|Nitrosomonadales 28216|Betaproteobacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 DYD2_k127_3517520_15 76114.ebA655 1.534e-84 284.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,2KVYQ@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N DYD2_k127_3517520_6 1095769.CAHF01000013_gene3337 4.62e-147 486.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,4725K@75682|Oxalobacteraceae 28216|Betaproteobacteria F AIR synthase related protein, N-terminal domain purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD2_k127_3517520_20 1163617.SCD_n02352 4.836e-59 212.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria 28216|Betaproteobacteria L Belongs to the DnaA family hda - - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA DYD2_k127_3517520_12 1288494.EBAPG3_20350 2.429e-98 330.0 COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,3723W@32003|Nitrosomonadales 28216|Betaproteobacteria E TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - - - - - - - - - - HAD DYD2_k127_3517520_10 1266925.JHVX01000015_gene230 1.159e-102 343.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VK1S@28216|Betaproteobacteria,372XQ@32003|Nitrosomonadales 28216|Betaproteobacteria P FecCD transport family btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD DYD2_k127_3517520_19 1163617.SCD_n02223 1.367e-65 234.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2VRFJ@28216|Betaproteobacteria 28216|Betaproteobacteria HP ABC transporter - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran DYD2_k127_3531223_43 323848.Nmul_A2339 3.792e-69 236.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,372UG@32003|Nitrosomonadales 28216|Betaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX DYD2_k127_3531223_32 323848.Nmul_A2340 2.882e-107 350.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,371RU@32003|Nitrosomonadales 28216|Betaproteobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease DYD2_k127_3531223_14 1288494.EBAPG3_26760 1.568e-159 514.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,371ZV@32003|Nitrosomonadales 28216|Betaproteobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N DYD2_k127_3531223_35 292415.Tbd_1696 2.151e-98 327.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria 28216|Betaproteobacteria I phytoene synthase hpnC - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY DYD2_k127_3531223_22 522306.CAP2UW1_3259 2.715e-127 413.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,1KQE3@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria I Squalene/phytoene synthase hpnD - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY DYD2_k127_3531223_33 1380394.JADL01000001_gene2346 8.239e-101 334.0 COG1028@1|root,COG1028@2|Bacteria,1QWBB@1224|Proteobacteria,2U2FD@28211|Alphaproteobacteria,2JVVT@204441|Rhodospirillales 204441|Rhodospirillales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 DYD2_k127_3531223_20 631454.N177_1636 9.271e-131 428.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2TQMC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - 5.3.2.8 ko:K16514 ko00362,ko01120,map00362,map01120 - R07839 RC02426 ko00000,ko00001,ko01000 - - - PrpF DYD2_k127_3531223_21 1163617.SCD_n01778 1.58e-129 426.0 COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria 28216|Betaproteobacteria H squalene-associated FAD-dependent desaturase hpnE - 1.17.8.1 ko:K21677 - - - - ko00000,ko01000 - - - Amino_oxidase DYD2_k127_3531223_4 243160.BMA1116 6.968e-281 871.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,1K2GN@119060|Burkholderiaceae 28216|Betaproteobacteria C electron transfer flavoprotein-ubiquinone oxidoreductase etf - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8 DYD2_k127_3531223_10 153948.NAL212_1990 5.39e-187 591.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,371MS@32003|Nitrosomonadales 28216|Betaproteobacteria I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N DYD2_k127_3531223_1 1288494.EBAPG3_7590 0.0 1146.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VHS7@28216|Betaproteobacteria,3725I@32003|Nitrosomonadales 28216|Betaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 DYD2_k127_3531223_31 1123393.KB891316_gene1963 3.893e-109 368.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria,1KRBN@119069|Hydrogenophilales 119069|Hydrogenophilales I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X DYD2_k127_3531223_47 795666.MW7_2296 6.552e-55 194.0 COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,1K7QJ@119060|Burkholderiaceae 28216|Betaproteobacteria I Thioesterase superfamily protein yciA - - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT DYD2_k127_3531223_7 1266925.JHVX01000008_gene320 5.359e-231 729.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,372ME@32003|Nitrosomonadales 28216|Betaproteobacteria I AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding DYD2_k127_3531223_28 580332.Slit_1860 2.525e-111 367.0 COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2VM6G@28216|Betaproteobacteria 28216|Betaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - ko:K13775 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short DYD2_k127_3531223_41 1211115.ALIQ01000136_gene1256 4.85e-72 251.0 COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2U2T5@28211|Alphaproteobacteria,3NCKB@45404|Beijerinckiaceae 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - - ko:K15313 - - - - ko00000,ko01008 - - - ECH_1 DYD2_k127_3531223_3 1266925.JHVX01000008_gene319 1.464e-315 986.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,3724V@32003|Nitrosomonadales 28216|Betaproteobacteria I acyl-CoA dehydrogenase fadE - - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 DYD2_k127_3531223_11 404380.Gbem_3523 2.251e-184 617.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,43AN8@68525|delta/epsilon subdivisions,2X62F@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Bacterial transcriptional activator domain - - - - - - - - - - - - BTAD DYD2_k127_3531223_38 335543.Sfum_2673 4.954e-84 290.0 COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria 28221|Deltaproteobacteria S TRAP transporter T-component - - - - - - - - - - - - TAtT DYD2_k127_3531223_29 1100720.ALKN01000007_gene2915 4.603e-111 370.0 COG1638@1|root,COG1638@2|Bacteria,1PMWE@1224|Proteobacteria,2VNJI@28216|Betaproteobacteria 28216|Betaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP DYD2_k127_3531223_17 382464.ABSI01000012_gene2146 3.164e-149 494.0 COG1593@1|root,COG1593@2|Bacteria 2|Bacteria G mannitol 2-dehydrogenase activity - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM,DctQ DYD2_k127_3531223_42 1005999.GLGR_1569 1.395e-69 241.0 COG0671@1|root,COG0671@2|Bacteria,1QFZ7@1224|Proteobacteria,1S190@1236|Gammaproteobacteria 1236|Gammaproteobacteria I PAP2 superfamily - - - - - - - - - - - - PAP2_3 DYD2_k127_3531223_56 1157708.KB907466_gene659 2.045e-21 100.0 2CH9M@1|root,332CJ@2|Bacteria,1N7TS@1224|Proteobacteria,2VX3H@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3531223_2 1266925.JHVX01000001_gene2629 0.0 1092.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,37225@32003|Nitrosomonadales 28216|Betaproteobacteria IQ AMP-dependent synthetase - - - - - - - - - - - - AMP-binding,Acyltransferase,PP-binding DYD2_k127_3531223_37 1000565.METUNv1_04061 1.578e-84 292.0 COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,2KVUV@206389|Rhodocyclales 206389|Rhodocyclales C formate dehydrogenase fdhC - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Ni_hydr_CYTB DYD2_k127_3531223_5 983917.RGE_21280 9.251e-280 870.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VKSM@28216|Betaproteobacteria,1KNEK@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Fumarate reductase flavoprotein C-term frdA - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD2_k127_3531223_26 522306.CAP2UW1_0925 9.589e-121 391.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VNVE@28216|Betaproteobacteria,1KR8I@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain frdB - 1.3.5.4 ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 DYD2_k127_3531223_50 748247.AZKH_0531 5.766e-33 132.0 COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,2VTQJ@28216|Betaproteobacteria 28216|Betaproteobacteria C Fumarate reductase subunit C frdC - - ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Fumarate_red_C DYD2_k127_3531223_49 522306.CAP2UW1_0923 9.226e-42 163.0 COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2VTX9@28216|Betaproteobacteria 28216|Betaproteobacteria C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane frdD - - ko:K00247 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Fumarate_red_D DYD2_k127_3531223_9 224911.27349577 3.225e-221 694.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2TVZD@28211|Alphaproteobacteria,3JSBM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 DYD2_k127_3531223_44 257310.BB1049 1.708e-67 239.0 COG3836@1|root,COG3836@2|Bacteria,1PE5B@1224|Proteobacteria,2W9U5@28216|Betaproteobacteria,3T7EH@506|Alcaligenaceae 28216|Betaproteobacteria G Belongs to the HpcH HpaI aldolase family - - - - - - - - - - - - HpcH_HpaI DYD2_k127_3531223_6 1218084.BBJK01000075_gene5224 6.147e-232 731.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,1K5NT@119060|Burkholderiaceae 28216|Betaproteobacteria I Acyl-CoA dehydrogenase N terminal - - - ko:K20035 ko00920,map00920 - R11130 RC03363 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N DYD2_k127_3531223_24 269796.Rru_A3078 3.998e-126 410.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2TR10@28211|Alphaproteobacteria,2JPTQ@204441|Rhodospirillales 204441|Rhodospirillales C electron transfer flavoprotein, alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha DYD2_k127_3531223_30 159087.Daro_1211 5.888e-110 361.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,2KUTX@206389|Rhodocyclales 206389|Rhodocyclales C Electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF DYD2_k127_3531223_8 1163617.SCD_n01785 3.153e-226 707.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria 28216|Betaproteobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C DYD2_k127_3531223_19 1485544.JQKP01000001_gene1216 3.679e-133 433.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,44VAB@713636|Nitrosomonadales 28216|Betaproteobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N DYD2_k127_3531223_57 1158760.AQXP01000044_gene199 4.235e-20 94.0 2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD2_k127_3531223_36 1158150.KB906243_gene1739 2.581e-87 300.0 COG0518@1|root,COG0518@2|Bacteria,1MYXC@1224|Proteobacteria,1SJVW@1236|Gammaproteobacteria 1236|Gammaproteobacteria F GMP synthase (glutamine-hydrolyzing) activity - - - - - - - - - - - - - DYD2_k127_3531223_25 1163617.SCD_n01589 5.242e-124 405.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_3531223_55 1266914.ATUK01000012_gene342 9.293e-22 102.0 2FCC0@1|root,344FM@2|Bacteria,1NZRH@1224|Proteobacteria,1SRBS@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3531223_12 323848.Nmul_A2116 1.346e-171 550.0 COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,37237@32003|Nitrosomonadales 28216|Betaproteobacteria EGP PFAM Major facilitator superfamily lplT - - - - - - - - - - - MFS_1 DYD2_k127_3531223_39 1380394.JADL01000002_gene1437 5.646e-76 258.0 2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,2U9PI@28211|Alphaproteobacteria,2JT3N@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD2_k127_3531223_18 319003.Bra1253DRAFT_08097 4.976e-134 436.0 COG0655@1|root,COG0655@2|Bacteria,1MX6A@1224|Proteobacteria,2TU75@28211|Alphaproteobacteria,3JTKI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red DYD2_k127_3531223_58 1532557.JL37_05425 1.268e-12 83.0 COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2VJ6I@28216|Betaproteobacteria,3T6B9@506|Alcaligenaceae 28216|Betaproteobacteria M protein involved in outer membrane biogenesis asmA - - ko:K07289,ko:K07290 - - - - ko00000 9.B.121 - - AsmA DYD2_k127_3531223_60 1354722.JQLS01000008_gene139 4.386e-08 68.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2TVI7@28211|Alphaproteobacteria,46Q44@74030|Roseovarius 28211|Alphaproteobacteria M protein involved in outer membrane biogenesis - - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2 DYD2_k127_3531223_23 1232410.KI421426_gene1459 1.235e-126 417.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2X5J8@28221|Deltaproteobacteria,43SW4@69541|Desulfuromonadales 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD2_k127_3531223_0 1232410.KI421426_gene1458 0.0 1262.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,43U04@69541|Desulfuromonadales 28221|Deltaproteobacteria V TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family - - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD2_k127_3531223_46 640081.Dsui_1285 3.819e-58 215.0 COG2165@1|root,COG2165@2|Bacteria,1RHHG@1224|Proteobacteria,2VT5N@28216|Betaproteobacteria,2KWMN@206389|Rhodocyclales 206389|Rhodocyclales NU Prokaryotic N-terminal methylation motif - - - ko:K12285 - - - - ko00000,ko02044 - - - N_methyl DYD2_k127_3531223_53 292415.Tbd_0758 7.331e-27 117.0 COG4726@1|root,COG4726@2|Bacteria,1N9C7@1224|Proteobacteria,2VWCD@28216|Betaproteobacteria 28216|Betaproteobacteria NU Pilus assembly protein PilX - - - ko:K12286 - - - - ko00000,ko02044 - - - - DYD2_k127_3531223_34 292415.Tbd_0759 7.884e-100 373.0 COG1361@1|root,COG3420@1|root,COG1361@2|Bacteria,COG3420@2|Bacteria,1NGRY@1224|Proteobacteria,2WHER@28216|Betaproteobacteria 28216|Betaproteobacteria P Conserved repeat domain - - - ko:K12287 - - - - ko00000,ko02044 - - - Laminin_G_3 DYD2_k127_3531223_40 204773.HEAR1943 2.104e-73 260.0 COG4972@1|root,COG4972@2|Bacteria,1N0HS@1224|Proteobacteria,2VQYY@28216|Betaproteobacteria,473FM@75682|Oxalobacteraceae 28216|Betaproteobacteria NU Pilus assembly protein - - - ko:K12279 - - - - ko00000,ko02044 - - - PilM_2 DYD2_k127_3531223_54 580332.Slit_2596 8.012e-26 120.0 COG3166@1|root,COG3166@2|Bacteria,1RHH0@1224|Proteobacteria,2WB06@28216|Betaproteobacteria,44W3U@713636|Nitrosomonadales 28216|Betaproteobacteria NU Fimbrial assembly protein (PilN) - - - - - - - - - - - - PilN DYD2_k127_3531223_52 204773.HEAR1941 1.64e-28 129.0 COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,2VV3H@28216|Betaproteobacteria,474M0@75682|Oxalobacteraceae 28216|Betaproteobacteria NU carbon utilization - - - ko:K12280 - - - - ko00000,ko02044 - - - T2SSM DYD2_k127_3531223_59 1198452.Jab_2c02760 2.815e-11 72.0 2DR7A@1|root,33AIK@2|Bacteria,1NGEC@1224|Proteobacteria,2VY5Y@28216|Betaproteobacteria,4759Q@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - ko:K12281 - - - - ko00000,ko02044 - - - - DYD2_k127_3531223_13 1163617.SCD_n02671 3.452e-166 548.0 COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MVNC@1224|Proteobacteria,2VMZA@28216|Betaproteobacteria 28216|Betaproteobacteria NU type II and III secretion system protein - - - ko:K02453,ko:K12282 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - STN,Secretin,Secretin_N_2 DYD2_k127_3531223_27 1095769.CAHF01000011_gene2526 1.132e-111 368.0 COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VKIQ@28216|Betaproteobacteria,472K4@75682|Oxalobacteraceae 28216|Betaproteobacteria U AAA domain exeA2 - - ko:K02450,ko:K12283 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22 DYD2_k127_3531223_48 1095769.CAHF01000011_gene2525 2.59e-46 182.0 COG0457@1|root,COG0457@2|Bacteria,1N260@1224|Proteobacteria,2VTG6@28216|Betaproteobacteria,478VR@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tetratricopeptide repeat - - - ko:K12284 - - - - ko00000,ko02044 - - - TPR_16,TPR_19,TPR_4,TPR_8 DYD2_k127_3531223_45 1288494.EBAPG3_21760 7.861e-66 233.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,3732H@32003|Nitrosomonadales 28216|Betaproteobacteria S Phosphoribosyl transferase domain comF - - - - - - - - - - - Pribosyltran DYD2_k127_3531223_15 1266925.JHVX01000013_gene1633 2.723e-155 496.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,3729W@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM DYD2_k127_3531223_16 1288494.EBAPG3_21780 1.845e-153 494.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,372XJ@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_3531223_51 1288494.EBAPG3_21790 8.237e-29 127.0 COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,372D9@32003|Nitrosomonadales 28216|Betaproteobacteria I The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters bioH - 3.1.1.85 ko:K02170 ko00780,ko01100,map00780,map01100 M00572 R09725 RC00460,RC00461 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 DYD2_k127_3576865_13 1163617.SCD_n01692 1.029e-62 218.0 COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 DYD2_k127_3576865_23 1163617.SCD_n02150 2.543e-17 91.0 COG2863@1|root,COG2863@2|Bacteria 2|Bacteria C cytochrome - - - - - - - - - - - - Cytochrom_C DYD2_k127_3576865_25 243231.GSU0710 5.553e-13 73.0 2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,431EY@68525|delta/epsilon subdivisions,2WWFV@28221|Deltaproteobacteria,43VKI@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3576865_12 697282.Mettu_3252 9.108e-70 252.0 COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,1T2CN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glycosyl Transferase - - - - - - - - - - - - Glycos_transf_2 DYD2_k127_3576865_1 1485544.JQKP01000005_gene403 5.748e-162 539.0 COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,2VH6J@28216|Betaproteobacteria 28216|Betaproteobacteria C fad dependent oxidoreductase - - - - - - - - - - - - FAD_binding_3,Trp_halogenase DYD2_k127_3576865_11 1485544.JQKP01000005_gene404 7.878e-74 267.0 COG0251@1|root,COG0251@2|Bacteria,1NQGP@1224|Proteobacteria,2VMPK@28216|Betaproteobacteria,44WCX@713636|Nitrosomonadales 28216|Betaproteobacteria J pteridine-dependent deoxygenase - - - - - - - - - - - - Ribonuc_L-PSP DYD2_k127_3576865_19 580332.Slit_0352 5.166e-40 154.0 COG4706@1|root,COG4706@2|Bacteria,1RIH4@1224|Proteobacteria,2VT0K@28216|Betaproteobacteria,44WGM@713636|Nitrosomonadales 28216|Betaproteobacteria I dehydratase - - - - - - - - - - - - - DYD2_k127_3576865_10 269482.Bcep1808_2872 1.617e-77 278.0 COG0304@1|root,COG0304@2|Bacteria,1NP8M@1224|Proteobacteria,2VJDN@28216|Betaproteobacteria,1K4FF@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Beta-ketoacyl synthase, N-terminal domain - - - - - - - - - - - - Ketoacyl-synt_2 DYD2_k127_3576865_2 580332.Slit_0350 7.321e-158 511.0 COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,2VJR3@28216|Betaproteobacteria,44W7Z@713636|Nitrosomonadales 28216|Betaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain fabB - 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD2_k127_3576865_15 243233.MCA0921 1.329e-53 197.0 COG4123@1|root,COG4123@2|Bacteria 2|Bacteria AJ Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - Methyltransf_23,Methyltransf_25,Methyltransf_32 DYD2_k127_3576865_7 1122604.JONR01000019_gene1205 1.418e-89 304.0 COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,1S5G3@1236|Gammaproteobacteria,1XC69@135614|Xanthomonadales 135614|Xanthomonadales G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_3576865_0 580332.Slit_0368 2.172e-219 712.0 COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,44WBH@713636|Nitrosomonadales 28216|Betaproteobacteria S MMPL family - - - - - - - - - - - - MMPL DYD2_k127_3576865_18 580332.Slit_0367 3.771e-43 167.0 COG2834@1|root,COG2834@2|Bacteria,1RHYN@1224|Proteobacteria,2VSXY@28216|Betaproteobacteria,44WC9@713636|Nitrosomonadales 28216|Betaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - LolA DYD2_k127_3576865_8 580332.Slit_0366 1.154e-87 302.0 COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2VHP0@28216|Betaproteobacteria,44W9Y@713636|Nitrosomonadales 28216|Betaproteobacteria M Bacterial lipid A biosynthesis acyltransferase - - - - - - - - - - - - Lip_A_acyltrans DYD2_k127_3576865_24 580332.Slit_0365 1.091e-13 79.0 COG0764@1|root,COG0764@2|Bacteria,1N8Q8@1224|Proteobacteria,2VVQ1@28216|Betaproteobacteria,44WKG@713636|Nitrosomonadales 28216|Betaproteobacteria I FabA-like domain - - - - - - - - - - - - FabA DYD2_k127_3576865_3 580332.Slit_0364 2.516e-144 472.0 COG0318@1|root,COG0318@2|Bacteria,1MXPB@1224|Proteobacteria,2VJ3A@28216|Betaproteobacteria,44W5T@713636|Nitrosomonadales 28216|Betaproteobacteria IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C,FabA DYD2_k127_3576865_21 580332.Slit_0363 5.462e-30 127.0 COG4648@1|root,COG4648@2|Bacteria,1RII0@1224|Proteobacteria,2VSMC@28216|Betaproteobacteria,44WCB@713636|Nitrosomonadales 28216|Betaproteobacteria S membrane - - - - - - - - - - - - - DYD2_k127_3576865_22 1485544.JQKP01000003_gene224 1.573e-26 113.0 COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,2VWKA@28216|Betaproteobacteria,44WMD@713636|Nitrosomonadales 28216|Betaproteobacteria IQ Phosphopantetheine attachment site - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD2_k127_3576865_14 1380394.JADL01000001_gene2569 3.709e-62 226.0 2EDW0@1|root,32VXH@2|Bacteria,1R3JT@1224|Proteobacteria,2U03S@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3576865_4 1380394.JADL01000001_gene2570 7.569e-105 353.0 COG4783@1|root,COG4783@2|Bacteria,1NP1J@1224|Proteobacteria,2UK80@28211|Alphaproteobacteria,2JXWA@204441|Rhodospirillales 204441|Rhodospirillales S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD2_k127_3576865_20 1380394.JADL01000001_gene2571 8.808e-33 135.0 2EAQM@1|root,334SV@2|Bacteria,1N39W@1224|Proteobacteria,2UE2Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3576865_6 497321.C664_10842 1.864e-93 314.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,2KVMZ@206389|Rhodocyclales 206389|Rhodocyclales O Peptidase M48 - - - - - - - - - - - - Peptidase_M48 DYD2_k127_3576865_5 85643.Tmz1t_0493 4.017e-101 340.0 COG1988@1|root,COG1988@2|Bacteria,1R5QP@1224|Proteobacteria,2WFIE@28216|Betaproteobacteria,2KVF6@206389|Rhodocyclales 206389|Rhodocyclales S membrane-bound metal-dependent - - - ko:K07038 - - - - ko00000 - - - YdjM DYD2_k127_3576865_17 667632.KB890169_gene5035 2.622e-45 165.0 COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,2VUAP@28216|Betaproteobacteria,1K8TQ@119060|Burkholderiaceae 28216|Betaproteobacteria P Rieske-like [2Fe-2S] domain - - - ko:K05710,ko:K18087 ko00360,ko00621,ko01100,ko01120,ko01220,map00360,map00621,map01100,map01120,map01220 M00543,M00545 R05261,R05262,R05263,R05264,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske,Rieske_2 DYD2_k127_3576865_9 323848.Nmul_A0701 7.635e-82 275.0 COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2VQ83@28216|Betaproteobacteria,371PF@32003|Nitrosomonadales 28216|Betaproteobacteria O Scaffold protein Nfu/NifU N terminal - - - - - - - - - - - - Nfu_N,NifU DYD2_k127_3576865_16 323848.Nmul_A0700 1.452e-46 169.0 COG0822@1|root,COG0822@2|Bacteria,1PC9F@1224|Proteobacteria,2VS65@28216|Betaproteobacteria,372KK@32003|Nitrosomonadales 28216|Betaproteobacteria C NifU-like N terminal domain - - - ko:K04488 - - - - ko00000 - - - NifU_N DYD2_k127_361567_4 1000565.METUNv1_00113 3.852e-55 198.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VSEK@28216|Betaproteobacteria 28216|Betaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE8 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_361567_5 864051.BurJ1DRAFT_3759 2.248e-44 163.0 COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,2VVUF@28216|Betaproteobacteria 28216|Betaproteobacteria V Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 DYD2_k127_361567_1 472759.Nhal_1112 1.184e-157 501.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RN94@1236|Gammaproteobacteria,1WXKU@135613|Chromatiales 135613|Chromatiales S PFAM Radical SAM - - - - - - - - - - - - DUF3641,Fer4_12,Radical_SAM DYD2_k127_361567_0 1454004.AW11_02718 1.247e-190 606.0 COG0591@1|root,COG0591@2|Bacteria,1PKDE@1224|Proteobacteria 1224|Proteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF DYD2_k127_361567_3 1100720.ALKN01000028_gene2604 2.853e-86 307.0 COG0639@1|root,COG0639@2|Bacteria,1PXN4@1224|Proteobacteria 1224|Proteobacteria T COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - - - - - - - - - - Metallophos_2 DYD2_k127_361567_2 522306.CAP2UW1_2826 9.477e-150 484.0 COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KQAC@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C SNARE associated Golgi protein merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,SNARE_assoc DYD2_k127_362638_6 1485544.JQKP01000001_gene918 3.218e-32 134.0 COG3165@1|root,COG3165@2|Bacteria,1N314@1224|Proteobacteria,2VU2B@28216|Betaproteobacteria,44WEV@713636|Nitrosomonadales 28216|Betaproteobacteria S protein conserved in bacteria - - - ko:K03690 - - - - ko00000 - - - SCP2 DYD2_k127_362638_3 323848.Nmul_A2269 4.441e-108 354.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,372DU@32003|Nitrosomonadales 28216|Betaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran DYD2_k127_362638_4 1288494.EBAPG3_2480 5.845e-60 209.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,3734V@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 DYD2_k127_362638_2 557598.LHK_00165 1.273e-110 361.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KQ47@206351|Neisseriales 206351|Neisseriales T Transcriptional regulatory protein, C terminal phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD2_k127_362638_0 1163617.SCD_n00282 5.418e-155 501.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 DYD2_k127_362638_1 1163617.SCD_n00281 1.528e-117 398.0 2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_362638_5 1163617.SCD_n00280 7.667e-45 169.0 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria 28216|Betaproteobacteria FG Histidine triad (Hit) protein hit - - - - - - - - - - - HIT DYD2_k127_362638_7 314230.DSM3645_08086 2.711e-10 66.0 COG3608@1|root,COG3608@2|Bacteria,2IZ3P@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF2817) - - - - - - - - - - - - DUF2817 DYD2_k127_3723040_3 1123392.AQWL01000005_gene3135 6.37e-44 162.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator bigR - - - - - - - - - - - HTH_5 DYD2_k127_3723040_0 580332.Slit_2620 1.179e-225 708.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,44V6E@713636|Nitrosomonadales 28216|Betaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N DYD2_k127_3723040_2 1288494.EBAPG3_21670 7.02e-111 381.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,371NY@32003|Nitrosomonadales 28216|Betaproteobacteria D Peptidase family M23 envC - - - - - - - - - - - Peptidase_M23 DYD2_k127_3723040_1 1288494.EBAPG3_21660 1.184e-168 536.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,372E5@32003|Nitrosomonadales 28216|Betaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 DYD2_k127_3731256_12 1380391.JIAS01000001_gene2787 4.655e-06 54.0 COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,2U6ZZ@28211|Alphaproteobacteria,2JU9D@204441|Rhodospirillales 204441|Rhodospirillales S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD2_k127_3731256_13 1288298.rosmuc_01624 9.613e-05 48.0 COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,46NI3@74030|Roseovarius 28211|Alphaproteobacteria O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity ahpD - - - - - - - - - - - CMD DYD2_k127_3731256_6 34007.IT40_08720 1.309e-69 244.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,2PVYR@265|Paracoccus 28211|Alphaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 DYD2_k127_3731256_3 1125973.JNLC01000010_gene1417 7.168e-236 743.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,3JZ96@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD2_k127_3731256_8 243365.CV_0865 9.608e-60 228.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - - - - - - - - - - DLH,DUF1100,Hydrolase_4 DYD2_k127_3731256_1 1128421.JAGA01000003_gene2953 7.221e-319 1002.0 COG0366@1|root,COG0366@2|Bacteria,2NQQN@2323|unclassified Bacteria 2|Bacteria G Alpha amylase, catalytic domain - - - - - - - - - - - - Alpha-amylase DYD2_k127_3731256_4 345341.KUTG_02884 1.345e-218 698.0 COG1529@1|root,COG1529@2|Bacteria,2GIY7@201174|Actinobacteria,4DZMZ@85010|Pseudonocardiales 201174|Actinobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2,Fer2,Fer2_2 DYD2_k127_3731256_5 411902.CLOBOL_02063 7.653e-86 301.0 COG1073@1|root,COG1073@2|Bacteria,1TRSD@1239|Firmicutes 1239|Firmicutes S Belongs to the UPF0255 family - - - - - - - - - - - - DUF1100 DYD2_k127_3731256_9 589865.DaAHT2_2567 1.517e-51 192.0 COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,42VBZ@68525|delta/epsilon subdivisions,2WS0K@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Phospholipid N-methyltransferase - - - - - - - - - - - - Methyltransf_25,RrnaAD DYD2_k127_3731256_7 215803.DB30_6542 1.878e-68 240.0 COG0500@1|root,COG2226@2|Bacteria,1RC36@1224|Proteobacteria,42UDA@68525|delta/epsilon subdivisions,2WQHW@28221|Deltaproteobacteria,2YV8X@29|Myxococcales 28221|Deltaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_31 DYD2_k127_3731256_11 1121935.AQXX01000005_gene681 3.421e-28 130.0 2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3731256_2 1352941.M877_29430 3.285e-243 774.0 COG2936@1|root,COG2936@2|Bacteria,2GKZH@201174|Actinobacteria 201174|Actinobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD2_k127_3731256_10 1123393.KB891328_gene550 1.076e-40 155.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,1KRV8@119069|Hydrogenophilales 119069|Hydrogenophilales J S4 RNA-binding domain - - - - - - - - - - - - S4 DYD2_k127_3731256_0 1123368.AUIS01000004_gene140 0.0 1029.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,2NCC6@225057|Acidithiobacillales 225057|Acidithiobacillales P Cation transport ATPase (P-type) - - - - - - - - - - - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 DYD2_k127_3777712_3 1163617.SCD_n02508 2.127e-68 240.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria 28216|Betaproteobacteria H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 DYD2_k127_3777712_5 631362.Thi970DRAFT_03518 7.908e-57 205.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria,1WXQD@135613|Chromatiales 135613|Chromatiales O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran DYD2_k127_3777712_2 1288494.EBAPG3_12810 2.182e-80 274.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,371Q1@32003|Nitrosomonadales 28216|Betaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB DYD2_k127_3777712_1 1454004.AW11_02928 7.01e-122 394.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,1KQ7H@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm DYD2_k127_3777712_6 640081.Dsui_1170 2.988e-10 66.0 COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY2T@28216|Betaproteobacteria,2KXK6@206389|Rhodocyclales 206389|Rhodocyclales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes - - - ko:K02196 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.107 - - CcmD DYD2_k127_3777712_4 1288494.EBAPG3_12780 2.134e-61 219.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales 28216|Betaproteobacteria O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE - - ko:K02197 - - - - ko00000 - - - CcmE DYD2_k127_3777712_0 1121033.AUCF01000040_gene807 3.333e-192 612.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,2JR5K@204441|Rhodospirillales 204441|Rhodospirillales O COG1138 Cytochrome c biogenesis factor ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD2_k127_3953295_1 1129794.C427_4423 4.619e-33 139.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - CarboxypepD_reg,Cna_B,DUF285,MucBP,SdrD_B DYD2_k127_3953295_0 448385.sce7792 8.214e-59 218.0 COG3793@1|root,COG3793@2|Bacteria,1QZSX@1224|Proteobacteria 1224|Proteobacteria P PFAM Mo-dependent nitrogenase - - - - - - - - - - - - - DYD2_k127_3953295_2 1217718.ALOU01000010_gene980 2.259e-18 86.0 COG1538@1|root,COG1538@2|Bacteria 2|Bacteria MU efflux transmembrane transporter activity - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP DYD2_k127_3973221_16 1485544.JQKP01000002_gene1635 4.148e-09 57.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,44VXJ@713636|Nitrosomonadales 28216|Betaproteobacteria K MraZ protein, putative antitoxin-like mraZ - - ko:K03925 - - - - ko00000 - - - MraZ DYD2_k127_3973221_12 1163617.SCD_n02493 6.628e-123 401.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria 28216|Betaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 DYD2_k127_3973221_15 1120999.JONM01000006_gene2366 2.254e-28 117.0 COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria,2KS14@206351|Neisseriales 206351|Neisseriales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsL - - ko:K03586 - - - - ko00000,ko03036 - - - FtsL DYD2_k127_3973221_0 1163617.SCD_n02491 4.712e-221 704.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria 28216|Betaproteobacteria M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase DYD2_k127_3973221_6 1485544.JQKP01000002_gene1631 3.532e-161 525.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,44VE4@713636|Nitrosomonadales 28216|Betaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD2_k127_3973221_8 1163617.SCD_n02489 6.149e-153 501.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria 28216|Betaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10,6.3.2.13 ko:K01929,ko:K15792 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD2_k127_3973221_3 1288494.EBAPG3_28220 1.555e-183 579.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,372PV@32003|Nitrosomonadales 28216|Betaproteobacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 DYD2_k127_3973221_7 1163617.SCD_n02487 4.84e-154 499.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria 28216|Betaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M DYD2_k127_3973221_5 1123392.AQWL01000002_gene1861 1.786e-173 553.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,1KS5G@119069|Hydrogenophilales 119069|Hydrogenophilales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE DYD2_k127_3973221_10 323848.Nmul_A2494 3.705e-125 430.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,3728Q@32003|Nitrosomonadales 28216|Betaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 DYD2_k127_3973221_1 1163617.SCD_n02484 3.404e-213 673.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD2_k127_3973221_13 1288494.EBAPG3_28160 1.471e-109 364.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,3725K@32003|Nitrosomonadales 28216|Betaproteobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C DYD2_k127_3973221_11 1288494.EBAPG3_28150 2.086e-123 402.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,3723I@32003|Nitrosomonadales 28216|Betaproteobacteria F Cell wall formation ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N DYD2_k127_3973221_14 582744.Msip34_0464 7.107e-63 224.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,2KKS9@206350|Nitrosomonadales 206350|Nitrosomonadales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 DYD2_k127_3973221_2 1288494.EBAPG3_28130 4.458e-210 658.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,372QQ@32003|Nitrosomonadales 28216|Betaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA DYD2_k127_3973221_4 1163617.SCD_n02479 4.114e-174 554.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria 28216|Betaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin DYD2_k127_3973221_9 1163617.SCD_n02478 5.072e-148 473.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria 28216|Betaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC DYD2_k127_3973221_18 1454004.AW11_02982 4.498e-07 53.0 2ENZW@1|root,33GKQ@2|Bacteria,1NQCD@1224|Proteobacteria,2VXYX@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3973221_17 323848.Nmul_A2487 1.379e-07 59.0 COG4701@1|root,COG4701@2|Bacteria,1N8HR@1224|Proteobacteria,2VW5Y@28216|Betaproteobacteria,373FZ@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 DYD2_k127_3994214_8 883078.HMPREF9695_04349 5.295e-21 101.0 COG0251@1|root,COG0251@2|Bacteria,1RD6W@1224|Proteobacteria,2U8MG@28211|Alphaproteobacteria,3K1Y9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Endoribonuclease L-PSP rutC - - ko:K09021 ko00240,ko01100,map00240,map01100 - R09982 RC02768 ko00000,ko00001 - - - Ribonuc_L-PSP DYD2_k127_3994214_5 1205680.CAKO01000037_gene1235 2.049e-62 225.0 COG2267@1|root,COG2267@2|Bacteria,1QXIE@1224|Proteobacteria,2TXBK@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_3994214_0 443598.AUFA01000014_gene6964 4.678e-96 321.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2TRPS@28211|Alphaproteobacteria,3JREH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase MA20_40175 - 4.2.1.18,4.2.1.57 ko:K13766,ko:K13779 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R02085,R03493 RC00941,RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD2_k127_3994214_6 1123393.KB891327_gene311 1.669e-46 171.0 COG2259@1|root,COG2259@2|Bacteria,1MZC7@1224|Proteobacteria,2WANG@28216|Betaproteobacteria,1KT7P@119069|Hydrogenophilales 119069|Hydrogenophilales S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX DYD2_k127_3994214_7 335659.S23_25930 2.364e-37 144.0 COG1975@1|root,COG1975@2|Bacteria,1RI4U@1224|Proteobacteria,2U9FQ@28211|Alphaproteobacteria,3JYQ5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O XdhC and CoxI family MA20_09410 - - - - - - - - - - - XdhC_CoxI DYD2_k127_3994214_2 76114.ebA2089 2.781e-76 263.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,2KW06@206389|Rhodocyclales 206389|Rhodocyclales O XdhC Rossmann domain - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI DYD2_k127_3994214_4 76114.ebA3896 2.691e-64 229.0 COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3014) - - - - - - - - - - - - DUF3014 DYD2_k127_3994214_3 296591.Bpro_1708 1.191e-68 246.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM0F@28216|Betaproteobacteria,4AD6W@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_3994214_10 1197906.CAJQ02000053_gene4262 0.0001803 47.0 2EJ3S@1|root,33CV1@2|Bacteria,1N8ZT@1224|Proteobacteria,2UFYU@28211|Alphaproteobacteria,3K0VR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_3994214_9 1197906.CAJQ02000047_gene4072 2.016e-08 65.0 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2TSWT@28211|Alphaproteobacteria,3JT4H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EG of the drug metabolite transporter (DMT) superfamily MA20_03520 - - - - - - - - - - - EamA DYD2_k127_3994214_1 342610.Patl_1431 6.331e-90 302.0 COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,2Q0QB@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid vgb - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - SGL DYD2_k127_4005693_19 1266925.JHVX01000011_gene1483 6.45e-68 234.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,372R9@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh DYD2_k127_4005693_12 62928.azo2209 5.726e-112 366.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales 206389|Rhodocyclales O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate - 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N DYD2_k127_4005693_15 1266925.JHVX01000011_gene1486 8.882e-96 320.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,371NN@32003|Nitrosomonadales 28216|Betaproteobacteria O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat - 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans DYD2_k127_4005693_2 159087.Daro_0711 1.095e-248 793.0 COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,2KV1V@206389|Rhodocyclales 206389|Rhodocyclales P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase DYD2_k127_4005693_28 243365.CV_2041 9.06e-14 76.0 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,2VWG5@28216|Betaproteobacteria,2KS1K@206351|Neisseriales 206351|Neisseriales P cytochrome oxidase maturation protein cbb3-type ccoS - - - - - - - - - - - FixS DYD2_k127_4005693_24 596154.Alide2_3868 1.948e-36 146.0 COG0589@1|root,COG3945@1|root,COG0589@2|Bacteria,COG3945@2|Bacteria,1N12K@1224|Proteobacteria,2VUPY@28216|Betaproteobacteria,4AENF@80864|Comamonadaceae 28216|Betaproteobacteria T Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin DYD2_k127_4005693_10 1288494.EBAPG3_12710 1.149e-138 450.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2WAY9@28216|Betaproteobacteria,371NX@32003|Nitrosomonadales 28216|Betaproteobacteria O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA DYD2_k127_4005693_29 1123360.thalar_02883 9.45e-13 70.0 2ERCE@1|root,33IY3@2|Bacteria,1NNN9@1224|Proteobacteria,2UXY5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_4005693_17 1437824.BN940_02346 2.633e-84 283.0 COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2VNRT@28216|Betaproteobacteria 28216|Betaproteobacteria C cytochrome c oxidase (Subunit II) - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 DYD2_k127_4005693_1 1223521.BBJX01000002_gene2860 1.499e-257 805.0 COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2VJ1N@28216|Betaproteobacteria,4AHFT@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM Cytochrome c oxidase, subunit I cbaA - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 DYD2_k127_4005693_18 522306.CAP2UW1_1789 1.063e-83 287.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VM89@28216|Betaproteobacteria 28216|Betaproteobacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group - - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA DYD2_k127_4005693_20 522306.CAP2UW1_1788 4.722e-64 241.0 COG1999@1|root,COG1999@2|Bacteria,1N6WC@1224|Proteobacteria,2VMIP@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM electron transport protein SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD2_k127_4005693_3 522306.CAP2UW1_1324 1.877e-247 781.0 COG0543@1|root,COG1018@1|root,COG1290@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,COG1290@2|Bacteria,1MV72@1224|Proteobacteria,2VI6M@28216|Betaproteobacteria,1KR75@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C Cytochrome b(N-terminal)/b6/petB - - - - - - - - - - - - Cytochrome_B,FAD_binding_6,Fer2,NAD_binding_1 DYD2_k127_4005693_23 1454004.AW11_01051 1.081e-46 173.0 2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_4005693_9 522306.CAP2UW1_1327 8.191e-157 511.0 COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2VNFS@28216|Betaproteobacteria 28216|Betaproteobacteria C Methyl-viologen-reducing hydrogenase, delta subunit - - - - - - - - - - - - Cytochrome_B,Fer4_7,FlpD DYD2_k127_4005693_8 1223521.BBJX01000002_gene2865 4.462e-162 546.0 COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,2VKFW@28216|Betaproteobacteria,4AH9U@80864|Comamonadaceae 28216|Betaproteobacteria C Cytochrome C and Quinol oxidase polypeptide I - - - - - - - - - - - - COX1 DYD2_k127_4005693_27 323261.Noc_3040 8.728e-21 104.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1WZSA@135613|Chromatiales 135613|Chromatiales O cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA DYD2_k127_4005693_30 204773.HEAR1682 4.286e-07 59.0 COG4309@1|root,COG4309@2|Bacteria,1NHRT@1224|Proteobacteria,2VXM5@28216|Betaproteobacteria,4758A@75682|Oxalobacteraceae 28216|Betaproteobacteria S Uncharacterized conserved protein (DUF2249) - - - - - - - - - - - - DUF2249 DYD2_k127_4005693_4 1244869.H261_06576 1.351e-210 685.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,2JRZP@204441|Rhodospirillales 204441|Rhodospirillales C B12 binding domain - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM DYD2_k127_4005693_13 1266925.JHVX01000020_gene1777 4.02e-103 343.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,371WH@32003|Nitrosomonadales 28216|Betaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cysG - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase DYD2_k127_4005693_16 338969.Rfer_3196 7.522e-95 328.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,4AA8I@80864|Comamonadaceae 28216|Betaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein nosX - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE DYD2_k127_4005693_6 1123392.AQWL01000002_gene1774 1.217e-193 616.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2VH7V@28216|Betaproteobacteria 28216|Betaproteobacteria CK FMN-binding domain protein - - - - - - - - - - - - FMN_bind,Fer4_10,Fer4_5 DYD2_k127_4005693_0 292415.Tbd_0077 4.639e-284 893.0 COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,1KS6X@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome D1 heme domain - - 1.7.2.1,1.7.99.1 ko:K15864 ko00910,ko01120,map00910,map01120 M00529 R00143,R00783,R00785 RC00086,RC02797 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_D1,Cytochrome_CBB3 DYD2_k127_4005693_25 85643.Tmz1t_3728 5.537e-29 119.0 COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KXF6@206389|Rhodocyclales 206389|Rhodocyclales C Cytochrome c - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C DYD2_k127_4005693_26 1454004.AW11_03210 9.099e-26 112.0 COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,2VTXS@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III nirC - - ko:K19344 - - - - ko00000 - - - Cytochrome_CBB3 DYD2_k127_4005693_7 1121035.AUCH01000016_gene2120 1.876e-172 551.0 COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2VH1W@28216|Betaproteobacteria,2KVXA@206389|Rhodocyclales 206389|Rhodocyclales S cytochrome d1 heme nirF - - ko:K19345 - - - - ko00000 - - - Cytochrom_D1 DYD2_k127_4005693_14 292415.Tbd_0074 3.411e-101 340.0 COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,2VHP8@28216|Betaproteobacteria,1KT7B@119069|Hydrogenophilales 119069|Hydrogenophilales K COG1522 Transcriptional regulators - - - - - - - - - - - - - DYD2_k127_4005693_22 748247.AZKH_3543 6.765e-56 202.0 COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,2VSBM@28216|Betaproteobacteria,2KWF6@206389|Rhodocyclales 206389|Rhodocyclales K overlaps another CDS with the same product name nirG - - - - - - - - - - - HTH_AsnC-type DYD2_k127_4005693_21 1163617.SCD_n00375 1.352e-63 223.0 COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,2VR9X@28216|Betaproteobacteria 28216|Betaproteobacteria K transcriptional regulator AsnC family nirH - - - - - - - - - - - HTH_AsnC-type DYD2_k127_4005693_5 292415.Tbd_0071 1.892e-210 659.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria,1KSZD@119069|Hydrogenophilales 119069|Hydrogenophilales C 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_12,Radical_SAM DYD2_k127_4005693_11 292415.Tbd_0070 2.079e-137 445.0 COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,2VIU7@28216|Betaproteobacteria,1KSV4@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome D1 heme domain - - - - - - - - - - - - Cytochrom_D1,Cytochrome_CBB3 DYD2_k127_4013649_10 1123072.AUDH01000027_gene1855 2.623e-66 232.0 COG2080@1|root,COG2080@2|Bacteria,1RCC9@1224|Proteobacteria,2U3X8@28211|Alphaproteobacteria 28211|Alphaproteobacteria C 2Fe-2S -binding domain protein - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD2_k127_4013649_7 1231391.AMZF01000037_gene572 2.852e-77 267.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VHV8@28216|Betaproteobacteria 28216|Betaproteobacteria C Dehydrogenase coxM - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD2_k127_4013649_4 1205680.CAKO01000002_gene2440 2.497e-88 306.0 COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2TTF6@28211|Alphaproteobacteria 28211|Alphaproteobacteria I PFAM Acyl-CoA dehydrogenase type 2 MA20_38220 - 1.14.14.12 ko:K16047 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R09819 RC00236 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_2,Acyl-CoA_dh_N DYD2_k127_4013649_0 1123368.AUIS01000018_gene729 3.569e-214 676.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,2NC1Z@225057|Acidithiobacillales 225057|Acidithiobacillales P major facilitator superfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 DYD2_k127_4013649_8 991905.SL003B_0609 1.306e-76 273.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,4BRXZ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria V HlyD membrane-fusion protein of T1SS - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_D23 DYD2_k127_4013649_6 365046.Rta_16670 2.097e-81 284.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM3I@28216|Betaproteobacteria,4AB0D@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_4013649_12 1211115.ALIQ01000183_gene2912 2.558e-33 132.0 COG5470@1|root,COG5470@2|Bacteria,1N012@1224|Proteobacteria,2VG1G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 DYD2_k127_4013649_3 76114.ebA1984 1.859e-94 315.0 COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,2VIYW@28216|Betaproteobacteria 28216|Betaproteobacteria O Glutathione S-transferase gstP - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_3 DYD2_k127_4013649_11 493475.GARC_2752 3.452e-35 155.0 COG3540@1|root,COG3540@2|Bacteria,1NRFH@1224|Proteobacteria,1SJKC@1236|Gammaproteobacteria,469GY@72275|Alteromonadaceae 1236|Gammaproteobacteria P Alkaline phosphatase - - - - - - - - - - - - - DYD2_k127_4013649_5 1121035.AUCH01000007_gene594 6.165e-84 286.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VSX3@28216|Betaproteobacteria 28216|Betaproteobacteria V N-acetylmuramoyl-L-alanine amidase amiD - 3.5.1.28 ko:K01447,ko:K11066 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - - Amidase_2,PG_binding_1 DYD2_k127_4013649_9 1121106.JQKB01000001_gene3250 4.741e-67 240.0 COG0247@1|root,COG0247@2|Bacteria 2|Bacteria C lactate metabolic process glpC GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 ko:K00113 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - CCG,DUF3501,Fer4_8 DYD2_k127_4013649_2 765912.Thimo_2015 1.019e-110 368.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1WXTE@135613|Chromatiales 135613|Chromatiales S Pfam:UPF0118 - - - - - - - - - - - - AI-2E_transport DYD2_k127_4013649_1 395495.Lcho_1925 2.017e-196 625.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,2VKVU@28216|Betaproteobacteria,1KK05@119065|unclassified Burkholderiales 28216|Betaproteobacteria H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase DYD2_k127_4013649_14 264730.PSPPH_0251 0.0006033 49.0 COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,1RRGP@1236|Gammaproteobacteria,1Z5AI@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S bacterial OsmY and nodulation domain osmY GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - ko:K04065 - - - - ko00000 - - - BON DYD2_k127_4016451_3 1266925.JHVX01000004_gene1292 1.308e-123 398.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,372KC@32003|Nitrosomonadales 28216|Betaproteobacteria C succinate dehydrogenase fumarate reductase sdhB GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17,Fer4_8 DYD2_k127_4016451_0 580332.Slit_1839 4.217e-294 910.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,44V9G@713636|Nitrosomonadales 28216|Betaproteobacteria C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD2_k127_4016451_5 1000565.METUNv1_01115 1.99e-30 126.0 COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,2KWK5@206389|Rhodocyclales 206389|Rhodocyclales C Succinate dehydrogenase, hydrophobic - - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt DYD2_k127_4016451_4 305700.B447_15351 1.831e-36 144.0 COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,2KWKD@206389|Rhodocyclales 206389|Rhodocyclales C COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt DYD2_k127_4016451_2 1288494.EBAPG3_15790 1.03e-152 489.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,371RR@32003|Nitrosomonadales 28216|Betaproteobacteria C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N DYD2_k127_4016451_1 243365.CV_2056 4.033e-174 552.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VHJZ@28216|Betaproteobacteria,2KPG1@206351|Neisseriales 206351|Neisseriales C Belongs to the citrate synthase family prpC - 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - - Citrate_synt DYD2_k127_4045344_2 1157708.KB907450_gene6453 1.535e-111 364.0 COG3823@1|root,COG3823@2|Bacteria,1QVEC@1224|Proteobacteria,2WHF6@28216|Betaproteobacteria,4ACIU@80864|Comamonadaceae 28216|Betaproteobacteria O Glutamine cyclotransferase - - - - - - - - - - - - PQQ_2 DYD2_k127_4045344_1 1385517.N800_03190 6.768e-112 371.0 COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,1S31J@1236|Gammaproteobacteria,1X6CJ@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 DYD2_k127_4045344_4 1265505.ATUG01000001_gene4392 1.778e-41 159.0 2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales 28221|Deltaproteobacteria S DGC domain - - - - - - - - - - - - DGC DYD2_k127_4045344_3 305700.B447_00886 3.604e-71 246.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2VQAQ@28216|Betaproteobacteria,2KW2Q@206389|Rhodocyclales 206389|Rhodocyclales J Belongs to the pseudouridine synthase RsuA family - - 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 DYD2_k127_4045344_0 1288494.EBAPG3_9170 6.198e-117 381.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,371YE@32003|Nitrosomonadales 28216|Betaproteobacteria K transcriptional regulatory protein yebC - - - - - - - - - - - Transcrip_reg DYD2_k127_4049905_14 1120956.JHZK01000012_gene3642 8.836e-16 79.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2TUZ8@28211|Alphaproteobacteria,1JQ7Z@119043|Rhodobiaceae 28211|Alphaproteobacteria I Coenzyme A transferase - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD2_k127_4049905_4 795666.MW7_3365 4.661e-154 492.0 COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2VHY6@28216|Betaproteobacteria,1KFHI@119060|Burkholderiaceae 28216|Betaproteobacteria I Coenzyme A transferase - - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans DYD2_k127_4049905_0 795666.MW7_3364 3.92e-245 765.0 COG0031@1|root,COG0031@2|Bacteria,1QQKZ@1224|Proteobacteria 1224|Proteobacteria E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - - - - - - - - - - PALP DYD2_k127_4049905_1 795666.MW7_3256 4.885e-223 700.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,1K011@119060|Burkholderiaceae 28216|Betaproteobacteria F Catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway atzB - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 DYD2_k127_4049905_7 1038859.AXAU01000001_gene3731 2.899e-127 430.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,3JRC4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DUF3394,DctM DYD2_k127_4049905_12 1449063.JMLS01000024_gene3674 2.901e-52 198.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,4HB7U@91061|Bacilli,26ZXE@186822|Paenibacillaceae 91061|Bacilli S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD2_k127_4049905_2 1380355.JNIJ01000031_gene3496 9.149e-221 692.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,3JUGX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - - - - - - - - - - UbiD DYD2_k127_4049905_3 1187851.A33M_3623 7.276e-178 565.0 COG0683@1|root,COG0683@2|Bacteria,1NNXR@1224|Proteobacteria,2VEZD@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Receptor family ligand binding region - - - - - - - - - - - - Peripla_BP_6 DYD2_k127_4049905_6 1187851.A33M_3622 6.453e-139 447.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,3FE54@34008|Rhodovulum 28211|Alphaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD2_k127_4049905_5 1187851.A33M_3621 3.516e-145 482.0 COG4177@1|root,COG4177@2|Bacteria,1MXPG@1224|Proteobacteria,2TUH2@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD2_k127_4049905_9 795666.MW7_3354 5.152e-92 317.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,1K4FZ@119060|Burkholderiaceae 28216|Betaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 DYD2_k127_4049905_8 1187851.A33M_3619 1.59e-116 378.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3FD1Y@34008|Rhodovulum 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD2_k127_4049905_10 333138.LQ50_20025 3.237e-61 225.0 COG0715@1|root,COG0715@2|Bacteria,1TXP3@1239|Firmicutes,4I6PJ@91061|Bacilli,1ZM9Z@1386|Bacillus 91061|Bacilli P NMT1/THI5 like - - - - - - - - - - - - NMT1 DYD2_k127_4049905_13 1121422.AUMW01000026_gene379 9.654e-39 158.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia,265U0@186807|Peptococcaceae 186801|Clostridia E Ornithine cyclodeaminase/mu-crystallin family ocd - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD2_k127_4049905_11 266265.Bxe_B2353 2.97e-55 197.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VQCJ@28216|Betaproteobacteria,1K1CQ@119060|Burkholderiaceae 28216|Betaproteobacteria H Belongs to the UbiD family - - - - - - - - - - - - UbiD DYD2_k127_4056212_13 1385517.N800_09760 1.597e-38 154.0 COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales 135614|Xanthomonadales H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 DYD2_k127_4056212_1 1163617.SCD_n00307 1.475e-178 570.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N DYD2_k127_4056212_9 279714.FuraDRAFT_1416 4.033e-86 293.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,2KPRM@206351|Neisseriales 206351|Neisseriales M lipid A biosynthesis lauroyl acyltransferase - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD2_k127_4056212_5 1163617.SCD_n00308 6.486e-118 385.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria 28216|Betaproteobacteria M Lipid A Biosynthesis htrB - 2.3.1.241,2.3.1.242 ko:K02517,ko:K12974 ko00540,ko01100,map00540,map01100 M00060 R05146,R10906 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD2_k127_4056212_7 338963.Pcar_1256 2.172e-91 310.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales 28221|Deltaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold gnnA - - ko:K09949 - - - - ko00000 - - iAF987.Gmet_2352 GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_4056212_10 243233.MCA2592 2.753e-73 252.0 COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria,1XFA5@135618|Methylococcales 135618|Methylococcales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 DYD2_k127_4056212_14 497321.C664_16008 5.75e-37 143.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,2KWFV@206389|Rhodocyclales 206389|Rhodocyclales S CoA-binding protein - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 DYD2_k127_4056212_4 1266925.JHVX01000007_gene2363 1.507e-120 392.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,3724R@32003|Nitrosomonadales 28216|Betaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase DYD2_k127_4056212_12 1163617.SCD_n00312 9.573e-71 251.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria 28216|Betaproteobacteria S protein conserved in bacteria - - - ko:K09921 - - - - ko00000 - - - DUF484 DYD2_k127_4056212_6 580332.Slit_0146 1.98e-110 364.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,44VAD@713636|Nitrosomonadales 28216|Betaproteobacteria D Phage integrase, N-terminal SAM-like domain xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD2_k127_4056212_3 1163617.SCD_n02069 3.37e-141 459.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria 28216|Betaproteobacteria J SMART PUA domain containing protein rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM DYD2_k127_4056212_17 870187.Thini_2788 4.045e-26 108.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,4615Y@72273|Thiotrichales 72273|Thiotrichales S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic DYD2_k127_4056212_15 1288494.EBAPG3_28670 1.029e-35 142.0 COG0735@1|root,COG0735@2|Bacteria,1NPTK@1224|Proteobacteria,2VSCH@28216|Betaproteobacteria,373AU@32003|Nitrosomonadales 28216|Betaproteobacteria P Ferric uptake regulator family - - - ko:K03711 - - - - ko00000,ko03000 - - - FUR DYD2_k127_4056212_11 582744.Msip34_1703 3.452e-72 252.0 COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria,2KKCZ@206350|Nitrosomonadales 206350|Nitrosomonadales P ZIP Zinc transporter - - - ko:K16267 - - - - ko00000,ko02000 2.A.5.4.11 - - Zip DYD2_k127_4056212_16 85643.Tmz1t_3518 3.89e-33 137.0 COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,2KWVW@206389|Rhodocyclales 206389|Rhodocyclales M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD2_k127_4056212_8 1266925.JHVX01000007_gene2356 1.14e-90 311.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,3723F@32003|Nitrosomonadales 28216|Betaproteobacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR DYD2_k127_4056212_2 1163617.SCD_n00101 2.943e-155 497.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria 28216|Betaproteobacteria M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE DYD2_k127_4056212_0 1454004.AW11_01782 1.107e-249 784.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,1KPQQ@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M Penicillin-binding protein 2 mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase DYD2_k127_4143572_15 1502851.FG93_01794 9.246e-51 185.0 COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria,3JWVC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family dehH - 3.8.1.3 ko:K01561 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD2_k127_4143572_14 634452.APA01_03780 1.279e-55 206.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2U2DD@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD2_k127_4143572_3 543913.D521_0582 6.855e-163 516.0 COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2VHTM@28216|Betaproteobacteria 28216|Betaproteobacteria G gluconolactonase - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD2_k127_4143572_11 1040989.AWZU01000013_gene1643 5.439e-82 284.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3JV1H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_4143572_4 365046.Rta_15900 2.905e-144 466.0 COG1995@1|root,COG1995@2|Bacteria,1MXGJ@1224|Proteobacteria,2VISV@28216|Betaproteobacteria,4ABVP@80864|Comamonadaceae 28216|Betaproteobacteria C Belongs to the PdxA family pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA DYD2_k127_4143572_0 639283.Snov_1607 7.54e-195 619.0 COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria,3EZS5@335928|Xanthobacteraceae 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_4143572_16 1034347.CAHJ01000023_gene3288 6.266e-43 172.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,1ZC5Y@1386|Bacillus 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD2_k127_4143572_6 1121468.AUBR01000017_gene2375 2.598e-123 409.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,42FQ2@68295|Thermoanaerobacterales 186801|Clostridia H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase DYD2_k127_4143572_17 592015.HMPREF1705_00446 1.373e-34 139.0 COG0066@1|root,COG0066@2|Bacteria,3TC62@508458|Synergistetes 508458|Synergistetes E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD2_k127_4143572_7 795666.MW7_2540 7.172e-106 355.0 COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2VH1R@28216|Betaproteobacteria,1K2BQ@119060|Burkholderiaceae 28216|Betaproteobacteria M mandelate racemase muconate lactonizing catB - 4.2.1.113,5.5.1.1 ko:K01856,ko:K02549 ko00130,ko00361,ko00362,ko00364,ko00623,ko01100,ko01110,ko01120,ko01220,map00130,map00361,map00362,map00364,map00623,map01100,map01110,map01120,map01220 M00116,M00568 R04031,R05300,R05390,R06989,R08116,R09229 RC00903,RC01038,RC01053,RC01108,RC01321,RC01356 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N DYD2_k127_4143572_10 2074.JNYD01000006_gene1616 4.546e-82 282.0 COG2513@1|root,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria,4E0PY@85010|Pseudonocardiales 201174|Actinobacteria G Phosphoenolpyruvate phosphomutase - - 4.1.3.32 ko:K20454 ko00760,ko01120,map00760,map01120 - R01355 RC00286,RC01810 ko00000,ko00001,ko01000 - - - PEP_mutase DYD2_k127_4143572_2 1380391.JIAS01000018_gene1050 7.835e-187 599.0 COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria,2JS6T@204441|Rhodospirillales 204441|Rhodospirillales S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_4143572_8 1125973.JNLC01000011_gene591 4.258e-91 314.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_4143572_9 1268622.AVS7_04525 1.328e-86 297.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_4143572_5 1380394.JADL01000001_gene2481 4.695e-134 445.0 COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE PrpD family protein - - - - - - - - - - - - MmgE_PrpD DYD2_k127_4143572_1 1207063.P24_13673 2.078e-189 603.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JQSB@204441|Rhodospirillales 204441|Rhodospirillales C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_binding_2 DYD2_k127_4143572_12 269482.Bcep1808_6383 3.102e-80 297.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2VV9X@28216|Betaproteobacteria,1K8N9@119060|Burkholderiaceae 28216|Betaproteobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD2_k127_4143572_13 1380391.JIAS01000018_gene1049 2.259e-59 211.0 COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,2VFXG@28211|Alphaproteobacteria,2JRH8@204441|Rhodospirillales 204441|Rhodospirillales CE Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD2_k127_4166106_8 292415.Tbd_1151 5.328e-37 142.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,1KS7Z@119069|Hydrogenophilales 119069|Hydrogenophilales C NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD2_k127_4166106_7 228410.NE1767 3.981e-44 162.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,373AA@32003|Nitrosomonadales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD2_k127_4166106_0 323848.Nmul_A1102 1.569e-295 919.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,371N6@32003|Nitrosomonadales 28216|Betaproteobacteria C chain 5 L nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N DYD2_k127_4166106_1 1485544.JQKP01000010_gene814 6.441e-236 737.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,44VBV@713636|Nitrosomonadales 28216|Betaproteobacteria C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M DYD2_k127_4166106_3 1163617.SCD_n00952 5.082e-198 627.0 COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M DYD2_k127_4166106_6 1266925.JHVX01000006_gene2246 2.875e-58 216.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,371XG@32003|Nitrosomonadales 28216|Betaproteobacteria L NUDIX domain nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX DYD2_k127_4166106_4 323261.Noc_0335 2.279e-103 362.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WXR1@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,dCache_3 DYD2_k127_4166106_5 2340.JV46_25540 2.35e-75 263.0 COG1024@1|root,COG1024@2|Bacteria,1MUD7@1224|Proteobacteria,1RSI6@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Enoyl-CoA hydratase rpfF - - ko:K13816 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - ECH_1 DYD2_k127_4166106_2 1121035.AUCH01000022_gene3191 1.132e-219 701.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales 206389|Rhodocyclales IQ Phosphate acyltransferases - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase DYD2_k127_4273042_0 1342299.Z947_120 3.236e-215 683.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Hydrolase CocE NonD family - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD2_k127_4273042_1 760568.Desku_3253 7.513e-124 429.0 COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,260EE@186807|Peptococcaceae 186801|Clostridia S TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM DYD2_k127_4273042_2 693661.Arcve_0439 8.099e-31 137.0 COG2358@1|root,arCOG01801@2157|Archaea,2XTR3@28890|Euryarchaeota,246YE@183980|Archaeoglobi 183980|Archaeoglobi S TRAP transporter solute receptor, TAXI family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD2_k127_4374915_18 247639.MGP2080_05657 7.441e-73 255.0 COG1196@1|root,COG1196@2|Bacteria,1R4BS@1224|Proteobacteria,1S13B@1236|Gammaproteobacteria,1J7UD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D von Willebrand factor (VWF) type A domain - - - - - - - - - - - - VWA_2 DYD2_k127_4374915_16 876044.IMCC3088_857 6.032e-94 324.0 COG2304@1|root,COG2304@2|Bacteria,1QBPM@1224|Proteobacteria,1RQIU@1236|Gammaproteobacteria,1J4PZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Secreted protein, containing von Willebrand factor (VWF) type - - - - - - - - - - - - - DYD2_k127_4374915_21 522306.CAP2UW1_2891 2.684e-58 214.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VIN1@28216|Betaproteobacteria,1KR64@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria ET PFAM extracellular solute-binding protein family 3 aapJ - - ko:K02030,ko:K09969,ko:K10001 ko02010,ko02020,map02010,map02020 M00230,M00232,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 DYD2_k127_4374915_1 1095769.CAHF01000011_gene2142 1.78e-218 698.0 COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,472S7@75682|Oxalobacteraceae 28216|Betaproteobacteria P TonB dependent receptor yncD - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD2_k127_4374915_11 420324.KI912077_gene8198 1.354e-118 386.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,1JS1W@119045|Methylobacteriaceae 28211|Alphaproteobacteria IQ TIGRFAM 3-hydroxybutyrate dehydrogenase bdhA - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 DYD2_k127_4374915_6 1366050.N234_27775 3.841e-161 517.0 COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,1K1WI@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase DYD2_k127_4374915_27 292415.Tbd_2127 3.724e-19 94.0 COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria,1KTG0@119069|Hydrogenophilales 119069|Hydrogenophilales H ThiS family - - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD2_k127_4374915_7 580332.Slit_0409 6.61e-137 439.0 COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,44VMJ@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG DYD2_k127_4374915_14 522306.CAP2UW1_0942 1.647e-102 338.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,1KQKQ@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 DYD2_k127_4374915_4 1211115.ALIQ01000043_gene2962 1.631e-164 532.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,3NARR@45404|Beijerinckiaceae 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme cysB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_4374915_22 323098.Nwi_0207 2.74e-54 208.0 COG2242@1|root,COG2242@2|Bacteria,1QW6F@1224|Proteobacteria,2TWPP@28211|Alphaproteobacteria,3JV9N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Methyltransf_21 DYD2_k127_4374915_5 580332.Slit_0405 1.38e-163 524.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,44V6C@713636|Nitrosomonadales 28216|Betaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound hemN2 - - - - - - - - - - - HemN_C,Radical_SAM DYD2_k127_4374915_19 267608.RSc2160 2.599e-72 263.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,1K2WW@119060|Burkholderiaceae 28216|Betaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like DYD2_k127_4374915_13 1163617.SCD_n00517 7.85e-106 347.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria 28216|Betaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C DYD2_k127_4374915_15 1288494.EBAPG3_7270 1.215e-98 330.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,371PU@32003|Nitrosomonadales 28216|Betaproteobacteria S Domain of unknown function (DUF1732) yicC - - - - - - - - - - - DUF1732,YicC_N DYD2_k127_4374915_17 580332.Slit_0400 2.78e-73 252.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,44VSD@713636|Nitrosomonadales 28216|Betaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin DYD2_k127_4374915_26 522306.CAP2UW1_0931 1.516e-25 108.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,1KQ5S@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 DYD2_k127_4374915_0 1163617.SCD_n00511 0.0 1035.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria 28216|Betaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS DYD2_k127_4374915_30 264730.PSPPH_4291 8.695e-08 57.0 2EGDM@1|root,33A5H@2|Bacteria,1NJMK@1224|Proteobacteria,1SIKC@1236|Gammaproteobacteria,1Z80E@136849|Pseudomonas syringae group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_4374915_29 743299.Acife_3011 7.201e-12 69.0 2AQ9Z@1|root,31FFX@2|Bacteria,1QCZX@1224|Proteobacteria,1T8UB@1236|Gammaproteobacteria,2NDFE@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - DYD2_k127_4374915_25 640081.Dsui_2362 2.35e-34 142.0 COG3133@1|root,COG3133@2|Bacteria,1N18D@1224|Proteobacteria,2VU4M@28216|Betaproteobacteria 28216|Betaproteobacteria M PFAM 17 kDa surface antigen - - - - - - - - - - - - Rick_17kDa_Anti DYD2_k127_4374915_3 1288494.EBAPG3_22130 1.036e-186 593.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,372E7@32003|Nitrosomonadales 28216|Betaproteobacteria T Sigma-54 interaction domain yfhA - - ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD2_k127_4374915_10 1123368.AUIS01000005_gene447 2.981e-126 419.0 COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,2NBSM@225057|Acidithiobacillales 225057|Acidithiobacillales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD2_k127_4374915_23 1163617.SCD_n00578 2.99e-41 163.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria 28216|Betaproteobacteria Q toluene tolerance family protein ttg2D - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD2_k127_4374915_12 756067.MicvaDRAFT_2865 7.767e-107 357.0 COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7N7@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 DYD2_k127_4374915_9 1298867.AUES01000089_gene2973 7.101e-134 439.0 COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,3K2G8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Malate/L-lactate dehydrogenase - - - - - - - - - - - - Ldh_2 DYD2_k127_4374915_24 460265.Mnod_4142 3.7e-38 147.0 COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,2U728@28211|Alphaproteobacteria,1JUHH@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase mce - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 DYD2_k127_4374915_8 1382356.JQMP01000001_gene1074 6.745e-136 443.0 COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,27YZQ@189775|Thermomicrobia 189775|Thermomicrobia C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD2_k127_4374915_20 101510.RHA1_ro11181 1.74e-65 235.0 COG0447@1|root,COG0447@2|Bacteria,2HGHM@201174|Actinobacteria,4FZY1@85025|Nocardiaceae 201174|Actinobacteria H Enoyl-CoA hydratase/isomerase - - 4.1.3.36 ko:K01661,ko:K07536 ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220 M00116,M00540 R05592,R07263 RC01429,RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD2_k127_4374915_2 1125973.JNLC01000010_gene1411 7.366e-191 601.0 COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,3JQQG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - - - - - - - - - - Abhydrolase_6,DUF1100,Peptidase_S9 DYD2_k127_4387504_6 1207063.P24_10011 2.214e-82 276.0 COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2TQYY@28211|Alphaproteobacteria,2JRNC@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD2_k127_4387504_7 1054213.HMPREF9946_02869 3.157e-77 269.0 COG0596@1|root,COG0596@2|Bacteria,1P092@1224|Proteobacteria,2UV5T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_4387504_0 288000.BBta_5810 7.249e-263 818.0 COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,3JT6H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Malic enzyme, NAD binding domain MA20_02490 - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic DYD2_k127_4387504_5 1123072.AUDH01000001_gene2811 1.863e-83 286.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,2JS3C@204441|Rhodospirillales 204441|Rhodospirillales G Belongs to the HpcH HpaI aldolase family - - 2.7.7.38,4.1.2.52 ko:K00979,ko:K02510 ko00350,ko00540,ko01100,ko01120,map00350,map00540,map01100,map01120 M00063 R01645,R01647,R03351,R11396 RC00152,RC00307,RC00572,RC00574,RC00910,RC03057 ko00000,ko00001,ko00002,ko01000,ko01005 - - - HpcH_HpaI DYD2_k127_4387504_4 196367.JNFG01000007_gene6725 1.608e-113 379.0 COG0654@1|root,COG0654@2|Bacteria,1QXV0@1224|Proteobacteria,2VN0N@28216|Betaproteobacteria,1K0XG@119060|Burkholderiaceae 28216|Betaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 DYD2_k127_4387504_1 113395.AXAI01000013_gene6754 8.054e-197 632.0 COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TS3K@28211|Alphaproteobacteria,3JUFH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family MA20_06195 - 4.1.1.7 ko:K01576 ko00627,ko01120,map00627,map01120 - R01764,R02672 RC00595 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_4387504_8 397945.Aave_3268 3.427e-63 225.0 COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2VJ7W@28216|Betaproteobacteria,4ADUX@80864|Comamonadaceae 28216|Betaproteobacteria P extracellular solute-binding protein, family 1 - - 5.3.3.7 ko:K22003 ko00660,map00660 - R02244 RC00668 ko00000,ko00001,ko01000 - - - SBP_bac_11 DYD2_k127_4387504_3 1123073.KB899243_gene722 1.533e-167 535.0 COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,1RMY2@1236|Gammaproteobacteria,1XDBK@135614|Xanthomonadales 135614|Xanthomonadales EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 DYD2_k127_4387504_9 319003.Bra1253DRAFT_04300 8.34e-61 218.0 COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2U1JI@28211|Alphaproteobacteria,3JUZJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - 5.3.3.7 ko:K02020,ko:K22003 ko00660,ko02010,map00660,map02010 M00189 R02244 RC00668 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - SBP_bac_11 DYD2_k127_4387504_10 1121033.AUCF01000026_gene2996 7.303e-12 68.0 COG2197@1|root,COG2197@2|Bacteria,1R2TM@1224|Proteobacteria,2TU4S@28211|Alphaproteobacteria,2JUFZ@204441|Rhodospirillales 204441|Rhodospirillales T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD2_k127_4387504_2 522306.CAP2UW1_4250 2.021e-169 544.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2WGNM@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Sigma54_activat DYD2_k127_4392985_9 1157708.KB907452_gene3680 4.603e-74 259.0 COG4948@1|root,COG4948@2|Bacteria,1R85F@1224|Proteobacteria,2W04F@28216|Betaproteobacteria,4AH7P@80864|Comamonadaceae 28216|Betaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD2_k127_4392985_13 986075.CathTA2_1193 4.797e-64 240.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HC2S@91061|Bacilli 91061|Bacilli C Acyl-CoA dehydrogenase, N-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_4392985_3 398527.Bphyt_0616 2.436e-150 488.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VMYW@28216|Betaproteobacteria,1K1RG@119060|Burkholderiaceae 28216|Betaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD2_k127_4392985_1 196367.JNFG01000023_gene8189 1.507e-176 566.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKWF@28216|Betaproteobacteria,1K5CD@119060|Burkholderiaceae 28216|Betaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_4392985_8 1469245.JFBG01000037_gene1851 5.043e-80 270.0 COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,1S43F@1236|Gammaproteobacteria 1236|Gammaproteobacteria I dehydratase - - 4.2.1.56 ko:K18290 ko00660,map00660 - R02491 RC00730 ko00000,ko00001,ko01000 - - - MaoC_dehydratas DYD2_k127_4392985_4 1121861.KB899918_gene3295 1.657e-146 495.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,2JTNS@204441|Rhodospirillales 204441|Rhodospirillales S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_4392985_20 365046.Rta_19910 1.308e-17 97.0 COG0515@1|root,COG0515@2|Bacteria 365046.Rta_19910|- KLT protein kinase activity - - - - - - - - - - - - - DYD2_k127_4392985_7 395494.Galf_1181 6.384e-98 334.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales 28216|Betaproteobacteria KLT PFAM Serine threonine-protein kinase-like domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PEGA,Pkinase DYD2_k127_4392985_5 1163617.SCD_n00989 2.559e-119 389.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria 28216|Betaproteobacteria Q abc transporter ttg2A - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD2_k127_4392985_19 472759.Nhal_3516 6.966e-19 91.0 2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,1SGAI@1236|Gammaproteobacteria,1WZTM@135613|Chromatiales 135613|Chromatiales S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N DYD2_k127_4392985_21 65093.PCC7418_0099 5.456e-14 74.0 COG1723@1|root,COG1723@2|Bacteria,1G40I@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Uncharacterised ACR, YagE family COG1723 - - - - - - - - - - - - DUF155 DYD2_k127_4392985_10 640511.BC1002_5960 2.755e-72 250.0 COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,2VQJQ@28216|Betaproteobacteria,1KCYS@119060|Burkholderiaceae 28216|Betaproteobacteria S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans DYD2_k127_4392985_11 1120980.JQKH01000043_gene1301 5.637e-71 246.0 COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,2VTBI@28216|Betaproteobacteria 28216|Betaproteobacteria M D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - VanY DYD2_k127_4392985_14 640081.Dsui_0332 2.124e-61 215.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,2KWG3@206389|Rhodocyclales 206389|Rhodocyclales J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 DYD2_k127_4392985_2 153948.NAL212_1160 3.217e-158 509.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,372HG@32003|Nitrosomonadales 28216|Betaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L DYD2_k127_4392985_6 292415.Tbd_0429 3.221e-101 333.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,1KS57@119069|Hydrogenophilales 119069|Hydrogenophilales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 DYD2_k127_4392985_12 265072.Mfla_0303 2.366e-68 233.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,2KMK2@206350|Nitrosomonadales 206350|Nitrosomonadales J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 DYD2_k127_4392985_16 640081.Dsui_0336 1.858e-52 188.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,2KWBI@206389|Rhodocyclales 206389|Rhodocyclales J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 DYD2_k127_4392985_22 338969.Rfer_4221 5.058e-11 66.0 COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria,4AFV9@80864|Comamonadaceae 28216|Betaproteobacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 DYD2_k127_4392985_17 1288494.EBAPG3_30010 1.254e-35 143.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,373F5@32003|Nitrosomonadales 28216|Betaproteobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a DYD2_k127_4392985_0 640081.Dsui_0339 1.788e-223 698.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,2KVBF@206389|Rhodocyclales 206389|Rhodocyclales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY DYD2_k127_4392985_15 580332.Slit_0786 2.239e-56 201.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,44VVB@713636|Nitrosomonadales 28216|Betaproteobacteria J Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A DYD2_k127_4392985_18 580332.Slit_0785 2.101e-20 93.0 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,44W34@713636|Nitrosomonadales 28216|Betaproteobacteria J Ribosomal protein L30p/L7e rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 DYD2_k127_4430686_1 631454.N177_3084 2.662e-141 454.0 COG2267@1|root,COG2267@2|Bacteria,1MV7P@1224|Proteobacteria,2TSQ8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Hydrolase_4 DYD2_k127_4430686_0 1392838.AWNM01000097_gene171 5.764e-169 541.0 COG1960@1|root,COG1960@2|Bacteria,1Q9M3@1224|Proteobacteria,2WATR@28216|Betaproteobacteria,3T6Q4@506|Alcaligenaceae 28216|Betaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_4430686_3 1380394.JADL01000003_gene5080 1.1e-85 296.0 COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,2JRVV@204441|Rhodospirillales 204441|Rhodospirillales O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD2_k127_4430686_2 795666.MW7_2512 5.678e-95 317.0 COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2VNXU@28216|Betaproteobacteria,1K116@119060|Burkholderiaceae 28216|Betaproteobacteria IQ short-chain dehydrogenase - - - - - - - - - - - - adh_short,adh_short_C2 DYD2_k127_4430686_5 1532557.JL37_16760 6.619e-53 202.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,3T4SG@506|Alcaligenaceae 28216|Betaproteobacteria E COG0520 Selenocysteine lyase - - - - - - - - - - - - Aminotran_5 DYD2_k127_4430686_6 90814.KL370891_gene747 4.194e-30 123.0 2BZMS@1|root,32Z9B@2|Bacteria,1NCFD@1224|Proteobacteria,1SPFN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3467) - - - - - - - - - - - - DUF3467 DYD2_k127_4430686_4 1163617.SCD_n02120 5.945e-61 213.0 COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,2VT6I@28216|Betaproteobacteria 28216|Betaproteobacteria K Belongs to the Fur family - - - ko:K09826 - - - - ko00000,ko03000 - - - FUR DYD2_k127_4430686_7 1485544.JQKP01000002_gene1376 1.401e-17 93.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,44V4V@713636|Nitrosomonadales 28216|Betaproteobacteria NU Neisseria PilC beta-propeller domain pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC DYD2_k127_444985_4 292415.Tbd_0963 2.164e-102 338.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,1KRKH@119069|Hydrogenophilales 119069|Hydrogenophilales GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase DYD2_k127_444985_3 1163617.SCD_n01040 2.165e-117 387.0 COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria 28216|Betaproteobacteria M Bifunctional protein rfaE - 2.7.1.167,2.7.7.70 ko:K03272,ko:K21344 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB DYD2_k127_444985_5 1163617.SCD_n01038 6.212e-88 299.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase DYD2_k127_444985_2 1163617.SCD_n01037 1.18e-163 525.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria 28216|Betaproteobacteria G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_7 DYD2_k127_444985_9 1163617.SCD_n01036 3.341e-21 97.0 COG5416@1|root,COG5416@2|Bacteria 2|Bacteria FG Lipopolysaccharide assembly protein A domain lapA - - ko:K08992 - - - - ko00000 - - - LapA_dom DYD2_k127_444985_8 1288494.EBAPG3_23290 1.035e-46 169.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,373DE@32003|Nitrosomonadales 28216|Betaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD - - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD2_k127_444985_0 323848.Nmul_A2069 7.189e-307 946.0 COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,372RZ@32003|Nitrosomonadales 28216|Betaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 DYD2_k127_444985_6 1266925.JHVX01000006_gene2097 3.703e-72 250.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2VQ2F@28216|Betaproteobacteria,372WR@32003|Nitrosomonadales 28216|Betaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin DYD2_k127_444985_1 519989.ECTPHS_08261 4.611e-185 588.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales 135613|Chromatiales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase DYD2_k127_444985_7 1163617.SCD_n01031 1.419e-64 227.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria 28216|Betaproteobacteria E Prephenate dehydrogenase tyrA - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH DYD2_k127_4452787_29 1410620.SHLA_17c000780 1.321e-28 120.0 COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2U16Z@28211|Alphaproteobacteria,4BDVS@82115|Rhizobiaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 DYD2_k127_4452787_11 1157708.KB907450_gene6453 2.183e-110 367.0 COG3823@1|root,COG3823@2|Bacteria,1QVEC@1224|Proteobacteria,2WHF6@28216|Betaproteobacteria,4ACIU@80864|Comamonadaceae 28216|Betaproteobacteria O Glutamine cyclotransferase - - - - - - - - - - - - PQQ_2 DYD2_k127_4452787_0 296591.Bpro_0081 2.448e-189 598.0 COG0745@1|root,COG0745@2|Bacteria,1MX29@1224|Proteobacteria,2VJV7@28216|Betaproteobacteria,4ACJB@80864|Comamonadaceae 28216|Betaproteobacteria KT RESPONSE REGULATOR receiver - - - - - - - - - - - - - DYD2_k127_4452787_4 1038859.AXAU01000010_gene1766 1.544e-160 508.0 COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria,3JX2A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_4452787_25 479434.Sthe_2989 7.033e-44 175.0 COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi 2|Bacteria EGP Major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_3 DYD2_k127_4452787_15 1380394.JADL01000001_gene2257 2.651e-91 314.0 COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,2U4JI@28211|Alphaproteobacteria,2JUE6@204441|Rhodospirillales 204441|Rhodospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_4452787_30 1031711.RSPO_c01820 2.475e-10 72.0 COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,1K3IG@119060|Burkholderiaceae 28216|Betaproteobacteria S Pfam Ankyrin arp3 - - ko:K06867 - - - - ko00000 - - - Ank_2,Ank_3,Ank_4,Ank_5 DYD2_k127_4452787_2 1266925.JHVX01000003_gene534 2.617e-166 529.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,372PH@32003|Nitrosomonadales 28216|Betaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C DYD2_k127_4452787_22 292415.Tbd_0389 4.144e-64 233.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,1KRJD@119069|Hydrogenophilales 119069|Hydrogenophilales J Peptidyl-tRNA hydrolase - - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro DYD2_k127_4452787_20 261292.Nit79A3_3455 6.798e-65 230.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,37239@32003|Nitrosomonadales 28216|Betaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C DYD2_k127_4452787_5 1163617.SCD_n02621 1.285e-156 499.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria 28216|Betaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N DYD2_k127_4452787_12 1163617.SCD_n02623 2.663e-102 344.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE - 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD2_k127_4452787_28 243365.CV_4060 8.759e-32 133.0 COG3017@1|root,COG3017@2|Bacteria,1PW08@1224|Proteobacteria,2VQDJ@28216|Betaproteobacteria,2KR0A@206351|Neisseriales 206351|Neisseriales M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein lolB - - ko:K02494 - - - - ko00000 - - - LolB DYD2_k127_4452787_1 1163617.SCD_n02625 1.302e-178 580.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria 28216|Betaproteobacteria H SMART Tetratricopeptide domain protein - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 DYD2_k127_4452787_10 265072.Mfla_0682 2.324e-111 370.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VJ2B@28216|Betaproteobacteria,2KM5I@206350|Nitrosomonadales 206350|Nitrosomonadales V PFAM ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 DYD2_k127_4452787_21 1163617.SCD_n02627 1.799e-64 229.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,2VRRA@28216|Betaproteobacteria 28216|Betaproteobacteria N ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 DYD2_k127_4452787_7 1163617.SCD_n02628 8.372e-143 466.0 COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,2VMDE@28216|Betaproteobacteria 28216|Betaproteobacteria N transport system - - - - - - - - - - - - ABC_transp_aux DYD2_k127_4452787_24 1163617.SCD_n02629 1.783e-47 183.0 2E2GR@1|root,32XKS@2|Bacteria,1N41X@1224|Proteobacteria,2VUN3@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 DYD2_k127_4452787_13 1163617.SCD_n02630 9.376e-102 337.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria 28216|Betaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD2_k127_4452787_26 1348657.M622_07005 1.357e-43 160.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,2KX13@206389|Rhodocyclales 206389|Rhodocyclales C Ferredoxin - - - - - - - - - - - - Fer4 DYD2_k127_4452787_18 153948.NAL212_0452 2.649e-70 244.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,37305@32003|Nitrosomonadales 28216|Betaproteobacteria F Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD2_k127_4452787_23 1288494.EBAPG3_9250 8.779e-59 209.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,37364@32003|Nitrosomonadales 28216|Betaproteobacteria L Conserved hypothetical protein 95 rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 DYD2_k127_4452787_6 1163617.SCD_n02636 2.023e-156 506.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria 28216|Betaproteobacteria S Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD2_k127_4452787_3 1266925.JHVX01000011_gene1518 7.4e-165 531.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,371KY@32003|Nitrosomonadales 28216|Betaproteobacteria S PFAM Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD2_k127_4452787_8 582744.Msip34_1923 2.431e-126 411.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,2KKEC@206350|Nitrosomonadales 206350|Nitrosomonadales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N DYD2_k127_4452787_17 640081.Dsui_1023 7.218e-88 298.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,2KVKB@206389|Rhodocyclales 206389|Rhodocyclales D cell division ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran DYD2_k127_4452787_16 1485544.JQKP01000001_gene1195 2.815e-88 301.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,44VHS@713636|Nitrosomonadales 28216|Betaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX DYD2_k127_4452787_9 323848.Nmul_A2741 6.576e-121 394.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,3723K@32003|Nitrosomonadales 28216|Betaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 DYD2_k127_4452787_19 204773.HEAR2909 7.694e-69 239.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,473BA@75682|Oxalobacteraceae 28216|Betaproteobacteria S Involved in biogenesis of respiratory and photosynthetic systems senC - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD2_k127_4452787_14 1131553.JIBI01000002_gene1819 1.105e-98 325.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,3724X@32003|Nitrosomonadales 28216|Betaproteobacteria H Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA DYD2_k127_4452787_27 1266925.JHVX01000016_gene191 2.002e-33 130.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,3724X@32003|Nitrosomonadales 28216|Betaproteobacteria H Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA DYD2_k127_4519080_17 94624.Bpet0051 1.521e-80 279.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T6GH@506|Alcaligenaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_4519080_5 1007105.PT7_1573 1.045e-144 466.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria 28216|Betaproteobacteria G TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - - - - - - - - - - DctP DYD2_k127_4519080_21 1207063.P24_03845 5.382e-43 164.0 COG3090@1|root,COG3090@2|Bacteria,1N0N7@1224|Proteobacteria,2U65H@28211|Alphaproteobacteria,2JX9C@204441|Rhodospirillales 204441|Rhodospirillales G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD2_k127_4519080_1 1479235.KK366039_gene1628 2.131e-177 564.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria G TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM DYD2_k127_4519080_11 1384056.N787_04435 1.786e-103 348.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RVZ6@1236|Gammaproteobacteria,1XCIP@135614|Xanthomonadales 135614|Xanthomonadales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - - - - - - - - - - SUA5,Sua5_yciO_yrdC DYD2_k127_4519080_7 556268.OFAG_00241 2.444e-132 428.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,472XW@75682|Oxalobacteraceae 28216|Betaproteobacteria F SAICAR synthetase purC GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt DYD2_k127_4519080_20 580332.Slit_0026 1.095e-65 229.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,44VPK@713636|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC DYD2_k127_4519080_9 1125973.JNLC01000011_gene602 1.279e-129 428.0 COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,3JW76@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_4519080_2 1247726.MIM_c41120 3.424e-177 562.0 COG1960@1|root,COG1960@2|Bacteria,1MX17@1224|Proteobacteria,2VM2C@28216|Betaproteobacteria,3T6AI@506|Alcaligenaceae 28216|Betaproteobacteria C Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_4519080_0 1121106.JQKB01000005_gene2227 2.289e-210 675.0 COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1042 Acyl-CoA synthetase (NDP forming) - - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD2_k127_4519080_4 1268622.AVS7_00270 5.498e-152 493.0 COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VNJN@28216|Betaproteobacteria,4ACBA@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM MmgE PrpD family protein - - - - - - - - - - - - MmgE_PrpD DYD2_k127_4519080_15 596154.Alide2_3931 2.817e-86 297.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_4519080_18 56107.Cylst_0137 1.18e-78 266.0 COG1225@1|root,COG1225@2|Bacteria,1GJ4M@1117|Cyanobacteria,1HQDP@1161|Nostocales 1117|Cyanobacteria O Redoxin - - - - - - - - - - - - Redoxin DYD2_k127_4519080_3 580332.Slit_1439 2.945e-175 556.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,44VKT@713636|Nitrosomonadales 28216|Betaproteobacteria E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 DYD2_k127_4519080_6 1123024.AUII01000007_gene4798 4.344e-135 440.0 COG1960@1|root,COG1960@2|Bacteria,2GJ7S@201174|Actinobacteria,4E1DY@85010|Pseudonocardiales 201174|Actinobacteria I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,Thioesterase DYD2_k127_4519080_16 1123023.JIAI01000031_gene4074 2.06e-84 293.0 COG1960@1|root,COG1960@2|Bacteria,2GUCE@201174|Actinobacteria 201174|Actinobacteria I acyl-CoA dehydrogenase - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N DYD2_k127_4519080_10 375286.mma_1291 1.879e-113 382.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VJTU@28216|Betaproteobacteria,477DI@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC DYD2_k127_4519080_13 76114.c2A174 9.483e-97 322.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,2KVEY@206389|Rhodocyclales 206389|Rhodocyclales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD2_k127_4519080_19 1121033.AUCF01000001_gene2030 3.034e-77 269.0 COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales 204441|Rhodospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_4519080_14 1157708.KB907478_gene1212 3.527e-89 302.0 COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2W052@28216|Betaproteobacteria 28216|Betaproteobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_4519080_12 331869.BAL199_27166 7.031e-101 337.0 COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria 28211|Alphaproteobacteria S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_4519080_8 686340.Metal_2577 8.284e-132 428.0 COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1XE2N@135618|Methylococcales 135618|Methylococcales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase DYD2_k127_4537443_6 1366050.N234_22440 1.21e-79 277.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP82@28216|Betaproteobacteria,1KD4A@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_4537443_10 1304883.KI912532_gene1360 7.24e-64 223.0 COG3108@1|root,COG3108@2|Bacteria 2|Bacteria S Peptidase M15 - - - ko:K03791 - - - - ko00000 - GH19 - Peptidase_M15_3 DYD2_k127_4537443_13 194867.ALBQ01000011_gene267 9.579e-54 194.0 COG1917@1|root,COG1917@2|Bacteria,1R5IE@1224|Proteobacteria,2U1JF@28211|Alphaproteobacteria,2KEB9@204457|Sphingomonadales 204457|Sphingomonadales S Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_4537443_7 864073.HFRIS_000695 1.285e-75 263.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VTUV@28216|Betaproteobacteria 28216|Betaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.8 ko:K04101 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigB DYD2_k127_4537443_19 1298858.AUEL01000011_gene5499 1.11e-07 59.0 COG2259@1|root,COG2259@2|Bacteria,1NDJF@1224|Proteobacteria,2UFHM@28211|Alphaproteobacteria,43KVK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX DYD2_k127_4537443_5 1380394.JADL01000008_gene3603 2.138e-81 282.0 COG2421@1|root,COG2421@2|Bacteria,1MXKY@1224|Proteobacteria,2TSVA@28211|Alphaproteobacteria,2JR7H@204441|Rhodospirillales 204441|Rhodospirillales C Acetamidase/Formamidase family - - - - - - - - - - - - FmdA_AmdA DYD2_k127_4537443_8 1123368.AUIS01000006_gene572 1.513e-72 250.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1RSBH@1236|Gammaproteobacteria,2NCEE@225057|Acidithiobacillales 225057|Acidithiobacillales S SOS response associated peptidase (SRAP) - - - - - - - - - - - - SRAP DYD2_k127_4537443_17 1379698.RBG1_1C00001G1780 1.869e-16 85.0 COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria 2|Bacteria O peptidase U32 yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C DYD2_k127_4537443_15 1123060.JONP01000024_gene2535 1.004e-41 157.0 COG0599@1|root,COG0599@2|Bacteria,1RAV9@1224|Proteobacteria,2U5V1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD2_k127_4537443_1 1134474.O59_000362 1.399e-198 635.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1FFVJ@10|Cellvibrio 1236|Gammaproteobacteria V hmm pf00005 draA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD2_k127_4537443_14 1205680.CAKO01000037_gene1307 9.279e-44 166.0 COG1546@1|root,COG1546@2|Bacteria,1RHXH@1224|Proteobacteria,2UACN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the CinA family MA20_19320 - - - - - - - - - - - CinA DYD2_k127_4537443_4 1211115.ALIQ01000238_gene3256 7.265e-93 312.0 COG2242@1|root,COG2242@2|Bacteria,1R0I9@1224|Proteobacteria,2TZR6@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD2_k127_4537443_2 1410620.SHLA_38c000530 5.459e-198 623.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,4B9XR@82115|Rhizobiaceae 28211|Alphaproteobacteria I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_4537443_12 543728.Vapar_0801 1.825e-57 224.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJCY@28216|Betaproteobacteria,4ABM4@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_4537443_9 395494.Galf_0383 3.299e-66 237.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2W96D@28216|Betaproteobacteria,44WDI@713636|Nitrosomonadales 28216|Betaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin DYD2_k127_4537443_16 935863.AWZR01000002_gene807 9.513e-31 131.0 COG0607@1|root,COG0607@2|Bacteria,1MZG3@1224|Proteobacteria,1S7KP@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Rhodanese-like domain - - - - - - - - - - - - Rhodanese DYD2_k127_4537443_3 1163617.SCD_n02324 4.043e-117 383.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c DYD2_k127_4537443_0 221288.JH992901_gene802 7.046e-206 646.0 COG1062@1|root,COG1062@2|Bacteria,1G2S4@1117|Cyanobacteria,1JHQU@1189|Stigonemataceae 1117|Cyanobacteria C Zinc-binding dehydrogenase frmA - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_4537443_18 1123253.AUBD01000011_gene2078 9.776e-10 70.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RYFT@1236|Gammaproteobacteria,1X3IT@135614|Xanthomonadales 1236|Gammaproteobacteria EU peptidase - - - - - - - - - - - - PD40,Peptidase_S9 DYD2_k127_4537443_11 1207063.P24_08379 4.396e-60 218.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2JRJV@204441|Rhodospirillales 204441|Rhodospirillales G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - - - - - - - - - - Aldolase_II DYD2_k127_4537444_5 1095769.CAHF01000011_gene2396 6.697e-55 199.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,472YF@75682|Oxalobacteraceae 28216|Betaproteobacteria S Tetratricopeptide repeat-like domain - - - - - - - - - - - - TPR_21 DYD2_k127_4537444_3 1163617.SCD_n01806 3.946e-117 388.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 DYD2_k127_4537444_0 580332.Slit_1418 3.337e-193 616.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,44V5G@713636|Nitrosomonadales 28216|Betaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 DYD2_k127_4537444_6 640081.Dsui_3137 1.689e-38 145.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,2KWYA@206389|Rhodocyclales 206389|Rhodocyclales J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq DYD2_k127_4537444_2 1163617.SCD_n01801 3.177e-147 475.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria 28216|Betaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 DYD2_k127_4537444_1 1163617.SCD_n01800 2.382e-166 532.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria 28216|Betaproteobacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N DYD2_k127_4537444_4 1288494.EBAPG3_4020 9.596e-90 301.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,371T3@32003|Nitrosomonadales 28216|Betaproteobacteria O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 DYD2_k127_454273_2 1123504.JQKD01000019_gene5539 1.751e-188 608.0 COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,2VH0U@28216|Betaproteobacteria,4AAMR@80864|Comamonadaceae 28216|Betaproteobacteria J Translation elongation factor - - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 DYD2_k127_454273_8 34007.IT40_09370 4.063e-72 257.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria 1224|Proteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_3,cNMP_binding DYD2_k127_454273_11 1515746.HR45_00725 7.049e-06 49.0 COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,1RQJI@1236|Gammaproteobacteria,2Q8ZI@267890|Shewanellaceae 1236|Gammaproteobacteria J Translation elongation factor selB GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 DYD2_k127_454273_9 321955.AAGP01000031_gene1179 3.938e-70 249.0 COG3181@1|root,COG3181@2|Bacteria,2GJ89@201174|Actinobacteria 201174|Actinobacteria S protein conserved in bacteria - - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC DYD2_k127_454273_4 795666.MW7_1725 4.599e-163 528.0 COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNBG@28216|Betaproteobacteria,1K297@119060|Burkholderiaceae 28216|Betaproteobacteria P Pfam Sulfatase - - 3.1.6.6 ko:K01133 - - - - ko00000,ko01000 - - - DUF4976,Sulfatase DYD2_k127_454273_7 266264.Rmet_5278 1.946e-92 314.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria 28216|Betaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_454273_3 1380394.JADL01000001_gene2481 5.57e-173 554.0 COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE PrpD family protein - - - - - - - - - - - - MmgE_PrpD DYD2_k127_454273_10 1380354.JIAN01000007_gene155 2.432e-07 63.0 COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria 201174|Actinobacteria E Saccharopine dehydrogenase lys1 - 1.5.1.7 ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715 RC00217,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP DYD2_k127_454273_0 1207063.P24_13673 1.362e-207 656.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JQSB@204441|Rhodospirillales 204441|Rhodospirillales C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_binding_2 DYD2_k127_454273_1 1380394.JADL01000001_gene2482 6.983e-202 643.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE PrpD family protein - - - - - - - - - - - - MmgE_PrpD DYD2_k127_454273_5 1380394.JADL01000001_gene1955 7.788e-134 438.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2U0B2@28211|Alphaproteobacteria,2JZMD@204441|Rhodospirillales 204441|Rhodospirillales E Peptidase family M28 - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD2_k127_454273_6 1303518.CCALI_01700 3.561e-103 353.0 COG2079@1|root,COG2079@2|Bacteria 2|Bacteria S 2-methylcitrate dehydratase activity prpD GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD DYD2_k127_4557074_6 1205680.CAKO01000002_gene2508 4.128e-59 208.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TUWV@28211|Alphaproteobacteria,2JQWC@204441|Rhodospirillales 204441|Rhodospirillales E Pyridoxal-phosphate dependent enzyme - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_4557074_4 1366050.N234_21875 2.51e-81 282.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_4557074_0 266265.Bxe_A4452 2.458e-217 683.0 COG0644@1|root,COG0644@2|Bacteria,1QM8G@1224|Proteobacteria,2VJQ9@28216|Betaproteobacteria,1K4HE@119060|Burkholderiaceae 28216|Betaproteobacteria C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored DYD2_k127_4557074_1 1379698.RBG1_1C00001G0900 3.267e-194 639.0 COG1529@1|root,COG1529@2|Bacteria,2NNTR@2323|unclassified Bacteria 2|Bacteria C Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - 1.17.1.5,1.2.5.3 ko:K03520,ko:K20447,ko:K20448 ko00760,ko01120,map00760,map01120 - R01720,R11168 RC00589,RC02800 ko00000,ko00001,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_4557074_2 1205680.CAKO01000038_gene1894 6.254e-163 526.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria,2JS3D@204441|Rhodospirillales 204441|Rhodospirillales J Amidase - - - - - - - - - - - - Amidase DYD2_k127_4557074_5 1366050.N234_22760 7.043e-78 272.0 COG3181@1|root,COG3181@2|Bacteria,1PBQE@1224|Proteobacteria,2VPQG@28216|Betaproteobacteria 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_4557074_3 257310.BB4925 1.325e-92 316.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2VM0Y@28216|Betaproteobacteria,3T3NB@506|Alcaligenaceae 28216|Betaproteobacteria J Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase DYD2_k127_4605135_15 1121106.JQKB01000002_gene3396 2.768e-75 261.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,2JS11@204441|Rhodospirillales 204441|Rhodospirillales C FMN-dependent dehydrogenase - - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh DYD2_k127_4605135_8 1205680.CAKO01000030_gene4901 9.846e-113 371.0 COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales 204441|Rhodospirillales Q Taurine catabolism dioxygenase TauD, TfdA family - - - ko:K22303 - - - - ko00000,ko01000 - - - TauD DYD2_k127_4605135_12 1101190.ARWB01000001_gene3902 7.02e-86 298.0 COG0715@1|root,COG0715@2|Bacteria,1MWJF@1224|Proteobacteria,2TT19@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 DYD2_k127_4605135_7 426117.M446_0056 7.101e-114 375.0 COG1116@1|root,COG1116@2|Bacteria,1MUYG@1224|Proteobacteria,2TVQX@28211|Alphaproteobacteria,1JT6A@119045|Methylobacteriaceae 28211|Alphaproteobacteria P PFAM ABC transporter related - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD2_k127_4605135_10 1380394.JADL01000014_gene200 1.234e-99 334.0 COG0600@1|root,COG0600@2|Bacteria,1PC26@1224|Proteobacteria,2TV2Y@28211|Alphaproteobacteria,2JVC6@204441|Rhodospirillales 204441|Rhodospirillales P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 DYD2_k127_4605135_11 1131814.JAFO01000001_gene3618 3.712e-93 316.0 COG0600@1|root,COG0600@2|Bacteria,1PC26@1224|Proteobacteria,2TV2Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD2_k127_4605135_5 511.JT27_02375 5.048e-149 481.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2VJAW@28216|Betaproteobacteria,3T1E3@506|Alcaligenaceae 28216|Betaproteobacteria S PrpF protein - - - - - - - - - - - - PrpF DYD2_k127_4605135_14 351607.Acel_0891 7.379e-82 297.0 COG2128@1|root,COG2128@2|Bacteria,2HTUG@201174|Actinobacteria,4EUKU@85013|Frankiales 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - - DYD2_k127_4605135_13 1380394.JADL01000020_gene1824 1.89e-82 288.0 COG0477@1|root,COG2814@2|Bacteria,1QUTR@1224|Proteobacteria,2TW7A@28211|Alphaproteobacteria,2JZ6R@204441|Rhodospirillales 204441|Rhodospirillales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_4605135_4 1123237.Salmuc_01626 2.039e-150 503.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2U3FU@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_2,Cu-oxidase_3 DYD2_k127_4605135_24 391038.Bphy_1794 1.728e-20 99.0 COG2913@1|root,COG2913@2|Bacteria,1RBY9@1224|Proteobacteria,2VSW7@28216|Betaproteobacteria,1K4ZB@119060|Burkholderiaceae 28216|Betaproteobacteria J (Lipo)protein - - - - - - - - - - - - SmpA_OmlA DYD2_k127_4605135_25 864051.BurJ1DRAFT_0273 1.368e-16 86.0 COG2913@1|root,COG2913@2|Bacteria,1RBY9@1224|Proteobacteria,2VSW7@28216|Betaproteobacteria 28216|Betaproteobacteria J (Lipo)protein - - - - - - - - - - - - SmpA_OmlA DYD2_k127_4605135_27 1005048.CFU_3481 3.95e-15 83.0 COG2913@1|root,COG2913@2|Bacteria,1RBY9@1224|Proteobacteria,2VSW7@28216|Betaproteobacteria,474Q5@75682|Oxalobacteraceae 28216|Betaproteobacteria J SmpA / OmlA family - - - - - - - - - - - - SmpA_OmlA DYD2_k127_4605135_1 196490.AUEZ01000047_gene6728 4.52e-197 621.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2TR7I@28211|Alphaproteobacteria,3JRS7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EK Alanine-glyoxylate amino-transferase MA20_07365 - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR DYD2_k127_4605135_18 1205680.CAKO01000029_gene4983 1.92e-45 180.0 COG0667@1|root,COG0667@2|Bacteria,1R5BH@1224|Proteobacteria,2TS0A@28211|Alphaproteobacteria,2JVHZ@204441|Rhodospirillales 204441|Rhodospirillales C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD2_k127_4605135_23 323850.Shew_0376 1.628e-23 113.0 28PJS@1|root,2ZC9A@2|Bacteria,1N7QV@1224|Proteobacteria,1SD8M@1236|Gammaproteobacteria,2QC9D@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM Curlin associated repeat protein - - - - - - - - - - - - Curlin_rpt DYD2_k127_4605135_30 379731.PST_2126 9.075e-05 51.0 28PJS@1|root,2ZC9A@2|Bacteria,1R8QE@1224|Proteobacteria,1RZKZ@1236|Gammaproteobacteria,1Z1NE@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Curlin associated repeat - - - - - - - - - - - - Curlin_rpt DYD2_k127_4605135_19 1298593.TOL_3054 1.249e-44 172.0 COG2197@1|root,COG2197@2|Bacteria,1MXI3@1224|Proteobacteria,1RNEY@1236|Gammaproteobacteria,1XM33@135619|Oceanospirillales 135619|Oceanospirillales K LuxR family transcriptional regulator - - - ko:K04333,ko:K20918 ko02026,ko05111,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - GerE DYD2_k127_4605135_26 1231391.AMZF01000003_gene3135 7.782e-16 83.0 2C2E6@1|root,32QAT@2|Bacteria,1QT17@1224|Proteobacteria,2W44V@28216|Betaproteobacteria,3T821@506|Alcaligenaceae 28216|Betaproteobacteria S Curli assembly protein CsgE - - - ko:K04337 - - - - ko00000,ko02044 - - - CsgE DYD2_k127_4605135_22 1231391.AMZF01000003_gene3136 7.114e-35 138.0 2DEP1@1|root,32U3R@2|Bacteria,1N4PQ@1224|Proteobacteria,2W55A@28216|Betaproteobacteria 28216|Betaproteobacteria S Type VIII secretion system (T8SS), CsgF protein - - - ko:K04338 - - - - ko00000,ko02044 - - - CsgF DYD2_k127_4605135_9 1231391.AMZF01000003_gene3137 3.514e-101 338.0 COG1462@1|root,COG1462@2|Bacteria,1MVZM@1224|Proteobacteria,2VXWK@28216|Betaproteobacteria,3T6VH@506|Alcaligenaceae 28216|Betaproteobacteria M Curli production assembly/transport component CsgG - - - ko:K06214 - - - - ko00000,ko02044 - - - CsgG DYD2_k127_4605135_17 580332.Slit_2140 9.086e-57 203.0 COG1225@1|root,COG1225@2|Bacteria,1RH4P@1224|Proteobacteria,2VT1P@28216|Betaproteobacteria,44WFG@713636|Nitrosomonadales 28216|Betaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD2_k127_4605135_2 1157708.KB907462_gene884 7.278e-171 547.0 COG0277@1|root,COG0277@2|Bacteria,1N4UQ@1224|Proteobacteria,2W1U4@28216|Betaproteobacteria,4AHE1@80864|Comamonadaceae 28216|Betaproteobacteria C FAD binding domain - - - - - - - - - - - - FAD_binding_4 DYD2_k127_4605135_3 338969.Rfer_0826 2.401e-155 500.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VSBW@28216|Betaproteobacteria,4AGV6@80864|Comamonadaceae 28216|Betaproteobacteria M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS DYD2_k127_4605135_20 29581.BW37_01644 1.383e-43 163.0 COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2VRD4@28216|Betaproteobacteria,477DK@75682|Oxalobacteraceae 28216|Betaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase gloA3 - - - - - - - - - - - Glyoxalase DYD2_k127_4605135_6 375286.mma_0185 3.365e-115 381.0 2C7F6@1|root,2Z8AK@2|Bacteria,1PEE5@1224|Proteobacteria,2VKQ6@28216|Betaproteobacteria,476M3@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_4605135_16 1000565.METUNv1_02420 3.043e-72 254.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,2KW45@206389|Rhodocyclales 206389|Rhodocyclales M VacJ family lipoprotein vacJ - - ko:K04754 - - - - ko00000 - - - MlaA DYD2_k127_4605135_0 1380394.JADL01000011_gene3804 2.736e-203 641.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPSC@204441|Rhodospirillales 204441|Rhodospirillales C belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_4617935_3 261292.Nit79A3_3271 2.647e-87 296.0 28JXP@1|root,2Z9N4@2|Bacteria,1MXG4@1224|Proteobacteria,2WBED@28216|Betaproteobacteria,372YW@32003|Nitrosomonadales 28216|Betaproteobacteria S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - - - - - - - - - - Peptidase_C92 DYD2_k127_4617935_2 324602.Caur_0549 5.707e-116 386.0 COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function (DUF3179) - - - - - - - - - - - - DUF3179 DYD2_k127_4617935_5 543728.Vapar_6307 1.919e-62 225.0 COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2VU9I@28216|Betaproteobacteria,4AEMB@80864|Comamonadaceae 28216|Betaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX DYD2_k127_4617935_4 1504672.669783898 6.752e-78 276.0 COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,2VR01@28216|Betaproteobacteria,4AE2Y@80864|Comamonadaceae 28216|Betaproteobacteria S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 DYD2_k127_4617935_1 1504672.669783899 4.181e-125 406.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,4AB9Y@80864|Comamonadaceae 28216|Betaproteobacteria S Belongs to the UPF0276 family - - - ko:K09930 - - - - ko00000 - - - DUF692 DYD2_k127_4617935_6 1504672.669783900 1.056e-32 132.0 COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2VV7D@28216|Betaproteobacteria,4AF57@80864|Comamonadaceae 28216|Betaproteobacteria S Predicted integral membrane protein (DUF2282) - - - - - - - - - - - - DUF2282 DYD2_k127_4617935_7 323848.Nmul_A0234 1.035e-18 88.0 COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,373KV@32003|Nitrosomonadales 28216|Betaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S DYD2_k127_4617935_0 1266925.JHVX01000005_gene2009 1.975e-126 415.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,3724A@32003|Nitrosomonadales 28216|Betaproteobacteria H Belongs to the FPP GGPP synthase family ispA - 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt DYD2_k127_4622065_1 1000565.METUNv1_00684 1.286e-27 116.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,2KXC5@206389|Rhodocyclales 206389|Rhodocyclales K Cold shock protein domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD2_k127_4622065_0 640512.BC1003_2611 8.678e-71 245.0 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria,1JZZC@119060|Burkholderiaceae 28216|Betaproteobacteria G Phosphoglycolate phosphatase gph - 3.1.3.105 ko:K22292 ko00520,map00520 - R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 DYD2_k127_4683921_5 1286093.C266_18146 1.028e-98 329.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,1K2CE@119060|Burkholderiaceae 28216|Betaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA DYD2_k127_4683921_0 977880.RALTA_A2112 5.926e-223 694.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,1JZSI@119060|Burkholderiaceae 28216|Betaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_4683921_6 1485544.JQKP01000005_gene356 5.478e-79 268.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,44VEB@713636|Nitrosomonadales 28216|Betaproteobacteria E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI DYD2_k127_4683921_4 640081.Dsui_3194 9.978e-104 346.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,2KU8S@206389|Rhodocyclales 206389|Rhodocyclales J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 DYD2_k127_4683921_3 1123393.KB891316_gene1194 3.73e-110 388.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,1KRKB@119069|Hydrogenophilales 119069|Hydrogenophilales NU pilus assembly protein FimV - - - ko:K08086 - - - - ko00000 - - - - DYD2_k127_4683921_1 1452718.JBOY01000042_gene1870 1.444e-167 534.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD2_k127_4683921_2 1163617.SCD_n00875 1.162e-162 519.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria 28216|Betaproteobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD2_k127_4683921_7 265072.Mfla_1704 6.039e-19 86.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,2KM7B@206350|Nitrosomonadales 206350|Nitrosomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD2_k127_4690811_6 1123393.KB891317_gene2463 6.794e-48 174.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,1KRKH@119069|Hydrogenophilales 119069|Hydrogenophilales GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase DYD2_k127_4690811_1 1288494.EBAPG3_25970 6.638e-154 490.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,372JI@32003|Nitrosomonadales 28216|Betaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysM GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_4690811_0 1163617.SCD_n01045 5.14e-168 550.0 COG2911@1|root,COG2911@2|Bacteria,1MW9V@1224|Proteobacteria,2VI9X@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - DYD2_k127_4690811_7 1000565.METUNv1_02737 5.421e-13 76.0 2EI4D@1|root,33BVR@2|Bacteria,1NJXH@1224|Proteobacteria,2VY5M@28216|Betaproteobacteria,2KXH6@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD2_k127_4690811_5 305700.B447_01046 5.803e-49 181.0 COG3784@1|root,COG3784@2|Bacteria,1MYIH@1224|Proteobacteria,2VSM9@28216|Betaproteobacteria,2KWKK@206389|Rhodocyclales 206389|Rhodocyclales S protein conserved in bacteria - - - ko:K09978 - - - - ko00000 - - - DUF1318 DYD2_k127_4690811_2 323848.Nmul_A2217 2.081e-128 413.0 COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,372UD@32003|Nitrosomonadales 28216|Betaproteobacteria L Predicted 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 DYD2_k127_4690811_3 338969.Rfer_4185 6.188e-82 280.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase ubiE - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 DYD2_k127_4690811_4 257313.BP1725 2.305e-77 262.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,3T29H@506|Alcaligenaceae 28216|Betaproteobacteria J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr DYD2_k127_4699345_4 472175.EL18_02584 2.492e-86 293.0 COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2VF93@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD2_k127_4699345_5 472175.EL18_02582 4.89e-76 275.0 COG0747@1|root,COG0747@2|Bacteria 2|Bacteria E dipeptide transport - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 DYD2_k127_4699345_2 1120971.AUCA01000001_gene1697 3.35e-106 353.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,2793D@186823|Alicyclobacillaceae 91061|Bacilli EP Belongs to the ABC transporter superfamily - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY DYD2_k127_4699345_1 472175.EL18_02586 5.016e-116 383.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,43HCS@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Belongs to the ABC transporter superfamily MA20_14330 - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY DYD2_k127_4699345_0 1499967.BAYZ01000095_gene4241 2.097e-168 563.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 DYD2_k127_4699345_3 1499967.BAYZ01000095_gene4251 1.863e-88 315.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - - - - - - - - - - BatA,VWA_2 DYD2_k127_4791867_4 864073.HFRIS_001325 8.778e-100 339.0 COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,472VX@75682|Oxalobacteraceae 28216|Betaproteobacteria H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N DYD2_k127_4791867_3 1207063.P24_04989 2.516e-111 373.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,2JQ7C@204441|Rhodospirillales 204441|Rhodospirillales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD2_k127_4791867_0 1411123.JQNH01000001_gene3814 2.516e-182 577.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TV99@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the citrate synthase family prpC - 2.3.3.1,2.3.3.5 ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351,R00931 RC00004,RC00067,RC00406,RC02827 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD2_k127_4791867_2 1411123.JQNH01000001_gene3813 2.395e-114 377.0 COG0280@1|root,COG0280@2|Bacteria,1QTS5@1224|Proteobacteria,2TVFP@28211|Alphaproteobacteria 28211|Alphaproteobacteria C phosphate acetyltransferase - - 2.3.1.8 ko:K00625 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - PTA_PTB DYD2_k127_4791867_1 479434.Sthe_1507 4.386e-140 457.0 COG0477@1|root,COG2814@2|Bacteria,2G8DX@200795|Chloroflexi 200795|Chloroflexi EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1 DYD2_k127_4791867_6 292415.Tbd_1307 8.348e-31 124.0 2A022@1|root,30N4D@2|Bacteria,1PU9H@1224|Proteobacteria,2WARI@28216|Betaproteobacteria,1KRVX@119069|Hydrogenophilales 119069|Hydrogenophilales S Domain of unknown function (DUF1840) - - - - - - - - - - - - DUF1840 DYD2_k127_4791867_5 706587.Desti_2217 6.059e-61 216.0 COG3247@1|root,COG3247@2|Bacteria,1RFIH@1224|Proteobacteria,42XZY@68525|delta/epsilon subdivisions,2WSXS@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 DYD2_k127_4798693_2 477184.KYC_07515 5.347e-138 444.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,3T5BW@506|Alcaligenaceae 28216|Betaproteobacteria EG Belongs to the IlvD Edd family - - 4.2.1.82,4.2.1.9 ko:K01687,ko:K22186 ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R02429,R04441,R05070 RC00468,RC00543,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD2_k127_4798693_3 1088721.NSU_0979 5.646e-78 268.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2TSPC@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg DYD2_k127_4798693_7 1088721.NSU_0980 7.891e-25 109.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - ko:K21700 - - - - ko00000 - - - Cupin_2 DYD2_k127_4798693_8 1485544.JQKP01000001_gene1043 1.237e-05 55.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - His_kinase DYD2_k127_4798693_4 1088721.NSU_0982 3.09e-56 210.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U103@28211|Alphaproteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - His_kinase DYD2_k127_4798693_5 1121939.L861_01340 4.171e-36 143.0 2E1NG@1|root,32WZD@2|Bacteria,1N1TR@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_4798693_1 639283.Snov_0546 7.117e-150 486.0 COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,3F0KV@335928|Xanthobacteraceae 28211|Alphaproteobacteria S repeat protein - - - - - - - - - - - - LVIVD DYD2_k127_4798693_0 196367.JNFG01000031_gene8767 0.0 1150.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1K1NF@119060|Burkholderiaceae 28216|Betaproteobacteria C aconitate hydratase - - - - - - - - - - - - Aconitase,Aconitase_C DYD2_k127_4798693_6 1184267.A11Q_1834 7.505e-31 125.0 COG0583@1|root,COG0583@2|Bacteria,1NEWE@1224|Proteobacteria,4321H@68525|delta/epsilon subdivisions,2MUCR@213481|Bdellovibrionales,2WWNG@28221|Deltaproteobacteria 213481|Bdellovibrionales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_4823456_0 269799.Gmet_1676 1.805e-218 687.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales 28221|Deltaproteobacteria F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N DYD2_k127_4823456_10 1304883.KI912532_gene2564 1.133e-09 68.0 2CI9F@1|root,33H5J@2|Bacteria,1NH1E@1224|Proteobacteria,2VXVR@28216|Betaproteobacteria,2KXJZ@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD2_k127_4823456_8 1532557.JL37_10335 1.227e-26 119.0 COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria,3T7T0@506|Alcaligenaceae 28216|Betaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE DYD2_k127_4823456_4 1207063.P24_12502 1.92e-71 264.0 COG2271@1|root,COG2271@2|Bacteria,1R8Q1@1224|Proteobacteria,2U16E@28211|Alphaproteobacteria,2JRZF@204441|Rhodospirillales 204441|Rhodospirillales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_4823456_5 1118153.MOY_14757 8.942e-68 248.0 COG2223@1|root,COG2223@2|Bacteria,1QWEE@1224|Proteobacteria 1224|Proteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD2_k127_4823456_1 1197906.CAJQ02000044_gene1618 2.306e-167 554.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TUVG@28211|Alphaproteobacteria,3JTCJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_4823456_9 1121946.AUAX01000018_gene6959 5.14e-20 96.0 COG0662@1|root,COG0662@2|Bacteria,2IKT6@201174|Actinobacteria,4DEQ5@85008|Micromonosporales 201174|Actinobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_4823456_6 296591.Bpro_1765 3.73e-51 193.0 COG0583@1|root,COG0583@2|Bacteria,1P2I1@1224|Proteobacteria,2VTWR@28216|Betaproteobacteria,4AF4P@80864|Comamonadaceae 28216|Betaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_4823456_3 472175.EL18_02584 9.78e-91 309.0 COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2VF93@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD2_k127_4823456_7 1366050.N234_03265 7.013e-46 177.0 COG0583@1|root,COG0583@2|Bacteria,1R67G@1224|Proteobacteria,2VIWZ@28216|Betaproteobacteria,1K5KH@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_4823456_2 1120983.KB894571_gene2617 5.988e-133 439.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TVCH@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - AMP-binding,AMP-binding_C DYD2_k127_4905715_0 580332.Slit_2752 1.145e-214 673.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,44VGZ@713636|Nitrosomonadales 28216|Betaproteobacteria J PFAM RNA-binding protein AU-1 Ribonuclease E G cafA - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD2_k127_4905715_7 323848.Nmul_A0579 4.316e-19 90.0 COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,373IG@32003|Nitrosomonadales 28216|Betaproteobacteria S Belongs to the UPF0235 family - - - ko:K09131 - - - - ko00000 - - - DUF167 DYD2_k127_4905715_5 1288494.EBAPG3_2600 5.138e-51 188.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria,3730Z@32003|Nitrosomonadales 28216|Betaproteobacteria S YGGT family - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT DYD2_k127_4905715_3 1434929.X946_1516 5.902e-84 287.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,1JZPH@119060|Burkholderiaceae 28216|Betaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer DYD2_k127_4905715_4 62928.azo3467 6.279e-77 265.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,2KU9T@206389|Rhodocyclales 206389|Rhodocyclales S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N DYD2_k127_4905715_2 1000565.METUNv1_03472 1.856e-196 615.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,2KVBG@206389|Rhodocyclales 206389|Rhodocyclales NU twitching motility protein pilT - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD2_k127_4905715_1 1163617.SCD_n00074 4.789e-200 631.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria 28216|Betaproteobacteria NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD2_k127_4905715_6 1123401.JHYQ01000014_gene862 5.619e-37 149.0 COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,1S132@1236|Gammaproteobacteria,46339@72273|Thiotrichales 72273|Thiotrichales S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE DYD2_k127_4914317_15 1117943.SFHH103_02831 3.858e-72 263.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,4BACM@82115|Rhizobiaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_4914317_9 158500.BV97_02897 1.198e-95 325.0 COG3435@1|root,COG3435@2|Bacteria,1MVJP@1224|Proteobacteria,2TUUS@28211|Alphaproteobacteria,2K0EX@204457|Sphingomonadales 204457|Sphingomonadales Q Cupin domain - - 1.13.11.4 ko:K00450 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R02656 RC00764 ko00000,ko00001,ko01000 - - - Cupin_2 DYD2_k127_4914317_23 1254432.SCE1572_23905 1.365e-47 179.0 COG0346@1|root,COG0346@2|Bacteria,1RI3Q@1224|Proteobacteria,43DXJ@68525|delta/epsilon subdivisions,2WZ51@28221|Deltaproteobacteria,2Z1CE@29|Myxococcales 28221|Deltaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - - DYD2_k127_4914317_18 118168.MC7420_3515 2.533e-64 243.0 COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales 1117|Cyanobacteria S TIM-barrel fold metal-dependent hydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_4914317_33 237368.SCABRO_02034 9.244e-28 124.0 COG4642@1|root,COG4642@2|Bacteria 2|Bacteria S regulation of ryanodine-sensitive calcium-release channel activity - - - - - - - - - - - - MORN DYD2_k127_4914317_17 227086.JGI_V11_33711 4.458e-67 239.0 2BBKE@1|root,2S0Y6@2759|Eukaryota 2759|Eukaryota - - - - - - - - - - - - - - - DYD2_k127_4914317_20 1254432.SCE1572_31550 1.204e-52 201.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales 28221|Deltaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_4914317_11 596154.Alide2_3931 2.448e-85 297.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_4914317_8 1267534.KB906760_gene1581 3.961e-110 381.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - TPR_16,TPR_8 DYD2_k127_4914317_5 1210884.HG799463_gene9619 5.544e-114 380.0 COG3829@1|root,COG3829@2|Bacteria 2|Bacteria T transcription factor binding - - - ko:K15836 - - - - ko00000,ko03000 - - - GAF_2,HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat DYD2_k127_4914317_3 1242864.D187_004417 8.149e-130 421.0 COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,433UM@68525|delta/epsilon subdivisions,2XA3W@28221|Deltaproteobacteria,2YWAZ@29|Myxococcales 28221|Deltaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_4914317_10 1242864.D187_004418 4.445e-89 301.0 COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,438FQ@68525|delta/epsilon subdivisions,2X3QQ@28221|Deltaproteobacteria,2YWV7@29|Myxococcales 28221|Deltaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N DYD2_k127_4914317_0 331869.BAL199_02869 5.178e-239 758.0 COG1018@1|root,COG3576@1|root,COG1018@2|Bacteria,COG3576@2|Bacteria,1MV41@1224|Proteobacteria,2TQXP@28211|Alphaproteobacteria,4BQUF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Oxidoreductase NAD-binding domain - - 1.14.12.17 ko:K02613,ko:K05916,ko:K07006 ko00360,ko01120,ko05132,map00360,map01120,map05132 - R09838 RC02690 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,Globin,NAD_binding_1,Putative_PNPOx DYD2_k127_4914317_27 1000565.METUNv1_03706 2.229e-40 158.0 COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6F1@1224|Proteobacteria,2VMW2@28216|Betaproteobacteria,2KVZH@206389|Rhodocyclales 206389|Rhodocyclales P SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc DYD2_k127_4914317_14 744980.TRICHSKD4_4678 3.725e-73 252.0 29DWE@1|root,300UA@2|Bacteria,1RDK5@1224|Proteobacteria,2TY0U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cytochrome P460 - - - - - - - - - - - - Cytochrome_P460 DYD2_k127_4914317_19 614083.AWQR01000038_gene1437 2.702e-56 203.0 COG1633@1|root,COG1633@2|Bacteria,1R5K9@1224|Proteobacteria,2VQXI@28216|Betaproteobacteria,4AH47@80864|Comamonadaceae 28216|Betaproteobacteria S Domain of unknown function (DUF4439) - - - - - - - - - - - - Ferritin_2 DYD2_k127_4914317_32 59538.XP_005965322.1 5.722e-33 132.0 COG3474@1|root,KOG3453@2759|Eukaryota 2759|Eukaryota C electron transfer activity - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C DYD2_k127_4914317_12 1479237.JMLY01000001_gene2757 4.602e-79 270.0 COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,4671B@72275|Alteromonadaceae 1236|Gammaproteobacteria L Uracil-DNA glycosylase - - - - - - - - - - - - UDG DYD2_k127_4914317_22 388051.AUFE01000008_gene1709 3.109e-48 185.0 COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2VQNP@28216|Betaproteobacteria,1K7A5@119060|Burkholderiaceae 28216|Betaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily rpoE1 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD2_k127_4914317_34 1123354.AUDR01000014_gene1041 1.381e-14 83.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,1KRQ7@119069|Hydrogenophilales 119069|Hydrogenophilales K Uncharacterized ACR, COG1678 - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 DYD2_k127_4914317_6 1000565.METUNv1_03586 1.279e-111 364.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,2KW9G@206389|Rhodocyclales 206389|Rhodocyclales O Belongs to the GST superfamily - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_N DYD2_k127_4914317_1 1354722.JQLS01000001_gene4654 2.807e-141 458.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Metal-dependent hydrolase - - - - - - - - - - - - Cyclase DYD2_k127_4914317_28 331869.BAL199_05369 9.785e-39 146.0 COG2350@1|root,COG2350@2|Bacteria,1PZSM@1224|Proteobacteria,2UGH8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - YCII DYD2_k127_4914317_31 67315.JOBD01000002_gene2905 7.284e-34 134.0 COG0607@1|root,COG0607@2|Bacteria,2IN5N@201174|Actinobacteria 201174|Actinobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese DYD2_k127_4914317_30 1003200.AXXA_20868 2.865e-36 143.0 COG1846@1|root,COG1846@2|Bacteria,1QASF@1224|Proteobacteria,2VS2A@28216|Betaproteobacteria,3T7I0@506|Alcaligenaceae 28216|Betaproteobacteria K MarR family - - - - - - - - - - - - MarR_2 DYD2_k127_4914317_2 1142394.PSMK_27980 3.024e-135 447.0 COG1075@1|root,COG1075@2|Bacteria,2J2JB@203682|Planctomycetes 203682|Planctomycetes S Lecithin:cholesterol acyltransferase - - - - - - - - - - - - LCAT DYD2_k127_4914317_13 357808.RoseRS_3515 8.82e-76 261.0 COG1011@1|root,COG1011@2|Bacteria,2G7B3@200795|Chloroflexi,376JH@32061|Chloroflexia 32061|Chloroflexia S HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 DYD2_k127_4914317_35 153948.NAL212_0214 4.609e-09 59.0 297W1@1|root,2ZV2M@2|Bacteria,1QN4J@1224|Proteobacteria,2W2YU@28216|Betaproteobacteria,3747U@32003|Nitrosomonadales 28216|Betaproteobacteria S Domain of unknown function (DUF4396) - - - - - - - - - - - - DUF4396 DYD2_k127_4914317_24 744872.Spica_0212 7.694e-47 185.0 COG1653@1|root,COG1653@2|Bacteria,2J5W6@203691|Spirochaetes 203691|Spirochaetes G PFAM Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 DYD2_k127_4914317_21 742738.HMPREF9460_01004 9.858e-52 196.0 COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,269NE@186813|unclassified Clostridiales 186801|Clostridia G Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K05814,ko:K17316 ko02010,map02010 M00198,M00207,M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.24,3.A.1.1.3,3.A.1.1.30 - - BPD_transp_1 DYD2_k127_4914317_16 471853.Bcav_3574 7.588e-71 250.0 COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria 201174|Actinobacteria G ABC transporter (Permease) - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 DYD2_k127_4914317_7 357808.RoseRS_3083 1.335e-111 378.0 COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia 32061|Chloroflexia J Belongs to the amidase family - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD2_k127_4914317_4 1037409.BJ6T_87420 1.895e-124 411.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,3JW3J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E TOBE domain - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE_2 DYD2_k127_4914317_26 1297569.MESS2_1160035 4.344e-42 159.0 COG3791@1|root,COG3791@2|Bacteria,1RBIH@1224|Proteobacteria,2U5D0@28211|Alphaproteobacteria,43KSG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD2_k127_4914317_25 1205680.CAKO01000038_gene1591 6.457e-45 166.0 2DMD4@1|root,32NV5@2|Bacteria,1RI0E@1224|Proteobacteria,2UA1F@28211|Alphaproteobacteria,2JZT3@204441|Rhodospirillales 204441|Rhodospirillales S Conserved hypothetical protein (Lin0512_fam) - - - - - - - - - - - - Lin0512_fam DYD2_k127_4914317_29 1121106.JQKB01000016_gene5355 1.371e-38 155.0 2AJ2R@1|root,319M2@2|Bacteria,1RJXB@1224|Proteobacteria,2UA6I@28211|Alphaproteobacteria,2JY06@204441|Rhodospirillales 204441|Rhodospirillales S Conserved hypothetical protein (Lin0512_fam) - - - - - - - - - - - - Lin0512_fam DYD2_k127_50037_3 1163617.SCD_n02150 3.986e-22 97.0 COG2863@1|root,COG2863@2|Bacteria 2|Bacteria C cytochrome - - - - - - - - - - - - Cytochrom_C DYD2_k127_50037_1 1163617.SCD_n01692 3.711e-186 595.0 COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 DYD2_k127_50037_2 420324.KI912069_gene6356 1.168e-48 179.0 COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Electron transfer DM13 - - - - - - - - - - - - DM13 DYD2_k127_50037_0 1159870.KB907784_gene164 0.0 1074.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,3T1UC@506|Alcaligenaceae 28216|Betaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF DYD2_k127_5072104_13 388051.AUFE01000016_gene5765 2.438e-40 155.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VMVX@28216|Betaproteobacteria 28216|Betaproteobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD2_k127_5072104_2 1120983.KB894577_gene3578 9.341e-159 508.0 COG0673@1|root,COG0673@2|Bacteria,1PGFP@1224|Proteobacteria,2V8DN@28211|Alphaproteobacteria,1JQA3@119043|Rhodobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_5072104_4 1120983.KB894577_gene3579 3.571e-121 393.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2U6JP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase DYD2_k127_5072104_15 1120983.KB894577_gene3580 6.855e-36 145.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - 1.13.11.4,4.1.2.17 ko:K00450,ko:K01628 ko00051,ko00350,ko01100,ko01120,map00051,map00350,map01100,map01120 - R02262,R02656 RC00603,RC00604,RC00764 ko00000,ko00001,ko01000 - - - Cupin_2,Lipase_GDSL_2 DYD2_k127_5072104_16 1122134.KB893650_gene1428 6.096e-32 132.0 COG2128@1|root,COG2128@2|Bacteria,1PC51@1224|Proteobacteria,1RS2U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Carboxymuconolactone decarboxylase - - - - - - - - - - - - CMD DYD2_k127_5072104_17 1211579.PP4_21500 2.195e-23 112.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1RSE0@1236|Gammaproteobacteria 1236|Gammaproteobacteria E 2-dehydrogenase iolG - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_5072104_11 1147.D082_34610 2.251e-47 172.0 COG0537@1|root,COG0537@2|Bacteria,1G6R2@1117|Cyanobacteria,1H5PV@1142|Synechocystis 1117|Cyanobacteria FG HIT domain hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT DYD2_k127_5072104_14 323848.Nmul_A1984 4.43e-37 149.0 COG3218@1|root,COG3218@2|Bacteria,1N8NT@1224|Proteobacteria,2VTC7@28216|Betaproteobacteria,3734P@32003|Nitrosomonadales 28216|Betaproteobacteria S ABC-type transport auxiliary lipoprotein component - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux DYD2_k127_5072104_9 1288494.EBAPG3_22970 1.061e-66 240.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,372IQ@32003|Nitrosomonadales 28216|Betaproteobacteria Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD2_k127_5072104_8 1349767.GJA_251 1.075e-95 332.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria,472C1@75682|Oxalobacteraceae 28216|Betaproteobacteria Q AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD2_k127_5072104_3 1266925.JHVX01000014_gene1566 4.429e-135 441.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria,371SA@32003|Nitrosomonadales 28216|Betaproteobacteria Q Permease MlaE mlaE_2 - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD2_k127_5072104_12 1348657.M622_04340 5.365e-42 160.0 COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales 206389|Rhodocyclales S Phasin protein - - - - - - - - - - - - Phasin_2 DYD2_k127_5072104_18 1260251.SPISAL_06275 0.0009645 43.0 COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,1SZRM@1236|Gammaproteobacteria,1WWZE@135613|Chromatiales 135613|Chromatiales S Molybdopterin binding - - - - - - - - - - - - MoCF_biosynth DYD2_k127_5072104_10 1205753.A989_04778 1.277e-47 176.0 COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1T1K1@1236|Gammaproteobacteria,1X6ZX@135614|Xanthomonadales 135614|Xanthomonadales T CBS domain - - - - - - - - - - - - CBS DYD2_k127_5072104_1 1095769.CAHF01000010_gene1161 2.592e-160 541.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,473KS@75682|Oxalobacteraceae 28216|Betaproteobacteria T diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,MASE1,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,cNMP_binding DYD2_k127_5072104_6 375286.mma_0721 6.474e-112 370.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VMN7@28216|Betaproteobacteria,473IY@75682|Oxalobacteraceae 28216|Betaproteobacteria C PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain gyaR - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 - R00465,R00717,R01388,R01392,R01739 RC00031,RC00042,RC00084 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_5072104_5 1000565.METUNv1_04021 4.465e-118 393.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,2KURQ@206389|Rhodocyclales 28216|Betaproteobacteria C Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP DYD2_k127_5072104_0 1038859.AXAU01000008_gene2022 1.919e-164 528.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD2_k127_5072104_7 1120956.JHZK01000001_gene3373 1.097e-96 319.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,1JPPV@119043|Rhodobiaceae 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM DYD2_k127_5189282_6 288000.BBta_3275 2.639e-41 160.0 COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,2TRU9@28211|Alphaproteobacteria,3JVRE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - ko:K07046 ko00051,ko01120,map00051,map01120 - R10689 RC00537 ko00000,ko00001,ko01000 - - - Amidohydro_2 DYD2_k127_5189282_8 331869.BAL199_27201 3.091e-28 117.0 2E0H4@1|root,32W2Z@2|Bacteria,1N22D@1224|Proteobacteria,2UCZZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5189282_0 113395.AXAI01000015_gene504 3.622e-117 381.0 COG0412@1|root,COG0412@2|Bacteria,1R9JT@1224|Proteobacteria,2U4J1@28211|Alphaproteobacteria,3JWZE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH DYD2_k127_5189282_1 1168059.KB899087_gene1279 9.03e-113 378.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3F11J@335928|Xanthobacteraceae 28211|Alphaproteobacteria J Amidase - - - - - - - - - - - - Amidase DYD2_k127_5189282_10 237368.SCABRO_03032 4.237e-12 77.0 28U9J@1|root,2ZGF3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_5189282_7 228410.NE1204 1.106e-37 146.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2VKEE@28216|Betaproteobacteria,371XI@32003|Nitrosomonadales 28216|Betaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - DYD2_k127_5189282_11 713586.KB900536_gene1287 2.007e-07 55.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - DYD2_k127_5189282_2 887898.HMPREF0551_2331 9.933e-108 368.0 COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria,1K6NR@119060|Burkholderiaceae 28216|Betaproteobacteria T Domain of unknown function (DUF3391) - - - - - - - - - - - - DUF3391,HD,HD_5 DYD2_k127_5189282_3 713586.KB900536_gene2809 1.4e-65 232.0 COG2085@1|root,COG2085@2|Bacteria,1RCXR@1224|Proteobacteria,1S463@1236|Gammaproteobacteria 1236|Gammaproteobacteria S NADP oxidoreductase, coenzyme f420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD2_k127_5189282_4 1380394.JADL01000009_gene3308 2.633e-64 231.0 28JPA@1|root,2Z9FC@2|Bacteria,1PN1F@1224|Proteobacteria,2TSKX@28211|Alphaproteobacteria,2JUBG@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD2_k127_5189282_9 457421.CBFG_02499 3.389e-14 84.0 COG2159@1|root,COG2159@2|Bacteria,1VB68@1239|Firmicutes,24PD1@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Amidohydro_2 DYD2_k127_5189282_5 443598.AUFA01000040_gene6041 1.349e-55 217.0 COG3181@1|root,COG3181@2|Bacteria,1R89J@1224|Proteobacteria,2TW1T@28211|Alphaproteobacteria,3JW4M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_5234533_59 1288494.EBAPG3_13520 1.73e-25 110.0 2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,373GC@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF3106) - - - - - - - - - - - - DUF3106 DYD2_k127_5234533_56 153948.NAL212_1753 2.595e-30 125.0 COG1714@1|root,COG1714@2|Bacteria,1REEC@1224|Proteobacteria,2VRE0@28216|Betaproteobacteria,3738E@32003|Nitrosomonadales 28216|Betaproteobacteria S RDD family - - - - - - - - - - - - RDD DYD2_k127_5234533_20 1163617.SCD_n00813 2.346e-127 422.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria 28216|Betaproteobacteria S Permease, YjgP YjgQ family lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ DYD2_k127_5234533_23 580332.Slit_2409 3.09e-116 385.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,44V0Y@713636|Nitrosomonadales 28216|Betaproteobacteria S PFAM permease YjgP YjgQ family protein lptF - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ DYD2_k127_5234533_7 1288494.EBAPG3_20840 8.497e-209 659.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,372AV@32003|Nitrosomonadales 28216|Betaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N DYD2_k127_5234533_46 1163617.SCD_n00810 2.766e-51 186.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria 28216|Betaproteobacteria L dna polymerase III (Chi subunit) holC - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi DYD2_k127_5234533_0 556269.ACDQ01000013_gene631 0.0 1263.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,4724U@75682|Oxalobacteraceae 28216|Betaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 DYD2_k127_5234533_42 686340.Metal_2531 3.021e-58 208.0 28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,1XE83@135618|Methylococcales 135618|Methylococcales S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126 DYD2_k127_5234533_52 1123368.AUIS01000007_gene2769 3.095e-35 138.0 2F7T9@1|root,3407E@2|Bacteria,1NYX3@1224|Proteobacteria,1SQI5@1236|Gammaproteobacteria,2ND9Z@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - DYD2_k127_5234533_48 1121035.AUCH01000013_gene3129 7.686e-45 173.0 2B96M@1|root,322HU@2|Bacteria,1RIIU@1224|Proteobacteria,2VT7Z@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - FecR DYD2_k127_5234533_53 637389.Acaty_c2181 5.277e-34 134.0 2F8JF@1|root,340Y7@2|Bacteria,1NYW2@1224|Proteobacteria,1SQHY@1236|Gammaproteobacteria,2NCY0@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - DYD2_k127_5234533_60 1318628.MARLIPOL_02715 5.23e-24 113.0 2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,1SUQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5234533_8 396588.Tgr7_2204 8.397e-196 615.0 COG2516@1|root,COG2516@2|Bacteria,1MWZQ@1224|Proteobacteria,1RY3C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Radical SAM - - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM DYD2_k127_5234533_47 1458427.BAWN01000007_gene500 7.729e-50 190.0 COG3193@1|root,COG3193@2|Bacteria,1REF5@1224|Proteobacteria,2VT55@28216|Betaproteobacteria,4AEYR@80864|Comamonadaceae 28216|Betaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading DYD2_k127_5234533_21 396588.Tgr7_2205 6.966e-121 398.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_2,FAD_binding_3,FAD_oxidored,GIDA,Lycopene_cycl DYD2_k127_5234533_15 1163617.SCD_n00803 8.897e-148 475.0 COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,2VQNY@28216|Betaproteobacteria 28216|Betaproteobacteria H lipoate-protein ligase A lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB DYD2_k127_5234533_13 1158762.KB898048_gene669 1.888e-154 504.0 COG1856@1|root,COG1856@2|Bacteria,1R6PW@1224|Proteobacteria,1SKHD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SMART Elongator protein 3 MiaB NifB - - - ko:K09711 - - - - ko00000 - - - Radical_SAM DYD2_k127_5234533_43 637389.Acaty_c2187 3.747e-58 206.0 COG0509@1|root,COG0509@2|Bacteria,1N2U9@1224|Proteobacteria,1SC71@1236|Gammaproteobacteria,2NCVY@225057|Acidithiobacillales 225057|Acidithiobacillales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein - - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H DYD2_k127_5234533_10 519989.ECTPHS_10856 7.638e-173 544.0 COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,1SBBX@1236|Gammaproteobacteria,1X060@135613|Chromatiales 135613|Chromatiales C Cysteine-rich domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG DYD2_k127_5234533_28 1123368.AUIS01000007_gene2782 5.877e-101 335.0 COG1150@1|root,COG1150@2|Bacteria,1R874@1224|Proteobacteria,1SHQ0@1236|Gammaproteobacteria,2NBRI@225057|Acidithiobacillales 225057|Acidithiobacillales C 4Fe-4S dicluster domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03390 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4_17 DYD2_k127_5234533_41 1123368.AUIS01000007_gene2783 1.493e-58 216.0 arCOG05916@1|root,30GTU@2|Bacteria,1RDX8@1224|Proteobacteria,1SNV0@1236|Gammaproteobacteria,2NCJR@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - DYD2_k127_5234533_11 519989.ECTPHS_10841 9.412e-173 547.0 COG0446@1|root,COG1148@1|root,COG0446@2|Bacteria,COG1148@2|Bacteria,1R882@1224|Proteobacteria,1SAD3@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2 DYD2_k127_5234533_4 545264.KB898753_gene1745 6.332e-257 797.0 COG2048@1|root,COG2048@2|Bacteria,1R97P@1224|Proteobacteria,1SJXJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cysteine-rich domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG DYD2_k127_5234533_19 396595.TK90_0632 1.131e-131 423.0 COG1150@1|root,COG1150@2|Bacteria,1R7PH@1224|Proteobacteria,1SMDU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C 4Fe-4S dicluster domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03390 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4_8 DYD2_k127_5234533_55 1123393.KB891328_gene615 8.342e-32 124.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,1KTCC@119069|Hydrogenophilales 119069|Hydrogenophilales O Sulfurtransferase TusA - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA DYD2_k127_5234533_61 396588.Tgr7_2219 1.998e-23 102.0 2CARZ@1|root,2ZDWQ@2|Bacteria,1P7T2@1224|Proteobacteria,1STXE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5234533_12 580332.Slit_2416 4.038e-159 513.0 COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria 28216|Betaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,cNMP_binding DYD2_k127_5234533_16 1163617.SCD_n00796 3.256e-147 484.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria 28216|Betaproteobacteria S peptidase m48, ste24p yggG_1 - - - - - - - - - - - Peptidase_M48,TPR_19 DYD2_k127_5234533_39 1348657.M622_10405 1.766e-61 216.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,2KW2Z@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC DYD2_k127_5234533_49 1163617.SCD_n02411 5.73e-42 160.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria 28216|Betaproteobacteria S sulfur oxidation protein SoxY soxY - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY DYD2_k127_5234533_57 1268622.AVS7_01211 3.715e-29 119.0 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,4AEQV@80864|Comamonadaceae 28216|Betaproteobacteria S Sulphur oxidation protein SoxZ soxZ - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ DYD2_k127_5234533_34 93220.LV28_13545 3.491e-89 303.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2VJ8Q@28216|Betaproteobacteria,1K2BG@119060|Burkholderiaceae 28216|Betaproteobacteria C Thiosulfate-oxidizing multienzyme system protein SoxA soxA - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - DYD2_k127_5234533_45 93220.LV28_13540 3.232e-54 199.0 COG2010@1|root,COG2010@2|Bacteria,1P1GY@1224|Proteobacteria,2VP4W@28216|Betaproteobacteria,1K68I@119060|Burkholderiaceae 28216|Betaproteobacteria C Cytochrome c soxX - - ko:K17223 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Cytochrom_C DYD2_k127_5234533_3 1163617.SCD_n02408 3.386e-273 850.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria 28216|Betaproteobacteria F Belongs to the 5'-nucleotidase family soxB - 3.1.3.5,3.6.1.45 ko:K11751,ko:K17224 ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120 M00595 R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151 RC00017,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 - - - 5_nucleotid_C DYD2_k127_5234533_58 243233.MCA1510 8.838e-27 118.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1XFPQ@135618|Methylococcales 135618|Methylococcales U Belongs to the N-Me-Phe pilin family - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD2_k127_5234533_54 243233.MCA1510 5.926e-32 129.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1XFPQ@135618|Methylococcales 135618|Methylococcales U Belongs to the N-Me-Phe pilin family - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD2_k127_5234533_27 243233.MCA1512 2.702e-103 357.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,1S4C5@1236|Gammaproteobacteria,1XGYR@135618|Methylococcales 1236|Gammaproteobacteria M TPR repeat - - - - - - - - - - - - DUF29,Glyco_transf_9,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 DYD2_k127_5234533_50 756272.Plabr_0133 1.204e-38 151.0 COG0457@1|root,COG0500@1|root,COG0859@1|root,COG1215@1|root,COG0457@2|Bacteria,COG0500@2|Bacteria,COG0859@2|Bacteria,COG1215@2|Bacteria,2IYBQ@203682|Planctomycetes 203682|Planctomycetes M Tetratricopeptide repeat - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 DYD2_k127_5234533_32 1301098.PKB_1647 6.143e-90 315.0 COG1215@1|root,COG2520@1|root,COG1215@2|Bacteria,COG2520@2|Bacteria,1R5QX@1224|Proteobacteria 1224|Proteobacteria M Methyltransferase fkbm family - - - - - - - - - - - - Glycos_transf_2,Methyltransf_21 DYD2_k127_5234533_51 756272.Plabr_0131 1.685e-36 146.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - ko:K05303 - - - - ko00000,ko01000 - - - Methyltransf_24,TylF DYD2_k127_5234533_31 243233.MCA1512 9.465e-91 319.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,1S4C5@1236|Gammaproteobacteria,1XGYR@135618|Methylococcales 1236|Gammaproteobacteria M TPR repeat - - - - - - - - - - - - DUF29,Glyco_transf_9,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 DYD2_k127_5234533_26 243233.MCA1512 1.825e-106 375.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,1S4C5@1236|Gammaproteobacteria,1XGYR@135618|Methylococcales 1236|Gammaproteobacteria M TPR repeat - - - - - - - - - - - - DUF29,Glyco_transf_9,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 DYD2_k127_5234533_33 243233.MCA1511 2.23e-89 318.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,1S4C5@1236|Gammaproteobacteria,1XGYR@135618|Methylococcales 1236|Gammaproteobacteria M TPR repeat - - - - - - - - - - - - DUF29,Glyco_transf_9,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 DYD2_k127_5234533_25 243233.MCA1513 6.362e-108 353.0 COG1442@1|root,COG1442@2|Bacteria,1QH4S@1224|Proteobacteria 1224|Proteobacteria M glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 DYD2_k127_5234533_18 404380.Gbem_3741 3.777e-138 462.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,42PJA@68525|delta/epsilon subdivisions,2WMG0@28221|Deltaproteobacteria,43TUT@69541|Desulfuromonadales 28221|Deltaproteobacteria O repeat-containing protein - - - - - - - - - - - - Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8 DYD2_k127_5234533_38 748727.CLJU_c09650 7.636e-74 253.0 COG4627@1|root,COG4627@2|Bacteria,1UMZF@1239|Firmicutes,24UVP@186801|Clostridia 186801|Clostridia S Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 DYD2_k127_5234533_40 1265313.HRUBRA_02307 4.219e-61 218.0 COG0500@1|root,COG0500@2|Bacteria,1N2EQ@1224|Proteobacteria 1224|Proteobacteria Q methyltransferase - - - - - - - - - - - - - DYD2_k127_5234533_22 243233.MCA1516 2.944e-120 407.0 COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,1S4C5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M tpr domain protein - - - - - - - - - - - - DUF29,Glyco_transf_9,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 DYD2_k127_5234533_36 395495.Lcho_0484 2.538e-79 274.0 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 DYD2_k127_5234533_44 395495.Lcho_0484 7.42e-55 203.0 COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity - - - - - - - - - - - - Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25 DYD2_k127_5234533_62 395495.Lcho_0488 1.705e-21 103.0 2911D@1|root,2ZNNZ@2|Bacteria,1P8DV@1224|Proteobacteria,2W5MI@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5234533_6 580332.Slit_0537 2.528e-226 716.0 COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,44W5N@713636|Nitrosomonadales 28216|Betaproteobacteria T metal-dependent phosphohydrolase HD sub domain - - - - - - - - - - - - GAF,HD,HD_5 DYD2_k127_5234533_1 580332.Slit_0536 0.0 1100.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44VNC@713636|Nitrosomonadales 28216|Betaproteobacteria NU General secretory system II protein E domain protein - - - ko:K02454,ko:K02652,ko:K12276 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - GAF,T2SSE,T2SSE_N DYD2_k127_5234533_24 580332.Slit_0534 5.179e-113 371.0 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,44W4T@713636|Nitrosomonadales 28216|Betaproteobacteria S SMART beta-lactamase domain protein - - 3.1.4.17 ko:K01120 ko00230,map00230 - R00191,R01234 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 DYD2_k127_5234533_5 640081.Dsui_1452 2.527e-254 804.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,2KVW3@206389|Rhodocyclales 206389|Rhodocyclales T CHASE2 - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc DYD2_k127_5234533_37 1000565.METUNv1_02453 3.973e-78 274.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales 206389|Rhodocyclales T (FHA) domain - - - - - - - - - - - - FHA DYD2_k127_5234533_29 1000565.METUNv1_02452 5.723e-99 332.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,2KUQG@206389|Rhodocyclales 206389|Rhodocyclales T Serine/threonine phosphatases, family 2C, catalytic domain pppL - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 DYD2_k127_5234533_30 580332.Slit_0530 9.519e-95 318.0 COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria 28216|Betaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase DYD2_k127_5234533_17 1116369.KB890024_gene1623 1.584e-138 446.0 COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria,2U0GD@28211|Alphaproteobacteria,43P0N@69277|Phyllobacteriaceae 28211|Alphaproteobacteria J Formyl transferase, C-terminal domain - - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD2_k127_5234533_9 375286.mma_2347 1.859e-181 581.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,476TX@75682|Oxalobacteraceae 28216|Betaproteobacteria H CoA-transferase family III - - 2.8.3.16,2.8.3.22 ko:K07749,ko:K14471,ko:K14472 ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200 M00376 R00406,R03154 RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 DYD2_k127_5234533_2 296591.Bpro_2800 2.806e-321 989.0 COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VHRD@28216|Betaproteobacteria,4ABWV@80864|Comamonadaceae 28216|Betaproteobacteria EH Belongs to the TPP enzyme family oxc - 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 - R01908 RC00620 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_5234533_35 375286.mma_0398 1.651e-82 279.0 COG0664@1|root,COG0664@2|Bacteria,1R64V@1224|Proteobacteria,2VJXN@28216|Betaproteobacteria,472QZ@75682|Oxalobacteraceae 28216|Betaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding DYD2_k127_5234533_14 296591.Bpro_2797 1.446e-149 477.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAW5@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_5354491_6 349521.HCH_01486 4.653e-30 122.0 COG0457@1|root,COG0457@2|Bacteria,1QZ9R@1224|Proteobacteria,1S0PE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS DYD2_k127_5354491_5 93220.LV28_07800 1.528e-58 214.0 COG0346@1|root,COG0346@2|Bacteria,1RDVE@1224|Proteobacteria,2VREX@28216|Betaproteobacteria,1K4T8@119060|Burkholderiaceae 28216|Betaproteobacteria E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD2_k127_5354491_1 1207063.P24_09706 2.247e-108 370.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,2JQU6@204441|Rhodospirillales 204441|Rhodospirillales J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - - - - - - - - - - Amidase DYD2_k127_5354491_0 1382304.JNIL01000001_gene1394 2.059e-176 562.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes 1239|Firmicutes C carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 DYD2_k127_5354491_4 639283.Snov_0102 1.528e-63 230.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3EYRF@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_5354491_2 543728.Vapar_0801 4.683e-76 269.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJCY@28216|Betaproteobacteria,4ABM4@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_5354491_3 1121861.KB899915_gene1903 3.478e-75 263.0 COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2TVF5@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 DYD2_k127_5354491_7 126957.SMAR010443-PA 4.761e-23 107.0 COG0153@1|root,KOG0631@2759|Eukaryota,38ESX@33154|Opisthokonta,3BENI@33208|Metazoa,3D0CA@33213|Bilateria,41VGQ@6656|Arthropoda 33208|Metazoa G galactokinase activity. It is involved in the biological process described with GALK2 GO:0003674,GO:0003824,GO:0004335,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0031982,GO:0043226,GO:0043227,GO:0043230,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044421,GO:0044424,GO:0044464,GO:0046835,GO:0070062,GO:0071704,GO:1903561 2.7.1.157 ko:K18674 - - - - ko00000,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg DYD2_k127_5397956_2 653733.Selin_1396 4.508e-46 184.0 COG1960@1|root,COG1960@2|Bacteria 2|Bacteria I acyl-CoA dehydrogenase activity acdA - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_5397956_0 765912.Thimo_1862 1.049e-95 318.0 COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,1S0RN@1236|Gammaproteobacteria,1X0GG@135613|Chromatiales 135613|Chromatiales L PFAM Uracil-DNA glycosylase superfamily - - - ko:K10800 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - - DYD2_k127_5397956_1 1121413.JMKT01000011_gene2273 3.147e-58 209.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42PVD@68525|delta/epsilon subdivisions,2WM2C@28221|Deltaproteobacteria,2MG9A@213115|Desulfovibrionales 28221|Deltaproteobacteria S AI-2E family transporter - - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport DYD2_k127_540759_10 1163617.SCD_n02327 1.606e-47 174.0 COG0778@1|root,COG0778@2|Bacteria,1RA6E@1224|Proteobacteria,2VSIM@28216|Betaproteobacteria 28216|Betaproteobacteria C Pfam Nitroreductase - - - - - - - - - - - - Nitroreductase DYD2_k127_540759_0 1254432.SCE1572_33050 6.859e-188 606.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WKYA@28221|Deltaproteobacteria,2YU1C@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefB - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N DYD2_k127_540759_3 1266925.JHVX01000004_gene1257 9.537e-120 389.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,371WB@32003|Nitrosomonadales 28216|Betaproteobacteria O Glutathione S-transferase, N-terminal domain gstI - 2.5.1.18 ko:K00799,ko:K11209 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N,GST_N_2 DYD2_k127_540759_5 296591.Bpro_0282 4.866e-109 360.0 COG0583@1|root,COG0583@2|Bacteria,1N3XX@1224|Proteobacteria 1224|Proteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_540759_2 296591.Bpro_0285 5.679e-123 399.0 COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2VTMG@28216|Betaproteobacteria 28216|Betaproteobacteria ET ABC transporter substrate-binding protein - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD2_k127_540759_12 375286.mma_1899 9.374e-10 59.0 COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6F1@1224|Proteobacteria,2VMW2@28216|Betaproteobacteria,4723X@75682|Oxalobacteraceae 28216|Betaproteobacteria P SNARE associated Golgi protein dedA_2 - - - - - - - - - - - Rhodanese,SNARE_assoc DYD2_k127_540759_9 1123368.AUIS01000015_gene2649 2.861e-70 248.0 COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria,2NCA8@225057|Acidithiobacillales 225057|Acidithiobacillales P SNARE associated Golgi protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc DYD2_k127_540759_7 114615.BRADO5603 1.63e-90 314.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2TRJT@28211|Alphaproteobacteria,3JW10@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase MA20_02555 - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB DYD2_k127_540759_1 1123368.AUIS01000015_gene2648 2.155e-153 497.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,1RMTI@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-Transferase yqjG - 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 DYD2_k127_540759_11 998674.ATTE01000001_gene901 3.066e-43 162.0 COG2259@1|root,COG2259@2|Bacteria,1N06A@1224|Proteobacteria,1S92U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - ko:K15977 - - - - ko00000 - - - DoxX DYD2_k127_540759_8 1242864.D187_006621 1.628e-88 301.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,43AK0@68525|delta/epsilon subdivisions,2X60A@28221|Deltaproteobacteria,2Z0EU@29|Myxococcales 28221|Deltaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_540759_6 1392838.AWNM01000078_gene1126 8.93e-105 344.0 COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,3T3AA@506|Alcaligenaceae 28216|Betaproteobacteria S Belongs to the pirin family yhhW_2 - - ko:K06911 - - - - ko00000 - - - Pirin DYD2_k127_540759_4 32057.KB217483_gene9483 1.093e-109 365.0 COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria,1HQRD@1161|Nostocales 1117|Cyanobacteria O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD2_k127_5411510_2 742159.HMPREF0004_0584 0.0004809 47.0 2BZKD@1|root,31R02@2|Bacteria,1PVGB@1224|Proteobacteria,2WBA9@28216|Betaproteobacteria,3T85A@506|Alcaligenaceae 28216|Betaproteobacteria S Domain of unknown function (DUF4148) - - - - - - - - - - - - DUF4148 DYD2_k127_5411510_0 1485544.JQKP01000002_gene1412 7.492e-73 258.0 2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,44VSN@713636|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 DYD2_k127_5411510_1 388401.RB2150_08879 7.672e-52 185.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,3ZGNM@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria G TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM DYD2_k127_542874_1 887062.HGR_15444 2.845e-53 193.0 2CYEB@1|root,32T42@2|Bacteria,1MVVN@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_542874_2 1382304.JNIL01000001_gene3193 1.309e-43 169.0 COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,278UR@186823|Alicyclobacillaceae 91061|Bacilli IQ PFAM short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 DYD2_k127_542874_4 1283287.KB822577_gene3388 7.439e-34 137.0 COG2128@1|root,COG2128@2|Bacteria,2IBNX@201174|Actinobacteria 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD DYD2_k127_542874_3 330214.NIDE3368 4.01e-38 149.0 COG1259@1|root,COG1259@2|Bacteria 2|Bacteria K PFAM Uncharacterised ACR, COG1259 yqdE - - ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR DYD2_k127_542874_0 443598.AUFA01000040_gene6041 5.4e-55 199.0 COG3181@1|root,COG3181@2|Bacteria,1R89J@1224|Proteobacteria,2TW1T@28211|Alphaproteobacteria,3JW4M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_5458494_0 745411.B3C1_05427 5.847e-225 704.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1J4QP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind DYD2_k127_5458494_6 1120977.JHUX01000007_gene193 0.0006466 48.0 2ADX9@1|root,313PE@2|Bacteria,1RGY0@1224|Proteobacteria,1S83N@1236|Gammaproteobacteria,3NNCQ@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF2846) - - - - - - - - - - - - DUF2846 DYD2_k127_5458494_4 1234364.AMSF01000040_gene63 1.1e-11 71.0 2ADX9@1|root,313PE@2|Bacteria,1RGY0@1224|Proteobacteria,1S83N@1236|Gammaproteobacteria,1X89H@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF2846) - - - - - - - - - - - - DUF2846 DYD2_k127_5458494_3 243233.MCA0322 9.366e-32 126.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1XFM3@135618|Methylococcales 135618|Methylococcales J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 DYD2_k127_5458494_1 543913.D521_1842 2.111e-214 677.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VH8Z@28216|Betaproteobacteria,1KR7B@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD2_k127_5458494_2 1123072.AUDH01000001_gene2822 2.829e-126 409.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,2JRBE@204441|Rhodospirillales 204441|Rhodospirillales Q COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM DYD2_k127_5474273_25 172088.AUGA01000001_gene6752 2.297e-30 124.0 COG2084@1|root,COG2084@2|Bacteria,1R7WF@1224|Proteobacteria,2U3AW@28211|Alphaproteobacteria,3JS3Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 DYD2_k127_5474273_12 395019.Bmul_0209 1.255e-76 264.0 COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,2VN8Q@28216|Betaproteobacteria,1K0IY@119060|Burkholderiaceae 28216|Betaproteobacteria S Mut7-C RNAse domain - - - ko:K09122 - - - - ko00000 - - - Mut7-C,Ub-Mut7C DYD2_k127_5474273_2 1472716.KBK24_0113805 1.385e-291 908.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,1K1SY@119060|Burkholderiaceae 28216|Betaproteobacteria S abc transporter yjjK - 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn DYD2_k127_5474273_6 261292.Nit79A3_3045 7.958e-150 490.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,37202@32003|Nitrosomonadales 28216|Betaproteobacteria F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 DYD2_k127_5474273_13 29540.C481_20726 3.749e-72 257.0 arCOG10131@1|root,arCOG10131@2157|Archaea,2XWNY@28890|Euryarchaeota,23V3W@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - DYD2_k127_5474273_15 1117379.BABA_13707 2.78e-70 250.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis tlpA - - - - - - - - - - - Redoxin,Thioredoxin_8 DYD2_k127_5474273_8 502025.Hoch_3258 1.098e-96 333.0 COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,4385Z@68525|delta/epsilon subdivisions,2X3FT@28221|Deltaproteobacteria,2YVWY@29|Myxococcales 28221|Deltaproteobacteria GK ROK family - - 2.7.1.63 ko:K00886 ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R02187,R02189 RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK DYD2_k127_5474273_0 1089550.ATTH01000002_gene36 0.0 1038.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1FJTT@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran DYD2_k127_5474273_19 644282.Deba_2182 1.718e-52 201.0 COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42NTH@68525|delta/epsilon subdivisions,2WJ8N@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD2_k127_5474273_28 861299.J421_6143 1.563e-22 104.0 COG4032@1|root,COG4032@2|Bacteria 2|Bacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_N DYD2_k127_5474273_24 861299.J421_6144 1.013e-30 135.0 COG0028@1|root,COG0028@2|Bacteria 2|Bacteria EH Belongs to the TPP enzyme family - - - - - - - - - - - - TPP_enzyme_C DYD2_k127_5474273_5 76114.ebA3511 1.534e-180 587.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2VKEE@28216|Betaproteobacteria,2KXXQ@206389|Rhodocyclales 206389|Rhodocyclales S COG0457 FOG TPR repeat - - - - - - - - - - - - - DYD2_k127_5474273_17 1205680.CAKO01000010_gene3808 1.258e-62 225.0 COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,2TU8G@28211|Alphaproteobacteria,2JTBJ@204441|Rhodospirillales 204441|Rhodospirillales O Pyroglutamyl peptidase - - 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 DYD2_k127_5474273_33 1380390.JIAT01000010_gene4400 5.169e-08 63.0 COG2128@1|root,COG2128@2|Bacteria,2IFSC@201174|Actinobacteria 201174|Actinobacteria S PFAM Carboxymuconolactone decarboxylase - - - - - - - - - - - - CMD DYD2_k127_5474273_32 710687.KI912270_gene2074 2.209e-08 60.0 COG2128@1|root,COG2128@2|Bacteria,2IFSC@201174|Actinobacteria,2393W@1762|Mycobacteriaceae 201174|Actinobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD2_k127_5474273_34 397278.JOJN01000002_gene601 2.568e-05 49.0 COG2128@1|root,COG2128@2|Bacteria,2HZX3@201174|Actinobacteria,4DUDY@85009|Propionibacteriales 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - - DYD2_k127_5474273_1 1288494.EBAPG3_20660 0.0 1018.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,371RW@32003|Nitrosomonadales 28216|Betaproteobacteria P TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - 3.6.3.9 ko:K01539 ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978 - - - ko00000,ko00001,ko01000,ko04147 3.A.3.1 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 DYD2_k127_5474273_3 1123392.AQWL01000009_gene1141 2.785e-285 885.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,1KRCR@119069|Hydrogenophilales 119069|Hydrogenophilales J tRNA synthetases class I (E and Q), anti-codon binding domain - - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C DYD2_k127_5474273_20 883126.HMPREF9710_02652 4.36e-48 182.0 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,4747S@75682|Oxalobacteraceae 28216|Betaproteobacteria K Cyclic nucleotide-monophosphate binding domain dnrD - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding DYD2_k127_5474273_31 589865.DaAHT2_0247 1.493e-12 70.0 28XS9@1|root,2ZJNQ@2|Bacteria 2|Bacteria P Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrome_C7 DYD2_k127_5474273_18 1485545.JQLW01000005_gene922 4.595e-54 199.0 293CN@1|root,2Z9VJ@2|Bacteria,1MXNG@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_5474273_26 1283300.ATXB01000001_gene487 1.427e-25 121.0 COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,1SBJR@1236|Gammaproteobacteria,1XGZN@135618|Methylococcales 135618|Methylococcales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C DYD2_k127_5474273_30 553385.JEMF01000021_gene3070 4.176e-19 100.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales 135619|Oceanospirillales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD2_k127_5474273_29 702113.PP1Y_AT23279 1.506e-21 107.0 2E92Z@1|root,333BY@2|Bacteria,1N8J4@1224|Proteobacteria,2UI81@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5474273_21 159087.Daro_3859 5.534e-46 180.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,2KWMI@206389|Rhodocyclales 206389|Rhodocyclales C cytochrome c5 - - - - - - - - - - - - Cytochrome_CBB3 DYD2_k127_5474273_9 404589.Anae109_3085 6.4e-91 315.0 COG5557@1|root,COG5557@2|Bacteria,1R7R0@1224|Proteobacteria,42P0Z@68525|delta/epsilon subdivisions,2X7KR@28221|Deltaproteobacteria 28221|Deltaproteobacteria C PFAM Polysulphide reductase, NrfD - - - - - - - - - - - - NrfD DYD2_k127_5474273_14 404589.Anae109_3086 9.107e-71 253.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales 28221|Deltaproteobacteria C 4Fe-4S binding domain cbcT - - - - - - - - - - - Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7 DYD2_k127_5474273_23 28229.ND2E_2955 3.751e-35 147.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae 1236|Gammaproteobacteria C Cytochrome c cc4 - - - - - - - - - - - Cytochrom_C DYD2_k127_5474273_27 1379698.RBG1_1C00001G0295 1.554e-23 112.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - ko:K04013,ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_C552,Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1 DYD2_k127_5474273_11 748247.AZKH_1286 1.076e-84 292.0 COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,2VM47@28216|Betaproteobacteria,2KUB7@206389|Rhodocyclales 206389|Rhodocyclales C Cytochrome c554 and c-prime - - - - - - - - - - - - Paired_CXXCH_1 DYD2_k127_5474273_7 748247.AZKH_1287 5.357e-136 457.0 COG0653@1|root,COG0653@2|Bacteria,1QZ1G@1224|Proteobacteria,2VQGH@28216|Betaproteobacteria,2KWYF@206389|Rhodocyclales 1224|Proteobacteria U Putative outer membrane beta-barrel porin, MtrB/PioB - - - - - - - - - - - - MtrB_PioB DYD2_k127_5474273_10 1288494.EBAPG3_12740 2.46e-87 304.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,3722S@32003|Nitrosomonadales 28216|Betaproteobacteria O Tetratricopeptide repeat cycH - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_2 DYD2_k127_5474273_22 748247.AZKH_0317 2.045e-44 166.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,2KX2W@206389|Rhodocyclales 206389|Rhodocyclales P subunit of a heme lyase - - - ko:K02200 - - - - ko00000 - - - CcmH DYD2_k127_5474273_16 228410.NE0769 2.113e-63 222.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,372UU@32003|Nitrosomonadales 28216|Betaproteobacteria CO oxidoreductase DsbE dsbE - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin DYD2_k127_5474273_4 266265.Bxe_C0374 7.912e-240 750.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,1K1P2@119060|Burkholderiaceae 28216|Betaproteobacteria O Cytochrome c-type biogenesis protein CcmF ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD2_k127_5507577_1 1266925.JHVX01000006_gene2084 7.828e-233 728.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,371SD@32003|Nitrosomonadales 28216|Betaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD2_k127_5507577_15 1095769.CAHF01000010_gene1092 1.069e-15 89.0 COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria 28216|Betaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 DYD2_k127_5507577_11 1123023.JIAI01000002_gene4972 1.436e-64 231.0 COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD2_k127_5507577_7 264198.Reut_A1475 8.793e-106 359.0 COG0715@1|root,COG0715@2|Bacteria,1RJQU@1224|Proteobacteria,2VVYG@28216|Betaproteobacteria,1KB3C@119060|Burkholderiaceae 28216|Betaproteobacteria P Protein of unknown function (DUF3500) - - - - - - - - - - - - DUF3500 DYD2_k127_5507577_8 864702.OsccyDRAFT_3461 1.738e-90 325.0 COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales 1117|Cyanobacteria M Tetratricopeptide repeat - - - - - - - - - - - - DUF4915,Glyco_transf_9,Glycos_transf_1,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 DYD2_k127_5507577_6 909943.HIMB100_00004110 6.214e-142 457.0 COG3181@1|root,COG3181@2|Bacteria,1R49H@1224|Proteobacteria,2U1IK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_5507577_13 1366046.HIMB11_02127 7.902e-37 147.0 2DKXA@1|root,30R3Q@2|Bacteria,1RGIH@1224|Proteobacteria,2U71W@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD2_k127_5507577_2 666509.RCA23_c28360 6.697e-227 711.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_5507577_10 1380394.JADL01000003_gene4940 8.597e-83 284.0 COG4221@1|root,COG4221@2|Bacteria,1QW75@1224|Proteobacteria,2TWQR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S KR domain MA20_16520 - - - - - - - - - - - adh_short_C2 DYD2_k127_5507577_4 1424334.W822_02615 3.438e-157 505.0 COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2W9AM@28216|Betaproteobacteria,3T71C@506|Alcaligenaceae 28216|Betaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N DYD2_k127_5507577_9 762376.AXYL_03703 2.008e-89 308.0 COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria 1224|Proteobacteria M Capsule synthesis protein - - - ko:K07282 - - - - ko00000 - - - PGA_cap DYD2_k127_5507577_12 398527.Bphyt_2059 6.105e-41 155.0 COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,1K8M5@119060|Burkholderiaceae 28216|Betaproteobacteria T universal stress protein - - - - - - - - - - - - Usp DYD2_k127_5507577_3 204773.HEAR0343 1.638e-189 598.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,472FC@75682|Oxalobacteraceae 28216|Betaproteobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA DYD2_k127_5507577_5 153948.NAL212_1322 1.973e-155 494.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,371TW@32003|Nitrosomonadales 28216|Betaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 ko:K01902,ko:K08692 ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00346,M00374,M00620 R00405,R01256,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA DYD2_k127_5507577_0 1000565.METUNv1_01355 7.464e-267 831.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,2KVUQ@206389|Rhodocyclales 206389|Rhodocyclales C 24 kD subunit - - 1.17.1.9 ko:K00122 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB DYD2_k127_5507577_14 243233.MCA2576 1.48e-33 131.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1XEFY@135618|Methylococcales 1236|Gammaproteobacteria C Formate dehydrogenase, alpha subunit - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_8,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD2_k127_5655069_5 557598.LHK_03067 2.564e-40 150.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,2KPDZ@206351|Neisseriales 206351|Neisseriales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey DYD2_k127_5655069_0 580332.Slit_0134 7.508e-236 739.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,44VJ6@713636|Nitrosomonadales 28216|Betaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD2_k127_5655069_6 1485544.JQKP01000002_gene1498 1.848e-33 131.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,44VZT@713636|Nitrosomonadales 28216|Betaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln DYD2_k127_5655069_2 1485544.JQKP01000002_gene1499 4.487e-193 605.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,44VNI@713636|Nitrosomonadales 28216|Betaproteobacteria D TIGRFAM cell shape determining protein, MreB Mrl family mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD2_k127_5655069_3 1288494.EBAPG3_11700 4.567e-84 287.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,3729R@32003|Nitrosomonadales 28216|Betaproteobacteria M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC DYD2_k127_5655069_4 580332.Slit_0138 5.939e-46 171.0 COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,44VW1@713636|Nitrosomonadales 28216|Betaproteobacteria M rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD DYD2_k127_5655069_1 522306.CAP2UW1_0695 5.784e-208 657.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,1KPQQ@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M Penicillin-binding protein 2 mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase DYD2_k127_5677805_20 1245471.PCA10_43800 9.913e-63 219.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,1S03J@1236|Gammaproteobacteria,1YHY2@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 DYD2_k127_5677805_1 243160.BMA1358 2.388e-182 578.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,1K17R@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM L-carnitine dehydratase bile acid-inducible protein F frc_13 - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 DYD2_k127_5677805_13 1114964.L485_17130 3.16e-86 297.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria 28211|Alphaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - - DYD2_k127_5677805_25 1114964.L485_17125 3.623e-14 74.0 2BZD4@1|root,332J5@2|Bacteria,1RC8E@1224|Proteobacteria,2VGHM@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5677805_26 882083.SacmaDRAFT_4006 1.252e-11 71.0 2BZD4@1|root,33Y08@2|Bacteria,2GY7R@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD2_k127_5677805_7 1207063.P24_17837 1.194e-139 463.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2JR2A@204441|Rhodospirillales 204441|Rhodospirillales J Amidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase DYD2_k127_5677805_0 1366050.N234_13000 9.815e-241 756.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VIEX@28216|Betaproteobacteria,1K005@119060|Burkholderiaceae 28216|Betaproteobacteria EH Belongs to the TPP enzyme family ilvG - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_5677805_15 1380394.JADL01000002_gene1282 2.504e-85 293.0 COG2084@1|root,COG2084@2|Bacteria,1MWR4@1224|Proteobacteria,2U157@28211|Alphaproteobacteria,2JS1V@204441|Rhodospirillales 204441|Rhodospirillales I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 DYD2_k127_5677805_27 1167006.UWK_01469 1.625e-07 56.0 2EQK7@1|root,33I68@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_5677805_6 1202768.JROF01000032_gene1975 5.884e-142 464.0 COG2031@1|root,arCOG04315@2157|Archaea,2XUQ8@28890|Euryarchaeota,23T8F@183963|Halobacteria 183963|Halobacteria I COG2031 Short chain fatty acids transporter atoE - - ko:K02106 ko02020,map02020 - - - ko00000,ko00001 2.A.73.1 - - SCFA_trans DYD2_k127_5677805_21 1346791.M529_05605 1.088e-58 210.0 COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,2TW75@28211|Alphaproteobacteria,2KECA@204457|Sphingomonadales 204457|Sphingomonadales K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI DYD2_k127_5677805_5 1144325.PMI22_00658 3.067e-143 464.0 COG4948@1|root,COG4948@2|Bacteria,1MVFW@1224|Proteobacteria,1RYMG@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the mandelate racemase muconate lactonizing enzyme family - - 4.2.1.81 ko:K22209 - - - - ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N DYD2_k127_5677805_11 1298867.AUES01000007_gene4943 3.161e-89 310.0 COG3181@1|root,COG3181@2|Bacteria,1R9BJ@1224|Proteobacteria,2U4Z4@28211|Alphaproteobacteria,3JVRQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_5677805_14 1380394.JADL01000008_gene3523 1.763e-85 287.0 COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2TSX7@28211|Alphaproteobacteria,2JRUR@204441|Rhodospirillales 204441|Rhodospirillales G Class II Aldolase and Adducin N-terminal domain - - 4.1.1.104 ko:K22130 - - - - ko00000,ko01000 - - - Aldolase_II DYD2_k127_5677805_4 1380394.JADL01000008_gene3522 5.124e-162 520.0 COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,2TS85@28211|Alphaproteobacteria,2JQNX@204441|Rhodospirillales 204441|Rhodospirillales S Putative sugar-binding N-terminal domain - - 2.7.1.217 ko:K21948 - - R11706,R11707 - ko00000,ko01000 - - - DUF1357_C,DUF1537 DYD2_k127_5677805_16 232721.Ajs_1121 7.232e-85 291.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4AB79@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_5677805_12 1007105.PT7_0650 5.601e-89 307.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T21B@506|Alcaligenaceae 1224|Proteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_5677805_22 1038860.AXAP01000004_gene5204 2.015e-54 200.0 COG4126@1|root,COG4126@2|Bacteria,1MWVG@1224|Proteobacteria,2U0MW@28211|Alphaproteobacteria,3JS11@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Asp Glu hydantoin racemase MA20_16560 - - - - - - - - - - - - DYD2_k127_5677805_10 1038860.AXAP01000089_gene3713 8.09e-103 345.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3JWBY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD2_k127_5677805_9 631454.N177_0836 1.182e-124 413.0 COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_5677805_17 1268622.AVS7_03447 4.003e-84 291.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM conserved - - - - - - - - - - - - TctC DYD2_k127_5677805_8 1231391.AMZF01000037_gene583 8.555e-127 416.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VI5X@28216|Betaproteobacteria,3T6F3@506|Alcaligenaceae 28216|Betaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase DYD2_k127_5677805_24 1424334.W822_00750 2.226e-18 87.0 2BZD4@1|root,332J5@2|Bacteria,1RC8E@1224|Proteobacteria,2W1PD@28216|Betaproteobacteria,3T7GC@506|Alcaligenaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5677805_23 196490.AUEZ01000043_gene6927 2.812e-28 116.0 2AF3S@1|root,3152G@2|Bacteria,1PV19@1224|Proteobacteria,2V4HP@28211|Alphaproteobacteria,3K5ND@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5677805_3 1366050.N234_23870 5.508e-170 541.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2VS4Y@28216|Betaproteobacteria 28216|Betaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - - DYD2_k127_5677805_19 1125973.JNLC01000011_gene592 2.977e-63 231.0 COG0673@1|root,COG0673@2|Bacteria,1QSNV@1224|Proteobacteria,2TUMB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_5677805_18 1366050.N234_22440 7.929e-84 289.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP82@28216|Betaproteobacteria,1KD4A@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_5677805_2 977880.RALTA_A0669 2.569e-174 561.0 COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2VJYZ@28216|Betaproteobacteria,1KGJ3@119060|Burkholderiaceae 28216|Betaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.48 ko:K02182 - - - - ko00000,ko01000 - - - AMP-binding,AMP-binding_C DYD2_k127_5677805_28 331869.BAL199_17848 7.199e-06 51.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TUUN@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate - - 4.1.1.3 ko:K01003 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000 - - - PEP_mutase DYD2_k127_5683881_1 420324.KI912028_gene290 1.047e-35 138.0 COG0431@1|root,COG0431@2|Bacteria,1QU9C@1224|Proteobacteria,2TXAS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0655 Multimeric flavodoxin WrbA - - - - - - - - - - - - FMN_red DYD2_k127_5683881_8 595460.RRSWK_06191 7.246e-11 66.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD2_k127_5683881_4 251221.35210787 1.731e-24 108.0 COG5485@1|root,COG5485@2|Bacteria,1G6RM@1117|Cyanobacteria 1117|Cyanobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL DYD2_k127_5683881_2 640081.Dsui_2298 1.666e-33 134.0 COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria,2WEH8@28216|Betaproteobacteria,2KWT4@206389|Rhodocyclales 206389|Rhodocyclales S Thioesterase superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 DYD2_k127_5683881_3 1210884.HG799464_gene11143 6.098e-31 124.0 COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes 203682|Planctomycetes S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - - - - - - - - - - RRM_1 DYD2_k127_5683881_6 864073.HFRIS_006769 1.082e-17 94.0 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,474EF@75682|Oxalobacteraceae 28216|Betaproteobacteria M Belongs to the skp family ompH - - ko:K06142 - - - - ko00000 - - - OmpH DYD2_k127_5683881_5 1120956.JHZK01000002_gene1019 6.582e-23 110.0 COG1917@1|root,COG1917@2|Bacteria,1MYMN@1224|Proteobacteria,2UR93@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2 DYD2_k127_5683881_0 1123392.AQWL01000002_gene1753 8.571e-44 164.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,1KS7B@119069|Hydrogenophilales 119069|Hydrogenophilales F Ecdysteroid kinase - - - - - - - - - - - - APH DYD2_k127_570992_4 1038859.AXAU01000020_gene5398 5.916e-50 184.0 COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2TTXF@28211|Alphaproteobacteria,3JRB1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 DYD2_k127_570992_0 1205680.CAKO01000037_gene1338 1.442e-134 448.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TT4A@28211|Alphaproteobacteria,2JRFR@204441|Rhodospirillales 204441|Rhodospirillales C acyl-CoA transferases carnitine dehydratase - - - - - - - - - - - - CoA_transf_3 DYD2_k127_570992_1 1100720.ALKN01000035_gene991 3.206e-110 395.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2VTNQ@28216|Betaproteobacteria,4AGVD@80864|Comamonadaceae 28216|Betaproteobacteria S X-Pro dipeptidyl-peptidase domain protein - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD2_k127_570992_6 1336208.JADY01000027_gene2270 1.881e-08 57.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - TctC DYD2_k127_570992_2 1411123.JQNH01000001_gene1673 1.645e-105 351.0 COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria 28211|Alphaproteobacteria O PDZ DHR GLGF domain protein MA20_20705 - - - - - - - - - - - PDZ_2,Trypsin_2 DYD2_k127_570992_5 1071085.KK033114_gene736 5.352e-32 132.0 arCOG08934@1|root,arCOG08934@2157|Archaea,2XXBA@28890|Euryarchaeota 28890|Euryarchaeota Q carboxymuconolactone decarboxylase - - - - - - - - - - - - CMD DYD2_k127_570992_3 543728.Vapar_0801 1.627e-66 239.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJCY@28216|Betaproteobacteria,4ABM4@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_571474_2 29581.BW37_01859 3.769e-93 328.0 COG4585@1|root,COG4585@2|Bacteria,1RBN9@1224|Proteobacteria,2VQ8I@28216|Betaproteobacteria,47658@75682|Oxalobacteraceae 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 DYD2_k127_571474_3 1157708.KB907450_gene5841 1.605e-61 220.0 COG2197@1|root,COG2197@2|Bacteria,1RGN8@1224|Proteobacteria,2VRZK@28216|Betaproteobacteria,4AI0Z@80864|Comamonadaceae 28216|Betaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD2_k127_571474_6 330214.NIDE3825 7.597e-16 87.0 COG3417@1|root,COG3417@2|Bacteria 2|Bacteria M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) - - - ko:K07337 - - - - ko00000 - - - LpoB DYD2_k127_571474_5 330214.NIDE3825 6.471e-18 94.0 COG3417@1|root,COG3417@2|Bacteria 2|Bacteria M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) - - - ko:K07337 - - - - ko00000 - - - LpoB DYD2_k127_571474_0 460265.Mnod_1956 3.15e-150 486.0 COG0438@1|root,COG0438@2|Bacteria,1NJ19@1224|Proteobacteria,2TRT4@28211|Alphaproteobacteria,1JQQ6@119045|Methylobacteriaceae 28211|Alphaproteobacteria M glycosyl transferase group 1 expC - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_3,Glycos_transf_1 DYD2_k127_571474_4 1439940.BAY1663_03015 3.566e-59 213.0 COG2197@1|root,COG2197@2|Bacteria,1RGN8@1224|Proteobacteria 1224|Proteobacteria K Response regulator, receiver - - - - - - - - - - - - GerE,Response_reg DYD2_k127_571474_1 1463857.JOFZ01000001_gene5444 1.067e-144 484.0 COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria 201174|Actinobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 DYD2_k127_571474_7 1307761.L21SP2_3419 5.589e-15 76.0 COG0834@1|root,COG0834@2|Bacteria 2|Bacteria ET amino acid transport ehuB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD2_k127_5721988_32 1163617.SCD_n02123 1.788e-32 132.0 COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VV1S@28216|Betaproteobacteria 28216|Betaproteobacteria NU Type II transport protein GspH - - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl DYD2_k127_5721988_29 1163617.SCD_n02124 4.011e-39 151.0 COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria 28216|Betaproteobacteria NU type IV pilus modification protein PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl DYD2_k127_5721988_20 1163617.SCD_n02125 2.821e-79 278.0 COG4966@1|root,COG4966@2|Bacteria,1RH2G@1224|Proteobacteria,2VT5C@28216|Betaproteobacteria 28216|Betaproteobacteria NU Type IV Pilus-assembly protein W - - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW DYD2_k127_5721988_28 1163617.SCD_n02126 6.245e-43 168.0 COG4726@1|root,COG4726@2|Bacteria,1N9CE@1224|Proteobacteria,2VWPP@28216|Betaproteobacteria 28216|Betaproteobacteria NU Pilus assembly protein PilX - - - - - - - - - - - - - DYD2_k127_5721988_1 1485544.JQKP01000002_gene1376 0.0 1149.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,44V4V@713636|Nitrosomonadales 28216|Betaproteobacteria NU Neisseria PilC beta-propeller domain pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC DYD2_k127_5721988_34 247639.MGP2080_07554 1.01e-22 107.0 COG4968@1|root,COG4968@2|Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif pilE - - ko:K02655 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - ComP_DUS,N_methyl DYD2_k127_5721988_35 1283284.AZUK01000001_gene783 8.584e-22 102.0 COG4970@1|root,COG4970@2|Bacteria 2|Bacteria NU protein transport across the cell outer membrane fimT - - ko:K08084 - - - - ko00000,ko02044 3.A.15.2 - - GspH,N_methyl DYD2_k127_5721988_31 1157708.KB907460_gene1355 6.691e-34 138.0 COG4967@1|root,COG4967@2|Bacteria,1RK2M@1224|Proteobacteria,2VT1W@28216|Betaproteobacteria,4AEIG@80864|Comamonadaceae 28216|Betaproteobacteria NU type IV pilus modification protein PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl DYD2_k127_5721988_19 1095769.CAHF01000022_gene339 1.099e-80 290.0 COG4966@1|root,COG4966@2|Bacteria,1RC4Q@1224|Proteobacteria,2VS7N@28216|Betaproteobacteria,476YR@75682|Oxalobacteraceae 28216|Betaproteobacteria NU Type IV Pilus-assembly protein W pilW - - ko:K02672 - - - - ko00000,ko02035,ko02044 - - - N_methyl,PilW DYD2_k127_5721988_27 1502852.FG94_00626 5.361e-44 167.0 COG4726@1|root,COG4726@2|Bacteria,1N7I4@1224|Proteobacteria,2VVZB@28216|Betaproteobacteria,477AI@75682|Oxalobacteraceae 28216|Betaproteobacteria NU Pilus assembly protein PilX - - - - - - - - - - - - PilX_N DYD2_k127_5721988_2 1095769.CAHF01000022_gene341 1.779e-312 994.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VJEX@28216|Betaproteobacteria,476HV@75682|Oxalobacteraceae 28216|Betaproteobacteria NU Neisseria PilC beta-propeller domain pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC DYD2_k127_5721988_9 1163617.SCD_n02128 2.678e-146 473.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria 28216|Betaproteobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB DYD2_k127_5721988_25 1121035.AUCH01000007_gene495 5.157e-49 179.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,2KWMG@206389|Rhodocyclales 206389|Rhodocyclales M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 DYD2_k127_5721988_0 1095769.CAHF01000011_gene2717 0.0 1299.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,473U5@75682|Oxalobacteraceae 28216|Betaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS DYD2_k127_5721988_12 1266925.JHVX01000017_gene19 3.37e-125 408.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,371XT@32003|Nitrosomonadales 28216|Betaproteobacteria H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase DYD2_k127_5721988_22 1000565.METUNv1_02292 1.223e-67 238.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,2KW5R@206389|Rhodocyclales 28216|Betaproteobacteria H Tetrapyrrole (Corrin/Porphyrin) Methylases - - 2.1.1.107 ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - - TP_methylase DYD2_k127_5721988_26 1121935.AQXX01000129_gene1807 2.187e-46 174.0 COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,1S64S@1236|Gammaproteobacteria,1XKEY@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - - - - - - - - - - DUF934 DYD2_k127_5721988_4 257310.BB0397 1.844e-252 790.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,3T1UQ@506|Alcaligenaceae 28216|Betaproteobacteria C Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate cysI - 1.8.1.2,1.8.7.1 ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858,R00859,R03600 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr DYD2_k127_5721988_11 323848.Nmul_A1145 4.983e-131 424.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,37238@32003|Nitrosomonadales 28216|Betaproteobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD2_k127_5721988_17 1149133.ppKF707_3681 3.765e-90 303.0 COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,1SK0Z@1236|Gammaproteobacteria,1YDBQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 DYD2_k127_5721988_18 264730.PSPPH_0704 4.723e-89 301.0 COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,1TEUV@1236|Gammaproteobacteria,1Z8EG@136849|Pseudomonas syringae group 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 DYD2_k127_5721988_14 1217718.ALOU01000009_gene1061 2.841e-101 336.0 COG3638@1|root,COG3638@2|Bacteria,1MXYA@1224|Proteobacteria,2VM4F@28216|Betaproteobacteria,1KCPA@119060|Burkholderiaceae 28216|Betaproteobacteria P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran DYD2_k127_5721988_13 404589.Anae109_3021 1.341e-114 376.0 COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,43AKJ@68525|delta/epsilon subdivisions,2WQ9Y@28221|Deltaproteobacteria,2YVPI@29|Myxococcales 28221|Deltaproteobacteria P Bacterial extracellular solute-binding proteins, family 3 - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd DYD2_k127_5721988_5 228410.NE2405 1.028e-224 707.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,371XE@32003|Nitrosomonadales 28216|Betaproteobacteria U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN DYD2_k127_5721988_33 1123487.KB892835_gene3501 1.056e-25 109.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,2KWZ9@206389|Rhodocyclales 206389|Rhodocyclales J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p DYD2_k127_5721988_7 265072.Mfla_1710 6.798e-173 556.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,2KM17@206350|Nitrosomonadales 206350|Nitrosomonadales E PFAM Aminotransferase class-III argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_5721988_8 323848.Nmul_A1042 3.101e-159 507.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,371NM@32003|Nitrosomonadales 28216|Betaproteobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD2_k127_5721988_6 1288494.EBAPG3_13410 2.617e-216 676.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,371ZW@32003|Nitrosomonadales 28216|Betaproteobacteria F Belongs to the argininosuccinate synthase family. Type 1 subfamily argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth DYD2_k127_5721988_23 279714.FuraDRAFT_0774 2.289e-60 224.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,2KQYV@206351|Neisseriales 206351|Neisseriales S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 DYD2_k127_5721988_16 1163617.SCD_n02190 3.089e-90 302.0 COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria 28216|Betaproteobacteria F PFAM Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase DYD2_k127_5721988_24 1163617.SCD_n02191 2.119e-55 207.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria 28216|Betaproteobacteria S Aspartyl protease - - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas DYD2_k127_5721988_30 265072.Mfla_0384 2.369e-38 147.0 COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,2VUXZ@28216|Betaproteobacteria,2KN56@206350|Nitrosomonadales 206350|Nitrosomonadales O Rdx family - - - ko:K07401 - - - - ko00000 - - - Rdx DYD2_k127_5721988_21 296591.Bpro_1647 6.486e-73 259.0 COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,2WG0X@28216|Betaproteobacteria 28216|Betaproteobacteria P PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 DYD2_k127_5721988_10 290397.Adeh_2740 3.656e-140 457.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2YUHV@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 DYD2_k127_5721988_15 1122621.ATZA01000010_gene143 1.367e-94 314.0 COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,1IPBD@117747|Sphingobacteriia 976|Bacteroidetes H GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI DYD2_k127_5721988_3 228410.NE1161 6.071e-301 933.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,372IT@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C DYD2_k127_5740960_25 1163617.SCD_n00817 3.425e-43 161.0 COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria 28216|Betaproteobacteria K RNA polymerase sigE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_5740960_1 1288494.EBAPG3_4320 2.504e-319 983.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,372AD@32003|Nitrosomonadales 28216|Betaproteobacteria H TIGRFAM Acetolactate synthase, large subunit, biosynthetic ilvI - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_5740960_20 1288494.EBAPG3_4300 1.221e-76 273.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,3730Y@32003|Nitrosomonadales 28216|Betaproteobacteria E TIGRFAM Acetolactate synthase, small subunit ilvH GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5,ALS_ss_C DYD2_k127_5740960_6 1131553.JIBI01000060_gene709 3.144e-171 542.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,372TM@32003|Nitrosomonadales 28216|Betaproteobacteria F Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN DYD2_k127_5740960_14 228410.NE1322 2.974e-90 302.0 COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria,3728F@32003|Nitrosomonadales 28216|Betaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase DYD2_k127_5740960_13 1288494.EBAPG3_4280 4.496e-102 340.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,3725D@32003|Nitrosomonadales 28216|Betaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD2_k127_5740960_2 1288494.EBAPG3_4130 1.521e-263 819.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,371RP@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer DYD2_k127_5740960_29 580332.Slit_0390 4.061e-24 102.0 COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,2VW5A@28216|Betaproteobacteria 28216|Betaproteobacteria H Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 DYD2_k127_5740960_17 1095769.CAHF01000011_gene2564 4.466e-82 277.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2VJMC@28216|Betaproteobacteria,472YT@75682|Oxalobacteraceae 28216|Betaproteobacteria S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red DYD2_k127_5740960_12 1266925.JHVX01000003_gene674 4.466e-107 361.0 COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,372T0@32003|Nitrosomonadales 28216|Betaproteobacteria K Virulence factor BrkB rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB DYD2_k127_5740960_18 582744.Msip34_2278 8.752e-80 272.0 COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria,2KKV2@206350|Nitrosomonadales 206350|Nitrosomonadales M Transglycosylase SLT domain - - - - - - - - - - - - SLT DYD2_k127_5740960_3 1163617.SCD_n02117 2.369e-261 815.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit DYD2_k127_5740960_16 1163617.SCD_n02114 2.453e-83 287.0 COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria 28216|Betaproteobacteria E Spermidine synthase speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth DYD2_k127_5740960_15 1163617.SCD_n02113 3.004e-87 290.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria 28216|Betaproteobacteria L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX DYD2_k127_5740960_23 637389.Acaty_c0522 1.615e-59 216.0 2F2KZ@1|root,33VHM@2|Bacteria,1NV1E@1224|Proteobacteria,1SN95@1236|Gammaproteobacteria,2NCKP@225057|Acidithiobacillales 225057|Acidithiobacillales - - - - - - - - - - - - - - - DYD2_k127_5740960_19 748247.AZKH_1050 1.056e-76 258.0 COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,2KYR2@206389|Rhodocyclales 206389|Rhodocyclales C Rubrerythrin - - - - - - - - - - - - Rubrerythrin DYD2_k127_5740960_4 1123393.KB891327_gene345 4.095e-230 719.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VJ6T@28216|Betaproteobacteria,1KT09@119069|Hydrogenophilales 119069|Hydrogenophilales C Cysteine-rich domain - - - - - - - - - - - - CCG DYD2_k127_5740960_21 1288494.EBAPG3_16120 2.42e-76 262.0 COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,2VQUX@28216|Betaproteobacteria,372TE@32003|Nitrosomonadales 28216|Betaproteobacteria C Protein of unknown function (DUF3501) - - - - - - - - - - - - DUF3501 DYD2_k127_5740960_10 265072.Mfla_1678 1.587e-136 446.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,2KKF7@206350|Nitrosomonadales 206350|Nitrosomonadales M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS DYD2_k127_5740960_28 1163617.SCD_n02110 3.488e-33 138.0 2B1HQ@1|root,31TYQ@2|Bacteria,1MYSE@1224|Proteobacteria,2VTMU@28216|Betaproteobacteria 28216|Betaproteobacteria S CNP1-like family - - - - - - - - - - - - CNP1 DYD2_k127_5740960_7 323848.Nmul_A1843 3.249e-170 541.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,3722B@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA DYD2_k127_5740960_8 1288494.EBAPG3_16180 4.364e-159 509.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,372GQ@32003|Nitrosomonadales 28216|Betaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 DYD2_k127_5740960_27 323848.Nmul_A1816 1.49e-36 139.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,373IF@32003|Nitrosomonadales 28216|Betaproteobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 DYD2_k127_5740960_26 264198.Reut_A2958 2.086e-41 159.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,1K7RK@119060|Burkholderiaceae 28216|Betaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p DYD2_k127_5740960_11 1163617.SCD_n02105 1.7e-131 430.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria 28216|Betaproteobacteria H Belongs to the FPP GGPP synthase family ispB - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt DYD2_k127_5740960_30 887062.HGR_12202 4.44e-12 68.0 2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,4AFKE@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - ko:K06950 - - - - ko00000 - - - - DYD2_k127_5740960_9 261292.Nit79A3_2376 8.147e-138 457.0 COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,2WGR4@28216|Betaproteobacteria,372VJ@32003|Nitrosomonadales 28216|Betaproteobacteria T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 DYD2_k127_5740960_5 1163617.SCD_n02101 6.857e-176 562.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria 28216|Betaproteobacteria T response regulator pilR - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat DYD2_k127_5740960_22 1266925.JHVX01000009_gene44 3.034e-73 252.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,3731N@32003|Nitrosomonadales 28216|Betaproteobacteria V N-acetylmuramoyl-L-alanine amidase (Family 2) ampD GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 ko:K03806 - - - - ko00000,ko01000,ko01011 - - - Amidase_2 DYD2_k127_5740960_0 323848.Nmul_A2468 0.0 1440.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,372QB@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdA GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN DYD2_k127_5740960_31 477974.Daud_0494 5.353e-12 78.0 arCOG08693@1|root,339YK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_5740960_24 323848.Nmul_A2469 1.809e-44 176.0 COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,371XR@32003|Nitrosomonadales 28216|Betaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm DYD2_k127_5745811_0 631362.Thi970DRAFT_04077 2.156e-300 930.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales 135613|Chromatiales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD2_k127_5745811_5 1125863.JAFN01000001_gene3237 1.15e-94 317.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - iAF987.Gmet_1716 ECH_1 DYD2_k127_5745811_4 1540221.JQNI01000002_gene2661 2.639e-97 325.0 COG1028@1|root,COG1028@2|Bacteria,1WJ80@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD2_k127_5745811_1 1348657.M622_00515 4.527e-256 803.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KV59@206389|Rhodocyclales 206389|Rhodocyclales I poly(R)-hydroxyalkanoic acid synthase - - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N DYD2_k127_5745811_11 998088.B565_2051 9.752e-35 137.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,1Y5V7@135624|Aeromonadales 135624|Aeromonadales K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 DYD2_k127_5745811_3 1121033.AUCF01000032_gene2640 8.448e-189 598.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,2JPCY@204441|Rhodospirillales 204441|Rhodospirillales I COG1960 Acyl-CoA dehydrogenases - - 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_5745811_6 1242864.D187_005143 7.617e-79 276.0 COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions 1224|Proteobacteria S 2-nitropropane dioxygenase npd - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO DYD2_k127_5745811_8 1454004.AW11_03897 6.207e-74 256.0 COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2VQJ1@28216|Betaproteobacteria,1KQTA@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria Q DSBA-like thioredoxin domain - - 5.99.1.4 ko:K14584 ko00626,ko01100,ko01120,ko01220,map00626,map01100,map01120,map01220 M00534 R05137 RC03084 br01602,ko00000,ko00001,ko00002,ko01000 - - - DSBA DYD2_k127_5745811_10 452637.Oter_0268 1.301e-63 222.0 COG2110@1|root,COG2110@2|Bacteria,46SV0@74201|Verrucomicrobia 74201|Verrucomicrobia S Appr-1'-p processing enzyme - - - - - - - - - - - - Macro DYD2_k127_5745811_2 1123261.AXDW01000019_gene724 4.84e-256 799.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,1X4BD@135614|Xanthomonadales 135614|Xanthomonadales I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD2_k127_5745811_7 269799.Gmet_3291 2.815e-77 267.0 COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,42S4C@68525|delta/epsilon subdivisions,2WNXY@28221|Deltaproteobacteria,43T1V@69541|Desulfuromonadales 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD2_k127_5745811_9 1528106.JRJE01000004_gene622 7.314e-72 256.0 COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,2JPU7@204441|Rhodospirillales 204441|Rhodospirillales E COG0119 Isopropylmalate homocitrate citramalate synthases - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like DYD2_k127_5754105_2 583345.Mmol_1193 7.367e-73 252.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VJ2Y@28216|Betaproteobacteria,2KM6X@206350|Nitrosomonadales 206350|Nitrosomonadales NU PFAM type II secretion system - - - ko:K12278 - - - - ko00000,ko02044 - - - T2SSF DYD2_k127_5754105_0 1163617.SCD_n02686 1.091e-237 749.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria 28216|Betaproteobacteria NU type II secretion system protein E - - - ko:K02454,ko:K02652,ko:K12276 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - T2SSE,T2SSE_N DYD2_k127_5754105_1 323848.Nmul_A1126 5.7e-111 367.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,371NF@32003|Nitrosomonadales 28216|Betaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N DYD2_k127_5754105_4 522306.CAP2UW1_1509 8.59e-41 162.0 COG3807@1|root,COG3807@2|Bacteria,1MZIA@1224|Proteobacteria,2VUTD@28216|Betaproteobacteria,1KR4F@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S Bacterial SH3 domain - - - - - - - - - - - - SH3_4 DYD2_k127_5754105_3 582744.Msip34_0554 1.172e-48 178.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,2KMSR@206350|Nitrosomonadales 206350|Nitrosomonadales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB DYD2_k127_5754105_6 557598.LHK_02837 5.793e-28 117.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,2KS2I@206351|Neisseriales 206351|Neisseriales O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin DYD2_k127_5754105_5 265072.Mfla_2187 8.063e-33 132.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KN1N@206350|Nitrosomonadales 206350|Nitrosomonadales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese DYD2_k127_5765057_5 631454.N177_2966 6.084e-36 142.0 COG3090@1|root,COG3090@2|Bacteria,1RD4B@1224|Proteobacteria,2U8B7@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD2_k127_5765057_0 631454.N177_2965 4.679e-186 591.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,1JPMN@119043|Rhodobiaceae 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM DYD2_k127_5765057_1 631454.N177_2964 5.096e-105 350.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TS46@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component dctP - - ko:K11688 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctP DYD2_k127_5765057_2 795666.MW7_2355 1.868e-104 361.0 COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,1K2XV@119060|Burkholderiaceae 28216|Betaproteobacteria EH Belongs to the TPP enzyme family - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_5765057_4 1538295.JY96_01510 8.458e-45 165.0 COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2VSN3@28216|Betaproteobacteria,1KM4X@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2237) - - - ko:K09966 - - - - ko00000 - - - DUF2237 DYD2_k127_5765057_3 688245.CtCNB1_2693 1.462e-51 183.0 COG0655@1|root,COG0655@2|Bacteria,1RAP5@1224|Proteobacteria,2VQVY@28216|Betaproteobacteria,4AK1I@80864|Comamonadaceae 28216|Betaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red DYD2_k127_5771196_37 631454.N177_2966 0.0005123 43.0 COG3090@1|root,COG3090@2|Bacteria,1RD4B@1224|Proteobacteria,2U8B7@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD2_k127_5771196_18 323848.Nmul_A1099 6.135e-88 292.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,371MN@32003|Nitrosomonadales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 DYD2_k127_5771196_32 649638.Trad_0765 1.651e-16 91.0 COG1196@1|root,COG1652@1|root,COG1196@2|Bacteria,COG1652@2|Bacteria,1WN78@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus D COGs COG1196 Chromosome segregation ATPase - - - - - - - - - - - - LysM DYD2_k127_5771196_2 631454.N177_1485 3.667e-213 673.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,1JPNI@119043|Rhodobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_5771196_28 314256.OG2516_00664 1.678e-31 130.0 2EQV8@1|root,33IF1@2|Bacteria,1NKPY@1224|Proteobacteria 1224|Proteobacteria S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB DYD2_k127_5771196_16 631454.N177_1483 5.223e-100 336.0 COG3181@1|root,COG3181@2|Bacteria,1PGFD@1224|Proteobacteria,2URTK@28211|Alphaproteobacteria,1JQD2@119043|Rhodobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_5771196_30 1454004.AW11_00603 8.043e-24 106.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,2VW2I@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 DYD2_k127_5771196_36 4155.Migut.N00303.1.p 3.033e-05 53.0 COG0698@1|root,2QS8W@2759|Eukaryota,37QE0@33090|Viridiplantae,3GAXS@35493|Streptophyta,44IRQ@71274|asterids 35493|Streptophyta G DNA-damage-repair toleration protein DRT102 - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - - - - - - - - - - Cupin_2,Cupin_7,LacAB_rpiB DYD2_k127_5771196_5 1429916.X566_14890 6.759e-153 490.0 COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria,3K3FV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase DYD2_k127_5771196_27 1380355.JNIJ01000013_gene367 7.937e-32 131.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity mce - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 DYD2_k127_5771196_22 375286.mma_0959 1.103e-50 193.0 COG4977@1|root,COG4977@2|Bacteria,1R8XV@1224|Proteobacteria,2VKI6@28216|Betaproteobacteria 28216|Betaproteobacteria K Cupin - - - - - - - - - - - - Cupin_6,HTH_18 DYD2_k127_5771196_13 163908.KB235896_gene4823 2.933e-108 353.0 COG1335@1|root,COG1335@2|Bacteria,1G3QK@1117|Cyanobacteria 1117|Cyanobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase DYD2_k127_5771196_0 1121405.dsmv_1320 0.0 1162.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales 28221|Deltaproteobacteria G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N DYD2_k127_5771196_1 62928.azo3546 6.462e-259 804.0 COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,2VKEK@28216|Betaproteobacteria 28216|Betaproteobacteria E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues ctaQ - 3.4.17.19 ko:K01299 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M32 DYD2_k127_5771196_12 319003.Bra1253DRAFT_08243 2.862e-109 368.0 COG2223@1|root,COG2223@2|Bacteria,1QW6R@1224|Proteobacteria,2TWQ6@28211|Alphaproteobacteria,3K6KW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Major Facilitator Superfamily MA20_36660 - - - - - - - - - - - MFS_1 DYD2_k127_5771196_10 1123023.JIAI01000001_gene6533 9.069e-113 375.0 COG3384@1|root,COG3384@2|Bacteria,2GJDG@201174|Actinobacteria 201174|Actinobacteria S PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - - - - - - - - - - LigB DYD2_k127_5771196_31 1218084.BBJK01000142_gene7359 6.948e-17 93.0 COG0662@1|root,COG0662@2|Bacteria,1QU63@1224|Proteobacteria,2VNQW@28216|Betaproteobacteria,1K6YY@119060|Burkholderiaceae 28216|Betaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_5771196_29 266779.Meso_3537 7.287e-27 124.0 COG0662@1|root,COG0662@2|Bacteria,1QU63@1224|Proteobacteria,2TW18@28211|Alphaproteobacteria,43Q5D@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_5771196_21 358220.C380_12010 3.932e-55 203.0 COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2VT72@28216|Betaproteobacteria,4AED9@80864|Comamonadaceae 28216|Betaproteobacteria S transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp DYD2_k127_5771196_20 1502852.FG94_04682 9.856e-62 216.0 COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2VSDD@28216|Betaproteobacteria,474JP@75682|Oxalobacteraceae 28216|Betaproteobacteria S transporter component - - - ko:K07112 - - - - ko00000 - - - Sulf_transp DYD2_k127_5771196_34 502025.Hoch_6246 8.552e-12 74.0 COG3751@1|root,COG3751@2|Bacteria 2|Bacteria O 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_5 DYD2_k127_5771196_7 426114.THI_3126 4.025e-136 460.0 COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,2VHX5@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - 2.7.13.1 ko:K05962 - - - - ko00000,ko01000 - - - HAMP,HATPase_c,HisKA DYD2_k127_5771196_11 1163617.SCD_n01435 2.505e-111 365.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI0K@28216|Betaproteobacteria 28216|Betaproteobacteria K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C DYD2_k127_5771196_35 1267005.KB911262_gene3213 1.735e-10 70.0 2DNEG@1|root,32X40@2|Bacteria,1R7P4@1224|Proteobacteria,2UCRV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S LTXXQ motif family protein - - - - - - - - - - - - LTXXQ DYD2_k127_5771196_3 1137269.AZWL01000001_gene5348 1.939e-211 670.0 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria 201174|Actinobacteria IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - AMP-binding,AMP-binding_C DYD2_k127_5771196_4 1137269.AZWL01000001_gene5347 6.711e-176 569.0 COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria 201174|Actinobacteria I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_5771196_15 1137269.AZWL01000001_gene5346 3.797e-101 335.0 COG1024@1|root,COG1024@2|Bacteria,2ID1V@201174|Actinobacteria 201174|Actinobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD2_k127_5771196_14 1169161.KB897740_gene2296 7.916e-103 355.0 COG0346@1|root,COG0346@2|Bacteria,2I9RU@201174|Actinobacteria 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase_4 DYD2_k127_5771196_9 1169161.KB897740_gene2297 1.059e-118 392.0 COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria 201174|Actinobacteria I acyl-CoA dehydrogenase - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_N DYD2_k127_5771196_17 748247.AZKH_p0420 8.513e-92 306.0 28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2VQ6Y@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5771196_19 748247.AZKH_p0116 2.211e-70 239.0 COG3631@1|root,COG3631@2|Bacteria,1PT2G@1224|Proteobacteria,2WA86@28216|Betaproteobacteria,2KYWR@206389|Rhodocyclales 206389|Rhodocyclales S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL_2 DYD2_k127_5771196_6 522306.CAP2UW1_2978 1.294e-136 438.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11 DYD2_k127_5771196_24 105559.Nwat_0425 3.917e-44 176.0 2A6YK@1|root,30VTJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - NTP_transf_2 DYD2_k127_5771196_8 666684.AfiDRAFT_3149 3.023e-123 399.0 COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2TVF5@28211|Alphaproteobacteria,3JXK5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 DYD2_k127_5771196_26 1146883.BLASA_3563 2.505e-35 151.0 COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria,4EVMS@85013|Frankiales 201174|Actinobacteria CO Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - DYD2_k127_5771196_23 1041146.ATZB01000032_gene455 1.391e-45 169.0 COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,4BETD@82115|Rhizobiaceae 28211|Alphaproteobacteria S YHS domain - - - - - - - - - - - - YHS DYD2_k127_57955_0 1288494.EBAPG3_23000 2.561e-128 417.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,371U2@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM DYD2_k127_57955_2 62928.azo0183 1.692e-78 269.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,2KW5V@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB - 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB DYD2_k127_57955_1 1219049.SP5_090_00220 1.593e-80 274.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2UP5V@28211|Alphaproteobacteria,2KDJW@204457|Sphingomonadales 204457|Sphingomonadales S Predicted membrane protein (DUF2238) - - - - - - - - - - - - DUF2238 DYD2_k127_57955_6 485913.Krac_4615 0.0001872 48.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - - - - - - - - - - - AhpC-TSA DYD2_k127_57955_4 485913.Krac_4615 3.736e-23 102.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - - - - - - - - - - - AhpC-TSA DYD2_k127_57955_3 580332.Slit_0724 2.688e-31 125.0 COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,44W1W@713636|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF493) ybeD - - ko:K09158 - - - - ko00000 - - - DUF493 DYD2_k127_5820790_5 1163617.SCD_n00736 4.017e-60 209.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria 28216|Betaproteobacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD2_k127_5820790_6 1000565.METUNv1_02527 2.083e-54 192.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,2KWJV@206389|Rhodocyclales 206389|Rhodocyclales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions fdxA - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4,Fer4_4 DYD2_k127_5820790_1 1163617.SCD_n00737 2.477e-239 770.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria 28216|Betaproteobacteria L PD-(D/E)XK nuclease superfamily addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 DYD2_k127_5820790_0 1163617.SCD_n00738 0.0 1075.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria 28216|Betaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA addA - 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C DYD2_k127_5820790_3 322710.Avin_21330 8.05e-94 318.0 COG2175@1|root,COG2175@2|Bacteria,1P6UZ@1224|Proteobacteria,1T14G@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Taurine catabolism dioxygenase TauD, TfdA family - - 1.14.11.17 ko:K03119 ko00430,ko00920,map00430,map00920 - R05320 RC01331 ko00000,ko00001,ko01000 - - - TauD DYD2_k127_5820790_7 1210884.HG799463_gene9341 1.182e-07 58.0 COG2128@1|root,COG2128@2|Bacteria,2IZ92@203682|Planctomycetes 203682|Planctomycetes S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD2_k127_5820790_8 377629.TERTU_3523 1.893e-05 50.0 COG2128@1|root,COG2128@2|Bacteria,1RASD@1224|Proteobacteria,1S391@1236|Gammaproteobacteria,2PNWX@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD2_k127_5820790_4 1231391.AMZF01000037_gene581 5.71e-86 298.0 COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2W1GT@28216|Betaproteobacteria,3T5D6@506|Alcaligenaceae 28216|Betaproteobacteria IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short_C2 DYD2_k127_5820790_2 1231391.AMZF01000037_gene582 5.992e-199 627.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VMVH@28216|Betaproteobacteria,3T60M@506|Alcaligenaceae 28216|Betaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine - - 1.1.1.308 ko:K15509 - - - - ko00000,ko01000 - - - Histidinol_dh DYD2_k127_5821680_2 1163617.SCD_n02478 9.522e-148 472.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria 28216|Betaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC DYD2_k127_5821680_11 1163617.SCD_n02477 1.256e-07 55.0 2DFW3@1|root,2ZTE4@2|Bacteria,1P8GA@1224|Proteobacteria,2W65E@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5821680_12 1458357.BG58_35530 2.443e-07 58.0 COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,2VWI9@28216|Betaproteobacteria,1K86K@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 DYD2_k127_5821680_6 1288494.EBAPG3_28070 1.405e-108 362.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,371UP@32003|Nitrosomonadales 28216|Betaproteobacteria M Peptidase family M23 - - 3.4.24.75 ko:K08259 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 DYD2_k127_5821680_0 1288494.EBAPG3_28060 0.0 1312.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,371QF@32003|Nitrosomonadales 28216|Betaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD2_k127_5821680_1 1163617.SCD_n02472 1.099e-165 530.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria 28216|Betaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ DYD2_k127_5821680_4 1266925.JHVX01000004_gene1159 1.03e-119 391.0 COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,37209@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF815) - - - ko:K06923 - - - - ko00000 - - - DUF815 DYD2_k127_5821680_5 1163617.SCD_n02471 4.011e-116 389.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria 28216|Betaproteobacteria L Belongs to the Nudix hydrolase family mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,TMP-TENI DYD2_k127_5821680_8 1009370.ALO_06035 2.538e-88 302.0 COG1052@1|root,COG1052@2|Bacteria,1TS88@1239|Firmicutes,4H4FD@909932|Negativicutes 909932|Negativicutes CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_5821680_10 1235457.C404_18890 2.999e-19 95.0 COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,1KA41@119060|Burkholderiaceae 28216|Betaproteobacteria S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase yacG - - ko:K09862 - - - - ko00000 - - - YacG DYD2_k127_5821680_7 1454004.AW11_02297 2.903e-96 321.0 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,1KQ0R@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity zapD - - ko:K18778 - - - - ko00000,ko03036 - - - ZapD DYD2_k127_5821680_9 323848.Nmul_A2130 2.495e-58 210.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,372ZV@32003|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE DYD2_k127_5821680_3 1123367.C666_04905 9.121e-121 393.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,2KVU7@206389|Rhodocyclales 206389|Rhodocyclales NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 DYD2_k127_583409_4 1485544.JQKP01000017_gene610 5.162e-96 321.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,44VE7@713636|Nitrosomonadales 28216|Betaproteobacteria I Squalene/phytoene synthase hpnC - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY DYD2_k127_583409_5 1550091.JROE01000007_gene2800 4.313e-05 48.0 2DT5I@1|root,33IT8@2|Bacteria,4NZMY@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_583409_1 1288494.EBAPG3_26760 8.515e-157 508.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,371ZV@32003|Nitrosomonadales 28216|Betaproteobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N DYD2_k127_583409_3 1163617.SCD_n01773 4.905e-105 344.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria 28216|Betaproteobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease DYD2_k127_583409_0 1163617.SCD_n01772 3.757e-231 720.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria 28216|Betaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX DYD2_k127_583409_2 757424.Hsero_2580 5.033e-113 368.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,473C8@75682|Oxalobacteraceae 28216|Betaproteobacteria O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD2_k127_5922857_2 395493.BegalDRAFT_2350 6.219e-22 98.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,460R1@72273|Thiotrichales 72273|Thiotrichales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 DYD2_k127_5922857_0 1123392.AQWL01000002_gene1978 0.0 1314.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSKV@119069|Hydrogenophilales 119069|Hydrogenophilales V MMPL family - - - - - - - - - - - - ACR_tran DYD2_k127_5922857_1 886293.Sinac_4588 3.745e-105 352.0 COG0265@1|root,COG0265@2|Bacteria,2IYN3@203682|Planctomycetes 203682|Planctomycetes O Trypsin - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD2_k127_5933180_58 667632.KB890169_gene5035 1.414e-32 127.0 COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,2VUAP@28216|Betaproteobacteria,1K8TQ@119060|Burkholderiaceae 28216|Betaproteobacteria P Rieske-like [2Fe-2S] domain - - - ko:K05710,ko:K18087 ko00360,ko00621,ko01100,ko01120,ko01220,map00360,map00621,map01100,map01120,map01220 M00543,M00545 R05261,R05262,R05263,R05264,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske,Rieske_2 DYD2_k127_5933180_24 323848.Nmul_A0701 1.449e-82 278.0 COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2VQ83@28216|Betaproteobacteria,371PF@32003|Nitrosomonadales 28216|Betaproteobacteria O Scaffold protein Nfu/NifU N terminal - - - - - - - - - - - - Nfu_N,NifU DYD2_k127_5933180_32 1266925.JHVX01000003_gene432 7.298e-69 239.0 COG0822@1|root,COG0822@2|Bacteria,1PC9F@1224|Proteobacteria,2VS65@28216|Betaproteobacteria,372KK@32003|Nitrosomonadales 28216|Betaproteobacteria C NifU-like N terminal domain - - - ko:K04488 - - - - ko00000 - - - NifU_N DYD2_k127_5933180_5 1266925.JHVX01000003_gene433 3.652e-202 640.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,371MB@32003|Nitrosomonadales 28216|Betaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 DYD2_k127_5933180_11 1288494.EBAPG3_310 1.305e-140 466.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2VMJ9@28216|Betaproteobacteria,372PT@32003|Nitrosomonadales 28216|Betaproteobacteria O Uncharacterized protein family (UPF0051) sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 DYD2_k127_5933180_15 1288494.EBAPG3_320 9.431e-122 404.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2VNGT@28216|Betaproteobacteria,371MH@32003|Nitrosomonadales 28216|Betaproteobacteria O ABC transporter sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran DYD2_k127_5933180_2 1382359.JIAL01000001_gene678 9.397e-237 739.0 COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria 57723|Acidobacteria O Uncharacterized protein family (UPF0051) - - - ko:K09014 - - - - ko00000 - - - UPF0051 DYD2_k127_5933180_50 1266925.JHVX01000003_gene437 3.547e-44 163.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,373A6@32003|Nitrosomonadales 28216|Betaproteobacteria S Belongs to the HesB IscA family iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn DYD2_k127_5933180_8 1288494.EBAPG3_600 6.283e-142 468.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,371RC@32003|Nitrosomonadales 28216|Betaproteobacteria E PFAM Aminotransferase, class V - - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 DYD2_k127_5933180_36 1266925.JHVX01000003_gene438 3.227e-64 223.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,3732A@32003|Nitrosomonadales 28216|Betaproteobacteria K Transcriptional regulator iscR - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 DYD2_k127_5933180_19 580332.Slit_2257 3.47e-105 346.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,44VK5@713636|Nitrosomonadales 28216|Betaproteobacteria E Bacterial transferase hexapeptide (six repeats) - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep DYD2_k127_5933180_30 497321.C664_00090 1.098e-72 252.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,2KW30@206389|Rhodocyclales 206389|Rhodocyclales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD2_k127_5933180_17 1288494.EBAPG3_640 1.127e-114 390.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,372NY@32003|Nitrosomonadales 28216|Betaproteobacteria G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P DYD2_k127_5933180_67 5888.CAK57676 8.511e-06 56.0 COG0013@1|root,KOG1155@2759|Eukaryota,3ZBBC@5878|Ciliophora 5878|Ciliophora DO Anaphase promoting complex subunit 8 / Cdc23 - - - ko:K03355 ko04110,ko04111,ko04113,ko04114,ko04120,ko04914,ko05166,map04110,map04111,map04113,map04114,map04120,map04914,map05166 M00389 - - ko00000,ko00001,ko00002,ko03036,ko04121 - - - ANAPC8,TPR_1,TPR_8 DYD2_k127_5933180_41 391165.GbCGDNIH1_0516 2.41e-57 222.0 COG0596@1|root,COG0596@2|Bacteria,1Q6ET@1224|Proteobacteria,2URHM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S alpha/beta hydrolase fold - - 3.3.2.9 ko:K01253 ko00980,ko04976,ko05204,map00980,map04976,map05204 - R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443 RC01447,RC01728,RC01764,RC02528 ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_6 DYD2_k127_5933180_46 313606.M23134_04297 6.46e-52 200.0 28J0S@1|root,2Z8XX@2|Bacteria,4P2J4@976|Bacteroidetes,47X8E@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5933180_47 411902.CLOBOL_02063 1.037e-51 199.0 COG1073@1|root,COG1073@2|Bacteria,1TRSD@1239|Firmicutes 1239|Firmicutes S Belongs to the UPF0255 family - - - - - - - - - - - - DUF1100 DYD2_k127_5933180_1 323848.Nmul_A0670 0.0 1056.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,3729D@32003|Nitrosomonadales 28216|Betaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V DYD2_k127_5933180_7 472759.Nhal_1248 3.212e-145 477.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1WW0B@135613|Chromatiales 135613|Chromatiales P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD2_k127_5933180_40 1288494.EBAPG3_680 8.64e-60 214.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,37313@32003|Nitrosomonadales 28216|Betaproteobacteria G Peptidyl-prolyl cis-trans isomerase slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C DYD2_k127_5933180_42 1163617.SCD_n01247 1.503e-56 206.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria 28216|Betaproteobacteria O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD2_k127_5933180_16 323848.Nmul_A1143 2.2e-120 398.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,372A3@32003|Nitrosomonadales 28216|Betaproteobacteria S A domain family that is part of the cupin metalloenzyme superfamily. ycfD - 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 DYD2_k127_5933180_61 1163617.SCD_n01246 5.203e-29 122.0 2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5933180_21 1163617.SCD_n01245 1.058e-87 303.0 COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM beta-lactamase domain protein - - - - - - - - - - - - Lactamase_B_2 DYD2_k127_5933180_12 522306.CAP2UW1_1373 1.433e-130 428.0 COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,1KQGR@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M NlpB/DapX lipoprotein nlpB - - ko:K07287 - - - - ko00000,ko02000 1.B.33.1 - - Lipoprotein_18 DYD2_k127_5933180_10 1163617.SCD_n01243 1.072e-140 452.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria 28216|Betaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD2_k127_5933180_39 196367.JNFG01000202_gene2511 6.195e-62 218.0 COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,2VR4M@28216|Betaproteobacteria,1K2UH@119060|Burkholderiaceae 28216|Betaproteobacteria H Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,TehB DYD2_k127_5933180_49 395492.Rleg2_0648 6.435e-48 174.0 COG2329@1|root,COG2329@2|Bacteria,1RGVV@1224|Proteobacteria,2U9A3@28211|Alphaproteobacteria,4BEPI@82115|Rhizobiaceae 28211|Alphaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM DYD2_k127_5933180_3 414684.RC1_1718 1.799e-209 661.0 COG5310@1|root,COG5310@2|Bacteria,1MUZB@1224|Proteobacteria,2TRTR@28211|Alphaproteobacteria,2JR46@204441|Rhodospirillales 204441|Rhodospirillales Q Homospermidine synthase hss - 2.5.1.44 ko:K00808 ko00960,ko01110,map00960,map01110 - R00018 RC00053 ko00000,ko00001,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP DYD2_k127_5933180_6 713586.KB900536_gene957 1.455e-184 588.0 COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,1T3J1@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases - - 1.1.1.1,1.2.1.10,1.2.1.87 ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927,R09097 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh DYD2_k127_5933180_9 1411123.JQNH01000001_gene3804 8.111e-142 461.0 COG0045@1|root,COG0045@2|Bacteria,1R3UY@1224|Proteobacteria,2TVQC@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the succinate malate CoA ligase beta subunit family - - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA DYD2_k127_5933180_14 1469245.JFBG01000027_gene1475 5.668e-124 403.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1WW8G@135613|Chromatiales 1236|Gammaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA DYD2_k127_5933180_27 518766.Rmar_0120 9.494e-75 256.0 COG0500@1|root,COG0500@2|Bacteria,4PM8S@976|Bacteroidetes 976|Bacteroidetes Q PFAM Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_12,Methyltransf_25,Methyltransf_31,NodS DYD2_k127_5933180_69 406327.Mevan_1320 4.3e-05 53.0 COG1553@1|root,arCOG02068@2157|Archaea,2XYJ8@28890|Euryarchaeota,23R0A@183939|Methanococci 183939|Methanococci P PFAM DsrE family protein - - - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE DYD2_k127_5933180_44 570952.ATVH01000016_gene2337 2.416e-54 200.0 COG1595@1|root,COG1595@2|Bacteria,1NRNT@1224|Proteobacteria,2TT5K@28211|Alphaproteobacteria,2JZNH@204441|Rhodospirillales 204441|Rhodospirillales K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_5933180_65 1255043.TVNIR_0147 3.038e-13 72.0 COG5662@1|root,COG5662@2|Bacteria 2|Bacteria K AntiSigma factor rsrA GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - - - - - - - - - - zf-HC2 DYD2_k127_5933180_23 1211115.ALIQ01000156_gene4412 7.186e-83 298.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2TR8A@28211|Alphaproteobacteria,3NCSX@45404|Beijerinckiaceae 28211|Alphaproteobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 DYD2_k127_5933180_26 1123024.AUII01000052_gene3914 7.902e-75 268.0 COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales 201174|Actinobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_31 DYD2_k127_5933180_34 331869.BAL199_29922 2.717e-66 230.0 COG5553@1|root,COG5553@2|Bacteria,1RD6A@1224|Proteobacteria,2U7HF@28211|Alphaproteobacteria,4BT3J@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S metal-dependent enzyme of the double-stranded beta helix superfamily - - - - - - - - - - - - - DYD2_k127_5933180_59 420662.Mpe_A3396 7.364e-31 131.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1RG0B@1224|Proteobacteria,2WFG8@28216|Betaproteobacteria,1KNDT@119065|unclassified Burkholderiales 28216|Betaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 DYD2_k127_5933180_45 757424.Hsero_4151 3.511e-53 196.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,473BA@75682|Oxalobacteraceae 28216|Betaproteobacteria S Involved in biogenesis of respiratory and photosynthetic systems senC - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD2_k127_5933180_55 1280948.HY36_16135 4.171e-36 143.0 2CBRD@1|root,32RTX@2|Bacteria,1R5XB@1224|Proteobacteria,2U1IV@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5933180_57 292415.Tbd_2559 1.627e-33 136.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KS2S@119069|Hydrogenophilales 119069|Hydrogenophilales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps - - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 DYD2_k127_5933180_35 402626.Rpic_1791 6.522e-66 231.0 COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2VJHR@28216|Betaproteobacteria,1K76Q@119060|Burkholderiaceae 28216|Betaproteobacteria C cytochrome - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C DYD2_k127_5933180_18 296591.Bpro_3503 2.907e-108 358.0 COG4447@1|root,COG4447@2|Bacteria,1R66K@1224|Proteobacteria,2VNEG@28216|Betaproteobacteria 28216|Betaproteobacteria M cellulose binding - - - - - - - - - - - - - DYD2_k127_5933180_29 319003.Bra1253DRAFT_07770 8.594e-73 250.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,3JZZ9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CO Redoxin - - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin DYD2_k127_5933180_48 1057002.KB905370_gene643 1.776e-50 186.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,4BECI@82115|Rhizobiaceae 28211|Alphaproteobacteria CO Thioredoxin-like tlpA - - - - - - - - - - - AhpC-TSA,Redoxin DYD2_k127_5933180_20 880073.Calab_1013 1.717e-104 362.0 COG2132@1|root,COG2132@2|Bacteria,2NP9C@2323|unclassified Bacteria 2|Bacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD2_k127_5933180_22 1525715.IX54_05070 1.344e-86 293.0 COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,2PYNF@265|Paracoccus 28211|Alphaproteobacteria O Cytochrome C biogenesis protein transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD DYD2_k127_5933180_31 1267533.KB906733_gene3555 1.649e-72 250.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 DYD2_k127_5933180_38 1499967.BAYZ01000076_gene830 2.42e-63 227.0 COG1651@1|root,COG1651@2|Bacteria 2|Bacteria O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - - - - - - - - - - Thioredoxin_4 DYD2_k127_5933180_52 1125863.JAFN01000001_gene2229 8.038e-44 164.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,42UF2@68525|delta/epsilon subdivisions,2WQGZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria K MerR, DNA binding - - - ko:K08365,ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 DYD2_k127_5933180_64 504832.OCAR_7761 6.663e-15 83.0 COG2608@1|root,COG2608@2|Bacteria,1N9WI@1224|Proteobacteria,2UGVC@28211|Alphaproteobacteria,3K14W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Heavy-metal-associated domain - - - ko:K07213 ko04978,map04978 - - - ko00000,ko00001 - - - HMA DYD2_k127_5933180_25 1177928.TH2_19774 2.352e-75 259.0 COG4232@1|root,COG4232@2|Bacteria,1RG8V@1224|Proteobacteria,2U88V@28211|Alphaproteobacteria,2JVNI@204441|Rhodospirillales 204441|Rhodospirillales CO Cytochrome C biogenesis protein transmembrane region - - - - - - - - - - - - - DYD2_k127_5933180_13 443218.AS9A_4162 4.422e-124 411.0 COG3391@1|root,COG3391@2|Bacteria,2H8XQ@201174|Actinobacteria 201174|Actinobacteria S amine dehydrogenase activity - - - - - - - - - - - - - DYD2_k127_5933180_0 1207063.P24_18102 0.0 1092.0 COG2217@1|root,COG2217@2|Bacteria,1R5MM@1224|Proteobacteria,2TXNK@28211|Alphaproteobacteria,2JVG6@204441|Rhodospirillales 204441|Rhodospirillales P heavy metal translocating P-type ATPase - - - - - - - - - - - - E1-E2_ATPase,HMA,Hydrolase DYD2_k127_5933180_68 1292034.OR37_03709 1.672e-05 54.0 2F929@1|root,341DY@2|Bacteria,1N7EV@1224|Proteobacteria,2UINC@28211|Alphaproteobacteria,2KJB9@204458|Caulobacterales 204458|Caulobacterales - - - - - - - - - - - - - - - DYD2_k127_5933180_60 395494.Galf_1896 8.391e-31 126.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2VVBG@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - ko:K08365 - - - - ko00000,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 DYD2_k127_5933180_56 1132855.KB913035_gene1548 2.83e-35 138.0 COG2608@1|root,COG2608@2|Bacteria,1RDCB@1224|Proteobacteria,2VR3E@28216|Betaproteobacteria 28216|Betaproteobacteria P PFAM Mercuric transport protein MerT merT - - ko:K08363 - - - - ko00000,ko02000 1.A.72.1 - - MerT DYD2_k127_5933180_63 596154.Alide2_3379 6.412e-18 84.0 COG2608@1|root,COG2608@2|Bacteria,1N95B@1224|Proteobacteria,2VSRA@28216|Betaproteobacteria,4AF00@80864|Comamonadaceae 28216|Betaproteobacteria P Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein merP - - ko:K08364 - - - - ko00000,ko02000 1.A.72.1 - - HMA DYD2_k127_5933180_4 292415.Tbd_1341 4.873e-206 657.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KSPW@119069|Hydrogenophilales 119069|Hydrogenophilales C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.16.1.1 ko:K00520 - - - - ko00000,ko01000 - - - HMA,Pyr_redox_2,Pyr_redox_dim DYD2_k127_5933180_28 582744.Msip34_1326 1.555e-73 254.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,2VQ08@28216|Betaproteobacteria,2KN5N@206350|Nitrosomonadales 206350|Nitrosomonadales P PFAM cation efflux protein - - - - - - - - - - - - Cation_efflux DYD2_k127_5933180_53 1122603.ATVI01000007_gene1736 9.607e-42 157.0 COG1742@1|root,COG1742@2|Bacteria,1MZI8@1224|Proteobacteria,1SA4U@1236|Gammaproteobacteria,1X7SH@135614|Xanthomonadales 135614|Xanthomonadales S UPF0060 membrane protein - - - ko:K09771 - - - - ko00000,ko02000 2.A.7.26 - - UPF0060 DYD2_k127_5933180_54 472759.Nhal_1713 1.32e-37 148.0 COG3794@1|root,COG3794@2|Bacteria,1N0BX@1224|Proteobacteria,1SFAN@1236|Gammaproteobacteria,1X10X@135613|Chromatiales 135613|Chromatiales C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - - DYD2_k127_5933180_43 595494.Tola_1511 4.839e-55 200.0 COG2834@1|root,COG2834@2|Bacteria,1RFBN@1224|Proteobacteria,1S7A5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - DUF1571 DYD2_k127_5933180_37 748280.NH8B_2023 6.044e-64 222.0 COG3832@1|root,COG3832@2|Bacteria,1RICZ@1224|Proteobacteria,2VTB3@28216|Betaproteobacteria 28216|Betaproteobacteria S polyketide cyclase - - - - - - - - - - - - Polyketide_cyc,Polyketide_cyc2 DYD2_k127_5933180_51 1121939.L861_19140 7.59e-44 165.0 2DMWA@1|root,32U36@2|Bacteria,1N1CC@1224|Proteobacteria,1SRZE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5933180_33 1123368.AUIS01000001_gene1987 3.525e-68 237.0 COG0697@1|root,COG0697@2|Bacteria,1N3FA@1224|Proteobacteria,1RYMI@1236|Gammaproteobacteria,2NBY3@225057|Acidithiobacillales 225057|Acidithiobacillales EGP EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_5981081_6 1147.D082_34610 7.414e-26 107.0 COG0537@1|root,COG0537@2|Bacteria,1G6R2@1117|Cyanobacteria,1H5PV@1142|Synechocystis 1117|Cyanobacteria FG HIT domain hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT DYD2_k127_5981081_7 1211579.PP4_21500 5.589e-22 109.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1RSE0@1236|Gammaproteobacteria 1236|Gammaproteobacteria E 2-dehydrogenase iolG - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_5981081_5 1122134.KB893650_gene1428 2.602e-32 134.0 COG2128@1|root,COG2128@2|Bacteria,1PC51@1224|Proteobacteria,1RS2U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Carboxymuconolactone decarboxylase - - - - - - - - - - - - CMD DYD2_k127_5981081_4 1120983.KB894577_gene3580 1.117e-32 142.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - 1.13.11.4,4.1.2.17 ko:K00450,ko:K01628 ko00051,ko00350,ko01100,ko01120,map00051,map00350,map01100,map01120 - R02262,R02656 RC00603,RC00604,RC00764 ko00000,ko00001,ko01000 - - - Cupin_2,Lipase_GDSL_2 DYD2_k127_5981081_2 1120983.KB894577_gene3579 6.493e-123 399.0 COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2U6JP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase DYD2_k127_5981081_0 1120983.KB894577_gene3578 3.833e-164 523.0 COG0673@1|root,COG0673@2|Bacteria,1PGFP@1224|Proteobacteria,2V8DN@28211|Alphaproteobacteria,1JQA3@119043|Rhodobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_5981081_3 296591.Bpro_3022 2.639e-81 304.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VMVX@28216|Betaproteobacteria,4A9VB@80864|Comamonadaceae 28216|Betaproteobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_5981081_1 1411123.JQNH01000001_gene2072 1.469e-153 494.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria C L-carnitine dehydratase bile acid-inducible protein F MA20_43260 - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 DYD2_k127_6026878_41 1231391.AMZF01000007_gene1511 6.499e-41 165.0 COG0715@1|root,COG0715@2|Bacteria,1RCBF@1224|Proteobacteria,2VZS3@28216|Betaproteobacteria 28216|Betaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 DYD2_k127_6026878_6 1120983.KB894571_gene2468 7.864e-134 435.0 COG1073@1|root,COG1073@2|Bacteria,1PJHR@1224|Proteobacteria,2U2QB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S alpha beta - - - - - - - - - - - - - DYD2_k127_6026878_12 1280953.HOC_18489 3.663e-102 344.0 COG0604@1|root,COG0604@2|Bacteria,1MXRX@1224|Proteobacteria,2TRSQ@28211|Alphaproteobacteria,43YGQ@69657|Hyphomonadaceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_6026878_0 1380394.JADL01000002_gene1394 9.191e-195 616.0 COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria,2JT4J@204441|Rhodospirillales 204441|Rhodospirillales E Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 DYD2_k127_6026878_18 469383.Cwoe_1943 4.064e-94 320.0 COG1071@1|root,COG1071@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor - - 1.2.4.1,1.2.4.4 ko:K00161,ko:K11381,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD2_k127_6026878_2 991905.SL003B_1036 1.686e-163 525.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,4BQ15@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Transketolase, pyrimidine binding domain - - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD2_k127_6026878_7 1313172.YM304_29650 5.945e-113 384.0 COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia 84992|Acidimicrobiia C e3 binding domain - - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD2_k127_6026878_28 1187851.A33M_1620 5.063e-72 252.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2U25R@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD2_k127_6026878_8 1380394.JADL01000002_gene1393 3.217e-109 361.0 COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U2X9@28211|Alphaproteobacteria,2JTJW@204441|Rhodospirillales 204441|Rhodospirillales I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 DYD2_k127_6026878_21 1352941.M877_29410 1.423e-90 305.0 COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria 201174|Actinobacteria P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - AAA_assoc_C,ABC_tran DYD2_k127_6026878_33 351607.Acel_0889 5.439e-60 225.0 COG0715@1|root,COG0715@2|Bacteria,2IDBN@201174|Actinobacteria 201174|Actinobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 DYD2_k127_6026878_38 351607.Acel_0886 3.222e-53 198.0 COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria,4EW2R@85013|Frankiales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD2_k127_6026878_34 351607.Acel_0887 8.851e-59 213.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4EVVP@85013|Frankiales 201174|Actinobacteria P binding-protein-dependent transport systems inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 DYD2_k127_6026878_13 631454.N177_3086 2.515e-101 339.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,1JNPS@119043|Rhodobiaceae 28211|Alphaproteobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD2_k127_6026878_31 485913.Krac_9346 5.604e-67 242.0 COG1073@1|root,COG1073@2|Bacteria,2G95Q@200795|Chloroflexi 200795|Chloroflexi S alpha beta - - - - - - - - - - - - DUF1100 DYD2_k127_6026878_44 95619.PM1_0221345 9.511e-33 140.0 COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria 1224|Proteobacteria E ornithine cyclodeaminase - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD2_k127_6026878_16 318996.AXAZ01000032_gene3443 5.22e-97 330.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TU4F@28211|Alphaproteobacteria,3JQPK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C FMN-dependent dehydrogenase MA20_37755 - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FMN_dh DYD2_k127_6026878_23 397278.JOJN01000005_gene774 2.961e-86 299.0 COG0006@1|root,COG0006@2|Bacteria 2|Bacteria E proline dipeptidase activity - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 DYD2_k127_6026878_30 123899.JPQP01000017_gene2309 5.816e-70 254.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPJ4@28216|Betaproteobacteria,3T36P@506|Alcaligenaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6026878_40 1184267.A11Q_1050 9.59e-48 184.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2MTW3@213481|Bdellovibrionales,2WKTX@28221|Deltaproteobacteria 213481|Bdellovibrionales F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD2_k127_6026878_17 1123242.JH636435_gene2928 7.778e-95 317.0 COG1670@1|root,COG1670@2|Bacteria,2J1BC@203682|Planctomycetes 203682|Planctomycetes J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 DYD2_k127_6026878_46 694429.Pyrfu_1622 1.652e-22 109.0 COG0066@1|root,arCOG02230@2157|Archaea,2XQNZ@28889|Crenarchaeota 28889|Crenarchaeota E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD2_k127_6026878_20 391626.OAN307_c32140 1.614e-92 319.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TT8I@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Aconitase family (aconitate hydratase) - - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase DYD2_k127_6026878_15 713586.KB900536_gene377 1.068e-100 337.0 COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,1T1T1@1236|Gammaproteobacteria,1X2QZ@135613|Chromatiales 135613|Chromatiales EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_6026878_51 292415.Tbd_2356 0.0001326 51.0 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,2VTZ2@28216|Betaproteobacteria 28216|Betaproteobacteria S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti DYD2_k127_6026878_50 1123392.AQWL01000005_gene3093 9.79e-05 51.0 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,2VTZ2@28216|Betaproteobacteria,1KSWM@119069|Hydrogenophilales 119069|Hydrogenophilales S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti DYD2_k127_6026878_24 795666.MW7_2512 7.654e-81 277.0 COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2VNXU@28216|Betaproteobacteria,1K116@119060|Burkholderiaceae 28216|Betaproteobacteria IQ short-chain dehydrogenase - - - - - - - - - - - - adh_short,adh_short_C2 DYD2_k127_6026878_26 76114.ebA4458 1.858e-78 269.0 COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2VIQH@28216|Betaproteobacteria,2KXBN@206389|Rhodocyclales 206389|Rhodocyclales IQ KR domain - - - - - - - - - - - - adh_short DYD2_k127_6026878_25 207954.MED92_02031 1.187e-80 277.0 28RZD@1|root,2ZEBA@2|Bacteria,1RBEH@1224|Proteobacteria,1RP8T@1236|Gammaproteobacteria,1XIH6@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - DYD2_k127_6026878_4 1317122.ATO12_05390 1.91e-145 472.0 COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,1HWQ8@117743|Flavobacteriia,2YJ6T@290174|Aquimarina 976|Bacteroidetes E DegT/DnrJ/EryC1/StrS aminotransferase family ybdL - 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_6026878_42 859657.RPSI07_3204 2.53e-35 149.0 2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,2VR1F@28216|Betaproteobacteria,1K3XE@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6026878_14 522306.CAP2UW1_3204 9.819e-101 336.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria 28216|Betaproteobacteria S aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD2_k127_6026878_43 1380394.JADL01000013_gene700 5.057e-35 136.0 COG5507@1|root,COG5507@2|Bacteria,1RH3Q@1224|Proteobacteria,2U9SM@28211|Alphaproteobacteria,2JWSY@204441|Rhodospirillales 204441|Rhodospirillales S NIPSNAP - - - - - - - - - - - - NIPSNAP DYD2_k127_6026878_45 1205680.CAKO01000035_gene262 3.437e-30 127.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria 28211|Alphaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA DYD2_k127_6026878_3 709797.CSIRO_0007 1.887e-151 486.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,3K48V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA DYD2_k127_6026878_48 709797.CSIRO_0006 2.36e-18 89.0 2AF3S@1|root,3152G@2|Bacteria,1PV19@1224|Proteobacteria,2V4HP@28211|Alphaproteobacteria,3K5ND@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6026878_47 709797.CSIRO_0006 7.464e-19 88.0 2AF3S@1|root,3152G@2|Bacteria,1PV19@1224|Proteobacteria,2V4HP@28211|Alphaproteobacteria,3K5ND@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6026878_11 158500.BV97_03786 1.341e-102 342.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,2K0DM@204457|Sphingomonadales 28211|Alphaproteobacteria Q 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - - - - - - - - - - DUF2437,FAA_hydrolase DYD2_k127_6026878_19 1123229.AUBC01000005_gene606 9.756e-94 317.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria,3JSMG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family MA20_16265 - - - - - - - - - - - FAA_hydrolase DYD2_k127_6026878_22 1205680.CAKO01000038_gene1586 2.203e-87 301.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JRXA@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6026878_10 1205680.CAKO01000038_gene1586 9.707e-105 359.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JRXA@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6026878_49 1297570.MESS4_p40050 3.38e-09 64.0 29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VG4S@28211|Alphaproteobacteria,43MH9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD2_k127_6026878_1 196490.AUEZ01000017_gene3196 3.053e-169 545.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family MA20_23145 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_6026878_29 1207063.P24_12502 2.03e-71 258.0 COG2271@1|root,COG2271@2|Bacteria,1R8Q1@1224|Proteobacteria,2U16E@28211|Alphaproteobacteria,2JRZF@204441|Rhodospirillales 204441|Rhodospirillales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_6026878_9 1205680.CAKO01000037_gene1249 3.268e-106 351.0 COG2220@1|root,COG2220@2|Bacteria,1R5GU@1224|Proteobacteria,2V9I3@28211|Alphaproteobacteria,2JUKN@204441|Rhodospirillales 204441|Rhodospirillales S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 DYD2_k127_6026878_27 1244869.H261_01572 1.628e-73 275.0 COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,2VCDR@28211|Alphaproteobacteria,2JU96@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - - DYD2_k127_6026878_32 414684.RC1_1514 3.352e-60 234.0 COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales 204441|Rhodospirillales Q Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD2_k127_6026878_35 251221.35211574 2.518e-58 214.0 COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria 1117|Cyanobacteria J Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_25 DYD2_k127_6026878_36 414684.RC1_1514 1.196e-56 208.0 COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales 204441|Rhodospirillales Q Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD2_k127_6026878_37 251221.35211574 7.888e-55 203.0 COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria 1117|Cyanobacteria J Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_25 DYD2_k127_6026878_39 414684.RC1_1514 5.957e-52 203.0 COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales 204441|Rhodospirillales Q Histone methylation protein DOT1 - - - - - - - - - - - - Methyltransf_31 DYD2_k127_6026878_5 1173024.KI912148_gene4881 5.477e-141 464.0 COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1JHRW@1189|Stigonemataceae 1117|Cyanobacteria E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 DYD2_k127_6040174_21 1349767.GJA_3317 2.439e-11 73.0 COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,2VSGX@28216|Betaproteobacteria,476QV@75682|Oxalobacteraceae 28216|Betaproteobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl DYD2_k127_6040174_4 323848.Nmul_A0664 1.811e-170 549.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,371TQ@32003|Nitrosomonadales 28216|Betaproteobacteria M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 DYD2_k127_6040174_5 1266925.JHVX01000003_gene469 1.952e-152 491.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,3723X@32003|Nitrosomonadales 28216|Betaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom DYD2_k127_6040174_17 1348657.M622_07995 3.595e-63 226.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,2KW5H@206389|Rhodocyclales 206389|Rhodocyclales I Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 DYD2_k127_6040174_11 323848.Nmul_A0661 3.576e-112 368.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,3721N@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD2_k127_6040174_13 323848.Nmul_A0660 4.638e-81 273.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,3722X@32003|Nitrosomonadales 28216|Betaproteobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF DYD2_k127_6040174_10 582744.Msip34_1409 1.1e-120 392.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,2KKZ6@206350|Nitrosomonadales 206350|Nitrosomonadales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD2_k127_6040174_9 887898.HMPREF0551_0952 3.727e-122 398.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,1K0QT@119060|Burkholderiaceae 28216|Betaproteobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD2_k127_6040174_7 323848.Nmul_A0657 2.126e-124 404.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,371SG@32003|Nitrosomonadales 28216|Betaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 DYD2_k127_6040174_6 323848.Nmul_A2632 3.482e-135 435.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,371P4@32003|Nitrosomonadales 28216|Betaproteobacteria J Methionine aminopeptidase map GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD2_k127_6040174_1 1288494.EBAPG3_20510 6.514e-311 975.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,372Z4@32003|Nitrosomonadales 28216|Betaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 DYD2_k127_6040174_14 1122604.JONR01000010_gene3902 2.657e-80 270.0 COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,1S2DI@1236|Gammaproteobacteria,1XBZM@135614|Xanthomonadales 135614|Xanthomonadales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - - - - - - - - - - Pep_deformylase DYD2_k127_6040174_12 1163617.SCD_n01661 1.967e-109 360.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria 28216|Betaproteobacteria F Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage mtaP - 2.4.2.28 ko:K00772,ko:K03815 ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110 M00034 R01402,R02297 RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 DYD2_k127_6040174_16 153948.NAL212_2411 1.19e-63 222.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,3731Z@32003|Nitrosomonadales 28216|Betaproteobacteria F Phosphoribosyl transferase domain hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran DYD2_k127_6040174_18 519989.ECTPHS_12993 1.966e-61 213.0 COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,1SE6E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S DsrE/DsrF-like family - - - - - - - - - - - - DrsE,DrsE_2 DYD2_k127_6040174_8 1288494.EBAPG3_920 3.154e-123 400.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,37274@32003|Nitrosomonadales 28216|Betaproteobacteria M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD2_k127_6040174_2 1304883.KI912532_gene2616 4.695e-271 849.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,2KUWJ@206389|Rhodocyclales 206389|Rhodocyclales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 DYD2_k127_6040174_15 261292.Nit79A3_1796 1.89e-72 258.0 COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,372FG@32003|Nitrosomonadales 28216|Betaproteobacteria D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - - - - - - - - - - ZipA_C DYD2_k127_6040174_0 1163617.SCD_n01668 0.0 1084.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria 28216|Betaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge DYD2_k127_6040174_19 1163617.SCD_n01671 2.859e-61 213.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria 28216|Betaproteobacteria S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K06879,ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF,QueF_N DYD2_k127_6040174_3 323848.Nmul_A1850 2.352e-174 556.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,372II@32003|Nitrosomonadales 28216|Betaproteobacteria E PFAM aminotransferase, class I dapC - 2.6.1.17 ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_6040174_20 360910.BAV1421 8.436e-25 106.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,3T2TT@506|Alcaligenaceae 28216|Betaproteobacteria E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 DYD2_k127_6052222_5 859657.RPSI07_mp0725 2.665e-09 61.0 COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2VHZM@28216|Betaproteobacteria,1K2Z8@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N DYD2_k127_6052222_1 472175.EL18_02583 1.228e-105 352.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TT48@28211|Alphaproteobacteria,43R36@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U transport systems - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 DYD2_k127_6052222_7 344747.PM8797T_03214 0.0007477 48.0 COG1502@1|root,COG1502@2|Bacteria,2IYFI@203682|Planctomycetes 203682|Planctomycetes I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N DYD2_k127_6052222_6 396595.TK90_1404 7.521e-05 51.0 2DTY0@1|root,33N5R@2|Bacteria,1NJ3H@1224|Proteobacteria,1SUIA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4168) - - - - - - - - - - - - DUF4168 DYD2_k127_6052222_2 1163617.SCD_n00020 5.047e-94 327.0 COG0668@1|root,COG0668@2|Bacteria,1MW7V@1224|Proteobacteria,2VHE7@28216|Betaproteobacteria 28216|Betaproteobacteria M mechanosensitive ion channel - - - - - - - - - - - - MS_channel DYD2_k127_6052222_4 1232410.KI421426_gene1441 1.341e-30 126.0 COG3063@1|root,COG3063@2|Bacteria,1QZ5S@1224|Proteobacteria,42XK8@68525|delta/epsilon subdivisions,2WSKB@28221|Deltaproteobacteria,43V3K@69541|Desulfuromonadales 28221|Deltaproteobacteria NU Tetratricopeptide repeat - - - - - - - - - - - - - DYD2_k127_6052222_0 580332.Slit_1228 7.165e-269 848.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria 1224|Proteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365,ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H DYD2_k127_6052222_3 290315.Clim_1318 8.239e-57 203.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - - - - - - - - - - - FHA,Trypsin,Trypsin_2 DYD2_k127_6188762_8 1187851.A33M_3848 1.488e-18 87.0 COG2021@1|root,COG2021@2|Bacteria,1QVBR@1224|Proteobacteria,2TWEP@28211|Alphaproteobacteria 28211|Alphaproteobacteria E May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation rutD - - ko:K09023 ko00240,ko01100,map00240,map01100 - R09983 RC02769 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD2_k127_6188762_4 883078.HMPREF9695_04349 9.327e-54 191.0 COG0251@1|root,COG0251@2|Bacteria,1RD6W@1224|Proteobacteria,2U8MG@28211|Alphaproteobacteria,3K1Y9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Endoribonuclease L-PSP rutC - - ko:K09021 ko00240,ko01100,map00240,map01100 - R09982 RC02768 ko00000,ko00001 - - - Ribonuc_L-PSP DYD2_k127_6188762_6 1205680.CAKO01000040_gene1081 2.521e-32 135.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase DYD2_k127_6188762_3 266264.Rmet_5382 6.781e-69 246.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6188762_1 404589.Anae109_1579 6.213e-117 381.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales 28221|Deltaproteobacteria S Rhomboid family - - - - - - - - - - - - Rhomboid DYD2_k127_6188762_7 1304880.JAGB01000001_gene912 8.412e-19 99.0 COG1661@1|root,COG1661@2|Bacteria,1VJDC@1239|Firmicutes,25DY9@186801|Clostridia 186801|Clostridia S Domain of unknown function (DUF296) - - - ko:K06934 - - - - ko00000 - - - DUF296 DYD2_k127_6188762_5 1121405.dsmv_2310 2.128e-51 199.0 COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42U0W@68525|delta/epsilon subdivisions,2WQRX@28221|Deltaproteobacteria,2MPQV@213118|Desulfobacterales 28221|Deltaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_6188762_0 479433.Caci_3916 7.951e-147 484.0 COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria 201174|Actinobacteria EH Belongs to the TPP enzyme family - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_6188762_2 398578.Daci_0191 1.087e-70 253.0 COG3181@1|root,COG3181@2|Bacteria,1R61X@1224|Proteobacteria,2VKTX@28216|Betaproteobacteria,4AGCT@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6198222_2 196367.JNFG01000031_gene8767 9.355e-218 683.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1K1NF@119060|Burkholderiaceae 28216|Betaproteobacteria C aconitate hydratase - - - - - - - - - - - - Aconitase,Aconitase_C DYD2_k127_6198222_24 1184267.A11Q_1834 2.837e-61 222.0 COG0583@1|root,COG0583@2|Bacteria,1NEWE@1224|Proteobacteria,4321H@68525|delta/epsilon subdivisions,2MUCR@213481|Bdellovibrionales,2WWNG@28221|Deltaproteobacteria 213481|Bdellovibrionales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_6198222_0 1342299.Z947_120 3.527e-241 758.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Hydrolase CocE NonD family - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD2_k127_6198222_23 1121861.KB899914_gene2088 2.949e-64 232.0 COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2TT57@28211|Alphaproteobacteria 28211|Alphaproteobacteria S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_6198222_38 757424.Hsero_1459 9.102e-18 93.0 COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2VJ7W@28216|Betaproteobacteria,4744J@75682|Oxalobacteraceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - 5.3.3.7 ko:K22003 ko00660,map00660 - R02244 RC00668 ko00000,ko00001,ko01000 - - - SBP_bac_11 DYD2_k127_6198222_9 1205680.CAKO01000010_gene3839 8.33e-119 389.0 COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria,2TUAG@28211|Alphaproteobacteria,2JRY4@204441|Rhodospirillales 204441|Rhodospirillales EM Belongs to the DapA family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD2_k127_6198222_15 1207063.P24_13693 2.589e-97 326.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,2JS33@204441|Rhodospirillales 204441|Rhodospirillales S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_6198222_10 1380355.JNIJ01000004_gene2787 3.35e-111 366.0 COG2358@1|root,COG2358@2|Bacteria,1NRH6@1224|Proteobacteria,2TT34@28211|Alphaproteobacteria,3JTPF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD2_k127_6198222_16 375286.mma_0819 1.093e-96 332.0 COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2VNS2@28216|Betaproteobacteria,476I4@75682|Oxalobacteraceae 28216|Betaproteobacteria C NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 DYD2_k127_6198222_7 1207063.P24_09536 1.784e-136 443.0 COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria,2JR8N@204441|Rhodospirillales 204441|Rhodospirillales E Putative serine dehydratase domain - - - - - - - - - - - - Ala_racemase_N,D-ser_dehydrat DYD2_k127_6198222_22 375286.mma_0820 1.775e-64 226.0 COG1917@1|root,COG1917@2|Bacteria,1MYMN@1224|Proteobacteria 1224|Proteobacteria S AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2 DYD2_k127_6198222_27 1100720.ALKN01000035_gene868 5.203e-56 208.0 COG3473@1|root,COG3473@2|Bacteria,1N3F7@1224|Proteobacteria,2VX2N@28216|Betaproteobacteria,4AJ13@80864|Comamonadaceae 28216|Betaproteobacteria Q Catalyzes the conversion of maleate to fumarate - - 4.1.1.76,5.2.1.1 ko:K01799,ko:K06033 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD2_k127_6198222_28 375286.mma_0821 5.932e-49 179.0 COG3193@1|root,COG3193@2|Bacteria,1PP2J@1224|Proteobacteria,2WAB3@28216|Betaproteobacteria,478BZ@75682|Oxalobacteraceae 28216|Betaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading DYD2_k127_6198222_14 1123023.JIAI01000006_gene63 1.09e-98 342.0 COG1073@1|root,COG1073@2|Bacteria,2GK5B@201174|Actinobacteria,4E21E@85010|Pseudonocardiales 201174|Actinobacteria S Alpha/beta hydrolase of unknown function (DUF1100) - - - - - - - - - - - - DUF1100 DYD2_k127_6198222_37 1125973.JNLC01000011_gene582 5.883e-21 104.0 COG1917@1|root,COG1917@2|Bacteria,1MYMN@1224|Proteobacteria,2UR93@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2 DYD2_k127_6198222_33 1120956.JHZK01000002_gene1019 7.578e-31 134.0 COG1917@1|root,COG1917@2|Bacteria,1MYMN@1224|Proteobacteria,2UR93@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2 DYD2_k127_6198222_21 1120956.JHZK01000002_gene996 1.604e-72 253.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein dddQ - - ko:K11312 - - - - ko00000 - - - Cupin_2,DUF4437 DYD2_k127_6198222_5 1123060.JONP01000008_gene4648 2.048e-159 537.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the amidase family - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD2_k127_6198222_36 1043205.AFYF01000022_gene703 5.987e-26 119.0 COG3608@1|root,COG3608@2|Bacteria,2IC8T@201174|Actinobacteria,4FFHR@85021|Intrasporangiaceae 201174|Actinobacteria S Succinylglutamate desuccinylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA DYD2_k127_6198222_31 570952.ATVH01000014_gene1908 1.93e-38 155.0 COG0730@1|root,COG0730@2|Bacteria,1MWAN@1224|Proteobacteria,2TS4X@28211|Alphaproteobacteria,2JSQQ@204441|Rhodospirillales 204441|Rhodospirillales S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE DYD2_k127_6198222_29 56780.SYN_01562 3.56e-48 182.0 COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,42TNF@68525|delta/epsilon subdivisions,2WQ1R@28221|Deltaproteobacteria,2MRXW@213462|Syntrophobacterales 28221|Deltaproteobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - PEMT DYD2_k127_6198222_20 608538.HTH_0637 1.469e-72 267.0 COG0028@1|root,COG0028@2|Bacteria,2G3KM@200783|Aquificae 200783|Aquificae H TIGRFAM acetolactate synthase, large subunit, biosynthetic type ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_6198222_18 1380394.JADL01000021_gene1881 1.869e-79 271.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase DYD2_k127_6198222_35 1071679.BG57_17755 3.886e-28 123.0 COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VQD1@28216|Betaproteobacteria,1JZSD@119060|Burkholderiaceae 28216|Betaproteobacteria Q Carboxymethylenebutenolidase clcD - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD2_k127_6198222_25 1380394.JADL01000001_gene2940 1.176e-60 213.0 COG0066@1|root,COG0066@2|Bacteria,1RBRQ@1224|Proteobacteria,2UA0M@28211|Alphaproteobacteria,2JXDY@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the LeuD family - - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - - DYD2_k127_6198222_3 1380394.JADL01000001_gene2941 2.288e-178 568.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TT8I@28211|Alphaproteobacteria,2JV7M@204441|Rhodospirillales 204441|Rhodospirillales E Aconitase family (aconitate hydratase) - - - - - - - - - - - - Aconitase DYD2_k127_6198222_11 1380394.JADL01000001_gene2932 5.513e-107 358.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TUUN@28211|Alphaproteobacteria,2JWV8@204441|Rhodospirillales 204441|Rhodospirillales G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase DYD2_k127_6198222_17 1295642.H839_03851 1.647e-84 288.0 COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli,1WFNF@129337|Geobacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG_4 - 1.1.1.69 ko:K00046 - - - - ko00000,ko01000 - - - adh_short_C2 DYD2_k127_6198222_34 1163617.SCD_n00824 8.207e-31 139.0 COG0454@1|root,COG0454@2|Bacteria,1N1AI@1224|Proteobacteria 1224|Proteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 DYD2_k127_6198222_8 1120972.AUMH01000009_gene521 1.286e-122 405.0 COG1960@1|root,COG1960@2|Bacteria,1TR1Y@1239|Firmicutes,4HC1N@91061|Bacilli 91061|Bacilli I Acyl-CoA dehydrogenase, C-terminal domain - - - ko:K06446 ko00930,ko01100,ko01120,map00930,map01100,map01120 - R06943 RC00052 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_6198222_1 1097668.BYI23_C004550 1.547e-227 725.0 COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1K035@119060|Burkholderiaceae 28216|Betaproteobacteria C CoA-binding domain protein - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig DYD2_k127_6198222_6 1231391.AMZF01000069_gene2125 9.859e-155 499.0 COG2271@1|root,COG2271@2|Bacteria,1QTYR@1224|Proteobacteria 1224|Proteobacteria G Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_6198222_19 1123060.JONP01000024_gene2523 9.693e-73 258.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2U8QU@28211|Alphaproteobacteria,2JWYA@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6198222_12 314345.SPV1_05647 1.028e-105 347.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria 1224|Proteobacteria Q dienelactone hydrolase MA20_42490 - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD2_k127_6198222_13 113395.AXAI01000007_gene1460 2.901e-99 329.0 COG1011@1|root,COG1011@2|Bacteria,1NCRU@1224|Proteobacteria,2U167@28211|Alphaproteobacteria,3JXS9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 DYD2_k127_6198222_26 1163617.SCD_n02073 1.163e-56 203.0 2CCFR@1|root,2Z7VF@2|Bacteria,1MXHU@1224|Proteobacteria,2VHMR@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6198222_32 391735.Veis_2974 1.786e-35 140.0 COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,2VSYU@28216|Betaproteobacteria,4AEKB@80864|Comamonadaceae 28216|Betaproteobacteria S Carboxymuconolactone decarboxylase family pcaC - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - Abhydrolase_1,CMD DYD2_k127_6198222_4 1532557.JL37_19035 2.988e-167 542.0 COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria 28216|Betaproteobacteria EH Belongs to the TPP enzyme family - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_6212646_19 101510.RHA1_ro11181 9.83e-63 228.0 COG0447@1|root,COG0447@2|Bacteria,2HGHM@201174|Actinobacteria,4FZY1@85025|Nocardiaceae 201174|Actinobacteria H Enoyl-CoA hydratase/isomerase - - 4.1.3.36 ko:K01661,ko:K07536 ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220 M00116,M00540 R05592,R07263 RC01429,RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD2_k127_6212646_2 1125973.JNLC01000010_gene1411 1.302e-186 593.0 COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,3JQQG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - - - - - - - - - - Abhydrolase_6,DUF1100,Peptidase_S9 DYD2_k127_6212646_25 870187.Thini_2720 1.109e-34 137.0 COG3223@1|root,COG3223@2|Bacteria,1RD8R@1224|Proteobacteria,1S4FE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein PsiE homolog psiE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K13256 - - - - ko00000 - - - PsiE DYD2_k127_6212646_18 1110502.TMO_1176 9.588e-66 229.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,2JS2Q@204441|Rhodospirillales 204441|Rhodospirillales C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD2_k127_6212646_15 1089551.KE386572_gene4447 3.31e-90 305.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TRA8@28211|Alphaproteobacteria,4BPA8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM coxM - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD2_k127_6212646_1 690585.JNNU01000002_gene5329 4.149e-200 649.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4B7Q0@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_6212646_0 1144310.PMI07_000354 2.233e-209 677.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4B7Q0@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_6212646_7 1207063.P24_04649 2.309e-140 456.0 COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,2JQ5B@204441|Rhodospirillales 204441|Rhodospirillales E COG0626 Cystathionine beta-lyases cystathionine gamma-synthases metC - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP DYD2_k127_6212646_11 298653.Franean1_4518 1.183e-110 366.0 COG2084@1|root,COG2084@2|Bacteria 2|Bacteria I phosphogluconate dehydrogenase (decarboxylating) activity - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD2_k127_6212646_13 991905.SL003B_1106 9.402e-102 340.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,4BR5W@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - ADH_zinc_N,GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_6212646_5 1121861.KB899935_gene468 1.819e-156 506.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,2JQ3B@204441|Rhodospirillales 204441|Rhodospirillales ET general L-amino acid-binding periplasmic protein AapJ - - - ko:K09969 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 DYD2_k127_6212646_8 1238182.C882_2174 3.9e-140 456.0 COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2TR7G@28211|Alphaproteobacteria,2JQ13@204441|Rhodospirillales 204441|Rhodospirillales E acid transport system permease - - - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 DYD2_k127_6212646_6 1123060.JONP01000006_gene4804 3.5e-150 492.0 COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria,2JPI5@204441|Rhodospirillales 204441|Rhodospirillales E COG0765 ABC-type amino acid transport system, permease component - - - ko:K09971 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 DYD2_k127_6212646_10 1121861.KB899912_gene975 1.694e-113 388.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,2JPJB@204441|Rhodospirillales 204441|Rhodospirillales E acid transport - - - ko:K09972 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran DYD2_k127_6212646_9 1000565.METUNv1_03400 3.783e-121 401.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,2KVG7@206389|Rhodocyclales 206389|Rhodocyclales S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp DYD2_k127_6212646_12 1123393.KB891316_gene1511 2.579e-102 336.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,1KS0G@119069|Hydrogenophilales 119069|Hydrogenophilales F Queuosine biosynthesis protein QueC - - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC DYD2_k127_6212646_22 292415.Tbd_2204 1.272e-49 188.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,1KS8A@119069|Hydrogenophilales 119069|Hydrogenophilales D TolA binding protein trimerisation - - - - - - - - - - - - TPR_6,TolA_bind_tri DYD2_k127_6212646_20 1163617.SCD_n00677 2.513e-53 194.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD2_k127_6212646_3 1163617.SCD_n00676 6.417e-181 575.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria 28216|Betaproteobacteria U Involved in the tonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N DYD2_k127_6212646_23 1163617.SCD_n00675 7.351e-44 173.0 COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,2WGP5@28216|Betaproteobacteria 28216|Betaproteobacteria M Cell division and transport-associated protein TolA tolA - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 DYD2_k127_6212646_21 1163617.SCD_n00674 1.295e-50 183.0 COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria 28216|Betaproteobacteria U Pfam Biopolymer transport protein ExbD TolR tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD DYD2_k127_6212646_14 323848.Nmul_A2717 2.105e-98 326.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,371SV@32003|Nitrosomonadales 28216|Betaproteobacteria U MotA TolQ ExbB proton channel tolQ - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB DYD2_k127_6212646_24 1255043.TVNIR_3373 7.911e-39 149.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1WYUJ@135613|Chromatiales 135613|Chromatiales S Tol-Pal system-associated acyl-CoA thioesterase - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 DYD2_k127_6212646_4 261292.Nit79A3_0380 8.982e-178 563.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,37231@32003|Nitrosomonadales 28216|Betaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N DYD2_k127_6212646_16 1288494.EBAPG3_9150 1.478e-78 266.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,3724S@32003|Nitrosomonadales 28216|Betaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N DYD2_k127_6212646_17 580332.Slit_0512 4.7e-76 259.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,44VRQ@713636|Nitrosomonadales 28216|Betaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC DYD2_k127_6217778_1 1298867.AUES01000067_gene5125 1.096e-206 684.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1 DYD2_k127_6217778_3 710686.Mycsm_05706 3.433e-100 342.0 COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,23FDA@1762|Mycobacteriaceae 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg DYD2_k127_6217778_5 472759.Nhal_3549 1.042e-62 223.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1WYN6@135613|Chromatiales 135613|Chromatiales K SMART cyclic nucleotide-binding - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding DYD2_k127_6217778_4 1504672.669787430 2.911e-72 255.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJBE@28216|Betaproteobacteria,4ACD2@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6217778_0 323848.Nmul_A1109 4.515e-308 955.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,372VA@32003|Nitrosomonadales 28216|Betaproteobacteria O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 DYD2_k127_6217778_2 240292.Ava_3911 1.564e-148 483.0 COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1HJCQ@1161|Nostocales 1117|Cyanobacteria E PFAM Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 DYD2_k127_6237572_9 795666.MW7_3498 7.251e-97 319.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,1K44Q@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 DYD2_k127_6237572_7 1121033.AUCF01000019_gene3705 1.015e-99 336.0 COG0535@1|root,COG0535@2|Bacteria,1N5G8@1224|Proteobacteria,2VB0H@28211|Alphaproteobacteria,2JVSF@204441|Rhodospirillales 204441|Rhodospirillales S Iron-sulfur cluster-binding domain - - - - - - - - - - - - Radical_SAM,SPASM DYD2_k127_6237572_19 767434.Fraau_0124 5.412e-29 122.0 COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,1SFMR@1236|Gammaproteobacteria,1X7TA@135614|Xanthomonadales 135614|Xanthomonadales T Universal stress protein - - - - - - - - - - - - Usp DYD2_k127_6237572_13 420662.Mpe_A2471 8.844e-67 237.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,1KJZH@119065|unclassified Burkholderiales 28216|Betaproteobacteria K Regulator - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding DYD2_k127_6237572_23 1366050.N234_00560 4.947e-13 76.0 COG0745@1|root,COG0745@2|Bacteria,1NGK9@1224|Proteobacteria,2VY2G@28216|Betaproteobacteria 28216|Betaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD2_k127_6237572_12 296591.Bpro_1167 2.247e-77 265.0 COG2197@1|root,COG2197@2|Bacteria,1RENN@1224|Proteobacteria,2VR4J@28216|Betaproteobacteria,4AETN@80864|Comamonadaceae 28216|Betaproteobacteria K Bacterial regulatory proteins, luxR family - - - - - - - - - - - - GerE,Response_reg DYD2_k127_6237572_8 1158292.JPOE01000002_gene3435 6.251e-99 353.0 COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2WEET@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,dCache_1 DYD2_k127_6237572_2 504832.OCAR_4862 2.707e-243 765.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,3JU1V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Function proposed based on presence of conserved amino acid motif, structural feature or limited homology phbC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - PHBC_N,PhaC_N DYD2_k127_6237572_4 748247.AZKH_0533 1.86e-164 529.0 COG0657@1|root,COG0657@2|Bacteria,1MV89@1224|Proteobacteria,2VJJC@28216|Betaproteobacteria,2M03F@206389|Rhodocyclales 206389|Rhodocyclales I Ethylbenzene dehydrogenase - - - - - - - - - - - - EB_dh DYD2_k127_6237572_21 391612.CY0110_13256 1.579e-20 97.0 COG5622@1|root,COG5622@2|Bacteria,1G656@1117|Cyanobacteria,3KHVD@43988|Cyanothece 1117|Cyanobacteria N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach DYD2_k127_6237572_18 1123393.KB891326_gene80 6.38e-31 124.0 COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,1KSAT@119069|Hydrogenophilales 119069|Hydrogenophilales J 'Cold-shock' DNA-binding domain - - - - - - - - - - - - CSD,Ribosomal_S30AE DYD2_k127_6237572_16 697282.Mettu_0374 1.437e-45 170.0 COG0517@1|root,COG0517@2|Bacteria,1QJRF@1224|Proteobacteria,1THSQ@1236|Gammaproteobacteria,1XFJQ@135618|Methylococcales 135618|Methylococcales S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD2_k127_6237572_22 296591.Bpro_0926 5.807e-16 81.0 COG4876@1|root,COG4876@2|Bacteria,1NJCS@1224|Proteobacteria,2VYBB@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6237572_5 118166.JH976537_gene972 4.47e-150 481.0 COG1335@1|root,COG1335@2|Bacteria,1G10P@1117|Cyanobacteria,1H8R3@1150|Oscillatoriales 1117|Cyanobacteria Q isochorismatase - - - - - - - - - - - - - DYD2_k127_6237572_1 1123368.AUIS01000029_gene1288 1.693e-246 768.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the RtcB family rtcB - 6.5.1.3 ko:K14415,ko:K18148 ko01501,map01501 - - - ko00000,ko00001,ko01000,ko03016 - - - RtcB DYD2_k127_6237572_15 1123368.AUIS01000029_gene1287 1.343e-47 174.0 COG1371@1|root,COG1371@2|Bacteria,1N301@1224|Proteobacteria,1T17H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease DYD2_k127_6237572_0 243233.MCA1213 2.306e-256 801.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,1SZW9@1236|Gammaproteobacteria,1XFPE@135618|Methylococcales 135618|Methylococcales L DNA polymerase X family - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP DYD2_k127_6237572_6 1163617.SCD_n01945 3.032e-147 484.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria 28216|Betaproteobacteria S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH DYD2_k127_6237572_3 671143.DAMO_1019 1.745e-171 548.0 COG1488@1|root,COG1488@2|Bacteria,2NNUE@2323|unclassified Bacteria 2|Bacteria H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase DYD2_k127_6237572_20 1123368.AUIS01000008_gene2140 9.1e-27 117.0 COG3945@1|root,COG3945@2|Bacteria,1N0BD@1224|Proteobacteria,1SG9J@1236|Gammaproteobacteria,2NDD3@225057|Acidithiobacillales 225057|Acidithiobacillales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin DYD2_k127_6237572_17 748247.AZKH_3207 4.352e-31 126.0 COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,2KWZ1@206389|Rhodocyclales 206389|Rhodocyclales S Invasion gene expression up-regulator SirB sirB - - - - - - - - - - - SirB DYD2_k127_6237572_11 640081.Dsui_1460 1.838e-82 280.0 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,2KVHP@206389|Rhodocyclales 206389|Rhodocyclales K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding DYD2_k127_6237572_14 265072.Mfla_0111 2.899e-54 197.0 COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,2VS72@28216|Betaproteobacteria,2KMVW@206350|Nitrosomonadales 206350|Nitrosomonadales J Domain of unknown function (DUF4202) - - - - - - - - - - - - DUF4202 DYD2_k127_6237572_10 292415.Tbd_0070 7.375e-86 286.0 COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,2VIU7@28216|Betaproteobacteria,1KSV4@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome D1 heme domain - - - - - - - - - - - - Cytochrom_D1,Cytochrome_CBB3 DYD2_k127_6238501_7 557598.LHK_00165 3.276e-110 360.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KQ47@206351|Neisseriales 206351|Neisseriales T Transcriptional regulatory protein, C terminal phoB - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD2_k127_6238501_14 1288494.EBAPG3_2480 1.732e-60 211.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,3734V@32003|Nitrosomonadales 28216|Betaproteobacteria S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 DYD2_k127_6238501_9 522306.CAP2UW1_4348 1.471e-106 351.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,1KQ7U@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran DYD2_k127_6238501_17 1266925.JHVX01000004_gene1182 8.903e-41 158.0 COG3165@1|root,COG3165@2|Bacteria,1N314@1224|Proteobacteria,2VU2B@28216|Betaproteobacteria,3730H@32003|Nitrosomonadales 28216|Betaproteobacteria S protein conserved in bacteria - - - ko:K03690 - - - - ko00000 - - - SCP2 DYD2_k127_6238501_8 1232437.KL662047_gene5143 6.395e-109 383.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,42MVH@68525|delta/epsilon subdivisions,2WMHB@28221|Deltaproteobacteria,2MME3@213118|Desulfobacterales 28221|Deltaproteobacteria HJ Sugar-transfer associated ATP-grasp - - - - - - - - - - - - ATPgrasp_ST DYD2_k127_6238501_5 519989.ECTPHS_04009 3.813e-123 415.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales 135613|Chromatiales E 7 transmembrane helices usually fused to an inactive transglutaminase - - - - - - - - - - - - 7TM_transglut,Transglut_i_TM DYD2_k127_6238501_19 396588.Tgr7_2935 2.174e-33 136.0 COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SARP@1236|Gammaproteobacteria 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease DYD2_k127_6238501_0 1266925.JHVX01000004_gene1183 1.143e-226 711.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,3723G@32003|Nitrosomonadales 28216|Betaproteobacteria H Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 DYD2_k127_6238501_1 859657.RPSI07_2905 2.6e-188 601.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,1K5EX@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K14392 - - - - ko00000,ko02000 2.A.21.1 - - SSF DYD2_k127_6238501_6 765910.MARPU_12890 2.673e-110 364.0 COG0608@1|root,COG0608@2|Bacteria,1N37P@1224|Proteobacteria,1RQTR@1236|Gammaproteobacteria,1WWFV@135613|Chromatiales 135613|Chromatiales L single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - - - - - - - - - - - DYD2_k127_6238501_15 1304883.KI912532_gene873 6.222e-56 211.0 COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,2KW9S@206389|Rhodocyclales 206389|Rhodocyclales S VanZ like family - - - - - - - - - - - - VanZ DYD2_k127_6238501_18 85643.Tmz1t_1669 1.638e-35 139.0 COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,2KX0C@206389|Rhodocyclales 206389|Rhodocyclales S MazG-like family - - - - - - - - - - - - MazG-like DYD2_k127_6238501_16 1000565.METUNv1_03656 2.121e-49 179.0 COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,2KWNM@206389|Rhodocyclales 206389|Rhodocyclales C ferredoxin - - - - - - - - - - - - 2Fe-2S_thioredx DYD2_k127_6238501_13 1163617.SCD_n00158 2.655e-67 235.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria 28216|Betaproteobacteria S hydrolase of the alpha beta superfamily - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4,Peptidase_S15 DYD2_k127_6238501_4 1163617.SCD_n00157 3.537e-137 441.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria 28216|Betaproteobacteria P Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system nodI - - ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC_tran DYD2_k127_6238501_10 640081.Dsui_0720 3.712e-103 341.0 COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,2KVIE@206389|Rhodocyclales 206389|Rhodocyclales V ABC-2 type transporter nodJ - - ko:K09694 ko02010,map02010 M00252 - - ko00000,ko00001,ko00002,ko02000 3.A.1.102 - - ABC2_membrane DYD2_k127_6238501_12 1266925.JHVX01000003_gene430 2.246e-69 237.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,3737C@32003|Nitrosomonadales 28216|Betaproteobacteria S Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 DYD2_k127_6238501_11 1380394.JADL01000012_gene895 1.417e-85 291.0 COG0179@1|root,COG0179@2|Bacteria,1NM05@1224|Proteobacteria,2U0IB@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Domain of unknown function (DUF2437) - - - - - - - - - - - - DUF2437,FAA_hydrolase DYD2_k127_6238501_3 1163617.SCD_n00155 2.994e-145 470.0 COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria 28216|Betaproteobacteria L Belongs to the methyltransferase superfamily rlmL - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 DYD2_k127_6238501_2 596153.Alide_2607 6.044e-164 530.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,4AB40@80864|Comamonadaceae 28216|Betaproteobacteria S DinB superfamily egtB - - - - - - - - - - - DinB_2,FGE-sulfatase DYD2_k127_6238501_22 1177179.A11A3_14602 5.688e-09 62.0 2EGR5@1|root,33AHA@2|Bacteria,1NH3C@1224|Proteobacteria,1SIE7@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6298392_7 258052.JNYV01000002_gene1095 6.308e-14 79.0 COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,2M0QT@2063|Kitasatospora 201174|Actinobacteria S Zinc-binding dehydrogenase - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD2_k127_6298392_2 667632.KB890195_gene3478 6.588e-76 273.0 COG2513@1|root,COG2513@2|Bacteria,1PISN@1224|Proteobacteria,2W9Z1@28216|Betaproteobacteria,1KDWF@119060|Burkholderiaceae 28216|Betaproteobacteria G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase DYD2_k127_6298392_1 1509405.GV67_12565 3.274e-140 455.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,4B8SA@82115|Rhizobiaceae 28211|Alphaproteobacteria C L-lactate dehydrogenase lldD2 - 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 - R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh DYD2_k127_6298392_0 1209989.TepiRe1_0900 1.612e-147 481.0 COG0863@1|root,COG0863@2|Bacteria 2|Bacteria L N-4 methylation of cytosine - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase DYD2_k127_6298392_6 1318628.MARLIPOL_16289 3.181e-21 99.0 2F7U0@1|root,34084@2|Bacteria,1NZJ4@1224|Proteobacteria 1318628.MARLIPOL_16289|- - - - - - - - - - - - - - - - DYD2_k127_6298392_3 1318628.MARLIPOL_02715 3.192e-43 166.0 2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,1SUQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6298392_4 1157708.KB907467_gene526 5.263e-42 162.0 COG0346@1|root,COG0346@2|Bacteria,1RDVE@1224|Proteobacteria,2VREX@28216|Betaproteobacteria,4AJID@80864|Comamonadaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD2_k127_6298392_5 153948.NAL212_2158 6.707e-41 152.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,371T8@32003|Nitrosomonadales 28216|Betaproteobacteria C 4Fe-4S double cluster binding domain glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7,Fer4_8 DYD2_k127_6316829_0 1485544.JQKP01000002_gene1357 1.899e-126 417.0 COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,2WGMC@28216|Betaproteobacteria,44V6B@713636|Nitrosomonadales 28216|Betaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD2_k127_6316829_6 1288494.EBAPG3_10920 3.059e-17 83.0 2EG8X@1|root,33A0Q@2|Bacteria,1NMVN@1224|Proteobacteria,2VY0V@28216|Betaproteobacteria,373M2@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6316829_3 1163617.SCD_n02858 2.507e-37 146.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria 28216|Betaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA DYD2_k127_6316829_2 292415.Tbd_2674 1.098e-55 199.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria 28216|Betaproteobacteria S EVE domain - - - - - - - - - - - - EVE DYD2_k127_6316829_1 1472716.KBK24_0102910 2.167e-95 322.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2VV9X@28216|Betaproteobacteria,1K8N9@119060|Burkholderiaceae 28216|Betaproteobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD2_k127_6316829_5 1219035.NT2_02_05190 6.56e-22 104.0 COG1335@1|root,COG1335@2|Bacteria,1QK2B@1224|Proteobacteria,2U5X9@28211|Alphaproteobacteria,2K43F@204457|Sphingomonadales 204457|Sphingomonadales Q Isochorismatase family - - - - - - - - - - - - Isochorismatase DYD2_k127_6316829_4 795666.MW7_0585 8.488e-25 108.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6336_4 1198452.Jab_2c17710 1.046e-18 91.0 COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,2VSGX@28216|Betaproteobacteria,476QV@75682|Oxalobacteraceae 28216|Betaproteobacteria T Forkhead associated domain - - - - - - - - - - - - FHA,Yop-YscD_cpl DYD2_k127_6336_2 1278073.MYSTI_03911 6.894e-81 287.0 COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria 1224|Proteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 DYD2_k127_6336_3 1038859.AXAU01000003_gene5872 1.624e-67 238.0 COG1028@1|root,COG1028@2|Bacteria,1R3U8@1224|Proteobacteria,2U1SI@28211|Alphaproteobacteria,3JXX5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 DYD2_k127_6336_1 1123504.JQKD01000008_gene5334 3.425e-83 290.0 COG3181@1|root,COG3181@2|Bacteria,1RBX4@1224|Proteobacteria,2VQ66@28216|Betaproteobacteria,4AGJ9@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6336_0 1532558.JL39_17070 8.127e-195 631.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4B7Q0@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_6392867_6 713587.THITH_10185 3.809e-09 62.0 COG4795@1|root,COG4795@2|Bacteria,1MYPS@1224|Proteobacteria,1SHGQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria U general secretion pathway protein xpsJ - - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl DYD2_k127_6392867_4 1163617.SCD_n00396 8.413e-71 245.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria 28216|Betaproteobacteria M transglycosylase slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L DYD2_k127_6392867_3 1288494.EBAPG3_27700 2.712e-93 316.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,372R5@32003|Nitrosomonadales 28216|Betaproteobacteria GM NmrA-like family - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 DYD2_k127_6392867_1 1163617.SCD_n00398 3.727e-117 387.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria 28216|Betaproteobacteria J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd DYD2_k127_6392867_2 1411123.JQNH01000001_gene964 3.599e-98 324.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the GST superfamily MA20_22025 - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N,GST_N_3 DYD2_k127_6392867_5 1502851.FG93_00944 6.872e-14 76.0 2E46N@1|root,32Z2M@2|Bacteria,1N6SH@1224|Proteobacteria,2UHDJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6392867_0 266265.Bxe_B1517 3.387e-120 390.0 COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,1K5EP@119060|Burkholderiaceae 28216|Betaproteobacteria G Glycosyl hydrolase 36 superfamily, catalytic domain - - - ko:K13688 - - - - ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase DYD2_k127_6438276_1 266265.Bxe_B0283 1.469e-92 309.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2W8ET@28216|Betaproteobacteria,1KCUI@119060|Burkholderiaceae 28216|Betaproteobacteria C FAD binding domain - - - ko:K13796 - - - - ko00000 - - - FAD_binding_2 DYD2_k127_6438276_0 443598.AUFA01000002_gene2461 5.025e-139 449.0 COG2220@1|root,COG2220@2|Bacteria,1R5GU@1224|Proteobacteria 1224|Proteobacteria S Zn-dependent hydrolases of the beta-lactamase fold - - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 DYD2_k127_6438276_2 1231391.AMZF01000094_gene118 8.355e-74 262.0 COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria 28216|Betaproteobacteria EGP major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_6438276_3 472759.Nhal_3007 2.952e-50 184.0 COG0758@1|root,COG0758@2|Bacteria,1MZGB@1224|Proteobacteria,1S95S@1236|Gammaproteobacteria,1WYBS@135613|Chromatiales 135613|Chromatiales LU Putative molybdenum carrier - - - - - - - - - - - - MoCo_carrier DYD2_k127_6438276_4 1268622.AVS7_02147 1.78e-40 156.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VM6J@28216|Betaproteobacteria 28216|Betaproteobacteria C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid - - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh DYD2_k127_6450845_1 1163617.SCD_n00049 4.598e-317 986.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria 28216|Betaproteobacteria L Helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD2_k127_6450845_0 391038.Bphy_2588 0.0 1212.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,1K2G2@119060|Burkholderiaceae 28216|Betaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 DYD2_k127_6450845_7 1288494.EBAPG3_5100 1.105e-41 160.0 COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,3738A@32003|Nitrosomonadales 28216|Betaproteobacteria M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE DYD2_k127_6450845_4 1485544.JQKP01000002_gene1455 3.26e-111 371.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,44VB7@713636|Nitrosomonadales 28216|Betaproteobacteria L TIGRFAM DNA polymerase III, delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta DYD2_k127_6450845_3 1163617.SCD_n00056 2.14e-199 628.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria 28216|Betaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_6450845_2 1131553.JIBI01000015_gene643 1.906e-259 812.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,372TA@32003|Nitrosomonadales 28216|Betaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation lpdA GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim DYD2_k127_6450845_5 580332.Slit_0323 6.155e-87 308.0 2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6450845_6 1038858.AXBA01000011_gene1508 1.652e-82 282.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2TTDW@28211|Alphaproteobacteria,3EYBD@335928|Xanthobacteraceae 28211|Alphaproteobacteria C C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c that then channels them into the respiratory electron transport chain. Some electrons may be used for reductive CO(2) fixation - - - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - DYD2_k127_6450845_9 1126627.BAWE01000004_gene2878 2.597e-26 111.0 COG5501@1|root,COG5501@2|Bacteria,1N03V@1224|Proteobacteria,2TWQY@28211|Alphaproteobacteria,3JZTG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Sulphur oxidation protein SoxZ MA20_17515 - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ DYD2_k127_6450845_8 1125973.JNLC01000018_gene2101 1.081e-39 152.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2U72E@28211|Alphaproteobacteria,3JUV9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Sulfur oxidation protein SoxY MA20_17510 - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY DYD2_k127_6482974_1 1209984.BN978_01684 1.482e-78 274.0 COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,236EK@1762|Mycobacteriaceae 201174|Actinobacteria I PFAM NAD binding domain of 6-phosphogluconate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD2_k127_6482974_2 1158762.KB898037_gene2205 4.971e-44 165.0 COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,1SJ46@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 DYD2_k127_6482974_0 1095769.CAHF01000010_gene1222 3.556e-81 276.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,47249@75682|Oxalobacteraceae 28216|Betaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD2_k127_6495596_3 1288494.EBAPG3_6730 8.323e-206 648.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria,371M5@32003|Nitrosomonadales 28216|Betaproteobacteria C FAD linked oxidases, C-terminal domain glcD - 1.1.2.4,1.1.3.15,1.1.5.12 ko:K00102,ko:K00104,ko:K03777 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 - R00197,R00475,R00704,R11591 RC00042,RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 DYD2_k127_6495596_8 1095769.CAHF01000022_gene362 4.934e-145 464.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,4733C@75682|Oxalobacteraceae 28216|Betaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase glxR - 1.1.1.60 ko:K00042 ko00630,ko01100,map00630,map01100 - R01745,R01747 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD2_k127_6495596_2 1411123.JQNH01000001_gene2713 5.292e-233 737.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transport system fused permease components - - - - - - - - - - - - DUF3394,DctM DYD2_k127_6495596_11 331869.BAL199_20350 2.912e-104 367.0 COG2358@1|root,COG2358@2|Bacteria,1NSZ5@1224|Proteobacteria,2U3NZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transport system periplasmic component - - - ko:K07080 - - - - ko00000 - - - NMT1_3 DYD2_k127_6495596_10 390235.PputW619_3623 4.026e-125 406.0 COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,1RQF9@1236|Gammaproteobacteria,1YVIN@136845|Pseudomonas putida group 1236|Gammaproteobacteria G Belongs to the hyi family hyi GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0008903,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019752,GO:0032787,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044281,GO:0046487,GO:0046983,GO:0071704 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - iECO103_1326.ECO103_0481,iECO111_1330.ECO111_0541,iECO26_1355.ECO26_0541 AP_endonuc_2 DYD2_k127_6495596_15 1123392.AQWL01000010_gene2306 6.615e-48 178.0 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VSIN@28216|Betaproteobacteria,1KRTP@119069|Hydrogenophilales 119069|Hydrogenophilales S MobA-like NTP transferase domain - - - - - - - - - - - - NTP_transf_3 DYD2_k127_6495596_7 757424.Hsero_1612 2.871e-146 466.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2VH9H@28216|Betaproteobacteria,473K5@75682|Oxalobacteraceae 28216|Betaproteobacteria O AAA domain (Cdc48 subfamily) - - - - - - - - - - - - AAA,AAA_5 DYD2_k127_6495596_5 1121033.AUCF01000006_gene4262 1.129e-181 577.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2JQTH@204441|Rhodospirillales 204441|Rhodospirillales S protein conserved in bacteria - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE DYD2_k127_6495596_14 1125973.JNLC01000012_gene964 2.222e-49 184.0 COG5446@1|root,COG5446@2|Bacteria,1RBWQ@1224|Proteobacteria,2U9NN@28211|Alphaproteobacteria,3JTIZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Probable cobalt transporter subunit (CbtA) cbtA - - - - - - - - - - - CbtA DYD2_k127_6495596_17 1320556.AVBP01000001_gene4174 3.478e-07 55.0 2EKSU@1|root,33EGJ@2|Bacteria,1NGQH@1224|Proteobacteria,2UJHI@28211|Alphaproteobacteria,43MB9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Cobalt transporter subunit CbtB cbtB - - - - - - - - - - - CbtB DYD2_k127_6495596_6 1415778.JQMM01000001_gene777 1.197e-173 573.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1J53P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp DYD2_k127_6495596_16 1121033.AUCF01000013_gene1686 2.943e-35 143.0 COG0454@1|root,COG0456@2|Bacteria,1QUS0@1224|Proteobacteria,2TXDS@28211|Alphaproteobacteria,2JTYI@204441|Rhodospirillales 204441|Rhodospirillales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD2_k127_6495596_13 768710.DesyoDRAFT_3702 2.941e-53 190.0 COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia 186801|Clostridia S THIoesterase - - 3.1.2.29 ko:K18700 - - - - ko00000,ko01000 - - - 4HBT DYD2_k127_6495596_12 99598.Cal7507_5132 1.608e-103 344.0 COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1G3BJ@1117|Cyanobacteria,1HP35@1161|Nostocales 1117|Cyanobacteria L methylated-DNA- protein -cysteine S-methyltransferase - - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N DYD2_k127_6495596_1 640081.Dsui_2996 3.699e-257 805.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KV9Y@206389|Rhodocyclales 206389|Rhodocyclales NU Type II secretion system (T2SS), protein E, N-terminal domain - - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N DYD2_k127_6495596_4 1454004.AW11_01300 1.666e-183 586.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria 28216|Betaproteobacteria C PFAM Thiamine pyrophosphate - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C DYD2_k127_6495596_0 1380394.JADL01000003_gene4831 2.299e-310 959.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2JSY5@204441|Rhodospirillales 204441|Rhodospirillales C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR,POR_N DYD2_k127_6495596_9 1123073.KB899242_gene1461 2.019e-137 439.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1XA61@135614|Xanthomonadales 135614|Xanthomonadales CE Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2 DYD2_k127_6508583_13 1131553.JIBI01000011_gene721 5.33e-08 54.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,3732R@32003|Nitrosomonadales 28216|Betaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone DYD2_k127_6508583_2 159087.Daro_0605 3.904e-156 499.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,2KUY4@206389|Rhodocyclales 206389|Rhodocyclales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 DYD2_k127_6508583_8 292415.Tbd_2189 8.835e-63 224.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,1KSH3@119069|Hydrogenophilales 119069|Hydrogenophilales H Lumazine binding domain - - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding DYD2_k127_6508583_3 1266925.JHVX01000008_gene358 3.882e-152 488.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,371M0@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 DYD2_k127_6508583_7 1266925.JHVX01000008_gene357 2.967e-67 231.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2VQGE@28216|Betaproteobacteria,372ZT@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase DYD2_k127_6508583_12 1441629.PCH70_45200 8.571e-35 137.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1Z6QS@136849|Pseudomonas syringae group 1236|Gammaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB DYD2_k127_6508583_5 292415.Tbd_2193 5.496e-97 326.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,1KRKQ@119069|Hydrogenophilales 119069|Hydrogenophilales H AIR synthase related protein, N-terminal domain - - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD2_k127_6508583_9 1266925.JHVX01000008_gene354 5.44e-60 211.0 COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,3734R@32003|Nitrosomonadales 28216|Betaproteobacteria I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) pgpA - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA DYD2_k127_6508583_10 1163617.SCD_n00847 2.608e-59 211.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria 28216|Betaproteobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA DYD2_k127_6508583_6 216591.BCAM0940A 1.287e-73 253.0 COG0220@1|root,COG0220@2|Bacteria,1QTX5@1224|Proteobacteria,2VZVN@28216|Betaproteobacteria,1KFMI@119060|Burkholderiaceae 28216|Betaproteobacteria J Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 DYD2_k127_6508583_4 1432050.IE4771_CH02566 1.24e-126 411.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,4B96F@82115|Rhizobiaceae 28211|Alphaproteobacteria I Dehydrogenase MA20_25935 - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD2_k127_6508583_1 1288494.EBAPG3_7780 4.577e-178 563.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,371W0@32003|Nitrosomonadales 28216|Betaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD2_k127_6508583_11 1288494.EBAPG3_7770 5.923e-37 144.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,3739X@32003|Nitrosomonadales 28216|Betaproteobacteria S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX DYD2_k127_6508583_0 1095769.CAHF01000006_gene1959 4.835e-228 719.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,47292@75682|Oxalobacteraceae 28216|Betaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD2_k127_6542490_3 1163617.SCD_n01627 1.391e-314 980.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria 28216|Betaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA DYD2_k127_6542490_77 1163617.SCD_n01626 3.104e-46 172.0 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria 28216|Betaproteobacteria M Belongs to the skp family ompH - - ko:K06142 - - - - ko00000 - - - OmpH DYD2_k127_6542490_34 580332.Slit_1641 3.391e-117 392.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,44V3V@713636|Nitrosomonadales 28216|Betaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD DYD2_k127_6542490_72 1163617.SCD_n01624 1.08e-61 216.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria 28216|Betaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA DYD2_k127_6542490_40 1163617.SCD_n01623 4.286e-107 364.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria 28216|Betaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep DYD2_k127_6542490_28 1163617.SCD_n01622 1.315e-135 443.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria 28216|Betaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB DYD2_k127_6542490_67 1304883.KI912532_gene2594 1.089e-68 240.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,2KW1V@206389|Rhodocyclales 206389|Rhodocyclales L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII DYD2_k127_6542490_81 264198.Reut_A2220 1.252e-37 149.0 COG5615@1|root,COG5615@2|Bacteria,1N3BK@1224|Proteobacteria,2VQHM@28216|Betaproteobacteria,1K6ZQ@119060|Burkholderiaceae 28216|Betaproteobacteria S Copper resistance protein D - - - - - - - - - - - - CopD DYD2_k127_6542490_71 1163617.SCD_n01614 1.284e-65 242.0 COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,2WGF7@28216|Betaproteobacteria 28216|Betaproteobacteria J methyltransferase - - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase DYD2_k127_6542490_39 1288494.EBAPG3_13970 5.94e-108 357.0 COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,372Z7@32003|Nitrosomonadales 28216|Betaproteobacteria F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation ydiA - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase DYD2_k127_6542490_4 1163617.SCD_n01612 1.4e-289 899.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase DYD2_k127_6542490_26 1163617.SCD_n01611 4.287e-139 448.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria 28216|Betaproteobacteria M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 DYD2_k127_6542490_9 1005048.CFU_1252 3.735e-220 689.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,472ZF@75682|Oxalobacteraceae 28216|Betaproteobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N DYD2_k127_6542490_90 1266925.JHVX01000001_gene2509 4.573e-27 115.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,373MD@32003|Nitrosomonadales 28216|Betaproteobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC DYD2_k127_6542490_47 1392838.AWNM01000039_gene830 1.649e-97 326.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,3T390@506|Alcaligenaceae 28216|Betaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C DYD2_k127_6542490_0 323848.Nmul_A1150 0.0 1590.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PV5D@1224|Proteobacteria,2WB3J@28216|Betaproteobacteria,37281@32003|Nitrosomonadales 28216|Betaproteobacteria CEH PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 DYD2_k127_6542490_11 1487953.JMKF01000022_gene2509 3.181e-205 647.0 COG0161@1|root,COG0161@2|Bacteria,1G1QE@1117|Cyanobacteria,1H9SQ@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family bioA - 2.6.1.18,2.6.1.62 ko:K00822,ko:K00833 ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100 M00123,M00573,M00577 R00907,R03231,R04187 RC00006,RC00008,RC00062,RC00160,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_6542490_31 257310.BB2486 1.048e-123 403.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2VJQR@28216|Betaproteobacteria,3T1FV@506|Alcaligenaceae 28216|Betaproteobacteria G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 DYD2_k127_6542490_18 251221.35211453 9.742e-170 548.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria 1117|Cyanobacteria M Substrate binding domain of ABC-type glycine betaine transport system - - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC DYD2_k127_6542490_46 1288494.EBAPG3_14200 8.458e-98 323.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,371U7@32003|Nitrosomonadales 28216|Betaproteobacteria K RNA polymerase sigma factor rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_6542490_88 580332.Slit_1275 1.744e-27 118.0 COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,44VXX@713636|Nitrosomonadales 28216|Betaproteobacteria T PFAM Anti sigma-E protein RseA family protein rseA - - ko:K03597 - - - - ko00000,ko03021 - - - RseA_N DYD2_k127_6542490_61 1266925.JHVX01000002_gene1082 3.691e-79 276.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,3728Y@32003|Nitrosomonadales 28216|Betaproteobacteria T MucB/RseB C-terminal domain rseB - - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C DYD2_k127_6542490_15 1163617.SCD_n01394 1.07e-182 583.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria 28216|Betaproteobacteria O Belongs to the peptidase S1C family degQ - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD2_k127_6542490_2 1288494.EBAPG3_14250 2.106e-319 985.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,372EW@32003|Nitrosomonadales 28216|Betaproteobacteria J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C DYD2_k127_6542490_30 1288494.EBAPG3_14260 2.856e-127 411.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,371PT@32003|Nitrosomonadales 28216|Betaproteobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 DYD2_k127_6542490_92 1163617.SCD_n01398 8.013e-21 98.0 COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria 1224|Proteobacteria NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 DYD2_k127_6542490_60 267608.RSc1063 2.752e-80 275.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,1K0ZU@119060|Burkholderiaceae 28216|Betaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm DYD2_k127_6542490_45 497321.C664_06913 9.03e-100 333.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,2KVT3@206389|Rhodocyclales 206389|Rhodocyclales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 DYD2_k127_6542490_58 1288494.EBAPG3_14290 1.485e-81 278.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,372H0@32003|Nitrosomonadales 28216|Betaproteobacteria L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N DYD2_k127_6542490_51 243365.CV_2070 1.039e-93 316.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,2KPT6@206351|Neisseriales 206351|Neisseriales H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ DYD2_k127_6542490_76 1288494.EBAPG3_14410 1.109e-46 173.0 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,373EI@32003|Nitrosomonadales 28216|Betaproteobacteria I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS DYD2_k127_6542490_25 1163617.SCD_n01410 1.603e-139 456.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria 28216|Betaproteobacteria G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 2.7.8.7,3.2.1.52 ko:K00997,ko:K01207 ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501 M00628 R00022,R01625,R05963,R07809,R07810,R10831 RC00002,RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 DYD2_k127_6542490_55 1123392.AQWL01000004_gene2564 1.007e-84 295.0 COG1230@1|root,COG1230@2|Bacteria,1QUZ5@1224|Proteobacteria,2WGMK@28216|Betaproteobacteria,1KRTJ@119069|Hydrogenophilales 119069|Hydrogenophilales P Cation efflux family - - - - - - - - - - - - Cation_efflux DYD2_k127_6542490_52 323848.Nmul_A1268 3.558e-90 304.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VZ53@28216|Betaproteobacteria,374MG@32003|Nitrosomonadales 28216|Betaproteobacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD2_k127_6542490_97 717785.HYPMC_1169 1.054e-07 55.0 COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2TSUP@28211|Alphaproteobacteria,3N6S7@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria L Uracil-DNA glycosylase ung - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD2_k127_6542490_8 1163617.SCD_n01293 3.005e-240 756.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria 28216|Betaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N DYD2_k127_6542490_57 1288494.EBAPG3_16960 2.282e-83 280.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,372TT@32003|Nitrosomonadales 28216|Betaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD2_k127_6542490_93 1120963.KB894496_gene2675 2.416e-11 67.0 2DS85@1|root,33EYM@2|Bacteria,1NJQN@1224|Proteobacteria,1SHH9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6542490_80 408672.NBCG_02630 4.173e-41 160.0 COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria 201174|Actinobacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_3 DYD2_k127_6542490_48 292.DM42_3784 1.521e-96 331.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,1K8Z6@119060|Burkholderiaceae 28216|Betaproteobacteria M type I secretion membrane fusion - - - ko:K02022,ko:K12537 - M00328 - - ko00000,ko00002,ko02000,ko02044 8.A.1 - - HlyD,HlyD_3 DYD2_k127_6542490_21 765913.ThidrDRAFT_4318 2.016e-157 514.0 COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,1T1HR@1236|Gammaproteobacteria,1X2NS@135613|Chromatiales 135613|Chromatiales V Type I secretion system - - - ko:K16299 ko02010,map02010 M00571 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.110.10 - - ABC_membrane,ABC_tran DYD2_k127_6542490_87 696747.NIES39_B00460 2.281e-29 136.0 COG2931@1|root,COG2931@2|Bacteria,1G5JI@1117|Cyanobacteria,1HART@1150|Oscillatoriales 1117|Cyanobacteria Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - HemolysinCabind DYD2_k127_6542490_85 118168.MC7420_6839 3.822e-34 151.0 COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1GCVD@1117|Cyanobacteria,1HF9Z@1150|Oscillatoriales 1117|Cyanobacteria QU Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - HemolysinCabind DYD2_k127_6542490_83 1038869.AXAN01000045_gene4441 9.511e-36 143.0 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,1K73W@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1178) - - - - - - - - - - - - DUF1178 DYD2_k127_6542490_84 663610.JQKO01000005_gene2457 1.207e-34 137.0 COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2UCYK@28211|Alphaproteobacteria,3NBKA@45404|Beijerinckiaceae 28211|Alphaproteobacteria T Universal stress protein family - - - - - - - - - - - - Usp DYD2_k127_6542490_49 1380394.JADL01000011_gene3854 2.357e-96 322.0 COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,2JSM7@204441|Rhodospirillales 204441|Rhodospirillales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD2_k127_6542490_14 666684.AfiDRAFT_2855 1.25e-187 599.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria,3JUBU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MA20_34330 - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N DYD2_k127_6542490_20 666684.AfiDRAFT_2856 3.516e-163 522.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,3JSVS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD2_k127_6542490_13 666684.AfiDRAFT_2859 5.054e-200 630.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,3JS55@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, middle domain - - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_6542490_91 1173028.ANKO01000041_gene3172 1.868e-24 119.0 COG0642@1|root,COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G3QY@1117|Cyanobacteria,1HA15@1150|Oscillatoriales 1117|Cyanobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_8,PAS_9,Response_reg DYD2_k127_6542490_79 62928.azo1599 1.293e-42 166.0 COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,2KWJN@206389|Rhodocyclales 206389|Rhodocyclales S ankyrin repeat - - - ko:K06867 - - - - ko00000 - - - Ank_2,Ank_3,Ank_4,Ank_5 DYD2_k127_6542490_35 323848.Nmul_A1381 4.085e-115 375.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,372C1@32003|Nitrosomonadales 28216|Betaproteobacteria L TatD related DNase ycfH - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase DYD2_k127_6542490_69 1485544.JQKP01000013_gene1817 5.233e-68 243.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,44VBK@713636|Nitrosomonadales 28216|Betaproteobacteria L TIGRFAM DNA polymerase III, delta prime subunit holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C DYD2_k127_6542490_68 1288494.EBAPG3_14710 1.315e-68 240.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,371TJ@32003|Nitrosomonadales 28216|Betaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin DYD2_k127_6542490_37 159087.Daro_2198 4.755e-109 362.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,2KU8Y@206389|Rhodocyclales 206389|Rhodocyclales S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG DYD2_k127_6542490_64 1163617.SCD_n01529 2.476e-74 266.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2VRAS@28216|Betaproteobacteria 28216|Betaproteobacteria EH PFAM Aminotransferase, class IV pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 DYD2_k127_6542490_12 1163617.SCD_n01531 7.178e-203 641.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria 28216|Betaproteobacteria I catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Ketoacyl-synt_C,ketoacyl-synt DYD2_k127_6542490_82 1286093.C266_07407 7.596e-36 136.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,1K979@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD2_k127_6542490_41 1266925.JHVX01000004_gene1107 1.26e-106 352.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,371Q5@32003|Nitrosomonadales 28216|Betaproteobacteria IQ Short-chain dehydrogenase reductase SDR fabG GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_6542490_32 748247.AZKH_2850 1.906e-120 396.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,2KV8M@206389|Rhodocyclales 206389|Rhodocyclales I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 DYD2_k127_6542490_22 1288494.EBAPG3_13720 2.326e-152 487.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,371X7@32003|Nitrosomonadales 28216|Betaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD2_k127_6542490_23 323848.Nmul_A1071 4.661e-146 470.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,372Q2@32003|Nitrosomonadales 28216|Betaproteobacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis DYD2_k127_6542490_89 228410.NE1644 1.764e-27 111.0 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,373Q2@32003|Nitrosomonadales 28216|Betaproteobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p DYD2_k127_6542490_86 395494.Galf_1556 5.222e-34 137.0 COG1399@1|root,COG1399@2|Bacteria,1PIWK@1224|Proteobacteria,2W7FZ@28216|Betaproteobacteria,44VYP@713636|Nitrosomonadales 28216|Betaproteobacteria S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 DYD2_k127_6542490_73 535289.Dtpsy_2637 1.033e-58 209.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,4ABNK@80864|Comamonadaceae 28216|Betaproteobacteria D Maf-like protein yceF - - ko:K06287 - - - - ko00000 - - - Maf DYD2_k127_6542490_66 395494.Galf_1558 1.551e-69 243.0 COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria,44W80@713636|Nitrosomonadales 28216|Betaproteobacteria H Tetrapyrrole (Corrin/Porphyrin) Methylases rsmI_2 - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase DYD2_k127_6542490_27 1266925.JHVX01000004_gene1115 1.415e-136 441.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,3727I@32003|Nitrosomonadales 28216|Betaproteobacteria OU Peptidase family S49 sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 DYD2_k127_6542490_63 1163617.SCD_n01545 2.41e-75 260.0 COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria 28216|Betaproteobacteria S HAD-superfamily hydrolase, subfamily IA, variant 1 ppaX - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 DYD2_k127_6542490_33 1163617.SCD_n01546 1.065e-117 386.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria 28216|Betaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC - 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD2_k127_6542490_5 748247.AZKH_2859 1.769e-276 876.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,2KV38@206389|Rhodocyclales 206389|Rhodocyclales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD2_k127_6542490_75 765912.Thimo_0530 2.72e-53 199.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1WY50@135613|Chromatiales 135613|Chromatiales T low molecular weight - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc DYD2_k127_6542490_38 1333856.L686_07280 3.155e-108 368.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria,1Z1AG@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_6542490_78 1268622.AVS7_01242 3.579e-45 177.0 COG3181@1|root,COG3181@2|Bacteria,1N1ND@1224|Proteobacteria,2VKD0@28216|Betaproteobacteria,4ACWZ@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6542490_70 309801.trd_0299 8.53e-68 243.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis tlpA - - - - - - - - - - - Redoxin,Thioredoxin_8 DYD2_k127_6542490_99 1408428.JNJP01000008_gene2295 2.018e-06 52.0 COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,42YZP@68525|delta/epsilon subdivisions,2WTUJ@28221|Deltaproteobacteria,2MENN@213115|Desulfovibrionales 28221|Deltaproteobacteria CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - - DYD2_k127_6542490_96 1380393.JHVP01000004_gene567 6.065e-08 59.0 2BZD4@1|root,332J5@2|Bacteria,2IPP3@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - DYD2_k127_6542490_1 1288494.EBAPG3_19920 0.0 1075.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,371QU@32003|Nitrosomonadales 28216|Betaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB DYD2_k127_6542490_17 375286.mma_1247 1.887e-170 546.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2VHNH@28216|Betaproteobacteria,472KW@75682|Oxalobacteraceae 28216|Betaproteobacteria E Aminotransferase class I and II tyrB - 2.6.1.57 ko:K00832 ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040 R00694,R00734,R01731,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_6542490_50 666681.M301_1742 1.885e-94 326.0 COG2982@1|root,COG2982@2|Bacteria,1RD61@1224|Proteobacteria,2VS09@28216|Betaproteobacteria 28216|Betaproteobacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - AsmA,AsmA_2 DYD2_k127_6542490_65 1569209.BBPH01000075_gene777 5.4e-70 256.0 COG3181@1|root,COG3181@2|Bacteria,1MWVK@1224|Proteobacteria,2TXW7@28211|Alphaproteobacteria,2PXZ7@265|Paracoccus 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6542490_10 1232683.ADIMK_4111 2.717e-206 662.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae 1236|Gammaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD2_k127_6542490_42 1380355.JNIJ01000007_gene3231 1.187e-102 344.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3JWN0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_6542490_95 1206739.BAGJ01000121_gene1357 8.815e-09 66.0 COG3473@1|root,COG3473@2|Bacteria,2GKP7@201174|Actinobacteria,4FU91@85025|Nocardiaceae 201174|Actinobacteria Q Maleate cis-trans isomerase - - 5.2.1.1 ko:K01799 ko00650,ko00760,ko01120,map00650,map00760,map01120 M00622 R01087 RC00448 ko00000,ko00001,ko00002,ko01000 - - - Asp_Glu_race DYD2_k127_6542490_44 1121033.AUCF01000001_gene1925 2.271e-100 338.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,2JQ6A@204441|Rhodospirillales 204441|Rhodospirillales S cobalamin synthesis protein - - - - - - - - - - - - CobW_C,cobW DYD2_k127_6542490_19 1120983.KB894577_gene3582 2.442e-164 526.0 COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,1JQCV@119043|Rhodobiaceae 28211|Alphaproteobacteria S LVIVD repeat - - - - - - - - - - - - LVIVD DYD2_k127_6542490_54 639283.Snov_0228 5.143e-87 297.0 COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,2TT7P@28211|Alphaproteobacteria,3F105@335928|Xanthobacteraceae 28211|Alphaproteobacteria C 6-phosphogluconate dehydrogenase NAD-binding MA20_16450 - 1.1.1.411 ko:K08319 - - - - ko00000,ko01000 - - - NAD_binding_11,NAD_binding_2 DYD2_k127_6542490_56 1120956.JHZK01000002_gene996 9.536e-84 286.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein dddQ - - ko:K11312 - - - - ko00000 - - - Cupin_2,DUF4437 DYD2_k127_6542490_59 1125973.JNLC01000011_gene588 1.351e-80 279.0 COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,2TRA1@28211|Alphaproteobacteria,3JSTX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K LysR family MA20_04505 - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_6542490_24 1125973.JNLC01000011_gene593 8.521e-144 464.0 COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2TV6R@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Oxidoreductase ligC - 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_6542490_16 1125973.JNLC01000011_gene592 1.474e-177 562.0 COG0673@1|root,COG0673@2|Bacteria,1QSNV@1224|Proteobacteria,2TUMB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_6542490_7 1125973.JNLC01000010_gene1417 9.193e-241 755.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,3JZ96@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD2_k127_6542490_53 639283.Snov_0188 5.341e-90 314.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3EYRF@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6542490_62 1244869.H261_19868 1.067e-76 273.0 COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria,2JT4J@204441|Rhodospirillales 204441|Rhodospirillales E Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 DYD2_k127_6542490_74 471853.Bcav_0076 1.509e-54 208.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria 201174|Actinobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N DYD2_k127_6542490_100 595460.RRSWK_03548 0.0001721 50.0 COG2128@1|root,COG2128@2|Bacteria,2IYUM@203682|Planctomycetes 203682|Planctomycetes O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD2_k127_6542490_94 1382306.JNIM01000001_gene4065 1.183e-09 64.0 COG2128@1|root,COG2128@2|Bacteria,2G8VF@200795|Chloroflexi 200795|Chloroflexi S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - - DYD2_k127_6542490_36 1187851.A33M_2610 3.682e-113 374.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria 28211|Alphaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_6542490_29 1096930.L284_22405 6.706e-135 436.0 COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,2TW55@28211|Alphaproteobacteria,2KAFH@204457|Sphingomonadales 204457|Sphingomonadales EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_6542490_43 1123060.JONP01000024_gene2531 1.656e-100 337.0 COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,2U12U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_6542490_6 1128421.JAGA01000002_gene214 5.128e-268 833.0 COG1274@1|root,COG1274@2|Bacteria,2NQRD@2323|unclassified Bacteria 2|Bacteria C Phosphoenolpyruvate carboxykinase C-terminal P-loop domain pckG GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771 4.1.1.32,4.1.1.49 ko:K01596,ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003,M00170 R00341,R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2638 PEPCK_ATP,PEPCK_C,PEPCK_N DYD2_k127_6542623_20 583345.Mmol_0328 1.271e-17 89.0 COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,2KMIM@206350|Nitrosomonadales 206350|Nitrosomonadales C PFAM Cytochrome C1 - - - ko:K00413 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002 - - - Cytochrom_C1 DYD2_k127_6542623_0 1095769.CAHF01000003_gene986 2.073e-208 657.0 COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,4727H@75682|Oxalobacteraceae 28216|Betaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrome_B DYD2_k127_6542623_10 864051.BurJ1DRAFT_1232 1.375e-81 276.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,1KJ5I@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N DYD2_k127_6542623_3 1163617.SCD_n00599 9.549e-159 510.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria 28216|Betaproteobacteria O Belongs to the peptidase S1C family degQ - - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 DYD2_k127_6542623_7 375286.mma_3277 2.54e-95 318.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,472WE@75682|Oxalobacteraceae 28216|Betaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC DYD2_k127_6542623_16 640081.Dsui_1423 1.681e-32 131.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KWT9@206389|Rhodocyclales 206389|Rhodocyclales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD2_k127_6542623_18 580332.Slit_0632 1.947e-21 95.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,44W2X@713636|Nitrosomonadales 28216|Betaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD2_k127_6542623_15 557598.LHK_00192 1.634e-33 138.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,2KRIM@206351|Neisseriales 206351|Neisseriales E Psort location Cytoplasmic, score hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH DYD2_k127_6542623_13 580332.Slit_0629 2.141e-59 207.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,44VV6@713636|Nitrosomonadales 28216|Betaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH DYD2_k127_6542623_5 261292.Nit79A3_1044 7.525e-125 403.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,3724H@32003|Nitrosomonadales 28216|Betaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD2_k127_6542623_6 1266925.JHVX01000004_gene1304 2.35e-121 397.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,371YC@32003|Nitrosomonadales 28216|Betaproteobacteria E TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD2_k127_6542623_8 76114.ebA1295 2.014e-92 308.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,2KUCS@206389|Rhodocyclales 206389|Rhodocyclales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase DYD2_k127_6542623_9 1000565.METUNv1_02433 5.434e-92 306.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,2KV7E@206389|Rhodocyclales 206389|Rhodocyclales E imidazoleglycerol-phosphate dehydratase hisB - 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD DYD2_k127_6542623_4 1266925.JHVX01000004_gene1301 3.694e-137 444.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,371PJ@32003|Nitrosomonadales 28216|Betaproteobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_6542623_2 557598.LHK_00184 1.096e-190 606.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,2KPF7@206351|Neisseriales 206351|Neisseriales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh DYD2_k127_6542623_1 1163617.SCD_n00584 8.766e-191 605.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria 28216|Betaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase DYD2_k127_6542623_17 292415.Tbd_1892 8.373e-28 121.0 COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,1KTA1@119069|Hydrogenophilales 119069|Hydrogenophilales K BolA-like protein - - - - - - - - - - - - BolA DYD2_k127_6542623_19 323848.Nmul_A2745 3.915e-19 96.0 COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,2WB4V@28216|Betaproteobacteria,373NW@32003|Nitrosomonadales 28216|Betaproteobacteria S transporter antisigma-factor antagonist STAS - - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 DYD2_k127_6542623_12 640081.Dsui_1402 1.592e-62 221.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KW7C@206389|Rhodocyclales 206389|Rhodocyclales Q ABC-type transport system involved in resistance to organic solvents, auxiliary component - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD2_k127_6542623_14 292415.Tbd_1898 1.673e-58 207.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1KRP2@119069|Hydrogenophilales 119069|Hydrogenophilales Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD2_k127_6542623_11 1123392.AQWL01000001_gene1546 5.132e-68 232.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,1KRYU@119069|Hydrogenophilales 119069|Hydrogenophilales Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD2_k127_6556388_28 1380394.JADL01000003_gene4831 2.189e-45 168.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2JSY5@204441|Rhodospirillales 204441|Rhodospirillales C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR,POR_N DYD2_k127_6556388_1 1123073.KB899242_gene1461 0.0 1020.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1XA61@135614|Xanthomonadales 135614|Xanthomonadales CE Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2 DYD2_k127_6556388_19 626887.J057_07291 1.481e-96 322.0 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,4670C@72275|Alteromonadaceae 1236|Gammaproteobacteria P Integral membrane protein TerC family ygdQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - TerC DYD2_k127_6556388_20 1095769.CAHF01000011_gene2117 4.536e-90 308.0 COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2VIUS@28216|Betaproteobacteria 28216|Betaproteobacteria S N-terminal half of MaoC dehydratase - - 4.2.1.153,4.2.1.56 ko:K09709,ko:K18291 ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200 M00376 R02491,R09282 RC00730,RC02479 ko00000,ko00001,ko00002,ko01000 - - - MaoC_dehydrat_N DYD2_k127_6556388_27 1396141.BATP01000003_gene5178 7.231e-55 204.0 COG3509@1|root,COG3509@2|Bacteria,46X2M@74201|Verrucomicrobia,2IW7R@203494|Verrucomicrobiae 203494|Verrucomicrobiae Q depolymerase - - - - - - - - - - - - - DYD2_k127_6556388_5 331869.BAL199_12941 6.524e-186 589.0 COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2VFEC@28211|Alphaproteobacteria,4BQWR@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 DYD2_k127_6556388_17 331869.BAL199_12936 1.162e-106 353.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,4BREC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD2_k127_6556388_13 331869.BAL199_12931 5.974e-140 454.0 COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,2TVFT@28211|Alphaproteobacteria,4BRDF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid transport system permease - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 DYD2_k127_6556388_16 1469245.JFBG01000052_gene2168 4.059e-114 375.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,1RQU2@1236|Gammaproteobacteria,1X2CD@135613|Chromatiales 135613|Chromatiales E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C DYD2_k127_6556388_15 1469245.JFBG01000052_gene2167 4.244e-123 401.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Branched-chain amino acid transport - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran DYD2_k127_6556388_2 472759.Nhal_1635 1.554e-228 729.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria,1WXPA@135613|Chromatiales 135613|Chromatiales I PFAM SNARE associated Golgi protein - - - - - - - - - - - - PLDc,PLDc_2,SNARE_assoc DYD2_k127_6556388_21 1288494.EBAPG3_1030 6.267e-78 268.0 COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VQ9I@28216|Betaproteobacteria,371PA@32003|Nitrosomonadales 28216|Betaproteobacteria L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos DYD2_k127_6556388_11 1288494.EBAPG3_28900 1.23e-143 467.0 COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,2VIYG@28216|Betaproteobacteria,374KC@32003|Nitrosomonadales 28216|Betaproteobacteria M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 DYD2_k127_6556388_18 247490.KSU1_C1149 5.824e-102 336.0 COG1136@1|root,COG1136@2|Bacteria,2IWZ1@203682|Planctomycetes 203682|Planctomycetes V ABC-type antimicrobial peptide transport system, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_6556388_8 1288494.EBAPG3_28930 3.379e-166 530.0 COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,2VNEP@28216|Betaproteobacteria 28216|Betaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_6556388_10 671143.DAMO_0040 1.176e-162 531.0 COG0577@1|root,COG0577@2|Bacteria,2NQJU@2323|unclassified Bacteria 2|Bacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_6556388_22 1288494.EBAPG3_28950 1.12e-77 263.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,372JP@32003|Nitrosomonadales 28216|Betaproteobacteria F Nudix hydrolase nudC_1 - - - - - - - - - - - NUDIX,Nudix_N_2 DYD2_k127_6556388_7 1123393.KB891317_gene2264 3.3e-175 559.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria,1KSUB@119069|Hydrogenophilales 119069|Hydrogenophilales S ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA_5 DYD2_k127_6556388_12 765913.ThidrDRAFT_2532 6.676e-142 472.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,1RXX2@1236|Gammaproteobacteria,1WX24@135613|Chromatiales 135613|Chromatiales S VWA-like domain (DUF2201) - - - - - - - - - - - - DUF2201,DUF2201_N DYD2_k127_6556388_24 946362.XP_004989089.1 1.179e-61 224.0 COG3509@1|root,2SBTI@2759|Eukaryota,39SMX@33154|Opisthokonta 33154|Opisthokonta Q xylan catabolic process - - 3.1.1.73 ko:K09252 - - - - ko00000,ko01000 - - - Esterase_phd DYD2_k127_6556388_14 977880.RALTA_A0734 2.407e-138 450.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,1K1ZD@119060|Burkholderiaceae 28216|Betaproteobacteria S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like DYD2_k127_6556388_3 1485544.JQKP01000001_gene1143 2.402e-205 653.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,44V57@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase DYD2_k127_6556388_26 582744.Msip34_0909 1.932e-57 201.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KMZX@206350|Nitrosomonadales 206350|Nitrosomonadales K Belongs to the P(II) protein family - - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II DYD2_k127_6556388_29 292415.Tbd_1000 1.09e-43 179.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,1KTBK@119069|Hydrogenophilales 119069|Hydrogenophilales S Small MutS-related domain - - - - - - - - - - - - Smr DYD2_k127_6556388_9 1266925.JHVX01000008_gene346 4.5e-166 526.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,372UH@32003|Nitrosomonadales 28216|Betaproteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD2_k127_6556388_25 522306.CAP2UW1_2298 2.543e-61 223.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator crp fnr family crp - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,HTH_Crp_2,cNMP_binding DYD2_k127_6556388_30 1175306.GWL_44540 8.934e-37 152.0 COG4254@1|root,COG4254@2|Bacteria,1R2K9@1224|Proteobacteria,2WICR@28216|Betaproteobacteria,4796C@75682|Oxalobacteraceae 28216|Betaproteobacteria S FecR protein - - - - - - - - - - - - FecR DYD2_k127_6556388_0 1288494.EBAPG3_6760 0.0 1023.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,372D7@32003|Nitrosomonadales 28216|Betaproteobacteria D PFAM cell divisionFtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma DYD2_k127_6556388_31 748280.NH8B_0762 0.0005841 49.0 28WUG@1|root,2ZITX@2|Bacteria,1P7A0@1224|Proteobacteria,2W6CM@28216|Betaproteobacteria,2KTNV@206351|Neisseriales 206351|Neisseriales - - - - - - - - - - - - - - - DYD2_k127_6556388_23 395494.Galf_0253 2.655e-65 230.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,44VR2@713636|Nitrosomonadales 28216|Betaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA DYD2_k127_6556388_4 1163617.SCD_n01184 6.406e-198 630.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria 28216|Betaproteobacteria L AAA ATPase central domain protein rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N DYD2_k127_6556388_6 1031711.RSPO_c01119 6.494e-185 593.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,1K2ZR@119060|Burkholderiaceae 28216|Betaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b DYD2_k127_6564219_0 1028800.RG540_CH33990 5.126e-199 642.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4B7Q0@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_6618301_1 1123401.JHYQ01000001_gene1788 4.429e-15 81.0 COG1266@1|root,COG1266@2|Bacteria,1QSFU@1224|Proteobacteria 1224|Proteobacteria S CAAX amino Terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi DYD2_k127_6618301_0 1131553.JIBI01000010_gene1373 0.0 1357.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,372NK@32003|Nitrosomonadales 28216|Betaproteobacteria H Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans DYD2_k127_66350_0 153948.NAL212_2520 3.881e-190 598.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,372Q8@32003|Nitrosomonadales 28216|Betaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD2_k127_66350_20 1121121.KB894333_gene4598 8.339e-06 52.0 2ED1A@1|root,336Y8@2|Bacteria,1VNP3@1239|Firmicutes,4HRCX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - DYD2_k127_66350_9 987059.RBXJA2T_01620 2.244e-100 340.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,1KKCR@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Von Willebrand factor type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 DYD2_k127_66350_7 1095769.CAHF01000011_gene2300 2.241e-119 391.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2W98D@28216|Betaproteobacteria,476N1@75682|Oxalobacteraceae 28216|Betaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - DUF58 DYD2_k127_66350_4 1366050.N234_28380 2.544e-163 520.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,1KBIY@119060|Burkholderiaceae 28216|Betaproteobacteria S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD2_k127_66350_11 1123504.JQKD01000012_gene1343 4.987e-92 313.0 COG0265@1|root,COG0265@2|Bacteria,1QWA4@1224|Proteobacteria,2VK6X@28216|Betaproteobacteria,4A9X2@80864|Comamonadaceae 28216|Betaproteobacteria O peptidase S1 and S6, chymotrypsin Hap - - - - - - - - - - - - Trypsin_2 DYD2_k127_66350_8 1095769.CAHF01000011_gene2301 6.288e-116 384.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria 28216|Betaproteobacteria S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 DYD2_k127_66350_12 1205680.CAKO01000037_gene1311 2.58e-87 299.0 COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,2JW8Q@204441|Rhodospirillales 204441|Rhodospirillales I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - - - - - - - - - - 3HCDH,3HCDH_N DYD2_k127_66350_15 1510531.JQJJ01000010_gene2442 3.339e-74 265.0 COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,3K48K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Methyltransferase domain - - - - - - - - - - - - Methyltransf_31 DYD2_k127_66350_6 1054213.HMPREF9946_01994 1.842e-135 442.0 COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2TVJ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria C L-carnitine dehydratase bile acid-inducible protein - - - - - - - - - - - - CoA_transf_3 DYD2_k127_66350_13 1095769.CAHF01000011_gene2117 4.481e-86 293.0 COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2VIUS@28216|Betaproteobacteria 28216|Betaproteobacteria S N-terminal half of MaoC dehydratase - - 4.2.1.153,4.2.1.56 ko:K09709,ko:K18291 ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200 M00376 R02491,R09282 RC00730,RC02479 ko00000,ko00001,ko00002,ko01000 - - - MaoC_dehydrat_N DYD2_k127_66350_10 1054213.HMPREF9946_00792 3.621e-92 316.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the HpcH HpaI aldolase family - - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI DYD2_k127_66350_3 1297865.APJD01000049_gene5506 3.115e-164 527.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3JTSN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD2_k127_66350_16 76114.p2A140 2.951e-71 250.0 COG1414@1|root,COG1414@2|Bacteria,1NCG5@1224|Proteobacteria,2VWMK@28216|Betaproteobacteria,2KZKC@206389|Rhodocyclales 206389|Rhodocyclales K helix_turn_helix isocitrate lyase regulation - - - - - - - - - - - - HTH_IclR DYD2_k127_66350_5 1175306.GWL_24680 7.018e-140 451.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria,47299@75682|Oxalobacteraceae 28216|Betaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30,5.4.2.9 ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 - R00409,R00661 RC00286,RC00287,RC02792 ko00000,ko00001,ko01000 - - - PEP_mutase DYD2_k127_66350_2 323848.Nmul_A2642 2.518e-172 550.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,372JY@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH DYD2_k127_66350_1 999541.bgla_1g04410 1.933e-173 551.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,1K2D1@119060|Burkholderiaceae 28216|Betaproteobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD2_k127_66350_14 1385515.N791_02130 2.206e-82 282.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales 135614|Xanthomonadales J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 DYD2_k127_66350_18 640081.Dsui_0118 7.418e-44 165.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,2KWQF@206389|Rhodocyclales 206389|Rhodocyclales C Belongs to the glutaredoxin family. Monothiol subfamily - - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin DYD2_k127_66350_19 1265505.ATUG01000001_gene4248 1.229e-38 155.0 COG0730@1|root,COG0730@2|Bacteria,1RJXP@1224|Proteobacteria,42UVE@68525|delta/epsilon subdivisions 1224|Proteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE DYD2_k127_66350_17 1249627.D779_0010 9.71e-51 190.0 COG5473@1|root,COG5473@2|Bacteria,1R8RR@1224|Proteobacteria,1S0TC@1236|Gammaproteobacteria,1WWZI@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD2_k127_6648204_20 667632.KB890165_gene2485 3.065e-46 177.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1K035@119060|Burkholderiaceae 28216|Betaproteobacteria C CoA-binding domain protein - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig DYD2_k127_6648204_19 1121468.AUBR01000028_gene1511 1.595e-49 181.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,42FXS@68295|Thermoanaerobacterales 186801|Clostridia C TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - 6.2.1.13 ko:K01905,ko:K22224 ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120 - R00229,R00920 RC00004,RC00012,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD2_k127_6648204_23 1121091.AUMP01000002_gene1849 1.415e-38 159.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli 91061|Bacilli I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_6648204_35 411902.CLOBOL_01805 2.148e-07 62.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - 5.3.3.19 ko:K19547 ko01130,map01130 M00787 - - ko00000,ko00001,ko00002,ko01000 - - - Cupin_2 DYD2_k127_6648204_12 1268622.AVS7_02817 9.2e-92 310.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,4AB9Z@80864|Comamonadaceae 1224|Proteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit - - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA,Succ_CoA_lig DYD2_k127_6648204_13 1121106.JQKB01000139_gene4054 3.319e-84 293.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - - - - - - - - - - ATP-grasp_2 DYD2_k127_6648204_14 1207063.P24_00920 2.683e-73 255.0 COG1024@1|root,COG1024@2|Bacteria,1PU1Q@1224|Proteobacteria,2TSW6@28211|Alphaproteobacteria,2JS2P@204441|Rhodospirillales 204441|Rhodospirillales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD2_k127_6648204_25 1123368.AUIS01000024_gene956 7.137e-36 154.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,1RR26@1236|Gammaproteobacteria,2NC5V@225057|Acidithiobacillales 225057|Acidithiobacillales O Glutathione S-transferase, N-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N_3 DYD2_k127_6648204_34 29581.BW37_00058 4.079e-11 67.0 COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,2VWCP@28216|Betaproteobacteria,4754M@75682|Oxalobacteraceae 28216|Betaproteobacteria S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc DYD2_k127_6648204_28 1282876.BAOK01000001_gene3650 5.805e-24 103.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,4BQXE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K Cold shock protein domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD2_k127_6648204_26 123899.JPQP01000002_gene832 5.829e-31 124.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,3T4E3@506|Alcaligenaceae 28216|Betaproteobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA2 - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a DYD2_k127_6648204_27 522306.CAP2UW1_1013 1.721e-26 112.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria 1224|Proteobacteria S PFAM RNP-1 like RNA-binding protein - - - - - - - - - - - - RRM_1 DYD2_k127_6648204_30 331869.BAL199_16313 3.264e-19 93.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD2_k127_6648204_15 123899.JPQP01000020_gene1939 4.643e-61 224.0 COG2267@1|root,COG2267@2|Bacteria,1P7JV@1224|Proteobacteria,2VR0X@28216|Betaproteobacteria,3T88E@506|Alcaligenaceae 28216|Betaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD2_k127_6648204_21 1123400.KB904813_gene2988 1.764e-42 163.0 COG4403@1|root,COG4403@2|Bacteria,1NCPK@1224|Proteobacteria,1SCTX@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Lanthionine synthetase C family protein - - - - - - - - - - - - - DYD2_k127_6648204_31 326297.Sama_3191 3.237e-18 93.0 2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,1SGMZ@1236|Gammaproteobacteria,2QCVX@267890|Shewanellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF3012) - - - - - - - - - - - - DUF3012 DYD2_k127_6648204_0 1126627.BAWE01000006_gene6770 1.027e-230 724.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3JSXN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_6648204_17 196367.JNFG01000003_gene5666 1.749e-58 210.0 COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2VQ61@28216|Betaproteobacteria,1K928@119060|Burkholderiaceae 28216|Betaproteobacteria EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_C DYD2_k127_6648204_18 196367.JNFG01000003_gene5665 9.362e-58 206.0 COG4032@1|root,COG4032@2|Bacteria,1P0HU@1224|Proteobacteria,2VQMS@28216|Betaproteobacteria,1K8XM@119060|Burkholderiaceae 28216|Betaproteobacteria S Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - - - - - - - - - - TPP_enzyme_N DYD2_k127_6648204_4 631454.N177_0160 3.227e-188 599.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,1JPU6@119043|Rhodobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD2_k127_6648204_36 1547437.LL06_25220 0.0001474 50.0 2D22U@1|root,32TC0@2|Bacteria,1N3XM@1224|Proteobacteria,2VG4Q@28211|Alphaproteobacteria,43RNC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD2_k127_6648204_10 1120983.KB894578_gene3830 3.122e-98 344.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TTFX@28211|Alphaproteobacteria,1JPR6@119043|Rhodobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6648204_7 1038859.AXAU01000002_gene322 6.69e-151 484.0 COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2TT57@28211|Alphaproteobacteria,3JSAU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_6648204_16 1038859.AXAU01000002_gene323 4.098e-59 209.0 COG3193@1|root,COG3193@2|Bacteria 2|Bacteria - - - - - ko:K11477 - - - - ko00000 - - - Haem_degrading DYD2_k127_6648204_1 757424.Hsero_2798 3.729e-205 653.0 COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VKD1@28216|Betaproteobacteria,475B2@75682|Oxalobacteraceae 28216|Betaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain acd12 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_6648204_6 279714.FuraDRAFT_0675 3.841e-161 517.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KQPG@206351|Neisseriales 28216|Betaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD2_k127_6648204_8 314270.RB2083_2624 3.073e-144 466.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,3ZGRW@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C NADH flavin - - - - - - - - - - - - Oxidored_FMN DYD2_k127_6648204_3 1123239.KB898631_gene2323 5.93e-197 619.0 COG4948@1|root,COG4948@2|Bacteria,1U140@1239|Firmicutes,4HAT9@91061|Bacilli 91061|Bacilli M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C DYD2_k127_6648204_33 1146883.BLASA_1458 3.729e-13 76.0 COG0715@1|root,COG0715@2|Bacteria,2GN9B@201174|Actinobacteria,4EWIV@85013|Frankiales 201174|Actinobacteria P Protein of unknown function (DUF3500) - - - - - - - - - - - - DUF3500 DYD2_k127_6648204_37 1089547.KB913013_gene3290 0.0001663 49.0 COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,47JPM@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF3500) - - - - - - - - - - - - DUF3500 DYD2_k127_6648204_29 765912.Thimo_3345 2.444e-19 94.0 2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,1SD5T@1236|Gammaproteobacteria,1X269@135613|Chromatiales 135613|Chromatiales S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 DYD2_k127_6648204_9 1120956.JHZK01000010_gene2737 9.416e-137 446.0 COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,2VFXG@28211|Alphaproteobacteria,1JPY6@119043|Rhodobiaceae 28211|Alphaproteobacteria CE Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.42,1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 ko:K00031,ko:K00052,ko:K07246 ko00020,ko00290,ko00480,ko00630,ko00650,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00630,map00650,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00432,M00535,M00740 R00215,R00267,R00268,R00994,R01751,R01899,R02545,R04426,R06180,R10052 RC00001,RC00084,RC00105,RC00114,RC00417,RC00594,RC00626,RC02801,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD2_k127_6648204_22 365046.Rta_34800 1.219e-40 159.0 COG0725@1|root,COG0725@2|Bacteria,1NY9R@1224|Proteobacteria,2VRYF@28216|Betaproteobacteria,4ADYN@80864|Comamonadaceae 28216|Betaproteobacteria P Bacterial extracellular solute-binding protein - - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 DYD2_k127_6648204_24 266265.Bxe_A2048 2.401e-37 145.0 COG0346@1|root,COG0346@2|Bacteria,1PK3B@1224|Proteobacteria,2W8DQ@28216|Betaproteobacteria,1K798@119060|Burkholderiaceae 28216|Betaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD2_k127_6648204_2 1125973.JNLC01000018_gene2320 2.369e-200 635.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD2_k127_6648204_11 1125973.JNLC01000018_gene2319 1.307e-95 323.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2U8QU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_6648204_5 1380394.JADL01000001_gene2962 2.943e-180 575.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MmgE PrpD family protein - - - - - - - - - - - - MmgE_PrpD DYD2_k127_6653285_67 768671.ThimaDRAFT_2842 5.263e-07 51.0 COG3247@1|root,COG3247@2|Bacteria,1RFIH@1224|Proteobacteria,1S6XJ@1236|Gammaproteobacteria,1WYQ5@135613|Chromatiales 135613|Chromatiales S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 DYD2_k127_6653285_18 1163617.SCD_n02221 9.054e-168 538.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria 28216|Betaproteobacteria H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C DYD2_k127_6653285_58 580332.Slit_0948 2.525e-45 169.0 COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,44VXI@713636|Nitrosomonadales 28216|Betaproteobacteria H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK DYD2_k127_6653285_40 1095769.CAHF01000013_gene3343 2.557e-84 287.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,473B3@75682|Oxalobacteraceae 28216|Betaproteobacteria F Deoxynucleoside kinase dgk - - - - - - - - - - - dNK DYD2_k127_6653285_30 1485544.JQKP01000019_gene16 9.728e-111 363.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,44V0C@713636|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf DYD2_k127_6653285_34 522306.CAP2UW1_2451 1.716e-99 336.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,1KPX8@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase DYD2_k127_6653285_23 1163617.SCD_n02213 1.772e-128 423.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria 28216|Betaproteobacteria J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth DYD2_k127_6653285_16 1163617.SCD_n02210 1.748e-181 573.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT DYD2_k127_6653285_60 1000565.METUNv1_00172 8.32e-36 138.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,2KWNW@206389|Rhodocyclales 206389|Rhodocyclales U preprotein translocase subunit YajC yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC DYD2_k127_6653285_5 1288494.EBAPG3_27530 1.373e-274 857.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,371VT@32003|Nitrosomonadales 28216|Betaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG DYD2_k127_6653285_24 640081.Dsui_3326 5.502e-127 413.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,2KVVV@206389|Rhodocyclales 206389|Rhodocyclales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG DYD2_k127_6653285_42 323848.Nmul_A2425 1.2e-81 276.0 COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,372D5@32003|Nitrosomonadales 28216|Betaproteobacteria S SNARE associated Golgi protein dedA - - ko:K03975 - - - - ko00000 - - - SNARE_assoc DYD2_k127_6653285_43 1123393.KB891328_gene562 1.831e-81 280.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,1KSZH@119069|Hydrogenophilales 119069|Hydrogenophilales O Tetratricopeptide repeat - - - - - - - - - - - - TPR_19,TPR_20,Thioredoxin DYD2_k127_6653285_10 1288494.EBAPG3_1990 1.284e-208 656.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,3721Y@32003|Nitrosomonadales 28216|Betaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 DYD2_k127_6653285_32 1125973.JNLC01000018_gene2316 1.954e-101 347.0 COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,3K00D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD DYD2_k127_6653285_17 504832.OCAR_6181 1.054e-168 542.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,3JVVF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD2_k127_6653285_48 768671.ThimaDRAFT_3399 2.627e-67 239.0 COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,1SZQ8@1236|Gammaproteobacteria,1WZ07@135613|Chromatiales 135613|Chromatiales EG EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_6653285_65 522306.CAP2UW1_3268 4.093e-10 63.0 2E827@1|root,332G9@2|Bacteria,1ND10@1224|Proteobacteria,2VW87@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3567) - - - - - - - - - - - - DUF3567 DYD2_k127_6653285_19 1123368.AUIS01000019_gene1225 9.493e-161 519.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1T3CM@1236|Gammaproteobacteria,2NDP9@225057|Acidithiobacillales 225057|Acidithiobacillales L GIY-YIG type nucleases (URI domain) - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T DYD2_k127_6653285_38 640081.Dsui_0127 3.359e-88 298.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2VHB6@28216|Betaproteobacteria,2KUMZ@206389|Rhodocyclales 206389|Rhodocyclales K Transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR DYD2_k127_6653285_50 977880.RALTA_A0953 1.748e-65 230.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,1K33N@119060|Burkholderiaceae 28216|Betaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N DYD2_k127_6653285_41 1380394.JADL01000003_gene5080 4.42e-83 289.0 COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,2JRVV@204441|Rhodospirillales 204441|Rhodospirillales O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2,Trypsin_2 DYD2_k127_6653285_52 398578.Daci_3115 6.552e-61 214.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2VJSF@28216|Betaproteobacteria,4AC9W@80864|Comamonadaceae 28216|Betaproteobacteria P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C DYD2_k127_6653285_29 93220.LV28_24465 5.099e-111 365.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VNV2@28216|Betaproteobacteria,1K0C9@119060|Burkholderiaceae 28216|Betaproteobacteria C Cysteine-rich domain - - - ko:K18928 - - - - ko00000 - - - CCG DYD2_k127_6653285_28 1502851.FG93_04345 3.827e-111 374.0 COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,2TVRD@28211|Alphaproteobacteria,3K5Z9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - ApbA,ApbA_C DYD2_k127_6653285_25 296591.Bpro_0536 5.644e-124 407.0 COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2VJX2@28216|Betaproteobacteria,4ADRU@80864|Comamonadaceae 28216|Betaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 5.1.2.2 ko:K01781 ko00627,ko01120,map00627,map01120 - R03791,R04161 RC00998 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N DYD2_k127_6653285_66 1207063.P24_08464 6.336e-09 59.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria,2JS66@204441|Rhodospirillales 204441|Rhodospirillales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD2_k127_6653285_14 1218076.BAYB01000003_gene649 1.455e-184 588.0 COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,2VJ3Y@28216|Betaproteobacteria,1K165@119060|Burkholderiaceae 28216|Betaproteobacteria C 4Fe-4S ferredoxin, iron-sulfur binding - - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom DYD2_k127_6653285_8 290397.Adeh_2245 2.691e-222 704.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2YTUB@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde dehydrogenase family mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_6653285_49 395019.Bmul_2202 3.053e-67 235.0 COG1556@1|root,COG1556@2|Bacteria,1R4TE@1224|Proteobacteria,2VJCF@28216|Betaproteobacteria,1K1I9@119060|Burkholderiaceae 28216|Betaproteobacteria S LUD domain - - - ko:K00782 - - - - ko00000 - - - LUD_dom DYD2_k127_6653285_46 1232410.KI421417_gene2753 9.036e-73 256.0 COG1877@1|root,COG1877@2|Bacteria,1PF7W@1224|Proteobacteria,42QT9@68525|delta/epsilon subdivisions,2WNR9@28221|Deltaproteobacteria,43UM2@69541|Desulfuromonadales 28221|Deltaproteobacteria G Removes the phosphate from trehalose 6-phosphate to produce free trehalose otsB - 3.1.3.12 ko:K01087 ko00500,ko01100,map00500,map01100 - R02778 RC00017 ko00000,ko00001,ko01000 - - - Trehalose_PPase DYD2_k127_6653285_3 1163617.SCD_n02426 3.168e-315 977.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria 28216|Betaproteobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 DYD2_k127_6653285_4 472759.Nhal_2490 1.357e-300 938.0 COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1WX35@135613|Chromatiales 135613|Chromatiales G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 DYD2_k127_6653285_1 543728.Vapar_1980 0.0 1510.0 COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,2VHW5@28216|Betaproteobacteria,4ABG1@80864|Comamonadaceae 28216|Betaproteobacteria G SMART alpha amylase catalytic sub domain treS - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - APH,Alpha-amylase,Malt_amylase_C DYD2_k127_6653285_44 338969.Rfer_2159 1.108e-79 279.0 COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2WFQP@28216|Betaproteobacteria,4ABHJ@80864|Comamonadaceae 28216|Betaproteobacteria M PFAM Conserved TM helix repeat-containing protein - - - - - - - - - - - - TM_helix DYD2_k127_6653285_2 1163617.SCD_n02432 0.0 1122.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2VH8E@28216|Betaproteobacteria 28216|Betaproteobacteria G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 DYD2_k127_6653285_7 765912.Thimo_2343 9.187e-246 781.0 COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1RP2N@1236|Gammaproteobacteria,1WWIM@135613|Chromatiales 135613|Chromatiales G TIGRFAM malto-oligosyltrehalose trehalohydrolase - - 3.2.1.141 ko:K01236 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11256 RC00049 ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3459 DYD2_k127_6653285_0 1163617.SCD_n02434 0.0 1811.0 COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,1QTVJ@1224|Proteobacteria,2WGPV@28216|Betaproteobacteria 28216|Betaproteobacteria G 4-alpha-glucanotransferase treY - 2.4.1.25,5.4.99.15 ko:K00705,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000 - GH13,GH77 - Alpha-amylase,Glyco_hydro_77 DYD2_k127_6653285_36 518766.Rmar_0905 1.886e-96 327.0 COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes 976|Bacteroidetes M mechanosensitive ion channel - - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel DYD2_k127_6653285_15 690850.Desaf_3108 1.667e-183 588.0 COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2MA96@213115|Desulfovibrionales 28221|Deltaproteobacteria G PFAM Glycosyl transferase, family 20 otsAB - 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K16055 ko00500,ko01100,map00500,map01100 - R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20,S6PP,Trehalose_PPase DYD2_k127_6653285_39 640081.Dsui_3393 5.165e-87 301.0 COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,2VKV2@28216|Betaproteobacteria,2KWJB@206389|Rhodocyclales 206389|Rhodocyclales P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger DYD2_k127_6653285_22 375286.mma_2607 9.595e-133 435.0 COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2VK27@28216|Betaproteobacteria,47394@75682|Oxalobacteraceae 28216|Betaproteobacteria H ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity ybdK - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 DYD2_k127_6653285_35 62928.azo2275 1.947e-97 325.0 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VMMI@28216|Betaproteobacteria,2KW7J@206389|Rhodocyclales 206389|Rhodocyclales S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 DYD2_k127_6653285_21 580332.Slit_2777 4.019e-146 479.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria 28216|Betaproteobacteria O serine protease nfeD - - ko:K07403 - - - - ko00000 - - - NfeD DYD2_k127_6653285_27 859657.RPSI07_2541 7.699e-114 374.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria,1K11F@119060|Burkholderiaceae 28216|Betaproteobacteria O PFAM band 7 protein - - - - - - - - - - - - Band_7 DYD2_k127_6653285_56 1123368.AUIS01000030_gene1245 5.563e-51 188.0 COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - MarR,MarR_2 DYD2_k127_6653285_57 94624.Bpet1981 1.414e-47 179.0 COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,2VW3B@28216|Betaproteobacteria,3T3T6@506|Alcaligenaceae 28216|Betaproteobacteria K L-2,4-diaminobutyric acid acetyltransferase ectA - 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 DYD2_k127_6653285_11 257310.BB3219 1.335e-199 630.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2VI11@28216|Betaproteobacteria,3T2Y8@506|Alcaligenaceae 28216|Betaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family ectB - 2.6.1.76 ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 M00033 R06977 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_6653285_53 1121090.KB894694_gene2159 2.407e-59 209.0 COG1917@1|root,COG1917@2|Bacteria,1V719@1239|Firmicutes,4HIPQ@91061|Bacilli,1ZGMT@1386|Bacillus 91061|Bacilli S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant ectC - 4.2.1.108 ko:K06720 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06979 RC01729 ko00000,ko00001,ko00002,ko01000 - - - Ectoine_synth DYD2_k127_6653285_26 742159.HMPREF0004_2491 2.812e-116 382.0 COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2VM24@28216|Betaproteobacteria,3T1BF@506|Alcaligenaceae 28216|Betaproteobacteria Q Ectoine hydroxylase thpD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 ko:K10674 ko00260,ko01120,map00260,map01120 - R08050 RC00661 ko00000,ko00001,ko01000 - - - PhyH DYD2_k127_6653285_31 472759.Nhal_2705 1.277e-105 351.0 COG0834@1|root,COG0834@2|Bacteria,1R26Z@1224|Proteobacteria,1S2TF@1236|Gammaproteobacteria,1X0JI@135613|Chromatiales 135613|Chromatiales ET PFAM Extracellular solute-binding protein, family 3 - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD2_k127_6653285_45 1156919.QWC_30273 2.702e-77 264.0 COG0765@1|root,COG0765@2|Bacteria,1R3X2@1224|Proteobacteria,2W1TR@28216|Betaproteobacteria,3T27W@506|Alcaligenaceae 28216|Betaproteobacteria E ABC transporter permease ehuC - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 DYD2_k127_6653285_37 1392838.AWNM01000071_gene665 5.587e-89 297.0 COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,2VM04@28216|Betaproteobacteria,3T1CU@506|Alcaligenaceae 28216|Betaproteobacteria E ABC-type amino acid transport system permease component ehuD - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 DYD2_k127_6653285_33 1003200.AXXA_29927 9.038e-101 337.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VZPH@28216|Betaproteobacteria,3T3F4@506|Alcaligenaceae 28216|Betaproteobacteria E abc transporter, ATP-binding protein - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran DYD2_k127_6653285_64 748247.AZKH_2796 3.628e-16 89.0 2C5P4@1|root,3310H@2|Bacteria,1N6V1@1224|Proteobacteria,2VVVI@28216|Betaproteobacteria,2KXKC@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD2_k127_6653285_55 1454004.AW11_02848 2.838e-55 197.0 COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria 1224|Proteobacteria P COG1863 Multisubunit Na H antiporter MnhE subunit mnhE - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE DYD2_k127_6653285_62 1454004.AW11_02849 3.225e-30 122.0 COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria 1224|Proteobacteria P Multiple resistance and pH regulation protein F mnhF - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MrpF_PhaF DYD2_k127_6653285_61 1454004.AW11_02850 1.302e-35 142.0 COG1320@1|root,COG1320@2|Bacteria 2|Bacteria P monovalent cation:proton antiporter activity mnhG - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB DYD2_k127_6653285_51 1454004.AW11_02851 1.497e-64 225.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria 1224|Proteobacteria P Na H antiporter, MnhB - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB DYD2_k127_6653285_54 1454004.AW11_02852 8.688e-59 209.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria 1224|Proteobacteria P Na H antiporter, MnhB - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,MnhB DYD2_k127_6653285_59 1454004.AW11_02853 1.483e-44 172.0 COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria 1224|Proteobacteria P COG1006 Multisubunit Na H antiporter, MnhC subunit mnhC - - ko:K05567 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Oxidored_q2 DYD2_k127_6653285_12 1454004.AW11_02854 2.845e-199 632.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2VP1W@28216|Betaproteobacteria 28216|Betaproteobacteria CP Proton-conducting membrane transporter - - - - - - - - - - - - Proton_antipo_M DYD2_k127_6653285_9 1454004.AW11_02855 3.227e-210 668.0 COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2VPQP@28216|Betaproteobacteria 28216|Betaproteobacteria CP Proton-conducting membrane transporter - - - - - - - - - - - - Proton_antipo_M,Proton_antipo_N DYD2_k127_6653285_63 631454.N177_3896 8.638e-20 95.0 2EDYZ@1|root,337TS@2|Bacteria,1N7SA@1224|Proteobacteria,2UNBF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6653285_6 1454004.AW11_02857 4.384e-254 795.0 COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria 1224|Proteobacteria CP formate hydrogenlyase subunit 3 multisubunit Na H antiporter, MnhD subunit nuoL3 - - ko:K05568,ko:K12137 - - - - ko00000,ko01000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M DYD2_k127_6653285_20 1100720.ALKN01000024_gene1422 1.411e-148 480.0 COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2VHEX@28216|Betaproteobacteria,4ABVA@80864|Comamonadaceae 28216|Betaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP DYD2_k127_6653285_47 1038859.AXAU01000008_gene2024 2.933e-72 248.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U4QB@28211|Alphaproteobacteria,3JRDA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD2_k127_6653285_13 1121939.L861_22295 5.297e-195 617.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1XHAV@135619|Oceanospirillales 135619|Oceanospirillales Q PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM DYD2_k127_6655073_13 671143.DAMO_1046 1.101e-12 76.0 COG4747@1|root,COG4747@2|Bacteria,2NR4R@2323|unclassified Bacteria 2|Bacteria S ACT domain protein hom - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 ko:K00003,ko:K00058,ko:K01754,ko:K04767 ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00017,M00018,M00020,M00570 R00220,R00996,R01513,R01773,R01775 RC00031,RC00087,RC00418,RC02600 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3 DYD2_k127_6655073_12 85643.Tmz1t_3357 3.529e-14 82.0 2EDY7@1|root,337T3@2|Bacteria,1RKSZ@1224|Proteobacteria,2VTSJ@28216|Betaproteobacteria,2KWV4@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD2_k127_6655073_11 1089552.KI911559_gene2779 8.309e-15 80.0 28NIR@1|root,2ZBK2@2|Bacteria,1RAAF@1224|Proteobacteria,2U5XR@28211|Alphaproteobacteria,2JU8G@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD2_k127_6655073_8 1122604.JONR01000032_gene66 3.628e-44 166.0 COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,1SU9C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cyclophilin-like - - - ko:K09143 - - - - ko00000 - - - Cyclophil_like DYD2_k127_6655073_10 1458275.AZ34_07370 7.469e-37 149.0 COG0741@1|root,COG0741@2|Bacteria,1RAP3@1224|Proteobacteria,2VQXG@28216|Betaproteobacteria,4ABW3@80864|Comamonadaceae 28216|Betaproteobacteria M PFAM Lytic transglycosylase catalytic - - - - - - - - - - - - SLT DYD2_k127_6655073_14 640511.BC1002_3420 2.322e-08 58.0 2DR41@1|root,33A2I@2|Bacteria,1NJGU@1224|Proteobacteria,2VXUT@28216|Betaproteobacteria,1KAA6@119060|Burkholderiaceae 28216|Betaproteobacteria S Oxidoreductase-like protein, N-terminal - - - - - - - - - - - - Oxidored-like DYD2_k127_6655073_7 522306.CAP2UW1_3069 3.399e-51 188.0 COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,2VU1J@28216|Betaproteobacteria 28216|Betaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD2_k127_6655073_6 1122604.JONR01000045_gene2493 3.675e-60 219.0 2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,1T055@1236|Gammaproteobacteria,1X6SQ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD2_k127_6655073_0 279714.FuraDRAFT_0324 6.637e-313 970.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,2KQ3F@206351|Neisseriales 206351|Neisseriales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU DYD2_k127_6655073_9 1454004.AW11_03543 2.506e-42 162.0 2CDFS@1|root,32RXQ@2|Bacteria,1N09V@1224|Proteobacteria,2VUR5@28216|Betaproteobacteria,1KR01@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2946) - - - - - - - - - - - - DUF2944 DYD2_k127_6655073_3 1380391.JIAS01000011_gene4626 2.864e-99 333.0 COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,2TSDR@28211|Alphaproteobacteria,2JVQ8@204441|Rhodospirillales 204441|Rhodospirillales S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 DYD2_k127_6655073_4 1003200.AXXA_10570 1.014e-95 324.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VN62@28216|Betaproteobacteria,3T73S@506|Alcaligenaceae 28216|Betaproteobacteria E Threonine aldolase - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase DYD2_k127_6655073_1 1121033.AUCF01000012_gene845 2.823e-110 371.0 COG3639@1|root,COG3639@2|Bacteria,1MUD6@1224|Proteobacteria,2TTVG@28211|Alphaproteobacteria,2JQGZ@204441|Rhodospirillales 204441|Rhodospirillales P COG3639 ABC-type phosphate phosphonate transport system, permease component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 DYD2_k127_6655073_2 1121033.AUCF01000012_gene846 1.323e-102 350.0 COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2U1BD@28211|Alphaproteobacteria,2JS09@204441|Rhodospirillales 204441|Rhodospirillales P COG3639 ABC-type phosphate phosphonate transport system, permease component - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 DYD2_k127_6655073_5 1123060.JONP01000005_gene5670 4.917e-83 280.0 COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,2TRR3@28211|Alphaproteobacteria,2JQEH@204441|Rhodospirillales 204441|Rhodospirillales P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system - - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran DYD2_k127_6693118_19 1132855.KB913035_gene1399 1.691e-06 53.0 COG4970@1|root,COG4970@2|Bacteria,1N8HW@1224|Proteobacteria,2VWJK@28216|Betaproteobacteria,2KN45@206350|Nitrosomonadales 206350|Nitrosomonadales NU Tfp pilus assembly protein FimT - - - ko:K10926 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - GspH,N_methyl DYD2_k127_6693118_17 697282.Mettu_3216 2.51e-15 89.0 COG4967@1|root,COG4967@2|Bacteria,1RKKA@1224|Proteobacteria 1224|Proteobacteria NU type IV pilus modification protein PilV - - - ko:K10927 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl DYD2_k127_6693118_15 292415.Tbd_0756 2.898e-19 101.0 COG4967@1|root,COG4967@2|Bacteria,1RKKA@1224|Proteobacteria,2VTQ8@28216|Betaproteobacteria 28216|Betaproteobacteria NU type IV pilus modification protein PilV - - - ko:K10927 ko05111,map05111 - - - ko00000,ko00001,ko02044 - - - N_methyl DYD2_k127_6693118_5 56780.SYN_02946 1.409e-166 539.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MQ56@213462|Syntrophobacterales 28221|Deltaproteobacteria M TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - MFS_1,OEP DYD2_k127_6693118_3 375286.mma_2403 7.222e-264 833.0 COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,472FR@75682|Oxalobacteraceae 28216|Betaproteobacteria M Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,POTRA,Patatin DYD2_k127_6693118_13 85643.Tmz1t_3871 3.818e-34 138.0 COG2067@1|root,COG2067@2|Bacteria,1REWT@1224|Proteobacteria,2VVIS@28216|Betaproteobacteria 28216|Betaproteobacteria I long-chain fatty acid transport protein - - - - - - - - - - - - - DYD2_k127_6693118_18 1049564.TevJSym_at00050 8.457e-12 69.0 COG3637@1|root,COG3637@2|Bacteria,1N7AR@1224|Proteobacteria,1SHEZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - DYD2_k127_6693118_11 215803.DB30_7833 1.812e-36 146.0 COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,43BTI@68525|delta/epsilon subdivisions,2X74F@28221|Deltaproteobacteria,2Z3FS@29|Myxococcales 28221|Deltaproteobacteria M Chalcone isomerase-like - - - - - - - - - - - - Chalcone_3 DYD2_k127_6693118_7 1038860.AXAP01000015_gene2095 3.65e-107 355.0 COG0637@1|root,COG0637@2|Bacteria,1RGJC@1224|Proteobacteria,2UAPW@28211|Alphaproteobacteria 28211|Alphaproteobacteria G TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - - - - - - - - - - HAD_2,Hydrolase DYD2_k127_6693118_1 1038860.AXAP01000015_gene2096 0.0 1011.0 COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,2U1CG@28211|Alphaproteobacteria,3JWWP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Glycosyl hydrolase family 65, C-terminal domain - - 2.4.1.64,5.4.2.6 ko:K01838,ko:K05342 ko00500,ko01100,map00500,map01100 - R02727,R02728,R11310 RC00049,RC00408 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2 DYD2_k127_6693118_0 1038860.AXAP01000015_gene2094 0.0 1450.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2TU2E@28211|Alphaproteobacteria,3JRH2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G aldehyde-lyase activity xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N DYD2_k127_6693118_16 1134474.O59_002857 1.411e-15 82.0 COG3187@1|root,COG3187@2|Bacteria,1N9XV@1224|Proteobacteria,1S4T0@1236|Gammaproteobacteria,1FHK2@10|Cellvibrio 1236|Gammaproteobacteria O META domain - - - ko:K09914 - - - - ko00000 - - - META,NlpE,NlpE_C,YscW DYD2_k127_6693118_14 1298865.H978DRAFT_1975 1.85e-27 119.0 COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S2SV@1236|Gammaproteobacteria,466PQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S Las17-binding protein actin regulator VPA0371 - - - - - - - - - - - Ysc84 DYD2_k127_6693118_4 1122611.KB904018_gene6923 1.3e-233 738.0 COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4EGGJ@85012|Streptosporangiales 201174|Actinobacteria G Glycosyl hydrolases family 15 - - - - - - - - - - - - Glyco_hydro_15 DYD2_k127_6693118_6 1454004.AW11_02083 1.273e-133 430.0 COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2WF0A@28216|Betaproteobacteria 28216|Betaproteobacteria IQ KR domain - - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 DYD2_k127_6693118_9 266835.14022938 5.68e-70 253.0 COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,2TRM3@28211|Alphaproteobacteria,43NJZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin DYD2_k127_6693118_2 522306.CAP2UW1_1285 5.686e-316 986.0 COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2WHVC@28216|Betaproteobacteria 28216|Betaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,Paired_CXXCH_1 DYD2_k127_6693118_8 591167.Sfla_1877 2.416e-95 325.0 COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria 201174|Actinobacteria M 40-residue YVTN family beta-propeller repeat - - - - - - - - - - - - Lactonase DYD2_k127_6693118_12 1463934.JOCF01000096_gene1779 2.503e-36 150.0 COG0631@1|root,COG0631@2|Bacteria,2GMNH@201174|Actinobacteria 201174|Actinobacteria T Serine/threonine phosphatases, family 2C, catalytic domain - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 DYD2_k127_6693118_10 396588.Tgr7_2163 9.455e-41 151.0 COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1SMM0@1236|Gammaproteobacteria,1X258@135613|Chromatiales 135613|Chromatiales P von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - DYD2_k127_6725129_4 913325.N799_09345 2.023e-100 330.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,1X3KR@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase DYD2_k127_6725129_0 1000565.METUNv1_01394 4.355e-320 992.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales 206389|Rhodocyclales C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase DYD2_k127_6725129_1 472759.Nhal_0506 1.209e-205 646.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1WWG7@135613|Chromatiales 135613|Chromatiales G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK DYD2_k127_6725129_5 1255043.TVNIR_3622 3.874e-95 316.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid DYD2_k127_6725129_6 265072.Mfla_2087 2.489e-90 304.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,2KKCN@206350|Nitrosomonadales 206350|Nitrosomonadales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 DYD2_k127_6725129_9 1163617.SCD_n01892 2.493e-23 109.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria 28216|Betaproteobacteria S Belongs to the UPF0434 family ycaR - - ko:K09791 - - - - ko00000 - - - Trm112p DYD2_k127_6725129_3 1485544.JQKP01000001_gene1259 1.383e-101 342.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,44UYT@713636|Nitrosomonadales 28216|Betaproteobacteria M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK DYD2_k127_6725129_8 402626.Rpic_2806 1.036e-42 161.0 COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,1K75Q@119060|Burkholderiaceae 28216|Betaproteobacteria U biopolymer transport exbD2 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD DYD2_k127_6725129_7 1485544.JQKP01000001_gene1261 8.638e-87 290.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,44V9Z@713636|Nitrosomonadales 28216|Betaproteobacteria U PFAM MotA TolQ ExbB proton channel exbB2 - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB DYD2_k127_6725129_2 582744.Msip34_0936 2.566e-108 356.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,2KKEN@206350|Nitrosomonadales 206350|Nitrosomonadales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 DYD2_k127_6747137_6 1208923.CKBE_00160 9.724e-19 85.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2VKUA@28216|Betaproteobacteria,1KPWI@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG DYD2_k127_6747137_3 312153.Pnuc_0042 3.858e-75 253.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2VPZW@28216|Betaproteobacteria,1K762@119060|Burkholderiaceae 28216|Betaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK - - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N DYD2_k127_6747137_2 580332.Slit_0757 6.945e-100 337.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2VHDK@28216|Betaproteobacteria,44VJR@713636|Nitrosomonadales 28216|Betaproteobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA - - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 DYD2_k127_6747137_4 323848.Nmul_A0757 1.138e-72 248.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2VQ7A@28216|Betaproteobacteria,372FE@32003|Nitrosomonadales 28216|Betaproteobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 DYD2_k127_6747137_5 323848.Nmul_A0758 2.203e-50 181.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,373C9@32003|Nitrosomonadales 28216|Betaproteobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N DYD2_k127_6747137_1 1163617.SCD_n00618 0.0 2286.0 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria 28216|Betaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 DYD2_k127_6747137_0 1266925.JHVX01000019_gene1787 0.0 2316.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,371R1@32003|Nitrosomonadales 28216|Betaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 DYD2_k127_695154_1 1163617.SCD_n00085 6.296e-231 728.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria 28216|Betaproteobacteria G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C DYD2_k127_695154_11 1121035.AUCH01000008_gene1018 9.096e-31 123.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,2KWVF@206389|Rhodocyclales 206389|Rhodocyclales G Phosphotransferase System ptsH - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr DYD2_k127_695154_10 1123367.C666_13380 4.366e-50 181.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,2KWTC@206389|Rhodocyclales 206389|Rhodocyclales G Phosphotransferase system, mannose fructose-specific component IIA ptsL - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - EIIA-man DYD2_k127_695154_4 1288494.EBAPG3_5540 1.553e-136 440.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,37249@32003|Nitrosomonadales 28216|Betaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N DYD2_k127_695154_3 1122236.KB905143_gene258 2.073e-198 630.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,2KKII@206350|Nitrosomonadales 206350|Nitrosomonadales P Ammonium Transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp DYD2_k127_695154_9 640081.Dsui_0764 2.778e-57 201.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KWCQ@206389|Rhodocyclales 206389|Rhodocyclales K Belongs to the P(II) protein family glnK - - ko:K04752 - - - - ko00000 - - - P-II DYD2_k127_695154_7 1000565.METUNv1_03322 6.853e-83 288.0 2C5U9@1|root,30FF7@2|Bacteria,1N2U0@1224|Proteobacteria,2VSBN@28216|Betaproteobacteria,2KWHS@206389|Rhodocyclales 206389|Rhodocyclales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp DYD2_k127_695154_12 243365.CV_4001 3.218e-20 94.0 COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,2VVR4@28216|Betaproteobacteria,2KRI8@206351|Neisseriales 206351|Neisseriales S Psort location Cytoplasmic, score 8.96 - - - ko:K09806 - - - - ko00000 - - - BMFP DYD2_k127_695154_2 580332.Slit_0062 2.099e-220 693.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,44V3K@713636|Nitrosomonadales 28216|Betaproteobacteria O Magnesium chelatase, subunit ChlI C-terminal comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C DYD2_k127_695154_5 748247.AZKH_4413 3.372e-114 382.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,2KUCA@206389|Rhodocyclales 206389|Rhodocyclales EGP drug resistance transporter - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 DYD2_k127_695154_6 1123393.KB891330_gene898 3.373e-103 348.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,1KSVB@119069|Hydrogenophilales 119069|Hydrogenophilales S VIT family - - - - - - - - - - - - VIT1 DYD2_k127_695154_8 1163617.SCD_n00224 5.838e-61 212.0 COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria 28216|Betaproteobacteria P rhodanese-related sulfurtransferase - - - - - - - - - - - - Rhodanese DYD2_k127_695154_0 323848.Nmul_A0045 7.331e-283 878.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,372NK@32003|Nitrosomonadales 28216|Betaproteobacteria H Methionine synthase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans DYD2_k127_698941_2 1163617.SCD_n02520 2.553e-173 548.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria 28216|Betaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD2_k127_698941_16 1163617.SCD_n02519 5.487e-56 204.0 28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_698941_19 580332.Slit_2453 4.543e-48 175.0 COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,44WIP@713636|Nitrosomonadales 28216|Betaproteobacteria M Polymer-forming cytoskeletal ccmA - - - - - - - - - - - Bactofilin DYD2_k127_698941_18 1236959.BAMT01000017_gene2343 5.757e-55 195.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,2KMS7@206350|Nitrosomonadales 206350|Nitrosomonadales C Required for insertion of 4Fe-4S clusters erpA - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn DYD2_k127_698941_13 497964.CfE428DRAFT_4114 1.657e-64 231.0 COG1043@1|root,COG1043@2|Bacteria,46SD4@74201|Verrucomicrobia 74201|Verrucomicrobia M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep DYD2_k127_698941_4 1163617.SCD_n02516 6.742e-129 421.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK DYD2_k127_698941_3 1163617.SCD_n02515 4.938e-135 443.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria 28216|Betaproteobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 DYD2_k127_698941_0 1288494.EBAPG3_4680 1.052e-190 602.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,3723P@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,S4_2,tRNA-synt_1b DYD2_k127_698941_6 626887.J057_21455 1.492e-97 331.0 COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,465WT@72275|Alteromonadaceae 1236|Gammaproteobacteria CE Belongs to the selenophosphate synthase 1 family. Class I subfamily - - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C,Pyr_redox_2 DYD2_k127_698941_5 290315.Clim_1228 3.308e-100 346.0 COG1512@1|root,COG1512@2|Bacteria,1FENY@1090|Chlorobi 1090|Chlorobi S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase DYD2_k127_698941_21 517417.Cpar_1206 1.643e-29 127.0 COG3762@1|root,COG3762@2|Bacteria,1FEPE@1090|Chlorobi 1090|Chlorobi S TPM domain - - - - - - - - - - - - TPM_phosphatase DYD2_k127_698941_10 1005048.CFU_0108 3.634e-74 260.0 COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,2VIYU@28216|Betaproteobacteria,474EB@75682|Oxalobacteraceae 28216|Betaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_26,HTH_3 DYD2_k127_698941_22 1286093.C266_02958 2.701e-20 102.0 COG1633@1|root,COG1633@2|Bacteria,1R5XX@1224|Proteobacteria,2WGRU@28216|Betaproteobacteria,1KIHR@119060|Burkholderiaceae 28216|Betaproteobacteria S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - FA_desaturase_2 DYD2_k127_698941_9 1122223.KB890687_gene2436 2.684e-80 271.0 COG0225@1|root,COG0225@2|Bacteria,1WK2Z@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR DYD2_k127_698941_8 929556.Solca_3257 3.112e-90 307.0 COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1IQI3@117747|Sphingobacteriia 976|Bacteroidetes E Asparaginase - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 DYD2_k127_698941_20 1502852.FG94_02389 6.966e-32 128.0 COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2VSPC@28216|Betaproteobacteria,474Q9@75682|Oxalobacteraceae 28216|Betaproteobacteria B SWI complex, BAF60b domains - - - - - - - - - - - - SWIB DYD2_k127_698941_11 338969.Rfer_0960 3.578e-73 264.0 COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria 28216|Betaproteobacteria EGP major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_698941_15 977880.RALTA_A1300 2.043e-56 212.0 COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2VMQB@28216|Betaproteobacteria,1K049@119060|Burkholderiaceae 28216|Betaproteobacteria EG Drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD2_k127_698941_17 1380394.JADL01000002_gene1399 1.347e-55 202.0 COG4094@1|root,COG4094@2|Bacteria,1RDV6@1224|Proteobacteria,2U609@28211|Alphaproteobacteria,2JSHA@204441|Rhodospirillales 204441|Rhodospirillales S NnrU protein - - - - - - - - - - - - NnrU DYD2_k127_698941_7 316067.Geob_0941 3.856e-96 329.0 COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,43TKF@69541|Desulfuromonadales 28221|Deltaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF DYD2_k127_698941_1 1144319.PMI16_04778 3.44e-180 575.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2VHFA@28216|Betaproteobacteria,473ET@75682|Oxalobacteraceae 28216|Betaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim DYD2_k127_698941_12 1128421.JAGA01000002_gene1529 3.271e-71 247.0 COG0259@1|root,COG0259@2|Bacteria,2NQT9@2323|unclassified Bacteria 2|Bacteria H Pfam:PNPOx_C pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - iJN678.pdxH PNP_phzG_C,Putative_PNPOx DYD2_k127_698941_14 1101195.Meth11DRAFT_1787 2.504e-58 213.0 COG4520@1|root,COG4520@2|Bacteria,1RIHU@1224|Proteobacteria,2VTAT@28216|Betaproteobacteria,2KNS8@206350|Nitrosomonadales 206350|Nitrosomonadales M Glycine zipper - - - - - - - - - - - - Rick_17kDa_Anti DYD2_k127_698941_23 1320556.AVBP01000001_gene4691 2.261e-19 96.0 COG3779@1|root,COG3779@2|Bacteria,1R3Q7@1224|Proteobacteria,2UFEG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF2314 DYD2_k127_699199_4 94624.Bpet2244 2.026e-55 204.0 COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,2VRNN@28216|Betaproteobacteria,3T3PN@506|Alcaligenaceae 28216|Betaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR DYD2_k127_699199_2 1121920.AUAU01000012_gene2685 6.325e-61 216.0 COG2095@1|root,COG2095@2|Bacteria 2|Bacteria U MarC family integral membrane protein yhgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD2_k127_699199_5 1537994.JQFW01000049_gene2626 3.832e-05 54.0 2ESM0@1|root,33K5K@2|Bacteria,1N02H@1224|Proteobacteria,1SA2K@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_699199_1 1192034.CAP_3990 1.824e-123 406.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales 28221|Deltaproteobacteria E Threonine dehydratase - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_699199_0 114615.BRADO3160 1.023e-223 713.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,3JRND@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K00256 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_699199_3 1532558.JL39_05950 1.514e-56 201.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U7NJ@28211|Alphaproteobacteria,4BF1Y@82115|Rhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 DYD2_k127_69989_17 1266925.JHVX01000011_gene1531 3.029e-30 128.0 2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria,3734J@32003|Nitrosomonadales 28216|Betaproteobacteria S zinc-ribbon domain - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 DYD2_k127_69989_6 323848.Nmul_A0214 5.946e-132 430.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,372CZ@32003|Nitrosomonadales 28216|Betaproteobacteria H The glycine cleavage system catalyzes the degradation of glycine gcvT GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C DYD2_k127_69989_14 323848.Nmul_A0213 1.076e-51 185.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,373A1@32003|Nitrosomonadales 28216|Betaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H DYD2_k127_69989_3 261292.Nit79A3_1224 3.94e-189 601.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,3720Y@32003|Nitrosomonadales 28216|Betaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P DYD2_k127_69989_9 1479237.JMLY01000001_gene408 5.491e-67 235.0 COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,466K3@72275|Alteromonadaceae 1236|Gammaproteobacteria O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin DYD2_k127_69989_0 323848.Nmul_A0210 3.791e-238 753.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,37240@32003|Nitrosomonadales 28216|Betaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - Aminotran_5,GDC-P DYD2_k127_69989_15 640081.Dsui_0392 2.078e-43 164.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales 206389|Rhodocyclales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid - - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar DYD2_k127_69989_12 265072.Mfla_0647 6.656e-56 201.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,2KN6T@206350|Nitrosomonadales 206350|Nitrosomonadales M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL DYD2_k127_69989_4 1163617.SCD_n02776 2.293e-151 485.0 COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria 28216|Betaproteobacteria G PFAM PfkB domain protein adoK - 2.7.1.15,2.7.1.20 ko:K00852,ko:K00856 ko00030,ko00230,ko01100,map00030,map00230,map01100 - R00185,R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB DYD2_k127_69989_7 323848.Nmul_A0206 3.537e-104 346.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,37243@32003|Nitrosomonadales 28216|Betaproteobacteria T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos DYD2_k127_69989_10 1007105.PT7_2423 1.372e-62 226.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,3T2GI@506|Alcaligenaceae 28216|Betaproteobacteria C COG3245 Cytochrome c5 - - - - - - - - - - - - Cytochrome_CBB3 DYD2_k127_69989_19 1150469.RSPPHO_02782 5.367e-06 48.0 COG3420@1|root,COG3420@2|Bacteria 2|Bacteria P alginic acid biosynthetic process - - - ko:K10297 - - - - ko00000,ko04121 - - - Beta_helix,SLH,TIR_2 DYD2_k127_69989_13 748280.NH8B_3073 5.325e-54 195.0 COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,2KRJ8@206351|Neisseriales 206351|Neisseriales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_69989_1 760117.JN27_07710 4.613e-223 703.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2VRSD@28216|Betaproteobacteria,475NM@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Thi4 family - - - - - - - - - - - - Amino_oxidase,DAO,NAD_binding_8 DYD2_k127_69989_5 1123073.KB899241_gene2287 3.36e-141 458.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X7MH@135614|Xanthomonadales 135614|Xanthomonadales E Glycine cleavage T-protein C-terminal barrel domain - - - - - - - - - - - - GCV_T,GCV_T_C DYD2_k127_69989_2 1123073.KB899241_gene2286 1.909e-222 700.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria,1X5MS@135614|Xanthomonadales 135614|Xanthomonadales Q Oxidoreductase - - - - - - - - - - - - Amino_oxidase DYD2_k127_69989_16 502025.Hoch_6530 4.556e-31 127.0 2CGNA@1|root,3301B@2|Bacteria,1N74P@1224|Proteobacteria,42VID@68525|delta/epsilon subdivisions,2WRHN@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - Yippee-Mis18 DYD2_k127_69989_8 204669.Acid345_1271 4.583e-92 321.0 COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia 204432|Acidobacteriia C TIGRFAM phytoene desaturase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase DYD2_k127_69989_11 1123392.AQWL01000005_gene2888 4.573e-60 222.0 COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,2WEFV@28216|Betaproteobacteria,1KS27@119069|Hydrogenophilales 119069|Hydrogenophilales E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 DYD2_k127_69989_18 1331060.RLDS_01755 3.485e-29 123.0 COG3686@1|root,COG3686@2|Bacteria,1RAEH@1224|Proteobacteria,2U5JJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S MAPEG family MA20_30600 - - - - - - - - - - - MAPEG DYD2_k127_726070_23 196490.AUEZ01000043_gene6927 6.543e-05 49.0 2AF3S@1|root,3152G@2|Bacteria,1PV19@1224|Proteobacteria,2V4HP@28211|Alphaproteobacteria,3K5ND@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_726070_11 123899.JPQP01000017_gene2309 2.633e-80 278.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPJ4@28216|Betaproteobacteria,3T36P@506|Alcaligenaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_726070_13 1122134.KB893650_gene1428 2.48e-63 225.0 COG2128@1|root,COG2128@2|Bacteria,1PC51@1224|Proteobacteria,1RS2U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Carboxymuconolactone decarboxylase - - - - - - - - - - - - CMD DYD2_k127_726070_7 1120983.KB894577_gene3576 2.247e-107 357.0 COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2U1NZ@28211|Alphaproteobacteria,1JQNJ@119043|Rhodobiaceae 28211|Alphaproteobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - 1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95 ko:K00018,ko:K00058,ko:K03778 ko00260,ko00620,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00620,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020,M00346 R00704,R00717,R01388,R01513 RC00031,RC00042,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT DYD2_k127_726070_14 439375.Oant_3576 9.584e-54 200.0 COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TTVF@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - 1.1.1.69 ko:K00046 - - - - ko00000,ko01000 - - - adh_short_C2 DYD2_k127_726070_10 631454.N177_1885 4.653e-85 295.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VFM7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_726070_24 408672.NBCG_04475 0.0006424 50.0 2CJ0Q@1|root,32UT5@2|Bacteria,2IH8Y@201174|Actinobacteria,4DV1S@85009|Propionibacteriales 201174|Actinobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD2_k127_726070_3 631454.N177_1887 2.268e-150 492.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA DYD2_k127_726070_19 1297865.APJD01000049_gene5519 9.803e-41 160.0 2B41E@1|root,31WRS@2|Bacteria,1P8VA@1224|Proteobacteria,2TT81@28211|Alphaproteobacteria,3JUBQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_726070_22 1415630.U771_09925 1.58e-31 131.0 2B41E@1|root,31WRS@2|Bacteria,1P8VA@1224|Proteobacteria,1S1WR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_726070_17 1288494.EBAPG3_580 3.157e-48 177.0 COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria,373E8@32003|Nitrosomonadales 28216|Betaproteobacteria S membrane - - - - - - - - - - - - - DYD2_k127_726070_2 1000565.METUNv1_01169 1.342e-235 740.0 COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2VJEQ@28216|Betaproteobacteria,2KUQ3@206389|Rhodocyclales 206389|Rhodocyclales G BT1 family - - - - - - - - - - - - BT1 DYD2_k127_726070_20 1210884.HG799463_gene10324 2.779e-37 154.0 COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes 203682|Planctomycetes KLT COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 DYD2_k127_726070_16 562970.Btus_3057 8.931e-49 183.0 COG1028@1|root,COG1028@2|Bacteria,1V2AS@1239|Firmicutes,4HG9X@91061|Bacilli,278XU@186823|Alicyclobacillaceae 91061|Bacilli IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_726070_8 935261.JAGL01000025_gene79 1.26e-104 362.0 COG0028@1|root,COG0028@2|Bacteria,1MWC3@1224|Proteobacteria,2TTA2@28211|Alphaproteobacteria,43NQ9@69277|Phyllobacteriaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain MA20_15555 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_726070_1 1123368.AUIS01000013_gene852 2.607e-253 792.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,2NCB0@225057|Acidithiobacillales 1236|Gammaproteobacteria G Protein of unknown function (DUF3417) - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase DYD2_k127_726070_0 1232410.KI421426_gene1372 0.0 1028.0 COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,42Q4Z@68525|delta/epsilon subdivisions,2WM28@28221|Deltaproteobacteria 28221|Deltaproteobacteria G PFAM Glycoside hydrolase family 65, central catalytic - - - - - - - - - - - - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase DYD2_k127_726070_6 323098.Nwi_2641 9.099e-120 396.0 COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,3JR2T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2,5.3.1.9 ko:K01810,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI,TAL_FSA DYD2_k127_726070_4 1187851.A33M_0093 2.549e-141 463.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,3FDTN@34008|Rhodovulum 28211|Alphaproteobacteria G C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM DYD2_k127_726070_21 1187851.A33M_0092 5.066e-36 143.0 COG3090@1|root,COG3090@2|Bacteria,1QYHJ@1224|Proteobacteria,2UI8I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ DYD2_k127_726070_5 1187851.A33M_0090 4.649e-130 426.0 COG1638@1|root,COG1638@2|Bacteria,1PJG1@1224|Proteobacteria,2V8IQ@28211|Alphaproteobacteria,3FEKB@34008|Rhodovulum 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP DYD2_k127_726070_9 1121106.JQKB01000054_gene4464 2.411e-89 301.0 COG1028@1|root,COG1028@2|Bacteria,1MVA5@1224|Proteobacteria,2U2EZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase MA20_21425 - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 DYD2_k127_726070_15 666681.M301_1589 1.863e-53 192.0 COG4969@1|root,COG4969@2|Bacteria,1N4MN@1224|Proteobacteria,2VVHM@28216|Betaproteobacteria,2KNTC@206350|Nitrosomonadales 206350|Nitrosomonadales NU Pilin (bacterial filament) - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD2_k127_726070_18 1217720.ALOX01000047_gene1362 9.441e-42 162.0 COG1028@1|root,COG1028@2|Bacteria,1MU73@1224|Proteobacteria,2TV6T@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase SDR - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_726070_12 977880.RALTA_B1898 1.034e-71 254.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP82@28216|Betaproteobacteria,1KD4A@119060|Burkholderiaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_747915_3 265072.Mfla_2142 4.082e-187 594.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,2KKCS@206350|Nitrosomonadales 206350|Nitrosomonadales NU PFAM type II secretion system - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF DYD2_k127_747915_4 323848.Nmul_A2132 8.359e-159 511.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria,372CM@32003|Nitrosomonadales 28216|Betaproteobacteria P Domain of unknown function DUF21 corB - - - - - - - - - - - CBS,CorC_HlyC,DUF21 DYD2_k127_747915_11 323848.Nmul_A2133 2.527e-97 326.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,371QS@32003|Nitrosomonadales 28216|Betaproteobacteria S PFAM Cytochrome c assembly protein ypjD - - - - - - - - - - - Cytochrom_C_asm DYD2_k127_747915_2 1123367.C666_04885 3.364e-208 662.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,2KUVT@206389|Rhodocyclales 206389|Rhodocyclales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB DYD2_k127_747915_10 794903.OPIT5_26535 1.539e-100 335.0 COG0778@1|root,COG0778@2|Bacteria,46YQM@74201|Verrucomicrobia,3KA08@414999|Opitutae 414999|Opitutae C Nitroreductase family - - 1.5.1.39 ko:K19286 ko00740,ko01100,map00740,map01100 - R05705,R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase DYD2_k127_747915_22 266264.Rmet_0748 1.577e-30 126.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,1K8BW@119060|Burkholderiaceae 28216|Betaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 DYD2_k127_747915_16 1163617.SCD_n02460 3.199e-51 189.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria 28216|Betaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM DYD2_k127_747915_9 1163617.SCD_n02459 6.103e-108 357.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria 28216|Betaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT DYD2_k127_747915_15 261292.Nit79A3_0562 5.604e-56 199.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,3735N@32003|Nitrosomonadales 28216|Betaproteobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 DYD2_k127_747915_21 204773.HEAR3336 3.071e-34 144.0 COG2721@1|root,COG2721@2|Bacteria,1MZBN@1224|Proteobacteria,2VU0R@28216|Betaproteobacteria 28216|Betaproteobacteria G SAF - - 4.4.1.24 ko:K16845 ko00270,map00270 - R07633 RC01785 ko00000,ko00001,ko01000 - - - SAF DYD2_k127_747915_1 543728.Vapar_3819 2.185e-211 661.0 COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VK3Y@28216|Betaproteobacteria,4AGID@80864|Comamonadaceae 28216|Betaproteobacteria G PFAM D-galactarate dehydratase Altronate hydrolase domain protein - - 4.4.1.24 ko:K16846 ko00270,map00270 - R07633 RC01785 ko00000,ko00001,ko01000 - - - GD_AH_C DYD2_k127_747915_8 713586.KB900536_gene710 6.47e-112 367.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales 1236|Gammaproteobacteria C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - - - - - - - - - - Fer2_3,Fer4_17,Fer4_8 DYD2_k127_747915_23 1121861.KB899918_gene3220 3.099e-30 123.0 COG2142@1|root,COG2142@2|Bacteria,1MZKE@1224|Proteobacteria,2UDDU@28211|Alphaproteobacteria,2JY8A@204441|Rhodospirillales 204441|Rhodospirillales C Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - - - - - - - - - - Sdh_cyt DYD2_k127_747915_19 1380394.JADL01000014_gene197 1.669e-40 156.0 COG2009@1|root,COG2009@2|Bacteria,1N8VA@1224|Proteobacteria,2UAYI@28211|Alphaproteobacteria,2JXUG@204441|Rhodospirillales 204441|Rhodospirillales C Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - - - - - - - - - - Sdh_cyt DYD2_k127_747915_20 477974.Daud_1309 2.226e-34 143.0 COG1809@1|root,COG1809@2|Bacteria,1V20V@1239|Firmicutes,24EBV@186801|Clostridia,261DV@186807|Peptococcaceae 186801|Clostridia S PFAM (2R)-phospho-3-sulfolactate synthase ComA comA - 4.4.1.19 ko:K08097 ko00680,ko01120,map00680,map01120 M00358 R07476 RC01799 ko00000,ko00001,ko00002,ko01000 - - - ComA DYD2_k127_747915_6 344747.PM8797T_15706 7.445e-118 394.0 COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A and related enzymes - - - - - - - - - - - - DUF4976,Sulfatase DYD2_k127_747915_5 1504672.669784588 1.399e-145 465.0 COG1951@1|root,COG1951@2|Bacteria,1MW8J@1224|Proteobacteria,2VNF1@28216|Betaproteobacteria,4AF2N@80864|Comamonadaceae 28216|Betaproteobacteria C Fe-S type, tartrate fumarate subfamily, alpha subunit - - 4.2.1.32 ko:K03779 ko00630,map00630 - R00339 RC01382 ko00000,ko00001,ko01000 - - - Fumerase DYD2_k127_747915_12 795666.MW7_3398 5.48e-92 318.0 COG1838@1|root,COG1838@2|Bacteria,1MVNG@1224|Proteobacteria,2VMDH@28216|Betaproteobacteria,1K6CN@119060|Burkholderiaceae 28216|Betaproteobacteria C Fumarase C-terminus - - 4.2.1.2,4.2.1.32 ko:K01678,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00339,R01082 RC00443,RC01382 ko00000,ko00001,ko00002,ko01000 - - - Fumerase_C DYD2_k127_747915_0 667632.KB890209_gene5474 2.068e-272 849.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VI6D@28216|Betaproteobacteria,1K5TM@119060|Burkholderiaceae 28216|Betaproteobacteria C Fumarate reductase flavoprotein C-term - - 1.3.5.1,1.3.5.4 ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD2_k127_747915_7 713586.KB900536_gene702 1.049e-112 373.0 COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,1RRSU@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the LDH2 MDH2 oxidoreductase family comC - 1.1.1.338,1.5.1.21 ko:K13609,ko:K16844 ko00270,ko00310,ko00960,ko01100,ko01120,map00270,map00310,map00960,map01100,map01120 - R02203,R07137 RC00031,RC00135 ko00000,ko00001,ko01000 - - - Ldh_2 DYD2_k127_747915_18 365046.Rta_05720 2.882e-41 168.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,4AB39@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM acyl-CoA dehydrogenase domain protein - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_747915_17 1120972.AUMH01000033_gene3067 5.194e-46 181.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,277WW@186823|Alicyclobacillaceae 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain acdA - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_747915_26 1123252.ATZF01000022_gene3005 0.0007388 49.0 COG2140@1|root,COG2140@2|Bacteria,1TPC2@1239|Firmicutes,4HA6V@91061|Bacilli,27CQK@186824|Thermoactinomycetaceae 91061|Bacilli G Cupin oxdD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0033609,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046564,GO:0071704 4.1.1.2 ko:K01569 ko00630,ko01100,map00630,map01100 - R00522 RC00321 ko00000,ko00001,ko01000 - - iYO844.BSU18670 Cupin_1 DYD2_k127_747915_13 1120999.JONM01000002_gene950 1.4e-88 302.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VIVP@28216|Betaproteobacteria,2KTRA@206351|Neisseriales 206351|Neisseriales CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C DYD2_k127_747915_14 358220.C380_21385 1.603e-75 262.0 COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VM00@28216|Betaproteobacteria,4ABHF@80864|Comamonadaceae 28216|Betaproteobacteria S Ankyrin repeats (3 copies) - - - ko:K06867 - - - - ko00000 - - - Ank_2,Ank_4 DYD2_k127_747915_25 391593.RCCS2_02098 9.682e-08 56.0 2DWFS@1|root,32V1J@2|Bacteria,1MZ9A@1224|Proteobacteria,2UDME@28211|Alphaproteobacteria,2P403@2433|Roseobacter 28211|Alphaproteobacteria S Nitrile hydratase beta subunit - - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta DYD2_k127_837395_0 1205680.CAKO01000002_gene2549 1.156e-83 285.0 COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM amidohydrolase 2 - - - - - - - - - - - - Amidohydro_2 DYD2_k127_837395_3 2074.JNYD01000004_gene4755 1.156e-55 203.0 COG0596@1|root,COG0596@2|Bacteria,2IAKH@201174|Actinobacteria,4E9MU@85010|Pseudonocardiales 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD2_k127_837395_2 1231057.AMGD01000074_gene2078 7.289e-56 215.0 COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli,26GSU@186818|Planococcaceae 91061|Bacilli S Amidohydrolase - - 4.1.1.45,4.1.1.52 ko:K03392,ko:K22213 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD2_k127_837395_1 1040989.AWZU01000013_gene1643 6.021e-74 260.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3JV1H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC DYD2_k127_837395_4 1254432.SCE1572_23905 1.588e-43 162.0 COG0346@1|root,COG0346@2|Bacteria,1RI3Q@1224|Proteobacteria,43DXJ@68525|delta/epsilon subdivisions,2WZ51@28221|Deltaproteobacteria,2Z1CE@29|Myxococcales 28221|Deltaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - - DYD2_k127_849613_4 472759.Nhal_3514 2.794e-94 316.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWG5@135613|Chromatiales 135613|Chromatiales V pfam abc - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_849613_0 582744.Msip34_1525 1.007e-175 557.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VIK6@28216|Betaproteobacteria,2KMCY@206350|Nitrosomonadales 206350|Nitrosomonadales S TIGRFAM coenzyme PQQ biosynthesis protein E pqqE - - ko:K06139 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM DYD2_k127_849613_7 595537.Varpa_0711 1.1e-26 113.0 2E4CK@1|root,32Z81@2|Bacteria,1N7JR@1224|Proteobacteria,2VVSC@28216|Betaproteobacteria,4AG0T@80864|Comamonadaceae 28216|Betaproteobacteria S PFAM coenzyme PQQ synthesis D pqqD - - ko:K06138 - - - - ko00000 - - - PqqD DYD2_k127_849613_3 395493.BegalDRAFT_0319 3.439e-122 396.0 COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,1RP1V@1236|Gammaproteobacteria,461R8@72273|Thiotrichales 72273|Thiotrichales H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ pqqC - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - TENA_THI-4 DYD2_k127_849613_2 582744.Msip34_1528 2.201e-130 422.0 COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,2VJUF@28216|Betaproteobacteria,2KM3R@206350|Nitrosomonadales 206350|Nitrosomonadales S May be involved in the transport of PQQ or its precursor to the periplasm pqqB - - ko:K06136 - - - - ko00000 - - - Lactamase_B_2 DYD2_k127_849613_5 1207063.P24_07151 1.425e-83 289.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2TS53@28211|Alphaproteobacteria,2JYWX@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the peptidase S33 family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 DYD2_k127_849613_1 1097668.BYI23_C002800 7.762e-135 446.0 COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2VISJ@28216|Betaproteobacteria,1K1U6@119060|Burkholderiaceae 28216|Betaproteobacteria CH salicylate hydroxylase mhbM - 1.14.13.1,1.14.13.24 ko:K00480,ko:K22270 ko00362,ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00362,map00621,map00624,map00626,map01100,map01120,map01220 - R00818,R02589,R05632,R06915,R06936,R06939 RC00046,RC00389 ko00000,ko00001,ko01000 - - - FAD_binding_3 DYD2_k127_849613_6 795666.MW7_2535 1.801e-33 132.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VHZV@28216|Betaproteobacteria,1KGJP@119060|Burkholderiaceae 28216|Betaproteobacteria C Dehydrogenase - - 1.1.99.31 ko:K15054 ko00627,ko01120,map00627,map01120 - R04160,R07664 RC00240 ko00000,ko00001,ko01000 - - - FMN_dh DYD2_k127_851798_9 196490.AUEZ01000001_gene7327 2.438e-96 323.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,3JSFK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_851798_8 1187851.A33M_3788 3.792e-119 389.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_851798_1 1187851.A33M_0952 2.518e-197 621.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - - - - - - - - - - HMGL-like DYD2_k127_851798_7 1198232.CYCME_2222 6.144e-123 404.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,460KK@72273|Thiotrichales 72273|Thiotrichales P Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD2_k127_851798_4 267608.RSc1799 3.515e-153 494.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,2VPEK@28216|Betaproteobacteria,1K0K3@119060|Burkholderiaceae 28216|Betaproteobacteria C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD2_k127_851798_5 748247.AZKH_3301 4.593e-147 471.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,2KU6K@206389|Rhodocyclales 206389|Rhodocyclales C Transketolase, pyrimidine binding domain - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD2_k127_851798_6 1235457.C404_10290 4.253e-137 444.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VNZH@28216|Betaproteobacteria,1K12G@119060|Burkholderiaceae 28216|Betaproteobacteria C e1 component (alpha subunit) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD2_k127_851798_3 1380394.JADL01000004_gene5718 6.762e-163 520.0 COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TT8C@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase DYD2_k127_851798_10 1123392.AQWL01000001_gene1361 2.886e-34 143.0 COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,2VX2X@28216|Betaproteobacteria,1KS9C@119069|Hydrogenophilales 119069|Hydrogenophilales O Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2 DYD2_k127_851798_0 1163617.SCD_n01489 9.786e-239 752.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria 28216|Betaproteobacteria S 2-methylcitrate dehydratase prpD - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD DYD2_k127_851798_2 1366050.N234_11040 6.476e-193 609.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VHJZ@28216|Betaproteobacteria,1K1TX@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the citrate synthase family prpC - 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - - Citrate_synt DYD2_k127_876663_13 1000565.METUNv1_04051 1.082e-94 316.0 COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,2KV23@206389|Rhodocyclales 206389|Rhodocyclales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ DYD2_k127_876663_6 85643.Tmz1t_2450 1.206e-154 494.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM DYD2_k127_876663_21 85643.Tmz1t_3714 5.227e-34 137.0 COG0746@1|root,COG0746@2|Bacteria,1NBH1@1224|Proteobacteria,2WFP1@28216|Betaproteobacteria,2KXTC@206389|Rhodocyclales 206389|Rhodocyclales H Protein of unknown function (DUF3305) - - - - - - - - - - - - DUF3305 DYD2_k127_876663_28 748247.AZKH_0071 5.452e-15 82.0 2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,2VWJH@28216|Betaproteobacteria,2KXB6@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF3306) - - - - - - - - - - - - DUF3306 DYD2_k127_876663_3 375286.mma_1973 1.786e-230 733.0 COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,472MV@75682|Oxalobacteraceae 28216|Betaproteobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4,Fer4_4,Fer4_6,Fer4_7 DYD2_k127_876663_22 1276756.AUEX01000001_gene1065 4.524e-32 133.0 COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2VJ39@28216|Betaproteobacteria,4ACXM@80864|Comamonadaceae 28216|Betaproteobacteria S cytoplasmic chaperone TorD family protein torD - - - - - - - - - - - Nitrate_red_del DYD2_k127_876663_1 1276756.AUEX01000001_gene1063 0.0 1457.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,4ACV8@80864|Comamonadaceae 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding DYD2_k127_876663_8 1000565.METUNv1_04059 2.375e-124 399.0 COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,2KVJA@206389|Rhodocyclales 206389|Rhodocyclales C 4Fe-4S ferredoxin, iron-sulfur binding - - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Fer4_7 DYD2_k127_876663_27 85643.Tmz1t_3707 3.185e-16 87.0 2E8DM@1|root,332S3@2|Bacteria,1ND1I@1224|Proteobacteria,2VX0K@28216|Betaproteobacteria,2KX9Z@206389|Rhodocyclales 206389|Rhodocyclales - - - - - - - - - - - - - - - DYD2_k127_876663_11 1485544.JQKP01000014_gene1869 1.553e-103 347.0 COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,2VJX1@28216|Betaproteobacteria,44VIP@713636|Nitrosomonadales 28216|Betaproteobacteria H UbiA prenyltransferase family menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD2_k127_876663_2 1123073.KB899241_gene3301 2.968e-244 762.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1X3DC@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the reversible hydration of fumarate to (S)- malate fumB - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C DYD2_k127_876663_4 582744.Msip34_2332 9.452e-167 534.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,2KKRZ@206350|Nitrosomonadales 206350|Nitrosomonadales H PFAM MoeA domain protein domain I and II - - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N DYD2_k127_876663_16 399739.Pmen_0386 3.46e-77 271.0 COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,1RS4Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG2005 N-terminal domain of molybdenum-binding protein - - - - - - - - - - - - HTH_1,HTH_17,PBP_like DYD2_k127_876663_12 472759.Nhal_0511 5.382e-97 321.0 COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,1RYSQ@1236|Gammaproteobacteria,1X2G9@135613|Chromatiales 135613|Chromatiales P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 DYD2_k127_876663_15 1244869.H261_13154 8.505e-84 284.0 COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2TSCU@28211|Alphaproteobacteria,2JRVW@204441|Rhodospirillales 204441|Rhodospirillales E ABC transporter - - - - - - - - - - - - ABC_tran DYD2_k127_876663_7 1000565.METUNv1_01232 1.191e-124 410.0 COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2VJQG@28216|Betaproteobacteria,2KUXA@206389|Rhodocyclales 206389|Rhodocyclales H Bacterial extracellular solute-binding protein - - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 DYD2_k127_876663_26 439375.Oant_3365 2.097e-18 88.0 COG3585@1|root,COG3585@2|Bacteria,1N7IB@1224|Proteobacteria,2UFW3@28211|Alphaproteobacteria 28211|Alphaproteobacteria H PFAM TOBE domain protein - - - - - - - - - - - - TOBE DYD2_k127_876663_10 375286.mma_0186 5.855e-108 363.0 COG0659@1|root,COG0659@2|Bacteria,1MX1U@1224|Proteobacteria,2VZDC@28216|Betaproteobacteria,472VJ@75682|Oxalobacteraceae 28216|Betaproteobacteria P Molybdate transporter of MFS superfamily - - - - - - - - - - - - MFS_MOT1 DYD2_k127_876663_24 375286.mma_3664 2.273e-27 115.0 COG2005@1|root,COG2005@2|Bacteria,1P9SX@1224|Proteobacteria,2VT3R@28216|Betaproteobacteria,478PP@75682|Oxalobacteraceae 28216|Betaproteobacteria S Bacterial regulatory helix-turn-helix protein, lysR family modE2 - - ko:K02019 - - - - ko00000,ko03000 - - - HTH_1 DYD2_k127_876663_17 1267005.KB911259_gene4003 3.076e-73 255.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria,3N7DV@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria P ABC transporter, periplasmic molybdate-binding protein modA GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 DYD2_k127_876663_14 1267005.KB911257_gene641 3.489e-87 293.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria,3N77F@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria P ABC transporter modB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 DYD2_k127_876663_9 1207063.P24_17082 9.448e-110 371.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,2JQNZ@204441|Rhodospirillales 204441|Rhodospirillales P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE DYD2_k127_876663_19 1163617.SCD_n01274 4.601e-64 224.0 COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria 28216|Betaproteobacteria H molybdopterin-guanine dinucleotide biosynthesis protein mobB - - ko:K03753 - - - - ko00000 - - - MobB DYD2_k127_876663_25 1163617.SCD_n01272 2.393e-23 102.0 COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria 28216|Betaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD2_k127_876663_18 1454004.AW11_00359 7.938e-66 227.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,1KQQA@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria H MoaE protein moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE DYD2_k127_876663_20 1163409.UUA_00840 3.119e-42 158.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S9GR@1236|Gammaproteobacteria,1X7EW@135614|Xanthomonadales 135614|Xanthomonadales D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB DYD2_k127_876663_23 765911.Thivi_2528 2.471e-29 119.0 COG1993@1|root,COG1993@2|Bacteria,1RH30@1224|Proteobacteria,1S7XN@1236|Gammaproteobacteria,1WYP4@135613|Chromatiales 135613|Chromatiales S Uncharacterized ACR, COG1993 - - - - - - - - - - - - DUF190 DYD2_k127_876663_5 1163617.SCD_n01463 3.68e-157 511.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria 28216|Betaproteobacteria H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136 ko:K17758 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD2_k127_876663_0 1163617.SCD_n01470 0.0 1836.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria 28216|Betaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 DYD2_k127_884399_0 640081.Dsui_0339 2.91e-113 381.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,2KVBF@206389|Rhodocyclales 206389|Rhodocyclales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY DYD2_k127_884399_6 580332.Slit_0786 9.917e-56 199.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,44VVB@713636|Nitrosomonadales 28216|Betaproteobacteria J Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A DYD2_k127_884399_11 580332.Slit_0785 1.603e-20 94.0 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,44W34@713636|Nitrosomonadales 28216|Betaproteobacteria J Ribosomal protein L30p/L7e rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 DYD2_k127_884399_2 323848.Nmul_A0784 4.105e-83 280.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,3723A@32003|Nitrosomonadales 28216|Betaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C DYD2_k127_884399_9 265072.Mfla_0295 4.805e-40 155.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,2KN1W@206350|Nitrosomonadales 206350|Nitrosomonadales J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p DYD2_k127_884399_3 748247.AZKH_3984 1.651e-74 254.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,2KW6K@206389|Rhodocyclales 206389|Rhodocyclales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 DYD2_k127_884399_5 1266925.JHVX01000018_gene1809 1.953e-58 205.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,373A5@32003|Nitrosomonadales 28216|Betaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 DYD2_k127_884399_8 1288494.EBAPG3_29930 3.948e-40 150.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,373HJ@32003|Nitrosomonadales 28216|Betaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 DYD2_k127_884399_1 323848.Nmul_A0779 1.461e-88 298.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,372JB@32003|Nitrosomonadales 28216|Betaproteobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C DYD2_k127_884399_7 159087.Daro_0330 4.022e-43 172.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,2KWPF@206389|Rhodocyclales 206389|Rhodocyclales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 DYD2_k127_884399_4 395495.Lcho_3939 1.563e-65 226.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2VR2N@28216|Betaproteobacteria,1KM02@119065|unclassified Burkholderiales 28216|Betaproteobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN - - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 DYD2_k127_884399_10 62928.azo3408 1.805e-26 111.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,2KX1P@206389|Rhodocyclales 206389|Rhodocyclales J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 DYD2_k127_903609_1 265072.Mfla_0067 5.36e-225 703.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,2KKNG@206350|Nitrosomonadales 206350|Nitrosomonadales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N,IF2_assoc DYD2_k127_903609_7 713586.KB900536_gene3061 1.059e-40 155.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales 135613|Chromatiales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA DYD2_k127_903609_2 580332.Slit_1484 1.663e-88 303.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,44UZ4@713636|Nitrosomonadales 28216|Betaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N DYD2_k127_903609_8 323848.Nmul_A2554 3.744e-36 138.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,373G3@32003|Nitrosomonadales 28216|Betaproteobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 DYD2_k127_903609_0 1288494.EBAPG3_30600 0.0 1059.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,372MQ@32003|Nitrosomonadales 28216|Betaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 DYD2_k127_903609_4 1288494.EBAPG3_30610 2.331e-66 228.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VRPJ@28216|Betaproteobacteria,3731B@32003|Nitrosomonadales 28216|Betaproteobacteria T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR DYD2_k127_903609_11 748280.NH8B_1148 1.52e-07 55.0 2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD2_k127_903609_3 1123487.KB892843_gene799 1.203e-66 230.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,2KWDY@206389|Rhodocyclales 206389|Rhodocyclales J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB DYD2_k127_903609_6 748247.AZKH_1844 4.414e-53 191.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,2KW7M@206389|Rhodocyclales 206389|Rhodocyclales I Oligoketide cyclase lipid transport protein - - - - - - - - - - - - Polyketide_cyc DYD2_k127_903609_9 754476.Q7A_2179 3.052e-21 98.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,4614M@72273|Thiotrichales 72273|Thiotrichales S Belongs to the UPF0125 (RnfH) family - - - ko:K09801 - - - - ko00000 - - - Ub-RnfH DYD2_k127_903609_10 1454004.AW11_01180 1.42e-12 75.0 2BCK1@1|root,32662@2|Bacteria,1RHH4@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 DYD2_k127_903609_5 159087.Daro_2338 2.602e-56 200.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,2KVFJ@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH DYD2_k127_940980_3 1288494.EBAPG3_23410 5.809e-311 970.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,37235@32003|Nitrosomonadales 28216|Betaproteobacteria M PFAM glycosyl transferase, family 51 mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase DYD2_k127_940980_29 1163617.SCD_n02941 8.48e-153 490.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria 28216|Betaproteobacteria NU Type IV pilus assembly protein PilM pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 DYD2_k127_940980_52 1123392.AQWL01000002_gene1955 1.818e-53 196.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria,1KSSZ@119069|Hydrogenophilales 119069|Hydrogenophilales NU Fimbrial assembly protein (PilN) - - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN DYD2_k127_940980_45 1163617.SCD_n02943 4.346e-74 255.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria 28216|Betaproteobacteria NU Pilus assembly protein, PilO pilO - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO DYD2_k127_940980_59 1163617.SCD_n02944 7.182e-46 171.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,2VSVR@28216|Betaproteobacteria 28216|Betaproteobacteria NU pilus assembly protein PilP pilP - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP DYD2_k127_940980_8 1163617.SCD_n02945 4.218e-266 836.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria 28216|Betaproteobacteria U type IV pilus secretin PilQ pilQ - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N DYD2_k127_940980_51 381666.H16_A3435 9.647e-57 203.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria,1K1DP@119060|Burkholderiaceae 28216|Betaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI DYD2_k127_940980_30 1348657.M622_00025 1.177e-149 481.0 COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,2KURZ@206389|Rhodocyclales 206389|Rhodocyclales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase DYD2_k127_940980_23 1163617.SCD_n02948 6.113e-169 539.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria 28216|Betaproteobacteria F Belongs to the dGTPase family. Type 2 subfamily dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc DYD2_k127_940980_0 1005048.CFU_0502 0.0 2307.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,4723Z@75682|Oxalobacteraceae 28216|Betaproteobacteria E GXGXG motif gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase DYD2_k127_940980_10 1286093.C266_22143 4.317e-242 760.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,1K273@119060|Burkholderiaceae 28216|Betaproteobacteria C glutamate synthase gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 DYD2_k127_940980_28 261292.Nit79A3_1143 3.702e-164 522.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,372TZ@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D DYD2_k127_940980_13 1131553.JIBI01000006_gene1092 1.875e-225 721.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,372GD@32003|Nitrosomonadales 28216|Betaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII DYD2_k127_940980_12 1288494.EBAPG3_27770 6.782e-238 750.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,371R0@32003|Nitrosomonadales 28216|Betaproteobacteria J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d DYD2_k127_940980_57 1288494.EBAPG3_27760 1.713e-46 174.0 COG3087@1|root,COG3087@2|Bacteria,1RIU5@1224|Proteobacteria,2VTKT@28216|Betaproteobacteria,3731K@32003|Nitrosomonadales 28216|Betaproteobacteria D Sporulation related domain - - - - - - - - - - - - SPOR DYD2_k127_940980_48 1266925.JHVX01000005_gene1838 1.473e-62 224.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,372F6@32003|Nitrosomonadales 28216|Betaproteobacteria O Thiol disulfide interchange protein dsbA - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 DYD2_k127_940980_60 1265502.KB905937_gene2589 3.844e-44 169.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,4ADS0@80864|Comamonadaceae 28216|Betaproteobacteria O Thiol disulfide interchange protein dsbA - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin DYD2_k127_940980_42 1266925.JHVX01000005_gene1837 2.767e-95 322.0 COG0300@1|root,COG0300@2|Bacteria,1PNDU@1224|Proteobacteria,2VIWD@28216|Betaproteobacteria,372WG@32003|Nitrosomonadales 28216|Betaproteobacteria S KR domain wcbP - - - - - - - - - - - adh_short DYD2_k127_940980_7 640081.Dsui_1101 1.128e-267 836.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,2KVCK@206389|Rhodocyclales 206389|Rhodocyclales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS DYD2_k127_940980_20 1095769.CAHF01000005_gene1443 1.193e-179 573.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,472BG@75682|Oxalobacteraceae 28216|Betaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3 DYD2_k127_940980_27 1101191.KI912577_gene3113 1.843e-164 531.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,1JRVG@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C DYD2_k127_940980_55 987059.RBXJA2T_16912 2.819e-51 187.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KKT3@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N DYD2_k127_940980_9 381666.H16_A3637 1.277e-265 822.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,1K2Y1@119060|Burkholderiaceae 28216|Betaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N DYD2_k127_940980_34 261292.Nit79A3_0372 2.474e-126 409.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,371MG@32003|Nitrosomonadales 28216|Betaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt DYD2_k127_940980_6 667632.KB890176_gene4611 2.655e-274 850.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,1K1JD@119060|Burkholderiaceae 28216|Betaproteobacteria F Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N DYD2_k127_940980_61 323848.Nmul_A0307 1.139e-41 159.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,3737S@32003|Nitrosomonadales 28216|Betaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP DYD2_k127_940980_56 1266925.JHVX01000005_gene1935 8.488e-50 182.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,372ZX@32003|Nitrosomonadales 28216|Betaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B DYD2_k127_940980_64 323848.Nmul_A0305 3.962e-37 141.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,373AG@32003|Nitrosomonadales 28216|Betaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C DYD2_k127_940980_36 265072.Mfla_2750 1.601e-122 397.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,2KKB3@206350|Nitrosomonadales 206350|Nitrosomonadales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A DYD2_k127_940980_69 1387312.BAUS01000004_gene1492 0.0009013 48.0 2927S@1|root,2ZPSE@2|Bacteria,1NPN8@1224|Proteobacteria,2VZ0K@28216|Betaproteobacteria,2KN6W@206350|Nitrosomonadales 206350|Nitrosomonadales S ATP synthase I chain - - - - - - - - - - - - ATP-synt_I DYD2_k127_940980_43 1288494.EBAPG3_8050 1.864e-93 314.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,3726M@32003|Nitrosomonadales 28216|Betaproteobacteria K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc DYD2_k127_940980_35 1266925.JHVX01000008_gene372 3.076e-125 405.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,371Z8@32003|Nitrosomonadales 28216|Betaproteobacteria D PFAM Cobyrinic acid a,c-diamide synthase parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD2_k127_940980_47 292415.Tbd_2807 9.628e-63 222.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,1KRP8@119069|Hydrogenophilales 119069|Hydrogenophilales J rRNA small subunit methyltransferase G - - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB DYD2_k127_940980_4 1485544.JQKP01000012_gene2172 4.615e-305 945.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,44V4F@713636|Nitrosomonadales 28216|Betaproteobacteria D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc DYD2_k127_940980_26 228410.NE0386 1.922e-165 531.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,371N2@32003|Nitrosomonadales 28216|Betaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N DYD2_k127_940980_15 1288494.EBAPG3_8000 7.426e-212 672.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,371S5@32003|Nitrosomonadales 28216|Betaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas DYD2_k127_940980_68 264198.Reut_A3462 2.638e-15 81.0 COG0594@1|root,COG0594@2|Bacteria,1PVTI@1224|Proteobacteria,2VW57@28216|Betaproteobacteria,1K0Q8@119060|Burkholderiaceae 28216|Betaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P DYD2_k127_940980_67 94624.Bpet5014 1.769e-15 77.0 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria,3T4QS@506|Alcaligenaceae 28216|Betaproteobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 DYD2_k127_940980_19 1288494.EBAPG3_7970 4.624e-193 619.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,372M3@32003|Nitrosomonadales 28216|Betaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N DYD2_k127_940980_31 1266925.JHVX01000008_gene366 1.23e-149 481.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,371UF@32003|Nitrosomonadales 28216|Betaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 DYD2_k127_940980_1 1288494.EBAPG3_7950 0.0 1195.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,3725J@32003|Nitrosomonadales 28216|Betaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD2_k127_940980_2 395019.Bmul_3127 0.0 1084.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1K0Y7@119060|Burkholderiaceae 28216|Betaproteobacteria L dna topoisomerase III topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - SWIB,Topoisom_bac,Toprim,Toprim_Crpt DYD2_k127_940980_37 1163617.SCD_n00007 2.958e-121 399.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria 28216|Betaproteobacteria LU DNA protecting protein DprA smf - - ko:K04096 - - - - ko00000 - - - DNA_processg_A DYD2_k127_940980_44 1163617.SCD_n00008 1.349e-92 319.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM Peptidoglycan-binding LysM - - - - - - - - - - - - LysM DYD2_k127_940980_46 1123393.KB891332_gene2764 1.086e-71 246.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,1KRYP@119069|Hydrogenophilales 119069|Hydrogenophilales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD2_k127_940980_39 748280.NH8B_0285 1.29e-100 337.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,2KPK1@206351|Neisseriales 206351|Neisseriales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD2_k127_940980_32 1163617.SCD_n00011 1.63e-148 483.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria 28216|Betaproteobacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,NusB DYD2_k127_940980_62 395494.Galf_0025 5.884e-40 163.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,44VWB@713636|Nitrosomonadales 28216|Betaproteobacteria S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 DYD2_k127_940980_11 1163617.SCD_n00013 8.292e-239 761.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase ntrY - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8 DYD2_k127_940980_24 1131553.JIBI01000036_gene2049 1.607e-168 539.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,3721F@32003|Nitrosomonadales 28216|Betaproteobacteria T Sigma-54 interaction domain ntrX - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activ_2 DYD2_k127_940980_5 323848.Nmul_A0388 2.265e-294 916.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,372XV@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N DYD2_k127_940980_21 795666.MW7_3562 5.481e-173 548.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,1K1MS@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD2_k127_940980_22 196367.JNFG01000017_gene4170 2.417e-169 539.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,1K22I@119060|Burkholderiaceae 28216|Betaproteobacteria G Belongs to the phosphoglycerate kinase family pgk GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK DYD2_k127_940980_17 1288494.EBAPG3_18270 3.809e-204 645.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,371NE@32003|Nitrosomonadales 28216|Betaproteobacteria G Belongs to the pyruvate kinase family pykA - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C DYD2_k127_940980_33 713586.KB900536_gene1317 1.024e-131 430.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,1WZYG@135613|Chromatiales 135613|Chromatiales G Fructose-bisphosphate aldolase class-I - - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic DYD2_k127_940980_40 1121033.AUCF01000001_gene1925 3.886e-99 337.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,2JQ6A@204441|Rhodospirillales 204441|Rhodospirillales S cobalamin synthesis protein - - - - - - - - - - - - CobW_C,cobW DYD2_k127_940980_25 1120956.JHZK01000002_gene994 2.818e-166 534.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,1JP94@119043|Rhodobiaceae 28211|Alphaproteobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD2_k127_940980_58 1120956.JHZK01000002_gene1019 2.5e-46 171.0 COG1917@1|root,COG1917@2|Bacteria,1MYMN@1224|Proteobacteria,2UR93@28211|Alphaproteobacteria 28211|Alphaproteobacteria S AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2 DYD2_k127_940980_63 1502851.FG93_01002 2.46e-37 145.0 29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2U5KG@28211|Alphaproteobacteria,3JYK2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB DYD2_k127_940980_14 1510531.JQJJ01000015_gene3001 4.024e-217 692.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JX4Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA DYD2_k127_940980_16 257310.BB1573 3.967e-211 667.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,3T1XI@506|Alcaligenaceae 28216|Betaproteobacteria I Carboxyl transferase domain pccB - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD2_k127_940980_38 296591.Bpro_1464 1.938e-112 378.0 COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2VJKU@28216|Betaproteobacteria,4AB6Q@80864|Comamonadaceae 28216|Betaproteobacteria C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD DYD2_k127_940980_65 118173.KB235914_gene3750 6.029e-29 132.0 2DQHJ@1|root,336X1@2|Bacteria,1GQW2@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - DYD2_k127_940980_41 316067.Geob_0242 8.293e-96 321.0 COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,42QZY@68525|delta/epsilon subdivisions,2WMN5@28221|Deltaproteobacteria,43SVZ@69541|Desulfuromonadales 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD2_k127_940980_66 1282876.BAOK01000001_gene1988 1.564e-17 85.0 COG4770@1|root,COG4770@2|Bacteria,1NJ80@1224|Proteobacteria 1224|Proteobacteria I Acetyl propionyl-CoA carboxylase alpha subunit - - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl DYD2_k127_940980_53 1366050.N234_03190 4.65e-53 196.0 COG1802@1|root,COG1802@2|Bacteria,1RBC0@1224|Proteobacteria,2VV2K@28216|Betaproteobacteria,1K1NG@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - FCD,GntR DYD2_k127_940980_54 491916.RHECIAT_CH0003125 1.096e-52 207.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,4B8Y5@82115|Rhizobiaceae 28211|Alphaproteobacteria S sulfite oxidase - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb DYD2_k127_940980_49 552811.Dehly_0968 4.452e-61 220.0 COG2086@1|root,COG2086@2|Bacteria,2G72U@200795|Chloroflexi 200795|Chloroflexi C electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF DYD2_k127_940980_50 1132442.KB889752_gene2419 1.406e-59 224.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBCR@1386|Bacillus 91061|Bacilli C Electron transfer flavoprotein etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha DYD2_k127_940980_18 639283.Snov_0369 1.433e-199 632.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,3EYS0@335928|Xanthobacteraceae 28211|Alphaproteobacteria I Carboxyl transferase domain - - - - - - - - - - - - Carboxyl_trans DYD2_k127_94823_2 261292.Nit79A3_0883 2.473e-168 539.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,371YV@32003|Nitrosomonadales 28216|Betaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey DYD2_k127_94823_8 1132855.KB913035_gene319 6.405e-06 56.0 2EQAV@1|root,33HX0@2|Bacteria,1NPHM@1224|Proteobacteria,2WHZ1@28216|Betaproteobacteria,2KNVV@206350|Nitrosomonadales 206350|Nitrosomonadales S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 DYD2_k127_94823_5 1485544.JQKP01000002_gene1506 1.856e-89 301.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,44VM2@713636|Nitrosomonadales 28216|Betaproteobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran DYD2_k127_94823_3 1163617.SCD_n00091 2.213e-129 417.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria 28216|Betaproteobacteria L exodeoxyribonuclease iii exoA - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos DYD2_k127_94823_1 358220.C380_01555 6.818e-172 556.0 COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2WGIZ@28216|Betaproteobacteria,4A9M2@80864|Comamonadaceae 28216|Betaproteobacteria G Major facilitator superfamily ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 DYD2_k127_94823_6 1123060.JONP01000009_gene2082 2.113e-85 292.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2U6K8@28211|Alphaproteobacteria 28211|Alphaproteobacteria G xylanase chitin deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_94823_4 485913.Krac_12171 6.842e-93 314.0 COG0179@1|root,COG0179@2|Bacteria,2G6HH@200795|Chloroflexi 200795|Chloroflexi Q PFAM fumarylacetoacetate (FAA) hydrolase - - - - - - - - - - - - FAA_hydrolase DYD2_k127_94823_7 1288494.EBAPG3_5620 3.194e-85 293.0 COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2VMPA@28216|Betaproteobacteria,37223@32003|Nitrosomonadales 28216|Betaproteobacteria Q PFAM Methionine biosynthesis MetW metW - - - - - - - - - - - MetW DYD2_k127_94823_0 748247.AZKH_4541 9.7e-188 594.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,2KVER@206389|Rhodocyclales 206389|Rhodocyclales E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD2_k127_980522_3 1254432.SCE1572_35185 2.839e-65 234.0 COG1721@1|root,COG1721@2|Bacteria,1NEAC@1224|Proteobacteria,43B78@68525|delta/epsilon subdivisions,2X6KP@28221|Deltaproteobacteria,2YWA8@29|Myxococcales 28221|Deltaproteobacteria S Von Willebrand factor type A - - - - - - - - - - - - DUF58 DYD2_k127_980522_0 1499967.BAYZ01000095_gene4253 9.165e-111 372.0 COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria 2|Bacteria O ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD2_k127_980522_8 867845.KI911784_gene2141 2.022e-17 97.0 COG0318@1|root,COG0318@2|Bacteria,2G9UI@200795|Chloroflexi,3774Z@32061|Chloroflexia 32061|Chloroflexia IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - - DYD2_k127_980522_1 279714.FuraDRAFT_2138 6.452e-73 261.0 COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,2VKTY@28216|Betaproteobacteria 28216|Betaproteobacteria M Protein of unknown function (DUF3300) - - - - - - - - - - - - DUF3300 DYD2_k127_980522_9 580332.Slit_0072 2.079e-06 55.0 2A8Y5@1|root,30Y1T@2|Bacteria,1PJX0@1224|Proteobacteria,2W3X5@28216|Betaproteobacteria,44WJX@713636|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_980522_4 1121106.JQKB01000006_gene1309 1.362e-52 196.0 COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria,2JWRR@204441|Rhodospirillales 204441|Rhodospirillales S decarboxylase - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD DYD2_k127_980522_7 1232410.KI421428_gene1039 1.721e-19 102.0 COG1030@1|root,COG1030@2|Bacteria,1NKSJ@1224|Proteobacteria,432IQ@68525|delta/epsilon subdivisions,2WXUT@28221|Deltaproteobacteria 28221|Deltaproteobacteria O NfeD-like C-terminal, partner-binding - - - - - - - - - - - - NfeD DYD2_k127_980522_6 237368.SCABRO_02185 2.009e-25 118.0 COG4642@1|root,COG4642@2|Bacteria 2|Bacteria S regulation of ryanodine-sensitive calcium-release channel activity - - - - - - - - - - - - MORN DYD2_k127_980522_2 1380394.JADL01000012_gene933 7.098e-72 257.0 COG0673@1|root,COG0673@2|Bacteria,1QIQ6@1224|Proteobacteria,2U879@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA DYD2_k127_980522_5 926560.KE387023_gene1893 7.661e-28 115.0 COG2199@1|root,COG3706@2|Bacteria,1WI95@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T TIGRFAM diguanylate cyclase (GGDEF) domain - - - - - - - - - - - - GGDEF,HisKA_7TM,PAS_4 ## 3597 queries scanned ## Total time (seconds): 11.055534362792969 ## Rate: 325.36 q/s