## Sun Mar 16 11:58:31 2025 ## emapper-2.1.9 ## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD2_bin.32.fa -m mmseqs --itype genome -o DYD2_bin.32 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD2_bin.32 --cpu 8 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs DYD2_k127_107744_8 866536.Belba_1521 5.264e-138 445.0 COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,47KYQ@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh DYD2_k127_107744_6 1237149.C900_03773 7.579e-154 489.0 COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,47JU5@768503|Cytophagia 976|Bacteroidetes D Tyrosine recombinase XerC xerC - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD2_k127_107744_20 1121098.HMPREF1534_03302 4.302e-60 210.0 COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,2FR57@200643|Bacteroidia,4AQMI@815|Bacteroidaceae 976|Bacteroidetes E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II DYD2_k127_107744_21 1107311.Q767_08870 1.046e-57 209.0 COG2067@1|root,COG2067@2|Bacteria,4NGWZ@976|Bacteroidetes,1IJ7F@117743|Flavobacteriia,2NUCT@237|Flavobacterium 976|Bacteroidetes I Protein of unknown function (DUF2490) - - - - - - - - - - - - DUF2490 DYD2_k127_107744_16 1124780.ANNU01000049_gene2195 7.333e-67 232.0 COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,47PA2@768503|Cytophagia 976|Bacteroidetes U PFAM MarC family integral membrane protein marC - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD2_k127_107744_1 761193.Runsl_0785 0.0 1176.0 COG3002@1|root,COG3002@2|Bacteria,4NECE@976|Bacteroidetes,47MDY@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0753 family - - - ko:K09822 - - - - ko00000 - - - DUF2309 DYD2_k127_107744_2 761193.Runsl_0786 1.993e-290 902.0 COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47NRZ@768503|Cytophagia 976|Bacteroidetes CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N DYD2_k127_107744_15 1120965.AUBV01000003_gene390 1.265e-70 241.0 COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,47PXE@768503|Cytophagia 976|Bacteroidetes L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H DYD2_k127_107744_4 1237149.C900_03765 1.161e-169 544.0 COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47MT4@768503|Cytophagia 976|Bacteroidetes E Saccharopine dehydrogenase - - 1.5.1.10,1.5.1.7 ko:K00290,ko:K00293 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R02315 RC00215,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP DYD2_k127_107744_25 1124780.ANNU01000049_gene2200 1.673e-34 138.0 COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,47QAQ@768503|Cytophagia 976|Bacteroidetes F cytidine and deoxycytidylate deaminase cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 DYD2_k127_107744_24 1237149.C900_03757 1.314e-36 141.0 2CEYK@1|root,31W5M@2|Bacteria,4NQEQ@976|Bacteroidetes,47R7M@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF1987) - - - - - - - - - - - - DUF1987 DYD2_k127_107744_0 1237149.C900_03756 0.0 1327.0 COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia 976|Bacteroidetes V ABC-2 type transporter - - - ko:K21397 - - - - ko00000,ko02000 3.A.1 - - ABC2_membrane,ABC_tran,TerB DYD2_k127_107744_10 1237149.C900_03755 1.702e-120 393.0 29N3N@1|root,3091D@2|Bacteria,4NNZB@976|Bacteroidetes,47PVZ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_107744_19 1237149.C900_03754 8.086e-62 215.0 2EFJ6@1|root,339BJ@2|Bacteria,4NUYU@976|Bacteroidetes,47VMH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_107744_18 1237149.C900_03753 8.26e-63 223.0 COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,47QUH@768503|Cytophagia 976|Bacteroidetes S PFAM phospholipase Carboxylesterase - - - - - - - - - - - - Abhydrolase_2,FSH1 DYD2_k127_107744_12 1237149.C900_03752 4.493e-110 361.0 COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,47MMM@768503|Cytophagia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family ydfG - - - - - - - - - - - adh_short DYD2_k127_107744_14 1237149.C900_03751 6.276e-71 247.0 2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,47PC8@768503|Cytophagia 976|Bacteroidetes S Outer membrane protein beta-barrel domain porT - - - - - - - - - - - OMP_b-brl_2 DYD2_k127_107744_11 643867.Ftrac_2976 2.622e-116 378.0 COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia 976|Bacteroidetes H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran DYD2_k127_107744_3 1237149.C900_03749 2.748e-213 681.0 COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia 976|Bacteroidetes MU OmpA family - - - - - - - - - - - - OmpA,PD40 DYD2_k127_107744_13 926549.KI421517_gene2900 5.936e-77 262.0 COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,47P6H@768503|Cytophagia 976|Bacteroidetes D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 DYD2_k127_107744_23 1237149.C900_03747 2.032e-50 182.0 2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,47PWR@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_107744_5 1237149.C900_03745 4.236e-164 521.0 COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,47KNQ@768503|Cytophagia 976|Bacteroidetes G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp - 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase DYD2_k127_107744_7 1237149.C900_03744 1.234e-140 458.0 COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,47JAD@768503|Cytophagia 976|Bacteroidetes E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD2_k127_107744_22 1237149.C900_03743 1.226e-50 184.0 COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,47R52@768503|Cytophagia 976|Bacteroidetes T Low molecular weight phosphotyrosine protein phosphatase ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc DYD2_k127_107744_9 1237149.C900_03741 5.907e-128 413.0 COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692,ko:K01715 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD2_k127_107744_17 1237149.C900_03740 3.545e-65 230.0 28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,47RCK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_111001_4 1288963.ADIS_0689 2.726e-19 87.0 COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes,47MZ9@768503|Cytophagia 976|Bacteroidetes E Oxidoreductase - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N DYD2_k127_111001_2 700598.Niako_2625 1.198e-82 280.0 2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1ISGE@117747|Sphingobacteriia 976|Bacteroidetes S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 DYD2_k127_111001_3 1454007.JAUG01000007_gene2173 1.065e-57 206.0 COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,1ITI5@117747|Sphingobacteriia 976|Bacteroidetes L PFAM Transposase IS200 like - - - - - - - - - - - - Y1_Tnp DYD2_k127_111001_1 761193.Runsl_5334 1.53e-122 398.0 COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,47N4F@768503|Cytophagia 976|Bacteroidetes Q PFAM fumarylacetoacetate (FAA) hydrolase - - - - - - - - - - - - FAA_hydrolase DYD2_k127_111001_0 1237149.C900_03967 4.879e-206 645.0 COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,47MUV@768503|Cytophagia 976|Bacteroidetes O magnesium chelatase comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C DYD2_k127_1110345_4 1237149.C900_02567 4.252e-74 250.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JR2@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_1110345_3 1237149.C900_02566 1.805e-249 778.0 COG1395@1|root,COG1395@2|Bacteria,4PPUG@976|Bacteroidetes 976|Bacteroidetes K SusD family - - - - - - - - - - - - SusD-like_3,SusD_RagB DYD2_k127_1110345_2 1121875.KB907547_gene3102 0.0 1210.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia 976|Bacteroidetes S PFAM ASPIC and UnbV - - - - - - - - - - - - FG-GAP,UnbV_ASPIC,VCBS DYD2_k127_1110345_0 1237149.C900_02565 0.0 1795.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47M08@768503|Cytophagia 976|Bacteroidetes S ASPIC UnbV domain protein - - - - - - - - - - - - UnbV_ASPIC,VCBS DYD2_k127_1110345_1 1237149.C900_02564 0.0 1598.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47U10@768503|Cytophagia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS DYD2_k127_1115252_13 869213.JCM21142_72922 1.515e-20 95.0 COG3292@1|root,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop DYD2_k127_1115252_6 1237149.C900_02052 7.294e-61 215.0 COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_1115252_5 616991.JPOO01000003_gene2343 1.674e-120 398.0 COG3119@1|root,COG3119@2|Bacteria,4NF21@976|Bacteroidetes,1HZ1G@117743|Flavobacteriia,23GBB@178469|Arenibacter 976|Bacteroidetes P Metalloenzyme superfamily - - - - - - - - - - - - Metalloenzyme,Sulfatase DYD2_k127_1115252_3 468059.AUHA01000002_gene384 7.985e-131 430.0 2C31A@1|root,2Z7UP@2|Bacteria,4NECU@976|Bacteroidetes,1IQU7@117747|Sphingobacteriia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - - DYD2_k127_1115252_14 1137281.D778_02430 1.737e-15 77.0 COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1I51S@117743|Flavobacteriia 976|Bacteroidetes L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD2_k127_1115252_8 1237149.C900_03994 1.148e-52 194.0 2A7CX@1|root,334RT@2|Bacteria,4NVQR@976|Bacteroidetes,47RXJ@768503|Cytophagia 976|Bacteroidetes S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 DYD2_k127_1115252_4 1237149.C900_03993 1.417e-122 400.0 COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,47JJ9@768503|Cytophagia 976|Bacteroidetes I enoyl-CoA hydratase isomerase family - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 DYD2_k127_1115252_12 1237149.C900_03992 2.657e-29 124.0 COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,47PT7@768503|Cytophagia 976|Bacteroidetes I phosphoesterase, PA-phosphatase related - - - - - - - - - - - - - DYD2_k127_1115252_1 1237149.C900_03991 1.865e-220 692.0 COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,47KC2@768503|Cytophagia 976|Bacteroidetes K RNA polymerase, sigma-54 factor rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD DYD2_k127_1115252_0 1237149.C900_03990 4.224e-238 743.0 COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,47JG8@768503|Cytophagia 976|Bacteroidetes J Asparaginyl-tRNA synthetase asnS - 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon DYD2_k127_1115252_10 616991.JPOO01000001_gene4570 6.952e-38 153.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia 976|Bacteroidetes T Universal stress protein uspA - - - - - - - - - - - DUF2007,Usp DYD2_k127_1115252_2 926549.KI421517_gene2261 3.833e-151 493.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,47JYX@768503|Cytophagia 976|Bacteroidetes G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD2_k127_1115252_7 471854.Dfer_0195 1.969e-56 209.0 28N37@1|root,2ZB8Y@2|Bacteria,4NK7W@976|Bacteroidetes,47KK0@768503|Cytophagia 976|Bacteroidetes S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 DYD2_k127_1115252_9 153721.MYP_2551 1.177e-52 200.0 28VJR@1|root,2ZHN5@2|Bacteria,4NMGW@976|Bacteroidetes,47M7I@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1115252_11 391587.KAOT1_13127 6.291e-34 132.0 COG3813@1|root,COG3813@2|Bacteria,4NTD7@976|Bacteroidetes,1I4CJ@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1272) - - - ko:K09984 - - - - ko00000 - - - DUF1272 DYD2_k127_111717_19 925409.KI911562_gene2324 1.801e-42 183.0 COG3291@1|root,COG3291@2|Bacteria,4NN8J@976|Bacteroidetes,1IUSR@117747|Sphingobacteriia 976|Bacteroidetes U 6-phosphogluconolactonase activity - - - - - - - - - - - - CHU_C DYD2_k127_111717_8 1237149.C900_03432 4.729e-185 651.0 COG3291@1|root,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes,47NEJ@768503|Cytophagia 976|Bacteroidetes Q cell adhesion involved in biofilm formation - - - - - - - - - - - - Big_5,PKD DYD2_k127_111717_4 1237149.C900_03429 5.199e-217 690.0 COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,47Y2W@768503|Cytophagia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,Reg_prop,Response_reg DYD2_k127_111717_6 1237149.C900_03428 8.323e-206 648.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47NKU@768503|Cytophagia 976|Bacteroidetes T Sigma-54 interaction domain - - - - - - - - - - - - Response_reg,Sigma54_activat DYD2_k127_111717_16 1237149.C900_03426 1.511e-59 211.0 COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,47R0S@768503|Cytophagia 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid DYD2_k127_111717_11 1237149.C900_03424 6.584e-116 382.0 COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,47M1Q@768503|Cytophagia 976|Bacteroidetes L TIGRFAM DNA polymerase III, delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta DYD2_k127_111717_1 1237149.C900_03423 5e-324 1021.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_21,TPR_6,TPR_8 DYD2_k127_111717_9 1237149.C900_03422 8.341e-140 462.0 COG4206@1|root,COG4206@2|Bacteria,4NGYD@976|Bacteroidetes,47JSU@768503|Cytophagia 976|Bacteroidetes H Psort location OuterMembrane, score - - - - - - - - - - - - TonB_dep_Rec DYD2_k127_111717_21 1237149.C900_03421 4.054e-36 145.0 COG3087@1|root,COG3087@2|Bacteria,4NVU5@976|Bacteroidetes,47S99@768503|Cytophagia 976|Bacteroidetes D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - SPOR DYD2_k127_111717_13 1237149.C900_03420 3.63e-99 327.0 COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,47N0M@768503|Cytophagia 976|Bacteroidetes U PFAM MotA TolQ ExbB proton channel exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB DYD2_k127_111717_18 1237149.C900_03419 2.515e-46 170.0 COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,47R2X@768503|Cytophagia 976|Bacteroidetes U Biopolymer transport protein ExbD TolR exbD - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD DYD2_k127_111717_17 1237149.C900_03418 1.242e-58 213.0 COG3170@1|root,COG3170@2|Bacteria,4PKQP@976|Bacteroidetes,47JDN@768503|Cytophagia 976|Bacteroidetes NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - DYD2_k127_111717_7 153721.MYP_765 1.271e-193 612.0 COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b DYD2_k127_111717_15 1121481.AUAS01000007_gene1071 3.734e-66 229.0 COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,47PPX@768503|Cytophagia 976|Bacteroidetes S PFAM Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH DYD2_k127_111717_24 643867.Ftrac_1599 6.61e-10 61.0 2BV0E@1|root,32QD0@2|Bacteria,4PBZ5@976|Bacteroidetes,47WJJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_111717_12 1237149.C900_00026 1.516e-100 335.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - DYD2_k127_111717_2 1237149.C900_00028 1.667e-260 819.0 COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 DYD2_k127_111717_14 1237149.C900_00057 2.096e-66 236.0 COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,47PD6@768503|Cytophagia 976|Bacteroidetes S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB DYD2_k127_111717_0 1237149.C900_00062 0.0 1320.0 COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia 976|Bacteroidetes V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane,ABC_tran,TerB DYD2_k127_111717_23 1519464.HY22_12800 1.334e-12 73.0 COG3667@1|root,COG3667@2|Bacteria 2|Bacteria P copper resistance copB - - ko:K07233,ko:K07798,ko:K14588 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,CusF_Ec,HlyD_D23 DYD2_k127_111717_10 1237149.C900_00065 7.592e-137 441.0 COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,47KIZ@768503|Cytophagia 976|Bacteroidetes BQ PFAM Histone deacetylase domain - - - - - - - - - - - - Hist_deacetyl DYD2_k127_111717_5 1150600.ADIARSV_2581 1.263e-207 656.0 COG0477@1|root,COG0477@2|Bacteria,4NFY1@976|Bacteroidetes,1IP90@117747|Sphingobacteriia 976|Bacteroidetes EGP transporter - - - - - - - - - - - - Sugar_tr DYD2_k127_111717_3 1237149.C900_00071 1.345e-225 708.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia 976|Bacteroidetes L DNA polymerase Ligase (LigD) - - - - - - - - - - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N DYD2_k127_1142859_27 1239962.C943_01476 7.157e-50 184.0 COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,47KMB@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C DYD2_k127_1142859_32 926549.KI421517_gene214 1.354e-16 83.0 2E35A@1|root,32Y59@2|Bacteria,4NVFH@976|Bacteroidetes,47S3U@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1142859_2 1237149.C900_00644 2.964e-232 732.0 COG2937@1|root,COG2937@2|Bacteria,4NK5H@976|Bacteroidetes,47M20@768503|Cytophagia 976|Bacteroidetes I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD2_k127_1142859_16 1313421.JHBV01000042_gene3388 1.096e-105 353.0 COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1IQF4@117747|Sphingobacteriia 976|Bacteroidetes I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N DYD2_k127_1142859_14 880073.Calab_2890 4.989e-116 384.0 COG3616@1|root,COG3616@2|Bacteria,2NPWK@2323|unclassified Bacteria 2|Bacteria E Putative serine dehydratase domain - - 4.3.1.27 ko:K20757 - - - - ko00000,ko01000 - - - Ala_racemase_N,D-ser_dehydrat DYD2_k127_1142859_22 1237149.C900_00642 5.787e-59 206.0 COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,47Q95@768503|Cytophagia 976|Bacteroidetes FG HIT family hydrolase hinT - - ko:K02503 - - - - ko00000,ko04147 - - - HIT DYD2_k127_1142859_21 1237149.C900_00641 6.564e-71 243.0 COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,47P7N@768503|Cytophagia 976|Bacteroidetes K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N DYD2_k127_1142859_12 1237149.C900_00640 1.36e-130 422.0 COG1357@1|root,COG1357@2|Bacteria,4NY1Q@976|Bacteroidetes,47WKP@768503|Cytophagia 976|Bacteroidetes S Pentapeptide repeats (9 copies) - - - - - - - - - - - - Pentapeptide DYD2_k127_1142859_8 643867.Ftrac_3194 6.932e-166 533.0 COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,47JTX@768503|Cytophagia 976|Bacteroidetes P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD2_k127_1142859_18 1237149.C900_00637 8.891e-92 308.0 COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,47KWT@768503|Cytophagia 976|Bacteroidetes J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD DYD2_k127_1142859_11 1237149.C900_00636 4.999e-140 452.0 COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,47MC9@768503|Cytophagia 976|Bacteroidetes H Belongs to the PdxA family pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA DYD2_k127_1142859_28 1237149.C900_00635 1.241e-40 154.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - DYD2_k127_1142859_29 153721.MYP_2198 2.121e-40 155.0 COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,47QNM@768503|Cytophagia 976|Bacteroidetes S Uncharacterized ACR, COG1399 - - - - - - - - - - - - DUF177 DYD2_k127_1142859_31 1237149.C900_00633 1.6e-31 123.0 COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,47S89@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p DYD2_k127_1142859_9 1305737.JAFX01000001_gene686 1.694e-162 516.0 COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD2_k127_1142859_20 153721.MYP_3528 2.047e-72 248.0 COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,47MZS@768503|Cytophagia 976|Bacteroidetes J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD2_k127_1142859_25 1237149.C900_00629 1.965e-52 190.0 COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,47PSK@768503|Cytophagia 976|Bacteroidetes I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl DYD2_k127_1142859_1 1237149.C900_00628 7.105e-257 795.0 COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia 976|Bacteroidetes I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD2_k127_1142859_5 1237149.C900_04873 6.542e-193 608.0 COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,47M1J@768503|Cytophagia 976|Bacteroidetes L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 DYD2_k127_1142859_26 1237149.C900_04874 9.1e-51 193.0 2E7J5@1|root,3321E@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4340 DYD2_k127_1142859_4 1237149.C900_04875 3.217e-200 638.0 COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47JZF@768503|Cytophagia 976|Bacteroidetes N ABC transporter substrate-binding component GldG gldG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux DYD2_k127_1142859_19 929703.KE386491_gene670 5.302e-77 265.0 COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,47KPQ@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated ABC transporter permease protein GldF gldF - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 DYD2_k127_1142859_15 153721.MYP_2216 7.404e-113 372.0 COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47KF6@768503|Cytophagia 976|Bacteroidetes V TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA gldA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_1142859_7 1237149.C900_04882 1.814e-178 571.0 COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia 976|Bacteroidetes CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8 DYD2_k127_1142859_10 1121481.AUAS01000007_gene1034 4.74e-151 483.0 COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,47KFN@768503|Cytophagia 976|Bacteroidetes H Belongs to the FPP GGPP synthase family ispB - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt DYD2_k127_1142859_17 865937.Gilli_0923 4.476e-94 319.0 COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,1HZJW@117743|Flavobacteriia,2P7D8@244698|Gillisia 976|Bacteroidetes P Sodium/calcium exchanger protein yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD2_k127_1142859_6 313606.M23134_05264 8.078e-185 586.0 COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia 976|Bacteroidetes C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD2_k127_1142859_3 1356852.N008_18780 7.19e-221 703.0 COG3158@1|root,COG3158@2|Bacteria,4NET9@976|Bacteroidetes,47K58@768503|Cytophagia 976|Bacteroidetes P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans DYD2_k127_1142859_0 1237149.C900_03907 7.522e-319 993.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_1142859_24 1121904.ARBP01000001_gene5347 1.262e-54 200.0 2DBZX@1|root,2ZC4A@2|Bacteria,4NMEW@976|Bacteroidetes,47UX0@768503|Cytophagia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 DYD2_k127_1142859_13 450851.PHZ_c2114 3.276e-119 394.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2KIYV@204458|Caulobacterales 204458|Caulobacterales E Membrane dipeptidase (Peptidase family M19) - - - - - - - - - - - - Peptidase_M19 DYD2_k127_1146680_5 1237149.C900_04866 1.377e-32 127.0 COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,47JQ7@768503|Cytophagia 976|Bacteroidetes M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase DYD2_k127_1146680_2 153721.MYP_898 5.549e-108 355.0 COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,47THR@768503|Cytophagia 976|Bacteroidetes L Endonuclease/Exonuclease/phosphatase family xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos DYD2_k127_1146680_0 1237149.C900_00549 2.916e-308 954.0 COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,47KPX@768503|Cytophagia 976|Bacteroidetes G Glucosamine-6-phosphate isomerase nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso,PIG-L DYD2_k127_1146680_3 1237149.C900_05209 5.121e-101 338.0 COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,47JI4@768503|Cytophagia 976|Bacteroidetes E PFAM GSCFA family - - - - - - - - - - - - GSCFA DYD2_k127_1146680_1 1237149.C900_05208 1.886e-253 799.0 COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,47M2A@768503|Cytophagia 976|Bacteroidetes O COGs COG1331 Highly conserved protein containing a thioredoxin domain - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH DYD2_k127_1146680_4 1237149.C900_04045 1.628e-99 333.0 COG3595@1|root,COG3595@2|Bacteria,4NMHT@976|Bacteroidetes,47PEC@768503|Cytophagia 976|Bacteroidetes S Putative adhesin - - - - - - - - - - - - DUF4097 DYD2_k127_1146680_6 1124780.ANNU01000010_gene3645 5.553e-13 73.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - DYD2_k127_1159906_16 1237149.C900_05890 2.902e-92 315.0 COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes,47MS8@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD DYD2_k127_1159906_8 1237149.C900_05889 4.562e-182 582.0 COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,47KB6@768503|Cytophagia 976|Bacteroidetes J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr DYD2_k127_1159906_20 1237149.C900_03262 4.49e-52 200.0 COG3468@1|root,COG3468@2|Bacteria,4NEVR@976|Bacteroidetes 976|Bacteroidetes MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - OMP_b-brl_2 DYD2_k127_1159906_6 153721.MYP_2264 2.098e-216 677.0 COG0436@1|root,COG0436@2|Bacteria,4NFUY@976|Bacteroidetes,47MC8@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 DYD2_k127_1159906_0 1120968.AUBX01000018_gene2160 4.74e-322 1015.0 COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP DYD2_k127_1159906_12 926556.Echvi_2408 4.163e-153 492.0 COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,47JI6@768503|Cytophagia 976|Bacteroidetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH DYD2_k127_1159906_13 1121896.JMLU01000018_gene2868 1.269e-122 399.0 COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,1HZ20@117743|Flavobacteriia,2NUWC@237|Flavobacterium 976|Bacteroidetes E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD2_k127_1159906_2 172045.KS04_15490 1.474e-274 852.0 COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1HX1X@117743|Flavobacteriia,34PMN@308865|Elizabethkingia 976|Bacteroidetes E Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD2_k127_1159906_5 485918.Cpin_1921 3.488e-238 749.0 COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,1IPTP@117747|Sphingobacteriia 976|Bacteroidetes EH Acetolactate synthase, large subunit ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD2_k127_1159906_7 1237149.C900_01877 1.585e-186 587.0 COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,47KF1@768503|Cytophagia 976|Bacteroidetes EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN DYD2_k127_1159906_9 1267211.KI669560_gene153 6.578e-177 563.0 COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,1INNU@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C DYD2_k127_1159906_1 1189612.A33Q_4492 2.033e-310 970.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,47KEQ@768503|Cytophagia 976|Bacteroidetes E TIGRFAM Aspartate kinase thrA - 1.1.1.3,2.7.2.4 ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3 DYD2_k127_1159906_4 1185876.BN8_06126 9.605e-254 787.0 COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,47JAE@768503|Cytophagia 976|Bacteroidetes E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase DYD2_k127_1159906_18 525373.HMPREF0766_11214 1.604e-84 284.0 COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,1IQ0S@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD2_k127_1159906_11 929713.NIASO_00655 6.219e-172 545.0 COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,1INYR@117747|Sphingobacteriia 976|Bacteroidetes C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD2_k127_1159906_10 313606.M23134_05910 8.643e-175 555.0 COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,47N2Y@768503|Cytophagia 976|Bacteroidetes E Belongs to the alpha-IPM synthase homocitrate synthase family leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer DYD2_k127_1159906_3 760192.Halhy_5529 1.264e-258 805.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IPEX@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 DYD2_k127_1159906_21 1237149.C900_05879 4.804e-51 184.0 COG0824@1|root,COG0824@2|Bacteria,4NT54@976|Bacteroidetes,47RRM@768503|Cytophagia 976|Bacteroidetes S Thioesterase-like superfamily - - - - - - - - - - - - 4HBT_2 DYD2_k127_1159906_15 504472.Slin_5717 1.078e-105 351.0 COG0451@1|root,COG0451@2|Bacteria,4NG8Y@976|Bacteroidetes,47N8X@768503|Cytophagia 976|Bacteroidetes GM NAD dependent epimerase/dehydratase family - - - - - - - - - - - - Epimerase DYD2_k127_1159906_14 485918.Cpin_1595 2.052e-115 384.0 COG2067@1|root,COG2067@2|Bacteria,4NG1B@976|Bacteroidetes,1IWK5@117747|Sphingobacteriia 976|Bacteroidetes I Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 DYD2_k127_1159906_24 1313421.JHBV01000014_gene3941 2.352e-11 66.0 2E4IE@1|root,32ZDH@2|Bacteria,4NUR6@976|Bacteroidetes,1IZT1@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4266) - - - - - - - - - - - - DUF4266 DYD2_k127_1159906_17 485918.Cpin_1597 2.707e-91 310.0 COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1IQG3@117747|Sphingobacteriia 976|Bacteroidetes H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE DYD2_k127_1159906_22 485918.Cpin_1598 1.784e-28 119.0 COG0526@1|root,COG0526@2|Bacteria,4NQ50@976|Bacteroidetes 976|Bacteroidetes CO Thiol-disulfide isomerase - - - - - - - - - - - - Thioredoxin_7 DYD2_k127_1159906_19 1285586.H131_09598 3.917e-74 256.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,3IX9P@400634|Lysinibacillus 91061|Bacilli L DNA-3-methyladenine alkA - 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - AlkA_N,HhH-GPD,OGG_N DYD2_k127_1171650_2 485918.Cpin_1254 2.264e-304 945.0 COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2 DYD2_k127_1171650_9 1237149.C900_05642 8.382e-176 555.0 COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,47JAR@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD2_k127_1171650_18 1120965.AUBV01000003_gene278 1.973e-67 232.0 COG0251@1|root,COG0251@2|Bacteria,4NMAM@976|Bacteroidetes,47P6V@768503|Cytophagia 976|Bacteroidetes J PFAM Endoribonuclease L-PSP - - - - - - - - - - - - YjgF_endoribonc DYD2_k127_1171650_5 1237149.C900_02674 3.773e-213 675.0 COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 DYD2_k127_1171650_14 929703.KE386491_gene3606 1.023e-79 275.0 COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia 976|Bacteroidetes S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_1171650_1 1237149.C900_02668 0.0 1094.0 COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,47KK6@768503|Cytophagia 976|Bacteroidetes S glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C DYD2_k127_1171650_20 1237149.C900_02658 1.124e-65 231.0 COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RJQ@768503|Cytophagia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 DYD2_k127_1171650_22 1237149.C900_02657 1.354e-53 191.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - DYD2_k127_1171650_3 1237149.C900_02654 7.592e-237 744.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47TV8@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD2_k127_1171650_11 997884.HMPREF1068_03249 1.392e-99 341.0 COG2843@1|root,COG2843@2|Bacteria,4NGD2@976|Bacteroidetes,2FQ0M@200643|Bacteroidia,4AMPS@815|Bacteroidaceae 976|Bacteroidetes M Bacterial capsule synthesis protein - - - ko:K07282 - - - - ko00000 - - - PGA_cap DYD2_k127_1171650_15 1237149.C900_05677 1.319e-77 265.0 COG1407@1|root,COG1407@2|Bacteria,4NMCE@976|Bacteroidetes,47QVG@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos DYD2_k127_1171650_7 883096.HMPREF9699_00516 5.439e-189 616.0 COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia 976|Bacteroidetes U phosphate transporter - - - - - - - - - - - - PHO4 DYD2_k127_1171650_0 1237149.C900_05690 0.0 1160.0 COG1201@1|root,COG1201@2|Bacteria,4NGQ0@976|Bacteroidetes,47NAU@768503|Cytophagia 976|Bacteroidetes L DEAD DEAH box helicase lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C DYD2_k127_1171650_6 1048983.EL17_11630 1.327e-206 652.0 COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,47MFP@768503|Cytophagia 976|Bacteroidetes GM epimerase - - - - - - - - - - - - DUF2867,Epimerase,NAD_binding_10 DYD2_k127_1171650_13 1121904.ARBP01000004_gene1098 1.356e-87 294.0 COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,47K99@768503|Cytophagia 976|Bacteroidetes IQ COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - - - - - - - - - - adh_short_C2 DYD2_k127_1171650_27 388413.ALPR1_16768 4.048e-12 67.0 2CHG5@1|root,33BNC@2|Bacteria,4NXH2@976|Bacteroidetes,47T21@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1171650_25 1313301.AUGC01000003_gene2034 2.129e-21 98.0 COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes 976|Bacteroidetes S protein conserved in bacteria - - - - - - - - - - - - DUF2141 DYD2_k127_1171650_12 1237149.C900_03623 3.805e-93 314.0 COG0789@1|root,COG0789@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia 976|Bacteroidetes K PFAM MerR family regulatory protein - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 DYD2_k127_1171650_24 742726.HMPREF9448_00671 3.628e-44 166.0 COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,2FNH5@200643|Bacteroidia,22XTV@171551|Porphyromonadaceae 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_1171650_4 1237149.C900_03621 8.991e-220 690.0 COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia 976|Bacteroidetes Q TIGRFAM phytoene desaturase crtI - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase DYD2_k127_1171650_10 1237149.C900_03620 1.172e-113 373.0 COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia 976|Bacteroidetes I PFAM Squalene phytoene synthase crtB - - - - - - - - - - - SQS_PSY DYD2_k127_1171650_21 1237149.C900_03619 1.711e-63 221.0 COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,47Q5E@768503|Cytophagia 976|Bacteroidetes I NUDIX domain idi - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - NUDIX DYD2_k127_1171650_8 700598.Niako_5074 2.495e-178 568.0 COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia 976|Bacteroidetes L DNA photolyase phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 DYD2_k127_1171650_17 1237149.C900_03617 1.225e-69 239.0 COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,47QN0@768503|Cytophagia 976|Bacteroidetes S SRPBCC domain-containing protein - - - - - - - - - - - - Polyketide_cyc DYD2_k127_1171650_19 1237149.C900_03616 2.177e-67 232.0 COG3000@1|root,COG3000@2|Bacteria,4NMA9@976|Bacteroidetes,47PV8@768503|Cytophagia 976|Bacteroidetes I PFAM Fatty acid hydroxylase crtZ - 1.14.15.24 ko:K15746 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00372 R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747 RC00478,RC00704,RC02629 ko00000,ko00001,ko00002,ko01000 - - - FA_hydroxylase DYD2_k127_1171650_16 1237149.C900_03615 2.145e-75 258.0 arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia 976|Bacteroidetes S lycopene cyclase - - - - - - - - - - - - - DYD2_k127_1184504_6 1237149.C900_02589 2.924e-49 184.0 arCOG07533@1|root,2ZF5I@2|Bacteria,4NMWZ@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4386) - - - - - - - - - - - - DUF4386 DYD2_k127_1184504_0 1189612.A33Q_0629 0.0 1562.0 COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia 976|Bacteroidetes KLT AAA ATPase domain - - - - - - - - - - - - AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase DYD2_k127_1184504_1 1189612.A33Q_0628 2.883e-218 699.0 COG0753@1|root,COG0753@2|Bacteria 2|Bacteria C catalase activity - - - - - - - - - - - - Lipoxygenase DYD2_k127_1184504_3 1189612.A33Q_0627 1.308e-116 386.0 COG0753@1|root,COG0753@2|Bacteria 2|Bacteria C catalase activity - - - - - - - - - - - - - DYD2_k127_1184504_5 761193.Runsl_2910 8.91e-60 211.0 COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,47PZU@768503|Cytophagia 976|Bacteroidetes M Fasciclin domain - - - - - - - - - - - - Fasciclin DYD2_k127_1184504_2 1123277.KB893172_gene756 7.726e-152 487.0 COG1506@1|root,COG1506@2|Bacteria,4NH1V@976|Bacteroidetes 976|Bacteroidetes E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 DYD2_k127_1184504_4 1408473.JHXO01000010_gene3552 1.374e-89 300.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FMCU@200643|Bacteroidia 976|Bacteroidetes G Glycosyl hydrolase family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C DYD2_k127_1189978_1 1237149.C900_04588 9.039e-131 421.0 COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,47JYP@768503|Cytophagia 976|Bacteroidetes H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 DYD2_k127_1189978_2 1237149.C900_04589 4.888e-126 411.0 COG0226@1|root,COG0226@2|Bacteria,4NKND@976|Bacteroidetes,47PVA@768503|Cytophagia 976|Bacteroidetes P Type IX secretion system membrane protein PorP/SprF - - - - - - - - - - - - PorP_SprF DYD2_k127_1189978_0 1237149.C900_04590 8.539e-199 623.0 COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,47KHB@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated lipoprotein GldK gldK - - - - - - - - - - - FGE-sulfatase DYD2_k127_1189978_4 1237149.C900_04591 7.847e-113 370.0 28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,47MA3@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated protein GldL gldL - - - - - - - - - - - - DYD2_k127_1189978_3 1237149.C900_04592 1.337e-125 419.0 28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,47JTS@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated protein GldM gldM - - - - - - - - - - - GldM_C,GldM_N DYD2_k127_1201116_3 1237149.C900_02381 1.626e-178 564.0 COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family pcd - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_1201116_4 1237149.C900_02380 4.295e-164 529.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia 976|Bacteroidetes O PDZ domain (Also known as DHR or GLGF) htrA - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 DYD2_k127_1201116_6 643867.Ftrac_2445 5.559e-40 152.0 COG0071@1|root,COG0071@2|Bacteria,4NSJB@976|Bacteroidetes,47R4W@768503|Cytophagia 976|Bacteroidetes O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD2_k127_1201116_0 1237149.C900_00735 0.0 1522.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12 DYD2_k127_1201116_1 1237149.C900_00734 0.0 1065.0 COG2185@1|root,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,47JW5@768503|Cytophagia 976|Bacteroidetes I Methylmalonyl-CoA mutase mutB - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase DYD2_k127_1201116_5 1237149.C900_00733 1.307e-60 223.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,47JP5@768503|Cytophagia 976|Bacteroidetes I Methylmalonyl-CoA mutase N-terminal domain subunit mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase DYD2_k127_1201116_2 153721.MYP_4201 1.493e-178 571.0 COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,47KR6@768503|Cytophagia 976|Bacteroidetes L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N DYD2_k127_1201116_7 1237149.C900_01113 1.25e-09 60.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity degQ - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD2_k127_121043_5 1124780.ANNU01000010_gene3645 2.257e-34 135.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - DYD2_k127_121043_0 471854.Dfer_3377 5.719e-287 904.0 COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,47K5C@768503|Cytophagia 976|Bacteroidetes L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII DYD2_k127_121043_3 641524.ADICYQ_1702 2.25e-139 445.0 COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,47JN8@768503|Cytophagia 976|Bacteroidetes S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD2_k127_121043_4 1237149.C900_05671 2.014e-47 177.0 2CYF8@1|root,32T43@2|Bacteria,4NUAU@976|Bacteroidetes,47RBY@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_121043_1 1237149.C900_05672 3.523e-225 701.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia 976|Bacteroidetes H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 DYD2_k127_121043_2 1237149.C900_00266 2.296e-152 492.0 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,47K9B@768503|Cytophagia 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 DYD2_k127_1220676_2 1237149.C900_05252 1.324e-82 278.0 COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family tesA - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 DYD2_k127_1220676_1 1237149.C900_05253 3.058e-100 331.0 COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia 976|Bacteroidetes Q ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_1220676_0 1237149.C900_05254 4.404e-206 655.0 COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia 976|Bacteroidetes Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_1254381_9 1237149.C900_05076 6.501e-110 357.0 COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,47KQK@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_1254381_7 1237149.C900_05077 4.337e-131 425.0 COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,47KCQ@768503|Cytophagia 976|Bacteroidetes E Tryptophan 2,3-dioxygenase kynA - 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase DYD2_k127_1254381_3 1237149.C900_05078 1.499e-225 714.0 COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47JEK@768503|Cytophagia 976|Bacteroidetes S MORN repeat variant - - - - - - - - - - - - MORN_2 DYD2_k127_1254381_4 1239962.C943_04199 1.734e-225 709.0 COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,47K0W@768503|Cytophagia 976|Bacteroidetes S FAD dependent oxidoreductase - - - ko:K07137 - - - - ko00000 - - - FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2 DYD2_k127_1254381_13 1237149.C900_05080 3.724e-51 183.0 COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,47RGM@768503|Cytophagia 976|Bacteroidetes S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 DYD2_k127_1254381_8 1121373.KB903637_gene946 1.191e-111 370.0 COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,47JG3@768503|Cytophagia 976|Bacteroidetes S TIGRFAM polyphosphate nucleotide phosphotransferase, PPK2 family - - - - - - - - - - - - PPK2 DYD2_k127_1254381_1 1237149.C900_01449 0.0 1088.0 COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,47K1X@768503|Cytophagia 976|Bacteroidetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD2_k127_1254381_2 1237149.C900_01447 4.415e-237 745.0 COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,47KMU@768503|Cytophagia 976|Bacteroidetes P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N DYD2_k127_1254381_11 1237149.C900_01447 1.465e-61 214.0 COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,47KMU@768503|Cytophagia 976|Bacteroidetes P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N DYD2_k127_1254381_10 1237149.C900_00622 4.767e-102 340.0 COG0248@1|root,COG0248@2|Bacteria,4NEI0@976|Bacteroidetes,47KHJ@768503|Cytophagia 976|Bacteroidetes FP PFAM Ppx GppA phosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA DYD2_k127_1254381_6 1237149.C900_00621 1.491e-163 520.0 COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,47KPH@768503|Cytophagia 976|Bacteroidetes E Homocysteine S-methyltransferase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans DYD2_k127_1254381_0 1237149.C900_01371 0.0 1316.0 COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,47XZT@768503|Cytophagia 976|Bacteroidetes E B12 binding domain metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind DYD2_k127_1254381_12 869213.JCM21142_93651 1.134e-53 191.0 COG0614@1|root,COG0614@2|Bacteria,4NR62@976|Bacteroidetes,47XUB@768503|Cytophagia 976|Bacteroidetes P PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_3 DYD2_k127_1254381_5 1237149.C900_01372 1.387e-165 525.0 COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,47KQ7@768503|Cytophagia 976|Bacteroidetes E Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR DYD2_k127_1254381_14 1168034.FH5T_10530 1.801e-18 98.0 COG2335@1|root,COG2335@2|Bacteria,4NGU3@976|Bacteroidetes,2FQ02@200643|Bacteroidia 976|Bacteroidetes M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - ko:K19519 - - - - ko00000,ko04516 - - - DUF5108,Fasciclin DYD2_k127_1356266_1 471854.Dfer_3802 1.698e-178 563.0 COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia 976|Bacteroidetes D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc DYD2_k127_1356266_3 929556.Solca_3844 3.132e-43 161.0 COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,1ISZQ@117747|Sphingobacteriia 976|Bacteroidetes S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - - - - - - - - - - UPF0054 DYD2_k127_1356266_2 1237149.C900_03438 1.377e-64 222.0 COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase rsbW - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 DYD2_k127_1356266_0 1237149.C900_03437 2.698e-253 809.0 COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,47NNE@768503|Cytophagia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - DUF4175 DYD2_k127_1358159_2 269798.CHU_3286 1.895e-50 181.0 COG0357@1|root,COG0357@2|Bacteria,4PM2I@976|Bacteroidetes,47Y0D@768503|Cytophagia 976|Bacteroidetes M Methyltransferase domain - - - - - - - - - - - - Methyltransf_32 DYD2_k127_1358159_0 1250232.JQNJ01000001_gene1888 2.574e-299 923.0 COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,1HYII@117743|Flavobacteriia 976|Bacteroidetes Q Imidazolonepropionase and related - - - - - - - - - - - - Amidohydro_1 DYD2_k127_1358159_5 566466.NOR53_787 9.925e-28 116.0 COG0006@1|root,COG0006@2|Bacteria,1MVHD@1224|Proteobacteria,1SKX1@1236|Gammaproteobacteria,1J932@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 DYD2_k127_1358159_1 566466.NOR53_787 1.178e-135 437.0 COG0006@1|root,COG0006@2|Bacteria,1MVHD@1224|Proteobacteria,1SKX1@1236|Gammaproteobacteria,1J932@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 DYD2_k127_1358159_3 1237149.C900_03068 1.188e-45 172.0 2CDET@1|root,2ZBN1@2|Bacteria,4NN6D@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1358159_4 1237149.C900_03067 4.182e-42 160.0 28M39@1|root,2ZAHI@2|Bacteria,4NM3I@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1372927_2 1121373.KB903625_gene3231 2.484e-57 204.0 COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47MRD@768503|Cytophagia 976|Bacteroidetes Q ABC-type transport system involved in resistance to organic solvents periplasmic component - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD2_k127_1372927_1 1131812.JQMS01000001_gene2375 6.214e-117 380.0 COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1HXP0@117743|Flavobacteriia,2NT00@237|Flavobacterium 976|Bacteroidetes Q Organic solvent ABC transporter ATP-binding protein - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD2_k127_1372927_0 1131812.JQMS01000001_gene2376 3.907e-122 395.0 COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1HX62@117743|Flavobacteriia,2NSJ5@237|Flavobacterium 976|Bacteroidetes Q Belongs to the MlaE permease family - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD2_k127_1414652_16 1124780.ANNU01000052_gene3576 1.528e-10 64.0 2EJD3@1|root,33D44@2|Bacteria,4NP3M@976|Bacteroidetes,47PW7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - SPOR DYD2_k127_1414652_3 1237149.C900_04444 1.514e-186 590.0 COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47KGA@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase family M20 M25 M40 amaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 DYD2_k127_1414652_5 1124780.ANNU01000052_gene3570 7.468e-90 303.0 COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,47MXM@768503|Cytophagia 976|Bacteroidetes I Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P) pcrB - - ko:K07094 - - - - ko00000,ko01000 - - - PcrB DYD2_k127_1414652_2 1237149.C900_04460 5.031e-204 639.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47JZA@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_1414652_6 643867.Ftrac_2046 9.096e-89 298.0 COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,47MH4@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase, membrane zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 DYD2_k127_1414652_10 153721.MYP_2028 9.308e-59 207.0 COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,47PFX@768503|Cytophagia 976|Bacteroidetes H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like DYD2_k127_1414652_7 1237149.C900_04463 3.756e-84 289.0 COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,47JZY@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised protein family (UPF0104) - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD2_k127_1414652_11 1237149.C900_04464 3.227e-55 194.0 COG0853@1|root,COG0853@2|Bacteria,4NQ42@976|Bacteroidetes,47QA8@768503|Cytophagia 976|Bacteroidetes H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox DYD2_k127_1414652_8 1237149.C900_04465 1.527e-79 274.0 COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,47MNB@768503|Cytophagia 976|Bacteroidetes H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase DYD2_k127_1414652_4 1237149.C900_04466 3.507e-144 460.0 COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,47KUD@768503|Cytophagia 976|Bacteroidetes G PFAM Starch synthase catalytic domain glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5 DYD2_k127_1414652_13 1249997.JHZW01000003_gene3515 1.981e-12 80.0 28J4T@1|root,2Z90P@2|Bacteria,4NHUC@976|Bacteroidetes,1HZE4@117743|Flavobacteriia,2PG8B@252356|Maribacter 976|Bacteroidetes S Domain of unknown function (DUF4270) - - - - - - - - - - - - DUF4270 DYD2_k127_1414652_0 1237149.C900_04468 0.0 1006.0 COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,47KVG@768503|Cytophagia 976|Bacteroidetes M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS DYD2_k127_1414652_9 1237149.C900_04480 1.104e-74 257.0 COG1250@1|root,COG1250@2|Bacteria,4NWYY@976|Bacteroidetes,47VDX@768503|Cytophagia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - 3HCDH DYD2_k127_1414652_12 1121859.KB890738_gene3624 3.762e-52 186.0 COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,47QE4@768503|Cytophagia 976|Bacteroidetes J TIGRFAM endoribonuclease L-PSP yjgF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP DYD2_k127_1414652_1 1124780.ANNU01000017_gene1877 1.083e-214 677.0 COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c DYD2_k127_1414652_17 1237149.C900_04484 3.463e-07 54.0 2E4W4@1|root,32ZQB@2|Bacteria,4NUZZ@976|Bacteroidetes,47RZI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_146307_2 929556.Solca_2236 1.879e-33 132.0 COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD2_k127_146307_1 929556.Solca_2235 3.971e-43 168.0 2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_146307_0 929556.Solca_2234 1.158e-201 635.0 COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1INKZ@117747|Sphingobacteriia 976|Bacteroidetes C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD DYD2_k127_146307_3 929556.Solca_2233 3.441e-30 119.0 COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S dicluster domain - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11 DYD2_k127_1477149_5 84588.SYNW2382 2.419e-05 46.0 COG0445@1|root,COG0445@2|Bacteria,1G0MP@1117|Cyanobacteria,1GYGZ@1129|Synechococcus 1117|Cyanobacteria D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc DYD2_k127_1477149_4 643867.Ftrac_0684 1.441e-28 117.0 COG2827@1|root,COG2827@2|Bacteria,4NV6N@976|Bacteroidetes,47X40@768503|Cytophagia 976|Bacteroidetes L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD2_k127_1477149_1 1237149.C900_04233 4.423e-175 567.0 COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,47JCU@768503|Cytophagia 976|Bacteroidetes S Permease YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ DYD2_k127_1477149_3 1237149.C900_04234 1.316e-36 139.0 COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,47R7H@768503|Cytophagia 976|Bacteroidetes J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 DYD2_k127_1477149_0 1237149.C900_04235 0.0 1048.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,47KTE@768503|Cytophagia 976|Bacteroidetes J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 DYD2_k127_1477149_2 1237149.C900_04236 1.093e-142 454.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD2_k127_1487683_0 1121889.AUDM01000049_gene1307 2.841e-133 441.0 COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,1HYXT@117743|Flavobacteriia,2NVAA@237|Flavobacterium 976|Bacteroidetes L COG3666 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 DYD2_k127_1487683_1 1358423.N180_19710 9.528e-31 124.0 COG1192@1|root,COG1192@2|Bacteria,4PM8H@976|Bacteroidetes 976|Bacteroidetes D Involved in chromosome partitioning - - - - - - - - - - - - - DYD2_k127_1501683_14 1122605.KB893637_gene3290 1.773e-14 77.0 COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes,1IQJR@117747|Sphingobacteriia 976|Bacteroidetes H Outer membrane cobalamin receptor protein btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec DYD2_k127_1501683_3 1237149.C900_03808 3.182e-127 421.0 COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,47MZX@768503|Cytophagia 976|Bacteroidetes P PFAM periplasmic binding protein btuF - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 DYD2_k127_1501683_10 1121904.ARBP01000001_gene5730 1.887e-56 197.0 COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,47Q8W@768503|Cytophagia 976|Bacteroidetes J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 DYD2_k127_1501683_2 269798.CHU_3164 0.0 1210.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,47M8E@768503|Cytophagia 976|Bacteroidetes J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 DYD2_k127_1501683_7 1120966.AUBU01000002_gene1928 2.214e-75 255.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,47P7P@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 DYD2_k127_1501683_8 643867.Ftrac_3028 2.472e-69 236.0 COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,47PCE@768503|Cytophagia 976|Bacteroidetes J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 DYD2_k127_1501683_12 1121904.ARBP01000010_gene2337 1.382e-50 181.0 COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,47R37@768503|Cytophagia 976|Bacteroidetes T Protein of unknown function (DUF3467) - - - - - - - - - - - - DUF3467 DYD2_k127_1501683_0 1237149.C900_04676 0.0 2477.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,47JP0@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 DYD2_k127_1501683_1 1237149.C900_04675 0.0 2280.0 COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,47JXH@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 DYD2_k127_1501683_11 1237149.C900_04674 1.334e-50 182.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,47PSQ@768503|Cytophagia 976|Bacteroidetes J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N DYD2_k127_1501683_9 1237149.C900_04673 7.052e-67 231.0 COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,47JGP@768503|Cytophagia 976|Bacteroidetes J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 DYD2_k127_1501683_4 1237149.C900_04672 7.534e-114 370.0 COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,47JJZ@768503|Cytophagia 976|Bacteroidetes J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 DYD2_k127_1501683_6 1237149.C900_04671 7.172e-81 270.0 COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,47PEZ@768503|Cytophagia 976|Bacteroidetes J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N DYD2_k127_1501683_5 1237149.C900_04670 1.712e-99 326.0 COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,47KBF@768503|Cytophagia 976|Bacteroidetes K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG DYD2_k127_1501683_13 1237149.C900_04669 1.12e-19 89.0 COG0690@1|root,COG0690@2|Bacteria,4NX53@976|Bacteroidetes,47RVC@768503|Cytophagia 976|Bacteroidetes U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE DYD2_k127_1531576_2 1237149.C900_04085 8.212e-150 502.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_1531576_0 1237149.C900_04087 3.109e-269 851.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_1531576_1 1121904.ARBP01000010_gene2393 2.212e-215 693.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JYF@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_1531576_3 1237149.C900_04088 1.036e-54 196.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JYF@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_1581_1 1237149.C900_05255 9.17e-59 214.0 COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia 976|Bacteroidetes N C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD,SBBP DYD2_k127_1581_0 1237149.C900_05254 3.06e-129 420.0 COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia 976|Bacteroidetes Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_1582373_3 504472.Slin_4879 2.001e-68 235.0 28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,47MBS@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2480) - - - - - - - - - - - - DUF2480 DYD2_k127_1582373_2 1237149.C900_04945 2.64e-72 250.0 COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,47NST@768503|Cytophagia 976|Bacteroidetes O TIGRFAM universal bacterial protein YeaZ yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 DYD2_k127_1582373_0 1237149.C900_04944 7.974e-193 617.0 COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 DYD2_k127_1582373_4 1237149.C900_04943 2.944e-29 120.0 COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,47S3A@768503|Cytophagia 976|Bacteroidetes J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P DYD2_k127_1582373_5 743722.Sph21_0328 3.62e-18 84.0 COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 DYD2_k127_1582373_1 1237149.C900_04938 1.986e-96 319.0 COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,47NUW@768503|Cytophagia 976|Bacteroidetes G Belongs to the carbohydrate kinase PfkB family - - - - - - - - - - - - PfkB DYD2_k127_159535_1 945713.IALB_0283 1.045e-08 59.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - BNR,Sortilin-Vps10 DYD2_k127_159535_0 1237149.C900_04041 1.906e-270 854.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47TMG@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_1631670_7 1237149.C900_00378 2.099e-26 116.0 2CB8F@1|root,34CDS@2|Bacteria,4P8GI@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1631670_3 1185876.BN8_01180 7.404e-58 205.0 COG1595@1|root,COG1595@2|Bacteria,4NRSU@976|Bacteroidetes,47UTH@768503|Cytophagia 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_1631670_1 1408813.AYMG01000006_gene4141 1.85e-124 402.0 COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1IRQX@117747|Sphingobacteriia 976|Bacteroidetes G Haloacid Dehalogenase Superfamily Class (subfamily) IIA - - - ko:K02566 - - - - ko00000 - - - Hydrolase_6,Hydrolase_like DYD2_k127_1631670_4 1123057.P872_14960 1.967e-47 175.0 COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,47KFE@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 DYD2_k127_1631670_6 388413.ALPR1_15964 3.329e-42 156.0 COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,47KFE@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 DYD2_k127_1631670_2 1250232.JQNJ01000001_gene3905 2.122e-104 355.0 COG0521@1|root,COG0521@2|Bacteria,4NHZS@976|Bacteroidetes,1I1AI@117743|Flavobacteriia 976|Bacteroidetes H Starch-binding associating with outer membrane - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like,SusD-like_2,SusD_RagB DYD2_k127_1631670_0 1123278.KB893603_gene1801 0.0 1078.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47KVA@768503|Cytophagia 976|Bacteroidetes HP TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_1631670_8 1268240.ATFI01000003_gene5083 0.000376 50.0 2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,4AND5@815|Bacteroidaceae 976|Bacteroidetes S Domain of unknown function (DUF4251) - - - - - - - - - - - - DUF4251 DYD2_k127_1631670_5 1237149.C900_00075 4.973e-46 173.0 COG4251@1|root,COG4251@2|Bacteria 2|Bacteria T photoreceptor activity - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_9,Reg_prop,Response_reg,Y_Y_Y DYD2_k127_175670_4 1237149.C900_04232 9.751e-47 171.0 COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,47R94@768503|Cytophagia 976|Bacteroidetes S Pfam Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD2_k127_175670_3 153721.MYP_1941 3.703e-86 291.0 COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47KCT@768503|Cytophagia 976|Bacteroidetes S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD2_k127_175670_0 1121904.ARBP01000006_gene3945 1.277e-224 718.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 DYD2_k127_175670_1 1237149.C900_05133 2.46e-192 608.0 COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,47KKZ@768503|Cytophagia 976|Bacteroidetes F PFAM Na dependent nucleoside transporter nupC - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N DYD2_k127_175670_2 1237149.C900_05134 1.053e-89 300.0 COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,47KJI@768503|Cytophagia 976|Bacteroidetes L PFAM Uncharacterised ACR, COG1259 - - - ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR DYD2_k127_175670_5 1237149.C900_05135 1.529e-15 76.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,47JUQ@768503|Cytophagia 976|Bacteroidetes C Electron transfer flavoprotein, alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha DYD2_k127_1760074_4 1237149.C900_01576 6.414e-182 576.0 COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,47JSE@768503|Cytophagia 976|Bacteroidetes S PFAM Nucleoside recognition spmA - - ko:K06373 - - - - ko00000 - - - Gate DYD2_k127_1760074_2 1124780.ANNU01000005_gene2467 2.955e-243 767.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 DYD2_k127_1760074_26 1237149.C900_02632 3.515e-28 115.0 COG4095@1|root,COG4095@2|Bacteria 2|Bacteria S Sugar efflux transporter for intercellular exchange - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - MtN3_slv,PQ-loop DYD2_k127_1760074_29 1250005.PHEL85_1251 5.902e-20 101.0 2F4EN@1|root,33X4W@2|Bacteria,4P3J2@976|Bacteroidetes,1I902@117743|Flavobacteriia,3VWTF@52959|Polaribacter 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1760074_31 471854.Dfer_2932 5.964e-15 82.0 2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,47R28@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1760074_33 866536.Belba_3336 2.593e-06 55.0 2DYS9@1|root,34AWN@2|Bacteria,4P6QB@976|Bacteroidetes,47VWN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1760074_18 926549.KI421517_gene1358 4.315e-77 261.0 COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,47N5B@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_1760074_16 1121904.ARBP01000006_gene3948 1.368e-108 362.0 COG1932@1|root,COG1932@2|Bacteria,4PKN4@976|Bacteroidetes,47J9A@768503|Cytophagia 976|Bacteroidetes EH Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine - - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD2_k127_1760074_17 1237149.C900_00736 1.494e-100 334.0 COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,47NAG@768503|Cytophagia 976|Bacteroidetes J PFAM Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans DYD2_k127_1760074_1 1237149.C900_01327 3.984e-300 931.0 COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,47MQ2@768503|Cytophagia 976|Bacteroidetes EH PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,HAD DYD2_k127_1760074_22 321332.CYB_2366 2.052e-56 199.0 COG0394@1|root,COG0394@2|Bacteria,1G5Z0@1117|Cyanobacteria,1H2BD@1129|Synechococcus 1117|Cyanobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc DYD2_k127_1760074_28 1237149.C900_03390 6.229e-26 113.0 COG1246@1|root,COG1246@2|Bacteria,4NVX0@976|Bacteroidetes,47SE9@768503|Cytophagia 976|Bacteroidetes E Acetyltransferase (GNAT) domain - - 2.3.1.1 ko:K00619 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,Acetyltransf_10 DYD2_k127_1760074_11 700598.Niako_4079 1.676e-117 383.0 COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,1IP66@117747|Sphingobacteriia 976|Bacteroidetes Q Methylase involved in ubiquinone menaquinone biosynthesis arsM - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 DYD2_k127_1760074_24 269798.CHU_1513 2.427e-42 157.0 COG0640@1|root,COG0640@2|Bacteria,4NQK3@976|Bacteroidetes,47R2A@768503|Cytophagia 976|Bacteroidetes K PFAM Bacterial regulatory protein, arsR family - - - - - - - - - - - - HTH_20,HTH_5 DYD2_k127_1760074_15 1121104.AQXH01000001_gene1951 1.08e-113 379.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - - - - - - - - - - Amidohydro_1 DYD2_k127_1760074_0 925409.KI911562_gene2337 1.3e-311 971.0 COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1IR7E@117747|Sphingobacteriia 976|Bacteroidetes S Transferrin receptor-like dimerisation domain - - 3.4.17.21 ko:K01301 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28,TFR_dimer DYD2_k127_1760074_7 1237149.C900_00613 1.224e-167 530.0 COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,47JQN@768503|Cytophagia 976|Bacteroidetes G PFAM Transketolase, C-terminal domain dxs - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD2_k127_1760074_27 421531.IX38_11935 1.546e-26 115.0 COG0251@1|root,COG0251@2|Bacteria,4NMXE@976|Bacteroidetes,1I1GR@117743|Flavobacteriia,3ZSJM@59732|Chryseobacterium 976|Bacteroidetes J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD2_k127_1760074_8 643867.Ftrac_0981 1.35e-146 468.0 COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,47JJD@768503|Cytophagia 976|Bacteroidetes G PFAM Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD2_k127_1760074_23 1492737.FEM08_21600 2.326e-45 172.0 COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia,2NVS1@237|Flavobacterium 976|Bacteroidetes P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA DYD2_k127_1760074_20 1189612.A33Q_1683 3.957e-70 242.0 COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,47PUA@768503|Cytophagia 976|Bacteroidetes O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD2_k127_1760074_5 1237149.C900_00938 9.595e-178 576.0 COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,47JZB@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD2_k127_1760074_21 1122179.KB890418_gene3749 9.657e-65 227.0 COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,1INU6@117747|Sphingobacteriia 976|Bacteroidetes Q PFAM fumarylacetoacetate (FAA) hydrolase fahA - - - - - - - - - - - FAA_hydrolase DYD2_k127_1760074_14 1237149.C900_00936 4.63e-114 373.0 COG4783@1|root,COG4783@2|Bacteria,4PKN7@976|Bacteroidetes,47YC0@768503|Cytophagia 976|Bacteroidetes S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD2_k127_1760074_19 1048983.EL17_13305 3.609e-73 253.0 COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,47KPR@768503|Cytophagia 976|Bacteroidetes EH Reduction of activated sulfate into sulfite cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct DYD2_k127_1760074_12 1237149.C900_05142 8.454e-116 377.0 COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,47N5P@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T DYD2_k127_1760074_6 1237149.C900_05141 1.333e-172 552.0 COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,47JEX@768503|Cytophagia 976|Bacteroidetes M Mur ligase middle domain mpl - 6.3.2.45,6.3.2.8 ko:K01924,ko:K02558 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD2_k127_1760074_3 1237149.C900_05140 1.463e-233 732.0 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C DYD2_k127_1760074_9 1237149.C900_05138 1.399e-132 430.0 COG0604@1|root,COG0604@2|Bacteria,4NGIY@976|Bacteroidetes,47KMW@768503|Cytophagia 976|Bacteroidetes C alcohol dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD2_k127_1760074_32 743722.Sph21_5178 5.87e-09 60.0 COG3237@1|root,COG3237@2|Bacteria,4NUMZ@976|Bacteroidetes,1ITX1@117747|Sphingobacteriia 976|Bacteroidetes S Belongs to the UPF0337 (CsbD) family - - - - - - - - - - - - CsbD DYD2_k127_1760074_34 251221.35214196 8.339e-06 52.0 COG4980@1|root,COG4980@2|Bacteria,1G7T1@1117|Cyanobacteria 1117|Cyanobacteria S gas vesicle protein - - - - - - - - - - - - YtxH DYD2_k127_1760074_30 945713.IALB_2251 2.06e-15 79.0 COG3118@1|root,COG3118@2|Bacteria 2|Bacteria O belongs to the thioredoxin family trxA - - ko:K03671,ko:K20543 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko02000,ko03110 1.B.55.3 - - TPR_19,Thioredoxin DYD2_k127_1760074_13 1120965.AUBV01000013_gene1286 4.081e-115 375.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,47KZ2@768503|Cytophagia 976|Bacteroidetes C Electron transfer flavoprotein etfB - - ko:K03521 - - - - ko00000 - - - ETF DYD2_k127_1760074_10 1237149.C900_05135 2.823e-120 391.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,47JUQ@768503|Cytophagia 976|Bacteroidetes C Electron transfer flavoprotein, alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha DYD2_k127_1761686_7 1237149.C900_04422 2.585e-92 309.0 28KMN@1|root,2ZA61@2|Bacteria,4NJ9P@976|Bacteroidetes,47P0N@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4062 DYD2_k127_1761686_0 1237149.C900_04421 0.0 1072.0 COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia 976|Bacteroidetes C - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - HEAT_2,cNMP_binding DYD2_k127_1761686_3 1121904.ARBP01000001_gene5843 5.042e-133 434.0 COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,47KMT@768503|Cytophagia 976|Bacteroidetes J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth DYD2_k127_1761686_4 1237149.C900_01561 1.37e-106 357.0 COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47KCD@768503|Cytophagia 976|Bacteroidetes M PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain menC - - - - - - - - - - - MR_MLE_C DYD2_k127_1761686_6 1237149.C900_04765 2.182e-104 344.0 COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,47P4U@768503|Cytophagia 976|Bacteroidetes K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,Peptidase_S24 DYD2_k127_1761686_8 1237149.C900_04757 6.054e-87 300.0 COG0318@1|root,COG0318@2|Bacteria,4NEXK@976|Bacteroidetes,47KUG@768503|Cytophagia 976|Bacteroidetes IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C DYD2_k127_1761686_2 1356852.N008_14585 2.358e-150 478.0 COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,47JYS@768503|Cytophagia 976|Bacteroidetes H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB - 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD2_k127_1761686_1 1124780.ANNU01000019_gene1770 2.676e-177 572.0 COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,47JS5@768503|Cytophagia 976|Bacteroidetes H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N DYD2_k127_1761686_5 1121904.ARBP01000003_gene6234 2.414e-106 358.0 COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,47K5Z@768503|Cytophagia 976|Bacteroidetes HQ PFAM chorismate binding enzyme entC - 5.4.4.2 ko:K02361,ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind DYD2_k127_1761686_10 1279009.ADICEAN_01908 2.064e-55 197.0 COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,47QEZ@768503|Cytophagia 976|Bacteroidetes Q PFAM thioesterase superfamily ydiI - 3.1.2.28 ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 - - - 4HBT,Hydrolase_3 DYD2_k127_1761686_9 1227739.Hsw_2924 3.177e-70 241.0 COG0406@1|root,COG0406@2|Bacteria,4NFX5@976|Bacteroidetes,47JSV@768503|Cytophagia 976|Bacteroidetes G phosphoglycerate mutase family gpm - - - - - - - - - - - His_Phos_1 DYD2_k127_1766061_1 929703.KE386491_gene3907 8.715e-154 492.0 COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia 976|Bacteroidetes F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase DYD2_k127_1766061_6 1121373.KB903664_gene2657 2.135e-08 63.0 COG3637@1|root,COG3637@2|Bacteria,4NTRC@976|Bacteroidetes,47SSV@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl DYD2_k127_1766061_4 997884.HMPREF1068_00878 2.836e-20 98.0 28N4A@1|root,2ZA01@2|Bacteria,4NK0T@976|Bacteroidetes,2G36K@200643|Bacteroidia,4AWAJ@815|Bacteroidaceae 976|Bacteroidetes S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 DYD2_k127_1766061_5 1123276.KB893284_gene5110 8.807e-10 69.0 COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia 976|Bacteroidetes S TPR repeat-containing protein - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 DYD2_k127_1766061_0 1121931.AUHG01000011_gene1907 1.822e-292 907.0 COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,1HY43@117743|Flavobacteriia 976|Bacteroidetes T gtp-binding protein typa typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 DYD2_k127_1766061_2 1279009.ADICEAN_04205 1.839e-101 339.0 COG1092@1|root,COG1092@2|Bacteria,4NGJX@976|Bacteroidetes,47MFA@768503|Cytophagia 976|Bacteroidetes J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM DYD2_k127_1766061_3 1158294.JOMI01000009_gene886 1.453e-37 146.0 COG0566@1|root,COG0566@2|Bacteria,4NEFJ@976|Bacteroidetes,2FRCP@200643|Bacteroidia 976|Bacteroidetes J SpoU rRNA Methylase family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind DYD2_k127_1796151_10 992406.RIA_0349 7.043e-08 56.0 28JH1@1|root,2Z9AM@2|Bacteria,4NJYJ@976|Bacteroidetes,1I0ZC@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1796151_5 1237149.C900_03792 1.635e-96 325.0 COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,47NWC@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF3078) - - - - - - - - - - - - DUF3078 DYD2_k127_1796151_8 1121904.ARBP01000012_gene1264 1.731e-39 152.0 COG0517@1|root,COG0517@2|Bacteria,4NNFS@976|Bacteroidetes 976|Bacteroidetes S CBS domain - - - - - - - - - - - - CBS DYD2_k127_1796151_6 468059.AUHA01000002_gene847 2.315e-86 292.0 COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,1IXDR@117747|Sphingobacteriia 976|Bacteroidetes O Peptide methionine sulfoxide reductase msrA1 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR DYD2_k127_1796151_3 566466.NOR53_2351 1.165e-177 568.0 COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,1RP3N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S amidohydrolase - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 DYD2_k127_1796151_2 929556.Solca_0644 1.584e-180 570.0 COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,1IP6F@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the agmatine deiminase family aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph DYD2_k127_1796151_4 1267211.KI669560_gene1949 2.432e-165 522.0 COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1IPIY@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase pabB - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase DYD2_k127_1796151_0 1288963.ADIS_1943 0.0 1286.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia 976|Bacteroidetes C FAD linked oxidases, C-terminal domain - - - - - - - - - - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8 DYD2_k127_1796151_1 1288963.ADIS_2079 5.208e-213 675.0 COG1620@1|root,COG1620@2|Bacteria,4NHVH@976|Bacteroidetes,47Q1C@768503|Cytophagia 976|Bacteroidetes C L-lactate permease lctP - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm DYD2_k127_1796151_7 595460.RRSWK_03194 8.633e-77 263.0 COG2239@1|root,COG2239@2|Bacteria,2IYCZ@203682|Planctomycetes 203682|Planctomycetes P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD2_k127_1796151_9 926569.ANT_24720 1.31e-14 78.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi 200795|Chloroflexi T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,GAF_3,HATPase_c,HisKA_3 DYD2_k127_1810803_8 929703.KE386491_gene364 3.094e-97 323.0 COG3279@1|root,COG3279@2|Bacteria,4NIXU@976|Bacteroidetes,47M0C@768503|Cytophagia 976|Bacteroidetes T LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg DYD2_k127_1810803_7 926549.KI421517_gene2842 6.565e-129 421.0 COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,47ME5@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase DYD2_k127_1810803_2 1279009.ADICEAN_01589 1.842e-267 853.0 COG4206@1|root,COG4206@2|Bacteria,4PKNV@976|Bacteroidetes,47XXQ@768503|Cytophagia 976|Bacteroidetes H Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug DYD2_k127_1810803_14 313603.FB2170_03675 6.035e-43 168.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia,2PHFA@252356|Maribacter 976|Bacteroidetes T Universal stress protein family - - - - - - - - - - - - Usp DYD2_k127_1810803_10 1121904.ARBP01000002_gene6683 1.059e-70 246.0 COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,47NRE@768503|Cytophagia 976|Bacteroidetes P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC DYD2_k127_1810803_6 391596.PBAL39_01712 1.717e-138 447.0 COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,1IQZS@117747|Sphingobacteriia 976|Bacteroidetes E PFAM peptidase T2 asparaginase 2 aspG GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 ko:K01444,ko:K13051 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 DYD2_k127_1810803_12 643867.Ftrac_2275 1.878e-59 211.0 COG0791@1|root,COG0791@2|Bacteria,4NSZJ@976|Bacteroidetes,47PEH@768503|Cytophagia 976|Bacteroidetes M Cell wall-associated hydrolase (invasion-associated protein) spr - - ko:K13695 - - - - ko00000,ko01002 - - - LysM,NLPC_P60 DYD2_k127_1810803_3 643867.Ftrac_2276 2.371e-210 663.0 COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia 976|Bacteroidetes C FAD linked oxidases, C-terminal domain glcD - 1.1.2.4,1.1.3.15 ko:K00102,ko:K00104 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 - R00197,R00475 RC00042,RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 DYD2_k127_1810803_1 1237149.C900_01149 1.094e-274 857.0 COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia 976|Bacteroidetes E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 DYD2_k127_1810803_0 1279009.ADICEAN_01593 1.16e-277 861.0 COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,47MT0@768503|Cytophagia 976|Bacteroidetes J PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C DYD2_k127_1810803_11 1121896.JMLU01000028_gene2810 7.523e-62 216.0 COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,1I250@117743|Flavobacteriia,2P0IC@237|Flavobacterium 976|Bacteroidetes L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp DYD2_k127_1810803_5 925409.KI911562_gene1748 3.72e-173 551.0 COG3488@1|root,COG3488@2|Bacteria,4NGBS@976|Bacteroidetes 976|Bacteroidetes C Thiol oxidoreductase - - - - - - - - - - - - DHOR DYD2_k127_1810803_15 1121904.ARBP01000035_gene1753 7.75e-35 138.0 COG0723@1|root,COG0723@2|Bacteria,4NJPJ@976|Bacteroidetes 976|Bacteroidetes C Rieske [2Fe-2S] domain - - 1.10.9.1 ko:K02636 ko00195,ko01100,map00195,map01100 M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske DYD2_k127_1810803_4 1123276.KB893311_gene3229 7.718e-174 553.0 COG1730@1|root,COG1730@2|Bacteria 2|Bacteria O sister chromatid segregation - - - - - - - - - - - - - DYD2_k127_1810803_18 1223410.KN050846_gene1075 1.9e-23 103.0 2AMB1@1|root,33CB8@2|Bacteria,4P882@976|Bacteroidetes,1IAZ6@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1810803_16 307480.IW16_13290 1.703e-26 121.0 COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,1HWW5@117743|Flavobacteriia,3ZPS4@59732|Chryseobacterium 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein pchR - - - - - - - - - - - HTH_18 DYD2_k127_1810803_9 471854.Dfer_1198 4.521e-89 302.0 COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47PEN@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD2_k127_1810803_13 1123276.KB893252_gene3675 4.25e-56 203.0 28ME7@1|root,2ZARX@2|Bacteria,4P47D@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - Hemerythrin DYD2_k127_1810803_17 1121904.ARBP01000001_gene5650 1.378e-23 109.0 COG3209@1|root,COG3209@2|Bacteria,4NWG7@976|Bacteroidetes,47VGU@768503|Cytophagia 976|Bacteroidetes M COG3209 Rhs family protein - - - - - - - - - - - - - DYD2_k127_1828399_2 1189619.pgond44_14073 1.741e-75 288.0 COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,TPR_12,TPR_7 DYD2_k127_1828399_0 1089550.ATTH01000001_gene1101 1.469e-156 538.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y DYD2_k127_1828399_1 1492737.FEM08_05140 1.417e-135 441.0 COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia,2NTEI@237|Flavobacterium 976|Bacteroidetes T Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Reg_prop,Y_Y_Y DYD2_k127_1889445_0 1121875.KB907550_gene639 0.0 1274.0 COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3 DYD2_k127_1889445_3 1121887.AUDK01000010_gene1413 1.381e-36 139.0 2C82G@1|root,32RK9@2|Bacteria,4NSXV@976|Bacteroidetes,1I466@117743|Flavobacteriia,2NX9M@237|Flavobacterium 976|Bacteroidetes S Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 DYD2_k127_1889445_1 1101191.KI912577_gene1006 1.311e-64 224.0 COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria,1JSFC@119045|Methylobacteriaceae 28211|Alphaproteobacteria O PFAM OsmC family protein MA20_23315 - - - - - - - - - - - OsmC DYD2_k127_1889445_2 487796.Flav2ADRAFT_0926 3.242e-37 149.0 2C3TU@1|root,2ZBKB@2|Bacteria,4NMMF@976|Bacteroidetes,1I1HI@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1889445_4 1484460.JSWG01000008_gene1932 0.0006171 45.0 2C3TU@1|root,2ZBKB@2|Bacteria,4NMMF@976|Bacteroidetes,1I1HI@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1891744_7 1237149.C900_00190 4.498e-198 625.0 COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,47JQ0@768503|Cytophagia 976|Bacteroidetes F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt DYD2_k127_1891744_41 1237149.C900_00191 6.963e-36 139.0 COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes,47R73@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS DYD2_k127_1891744_26 926556.Echvi_4630 4.611e-81 271.0 COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,47P99@768503|Cytophagia 976|Bacteroidetes P Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR DYD2_k127_1891744_0 1237149.C900_00193 0.0 1150.0 COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,47JQ8@768503|Cytophagia 976|Bacteroidetes KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS DYD2_k127_1891744_16 1237149.C900_00194 5.371e-141 460.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,47KTD@768503|Cytophagia 976|Bacteroidetes O Trigger factor tig - - ko:K03545 - - - - ko00000 - - - Trigger_C,Trigger_N DYD2_k127_1891744_21 1237149.C900_00195 4.209e-108 353.0 COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,47K60@768503|Cytophagia 976|Bacteroidetes OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease DYD2_k127_1891744_4 1237149.C900_00196 1.238e-223 697.0 COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,47JDR@768503|Cytophagia 976|Bacteroidetes O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX DYD2_k127_1891744_18 313606.M23134_05530 1.906e-120 397.0 COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,47JDC@768503|Cytophagia 976|Bacteroidetes M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB DYD2_k127_1891744_28 1124780.ANNU01000019_gene1745 6.729e-72 244.0 COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,47PVC@768503|Cytophagia 976|Bacteroidetes H TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS DYD2_k127_1891744_12 1237149.C900_00202 9.352e-162 514.0 COG0451@1|root,COG0451@2|Bacteria,4NIZG@976|Bacteroidetes,47KEK@768503|Cytophagia 976|Bacteroidetes GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose hldD - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase DYD2_k127_1891744_9 1120968.AUBX01000010_gene1260 1.589e-185 614.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia 976|Bacteroidetes O PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - - - - - - - - - - PKD,P_proprotein,Peptidase_S8,fn3 DYD2_k127_1891744_46 616991.JPOO01000003_gene2634 4.427e-06 54.0 COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia 976|Bacteroidetes O Belongs to the peptidase S8 family - - - - - - - - - - - - MAM,Peptidase_S8,fn3 DYD2_k127_1891744_5 1237149.C900_04960 2.201e-218 694.0 COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47MTM@768503|Cytophagia 976|Bacteroidetes MU Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40,TPR_16,TPR_2,TPR_8 DYD2_k127_1891744_25 1150600.ADIARSV_1390 5.239e-86 288.0 COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM DYD2_k127_1891744_19 1237149.C900_04961 7.035e-113 371.0 COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,47K0S@768503|Cytophagia 976|Bacteroidetes F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C DYD2_k127_1891744_2 1237149.C900_04963 8e-323 994.0 COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,47K4P@768503|Cytophagia 976|Bacteroidetes M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C DYD2_k127_1891744_44 153721.MYP_3695 7.2e-07 56.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - DYD2_k127_1891744_30 1237149.C900_04968 2.158e-62 220.0 COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,47QV5@768503|Cytophagia 976|Bacteroidetes S Acyl carrier protein phosphodiesterase acpH - - - - - - - - - - - ACP_PD DYD2_k127_1891744_35 1279009.ADICEAN_03330 2.075e-51 184.0 2BXI1@1|root,32R1C@2|Bacteria,4NR9I@976|Bacteroidetes,47QU5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1891744_14 643867.Ftrac_1576 3.599e-147 473.0 COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,47JR7@768503|Cytophagia 976|Bacteroidetes H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD2_k127_1891744_33 313598.MED152_09675 4.852e-54 194.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,1I1YS@117743|Flavobacteriia,3VWGU@52959|Polaribacter 976|Bacteroidetes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mce - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 DYD2_k127_1891744_31 643867.Ftrac_1574 4.639e-58 204.0 2BJ0K@1|root,32D95@2|Bacteria,4NQN9@976|Bacteroidetes,47QR4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1891744_32 1279009.ADICEAN_03325 1.294e-54 192.0 COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,47QAX@768503|Cytophagia 976|Bacteroidetes S Belongs to the HesB IscA family iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn DYD2_k127_1891744_29 1237149.C900_04977 4.792e-70 239.0 COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,47PT2@768503|Cytophagia 976|Bacteroidetes J Endoribonuclease L-PSP - - 3.5.99.5 ko:K15067 ko00380,map00380 - R03887 RC01015 ko00000,ko00001,ko01000 - - - Ribonuc_L-PSP DYD2_k127_1891744_38 1356852.N008_14395 3.06e-47 179.0 COG5266@1|root,COG5266@2|Bacteria,4NQ8X@976|Bacteroidetes,47QXS@768503|Cytophagia 976|Bacteroidetes P Domain of unknown function (DUF4198) - - - - - - - - - - - - DUF4198 DYD2_k127_1891744_8 1237149.C900_04979 6.99e-186 590.0 COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia 976|Bacteroidetes E Belongs to the peptidase M24B family pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 DYD2_k127_1891744_6 1237149.C900_03677 3.21e-199 625.0 COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,47JEY@768503|Cytophagia 976|Bacteroidetes J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT DYD2_k127_1891744_17 1237149.C900_03678 7.077e-126 412.0 COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,47JHT@768503|Cytophagia 976|Bacteroidetes S Permease YjgP YjgQ family lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ DYD2_k127_1891744_23 1237149.C900_03679 4.125e-95 320.0 COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,47JNH@768503|Cytophagia 976|Bacteroidetes EG PFAM EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_1891744_24 1124780.ANNU01000037_gene145 2.637e-92 310.0 COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,47JG4@768503|Cytophagia 976|Bacteroidetes I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD2_k127_1891744_13 1124780.ANNU01000037_gene144 9.831e-148 471.0 COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,47KZ9@768503|Cytophagia 976|Bacteroidetes I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_1891744_20 1237149.C900_03683 1.151e-109 360.0 COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47MMI@768503|Cytophagia 976|Bacteroidetes M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race DYD2_k127_1891744_15 1237149.C900_03685 4.009e-143 478.0 COG5002@1|root,COG5002@2|Bacteria,4PKMH@976|Bacteroidetes,47XWJ@768503|Cytophagia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_9,TPR_12 DYD2_k127_1891744_1 1237149.C900_03692 1e-323 998.0 COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,47JRN@768503|Cytophagia 976|Bacteroidetes F PFAM Glutamine amidotransferase, class-II purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7 DYD2_k127_1891744_11 1237149.C900_05868 1.042e-163 520.0 COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia 976|Bacteroidetes M PFAM glycosyl transferase family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 DYD2_k127_1891744_39 1267211.KI669560_gene1791 4.464e-45 168.0 COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia 976|Bacteroidetes S EVE domain - - - - - - - - - - - - EVE DYD2_k127_1891744_40 929562.Emtol_4017 6.696e-39 164.0 28KQM@1|root,2ZA8D@2|Bacteria,4NG3K@976|Bacteroidetes,47XIW@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1891744_22 1237149.C900_05864 3.836e-107 366.0 28KQM@1|root,2ZA8D@2|Bacteria,4NH80@976|Bacteroidetes,47JWY@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1891744_27 1237149.C900_05853 1.07e-77 263.0 COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,47MTK@768503|Cytophagia 976|Bacteroidetes F Pyrimidine operon attenuation protein uracil phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran DYD2_k127_1891744_10 1120965.AUBV01000006_gene2422 6.26e-170 536.0 COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,47KS2@768503|Cytophagia 976|Bacteroidetes F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD2_k127_1891744_3 1237149.C900_05850 7.051e-240 747.0 COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,47K1B@768503|Cytophagia 976|Bacteroidetes E Cystathionine beta-synthase - - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP DYD2_k127_1891744_36 1237149.C900_01882 3.48e-51 196.0 COG2885@1|root,COG2885@2|Bacteria 2|Bacteria M chlorophyll binding - - - - - - - - - - - - OmpA DYD2_k127_1891744_37 1237149.C900_01882 1.221e-50 201.0 COG2885@1|root,COG2885@2|Bacteria 2|Bacteria M chlorophyll binding - - - - - - - - - - - - OmpA DYD2_k127_1891744_42 1123008.KB905693_gene1145 2.6e-22 100.0 COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,2FNUH@200643|Bacteroidia,22W9J@171551|Porphyromonadaceae 976|Bacteroidetes M Penicillin-Binding Protein C-terminus Family pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase DYD2_k127_1891744_34 1124780.ANNU01000010_gene3751 6.793e-54 194.0 COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,47P5J@768503|Cytophagia 976|Bacteroidetes M Mechanosensitive ion channel - - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel DYD2_k127_1971513_0 1123057.P872_15440 4.096e-216 678.0 COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia 976|Bacteroidetes S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD2_k127_1971513_3 269798.CHU_0498 1.014e-19 89.0 2FKSJ@1|root,34CD3@2|Bacteria,4P89S@976|Bacteroidetes,47WSU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1971513_1 760192.Halhy_5684 2.426e-80 273.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1ISDK@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - - - - - - - - - - HTH_18 DYD2_k127_1971513_2 1086011.HJ01_03461 5.858e-27 113.0 COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,4PKV1@976|Bacteroidetes,1IKKI@117743|Flavobacteriia,2P0QX@237|Flavobacterium 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - CHASE3,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD2_k127_1976973_25 1237149.C900_00059 2.221e-56 206.0 28NZH@1|root,2ZBWE@2|Bacteria,4NM7N@976|Bacteroidetes,47V8T@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1976973_31 760192.Halhy_1328 2.292e-33 137.0 COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1IT9I@117747|Sphingobacteriia 976|Bacteroidetes S PFAM YceI-like domain - - - - - - - - - - - - YceI DYD2_k127_1976973_9 866536.Belba_1289 1.572e-206 650.0 2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,47U5A@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1976973_29 1279009.ADICEAN_03082 2.17e-34 139.0 COG2353@1|root,COG2353@2|Bacteria,4NTB0@976|Bacteroidetes,47VJ0@768503|Cytophagia 976|Bacteroidetes S Pfam YceI-like domain - - - - - - - - - - - - YceI DYD2_k127_1976973_30 1123057.P872_05020 3.951e-34 138.0 COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,47RR5@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI DYD2_k127_1976973_5 1237149.C900_00272 1.752e-240 749.0 COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,47JRV@768503|Cytophagia 976|Bacteroidetes E PFAM Pyridoxal-dependent decarboxylase, C-terminal sheet domain speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC DYD2_k127_1976973_10 1237149.C900_00273 2.541e-131 425.0 COG0010@1|root,COG0010@2|Bacteria,4NE26@976|Bacteroidetes,47N30@768503|Cytophagia 976|Bacteroidetes E Belongs to the arginase family rocF - 3.5.3.1,3.5.3.11 ko:K01476,ko:K01480 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00133,M00134 R00551,R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD2_k127_1976973_38 641524.ADICYQ_5705 1.217e-15 85.0 2EU2T@1|root,33MJR@2|Bacteria,4NZIZ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1976973_14 1237149.C900_00276 4.462e-116 377.0 COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,47M06@768503|Cytophagia 976|Bacteroidetes O Deoxyhypusine synthase dys1 - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS DYD2_k127_1976973_24 1250278.JQNQ01000001_gene1440 6.747e-58 201.0 COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1HXQG@117743|Flavobacteriia 976|Bacteroidetes O Deoxyhypusine synthase dys1 - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS DYD2_k127_1976973_3 1237149.C900_00279 3e-263 823.0 COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,47K91@768503|Cytophagia 976|Bacteroidetes J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d DYD2_k127_1976973_22 1124780.ANNU01000024_gene3056 7.725e-68 235.0 COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,47P7U@768503|Cytophagia 976|Bacteroidetes O Belongs to the glutathione peroxidase family gpx1 - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx DYD2_k127_1976973_15 1237149.C900_00280 2.341e-111 366.0 COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,47JDA@768503|Cytophagia 976|Bacteroidetes H Belongs to the MenA family. Type 1 subfamily menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD2_k127_1976973_21 1237149.C900_00541 4.177e-71 249.0 COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp DYD2_k127_1976973_6 1237149.C900_03383 3.86e-222 713.0 COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia 976|Bacteroidetes P ATPase, P-type (transporting), HAD superfamily, subfamily IC ccoI - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase DYD2_k127_1976973_40 1408433.JHXV01000049_gene1902 1.075e-12 70.0 COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia,2PB7Y@246874|Cryomorphaceae 976|Bacteroidetes P TIGRFAM cytochrome oxidase maturation protein, cbb3-type ccoS - - - - - - - - - - - FixS DYD2_k127_1976973_16 655815.ZPR_3640 1.392e-102 342.0 COG0111@1|root,COG0111@2|Bacteria,4NE9J@976|Bacteroidetes,1HZ5Z@117743|Flavobacteriia 976|Bacteroidetes EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ghrA - 1.1.1.79,1.1.1.81 ko:K12972 ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120 - R00465,R01388,R01392,R02527 RC00031,RC00042,RC00670 ko00000,ko00001,ko01000 - - - 2-Hacid_dh_C DYD2_k127_1976973_1 234267.Acid_1953 0.0 1142.0 COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria 57723|Acidobacteria S cellulose binding - - - - - - - - - - - - - DYD2_k127_1976973_19 1123248.KB893348_gene142 2.133e-81 281.0 2DBQG@1|root,2ZADX@2|Bacteria,4PI3K@976|Bacteroidetes,1IUKI@117747|Sphingobacteriia 976|Bacteroidetes S Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 DYD2_k127_1976973_4 1392498.JQLH01000001_gene1026 4.617e-245 771.0 COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1IC5Y@117743|Flavobacteriia,2PIIJ@252356|Maribacter 976|Bacteroidetes S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD2_k127_1976973_20 487796.Flav2ADRAFT_0084 1.156e-75 263.0 COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,1I5ZB@117743|Flavobacteriia 976|Bacteroidetes S Alpha/beta hydrolase family - - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD2_k127_1976973_26 313595.P700755_002432 8.067e-51 200.0 2CW3Z@1|root,32SYZ@2|Bacteria,4NTGZ@976|Bacteroidetes,1I4XD@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1976973_0 1237149.C900_03366 0.0 1220.0 COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia 976|Bacteroidetes C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1,FixO DYD2_k127_1976973_41 641526.ADIWIN_2969 2.679e-06 51.0 2E7S7@1|root,3327D@2|Bacteria,4NUQB@976|Bacteroidetes,1I51Y@117743|Flavobacteriia 976|Bacteroidetes S PFAM Cbb3-type cytochrome oxidase component FixQ ccoQ - - - - - - - - - - - FixQ DYD2_k127_1976973_18 1237149.C900_03364 2.552e-82 283.0 COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,47PY8@768503|Cytophagia 976|Bacteroidetes C TIGRFAM cytochrome c oxidase, cbb3-type, subunit III ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N DYD2_k127_1976973_8 1237149.C900_03363 2.857e-214 674.0 COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia 976|Bacteroidetes C TIGRFAM cytochrome c oxidase accessory protein ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C DYD2_k127_1976973_37 641524.ADICYQ_3658 1.129e-17 88.0 COG5456@1|root,COG5456@2|Bacteria,4NUZC@976|Bacteroidetes,47YSU@768503|Cytophagia 976|Bacteroidetes P PFAM FixH ccoH - - - - - - - - - - - FixH DYD2_k127_1976973_32 491205.JARQ01000005_gene1709 1.001e-31 133.0 COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,1HXIX@117743|Flavobacteriia,3ZPJG@59732|Chryseobacterium 976|Bacteroidetes S Cytochrome C biogenesis protein - - - ko:K09792 - - - - ko00000 - - - DsbD_2 DYD2_k127_1976973_17 1237149.C900_00284 1.16e-90 306.0 COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp DYD2_k127_1976973_39 743525.TSC_c20290 1.629e-15 86.0 COG0484@1|root,COG0484@2|Bacteria,1WIGZ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O DnaJ-class molecular chaperone with C-terminal Zn finger domain dnaJ2 - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C DYD2_k127_1976973_28 641524.ADICYQ_1053 9.977e-43 158.0 COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,47R38@768503|Cytophagia 976|Bacteroidetes J PFAM translation initiation factor SUI1 - - - ko:K03113 ko03013,map03013 - - - ko00000,ko00001,ko03012 - - - SUI1 DYD2_k127_1976973_11 1121904.ARBP01000019_gene2809 4.551e-130 425.0 COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,47UBF@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 DYD2_k127_1976973_23 331113.SNE_A07170 4.842e-60 218.0 COG1597@1|root,COG1597@2|Bacteria,2JH3J@204428|Chlamydiae 204428|Chlamydiae I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat DYD2_k127_1976973_34 1237149.C900_05730 2.019e-30 122.0 COG0236@1|root,COG0236@2|Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD2_k127_1976973_12 1121904.ARBP01000012_gene1248 7.406e-119 396.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c DYD2_k127_1976973_7 1237149.C900_05728 5.177e-222 696.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD2_k127_1976973_35 153721.MYP_1307 2.101e-26 119.0 2CGN1@1|root,32S49@2|Bacteria,4NQPU@976|Bacteroidetes,47R8D@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_1976973_13 1237149.C900_05722 8.14e-117 381.0 COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,47JQJ@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 DYD2_k127_1976973_2 1237149.C900_05721 0.0 1027.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,47KKF@768503|Cytophagia 976|Bacteroidetes O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD2_k127_1976973_27 1237149.C900_05720 7.447e-48 174.0 COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia 976|Bacteroidetes S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD2_k127_2015029_4 446462.Amir_5842 0.0004217 42.0 COG1028@1|root,COG1028@2|Bacteria,2GWHQ@201174|Actinobacteria,4E590@85010|Pseudonocardiales 201174|Actinobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 DYD2_k127_2015029_1 761193.Runsl_0923 1.306e-291 917.0 COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,47N2Q@768503|Cytophagia 976|Bacteroidetes E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 DYD2_k127_2015029_2 1237149.C900_04701 1.043e-73 254.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD2_k127_2015029_0 1189619.pgond44_02448 0.0 1052.0 COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1I7D0@117743|Flavobacteriia,4C476@83612|Psychroflexus 976|Bacteroidetes S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD2_k127_2015029_3 1122176.KB903569_gene3490 7.37e-57 202.0 2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes,1ITQ6@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2041716_3 1286632.P278_12280 1.676e-46 169.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD2_k127_2041716_0 926556.Echvi_3727 1.073e-316 990.0 COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,47NF0@768503|Cytophagia 976|Bacteroidetes C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase DYD2_k127_2041716_4 700598.Niako_0627 2.538e-32 132.0 COG0500@1|root,COG0500@2|Bacteria,4PN8K@976|Bacteroidetes 976|Bacteroidetes H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 DYD2_k127_2041716_1 700598.Niako_0825 8.667e-295 923.0 COG1361@1|root,COG1472@1|root,COG1361@2|Bacteria,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IR7S@117747|Sphingobacteriia 976|Bacteroidetes G Fibronectin type III-like domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C DYD2_k127_2041716_2 1408473.JHXO01000005_gene1676 3.853e-66 232.0 COG1051@1|root,COG1051@2|Bacteria,4PMRX@976|Bacteroidetes 976|Bacteroidetes F NUDIX domain - - - - - - - - - - - - NUDIX DYD2_k127_2078279_5 1120965.AUBV01000001_gene3449 3.698e-81 285.0 COG0507@1|root,COG0507@2|Bacteria,4NF6J@976|Bacteroidetes,47JK1@768503|Cytophagia 976|Bacteroidetes L PIF1-like helicase - - - - - - - - - - - - HTH_40,Herpes_Helicase,PIF1,UvrD_C_2 DYD2_k127_2078279_1 1121904.ARBP01000002_gene6913 4.097e-197 618.0 COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,47JHR@768503|Cytophagia 976|Bacteroidetes E PFAM glutamine synthetase catalytic region glnII - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N DYD2_k127_2078279_0 926562.Oweho_2108 8.147e-228 742.0 COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia,2PBG6@246874|Cryomorphaceae 976|Bacteroidetes S PKD domain - - - - - - - - - - - - DUF11,PKD DYD2_k127_2078279_9 1121895.Q765_20730 3.557e-09 71.0 COG1345@1|root,COG2374@1|root,COG3210@1|root,COG1345@2|Bacteria,COG2374@2|Bacteria,COG3210@2|Bacteria,4NFVP@976|Bacteroidetes,1IIIJ@117743|Flavobacteriia,2P0E0@237|Flavobacterium 976|Bacteroidetes N Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - DUF3494,LTD DYD2_k127_2078279_2 388413.ALPR1_13974 8.878e-140 475.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2078279_8 388413.ALPR1_13979 9.149e-36 139.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QZJ@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR DYD2_k127_2078279_4 1121904.ARBP01000002_gene6955 7.181e-106 347.0 COG1741@1|root,COG1741@2|Bacteria,4NGJ5@976|Bacteroidetes,47N6P@768503|Cytophagia 976|Bacteroidetes S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin DYD2_k127_2078279_3 929556.Solca_0019 9.985e-116 379.0 COG1741@1|root,COG1741@2|Bacteria,4NN4X@976|Bacteroidetes,1J089@117747|Sphingobacteriia 976|Bacteroidetes S Pirin C-terminal cupin domain - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C DYD2_k127_2078279_6 203124.Tery_3562 7.296e-54 195.0 COG0778@1|root,COG0778@2|Bacteria,1G42X@1117|Cyanobacteria,1HFEV@1150|Oscillatoriales 1117|Cyanobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase DYD2_k127_2078279_7 1189612.A33Q_3288 2.048e-52 188.0 COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,47QRI@768503|Cytophagia 976|Bacteroidetes S Divergent 4Fe-4S mono-cluster - - - - - - - - - - - - Fer4_19,zf-CDGSH DYD2_k127_2091825_6 941449.dsx2_0034 1.722e-43 161.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NAQ@68525|delta/epsilon subdivisions,2WJPX@28221|Deltaproteobacteria,2M845@213115|Desulfovibrionales 28221|Deltaproteobacteria BQ PFAM Histone deacetylase - - - - - - - - - - - - Acetyltransf_1,Hist_deacetyl DYD2_k127_2091825_2 1047013.AQSP01000037_gene1323 2.521e-100 336.0 COG1171@1|root,COG1171@2|Bacteria,2NQCM@2323|unclassified Bacteria 2|Bacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA tdcB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_2091825_1 886377.Murru_3257 1.073e-129 437.0 COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia 976|Bacteroidetes P H( )-stimulated, divalent metal cation uptake system mntH - - - - - - - - - - - Nramp DYD2_k127_2091825_4 867900.Celly_3011 2.236e-75 277.0 COG1540@1|root,COG1540@2|Bacteria,4NJ86@976|Bacteroidetes,1HY57@117743|Flavobacteriia,1F99Z@104264|Cellulophaga 976|Bacteroidetes S PFAM Uncharacterised protein family UPF0271, LamB YcsF - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF DYD2_k127_2091825_5 1178825.ALIH01000002_gene921 8.763e-71 247.0 COG2049@1|root,COG2049@2|Bacteria,4NMNT@976|Bacteroidetes,1I1C1@117743|Flavobacteriia 976|Bacteroidetes E Allophanate hydrolase subunit 1 kipI - - ko:K06351 - - - - ko00000 - - - CT_C_D DYD2_k127_2091825_3 1250278.JQNQ01000001_gene3197 9.229e-77 266.0 COG1984@1|root,COG1984@2|Bacteria,4NGIV@976|Bacteroidetes,1HXTB@117743|Flavobacteriia 976|Bacteroidetes E Allophanate hydrolase subunit 2 - - - ko:K06350 - - - - ko00000 - - - CT_A_B DYD2_k127_2091825_0 886377.Murru_3230 3.853e-196 635.0 COG4188@1|root,COG4188@2|Bacteria,4NKC2@976|Bacteroidetes,1HZ4A@117743|Flavobacteriia 976|Bacteroidetes S Pkd domain containing protein - - - - - - - - - - - - Chlorophyllase2 DYD2_k127_2091825_7 1120966.AUBU01000006_gene3494 5.575e-05 51.0 28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,47SGM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2126037_6 1123277.KB893217_gene4470 4.015e-77 267.0 COG2382@1|root,COG2382@2|Bacteria,4NI86@976|Bacteroidetes,47NJ2@768503|Cytophagia 976|Bacteroidetes P Putative esterase - - - - - - - - - - - - Esterase DYD2_k127_2126037_4 714943.Mucpa_3723 1.511e-102 338.0 COG2382@1|root,COG2382@2|Bacteria,4NGIA@976|Bacteroidetes,1IQTD@117747|Sphingobacteriia 976|Bacteroidetes P Putative esterase - - - - - - - - - - - - Abhydrolase_1,Esterase DYD2_k127_2126037_2 929703.KE386491_gene1913 5.243e-152 486.0 COG0189@1|root,COG0189@2|Bacteria,4NFK1@976|Bacteroidetes,47JY9@768503|Cytophagia 976|Bacteroidetes HJ Glutathione synthase - - - - - - - - - - - - - DYD2_k127_2126037_1 1408813.AYMG01000003_gene2900 1.232e-177 562.0 COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,1IRMY@117747|Sphingobacteriia 976|Bacteroidetes S ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity ybdK - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 DYD2_k127_2126037_5 471854.Dfer_0435 6.778e-95 318.0 COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,47NFG@768503|Cytophagia 976|Bacteroidetes F Glutamine amidotransferase class-I - - - - - - - - - - - - GATase DYD2_k127_2126037_3 1123277.KB893217_gene4506 2.933e-127 418.0 COG2308@1|root,COG2308@2|Bacteria,4NG4D@976|Bacteroidetes,47K1S@768503|Cytophagia 976|Bacteroidetes S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - DYD2_k127_2126037_0 929556.Solca_2890 2.73e-179 572.0 COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1IQJT@117747|Sphingobacteriia 976|Bacteroidetes V Mate efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD2_k127_2126037_8 1237149.C900_02258 3.519e-63 224.0 2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,47RS3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2126037_7 1237149.C900_02256 8.971e-70 240.0 COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,47K5Q@768503|Cytophagia 976|Bacteroidetes F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin DYD2_k127_2128087_35 394503.Ccel_2037 3.284e-05 48.0 COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,36IRR@31979|Clostridiaceae 186801|Clostridia NT Chemotaxis protein cheY cheY - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg DYD2_k127_2128087_23 1121904.ARBP01000004_gene1044 7.133e-52 194.0 COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,47TQU@768503|Cytophagia 976|Bacteroidetes T Stage II sporulation protein E (SpoIIE) - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y DYD2_k127_2128087_29 1237149.C900_03174 2.25e-35 139.0 COG5608@1|root,COG5608@2|Bacteria,4NVQ5@976|Bacteroidetes 976|Bacteroidetes S Late embryogenesis abundant protein - - - - - - - - - - - - LEA_2 DYD2_k127_2128087_6 1317122.ATO12_03825 5.386e-171 542.0 COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1HYFP@117743|Flavobacteriia,2YIVD@290174|Aquimarina 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD2_k127_2128087_21 1469607.KK073768_gene351 8.453e-62 227.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales 1117|Cyanobacteria O Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_8,Trypsin_2 DYD2_k127_2128087_34 315730.BcerKBAB4_2413 1.514e-08 63.0 COG2318@1|root,COG2318@2|Bacteria,1V70V@1239|Firmicutes,4HJAI@91061|Bacilli,1ZIMU@1386|Bacillus 91061|Bacilli S DinB superfamily - - - - - - - - - - - - DinB_2 DYD2_k127_2128087_2 1237149.C900_03155 0.0 1021.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia 976|Bacteroidetes E PFAM Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 DYD2_k127_2128087_18 1237149.C900_05707 2.178e-68 237.0 COG2353@1|root,COG2353@2|Bacteria,4NMWH@976|Bacteroidetes,47PZ0@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0312 family yceI - - - - - - - - - - - YceI DYD2_k127_2128087_9 109760.SPPG_04804T0 5.384e-130 423.0 COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi 4751|Fungi Q Dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD2_k127_2128087_5 1121904.ARBP01000005_gene4643 5.929e-207 670.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47P60@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2128087_11 1237149.C900_05167 1.749e-106 355.0 COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,47N7G@768503|Cytophagia 976|Bacteroidetes O Gliding motility protein, GldB gldB - - - - - - - - - - - - DYD2_k127_2128087_12 1121373.KB903620_gene2201 1.239e-104 354.0 COG0438@1|root,COG0438@2|Bacteria,4NI16@976|Bacteroidetes,47KFJ@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 DYD2_k127_2128087_14 1237149.C900_01514 2.754e-91 304.0 COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,47KW3@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD2_k127_2128087_0 1237149.C900_01516 0.0 1429.0 COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,47JVJ@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA1 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - AAA_21,ABC_tran DYD2_k127_2128087_32 1296415.JACC01000027_gene1352 4.277e-17 88.0 COG4319@1|root,COG4319@2|Bacteria,4PMRD@976|Bacteroidetes,1I1CU@117743|Flavobacteriia,2YI8V@290174|Aquimarina 976|Bacteroidetes S SnoaL-like domain - - - - - - - - - - - - DUF4440 DYD2_k127_2128087_17 1270193.JARP01000005_gene3856 1.094e-73 252.0 COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1I190@117743|Flavobacteriia,2NUTM@237|Flavobacterium 976|Bacteroidetes S YeeE YedE family protein - - - ko:K07112 - - - - ko00000 - - - Sulf_transp DYD2_k127_2128087_25 1121859.KB890739_gene2466 4.98e-51 187.0 COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes 976|Bacteroidetes S Transporter - - - ko:K07112 - - - - ko00000 - - - Sulf_transp DYD2_k127_2128087_3 1237149.C900_01521 4.248e-229 715.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47MQD@768503|Cytophagia 976|Bacteroidetes E Belongs to the Glu Leu Phe Val dehydrogenases family gdh GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009986,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD2_k127_2128087_27 1237149.C900_03640 1.937e-40 151.0 COG5470@1|root,COG5470@2|Bacteria,4NUEC@976|Bacteroidetes,47V9R@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 DYD2_k127_2128087_24 1237149.C900_03767 1.297e-51 186.0 COG2839@1|root,COG2839@2|Bacteria,4NNIY@976|Bacteroidetes,47R24@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF456) - - - ko:K09793 - - - - ko00000 - - - DUF456 DYD2_k127_2128087_8 1121875.KB907547_gene3391 6.772e-131 428.0 COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,1HWPK@117743|Flavobacteriia 976|Bacteroidetes EGP Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_2128087_33 216432.CA2559_01840 9.863e-15 81.0 29VAW@1|root,30GR0@2|Bacteria,4NPQQ@976|Bacteroidetes,1I2RU@117743|Flavobacteriia 976|Bacteroidetes S Domain of Unknown Function (DUF350) - - - - - - - - - - - - DUF350 DYD2_k127_2128087_28 391587.KAOT1_12027 6.776e-40 158.0 COG3672@1|root,COG3672@2|Bacteria 2|Bacteria O Periplasmic Protein - - - - - - - - - - - - Cu_amine_oxidN1,Peptidase_C93 DYD2_k127_2128087_22 1237149.C900_02735 4.041e-60 214.0 COG3762@1|root,COG3762@2|Bacteria 2|Bacteria S Membrane - - - ko:K08988 - - - - ko00000 - - - TPM_phosphatase DYD2_k127_2128087_16 1237149.C900_02736 8.307e-74 258.0 COG1512@1|root,COG1512@2|Bacteria,4NF4P@976|Bacteroidetes,47NDD@768503|Cytophagia 976|Bacteroidetes S Beta-propeller domains of methanol dehydrogenase type - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase DYD2_k127_2128087_4 1237149.C900_02738 5.66e-226 706.0 COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia 976|Bacteroidetes E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT DYD2_k127_2128087_13 1237149.C900_02739 6.509e-103 341.0 COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,47KG0@768503|Cytophagia 976|Bacteroidetes U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC DYD2_k127_2128087_20 1237149.C900_02740 4.841e-65 225.0 COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,47PQK@768503|Cytophagia 976|Bacteroidetes G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB DYD2_k127_2128087_19 1237149.C900_02741 2.641e-67 246.0 28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,47M3Y@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2128087_26 1237149.C900_02742 1.73e-40 153.0 COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,47Q35@768503|Cytophagia 976|Bacteroidetes J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA DYD2_k127_2128087_7 1237149.C900_02744 1.183e-141 461.0 COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,47M0Q@768503|Cytophagia 976|Bacteroidetes M ABC-type transport system involved in lipoprotein release permease component lolE_2 - - ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125,3.A.1.15.3,3.A.1.15.5 - - FtsX,MacB_PCD DYD2_k127_2128087_1 1237149.C900_02745 0.0 1289.0 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,47JVA@768503|Cytophagia 976|Bacteroidetes L PFAM Helicase conserved C-terminal domain - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N DYD2_k127_2128087_15 1237149.C900_02855 3.213e-74 259.0 COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,47MHM@768503|Cytophagia 976|Bacteroidetes M Lipid A biosynthesis acyltransferase waaM - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD2_k127_2128087_10 1237149.C900_02854 6.308e-119 387.0 COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,47JGN@768503|Cytophagia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD2_k127_2128087_30 743722.Sph21_1126 1.962e-21 94.0 COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1IQC6@117747|Sphingobacteriia 976|Bacteroidetes O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI DYD2_k127_2178999_15 1340434.AXVA01000003_gene1542 2.836e-28 118.0 COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,4HAE4@91061|Bacilli,1ZB60@1386|Bacillus 91061|Bacilli E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD2_k127_2178999_2 1250278.JQNQ01000001_gene2648 1.175e-212 686.0 COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,1HZ6R@117743|Flavobacteriia 976|Bacteroidetes P Outer membrane receptor for Fe3 -dicitrate fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_2178999_0 1121904.ARBP01000004_gene1059 2.093e-297 932.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_2178999_4 1185876.BN8_00887 1.616e-207 672.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MF5@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2178999_11 56110.Oscil6304_5587 1.276e-80 283.0 COG2848@1|root,COG2848@2|Bacteria,1G3IK@1117|Cyanobacteria 1117|Cyanobacteria S Uncharacterised ACR (DUF711) - - - ko:K09157 - - - - ko00000 - - - DUF711 DYD2_k127_2178999_10 1123248.KB893325_gene1224 3.969e-86 290.0 arCOG09454@1|root,30G4A@2|Bacteria,4NPSB@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2178999_6 1237149.C900_04641 4.195e-160 507.0 COG3000@1|root,COG3000@2|Bacteria,4NGQA@976|Bacteroidetes,47JWM@768503|Cytophagia 976|Bacteroidetes I Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase DYD2_k127_2178999_7 643867.Ftrac_3425 1.182e-149 502.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2178999_9 1519464.HY22_07155 1.29e-87 295.0 COG0217@1|root,COG0217@2|Bacteria,1FDKV@1090|Chlorobi 1090|Chlorobi K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg DYD2_k127_2178999_14 504472.Slin_1809 6.878e-40 156.0 COG1983@1|root,COG1983@2|Bacteria,4NS0M@976|Bacteroidetes,47QMV@768503|Cytophagia 976|Bacteroidetes KT Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 DYD2_k127_2178999_3 929556.Solca_3964 3.791e-210 672.0 COG1368@1|root,COG1368@2|Bacteria,4NIAA@976|Bacteroidetes,1IQ3M@117747|Sphingobacteriia 976|Bacteroidetes M sulfatase - - - - - - - - - - - - Sulfatase DYD2_k127_2178999_16 376686.Fjoh_2803 1.507e-05 49.0 COG3093@1|root,COG3093@2|Bacteria,4NSDG@976|Bacteroidetes,1I3X0@117743|Flavobacteriia,2NWPH@237|Flavobacterium 976|Bacteroidetes K DNA-binding protein - - - - - - - - - - - - HTH_3,Phage_CI_repr DYD2_k127_2178999_17 1223410.KN050846_gene1726 0.0002001 52.0 COG0589@1|root,COG0589@2|Bacteria,4NIWH@976|Bacteroidetes,1HXPX@117743|Flavobacteriia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp DYD2_k127_2178999_5 1296415.JACC01000050_gene1791 4.676e-190 607.0 COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia,2YI8N@290174|Aquimarina 976|Bacteroidetes P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - Sulfate_transp DYD2_k127_2178999_12 1286632.P278_03860 4.079e-79 280.0 COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,1HXGB@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA DYD2_k127_2178999_13 926549.KI421517_gene3919 2.477e-77 264.0 COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,47K3Z@768503|Cytophagia 976|Bacteroidetes T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C DYD2_k127_2178999_8 867845.KI911784_gene457 1.779e-113 378.0 COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi,377BT@32061|Chloroflexia 32061|Chloroflexia P PFAM Rieske 2Fe-2S domain protein - - 1.14.15.7 ko:K00479,ko:K00499 ko00260,map00260 - R07409 RC00087 ko00000,ko00001,ko01000 - - - Rieske,Ring_hydroxyl_A DYD2_k127_2178999_1 1150600.ADIARSV_3651 5.989e-255 796.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1INUX@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 3 family bglX - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C DYD2_k127_2184522_2 714943.Mucpa_4082 1.427e-145 469.0 COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1IPKV@117747|Sphingobacteriia 976|Bacteroidetes I PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD2_k127_2184522_1 471854.Dfer_1982 3.27e-159 511.0 COG0477@1|root,COG2814@2|Bacteria,4NG6X@976|Bacteroidetes,47KCB@768503|Cytophagia 976|Bacteroidetes EGP TIGRFAM Drug resistance transporter Bcr CflA subfamily bcr - - ko:K03446,ko:K07552 - M00701 - - ko00000,ko00002,ko02000 2.A.1.2,2.A.1.3 - - MFS_1 DYD2_k127_2184522_0 761193.Runsl_2498 8.783e-197 637.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47TJP@768503|Cytophagia 976|Bacteroidetes H Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 DYD2_k127_2184522_3 1237149.C900_00378 1.932e-09 63.0 2CB8F@1|root,34CDS@2|Bacteria,4P8GI@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2241185_0 1237149.C900_03613 2.208e-258 835.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia 976|Bacteroidetes M amine dehydrogenase activity - - - - - - - - - - - - CHU_C,VCBS DYD2_k127_2241185_1 1237149.C900_03614 2.679e-100 335.0 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia 976|Bacteroidetes M TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF DYD2_k127_2241185_2 1173022.Cri9333_0140 1.869e-12 69.0 COG0405@1|root,COG0405@2|Bacteria,1G14N@1117|Cyanobacteria,1H83V@1150|Oscillatoriales 1117|Cyanobacteria E PFAM Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD2_k127_2260303_4 399739.Pmen_0361 0.0006429 45.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,MASE1,PAS_4,PAS_9 DYD2_k127_2260303_1 1279009.ADICEAN_01001 4.992e-84 286.0 COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia 976|Bacteroidetes E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase DYD2_k127_2260303_0 1237149.C900_04442 0.0 1731.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,47JTE@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD2_k127_2260303_2 1237149.C900_04443 4.353e-11 69.0 2EJD3@1|root,33D44@2|Bacteria,4NP3M@976|Bacteroidetes,47PW7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - SPOR DYD2_k127_2267631_4 1239962.C943_03195 3.651e-09 59.0 COG5395@1|root,COG5395@2|Bacteria,4NMS3@976|Bacteroidetes 976|Bacteroidetes S membrane protein (DUF2306) - - - - - - - - - - - - DUF2306 DYD2_k127_2267631_5 1237149.C900_04948 7.395e-06 57.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - CHU_C,PKD,Peptidase_M43,fn3 DYD2_k127_2267631_0 1121904.ARBP01000006_gene4017 0.0 1534.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47NYH@768503|Cytophagia 976|Bacteroidetes H TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec DYD2_k127_2267631_1 1121904.ARBP01000006_gene4018 8.376e-172 552.0 COG0388@1|root,COG0388@2|Bacteria,4NFF2@976|Bacteroidetes,47NPY@768503|Cytophagia 976|Bacteroidetes S Pfam:SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB DYD2_k127_2267631_2 1121904.ARBP01000006_gene4019 4.788e-107 354.0 28KH3@1|root,2ZA2M@2|Bacteria,4NKS0@976|Bacteroidetes,47PKU@768503|Cytophagia 976|Bacteroidetes S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx1 DYD2_k127_2318681_0 1237149.C900_03614 1.735e-98 331.0 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia 976|Bacteroidetes M TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF DYD2_k127_2318681_1 1237149.C900_03613 3.213e-89 305.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia 976|Bacteroidetes M amine dehydrogenase activity - - - - - - - - - - - - CHU_C,VCBS DYD2_k127_2324270_6 1131812.JQMS01000001_gene2374 2.28e-63 223.0 COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1HWJW@117743|Flavobacteriia,2NUF3@237|Flavobacterium 976|Bacteroidetes Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD2_k127_2324270_2 1123248.KB893328_gene924 4.001e-114 390.0 COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,1IV5H@117747|Sphingobacteriia 976|Bacteroidetes M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - DYD2_k127_2324270_10 1123057.P872_09800 4.593e-15 76.0 2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,47SRN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - TspO_MBR DYD2_k127_2324270_8 1506583.JQJY01000008_gene3794 5.736e-19 89.0 2EIKE@1|root,33CBQ@2|Bacteria,4NXKH@976|Bacteroidetes,1I6R2@117743|Flavobacteriia,2NXQD@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2324270_9 755732.Fluta_3075 8.511e-18 89.0 2DRAU@1|root,33B03@2|Bacteria,4NXX1@976|Bacteroidetes,1IBMT@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2324270_5 938709.AUSH02000031_gene1299 1.776e-69 241.0 2DSRE@1|root,33H63@2|Bacteria 2|Bacteria S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 DYD2_k127_2324270_12 269798.CHU_3552 3.534e-10 64.0 COG4980@1|root,COG4980@2|Bacteria 2|Bacteria D gas vesicle protein XK27_07760 - - - - - - - - - - - YtxH DYD2_k127_2324270_7 1121373.KB903621_gene1839 3.652e-19 91.0 2EC34@1|root,33623@2|Bacteria,4NVW7@976|Bacteroidetes,47WFD@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Phage_holin_3_6 DYD2_k127_2324270_13 760192.Halhy_5660 2.83e-05 51.0 2EBJZ@1|root,335KD@2|Bacteria,4NWP2@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2324270_3 269798.CHU_2927 2.765e-93 317.0 COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47KDN@768503|Cytophagia 976|Bacteroidetes S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD2_k127_2324270_0 1123248.KB893320_gene3880 6.632e-171 552.0 COG0025@1|root,COG0025@2|Bacteria,4NF54@976|Bacteroidetes 976|Bacteroidetes P Sodium proton antiporter - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger DYD2_k127_2324270_1 318161.Sden_1914 4.477e-119 403.0 COG2374@1|root,COG3420@1|root,COG2374@2|Bacteria,COG3420@2|Bacteria,1QY9B@1224|Proteobacteria,1RWTJ@1236|Gammaproteobacteria,2QDA2@267890|Shewanellaceae 1236|Gammaproteobacteria P Protein of unknown function (DUF3494) - - - - - - - - - - - - Big_5,DUF3494 DYD2_k127_2324270_4 1123057.P872_04435 1.723e-76 269.0 COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria 2|Bacteria DZ guanyl-nucleotide exchange factor activity - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_1,Big_3_2,Big_5,Cadherin-like,DUF3494,TIG DYD2_k127_2327679_12 1189612.A33Q_2415 1.433e-36 141.0 COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,47R3Q@768503|Cytophagia 976|Bacteroidetes O TIGRFAM bacillithiol system protein YtxJ ytxJ - - - - - - - - - - - DUF2847 DYD2_k127_2327679_7 1237149.C900_01773 2.909e-85 289.0 28MPU@1|root,2ZAYW@2|Bacteria,4NRQD@976|Bacteroidetes,47NJK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2327679_6 1237149.C900_04701 4.217e-93 313.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD2_k127_2327679_4 1237149.C900_04691 1.271e-152 491.0 COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,47JQS@768503|Cytophagia 976|Bacteroidetes P TIGRFAM chromate transporter, chromate ion transporter (CHR) family - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD2_k127_2327679_3 1237149.C900_04690 3.327e-162 515.0 COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,47JDX@768503|Cytophagia 976|Bacteroidetes C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N DYD2_k127_2327679_14 313598.MED152_07730 9.404e-24 106.0 2DMNT@1|root,32SQG@2|Bacteria,4NSWK@976|Bacteroidetes,1I520@117743|Flavobacteriia,3VWQN@52959|Polaribacter 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2327679_5 1237149.C900_02785 4.323e-135 442.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,47KBG@768503|Cytophagia 976|Bacteroidetes H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 DYD2_k127_2327679_10 1237149.C900_02786 5.408e-69 244.0 COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,47PXV@768503|Cytophagia 976|Bacteroidetes J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS DYD2_k127_2327679_9 929556.Solca_3856 1.042e-73 253.0 COG1028@1|root,COG1028@2|Bacteria,4NGAH@976|Bacteroidetes,1ISUI@117747|Sphingobacteriia 976|Bacteroidetes IQ PFAM Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short,adh_short_C2 DYD2_k127_2327679_0 1121373.KB903662_gene75 9.369e-198 623.0 COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family rocD - 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_2327679_8 593750.Metfor_1904 6.565e-75 267.0 COG1196@1|root,arCOG00371@2157|Archaea 2157|Archaea D Required for chromosome condensation and partitioning - - - - - - - - - - - - AAA_11,AAA_12 DYD2_k127_2327679_11 1237149.C900_01745 9.73e-60 208.0 COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes,47Q9W@768503|Cytophagia 976|Bacteroidetes O Chaperonin 10 Kd subunit - - - - - - - - - - - - Cpn10 DYD2_k127_2327679_15 153721.MYP_2511 1.854e-13 73.0 2ECIG@1|root,33HGA@2|Bacteria,4NXUX@976|Bacteroidetes,47T4J@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2327679_2 643867.Ftrac_0960 1.03e-180 578.0 COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,47MY8@768503|Cytophagia 976|Bacteroidetes E Belongs to the peptidase M24B family - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 DYD2_k127_2327679_1 1121374.KB891575_gene1187 1.651e-190 610.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RPCH@1236|Gammaproteobacteria 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl DYD2_k127_2334383_9 163908.KB235896_gene649 1.23e-15 90.0 COG1404@1|root,COG1404@2|Bacteria,1G04D@1117|Cyanobacteria,1HK7S@1161|Nostocales 1117|Cyanobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - PPC,Peptidase_S8 DYD2_k127_2334383_3 1123057.P872_07685 4.542e-93 316.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47TNT@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2334383_5 1120965.AUBV01000015_gene1058 1.363e-61 227.0 COG5337@1|root,COG5337@2|Bacteria,4P3EE@976|Bacteroidetes 976|Bacteroidetes M CotH kinase protein - - - ko:K06330 - - - - ko00000 - - - CotH DYD2_k127_2334383_8 761193.Runsl_2102 4.779e-34 138.0 arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,47PEP@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4956) - - - - - - - - - - - - DUF4956 DYD2_k127_2334383_2 1123057.P872_07680 4.474e-161 520.0 COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia 976|Bacteroidetes NU PFAM metallophosphoesterase - - - - - - - - - - - - Metallophos DYD2_k127_2334383_7 1379698.RBG1_1C00001G0518 6.987e-53 213.0 COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase,TPR_2,TPR_8 DYD2_k127_2334383_0 1313421.JHBV01000014_gene4038 1.42e-308 961.0 COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase S9, prolyl oligopeptidase, catalytic domain ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N DYD2_k127_2334383_1 925409.KI911562_gene2742 4.921e-171 541.0 COG2114@1|root,COG2204@1|root,COG2114@2|Bacteria,COG2204@2|Bacteria,4NF1F@976|Bacteroidetes,1IPZU@117747|Sphingobacteriia 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,Response_reg DYD2_k127_2334383_6 1392498.JQLH01000001_gene2544 3.931e-53 189.0 COG0745@1|root,COG0745@2|Bacteria,4NQ69@976|Bacteroidetes,1I32T@117743|Flavobacteriia,2PIMN@252356|Maribacter 976|Bacteroidetes KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD2_k127_2334383_4 1223410.KN050846_gene2836 2.808e-67 231.0 COG4191@1|root,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,SnoaL_3 DYD2_k127_2366398_3 1227739.Hsw_4060 1.355e-108 360.0 COG0659@1|root,COG0659@2|Bacteria 2|Bacteria P secondary active sulfate transmembrane transporter activity - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - MFS_MOT1 DYD2_k127_2366398_5 760192.Halhy_5119 3.82e-43 163.0 COG3182@1|root,COG3182@2|Bacteria,4NIXJ@976|Bacteroidetes,1IXT7@117747|Sphingobacteriia 976|Bacteroidetes S PepSY-associated TM region - - - ko:K09939 - - - - ko00000 - - - PepSY_TM DYD2_k127_2366398_2 762968.HMPREF9441_02841 4.939e-220 704.0 COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes 976|Bacteroidetes P Outer membrane receptor - - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,TonB_dep_Rec DYD2_k127_2366398_0 1122176.KB903536_gene1741 0.0 1561.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,1IVI6@117747|Sphingobacteriia 976|Bacteroidetes QU Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,PD40 DYD2_k127_2366398_4 509635.N824_26345 9.217e-44 166.0 COG1595@1|root,COG1595@2|Bacteria,4NQR9@976|Bacteroidetes,1IST5@117747|Sphingobacteriia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_2366398_6 1122621.ATZA01000046_gene3482 1.524e-16 85.0 2CBBA@1|root,3313Q@2|Bacteria,4NWRR@976|Bacteroidetes,1IU7S@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2366398_1 1237149.C900_01494 2.83e-236 747.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2367986_9 643867.Ftrac_2586 5.219e-142 454.0 COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,47KBV@768503|Cytophagia 976|Bacteroidetes L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB DYD2_k127_2367986_14 1124780.ANNU01000006_gene2811 4.733e-79 271.0 COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,47JZN@768503|Cytophagia 976|Bacteroidetes E PFAM Shikimate dehydrogenase substrate binding domain aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N DYD2_k127_2367986_10 1279009.ADICEAN_02040 1.15e-110 365.0 COG2035@1|root,COG2035@2|Bacteria,4NFKI@976|Bacteroidetes,47MKT@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 DYD2_k127_2367986_8 1237149.C900_02373 1.612e-142 455.0 COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,47MRM@768503|Cytophagia 976|Bacteroidetes S PFAM (2R)-phospho-3-sulfolactate synthase ComA - - 4.4.1.19 ko:K08097 ko00680,ko01120,map00680,map01120 M00358 R07476 RC01799 ko00000,ko00001,ko00002,ko01000 - - - ComA DYD2_k127_2367986_2 1237149.C900_02372 8.716e-192 606.0 COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,47M8A@768503|Cytophagia 976|Bacteroidetes NU PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 DYD2_k127_2367986_12 313606.M23134_00029 6.123e-86 295.0 COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,47M93@768503|Cytophagia 976|Bacteroidetes M PFAM NAD dependent epimerase dehydratase family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase,NAD_binding_4 DYD2_k127_2367986_15 1237149.C900_02370 1.303e-71 249.0 COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,47PBY@768503|Cytophagia 976|Bacteroidetes GM capsular polysaccharide biosynthesis protein - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - DYD2_k127_2367986_1 1237149.C900_02369 6.842e-226 724.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia 976|Bacteroidetes DM TIGRFAM capsular exopolysaccharide family - - - - - - - - - - - - AAA_31,CbiA,GNVR,Wzz DYD2_k127_2367986_19 1237149.C900_02368 1.656e-59 216.0 COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,47Q04@768503|Cytophagia 976|Bacteroidetes M Polysaccharide biosynthesis/export protein - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export DYD2_k127_2367986_18 1237149.C900_02367 5.809e-60 213.0 COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,47PQR@768503|Cytophagia 976|Bacteroidetes M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom DYD2_k127_2367986_6 1237149.C900_02366 6.742e-145 467.0 COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,47KFQ@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase 4-like - - - ko:K13004 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 DYD2_k127_2367986_7 1237149.C900_02365 1.812e-144 467.0 COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,47JGI@768503|Cytophagia 976|Bacteroidetes S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 DYD2_k127_2367986_24 388413.ALPR1_03850 5.345e-27 111.0 COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes 976|Bacteroidetes L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD2_k127_2367986_11 866536.Belba_0530 8.958e-91 309.0 COG0457@1|root,COG0457@2|Bacteria,4NJ7M@976|Bacteroidetes,47N78@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_6,TPR_8 DYD2_k127_2367986_3 925409.KI911562_gene612 6.543e-185 589.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 DYD2_k127_2367986_25 1121481.AUAS01000006_gene670 5.395e-18 88.0 COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,47KY5@768503|Cytophagia 976|Bacteroidetes L Superfamily I DNA and RNA - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 DYD2_k127_2367986_0 1237149.C900_05507 0.0 1334.0 COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,47KY5@768503|Cytophagia 976|Bacteroidetes L Superfamily I DNA and RNA - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 DYD2_k127_2367986_17 926549.KI421517_gene155 1.241e-60 220.0 COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,47KXV@768503|Cytophagia 976|Bacteroidetes L Helix-hairpin-helix motif comEA - - - - - - - - - - - HHH_3 DYD2_k127_2367986_20 1124780.ANNU01000002_gene1605 1.234e-57 207.0 COG3931@1|root,COG3931@2|Bacteria,4NMA3@976|Bacteroidetes,47UX9@768503|Cytophagia 976|Bacteroidetes E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase DYD2_k127_2367986_5 1237149.C900_03855 4.479e-148 479.0 COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes 976|Bacteroidetes S Glutamate-cysteine ligase family 2(GCS2) - - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 DYD2_k127_2367986_4 1237149.C900_03854 1.672e-171 550.0 COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,47P1C@768503|Cytophagia 976|Bacteroidetes HJ RimK-like ATPgrasp N-terminal domain - - - - - - - - - - - - Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK DYD2_k127_2367986_13 1237149.C900_03853 8.869e-80 273.0 COG3271@1|root,COG3271@2|Bacteria,4NN8E@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - Peptidase_C39_2 DYD2_k127_2367986_16 471854.Dfer_4627 4.749e-69 238.0 COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,47P9R@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI DYD2_k127_2367986_21 1189612.A33Q_3600 3.713e-55 199.0 COG0664@1|root,COG0664@2|Bacteria,4NJRX@976|Bacteroidetes,47QTJ@768503|Cytophagia 976|Bacteroidetes T Cyclic nucleotide-binding domain - - - - - - - - - - - - cNMP_binding DYD2_k127_2367986_23 903814.ELI_3666 1.319e-33 135.0 COG3760@1|root,COG3760@2|Bacteria,1V1JF@1239|Firmicutes,24FVD@186801|Clostridia,25W3H@186806|Eubacteriaceae 186801|Clostridia S Aminoacyl-tRNA editing domain proX - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit DYD2_k127_2367986_22 1121481.AUAS01000009_gene196 9.395e-46 167.0 COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes,47PN4@768503|Cytophagia 976|Bacteroidetes P Rhodanese Homology Domain sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD2_k127_2372350_3 1120966.AUBU01000003_gene1407 1.279e-72 247.0 COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,47KCH@768503|Cytophagia 976|Bacteroidetes E PFAM Glyoxalase bleomycin resistance protein dioxygenase hppD - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 DYD2_k127_2372350_5 1237149.C900_05647 6.27e-40 153.0 2DN0J@1|root,32UI3@2|Bacteria,4NT4U@976|Bacteroidetes,47R55@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2372350_0 1124780.ANNU01000032_gene1270 6.699e-165 523.0 COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b DYD2_k127_2372350_4 1380384.JADN01000004_gene2134 8.491e-63 224.0 2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4382) - - - - - - - - - - - - CarboxypepD_reg,DUF4382 DYD2_k127_2372350_1 1453500.AT05_06665 4.804e-141 456.0 COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia 976|Bacteroidetes M Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.23 ko:K13019 ko00520,map00520 - R09600 RC00290 ko00000,ko00001,ko01000,ko01005 - - - Epimerase_2 DYD2_k127_2372350_2 1237149.C900_05076 1.53e-114 370.0 COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,47KQK@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_2391318_10 643867.Ftrac_0021 5.526e-179 566.0 COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia 976|Bacteroidetes I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE DYD2_k127_2391318_25 643867.Ftrac_3478 2.214e-83 283.0 COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes,47M5I@768503|Cytophagia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD2_k127_2391318_21 1237149.C900_03289 1.603e-104 344.0 COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,47N59@768503|Cytophagia 976|Bacteroidetes Q ABC-type transport system involved in resistance to organic solvents permease component mlaE - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD2_k127_2391318_20 1237149.C900_03288 7.097e-116 380.0 COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,47K20@768503|Cytophagia 976|Bacteroidetes Q ABC-type transport system involved in resistance to organic solvents, ATPase component metN - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD2_k127_2391318_5 1237149.C900_03280 8.477e-256 831.0 COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,47JEP@768503|Cytophagia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zraS_1 - - - - - - - - - - - HATPase_c,HisKA DYD2_k127_2391318_38 1166018.FAES_1084 3.963e-30 123.0 COG5349@1|root,COG5349@2|Bacteria,4NQ87@976|Bacteroidetes,47RHB@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF983) - - - - - - - - - - - - DUF983 DYD2_k127_2391318_39 641524.ADICYQ_5759 2.147e-17 84.0 2BT8H@1|root,32NDW@2|Bacteria,4P9FZ@976|Bacteroidetes,47R82@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2391318_30 1237149.C900_03277 4.959e-69 237.0 COG2322@1|root,COG2322@2|Bacteria,4NM5N@976|Bacteroidetes,47QB2@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF420) yozB - - ko:K08976 - - - - ko00000 - - - DUF420 DYD2_k127_2391318_41 1279009.ADICEAN_01821 1.529e-09 66.0 COG1999@1|root,COG1999@2|Bacteria,4NMTA@976|Bacteroidetes,47Q9J@768503|Cytophagia 976|Bacteroidetes S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD2_k127_2391318_37 1237149.C900_03275 1.432e-34 135.0 COG5605@1|root,COG5605@2|Bacteria,4NTVI@976|Bacteroidetes,47R14@768503|Cytophagia 976|Bacteroidetes S Prokaryotic Cytochrome C oxidase subunit IV - - - - - - - - - - - - COX4_pro DYD2_k127_2391318_18 1237149.C900_03274 5.426e-123 398.0 COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,47JVP@768503|Cytophagia 976|Bacteroidetes C cytochrome c oxidase subunit III coxP - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 DYD2_k127_2391318_28 880070.Cycma_2291 3.416e-75 257.0 COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,47NS2@768503|Cytophagia 976|Bacteroidetes C PFAM cytochrome c oxidase subunit III ctaE - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 DYD2_k127_2391318_17 1237149.C900_03272 2.742e-128 415.0 COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,47MB0@768503|Cytophagia 976|Bacteroidetes O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA DYD2_k127_2391318_23 1237149.C900_03271 8.229e-93 316.0 COG1612@1|root,COG1612@2|Bacteria,4NEBR@976|Bacteroidetes,47JI1@768503|Cytophagia 976|Bacteroidetes O Cytochrome oxidase assembly protein ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA DYD2_k127_2391318_2 1237149.C900_03270 0.0 1111.0 COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,47JBQ@768503|Cytophagia 976|Bacteroidetes C Belongs to the heme-copper respiratory oxidase family coxN - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 DYD2_k127_2391318_15 1237149.C900_03269 4.081e-135 439.0 COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,47JF8@768503|Cytophagia 976|Bacteroidetes C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM DYD2_k127_2391318_8 1237149.C900_03268 1.838e-203 641.0 COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,47JUF@768503|Cytophagia 976|Bacteroidetes P Quinol cytochrome c oxidoreductase actF - - - - - - - - - - - - DYD2_k127_2391318_29 1120965.AUBV01000009_gene2941 5.104e-72 249.0 COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,47PEX@768503|Cytophagia 976|Bacteroidetes C PFAM Cytochrome C actE - - - - - - - - - - - Cytochrome_CBB3 DYD2_k127_2391318_26 1237149.C900_03266 1.854e-81 273.0 COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,47K4U@768503|Cytophagia 976|Bacteroidetes C Quinol cytochrome c oxidoreductase membrane protein actD - - - - - - - - - - - DUF3341 DYD2_k127_2391318_6 1237149.C900_03265 1.347e-251 781.0 COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia 976|Bacteroidetes C PFAM Polysulphide reductase, NrfD nrfD - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD DYD2_k127_2391318_0 926556.Echvi_2097 0.0 1279.0 COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain nrfC - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molydop_binding DYD2_k127_2391318_12 1237149.C900_03263 3.692e-150 485.0 COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,47J8Z@768503|Cytophagia 976|Bacteroidetes C PFAM Class III cytochrome C family actA - - - - - - - - - - - Cytochrom_C,Cytochrom_CIII,Cytochrome_C7 DYD2_k127_2391318_40 518766.Rmar_0335 2.004e-15 83.0 2EH9H@1|root,30IPX@2|Bacteria,4PF9X@976|Bacteroidetes,1FKCD@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2391318_9 1189619.pgond44_14158 1.214e-182 581.0 COG0160@1|root,COG0160@2|Bacteria,4NFWF@976|Bacteroidetes,1HY4F@117743|Flavobacteriia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_2391318_16 1121904.ARBP01000053_gene478 2.1e-134 434.0 COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,47JFJ@768503|Cytophagia 976|Bacteroidetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - CN_hydrolase DYD2_k127_2391318_35 926562.Oweho_2529 2.008e-46 170.0 COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,1IGP2@117743|Flavobacteriia,2PBXR@246874|Cryomorphaceae 976|Bacteroidetes S Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase DYD2_k127_2391318_1 746697.Aeqsu_2889 0.0 1179.0 COG1982@1|root,COG1982@2|Bacteria,4NHSM@976|Bacteroidetes,1I0X3@117743|Flavobacteriia 976|Bacteroidetes E PFAM Orn Lys Arg decarboxylase, C-terminal domain - - 4.1.1.19 ko:K01584 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C DYD2_k127_2391318_11 1121904.ARBP01000053_gene480 4.344e-154 500.0 COG0833@1|root,COG0833@2|Bacteria,4PPC8@976|Bacteroidetes 976|Bacteroidetes E Amino acid permease - - - ko:K11733 - - - - ko00000,ko02000 2.A.3.1.2 - - AA_permease DYD2_k127_2391318_7 313606.M23134_08397 5.602e-242 757.0 COG1038@1|root,COG1038@2|Bacteria,4NGX2@976|Bacteroidetes,47TRK@768503|Cytophagia 976|Bacteroidetes C ATP-grasp domain - - - - - - - - - - - - - DYD2_k127_2391318_19 1121904.ARBP01000053_gene482 2.584e-117 385.0 COG4927@1|root,COG4927@2|Bacteria,4NGS4@976|Bacteroidetes,47TR3@768503|Cytophagia 976|Bacteroidetes S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT DYD2_k127_2391318_36 391603.FBALC1_09457 2.723e-41 160.0 2CDZ7@1|root,2Z8VK@2|Bacteria,4NIYY@976|Bacteroidetes,1I1XD@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DoxX DYD2_k127_2391318_14 1120965.AUBV01000004_gene1033 2.452e-138 448.0 COG2010@1|root,COG2010@2|Bacteria,4NMGT@976|Bacteroidetes 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C DYD2_k127_2391318_4 1163409.UUA_08346 4.683e-260 826.0 COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,1RXYW@1236|Gammaproteobacteria,1XD03@135614|Xanthomonadales 135614|Xanthomonadales U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 DYD2_k127_2391318_34 1267211.KI669560_gene1630 3.78e-48 178.0 COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1IYQI@117747|Sphingobacteriia 976|Bacteroidetes M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin DYD2_k127_2391318_24 1048983.EL17_22570 1.897e-90 304.0 COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,47KSX@768503|Cytophagia 976|Bacteroidetes S ABC-2 family transporter protein - - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2,ABC2_membrane_5 DYD2_k127_2391318_27 1341155.FSS13T_01890 1.026e-77 266.0 COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1HYYD@117743|Flavobacteriia,2NU88@237|Flavobacterium 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - ko:K19340 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC_tran DYD2_k127_2391318_13 1048983.EL17_22580 8.34e-150 484.0 COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,47KEF@768503|Cytophagia 976|Bacteroidetes P Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD DYD2_k127_2391318_22 761193.Runsl_0112 4.235e-101 339.0 COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,47NSZ@768503|Cytophagia 976|Bacteroidetes C lipoprotein involved in nitrous oxide reduction - - - ko:K19342 - - - - ko00000 - - - NosL DYD2_k127_2391318_3 761193.Runsl_0111 0.0 1060.0 COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,47KTB@768503|Cytophagia 976|Bacteroidetes C Nitrous oxide reductase nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - - DYD2_k127_2391318_33 760192.Halhy_5490 2.423e-50 183.0 COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1ISPY@117747|Sphingobacteriia 976|Bacteroidetes C PFAM cytochrome c - - - - - - - - - - - - Cytochrom_C DYD2_k127_2391318_32 1237149.C900_01994 7.115e-61 218.0 COG0664@1|root,COG0664@2|Bacteria,4NM5E@976|Bacteroidetes,47R9U@768503|Cytophagia 976|Bacteroidetes K Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - HTH_Crp_2,cNMP_binding DYD2_k127_2397463_7 643867.Ftrac_0494 2.337e-106 352.0 COG4249@1|root,COG4249@2|Bacteria,4NSC3@976|Bacteroidetes,47S66@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14,TPR_2 DYD2_k127_2397463_6 761193.Runsl_1977 8.726e-118 393.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,PAS_8 DYD2_k127_2397463_1 1237149.C900_04093 2.977e-239 746.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD2_k127_2397463_4 1237149.C900_04092 4.619e-187 593.0 COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,47N10@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD2_k127_2397463_5 1237149.C900_04091 6.51e-136 434.0 COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47KMI@768503|Cytophagia 976|Bacteroidetes V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_2397463_2 1237149.C900_05293 2.411e-231 740.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2397463_0 1237149.C900_05294 2.409e-269 851.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2397463_3 1237149.C900_05294 7.171e-199 636.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2397463_8 1237149.C900_05294 9.981e-67 232.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2397463_9 760192.Halhy_4111 4.475e-26 110.0 COG4447@1|root,COG4447@2|Bacteria,4NK5F@976|Bacteroidetes,1IWI3@117747|Sphingobacteriia 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - - DYD2_k127_243319_4 1237149.C900_01608 1.867e-95 318.0 COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MCZ@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD2_k127_243319_0 1237149.C900_01606 2.89e-218 694.0 COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,47M73@768503|Cytophagia 976|Bacteroidetes L ATP-dependent DNA helicase RecQ recQ2 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind DYD2_k127_243319_2 714943.Mucpa_1535 4.42e-180 571.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,1IPGS@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK DYD2_k127_243319_1 1123057.P872_08525 1.911e-181 572.0 COG0205@1|root,COG0205@2|Bacteria,4NGN7@976|Bacteroidetes,47TRF@768503|Cytophagia 976|Bacteroidetes F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK DYD2_k127_243319_3 1120965.AUBV01000005_gene1608 1.417e-118 389.0 COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia 976|Bacteroidetes J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine sua5 - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC DYD2_k127_243319_5 761193.Runsl_4400 9.277e-45 166.0 COG1051@1|root,COG1051@2|Bacteria,4NNJ5@976|Bacteroidetes,47PUZ@768503|Cytophagia 976|Bacteroidetes F pfam nudix - - - - - - - - - - - - NUDIX DYD2_k127_2542082_7 1279009.ADICEAN_04204 6.848e-61 213.0 COG0566@1|root,COG0566@2|Bacteria,4NEFJ@976|Bacteroidetes,47UQQ@768503|Cytophagia 976|Bacteroidetes J SpoU rRNA Methylase family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind DYD2_k127_2542082_2 1123035.ARLA01000021_gene953 1.184e-111 369.0 COG0438@1|root,COG0438@2|Bacteria,4NIWP@976|Bacteroidetes,1HZJU@117743|Flavobacteriia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 DYD2_k127_2542082_1 1237149.C900_01588 1.974e-113 382.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - 3.4.11.2,3.4.24.3 ko:K01256,ko:K01387 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002,ko02042 - - - HEAT_2,HEAT_PBS,Peptidase_M1,Peptidase_M9,Peptidase_M9_N DYD2_k127_2542082_4 1237149.C900_01589 1.151e-90 310.0 COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia 976|Bacteroidetes T PFAM histidine kinase internal region - - - - - - - - - - - - His_kinase DYD2_k127_2542082_6 1237149.C900_01590 5.298e-78 273.0 COG2972@1|root,COG2972@2|Bacteria,4NPKE@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase DYD2_k127_2542082_3 1237149.C900_01591 1.143e-97 325.0 COG3279@1|root,COG3279@2|Bacteria,4NJW4@976|Bacteroidetes 976|Bacteroidetes T LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg DYD2_k127_2542082_0 1237149.C900_02054 0.0 1129.0 COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47YDB@768503|Cytophagia 976|Bacteroidetes O Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 DYD2_k127_2542082_5 1189612.A33Q_3933 2.374e-78 267.0 COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,47UM2@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD2_k127_2542082_8 1380384.JADN01000003_gene343 2.261e-27 117.0 COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1I3IT@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3,Reg_prop,Y_Y_Y DYD2_k127_2560182_1 1123277.KB893172_gene540 7.386e-103 347.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_2560182_2 1189612.A33Q_1144 3.402e-75 254.0 COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,47P72@768503|Cytophagia 976|Bacteroidetes O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase DYD2_k127_2560182_0 1185876.BN8_06470 9.875e-113 369.0 COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47JE7@768503|Cytophagia 976|Bacteroidetes S Penicillin amidase - - - - - - - - - - - - Penicil_amidase DYD2_k127_2598690_14 1237149.C900_03646 8.936e-52 185.0 COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,47QDT@768503|Cytophagia 976|Bacteroidetes O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD2_k127_2598690_12 929703.KE386491_gene3958 1.711e-63 221.0 COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,47QHT@768503|Cytophagia 976|Bacteroidetes S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC DYD2_k127_2598690_21 1121015.N789_09315 6.982e-29 126.0 COG4319@1|root,COG4319@2|Bacteria,1PZUH@1224|Proteobacteria,1SUHF@1236|Gammaproteobacteria,1XBQN@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 DYD2_k127_2598690_10 313603.FB2170_05365 2.57e-80 272.0 COG0652@1|root,COG0652@2|Bacteria,4NMG5@976|Bacteroidetes,1IIU3@117743|Flavobacteriia,2PI54@252356|Maribacter 976|Bacteroidetes O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase DYD2_k127_2598690_2 865937.Gilli_0356 3.905e-244 761.0 COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1HXGY@117743|Flavobacteriia,2P60C@244698|Gillisia 976|Bacteroidetes E Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 DYD2_k127_2598690_8 700598.Niako_0187 3.591e-102 341.0 COG2367@1|root,COG2367@2|Bacteria,4PMKC@976|Bacteroidetes,1J006@117747|Sphingobacteriia 976|Bacteroidetes V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 DYD2_k127_2598690_4 714943.Mucpa_4117 1e-172 552.0 COG0531@1|root,COG0531@2|Bacteria,4NIZB@976|Bacteroidetes,1IP7H@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Amino acid - - - ko:K03294,ko:K03758 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 DYD2_k127_2598690_7 313603.FB2170_03985 6.533e-124 402.0 COG1834@1|root,COG1834@2|Bacteria,4NGKJ@976|Bacteroidetes,1I0NU@117743|Flavobacteriia 976|Bacteroidetes E Amidinotransferase - - - - - - - - - - - - Amidinotransf DYD2_k127_2598690_13 866536.Belba_2715 5.076e-60 208.0 COG0599@1|root,COG0599@2|Bacteria,4NNPC@976|Bacteroidetes,47QDA@768503|Cytophagia 976|Bacteroidetes S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD2_k127_2598690_5 866536.Belba_2716 2.65e-162 517.0 COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,47KUF@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3641) - - - - - - - - - - - - DUF3641,Fer4_12,Radical_SAM DYD2_k127_2598690_18 1237149.C900_04165 6.604e-35 137.0 COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,47R30@768503|Cytophagia 976|Bacteroidetes J RF-1 domain arfB - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 DYD2_k127_2598690_9 700598.Niako_2665 1.069e-101 337.0 COG1235@1|root,COG1235@2|Bacteria,4NDVI@976|Bacteroidetes,1IR6D@117747|Sphingobacteriia 976|Bacteroidetes S COGs COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I vicX - - - - - - - - - - - Lactamase_B,Lactamase_B_2 DYD2_k127_2598690_1 1047013.AQSP01000029_gene2170 8.765e-250 779.0 COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria 2|Bacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD2_k127_2598690_3 468059.AUHA01000004_gene2197 1.683e-241 754.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA DYD2_k127_2598690_25 1280688.AUJB01000008_gene973 2.306e-12 68.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia 186801|Clostridia KT PFAM PspC domain - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC DYD2_k127_2598690_6 1279009.ADICEAN_00381 1.667e-139 449.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD2_k127_2598690_26 468059.AUHA01000002_gene85 8.828e-09 63.0 2EC83@1|root,3366K@2|Bacteria,4NWPR@976|Bacteroidetes,1ITW7@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2598690_24 926562.Oweho_0658 2.491e-14 80.0 COG4704@1|root,COG4704@2|Bacteria,4P9RE@976|Bacteroidetes,1ICNA@117743|Flavobacteriia,2PB7B@246874|Cryomorphaceae 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2141) - - - - - - - - - - - - DUF2141 DYD2_k127_2598690_11 292415.Tbd_2707 6.727e-78 266.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,1KT5D@119069|Hydrogenophilales 119069|Hydrogenophilales S Haemolysin-III related - - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII DYD2_k127_2598690_19 1189620.AJXL01000106_gene3273 1.24e-33 136.0 COG3631@1|root,COG3631@2|Bacteria,4P470@976|Bacteroidetes 976|Bacteroidetes S Ketosteroid isomerase-related protein - - - - - - - - - - - - - DYD2_k127_2598690_17 1209072.ALBT01000029_gene2244 6.446e-43 160.0 2C85M@1|root,31482@2|Bacteria,1N2W2@1224|Proteobacteria,1S666@1236|Gammaproteobacteria,1FHA7@10|Cellvibrio 1236|Gammaproteobacteria S Stress responsive A/B Barrel Domain - - - - - - - - - - - - Dabb,TAT_signal DYD2_k127_2598690_15 485918.Cpin_3973 1.418e-50 183.0 COG0346@1|root,COG0346@2|Bacteria,4NSC9@976|Bacteroidetes,1ISQR@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD2_k127_2598690_20 714943.Mucpa_1891 2.935e-32 128.0 COG2350@1|root,COG2350@2|Bacteria,4NVI4@976|Bacteroidetes,1IUFS@117747|Sphingobacteriia 976|Bacteroidetes S YCII-related domain - - - - - - - - - - - - YCII DYD2_k127_2598690_0 926549.KI421517_gene8 1.042e-321 1012.0 COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,47JU2@768503|Cytophagia 976|Bacteroidetes S Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C DYD2_k127_2629089_1 1403819.BATR01000133_gene4702 3.637e-77 267.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator exsA GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051596,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1903506,GO:2000112,GO:2001141 - ko:K20968 ko02025,map02025 - - - ko00000,ko00001,ko03000 - - - HTH_18 DYD2_k127_2629089_5 164328.Phyra79286 1.066e-13 79.0 KOG4064@1|root,KOG4064@2759|Eukaryota,3QFAF@4776|Peronosporales 4776|Peronosporales E Cysteine dioxygenase type I - - 1.13.11.20 ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 - R00893 RC00404 ko00000,ko00001,ko01000 - - - CDO_I DYD2_k127_2629089_2 1286632.P278_03710 4.473e-44 163.0 COG2044@1|root,COG2044@2|Bacteria,4P2I4@976|Bacteroidetes,1I8SH@117743|Flavobacteriia 976|Bacteroidetes S DsrE/DsrF-like family - - - - - - - - - - - - DrsE DYD2_k127_2629089_3 1229204.AMYY01000001_gene2822 3.563e-21 100.0 2B5YT@1|root,31YUV@2|Bacteria,1RF42@1224|Proteobacteria,2U8FC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3088) - - - - - - - - - - - - DUF3088 DYD2_k127_2629089_4 203119.Cthe_2454 1.4e-18 101.0 COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1TSZ3@1239|Firmicutes,24AU1@186801|Clostridia,3WMWP@541000|Ruminococcaceae 186801|Clostridia G Fibronectin type III domain - - - - - - - - - - - - SLH,fn3 DYD2_k127_2629089_0 938709.AUSH02000020_gene1986 3.634e-81 296.0 COG3656@1|root,COG5295@1|root,COG3656@2|Bacteria,COG5295@2|Bacteria,4NHDQ@976|Bacteroidetes 976|Bacteroidetes UW fibronectin type III domain protein - - - ko:K21571 - - - - ko00000 - - - - DYD2_k127_2648126_6 1121897.AUGO01000010_gene2764 1.031e-97 328.0 COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes,1HYIV@117743|Flavobacteriia,2NT7P@237|Flavobacterium 976|Bacteroidetes P Rhodanese Homology Domain sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD2_k127_2648126_0 1223410.KN050846_gene379 0.0 1228.0 COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia 976|Bacteroidetes P heavy metal translocating P-type ATPase silP - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase DYD2_k127_2648126_4 700598.Niako_1201 4.092e-125 430.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_2648126_7 926556.Echvi_3204 1.678e-55 200.0 COG4319@1|root,COG4319@2|Bacteria,4PKP4@976|Bacteroidetes,47YGA@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 DYD2_k127_2648126_3 1237149.C900_02493 5.474e-135 441.0 COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2 DYD2_k127_2648126_8 1237149.C900_02494 3.412e-41 157.0 COG0526@1|root,COG0526@2|Bacteria,4NS1W@976|Bacteroidetes,47WNY@768503|Cytophagia 976|Bacteroidetes O Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin,Thioredoxin_8 DYD2_k127_2648126_9 1086011.HJ01_01366 1.012e-07 56.0 COG0845@1|root,COG0845@2|Bacteria,4NISM@976|Bacteroidetes,1IIHT@117743|Flavobacteriia,2NWK2@237|Flavobacterium 976|Bacteroidetes M Protein of unknown function (DUF3347) - - - - - - - - - - - - DUF3347 DYD2_k127_2648126_1 880070.Cycma_4598 8.094e-206 655.0 COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,47K97@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07798,ko:K15727 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 - - DUF3347,HMA,HlyD_D23 DYD2_k127_2648126_5 643867.Ftrac_2112 2.112e-108 364.0 COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,47NKF@768503|Cytophagia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP DYD2_k127_2648126_2 1250232.JQNJ01000001_gene3928 1.868e-184 581.0 COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IJ7V@117743|Flavobacteriia 976|Bacteroidetes P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07787,ko:K15726 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.2,2.A.6.1.4 - - ACR_tran DYD2_k127_2670542_2 1123248.KB893359_gene2071 1.252e-114 373.0 COG1432@1|root,COG1432@2|Bacteria,4NGF1@976|Bacteroidetes,1IRKK@117747|Sphingobacteriia 976|Bacteroidetes S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH DYD2_k127_2670542_3 414684.RC1_2143 1.112e-97 330.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VG2H@28211|Alphaproteobacteria,2JZP7@204441|Rhodospirillales 204441|Rhodospirillales P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske DYD2_k127_2670542_1 1121904.ARBP01000004_gene928 5.122e-133 436.0 COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,47NVA@768503|Cytophagia 976|Bacteroidetes P PFAM sodium hydrogen exchanger - - - - - - - - - - - - Na_H_Exchanger DYD2_k127_2670542_0 1121904.ARBP01000004_gene929 1.006e-234 733.0 COG0470@1|root,COG0531@1|root,COG0470@2|Bacteria,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,47KCI@768503|Cytophagia 976|Bacteroidetes E Amino acid permease - - - - - - - - - - - - AA_permease,SLC12 DYD2_k127_2680168_0 1237149.C900_01765 0.0 1906.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,47JB7@768503|Cytophagia 976|Bacteroidetes E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase DYD2_k127_2680168_1 1237149.C900_01764 3.577e-212 669.0 COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,47M2V@768503|Cytophagia 976|Bacteroidetes E TIGRFAM glutamate synthases, NADH NADPH, small subunit gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 DYD2_k127_2680168_3 313596.RB2501_04510 2.89e-09 70.0 2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia 976|Bacteroidetes S TIR domain - - - - - - - - - - - - TIR_2 DYD2_k127_2680168_2 221288.JH992901_gene5748 1.191e-52 201.0 COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria 1117|Cyanobacteria A WD domain, G-beta repeat - - - - - - - - - - - - WD40 DYD2_k127_2685469_1 1121094.KB894644_gene2241 7.955e-137 448.0 COG0688@1|root,COG0688@2|Bacteria,4NR69@976|Bacteroidetes,2FVV1@200643|Bacteroidia 976|Bacteroidetes I Phosphatidylserine decarboxylase - - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PSDC,PS_Dcarbxylase DYD2_k127_2685469_2 143224.JQMD01000002_gene2500 4.113e-113 376.0 COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HY9H@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - Beta-lactamase DYD2_k127_2685469_0 1237149.C900_04831 1.018e-166 530.0 COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,47NVE@768503|Cytophagia 976|Bacteroidetes I Fatty acid desaturase alkB - 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase DYD2_k127_2685469_3 1492737.FEM08_32050 6.729e-43 160.0 COG3383@1|root,COG3383@2|Bacteria 2|Bacteria C formate dehydrogenase (NAD+) activity fdsA - 1.17.1.10,1.17.1.9 ko:K00123,ko:K05299 ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200 M00377 R00134,R00519 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD2_k127_2702581_14 1124780.ANNU01000028_gene992 2.029e-57 208.0 COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,47MQE@768503|Cytophagia 976|Bacteroidetes S Polysaccharide biosynthesis protein cap - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C DYD2_k127_2702581_7 1237149.C900_04719 2.54e-136 440.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,47JUZ@768503|Cytophagia 976|Bacteroidetes M PFAM NAD dependent epimerase dehydratase family ltd - - - - - - - - - - - Epimerase DYD2_k127_2702581_1 1237149.C900_04723 1.32e-221 691.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,47MGP@768503|Cytophagia 976|Bacteroidetes H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_2702581_11 1237149.C900_04724 2.768e-104 346.0 COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,47JT6@768503|Cytophagia 976|Bacteroidetes S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - - - - - - - - - - - DisA_N DYD2_k127_2702581_12 938709.AUSH02000069_gene1541 1.174e-103 345.0 COG0294@1|root,COG0294@2|Bacteria,4NEYJ@976|Bacteroidetes 976|Bacteroidetes H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind DYD2_k127_2702581_13 1237149.C900_04726 1.614e-85 287.0 28HFG@1|root,2Z7RJ@2|Bacteria,4NFNY@976|Bacteroidetes,47PDT@768503|Cytophagia 976|Bacteroidetes S Domain of Unknown Function (DUF1599) - - - - - - - - - - - - DUF1599 DYD2_k127_2702581_5 1237149.C900_04727 1.285e-149 481.0 COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,47JTZ@768503|Cytophagia 976|Bacteroidetes S DoxX family doxX - - - - - - - - - - - DoxX DYD2_k127_2702581_17 866536.Belba_0157 6.15e-36 142.0 COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,47QWF@768503|Cytophagia 976|Bacteroidetes F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI DYD2_k127_2702581_10 1189612.A33Q_0655 2.577e-104 356.0 COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,47K28@768503|Cytophagia 976|Bacteroidetes I PFAM Outer membrane protein transport protein (OMPP1 FadL TodX) - - - - - - - - - - - - Toluene_X DYD2_k127_2702581_18 926549.KI421517_gene832 1.332e-09 70.0 2CJG0@1|root,332HN@2|Bacteria,4NVWF@976|Bacteroidetes,47SVM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2702581_0 1237149.C900_04731 1.917e-259 805.0 COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,47JTQ@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b DYD2_k127_2702581_16 1237149.C900_02887 7.227e-38 151.0 COG1030@1|root,COG1030@2|Bacteria,4NW09@976|Bacteroidetes,47S4B@768503|Cytophagia 976|Bacteroidetes O NfeD-like C-terminal, partner-binding - - - - - - - - - - - - NfeD DYD2_k127_2702581_4 643867.Ftrac_3711 3.529e-153 489.0 COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia 976|Bacteroidetes S UPF0365 protein - - - - - - - - - - - - YdfA_immunity DYD2_k127_2702581_8 1237149.C900_02886 1.576e-134 454.0 COG0515@1|root,COG0515@2|Bacteria 1237149.C900_02886|- KLT protein kinase activity - - - - - - - - - - - - - DYD2_k127_2702581_9 861299.J421_5972 5.786e-115 384.0 2BS4J@1|root,32M5G@2|Bacteria,1ZUJX@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - DYD2_k127_2702581_15 391612.CY0110_02617 3.467e-40 157.0 COG2068@1|root,COG2068@2|Bacteria,1G608@1117|Cyanobacteria,3KIC2@43988|Cyanothece 1117|Cyanobacteria S MobA-like NTP transferase domain - - 1.1.1.328,2.7.7.76 ko:K07141,ko:K19190 ko00760,ko00790,ko01120,map00760,map00790,map01120 - R10131,R10132,R11582 RC03053 ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD2_k127_2702581_6 1237149.C900_00538 6.174e-137 445.0 COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,47JA8@768503|Cytophagia 976|Bacteroidetes O Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI DYD2_k127_2702581_2 1123278.KB893605_gene1746 4.29e-191 609.0 COG1680@1|root,COG1680@2|Bacteria,4NIG6@976|Bacteroidetes,47KKU@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD2_k127_2702581_3 1237149.C900_00537 6.299e-180 571.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD2_k127_2739569_1 643867.Ftrac_0518 3.19e-86 289.0 COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia 976|Bacteroidetes S UPF0365 protein - - - - - - - - - - - - YdfA_immunity DYD2_k127_2739569_0 867902.Ornrh_1375 9.309e-121 400.0 COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1HXIJ@117743|Flavobacteriia 976|Bacteroidetes L Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C DYD2_k127_2739569_3 1237149.C900_02689 2.867e-31 123.0 COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,47RX4@768503|Cytophagia 976|Bacteroidetes K Cold-shock protein - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD2_k127_2739569_2 1189620.AJXL01000010_gene2582 8.828e-67 231.0 COG0471@1|root,COG0471@2|Bacteria,4NF52@976|Bacteroidetes,1HWTJ@117743|Flavobacteriia,2NVF2@237|Flavobacterium 976|Bacteroidetes P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,TrkA_C DYD2_k127_2743412_1 1313301.AUGC01000001_gene1672 1.658e-66 231.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes 976|Bacteroidetes C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA DYD2_k127_2743412_2 1237149.C900_01197 1.717e-54 194.0 COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes 976|Bacteroidetes S protein conserved in bacteria - - - - - - - - - - - - DUF2147 DYD2_k127_2743412_0 1237149.C900_01196 4.597e-88 293.0 COG1595@1|root,COG1595@2|Bacteria,4NX8R@976|Bacteroidetes,47PIG@768503|Cytophagia 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_ECF,Sigma70_r2 DYD2_k127_2746800_0 1237149.C900_02538 2.882e-183 593.0 COG0508@1|root,COG0508@2|Bacteria,4PKNP@976|Bacteroidetes,47MW8@768503|Cytophagia 976|Bacteroidetes C Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 DYD2_k127_2746800_4 1237149.C900_02539 3.216e-72 248.0 COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,47M9N@768503|Cytophagia 976|Bacteroidetes K Belongs to the UPF0301 (AlgH) family - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 DYD2_k127_2746800_3 1237149.C900_02541 1.825e-83 281.0 COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,47P7A@768503|Cytophagia 976|Bacteroidetes H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx DYD2_k127_2746800_2 1121887.AUDK01000026_gene1956 1.34e-98 327.0 COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1HWWB@117743|Flavobacteriia,2NSSS@237|Flavobacterium 976|Bacteroidetes S GlcNAc-PI de-N-acetylase bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L DYD2_k127_2746800_1 1237149.C900_04237 4.558e-157 499.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,47JQX@768503|Cytophagia 976|Bacteroidetes C Thioredoxin reductase trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD2_k127_2746800_5 1121373.KB903665_gene3045 1.616e-42 156.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD2_k127_2755809_8 1237149.C900_00839 1.018e-51 188.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2755809_3 1123248.KB893321_gene481 1.216e-235 753.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_2755809_4 1121904.ARBP01000004_gene1022 9.406e-189 617.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_2755809_6 865937.Gilli_0451 9.969e-127 420.0 COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1I02U@117743|Flavobacteriia,2P72K@244698|Gillisia 976|Bacteroidetes E Amino acid permease - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 DYD2_k127_2755809_5 1121904.ARBP01000012_gene1293 7.621e-177 574.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria 2|Bacteria P domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N DYD2_k127_2755809_1 1237149.C900_02225 2.761e-255 809.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 2|Bacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_2755809_7 314285.KT71_01450 1.097e-118 390.0 COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RSJA@1236|Gammaproteobacteria,1J7GG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_2755809_2 1237149.C900_00061 3.19e-253 807.0 COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,47MWS@768503|Cytophagia 976|Bacteroidetes E Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 DYD2_k127_2755809_0 1121875.KB907549_gene2068 0.0 1285.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia 976|Bacteroidetes G BNR Asp-box repeat - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_2770795_13 1237149.C900_03811 4.475e-92 310.0 COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes 976|Bacteroidetes HP abc transporter (atp-binding protein) - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran DYD2_k127_2770795_8 1237149.C900_03810 9.149e-100 335.0 COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,47KF2@768503|Cytophagia 976|Bacteroidetes P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD DYD2_k127_2770795_7 1048983.EL17_05030 7.505e-101 331.0 COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,47KMY@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 DYD2_k127_2770795_12 1237149.C900_01037 6.259e-93 308.0 COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,47J8V@768503|Cytophagia 976|Bacteroidetes J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 DYD2_k127_2770795_24 1237149.C900_01038 1.892e-41 154.0 COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,47R4F@768503|Cytophagia 976|Bacteroidetes J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 DYD2_k127_2770795_4 1237149.C900_01039 1.076e-135 436.0 COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,47JS0@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C DYD2_k127_2770795_26 761193.Runsl_1697 7.431e-40 149.0 COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,47QCA@768503|Cytophagia 976|Bacteroidetes J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 DYD2_k127_2770795_22 269798.CHU_3157 9.475e-48 176.0 COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,47QFH@768503|Cytophagia 976|Bacteroidetes J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 DYD2_k127_2770795_6 1237149.C900_01042 3.984e-124 401.0 COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,47MFE@768503|Cytophagia 976|Bacteroidetes J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C DYD2_k127_2770795_15 1123057.P872_23135 1.249e-71 243.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,47P74@768503|Cytophagia 976|Bacteroidetes J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 DYD2_k127_2770795_30 1237149.C900_01044 1.782e-19 89.0 COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,47S5W@768503|Cytophagia 976|Bacteroidetes J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 DYD2_k127_2770795_29 504472.Slin_5778 7.806e-36 137.0 COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,47R6N@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 DYD2_k127_2770795_17 880071.Fleli_2568 1.026e-62 216.0 COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,47PQH@768503|Cytophagia 976|Bacteroidetes J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 DYD2_k127_2770795_23 1237149.C900_01047 4.59e-47 171.0 COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,47R7A@768503|Cytophagia 976|Bacteroidetes J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 DYD2_k127_2770795_10 1237149.C900_01048 6.172e-96 316.0 COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,47KSN@768503|Cytophagia 976|Bacteroidetes J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C DYD2_k127_2770795_27 1434325.AZQN01000006_gene3360 1.773e-38 145.0 COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,47QB0@768503|Cytophagia 976|Bacteroidetes J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 DYD2_k127_2770795_18 1237149.C900_01050 2.573e-61 213.0 COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 DYD2_k127_2770795_14 1124780.ANNU01000035_gene228 1.461e-76 260.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,47PER@768503|Cytophagia 976|Bacteroidetes J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 DYD2_k127_2770795_25 880070.Cycma_2605 4.859e-41 154.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,47RC9@768503|Cytophagia 976|Bacteroidetes J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p DYD2_k127_2770795_11 1237149.C900_01053 4.751e-93 306.0 COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,47M7G@768503|Cytophagia 976|Bacteroidetes J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C DYD2_k127_2770795_31 153721.MYP_1346 2.31e-18 85.0 COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,47S6M@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 DYD2_k127_2770795_21 1237149.C900_01055 2.06e-54 194.0 COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,47PP0@768503|Cytophagia 976|Bacteroidetes J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A DYD2_k127_2770795_1 1237149.C900_01056 1.803e-224 701.0 COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,47JRD@768503|Cytophagia 976|Bacteroidetes U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY DYD2_k127_2770795_5 1237149.C900_01057 2.6e-127 411.0 COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,47KDT@768503|Cytophagia 976|Bacteroidetes E TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD2_k127_2770795_28 714943.Mucpa_2087 3.905e-36 137.0 COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,1IT95@117747|Sphingobacteriia 976|Bacteroidetes J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a DYD2_k127_2770795_32 1150600.ADIARSV_3606 7.536e-15 74.0 COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,1IUD9@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 DYD2_k127_2770795_19 269798.CHU_3139 1.356e-59 208.0 COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,47PRH@768503|Cytophagia 976|Bacteroidetes J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 DYD2_k127_2770795_16 761193.Runsl_1676 4.712e-64 221.0 COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,47Q07@768503|Cytophagia 976|Bacteroidetes J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 DYD2_k127_2770795_9 1237149.C900_01062 9.561e-97 319.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,47K3X@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 DYD2_k127_2770795_3 1237149.C900_01063 4.549e-179 564.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,47JD5@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L DYD2_k127_2770795_20 929556.Solca_2999 1.597e-55 199.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,1IRYB@117747|Sphingobacteriia 976|Bacteroidetes J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 DYD2_k127_2770795_2 1237149.C900_01065 1.577e-185 586.0 COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,47KT4@768503|Cytophagia 976|Bacteroidetes F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase DYD2_k127_2770795_0 1237149.C900_01066 9.864e-239 741.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia 976|Bacteroidetes G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N DYD2_k127_2778218_1 1120965.AUBV01000001_gene3537 2.694e-120 390.0 COG0251@1|root,COG0667@1|root,COG0251@2|Bacteria,COG0667@2|Bacteria,4P1NX@976|Bacteroidetes,47XV2@768503|Cytophagia 976|Bacteroidetes CJ Endoribonuclease L-PSP - - - - - - - - - - - - Aldo_ket_red,Ribonuc_L-PSP DYD2_k127_2778218_0 1237149.C900_00885 1.064e-218 695.0 COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,47NWB@768503|Cytophagia 976|Bacteroidetes S M61 glycyl aminopeptidase - - - - - - - - - - - - Peptidase_M61 DYD2_k127_2778218_2 760192.Halhy_0173 1.251e-45 169.0 COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1IWK9@117747|Sphingobacteriia 976|Bacteroidetes E Phosphotransferase enzyme family - - - - - - - - - - - - APH,Aminotran_3,Peptidase_M23 DYD2_k127_2817064_18 1124780.ANNU01000064_gene435 2.694e-26 110.0 COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,47K5Q@768503|Cytophagia 976|Bacteroidetes F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin DYD2_k127_2817064_2 1237149.C900_02255 1.038e-205 648.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,47M23@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA - 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB DYD2_k127_2817064_6 1239962.C943_02668 3.2e-175 557.0 COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,47ND4@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrB - 1.6.5.8 ko:K00347 - - - - ko00000,ko01000 - - - NQR2_RnfD_RnfE DYD2_k127_2817064_13 1237149.C900_02251 6.175e-76 262.0 COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,47TVG@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC - 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind DYD2_k127_2817064_11 1237149.C900_02250 1.149e-102 337.0 COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,47P80@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD - 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr DYD2_k127_2817064_12 1237149.C900_02249 8.584e-102 334.0 COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,47KRI@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrE - 1.6.5.8 ko:K00350 - - - - ko00000,ko01000 - - - Rnf-Nqr DYD2_k127_2817064_15 1124780.ANNU01000064_gene442 5.203e-51 186.0 COG2928@1|root,COG2928@2|Bacteria,4NR4F@976|Bacteroidetes,47QB1@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 DYD2_k127_2817064_5 1237149.C900_02247 3.078e-189 597.0 COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,47KX3@768503|Cytophagia 976|Bacteroidetes J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans DYD2_k127_2817064_9 1124780.ANNU01000024_gene3114 5.147e-127 417.0 COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin DYD2_k127_2817064_8 1237149.C900_02241 1.345e-132 432.0 COG1804@1|root,COG1804@2|Bacteria,4NEA8@976|Bacteroidetes,47NJE@768503|Cytophagia 976|Bacteroidetes C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 DYD2_k127_2817064_14 1237149.C900_02239 5.223e-71 243.0 COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,47Q53@768503|Cytophagia 976|Bacteroidetes K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ DYD2_k127_2817064_10 643867.Ftrac_3286 4.8e-121 395.0 COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,47JJ6@768503|Cytophagia 976|Bacteroidetes J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 DYD2_k127_2817064_17 1237149.C900_02237 1.196e-32 130.0 2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,47R7E@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2817064_0 1237149.C900_02236 9.088e-310 962.0 COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,47K6U@768503|Cytophagia 976|Bacteroidetes M Cell division protein FtsI penicillin-binding protein 2 ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PASTA,PBP_dimer,Transpeptidase DYD2_k127_2817064_1 1237149.C900_02235 1.414e-220 693.0 COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,47JT3@768503|Cytophagia 976|Bacteroidetes M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD2_k127_2817064_3 1237149.C900_02234 8.363e-205 643.0 COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,47KEP@768503|Cytophagia 976|Bacteroidetes M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 DYD2_k127_2817064_7 1237149.C900_02233 2.71e-163 526.0 COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,47KTX@768503|Cytophagia 976|Bacteroidetes M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M DYD2_k127_2817064_4 1237149.C900_02232 4.615e-194 611.0 COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,47K3R@768503|Cytophagia 976|Bacteroidetes D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE DYD2_k127_2817064_16 313603.FB2170_16921 3.738e-34 132.0 COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,1HXPU@117743|Flavobacteriia,2PG16@252356|Maribacter 976|Bacteroidetes M Glycosyltransferase family 28 N-terminal domain murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 DYD2_k127_2844598_0 760192.Halhy_4111 0.0 1240.0 COG4447@1|root,COG4447@2|Bacteria,4NK5F@976|Bacteroidetes,1IWI3@117747|Sphingobacteriia 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - - DYD2_k127_2844598_1 1237149.C900_03615 3.186e-63 222.0 arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia 976|Bacteroidetes S lycopene cyclase - - - - - - - - - - - - - DYD2_k127_2859225_1 1237149.C900_05622 1.124e-62 220.0 COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia 976|Bacteroidetes C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ DYD2_k127_2859225_0 1237149.C900_05621 2.929e-272 847.0 COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,47T90@768503|Cytophagia 976|Bacteroidetes F Formate--tetrahydrofolate ligase fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS DYD2_k127_2859225_2 1268237.G114_08682 2.959e-47 175.0 COG4123@1|root,COG4123@2|Bacteria,1PC8R@1224|Proteobacteria,1RM8S@1236|Gammaproteobacteria,1Y4BN@135624|Aeromonadales 135624|Aeromonadales J Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - 2.1.1.223 ko:K15460 - - - - ko00000,ko01000,ko03016 - - - MTS DYD2_k127_2909514_13 1237149.C900_00769 2.137e-39 152.0 COG2972@1|root,COG2972@2|Bacteria,4NMUF@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase DYD2_k127_2909514_12 880070.Cycma_0052 9.226e-42 157.0 29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes,47T83@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 DYD2_k127_2909514_18 1237149.C900_03399 1.127e-23 106.0 28WK7@1|root,2ZIK7@2|Bacteria,4P8ND@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2909514_20 1121124.JNIX01000016_gene2071 1.088e-08 68.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2KG4I@204458|Caulobacterales 204458|Caulobacterales QU Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,PD40 DYD2_k127_2909514_8 204669.Acid345_2285 1.497e-77 269.0 COG0491@1|root,COG0491@2|Bacteria,3Y3UW@57723|Acidobacteria,2JK4T@204432|Acidobacteriia 204432|Acidobacteriia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD2_k127_2909514_2 1189612.A33Q_0281 4.495e-151 489.0 COG0436@1|root,COG0436@2|Bacteria,4NJEW@976|Bacteroidetes,47TQQ@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 DYD2_k127_2909514_17 1121930.AQXG01000017_gene3138 4.425e-30 128.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_N DYD2_k127_2909514_6 313606.M23134_01615 5.079e-87 294.0 COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,47SW9@768503|Cytophagia 976|Bacteroidetes M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like DYD2_k127_2909514_3 1408473.JHXO01000005_gene1473 1.714e-114 381.0 COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,2FS1D@200643|Bacteroidia 976|Bacteroidetes M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2909514_4 1313421.JHBV01000042_gene3354 4.452e-96 328.0 COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1IVIT@117747|Sphingobacteriia 976|Bacteroidetes M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2909514_5 1279009.ADICEAN_02875 3.863e-89 299.0 COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,47TWR@768503|Cytophagia 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_2909514_7 1313421.JHBV01000042_gene3356 5.708e-83 290.0 2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes,1IWDH@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_2909514_15 1443665.JACA01000013_gene4278 7.095e-33 132.0 COG0454@1|root,COG0456@2|Bacteria,4NSKG@976|Bacteroidetes,1I9KP@117743|Flavobacteriia,2YJJU@290174|Aquimarina 976|Bacteroidetes K Acetyltransferase (GNAT) domain phnO - - ko:K09994 ko00440,map00440 - R11479 RC00096 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 DYD2_k127_2909514_11 1121373.KB903632_gene485 1.1e-56 202.0 COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,47QKE@768503|Cytophagia 976|Bacteroidetes K Cold shock protein domain cspG - - - - - - - - - - - CSD DYD2_k127_2909514_0 313603.FB2170_11651 0.0 1462.0 COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI8X@252356|Maribacter 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_2909514_9 1237149.C900_04983 8.72e-69 246.0 COG4978@1|root,COG4978@2|Bacteria 2|Bacteria - - MA20_43725 - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like DYD2_k127_2909514_14 1121904.ARBP01000003_gene6259 1.565e-33 132.0 2E4GE@1|root,32ZBK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_2909514_1 269798.CHU_1404 3.512e-193 621.0 COG0362@1|root,COG3265@1|root,COG0362@2|Bacteria,COG3265@2|Bacteria,4NG05@976|Bacteroidetes,47NDJ@768503|Cytophagia 976|Bacteroidetes G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH - - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2,SKI DYD2_k127_2909514_10 655815.ZPR_2583 7.125e-62 218.0 COG2610@1|root,COG2610@2|Bacteria,4NFBD@976|Bacteroidetes,1HY9I@117743|Flavobacteriia 976|Bacteroidetes EG H gluconate symporter and related - - - ko:K03299,ko:K06156 - - - - ko00000,ko02000 2.A.8,2.A.8.1.8 - - GntP_permease DYD2_k127_2957588_1 1237149.C900_04771 4.014e-63 220.0 COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,47KX5@768503|Cytophagia 976|Bacteroidetes H Nicotinate-nucleotide adenylyltransferase - - - - - - - - - - - - - DYD2_k127_2957588_0 1237149.C900_04780 8.843e-253 790.0 COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,47K1E@768503|Cytophagia 976|Bacteroidetes IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD2_k127_2962452_15 583355.Caka_1194 1.466e-07 53.0 COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,3K87F@414999|Opitutae 414999|Opitutae S RNA recognition motif - - - - - - - - - - - - RRM_1 DYD2_k127_2962452_2 1239962.C943_00383 6.24e-282 888.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_2962452_12 1123278.KB893433_gene687 4.786e-62 216.0 COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,47K8K@768503|Cytophagia 976|Bacteroidetes E PFAM FAD dependent oxidoreductase dadA - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO DYD2_k127_2962452_9 1185876.BN8_05504 1.024e-84 287.0 COG0665@1|root,COG0665@2|Bacteria,4NEUE@976|Bacteroidetes,47K8K@768503|Cytophagia 976|Bacteroidetes E PFAM FAD dependent oxidoreductase dadA - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO DYD2_k127_2962452_3 1237149.C900_05557 1.088e-185 584.0 COG3938@1|root,COG3938@2|Bacteria,4NHJZ@976|Bacteroidetes,47KV9@768503|Cytophagia 976|Bacteroidetes E Belongs to the proline racemase family - - 5.1.1.8 ko:K12658 ko00330,map00330 - R03296 RC00479 ko00000,ko00001,ko01000 - - - Pro_racemase DYD2_k127_2962452_4 929703.KE386491_gene3160 2.432e-181 580.0 COG1012@1|root,COG1012@2|Bacteria,4NEKG@976|Bacteroidetes,47MQT@768503|Cytophagia 976|Bacteroidetes C PFAM Aldehyde dehydrogenase aldH - 1.2.1.26 ko:K13877 ko00040,ko00053,map00040,map00053 - R00264 RC00080 ko00000,ko00001,ko01000 - - - Aldedh DYD2_k127_2962452_6 485918.Cpin_5586 6.615e-142 455.0 COG0329@1|root,COG0329@2|Bacteria,4NF2Z@976|Bacteroidetes,1IQRX@117747|Sphingobacteriia 976|Bacteroidetes EM Belongs to the DapA family - - 3.5.4.22,4.3.3.7 ko:K01714,ko:K21062 ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R02280,R10147 RC00679,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD2_k127_2962452_5 1237149.C900_01635 2.48e-174 555.0 COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07098 - - - - ko00000 - - - Metallophos DYD2_k127_2962452_1 1237149.C900_01636 0.0 1478.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47ME1@768503|Cytophagia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran DYD2_k127_2962452_8 1237149.C900_01637 1.503e-111 373.0 COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47MFI@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 DYD2_k127_2962452_7 1237149.C900_01638 3.767e-126 418.0 COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,47KE9@768503|Cytophagia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP DYD2_k127_2962452_10 1237149.C900_01639 9.176e-72 248.0 COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,47QGN@768503|Cytophagia 976|Bacteroidetes K PFAM Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N DYD2_k127_2962452_13 1237149.C900_01641 2.932e-52 190.0 COG1595@1|root,COG1595@2|Bacteria,4NN4K@976|Bacteroidetes,47QDX@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family fecI - - - - - - - - - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD2_k127_2962452_11 643867.Ftrac_0548 1.574e-70 251.0 COG2267@1|root,COG2267@2|Bacteria,4NPD2@976|Bacteroidetes,47XYA@768503|Cytophagia 976|Bacteroidetes I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 DYD2_k127_2962452_0 1237149.C900_01647 0.0 1575.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,47NAM@768503|Cytophagia 976|Bacteroidetes F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 DYD2_k127_29811_1 1121904.ARBP01000001_gene5480 3.091e-153 494.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia 976|Bacteroidetes EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 DYD2_k127_29811_0 1313301.AUGC01000001_gene1409 2.154e-219 687.0 COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes 976|Bacteroidetes C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD2_k127_29811_5 1237149.C900_02945 2.614e-68 237.0 COG2340@1|root,COG2340@2|Bacteria,4NRNN@976|Bacteroidetes,47RRN@768503|Cytophagia 976|Bacteroidetes S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP DYD2_k127_29811_2 1237149.C900_02882 1.317e-145 464.0 COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,47K8P@768503|Cytophagia 976|Bacteroidetes H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf DYD2_k127_29811_6 1237149.C900_02880 1.93e-52 190.0 COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,47QMM@768503|Cytophagia 976|Bacteroidetes F Pyrimidine operon attenuation protein uracil phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran DYD2_k127_29811_4 1237149.C900_02879 6.424e-70 239.0 COG1522@1|root,COG1522@2|Bacteria,4NMYA@976|Bacteroidetes,47P8E@768503|Cytophagia 976|Bacteroidetes K transcriptional regulator - - - ko:K03719,ko:K05800 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24 DYD2_k127_29811_3 1237149.C900_02878 6.285e-122 421.0 COG3291@1|root,COG3291@2|Bacteria,4NPCA@976|Bacteroidetes,47S64@768503|Cytophagia 976|Bacteroidetes S PKD domain - - - - - - - - - - - - PKD DYD2_k127_3015353_15 1121104.AQXH01000004_gene10 6.418e-07 51.0 COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 DYD2_k127_3015353_12 313606.M23134_07794 2.768e-28 114.0 COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,47S6V@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 DYD2_k127_3015353_14 1237149.C900_01753 6.39e-15 75.0 2E359@1|root,32P2Z@2|Bacteria,4NWAD@976|Bacteroidetes,47SNB@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4295) - - - - - - - - - - - - DUF4295 DYD2_k127_3015353_4 1237149.C900_01754 1.653e-170 539.0 COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,47JVI@768503|Cytophagia 976|Bacteroidetes U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N DYD2_k127_3015353_10 1237149.C900_01757 7.328e-44 168.0 28JHY@1|root,2Z9BE@2|Bacteria,4NVN1@976|Bacteroidetes,47SUR@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3015353_2 643867.Ftrac_1929 2.341e-223 698.0 COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,47JJ2@768503|Cytophagia 976|Bacteroidetes J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 DYD2_k127_3015353_5 1237149.C900_01760 1.739e-166 538.0 COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,47JYH@768503|Cytophagia 976|Bacteroidetes S Belongs to the BshC family bshC - - ko:K22136 - - - - ko00000 - - - BshC DYD2_k127_3015353_9 1124780.ANNU01000018_gene1631 4.519e-46 172.0 COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,47Q5G@768503|Cytophagia 976|Bacteroidetes H 5-formyltetrahydrofolate cyclo-ligase family ygfA - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig DYD2_k127_3015353_7 1123278.KB893499_gene320 7.804e-63 243.0 COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,47M8I@768503|Cytophagia 976|Bacteroidetes S Large extracellular alpha-helical protein - - - - - - - - - - - - - DYD2_k127_3015353_11 1185876.BN8_01292 6.969e-35 147.0 28I8D@1|root,2ZBHJ@2|Bacteria,4NHI9@976|Bacteroidetes,47KUP@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 DYD2_k127_3015353_1 926549.KI421517_gene2060 4.66e-227 734.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47JN3@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_3015353_8 1197477.IA57_08610 1.744e-55 204.0 COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,1HZG3@117743|Flavobacteriia 976|Bacteroidetes S S-adenosyl-L-methionine-dependent methyltransferase mnmC - - - - - - - - - - - Methyltransf_30 DYD2_k127_3015353_6 153721.MYP_1243 4.293e-68 234.0 COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,47PDR@768503|Cytophagia 976|Bacteroidetes I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB DYD2_k127_3015353_3 643867.Ftrac_2816 7.332e-178 565.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47JGY@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD2_k127_3015353_0 1237149.C900_01769 0.0 1008.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia 976|Bacteroidetes C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit bfmBA - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C DYD2_k127_3038750_9 945713.IALB_0205 4.911e-57 202.0 COG0225@1|root,COG0225@2|Bacteria 2|Bacteria O peptide-methionine (S)-S-oxide reductase activity msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR DYD2_k127_3038750_8 1237149.C900_04349 4.112e-84 292.0 COG0457@1|root,COG0457@2|Bacteria,4PJN4@976|Bacteroidetes,47NZ0@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - DYD2_k127_3038750_7 1519464.HY22_13050 1.63e-91 315.0 COG2382@1|root,COG2382@2|Bacteria 2|Bacteria P enterobactin catabolic process yjcH - - ko:K07214 - - - - ko00000 - - - Esterase DYD2_k127_3038750_6 696369.KI912183_gene2345 3.536e-108 354.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia,263ZF@186807|Peptococcaceae 186801|Clostridia U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - iHN637.CLJU_RS07630 MIP DYD2_k127_3038750_2 1120973.AQXL01000135_gene1433 1.781e-233 730.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,278ZG@186823|Alicyclobacillaceae 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK - 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N DYD2_k127_3038750_5 1349785.BAUG01000035_gene1929 3.491e-193 616.0 COG0578@1|root,COG0578@2|Bacteria,4PKIZ@976|Bacteroidetes,1IJMF@117743|Flavobacteriia 976|Bacteroidetes C C-terminal domain of alpha-glycerophosphate oxidase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C DYD2_k127_3038750_11 1267211.KI669560_gene259 1.902e-28 119.0 COG4654@1|root,COG4654@2|Bacteria,4NSJC@976|Bacteroidetes,1ITX4@117747|Sphingobacteriia 976|Bacteroidetes C Cytochrome c - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C,Cytochrome_CBB3 DYD2_k127_3038750_0 1237149.C900_05130 4.652e-281 871.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,47JC3@768503|Cytophagia 976|Bacteroidetes H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP DYD2_k127_3038750_3 1237149.C900_03836 1.419e-217 685.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity putP_2 - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF DYD2_k127_3038750_4 215803.DB30_7386 3.767e-205 657.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales 28221|Deltaproteobacteria S oligopeptide transporter, OPT family - - - - - - - - - - - - OPT DYD2_k127_3038750_1 1237149.C900_05125 8.974e-279 864.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,47JYW@768503|Cytophagia 976|Bacteroidetes O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD2_k127_3038750_10 1237149.C900_05124 8.512e-37 139.0 COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia 976|Bacteroidetes O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD2_k127_3042027_6 880071.Fleli_0020 1.141e-52 200.0 COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes,47XFE@768503|Cytophagia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA DYD2_k127_3042027_0 1121904.ARBP01000006_gene3853 0.0 1611.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia 976|Bacteroidetes EF PFAM Carbamoyl-phosphate synthase L chain, ATP binding carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS DYD2_k127_3042027_2 760192.Halhy_4130 4.357e-168 537.0 COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia 976|Bacteroidetes E Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 DYD2_k127_3042027_8 485917.Phep_3698 1.16e-34 134.0 COG4892@1|root,COG4892@2|Bacteria,4NSAM@976|Bacteroidetes,1IYRW@117747|Sphingobacteriia 976|Bacteroidetes S Cytochrome b5-like Heme/Steroid binding domain - - - - - - - - - - - - Cyt-b5 DYD2_k127_3042027_5 1237149.C900_01166 2.346e-93 314.0 COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,47MGQ@768503|Cytophagia 976|Bacteroidetes G N-acetylglucosamine kinase - - - - - - - - - - - - BcrAD_BadFG DYD2_k127_3042027_4 1121904.ARBP01000010_gene2258 1.336e-116 380.0 COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,47K6T@768503|Cytophagia 976|Bacteroidetes G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS DYD2_k127_3042027_7 926556.Echvi_0812 6.832e-49 181.0 COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,47QAA@768503|Cytophagia 976|Bacteroidetes S PFAM SprT-like family sprT - - - - - - - - - - - SprT-like DYD2_k127_3042027_1 1279009.ADICEAN_02693 7.131e-203 638.0 COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,47K6M@768503|Cytophagia 976|Bacteroidetes S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 DYD2_k127_3042027_3 1124780.ANNU01000017_gene1972 4.204e-119 390.0 COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,47K35@768503|Cytophagia 976|Bacteroidetes S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 DYD2_k127_3042027_9 1237149.C900_03859 6.623e-33 130.0 COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,47KXF@768503|Cytophagia 976|Bacteroidetes E Threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase DYD2_k127_305956_3 1237149.C900_01034 1.364e-174 572.0 COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,47M4V@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop DYD2_k127_305956_11 1237149.C900_01035 5.583e-63 223.0 COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia 976|Bacteroidetes L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N DYD2_k127_305956_10 1237149.C900_04521 1.779e-82 280.0 COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,47PED@768503|Cytophagia 976|Bacteroidetes K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C DYD2_k127_305956_5 1237149.C900_04522 2.905e-144 468.0 COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47M71@768503|Cytophagia 976|Bacteroidetes T Signal transduction histidine kinase rprX - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD2_k127_305956_13 1434325.AZQN01000010_gene3892 5.363e-34 135.0 2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,47QC0@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 DYD2_k127_305956_7 1237149.C900_02789 8.277e-102 337.0 COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,47MAX@768503|Cytophagia 976|Bacteroidetes S NADP oxidoreductase coenzyme F420-dependent - - - - - - - - - - - - DUF2520,F420_oxidored,Rossmann-like DYD2_k127_305956_2 1453500.AT05_07455 1.349e-187 595.0 COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,1HWJT@117743|Flavobacteriia 976|Bacteroidetes C acetyl-CoA hydrolase - - - - - - - - - - - - AcetylCoA_hyd_C,AcetylCoA_hydro DYD2_k127_305956_4 1237149.C900_00369 1.504e-161 516.0 COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,47MAZ@768503|Cytophagia 976|Bacteroidetes E PFAM aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 DYD2_k127_305956_1 643867.Ftrac_2642 2.396e-204 644.0 COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,47KR9@768503|Cytophagia 976|Bacteroidetes G Phosphoglucomutase phosphomannomutase alpha beta alpha domain I glmM - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD2_k127_305956_14 1237149.C900_00372 5.141e-22 97.0 2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,47S69@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_305956_6 1237149.C900_00373 4.215e-125 405.0 COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,47K4M@768503|Cytophagia 976|Bacteroidetes S PFAM MazG nucleotide pyrophosphohydrolase mazG - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - MazG DYD2_k127_305956_8 1144313.PMI10_01898 1.176e-101 347.0 COG4251@1|root,COG4251@2|Bacteria,4NJM0@976|Bacteroidetes,1IING@117743|Flavobacteriia,2NU2M@237|Flavobacterium 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA DYD2_k127_305956_0 1237149.C900_04608 1.891e-237 761.0 COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia 976|Bacteroidetes M AsmA-like C-terminal region - - - - - - - - - - - - AsmA,AsmA_2,DUF3971 DYD2_k127_305956_12 216432.CA2559_02185 1.21e-57 206.0 COG1309@1|root,COG1309@2|Bacteria,4NH7V@976|Bacteroidetes,1HYMJ@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - TetR_C_13,TetR_C_4,TetR_N DYD2_k127_305956_9 1279009.ADICEAN_01623 3.718e-87 297.0 COG1073@1|root,COG1073@2|Bacteria,4NGDK@976|Bacteroidetes,47Q3Y@768503|Cytophagia 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4 DYD2_k127_3063880_23 643867.Ftrac_2359 2.61e-07 53.0 COG0526@1|root,COG0526@2|Bacteria,4P4VR@976|Bacteroidetes,47VN1@768503|Cytophagia 976|Bacteroidetes O Thioredoxin-like - - - - - - - - - - - - - DYD2_k127_3063880_1 1237149.C900_03353 8.662e-294 907.0 COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,47J97@768503|Cytophagia 976|Bacteroidetes S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn DYD2_k127_3063880_19 927658.AJUM01000047_gene2761 5.644e-40 155.0 COG1846@1|root,COG1846@2|Bacteria,4NRNH@976|Bacteroidetes,2G26Q@200643|Bacteroidia,3XK68@558415|Marinilabiliaceae 976|Bacteroidetes K MarR family - - - - - - - - - - - - MarR DYD2_k127_3063880_4 1123368.AUIS01000030_gene1244 6.441e-190 604.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria 1236|Gammaproteobacteria C lysine 2,3-aminomutase - - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,LAM_C,Radical_SAM DYD2_k127_3063880_6 290318.Cvib_1366 5.371e-171 548.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF DYD2_k127_3063880_12 931626.Awo_c03840 9.04e-69 243.0 COG0454@1|root,COG0456@2|Bacteria,1V62Y@1239|Firmicutes,25DXX@186801|Clostridia 186801|Clostridia K beta-lysine N-acetyltransferase - - 2.3.1.264 ko:K21935 - - R11701 - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 DYD2_k127_3063880_17 1123277.KB893174_gene5902 6.888e-48 173.0 COG1695@1|root,COG1695@2|Bacteria,4P3EW@976|Bacteroidetes,47V29@768503|Cytophagia 976|Bacteroidetes K PFAM transcriptional regulator PadR family protein - - - - - - - - - - - - PadR DYD2_k127_3063880_2 1123277.KB893174_gene5903 1.222e-249 797.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_3063880_5 264462.Bd2070 2.196e-176 561.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2MSTM@213481|Bdellovibrionales,2WJB2@28221|Deltaproteobacteria 213481|Bdellovibrionales I Belongs to the thiolase family fadI - 2.3.1.16,2.3.1.9 ko:K00626,ko:K00632 ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00087,M00088,M00095,M00113,M00373,M00374,M00375 R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD2_k127_3063880_14 929556.Solca_0144 1.113e-62 222.0 COG3571@1|root,COG3571@2|Bacteria,4NEGG@976|Bacteroidetes,1IUJ8@117747|Sphingobacteriia 976|Bacteroidetes S Alpha/beta hydrolase family - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_5 DYD2_k127_3063880_11 1286632.P278_15660 1.383e-83 284.0 COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,1HZ1Z@117743|Flavobacteriia 976|Bacteroidetes G COG2273 Beta-glucanase Beta-glucan synthetase - - - - - - - - - - - - Glyco_hydro_16 DYD2_k127_3063880_9 566466.NOR53_2256 9.446e-113 375.0 COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,1RQPZ@1236|Gammaproteobacteria,1J6PZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Integral membrane protein - - - - - - - - - - - - DUF819 DYD2_k127_3063880_16 1250005.PHEL85_1282 1.192e-55 199.0 COG0664@1|root,COG0664@2|Bacteria,4NNIX@976|Bacteroidetes,1I247@117743|Flavobacteriia 976|Bacteroidetes T CRP FNR family transcriptional regulator - - - - - - - - - - - - cNMP_binding DYD2_k127_3063880_15 1121904.ARBP01000013_gene351 1.203e-58 208.0 COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes,47Q0U@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 DYD2_k127_3063880_22 1218108.KB908301_gene2391 2.71e-28 121.0 2E4AP@1|root,32Z6C@2|Bacteria,4NWDP@976|Bacteroidetes,1I55P@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3063880_20 714943.Mucpa_0352 2.291e-34 133.0 COG3369@1|root,COG3369@2|Bacteria,4NSK8@976|Bacteroidetes,1IYH3@117747|Sphingobacteriia 976|Bacteroidetes S Iron-binding zinc finger CDGSH type - - - - - - - - - - - - zf-CDGSH DYD2_k127_3063880_3 641524.ADICYQ_5574 1.084e-209 655.0 COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,47MDV@768503|Cytophagia 976|Bacteroidetes S PFAM Amidohydrolase 2 - - - - - - - - - - - - Amidohydro_2 DYD2_k127_3063880_13 641524.ADICYQ_5575 9.923e-64 223.0 COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 DYD2_k127_3063880_0 504472.Slin_3267 5.218e-318 987.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia 976|Bacteroidetes EU Dienelactone hydrolase family - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9 DYD2_k127_3063880_21 1379270.AUXF01000001_gene2079 1.775e-32 132.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - ABM,DUF3225,DUF4440,SnoaL_2,SnoaL_3 DYD2_k127_3063880_18 794903.OPIT5_11735 1.295e-43 168.0 COG0500@1|root,COG0500@2|Bacteria,46V7N@74201|Verrucomicrobia,3K8BC@414999|Opitutae 414999|Opitutae Q methyltransferase - - - - - - - - - - - - Methyltransf_25 DYD2_k127_3063880_10 1249997.JHZW01000002_gene401 3.749e-87 294.0 COG0664@1|root,COG0664@2|Bacteria,4PMAC@976|Bacteroidetes,1HXBX@117743|Flavobacteriia,2PI8R@252356|Maribacter 976|Bacteroidetes T Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans DYD2_k127_3063880_8 1279009.ADICEAN_01274 2.029e-135 456.0 COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia 976|Bacteroidetes MU OmpA family - - - - - - - - - - - - OmpA,PD40 DYD2_k127_3063880_7 1237149.C900_04488 1.175e-169 552.0 COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,47NX3@768503|Cytophagia 976|Bacteroidetes P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N DYD2_k127_3098007_3 643867.Ftrac_2367 1.902e-47 182.0 COG0596@1|root,COG0596@2|Bacteria,4PNPN@976|Bacteroidetes,47XAU@768503|Cytophagia 976|Bacteroidetes S Ndr family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 DYD2_k127_3098007_1 388413.ALPR1_02505 5.424e-167 531.0 COG3507@1|root,COG3507@2|Bacteria,4NEIZ@976|Bacteroidetes,47KME@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolases family 43 - - - - - - - - - - - - Glyco_hydro_43 DYD2_k127_3098007_0 886377.Murru_1087 3.856e-174 552.0 COG0673@1|root,COG0673@2|Bacteria,4NFGY@976|Bacteroidetes,1HZUQ@117743|Flavobacteriia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_3098007_4 1121904.ARBP01000030_gene1963 1.424e-44 164.0 COG1695@1|root,COG1695@2|Bacteria,4NUDG@976|Bacteroidetes 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR DYD2_k127_3098007_2 926549.KI421517_gene2412 5.776e-147 480.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_3107846_6 1237149.C900_04649 3.979e-120 388.0 COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,47KH2@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_3107846_5 1237149.C900_04650 1.471e-187 592.0 COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JQD@768503|Cytophagia 976|Bacteroidetes I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N DYD2_k127_3107846_9 385682.AFSL01000088_gene845 5.641e-49 177.0 2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,2G1K9@200643|Bacteroidia,3XKZH@558415|Marinilabiliaceae 976|Bacteroidetes S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP DYD2_k127_3107846_0 1237149.C900_04651 0.0 1289.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,47ME4@768503|Cytophagia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 DYD2_k127_3107846_8 1237149.C900_04652 1.011e-56 201.0 COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,47QHS@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR DYD2_k127_3107846_4 1124780.ANNU01000023_gene3232 2.377e-202 642.0 COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MR6@768503|Cytophagia 976|Bacteroidetes G PFAM Alpha amylase, catalytic - GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070 3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54 ko:K01176,ko:K01208 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,BACON,DUF3459 DYD2_k127_3107846_2 985255.APHJ01000021_gene1603 3.643e-223 699.0 COG0477@1|root,COG0477@2|Bacteria,4PKTJ@976|Bacteroidetes,1IJGN@117743|Flavobacteriia,2P5NK@244698|Gillisia 976|Bacteroidetes EGP Sugar (and other) transporter - - - ko:K08138 - - - - ko00000,ko02000 2.A.1.1.3 - - Sugar_tr DYD2_k127_3107846_3 1122137.AQXF01000007_gene3610 5.624e-204 647.0 COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,2TUK8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF DYD2_k127_3107846_1 1121904.ARBP01000015_gene179 8.148e-259 820.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_3107846_7 1120966.AUBU01000006_gene3140 2.227e-86 289.0 COG2860@1|root,COG2860@2|Bacteria,4NEXS@976|Bacteroidetes,47KVV@768503|Cytophagia 976|Bacteroidetes S UPF0126 domain - - - - - - - - - - - - UPF0126 DYD2_k127_3107846_10 1120965.AUBV01000006_gene2152 1.169e-22 98.0 COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47N6X@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C DYD2_k127_3148353_0 313606.M23134_06281 2.185e-79 286.0 COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NSC3@976|Bacteroidetes,47S66@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14,TPR_2 DYD2_k127_3148353_1 632245.CLP_2390 2.823e-48 180.0 COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,36VHQ@31979|Clostridiaceae 186801|Clostridia S Succinylglutamate desuccinylase aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA,Methyltransf_11 DYD2_k127_3162098_4 1089547.KB913013_gene2090 1.275e-96 317.0 COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,47K3S@768503|Cytophagia 976|Bacteroidetes M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD2_k127_3162098_2 471854.Dfer_2896 1.236e-147 471.0 COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,47JPC@768503|Cytophagia 976|Bacteroidetes M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD2_k127_3162098_3 1237149.C900_01777 1.35e-124 408.0 COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,47KMC@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase family M28 ywaD - - - - - - - - - - - Peptidase_M28 DYD2_k127_3162098_5 1237149.C900_01778 3.58e-33 134.0 COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,47R9C@768503|Cytophagia 976|Bacteroidetes S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C DYD2_k127_3162098_1 1237149.C900_01779 4.088e-226 704.0 COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,47KFI@768503|Cytophagia 976|Bacteroidetes K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 DYD2_k127_3162098_0 643867.Ftrac_2449 4.545e-227 720.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,47KGB@768503|Cytophagia 976|Bacteroidetes J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N DYD2_k127_316823_30 1107311.Q767_00390 4.531e-21 103.0 COG1520@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4PPGQ@976|Bacteroidetes,1IKMC@117743|Flavobacteriia,2NUKU@237|Flavobacterium 976|Bacteroidetes G Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - SBBP DYD2_k127_316823_22 1185876.BN8_05686 9.104e-64 222.0 COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 DYD2_k127_316823_14 1237149.C900_04098 7.53e-102 337.0 COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,47PND@768503|Cytophagia 976|Bacteroidetes M Cell wall-associated hydrolase (invasion-associated protein) ykfC - - - - - - - - - - - NLPC_P60,SH3_3 DYD2_k127_316823_23 1237149.C900_04099 1.241e-62 218.0 COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,47PRC@768503|Cytophagia 976|Bacteroidetes J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB DYD2_k127_316823_27 1124780.ANNU01000040_gene393 4.26e-41 155.0 COG5496@1|root,COG5496@2|Bacteria,4P643@976|Bacteroidetes,47VXQ@768503|Cytophagia 976|Bacteroidetes S Thioesterase - - - - - - - - - - - - - DYD2_k127_316823_6 1237149.C900_04101 1.15e-150 483.0 COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia 976|Bacteroidetes O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 DYD2_k127_316823_0 1237149.C900_04102 0.0 1294.0 COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47KQP@768503|Cytophagia 976|Bacteroidetes S PFAM Family of - - - - - - - - - - - - TamB DYD2_k127_316823_15 313606.M23134_00725 9.625e-88 299.0 COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,47JQY@768503|Cytophagia 976|Bacteroidetes S Predicted periplasmic lipoprotein (DUF2279) - - - - - - - - - - - - DUF2279 DYD2_k127_316823_28 1237149.C900_04104 7.862e-32 131.0 2E6VI@1|root,331F4@2|Bacteria,4NWUI@976|Bacteroidetes,47T84@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_316823_2 1237149.C900_04785 1.468e-177 563.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JKI@768503|Cytophagia 976|Bacteroidetes T CheY-like receiver AAA-type ATPase and DNA-binding domains ntrX - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD2_k127_316823_12 1237149.C900_04787 2.055e-109 362.0 COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,47JPB@768503|Cytophagia 976|Bacteroidetes IQ PFAM Acyl-protein synthetase, LuxE - - - - - - - - - - - - LuxE DYD2_k127_316823_26 926556.Echvi_0199 1.503e-44 170.0 2E691@1|root,32WA1@2|Bacteria,4NT8M@976|Bacteroidetes,47R10@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_316823_1 1237149.C900_04789 0.0 1194.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia 976|Bacteroidetes C Dehydrogenase E1 component pdhB - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C DYD2_k127_316823_32 192952.MM_1310 2e-09 63.0 COG2105@1|root,arCOG03271@2157|Archaea 2157|Archaea S transferase activity, transferring acyl groups - - - - - - - - - - - - GGACT DYD2_k127_316823_5 153721.MYP_2146 4.167e-162 519.0 COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47K8G@768503|Cytophagia 976|Bacteroidetes E Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N DYD2_k127_316823_25 1121859.KB890741_gene3744 1.108e-44 166.0 COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,47QPJ@768503|Cytophagia 976|Bacteroidetes V Type I restriction enzyme R Protein - - - - - - - - - - - - HSDR_N_2 DYD2_k127_316823_10 1267211.KI669560_gene2367 3.272e-128 413.0 COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,1IP9I@117747|Sphingobacteriia 976|Bacteroidetes F Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile amn - 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - PNP_UDP_1 DYD2_k127_316823_4 1237149.C900_04795 6.172e-168 538.0 COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,47JQM@768503|Cytophagia 976|Bacteroidetes S PFAM Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 DYD2_k127_316823_21 1237149.C900_04796 6.592e-65 224.0 COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,47PP4@768503|Cytophagia 976|Bacteroidetes U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD DYD2_k127_316823_24 1124780.ANNU01000044_gene520 5.925e-61 215.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,47JBU@768503|Cytophagia 976|Bacteroidetes U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD DYD2_k127_316823_31 1189612.A33Q_2123 2.66e-15 79.0 2DDI9@1|root,2ZI7K@2|Bacteria,4P7HD@976|Bacteroidetes,47WMJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_316823_13 1237149.C900_04800 1.569e-108 357.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,47JQQ@768503|Cytophagia 976|Bacteroidetes U PFAM MotA TolQ ExbB proton channel family exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB DYD2_k127_316823_8 1237149.C900_04801 2.697e-137 445.0 COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,47KWG@768503|Cytophagia 976|Bacteroidetes EJ TIGRFAM L-asparaginases, type I ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase DYD2_k127_316823_11 1237149.C900_04802 1.495e-113 371.0 COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,47KE3@768503|Cytophagia 976|Bacteroidetes L TIGRFAM hydrolase, TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase DYD2_k127_316823_17 865937.Gilli_2466 2.678e-76 269.0 COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,1HXSS@117743|Flavobacteriia,2P5FD@244698|Gillisia 976|Bacteroidetes M Glycosyltransferase family 28 C-terminal domain - - - - - - - - - - - - Glyco_tran_28_C,Glyco_trans_1_3 DYD2_k127_316823_19 929703.KE386491_gene1790 3.928e-70 243.0 COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,47PE1@768503|Cytophagia 976|Bacteroidetes G PFAM Polysaccharide deacetylase pgdA_1 - - - - - - - - - - - Polysacc_deac_1 DYD2_k127_316823_3 1237149.C900_04805 3.405e-177 563.0 COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,47KA0@768503|Cytophagia 976|Bacteroidetes KT PFAM Stage II sporulation protein E (SpoIIE) - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - SpoIIE DYD2_k127_316823_18 1237149.C900_04806 3.728e-71 254.0 COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,47KYN@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD2_k127_316823_16 1237149.C900_04808 1.266e-83 280.0 COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,47PA6@768503|Cytophagia 976|Bacteroidetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC DYD2_k127_316823_7 1453500.AT05_02355 2.355e-150 482.0 COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia 976|Bacteroidetes M Belongs to the UDP-N-acetylglucosamine 2-epimerase family wecB - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 DYD2_k127_316823_9 1237149.C900_04811 3.431e-132 435.0 COG0438@1|root,COG0438@2|Bacteria,4NHPJ@976|Bacteroidetes 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 DYD2_k127_316823_20 1250006.JHZZ01000001_gene2283 2.298e-68 236.0 COG2227@1|root,COG2227@2|Bacteria,4NM91@976|Bacteroidetes,1HZAR@117743|Flavobacteriia,3VWYU@52959|Polaribacter 976|Bacteroidetes H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - - DYD2_k127_3184495_7 546264.NEIFLAOT_01713 1.547e-116 391.0 COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,2WGZN@28216|Betaproteobacteria,2KQUV@206351|Neisseriales 206351|Neisseriales M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glyco_transf_7C,Glycos_transf_2 DYD2_k127_3184495_6 313606.M23134_08164 2.804e-125 406.0 COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,47MB5@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_4 DYD2_k127_3184495_10 1237149.C900_01010 1.313e-104 342.0 COG1595@1|root,COG1595@2|Bacteria,4NEFR@976|Bacteroidetes,47JFG@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_3184495_27 1185876.BN8_05872 8.919e-10 62.0 2EK82@1|root,336KF@2|Bacteria,4NWXU@976|Bacteroidetes,47S8Z@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3184495_17 1237149.C900_01012 2.762e-85 286.0 COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,47M4J@768503|Cytophagia 976|Bacteroidetes F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin DYD2_k127_3184495_19 643867.Ftrac_1821 1.629e-79 269.0 COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,47JKF@768503|Cytophagia 976|Bacteroidetes H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD2_k127_3184495_1 1237149.C900_01015 1.544e-293 925.0 COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia 976|Bacteroidetes S CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 DYD2_k127_3184495_12 1124780.ANNU01000050_gene2107 4.062e-97 328.0 COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia 976|Bacteroidetes S Rhodanese Homology Domain - - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese DYD2_k127_3184495_4 1123278.KB893387_gene4352 9.883e-146 469.0 COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,47JJA@768503|Cytophagia 976|Bacteroidetes E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C DYD2_k127_3184495_9 1279009.ADICEAN_01221 6.099e-109 362.0 COG3268@1|root,COG3268@2|Bacteria,4NHDM@976|Bacteroidetes,47N4Y@768503|Cytophagia 976|Bacteroidetes S Saccharopine dehydrogenase NADP binding domain - - - - - - - - - - - - Sacchrp_dh_NADP DYD2_k127_3184495_26 880071.Fleli_0342 9.584e-25 108.0 2AMB7@1|root,31C6A@2|Bacteria,4NQ8I@976|Bacteroidetes,47Q46@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3184495_15 1237149.C900_05162 2.12e-90 304.0 COG0682@1|root,COG0682@2|Bacteria 2|Bacteria M lipoprotein biosynthetic process lgt_2 - - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD2_k127_3184495_21 1237149.C900_01018 2.409e-71 246.0 COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,47P9Z@768503|Cytophagia 976|Bacteroidetes J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF DYD2_k127_3184495_8 1237149.C900_01019 7.27e-115 373.0 COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,47JC6@768503|Cytophagia 976|Bacteroidetes F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD2_k127_3184495_23 1237149.C900_01020 1.704e-52 189.0 COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia 976|Bacteroidetes I Acetyl propionyl-CoA carboxylase alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl DYD2_k127_3184495_0 1237149.C900_01022 1.809e-298 936.0 COG4772@1|root,COG4772@2|Bacteria,4PKTE@976|Bacteroidetes,47KHE@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_3184495_18 1237149.C900_01023 2.171e-82 283.0 COG0382@1|root,COG0382@2|Bacteria,4NGNA@976|Bacteroidetes,47MCK@768503|Cytophagia 976|Bacteroidetes H PFAM UbiA prenyltransferase ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD2_k127_3184495_22 1121373.KB903636_gene811 2.137e-66 231.0 COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,47KTP@768503|Cytophagia 976|Bacteroidetes F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N DYD2_k127_3184495_16 504472.Slin_5193 7.289e-89 298.0 COG1878@1|root,COG1878@2|Bacteria,4NHMW@976|Bacteroidetes,47MGZ@768503|Cytophagia 976|Bacteroidetes S Putative cyclase - - - - - - - - - - - - Cyclase DYD2_k127_3184495_25 700598.Niako_4360 4.854e-42 158.0 COG0824@1|root,COG0824@2|Bacteria,4NS45@976|Bacteroidetes,1J14C@117747|Sphingobacteriia 976|Bacteroidetes S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 DYD2_k127_3184495_3 643867.Ftrac_0005 1.877e-204 641.0 COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,47JCV@768503|Cytophagia 976|Bacteroidetes Q Homogentisate 12-dioxygenase - - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA DYD2_k127_3184495_11 1239962.C943_00716 1.798e-98 333.0 COG1672@1|root,COG1672@2|Bacteria,4NGM3@976|Bacteroidetes,47VKT@768503|Cytophagia 976|Bacteroidetes S ATPase (AAA superfamily) - - - - - - - - - - - - ATPase_2 DYD2_k127_3184495_2 1237149.C900_01742 8.661e-238 745.0 COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,47JP7@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family ctp - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 DYD2_k127_3184495_14 1237149.C900_01741 3.311e-91 306.0 COG2846@1|root,COG2846@2|Bacteria,4NPQ7@976|Bacteroidetes,47PY2@768503|Cytophagia 976|Bacteroidetes D Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - ko:K07322 - - - - ko00000 - - - Hemerythrin DYD2_k127_3184495_24 1237149.C900_01740 1.604e-46 171.0 COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,47QCM@768503|Cytophagia 976|Bacteroidetes L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ruvX GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX DYD2_k127_3184495_20 1237149.C900_01739 3.762e-76 259.0 COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,47JIG@768503|Cytophagia 976|Bacteroidetes J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD2_k127_3184495_5 1116472.MGMO_109c00050 1.484e-138 450.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1XE5B@135618|Methylococcales 1236|Gammaproteobacteria E PFAM Aminotransferase, class I ybdL - 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_3184495_13 1124780.ANNU01000043_gene329 1.953e-94 314.0 COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,47JPF@768503|Cytophagia 976|Bacteroidetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yafV - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase DYD2_k127_3184624_4 929713.NIASO_16850 4.864e-143 458.0 COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,1IP89@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2 DYD2_k127_3184624_6 468059.AUHA01000002_gene962 6.524e-135 442.0 COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase, M28 - - - - - - - - - - - - Peptidase_M28 DYD2_k127_3184624_1 1237149.C900_05314 2.642e-223 713.0 COG4206@1|root,COG4206@2|Bacteria,4NGBJ@976|Bacteroidetes,47J8T@768503|Cytophagia 976|Bacteroidetes H TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_3184624_12 1237149.C900_05315 5.39e-61 216.0 2C9AB@1|root,2ZB91@2|Bacteria,4NKQ3@976|Bacteroidetes,47M3Q@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3184624_11 1237149.C900_05317 7.004e-71 252.0 COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia 976|Bacteroidetes T PFAM histidine kinase internal region - - - - - - - - - - - - His_kinase DYD2_k127_3184624_9 1237149.C900_05318 1.306e-86 293.0 COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes,47MTX@768503|Cytophagia 976|Bacteroidetes KT Response regulator of the LytR AlgR family - - - - - - - - - - - - LytTR,Response_reg DYD2_k127_3184624_14 1123278.KB893444_gene1666 1.297e-34 136.0 2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DoxX_2 DYD2_k127_3184624_7 643867.Ftrac_0458 1.124e-101 338.0 COG3781@1|root,COG3781@2|Bacteria,4NEB1@976|Bacteroidetes,47N85@768503|Cytophagia 976|Bacteroidetes S Bestrophin, RFP-TM, chloride channel - - - ko:K08994 - - - - ko00000,ko02000 1.A.46.2 - - Bestrophin DYD2_k127_3184624_0 1237149.C900_00597 4.236e-305 963.0 COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,47MQP@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - DYD2_k127_3184624_2 1237149.C900_00596 7.356e-221 696.0 COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD2_k127_3184624_8 313606.M23134_04189 1.622e-91 302.0 COG5405@1|root,COG5405@2|Bacteria,4NHZ8@976|Bacteroidetes,47MJS@768503|Cytophagia 976|Bacteroidetes O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome DYD2_k127_3184624_15 1237149.C900_00593 2.421e-31 124.0 COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,47JJU@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_3184624_5 1237149.C900_00593 8.517e-140 449.0 COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,47JJU@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD2_k127_3184624_13 1121904.ARBP01000010_gene2374 6.215e-44 171.0 COG5492@1|root,COG5492@2|Bacteria,4PHVH@976|Bacteroidetes,47RH7@768503|Cytophagia 976|Bacteroidetes N Electron transfer DM13 - - - - - - - - - - - - Big_2,DM13 DYD2_k127_3184624_10 1121904.ARBP01000010_gene2373 2.803e-77 269.0 2DGJB@1|root,32U7C@2|Bacteria,4NUFJ@976|Bacteroidetes,47V61@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3184624_3 1346330.M472_13750 5.53e-187 587.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,1IPZW@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD2_k127_3196233_7 1089550.ATTH01000001_gene669 4.347e-121 397.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes EU Prolyl oligopeptidase family - - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 DYD2_k127_3196233_13 641524.ADICYQ_3984 1.467e-39 149.0 COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,47R62@768503|Cytophagia 976|Bacteroidetes P PFAM Rhodanese-like domain - - - - - - - - - - - - Rhodanese DYD2_k127_3196233_14 641524.ADICYQ_3985 7.977e-28 115.0 COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,47SAY@768503|Cytophagia 976|Bacteroidetes P PFAM Rhodanese-like domain - - - - - - - - - - - - Rhodanese DYD2_k127_3196233_10 755732.Fluta_3018 6.839e-79 268.0 COG0664@1|root,COG0664@2|Bacteria,4NFIS@976|Bacteroidetes,1HXJ2@117743|Flavobacteriia,2PBNT@246874|Cryomorphaceae 976|Bacteroidetes K COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - ko:K01420 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding DYD2_k127_3196233_9 1239962.C943_02416 1.123e-82 284.0 COG1560@1|root,COG1560@2|Bacteria,4NQEF@976|Bacteroidetes 976|Bacteroidetes M Bacterial lipid A biosynthesis acyltransferase - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD2_k127_3196233_11 1237149.C900_01127 1.108e-58 209.0 COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia 976|Bacteroidetes T PFAM Phosphoglycerate mutase sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 DYD2_k127_3196233_12 1237149.C900_01125 1.338e-48 187.0 COG5571@1|root,COG5571@2|Bacteria,4NMBF@976|Bacteroidetes,47SSI@768503|Cytophagia 976|Bacteroidetes N Domain of unknown function (DUF4421) - - - - - - - - - - - - DUF4421 DYD2_k127_3196233_3 1279009.ADICEAN_02869 1.025e-213 672.0 COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,47JSG@768503|Cytophagia 976|Bacteroidetes O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small DYD2_k127_3196233_8 1237149.C900_01123 5.482e-86 296.0 COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,47KDM@768503|Cytophagia 976|Bacteroidetes I penicillin-binding protein porQ - - - - - - - - - - - PorP_SprF DYD2_k127_3196233_0 1237149.C900_01122 0.0 1228.0 COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,47M84@768503|Cytophagia 976|Bacteroidetes O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD2_k127_3196233_1 1237149.C900_01121 1.237e-266 836.0 COG2885@1|root,COG2885@2|Bacteria,4NHWF@976|Bacteroidetes,47MMG@768503|Cytophagia 976|Bacteroidetes M OmpA family - - - - - - - - - - - - OmpA,PD40 DYD2_k127_3196233_5 1237149.C900_01118 3.011e-162 523.0 COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,47JDH@768503|Cytophagia 976|Bacteroidetes M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 DYD2_k127_3196233_4 1237149.C900_01117 2.865e-191 602.0 COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia 976|Bacteroidetes I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom DYD2_k127_3196233_2 1237149.C900_01115 8.897e-255 793.0 COG0318@1|root,COG0318@2|Bacteria,4NDYR@976|Bacteroidetes,47JUW@768503|Cytophagia 976|Bacteroidetes IQ PFAM GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 DYD2_k127_3196233_6 1237149.C900_01113 1.382e-134 446.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity degQ - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 DYD2_k127_3318563_2 1237149.C900_04767 3.021e-86 288.0 COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,47JZR@768503|Cytophagia 976|Bacteroidetes F PFAM SAICAR synthetase purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt DYD2_k127_3318563_3 1237149.C900_04768 9.489e-57 200.0 COG1366@1|root,COG1366@2|Bacteria,4NTPB@976|Bacteroidetes,47R1F@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - - - - - - - - - - STAS,STAS_2 DYD2_k127_3318563_1 1237149.C900_04769 2.083e-102 342.0 COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,47KGX@768503|Cytophagia 976|Bacteroidetes S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 DYD2_k127_3318563_0 926556.Echvi_3710 5.555e-103 340.0 COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,47J8X@768503|Cytophagia 976|Bacteroidetes S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 DYD2_k127_3318563_4 1122951.ATUE01000005_gene1546 1.975e-05 47.0 COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,1RY04@1236|Gammaproteobacteria,3NIKQ@468|Moraxellaceae 1236|Gammaproteobacteria J SpoU rRNA Methylase family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind DYD2_k127_3337689_3 926549.KI421517_gene1260 9.261e-122 398.0 COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,47JNV@768503|Cytophagia 976|Bacteroidetes S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane DYD2_k127_3337689_6 761193.Runsl_3808 3.491e-89 303.0 COG2423@1|root,COG2423@2|Bacteria,4NHUM@976|Bacteroidetes,47PKC@768503|Cytophagia 976|Bacteroidetes E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD2_k127_3337689_7 1237149.C900_03317 8.432e-77 265.0 28KF8@1|root,2ZA1G@2|Bacteria,4NK7X@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3337689_13 1173023.KE650771_gene655 6.538e-42 166.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria 1117|Cyanobacteria O PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2 DYD2_k127_3337689_0 1120965.AUBV01000003_gene270 3.561e-309 956.0 COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,47JC8@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon DYD2_k127_3337689_11 1237149.C900_00723 1.684e-48 180.0 2E7DW@1|root,331WY@2|Bacteria,4NUZQ@976|Bacteroidetes,47RNZ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3337689_10 1124780.ANNU01000006_gene2814 2.12e-62 217.0 COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,47PPY@768503|Cytophagia 976|Bacteroidetes FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 DYD2_k127_3337689_15 269798.CHU_3583 2.962e-38 146.0 2DMPT@1|root,32SXV@2|Bacteria,4PKGT@976|Bacteroidetes,47R1K@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 DYD2_k127_3337689_18 1392490.JHZX01000001_gene3470 3.644e-17 83.0 2E50X@1|root,32ZUB@2|Bacteria,4NW9R@976|Bacteroidetes,1I57F@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3337689_16 153721.MYP_2711 5.217e-31 127.0 COG0782@1|root,COG0782@2|Bacteria,4NQAD@976|Bacteroidetes,47QDF@768503|Cytophagia 976|Bacteroidetes K Transcription elongation factor - - - - - - - - - - - - GreA_GreB DYD2_k127_3337689_9 929703.KE386491_gene3187 9.644e-66 230.0 COG3467@1|root,COG3467@2|Bacteria,4NHGF@976|Bacteroidetes,47N89@768503|Cytophagia 976|Bacteroidetes S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 DYD2_k127_3337689_14 665952.HMPREF1015_02599 1.9e-41 156.0 COG0454@1|root,COG0456@2|Bacteria,1UI3A@1239|Firmicutes,4ISBV@91061|Bacilli,1ZSDZ@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 DYD2_k127_3337689_4 1519464.HY22_00050 1.037e-106 355.0 COG0604@1|root,COG0604@2|Bacteria 2|Bacteria C NADPH:quinone reductase activity - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD2_k127_3337689_2 700598.Niako_5818 4.573e-136 441.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,1IP2X@117747|Sphingobacteriia 976|Bacteroidetes EH Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD2_k127_3337689_17 489825.LYNGBM3L_50810 8.088e-31 127.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB_2 DYD2_k127_3337689_12 572480.Arnit_1986 3.916e-42 158.0 COG1917@1|root,COG1917@2|Bacteria,1RGXQ@1224|Proteobacteria,42TGE@68525|delta/epsilon subdivisions,2YSAD@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - DYD2_k127_3337689_8 743722.Sph21_3791 2.146e-72 254.0 COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1ISX8@117747|Sphingobacteriia 976|Bacteroidetes EG metabolite transporter - - - - - - - - - - - - EamA DYD2_k127_3337689_1 700598.Niako_5315 2.706e-175 562.0 COG1167@1|root,COG1167@2|Bacteria,4NGKQ@976|Bacteroidetes,1IPKF@117747|Sphingobacteriia 976|Bacteroidetes K Transcriptional regulator - - - - - - - - - - - - Aminotran_1_2,GntR DYD2_k127_3337689_5 1120968.AUBX01000016_gene1600 4.919e-97 321.0 COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,47JJV@768503|Cytophagia 976|Bacteroidetes P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N DYD2_k127_3382403_1 1341181.FLJC2902T_14420 7.249e-131 422.0 COG0500@1|root,COG2226@2|Bacteria,4NIN6@976|Bacteroidetes,1IMVG@117743|Flavobacteriia,2NV8X@237|Flavobacterium 976|Bacteroidetes Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25,Ubie_methyltran DYD2_k127_3382403_6 929713.NIASO_19105 1.239e-44 167.0 COG2020@1|root,COG2020@2|Bacteria,4NJCI@976|Bacteroidetes,1IUCI@117747|Sphingobacteriia 976|Bacteroidetes O Phospholipid methyltransferase - - - - - - - - - - - - PEMT DYD2_k127_3382403_3 1454007.JAUG01000072_gene4114 4.341e-64 222.0 COG4682@1|root,COG4682@2|Bacteria,4NPA4@976|Bacteroidetes,1ISPF@117747|Sphingobacteriia 976|Bacteroidetes S yiaA/B two helix domain yiaA - - - - - - - - - - - YiaAB DYD2_k127_3382403_2 1107311.Q767_00245 4.416e-81 273.0 COG0262@1|root,COG0262@2|Bacteria,4NPJF@976|Bacteroidetes,1I4ZF@117743|Flavobacteriia,2NXEV@237|Flavobacterium 976|Bacteroidetes H RibD C-terminal domain - - - - - - - - - - - - RibD_C DYD2_k127_3382403_0 1123277.KB893172_gene573 6.463e-221 709.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NUS@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_3382403_4 1237149.C900_04701 8.316e-63 222.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD2_k127_3382403_7 156889.Mmc1_2544 5.846e-22 100.0 COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,2UFF4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sensors of blue-light using FAD - - - - - - - - - - - - BLUF DYD2_k127_3382403_5 388413.ALPR1_20263 1.016e-58 208.0 COG3832@1|root,COG3832@2|Bacteria,4NRDQ@976|Bacteroidetes,47VV2@768503|Cytophagia 976|Bacteroidetes S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD2_k127_3384591_0 1237149.C900_03306 2.365e-159 508.0 COG2876@1|root,COG2876@2|Bacteria,4NH82@976|Bacteroidetes,47KY7@768503|Cytophagia 976|Bacteroidetes E PFAM DAHP synthetase I family - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 DYD2_k127_3384591_1 1237149.C900_03305 8.993e-91 305.0 COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,47JYN@768503|Cytophagia 976|Bacteroidetes E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA DYD2_k127_3384591_2 929562.Emtol_0662 1.006e-36 140.0 COG3358@1|root,COG3358@2|Bacteria,4NFT3@976|Bacteroidetes,47NJY@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 DYD2_k127_3385835_2 1237149.C900_04446 8.233e-142 456.0 COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,47P5H@768503|Cytophagia 976|Bacteroidetes P PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like,PBP_like_2 DYD2_k127_3385835_1 1250278.JQNQ01000001_gene3577 5.323e-177 562.0 COG3746@1|root,COG3746@2|Bacteria,4NG5Z@976|Bacteroidetes,1I77C@117743|Flavobacteriia 976|Bacteroidetes P Pfam Phosphate-selective porin O and P oprP - - - - - - - - - - - Porin_O_P DYD2_k127_3385835_3 1237149.C900_04453 3.03e-140 456.0 COG3746@1|root,COG3746@2|Bacteria,4NH24@976|Bacteroidetes,47K0B@768503|Cytophagia 976|Bacteroidetes P Phosphate-selective porin O and P - - - - - - - - - - - - Porin_O_P DYD2_k127_3385835_5 1237149.C900_00023 1.926e-93 314.0 COG0688@1|root,COG0688@2|Bacteria,4NHWY@976|Bacteroidetes,47UED@768503|Cytophagia 976|Bacteroidetes I Phosphatidylserine decarboxylase psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase DYD2_k127_3385835_0 1250232.JQNJ01000001_gene3006 2.435e-228 717.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia 976|Bacteroidetes Q PFAM D-aminoacylase, C-terminal region - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 DYD2_k127_3385835_4 65393.PCC7424_3595 1.061e-104 361.0 COG2866@1|root,COG2866@2|Bacteria,1G1CQ@1117|Cyanobacteria,3KGU0@43988|Cyanothece 1117|Cyanobacteria E PFAM peptidase M14 carboxypeptidase A - - - - - - - - - - - - Peptidase_M14 DYD2_k127_3385835_6 1206725.BAFU01000029_gene2997 2.499e-57 213.0 COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria,4FXD4@85025|Nocardiaceae 201174|Actinobacteria C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N DYD2_k127_3385835_7 1123277.KB893180_gene2502 4.554e-12 67.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47MH5@768503|Cytophagia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD2_k127_3388107_1 1237149.C900_00475 5.356e-148 470.0 COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,47JX2@768503|Cytophagia 976|Bacteroidetes I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD2_k127_3388107_0 1313301.AUGC01000010_gene956 2.882e-182 574.0 COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes 976|Bacteroidetes G Aldolase fbaB - 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - DeoC DYD2_k127_3388107_4 1120965.AUBV01000008_gene2096 5.179e-46 169.0 COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,47QAS@768503|Cytophagia 976|Bacteroidetes J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 DYD2_k127_3388107_2 643867.Ftrac_1727 9.492e-108 352.0 COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,47MGG@768503|Cytophagia 976|Bacteroidetes J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT DYD2_k127_3388107_6 1237149.C900_02828 9.281e-32 130.0 COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,47QUB@768503|Cytophagia 976|Bacteroidetes J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM DYD2_k127_3388107_3 1237149.C900_02827 2.12e-62 222.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,47PR5@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 DYD2_k127_3388107_5 1237149.C900_02826 4.874e-39 148.0 COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,47JXI@768503|Cytophagia 976|Bacteroidetes C 2-oxoglutarate dehydrogenase, E1 sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr DYD2_k127_3388246_2 1237149.C900_04770 9.374e-13 68.0 COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,47J8X@768503|Cytophagia 976|Bacteroidetes S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 DYD2_k127_3388246_1 929703.KE386491_gene2088 3.612e-73 254.0 COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,47NSP@768503|Cytophagia 976|Bacteroidetes J PFAM SpoU rRNA Methylase family aviRb - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind DYD2_k127_3388246_0 1237149.C900_03344 1.431e-223 714.0 COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47K6V@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag,POTRA DYD2_k127_3397709_2 1345695.CLSA_c40780 1.124e-29 134.0 COG0793@1|root,COG0793@2|Bacteria,1UYV5@1239|Firmicutes,24B0A@186801|Clostridia,36DRS@31979|Clostridiaceae 186801|Clostridia M Peptidase, S41 - - - - - - - - - - - - Peptidase_S41 DYD2_k127_3397709_3 700598.Niako_5911 5.002e-06 50.0 COG0500@1|root,COG0500@2|Bacteria,4NZ1V@976|Bacteroidetes 976|Bacteroidetes Q methyltransferase - - - - - - - - - - - - - DYD2_k127_3397709_0 1123276.KB893290_gene5283 3.937e-77 261.0 COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes,47P6R@768503|Cytophagia 976|Bacteroidetes S Activator of Hsp90 ATPase - - - - - - - - - - - - AHSA1 DYD2_k127_3397709_1 1122621.ATZA01000003_gene1480 1.676e-49 177.0 COG0640@1|root,COG0640@2|Bacteria,4NQCU@976|Bacteroidetes,1ISSX@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Bacterial regulatory protein, arsR family - - - - - - - - - - - - HTH_20,HTH_5 DYD2_k127_3419179_5 746697.Aeqsu_1886 3.799e-10 61.0 COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1I51S@117743|Flavobacteriia 976|Bacteroidetes L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD2_k127_3419179_2 1237149.C900_03826 5.923e-37 144.0 COG3467@1|root,COG3467@2|Bacteria,4NQFR@976|Bacteroidetes,47QC8@768503|Cytophagia 976|Bacteroidetes S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 DYD2_k127_3419179_3 929556.Solca_1473 1.499e-17 87.0 2EDGF@1|root,337CN@2|Bacteria,4NXB6@976|Bacteroidetes,1IZW7@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3419179_0 1123248.KB893386_gene1911 3.939e-131 427.0 COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,1INRY@117747|Sphingobacteriia 976|Bacteroidetes T COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - - - - - - - - - - HTH_Crp_2,Response_reg,cNMP_binding DYD2_k127_3419179_1 929556.Solca_1469 2.948e-127 419.0 COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,4NG0Y@976|Bacteroidetes,1IPHZ@117747|Sphingobacteriia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_9 DYD2_k127_3419179_4 313603.FB2170_02555 2.166e-14 82.0 2AM3F@1|root,31BXJ@2|Bacteria,4NPAN@976|Bacteroidetes,1I2M5@117743|Flavobacteriia,2PHX6@252356|Maribacter 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3427395_0 945713.IALB_0592 5.478e-287 892.0 COG3808@1|root,COG3808@2|Bacteria 2|Bacteria C hydrogen-translocating pyrophosphatase activity hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA DYD2_k127_3427395_5 1120968.AUBX01000009_gene248 1.545e-70 243.0 COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,47P9H@768503|Cytophagia 976|Bacteroidetes I PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT DYD2_k127_3427395_3 153721.MYP_1180 9.162e-105 349.0 COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,47KGY@768503|Cytophagia 976|Bacteroidetes E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB - 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD2_k127_3427395_2 926549.KI421517_gene737 1.063e-161 519.0 COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,47KUN@768503|Cytophagia 976|Bacteroidetes E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N DYD2_k127_3427395_4 1237149.C900_01201 4.828e-95 316.0 COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,47P7V@768503|Cytophagia 976|Bacteroidetes J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD2_k127_3427395_1 1237149.C900_01564 5.318e-235 755.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,47JHF@768503|Cytophagia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_8 DYD2_k127_3427395_7 643867.Ftrac_0276 4.62e-06 48.0 28MS7@1|root,2ZB0M@2|Bacteria,4NHCQ@976|Bacteroidetes,47JQ9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3453495_0 1237149.C900_04535 0.0 1009.0 COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,47JUE@768503|Cytophagia 976|Bacteroidetes L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge DYD2_k127_3454909_8 1237149.C900_04426 0.0008562 43.0 COG1404@1|root,COG2133@1|root,COG2374@1|root,COG3291@1|root,COG3468@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3468@2|Bacteria,COG5492@2|Bacteria,4NJU9@976|Bacteroidetes,47NEJ@768503|Cytophagia 976|Bacteroidetes Q cell adhesion involved in biofilm formation - - - - - - - - - - - - Big_5,PKD DYD2_k127_3454909_1 1237149.C900_05312 3.04e-82 281.0 COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,47MB3@768503|Cytophagia 976|Bacteroidetes P PFAM Integral membrane protein TerC - - - - - - - - - - - - TerC DYD2_k127_3454909_4 1280390.CBQR020000100_gene2269 8.389e-57 202.0 COG2318@1|root,COG2318@2|Bacteria,1V2BI@1239|Firmicutes,4HF8B@91061|Bacilli,26XPE@186822|Paenibacillaceae 91061|Bacilli S Belongs to the metal hydrolase YfiT family yfiT - - - - - - - - - - - DinB_2 DYD2_k127_3454909_0 1237149.C900_00609 8.228e-119 391.0 COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,47JJP@768503|Cytophagia 976|Bacteroidetes S Alpha beta hydrolase - - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4 DYD2_k127_3454909_2 1124780.ANNU01000019_gene1803 2.146e-66 233.0 COG2135@1|root,COG2135@2|Bacteria,4NKPN@976|Bacteroidetes,47MR7@768503|Cytophagia 976|Bacteroidetes S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP DYD2_k127_3454909_5 153721.MYP_4730 8.893e-46 168.0 COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,47R6I@768503|Cytophagia 976|Bacteroidetes S YjbR - - - - - - - - - - - - YjbR DYD2_k127_3454909_7 1279009.ADICEAN_04149 3.821e-17 83.0 2EGC0@1|root,33A3T@2|Bacteria,4NXPB@976|Bacteroidetes,47SUC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3454909_3 643867.Ftrac_0021 8.629e-63 217.0 COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia 976|Bacteroidetes I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE DYD2_k127_347975_32 1237149.C900_01522 9.095e-105 361.0 COG3292@1|root,COG3292@2|Bacteria,4NNTX@976|Bacteroidetes,47U09@768503|Cytophagia 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - Y_Y_Y DYD2_k127_347975_39 1237149.C900_01523 1.084e-82 282.0 28IIU@1|root,2Z8JV@2|Bacteria,4NEFH@976|Bacteroidetes,47JU3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_347975_46 1237149.C900_03184 1.734e-57 204.0 COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 DYD2_k127_347975_24 1121931.AUHG01000011_gene1765 3.96e-127 419.0 COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1HY7E@117743|Flavobacteriia 976|Bacteroidetes M D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 DYD2_k127_347975_23 1237149.C900_03182 3.352e-134 439.0 COG1472@1|root,COG1472@2|Bacteria,4NET8@976|Bacteroidetes,47P5P@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 3 N terminal domain - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 DYD2_k127_347975_35 313606.M23134_03504 1.135e-98 329.0 COG3741@1|root,COG3741@2|Bacteria,4NIN9@976|Bacteroidetes,47UJG@768503|Cytophagia 976|Bacteroidetes E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase DYD2_k127_347975_16 1237149.C900_03179 9.674e-167 535.0 COG0402@1|root,COG0402@2|Bacteria,4NG64@976|Bacteroidetes,47UD9@768503|Cytophagia 976|Bacteroidetes F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD2_k127_347975_1 760192.Halhy_1605 0.0 1503.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVPS@117747|Sphingobacteriia 976|Bacteroidetes M Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_347975_0 1123278.KB893598_gene2682 0.0 1631.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_347975_9 1249997.JHZW01000002_gene946 3.29e-228 715.0 COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1HXV2@117743|Flavobacteriia,2PI0B@252356|Maribacter 976|Bacteroidetes S PA domain - - - - - - - - - - - - PA,Peptidase_M28 DYD2_k127_347975_30 1137281.D778_00414 9.129e-109 359.0 COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia 976|Bacteroidetes S Sodium bile acid symporter family - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF DYD2_k127_347975_18 1120951.AUBG01000006_gene517 8.028e-165 535.0 COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1HZPZ@117743|Flavobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 DYD2_k127_347975_21 1121904.ARBP01000009_gene4264 3.97e-158 527.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_347975_52 1237149.C900_05112 2.467e-35 138.0 COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia 976|Bacteroidetes S PFAM Membrane protein of yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 DYD2_k127_347975_15 1237149.C900_04925 9.282e-168 539.0 COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,47PIJ@768503|Cytophagia 976|Bacteroidetes L TIGRFAM exonuclease, DNA polymerase III, epsilon subunit family - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - GIY-YIG,RNase_T DYD2_k127_347975_41 1237149.C900_04913 4.283e-72 251.0 COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,47SZE@768503|Cytophagia 976|Bacteroidetes T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos DYD2_k127_347975_19 1237149.C900_04914 1.255e-164 522.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47JEN@768503|Cytophagia 976|Bacteroidetes S PFAM ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD2_k127_347975_22 1120966.AUBU01000013_gene393 2.316e-141 465.0 COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,47TMX@768503|Cytophagia 976|Bacteroidetes S Pkd domain containing protein - - - - - - - - - - - - - DYD2_k127_347975_3 1237149.C900_04916 0.0 1208.0 COG1629@1|root,COG1629@2|Bacteria,4PKRK@976|Bacteroidetes,47Y3I@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_347975_57 153721.MYP_910 1.035e-13 80.0 28NIA@1|root,2ZBJQ@2|Bacteria,4NMG9@976|Bacteroidetes,47P9M@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_347975_36 1121904.ARBP01000028_gene1645 1.416e-95 321.0 COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,47KA1@768503|Cytophagia 976|Bacteroidetes S PFAM NAD dependent epimerase dehydratase family - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase DYD2_k127_347975_28 1227739.Hsw_0138 8.248e-113 368.0 COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia 976|Bacteroidetes S Belongs to the LOG family fmt2 - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD2_k127_347975_25 1237149.C900_04921 4.807e-124 405.0 COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,47MKU@768503|Cytophagia 976|Bacteroidetes M Transglycosylase SLT domain mltD_2 - - - - - - - - - - - SLT DYD2_k127_347975_26 1189612.A33Q_3406 8.328e-114 372.0 COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes 976|Bacteroidetes F Creatinine amidohydrolase crnA - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase DYD2_k127_347975_27 1237149.C900_04572 7.847e-113 370.0 COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,47JII@768503|Cytophagia 976|Bacteroidetes F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 DYD2_k127_347975_59 446469.Sked_35900 1.446e-07 62.0 COG3595@1|root,COG3595@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2807,DUF4097 DYD2_k127_347975_40 1317122.ATO12_22060 8.338e-81 273.0 COG3738@1|root,COG3738@2|Bacteria,4NM46@976|Bacteroidetes,1I1JU@117743|Flavobacteriia,2YJD9@290174|Aquimarina 976|Bacteroidetes S Domain of unknown function (DUF1287) - - - ko:K09974 - - - - ko00000 - - - DUF1287 DYD2_k127_347975_14 760192.Halhy_2134 1.21e-168 539.0 COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1IWRU@117747|Sphingobacteriia 976|Bacteroidetes Q COGs COG1228 Imidazolonepropionase and related amidohydrolase - - - - - - - - - - - - Amidohydro_1 DYD2_k127_347975_43 1122973.KB904241_gene681 2.221e-61 215.0 COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,2FSI3@200643|Bacteroidia,22XVV@171551|Porphyromonadaceae 976|Bacteroidetes O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin DYD2_k127_347975_12 1237149.C900_03485 9.331e-183 578.0 COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JXM@768503|Cytophagia 976|Bacteroidetes I Belongs to the thiolase family - - 2.3.1.174,2.3.1.9 ko:K00626,ko:K07823 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R00829,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD2_k127_347975_38 1237149.C900_03483 1.141e-90 304.0 COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,47KUM@768503|Cytophagia 976|Bacteroidetes J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 DYD2_k127_347975_6 1237149.C900_03482 3.938e-288 894.0 COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,47JVG@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran DYD2_k127_347975_7 1237149.C900_03476 4.052e-278 865.0 COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,47JPX@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region mdlA - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran DYD2_k127_347975_13 1237149.C900_03474 1.156e-170 542.0 COG0334@1|root,COG0334@2|Bacteria,4NF3I@976|Bacteroidetes,47MHP@768503|Cytophagia 976|Bacteroidetes E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD2_k127_347975_29 1237149.C900_03473 1.357e-110 368.0 COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,47M4A@768503|Cytophagia 976|Bacteroidetes K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB DYD2_k127_347975_55 1237149.C900_03472 7.955e-30 121.0 COG4980@1|root,COG4980@2|Bacteria,4NVHP@976|Bacteroidetes,47RXK@768503|Cytophagia 976|Bacteroidetes S YtxH-like protein - - - - - - - - - - - - YtxH DYD2_k127_347975_44 1237149.C900_03471 5.962e-61 214.0 2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,47XYM@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 DYD2_k127_347975_53 153721.MYP_4133 1.501e-30 123.0 COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,47R3A@768503|Cytophagia 976|Bacteroidetes U TIGRFAM preprotein translocase, YajC subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC DYD2_k127_347975_47 1124780.ANNU01000018_gene1652 1.055e-54 204.0 COG4856@1|root,COG4856@2|Bacteria,4NK5K@976|Bacteroidetes,47K4N@768503|Cytophagia 976|Bacteroidetes S YbbR-like protein - - - - - - - - - - - - - DYD2_k127_347975_48 1124780.ANNU01000018_gene1651 7.354e-52 190.0 COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,47P6S@768503|Cytophagia 976|Bacteroidetes H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE DYD2_k127_347975_34 1237149.C900_01425 1.262e-100 338.0 COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47KNA@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 DYD2_k127_347975_2 1237149.C900_01424 0.0 1335.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K8C@768503|Cytophagia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family bepE_4 - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD2_k127_347975_37 1121904.ARBP01000005_gene4861 1.036e-91 318.0 COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP DYD2_k127_347975_31 1237149.C900_03460 1.256e-105 349.0 COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,47MUR@768503|Cytophagia 976|Bacteroidetes D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA DYD2_k127_347975_4 1237149.C900_03459 0.0 1122.0 COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,47JUB@768503|Cytophagia 976|Bacteroidetes H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C DYD2_k127_347975_45 1237149.C900_03458 1.446e-60 218.0 COG0596@1|root,COG0596@2|Bacteria,4PKUD@976|Bacteroidetes,47Y3M@768503|Cytophagia 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD2_k127_347975_33 1237149.C900_01781 2.804e-101 335.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - DYD2_k127_347975_56 1237149.C900_01784 3.952e-22 98.0 2EDEU@1|root,337B5@2|Bacteria,4NVH5@976|Bacteroidetes,47SHQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_347975_10 1237149.C900_01785 2.11e-208 655.0 COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia 976|Bacteroidetes F TIGRFAM dihydroorotase, multifunctional complex type pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 DYD2_k127_347975_20 1237149.C900_01786 1.113e-163 524.0 COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M9H@768503|Cytophagia 976|Bacteroidetes L Belongs to the DEAD box helicase family - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C DYD2_k127_347975_8 1237149.C900_03232 4.387e-257 801.0 COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,47JWD@768503|Cytophagia 976|Bacteroidetes K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind DYD2_k127_347975_11 1305737.JAFX01000001_gene2357 2.707e-187 593.0 COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,47JAB@768503|Cytophagia 976|Bacteroidetes J tRNA synthetase class II core domain (G, H, P, S and T) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b DYD2_k127_347975_5 1237149.C900_03228 0.0 1028.0 COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,47JBG@768503|Cytophagia 976|Bacteroidetes E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain pep GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N DYD2_k127_347975_49 1120965.AUBV01000003_gene376 1.548e-50 183.0 COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia 976|Bacteroidetes K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 DYD2_k127_347975_51 1237149.C900_03225 1.618e-36 140.0 2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,47RVQ@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4286) - - - - - - - - - - - - DUF4286 DYD2_k127_347975_17 1237149.C900_04486 1.732e-165 529.0 COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,47KRS@768503|Cytophagia 976|Bacteroidetes E Alanine dehydrogenase PNT, N-terminal domain - - - - - - - - - - - - AlaDh_PNT_C,AlaDh_PNT_N DYD2_k127_347975_50 1121904.ARBP01000001_gene5729 1.269e-37 148.0 COG2020@1|root,COG2020@2|Bacteria,4NTXI@976|Bacteroidetes,47RFP@768503|Cytophagia 976|Bacteroidetes O NnrU protein - - - - - - - - - - - - NnrU,PEMT DYD2_k127_347975_58 1237149.C900_04484 8.461e-13 70.0 2E4W4@1|root,32ZQB@2|Bacteria,4NUZZ@976|Bacteroidetes,47RZI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3529054_0 643867.Ftrac_1925 1.674e-120 398.0 COG1226@1|root,COG1226@2|Bacteria,4NMSS@976|Bacteroidetes,47UA5@768503|Cytophagia 976|Bacteroidetes P TrkA-N domain - - - - - - - - - - - - Ion_trans_2,TrkA_N DYD2_k127_3529054_2 925409.KI911562_gene2431 7.897e-34 134.0 COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia 976|Bacteroidetes K Transcriptional repressor, CopY family - - - - - - - - - - - - Penicillinase_R DYD2_k127_3529054_1 1121904.ARBP01000009_gene4328 9.198e-56 217.0 COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia 976|Bacteroidetes KT PFAM Peptidase M56, BlaR1 - - - - - - - - - - - - Peptidase_M56 DYD2_k127_3562157_10 1237149.C900_03437 4.232e-71 254.0 COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,47NNE@768503|Cytophagia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - DUF4175 DYD2_k127_3562157_12 1305737.JAFX01000001_gene2816 3.351e-57 201.0 29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,47R44@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3562157_14 388413.ALPR1_01190 3.576e-49 177.0 COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,47QTE@768503|Cytophagia 976|Bacteroidetes S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD DYD2_k127_3562157_11 313606.M23134_05886 2.332e-66 233.0 COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,47PYN@768503|Cytophagia 976|Bacteroidetes S TIGRFAM comF family protein comF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - Pribosyltran DYD2_k127_3562157_2 1237149.C900_00922 3.905e-226 704.0 COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,47JSB@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated lipoprotein GldJ gldJ - - - - - - - - - - - FGE-sulfatase DYD2_k127_3562157_0 1279009.ADICEAN_01936 0.0 1511.0 COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia 976|Bacteroidetes L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF DYD2_k127_3562157_8 1237149.C900_00914 1.594e-93 323.0 COG0742@1|root,COG0742@2|Bacteria,4NG6E@976|Bacteroidetes,47YDK@768503|Cytophagia 976|Bacteroidetes L Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Cons_hypoth95,PCMT DYD2_k127_3562157_15 1279009.ADICEAN_03751 5.997e-37 148.0 2CEQ4@1|root,2ZUK4@2|Bacteria,4NPFT@976|Bacteroidetes,47Q4S@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3562157_6 1519464.HY22_11525 5.479e-106 356.0 COG0477@1|root,COG2814@2|Bacteria,1FD9X@1090|Chlorobi 1090|Chlorobi EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1,MFS_2,Sugar_tr DYD2_k127_3562157_5 1150600.ADIARSV_0675 1.473e-114 380.0 COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1IQBG@117747|Sphingobacteriia 976|Bacteroidetes M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - HlyD_D23 DYD2_k127_3562157_9 743722.Sph21_0225 3.748e-91 314.0 COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IQBJ@117747|Sphingobacteriia 976|Bacteroidetes P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran,OEP DYD2_k127_3562157_1 929556.Solca_0449 0.0 1461.0 COG1538@1|root,COG3696@1|root,COG1538@2|Bacteria,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,1IQBJ@117747|Sphingobacteriia 976|Bacteroidetes P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran,OEP DYD2_k127_3562157_17 313595.P700755_000516 4.287e-08 59.0 2A3N6@1|root,30S5I@2|Bacteria,4PEAF@976|Bacteroidetes,1IC6V@117743|Flavobacteriia,4C3ZJ@83612|Psychroflexus 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3562157_4 1237149.C900_04519 1.138e-158 506.0 COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,47M4W@768503|Cytophagia 976|Bacteroidetes L SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - Radical_SAM DYD2_k127_3562157_7 1237149.C900_04631 5.508e-97 325.0 COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,47JNZ@768503|Cytophagia 976|Bacteroidetes E 1-aminocyclopropane-1-carboxylate deaminase acdS - 3.5.99.7 ko:K01505 ko00270,map00270 - R00997 RC00419 ko00000,ko00001,ko01000 - - - PALP DYD2_k127_3562157_13 1237149.C900_04630 4.027e-56 202.0 COG4843@1|root,COG4843@2|Bacteria,4NRH5@976|Bacteroidetes,47PXG@768503|Cytophagia 976|Bacteroidetes S protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179 DYD2_k127_3562157_3 1237149.C900_04629 4.361e-195 616.0 COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,47K0I@768503|Cytophagia 976|Bacteroidetes O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI DYD2_k127_3627514_4 880071.Fleli_3451 8.726e-09 57.0 COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MCZ@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD2_k127_3627514_0 1237149.C900_01609 2.362e-141 473.0 COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,47K9X@768503|Cytophagia 976|Bacteroidetes S TIGRFAM ComEC Rec2-related protein comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 DYD2_k127_3627514_1 926549.KI421517_gene2651 4.146e-137 443.0 COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,47JUG@768503|Cytophagia 976|Bacteroidetes T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH DYD2_k127_3627514_2 1237149.C900_02698 3.896e-98 326.0 COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,47PDG@768503|Cytophagia 976|Bacteroidetes S S-adenosyl-l-methionine hydroxide adenosyltransferase fjo14 - - - - - - - - - - - SAM_adeno_trans DYD2_k127_3627514_3 1305737.JAFX01000001_gene3473 4.278e-25 107.0 COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,47R4E@768503|Cytophagia 976|Bacteroidetes S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM DYD2_k127_3627514_5 746697.Aeqsu_1886 1.901e-07 54.0 COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1I51S@117743|Flavobacteriia 976|Bacteroidetes L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD2_k127_3759738_1 504472.Slin_3381 2.574e-155 499.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47MH5@768503|Cytophagia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD2_k127_3759738_0 1237149.C900_05882 0.0 1358.0 COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,47KA7@768503|Cytophagia 976|Bacteroidetes O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD2_k127_3759738_2 643867.Ftrac_1925 2.356e-07 53.0 COG1226@1|root,COG1226@2|Bacteria,4NMSS@976|Bacteroidetes,47UA5@768503|Cytophagia 976|Bacteroidetes P TrkA-N domain - - - - - - - - - - - - Ion_trans_2,TrkA_N DYD2_k127_3790955_1 1237149.C900_04077 4.238e-317 983.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,47JD4@768503|Cytophagia 976|Bacteroidetes J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 DYD2_k127_3790955_4 1237149.C900_04079 2.567e-134 441.0 COG1538@1|root,COG1538@2|Bacteria,4NU3A@976|Bacteroidetes,47P0C@768503|Cytophagia 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP DYD2_k127_3790955_5 1237149.C900_04080 9.373e-121 390.0 COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,47N33@768503|Cytophagia 976|Bacteroidetes V ABC transporter - - - - - - - - - - - - ABC_tran DYD2_k127_3790955_15 313606.M23134_02861 1.232e-31 128.0 COG2885@1|root,COG2885@2|Bacteria,4P5MU@976|Bacteroidetes 976|Bacteroidetes M OmpA family - - - - - - - - - - - - OmpA DYD2_k127_3790955_14 1237149.C900_04850 1.836e-33 135.0 COG2062@1|root,COG2062@2|Bacteria,4PMDV@976|Bacteroidetes,47Y2D@768503|Cytophagia 976|Bacteroidetes T Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 DYD2_k127_3790955_13 1237149.C900_04851 6.482e-39 150.0 2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,47R71@768503|Cytophagia 976|Bacteroidetes S Putative lumazine-binding - - - - - - - - - - - - Lumazine_bd_2 DYD2_k127_3790955_10 1237149.C900_01567 1.918e-58 218.0 COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes 976|Bacteroidetes KT COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - - - - - - - - - - SpoIIE,TPR_12 DYD2_k127_3790955_7 1237149.C900_04853 2.335e-79 269.0 COG2316@1|root,COG2316@2|Bacteria,4NU4P@976|Bacteroidetes 976|Bacteroidetes S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD DYD2_k127_3790955_9 1237149.C900_01610 4.681e-75 256.0 COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,47XYJ@768503|Cytophagia 976|Bacteroidetes O Protein of unknown function, DUF255 - - - - - - - - - - - - Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7 DYD2_k127_3790955_3 1047013.AQSP01000140_gene2509 7.964e-177 581.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_3790955_12 1144313.PMI10_03990 1.456e-50 185.0 COG0727@1|root,COG0727@2|Bacteria,4NMJ0@976|Bacteroidetes,1I1AF@117743|Flavobacteriia,2NSF3@237|Flavobacterium 976|Bacteroidetes S Putative zinc- or iron-chelating domain - - - - - - - - - - - - CxxCxxCC DYD2_k127_3790955_11 761193.Runsl_1328 7.03e-52 188.0 COG0262@1|root,COG0262@2|Bacteria,4NJIQ@976|Bacteroidetes,47PHT@768503|Cytophagia 976|Bacteroidetes H RibD C-terminal domain - - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - RibD_C DYD2_k127_3790955_2 1237149.C900_04398 1.132e-315 985.0 COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,47ME6@768503|Cytophagia 976|Bacteroidetes S PFAM Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO DYD2_k127_3790955_6 313606.M23134_01293 2.524e-109 380.0 COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia 976|Bacteroidetes M COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40 DYD2_k127_3790955_8 643867.Ftrac_1238 2.973e-75 263.0 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia 976|Bacteroidetes M TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF DYD2_k127_3790955_16 643867.Ftrac_1239 8.108e-19 104.0 COG2911@1|root,COG4932@1|root,COG5644@1|root,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes 976|Bacteroidetes M chlorophyll binding - - - - - - - - - - - - CHU_C,DUF11,SdrD_B DYD2_k127_3790955_0 1336803.PHEL49_2496 0.0 1077.0 COG1361@1|root,COG2373@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein inlJ - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - CHU_C,DUF11,DUF5011,FctA,Gram_pos_anchor,MucBP,VWA_2 DYD2_k127_3807382_13 1237149.C900_00391 1.318e-49 183.0 COG3595@1|root,COG3595@2|Bacteria,4NJBA@976|Bacteroidetes,47MRP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3807382_11 1237149.C900_00390 7.272e-91 306.0 COG3595@1|root,COG3595@2|Bacteria,4NGRU@976|Bacteroidetes,47MSM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4097 DYD2_k127_3807382_15 1347342.BN863_5230 3.065e-31 137.0 COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,1HZ1M@117743|Flavobacteriia 976|Bacteroidetes M PDZ domain (Also known as DHR or GLGF) - - - - - - - - - - - - Asp_protease_2,PDZ,PDZ_2 DYD2_k127_3807382_6 1237149.C900_03504 1.904e-117 384.0 COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,47MVC@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18 DYD2_k127_3807382_16 1408813.AYMG01000017_gene5614 0.0001056 49.0 2ED1U@1|root,336YR@2|Bacteria,4NUXY@976|Bacteroidetes,1IYKA@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3807382_2 1237149.C900_04399 2.743e-175 558.0 COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,47KTS@768503|Cytophagia 976|Bacteroidetes O Zn-dependent protease with chaperone function - - 3.4.24.84 ko:K03799,ko:K06013 ko00900,ko01130,map00900,map01130 M00743 R09845 RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N DYD2_k127_3807382_12 1280946.HY29_01020 2.956e-59 218.0 COG3118@1|root,COG3118@2|Bacteria,1R12J@1224|Proteobacteria,2TYWR@28211|Alphaproteobacteria,440VM@69657|Hyphomonadaceae 28211|Alphaproteobacteria O belongs to the thioredoxin family - - - - - - - - - - - - - DYD2_k127_3807382_7 1278307.KB906994_gene2879 4.498e-111 364.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,2QIRI@267894|Psychromonadaceae 1236|Gammaproteobacteria M Conserved TM helix mscS - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix DYD2_k127_3807382_0 485918.Cpin_6550 8.113e-203 639.0 COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1INUE@117747|Sphingobacteriia 976|Bacteroidetes E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Lyase_1 DYD2_k127_3807382_3 391596.PBAL39_12082 3.571e-147 473.0 COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,1IQBT@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Peptidase family M20 M25 M40 argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD2_k127_3807382_8 1123248.KB893386_gene1816 9.076e-103 340.0 COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,1IPBE@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD2_k127_3807382_4 485918.Cpin_6553 7.823e-146 467.0 COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1IQ2H@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the ATCase OTCase family argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 ko:K09065,ko:K13043 ko00220,ko01100,ko01230,map00220,map01100,map01230 M00845 R07245,R08937 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD2_k127_3807382_9 1121930.AQXG01000011_gene1767 1.665e-100 334.0 COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1IR2E@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer DYD2_k127_3807382_5 485918.Cpin_6555 1.345e-131 426.0 COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,1IPHE@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD2_k127_3807382_1 485918.Cpin_6556 1.938e-193 610.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1INXV@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth DYD2_k127_3807382_10 485918.Cpin_6557 4.547e-94 314.0 COG1246@1|root,COG1246@2|Bacteria,4NGXY@976|Bacteroidetes 976|Bacteroidetes E Acetyltransferase - - - - - - - - - - - - Acetyltransf_1 DYD2_k127_3807382_14 1237149.C900_00839 1.415e-43 164.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_382746_7 929703.KE386491_gene540 9.655e-187 606.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47N2K@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD2_k127_382746_27 504472.Slin_5426 1.974e-68 235.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47XN3@768503|Cytophagia 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 DYD2_k127_382746_30 1237149.C900_05727 4.429e-49 184.0 28P2C@1|root,2ZBYG@2|Bacteria,4NMEQ@976|Bacteroidetes,47PKX@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_382746_29 641524.ADICYQ_1978 1.586e-56 201.0 COG1764@1|root,COG1764@2|Bacteria,4P9T2@976|Bacteroidetes,47S0N@768503|Cytophagia 976|Bacteroidetes O OsmC-like protein - - - - - - - - - - - - OsmC DYD2_k127_382746_33 344747.PM8797T_15326 3.12e-37 151.0 arCOG08211@1|root,2ZBM3@2|Bacteria,2IZ2K@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - DYD2_k127_382746_40 1237149.C900_00884 1.634e-18 94.0 29Z9Q@1|root,30M7X@2|Bacteria,4NWQ3@976|Bacteroidetes,47WAG@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3592) - - - - - - - - - - - - DUF3592 DYD2_k127_382746_3 509635.N824_28650 8.049e-278 869.0 COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,1IPA6@117747|Sphingobacteriia 976|Bacteroidetes O peptidase M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N DYD2_k127_382746_32 1237149.C900_04212 3.161e-44 172.0 COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes 976|Bacteroidetes T universal stress protein - - - - - - - - - - - - Usp DYD2_k127_382746_20 700598.Niako_3670 1.499e-98 332.0 COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1IYQQ@117747|Sphingobacteriia 976|Bacteroidetes S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM DYD2_k127_382746_15 700598.Niako_3669 1.902e-114 381.0 COG1502@1|root,COG1502@2|Bacteria,4P0CZ@976|Bacteroidetes,1J0D9@117747|Sphingobacteriia 976|Bacteroidetes I Phospholipase D. Active site motifs. - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD2_k127_382746_1 643867.Ftrac_0533 8.04e-305 940.0 COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,47JG7@768503|Cytophagia 976|Bacteroidetes S COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn DYD2_k127_382746_37 1166018.FAES_3482 1.968e-21 101.0 COG0810@1|root,COG0810@2|Bacteria,4NJG7@976|Bacteroidetes,47JHH@768503|Cytophagia 976|Bacteroidetes M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD2_k127_382746_34 313595.P700755_000875 9.33e-35 141.0 2AXAT@1|root,31P9W@2|Bacteria,4PKR4@976|Bacteroidetes,1IJCX@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4303 DYD2_k127_382746_14 929703.KE386491_gene3153 4.835e-127 415.0 COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47NRC@768503|Cytophagia 976|Bacteroidetes I fatty acid desaturase - - 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase DYD2_k127_382746_17 1254432.SCE1572_01320 4.765e-108 359.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42QBD@68525|delta/epsilon subdivisions,2WM4P@28221|Deltaproteobacteria,2YZSV@29|Myxococcales 28221|Deltaproteobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 DYD2_k127_382746_36 616991.JPOO01000001_gene3958 3.147e-28 118.0 arCOG10456@1|root,2ZA6T@2|Bacteria,4NGZ2@976|Bacteroidetes,1HXIA@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_382746_22 700598.Niako_4642 6.648e-81 274.0 arCOG08955@1|root,2ZN6H@2|Bacteria,4NR64@976|Bacteroidetes,1IXYG@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_382746_23 1150600.ADIARSV_2575 2.627e-76 259.0 COG1917@1|root,COG1917@2|Bacteria,4PNAF@976|Bacteroidetes,1ITCG@117747|Sphingobacteriia 976|Bacteroidetes S Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_382746_11 1123278.KB893433_gene638 1.652e-149 477.0 COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,47JGG@768503|Cytophagia 976|Bacteroidetes Q dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD2_k127_382746_43 1166018.FAES_2758 4.056e-08 64.0 COG3279@1|root,COG3279@2|Bacteria,4NJ3A@976|Bacteroidetes,47P1F@768503|Cytophagia 976|Bacteroidetes KT LytTr DNA-binding domain - - - - - - - - - - - - LytTR DYD2_k127_382746_39 385682.AFSL01000025_gene2079 6.477e-20 98.0 COG1266@1|root,COG1266@2|Bacteria,4NGBZ@976|Bacteroidetes 976|Bacteroidetes S CAAX protease self-immunity - - - - - - - - - - - - Abi DYD2_k127_382746_26 472175.EL18_01162 4.582e-71 252.0 COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2TUAH@28211|Alphaproteobacteria,43JDU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Eukaryotic DNA topoisomerase I, catalytic core MA20_25110 - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_I DYD2_k127_382746_19 1379698.RBG1_1C00001G0467 3.363e-103 344.0 COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria 2|Bacteria P Integral membrane protein TerC family terC - - ko:K05794 - - - - ko00000 - - - TerC DYD2_k127_382746_25 1249997.JHZW01000003_gene2824 5.977e-73 253.0 COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia,2PG9T@252356|Maribacter 976|Bacteroidetes S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin DYD2_k127_382746_38 571166.KI421509_gene4229 1.407e-20 92.0 COG3360@1|root,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Dodecin - - - ko:K09165 - - - - ko00000 - - - Dodecin DYD2_k127_382746_31 313603.FB2170_13021 5.967e-49 179.0 COG0454@1|root,COG0456@2|Bacteria,4NQV0@976|Bacteroidetes,1I1XX@117743|Flavobacteriia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 DYD2_k127_382746_35 381764.Fnod_0083 2.565e-31 134.0 COG2819@1|root,COG2819@2|Bacteria,2GE2J@200918|Thermotogae 200918|Thermotogae S Putative esterase - - - - - - - - - - - - Esterase DYD2_k127_382746_0 1121875.KB907553_gene120 0.0 1463.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia 976|Bacteroidetes G BNR Asp-box repeat - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_382746_8 1392498.JQLH01000001_gene2593 4.863e-175 561.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia,2PHHE@252356|Maribacter 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD2_k127_382746_21 1122176.KB903554_gene3968 3.241e-82 278.0 COG0637@1|root,COG0637@2|Bacteria,4NEEH@976|Bacteroidetes,1IRVG@117747|Sphingobacteriia 976|Bacteroidetes S subfamily IA, variant 3 with third motif having DD or ED pgmB - - - - - - - - - - - HAD_2 DYD2_k127_382746_44 1120965.AUBV01000004_gene783 8.465e-07 58.0 COG3047@1|root,COG3047@2|Bacteria,4PPHC@976|Bacteroidetes,47YN3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - OMP_b-brl DYD2_k127_382746_24 1121890.AUDO01000006_gene1276 3.315e-75 258.0 COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1HX2T@117743|Flavobacteriia,2NTWM@237|Flavobacterium 976|Bacteroidetes S Conserved hypothetical protein (DUF2461) - - - - - - - - - - - - DUF2461 DYD2_k127_382746_16 1237149.C900_04562 2.376e-109 362.0 COG3250@1|root,COG3250@2|Bacteria,4NN59@976|Bacteroidetes 976|Bacteroidetes G beta-galactosidase activity - - - - - - - - - - - - BetaGal_dom4_5 DYD2_k127_382746_18 1237149.C900_04559 1.926e-105 346.0 COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,47PDQ@768503|Cytophagia 976|Bacteroidetes T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C DYD2_k127_382746_12 1237149.C900_04558 1.587e-145 477.0 COG0642@1|root,COG2205@2|Bacteria,4NUBB@976|Bacteroidetes 976|Bacteroidetes T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA DYD2_k127_382746_5 1121101.HMPREF1532_01735 4.327e-230 762.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NG0B@976|Bacteroidetes,2FM88@200643|Bacteroidia,4AMAH@815|Bacteroidaceae 976|Bacteroidetes T Response regulator receiver domain protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y DYD2_k127_382746_9 657309.BXY_23240 6.132e-166 528.0 COG2152@1|root,COG2152@2|Bacteria,4NGI7@976|Bacteroidetes,2FMV9@200643|Bacteroidia,4APG4@815|Bacteroidaceae 976|Bacteroidetes G Pfam:DUF377 - - 2.4.1.339,2.4.1.340 ko:K20885 - - R11397,R11398 RC00049,RC02748 ko00000,ko01000 - GH130 - Glyco_hydro_130 DYD2_k127_382746_13 1408473.JHXO01000011_gene3130 2.034e-145 472.0 COG0477@1|root,COG0477@2|Bacteria,4NGD7@976|Bacteroidetes,2G15G@200643|Bacteroidia 976|Bacteroidetes EGP Major facilitator Superfamily - - - ko:K08222 - - - - ko00000,ko02000 2.A.1.33 - - MFS_1 DYD2_k127_382746_6 449673.BACSTE_02585 1.006e-223 709.0 2DBD9@1|root,2Z8J6@2|Bacteria,4NHNA@976|Bacteroidetes,2FP0C@200643|Bacteroidia,4APJH@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_382746_2 1166018.FAES_1548 3.913e-299 949.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47Y6I@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_382746_10 1166018.FAES_1549 2.55e-158 514.0 COG0702@1|root,COG0702@2|Bacteria,4PKHQ@976|Bacteroidetes,47XXB@768503|Cytophagia 976|Bacteroidetes GM SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB DYD2_k127_382746_28 1166018.FAES_1550 3.668e-63 230.0 COG4733@1|root,COG4733@2|Bacteria,4NPYJ@976|Bacteroidetes 976|Bacteroidetes S Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 DYD2_k127_382746_4 1349822.NSB1T_01170 6.803e-274 876.0 COG4733@1|root,COG4733@2|Bacteria,4PP23@976|Bacteroidetes 976|Bacteroidetes S Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 DYD2_k127_382746_42 649349.Lbys_2840 1.72e-09 60.0 COG0662@1|root,COG0662@2|Bacteria,4NNWT@976|Bacteroidetes,47Q0Y@768503|Cytophagia 976|Bacteroidetes G PFAM Mannose-6-phosphate isomerase - - - - - - - - - - - - MannoseP_isomer DYD2_k127_3862802_4 1087481.AGFX01000018_gene1675 3.083e-54 193.0 COG0028@1|root,COG4032@1|root,COG0028@2|Bacteria,COG4032@2|Bacteria,1TSJZ@1239|Firmicutes,4HDPN@91061|Bacilli,26SAQ@186822|Paenibacillaceae 91061|Bacilli EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 4.1.1.82 ko:K09459 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R04053 RC00506 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_N DYD2_k127_3862802_2 1295642.H839_06474 9.072e-64 227.0 COG0075@1|root,COG1213@1|root,COG0075@2|Bacteria,COG1213@2|Bacteria,1TPS0@1239|Firmicutes,4IETS@91061|Bacilli,1WHEJ@129337|Geobacillus 91061|Bacilli EM Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW - - - - - - - - - - - Aminotran_5,NTP_transf_3 DYD2_k127_3862802_1 1237149.C900_02661 7.566e-198 634.0 COG1368@1|root,COG1368@2|Bacteria,4NFI9@976|Bacteroidetes,47K4G@768503|Cytophagia 976|Bacteroidetes M COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily ltaS2 - - - - - - - - - - - Sulfatase DYD2_k127_3862802_5 497964.CfE428DRAFT_5334 5.146e-21 98.0 COG3216@1|root,COG3216@2|Bacteria 2|Bacteria M Uncharacterized protein conserved in bacteria (DUF2062) - - - ko:K09928 - - - - ko00000 - - - DUF2062 DYD2_k127_3862802_3 1124780.ANNU01000020_gene3294 2.957e-59 214.0 COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,47PRX@768503|Cytophagia 976|Bacteroidetes S PFAM DUF218 domain - - - - - - - - - - - - DUF218 DYD2_k127_3862802_0 1237149.C900_05256 1.808e-318 989.0 COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia 976|Bacteroidetes V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane,ABC_tran,TerB DYD2_k127_3894553_6 1237149.C900_05890 4.289e-71 254.0 COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes,47MS8@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD DYD2_k127_3894553_11 1237149.C900_05891 1.182e-49 185.0 COG3103@1|root,COG3103@2|Bacteria,4NIH7@976|Bacteroidetes,47P4Z@768503|Cytophagia 976|Bacteroidetes T Sh3 type 3 domain protein - - - - - - - - - - - - SH3_3,SH3_4 DYD2_k127_3894553_20 485918.Cpin_3000 5.753e-07 52.0 COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,1IT98@117747|Sphingobacteriia 976|Bacteroidetes L resolvase domain - - - - - - - - - - - - Recombinase,Resolvase DYD2_k127_3894553_2 1086011.HJ01_02091 3.8e-96 325.0 COG0628@1|root,COG0628@2|Bacteria,4NHP4@976|Bacteroidetes,1HXG6@117743|Flavobacteriia,2NVB7@237|Flavobacterium 976|Bacteroidetes S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD2_k127_3894553_14 865937.Gilli_3289 5.352e-40 151.0 COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia,2P6Z2@244698|Gillisia 976|Bacteroidetes S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 DYD2_k127_3894553_15 765869.BDW_02625 8.605e-38 147.0 COG2259@1|root,COG2259@2|Bacteria,1NCQT@1224|Proteobacteria,42WUM@68525|delta/epsilon subdivisions,2MTDS@213481|Bdellovibrionales,2WT9R@28221|Deltaproteobacteria 213481|Bdellovibrionales S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX DYD2_k127_3894553_0 1237149.C900_05714 8.736e-192 613.0 COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,47MAI@768503|Cytophagia 976|Bacteroidetes O Peptidase S8 and S53 subtilisin kexin sedolisin wprA - - - - - - - - - - - Peptidase_S8 DYD2_k127_3894553_16 694427.Palpr_2287 4.427e-25 108.0 COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes 976|Bacteroidetes L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD2_k127_3894553_18 1237149.C900_05473 6.154e-18 89.0 2EPSB@1|root,33HCU@2|Bacteria,4NYPB@976|Bacteroidetes,47SU9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3894553_12 1237149.C900_04229 1.544e-49 179.0 COG1959@1|root,COG1959@2|Bacteria,4NNN2@976|Bacteroidetes,47P8M@768503|Cytophagia 976|Bacteroidetes K TIGRFAM Transcriptional regulator, Rrf2 cymR - - - - - - - - - - - Rrf2 DYD2_k127_3894553_1 1288963.ADIS_1340 6.381e-121 397.0 COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,47KU9@768503|Cytophagia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - 1.8.3.7 ko:K13444 ko04142,map04142 - - - ko00000,ko00001,ko01000 - - - FGE-sulfatase DYD2_k127_3894553_8 177437.HRM2_23520 5.57e-65 233.0 COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,42QP3@68525|delta/epsilon subdivisions,2WMTD@28221|Deltaproteobacteria,2MN7C@213118|Desulfobacterales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_3894553_10 1237149.C900_05477 1.273e-54 197.0 COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_3894553_17 1124780.ANNU01000006_gene2857 8.656e-20 98.0 COG1413@1|root,COG1413@2|Bacteria,4NIBA@976|Bacteroidetes,47M5K@768503|Cytophagia 976|Bacteroidetes C HEAT repeats - - - - - - - - - - - - HEAT_2,zf-HC2 DYD2_k127_3894553_5 1233951.IO90_14015 8.019e-79 270.0 COG3595@1|root,COG3595@2|Bacteria,4NKSN@976|Bacteroidetes,1I2JR@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4097 DYD2_k127_3894553_9 1218108.KB908302_gene2742 2.503e-63 226.0 COG3595@1|root,COG3595@2|Bacteria,4NKSN@976|Bacteroidetes,1I2JR@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4097 DYD2_k127_3894553_7 1121285.AUFK01000001_gene2008 8.407e-71 247.0 COG3595@1|root,COG3595@2|Bacteria,4NT4J@976|Bacteroidetes,1I4N5@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3894553_13 700598.Niako_5254 2.876e-46 173.0 COG2940@1|root,COG2940@2|Bacteria,4NQ3D@976|Bacteroidetes 976|Bacteroidetes S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - ko:K07117 - - - - ko00000 - - - SET DYD2_k127_3894553_19 471854.Dfer_5208 1.078e-08 63.0 2EG8H@1|root,335T3@2|Bacteria,4NW8Q@976|Bacteroidetes,47S7Q@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3894553_3 743722.Sph21_3222 1.679e-94 318.0 COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,1IQJU@117747|Sphingobacteriia 976|Bacteroidetes E Prephenate dehydratase pheA - 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - - PDT DYD2_k127_3894553_4 643867.Ftrac_0292 8.941e-93 310.0 COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,47KXG@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II dapL - 2.6.1.83 ko:K10206,ko:K14261 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_392870_3 1237149.C900_04955 2.829e-33 130.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47K6G@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_392870_1 1237149.C900_05634 2.521e-62 220.0 COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,47UM2@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD2_k127_392870_2 1185876.BN8_04246 1.288e-60 213.0 COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia 976|Bacteroidetes O Peptidyl-prolyl cis-trans isomerase slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C DYD2_k127_392870_0 1237149.C900_05632 0.0 1157.0 COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia 976|Bacteroidetes S Peptidase family C25 - - - - - - - - - - - - CARDB,FlgD_ig,ILEI,Peptidase_C25 DYD2_k127_3949366_23 1123234.AUKI01000023_gene1935 1.076e-59 212.0 COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,1I0VV@117743|Flavobacteriia 976|Bacteroidetes Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 DYD2_k127_3949366_14 313606.M23134_00570 1.197e-98 328.0 COG0010@1|root,COG0010@2|Bacteria,4NHDP@976|Bacteroidetes,47UNV@768503|Cytophagia 976|Bacteroidetes E Arginase family - - - - - - - - - - - - Arginase DYD2_k127_3949366_5 1121904.ARBP01000006_gene3720 1.343e-186 593.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47MZ0@768503|Cytophagia 976|Bacteroidetes E Pyridoxal-dependent decarboxylase conserved domain - - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC DYD2_k127_3949366_16 1121904.ARBP01000009_gene4152 1.851e-80 279.0 2DN4I@1|root,32VGS@2|Bacteria,4NNY4@976|Bacteroidetes,47PHY@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 DYD2_k127_3949366_0 1121904.ARBP01000009_gene4153 1.8e-322 1004.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47JN3@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_3949366_7 1237149.C900_05601 5.433e-143 461.0 COG1215@1|root,COG1215@2|Bacteria,4PKF3@976|Bacteroidetes,47XY0@768503|Cytophagia 976|Bacteroidetes M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD2_k127_3949366_35 641524.ADICYQ_1943 4.513e-30 126.0 29S8X@1|root,30DDE@2|Bacteria,4NRBB@976|Bacteroidetes,47RMJ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4199) - - - - - - - - - - - - DUF4199 DYD2_k127_3949366_6 1237149.C900_05598 1.667e-153 495.0 COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,47KKP@768503|Cytophagia 976|Bacteroidetes F TIGRFAM dihydroorotase, multifunctional complex type pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 DYD2_k127_3949366_3 1237149.C900_05597 4.587e-191 617.0 COG1361@1|root,COG1361@2|Bacteria,4PKPA@976|Bacteroidetes 976|Bacteroidetes M Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA,CARDB DYD2_k127_3949366_26 1237149.C900_05594 7.632e-46 168.0 COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47RWZ@768503|Cytophagia 976|Bacteroidetes L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB DYD2_k127_3949366_29 714943.Mucpa_4289 3.252e-41 154.0 COG4068@1|root,COG4068@2|Bacteria,4NQ3Z@976|Bacteroidetes,1ITN4@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF2116 DYD2_k127_3949366_15 929703.KE386491_gene1082 1.215e-86 293.0 COG1028@1|root,COG1028@2|Bacteria,4NKY7@976|Bacteroidetes,47MF4@768503|Cytophagia 976|Bacteroidetes IQ KR domain - - 1.1.1.206 ko:K08081 ko00960,ko01100,ko01110,map00960,map01100,map01110 - R02832 RC00144 ko00000,ko00001,ko01000 - - - adh_short_C2 DYD2_k127_3949366_17 1250232.JQNJ01000001_gene172 2.119e-79 270.0 COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes,1HXI5@117743|Flavobacteriia 976|Bacteroidetes P Cation efflux family - - - - - - - - - - - - Cation_efflux DYD2_k127_3949366_18 1237149.C900_02649 1.831e-68 242.0 COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,47WZW@768503|Cytophagia 976|Bacteroidetes S Excinuclease ABC subunit B - - - - - - - - - - - - ABC2_membrane_2,ABC2_membrane_4 DYD2_k127_3949366_9 1237149.C900_02648 4.142e-114 374.0 COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,47Q1V@768503|Cytophagia 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_3949366_25 1237149.C900_02644 5.462e-55 198.0 2CC1H@1|root,33P9C@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 DYD2_k127_3949366_34 1237149.C900_02643 2.159e-30 126.0 2BVQD@1|root,332WQ@2|Bacteria,4NXE1@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3949366_24 1237149.C900_02642 2.094e-58 207.0 COG1595@1|root,COG1595@2|Bacteria,4NSED@976|Bacteroidetes,47Q3K@768503|Cytophagia 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_3949366_38 1356852.N008_09145 0.0001924 46.0 2APBA@1|root,31EDH@2|Bacteria,4NSFA@976|Bacteroidetes,47SNA@768503|Cytophagia 976|Bacteroidetes S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 DYD2_k127_3949366_4 1237149.C900_05585 1.564e-190 611.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2 DYD2_k127_3949366_31 714943.Mucpa_2218 1.06e-33 136.0 29AZZ@1|root,2ZXYX@2|Bacteria,4NP6M@976|Bacteroidetes,1ITA8@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3949366_12 269798.CHU_1800 3.145e-104 347.0 2DBXV@1|root,2ZBR7@2|Bacteria,4NNEK@976|Bacteroidetes,47U2F@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3949366_20 700598.Niako_5650 2.654e-64 222.0 COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia 976|Bacteroidetes J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase DYD2_k127_3949366_19 1237149.C900_05756 1.542e-67 235.0 COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,47PTQ@768503|Cytophagia 976|Bacteroidetes GM epimerase - - - - - - - - - - - - Epimerase,NAD_binding_10 DYD2_k127_3949366_36 1237149.C900_05757 4.181e-21 98.0 COG3339@1|root,COG3339@2|Bacteria,4NVFR@976|Bacteroidetes,47RD8@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 DYD2_k127_3949366_21 1237149.C900_05758 1.233e-61 216.0 28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,47M02@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3949366_30 1124780.ANNU01000030_gene1165 1.048e-34 136.0 COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes,47R1C@768503|Cytophagia 976|Bacteroidetes S Belongs to the HesB IscA family iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn DYD2_k127_3949366_33 1237149.C900_00241 5.31e-32 128.0 COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,47QM5@768503|Cytophagia 976|Bacteroidetes H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB DYD2_k127_3949366_22 1237149.C900_00242 6.629e-61 217.0 COG3599@1|root,COG3599@2|Bacteria,4NQDF@976|Bacteroidetes,47QRC@768503|Cytophagia 976|Bacteroidetes D TIGRFAM DivIVA domain divIVA - - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA DYD2_k127_3949366_11 1237149.C900_00243 1.217e-110 365.0 COG2319@1|root,COG2319@2|Bacteria,4NH20@976|Bacteroidetes,47JUN@768503|Cytophagia 976|Bacteroidetes S PFAM WD domain, G-beta repeat - - - - - - - - - - - - WD40 DYD2_k127_3949366_27 1124780.ANNU01000030_gene1161 4.897e-45 170.0 COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,47RPQ@768503|Cytophagia 976|Bacteroidetes H Belongs to the P-Pant transferase superfamily sfp - - - - - - - - - - - ACPS DYD2_k127_3949366_28 1237149.C900_00245 1.185e-42 164.0 COG0526@1|root,COG0526@2|Bacteria,4NSUU@976|Bacteroidetes,47R9W@768503|Cytophagia 976|Bacteroidetes CO AhpC/TSA family - - - - - - - - - - - - AhpC-TSA,Redoxin DYD2_k127_3949366_8 1237149.C900_01093 1.347e-125 408.0 COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,47JJ3@768503|Cytophagia 976|Bacteroidetes S Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core2 DYD2_k127_3949366_1 1237149.C900_01092 2.497e-310 955.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47JYJ@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) accD5 - - - - - - - - - - - Carboxyl_trans DYD2_k127_3949366_13 1237149.C900_01090 2.035e-103 345.0 COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,47MMF@768503|Cytophagia 976|Bacteroidetes Q Mammalian cell entry related domain protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD2_k127_3949366_10 1237149.C900_01089 7.158e-111 365.0 COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,47M2P@768503|Cytophagia 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 DYD2_k127_3949366_2 1237149.C900_01088 2.632e-268 852.0 COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,47JIS@768503|Cytophagia 976|Bacteroidetes M Organic solvent tolerance protein OstA - - - - - - - - - - - - - DYD2_k127_3969507_19 1203190.CAJP01000033_gene1177 1.229e-06 52.0 COG1826@1|root,COG1826@2|Bacteria,2GQQX@201174|Actinobacteria,22P58@1653|Corynebacteriaceae 201174|Actinobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0008150,GO:0040007 - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD2_k127_3969507_10 1237149.C900_02563 1.457e-104 347.0 COG4978@1|root,COG4978@2|Bacteria,4NHII@976|Bacteroidetes 976|Bacteroidetes KT PFAM Bacterial transcription activator, effector binding domain - - - - - - - - - - - - GyrI-like DYD2_k127_3969507_0 1237149.C900_02562 0.0 1034.0 COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,47MTU@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 65, N-terminal domain kojP - - - - - - - - - - - Glyco_hydro_65N,Glyco_hydro_65m DYD2_k127_3969507_4 1237149.C900_02560 4.184e-188 597.0 COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47JAV@768503|Cytophagia 976|Bacteroidetes I PAP2 superfamily - - - - - - - - - - - - PAP2 DYD2_k127_3969507_18 1121481.AUAS01000008_gene3072 1.354e-14 82.0 2E4RS@1|root,32ZKA@2|Bacteria,4NVN5@976|Bacteroidetes,47RDU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_3969507_1 1286632.P278_14210 4.89e-249 797.0 COG4206@1|root,COG4206@2|Bacteria,4PM6D@976|Bacteroidetes,1IKG3@117743|Flavobacteriia 976|Bacteroidetes H TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_3969507_14 471854.Dfer_4403 1.346e-40 165.0 28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,47NIB@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 DYD2_k127_3969507_17 1086011.HJ01_01529 1.721e-19 102.0 COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia,2NSPN@237|Flavobacterium 976|Bacteroidetes S Large extracellular alpha-helical protein - - - - - - - - - - - - A2M_N DYD2_k127_3969507_16 746697.Aeqsu_2964 7.668e-31 132.0 COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia 976|Bacteroidetes S Large extracellular alpha-helical protein - - - - - - - - - - - - A2M_N DYD2_k127_3969507_3 1198452.Jab_2c33050 9.799e-204 642.0 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2VNA1@28216|Betaproteobacteria,476QD@75682|Oxalobacteraceae 28216|Betaproteobacteria G Major Facilitator Superfamily - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 DYD2_k127_3969507_7 643867.Ftrac_0487 3.276e-124 404.0 COG1940@1|root,COG1940@2|Bacteria,4NGC1@976|Bacteroidetes,47KEB@768503|Cytophagia 976|Bacteroidetes GK PFAM ROK family - - - - - - - - - - - - ROK DYD2_k127_3969507_8 313596.RB2501_14094 2.498e-113 374.0 COG0524@1|root,COG0524@2|Bacteria,4NJIK@976|Bacteroidetes,1I00V@117743|Flavobacteriia 976|Bacteroidetes G pfkB family carbohydrate kinase - - 2.7.1.20 ko:K00856 ko00230,ko01100,map00230,map01100 - R00185 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB DYD2_k127_3969507_2 688270.Celal_1743 1.305e-224 700.0 COG0477@1|root,COG2814@2|Bacteria,4PKJD@976|Bacteroidetes,1IJAV@117743|Flavobacteriia 976|Bacteroidetes EGP Nucleoside H symporter - - - - - - - - - - - - Nuc_H_symport DYD2_k127_3969507_6 1123073.KB899241_gene2381 3.233e-166 530.0 COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,1RMKA@1236|Gammaproteobacteria,1X60T@135614|Xanthomonadales 135614|Xanthomonadales S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_3969507_5 485918.Cpin_7279 8.929e-183 576.0 COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1IQDJ@117747|Sphingobacteriia 976|Bacteroidetes G AP endonuclease - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N DYD2_k127_3969507_11 1122176.KB903540_gene121 7.922e-88 297.0 COG2133@1|root,COG4654@1|root,COG2133@2|Bacteria,COG4654@2|Bacteria,4NEMM@976|Bacteroidetes,1J0A5@117747|Sphingobacteriia 976|Bacteroidetes CG PA14 - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C,DUF1080,PA14 DYD2_k127_3969507_12 1123276.KB893250_gene336 1.16e-75 264.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,47NJ6@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 DYD2_k127_3969507_9 1123248.KB893325_gene1170 2.896e-105 349.0 COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,1INUU@117747|Sphingobacteriia 976|Bacteroidetes G Hydroxypyruvate isomerase - - 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 DYD2_k127_3969507_13 1123073.KB899241_gene3088 1.623e-42 162.0 2DPQD@1|root,332Z4@2|Bacteria,1R3FS@1224|Proteobacteria,1T67D@1236|Gammaproteobacteria,1X7FX@135614|Xanthomonadales 1224|Proteobacteria S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 DYD2_k127_3969507_15 1358423.N180_10080 1.716e-34 132.0 COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IV39@117747|Sphingobacteriia 976|Bacteroidetes E GMC oxidoreductase - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 DYD2_k127_398442_3 1237149.C900_03149 3.862e-122 410.0 COG3209@1|root,COG4625@1|root,COG3209@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis rhgB - 4.2.2.23 ko:K07004,ko:K18195,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000 - PL4 - CBM-like,He_PIG,RhgB_N,SprB,fn3_3 DYD2_k127_398442_0 1237149.C900_03332 2.733e-182 574.0 COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD2_k127_398442_6 1237149.C900_03331 5.098e-47 178.0 COG0484@1|root,COG0484@2|Bacteria 2|Bacteria O heat shock protein binding - - - - - - - - - - - - - DYD2_k127_398442_1 1237149.C900_03330 1.211e-165 527.0 COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,47JH6@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C DYD2_k127_398442_4 1237149.C900_03329 1.888e-92 306.0 COG0521@1|root,COG0521@2|Bacteria,4PIS5@976|Bacteroidetes,47KA4@768503|Cytophagia 976|Bacteroidetes H Probable molybdopterin binding domain - - 2.7.7.75 ko:K03831 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth DYD2_k127_398442_2 1237149.C900_03328 6.679e-154 491.0 COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD2_k127_398442_5 1237149.C900_01565 1.37e-68 239.0 28MS7@1|root,2ZB0M@2|Bacteria,4NHCQ@976|Bacteroidetes,47JQ9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4034324_0 1237149.C900_01494 9.46e-260 823.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_4034324_1 143224.JQMD01000002_gene3578 9.317e-52 189.0 29VE2@1|root,30GUS@2|Bacteria,4NP29@976|Bacteroidetes,1I29M@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4034891_1 1237149.C900_05622 1.209e-107 355.0 COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia 976|Bacteroidetes C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ DYD2_k127_4034891_0 1296416.JACB01000003_gene721 2.898e-136 442.0 COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1HYZ9@117743|Flavobacteriia,2YIWZ@290174|Aquimarina 976|Bacteroidetes C NADH-ubiquinone oxidoreductase-F iron-sulfur binding region - - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S DYD2_k127_4082506_6 313606.M23134_01800 1.953e-136 439.0 COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47TXK@768503|Cytophagia 976|Bacteroidetes V ATPases associated with a variety of cellular activities gldA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_4082506_10 1408473.JHXO01000016_gene1933 1.031e-93 312.0 COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,2FT12@200643|Bacteroidia 976|Bacteroidetes S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 DYD2_k127_4082506_2 1408473.JHXO01000016_gene1934 2.623e-165 534.0 COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,2FR8P@200643|Bacteroidia 976|Bacteroidetes N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux DYD2_k127_4082506_14 869213.JCM21142_400 1.657e-31 135.0 2D6WA@1|root,32TMZ@2|Bacteria,4NU16@976|Bacteroidetes,47VUX@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 DYD2_k127_4082506_15 1237149.C900_03249 3.035e-27 112.0 COG0355@1|root,COG0355@2|Bacteria 2|Bacteria C proton-transporting ATP synthase activity, rotational mechanism atpC GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190 ATP-synt_DE,ATP-synt_DE_N DYD2_k127_4082506_0 1124780.ANNU01000042_gene644 6.948e-281 868.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,47KRX@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N DYD2_k127_4082506_4 1237149.C900_03247 2.814e-156 502.0 COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,47Y3V@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase vicK - - - - - - - - - - - HATPase_c DYD2_k127_4082506_5 1237149.C900_03246 1.907e-149 484.0 COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia 976|Bacteroidetes CP COGs COG1668 ABC-type Na efflux pump permease component natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD2_k127_4082506_8 1237149.C900_03245 1.766e-125 408.0 COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,47KYF@768503|Cytophagia 976|Bacteroidetes S PFAM ABC transporter natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 DYD2_k127_4082506_9 1237149.C900_03244 3.893e-100 334.0 2BK1P@1|root,32EEX@2|Bacteria,4NRXN@976|Bacteroidetes,47QMH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4082506_1 1237149.C900_03243 4.258e-175 555.0 COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,47MD9@768503|Cytophagia 976|Bacteroidetes O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD2_k127_4082506_13 643867.Ftrac_1940 3.64e-47 177.0 COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,47QCT@768503|Cytophagia 976|Bacteroidetes O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE DYD2_k127_4082506_3 1279009.ADICEAN_03111 1.592e-160 510.0 COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,47JCS@768503|Cytophagia 976|Bacteroidetes S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 DYD2_k127_4082506_11 1346330.M472_13795 1.047e-75 259.0 COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia 976|Bacteroidetes F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,Pribosyltran DYD2_k127_4082506_12 1237149.C900_03239 5.268e-59 210.0 COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,47PQ9@768503|Cytophagia 976|Bacteroidetes F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran DYD2_k127_4082506_7 1237149.C900_03238 1.907e-128 416.0 COG1363@1|root,COG1363@2|Bacteria,4NH34@976|Bacteroidetes,47MR1@768503|Cytophagia 976|Bacteroidetes G PFAM M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 DYD2_k127_4085280_7 1237149.C900_01737 4.35e-48 175.0 COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,47JPF@768503|Cytophagia 976|Bacteroidetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yafV - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase DYD2_k127_4085280_1 1237149.C900_01025 3.312e-229 719.0 COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,47JQT@768503|Cytophagia 976|Bacteroidetes F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS DYD2_k127_4085280_2 1237149.C900_01026 1.6e-200 627.0 COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,47JQ4@768503|Cytophagia 976|Bacteroidetes D TIGRFAM cell shape determining protein, MreB Mrl family mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD2_k127_4085280_4 1237149.C900_01027 3.591e-82 281.0 COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,47KWQ@768503|Cytophagia 976|Bacteroidetes M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC DYD2_k127_4085280_8 1237149.C900_01028 3.078e-44 166.0 2DXH2@1|root,34501@2|Bacteria,4P5GV@976|Bacteroidetes,47VZS@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4085280_0 1237149.C900_01029 4.33e-294 912.0 COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,47JSM@768503|Cytophagia 976|Bacteroidetes M Penicillin-binding protein, dimerisation domain mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase DYD2_k127_4085280_3 1237149.C900_01030 6.982e-175 557.0 COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,47JVQ@768503|Cytophagia 976|Bacteroidetes D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE DYD2_k127_4085280_6 1237149.C900_01031 4.096e-60 221.0 COG3827@1|root,COG3827@2|Bacteria,4PMMQ@976|Bacteroidetes,47Y53@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4085280_9 643867.Ftrac_2247 2.258e-31 126.0 COG0633@1|root,COG0633@2|Bacteria,4NX96@976|Bacteroidetes,47S8B@768503|Cytophagia 976|Bacteroidetes C PFAM 2Fe-2S iron-sulfur cluster binding domain - - - ko:K04755 - - - - ko00000 - - - Fer2 DYD2_k127_4085280_5 866536.Belba_0572 1.5e-73 252.0 COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,47JA6@768503|Cytophagia 976|Bacteroidetes F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK DYD2_k127_4085280_10 1237149.C900_01034 7.793e-24 105.0 COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,47M4V@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop DYD2_k127_4107157_1 388413.ALPR1_06230 2.021e-119 390.0 COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47N6X@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C DYD2_k127_4107157_3 195253.Syn6312_1034 3.15e-05 50.0 2EKBF@1|root,33E1U@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_4107157_2 1250232.JQNJ01000001_gene268 3.301e-85 285.0 COG0526@1|root,COG0526@2|Bacteria,4PKKF@976|Bacteroidetes,1IJBT@117743|Flavobacteriia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA DYD2_k127_4107157_0 1452718.JBOY01000082_gene2135 3.903e-197 624.0 COG0209@1|root,COG0209@2|Bacteria,1N0E3@1224|Proteobacteria 1224|Proteobacteria F Ribonucleotide reductase, barrel domain - - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC DYD2_k127_4168158_5 1237149.C900_03347 8.647e-122 393.0 COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia 976|Bacteroidetes D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge DYD2_k127_4168158_4 1121898.Q766_05980 1.436e-129 463.0 COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2NSCF@237|Flavobacterium 976|Bacteroidetes M SprB repeat - - - - - - - - - - - - CHU_C,Laminin_G_3,SprB DYD2_k127_4168158_14 929556.Solca_0601 1.642e-16 96.0 COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IRJP@117747|Sphingobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,DUF11,He_PIG DYD2_k127_4168158_7 1189612.A33Q_3107 1.543e-111 372.0 COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,47K6Q@768503|Cytophagia 976|Bacteroidetes C PFAM Acyl-CoA reductase (LuxC) - - - - - - - - - - - - LuxC DYD2_k127_4168158_9 1279009.ADICEAN_01172 2.622e-60 209.0 COG0437@1|root,COG0437@2|Bacteria,4PKQE@976|Bacteroidetes,47XYY@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S binding domain fdx - - - - - - - - - - - Fer4_7,Fer4_8 DYD2_k127_4168158_3 1237149.C900_05083 8.346e-132 426.0 COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,47JTH@768503|Cytophagia 976|Bacteroidetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 DYD2_k127_4168158_11 1237149.C900_05084 6.266e-50 181.0 2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,47R7K@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3276) - - - - - - - - - - - - DUF3276 DYD2_k127_4168158_1 1237149.C900_02461 9.239e-176 556.0 COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,47KXT@768503|Cytophagia 976|Bacteroidetes J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C DYD2_k127_4168158_8 1124780.ANNU01000066_gene375 8.344e-104 343.0 COG1583@1|root,COG1583@2|Bacteria,4NJ54@976|Bacteroidetes,47MMT@768503|Cytophagia 976|Bacteroidetes L PFAM CRISPR associated protein Cas6 - - - ko:K19091 - - - - ko00000,ko01000,ko02048 - - - Cas_Cas6 DYD2_k127_4168158_6 1237149.C900_02464 6.772e-119 395.0 28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,47MAE@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF5103) - - - - - - - - - - - - DUF5103 DYD2_k127_4168158_0 1237149.C900_02470 8.091e-280 872.0 COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,47KHA@768503|Cytophagia 976|Bacteroidetes S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn DYD2_k127_4168158_2 1237149.C900_02472 6.928e-175 555.0 COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MXD@768503|Cytophagia 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH DYD2_k127_4168158_12 1237149.C900_02061 3.986e-31 128.0 2DGJ8@1|root,2ZW7H@2|Bacteria,4P7SP@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4168158_10 1237149.C900_02479 1.614e-50 185.0 COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,47XP3@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 DYD2_k127_4168158_13 1279009.ADICEAN_01394 1.446e-17 81.0 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia 976|Bacteroidetes F PFAM Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 DYD2_k127_417865_17 1535422.ND16A_3875 2.59e-08 65.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,2Q73E@267889|Colwelliaceae 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 DYD2_k127_417865_18 746697.Aeqsu_2760 0.0001854 53.0 2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia 976|Bacteroidetes S TIR domain - - - - - - - - - - - - TIR_2 DYD2_k127_417865_8 1123057.P872_07695 3.474e-102 344.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_417865_1 671143.DAMO_2587 5.852e-219 689.0 COG0493@1|root,COG0493@2|Bacteria,2NNXN@2323|unclassified Bacteria 2|Bacteria E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltA - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,Pyr_redox_2 DYD2_k127_417865_3 671143.DAMO_2588 1.731e-150 493.0 COG0543@1|root,COG1413@1|root,COG0543@2|Bacteria,COG1413@2|Bacteria,2NNUA@2323|unclassified Bacteria 2|Bacteria CH Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B pyrK - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 ko:K00266,ko:K00528,ko:K02823 ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248,R10159 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2 DYD2_k127_417865_0 1173024.KI912153_gene216 0.0 1561.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae 1117|Cyanobacteria C Domain of unknown function - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C DYD2_k127_417865_5 118173.KB235910_gene4738 2.139e-129 421.0 COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1H82U@1150|Oscillatoriales 1117|Cyanobacteria F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh DYD2_k127_417865_9 1239962.C943_02139 8.195e-100 332.0 COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia 976|Bacteroidetes S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 DYD2_k127_417865_13 1123057.P872_16695 1.554e-55 196.0 2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes,47UWC@768503|Cytophagia 976|Bacteroidetes T PAS domain - - - - - - - - - - - - PAS_4,PAS_8 DYD2_k127_417865_12 643867.Ftrac_0532 6.304e-67 236.0 COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,47XPZ@768503|Cytophagia 976|Bacteroidetes S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP DYD2_k127_417865_6 1237149.C900_05565 6.264e-118 384.0 COG3279@1|root,COG3279@2|Bacteria,4NP0E@976|Bacteroidetes,47Q29@768503|Cytophagia 976|Bacteroidetes KT LytTr DNA-binding domain - - - - - - - - - - - - LytTR DYD2_k127_417865_11 1237149.C900_05564 5.653e-69 239.0 2D9XB@1|root,32TU6@2|Bacteria,4NSXG@976|Bacteroidetes,47R3J@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_417865_4 1237149.C900_05563 5.115e-148 478.0 COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes,47M8G@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase DYD2_k127_417865_10 926549.KI421517_gene3080 7.994e-84 287.0 COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,47MPJ@768503|Cytophagia 976|Bacteroidetes P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA DYD2_k127_417865_7 1121904.ARBP01000022_gene3484 1.841e-107 354.0 COG3568@1|root,COG3568@2|Bacteria,4NMQ9@976|Bacteroidetes,47M9K@768503|Cytophagia 976|Bacteroidetes S PFAM Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos DYD2_k127_417865_2 388413.ALPR1_18233 7.824e-213 672.0 COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47M14@768503|Cytophagia 976|Bacteroidetes G Peptidase, M28 PGCP - - - - - - - - - - - Peptidase_M28 DYD2_k127_417865_14 1122221.JHVI01000007_gene2170 1.422e-51 186.0 COG4101@1|root,COG4101@2|Bacteria 2|Bacteria G 3-hydroxyanthranilate 3,4-dioxygenase activity - - - - - - - - - - - - Cupin_2 DYD2_k127_417865_16 1121104.AQXH01000001_gene1189 6.312e-46 174.0 COG0823@1|root,COG0823@2|Bacteria,4NN6B@976|Bacteroidetes 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 DYD2_k127_4207516_0 313606.M23134_08430 1.068e-66 236.0 COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,47XHY@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 DYD2_k127_4207516_1 1237149.C900_01006 1.883e-52 190.0 COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,47P9F@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_4207516_4 700598.Niako_0412 0.0001232 53.0 COG0810@1|root,COG0810@2|Bacteria,4P6I7@976|Bacteroidetes,1IZ8I@117747|Sphingobacteriia 976|Bacteroidetes M Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - CarbopepD_reg_2,TonB_C DYD2_k127_4207516_3 1313301.AUGC01000010_gene981 9.653e-14 82.0 COG0810@1|root,COG0810@2|Bacteria,4NWK2@976|Bacteroidetes 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD2_k127_4207516_2 1356852.N008_09850 1.09e-26 113.0 COG2146@1|root,COG2146@2|Bacteria,4NV1B@976|Bacteroidetes,47S5J@768503|Cytophagia 976|Bacteroidetes P nitrite reductase [NAD(P)H] activity - - - - - - - - - - - - - DYD2_k127_4225757_7 1237149.C900_02857 3.439e-56 209.0 28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,47JR6@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4225757_6 1237149.C900_02856 1.33e-92 310.0 COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,47JZC@768503|Cytophagia 976|Bacteroidetes J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH - 2.1.1.185 ko:K03218,ko:K03437 - - - - ko00000,ko01000,ko03009,ko03016 - - - SpoU_methylase,SpoU_sub_bind DYD2_k127_4225757_5 1237149.C900_02746 9.378e-140 452.0 COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,47KJZ@768503|Cytophagia 976|Bacteroidetes M TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase manC - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD2_k127_4225757_4 1237149.C900_02747 1.127e-146 470.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,47KGF@768503|Cytophagia 976|Bacteroidetes M Belongs to the SIS family. GutQ KpsF subfamily kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS DYD2_k127_4225757_0 1237149.C900_02748 0.0 1132.0 COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,47JD8@768503|Cytophagia 976|Bacteroidetes L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind DYD2_k127_4225757_3 1237149.C900_02749 8.033e-172 548.0 COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,47JIA@768503|Cytophagia 976|Bacteroidetes F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N DYD2_k127_4225757_1 1237149.C900_02750 1.722e-175 557.0 COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,47M8P@768503|Cytophagia 976|Bacteroidetes S PFAM PSP1 C-terminal conserved region - - - - - - - - - - - - PSP1 DYD2_k127_4225757_8 1185876.BN8_06191 1.124e-35 141.0 2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,47PP1@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated lipoprotein, GldH gldH GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - GldH_lipo DYD2_k127_4225757_2 1237149.C900_03200 9.208e-174 555.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,47JV4@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG DYD2_k127_4249464_4 1237149.C900_05813 1.333e-16 83.0 COG0438@1|root,COG0438@2|Bacteria,4NMMT@976|Bacteroidetes,47PDF@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 DYD2_k127_4249464_2 1237149.C900_05811 1.699e-81 276.0 COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia 976|Bacteroidetes K Iron dependent repressor, metal binding and dimerisation domain - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA DYD2_k127_4249464_0 1341181.FLJC2902T_03730 1.094e-246 776.0 COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,1HXXF@117743|Flavobacteriia,2NTC3@237|Flavobacterium 976|Bacteroidetes PT H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp,Usp DYD2_k127_4249464_1 1120968.AUBX01000011_gene3056 1.561e-166 558.0 COG1629@1|root,COG1629@2|Bacteria,4NMTD@976|Bacteroidetes,47PTS@768503|Cytophagia 976|Bacteroidetes P CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug DYD2_k127_4249464_3 1189612.A33Q_2236 1.138e-78 286.0 COG1629@1|root,COG1629@2|Bacteria,4NMTD@976|Bacteroidetes,47PTS@768503|Cytophagia 976|Bacteroidetes P CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug DYD2_k127_4256187_2 313606.M23134_03066 7.736e-19 92.0 COG0653@1|root,COG0653@2|Bacteria 2|Bacteria U protein targeting secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD2_k127_4256187_1 411154.GFO_1525 1.37e-101 335.0 COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,1HXRU@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD2_k127_4256187_0 1237149.C900_02391 9.781e-303 938.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47P32@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_4292537_3 1124780.ANNU01000002_gene1575 8.918e-94 310.0 COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia 976|Bacteroidetes L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt DYD2_k127_4292537_4 1237149.C900_01569 1.431e-33 135.0 COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia 976|Bacteroidetes T PFAM Phosphoglycerate mutase sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 DYD2_k127_4292537_2 1237149.C900_01568 1.97e-145 468.0 COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia 976|Bacteroidetes E Belongs to the arginase family speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD2_k127_4292537_0 1237149.C900_01566 5.699e-171 548.0 COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47JCJ@768503|Cytophagia 976|Bacteroidetes E PFAM Sodium alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp DYD2_k127_4292537_1 1237149.C900_04771 2.874e-162 518.0 COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,47KX5@768503|Cytophagia 976|Bacteroidetes H Nicotinate-nucleotide adenylyltransferase - - - - - - - - - - - - - DYD2_k127_4380106_0 929556.Solca_2233 1.215e-127 413.0 COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S dicluster domain - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11 DYD2_k127_4380106_1 1121875.KB907546_gene2676 3.265e-69 244.0 COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1I0TY@117743|Flavobacteriia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - DYD2_k127_4380106_2 929556.Solca_2230 1.194e-13 75.0 COG2010@1|root,COG2010@2|Bacteria,4NYN7@976|Bacteroidetes 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - PSCyt1 DYD2_k127_4408068_8 497964.CfE428DRAFT_1447 0.0002323 46.0 COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia 74201|Verrucomicrobia OU PA domain - - - - - - - - - - - - PA,PD40,PDZ_2,Peptidase_M28 DYD2_k127_4408068_3 1121374.KB891589_gene45 8.016e-105 355.0 COG0733@1|root,COG0733@2|Bacteria,1NQUA@1224|Proteobacteria,1SN07@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - - - - - - - - - - SNF DYD2_k127_4408068_7 313606.M23134_04780 4.247e-32 128.0 COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,47QGA@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR DYD2_k127_4408068_2 1123277.KB893172_gene574 1.428e-170 567.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_4408068_5 1121324.CLIT_4c00250 3.928e-70 260.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,25RVB@186804|Peptostreptococcaceae 186801|Clostridia P CPA2 family - - - - - - - - - - - - Na_H_Exchanger DYD2_k127_4408068_1 313603.FB2170_08104 8.234e-206 665.0 COG2203@1|root,COG2203@2|Bacteria,4NE84@976|Bacteroidetes,1HXM4@117743|Flavobacteriia,2PG8J@252356|Maribacter 976|Bacteroidetes T Gaf domain - - - - - - - - - - - - - DYD2_k127_4408068_6 472759.Nhal_2487 8.411e-42 157.0 COG3809@1|root,COG3809@2|Bacteria,1NIWT@1224|Proteobacteria 1224|Proteobacteria S Transcription factor zinc-finger - - - ko:K09981 - - - - ko00000 - - - zf-TFIIB DYD2_k127_4408068_4 1237149.C900_02392 4.502e-98 325.0 COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,47RIH@768503|Cytophagia 976|Bacteroidetes M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - DUF4292,LolA_like DYD2_k127_4408068_0 1237149.C900_02391 2.437e-271 839.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47P32@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_4492597_2 1178825.ALIH01000003_gene2229 4.117e-171 542.0 COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,1I0SF@117743|Flavobacteriia 976|Bacteroidetes G Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_transf_4,Glyco_transf_5,Glycos_transf_1 DYD2_k127_4492597_0 1121875.KB907546_gene2404 1.795e-209 657.0 COG0448@1|root,COG0448@2|Bacteria,4NDVJ@976|Bacteroidetes,1HYK5@117743|Flavobacteriia 976|Bacteroidetes G Catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase DYD2_k127_4492597_3 1121373.KB903654_gene1587 8.983e-112 376.0 COG1538@1|root,COG1538@2|Bacteria,4NKWK@976|Bacteroidetes,47VSF@768503|Cytophagia 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP DYD2_k127_4492597_4 1249997.JHZW01000003_gene3756 4.141e-31 128.0 COG2318@1|root,COG2318@2|Bacteria,4NS3A@976|Bacteroidetes,1I2YI@117743|Flavobacteriia,2PHZB@252356|Maribacter 976|Bacteroidetes S DinB family - - - - - - - - - - - - DinB,DinB_2 DYD2_k127_4492597_5 1121373.KB903643_gene3566 8.022e-30 128.0 COG0457@1|root,COG0457@2|Bacteria,4NXAA@976|Bacteroidetes,47XR9@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - DUF4071 DYD2_k127_4492597_1 1237149.C900_05696 6.648e-208 665.0 COG1520@1|root,COG1520@2|Bacteria,4NMP7@976|Bacteroidetes 976|Bacteroidetes S PQQ-like domain - - - - - - - - - - - - PQQ_2 DYD2_k127_4492597_6 1408473.JHXO01000005_gene1676 1.267e-27 113.0 COG1051@1|root,COG1051@2|Bacteria,4PMRX@976|Bacteroidetes 976|Bacteroidetes F NUDIX domain - - - - - - - - - - - - NUDIX DYD2_k127_4520331_13 643867.Ftrac_2551 3.268e-120 397.0 COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,47JXR@768503|Cytophagia 976|Bacteroidetes H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM DYD2_k127_4520331_23 1237149.C900_04583 1.726e-42 158.0 2D41J@1|root,32TG2@2|Bacteria,4NTNX@976|Bacteroidetes,47RJ7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4520331_14 1237149.C900_04582 5.143e-117 379.0 COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg DYD2_k127_4520331_15 1124780.ANNU01000006_gene2947 5.124e-103 346.0 COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase DYD2_k127_4520331_0 1237149.C900_04576 0.0 1575.0 COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,47K0C@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD2_k127_4520331_16 1122179.KB890418_gene3822 8.175e-91 327.0 COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NKC3@976|Bacteroidetes 976|Bacteroidetes C WD domain, G-beta repeat - - - - - - - - - - - - Peptidase_C14,WD40 DYD2_k127_4520331_27 926551.KB900715_gene2201 2.966e-08 57.0 2DFVK@1|root,2ZTBH@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_4520331_21 1237149.C900_00803 3.247e-46 173.0 29TMV@1|root,30EVG@2|Bacteria,4NNPM@976|Bacteroidetes,47RB5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4520331_8 1121904.ARBP01000002_gene6983 4.015e-177 582.0 COG4206@1|root,COG4206@2|Bacteria,4PKF2@976|Bacteroidetes,47JDS@768503|Cytophagia 976|Bacteroidetes H TonB-dependent Receptor Plug - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_4520331_24 1120971.AUCA01000005_gene2264 2.449e-40 151.0 COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,4HMGX@91061|Bacilli 91061|Bacilli S CHY zinc finger - - - - - - - - - - - - zf-CHY DYD2_k127_4520331_25 1120951.AUBG01000002_gene1371 4.914e-26 108.0 2BZQB@1|root,32Y98@2|Bacteria,4NVDQ@976|Bacteroidetes,1I5G0@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4520331_10 1305737.JAFX01000001_gene1212 8.599e-154 488.0 COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,47N4V@768503|Cytophagia 976|Bacteroidetes I PFAM Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase DYD2_k127_4520331_3 1250232.JQNJ01000001_gene1599 9.586e-230 719.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1HYF1@117743|Flavobacteriia 976|Bacteroidetes P COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B,Rhodanese DYD2_k127_4520331_9 1237149.C900_04556 2.745e-167 529.0 COG1398@1|root,COG1398@2|Bacteria,4NJI9@976|Bacteroidetes,47XKP@768503|Cytophagia 976|Bacteroidetes I Fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase DYD2_k127_4520331_1 1237149.C900_04554 0.0 1296.0 COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,47JE2@768503|Cytophagia 976|Bacteroidetes L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V DYD2_k127_4520331_20 1250232.JQNJ01000001_gene3351 3.492e-49 184.0 COG4798@1|root,COG4798@2|Bacteria,4NII9@976|Bacteroidetes,1IJX2@117743|Flavobacteriia 976|Bacteroidetes S Fibrillarin - - - - - - - - - - - - Methyltransf_12,Methyltransf_25,Methyltransf_31 DYD2_k127_4520331_19 1237149.C900_04552 9.516e-65 226.0 COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,47PEY@768503|Cytophagia 976|Bacteroidetes J PFAM SpoU rRNA Methylase family spoU - - - - - - - - - - - SpoU_methylase DYD2_k127_4520331_4 643867.Ftrac_2021 5.934e-202 634.0 COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,47JG0@768503|Cytophagia 976|Bacteroidetes F PFAM AIR synthase related protein purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD2_k127_4520331_2 1237149.C900_00894 5.219e-243 767.0 COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia 976|Bacteroidetes MU Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA,PD40,TPR_16,TPR_2,TPR_8 DYD2_k127_4520331_22 1237149.C900_00895 1.148e-44 168.0 28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,47RCF@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4520331_11 643867.Ftrac_2753 6.131e-147 467.0 COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,47KRT@768503|Cytophagia 976|Bacteroidetes C PFAM Cysteine-rich domain - - - - - - - - - - - - CCG DYD2_k127_4520331_5 1305737.JAFX01000001_gene2160 2.472e-198 627.0 COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,47JED@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_8,Fer4_9 DYD2_k127_4520331_26 1237149.C900_01500 1.68e-17 86.0 COG2827@1|root,COG2827@2|Bacteria,4NUKY@976|Bacteroidetes 976|Bacteroidetes L GIY-YIG catalytic domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD2_k127_4520331_12 1124780.ANNU01000025_gene3411 1.183e-141 461.0 COG2081@1|root,COG2081@2|Bacteria,4NFME@976|Bacteroidetes,47JD1@768503|Cytophagia 976|Bacteroidetes S TIGRFAM flavoprotein, HI0933 family yhiN - - ko:K07007 - - - - ko00000 - - - HI0933_like DYD2_k127_4520331_6 1237149.C900_00811 6.406e-187 591.0 COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,47JBT@768503|Cytophagia 976|Bacteroidetes E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC DYD2_k127_4520331_17 643867.Ftrac_1787 1.115e-89 302.0 COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,47JB4@768503|Cytophagia 976|Bacteroidetes S Serine aminopeptidase, S33 ybfF - - - - - - - - - - - Abhydrolase_1 DYD2_k127_4520331_18 1239962.C943_03199 2.19e-76 262.0 COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,47N4G@768503|Cytophagia 976|Bacteroidetes H PFAM Tetrapyrrole (Corrin Porphyrin) Methylases rsmI_1 - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase DYD2_k127_4520331_7 485918.Cpin_3691 6.344e-181 569.0 COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N DYD2_k127_4568452_4 926560.KE387023_gene2600 8.123e-46 169.0 COG3823@1|root,COG3823@2|Bacteria,1WM89@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 DYD2_k127_4568452_8 991.IW20_01815 2.26e-35 141.0 2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes,1I25Z@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4568452_3 1086011.HJ01_00029 9.327e-55 202.0 COG0223@1|root,COG0223@2|Bacteria,4NICR@976|Bacteroidetes,1I5B3@117743|Flavobacteriia 976|Bacteroidetes J Formyl transferase - - - - - - - - - - - - Formyl_trans_N DYD2_k127_4568452_9 643867.Ftrac_1661 4.257e-23 102.0 COG3012@1|root,COG3012@2|Bacteria 2|Bacteria - - secA_2 - - - - - - - - - - - SEC-C DYD2_k127_4568452_7 1250232.JQNJ01000001_gene1605 1.392e-37 146.0 2E0TJ@1|root,32WB7@2|Bacteria,4NTAN@976|Bacteroidetes,1I25N@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4568452_0 1249997.JHZW01000003_gene2592 1.753e-197 622.0 COG2041@1|root,COG2041@2|Bacteria,4NEIQ@976|Bacteroidetes,1I0IA@117743|Flavobacteriia,2PGDD@252356|Maribacter 976|Bacteroidetes S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb DYD2_k127_4568452_1 1239962.C943_04519 1.898e-178 572.0 COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,47KU0@768503|Cytophagia 976|Bacteroidetes E Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 DYD2_k127_4568452_2 190650.CC_3125 6.446e-142 464.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U0BD@28211|Alphaproteobacteria,2KK0G@204458|Caulobacterales 204458|Caulobacterales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD2_k127_4568452_11 240015.ACP_0708 3.341e-16 85.0 2B4YW@1|root,31XRX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_4568452_5 1237149.C900_03337 9.308e-43 163.0 295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,47W1I@768503|Cytophagia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - DYD2_k127_4568452_6 1237149.C900_03336 3.891e-42 156.0 COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,47V9T@768503|Cytophagia 976|Bacteroidetes K Winged helix DNA-binding domain marR - - - - - - - - - - - HTH_34 DYD2_k127_4568452_10 237727.NAP1_03925 7.201e-19 91.0 2B1V3@1|root,31UB3@2|Bacteria,1QS5N@1224|Proteobacteria,2V1CH@28211|Alphaproteobacteria,2KBDC@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD2_k127_47177_10 1237149.C900_01088 2.862e-113 375.0 COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,47JIS@768503|Cytophagia 976|Bacteroidetes M Organic solvent tolerance protein OstA - - - - - - - - - - - - - DYD2_k127_47177_0 1237149.C900_01087 1.712e-312 963.0 COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,47M2W@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DUF4332,tRNA-synt_2,tRNA_anti-codon DYD2_k127_47177_4 1237149.C900_01083 3.311e-165 527.0 COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,47KMP@768503|Cytophagia 976|Bacteroidetes E PFAM Proline dehydrogenase putA - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh DYD2_k127_47177_6 313606.M23134_08406 1.851e-140 455.0 COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia 976|Bacteroidetes E chorismate mutase pheB - 5.4.99.5 ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,DAHP_synth_1 DYD2_k127_47177_9 1237149.C900_01081 1.233e-117 388.0 COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,47JBE@768503|Cytophagia 976|Bacteroidetes E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase DYD2_k127_47177_8 866536.Belba_2278 2.081e-125 413.0 COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,47K1U@768503|Cytophagia 976|Bacteroidetes E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase DYD2_k127_47177_5 985255.APHJ01000039_gene248 2.469e-148 485.0 COG1228@1|root,COG1228@2|Bacteria,4NGJV@976|Bacteroidetes,1I000@117743|Flavobacteriia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD2_k127_47177_2 1089547.KB913013_gene1137 4.072e-180 569.0 COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,47MIG@768503|Cytophagia 976|Bacteroidetes G PFAM M42 glutamyl aminopeptidase frvX - - - - - - - - - - - Peptidase_M42 DYD2_k127_47177_1 1237149.C900_01071 5.984e-289 892.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) pccB - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD2_k127_47177_11 1279009.ADICEAN_00835 4.026e-96 323.0 COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,47K3H@768503|Cytophagia 976|Bacteroidetes FP Ppx GppA phosphatase - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA DYD2_k127_47177_7 153721.MYP_4777 1.84e-139 460.0 COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,47MYA@768503|Cytophagia 976|Bacteroidetes S N-terminal domain of unknown function (DUF4140) - - - - - - - - - - - - DUF4139,DUF4140 DYD2_k127_47177_3 1237149.C900_01069 6.8e-172 545.0 COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47KBZ@768503|Cytophagia 976|Bacteroidetes C Belongs to the LDH2 MDH2 oxidoreductase family - - - - - - - - - - - - Ldh_2 DYD2_k127_47177_12 1237149.C900_01068 5.493e-17 85.0 COG2067@1|root,COG2067@2|Bacteria,4PMEK@976|Bacteroidetes,47QPW@768503|Cytophagia 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - - DYD2_k127_4747084_2 866536.Belba_0146 1.278e-236 736.0 COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,47KGI@768503|Cytophagia 976|Bacteroidetes H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD DYD2_k127_4747084_25 153721.MYP_4471 3.201e-80 272.0 COG2761@1|root,COG2761@2|Bacteria,4NJ3N@976|Bacteroidetes,47NV7@768503|Cytophagia 976|Bacteroidetes Q dithiol-disulfide isomerase involved in polyketide biosynthesis - - 5.3.4.1 ko:K01829 - - - - ko00000,ko01000 - - - DSBA DYD2_k127_4747084_11 1237149.C900_01850 1.095e-163 526.0 COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2 DYD2_k127_4747084_45 269798.CHU_0933 3.591e-11 69.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - DYD2_k127_4747084_4 1380600.AUYN01000001_gene2831 2.99e-216 684.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HYK7@117743|Flavobacteriia 976|Bacteroidetes S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 DYD2_k127_4747084_23 760192.Halhy_0717 4.517e-82 274.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1IWSE@117747|Sphingobacteriia 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 DYD2_k127_4747084_0 1237149.C900_02598 0.0 1136.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD2_k127_4747084_1 1123277.KB893194_gene5874 2.191e-305 957.0 COG1680@1|root,COG3653@1|root,COG1680@2|Bacteria,COG3653@2|Bacteria,4NI1Z@976|Bacteroidetes,47NHH@768503|Cytophagia 976|Bacteroidetes QV Beta-lactamase - - - - - - - - - - - - Amidohydro_3,Beta-lactamase DYD2_k127_4747084_13 643867.Ftrac_2937 3.902e-150 493.0 COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes,47U9R@768503|Cytophagia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - DYD2_k127_4747084_37 1391647.AVSV01000013_gene2813 1.415e-35 146.0 COG1597@1|root,COG1597@2|Bacteria,1V1DP@1239|Firmicutes,25CN2@186801|Clostridia,36HD9@31979|Clostridiaceae 186801|Clostridia I Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat DYD2_k127_4747084_8 1123278.KB893400_gene4134 6.328e-178 566.0 COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,47N08@768503|Cytophagia 976|Bacteroidetes EGP Major facilitator superfamily tetA - - ko:K08151 - M00668 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75 - - MFS_1,Sugar_tr DYD2_k127_4747084_20 926562.Oweho_2064 7.821e-95 320.0 COG0745@1|root,COG0745@2|Bacteria,4NE77@976|Bacteroidetes,1IMIZ@117743|Flavobacteriia 976|Bacteroidetes T transcriptional regulator - - - ko:K07665 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C DYD2_k127_4747084_12 926562.Oweho_2065 5.173e-163 524.0 COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,4NEIS@976|Bacteroidetes,1HXGB@117743|Flavobacteriia,2PBKD@246874|Cryomorphaceae 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase arlS_1 - - - - - - - - - - - HAMP,HATPase_c,HisKA DYD2_k127_4747084_36 926562.Oweho_2066 5.775e-40 159.0 COG3074@1|root,COG3074@2|Bacteria 2|Bacteria D FtsZ-dependent cytokinesis zapB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044424,GO:0044444,GO:0044464,GO:0051301 2.1.1.80,3.1.1.61 ko:K09892,ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03036 - - - ZapB DYD2_k127_4747084_35 504472.Slin_4697 3.007e-44 167.0 COG0607@1|root,COG1996@1|root,COG0607@2|Bacteria,COG1996@2|Bacteria,4PIDM@976|Bacteroidetes,47X19@768503|Cytophagia 976|Bacteroidetes P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese DYD2_k127_4747084_32 1124780.ANNU01000056_gene3483 1.477e-66 232.0 COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,47P9D@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised protein family UPF0029, Impact, N-terminal yigZ - - - - - - - - - - - UPF0029 DYD2_k127_4747084_40 1168034.FH5T_10660 1.278e-32 138.0 COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,2FUXZ@200643|Bacteroidia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 DYD2_k127_4747084_39 866536.Belba_1394 4.969e-33 136.0 COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,47RZ2@768503|Cytophagia 976|Bacteroidetes S PFAM YhhN-like protein - - - - - - - - - - - - YhhN DYD2_k127_4747084_16 1237149.C900_05494 9.446e-132 431.0 COG0477@1|root,COG2814@2|Bacteria,4NE7F@976|Bacteroidetes,47MD0@768503|Cytophagia 976|Bacteroidetes EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr DYD2_k127_4747084_9 1237149.C900_05493 2.63e-166 528.0 COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,47KHU@768503|Cytophagia 976|Bacteroidetes J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD2_k127_4747084_49 1237149.C900_05492 0.0004768 49.0 2CH9X@1|root,33DG6@2|Bacteria,4NYSM@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4747084_10 643867.Ftrac_0939 2.257e-165 527.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia 976|Bacteroidetes EH Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD2_k127_4747084_27 1237149.C900_05490 5.019e-79 267.0 COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,47P8Y@768503|Cytophagia 976|Bacteroidetes S PFAM Cobalamin adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans DYD2_k127_4747084_18 1237149.C900_05489 4.527e-124 400.0 COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,47KDU@768503|Cytophagia 976|Bacteroidetes V ABC transporter macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_4747084_29 558169.AGAV01000005_gene2268 7.326e-75 259.0 COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4HCA1@91061|Bacilli 91061|Bacilli S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 DYD2_k127_4747084_24 1121904.ARBP01000010_gene2408 1.638e-80 272.0 COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,47KXS@768503|Cytophagia 976|Bacteroidetes L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII DYD2_k127_4747084_30 1120968.AUBX01000009_gene624 1.263e-74 254.0 COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,47P7M@768503|Cytophagia 976|Bacteroidetes L pfam nudix nudF - - - - - - - - - - - NUDIX DYD2_k127_4747084_14 1237149.C900_01857 1.536e-149 486.0 COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,47KYV@768503|Cytophagia 976|Bacteroidetes V efflux protein, MATE family norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD2_k127_4747084_28 1237149.C900_04003 3.475e-78 265.0 COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,47N9Z@768503|Cytophagia 976|Bacteroidetes I PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT DYD2_k127_4747084_5 1121104.AQXH01000003_gene415 4.588e-191 604.0 COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1IV0D@117747|Sphingobacteriia 976|Bacteroidetes E Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 DYD2_k127_4747084_22 1237149.C900_04001 7.473e-84 284.0 COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47JI7@768503|Cytophagia 976|Bacteroidetes I TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD2_k127_4747084_41 1237149.C900_04000 6.875e-31 123.0 COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,47QCX@768503|Cytophagia 976|Bacteroidetes J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln DYD2_k127_4747084_33 1123278.KB893388_gene5681 4.591e-54 194.0 COG1247@1|root,COG1247@2|Bacteria,4NRD5@976|Bacteroidetes,47QE1@768503|Cytophagia 976|Bacteroidetes M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 DYD2_k127_4747084_6 1237149.C900_03999 1.026e-189 628.0 COG0457@1|root,COG0457@2|Bacteria,4NGQ7@976|Bacteroidetes,47KHQ@768503|Cytophagia 976|Bacteroidetes U Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 DYD2_k127_4747084_7 1237149.C900_03998 8.66e-184 580.0 COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,47MN7@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C DYD2_k127_4747084_26 643867.Ftrac_1906 1.345e-79 272.0 COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,47M1W@768503|Cytophagia 976|Bacteroidetes H Belongs to the ComB family comB - 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 - - - 2-ph_phosp DYD2_k127_4747084_34 1237149.C900_03996 1.229e-48 175.0 COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,47QEV@768503|Cytophagia 976|Bacteroidetes S PFAM MazG nucleotide pyrophosphohydrolase ypjD - - - - - - - - - - - MazG DYD2_k127_4747084_31 509635.N824_11440 2.079e-68 239.0 COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1IS0X@117747|Sphingobacteriia 976|Bacteroidetes M Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide vanX - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 DYD2_k127_4747084_3 1120966.AUBU01000003_gene1679 7.077e-227 727.0 COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47KXN@768503|Cytophagia 976|Bacteroidetes S Penicillin amidase pac - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase DYD2_k127_4747084_19 479435.Kfla_3561 1.324e-121 401.0 COG0520@1|root,COG0520@2|Bacteria,2H9MG@201174|Actinobacteria,4DUIC@85009|Propionibacteriales 201174|Actinobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family egtE - - - - - - - - - - - Aminotran_5 DYD2_k127_4747084_46 402881.Plav_2208 5.374e-08 61.0 COG2717@1|root,COG2717@2|Bacteria,1R4CY@1224|Proteobacteria,2U37R@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - - - - - - - - - - Ferric_reduct DYD2_k127_4747084_17 1237149.C900_05303 1.59e-127 413.0 COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,47JW8@768503|Cytophagia 976|Bacteroidetes O membrane protease - - - - - - - - - - - - Band_7 DYD2_k127_4747084_42 1121011.AUCB01000006_gene1045 8.109e-28 119.0 2E30A@1|root,32Y0V@2|Bacteria,4NPVG@976|Bacteroidetes,1I2I5@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF1705 DYD2_k127_4747084_44 1237149.C900_05301 7.963e-18 83.0 COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,47T6F@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Arc,RHH_5 DYD2_k127_4747084_15 1288963.ADIS_3842 2.46e-136 445.0 COG0144@1|root,COG0144@2|Bacteria,4NEV7@976|Bacteroidetes,47NAK@768503|Cytophagia 976|Bacteroidetes J TIGRFAM ribosomal RNA small subunit methyltransferase RsmB rsmB - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N DYD2_k127_4747084_21 1237149.C900_05843 2.175e-86 291.0 COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47QIE@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD2_k127_4747084_47 1121012.AUKX01000012_gene2281 6.48e-07 58.0 2E3Y0@1|root,32YV0@2|Bacteria,4NVQW@976|Bacteroidetes,1I557@117743|Flavobacteriia,23HMR@178469|Arenibacter 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4747084_43 1121899.Q764_00235 2.229e-23 103.0 COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,1I4DC@117743|Flavobacteriia,2NWFY@237|Flavobacterium 976|Bacteroidetes U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB DYD2_k127_4747084_48 1313421.JHBV01000138_gene1207 2.125e-06 55.0 2DPQ3@1|root,332XU@2|Bacteria,4NX0W@976|Bacteroidetes,1IU7V@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4747084_38 1122179.KB890427_gene3865 1.706e-34 150.0 COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1ISQ8@117747|Sphingobacteriia 976|Bacteroidetes UW domain, Protein - - - - - - - - - - - - Collagen,Peptidase_S74 DYD2_k127_4763407_3 1237149.C900_02567 3.987e-214 673.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JR2@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_4763407_0 468059.AUHA01000004_gene2204 0.0 1053.0 COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,1IRII@117747|Sphingobacteriia 976|Bacteroidetes G phosphorylase - - 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m DYD2_k127_4763407_19 1321778.HMPREF1982_00965 6.43e-69 240.0 COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia 186801|Clostridia S Haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED pgmB - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 DYD2_k127_4763407_8 643867.Ftrac_0734 1.365e-131 428.0 COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47MGC@768503|Cytophagia 976|Bacteroidetes K PFAM Periplasmic binding protein LacI transcriptional regulator cytR - - ko:K02529,ko:K05499 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 DYD2_k127_4763407_1 1237149.C900_04352 0.0 1026.0 COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,47NQ6@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31 DYD2_k127_4763407_4 1237149.C900_04350 9.969e-206 655.0 COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,47KS1@768503|Cytophagia 976|Bacteroidetes G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 DYD2_k127_4763407_9 1237149.C900_03327 5.541e-122 398.0 COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,47M8W@768503|Cytophagia 976|Bacteroidetes E ATP phosphoribosyltransferase hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C DYD2_k127_4763407_5 1313421.JHBV01000043_gene3118 6.645e-159 512.0 COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1IQWR@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh DYD2_k127_4763407_10 1123248.KB893326_gene1321 1.581e-118 390.0 COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,1IQ0J@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_4763407_6 1121904.ARBP01000006_gene4051 9.601e-156 498.0 COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,47J9I@768503|Cytophagia 976|Bacteroidetes E belongs to the imidazoleglycerol-phosphate dehydratase family hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_like,IGPD,PNK3P DYD2_k127_4763407_16 385682.AFSL01000040_gene247 3.95e-77 263.0 COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,2FPAY@200643|Bacteroidia,3XJ5U@558415|Marinilabiliaceae 976|Bacteroidetes E SNO glutamine amidotransferase family hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase DYD2_k127_4763407_17 1237149.C900_03322 1.683e-76 263.0 COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,47M7D@768503|Cytophagia 976|Bacteroidetes E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD2_k127_4763407_11 1237149.C900_03321 4.966e-111 363.0 COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,47K9T@768503|Cytophagia 976|Bacteroidetes E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD2_k127_4763407_18 1120968.AUBX01000014_gene2464 1.686e-72 250.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,47KYT@768503|Cytophagia 976|Bacteroidetes E Belongs to the PRA-CH family hisI - 3.5.4.19,3.6.1.31 ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH,PRA-PH DYD2_k127_4763407_12 1237149.C900_03318 1.205e-109 358.0 COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia 976|Bacteroidetes C Nitroreductase family - - - - - - - - - - - - Nitroreductase DYD2_k127_4763407_20 1122176.KB903539_gene1373 6.649e-66 228.0 COG0783@1|root,COG0783@2|Bacteria,4NQDD@976|Bacteroidetes,1ISAY@117747|Sphingobacteriia 976|Bacteroidetes P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin DYD2_k127_4763407_2 1237149.C900_03312 6.055e-257 799.0 COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,47NRN@768503|Cytophagia 976|Bacteroidetes C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim DYD2_k127_4763407_15 869213.JCM21142_93780 3.852e-88 301.0 COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,47KEY@768503|Cytophagia 976|Bacteroidetes S Amidinotransferase - - - - - - - - - - - - Amidinotransf DYD2_k127_4763407_21 1237149.C900_03339 7.374e-62 218.0 COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,47RBP@768503|Cytophagia 976|Bacteroidetes I PFAM PAP2 superfamily ybjG GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 DYD2_k127_4763407_14 1237149.C900_03338 1.32e-89 299.0 COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,47TX8@768503|Cytophagia 976|Bacteroidetes H Lumazine binding domain ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding DYD2_k127_4763407_7 1454007.JAUG01000047_gene512 2.371e-135 439.0 COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD2_k127_4763407_23 641524.ADICYQ_5597 1.17e-53 194.0 COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes,47PGS@768503|Cytophagia 976|Bacteroidetes M Lamin Tail Domain - - - - - - - - - - - - CHB_HEX_C_1,CotH,Fn3_assoc,LTD DYD2_k127_4763407_24 1123057.P872_07690 5.991e-52 189.0 COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,47XX2@768503|Cytophagia 976|Bacteroidetes S Phosphohydrolase - - - - - - - - - - - - HD DYD2_k127_4763407_22 1237149.C900_01350 1.995e-55 204.0 COG2992@1|root,COG2992@2|Bacteria 2|Bacteria S amidase activity bax - - ko:K03796 - - - - ko00000 - GH73 - Glucosaminidase DYD2_k127_4763407_13 1237149.C900_01351 9.714e-102 343.0 COG0726@1|root,COG0726@2|Bacteria,4NXPA@976|Bacteroidetes,47XNH@768503|Cytophagia 976|Bacteroidetes G Polysaccharide deacetylase - - 3.5.1.41 ko:K01452 ko00520,ko01100,map00520,map01100 - R02333 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Polysacc_deac_1 DYD2_k127_4763407_25 1336803.PHEL49_0558 1.133e-38 149.0 COG3823@1|root,COG3823@2|Bacteria,4NF2M@976|Bacteroidetes,1HY29@117743|Flavobacteriia,3VV6Q@52959|Polaribacter 976|Bacteroidetes M Glutamine cyclotransferase - - 2.3.2.5 ko:K00683 - - - - ko00000,ko01000 - - - Glu_cyclase_2 DYD2_k127_4783626_27 1237149.C900_02791 1.093e-53 192.0 COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,47PIE@768503|Cytophagia 976|Bacteroidetes O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH - - - ko:K02197 - - - - ko00000 - - - CcmE DYD2_k127_4783626_0 1237149.C900_02790 0.0 1139.0 COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia 976|Bacteroidetes O PFAM Cytochrome c assembly protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD2_k127_4783626_12 1279009.ADICEAN_02206 7.434e-156 497.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47KTK@768503|Cytophagia 976|Bacteroidetes S PFAM ATPase associated with various cellular activities moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD2_k127_4783626_9 1237149.C900_03123 3.709e-165 531.0 COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,47JPW@768503|Cytophagia 976|Bacteroidetes O peptidyl-prolyl isomerase surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N_3 DYD2_k127_4783626_32 927658.AJUM01000022_gene999 4.148e-35 145.0 COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,2FMWD@200643|Bacteroidia,3XJ11@558415|Marinilabiliaceae 976|Bacteroidetes O COG NOG23400 non supervised orthologous group - - - - - - - - - - - - Rotamase_2 DYD2_k127_4783626_10 1237149.C900_03125 4.774e-159 523.0 COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia 976|Bacteroidetes O peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 DYD2_k127_4783626_38 925409.KI911562_gene53 1.348e-10 68.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - - - - - - - - - - AhpC-TSA,Thioredoxin,Thioredoxin_8 DYD2_k127_4783626_31 1121904.ARBP01000012_gene1187 1.638e-35 139.0 COG2172@1|root,COG2172@2|Bacteria,4NV3J@976|Bacteroidetes,47RU2@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 DYD2_k127_4783626_30 1237149.C900_03127 1.886e-36 141.0 COG1366@1|root,COG1366@2|Bacteria,4NVHQ@976|Bacteroidetes,47RVX@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS DYD2_k127_4783626_4 1237149.C900_03128 2.128e-249 787.0 COG2208@1|root,COG2208@2|Bacteria,4NJMJ@976|Bacteroidetes,47JNJ@768503|Cytophagia 976|Bacteroidetes KT PFAM Stage II sporulation protein E (SpoIIE) - - - - - - - - - - - - GAF_2,SpoIIE DYD2_k127_4783626_5 1237149.C900_03138 2e-240 750.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,47KQV@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH DYD2_k127_4783626_23 643867.Ftrac_1853 2.909e-69 242.0 COG0797@1|root,COG0797@2|Bacteria,4NSF1@976|Bacteroidetes,47RE3@768503|Cytophagia 976|Bacteroidetes M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR DYD2_k127_4783626_19 1279009.ADICEAN_01503 3.987e-87 295.0 COG0730@1|root,COG0730@2|Bacteria,4NFWP@976|Bacteroidetes,47KYB@768503|Cytophagia 976|Bacteroidetes S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE DYD2_k127_4783626_29 866536.Belba_0299 1.985e-41 154.0 COG3118@1|root,COG3118@2|Bacteria,4NS6N@976|Bacteroidetes,47R18@768503|Cytophagia 976|Bacteroidetes O Belongs to the thioredoxin family - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD2_k127_4783626_20 1121904.ARBP01000040_gene520 1.346e-75 259.0 COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,47P97@768503|Cytophagia 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N DYD2_k127_4783626_6 1237149.C900_02636 9.677e-238 755.0 COG2274@1|root,COG2274@2|Bacteria,4NFJF@976|Bacteroidetes,47K3G@768503|Cytophagia 976|Bacteroidetes V PFAM ABC transporter - - - - - - - - - - - - ABC_membrane,ABC_tran DYD2_k127_4783626_11 1237149.C900_02637 1.031e-156 505.0 COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,47JV7@768503|Cytophagia 976|Bacteroidetes M Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,OEP DYD2_k127_4783626_14 1237149.C900_02638 9.738e-123 409.0 COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,47JKK@768503|Cytophagia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP DYD2_k127_4783626_17 1237149.C900_03142 7.577e-101 346.0 COG1231@1|root,COG1231@2|Bacteria,4NKW2@976|Bacteroidetes,47NSQ@768503|Cytophagia 976|Bacteroidetes E Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase DYD2_k127_4783626_26 1237149.C900_03144 5.28e-56 200.0 COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,47QMU@768503|Cytophagia 976|Bacteroidetes H ATPase kinase involved in NAD metabolism nadR - - - - - - - - - - - AAA_28 DYD2_k127_4783626_13 153721.MYP_4138 1.081e-133 439.0 COG2270@1|root,COG2270@2|Bacteria,4PKPY@976|Bacteroidetes 976|Bacteroidetes S Transmembrane secretion effector - - - - - - - - - - - - MFS_3 DYD2_k127_4783626_2 760192.Halhy_6351 4.173e-296 928.0 COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1IPU7@117747|Sphingobacteriia 976|Bacteroidetes S COG2366 Protein related to penicillin acylase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase DYD2_k127_4783626_37 760192.Halhy_1935 3.599e-19 89.0 2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1IZFK@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 DYD2_k127_4783626_34 1237149.C900_00366 1.265e-31 130.0 COG1238@1|root,COG1238@2|Bacteria,4NMW6@976|Bacteroidetes,47VDA@768503|Cytophagia 976|Bacteroidetes I metal cluster binding - - - - - - - - - - - - SNARE_assoc DYD2_k127_4783626_8 1237149.C900_00365 8.457e-177 561.0 COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia 976|Bacteroidetes K Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - DYD2_k127_4783626_21 313606.M23134_00080 7.767e-72 252.0 COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes 976|Bacteroidetes K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - - - - - - - - - - DJ-1_PfpI DYD2_k127_4783626_33 926549.KI421517_gene1459 1.665e-32 134.0 COG0500@1|root,COG2226@2|Bacteria,4NSPB@976|Bacteroidetes,47RD0@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_12,Methyltransf_2,Methyltransf_25 DYD2_k127_4783626_35 1237149.C900_00361 2.145e-31 134.0 2E39A@1|root,32Y8X@2|Bacteria,4NWB4@976|Bacteroidetes,47SFE@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - UbiA DYD2_k127_4783626_15 1237149.C900_04606 4.734e-118 385.0 COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,47JM0@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt DYD2_k127_4783626_3 1237149.C900_04605 1.775e-279 865.0 COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,47JFI@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N DYD2_k127_4783626_24 1237149.C900_04604 4.761e-62 218.0 COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia 976|Bacteroidetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP DYD2_k127_4783626_28 1305737.JAFX01000001_gene2325 2.077e-47 175.0 COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,47Q9K@768503|Cytophagia 976|Bacteroidetes C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B DYD2_k127_4783626_36 388413.ALPR1_20523 2.368e-22 98.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,47S5V@768503|Cytophagia 976|Bacteroidetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C DYD2_k127_4783626_16 926549.KI421517_gene2270 3.765e-110 366.0 COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,47JYV@768503|Cytophagia 976|Bacteroidetes C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A DYD2_k127_4783626_25 1237149.C900_04598 6.982e-57 201.0 COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,47RT9@768503|Cytophagia 976|Bacteroidetes M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin DYD2_k127_4783626_18 1237149.C900_04597 7.302e-100 333.0 COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,47PPP@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 nlpD_1 - - - - - - - - - - - Peptidase_M23 DYD2_k127_4783626_7 1237149.C900_04596 8.967e-228 732.0 COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,47K0V@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeats sprE - - - - - - - - - - - TPR_16,TPR_6,TPR_8 DYD2_k127_4783626_1 1237149.C900_04595 0.0 1080.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47K6R@768503|Cytophagia 976|Bacteroidetes M Penicillin binding protein transpeptidase pbpB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase DYD2_k127_4783626_22 1237149.C900_04594 4.337e-70 240.0 COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,47JXP@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N DYD2_k127_4786518_5 1123073.KB899241_gene3087 1.625e-184 584.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,1X4F1@135614|Xanthomonadales 135614|Xanthomonadales E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N DYD2_k127_4786518_3 1121904.ARBP01000004_gene1111 3.304e-231 730.0 COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,47JQH@768503|Cytophagia 976|Bacteroidetes G Alpha amylase, catalytic domain amyA2 - - - - - - - - - - - Alpha-amylase,tRNA_SAD DYD2_k127_4786518_4 1237149.C900_02045 1.668e-230 730.0 COG0366@1|root,COG0366@2|Bacteria,4NFMM@976|Bacteroidetes,47KUA@768503|Cytophagia 976|Bacteroidetes G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 DYD2_k127_4786518_0 865937.Gilli_0573 0.0 1236.0 COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,4NFE4@976|Bacteroidetes,1IJPX@117743|Flavobacteriia 976|Bacteroidetes G Alpha-amylase domain - - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C DYD2_k127_4786518_1 1123234.AUKI01000023_gene1954 1.783e-299 930.0 COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,1HXCC@117743|Flavobacteriia 976|Bacteroidetes G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 DYD2_k127_4786518_2 760192.Halhy_4486 1.737e-283 891.0 COG1449@1|root,COG1449@2|Bacteria,4NFKK@976|Bacteroidetes 976|Bacteroidetes G Belongs to the glycosyl hydrolase 57 family - - - - - - - - - - - - DUF3536,Glyco_hydro_57 DYD2_k127_4786518_7 1237149.C900_00618 9.904e-134 433.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,47PAF@768503|Cytophagia 976|Bacteroidetes G ROK family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK DYD2_k127_4786518_6 1237149.C900_00616 1.916e-145 467.0 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,47M49@768503|Cytophagia 976|Bacteroidetes G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK DYD2_k127_4786518_8 2903.EOD11446 1.894e-34 132.0 COG0166@1|root,KOG2446@2759|Eukaryota 2759|Eukaryota G glucose-6-phosphate isomerase activity GPI GO:0001701,GO:0001704,GO:0001707,GO:0001775,GO:0002252,GO:0002262,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002637,GO:0002639,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002791,GO:0002793,GO:0003008,GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005929,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006098,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006739,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006959,GO:0007275,GO:0007369,GO:0007498,GO:0007599,GO:0007610,GO:0007611,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009410,GO:0009435,GO:0009438,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009888,GO:0009892,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010466,GO:0010594,GO:0010595,GO:0010605,GO:0010632,GO:0010634,GO:0010941,GO:0010951,GO:0012505,GO:0014070,GO:0014072,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016192,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0016866,GO:0017144,GO:0018130,GO:0019222,GO:0019242,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019682,GO:0019693,GO:0019752,GO:0019899,GO:0030141,GO:0030162,GO:0030246,GO:0030334,GO:0030335,GO:0031012,GO:0031090,GO:0031253,GO:0031323,GO:0031324,GO:0031410,GO:0031625,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032355,GO:0032501,GO:0032502,GO:0032570,GO:0032787,GO:0032879,GO:0032880,GO:0032940,GO:0033500,GO:0033574,GO:0033993,GO:0034101,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034774,GO:0035902,GO:0035994,GO:0036094,GO:0036230,GO:0040012,GO:0040017,GO:0042119,GO:0042180,GO:0042181,GO:0042221,GO:0042493,GO:0042592,GO:0042593,GO:0042866,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043278,GO:0043279,GO:0043281,GO:0043299,GO:0043312,GO:0043436,GO:0043523,GO:0043524,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044389,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0045861,GO:0046031,GO:0046034,GO:0046184,GO:0046185,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046686,GO:0046700,GO:0046903,GO:0046939,GO:0048029,GO:0048332,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048598,GO:0048646,GO:0048729,GO:0048856,GO:0048872,GO:0048878,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050877,GO:0050878,GO:0050890,GO:0050896,GO:0051023,GO:0051024,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051156,GO:0051171,GO:0051172,GO:0051179,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060170,GO:0060205,GO:0060255,GO:0060359,GO:0060548,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0062039,GO:0062040,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0071704,GO:0071944,GO:0072330,GO:0072347,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097458,GO:0097708,GO:0098588,GO:0098590,GO:0099503,GO:0101002,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901214,GO:1901215,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901654,GO:1901698,GO:1901700,GO:1903530,GO:1903532,GO:1904813,GO:1904951,GO:2000116,GO:2000117,GO:2000145,GO:2000147 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI DYD2_k127_4794389_23 1123248.KB893331_gene3762 4.964e-70 242.0 28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,1ISKT@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4918) - - - - - - - - - - - - DUF4918 DYD2_k127_4794389_0 1237149.C900_01563 0.0 1066.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_4794389_4 1124780.ANNU01000019_gene1723 2.678e-204 654.0 COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,47MJ9@768503|Cytophagia 976|Bacteroidetes L PFAM Type III restriction enzyme, res subunit - - - - - - - - - - - - AAA_11,AAA_12 DYD2_k127_4794389_5 1239962.C943_01182 7.125e-200 637.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia 976|Bacteroidetes J Amidase - - - - - - - - - - - - Amidase DYD2_k127_4794389_29 926559.JoomaDRAFT_2136 7.419e-53 191.0 COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1I2EF@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 DYD2_k127_4794389_15 1348114.OM33_13445 4.279e-119 396.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,2Q0XD@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S COG1473 Metal-dependent amidase aminoacylase carboxypeptidase hipO - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 DYD2_k127_4794389_38 485917.Phep_3467 6.975e-14 78.0 2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1ITQK@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4794389_31 700598.Niako_5254 3.37e-37 144.0 COG2940@1|root,COG2940@2|Bacteria,4NQ3D@976|Bacteroidetes 976|Bacteroidetes S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - ko:K07117 - - - - ko00000 - - - SET DYD2_k127_4794389_33 1267211.KI669560_gene194 6.77e-33 129.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,1IYVW@117747|Sphingobacteriia 976|Bacteroidetes L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD2_k127_4794389_27 1237149.C900_01882 7.459e-62 229.0 COG2885@1|root,COG2885@2|Bacteria 2|Bacteria M chlorophyll binding - - - - - - - - - - - - OmpA DYD2_k127_4794389_17 1124780.ANNU01000021_gene3030 4.331e-96 324.0 COG1215@1|root,COG1215@2|Bacteria,4PKBU@976|Bacteroidetes,47MX1@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_trans_2_3,Glycos_transf_2 DYD2_k127_4794389_6 1123057.P872_14565 2.795e-198 630.0 COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,47JSS@768503|Cytophagia 976|Bacteroidetes E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD2_k127_4794389_7 1237149.C900_03053 1.575e-190 599.0 COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,47NZ3@768503|Cytophagia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 DYD2_k127_4794389_9 1237149.C900_03052 6.663e-164 526.0 COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,47N0I@768503|Cytophagia 976|Bacteroidetes M PFAM peptidase M28 - - - - - - - - - - - - PD40,PDZ_2,Peptidase_M28 DYD2_k127_4794389_8 1237149.C900_01252 6.557e-183 577.0 COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,47KSQ@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 DYD2_k127_4794389_37 1237149.C900_01251 3.165e-16 87.0 COG3170@1|root,COG3170@2|Bacteria,4PNNG@976|Bacteroidetes,47SUJ@768503|Cytophagia 976|Bacteroidetes NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - DYD2_k127_4794389_11 926559.JoomaDRAFT_1633 1.477e-134 437.0 COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,1HX1B@117743|Flavobacteriia 976|Bacteroidetes S COGs COG4299 conserved - - - - - - - - - - - - DUF1624,DUF5009 DYD2_k127_4794389_28 1089547.KB913014_gene4929 3.701e-56 203.0 2DBWZ@1|root,2ZBKJ@2|Bacteria,4NMS8@976|Bacteroidetes,47PF3@768503|Cytophagia 976|Bacteroidetes S HmuY protein - - - - - - - - - - - - HmuY DYD2_k127_4794389_2 1089547.KB913014_gene4931 1.417e-218 699.0 COG1629@1|root,COG4771@2|Bacteria,4NET0@976|Bacteroidetes,47KWB@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor hmuR - - ko:K16089 - - - - ko00000,ko02000 1.B.14.1,1.B.14.10 - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_4794389_22 1492737.FEM08_00090 4.933e-71 250.0 COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,1HXZM@117743|Flavobacteriia,2NSWQ@237|Flavobacterium 976|Bacteroidetes K AraC family transcriptional regulator - - - - - - - - - - - - HTH_18 DYD2_k127_4794389_3 1434325.AZQN01000003_gene2492 9.234e-216 679.0 COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,47M2I@768503|Cytophagia 976|Bacteroidetes S Bacterial protein of unknown function (DUF853) - - - ko:K06915 - - - - ko00000 - - - DUF853 DYD2_k127_4794389_30 700598.Niako_1585 5.717e-45 168.0 COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes 976|Bacteroidetes K (GNAT) family - - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 DYD2_k127_4794389_19 1288963.ADIS_0583 7.954e-88 299.0 COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,47NWC@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF3078) - - - - - - - - - - - - DUF3078 DYD2_k127_4794389_24 1237149.C900_03791 2.092e-67 231.0 COG2199@1|root,COG3706@2|Bacteria,4PKDN@976|Bacteroidetes,47QRP@768503|Cytophagia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD2_k127_4794389_12 1237149.C900_03789 5.416e-134 444.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NHG0@976|Bacteroidetes,47JZ1@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD2_k127_4794389_18 1237149.C900_03788 2.156e-88 295.0 COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia 976|Bacteroidetes S PFAM O-methyltransferase mdmC - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 DYD2_k127_4794389_10 1237149.C900_03787 1.491e-160 515.0 COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,47JFQ@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C DYD2_k127_4794389_14 1237149.C900_03785 4.334e-123 400.0 COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,47K9N@768503|Cytophagia 976|Bacteroidetes F PFAM Phosphorylase superfamily udp - 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 - - - PNP_UDP_1 DYD2_k127_4794389_20 929703.KE386491_gene3040 9.933e-76 259.0 COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,47PJQ@768503|Cytophagia 976|Bacteroidetes S sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family - - - - - - - - - - - - Hexapep DYD2_k127_4794389_25 1237149.C900_03783 7.954e-67 244.0 28ICP@1|root,32QUE@2|Bacteria,4NR8Q@976|Bacteroidetes,47QZP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4794389_13 1237149.C900_03782 1.225e-133 438.0 28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,47KPJ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2851) - - - - - - - - - - - - DUF2851 DYD2_k127_4794389_16 866536.Belba_1524 3.02e-117 382.0 COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,47JHC@768503|Cytophagia 976|Bacteroidetes F Orotidine 5''-phosphate decarboxylase pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase DYD2_k127_4794389_21 1237149.C900_03780 6.291e-75 257.0 COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,47PRT@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane lipoprotein carrier protein LolA lolA - - ko:K03634 - - - - ko00000 - - - LolA,LolA_2 DYD2_k127_4794389_1 880070.Cycma_2018 4.145e-315 983.0 COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,47JI0@768503|Cytophagia 976|Bacteroidetes D DNA segregation ATPase FtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma DYD2_k127_4794389_26 1341181.FLJC2902T_15110 1.132e-64 253.0 COG3386@1|root,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,1IKDI@117743|Flavobacteriia,2P0DY@237|Flavobacterium 976|Bacteroidetes G Domain of unknown function (DUF5122) beta-propeller - - - - - - - - - - - - DUF5122 DYD2_k127_4794389_34 153721.MYP_1137 7.292e-32 146.0 COG3291@1|root,COG4935@1|root,COG5644@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5644@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia 976|Bacteroidetes M domain protein - - - - - - - - - - - - CHU_C,PKD DYD2_k127_4794389_36 1127692.HMPREF9075_00152 2.706e-16 94.0 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - - - - - - - - - - BACON,Beta_helix,Big_2,CHU_C,DUF11,Flg_new,SLH DYD2_k127_4794389_32 1237149.C900_03778 1.616e-34 134.0 COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,47KYQ@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh DYD2_k127_4795893_0 1237149.C900_01570 7.86e-284 883.0 COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia 976|Bacteroidetes L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt DYD2_k127_4795893_2 1237149.C900_01571 3.368e-88 296.0 COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,47KMH@768503|Cytophagia 976|Bacteroidetes K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 DYD2_k127_4795893_5 1121285.AUFK01000013_gene2356 1.301e-18 88.0 COG2827@1|root,COG2827@2|Bacteria,4NSI7@976|Bacteroidetes,1I49F@117743|Flavobacteriia,3ZSEG@59732|Chryseobacterium 976|Bacteroidetes L Excinuclease ABC subunit C - - - - - - - - - - - - GIY-YIG DYD2_k127_4795893_6 1216967.L100_13100 2.746e-06 49.0 COG2827@1|root,COG2827@2|Bacteria,4NTHH@976|Bacteroidetes,1I467@117743|Flavobacteriia 976|Bacteroidetes L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD2_k127_4795893_1 1123508.JH636442_gene4074 4.739e-158 505.0 COG2055@1|root,COG2055@2|Bacteria,2J36Z@203682|Planctomycetes 203682|Planctomycetes C Malate/L-lactate dehydrogenase - - - - - - - - - - - - Ldh_2 DYD2_k127_4795893_4 1237149.C900_01572 2.749e-44 168.0 COG0526@1|root,COG0526@2|Bacteria,4NI00@976|Bacteroidetes,47QR6@768503|Cytophagia 976|Bacteroidetes CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin DYD2_k127_4803383_19 153721.MYP_2837 2.292e-58 204.0 COG3832@1|root,COG3832@2|Bacteria,4PKNU@976|Bacteroidetes,47QK4@768503|Cytophagia 976|Bacteroidetes S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD2_k127_4803383_11 926559.JoomaDRAFT_0554 5.775e-125 404.0 COG3384@1|root,COG3384@2|Bacteria,4NFGT@976|Bacteroidetes,1HX1P@117743|Flavobacteriia 976|Bacteroidetes S in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine - - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB DYD2_k127_4803383_16 1338011.BD94_2078 2.392e-88 301.0 COG2855@1|root,COG2855@2|Bacteria,4NES6@976|Bacteroidetes,1HYZF@117743|Flavobacteriia,34Q2S@308865|Elizabethkingia 976|Bacteroidetes S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 DYD2_k127_4803383_13 1460635.JCM19038_3236 2.924e-115 383.0 COG3949@1|root,COG3949@2|Bacteria,1U46Z@1239|Firmicutes,4I1HS@91061|Bacilli 91061|Bacilli S Membrane - - - - - - - - - - - - - DYD2_k127_4803383_8 1392498.JQLH01000001_gene2924 1.44e-158 511.0 COG0624@1|root,COG0624@2|Bacteria,4NJN0@976|Bacteroidetes,1I0Y3@117743|Flavobacteriia,2PI95@252356|Maribacter 976|Bacteroidetes E Peptidase family M28 - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD2_k127_4803383_0 1237149.C900_00745 0.0 1103.0 COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,47KBD@768503|Cytophagia 976|Bacteroidetes M AsmA-like C-terminal region - - - - - - - - - - - - AsmA,AsmA_2 DYD2_k127_4803383_24 1124780.ANNU01000078_gene775 7.107e-25 113.0 2ETG7@1|root,338QK@2|Bacteria,4NW0M@976|Bacteroidetes,47X76@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4803383_21 1237149.C900_00748 7.453e-53 195.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2 DYD2_k127_4803383_1 1237149.C900_00749 5.367e-285 889.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40 DYD2_k127_4803383_2 1237149.C900_00750 4.648e-279 876.0 COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,47QDC@768503|Cytophagia 976|Bacteroidetes M Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin DYD2_k127_4803383_9 1237149.C900_00751 3.279e-154 498.0 COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,47MV0@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD2_k127_4803383_3 1237149.C900_00753 4.611e-278 870.0 COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,47JTC@768503|Cytophagia 976|Bacteroidetes CO Cytochrome c biogenesis protein transmembrane region dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 DYD2_k127_4803383_6 1237149.C900_00754 2.264e-229 716.0 COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase family M20 M25 M40 dapE - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD2_k127_4803383_4 1408813.AYMG01000003_gene2872 3.517e-262 812.0 COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,1IPCY@117747|Sphingobacteriia 976|Bacteroidetes C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 DYD2_k127_4803383_18 1237149.C900_04546 2.89e-65 229.0 2DPU6@1|root,333E2@2|Bacteria,4NW9K@976|Bacteroidetes,47RVJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4803383_7 153721.MYP_4405 4.305e-211 669.0 COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia 976|Bacteroidetes L single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD2_k127_4803383_12 1237149.C900_04543 1.413e-124 402.0 COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,47KI2@768503|Cytophagia 976|Bacteroidetes S ABC transporter lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C DYD2_k127_4803383_5 1237149.C900_04542 9.831e-256 796.0 COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,47KAH@768503|Cytophagia 976|Bacteroidetes IQ PFAM GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 DYD2_k127_4803383_17 1237149.C900_03186 2.565e-73 252.0 COG0526@1|root,COG0526@2|Bacteria,4PKPR@976|Bacteroidetes,47PBI@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA DYD2_k127_4803383_23 1237149.C900_03187 3.316e-45 169.0 COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,47RGU@768503|Cytophagia 976|Bacteroidetes CO Thioredoxin trxC - - - - - - - - - - - AhpC-TSA,Thioredoxin,Thioredoxin_8 DYD2_k127_4803383_10 153721.MYP_4401 5.12e-139 448.0 COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,47MJV@768503|Cytophagia 976|Bacteroidetes S Nitronate monooxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO DYD2_k127_4803383_22 1237149.C900_03190 3.17e-48 176.0 COG0346@1|root,COG0346@2|Bacteria,4NRSZ@976|Bacteroidetes,47QSC@768503|Cytophagia 976|Bacteroidetes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD2_k127_4803383_15 1237149.C900_03193 5.056e-98 329.0 COG2017@1|root,COG2017@2|Bacteria,4NE32@976|Bacteroidetes,47KZH@768503|Cytophagia 976|Bacteroidetes G converts alpha-aldose to the beta-anomer - - - - - - - - - - - - - DYD2_k127_4803383_14 1237149.C900_03194 1.092e-107 353.0 COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD2_k127_48354_6 1120965.AUBV01000008_gene2003 2.784e-86 289.0 COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,47JZK@768503|Cytophagia 976|Bacteroidetes L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 DYD2_k127_48354_11 1124780.ANNU01000042_gene620 2.728e-36 139.0 COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,47R8K@768503|Cytophagia 976|Bacteroidetes S PFAM ATP-dependent Clp protease adaptor protein ClpS clpS - - ko:K06891 - - - - ko00000 - - - ClpS DYD2_k127_48354_1 153721.MYP_47 1.254e-187 597.0 COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF DYD2_k127_48354_10 1267211.KI669560_gene85 8.333e-41 153.0 COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1IT8P@117747|Sphingobacteriia 976|Bacteroidetes L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain ogt - 2.1.1.63 ko:K00567,ko:K07443 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 DYD2_k127_48354_2 1237149.C900_00543 1.714e-153 499.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - CHU_C,DUF285,LRR_5,PKD,Peptidase_M43,fn3 DYD2_k127_48354_4 1237149.C900_03873 1.638e-108 361.0 COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,47KA8@768503|Cytophagia 976|Bacteroidetes S TIGRFAM YihY family protein (not ribonuclease BN) yfkH - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB DYD2_k127_48354_8 1237149.C900_03872 6.36e-55 195.0 COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,47Q99@768503|Cytophagia 976|Bacteroidetes S TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family ybgC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 DYD2_k127_48354_3 1237149.C900_03871 1.327e-139 452.0 COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,47J93@768503|Cytophagia 976|Bacteroidetes S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG DYD2_k127_48354_7 1124780.ANNU01000035_gene282 7.91e-80 271.0 COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,47KWK@768503|Cytophagia 976|Bacteroidetes J Belongs to the SUA5 family yciO - - - - - - - - - - - Sua5_yciO_yrdC DYD2_k127_48354_9 1237149.C900_03869 1.87e-54 198.0 COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,47Q4T@768503|Cytophagia 976|Bacteroidetes C PFAM WbqC-like protein family - - - - - - - - - - - - WbqC DYD2_k127_48354_0 1124780.ANNU01000035_gene279 0.0 1407.0 COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,47JFM@768503|Cytophagia 976|Bacteroidetes O Belongs to the ClpA ClpB family clpC - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR DYD2_k127_48354_5 1237149.C900_03865 7.172e-107 359.0 COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,47JA7@768503|Cytophagia 976|Bacteroidetes S oxidoreductase activity - - - - - - - - - - - - - DYD2_k127_4857007_0 1121104.AQXH01000003_gene342 1.25e-154 511.0 COG4206@1|root,COG4206@2|Bacteria,4NHH8@976|Bacteroidetes 976|Bacteroidetes H TonB-dependent receptor btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec DYD2_k127_4857007_2 376686.Fjoh_0084 6.391e-28 116.0 2EAY8@1|root,334Z8@2|Bacteria,4NWBD@976|Bacteroidetes,1I76B@117743|Flavobacteriia,2NWK6@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4857007_1 1124780.ANNU01000008_gene2722 2.773e-118 389.0 COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,47M9T@768503|Cytophagia 976|Bacteroidetes E TIGRFAM LAO AO transport system ATPase argK - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK DYD2_k127_4901750_1 761193.Runsl_0848 1.859e-165 528.0 COG0665@1|root,COG0665@2|Bacteria,4NKQK@976|Bacteroidetes,47Q2W@768503|Cytophagia 976|Bacteroidetes E FAD dependent oxidoreductase - - - - - - - - - - - - DAO DYD2_k127_4901750_0 313603.FB2170_01836 0.0 1403.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia,2PGS6@252356|Maribacter 976|Bacteroidetes M Tricorn protease C1 domain - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ DYD2_k127_4901750_7 1131812.JQMS01000001_gene1857 1.983e-42 159.0 2BUJ8@1|root,32PVN@2|Bacteria,4NQPQ@976|Bacteroidetes,1I2W2@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4901750_11 1408473.JHXO01000011_gene2983 5.694e-10 61.0 COG3070@1|root,COG3070@2|Bacteria,4NQWP@976|Bacteroidetes,2FTFF@200643|Bacteroidia 976|Bacteroidetes K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N DYD2_k127_4901750_6 700598.Niako_4639 8.265e-69 242.0 arCOG06802@1|root,2ZBBG@2|Bacteria,4P1GR@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4901750_2 760192.Halhy_5428 1.107e-133 435.0 COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1IQ64@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Cys Met metabolism PLP-dependent enzyme metC - 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP DYD2_k127_4901750_3 388413.ALPR1_02035 6.193e-115 380.0 COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,47KAR@768503|Cytophagia 976|Bacteroidetes G Converts alpha-aldose to the beta-anomer mro - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim DYD2_k127_4901750_4 1120965.AUBV01000003_gene419 3.726e-109 358.0 2ACD4@1|root,311YD@2|Bacteria,4NPIQ@976|Bacteroidetes,47UU4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4901750_9 1131730.BAVI_00750 7.45e-31 123.0 COG3708@1|root,COG3708@2|Bacteria,1VJT1@1239|Firmicutes,4HREN@91061|Bacilli,1ZRAV@1386|Bacillus 91061|Bacilli K Putative zinc ribbon domain - - - - - - - - - - - - Zn_ribbon_2 DYD2_k127_4901750_5 1178825.ALIH01000004_gene2863 7.435e-80 272.0 COG3485@1|root,COG3485@2|Bacteria,4NEZ1@976|Bacteroidetes,1I01Q@117743|Flavobacteriia 976|Bacteroidetes Q Dioxygenase - - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C DYD2_k127_4901750_10 326427.Cagg_2132 7.496e-28 128.0 COG3174@1|root,COG3174@2|Bacteria,2G8K3@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC DYD2_k127_4901750_8 313595.P700755_001306 7.018e-41 154.0 COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,1HZF1@117743|Flavobacteriia 976|Bacteroidetes G Alpha-amylase domain malL - 3.2.1.1,3.2.1.10,5.4.99.16 ko:K01182,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262 RC00028,RC00059,RC00077,RC00451,RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C DYD2_k127_4902085_4 1047013.AQSP01000106_gene1768 1.665e-30 130.0 COG0405@1|root,COG0405@2|Bacteria,2NP8H@2323|unclassified Bacteria 2|Bacteria E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD2_k127_4902085_1 580340.Tlie_1160 3.59e-157 505.0 COG0520@1|root,COG0520@2|Bacteria,3TAAX@508458|Synergistetes 508458|Synergistetes E TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - - - - - - - - - - Aminotran_5 DYD2_k127_4902085_0 1239962.C943_00110 6.792e-248 777.0 COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47MDS@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran,Peptidase_C39 DYD2_k127_4902085_2 1121875.KB907550_gene729 1.189e-51 194.0 2ET8I@1|root,33KSM@2|Bacteria,4NZEX@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4902085_3 1121875.KB907550_gene730 4.833e-34 136.0 COG1695@1|root,COG1695@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated padR - - - - - - - - - - - DUF2703,PadR,Vir_act_alpha_C DYD2_k127_4919357_1 1121012.AUKX01000012_gene2185 5.71e-212 676.0 COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia,23HWG@178469|Arenibacter 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,TPR_12,TPR_8 DYD2_k127_4919357_9 1121875.KB907547_gene3439 2.654e-14 79.0 2ENSM@1|root,33GDT@2|Bacteria,4NZJZ@976|Bacteroidetes,1I6A0@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4919357_0 1250232.JQNJ01000001_gene1504 0.0 1629.0 COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia 976|Bacteroidetes G alpha-L-arabinofuranosidase - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_4919357_4 1121904.ARBP01000009_gene4355 7.745e-83 291.0 COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,47JVE@768503|Cytophagia 976|Bacteroidetes S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk DYD2_k127_4919357_10 1293047.CBMA010000024_gene1270 1.467e-09 70.0 COG2309@1|root,arCOG01890@2157|Archaea,2XU28@28890|Euryarchaeota,23SUF@183963|Halobacteria 183963|Halobacteria E Leucyl aminopeptidase (Aminopeptidase t) pepB1 - - - - - - - - - - - Peptidase_M29 DYD2_k127_4919357_7 234267.Acid_6501 2.439e-43 169.0 COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria 57723|Acidobacteria M Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD2_k127_4919357_3 1121957.ATVL01000010_gene392 4.992e-149 482.0 COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,47KTS@768503|Cytophagia 976|Bacteroidetes O Zn-dependent protease with chaperone function - - 3.4.24.84 ko:K03799,ko:K06013 ko00900,ko01130,map00900,map01130 M00743 R09845 RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N DYD2_k127_4919357_2 1499967.BAYZ01000095_gene4135 6.32e-160 514.0 COG0006@1|root,COG0006@2|Bacteria 2|Bacteria E proline dipeptidase activity pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 DYD2_k127_4919357_5 1237149.C900_04890 7.022e-79 278.0 COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,47JWS@768503|Cytophagia 976|Bacteroidetes P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA DYD2_k127_4919357_6 1120965.AUBV01000007_gene2489 6.9e-75 260.0 COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 DYD2_k127_4921314_12 1227739.Hsw_2924 2.836e-28 118.0 COG0406@1|root,COG0406@2|Bacteria,4NFX5@976|Bacteroidetes,47JSV@768503|Cytophagia 976|Bacteroidetes G phosphoglycerate mutase family gpm - - - - - - - - - - - His_Phos_1 DYD2_k127_4921314_8 1237149.C900_04752 2.417e-79 284.0 COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,47JRE@768503|Cytophagia 976|Bacteroidetes S TPR repeat-containing protein - - - - - - - - - - - - TPR_12,TPR_7,TPR_8 DYD2_k127_4921314_4 1237149.C900_04751 2.138e-107 353.0 COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,47JBK@768503|Cytophagia 976|Bacteroidetes S Zn-ribbon protein, possibly nucleic acid-binding - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 DYD2_k127_4921314_2 1237149.C900_04750 2.286e-149 481.0 COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,47JGH@768503|Cytophagia 976|Bacteroidetes S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO - - - - - - - - - - - NIF3 DYD2_k127_4921314_5 153721.MYP_534 1.288e-102 344.0 COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,47M44@768503|Cytophagia 976|Bacteroidetes M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK DYD2_k127_4921314_3 1237149.C900_04748 7.437e-140 467.0 COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,47JRI@768503|Cytophagia 976|Bacteroidetes H Putative porin - - - - - - - - - - - - Porin_10 DYD2_k127_4921314_6 1237149.C900_04747 1.976e-90 303.0 COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,47P6J@768503|Cytophagia 976|Bacteroidetes FJ Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE DYD2_k127_4921314_0 1237149.C900_04746 3.526e-224 699.0 2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,47MEQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_4921314_1 1237149.C900_04745 8.272e-172 547.0 COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,47KYR@768503|Cytophagia 976|Bacteroidetes V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_4921314_7 1124780.ANNU01000010_gene3595 1.045e-87 299.0 COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,47VAC@768503|Cytophagia 976|Bacteroidetes G pfkB family carbohydrate kinase ydjH_1 - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB DYD2_k127_4921314_9 1168289.AJKI01000041_gene3331 8.788e-72 248.0 COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes 976|Bacteroidetes E COG2755 Lysophospholipase L1 and related - - - - - - - - - - - - Lipase_GDSL_2 DYD2_k127_4921314_11 1122176.KB903531_gene3085 1.459e-57 206.0 COG4430@1|root,COG4430@2|Bacteria,4NKNI@976|Bacteroidetes,1ITNC@117747|Sphingobacteriia 976|Bacteroidetes S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1801,OmdA DYD2_k127_4921314_13 1121904.ARBP01000045_gene1842 2.069e-21 106.0 COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47TVA@768503|Cytophagia 976|Bacteroidetes T helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_8,Y_Y_Y DYD2_k127_4921314_10 1121875.KB907549_gene1707 2.832e-61 223.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 DYD2_k127_4940616_1 1237149.C900_00286 9.753e-240 779.0 COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia 976|Bacteroidetes L Belongs to the helicase family. UvrD subfamily addA - - - - - - - - - - - Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C DYD2_k127_4940616_0 1237149.C900_04407 2.561e-263 831.0 COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia 976|Bacteroidetes S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin DYD2_k127_4940616_4 1237149.C900_04906 2.115e-33 130.0 2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,47VEE@768503|Cytophagia 976|Bacteroidetes S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP DYD2_k127_4940616_2 700598.Niako_6457 6.97e-202 642.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1IR8Z@117747|Sphingobacteriia 976|Bacteroidetes Q PFAM D-aminoacylase, C-terminal region - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 DYD2_k127_4940616_3 700598.Niako_1535 1.322e-57 205.0 28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,1ISKT@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4918) - - - - - - - - - - - - DUF4918 DYD2_k127_5026499_1 1279009.ADICEAN_02856 4.735e-239 769.0 COG3857@1|root,COG3857@2|Bacteria,4PKEH@976|Bacteroidetes,47YDH@768503|Cytophagia 976|Bacteroidetes L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - Exonuc_V_gamma,PDDEXK_1 DYD2_k127_5026499_0 1131812.JQMS01000001_gene40 0.0 1081.0 COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium 976|Bacteroidetes P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD2_k127_5026499_2 504487.JCM19302_2912 5.464e-42 159.0 2C1XD@1|root,340CH@2|Bacteria,4P45P@976|Bacteroidetes 976|Bacteroidetes S Putative lumazine-binding - - - - - - - - - - - - Lumazine_bd_2 DYD2_k127_5052145_4 760192.Halhy_3095 2.554e-138 452.0 COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1IQ0A@117747|Sphingobacteriia 976|Bacteroidetes S PFAM CBS domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 DYD2_k127_5052145_10 865937.Gilli_0829 4.456e-38 146.0 2BZ54@1|root,3342Z@2|Bacteria,4NVGG@976|Bacteroidetes,1I59B@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5052145_3 865937.Gilli_0828 2.766e-153 487.0 28HDX@1|root,2Z7QG@2|Bacteria,4NFID@976|Bacteroidetes,1HZD2@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5052145_7 1317122.ATO12_13665 2.887e-107 357.0 COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1HZK9@117743|Flavobacteriia,2YKHN@290174|Aquimarina 976|Bacteroidetes E Homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - Homoserine_dh,NAD_binding_3 DYD2_k127_5052145_1 1288963.ADIS_1925 1.334e-192 608.0 COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD2_k127_5052145_6 761193.Runsl_2216 1.059e-110 363.0 COG2520@1|root,COG2520@2|Bacteria,4NNG5@976|Bacteroidetes,47PX7@768503|Cytophagia 976|Bacteroidetes J Methyltransferase FkbM domain - - - - - - - - - - - - Methyltransf_21 DYD2_k127_5052145_12 1131812.JQMS01000001_gene765 8.529e-19 92.0 2BK9M@1|root,32EPT@2|Bacteria,4NQGA@976|Bacteroidetes,1I2SP@117743|Flavobacteriia,2NWJ8@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5052145_5 929562.Emtol_1230 4.631e-116 380.0 COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,47M5Z@768503|Cytophagia 976|Bacteroidetes S Putative esterase - - - - - - - - - - - - Esterase DYD2_k127_5052145_0 1279009.ADICEAN_02559 5.608e-193 612.0 COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,47JUJ@768503|Cytophagia 976|Bacteroidetes G Glycogen debranching enzyme, glucanotransferase domain amyB - - - - - - - - - - - Alpha-amylase,Alpha-amylase_C,Malt_amylase_C DYD2_k127_5052145_11 1121875.KB907546_gene2504 4.761e-27 115.0 COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,1I2DE@117743|Flavobacteriia 976|Bacteroidetes S Calcineurin-like phosphoesterase - - - - - - - - - - - - Fn3_assoc,Metallophos,PA14 DYD2_k127_5052145_8 1121875.KB907546_gene2504 9.961e-65 228.0 COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,1I2DE@117743|Flavobacteriia 976|Bacteroidetes S Calcineurin-like phosphoesterase - - - - - - - - - - - - Fn3_assoc,Metallophos,PA14 DYD2_k127_5052145_9 313596.RB2501_12217 3.542e-55 196.0 COG0346@1|root,COG0346@2|Bacteria,4P85Q@976|Bacteroidetes 976|Bacteroidetes C Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase DYD2_k127_5052145_2 1237149.C900_04121 3.297e-177 572.0 COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,47JGS@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug DYD2_k127_5056613_6 926556.Echvi_0656 1.845e-25 111.0 COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,47KI4@768503|Cytophagia 976|Bacteroidetes G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase DYD2_k127_5056613_3 1237149.C900_02727 1.971e-82 279.0 COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,47PRP@768503|Cytophagia 976|Bacteroidetes S PFAM CBS domain - - - - - - - - - - - - CBS DYD2_k127_5056613_1 1279009.ADICEAN_01090 3.204e-126 407.0 COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,47KEX@768503|Cytophagia 976|Bacteroidetes I alpha/beta hydrolase fold pcbD - - - - - - - - - - - Abhydrolase_1 DYD2_k127_5056613_5 1237149.C900_02730 1.693e-38 150.0 COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,47S9N@768503|Cytophagia 976|Bacteroidetes S PFAM Colicin V production protein cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V DYD2_k127_5056613_4 643867.Ftrac_1783 5.886e-48 176.0 COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,47QJ2@768503|Cytophagia 976|Bacteroidetes S PFAM Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY DYD2_k127_5056613_2 1120968.AUBX01000011_gene3076 1.713e-107 352.0 COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,47K7U@768503|Cytophagia 976|Bacteroidetes H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ DYD2_k127_5056613_0 313603.FB2170_02290 8.697e-277 860.0 COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,1I15X@117743|Flavobacteriia,2PGC0@252356|Maribacter 976|Bacteroidetes P Putative esterase - - - - - - - - - - - - Esterase DYD2_k127_5109209_14 1123276.KB893313_gene3910 1.032e-06 53.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47MNC@768503|Cytophagia 976|Bacteroidetes C Aldehyde dehydrogenase family mmsA - 1.2.1.18,1.2.1.27 ko:K00140,ko:K22187 ko00040,ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00040,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935,R11768 RC00004,RC00080,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_5109209_4 566466.NOR53_670 3.061e-148 488.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1J7SK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD2_k127_5109209_15 1121104.AQXH01000004_gene59 6.928e-06 55.0 COG4430@1|root,COG4430@2|Bacteria,4NU24@976|Bacteroidetes 976|Bacteroidetes S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1905,OmdA DYD2_k127_5109209_0 761193.Runsl_4234 0.0 1478.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_5109209_8 1197477.IA57_05695 1.21e-75 258.0 COG1573@1|root,COG1573@2|Bacteria,4NG84@976|Bacteroidetes,1HXRH@117743|Flavobacteriia 976|Bacteroidetes L Uracil DNA glycosylase superfamily - - - - - - - - - - - - UDG DYD2_k127_5109209_3 760192.Halhy_0262 1.125e-181 582.0 COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,1IPCS@117747|Sphingobacteriia 976|Bacteroidetes G Glycosyl hydrolase family 32 - - 3.2.1.80 ko:K03332 ko00051,map00051 - R00879 - ko00000,ko00001,ko01000 - - - Glyco_hydro_32C,Glyco_hydro_32N DYD2_k127_5109209_2 1121875.KB907550_gene856 1.598e-207 653.0 COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia 976|Bacteroidetes EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - - - - - - - - - - Sugar_tr DYD2_k127_5109209_11 768706.Desor_2156 2.27e-17 85.0 2CF4I@1|root,32S18@2|Bacteria,1VCJC@1239|Firmicutes,24PWM@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD2_k127_5109209_7 398720.MED217_07791 1.441e-117 385.0 COG4989@1|root,COG4989@2|Bacteria,4NENV@976|Bacteroidetes,1HY8B@117743|Flavobacteriia,2XK5T@283735|Leeuwenhoekiella 976|Bacteroidetes S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD2_k127_5109209_13 1128398.Curi_c23590 4.544e-07 55.0 COG4980@1|root,COG4980@2|Bacteria,1VK4M@1239|Firmicutes,25MZT@186801|Clostridia,26CDV@186813|unclassified Clostridiales 186801|Clostridia S YtxH-like protein - - - - - - - - - - - - YtxH DYD2_k127_5109209_9 204669.Acid345_1386 2.013e-37 147.0 2EDAV@1|root,33776@2|Bacteria,3Y8RG@57723|Acidobacteria,2JNHN@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - DYD2_k127_5109209_5 204669.Acid345_1385 6.833e-125 403.0 COG0479@1|root,COG0479@2|Bacteria,3Y70A@57723|Acidobacteria,2JM7N@204432|Acidobacteriia 204432|Acidobacteriia C 2Fe-2S iron-sulfur cluster binding domain - - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 DYD2_k127_5109209_1 204669.Acid345_1384 1.95e-294 912.0 COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia 204432|Acidobacteriia C Fumarate reductase flavoprotein C-term - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD2_k127_5109209_6 1210884.HG799466_gene12570 6.264e-118 383.0 2CEY7@1|root,2Z8CG@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - - DYD2_k127_5109209_12 1424334.W822_07655 5.198e-10 60.0 COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2WFNG@28216|Betaproteobacteria 28216|Betaproteobacteria O PFAM OsmC family protein - - - - - - - - - - - - OsmC DYD2_k127_5109209_10 204669.Acid345_1947 2.192e-29 117.0 COG1764@1|root,COG1764@2|Bacteria,3Y8XQ@57723|Acidobacteria 57723|Acidobacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD2_k127_5118402_5 1408433.JHXV01000005_gene2538 2.492e-114 376.0 COG2070@1|root,COG2070@2|Bacteria,4NFIW@976|Bacteroidetes,1HY76@117743|Flavobacteriia,2PBER@246874|Cryomorphaceae 976|Bacteroidetes S Thiazole biosynthesis protein ThiG - - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO DYD2_k127_5118402_4 255470.cbdbA553 9.146e-123 404.0 COG0436@1|root,COG0436@2|Bacteria,2GAS1@200795|Chloroflexi,34D7A@301297|Dehalococcoidia 301297|Dehalococcoidia E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 DYD2_k127_5118402_9 1382306.JNIM01000001_gene1150 1.43e-29 120.0 COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_4 DYD2_k127_5118402_0 742817.HMPREF9449_02657 2.542e-250 786.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,22WBU@171551|Porphyromonadaceae 976|Bacteroidetes C 2-oxoacid acceptor oxidoreductase, alpha subunit porA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N DYD2_k127_5118402_3 886379.AEWI01000078_gene1974 1.532e-137 445.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,3XJPN@558415|Marinilabiliaceae 976|Bacteroidetes C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain oorB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C DYD2_k127_5118402_6 1121875.KB907547_gene3141 2.998e-85 287.0 COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 DYD2_k127_5118402_8 1121875.KB907547_gene3142 1.328e-48 178.0 COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa DYD2_k127_5118402_1 313603.FB2170_07949 3.321e-193 607.0 COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases DYD2_k127_5118402_2 700598.Niako_7215 1.351e-153 492.0 COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1INP9@117747|Sphingobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD2_k127_5118402_7 1408473.JHXO01000002_gene3884 6.029e-63 219.0 COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,2FQYT@200643|Bacteroidia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 DYD2_k127_5134070_9 1380600.AUYN01000007_gene3361 3.889e-57 206.0 COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia 976|Bacteroidetes D Di-iron-containing protein involved in the repair of iron-sulfur clusters ric - - ko:K07322 - - - - ko00000 - - - Hemerythrin,ScdA_N DYD2_k127_5134070_13 1121904.ARBP01000032_gene2021 2.89e-18 94.0 COG3743@1|root,COG3743@2|Bacteria,4NSZH@976|Bacteroidetes,47PEM@768503|Cytophagia 976|Bacteroidetes S rRNA binding - - - - - - - - - - - - HHH_5 DYD2_k127_5134070_14 700598.Niako_1271 2.045e-08 55.0 COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes,1IPJ1@117747|Sphingobacteriia 976|Bacteroidetes O PFAM AIR synthase related protein, N-terminal domain - - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C DYD2_k127_5134070_10 1408473.JHXO01000006_gene1031 4.202e-57 204.0 COG2210@1|root,COG2210@2|Bacteria,4NNB9@976|Bacteroidetes,2FW6V@200643|Bacteroidia 976|Bacteroidetes S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 DYD2_k127_5134070_12 1408473.JHXO01000006_gene1030 2.23e-33 131.0 COG2920@1|root,COG2920@2|Bacteria,4NSKM@976|Bacteroidetes,2FVZW@200643|Bacteroidia 976|Bacteroidetes P DsrC like protein - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC DYD2_k127_5134070_4 886379.AEWI01000122_gene1875 1.419e-180 573.0 COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,2FT9Y@200643|Bacteroidia 976|Bacteroidetes S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD2_k127_5134070_11 313606.M23134_04780 1.507e-38 147.0 COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,47QGA@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR DYD2_k127_5134070_0 1237149.C900_04654 2.78e-286 906.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_5134070_8 1112217.PPL19_16135 1.053e-64 223.0 COG1607@1|root,COG1607@2|Bacteria,1REI5@1224|Proteobacteria,1S4M2@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Thioesterase HA62_15520 - - - - - - - - - - - 4HBT DYD2_k127_5134070_5 1121904.ARBP01000003_gene6401 2.644e-145 474.0 COG0624@1|root,COG0624@2|Bacteria,4NEHJ@976|Bacteroidetes,47MC5@768503|Cytophagia 976|Bacteroidetes E Peptidase dimerisation domain - - - ko:K13049 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD2_k127_5134070_1 1122176.KB903576_gene4886 7.758e-231 720.0 COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,1J19G@117747|Sphingobacteriia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD2_k127_5134070_2 1237149.C900_03443 3.08e-196 631.0 COG1729@1|root,COG1729@2|Bacteria,4PKMW@976|Bacteroidetes,47JRZ@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6,TPR_8 DYD2_k127_5134070_6 1237149.C900_03442 2.985e-116 394.0 COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,47KXU@768503|Cytophagia 976|Bacteroidetes S Bacterial Ig-like domain - - - - - - - - - - - - Big_5,fn3_3 DYD2_k127_5134070_7 929703.KE386491_gene2923 1.32e-77 269.0 COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,47K52@768503|Cytophagia 976|Bacteroidetes H Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_23 DYD2_k127_5134070_3 1237149.C900_03440 3.582e-186 588.0 COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia 976|Bacteroidetes D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc DYD2_k127_5136417_1 926549.KI421517_gene2412 1.016e-189 602.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_5136417_3 1379270.AUXF01000003_gene3553 5.333e-53 197.0 COG2362@1|root,COG2362@2|Bacteria,1ZUMF@142182|Gemmatimonadetes 142182|Gemmatimonadetes E D-aminopeptidase - - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - - Peptidase_M55 DYD2_k127_5136417_4 760192.Halhy_4488 2.699e-23 110.0 COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1IUAS@117747|Sphingobacteriia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 DYD2_k127_5136417_0 1121904.ARBP01000004_gene1108 0.0 1049.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_5136417_2 313603.FB2170_04350 3.407e-138 445.0 COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HXEI@117743|Flavobacteriia,2PIQ7@252356|Maribacter 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD2_k127_5160239_0 761193.Runsl_3068 0.0 1144.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_5160239_3 1237149.C900_02632 2.466e-31 125.0 COG4095@1|root,COG4095@2|Bacteria 2|Bacteria S Sugar efflux transporter for intercellular exchange - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - MtN3_slv,PQ-loop DYD2_k127_5160239_2 419610.Mext_2378 5.326e-69 239.0 COG0431@1|root,COG0431@2|Bacteria,1MXQ8@1224|Proteobacteria,2TRI5@28211|Alphaproteobacteria,1JRCT@119045|Methylobacteriaceae 28211|Alphaproteobacteria E NADPH-dependent FMN reductase MA20_28735 - - - - - - - - - - - FMN_red DYD2_k127_5160239_1 643867.Ftrac_1601 2.929e-155 499.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,47QVZ@768503|Cytophagia 976|Bacteroidetes O OsmC-like protein - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC DYD2_k127_5160239_4 1121890.AUDO01000007_gene2505 1.974e-29 120.0 COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,1HX9T@117743|Flavobacteriia,2NTRU@237|Flavobacterium 976|Bacteroidetes P Polyphosphate kinase N-terminal domain ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N DYD2_k127_5171007_4 1124780.ANNU01000089_gene313 4.625e-149 480.0 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47KUQ@768503|Cytophagia 976|Bacteroidetes E PFAM Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD2_k127_5171007_6 1237149.C900_03404 5.028e-142 467.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2 DYD2_k127_5171007_9 421531.IX38_18465 6.109e-65 228.0 COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1I1TP@117743|Flavobacteriia,3ZQNN@59732|Chryseobacterium 976|Bacteroidetes L Belongs to the DNA glycosylase MPG family mpg - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco DYD2_k127_5171007_8 643867.Ftrac_0143 1.242e-88 300.0 COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 DYD2_k127_5171007_2 153721.MYP_3076 1.613e-209 665.0 COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47K2R@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family yidK - - - - - - - - - - - SSF DYD2_k127_5171007_0 1237149.C900_04147 1.455e-298 937.0 COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia 976|Bacteroidetes G PFAM GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L DYD2_k127_5171007_1 926549.KI421517_gene1462 1.13e-211 675.0 COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47JCA@768503|Cytophagia 976|Bacteroidetes S ABC transporter yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn DYD2_k127_5171007_12 700598.Niako_2074 1.471e-52 190.0 2DVQJ@1|root,32UZZ@2|Bacteria,4PGTB@976|Bacteroidetes,1IUA6@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5171007_13 1237149.C900_00073 6.094e-48 178.0 COG0457@1|root,COG0457@2|Bacteria 1237149.C900_00073|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD2_k127_5171007_7 1237149.C900_00072 1.97e-115 377.0 COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,47PE5@768503|Cytophagia 976|Bacteroidetes L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku - - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku DYD2_k127_5171007_3 1189612.A33Q_3117 7.282e-172 549.0 COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,47JE8@768503|Cytophagia 976|Bacteroidetes S unusual protein kinase - - - - - - - - - - - - ABC1,APH DYD2_k127_5171007_11 643867.Ftrac_1566 8.194e-60 214.0 28HM7@1|root,2Z7VU@2|Bacteria,4NGV1@976|Bacteroidetes,47PTW@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5171007_10 1123057.P872_13775 8.651e-65 237.0 COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia 976|Bacteroidetes S TPR repeat-containing protein - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 DYD2_k127_5171007_5 1237149.C900_00071 1.273e-143 463.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia 976|Bacteroidetes L DNA polymerase Ligase (LigD) - - - - - - - - - - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N DYD2_k127_5211531_7 1121930.AQXG01000004_gene2972 1.247e-72 248.0 COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,1IW66@117747|Sphingobacteriia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD2_k127_5211531_4 1123248.KB893348_gene343 1.584e-91 310.0 COG0697@1|root,COG0697@2|Bacteria,4NGPQ@976|Bacteroidetes,1IXG8@117747|Sphingobacteriia 976|Bacteroidetes EG EamA-like transporter family - - - - - - - - - - - - EamA DYD2_k127_5211531_8 1237149.C900_03196 2.615e-70 246.0 COG2350@1|root,COG2350@2|Bacteria 2|Bacteria S YCII-related domain - - - - - - - - - - - - YCII DYD2_k127_5211531_9 929562.Emtol_2377 9.466e-54 199.0 COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes,47R0N@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 DYD2_k127_5211531_2 1237149.C900_00782 9.575e-154 490.0 COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,47MQ3@768503|Cytophagia 976|Bacteroidetes O Pyridine nucleotide-disulphide oxidoreductase ypdA - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_3 DYD2_k127_5211531_15 1392490.JHZX01000001_gene2529 0.000683 49.0 295AX@1|root,2ZSP3@2|Bacteria,4P8WU@976|Bacteroidetes,1IB9K@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5211531_6 1237149.C900_05513 1.179e-79 274.0 COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,47K5K@768503|Cytophagia 976|Bacteroidetes G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin DYD2_k127_5211531_13 1123226.KB899283_gene3269 8.143e-21 96.0 COG4538@1|root,COG4538@2|Bacteria,1VZE9@1239|Firmicutes,4I0FW@91061|Bacilli,270ZM@186822|Paenibacillaceae 91061|Bacilli S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 DYD2_k127_5211531_10 1341155.FSS13T_20600 5.429e-47 174.0 COG3295@1|root,COG3295@2|Bacteria,4NNGT@976|Bacteroidetes,1I36S@117743|Flavobacteriia,2NT6S@237|Flavobacterium 976|Bacteroidetes S Putative PepSY_TM-like - - - ko:K09939 - - - - ko00000 - - - PepSY_TM_like_2 DYD2_k127_5211531_0 1122179.KB890419_gene24 0.0 1256.0 COG4447@1|root,COG4447@2|Bacteria,4NI14@976|Bacteroidetes 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_5211531_3 1250232.JQNJ01000001_gene1119 1.607e-151 490.0 COG0624@1|root,COG0624@2|Bacteria,4NJEK@976|Bacteroidetes,1I126@117743|Flavobacteriia 976|Bacteroidetes E Peptidase family M28 - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD2_k127_5211531_1 938709.AUSH02000017_gene948 1.122e-284 886.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes 976|Bacteroidetes EU Peptidase, S9A B C family, catalytic domain protein pop GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - PD40,Peptidase_S9 DYD2_k127_5211531_14 1089548.KI783301_gene939 2.719e-14 87.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 DYD2_k127_5211531_11 1121875.KB907549_gene1707 4.353e-46 190.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 DYD2_k127_5211531_12 1232410.KI421426_gene1317 3.213e-29 120.0 COG3070@1|root,COG3070@2|Bacteria,1QEQQ@1224|Proteobacteria,4318J@68525|delta/epsilon subdivisions,2WWGX@28221|Deltaproteobacteria 28221|Deltaproteobacteria K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N DYD2_k127_5211531_5 1121875.KB907547_gene3050 6.342e-80 284.0 COG0596@1|root,COG0596@2|Bacteria,4NQYB@976|Bacteroidetes,1I318@117743|Flavobacteriia 976|Bacteroidetes S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 DYD2_k127_5214496_0 643867.Ftrac_2465 0.0 1155.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,47JWU@768503|Cytophagia 976|Bacteroidetes J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 DYD2_k127_5214496_1 1237149.C900_03147 1.835e-318 993.0 COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia 976|Bacteroidetes S COGs COG1033 exporter of the RND superfamily protein - - - ko:K07003 - - - - ko00000 - - - MMPL DYD2_k127_5214496_3 1237149.C900_03148 4.718e-175 559.0 COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,47KD3@768503|Cytophagia 976|Bacteroidetes F Deoxyguanosinetriphosphate triphosphohydrolase-like protein dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc DYD2_k127_5214496_5 1124780.ANNU01000006_gene2896 1.016e-38 154.0 COG3228@1|root,COG3228@2|Bacteria,4NMII@976|Bacteroidetes,47QA7@768503|Cytophagia 976|Bacteroidetes S Glucose-regulated metallo-peptidase M90 - - - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 DYD2_k127_5214496_2 1237149.C900_00375 1.033e-274 851.0 COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,47MCS@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-II aminoacyl-tRNA synthetase family glyQS - 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b DYD2_k127_5214496_4 1279009.ADICEAN_02889 1.223e-61 221.0 COG4251@1|root,COG4251@2|Bacteria,4NN9A@976|Bacteroidetes 976|Bacteroidetes T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 DYD2_k127_5215168_0 1121957.ATVL01000006_gene2849 4.621e-220 686.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia 976|Bacteroidetes J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD2_k127_5215168_8 1158294.JOMI01000009_gene919 7.389e-06 48.0 2DR8D@1|root,33ANQ@2|Bacteria,4NYGG@976|Bacteroidetes,2FVPJ@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5215168_6 1279009.ADICEAN_01897 2.493e-25 108.0 COG5512@1|root,COG5512@2|Bacteria,4NXIK@976|Bacteroidetes,47S8C@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 DYD2_k127_5215168_3 1123057.P872_00625 7.129e-108 360.0 COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,47JMB@768503|Cytophagia 976|Bacteroidetes L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - AAA_15,SMC_N DYD2_k127_5215168_1 1237149.C900_04665 1.536e-177 560.0 COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,47M0Z@768503|Cytophagia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD2_k127_5215168_4 1237149.C900_04663 1.661e-79 271.0 COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,47PPQ@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_21,TPR_6,TPR_7,TPR_8 DYD2_k127_5215168_5 1120968.AUBX01000015_gene3601 3.85e-54 194.0 COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,47PCJ@768503|Cytophagia 976|Bacteroidetes H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase DYD2_k127_5215168_2 1121904.ARBP01000001_gene5480 4.482e-139 448.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia 976|Bacteroidetes EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 DYD2_k127_5219960_13 1089550.ATTH01000001_gene669 5.208e-86 297.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes EU Prolyl oligopeptidase family - - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 DYD2_k127_5219960_19 1237149.C900_00491 5.386e-37 145.0 COG2318@1|root,COG2318@2|Bacteria,4NW0H@976|Bacteroidetes 976|Bacteroidetes S DinB family - - - - - - - - - - - - DinB DYD2_k127_5219960_7 1121104.AQXH01000004_gene36 3.934e-124 404.0 COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,1ISZR@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the glutaminase family glsA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase DYD2_k127_5219960_18 1123276.KB893313_gene3800 2.964e-39 160.0 COG0671@1|root,COG0671@2|Bacteria,4NMQW@976|Bacteroidetes,47PHH@768503|Cytophagia 976|Bacteroidetes I Acid phosphatase homologues - - - - - - - - - - - - PAP2 DYD2_k127_5219960_5 1237149.C900_03457 1.432e-161 519.0 COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,47NB9@768503|Cytophagia 976|Bacteroidetes E Peptidase dimerisation domain - - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD2_k127_5219960_0 1237149.C900_01133 4.281e-309 955.0 COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47M5V@768503|Cytophagia 976|Bacteroidetes S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn DYD2_k127_5219960_17 1279009.ADICEAN_03134 3.734e-43 157.0 2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2795) - - - - - - - - - - - - DUF2795 DYD2_k127_5219960_14 1237149.C900_01135 5.438e-86 289.0 COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,47P6K@768503|Cytophagia 976|Bacteroidetes I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD DYD2_k127_5219960_4 643867.Ftrac_2977 7.546e-179 564.0 COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,47J9B@768503|Cytophagia 976|Bacteroidetes J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth DYD2_k127_5219960_2 1237149.C900_01138 3.504e-186 590.0 COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,47J9P@768503|Cytophagia 976|Bacteroidetes V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_5219960_3 1124780.ANNU01000043_gene346 4.427e-186 585.0 COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,47K6D@768503|Cytophagia 976|Bacteroidetes L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD2_k127_5219960_11 1237149.C900_01141 3.545e-105 351.0 COG4324@1|root,COG4324@2|Bacteria,4NF0V@976|Bacteroidetes,47NVX@768503|Cytophagia 976|Bacteroidetes I Putative aminopeptidase - - - - - - - - - - - - Aminopep DYD2_k127_5219960_9 1237149.C900_01143 2.104e-112 366.0 COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,47MJ5@768503|Cytophagia 976|Bacteroidetes T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD2_k127_5219960_10 1237149.C900_01144 1.471e-109 364.0 COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,47JX1@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD2_k127_5219960_12 1239962.C943_04026 1.1e-90 304.0 COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,47KJC@768503|Cytophagia 976|Bacteroidetes J TIGRFAM pseudouridine synthase, RluA family - - 5.4.99.23,5.4.99.24 ko:K06179,ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 DYD2_k127_5219960_15 1048983.EL17_06480 5.567e-58 206.0 COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,47PQ7@768503|Cytophagia 976|Bacteroidetes J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 DYD2_k127_5219960_16 1288963.ADIS_3275 6.447e-47 171.0 COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,47Q9B@768503|Cytophagia 976|Bacteroidetes J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 DYD2_k127_5219960_8 1237149.C900_00092 5.998e-119 388.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,47M3D@768503|Cytophagia 976|Bacteroidetes J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 DYD2_k127_5219960_6 1237149.C900_00090 1.262e-132 427.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,47M4X@768503|Cytophagia 976|Bacteroidetes J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD2_k127_5219960_1 1250232.JQNJ01000001_gene1503 2.338e-242 755.0 COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,1HZF1@117743|Flavobacteriia 976|Bacteroidetes G Alpha-amylase domain malL - 3.2.1.1,3.2.1.10,5.4.99.16 ko:K01182,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01557,R01718,R01791,R02108,R02112,R06199,R11262 RC00028,RC00059,RC00077,RC00451,RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C DYD2_k127_5286045_6 1129374.AJE_17235 2.16e-11 69.0 2DQHA@1|root,336UF@2|Bacteria,1R1KD@1224|Proteobacteria,1SI8U@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_5286045_7 1178825.ALIH01000004_gene2905 1.061e-09 64.0 2DQ1A@1|root,32UNA@2|Bacteria,4NT2M@976|Bacteroidetes,1I4EA@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF1761 DYD2_k127_5286045_4 143224.JQMD01000002_gene688 7.062e-85 286.0 COG2755@1|root,COG2755@2|Bacteria,4NHBT@976|Bacteroidetes,1HYY1@117743|Flavobacteriia 976|Bacteroidetes E COG2755 Lysophospholipase L1 and related - - - - - - - - - - - - Lipase_GDSL_2 DYD2_k127_5286045_0 1121875.KB907552_gene313 0.0 1161.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1HY05@117743|Flavobacteriia 976|Bacteroidetes G Alpha-glucosidase - - 3.2.1.20,3.2.1.3 ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01790,R01791,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31,GH97 - GH97_C,GH97_N,Glyco_hydro_97 DYD2_k127_5286045_5 1476583.DEIPH_ctg044orf0043 1.48e-13 73.0 COG3478@1|root,COG3478@2|Bacteria 2|Bacteria S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) ypzJ - - ko:K07069 - - - - ko00000 - - - zinc_ribbon_13 DYD2_k127_5286045_8 1121373.KB903630_gene297 2.48e-07 53.0 COG0583@1|root,COG0583@2|Bacteria,4NGHS@976|Bacteroidetes,47M6G@768503|Cytophagia 976|Bacteroidetes K LysR family - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_5286045_1 866536.Belba_3185 2.2e-322 1003.0 COG1960@1|root,COG1960@2|Bacteria,4NF87@976|Bacteroidetes,47NXN@768503|Cytophagia 976|Bacteroidetes I Acyl-CoA dehydrogenase, middle domain - - 1.3.3.6 ko:K00232 ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146 M00087,M00113 R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD2_k127_5286045_2 1443665.JACA01000049_gene5425 4.529e-219 695.0 COG0517@1|root,COG0517@2|Bacteria,4NGW0@976|Bacteroidetes,1HYC5@117743|Flavobacteriia 976|Bacteroidetes H Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS,GCS2 DYD2_k127_5286045_3 1443665.JACA01000049_gene5424 1.258e-115 386.0 COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,1HZQK@117743|Flavobacteriia 976|Bacteroidetes E Succinylglutamate desuccinylase / Aspartoacylase family astE - 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - - AstE_AspA DYD2_k127_5305972_9 1237149.C900_02110 1.534e-50 182.0 COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia 976|Bacteroidetes H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB DYD2_k127_5305972_4 1124780.ANNU01000006_gene2828 1.986e-105 351.0 COG2222@1|root,COG2222@2|Bacteria,4NIX0@976|Bacteroidetes,47JG5@768503|Cytophagia 976|Bacteroidetes M Bacterial phospho-glucose isomerase C-terminal SIS domain - - 5.3.1.8,5.3.1.9 ko:K15916 ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R01819,R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 - - - SIS,bact-PGI_C DYD2_k127_5305972_11 761193.Runsl_1319 6.675e-36 139.0 COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,47QW9@768503|Cytophagia 976|Bacteroidetes L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 DYD2_k127_5305972_5 1237149.C900_01531 8.04e-94 315.0 COG2849@1|root,COG2849@2|Bacteria,4NK1X@976|Bacteroidetes,47NFY@768503|Cytophagia 976|Bacteroidetes S repeat protein - - - - - - - - - - - - - DYD2_k127_5305972_0 1237149.C900_03488 2e-323 998.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,47JAZ@768503|Cytophagia 976|Bacteroidetes O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c_3,HSP90 DYD2_k127_5305972_1 1237149.C900_04526 3.916e-246 769.0 COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,47KC6@768503|Cytophagia 976|Bacteroidetes J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD2_k127_5305972_13 714943.Mucpa_2551 4.127e-06 48.0 2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5305972_7 1123057.P872_01010 5.784e-66 234.0 COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,47KT9@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 DYD2_k127_5305972_10 1121373.KB903620_gene2207 9.485e-44 161.0 COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,47QBN@768503|Cytophagia 976|Bacteroidetes L Belongs to the bacterial histone-like protein family hupA - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD2_k127_5305972_3 929562.Emtol_2241 1.616e-117 388.0 COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,47KTH@768503|Cytophagia 976|Bacteroidetes L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 DYD2_k127_5305972_8 1237149.C900_04530 5.227e-64 222.0 COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia 976|Bacteroidetes L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB DYD2_k127_5305972_2 1237149.C900_04531 5.868e-162 521.0 COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,47JUX@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated protein GldE gldE - - - - - - - - - - - CBS,CorC_HlyC,DUF21 DYD2_k127_5305972_6 1237149.C900_04532 2.073e-74 254.0 293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,47PUM@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated lipoprotein GldD gldD - - - - - - - - - - - - DYD2_k127_5305972_12 1124780.ANNU01000015_gene2023 4.838e-33 129.0 COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,47JUE@768503|Cytophagia 976|Bacteroidetes L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge DYD2_k127_5309260_3 1121904.ARBP01000002_gene6807 1.772e-131 430.0 COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,47KQB@768503|Cytophagia 976|Bacteroidetes G PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme - - 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase DYD2_k127_5309260_2 1121904.ARBP01000012_gene1193 1.488e-184 604.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_5309260_7 1353276.JADR01000005_gene2437 1.249e-48 191.0 28JVJ@1|root,2Z9KI@2|Bacteria,4NDVQ@976|Bacteroidetes,1HYUZ@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5309260_5 509635.N824_00840 1.413e-114 376.0 COG0491@1|root,COG0491@2|Bacteria,4NH8C@976|Bacteroidetes,1IVMC@117747|Sphingobacteriia 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B DYD2_k127_5309260_4 700598.Niako_7343 2.608e-115 379.0 COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1INST@117747|Sphingobacteriia 976|Bacteroidetes K transcriptional regulator oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate DYD2_k127_5309260_0 504472.Slin_5085 0.0 1269.0 COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia 976|Bacteroidetes P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase DYD2_k127_5309260_6 866536.Belba_3189 2.026e-79 292.0 COG0457@1|root,COG5002@1|root,COG0457@2|Bacteria,COG5002@2|Bacteria,4NI29@976|Bacteroidetes,47KZN@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,TPR_10,TPR_12,TPR_7,TPR_8 DYD2_k127_5309260_1 1121875.KB907549_gene1727 0.0 1151.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD2_k127_5328294_22 1120951.AUBG01000005_gene2194 1.172e-37 148.0 COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,1HZ1F@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - TetR_N DYD2_k127_5328294_15 760192.Halhy_3541 7.894e-129 424.0 COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,1IR65@117747|Sphingobacteriia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP DYD2_k127_5328294_19 525257.HMPREF0204_13086 3.352e-95 322.0 COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes,1IK49@117743|Flavobacteriia 976|Bacteroidetes V Biotin-lipoyl like - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD2_k127_5328294_16 694427.Palpr_2716 2.819e-128 417.0 COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,2FWZE@200643|Bacteroidia,22W0S@171551|Porphyromonadaceae 976|Bacteroidetes V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_5328294_17 700598.Niako_4470 8.165e-118 382.0 COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1IWS4@117747|Sphingobacteriia 976|Bacteroidetes V COGs COG1131 ABC-type multidrug transport system ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD2_k127_5328294_10 700598.Niako_4469 1.266e-156 501.0 COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes 976|Bacteroidetes V transport, permease protein ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD2_k127_5328294_9 700598.Niako_4468 2.533e-163 521.0 COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes 976|Bacteroidetes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD2_k127_5328294_20 1237149.C900_04644 1.573e-53 200.0 2BYCP@1|root,2ZAHR@2|Bacteria,4NJ23@976|Bacteroidetes,47NMK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5328294_23 926549.KI421517_gene1919 5.351e-27 113.0 COG2146@1|root,COG2146@2|Bacteria,4NVFP@976|Bacteroidetes,47S4K@768503|Cytophagia 976|Bacteroidetes P Rieske [2Fe-2S] domain - - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske DYD2_k127_5328294_8 1237149.C900_04632 1.498e-173 554.0 COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase family M20 M25 M40 - - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 DYD2_k127_5328294_7 1250006.JHZZ01000001_gene2023 5.059e-177 567.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1HZT3@117743|Flavobacteriia,3VX1R@52959|Polaribacter 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 DYD2_k127_5328294_2 1239962.C943_00789 5.844e-289 901.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia 976|Bacteroidetes EU Peptidase S9 prolyl oligopeptidase active site domain protein - - - - - - - - - - - - FGE-sulfatase,PD40,Peptidase_S9 DYD2_k127_5328294_4 1189612.A33Q_2921 8.537e-219 700.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MZC@768503|Cytophagia 976|Bacteroidetes EU Peptidase S9, prolyl oligopeptidase active site domain protein - - - - - - - - - - - - PD40,Peptidase_S9 DYD2_k127_5328294_13 1123277.KB893172_gene907 6.879e-137 446.0 COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia 976|Bacteroidetes J SAM-dependent methyltransferase rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM DYD2_k127_5328294_18 313596.RB2501_12999 6.783e-96 338.0 COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NJD5@976|Bacteroidetes,1IINW@117743|Flavobacteriia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c DYD2_k127_5328294_21 1237149.C900_01549 1.607e-51 188.0 COG2849@1|root,COG2849@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - MORN_2 DYD2_k127_5328294_11 1237149.C900_01547 7.056e-156 506.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia 976|Bacteroidetes O PDZ domain (Also known as DHR or GLGF) - - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 DYD2_k127_5328294_5 1121904.ARBP01000002_gene7252 1.578e-215 696.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_5328294_0 1237149.C900_00841 3.997e-295 925.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_5328294_3 1237149.C900_00838 1.549e-233 748.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47U5S@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_5328294_1 1237149.C900_01529 7.903e-290 910.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_5328294_12 1121481.AUAS01000017_gene2476 2.212e-144 472.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD2_k127_5328294_14 1237149.C900_01526 9.154e-135 442.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c DYD2_k127_5328294_6 1237149.C900_00764 2.57e-194 612.0 COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M0Y@768503|Cytophagia 976|Bacteroidetes C Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB DYD2_k127_5358294_1 1124780.ANNU01000024_gene3046 3.223e-86 287.0 COG1012@1|root,COG1012@2|Bacteria 2|Bacteria C belongs to the aldehyde dehydrogenase family paaN - - - - - - - - - - - Aldedh DYD2_k127_5358294_4 1034807.FBFL15_0028 1.336e-28 121.0 2A2MK@1|root,30QZX@2|Bacteria,4P5NJ@976|Bacteroidetes,1IDRG@117743|Flavobacteriia,2NZ12@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5358294_0 1120968.AUBX01000018_gene2117 1.96e-106 361.0 COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,47NWS@768503|Cytophagia 976|Bacteroidetes V Inner membrane protein CreD creD - - ko:K06143 - - - - ko00000 - - - CreD DYD2_k127_5358294_3 714943.Mucpa_1260 3.513e-35 138.0 COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,1IT7Z@117747|Sphingobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - HTH_34 DYD2_k127_5358294_2 1150600.ADIARSV_3179 1.319e-39 150.0 COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1IRV7@117747|Sphingobacteriia 976|Bacteroidetes Q membrane - - - - - - - - - - - - - DYD2_k127_5378967_10 742725.HMPREF9450_01984 2.241e-07 59.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,2FU05@200643|Bacteroidia,22UK4@171550|Rikenellaceae 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 DYD2_k127_5378967_11 1538644.KO02_07905 1.13e-05 55.0 COG3047@1|root,COG3047@2|Bacteria,4NNDW@976|Bacteroidetes 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - ko:K07275 - - - - ko00000 - - - OMP_b-brl DYD2_k127_5378967_6 313606.M23134_07170 6.438e-60 231.0 COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,4NN66@976|Bacteroidetes,47Q5A@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14 DYD2_k127_5378967_0 1124780.ANNU01000010_gene3624 0.0 1048.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia 976|Bacteroidetes O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD2_k127_5378967_8 1168289.AJKI01000026_gene1417 1.618e-32 138.0 2DKFZ@1|root,309D6@2|Bacteria,4PP8C@976|Bacteroidetes,2FZR5@200643|Bacteroidia,3XJRP@558415|Marinilabiliaceae 976|Bacteroidetes S Domain of unknown function (DUF4382) - - - - - - - - - - - - DUF4382 DYD2_k127_5378967_2 1237149.C900_03255 3.321e-161 518.0 COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,47KM0@768503|Cytophagia 976|Bacteroidetes E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD2_k127_5378967_7 391603.FBALC1_13917 7.075e-48 176.0 COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia 976|Bacteroidetes P Na H antiporter NhaD and related arsenite nhaD - - - - - - - - - - - CitMHS DYD2_k127_5378967_4 313603.FB2170_17431 5.243e-152 486.0 COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,1HYB2@117743|Flavobacteriia,2PGGP@252356|Maribacter 976|Bacteroidetes P Citrate transporter nhaD - - - - - - - - - - - CitMHS DYD2_k127_5378967_3 929562.Emtol_3103 2.482e-159 513.0 COG1055@1|root,COG1055@2|Bacteria,4NGP4@976|Bacteroidetes,47JIU@768503|Cytophagia 976|Bacteroidetes P Na H antiporter NhaD and related arsenite nhaD - - - - - - - - - - - CitMHS DYD2_k127_5378967_5 1237149.C900_05645 6.758e-97 326.0 COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47UAQ@768503|Cytophagia 976|Bacteroidetes P Sodium/calcium exchanger protein yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD2_k127_5378967_1 1237149.C900_04908 4.059e-200 630.0 COG0334@1|root,COG0334@2|Bacteria,4NG6Y@976|Bacteroidetes,47KWD@768503|Cytophagia 976|Bacteroidetes E Glu Leu Phe Val dehydrogenase - - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD2_k127_5378967_9 938709.AUSH02000045_gene555 4.573e-27 115.0 COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes 976|Bacteroidetes O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK DYD2_k127_5390834_3 1137281.D778_01099 1.7e-223 703.0 COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1HZ97@117743|Flavobacteriia 976|Bacteroidetes E Phosphotransferase enzyme family - - - - - - - - - - - - APH,Aminotran_3,Peptidase_M23 DYD2_k127_5390834_5 1279009.ADICEAN_03440 5.929e-167 531.0 COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,47MHY@768503|Cytophagia 976|Bacteroidetes G beta-1,4-mannooligosaccharide phosphorylase - - 3.2.1.197 ko:K21065 - - R11544 RC00049 ko00000,ko01000 - - - Glyco_hydro_130 DYD2_k127_5390834_19 1237149.C900_00134 7.036e-58 211.0 COG0589@1|root,COG0589@2|Bacteria,4NR8D@976|Bacteroidetes,47QEW@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp DYD2_k127_5390834_2 760192.Halhy_5327 5.284e-236 739.0 COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1ISNT@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase S10 - - - - - - - - - - - - Peptidase_S10 DYD2_k127_5390834_18 1519464.HY22_09275 6.06e-60 215.0 COG1028@1|root,COG1028@2|Bacteria 1519464.HY22_09275|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - DYD2_k127_5390834_10 313606.M23134_05392 2.884e-116 381.0 COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,47NQU@768503|Cytophagia 976|Bacteroidetes S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase DYD2_k127_5390834_4 1121887.AUDK01000028_gene1511 1.965e-173 561.0 COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia,2NSE8@237|Flavobacterium 976|Bacteroidetes P Transporter - - - ko:K03281 - - - - ko00000 2.A.49 - - CBS,Voltage_CLC DYD2_k127_5390834_26 153721.MYP_3893 5.066e-16 90.0 COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,47PQF@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8 DYD2_k127_5390834_0 1237149.C900_04189 0.0 1303.0 COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,47K30@768503|Cytophagia 976|Bacteroidetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD2_k127_5390834_13 1237149.C900_01235 2.887e-83 287.0 2EG6T@1|root,339YP@2|Bacteria,4NXNK@976|Bacteroidetes,47T48@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5390834_7 1237149.C900_01232 4.87e-159 514.0 COG3014@1|root,COG3014@2|Bacteria,4NIIU@976|Bacteroidetes,47K7B@768503|Cytophagia 976|Bacteroidetes S protein conserved in bacteria - - - ko:K09859 - - - - ko00000 - - - TPR_2 DYD2_k127_5390834_15 1237149.C900_01231 4.609e-72 247.0 COG3417@1|root,COG3417@2|Bacteria,4NFXF@976|Bacteroidetes,47Q1R@768503|Cytophagia 976|Bacteroidetes M Peptidoglycan-synthase activator LpoB - - - ko:K07337 - - - - ko00000 - - - LpoB DYD2_k127_5390834_12 1237149.C900_01229 5.381e-104 341.0 COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,47N3P@768503|Cytophagia 976|Bacteroidetes G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim DYD2_k127_5390834_11 1279009.ADICEAN_01972 1.109e-109 374.0 COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,47KS3@768503|Cytophagia 976|Bacteroidetes O Peptidase S8 and S53 subtilisin kexin sedolisin aprN - - - - - - - - - - - Peptidase_S8 DYD2_k127_5390834_24 1313421.JHBV01000040_gene2591 1.264e-19 98.0 298K1@1|root,3122S@2|Bacteria,4PGXN@976|Bacteroidetes,1IUN3@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5390834_23 1237149.C900_01223 4.308e-22 104.0 COG0135@1|root,COG0135@2|Bacteria,4NMKY@976|Bacteroidetes,47RUF@768503|Cytophagia 976|Bacteroidetes E PFAM N-(5'phosphoribosyl)anthranilate (PRA) isomerase - - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI DYD2_k127_5390834_14 1237149.C900_03416 1.407e-79 271.0 COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,47JY6@768503|Cytophagia 976|Bacteroidetes J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 DYD2_k127_5390834_8 714943.Mucpa_1462 3.647e-150 486.0 COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia 976|Bacteroidetes H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M DYD2_k127_5390834_17 1237149.C900_00012 1.325e-69 241.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,47QK5@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 DYD2_k127_5390834_27 1392490.JHZX01000001_gene3078 9.226e-08 61.0 COG3637@1|root,COG3637@2|Bacteria,4NPFD@976|Bacteroidetes,1I2KB@117743|Flavobacteriia 976|Bacteroidetes M Autotransporter beta-domain - - - - - - - - - - - - OMP_b-brl DYD2_k127_5390834_21 1267211.KI669560_gene569 2.122e-55 199.0 COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1IYKW@117747|Sphingobacteriia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase DYD2_k127_5390834_1 1008457.BAEX01000101_gene2217 0.0 1082.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,1HXQQ@117743|Flavobacteriia,47HCT@76831|Myroides 976|Bacteroidetes E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N DYD2_k127_5390834_16 1121859.KB890759_gene1939 5.476e-70 245.0 COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,47JZ5@768503|Cytophagia 976|Bacteroidetes S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin DYD2_k127_5390834_9 1237149.C900_00003 9.564e-144 459.0 COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,47JCR@768503|Cytophagia 976|Bacteroidetes S PFAM Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD2_k127_5390834_25 1279009.ADICEAN_02396 1.144e-16 86.0 2928S@1|root,2ZPTC@2|Bacteria,4P8WI@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5390834_6 1237149.C900_00002 2.75e-161 512.0 COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,47JPY@768503|Cytophagia 976|Bacteroidetes I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA DYD2_k127_5390834_20 1250232.JQNJ01000001_gene714 8.484e-57 211.0 COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,1HYY0@117743|Flavobacteriia 976|Bacteroidetes T Adenylate and Guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc DYD2_k127_5390834_22 1237149.C900_04902 2.316e-40 161.0 COG0729@1|root,COG0729@2|Bacteria,4NMUN@976|Bacteroidetes,47Y0X@768503|Cytophagia 976|Bacteroidetes M outer membrane protein protective antigen - - - - - - - - - - - - Bac_surface_Ag DYD2_k127_5449667_0 1121904.ARBP01000008_gene3401 6.822e-208 662.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_5449667_1 1121904.ARBP01000008_gene3400 6.033e-46 168.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 2|Bacteria K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR DYD2_k127_5471321_6 1237149.C900_05665 8.225e-63 218.0 COG1522@1|root,COG1522@2|Bacteria,4NHG9@976|Bacteroidetes,47PXD@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix ASNC type asnC - - ko:K03718 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type DYD2_k127_5471321_0 1237149.C900_05664 1.926e-286 882.0 COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,47JZJ@768503|Cytophagia 976|Bacteroidetes O TIGRFAM FeS assembly protein SufB sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 DYD2_k127_5471321_3 269798.CHU_0977 1.237e-132 425.0 COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,47N88@768503|Cytophagia 976|Bacteroidetes O TIGRFAM FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran DYD2_k127_5471321_4 1237149.C900_05661 1.733e-114 383.0 COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,47K0R@768503|Cytophagia 976|Bacteroidetes O TIGRFAM FeS assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 DYD2_k127_5471321_1 1237149.C900_05660 3.556e-196 619.0 COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,47JNS@768503|Cytophagia 976|Bacteroidetes E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 DYD2_k127_5471321_7 1237149.C900_05659 1.68e-60 212.0 COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,47Q7A@768503|Cytophagia 976|Bacteroidetes S SufE protein probably involved in Fe-S center assembly sufE - - ko:K02426 - - - - ko00000 - - - SufE DYD2_k127_5471321_9 643867.Ftrac_0912 1.651e-49 178.0 COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,47QBC@768503|Cytophagia 976|Bacteroidetes S FeS assembly SUF system protein yitW - - - - - - - - - - - FeS_assembly_P DYD2_k127_5471321_5 643867.Ftrac_0913 6.202e-68 232.0 28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,47QD1@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0403 family yqiW - - - - - - - - - - - Disulph_isomer DYD2_k127_5471321_2 376686.Fjoh_4062 2.801e-148 486.0 COG0025@1|root,COG0025@2|Bacteria,4NK9T@976|Bacteroidetes,1II55@117743|Flavobacteriia,2NUEX@237|Flavobacterium 976|Bacteroidetes P Sodium proton - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger DYD2_k127_5471321_12 643867.Ftrac_2983 0.0001124 46.0 COG1361@1|root,COG2931@1|root,COG3391@1|root,COG3420@1|root,COG3468@1|root,COG5492@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG3420@2|Bacteria,COG3468@2|Bacteria,COG5492@2|Bacteria,4PMF3@976|Bacteroidetes,47Y61@768503|Cytophagia 976|Bacteroidetes MN Parallel beta-helix repeats - - - - - - - - - - - - CHU_C,VCBS DYD2_k127_5471321_11 1189619.pgond44_14598 5.988e-19 99.0 2E0EQ@1|root,32W15@2|Bacteria,4NTKT@976|Bacteroidetes,1I3XF@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5471321_8 1469557.JSWF01000012_gene1201 1.426e-57 229.0 COG3342@1|root,COG3342@2|Bacteria 2|Bacteria S Family of unknown function (DUF1028) - - 4.6.1.13 ko:K01771 ko00562,map00562 - R03332 RC00017,RC00425 ko00000,ko00001,ko01000 - - - Crystall,DUF1028,MAM,fn3 DYD2_k127_5471321_10 153721.MYP_3535 7.882e-35 155.0 COG2152@1|root,COG3291@1|root,COG4932@1|root,COG2152@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4PHTS@976|Bacteroidetes,47Q40@768503|Cytophagia 976|Bacteroidetes DZ regulator of chromosome condensation, RCC1 - - - - - - - - - - - - CHU_C DYD2_k127_5495424_3 926556.Echvi_2307 1.266e-181 590.0 COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,47KA3@768503|Cytophagia 976|Bacteroidetes L Helix-hairpin-helix motif - - - - - - - - - - - - HHH_3 DYD2_k127_5495424_9 1237149.C900_01629 4.976e-52 195.0 COG1555@1|root,COG1555@2|Bacteria,4NQC1@976|Bacteroidetes,47Q92@768503|Cytophagia 976|Bacteroidetes L photosystem II stabilization - - - - - - - - - - - - - DYD2_k127_5495424_10 1121904.ARBP01000002_gene6994 3.569e-50 185.0 COG2849@1|root,COG2849@2|Bacteria,4NSYD@976|Bacteroidetes,47RIN@768503|Cytophagia 976|Bacteroidetes S MORN repeat variant - - - - - - - - - - - - MORN_2 DYD2_k127_5495424_4 1237149.C900_01627 6.929e-144 471.0 COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia 976|Bacteroidetes M PFAM surface antigen variable number repeat - - - - - - - - - - - - Bac_surface_Ag,POTRA DYD2_k127_5495424_7 1124780.ANNU01000045_gene2308 1.047e-97 331.0 COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,47KQC@768503|Cytophagia 976|Bacteroidetes M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - - - - - - - - - - LGT DYD2_k127_5495424_0 1124780.ANNU01000045_gene2309 3.762e-223 707.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NHXQ@976|Bacteroidetes,47JFU@768503|Cytophagia 976|Bacteroidetes H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase DYD2_k127_5495424_8 1237149.C900_01621 1.054e-84 287.0 COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,47K17@768503|Cytophagia 976|Bacteroidetes J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm DYD2_k127_5495424_1 1120966.AUBU01000003_gene1625 4.118e-216 676.0 COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,47MQI@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD2_k127_5495424_11 1237149.C900_01619 5.489e-39 145.0 COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,47R56@768503|Cytophagia 976|Bacteroidetes IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD2_k127_5495424_2 1237149.C900_01617 1.923e-197 626.0 COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,47JS3@768503|Cytophagia 976|Bacteroidetes G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C DYD2_k127_5495424_5 1237149.C900_01616 2.872e-131 435.0 COG1293@1|root,COG1293@2|Bacteria,4NGP5@976|Bacteroidetes,47M54@768503|Cytophagia 976|Bacteroidetes K Fibronectin-binding protein A N-terminus (FbpA) - - - - - - - - - - - - DUF814,FbpA DYD2_k127_5495424_6 1120965.AUBV01000001_gene3250 2.144e-107 353.0 COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,47JF0@768503|Cytophagia 976|Bacteroidetes S of the beta-lactamase superfamily I phnP - 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 DYD2_k127_5495424_12 643867.Ftrac_0832 1.591e-32 128.0 2E4YQ@1|root,32ZSH@2|Bacteria,4NVKX@976|Bacteroidetes,47RX3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5495475_7 1122176.KB903543_gene527 1.289e-06 51.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_5495475_8 391603.FBALC1_08738 1.321e-05 49.0 COG2267@1|root,COG2267@2|Bacteria,4NKKQ@976|Bacteroidetes,1I718@117743|Flavobacteriia 976|Bacteroidetes I Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 DYD2_k127_5495475_1 1123248.KB893327_gene788 3.074e-120 392.0 COG0258@1|root,COG0258@2|Bacteria 2|Bacteria L nuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 DYD2_k127_5495475_2 616991.JPOO01000003_gene668 2.905e-50 181.0 COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1I2YF@117743|Flavobacteriia,23HIK@178469|Arenibacter 976|Bacteroidetes O OsmC-like protein osmC - - ko:K04063 - - - - ko00000 - - - OsmC DYD2_k127_5495475_0 388413.ALPR1_12130 9.313e-310 960.0 COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia 976|Bacteroidetes O PFAM peptidase M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N DYD2_k127_5495475_4 1501230.ET33_03090 8.333e-36 139.0 COG2259@1|root,31BQE@2|Bacteria,1VXQN@1239|Firmicutes,4HXCN@91061|Bacilli,26YSK@186822|Paenibacillaceae 91061|Bacilli S DoxX-like family - - - - - - - - - - - - DoxX_2 DYD2_k127_5495475_6 1122176.KB903544_gene789 4.412e-25 113.0 2D0I5@1|root,32T8N@2|Bacteria,4NSMU@976|Bacteroidetes,1J0DQ@117747|Sphingobacteriia 976|Bacteroidetes S Four helix bundle sensory module for signal transduction - - - - - - - - - - - - 4HB_MCP_1 DYD2_k127_5495475_5 1121904.ARBP01000004_gene1023 1.129e-29 122.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 2|Bacteria K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR DYD2_k127_5495475_3 1550091.JROE01000008_gene3584 9.382e-46 179.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_5533240_1 1408433.JHXV01000014_gene3642 2.91e-147 489.0 COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,1I8HX@117743|Flavobacteriia,2PAB4@246874|Cryomorphaceae 976|Bacteroidetes S Lamin Tail Domain - - - - - - - - - - - - Big_5,CHU_C,LTD DYD2_k127_5533240_0 1237149.C900_00911 8.344e-159 505.0 COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,47JMK@768503|Cytophagia 976|Bacteroidetes E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD2_k127_5533240_2 388413.ALPR1_01545 1.891e-27 114.0 COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,47JGT@768503|Cytophagia 976|Bacteroidetes S PFAM LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA DYD2_k127_5534240_2 1237149.C900_05719 1.495e-63 226.0 COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia 976|Bacteroidetes H PFAM Biotin lipoate A B protein ligase birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_LplA_LipB DYD2_k127_5534240_3 1237149.C900_05720 8.779e-46 168.0 COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia 976|Bacteroidetes S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD2_k127_5534240_0 1237149.C900_05721 0.0 1031.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,47KKF@768503|Cytophagia 976|Bacteroidetes O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD2_k127_5534240_1 1237149.C900_05722 3.383e-114 372.0 COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,47JQJ@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 DYD2_k127_5638057_8 1237149.C900_03740 5.558e-51 189.0 28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,47RCK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5638057_2 1237149.C900_03737 1.189e-134 441.0 COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,47MDG@768503|Cytophagia 976|Bacteroidetes M PFAM 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) waaA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N DYD2_k127_5638057_3 1237149.C900_03736 2.455e-101 340.0 COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,47JC5@768503|Cytophagia 976|Bacteroidetes S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N DYD2_k127_5638057_5 1237149.C900_04066 2.492e-86 293.0 COG1216@1|root,COG1216@2|Bacteria,4NJQR@976|Bacteroidetes,47MWK@768503|Cytophagia 976|Bacteroidetes S PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD2_k127_5638057_11 1227739.Hsw_2553 4.397e-30 131.0 COG5653@1|root,COG5653@2|Bacteria,4NKJS@976|Bacteroidetes,47NWT@768503|Cytophagia 976|Bacteroidetes M Protein involved in cellulose biosynthesis - - - - - - - - - - - - Acetyltransf_6,FemAB DYD2_k127_5638057_6 1237149.C900_04058 1.84e-72 250.0 COG2050@1|root,COG2050@2|Bacteria,4P2ZC@976|Bacteroidetes 976|Bacteroidetes Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 DYD2_k127_5638057_1 1124780.ANNU01000056_gene3481 7.798e-192 609.0 COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,47KKY@768503|Cytophagia 976|Bacteroidetes C TIGRFAM Na H antiporter NhaC nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter DYD2_k127_5638057_7 1237149.C900_05499 1.02e-57 206.0 COG0349@1|root,COG0349@2|Bacteria,4NP3B@976|Bacteroidetes,47QFS@768503|Cytophagia 976|Bacteroidetes J 3'-5' exonuclease rnd - - - - - - - - - - - DNA_pol_A_exo1 DYD2_k127_5638057_9 1123057.P872_16510 1.647e-43 168.0 2DBXN@1|root,2ZBQR@2|Bacteria,4NN54@976|Bacteroidetes,47PK0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - CarbopepD_reg_2 DYD2_k127_5638057_12 398579.Spea_0921 1.978e-11 67.0 COG0738@1|root,COG0738@2|Bacteria,1QX0S@1224|Proteobacteria,1T32Q@1236|Gammaproteobacteria,2QEUA@267890|Shewanellaceae 1236|Gammaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_5638057_4 234267.Acid_2224 2.516e-100 339.0 COG0624@1|root,COG0624@2|Bacteria,3Y7TX@57723|Acidobacteria 57723|Acidobacteria E Peptidase family M20/M25/M40 - - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD2_k127_5638057_10 373994.Riv7116_4482 3.222e-41 156.0 COG0251@1|root,COG0251@2|Bacteria,1G6TD@1117|Cyanobacteria,1HK8V@1161|Nostocales 1117|Cyanobacteria J TIGRFAM endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP DYD2_k127_5638057_0 1185876.BN8_04332 5.287e-285 893.0 COG2866@1|root,COG2866@2|Bacteria,4NF3D@976|Bacteroidetes,47UEQ@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 DYD2_k127_565379_4 1237149.C900_05060 1.505e-108 355.0 COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,47MP4@768503|Cytophagia 976|Bacteroidetes D PFAM ABC transporter ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran DYD2_k127_565379_3 880070.Cycma_0309 2.369e-117 380.0 COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,47JX6@768503|Cytophagia 976|Bacteroidetes G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA DYD2_k127_565379_8 1304275.C41B8_09306 1.119e-28 122.0 COG1670@1|root,COG1670@2|Bacteria,1RKKE@1224|Proteobacteria,1S47R@1236|Gammaproteobacteria 1236|Gammaproteobacteria J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 DYD2_k127_565379_5 945713.IALB_2920 8.146e-64 235.0 COG2114@1|root,COG2114@2|Bacteria 2|Bacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc DYD2_k127_565379_2 1237149.C900_04487 2.092e-127 419.0 COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,47KP1@768503|Cytophagia 976|Bacteroidetes S PFAM Metal-dependent phosphohydrolase, HD - - - - - - - - - - - - HD DYD2_k127_565379_0 1237149.C900_00480 0.0 1259.0 COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,47JAP@768503|Cytophagia 976|Bacteroidetes M Calcineurin-like phosphoesterase - - - - - - - - - - - - Bac_surface_Ag,Metallophos DYD2_k127_565379_6 761193.Runsl_3694 1.685e-46 173.0 2B1RZ@1|root,31U7Q@2|Bacteria,4NR0B@976|Bacteroidetes,47Q5B@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_565379_7 402777.KB235904_gene3963 6.329e-44 173.0 COG2202@1|root,COG4251@1|root,COG5278@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5278@2|Bacteria,1G0A1@1117|Cyanobacteria,1H7JR@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - CHASE3,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 DYD2_k127_565379_1 1237149.C900_03297 5.309e-241 762.0 COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,47JHJ@768503|Cytophagia 976|Bacteroidetes O PFAM peptidase M13 pepO - 3.4.24.71 ko:K01415,ko:K07386 - - - - ko00000,ko01000,ko01002,ko04147 - - - Peptidase_M13,Peptidase_M13_N DYD2_k127_5701946_4 1237149.C900_01732 6.365e-28 123.0 COG0815@1|root,COG0815@2|Bacteria 2|Bacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase DYD2_k127_5701946_1 1237149.C900_01731 4.166e-99 327.0 COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia 976|Bacteroidetes H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase DYD2_k127_5701946_3 1120965.AUBV01000004_gene903 4.335e-32 126.0 COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,47RW0@768503|Cytophagia 976|Bacteroidetes H PFAM Pterin 4 alpha carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a DYD2_k127_5701946_5 1237149.C900_01728 2.859e-24 104.0 COG2921@1|root,COG2921@2|Bacteria,4P9XR@976|Bacteroidetes,47S9P@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF493) - - - - - - - - - - - - DUF493 DYD2_k127_5701946_0 1237149.C900_01727 7.004e-217 693.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,47KBN@768503|Cytophagia 976|Bacteroidetes O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_2 DYD2_k127_5701946_2 663932.KB902575_gene2386 6.812e-59 211.0 COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,2JTER@204441|Rhodospirillales 204441|Rhodospirillales L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 DYD2_k127_5733599_2 1121875.KB907550_gene626 1.434e-240 754.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia 976|Bacteroidetes Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 DYD2_k127_5733599_11 1288963.ADIS_0319 3.062e-31 124.0 COG2388@1|root,COG2388@2|Bacteria,4NUS6@976|Bacteroidetes,47RZM@768503|Cytophagia 976|Bacteroidetes S GCN5-related N-acetyl-transferase - - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG DYD2_k127_5733599_1 1237149.C900_04994 4.564e-256 797.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,47KJE@768503|Cytophagia 976|Bacteroidetes S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 DYD2_k127_5733599_10 1237149.C900_04992 5.919e-32 126.0 COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,47S0D@768503|Cytophagia 976|Bacteroidetes D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA DYD2_k127_5733599_13 1237149.C900_04991 1.377e-26 111.0 2DSW7@1|root,33HNN@2|Bacteria,4NY8S@976|Bacteroidetes,47SU0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5733599_0 1237149.C900_04990 1.04e-321 1002.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,47JAK@768503|Cytophagia 976|Bacteroidetes J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind DYD2_k127_5733599_9 1237149.C900_04988 1.591e-53 194.0 COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47Q5N@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 DYD2_k127_5733599_6 760192.Halhy_0905 9.563e-99 336.0 COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia 976|Bacteroidetes V COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - 3.5.2.6 ko:K01467 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000 - - - Beta-lactamase DYD2_k127_5733599_7 929562.Emtol_2898 4.741e-93 312.0 COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia 976|Bacteroidetes E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC DYD2_k127_5733599_14 1189612.A33Q_1767 4.659e-25 106.0 COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,47R98@768503|Cytophagia 976|Bacteroidetes J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p DYD2_k127_5733599_3 760192.Halhy_2292 6.365e-175 565.0 COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1IRN9@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Peptidase M1 membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,Peptidase_M1 DYD2_k127_5733599_4 1237149.C900_04984 1.466e-121 398.0 28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,47JAX@768503|Cytophagia 976|Bacteroidetes S S1 P1 nuclease - - - - - - - - - - - - S1-P1_nuclease,Zn_dep_PLPC DYD2_k127_5733599_5 1237149.C900_03673 3.03e-105 353.0 COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,47JZE@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD2_k127_5733599_8 1237149.C900_03672 1.772e-73 250.0 COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,47JCE@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_5750073_2 760192.Halhy_1783 6.998e-57 205.0 2DI69@1|root,30258@2|Bacteria,4PJ1K@976|Bacteroidetes,1IZ7W@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5750073_1 1408473.JHXO01000010_gene3726 3.309e-130 424.0 COG0604@1|root,COG0604@2|Bacteria,4NHHT@976|Bacteroidetes,2FR11@200643|Bacteroidia 976|Bacteroidetes C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_N_2,ADH_zinc_N_2 DYD2_k127_5750073_0 1121904.ARBP01000003_gene6331 0.0 1020.0 COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47N72@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 DYD2_k127_5785420_3 1411123.JQNH01000001_gene2863 0.0009685 48.0 28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF2793) - - - - - - - - - - - - DUF2793 DYD2_k127_5785420_1 1305737.JAFX01000001_gene3254 9.891e-87 291.0 COG0357@1|root,COG0357@2|Bacteria,4NEJG@976|Bacteroidetes,47KEA@768503|Cytophagia 976|Bacteroidetes J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB DYD2_k127_5785420_0 1123277.KB893228_gene2069 1.146e-136 444.0 COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,47NWH@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase pbpE - - - - - - - - - - - Beta-lactamase,DUF3471 DYD2_k127_5785420_2 1237149.C900_03672 1.894e-34 132.0 COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,47JCE@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_5863490_8 504472.Slin_1437 1.289e-12 67.0 COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,4NVG3@976|Bacteroidetes,47QRI@768503|Cytophagia 976|Bacteroidetes S Divergent 4Fe-4S mono-cluster - - - - - - - - - - - - Fer4_19,zf-CDGSH DYD2_k127_5863490_7 762903.Pedsa_3013 2.032e-42 162.0 2DYGZ@1|root,32V5E@2|Bacteria,4NSGC@976|Bacteroidetes,1IYVN@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF3575) - - - - - - - - - - - - DUF3575 DYD2_k127_5863490_1 1047013.AQSP01000095_gene2303 7.688e-130 443.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_5863490_4 761193.Runsl_2124 2.093e-79 272.0 COG0745@1|root,COG0745@2|Bacteria,4NGNK@976|Bacteroidetes,47M5N@768503|Cytophagia 976|Bacteroidetes T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C DYD2_k127_5863490_3 1237149.C900_00252 1.397e-84 297.0 COG0642@1|root,COG2205@2|Bacteria,4NI8C@976|Bacteroidetes,47YET@768503|Cytophagia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD2_k127_5863490_5 1237149.C900_00250 2.69e-63 225.0 28J3Q@1|root,32URP@2|Bacteria,4NT50@976|Bacteroidetes,47R3P@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (Porph_ging) - - - - - - - - - - - - Porph_ging DYD2_k127_5863490_0 1237149.C900_00249 5.075e-270 859.0 COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3 DYD2_k127_5863490_2 1237149.C900_04937 4.283e-110 363.0 COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes,47MFN@768503|Cytophagia 976|Bacteroidetes C PFAM Glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,Phytase-like DYD2_k127_5863490_6 1237149.C900_04938 1.362e-52 188.0 COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,47NUW@768503|Cytophagia 976|Bacteroidetes G Belongs to the carbohydrate kinase PfkB family - - - - - - - - - - - - PfkB DYD2_k127_5869962_15 1237149.C900_02231 1.382e-129 421.0 COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,47JXF@768503|Cytophagia 976|Bacteroidetes M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 DYD2_k127_5869962_10 1237149.C900_02230 6.252e-166 533.0 COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,47KY0@768503|Cytophagia 976|Bacteroidetes M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD2_k127_5869962_26 1237149.C900_02229 4.399e-77 266.0 COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,47PU4@768503|Cytophagia 976|Bacteroidetes M Cell division protein ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ DYD2_k127_5869962_4 1237149.C900_02228 2.293e-236 735.0 COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,47K6I@768503|Cytophagia 976|Bacteroidetes D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA DYD2_k127_5869962_14 641524.ADICYQ_2547 6.576e-134 445.0 COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,47MUN@768503|Cytophagia 976|Bacteroidetes D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin DYD2_k127_5869962_18 700598.Niako_6535 8.082e-116 381.0 COG1647@1|root,COG1647@2|Bacteria,4NHPY@976|Bacteroidetes,1IQS4@117747|Sphingobacteriia 976|Bacteroidetes S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,BAAT_C,Hydrolase_4 DYD2_k127_5869962_21 1124780.ANNU01000024_gene3071 3.366e-96 320.0 COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia 976|Bacteroidetes M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 DYD2_k127_5869962_8 1237149.C900_02212 9.63e-181 577.0 COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,47MQR@768503|Cytophagia 976|Bacteroidetes O Membrane-bound serine protease (ClpP class) - - - ko:K07403 - - - - ko00000 - - - NfeD,Peptidase_S49,SDH_sah DYD2_k127_5869962_25 1237149.C900_02210 5.185e-78 272.0 COG1388@1|root,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,47NR5@768503|Cytophagia 976|Bacteroidetes M PFAM LysM domain lysM - - - - - - - - - - - ANF_receptor,LysM,Peripla_BP_6 DYD2_k127_5869962_19 1237149.C900_02209 2.363e-114 373.0 COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,47K0Q@768503|Cytophagia 976|Bacteroidetes L TIGRFAM TIGR02757 family protein - - - - - - - - - - - - DUF2400 DYD2_k127_5869962_22 1237149.C900_02208 1.776e-86 290.0 COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,47JX7@768503|Cytophagia 976|Bacteroidetes F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10,4.1.1.23 ko:K00762,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase,Pribosyltran DYD2_k127_5869962_28 1237149.C900_02207 2.796e-73 253.0 COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,47NQ9@768503|Cytophagia 976|Bacteroidetes F NUDIX domain - - - - - - - - - - - - NUDIX DYD2_k127_5869962_29 1237149.C900_02206 4.685e-71 242.0 COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,47PE3@768503|Cytophagia 976|Bacteroidetes H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD2_k127_5869962_20 1237149.C900_02205 7.025e-104 345.0 29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,47PSA@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3822) - - - - - - - - - - - - DUF3822 DYD2_k127_5869962_27 1237149.C900_02204 1.646e-75 261.0 2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,47NP8@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5869962_34 761193.Runsl_3776 2.012e-41 157.0 COG1051@1|root,COG1051@2|Bacteria,4NN73@976|Bacteroidetes,47P7Y@768503|Cytophagia 976|Bacteroidetes F Nudix hydrolase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX DYD2_k127_5869962_35 641524.ADICYQ_4319 4.75e-33 132.0 COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47QE9@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 DYD2_k127_5869962_36 1434325.AZQN01000002_gene758 4.234e-30 124.0 COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,47RJW@768503|Cytophagia 976|Bacteroidetes S small membrane protein - - - - - - - - - - - - DUF423 DYD2_k127_5869962_24 1237149.C900_02196 1.396e-79 271.0 COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,47M4Y@768503|Cytophagia 976|Bacteroidetes S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N DYD2_k127_5869962_3 1237149.C900_02195 1.073e-255 796.0 COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,47K42@768503|Cytophagia 976|Bacteroidetes IQ GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 DYD2_k127_5869962_32 1237149.C900_02194 1.07e-50 187.0 COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia 976|Bacteroidetes E PFAM Lysine exporter protein (LYSE YGGA) - - - - - - - - - - - - LysE DYD2_k127_5869962_12 1237149.C900_02193 9.686e-151 483.0 COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia 976|Bacteroidetes S PFAM von Willebrand factor type A batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA DYD2_k127_5869962_30 1237149.C900_02192 3.817e-69 244.0 2BPYJ@1|root,32ISF@2|Bacteria,4NRVJ@976|Bacteroidetes,47QN3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_5869962_13 1237149.C900_02191 5.818e-141 456.0 COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia 976|Bacteroidetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 DYD2_k127_5869962_38 1120968.AUBX01000018_gene2058 1.359e-16 84.0 2EK3P@1|root,33DU3@2|Bacteria,4NXK2@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4296) - - - - - - - - - - - - DUF4296 DYD2_k127_5869962_5 1237149.C900_02189 6.93e-231 738.0 COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,47KJ6@768503|Cytophagia 976|Bacteroidetes L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr DYD2_k127_5869962_31 929703.KE386491_gene672 1.874e-61 217.0 COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,47PDC@768503|Cytophagia 976|Bacteroidetes V PFAM ABC transporter - - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran DYD2_k127_5869962_16 1237149.C900_02185 2.641e-129 417.0 COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,47JJC@768503|Cytophagia 976|Bacteroidetes M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep DYD2_k127_5869962_2 1237149.C900_02184 1.782e-261 811.0 COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,47JFB@768503|Cytophagia 976|Bacteroidetes IM Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis fabZ - 3.5.1.108,4.2.1.59 ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 M00060,M00083 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 - - - FabA,LpxC DYD2_k127_5869962_11 1237149.C900_02183 5.01e-163 519.0 COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,47J9Z@768503|Cytophagia 976|Bacteroidetes M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD DYD2_k127_5869962_9 1237149.C900_02182 9.966e-178 565.0 COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,47JI5@768503|Cytophagia 976|Bacteroidetes S SMART Metal-dependent phosphohydrolase, HD region - - - ko:K06885 - - - - ko00000 - - - HD DYD2_k127_5869962_1 1237149.C900_02181 6.349e-262 814.0 COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,47KVF@768503|Cytophagia 976|Bacteroidetes T CheY-like receiver AAA-type ATPase and DNA-binding domains porX - - - - - - - - - - - PglZ,Response_reg DYD2_k127_5869962_33 1121481.AUAS01000007_gene924 3.104e-42 159.0 COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,47RDS@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised P-loop hydrolase UPF0079 yjeE - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE DYD2_k127_5869962_7 1237149.C900_02179 2.804e-199 627.0 COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47J94@768503|Cytophagia 976|Bacteroidetes E PFAM Alanine dehydrogenase PNT, C-terminal domain ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N DYD2_k127_5869962_0 1313301.AUGC01000003_gene2158 0.0 1272.0 COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes 976|Bacteroidetes J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 DYD2_k127_5869962_23 643867.Ftrac_0610 2.502e-80 281.0 COG2211@1|root,COG2211@2|Bacteria,4NTP1@976|Bacteroidetes,47UKC@768503|Cytophagia 976|Bacteroidetes G Major facilitator Superfamily - - - - - - - - - - - - - DYD2_k127_5869962_17 1408473.JHXO01000009_gene3374 2.394e-128 424.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,4NEV7@976|Bacteroidetes,2FKZX@200643|Bacteroidia 976|Bacteroidetes J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA DYD2_k127_5869962_6 1237149.C900_04904 2.74e-206 647.0 COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,47KTT@768503|Cytophagia 976|Bacteroidetes Q fumarylacetoacetate (FAA) hydrolase fahA - 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FAA_hydrolase,FAA_hydrolase_N DYD2_k127_590362_16 1237149.C900_04708 7.55e-170 542.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,47KJK@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD2_k127_590362_27 1237149.C900_04707 4.825e-110 366.0 COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,47NDQ@768503|Cytophagia 976|Bacteroidetes L Domain of unknown function (DUF4837) - - - - - - - - - - - - DUF4837 DYD2_k127_590362_2 1237149.C900_04706 0.0 1116.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,47JSR@768503|Cytophagia 976|Bacteroidetes C Phosphate acetyl butaryl transferase maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic DYD2_k127_590362_41 1237149.C900_04705 1.07e-69 241.0 COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,47N8D@768503|Cytophagia 976|Bacteroidetes L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N DYD2_k127_590362_0 1237149.C900_04704 0.0 2812.0 COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,47K4H@768503|Cytophagia 976|Bacteroidetes D Motility related/secretion protein sprA - - - - - - - - - - - SprA_N DYD2_k127_590362_46 1237149.C900_04703 9.749e-55 194.0 COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,47QD7@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H DYD2_k127_590362_19 1237149.C900_01774 8.369e-168 529.0 COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,47JGZ@768503|Cytophagia 976|Bacteroidetes H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM DYD2_k127_590362_39 643867.Ftrac_2749 1.765e-79 272.0 28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,47QT8@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_590362_34 1267211.KI669560_gene1008 4.779e-88 301.0 COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes 976|Bacteroidetes S phosphotransferase enzyme family mdsC - - - - - - - - - - - APH DYD2_k127_590362_30 866536.Belba_1158 2.035e-103 345.0 COG1209@1|root,COG1209@2|Bacteria,4NF32@976|Bacteroidetes,47K6F@768503|Cytophagia 976|Bacteroidetes M Nucleotidyl transferase - - - - - - - - - - - - NTP_transf_3,NTP_transferase DYD2_k127_590362_4 1048983.EL17_12315 7.219e-277 861.0 COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,47MV2@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF DYD2_k127_590362_23 1408813.AYMG01000025_gene2659 3.812e-119 392.0 COG1056@1|root,COG3172@1|root,COG1056@2|Bacteria,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1J0A0@117747|Sphingobacteriia 976|Bacteroidetes H ATPase kinase involved in NAD metabolism nadR - - - - - - - - - - - AAA_28 DYD2_k127_590362_32 1123277.KB893184_gene4128 4.493e-97 321.0 COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,47R6S@768503|Cytophagia 976|Bacteroidetes H TIGRFAM Nicotinamide mononucleotide transporter PnuC pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter DYD2_k127_590362_6 1237149.C900_03217 9.204e-249 773.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.32,1.2.1.85 ko:K00128,ko:K10217 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220 M00038,M00135,M00569 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_590362_28 468059.AUHA01000002_gene602 5.298e-104 344.0 COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1IRUS@117747|Sphingobacteriia 976|Bacteroidetes IQ PFAM Short-chain dehydrogenase reductase SDR - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_590362_36 1237149.C900_03219 1.88e-84 282.0 COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia 976|Bacteroidetes G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO DYD2_k127_590362_17 468059.AUHA01000003_gene1861 2.685e-169 541.0 COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1IQ2Y@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 DYD2_k127_590362_18 1237149.C900_03222 1.02e-168 541.0 COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47KM9@768503|Cytophagia 976|Bacteroidetes H Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid kmo - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD2_k127_590362_15 1237149.C900_03224 1.245e-177 569.0 COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,47NX6@768503|Cytophagia 976|Bacteroidetes M soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein mltF - - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT DYD2_k127_590362_25 1123248.KB893317_gene4295 5.422e-115 392.0 COG4775@1|root,COG4775@2|Bacteria,4NF38@976|Bacteroidetes,1IV5H@117747|Sphingobacteriia 976|Bacteroidetes M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - DYD2_k127_590362_47 1237149.C900_02852 1.621e-45 169.0 2E0QA@1|root,32W90@2|Bacteria,4NUC6@976|Bacteroidetes,47RSZ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_590362_11 925409.KI911562_gene307 8.64e-225 707.0 COG0069@1|root,COG0069@2|Bacteria,4NFKH@976|Bacteroidetes,1IREF@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the glutamate synthase family glt - - - - - - - - - - - Glu_synthase DYD2_k127_590362_13 485917.Phep_2341 2.665e-196 623.0 COG0579@1|root,COG0579@2|Bacteria,4NH56@976|Bacteroidetes,1IRCW@117747|Sphingobacteriia 976|Bacteroidetes C malate quinone oxidoreductase mqo - 1.1.5.4 ko:K00116 ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R00360,R00361,R01257 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Mqo DYD2_k127_590362_26 1122176.KB903537_gene1675 1.019e-113 373.0 COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,1IS7G@117747|Sphingobacteriia 976|Bacteroidetes S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 DYD2_k127_590362_43 1443665.JACA01000007_gene203 1.178e-60 219.0 COG0500@1|root,COG2226@2|Bacteria,4PH0U@976|Bacteroidetes,1IHRF@117743|Flavobacteriia,2YIT4@290174|Aquimarina 976|Bacteroidetes Q Hypothetical methyltransferase - - - - - - - - - - - - Methyltransf_11 DYD2_k127_590362_20 1453501.JELR01000002_gene443 1.422e-149 485.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,4657F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD2_k127_590362_53 1121904.ARBP01000001_gene5394 3.834e-15 85.0 292C5@1|root,2ZPWJ@2|Bacteria,4P7CG@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_590362_12 1122176.KB903543_gene589 2.23e-196 642.0 COG4206@1|root,COG4206@2|Bacteria,4PM6D@976|Bacteroidetes,1J101@117747|Sphingobacteriia 976|Bacteroidetes H Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_590362_48 1089547.KB913013_gene1126 6.522e-40 161.0 COG3712@1|root,COG3712@2|Bacteria,4NMA2@976|Bacteroidetes,47PEK@768503|Cytophagia 976|Bacteroidetes PT Domain of unknown function (DUF4974) - - - - - - - - - - - - DUF4974,FecR DYD2_k127_590362_49 1168034.FH5T_15740 6.933e-38 148.0 COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,2FSZY@200643|Bacteroidia 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_590362_3 1250232.JQNJ01000001_gene3410 4.015e-279 876.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 DYD2_k127_590362_21 1239962.C943_03438 1.025e-143 469.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase,Glyoxalase_2 DYD2_k127_590362_45 1121481.AUAS01000002_gene3264 1.287e-58 210.0 28PRQ@1|root,2ZCDG@2|Bacteria,4NWY7@976|Bacteroidetes,47SAI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_590362_51 1279009.ADICEAN_02532 3.735e-22 100.0 COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,47RW5@768503|Cytophagia 976|Bacteroidetes C Acylphosphatase acyP - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase DYD2_k127_590362_5 1144325.PMI22_03563 1.115e-251 785.0 COG1012@1|root,COG1012@2|Bacteria,1R3TA@1224|Proteobacteria,1S021@1236|Gammaproteobacteria 1236|Gammaproteobacteria C aldehyde gapN - 1.2.1.9 ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 M00308,M00633 R01058 RC00242 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_590362_38 1237149.C900_02850 1.1e-80 275.0 COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,47NPE@768503|Cytophagia 976|Bacteroidetes F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC DYD2_k127_590362_44 1237149.C900_00497 1.617e-60 229.0 COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes 976|Bacteroidetes S tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_8 DYD2_k127_590362_8 1124780.ANNU01000035_gene276 3.697e-243 756.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47JS2@768503|Cytophagia 976|Bacteroidetes C dihydrolipoamide dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim DYD2_k127_590362_22 1237149.C900_00485 1.655e-127 411.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,47MF7@768503|Cytophagia 976|Bacteroidetes IQ TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_590362_50 649349.Lbys_0654 9.039e-24 106.0 COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,47NZT@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 DYD2_k127_590362_9 1237149.C900_01800 5.121e-240 746.0 COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,47M8Z@768503|Cytophagia 976|Bacteroidetes E PFAM Cys Met metabolism PLP-dependent enzyme metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP DYD2_k127_590362_24 926549.KI421517_gene1840 1.488e-117 387.0 COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,47KMZ@768503|Cytophagia 976|Bacteroidetes E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metXA - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD2_k127_590362_33 1313421.JHBV01000032_gene1573 2.452e-95 326.0 COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1IPM4@117747|Sphingobacteriia 976|Bacteroidetes E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - Homoserine_dh,NAD_binding_3 DYD2_k127_590362_7 1124780.ANNU01000051_gene2071 5.633e-247 766.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,47NPF@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway nqrF - 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 DYD2_k127_590362_31 886377.Murru_2374 1.492e-99 335.0 2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,1I0KC@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - Phenol_MetA_deg DYD2_k127_590362_14 1237149.C900_01796 9.032e-179 566.0 COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,47JES@768503|Cytophagia 976|Bacteroidetes E Belongs to the arginase family - - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD2_k127_590362_42 1380600.AUYN01000001_gene2387 9.823e-68 238.0 28JI1@1|root,2Z9BG@2|Bacteria,4NMDW@976|Bacteroidetes,1I1PA@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_590362_29 1237149.C900_01808 1.633e-103 344.0 COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,47JXA@768503|Cytophagia 976|Bacteroidetes S PFAM YicC-like family, N-terminal region - - - - - - - - - - - - DUF1732,YicC_N DYD2_k127_590362_1 1237149.C900_01809 0.0 1229.0 COG0823@1|root,COG0823@2|Bacteria,4PNV1@976|Bacteroidetes,47YIP@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 DYD2_k127_590362_35 1123057.P872_25285 8.972e-88 301.0 COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia 976|Bacteroidetes E PFAM FAD dependent oxidoreductase thiO - - - - - - - - - - - DAO DYD2_k127_590362_37 1123057.P872_25280 5.763e-84 284.0 COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia 976|Bacteroidetes P PFAM Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD2_k127_590362_40 1237149.C900_01812 1.204e-72 251.0 COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia 976|Bacteroidetes I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD2_k127_590362_10 1237149.C900_01813 4.426e-227 727.0 COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia 976|Bacteroidetes S Peptidase family C25 porU - - - - - - - - - - - Peptidase_C25 DYD2_k127_5951501_0 1237149.C900_01193 5.795e-103 343.0 COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,47KM1@768503|Cytophagia 976|Bacteroidetes D Belongs to the ABC-4 integral membrane protein family. FtsX subfamily ftsX GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX DYD2_k127_5951501_3 1048983.EL17_08650 9.148e-19 87.0 2DQ4W@1|root,334SC@2|Bacteria,4NUQX@976|Bacteroidetes,47RZV@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3098) - - - - - - - - - - - - DUF3098 DYD2_k127_5951501_1 313606.M23134_01055 8.464e-100 331.0 COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia 976|Bacteroidetes V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA DYD2_k127_5951501_2 1237149.C900_01190 2.367e-55 197.0 COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,47P98@768503|Cytophagia 976|Bacteroidetes J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C_2,TruB_N DYD2_k127_5953155_17 1127673.GLIP_3419 2.287e-05 46.0 COG2931@1|root,COG4935@1|root,COG2931@2|Bacteria,COG4935@2|Bacteria,1NJV7@1224|Proteobacteria,1RN7Q@1236|Gammaproteobacteria,465ZC@72275|Alteromonadaceae 1236|Gammaproteobacteria O Metallo-peptidase family M12B Reprolysin-like - - - - - - - - - - - - Reprolysin_4 DYD2_k127_5953155_14 1163398.AJJP01000190_gene4270 2.291e-20 105.0 COG2931@1|root,COG3209@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,1MU7T@1224|Proteobacteria 1224|Proteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Cadherin_3,DUF4347,HemolysinCabind DYD2_k127_5953155_8 1313421.JHBV01000052_gene192 2.117e-68 251.0 COG3209@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5384@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5384@2|Bacteria,4PPW2@976|Bacteroidetes,1J12N@117747|Sphingobacteriia 2|Bacteria JMU domain protein - - 3.2.1.4 ko:K01179,ko:K19360,ko:K21449 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko02000,ko03036 1.B.40.2 GH5,GH9 - FIVAR,LRR_5,Phospholip_A2_3 DYD2_k127_5953155_10 1122179.KB890457_gene2083 1.627e-48 179.0 COG1416@1|root,COG1416@2|Bacteria,4NVVJ@976|Bacteroidetes,1IYQX@117747|Sphingobacteriia 976|Bacteroidetes S DsrE/DsrF-like family - - - - - - - - - - - - DrsE DYD2_k127_5953155_4 1123277.KB893228_gene2151 1.96e-138 447.0 COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,47K8J@768503|Cytophagia 976|Bacteroidetes H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM DYD2_k127_5953155_15 929556.Solca_1995 2.914e-19 90.0 COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes,1IZEY@117747|Sphingobacteriia 976|Bacteroidetes H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS DYD2_k127_5953155_11 1121904.ARBP01000005_gene4463 8.45e-45 166.0 COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,47QJT@768503|Cytophagia 976|Bacteroidetes H Molybdopterin converting factor, large subunit moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE DYD2_k127_5953155_12 929562.Emtol_2310 6.776e-38 149.0 COG0746@1|root,COG0746@2|Bacteria,4NMYW@976|Bacteroidetes,47NQP@768503|Cytophagia 976|Bacteroidetes H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD2_k127_5953155_9 760192.Halhy_1974 4.661e-55 196.0 COG0315@1|root,COG0315@2|Bacteria,4NHA0@976|Bacteroidetes,1ISV2@117747|Sphingobacteriia 976|Bacteroidetes H Molybdenum cofactor biosynthesis protein moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC DYD2_k127_5953155_6 1185876.BN8_01302 4.949e-129 423.0 COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,47M8R@768503|Cytophagia 976|Bacteroidetes H Molybdenum cofactor synthesis domain protein moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N DYD2_k127_5953155_7 580331.Thit_1449 1.414e-99 337.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,42EMH@68295|Thermoanaerobacterales 186801|Clostridia G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase DYD2_k127_5953155_1 1237149.C900_04390 7.539e-223 696.0 COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,47MYD@768503|Cytophagia 976|Bacteroidetes U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB DYD2_k127_5953155_13 1237149.C900_04900 1.908e-37 145.0 COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia 976|Bacteroidetes O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease DYD2_k127_5953155_2 313606.M23134_02382 2.67e-159 505.0 COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,47KJX@768503|Cytophagia 976|Bacteroidetes HJ Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK DYD2_k127_5953155_5 1121904.ARBP01000002_gene7256 2.805e-137 443.0 COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,47KAM@768503|Cytophagia 976|Bacteroidetes S PFAM Succinylglutamate desuccinylase Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA DYD2_k127_5953155_3 1237149.C900_01598 4.999e-153 490.0 COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia 976|Bacteroidetes P TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF DYD2_k127_5953155_0 1237149.C900_01599 4.12e-228 746.0 COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD DYD2_k127_5953155_16 1313421.JHBV01000039_gene2759 3.735e-06 61.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NFMW@976|Bacteroidetes,1IW54@117747|Sphingobacteriia 976|Bacteroidetes O SPTR Peptidase S8 and S53 subtilisin kexin sedolisin - - - - - - - - - - - - CARDB,MAM,PKD,Peptidase_S8 DYD2_k127_6028818_17 985255.APHJ01000035_gene9 3.335e-18 85.0 COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1HZY7@117743|Flavobacteriia,2P616@244698|Gillisia 976|Bacteroidetes PQ Peptidase family S51 cphB - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 DYD2_k127_6028818_6 865937.Gilli_2639 8.539e-135 435.0 COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia,2P61W@244698|Gillisia 976|Bacteroidetes E Asparaginase ybiK - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 DYD2_k127_6028818_2 1150600.ADIARSV_0365 3.981e-179 568.0 COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP DYD2_k127_6028818_3 1237149.C900_04328 4.358e-147 469.0 COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,47KE8@768503|Cytophagia 976|Bacteroidetes F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt DYD2_k127_6028818_14 1279009.ADICEAN_01481 9.186e-53 198.0 28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,47SGM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6028818_10 1237149.C900_00456 2.151e-108 354.0 COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia 976|Bacteroidetes I Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159 DYD2_k127_6028818_9 1237149.C900_01420 1.157e-109 367.0 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia 976|Bacteroidetes O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ccmG - - - - - - - - - - - AhpC-TSA,DUF4369 DYD2_k127_6028818_1 1237149.C900_01419 5.43e-215 676.0 COG0064@1|root,COG0064@2|Bacteria,4NF3B@976|Bacteroidetes,47K7E@768503|Cytophagia 976|Bacteroidetes J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey DYD2_k127_6028818_0 1237149.C900_01418 0.0 1183.0 COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,47KKH@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD2_k127_6028818_13 1237149.C900_01417 4.62e-62 225.0 COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes 976|Bacteroidetes M peptidase M23 - - - - - - - - - - - - Peptidase_M23 DYD2_k127_6028818_11 1237149.C900_01416 8.661e-86 294.0 COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD2_k127_6028818_5 1237149.C900_01411 5.025e-136 443.0 COG2843@1|root,COG2843@2|Bacteria,4NI6J@976|Bacteroidetes,47NKK@768503|Cytophagia 976|Bacteroidetes M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap DYD2_k127_6028818_15 643867.Ftrac_2908 2.607e-49 178.0 COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,47QJY@768503|Cytophagia 976|Bacteroidetes K transcriptional regulator ycgE - - - - - - - - - - - MerR_1 DYD2_k127_6028818_4 1237149.C900_01409 2.663e-137 446.0 COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,47M2T@768503|Cytophagia 976|Bacteroidetes LU TIGRFAM DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A,HHH_5 DYD2_k127_6028818_8 1237149.C900_01378 2.754e-117 383.0 COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,47KB5@768503|Cytophagia 976|Bacteroidetes E Isopropylmalate homocitrate citramalate synthase mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like DYD2_k127_6028818_18 1237149.C900_01377 3.935e-17 82.0 COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47NYP@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 DYD2_k127_6028818_16 1237149.C900_01374 7.514e-20 92.0 2C85B@1|root,2ZAAM@2|Bacteria,4NKNU@976|Bacteroidetes,47P2W@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6028818_7 1237149.C900_02483 1.008e-119 393.0 COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,47KJJ@768503|Cytophagia 976|Bacteroidetes M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C DYD2_k127_6028818_12 1237149.C900_02480 1.99e-83 278.0 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia 976|Bacteroidetes F PFAM Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 DYD2_k127_6030338_3 1123057.P872_15440 9.444e-17 81.0 COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia 976|Bacteroidetes S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 DYD2_k127_6030338_1 1123057.P872_11925 4.309e-59 211.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,47QK5@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 DYD2_k127_6030338_2 1131812.JQMS01000001_gene3047 6.176e-32 130.0 2E32S@1|root,32Y2Z@2|Bacteria,4NW5U@976|Bacteroidetes,1IANV@117743|Flavobacteriia,2NWTF@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6030338_0 391596.PBAL39_07500 5.589e-96 325.0 COG1295@1|root,COG1295@2|Bacteria,4NFG8@976|Bacteroidetes,1IQ97@117747|Sphingobacteriia 976|Bacteroidetes S TIGRFAM YihY family protein (not ribonuclease BN) - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB DYD2_k127_6036628_4 391587.KAOT1_16763 2.135e-06 52.0 2B2RR@1|root,2Z9ZD@2|Bacteria,4NKN4@976|Bacteroidetes,1II67@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6036628_0 643867.Ftrac_3380 3.536e-95 316.0 COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes,47N83@768503|Cytophagia 976|Bacteroidetes K Crp-like helix-turn-helix domain - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding DYD2_k127_6036628_2 1120968.AUBX01000017_gene1882 2.982e-79 273.0 COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,47PMH@768503|Cytophagia 976|Bacteroidetes S beta barrel domain - - - ko:K07140 - - - - ko00000 - - - MOSC,MOSC_N DYD2_k127_6036628_1 1237149.C900_00531 1.637e-81 276.0 COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47NK1@768503|Cytophagia 976|Bacteroidetes S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD2_k127_6036628_3 643867.Ftrac_3377 2.571e-40 153.0 COG2010@1|root,COG2010@2|Bacteria,4NTWV@976|Bacteroidetes,47REP@768503|Cytophagia 976|Bacteroidetes C Cytochrome c, class I aniA - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD2_k127_6062118_3 1237149.C900_05827 0.0 1015.0 COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,47JS9@768503|Cytophagia 976|Bacteroidetes L Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD2_k127_6062118_0 1237149.C900_05830 0.0 1270.0 COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,47JQZ@768503|Cytophagia 976|Bacteroidetes L Belongs to the type II topoisomerase GyrA ParC subunit family parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_topoisoIV DYD2_k127_6062118_18 1121904.ARBP01000002_gene7268 3.852e-25 111.0 2BZCX@1|root,33XUD@2|Bacteria,4P3BB@976|Bacteroidetes,47V4G@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6062118_12 1237149.C900_05831 1.201e-70 246.0 COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes,47QCV@768503|Cytophagia 976|Bacteroidetes J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD2_k127_6062118_13 1237149.C900_05832 6.43e-69 240.0 COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,47MWP@768503|Cytophagia 976|Bacteroidetes S DUF218 domain - - - ko:K03748 - - - - ko00000 - - - DUF218 DYD2_k127_6062118_1 1237149.C900_05833 0.0 1065.0 COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MA1@768503|Cytophagia 976|Bacteroidetes M CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 DYD2_k127_6062118_2 1237149.C900_05835 0.0 1058.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,47MA2@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD DYD2_k127_6062118_11 1279009.ADICEAN_00395 2.218e-78 265.0 COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,47PC6@768503|Cytophagia 976|Bacteroidetes J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N DYD2_k127_6062118_22 1237149.C900_05837 5.31e-18 85.0 COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,47RYG@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p DYD2_k127_6062118_15 1218108.KB908306_gene255 7.312e-56 196.0 COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia 976|Bacteroidetes J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 DYD2_k127_6062118_25 1189612.A33Q_1263 2.55e-08 57.0 2DDKA@1|root,2ZIEQ@2|Bacteria,4P85D@976|Bacteroidetes,47WRH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6062118_23 313598.MED152_13344 2.271e-16 83.0 COG2010@1|root,COG2010@2|Bacteria,4NWPQ@976|Bacteroidetes,1IN2Q@117743|Flavobacteriia,3VWUB@52959|Polaribacter 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - - DYD2_k127_6062118_16 1237149.C900_01970 5.665e-47 174.0 COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI DYD2_k127_6062118_10 1237149.C900_01971 3.6e-88 300.0 COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - DYD2_k127_6062118_6 760192.Halhy_2614 7.399e-152 492.0 COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,1IZ8B@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307,ko:K14387 ko04725,ko05231,map04725,map05231 - - - ko00000,ko00001,ko02000 2.A.21,2.A.21.8 - - HD_4,SSF DYD2_k127_6062118_21 1380387.JADM01000018_gene3381 9.725e-20 94.0 COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1XKAV@135619|Oceanospirillales 135619|Oceanospirillales O redox protein, regulator of disulfide bond formation - - - ko:K07397 - - - - ko00000 - - - OsmC DYD2_k127_6062118_4 1237149.C900_05467 1.678e-192 607.0 COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia 976|Bacteroidetes E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP DYD2_k127_6062118_7 1237149.C900_01348 7.753e-142 459.0 COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia 976|Bacteroidetes H MoeZ MoeB domain moeZ - 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF DYD2_k127_6062118_5 1237149.C900_01349 1.456e-191 604.0 COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,47JS1@768503|Cytophagia 976|Bacteroidetes S PFAM FAD dependent oxidoreductase lhgO - - ko:K15736 - - - - ko00000,ko01000 - - - DAO DYD2_k127_6062118_9 1237149.C900_03711 1.543e-94 318.0 COG0121@1|root,COG0121@2|Bacteria 2|Bacteria S cellular modified histidine biosynthetic process egtC - - ko:K18802 - - - - ko00000 - - - GATase_4 DYD2_k127_6062118_14 1237149.C900_01352 1.418e-62 219.0 COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,47PZ4@768503|Cytophagia 976|Bacteroidetes O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR DYD2_k127_6062118_17 760192.Halhy_5296 2e-25 113.0 2CH44@1|root,32S57@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_6062118_19 1123037.AUDE01000019_gene3304 5.397e-22 98.0 2E3D8@1|root,32YCF@2|Bacteria,4NUPM@976|Bacteroidetes,1I544@117743|Flavobacteriia 976|Bacteroidetes S MerR HTH family regulatory protein - - - - - - - - - - - - MerR_2 DYD2_k127_6062118_8 1178825.ALIH01000006_gene1560 1.613e-123 400.0 COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1HXJ8@117743|Flavobacteriia 976|Bacteroidetes O molecular chaperone dnaJ2 - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C DYD2_k127_609503_13 1237149.C900_03797 1.088e-113 381.0 COG4252@1|root,COG4252@2|Bacteria,4NMM6@976|Bacteroidetes,47PFU@768503|Cytophagia 976|Bacteroidetes T CHASE2 domain - - - - - - - - - - - - CHASE2 DYD2_k127_609503_16 1237149.C900_03796 4.881e-80 276.0 2BHR8@1|root,32BUM@2|Bacteria,4NR4P@976|Bacteroidetes,47QNP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_609503_8 1124780.ANNU01000054_gene3524 1.479e-159 505.0 COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,47K03@768503|Cytophagia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA,Succ_CoA_lig DYD2_k127_609503_3 1237149.C900_00716 2.227e-237 739.0 COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia 976|Bacteroidetes T PIN domain ybeZ_1 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH DYD2_k127_609503_1 1121957.ATVL01000007_gene1691 3.729e-240 750.0 COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,47JD2@768503|Cytophagia 976|Bacteroidetes H magnesium chelatase chlI - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - AAA_5,Sigma54_activat DYD2_k127_609503_5 1237149.C900_00713 5.868e-191 601.0 COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,47K13@768503|Cytophagia 976|Bacteroidetes S von Willebrand factor, type A - - - - - - - - - - - - VWA_2 DYD2_k127_609503_14 1237149.C900_00710 9.732e-87 292.0 COG3000@1|root,COG3000@2|Bacteria,4NMV7@976|Bacteroidetes,47PA0@768503|Cytophagia 976|Bacteroidetes I Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase DYD2_k127_609503_6 1237149.C900_00709 4.069e-190 599.0 COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,47JT9@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 DYD2_k127_609503_0 1237149.C900_00708 1.786e-273 871.0 COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47K15@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 3 N terminal domain - - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C DYD2_k127_609503_19 1237149.C900_00707 7.5e-17 84.0 2E1YR@1|root,32X7B@2|Bacteria,4NUBX@976|Bacteroidetes,47R5A@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_609503_2 1237149.C900_00706 2.054e-239 754.0 COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,47KZU@768503|Cytophagia 976|Bacteroidetes L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C DYD2_k127_609503_17 1237149.C900_00705 7.867e-52 189.0 COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,47PBZ@768503|Cytophagia 976|Bacteroidetes S PFAM Rhomboid family - - 3.4.21.105 ko:K09650 - - - - ko00000,ko01000,ko01002,ko03029 - - - Rhomboid DYD2_k127_609503_12 1237149.C900_00704 1.657e-117 384.0 COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,47JAM@768503|Cytophagia 976|Bacteroidetes S PFAM Rhomboid family - - - - - - - - - - - - Rhomboid DYD2_k127_609503_4 1239962.C943_03619 1.154e-196 620.0 COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes,47P29@768503|Cytophagia 976|Bacteroidetes E Cys/Met metabolism PLP-dependent enzyme - - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP DYD2_k127_609503_15 929562.Emtol_3547 4.494e-84 287.0 COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,47M4I@768503|Cytophagia 976|Bacteroidetes S VIT family - - - - - - - - - - - - VIT1 DYD2_k127_609503_7 1237149.C900_05878 1.399e-171 544.0 COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,47KHN@768503|Cytophagia 976|Bacteroidetes J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM DYD2_k127_609503_11 1121904.ARBP01000007_gene3097 1.8e-133 434.0 COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,47NP1@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N DYD2_k127_609503_10 1121904.ARBP01000006_gene4066 5.589e-135 438.0 COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47N8Q@768503|Cytophagia 976|Bacteroidetes M mandelate racemase muconate lactonizing - - - - - - - - - - - - MR_MLE_C,MR_MLE_N DYD2_k127_609503_18 525373.HMPREF0766_10288 8.034e-29 123.0 COG0526@1|root,COG0526@2|Bacteria,4NUZ2@976|Bacteroidetes,1IU3I@117747|Sphingobacteriia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA DYD2_k127_609503_9 929562.Emtol_3064 3.657e-143 465.0 COG0526@1|root,COG0526@2|Bacteria,4PNAP@976|Bacteroidetes,47YAI@768503|Cytophagia 976|Bacteroidetes CO Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - - - - - - - - - - Cu2_monoox_C DYD2_k127_609503_20 1237149.C900_03811 8.467e-11 65.0 COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes 976|Bacteroidetes HP abc transporter (atp-binding protein) - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran DYD2_k127_6103620_3 153721.MYP_1259 6.825e-32 126.0 COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,47R5P@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 DYD2_k127_6103620_0 1237149.C900_01735 2.572e-182 595.0 COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,47MFU@768503|Cytophagia 976|Bacteroidetes Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS DYD2_k127_6103620_1 1237149.C900_01734 2.951e-164 527.0 COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,47MCP@768503|Cytophagia 976|Bacteroidetes M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD2_k127_6103620_2 1121904.ARBP01000004_gene849 2.514e-61 219.0 COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,47J8W@768503|Cytophagia 976|Bacteroidetes S TIGRFAM TIGR02453 family protein - - - - - - - - - - - - DUF2461 DYD2_k127_6103620_4 1237149.C900_00374 8.401e-16 85.0 COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria 2|Bacteria T photoreceptor activity - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9,Reg_prop,Response_reg,STAS,Y_Y_Y DYD2_k127_6108285_3 869213.JCM21142_72830 9.398e-72 245.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD2_k127_6108285_0 761193.Runsl_5035 3.148e-171 546.0 COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M80@768503|Cytophagia 976|Bacteroidetes L Belongs to the DEAD box helicase family deaD - - - - - - - - - - - DEAD,Helicase_C DYD2_k127_6108285_5 1408473.JHXO01000006_gene1325 1.984e-26 109.0 COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,2FYPS@200643|Bacteroidia 976|Bacteroidetes K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD2_k127_6108285_2 1237149.C900_01855 2.462e-133 428.0 COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,47KJ0@768503|Cytophagia 976|Bacteroidetes I fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase DYD2_k127_6108285_4 1237149.C900_01856 9.774e-55 198.0 COG1595@1|root,COG1595@2|Bacteria,4P4V9@976|Bacteroidetes,47XV7@768503|Cytophagia 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_6108285_1 1279009.ADICEAN_02685 5.392e-171 542.0 COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,47MKS@768503|Cytophagia 976|Bacteroidetes E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD2_k127_6146521_0 1237149.C900_04864 5.799e-169 536.0 COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,47JMH@768503|Cytophagia 976|Bacteroidetes L PFAM UvrD REP helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD2_k127_6146521_2 1237149.C900_04865 5.046e-67 235.0 28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,47PZX@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4290) - - - - - - - - - - - - DUF4290 DYD2_k127_6146521_1 153721.MYP_2209 5.409e-117 380.0 COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,47JQ7@768503|Cytophagia 976|Bacteroidetes M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase DYD2_k127_617992_24 1121104.AQXH01000001_gene1479 1.621e-17 84.0 2EHC3@1|root,33B3Y@2|Bacteria,4NZPQ@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 DYD2_k127_617992_26 1267211.KI669560_gene1771 4.887e-10 70.0 2BG4X@1|root,33858@2|Bacteria,4NW0E@976|Bacteroidetes,1IUAK@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 DYD2_k127_617992_1 1166018.FAES_pFAES01022 3.17e-258 816.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47MDX@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD2_k127_617992_12 1237149.C900_00102 9.92e-72 246.0 COG1595@1|root,COG1595@2|Bacteria,4NKHT@976|Bacteroidetes,47P68@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_617992_14 471854.Dfer_3557 5.149e-64 225.0 COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,47N8U@768503|Cytophagia 976|Bacteroidetes S PFAM Rhomboid family - - - - - - - - - - - - Rhomboid DYD2_k127_617992_13 1279009.ADICEAN_04058 4.039e-71 250.0 COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47K8M@768503|Cytophagia 976|Bacteroidetes O Domain amino terminal to FKBP-type peptidyl-prolyl isomerase fklB - 5.2.1.8 ko:K03772,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N DYD2_k127_617992_22 378806.STAUR_1557 5.442e-26 121.0 COG2220@1|root,COG2220@2|Bacteria 2|Bacteria S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - - - - - - - - - - Lactamase_B_3 DYD2_k127_617992_0 1237149.C900_02686 0.0 1274.0 COG1643@1|root,COG1643@2|Bacteria,4NFJ7@976|Bacteroidetes,47KRZ@768503|Cytophagia 976|Bacteroidetes L DEAD DEAH box helicase - - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C DYD2_k127_617992_18 1484460.JSWG01000009_gene529 1.113e-48 184.0 COG1501@1|root,COG2819@1|root,COG1501@2|Bacteria,COG2819@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31 DYD2_k127_617992_5 1121904.ARBP01000011_gene1450 2.647e-163 521.0 COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,47NGE@768503|Cytophagia 976|Bacteroidetes S Pirin C-terminal cupin domain - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C DYD2_k127_617992_21 1237149.C900_05048 3.509e-29 123.0 COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,47XV8@768503|Cytophagia 976|Bacteroidetes O Hsp20/alpha crystallin family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD2_k127_617992_27 398720.MED217_05662 5.062e-08 56.0 28XWV@1|root,2ZJT0@2|Bacteria,4P9A9@976|Bacteroidetes,1IBUT@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_617992_15 1121285.AUFK01000011_gene409 3.378e-54 193.0 COG0454@1|root,COG0456@2|Bacteria,4NQCD@976|Bacteroidetes,1I3A0@117743|Flavobacteriia,3ZRQ7@59732|Chryseobacterium 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD2_k127_617992_4 1121904.ARBP01000010_gene2295 3.679e-172 556.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia 976|Bacteroidetes Q PFAM D-aminoacylase, C-terminal region - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 DYD2_k127_617992_10 861299.J421_6340 8.136e-81 276.0 COG1028@1|root,COG1028@2|Bacteria,1ZTIT@142182|Gemmatimonadetes 142182|Gemmatimonadetes IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD2_k127_617992_20 861299.J421_6341 1.048e-31 127.0 COG1917@1|root,COG1917@2|Bacteria,1ZTY8@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_617992_16 1336803.PHEL49_1566 1.824e-49 184.0 COG1357@1|root,COG1357@2|Bacteria,4NR89@976|Bacteroidetes,1I76A@117743|Flavobacteriia,3VV8X@52959|Polaribacter 976|Bacteroidetes S Pentapeptide repeats (9 copies) - - - - - - - - - - - - Pentapeptide_3 DYD2_k127_617992_3 1122176.KB903560_gene3555 3.017e-229 731.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPMK@117747|Sphingobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 DYD2_k127_617992_11 760192.Halhy_3288 1.083e-74 261.0 COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1IRHE@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Bacterial lipid A biosynthesis acyltransferase waaM - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD2_k127_617992_8 1237149.C900_04112 1.385e-96 320.0 COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,47PCP@768503|Cytophagia 976|Bacteroidetes P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA DYD2_k127_617992_2 468059.AUHA01000002_gene1342 5.993e-233 731.0 COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1IWEW@117747|Sphingobacteriia 976|Bacteroidetes P Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - Sulfate_transp DYD2_k127_617992_6 221288.JH992901_gene3895 1.059e-161 518.0 COG0715@1|root,COG0715@2|Bacteria,1GFIM@1117|Cyanobacteria 1117|Cyanobacteria P Protein of unknown function (DUF3500) - - - - - - - - - - - - DUF3500 DYD2_k127_617992_7 1121104.AQXH01000004_gene39 8.712e-105 348.0 COG4242@1|root,COG4242@2|Bacteria,4NHDE@976|Bacteroidetes,1IWDD@117747|Sphingobacteriia 976|Bacteroidetes PQ Peptidase family S51 - - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 DYD2_k127_617992_17 1121875.KB907552_gene295 4.147e-49 183.0 2DMXX@1|root,32UAZ@2|Bacteria,4NUGJ@976|Bacteroidetes,1I4U9@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_617992_25 345219.Bcoa_3258 6.559e-16 81.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD2_k127_617992_23 391587.KAOT1_02877 3.143e-19 93.0 2E6Q3@1|root,331AC@2|Bacteria,4NUP2@976|Bacteroidetes,1I4Z6@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF5362 DYD2_k127_617992_9 926566.Terro_1276 1.992e-95 339.0 COG1363@1|root,COG1363@2|Bacteria,3Y2Y3@57723|Acidobacteria,2JKCI@204432|Acidobacteriia 204432|Acidobacteriia G PFAM M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 DYD2_k127_6185439_0 234267.Acid_0997 4.563e-142 459.0 COG0318@1|root,COG0318@2|Bacteria 2|Bacteria IQ PFAM AMP-dependent synthetase and ligase fadD36 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - ko:K12429,ko:K18660,ko:K18661,ko:K18662 ko00280,map00280 - R03383 RC00004,RC00137 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C DYD2_k127_6185439_2 1499967.BAYZ01000013_gene6434 6.72e-89 302.0 COG0329@1|root,COG0329@2|Bacteria 2|Bacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD2_k127_6185439_1 1121904.ARBP01000016_gene5280 1.451e-116 378.0 COG0075@1|root,COG0075@2|Bacteria,4NH61@976|Bacteroidetes,47VRP@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K03430 ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R04152 RC00006,RC00008,RC00018,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD2_k127_618645_3 411477.PARMER_01267 5.855e-18 85.0 COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,2FT2E@200643|Bacteroidia,22Y4Y@171551|Porphyromonadaceae 976|Bacteroidetes M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL DYD2_k127_618645_1 926549.KI421517_gene3436 2.784e-141 454.0 COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N DYD2_k127_618645_2 929703.KE386491_gene2893 8.328e-22 100.0 2C5P8@1|root,32U6D@2|Bacteria,4NSY7@976|Bacteroidetes,47R86@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_618645_0 1237149.C900_05825 6.043e-160 513.0 COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,47KXY@768503|Cytophagia 976|Bacteroidetes I PFAM Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase DYD2_k127_6230405_3 866536.Belba_1168 3.153e-70 245.0 COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,47NI9@768503|Cytophagia 976|Bacteroidetes O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK DYD2_k127_6230405_4 1237149.C900_01722 1.072e-66 235.0 COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K36@768503|Cytophagia 976|Bacteroidetes H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase DYD2_k127_6230405_2 1237149.C900_01723 1.276e-113 380.0 COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,47N37@768503|Cytophagia 976|Bacteroidetes I membrane - - - - - - - - - - - - - DYD2_k127_6230405_1 1237149.C900_01724 8.818e-126 416.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,47MJ6@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat protein - - - - - - - - - - - - TPR_8 DYD2_k127_6230405_5 1237149.C900_01725 6.658e-51 186.0 COG3117@1|root,COG3117@2|Bacteria,4NRIN@976|Bacteroidetes,47R6J@768503|Cytophagia 976|Bacteroidetes S Lipopolysaccharide-assembly, LptC-related - - - - - - - - - - - - LptC DYD2_k127_6230405_0 643867.Ftrac_2007 9.994e-167 533.0 COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,47KQX@768503|Cytophagia 976|Bacteroidetes S CBS domain tlyC - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 DYD2_k127_6230405_6 1237149.C900_01727 1.434e-35 139.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,47KBN@768503|Cytophagia 976|Bacteroidetes O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_2 DYD2_k127_6233963_2 1237149.C900_02626 1.386e-225 704.0 COG1012@1|root,COG1012@2|Bacteria 2|Bacteria C belongs to the aldehyde dehydrogenase family paaN - - - - - - - - - - - Aldedh DYD2_k127_6233963_10 1237149.C900_02624 3.374e-101 334.0 2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,47P85@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 DYD2_k127_6233963_5 1237149.C900_02623 7.93e-166 531.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,47JN4@768503|Cytophagia 976|Bacteroidetes S CinA-like protein cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth DYD2_k127_6233963_1 395493.BegalDRAFT_1564 0.0 1281.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,460EP@72273|Thiotrichales 72273|Thiotrichales G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N DYD2_k127_6233963_4 926556.Echvi_2446 8.171e-179 569.0 COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,47JDY@768503|Cytophagia 976|Bacteroidetes C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bfmBB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD2_k127_6233963_11 760192.Halhy_1095 4.037e-33 144.0 COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,1ITGY@117747|Sphingobacteriia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,TPR_12,TPR_7,TPR_8 DYD2_k127_6233963_3 1124780.ANNU01000061_gene906 8.375e-186 587.0 COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,47JY2@768503|Cytophagia 976|Bacteroidetes E PFAM Cys Met metabolism PLP-dependent enzyme metC - 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP DYD2_k127_6233963_12 420662.Mpe_A3768 1.987e-10 65.0 2EIBB@1|root,313DD@2|Bacteria,1NEYC@1224|Proteobacteria,2WCBT@28216|Betaproteobacteria,1KP5C@119065|unclassified Burkholderiales 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD2_k127_6233963_6 926549.KI421517_gene109 3.646e-164 526.0 COG0477@1|root,COG2814@2|Bacteria,4NEQU@976|Bacteroidetes,47KKT@768503|Cytophagia 976|Bacteroidetes EGP Major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1 DYD2_k127_6233963_0 1237149.C900_02615 0.0 1525.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_6233963_13 588596.U9SUP0 1.629e-05 48.0 2E5UP@1|root,2SCKV@2759|Eukaryota,3A8RK@33154|Opisthokonta,3P77N@4751|Fungi 4751|Fungi S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N DYD2_k127_6233963_9 1237149.C900_02612 5.185e-114 376.0 COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,47NTZ@768503|Cytophagia 976|Bacteroidetes N OmpA family - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA DYD2_k127_6233963_7 1237149.C900_02611 1.101e-149 477.0 COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,47JX5@768503|Cytophagia 976|Bacteroidetes IQ Short-chain dehydrogenase reductase SDR ykuF - - ko:K13774 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short_C2 DYD2_k127_6233963_8 1237149.C900_02605 1.252e-141 482.0 COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,47MS3@768503|Cytophagia 976|Bacteroidetes S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - DUF3352 DYD2_k127_6251294_0 1237149.C900_03056 4.253e-154 491.0 COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia 976|Bacteroidetes C aconitate hydratase acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C DYD2_k127_6251294_1 1237149.C900_00316 2.565e-107 351.0 COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia 976|Bacteroidetes H TIGRFAM GTP cyclohydrolase I folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI DYD2_k127_6251294_2 1237149.C900_00318 1.836e-83 286.0 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia 976|Bacteroidetes M TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF DYD2_k127_6251294_3 1237149.C900_00319 1.134e-25 118.0 COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,4NU1P@976|Bacteroidetes,47XBG@768503|Cytophagia 976|Bacteroidetes Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS DYD2_k127_6251294_4 906888.JCM19314_1188 0.0008021 51.0 COG1345@1|root,COG3227@1|root,COG3291@1|root,COG3897@1|root,COG5384@1|root,COG1345@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,COG3897@2|Bacteria,COG5384@2|Bacteria,4NIGG@976|Bacteroidetes,1I0I5@117743|Flavobacteriia,3HKWF@363408|Nonlabens 976|Bacteroidetes EJN Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 DYD2_k127_6268850_1 1121904.ARBP01000016_gene5221 2.869e-136 446.0 COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,47M6X@768503|Cytophagia 976|Bacteroidetes Q PFAM Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 DYD2_k127_6268850_2 1101191.KI912577_gene2126 5.366e-123 406.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,1JTJD@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM FMN-dependent alpha-hydroxy acid dehydrogenase - - 1.1.2.3,1.1.3.46,1.13.12.4 ko:K00101,ko:K00467,ko:K16422 ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130 - R00196,R00319,R06633 RC00044,RC00240,RC01312 ko00000,ko00001,ko01000 - - - FMN_dh DYD2_k127_6268850_0 1123057.P872_03595 1.349e-213 671.0 COG0513@1|root,COG0513@2|Bacteria,4NE4Z@976|Bacteroidetes,47KF0@768503|Cytophagia 976|Bacteroidetes L DEAD DEAH box helicase dbpA - 3.6.4.13 ko:K05591 - - - - ko00000,ko01000,ko03009 - - - DEAD,DbpA,Helicase_C DYD2_k127_6268850_3 1237149.C900_05842 2.981e-47 172.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47NIF@768503|Cytophagia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_8 DYD2_k127_6268850_4 1237149.C900_05842 8.903e-45 168.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47NIF@768503|Cytophagia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_8 DYD2_k127_62804_3 1237149.C900_01765 3.022e-62 219.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,47JB7@768503|Cytophagia 976|Bacteroidetes E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase DYD2_k127_62804_0 246197.MXAN_6181 9.138e-180 572.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2YWED@29|Myxococcales 28221|Deltaproteobacteria U Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp DYD2_k127_62804_1 1237149.C900_04814 4.757e-124 410.0 COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 DYD2_k127_62804_2 1305737.JAFX01000001_gene736 1.666e-70 244.0 COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,47KKI@768503|Cytophagia 976|Bacteroidetes J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT DYD2_k127_629723_0 468059.AUHA01000003_gene1834 3.361e-142 471.0 COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia 976|Bacteroidetes T PFAM Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - Guanylate_cyc,Response_reg,TPR_12,TPR_8 DYD2_k127_629723_1 388413.ALPR1_02180 4.788e-57 208.0 COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,4NHSQ@976|Bacteroidetes,47KNM@768503|Cytophagia 976|Bacteroidetes O Subtilase family - - - - - - - - - - - - Peptidase_S8 DYD2_k127_6333540_11 391587.KAOT1_19592 5.216e-96 320.0 COG4242@1|root,COG4242@2|Bacteria,4NI55@976|Bacteroidetes,1HZY7@117743|Flavobacteriia 976|Bacteroidetes PQ Belongs to the peptidase S51 family cphB - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 DYD2_k127_6333540_0 391587.KAOT1_19597 0.0 1427.0 COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,4NEDY@976|Bacteroidetes,1HXFG@117743|Flavobacteriia 976|Bacteroidetes HJM cyanophycin synthetase cphA - 6.3.2.29,6.3.2.30 ko:K03802 - - - - ko00000,ko01000 - - - Mur_ligase_C,Mur_ligase_M,RimK DYD2_k127_6333540_15 1202532.FF52_10998 2.663e-48 200.0 COG1345@1|root,COG2911@1|root,COG3209@1|root,COG3386@1|root,COG4447@1|root,COG1345@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,COG4447@2|Bacteria,4NFVP@976|Bacteroidetes,1HY1K@117743|Flavobacteriia,2NSFX@237|Flavobacterium 976|Bacteroidetes N PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - PA14 DYD2_k127_6333540_16 1144313.PMI10_04031 1.965e-36 161.0 COG5492@1|root,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - Big_2,Big_5,CHU_C,Cadherin_3,Flg_new,LRR_5,Phage_tail_2,SLH DYD2_k127_6333540_18 926549.KI421517_gene28 2.27e-29 138.0 COG1520@1|root,COG2353@1|root,COG1520@2|Bacteria,COG2353@2|Bacteria,4PM20@976|Bacteroidetes,47X9N@768503|Cytophagia 976|Bacteroidetes S YceI-like domain - - - - - - - - - - - - - DYD2_k127_6333540_10 1237149.C900_04331 7.026e-103 338.0 COG1760@1|root,COG1760@2|Bacteria,4NFXU@976|Bacteroidetes,47NN2@768503|Cytophagia 976|Bacteroidetes E Serine dehydratase - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_beta DYD2_k127_6333540_7 1237149.C900_04332 2.36e-126 419.0 COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,47M95@768503|Cytophagia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP DYD2_k127_6333540_6 1237149.C900_04333 3.415e-158 511.0 COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,47JF4@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23,OEP DYD2_k127_6333540_8 1124780.ANNU01000075_gene835 7.754e-118 389.0 COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,47MBB@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 DYD2_k127_6333540_17 1236494.BAJN01000003_gene527 2.721e-36 145.0 COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia 976|Bacteroidetes D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf DYD2_k127_6333540_5 1237149.C900_04342 2.555e-213 668.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,47NI5@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 DYD2_k127_6333540_2 1185876.BN8_01562 4.666e-235 735.0 COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia 976|Bacteroidetes I PFAM Carbamoyl-phosphate synthase L chain, ATP binding - - 6.3.4.14,6.4.1.2,6.4.1.3 ko:K01961,ko:K01965 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00373,M00376,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD2_k127_6333540_4 1237149.C900_04344 8.313e-219 685.0 COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,47KDV@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II - - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_6333540_20 1270196.JCKI01000002_gene274 3.472e-21 93.0 2BVK8@1|root,32Y0S@2|Bacteria,4NUUA@976|Bacteroidetes,1ITXR@117747|Sphingobacteriia 976|Bacteroidetes S histone H1-like protein - - - - - - - - - - - - Hc1 DYD2_k127_6333540_9 1237149.C900_02553 6.665e-109 360.0 COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,47MC7@768503|Cytophagia 976|Bacteroidetes E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD2_k127_6333540_14 1237149.C900_02552 1.533e-48 179.0 2ENX1@1|root,33GHZ@2|Bacteria,4NXFU@976|Bacteroidetes,47WQI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6333540_1 643867.Ftrac_0818 8.648e-287 895.0 COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,47KR4@768503|Cytophagia 976|Bacteroidetes L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 DYD2_k127_6333540_12 1237149.C900_01578 1.029e-71 248.0 COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,47PRE@768503|Cytophagia 976|Bacteroidetes J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA DYD2_k127_6333540_19 1124780.ANNU01000002_gene1562 9.486e-27 111.0 COG4281@1|root,COG4281@2|Bacteria,4NVK0@976|Bacteroidetes,47RZ1@768503|Cytophagia 976|Bacteroidetes I Acyl CoA binding protein - - - - - - - - - - - - ACBP DYD2_k127_6333540_3 1237149.C900_01580 4.506e-226 705.0 COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia 976|Bacteroidetes C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD2_k127_6333540_13 1237149.C900_01581 2.326e-71 244.0 COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,47MT6@768503|Cytophagia 976|Bacteroidetes O PFAM SPFH domain Band 7 family - - - - - - - - - - - - Band_7 DYD2_k127_6333708_0 1121904.ARBP01000001_gene5338 0.0 1022.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,47M8E@768503|Cytophagia 976|Bacteroidetes J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 DYD2_k127_6333708_10 153721.MYP_3499 1.069e-59 211.0 COG0241@1|root,COG0241@2|Bacteria,4NNDD@976|Bacteroidetes,47QM8@768503|Cytophagia 976|Bacteroidetes E D,D-heptose 1,7-bisphosphate phosphatase gmhB - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - HAD_2,Hydrolase_like DYD2_k127_6333708_5 1408473.JHXO01000001_gene2529 3.035e-102 341.0 COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,2FM3A@200643|Bacteroidia 976|Bacteroidetes S Glycosyltransferase, group 2 family protein dpm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 DYD2_k127_6333708_12 1237149.C900_01120 1.345e-42 162.0 COG1595@1|root,COG1595@2|Bacteria,4NPMI@976|Bacteroidetes 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD2_k127_6333708_13 1484460.JSWG01000011_gene1751 2.957e-28 118.0 2ABS3@1|root,3118G@2|Bacteria,4NPFZ@976|Bacteroidetes,1I2IP@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6333708_1 1237149.C900_05673 5.446e-141 458.0 COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,47KVD@768503|Cytophagia 976|Bacteroidetes M ABC-type transport system involved in lipoprotein release permease component lolE_1 - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD DYD2_k127_6333708_2 1122621.ATZA01000036_gene3426 1.26e-139 454.0 COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1INZD@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Uncharacterised conserved protein UCP016719 - - - - - - - - - - - - DUF1343 DYD2_k127_6333708_11 313598.MED152_06365 1.69e-57 207.0 COG0652@1|root,COG0652@2|Bacteria,4NQYP@976|Bacteroidetes,1I3H5@117743|Flavobacteriia,3VV9C@52959|Polaribacter 976|Bacteroidetes G Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - - - - - - - - - - Pro_isomerase DYD2_k127_6333708_6 1121904.ARBP01000001_gene5464 7.958e-95 314.0 COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,47JCH@768503|Cytophagia 976|Bacteroidetes L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD DYD2_k127_6333708_3 1237149.C900_05676 1.007e-132 428.0 COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,47JDP@768503|Cytophagia 976|Bacteroidetes J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD2_k127_6333708_9 1237149.C900_02640 1.031e-61 216.0 COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,47Q9G@768503|Cytophagia 976|Bacteroidetes H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - 2TM,DHFR_1 DYD2_k127_6333708_15 1267535.KB906767_gene2973 7.444e-12 70.0 2EFWM@1|root,339NX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD2_k127_6333708_4 1237149.C900_02639 1.194e-103 343.0 COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,47Y2N@768503|Cytophagia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD2_k127_6333708_8 1250232.JQNJ01000001_gene3536 8.763e-71 247.0 COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,1HZ91@117743|Flavobacteriia 976|Bacteroidetes S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE DYD2_k127_6333708_7 1121904.ARBP01000012_gene1215 1.782e-94 321.0 28PR2@1|root,2ZCCZ@2|Bacteria,4NMVK@976|Bacteroidetes,47U8G@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6333708_14 714943.Mucpa_1259 1.103e-22 104.0 COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1IRV7@117747|Sphingobacteriia 976|Bacteroidetes Q membrane - - - - - - - - - - - - - DYD2_k127_6336502_4 1237149.C900_00391 1.099e-28 122.0 COG3595@1|root,COG3595@2|Bacteria,4NJBA@976|Bacteroidetes,47MRP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6336502_2 1237149.C900_00392 3.223e-58 211.0 COG5343@1|root,COG5343@2|Bacteria,4PNQ9@976|Bacteroidetes,47YF0@768503|Cytophagia 976|Bacteroidetes S HEAT repeats - - - - - - - - - - - - HEAT_2 DYD2_k127_6336502_1 1237149.C900_00393 1.446e-59 211.0 COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_6336502_5 1237149.C900_01259 3.869e-20 98.0 28P8J@1|root,2ZC2G@2|Bacteria,4NTQZ@976|Bacteroidetes,47SAC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6336502_3 926556.Echvi_1783 7.605e-41 155.0 COG2259@1|root,COG2259@2|Bacteria,4NP94@976|Bacteroidetes,47QI2@768503|Cytophagia 976|Bacteroidetes S DoxX - - - - - - - - - - - - DoxX DYD2_k127_6336502_0 1120999.JONM01000004_gene3524 2.182e-83 281.0 COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD2_k127_634212_0 1123248.KB893370_gene5155 8.257e-236 739.0 COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1IPV0@117747|Sphingobacteriia 976|Bacteroidetes S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase ramA_2 - - - - - - - - - - - Acetyltransf_1,CN_hydrolase DYD2_k127_634212_1 867902.Ornrh_1744 1.537e-164 529.0 COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,1HXXZ@117743|Flavobacteriia 976|Bacteroidetes P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 DYD2_k127_6442036_1 1122621.ATZA01000023_gene4229 9.621e-40 151.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4440 DYD2_k127_6442036_2 929556.Solca_1555 7.02e-22 99.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483,ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,HTH_Tnp_1,rve DYD2_k127_6442036_0 1317122.ATO12_19400 1.052e-97 327.0 COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,2YK2V@290174|Aquimarina 976|Bacteroidetes L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve DYD2_k127_6442036_3 1379270.AUXF01000007_gene1007 3.517e-12 69.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B DYD2_k127_6442742_2 1237149.C900_01034 3.885e-29 117.0 COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,47M4V@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop DYD2_k127_6442742_1 1237149.C900_01035 2.005e-56 204.0 COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia 976|Bacteroidetes L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N DYD2_k127_6442742_0 1237149.C900_04521 1.669e-76 263.0 COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,47PED@768503|Cytophagia 976|Bacteroidetes K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C DYD2_k127_6442742_3 1121129.KB903371_gene165 2.78e-23 100.0 COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,2FPG5@200643|Bacteroidia,22WQ1@171551|Porphyromonadaceae 976|Bacteroidetes T ATPase histidine kinase DNA gyrase B HSP90 domain protein rprX - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD2_k127_646538_0 1120966.AUBU01000002_gene2217 3.51e-226 725.0 COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,47KMB@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C DYD2_k127_646538_5 926549.KI421517_gene416 3.443e-45 167.0 COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 DYD2_k127_646538_2 1237149.C900_00952 7.034e-144 461.0 COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,47JDE@768503|Cytophagia 976|Bacteroidetes I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 DYD2_k127_646538_4 1121904.ARBP01000002_gene7203 1.106e-47 175.0 COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,47QG8@768503|Cytophagia 976|Bacteroidetes H TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK,dNK DYD2_k127_646538_1 1237149.C900_00949 1.273e-178 576.0 COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,47KQH@768503|Cytophagia 976|Bacteroidetes OU signal peptide peptidase SppA, 36K type sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 DYD2_k127_646538_3 1237149.C900_01672 2.132e-67 254.0 COG0457@1|root,COG4251@1|root,COG0457@2|Bacteria,COG4251@2|Bacteria,4P2V0@976|Bacteroidetes 976|Bacteroidetes T Tetratricopeptide repeat - - - - - - - - - - - - HATPase_c,TPR_12,TPR_8 DYD2_k127_6468561_17 1237149.C900_05622 3.393e-77 264.0 COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia 976|Bacteroidetes C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ DYD2_k127_6468561_2 1237149.C900_05621 1.791e-268 836.0 COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,47T90@768503|Cytophagia 976|Bacteroidetes F Formate--tetrahydrofolate ligase fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS DYD2_k127_6468561_25 380703.AHA_3669 6.037e-56 209.0 COG4123@1|root,COG4123@2|Bacteria,1PC8R@1224|Proteobacteria,1RM8S@1236|Gammaproteobacteria,1Y4BN@135624|Aeromonadales 135624|Aeromonadales J Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - 2.1.1.223 ko:K15460 - - - - ko00000,ko01000,ko03016 - - - MTS DYD2_k127_6468561_24 1237149.C900_05616 1.511e-60 214.0 COG2353@1|root,COG2353@2|Bacteria,4NPGK@976|Bacteroidetes 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI DYD2_k127_6468561_28 1237149.C900_05615 1.909e-43 164.0 COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47QE6@768503|Cytophagia 976|Bacteroidetes K transcriptional regulator slyA - - - - - - - - - - - MarR,MarR_2 DYD2_k127_6468561_3 1237149.C900_05611 2.296e-263 822.0 COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,47JSX@768503|Cytophagia 976|Bacteroidetes E PFAM peptidase M3A and M3B thimet oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N DYD2_k127_6468561_20 880071.Fleli_3570 1.919e-67 237.0 COG0730@1|root,COG0730@2|Bacteria,4NFTT@976|Bacteroidetes,47RU3@768503|Cytophagia 976|Bacteroidetes S PFAM Sulfite exporter TauE SafE - - - ko:K07090 - - - - ko00000 - - - TauE DYD2_k127_6468561_21 1121904.ARBP01000011_gene1451 1.029e-66 235.0 29R44@1|root,30C5C@2|Bacteria,4NN15@976|Bacteroidetes,47PN2@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6468561_33 153721.MYP_2205 5.364e-16 80.0 2ED1I@1|root,336YH@2|Bacteria,4NUYR@976|Bacteroidetes,47SW5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6468561_5 760192.Halhy_5254 6.383e-190 606.0 COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1IW8M@117747|Sphingobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471 DYD2_k127_6468561_23 1123278.KB893608_gene4566 9.276e-65 233.0 COG0793@1|root,COG0793@2|Bacteria,4NIQJ@976|Bacteroidetes,47QIN@768503|Cytophagia 976|Bacteroidetes M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 DYD2_k127_6468561_8 1237149.C900_05610 9.138e-175 554.0 COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,47KY6@768503|Cytophagia 976|Bacteroidetes C PFAM 2Fe-2S iron-sulfur cluster binding domain dmpP - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 DYD2_k127_6468561_4 926556.Echvi_0365 3.437e-205 650.0 COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,47KAQ@768503|Cytophagia 976|Bacteroidetes F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,ASL_C,Lyase_1 DYD2_k127_6468561_14 643867.Ftrac_3122 4.11e-110 361.0 COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,47K6K@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase domain rebM - - - - - - - - - - - Methyltransf_11 DYD2_k127_6468561_7 1124780.ANNU01000037_gene135 1.266e-178 562.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,47MD1@768503|Cytophagia 976|Bacteroidetes C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N DYD2_k127_6468561_13 452471.Aasi_1198 5.221e-112 376.0 COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia 976|Bacteroidetes D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS_C DYD2_k127_6468561_9 1237149.C900_04026 2.569e-174 561.0 COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,47KAE@768503|Cytophagia 976|Bacteroidetes M OstA-like protein - - - - - - - - - - - - OstA,OstA_2 DYD2_k127_6468561_26 1237149.C900_04025 2.15e-55 201.0 2AEI8@1|root,331SH@2|Bacteria,4NWWM@976|Bacteroidetes,47S6K@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6468561_16 1237149.C900_04024 3.089e-95 319.0 COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,47MWE@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Outer membrane assembly lipoprotein YfiO yfiO - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO DYD2_k127_6468561_29 1237149.C900_04023 4.414e-42 156.0 2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,47RC2@768503|Cytophagia 976|Bacteroidetes K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - - - - - - - - - - - RNA_pol_Rpb6 DYD2_k127_6468561_10 1237149.C900_04022 7.387e-174 553.0 COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,47MHR@768503|Cytophagia 976|Bacteroidetes H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein DYD2_k127_6468561_15 1237149.C900_04021 3.253e-108 357.0 28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,47N7V@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4835) - - - - - - - - - - - - DUF4835 DYD2_k127_6468561_6 1237149.C900_04019 2.316e-184 591.0 COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,47JTP@768503|Cytophagia 976|Bacteroidetes L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N DYD2_k127_6468561_32 1124780.ANNU01000062_gene565 2.211e-27 113.0 COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes,47X4S@768503|Cytophagia 976|Bacteroidetes S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ykfA - - - - - - - - - - - RRM_1 DYD2_k127_6468561_11 643867.Ftrac_2183 1.052e-145 476.0 COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,47JJT@768503|Cytophagia 976|Bacteroidetes P PFAM Sodium sulfate symporter transmembrane region - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp DYD2_k127_6468561_31 1237149.C900_04012 3.143e-30 124.0 2DQ9W@1|root,335IW@2|Bacteria,4NX9R@976|Bacteroidetes,47SCH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6468561_27 1237149.C900_04011 2.473e-49 182.0 COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,47QAU@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_6468561_30 1237149.C900_04030 3.361e-38 147.0 2DMMQ@1|root,32SHK@2|Bacteria,4NSZY@976|Bacteroidetes,47R9F@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF3052 DYD2_k127_6468561_22 1313301.AUGC01000001_gene1771 3.08e-65 228.0 2CC29@1|root,32RUM@2|Bacteria,4NS83@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - LPP20 DYD2_k127_6468561_19 1313301.AUGC01000001_gene1794 7.8e-69 251.0 2DMDZ@1|root,32QUA@2|Bacteria,4NSIY@976|Bacteroidetes 976|Bacteroidetes S LPP20 lipoprotein - - - - - - - - - - - - LPP20 DYD2_k127_6468561_12 1120966.AUBU01000002_gene2220 8.115e-137 437.0 COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia 976|Bacteroidetes C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein frdB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_7,Fer4_8 DYD2_k127_6468561_1 1237149.C900_04402 0.0 1098.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia 976|Bacteroidetes C TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD2_k127_6468561_18 1239962.C943_01477 6.571e-75 257.0 2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,47NEV@768503|Cytophagia 976|Bacteroidetes S TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - - DYD2_k127_6468561_0 643867.Ftrac_3357 0.0 1707.0 COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon DYD2_k127_6489005_10 1349785.BAUG01000035_gene1961 1.605e-49 185.0 2B2RR@1|root,2Z9ZD@2|Bacteria,4NKN4@976|Bacteroidetes,1II67@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6489005_8 926549.KI421517_gene3694 2.92e-61 217.0 COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,47PF2@768503|Cytophagia 976|Bacteroidetes S protein conserved in bacteria - - - ko:K09931 - - - - ko00000 - - - DUF2064 DYD2_k127_6489005_11 1237149.C900_04736 4.372e-44 165.0 COG0607@1|root,COG0607@2|Bacteria,4NQ61@976|Bacteroidetes,47Q3A@768503|Cytophagia 976|Bacteroidetes P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese DYD2_k127_6489005_4 1237149.C900_04735 3.443e-106 360.0 COG0463@1|root,COG0463@2|Bacteria,4PM7X@976|Bacteroidetes,47Y12@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase, family 2 - - - - - - - - - - - - GT87 DYD2_k127_6489005_1 1237149.C900_04734 5.552e-209 659.0 COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,47MJK@768503|Cytophagia 976|Bacteroidetes M glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD2_k127_6489005_5 1237149.C900_04733 1.101e-102 338.0 COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,47M1F@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD2_k127_6489005_0 761193.Runsl_1616 3.735e-209 662.0 COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain yccM_2 - - - - - - - - - - - Fer4,Fer4_5,Fer4_7,Fer4_9 DYD2_k127_6489005_2 1237149.C900_02900 3.2e-192 608.0 COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,47JW2@768503|Cytophagia 976|Bacteroidetes S Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 DYD2_k127_6489005_6 1237149.C900_03812 2.124e-69 242.0 COG0398@1|root,COG0398@2|Bacteria,4NHA2@976|Bacteroidetes,47S54@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 DYD2_k127_6489005_12 1434325.AZQN01000004_gene1690 5.474e-31 126.0 COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes 976|Bacteroidetes C cytochrome C nirK - 1.7.2.1 ko:K00368,ko:K00405 ko00190,ko00910,ko01100,ko01120,ko02020,map00190,map00910,map01100,map01120,map02020 M00156,M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cu-oxidase,Cu-oxidase_3,Cytochrom_C,Cytochrome_CBB3 DYD2_k127_6489005_9 509635.N824_05185 1.007e-60 218.0 2DBAY@1|root,2Z84S@2|Bacteria,4NGXD@976|Bacteroidetes,1IWW9@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF1835 DYD2_k127_6489005_7 1185876.BN8_02316 2.58e-66 229.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47PGG@768503|Cytophagia 976|Bacteroidetes C Aerobic-type carbon monoxide dehydrogenase small subunit CoxS - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 DYD2_k127_6489005_3 1237149.C900_00537 5.282e-123 405.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD2_k127_6493245_7 1279009.ADICEAN_01481 7.806e-39 152.0 28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,47SGM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6493245_5 1230343.CANP01000042_gene3124 9.987e-116 383.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RYK4@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD2_k127_6493245_4 1237149.C900_01002 2.505e-116 378.0 COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,47KUT@768503|Cytophagia 976|Bacteroidetes KT Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg DYD2_k127_6493245_3 1237149.C900_01001 4.195e-119 394.0 COG2972@1|root,COG2972@2|Bacteria,4NIER@976|Bacteroidetes,47P26@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,His_kinase DYD2_k127_6493245_2 1237149.C900_01000 5.521e-127 418.0 COG0308@1|root,COG0308@2|Bacteria,4PNPR@976|Bacteroidetes,47YF9@768503|Cytophagia 976|Bacteroidetes E CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 DYD2_k127_6493245_6 313606.M23134_04812 2.236e-57 212.0 28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - BetR DYD2_k127_6493245_1 1237149.C900_00996 3.735e-134 436.0 COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,47K45@768503|Cytophagia 976|Bacteroidetes M pfkB family carbohydrate kinase rfaE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB DYD2_k127_6493245_0 1237149.C900_00995 1.426e-189 599.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,47JJH@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_6493245_9 68223.JNZY01000003_gene4734 6.492e-12 77.0 COG0662@1|root,COG0662@2|Bacteria,2IHNU@201174|Actinobacteria 201174|Actinobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD2_k127_6495318_8 1237149.C900_02767 1.788e-114 372.0 COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,47JAQ@768503|Cytophagia 976|Bacteroidetes C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 DYD2_k127_6495318_20 1185876.BN8_06325 1.978e-16 81.0 2A7GX@1|root,30WEH@2|Bacteria,4P9UT@976|Bacteroidetes,47S3Y@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6495318_1 1237149.C900_02768 1.793e-203 644.0 COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,47JE1@768503|Cytophagia 976|Bacteroidetes S Oxygen tolerance - - - - - - - - - - - - BatD DYD2_k127_6495318_5 1123057.P872_02220 1.557e-173 549.0 COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,47KB2@768503|Cytophagia 976|Bacteroidetes E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt DYD2_k127_6495318_18 1237149.C900_00291 7.993e-55 195.0 2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD2_k127_6495318_7 518766.Rmar_0956 9.151e-140 456.0 COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1FIV5@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - - - - - - - - - - SDF DYD2_k127_6495318_2 468059.AUHA01000003_gene1460 4.416e-188 598.0 COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1INWV@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - ko:K11102 - - - - ko00000,ko02000 2.A.23.1.1,2.A.23.1.2 - - SDF DYD2_k127_6495318_16 1237149.C900_02771 1.591e-75 257.0 COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,47PV2@768503|Cytophagia 976|Bacteroidetes O PFAM Scaffold protein Nfu NifU N terminal - - - - - - - - - - - - Nfu_N,NifU DYD2_k127_6495318_19 929713.NIASO_02860 4.147e-47 173.0 COG3832@1|root,COG3832@2|Bacteria,4NNTR@976|Bacteroidetes,1IQR8@117747|Sphingobacteriia 976|Bacteroidetes S Pfam Activator of Hsp90 ATPase - - - - - - - - - - - - AHSA1 DYD2_k127_6495318_11 1237149.C900_02777 1.333e-93 316.0 COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia 976|Bacteroidetes EG PFAM EamA-like transporter family fjo11 - - - - - - - - - - - EamA DYD2_k127_6495318_4 1089547.KB913013_gene213 2.934e-174 550.0 COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,47JGV@768503|Cytophagia 976|Bacteroidetes J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus DYD2_k127_6495318_14 1237149.C900_02779 1.78e-83 287.0 COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,47JZ8@768503|Cytophagia 976|Bacteroidetes S PFAM CAAX amino terminal protease family - - - ko:K07052 - - - - ko00000 - - - Abi DYD2_k127_6495318_9 643867.Ftrac_2763 9.052e-114 372.0 COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,47KPM@768503|Cytophagia 976|Bacteroidetes S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 DYD2_k127_6495318_0 1237149.C900_02782 3.429e-242 751.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47K4Z@768503|Cytophagia 976|Bacteroidetes E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD2_k127_6495318_13 1189612.A33Q_2291 9.941e-88 294.0 COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,47MWN@768503|Cytophagia 976|Bacteroidetes I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase DYD2_k127_6495318_6 1239962.C943_04256 3.464e-156 501.0 COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia 976|Bacteroidetes I fatty acid desaturase - - 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase DYD2_k127_6495318_12 760192.Halhy_5011 8.125e-88 303.0 COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1IRI9@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Aminotransferase class I and II - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD2_k127_6495318_10 743722.Sph21_4406 8.693e-113 385.0 COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,1IQ4B@117747|Sphingobacteriia 976|Bacteroidetes L SMART DNA mismatch repair protein MutS mutS_2 - - - - - - - - - - - MutS_III,MutS_V DYD2_k127_6495318_17 1124780.ANNU01000005_gene2447 9.754e-71 242.0 COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,47PCM@768503|Cytophagia 976|Bacteroidetes T GAF domain-containing protein msrC - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF,GAF_2 DYD2_k127_6495318_15 1237149.C900_03145 1.268e-80 274.0 COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia 976|Bacteroidetes M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 DYD2_k127_6495318_3 1124780.ANNU01000006_gene2891 2.436e-183 586.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,47JWU@768503|Cytophagia 976|Bacteroidetes J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 DYD2_k127_6495410_4 1237149.C900_02766 1.079e-183 578.0 COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,47M82@768503|Cytophagia 976|Bacteroidetes L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N DYD2_k127_6495410_5 1237149.C900_02765 5.792e-119 392.0 COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,47N34@768503|Cytophagia 976|Bacteroidetes H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE DYD2_k127_6495410_9 1237149.C900_02763 6.391e-82 279.0 COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,47Q1F@768503|Cytophagia 976|Bacteroidetes P ZIP Zinc transporter - - - - - - - - - - - - Zip DYD2_k127_6495410_7 1237149.C900_03820 4.973e-88 301.0 COG0859@1|root,COG0859@2|Bacteria,4P2TG@976|Bacteroidetes 976|Bacteroidetes M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 DYD2_k127_6495410_11 1237149.C900_03821 2.292e-72 257.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 DYD2_k127_6495410_18 688269.Theth_0887 3.035e-14 84.0 COG0438@1|root,COG0438@2|Bacteria,2GCQU@200918|Thermotogae 200918|Thermotogae M PFAM glycosyl transferase group 1 - - 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 DYD2_k127_6495410_8 1237149.C900_03822 5.111e-85 293.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD2_k127_6495410_15 385682.AFSL01000049_gene505 4.885e-60 229.0 COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,2FMUK@200643|Bacteroidia,3XJSM@558415|Marinilabiliaceae 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD2_k127_6495410_3 1237149.C900_03019 8.51e-189 599.0 COG1032@1|root,COG1032@2|Bacteria,4NKFV@976|Bacteroidetes 976|Bacteroidetes C Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM DYD2_k127_6495410_13 1237149.C900_03020 1.244e-66 235.0 COG0500@1|root,COG2226@2|Bacteria,4NICK@976|Bacteroidetes 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 DYD2_k127_6495410_2 1237149.C900_03021 5.262e-201 636.0 COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes 976|Bacteroidetes C Fe-S oxidoreductase - - - - - - - - - - - - B12-binding,Radical_SAM DYD2_k127_6495410_10 1237149.C900_03022 1.026e-79 278.0 COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes 976|Bacteroidetes S nucleotidyltransferase activity - - - - - - - - - - - - NTP_transf_2 DYD2_k127_6495410_16 1237149.C900_03023 1.813e-53 205.0 COG3307@1|root,COG3307@2|Bacteria,4NUP9@976|Bacteroidetes,47V2J@768503|Cytophagia 976|Bacteroidetes M O-antigen ligase like membrane protein - - - - - - - - - - - - Wzy_C DYD2_k127_6495410_6 1237149.C900_03024 7.724e-107 353.0 COG1216@1|root,COG1216@2|Bacteria,4NGNS@976|Bacteroidetes,47UUA@768503|Cytophagia 976|Bacteroidetes S Glycosyltransferase like family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glycos_transf_2 DYD2_k127_6495410_14 1235788.C802_03705 2.229e-65 231.0 COG1215@1|root,COG1215@2|Bacteria,4NNFI@976|Bacteroidetes,2FSV3@200643|Bacteroidia,4ARAE@815|Bacteroidaceae 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 DYD2_k127_6495410_12 35841.BT1A1_3280 1.913e-69 250.0 2BIRY@1|root,32CZI@2|Bacteria,1UBSI@1239|Firmicutes,4IN7Q@91061|Bacilli,1ZMZP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - DYD2_k127_6495410_17 316067.Geob_1464 3.853e-29 127.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 DYD2_k127_6495410_0 1286632.P278_08660 3.876e-297 922.0 COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1HYA0@117743|Flavobacteriia 976|Bacteroidetes I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD2_k127_6495410_1 1237149.C900_02809 1.694e-275 852.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47JEH@768503|Cytophagia 976|Bacteroidetes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN DYD2_k127_6636300_2 1234664.AMRO01000079_gene559 8.274e-131 426.0 COG0028@1|root,COG4032@1|root,COG0028@2|Bacteria,COG4032@2|Bacteria,1TSJZ@1239|Firmicutes,4HDPN@91061|Bacilli,1WH60@129337|Geobacillus 91061|Bacilli EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - 4.1.1.82 ko:K09459 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R04053 RC00506 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_N DYD2_k127_6636300_0 1295642.H839_06464 9.162e-246 768.0 COG1213@1|root,COG2513@1|root,COG1213@2|Bacteria,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,4HCDV@91061|Bacilli,1WH75@129337|Geobacillus 91061|Bacilli GM Phosphoenolpyruvate phosphomutase - - 5.4.2.9 ko:K01841 ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130 - R00661 RC02792 ko00000,ko00001,ko01000 - - - NTP_transf_3,PEP_mutase DYD2_k127_6636300_4 754027.HMPREF9554_00612 2.123e-36 150.0 COG5050@1|root,COG5050@2|Bacteria,2J6FJ@203691|Spirochaetes 203691|Spirochaetes I Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - - - - - - - - - - CDP-OH_P_transf DYD2_k127_6636300_3 880072.Desac_2271 2.033e-115 382.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WK6J@28221|Deltaproteobacteria,2MRKP@213462|Syntrophobacterales 28221|Deltaproteobacteria H Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K03430 ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R04152 RC00006,RC00008,RC00018,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD2_k127_6636300_5 391598.FBBAL38_12760 1.505e-23 105.0 COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,1I51Q@117743|Flavobacteriia 976|Bacteroidetes P rhodanese-related sulfurtransferase - - - - - - - - - - - - Rhodanese,Thioredoxin DYD2_k127_6636300_1 1237149.C900_05255 4.092e-204 656.0 COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia 976|Bacteroidetes N C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD,SBBP DYD2_k127_665294_16 313606.M23134_03259 2.201e-47 174.0 COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes,47PU3@768503|Cytophagia 976|Bacteroidetes P Belongs to the Fur family zur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR DYD2_k127_665294_6 1237149.C900_04621 2.06e-138 446.0 COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,47N45@768503|Cytophagia 976|Bacteroidetes P PFAM Integral membrane protein TerC ygjT - - ko:K05794 - - - - ko00000 - - - TerC DYD2_k127_665294_12 1237149.C900_04619 3.054e-72 246.0 COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,47PQS@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC DYD2_k127_665294_4 1124780.ANNU01000048_gene2149 2.487e-162 518.0 COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia 976|Bacteroidetes F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp DYD2_k127_665294_2 1237149.C900_03447 9.933e-268 841.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate DYD2_k127_665294_20 1237149.C900_03448 7.21e-17 82.0 COG1918@1|root,COG1918@2|Bacteria,4NUWI@976|Bacteroidetes,47RUN@768503|Cytophagia 976|Bacteroidetes P FeoA feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA DYD2_k127_665294_1 1237149.C900_00798 2.189e-280 883.0 COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,47JKP@768503|Cytophagia 976|Bacteroidetes M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,6.3.2.10 ko:K01775,ko:K01929 ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502 - R00401,R04573,R04617 RC00064,RC00141,RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M DYD2_k127_665294_17 1128421.JAGA01000003_gene3410 2.038e-45 166.0 COG0073@1|root,COG0073@2|Bacteria,2NPKM@2323|unclassified Bacteria 2|Bacteria J Putative tRNA binding domain csaA GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20,6.1.1.6 ko:K01874,ko:K01890,ko:K04566,ko:K06878 ko00450,ko00970,map00450,map00970 M00359,M00360 R03658,R03659,R03660,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA_bind DYD2_k127_665294_3 1237149.C900_02057 1.048e-174 553.0 COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,47MPT@768503|Cytophagia 976|Bacteroidetes J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD2_k127_665294_13 1237149.C900_02113 2.43e-67 239.0 COG0823@1|root,COG0823@2|Bacteria,4PME8@976|Bacteroidetes,47Y2Q@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - DYD2_k127_665294_18 1237149.C900_05847 3.095e-35 141.0 2ESEN@1|root,33JZB@2|Bacteria,4NZ9T@976|Bacteroidetes,47VE9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_665294_9 643867.Ftrac_1505 1.367e-111 368.0 COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,47JRS@768503|Cytophagia 976|Bacteroidetes H Belongs to the FPP GGPP synthase family idsA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt DYD2_k127_665294_0 1237149.C900_02107 5.692e-307 955.0 COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,47JK7@768503|Cytophagia 976|Bacteroidetes J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573,ko:K12585 ko03018,map03018 M00391 - - ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 DYD2_k127_665294_11 1237149.C900_02108 9.665e-81 275.0 COG3298@1|root,COG3298@2|Bacteria,4NECH@976|Bacteroidetes,47Y3D@768503|Cytophagia 976|Bacteroidetes L Predicted 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 DYD2_k127_665294_10 700598.Niako_4375 3.753e-106 352.0 COG0583@1|root,COG0583@2|Bacteria,4NHTU@976|Bacteroidetes,1IWM3@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate DYD2_k127_665294_5 700598.Niako_4376 1.062e-148 480.0 COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1ITTX@117747|Sphingobacteriia 976|Bacteroidetes E Pyridoxal-phosphate dependent enzyme - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_665294_15 1237149.C900_02109 4.543e-48 175.0 2AGNU@1|root,316WB@2|Bacteria,4NSNZ@976|Bacteroidetes,47RK1@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_665294_7 1120965.AUBV01000001_gene3457 1.227e-119 393.0 COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia 976|Bacteroidetes S RelA SpoT domain protein - - - - - - - - - - - - GTA_TIM DYD2_k127_665294_14 1237149.C900_02110 1.531e-56 199.0 COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia 976|Bacteroidetes H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB DYD2_k127_6655214_3 1004149.AFOE01000017_gene798 3.31e-100 335.0 COG2610@1|root,COG2610@2|Bacteria,4NFBD@976|Bacteroidetes,1HY9I@117743|Flavobacteriia 976|Bacteroidetes EG H gluconate symporter and related - - - ko:K03299,ko:K06156 - - - - ko00000,ko02000 2.A.8,2.A.8.1.8 - - GntP_permease DYD2_k127_6655214_6 1121875.KB907547_gene3151 5.839e-16 82.0 2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes,1I9XX@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_6655214_2 313603.FB2170_07914 3.338e-163 526.0 COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1HYY8@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M DYD2_k127_6655214_1 742725.HMPREF9450_00518 1.528e-202 643.0 COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,2FNXD@200643|Bacteroidia 976|Bacteroidetes C proton-translocating NADH-quinone oxidoreductase, chain M nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M DYD2_k127_6655214_0 1211813.CAPH01000009_gene81 1.408e-249 784.0 COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,2FPCT@200643|Bacteroidia,22U55@171550|Rikenellaceae 976|Bacteroidetes CP Proton-translocating NADH-quinone oxidoreductase, chain L nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N DYD2_k127_6655214_5 1408473.JHXO01000002_gene3882 5.072e-34 133.0 COG0713@1|root,COG0713@2|Bacteria,4NR5Y@976|Bacteroidetes,2G3CR@200643|Bacteroidia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD2_k127_6655214_4 313603.FB2170_07934 7.906e-40 154.0 COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I26W@117743|Flavobacteriia 976|Bacteroidetes C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD2_k127_67098_18 1237149.C900_02726 1.849e-78 265.0 COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,47KI4@768503|Cytophagia 976|Bacteroidetes G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase DYD2_k127_67098_7 1237149.C900_02725 2.744e-111 370.0 COG2067@1|root,COG2067@2|Bacteria,4PKQK@976|Bacteroidetes,47XZ1@768503|Cytophagia 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - - DYD2_k127_67098_17 1237149.C900_02724 6.118e-80 273.0 COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,47PKF@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl DYD2_k127_67098_8 1185876.BN8_05443 5.157e-110 360.0 COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,47MC0@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD2_k127_67098_0 1237149.C900_02722 0.0 1102.0 COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,47JEC@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein assembly complex, YaeT protein yaeT - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA DYD2_k127_67098_20 1237149.C900_02721 2.368e-66 231.0 COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,47PD1@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane protein (OmpH-like) skp - - ko:K06142 - - - - ko00000 - - - OmpH DYD2_k127_67098_25 1237149.C900_02720 3.927e-57 205.0 COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes,47QWE@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH DYD2_k127_67098_15 1237149.C900_02719 2.959e-92 312.0 COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,47KS4@768503|Cytophagia 976|Bacteroidetes V peptidase U61 LD-carboxypeptidase A ykfA - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 DYD2_k127_67098_2 1237149.C900_00792 4.08e-144 465.0 COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,47M9W@768503|Cytophagia 976|Bacteroidetes J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD2_k127_67098_34 1453500.AT05_08105 8.975e-23 104.0 2CC29@1|root,32RUM@2|Bacteria,4NS83@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_67098_16 1237149.C900_01543 1.904e-85 288.0 COG0500@1|root,COG2226@2|Bacteria,4NM9E@976|Bacteroidetes,47PMX@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase - - - - - - - - - - - - Methyltransf_25,Methyltransf_31 DYD2_k127_67098_4 1124780.ANNU01000006_gene2848 2.151e-124 408.0 COG3424@1|root,COG3424@2|Bacteria,4NDZU@976|Bacteroidetes,47JU1@768503|Cytophagia 976|Bacteroidetes Q PFAM chalcone and stilbene bcsA - - - - - - - - - - - Chal_sti_synt_C,Chal_sti_synt_N DYD2_k127_67098_10 1237149.C900_01545 1.378e-105 350.0 COG0382@1|root,COG0382@2|Bacteria,4NK26@976|Bacteroidetes,47N2W@768503|Cytophagia 976|Bacteroidetes H UbiA prenyltransferase family - - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD2_k127_67098_3 1237149.C900_03489 1.319e-128 420.0 COG0644@1|root,COG0644@2|Bacteria,4NE67@976|Bacteroidetes,47M1U@768503|Cytophagia 976|Bacteroidetes C FAD binding domain fixC - - - - - - - - - - - FAD_binding_3,Lycopene_cycl,SE,Trp_halogenase DYD2_k127_67098_33 1237149.C900_03491 4.595e-29 121.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - DUF2087,GerE,Mor,Response_reg,Y_Y_Y DYD2_k127_67098_13 1237149.C900_03492 7.572e-96 328.0 COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia 976|Bacteroidetes M PDZ DHR GLGF domain protein - - - - - - - - - - - - Asp_protease_2,PDZ,PDZ_2 DYD2_k127_67098_24 1237149.C900_03494 1.963e-58 208.0 COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,47Q15@768503|Cytophagia 976|Bacteroidetes S Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD2_k127_67098_23 1237149.C900_03497 4.968e-61 215.0 COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 DYD2_k127_67098_5 1237149.C900_03498 3.751e-119 403.0 COG2885@1|root,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes,47K81@768503|Cytophagia 976|Bacteroidetes MU OmpA family - - - - - - - - - - - - PD40 DYD2_k127_67098_11 1237149.C900_00804 7.74e-104 342.0 COG0106@1|root,COG0106@2|Bacteria,4NK0E@976|Bacteroidetes,47NT9@768503|Cytophagia 976|Bacteroidetes E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase - - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD2_k127_67098_32 153721.MYP_276 6.734e-32 129.0 COG0784@1|root,COG0784@2|Bacteria,4PKNR@976|Bacteroidetes,47XXN@768503|Cytophagia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD2_k127_67098_12 1121904.ARBP01000001_gene5991 1.083e-103 357.0 COG2355@1|root,COG2355@2|Bacteria,4NP5X@976|Bacteroidetes,47PUH@768503|Cytophagia 976|Bacteroidetes E Zn-dependent dipeptidase, microsomal dipeptidase - - - - - - - - - - - - - DYD2_k127_67098_36 118166.JH976537_gene1619 0.0003573 48.0 COG0745@1|root,COG0745@2|Bacteria,1FZXT@1117|Cyanobacteria,1H926@1150|Oscillatoriales 1117|Cyanobacteria T PFAM Response regulator receiver domain - - - - - - - - - - - - Response_reg,Trans_reg_C DYD2_k127_67098_21 1237149.C900_05519 4.645e-66 231.0 COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia 976|Bacteroidetes T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg DYD2_k127_67098_30 1237149.C900_05518 1.307e-41 162.0 COG4585@1|root,COG4585@2|Bacteria,4NN4R@976|Bacteroidetes,47N81@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 DYD2_k127_67098_22 1123057.P872_24300 6.983e-65 226.0 COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,47QAB@768503|Cytophagia 976|Bacteroidetes J translation initiation inhibitor, yjgF family - - - - - - - - - - - - YjgF_endoribonc DYD2_k127_67098_14 643867.Ftrac_2148 6.742e-93 307.0 COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,47PXB@768503|Cytophagia 976|Bacteroidetes L PFAM methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco DYD2_k127_67098_26 1237149.C900_04499 6.631e-57 204.0 COG1280@1|root,COG1280@2|Bacteria,4NUV7@976|Bacteroidetes,47SDU@768503|Cytophagia 976|Bacteroidetes E LysE type translocator - - - - - - - - - - - - LysE DYD2_k127_67098_9 1185876.BN8_01979 9.439e-106 353.0 COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes,47MCV@768503|Cytophagia 976|Bacteroidetes HJ ligase activity - - - - - - - - - - - - RimK DYD2_k127_67098_28 1237149.C900_04497 1.366e-49 182.0 COG2318@1|root,COG2318@2|Bacteria,4NSP0@976|Bacteroidetes,47R5Z@768503|Cytophagia 976|Bacteroidetes S DinB family - - - - - - - - - - - - DinB,DinB_2 DYD2_k127_67098_27 1237149.C900_04496 1.618e-50 183.0 COG3350@1|root,COG3350@2|Bacteria,4NRFU@976|Bacteroidetes,47QIJ@768503|Cytophagia 976|Bacteroidetes S monooxygenase activity - - - - - - - - - - - - YHS DYD2_k127_67098_29 269798.CHU_3722 1.979e-44 166.0 COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,47QBK@768503|Cytophagia 976|Bacteroidetes S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX DYD2_k127_67098_19 1237149.C900_04494 2.131e-71 244.0 2C88U@1|root,2ZAHP@2|Bacteria,4NK63@976|Bacteroidetes,47NBI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - YcxB DYD2_k127_67098_6 1237149.C900_04493 4.481e-117 383.0 COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,47JJ8@768503|Cytophagia 976|Bacteroidetes H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N DYD2_k127_67098_31 1237149.C900_04492 3.899e-40 152.0 2E4SF@1|root,32ZKW@2|Bacteria,4NV4G@976|Bacteroidetes,47RXS@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4783) - - - - - - - - - - - - DUF4783 DYD2_k127_67098_1 1237149.C900_04626 2.894e-246 768.0 COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,47K1F@768503|Cytophagia 976|Bacteroidetes G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N DYD2_k127_6730935_2 1379698.RBG1_1C00001G1428 1.322e-06 53.0 COG2911@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NS5I@2323|unclassified Bacteria 2|Bacteria U FlgD Ig-like domain - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Cytochrome_C554,DUF11,FlgD_ig,PKD,SLH DYD2_k127_6730935_0 643867.Ftrac_1104 8.8e-110 367.0 COG4249@1|root,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes,47UFX@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,TPR_16 DYD2_k127_6730935_1 1237149.C900_01522 7.637e-79 278.0 COG3292@1|root,COG3292@2|Bacteria,4NNTX@976|Bacteroidetes,47U09@768503|Cytophagia 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - Y_Y_Y DYD2_k127_685089_0 1237149.C900_02826 0.0 1230.0 COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,47JXI@768503|Cytophagia 976|Bacteroidetes C 2-oxoglutarate dehydrogenase, E1 sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr DYD2_k127_685089_2 1124780.ANNU01000052_gene3584 9.179e-199 631.0 COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,47K2Z@768503|Cytophagia 976|Bacteroidetes C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD2_k127_685089_1 1237149.C900_02822 3.446e-250 777.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47K0E@768503|Cytophagia 976|Bacteroidetes C Dihydrolipoyl dehydrogenase lpd - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim DYD2_k127_685089_4 1237149.C900_01804 3.64e-125 413.0 28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,47M50@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 DYD2_k127_685089_3 1237149.C900_01806 2.288e-171 542.0 COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia 976|Bacteroidetes C Radical SAM - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM DYD2_k127_685089_5 1237149.C900_01733 2.663e-93 314.0 COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia 976|Bacteroidetes G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P DYD2_k127_685089_6 1237149.C900_01732 1.468e-08 60.0 COG0815@1|root,COG0815@2|Bacteria 2|Bacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase DYD2_k127_792536_2 761193.Runsl_4298 7.114e-47 172.0 COG3631@1|root,COG3631@2|Bacteria,4NQGX@976|Bacteroidetes,47R4P@768503|Cytophagia 976|Bacteroidetes S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 DYD2_k127_792536_0 313606.M23134_05124 9.947e-127 411.0 COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,47JFF@768503|Cytophagia 976|Bacteroidetes S Carbon-nitrogen hydrolase - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase DYD2_k127_792536_1 643867.Ftrac_2941 1.783e-61 220.0 COG3595@1|root,COG3595@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2807 DYD2_k127_820312_2 1121904.ARBP01000001_gene5377 5.752e-194 614.0 COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia 976|Bacteroidetes S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 DYD2_k127_820312_3 1283300.ATXB01000001_gene2143 7.009e-170 551.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_7 DYD2_k127_820312_0 1237149.C900_01776 0.0 1463.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,47K29@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P DYD2_k127_820312_8 1189612.A33Q_2687 8.706e-66 227.0 COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,47PQ3@768503|Cytophagia 976|Bacteroidetes F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK DYD2_k127_820312_4 1237149.C900_03206 1.561e-126 414.0 COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,47JVC@768503|Cytophagia 976|Bacteroidetes S phosphoesterase RecJ domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD2_k127_820312_7 1237149.C900_03205 2.269e-67 241.0 COG0545@1|root,COG0545@2|Bacteria,4NPBZ@976|Bacteroidetes,47XJV@768503|Cytophagia 976|Bacteroidetes M FKBP-type peptidyl-prolyl cis-trans isomerase - - - - - - - - - - - - FKBP_C DYD2_k127_820312_9 1121930.AQXG01000009_gene270 2.747e-31 128.0 COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes 976|Bacteroidetes O Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C DYD2_k127_820312_5 926549.KI421517_gene165 2.806e-72 248.0 COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,47PE9@768503|Cytophagia 976|Bacteroidetes F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like DYD2_k127_820312_6 880070.Cycma_1509 3.726e-72 249.0 COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,47P8Z@768503|Cytophagia 976|Bacteroidetes F Belongs to the uridine kinase family udk - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK DYD2_k127_820312_1 643867.Ftrac_1996 3.891e-254 803.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,47JV4@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG DYD2_k127_831004_6 1237149.C900_04708 3.478e-07 55.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,47KJK@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD2_k127_831004_0 1124780.ANNU01000028_gene999 2.513e-198 628.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47JDQ@768503|Cytophagia 976|Bacteroidetes J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD2_k127_831004_5 1237149.C900_04710 2.297e-17 83.0 COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,47S09@768503|Cytophagia 976|Bacteroidetes U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD2_k127_831004_2 1237149.C900_04711 6.21e-128 420.0 COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,47JWJ@768503|Cytophagia 976|Bacteroidetes D Peptidase, M23 envC - - - - - - - - - - - Peptidase_M23 DYD2_k127_831004_4 1124780.ANNU01000028_gene996 9.195e-46 174.0 COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,47N94@768503|Cytophagia 976|Bacteroidetes M Domain of unknown function (DUF4292) - - - - - - - - - - - - DUF4292 DYD2_k127_831004_1 1237149.C900_04713 5.53e-145 479.0 COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,47KE1@768503|Cytophagia 976|Bacteroidetes S PFAM Tetratricopeptide - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 DYD2_k127_831004_3 926549.KI421517_gene1850 1.929e-78 271.0 COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,47MQE@768503|Cytophagia 976|Bacteroidetes S Polysaccharide biosynthesis protein cap - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C DYD2_k127_851253_7 714943.Mucpa_5555 2.042e-11 64.0 COG5504@1|root,COG5504@2|Bacteria,4NJ10@976|Bacteroidetes,1IR6N@117747|Sphingobacteriia 976|Bacteroidetes O Predicted Zn-dependent protease (DUF2268) - - - - - - - - - - - - CBM_20,DUF2268 DYD2_k127_851253_1 1392498.JQLH01000001_gene230 9.659e-152 490.0 COG4941@1|root,COG4941@2|Bacteria,4NGCS@976|Bacteroidetes,1I06D@117743|Flavobacteriia,2PHXN@252356|Maribacter 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_851253_5 1249997.JHZW01000002_gene1001 2.145e-44 163.0 COG3795@1|root,COG3795@2|Bacteria,4NQPY@976|Bacteroidetes,1I3KU@117743|Flavobacteriia,2PIMT@252356|Maribacter 976|Bacteroidetes S YCII-related domain - - - - - - - - - - - - YCII DYD2_k127_851253_6 1317122.ATO12_05715 1.977e-39 149.0 COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,1I3SY@117743|Flavobacteriia,2YJI3@290174|Aquimarina 976|Bacteroidetes S Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase DYD2_k127_851253_9 1121875.KB907548_gene1523 7.086e-07 58.0 2C8EV@1|root,32RM1@2|Bacteria,4NU8V@976|Bacteroidetes,1I47A@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_851253_4 1237149.C900_04569 4.284e-47 171.0 COG3874@1|root,COG3874@2|Bacteria,4NTIV@976|Bacteroidetes,47VMT@768503|Cytophagia 976|Bacteroidetes S Sporulation protein YtfJ (Spore_YtfJ) - - - - - - - - - - - - Spore_YtfJ DYD2_k127_851253_3 388413.ALPR1_05690 6.964e-108 354.0 COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes,47P5T@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase molybdopterin binding domain - - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb DYD2_k127_851253_2 388413.ALPR1_05685 1.367e-108 357.0 COG4117@1|root,COG4117@2|Bacteria,4NG6M@976|Bacteroidetes,47NBT@768503|Cytophagia 976|Bacteroidetes C Prokaryotic cytochrome b561 - - - - - - - - - - - - Ni_hydr_CYTB,Oxidored_molyb DYD2_k127_851253_0 925409.KI911562_gene1370 0.0 1626.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1IR3P@117747|Sphingobacteriia 976|Bacteroidetes M Tricorn protease homolog - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ DYD2_k127_851253_8 1189612.A33Q_2872 7.736e-08 54.0 COG3437@1|root,COG3437@2|Bacteria 2|Bacteria T response regulator, receiver - - - - - - - - - - - - Response_reg DYD2_k127_851495_3 1237149.C900_00263 2.152e-44 174.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia 976|Bacteroidetes O PFAM Pregnancy-associated plasma protein-A fpp2 - - - - - - - - - - - Peptidase_M43 DYD2_k127_851495_1 1237149.C900_00262 1.617e-118 391.0 COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,47M8U@768503|Cytophagia 976|Bacteroidetes F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N DYD2_k127_851495_2 1237149.C900_00261 3.358e-90 304.0 COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,47KQI@768503|Cytophagia 976|Bacteroidetes S PFAM PASTA domain spk1 - 2.7.11.1,6.3.2.4 ko:K01921,ko:K08884,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01001,ko01011 - - - PASTA DYD2_k127_851495_0 1237149.C900_00260 1.173e-127 432.0 28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,47JC7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_858123_0 471854.Dfer_1120 3.484e-112 383.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD2_k127_858123_3 1250232.JQNJ01000001_gene3522 1.541e-54 204.0 COG2207@1|root,COG2207@2|Bacteria,4NF8Q@976|Bacteroidetes,1I16E@117743|Flavobacteriia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 DYD2_k127_858123_2 1033802.SSPSH_001573 9.856e-98 334.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC DYD2_k127_858123_1 471854.Dfer_0310 2.219e-110 365.0 COG0656@1|root,COG0656@2|Bacteria,4NK47@976|Bacteroidetes,47MZY@768503|Cytophagia 976|Bacteroidetes S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red DYD2_k127_862522_2 643867.Ftrac_3236 0.0 1015.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 DYD2_k127_862522_7 1380600.AUYN01000001_gene2683 5.2e-197 628.0 COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1I7ZI@117743|Flavobacteriia 976|Bacteroidetes I AMP-binding enzyme - - - - - - - - - - - - AMP-binding DYD2_k127_862522_31 761193.Runsl_1397 2.593e-45 168.0 COG0517@1|root,COG0517@2|Bacteria,4NQYH@976|Bacteroidetes,47QY6@768503|Cytophagia 976|Bacteroidetes S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS DYD2_k127_862522_20 929562.Emtol_1880 1.745e-86 294.0 COG0412@1|root,COG0412@2|Bacteria,4NE8V@976|Bacteroidetes,47KK1@768503|Cytophagia 976|Bacteroidetes Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD2_k127_862522_33 1237149.C900_00817 2.308e-37 146.0 COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,47S2U@768503|Cytophagia 976|Bacteroidetes S DinB family - - - - - - - - - - - - DinB DYD2_k127_862522_8 1237149.C900_00831 9.319e-185 591.0 COG3540@1|root,COG3540@2|Bacteria,4NH1W@976|Bacteroidetes,47KJQ@768503|Cytophagia 976|Bacteroidetes P PhoD-like phosphatase, N-terminal domain phoD - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N DYD2_k127_862522_27 1168034.FH5T_01705 1.661e-65 237.0 COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,2FN2B@200643|Bacteroidia 2|Bacteria F Psort location CytoplasmicMembrane, score 10.00 tqsA - - - - - - - - - - - AI-2E_transport DYD2_k127_862522_30 1250232.JQNJ01000001_gene1474 5.04e-46 174.0 2DBKF@1|root,2Z9SZ@2|Bacteria,4NFPX@976|Bacteroidetes,1HZFY@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_862522_24 1237149.C900_00826 1.107e-75 257.0 2DZGZ@1|root,32VAD@2|Bacteria,4NSFP@976|Bacteroidetes,47RS7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - ATP-synt_10 DYD2_k127_862522_4 1123234.AUKI01000016_gene3077 2.87e-317 992.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1HZDJ@117743|Flavobacteriia 976|Bacteroidetes E Zn_pept - - - - - - - - - - - - Peptidase_M14 DYD2_k127_862522_0 1237149.C900_04538 0.0 1605.0 28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,47M2D@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_862522_21 1124780.ANNU01000015_gene2053 3.421e-85 290.0 COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,47JQR@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA DYD2_k127_862522_17 1237149.C900_04536 4.474e-104 344.0 COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia 976|Bacteroidetes G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM DYD2_k127_862522_34 985255.APHJ01000027_gene884 4.183e-30 124.0 2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1I2EY@117743|Flavobacteriia,2P6WD@244698|Gillisia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_862522_23 1237149.C900_00926 2.428e-78 266.0 COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,47MSF@768503|Cytophagia 976|Bacteroidetes O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 DYD2_k127_862522_1 1237149.C900_00927 0.0 1045.0 COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,47KCK@768503|Cytophagia 976|Bacteroidetes E Aminopeptidase N - - - - - - - - - - - - Peptidase_M1 DYD2_k127_862522_3 1237149.C900_00927 5e-324 1006.0 COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,47KCK@768503|Cytophagia 976|Bacteroidetes E Aminopeptidase N - - - - - - - - - - - - Peptidase_M1 DYD2_k127_862522_5 1237149.C900_00928 2.158e-313 976.0 COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,47KCK@768503|Cytophagia 976|Bacteroidetes E Aminopeptidase N - - - - - - - - - - - - Peptidase_M1 DYD2_k127_862522_12 929562.Emtol_3627 4.266e-129 419.0 COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,47KNZ@768503|Cytophagia 976|Bacteroidetes E Pyridoxal-phosphate dependent enzyme ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD2_k127_862522_25 1124780.ANNU01000006_gene2845 1.72e-73 252.0 COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,47PFV@768503|Cytophagia 976|Bacteroidetes C Nitroreductase family ydjA - - - - - - - - - - - Nitroreductase DYD2_k127_862522_10 1469557.JSWF01000014_gene2626 2.161e-141 459.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1HZRM@117743|Flavobacteriia 976|Bacteroidetes EQ Peptidase family S58 - - - - - - - - - - - - Peptidase_S58 DYD2_k127_862522_15 1265313.HRUBRA_02839 5.087e-116 390.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RPSP@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Glycine betaine opuCC - - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC DYD2_k127_862522_29 314278.NB231_13641 1.754e-59 213.0 COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,1RQWQ@1236|Gammaproteobacteria,1WXWK@135613|Chromatiales 135613|Chromatiales E pfam abc - - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran DYD2_k127_862522_22 929562.Emtol_1416 1.098e-78 270.0 COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K5B@768503|Cytophagia 976|Bacteroidetes H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase DYD2_k127_862522_38 237368.SCABRO_03592 1.1e-10 68.0 2ECCV@1|root,336B4@2|Bacteria,2J3S9@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - DYD2_k127_862522_32 1122603.ATVI01000005_gene3391 8.215e-43 157.0 COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,1SE87@1236|Gammaproteobacteria,1X7YF@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF427) - - - - - - - - - - - - NTP_transf_9 DYD2_k127_862522_13 1305737.JAFX01000001_gene3633 1.421e-124 404.0 COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,47JFN@768503|Cytophagia 976|Bacteroidetes I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase DYD2_k127_862522_36 760192.Halhy_3108 1.967e-19 92.0 COG5646@1|root,COG5646@2|Bacteria,4NW3X@976|Bacteroidetes,1IZMU@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD2_k127_862522_18 153721.MYP_1900 5.465e-100 337.0 COG4335@1|root,COG4335@2|Bacteria,4NH5H@976|Bacteroidetes,47MI7@768503|Cytophagia 976|Bacteroidetes L DNA alkylation repair - - - - - - - - - - - - DNA_alkylation,HEAT DYD2_k127_862522_11 1237149.C900_00841 1.207e-130 446.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD DYD2_k127_862522_6 1120968.AUBX01000012_gene2797 1.932e-284 894.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec DYD2_k127_862522_14 388413.ALPR1_20173 4.347e-122 414.0 COG4796@1|root,COG4796@2|Bacteria,4PM2P@976|Bacteroidetes,47Y0K@768503|Cytophagia 976|Bacteroidetes U Type ii and iii secretion system protein - - - - - - - - - - - - CarbopepD_reg_2,DUF4974,STN DYD2_k127_862522_26 388413.ALPR1_20168 4.901e-66 237.0 COG3712@1|root,COG3712@2|Bacteria,4NMA2@976|Bacteroidetes,47PEK@768503|Cytophagia 976|Bacteroidetes PT Domain of unknown function (DUF4974) - - - - - - - - - - - - DUF4974,FecR DYD2_k127_862522_28 1120968.AUBX01000012_gene2790 9.17e-60 212.0 COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,47PH5@768503|Cytophagia 976|Bacteroidetes K RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_862522_19 946077.W5A_01335 4.179e-95 317.0 COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1HXG3@117743|Flavobacteriia 976|Bacteroidetes P Reversible hydration of carbon dioxide cynT - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA DYD2_k127_862522_9 387092.NIS_0310 6.302e-169 548.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNAQ@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp DYD2_k127_862522_16 644966.Tmar_0705 4.794e-114 389.0 COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,24BT1@186801|Clostridia,3WD7J@538999|Clostridiales incertae sedis 186801|Clostridia S PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD2_k127_862680_0 1237149.C900_02383 3.468e-213 674.0 28KRY@1|root,2ZA9E@2|Bacteria,4NI1H@976|Bacteroidetes,47N4R@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_862680_2 1237149.C900_02382 7.746e-59 208.0 COG0784@1|root,COG0784@2|Bacteria,4NRC9@976|Bacteroidetes,47QC7@768503|Cytophagia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD2_k127_862680_1 1237149.C900_02381 2.784e-96 317.0 COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family pcd - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD2_k127_87931_10 1121904.ARBP01000016_gene5186 1.162e-121 392.0 COG0519@1|root,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia 976|Bacteroidetes F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase DYD2_k127_87931_8 1237149.C900_04417 7.09e-130 435.0 COG0683@1|root,COG0683@2|Bacteria,4PKN8@976|Bacteroidetes,47NJW@768503|Cytophagia 976|Bacteroidetes E PFAM Receptor family ligand binding region - - - - - - - - - - - - Peripla_BP_6 DYD2_k127_87931_5 1237149.C900_04413 1.826e-174 555.0 COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,47K5F@768503|Cytophagia 976|Bacteroidetes Q PFAM Amidohydrolase family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 DYD2_k127_87931_20 1237149.C900_04412 2.139e-34 136.0 COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,47RT6@768503|Cytophagia 976|Bacteroidetes O OsmC-like protein - - - ko:K07397 - - - - ko00000 - - - OsmC DYD2_k127_87931_17 1122621.ATZA01000024_gene2184 7.746e-59 208.0 COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1IS3F@117747|Sphingobacteriia 976|Bacteroidetes F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran DYD2_k127_87931_19 1237149.C900_04409 7.315e-47 175.0 COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes 976|Bacteroidetes S Peptidase S16, lon domain protein - - 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - LON_substr_bdg DYD2_k127_87931_15 391603.FBALC1_06778 2.081e-80 278.0 COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,1HWJW@117743|Flavobacteriia 976|Bacteroidetes Q COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD2_k127_87931_13 1121011.AUCB01000003_gene2515 1.291e-94 316.0 COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,1HXP0@117743|Flavobacteriia,23GNP@178469|Arenibacter 976|Bacteroidetes Q ATPases associated with a variety of cellular activities - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD2_k127_87931_11 616991.JPOO01000003_gene2297 2.955e-108 355.0 COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1HX62@117743|Flavobacteriia,23H53@178469|Arenibacter 976|Bacteroidetes Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD2_k127_87931_0 1237149.C900_04408 0.0 1908.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia 976|Bacteroidetes EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase DYD2_k127_87931_25 553178.CAPGI0001_2334 1.695e-06 59.0 COG3209@1|root,COG3209@2|Bacteria,4PERM@976|Bacteroidetes,1IFB0@117743|Flavobacteriia,1ESN7@1016|Capnocytophaga 976|Bacteroidetes M COG3209 Rhs family protein - - - - - - - - - - - - - DYD2_k127_87931_9 1047013.AQSP01000121_gene2702 1.966e-127 426.0 COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria 2|Bacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD2_k127_87931_3 388413.ALPR1_02295 6.127e-191 610.0 COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47J95@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - Sulfatase DYD2_k127_87931_6 234267.Acid_5053 5.109e-145 471.0 COG0520@1|root,COG0520@2|Bacteria,3Y4TH@57723|Acidobacteria 57723|Acidobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD2_k127_87931_16 1237149.C900_02071 9.668e-71 241.0 COG2030@1|root,COG2030@2|Bacteria,4NNHH@976|Bacteroidetes,47PBK@768503|Cytophagia 976|Bacteroidetes I Acyl dehydratase nodN - - - - - - - - - - - MaoC_dehydratas DYD2_k127_87931_26 278963.ATWD01000001_gene2519 1.734e-05 49.0 2EK70@1|root,33DXD@2|Bacteria,3Y5QD@57723|Acidobacteria,2JK4E@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - DYD2_k127_87931_7 1250006.JHZZ01000001_gene2203 2.97e-132 426.0 COG2159@1|root,COG2159@2|Bacteria,4NJP9@976|Bacteroidetes,1HXKV@117743|Flavobacteriia 976|Bacteroidetes S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD2_k127_87931_24 1122611.KB903943_gene1618 1.797e-09 66.0 29Z9J@1|root,30M7S@2|Bacteria,2I14U@201174|Actinobacteria,4EKXD@85012|Streptosporangiales 201174|Actinobacteria S Protein of unknown function (DUF3592) - - - - - - - - - - - - DUF3592 DYD2_k127_87931_14 313603.FB2170_07649 6.849e-86 289.0 COG4912@1|root,COG4912@2|Bacteria,4NMNG@976|Bacteroidetes,1I1T0@117743|Flavobacteriia 976|Bacteroidetes L DNA alkylation repair enzyme alkD - - - - - - - - - - - DNA_alkylation DYD2_k127_87931_4 1121875.KB907549_gene1707 3.883e-175 571.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 DYD2_k127_87931_18 1121875.KB907548_gene1606 1.564e-56 205.0 28KF8@1|root,2ZA1G@2|Bacteria,4NK7X@976|Bacteroidetes,1I0C7@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_87931_1 1356852.N008_05040 1.401e-278 878.0 COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,47JEM@768503|Cytophagia 976|Bacteroidetes E Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 DYD2_k127_87931_2 1120965.AUBV01000005_gene1764 1.219e-226 715.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes 976|Bacteroidetes S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 DYD2_k127_87931_21 1122176.KB903569_gene3490 5.974e-23 98.0 2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes,1ITQ6@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_882445_12 643867.Ftrac_2194 5.093e-16 84.0 2E0MA@1|root,32W6I@2|Bacteria,4NNWD@976|Bacteroidetes,47Q2K@768503|Cytophagia 976|Bacteroidetes S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 DYD2_k127_882445_1 1237149.C900_05107 0.0 1029.0 COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,4NEYQ@976|Bacteroidetes,47NKP@768503|Cytophagia 976|Bacteroidetes M WD40 repeats - - - - - - - - - - - - WD40 DYD2_k127_882445_0 1237149.C900_05108 0.0 1056.0 COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia 976|Bacteroidetes C - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - HEAT_2,cNMP_binding DYD2_k127_882445_7 1237149.C900_05109 3.723e-52 192.0 COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,47MRT@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane chaperone Skp (OmpH) - - - ko:K06142 - - - - ko00000 - - - OmpH DYD2_k127_882445_4 1237149.C900_05114 5.666e-157 509.0 COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,47JMS@768503|Cytophagia 976|Bacteroidetes S Peptidase, M28 - - - - - - - - - - - - Peptidase_M28 DYD2_k127_882445_5 1237149.C900_05115 7.879e-81 272.0 COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,47PIB@768503|Cytophagia 976|Bacteroidetes S carbonic anhydrase acetyltransferase dapH - - - - - - - - - - - Hexapep DYD2_k127_882445_2 1279009.ADICEAN_02414 2.294e-240 749.0 COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,47MGS@768503|Cytophagia 976|Bacteroidetes J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 DYD2_k127_882445_3 1237149.C900_05119 1.033e-193 611.0 COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,47JXW@768503|Cytophagia 976|Bacteroidetes K sigma54 specific, transcriptional regulator, Fis family fhlA - - - - - - - - - - - HTH_8,Sigma54_activat DYD2_k127_882445_8 1237149.C900_05120 2.542e-37 146.0 2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,47P8C@768503|Cytophagia 976|Bacteroidetes S Lipopolysaccharide-assembly lptE - - - - - - - - - - - LptE DYD2_k127_882445_10 1237149.C900_05121 8.284e-26 119.0 2ECXC@1|root,336UI@2|Bacteria,4NV8T@976|Bacteroidetes,47RWP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_882445_9 1237149.C900_05122 1.809e-27 114.0 COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,47SC6@768503|Cytophagia 976|Bacteroidetes U PFAM Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG DYD2_k127_882445_6 1237149.C900_05123 3.938e-76 261.0 28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_882445_11 1237149.C900_05124 1.655e-16 79.0 COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia 976|Bacteroidetes O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD2_k127_88620_7 1150600.ADIARSV_1078 4.241e-21 93.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1ISDK@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - - - - - - - - - - HTH_18 DYD2_k127_88620_0 760192.Halhy_5663 1.019e-274 861.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - CHASE3,Guanylate_cyc,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12 DYD2_k127_88620_3 1131812.JQMS01000001_gene2389 7.85e-68 232.0 COG2204@1|root,COG2204@2|Bacteria,4NR03@976|Bacteroidetes,1IKSJ@117743|Flavobacteriia,2P0VE@237|Flavobacterium 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD2_k127_88620_2 378806.STAUR_3895 5.567e-69 241.0 COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,1R85W@1224|Proteobacteria 1224|Proteobacteria M Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - Big_5,DUF3494,VPEP DYD2_k127_88620_4 1122176.KB903532_gene2680 1.194e-65 230.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1IQFC@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,OmpA,PD40 DYD2_k127_88620_6 435591.BDI_3213 1.102e-22 105.0 COG0810@1|root,COG0810@2|Bacteria,4NW2E@976|Bacteroidetes,2FWGT@200643|Bacteroidia,230RW@171551|Porphyromonadaceae 976|Bacteroidetes M Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - Peptidase_M56,TonB_C DYD2_k127_88620_8 1121887.AUDK01000030_gene2293 2.427e-18 89.0 2CFVU@1|root,3373K@2|Bacteria,4NY6U@976|Bacteroidetes,1ID3F@117743|Flavobacteriia,2NX5E@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_88620_9 1189619.pgond44_02393 1.16e-14 76.0 2EFZF@1|root,339RM@2|Bacteria,4PA57@976|Bacteroidetes,1I6WD@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_88620_5 1189619.pgond44_02383 1.911e-45 167.0 COG1917@1|root,COG1917@2|Bacteria,4NSB6@976|Bacteroidetes,1I4FM@117743|Flavobacteriia 976|Bacteroidetes S Cupin domain protein - - - - - - - - - - - - Cupin_2 DYD2_k127_88620_10 1168034.FH5T_15540 8.874e-12 66.0 2DFUX@1|root,2ZT8Y@2|Bacteria,4P92B@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_88620_1 269798.CHU_0232 1.831e-113 382.0 COG3420@1|root,COG5184@1|root,COG3420@2|Bacteria,COG5184@2|Bacteria,4NMRB@976|Bacteroidetes,47QVY@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF3494) - - - - - - - - - - - - Big_5,DUF3494 DYD2_k127_890915_2 1237149.C900_05813 2.087e-62 224.0 COG0438@1|root,COG0438@2|Bacteria,4NMMT@976|Bacteroidetes,47PDF@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 DYD2_k127_890915_0 883096.HMPREF9699_01656 3.197e-137 439.0 COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1HWTI@117743|Flavobacteriia 976|Bacteroidetes E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 DYD2_k127_890915_1 1237149.C900_05815 2.187e-88 300.0 2DBU8@1|root,2ZB4S@2|Bacteria,4PKQU@976|Bacteroidetes,47Y2Z@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 DYD2_k127_890915_3 1158318.ATXC01000002_gene1571 1.151e-39 150.0 COG1970@1|root,COG1970@2|Bacteria 2|Bacteria M mechanosensitive ion channel activity mscL GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL DYD2_k127_890915_4 388413.ALPR1_11035 1.484e-26 108.0 COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,47NRU@768503|Cytophagia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N DYD2_k127_949228_16 663610.JQKO01000001_gene802 1.301e-10 61.0 COG3387@1|root,COG3387@2|Bacteria,1R65A@1224|Proteobacteria,2U210@28211|Alphaproteobacteria,3NA5M@45404|Beijerinckiaceae 28211|Alphaproteobacteria G Glycosyl hydrolases family 15 - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - Glyco_hydro_15 DYD2_k127_949228_4 1237149.C900_05632 3.999e-129 428.0 COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia 976|Bacteroidetes S Peptidase family C25 - - - - - - - - - - - - CARDB,FlgD_ig,ILEI,Peptidase_C25 DYD2_k127_949228_11 1237149.C900_05630 4.3e-50 180.0 COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,47Q8F@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR DYD2_k127_949228_0 1237149.C900_05629 4.459e-216 695.0 COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,47M43@768503|Cytophagia 976|Bacteroidetes KT PFAM PspC domain - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - DUF2807,PspC DYD2_k127_949228_3 1237149.C900_00208 6.186e-175 559.0 COG1236@1|root,COG1236@2|Bacteria,4NESD@976|Bacteroidetes,47K9F@768503|Cytophagia 976|Bacteroidetes J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL DYD2_k127_949228_15 1048983.EL17_05560 1.157e-12 74.0 2E80N@1|root,332EV@2|Bacteria,4NW5E@976|Bacteroidetes,47S8Q@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_949228_13 1048983.EL17_05560 8.044e-31 126.0 2E80N@1|root,332EV@2|Bacteria,4NW5E@976|Bacteroidetes,47S8Q@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_949228_8 1237149.C900_00381 1.249e-72 249.0 COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47PTY@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD2_k127_949228_7 1237149.C900_00383 2.109e-73 259.0 COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,47Y4X@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - - - - - - - - - - - OMP_b-brl_2 DYD2_k127_949228_6 1237149.C900_04820 1.501e-88 297.0 COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - TetR_C_4,TetR_C_5,TetR_N DYD2_k127_949228_2 1237149.C900_04821 9.851e-198 618.0 COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,47TVD@768503|Cytophagia 976|Bacteroidetes S Phenylacetic acid catabolic protein paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC DYD2_k127_949228_9 1237149.C900_04822 4.141e-67 234.0 COG3460@1|root,COG3460@2|Bacteria 2|Bacteria Q phenylacetate catabolic process paaB - - ko:K02610 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - PaaB DYD2_k127_949228_5 1237149.C900_04823 3.213e-125 405.0 COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,47VWV@768503|Cytophagia 976|Bacteroidetes S Phenylacetic acid catabolic protein paaC - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC DYD2_k127_949228_12 1408813.AYMG01000036_gene3265 1.756e-37 146.0 COG0454@1|root,COG0456@2|Bacteria,4NURB@976|Bacteroidetes,1IU7H@117747|Sphingobacteriia 976|Bacteroidetes K DinB superfamily - - - - - - - - - - - - DinB_2 DYD2_k127_949228_10 1237149.C900_04824 4.956e-59 208.0 COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes 976|Bacteroidetes L Phenylacetate-CoA oxygenase paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P DYD2_k127_949228_1 485917.Phep_0666 1.67e-213 676.0 COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia 976|Bacteroidetes L Belongs to the DEAD box helicase family deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C DYD2_k127_949228_14 1521187.JPIM01000167_gene1704 9.936e-21 96.0 COG0457@1|root,COG1404@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia 32061|Chloroflexia O PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - Kelch_4,Kelch_5,Peptidase_S8 DYD2_k127_959_4 1237149.C900_03967 6.91e-194 610.0 COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,47MUV@768503|Cytophagia 976|Bacteroidetes O magnesium chelatase comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C DYD2_k127_959_15 929703.KE386491_gene2534 7.233e-80 270.0 COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,47KZ6@768503|Cytophagia 976|Bacteroidetes G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 DYD2_k127_959_2 1237149.C900_03964 3.065e-230 729.0 COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region msbA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD2_k127_959_3 1237149.C900_03963 9.34e-204 651.0 2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47JNN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Caps_assemb_Wzi DYD2_k127_959_23 643867.Ftrac_2619 3.744e-36 138.0 COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,47R60@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 DYD2_k127_959_8 1048983.EL17_13365 1.101e-167 535.0 COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,47XWC@768503|Cytophagia 976|Bacteroidetes M Sugar nucleotidyl transferase glmU - - - - - - - - - - - NTP_transf_4 DYD2_k127_959_12 1237149.C900_03960 5.198e-119 397.0 COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,47XWD@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III, delta' subunit holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 DYD2_k127_959_14 1237149.C900_03958 7.772e-90 305.0 COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia 976|Bacteroidetes O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase DYD2_k127_959_13 1237149.C900_03957 3.809e-115 377.0 COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,47MQV@768503|Cytophagia 976|Bacteroidetes M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind DYD2_k127_959_9 866536.Belba_0318 3.254e-165 531.0 COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,47NFV@768503|Cytophagia 976|Bacteroidetes U Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD2_k127_959_11 309807.SRU_0899 6.142e-133 437.0 COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,1FJPU@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD2_k127_959_7 1237149.C900_03939 6.781e-171 552.0 COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,47JP2@768503|Cytophagia 976|Bacteroidetes P type I phosphodiesterase nucleotide pyrophosphatase pafA - - - - - - - - - - - Phosphodiest DYD2_k127_959_10 1237149.C900_03938 1.14e-133 458.0 COG1729@1|root,COG1729@2|Bacteria,4PP99@976|Bacteroidetes,47VYS@768503|Cytophagia 976|Bacteroidetes S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - WG_beta_rep DYD2_k127_959_24 1286632.P278_20690 9.304e-20 100.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp DYD2_k127_959_20 616991.JPOO01000001_gene4570 1.629e-55 205.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia 976|Bacteroidetes T Universal stress protein uspA - - - - - - - - - - - DUF2007,Usp DYD2_k127_959_6 1123277.KB893181_gene2302 3.006e-173 553.0 COG0738@1|root,COG0738@2|Bacteria,4NHI6@976|Bacteroidetes,47KNG@768503|Cytophagia 976|Bacteroidetes G PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD2_k127_959_5 929562.Emtol_2633 2.539e-187 598.0 COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,47JY4@768503|Cytophagia 976|Bacteroidetes G PFAM Glycoside hydrolase, family 37 treA - 3.2.1.28 ko:K01194 ko00500,ko01100,map00500,map01100 - R00010 RC00049 ko00000,ko00001,ko00537,ko01000 - GH37 - Trehalase DYD2_k127_959_16 1237149.C900_05423 6.219e-74 254.0 2BBSK@1|root,325AS@2|Bacteria,4NR2Q@976|Bacteroidetes,47JP3@768503|Cytophagia 976|Bacteroidetes S CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 DYD2_k127_959_21 1237149.C900_05422 3.45e-48 175.0 COG0640@1|root,COG0640@2|Bacteria,4NRN0@976|Bacteroidetes,47QVI@768503|Cytophagia 976|Bacteroidetes K arsR family arsR - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 DYD2_k127_959_18 643867.Ftrac_1841 1.025e-62 222.0 COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,47Q1Q@768503|Cytophagia 976|Bacteroidetes S haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E yjjG - - ko:K07025 - - - - ko00000 - - - HAD_2 DYD2_k127_959_1 1237149.C900_05420 3.75e-291 900.0 COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia 976|Bacteroidetes C TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 pruA - 1.2.1.88,1.5.5.2 ko:K00294,ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh DYD2_k127_959_19 204669.Acid345_1957 1.034e-57 206.0 COG4430@1|root,COG4430@2|Bacteria,3Y5HF@57723|Acidobacteria,2JMZY@204432|Acidobacteriia 204432|Acidobacteriia S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA DYD2_k127_959_0 1237149.C900_05718 0.0 1451.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 DYD2_k127_959_17 1237149.C900_05719 3.65e-67 237.0 COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia 976|Bacteroidetes H PFAM Biotin lipoate A B protein ligase birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_LplA_LipB DYD2_k127_959_22 1237149.C900_05720 6.793e-47 171.0 COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia 976|Bacteroidetes S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD2_k127_959_25 1121904.ARBP01000018_gene2600 1.017e-05 47.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,47KKF@768503|Cytophagia 976|Bacteroidetes O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD2_k127_970380_10 992406.RIA_1586 3.172e-80 270.0 COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,1HXN9@117743|Flavobacteriia 976|Bacteroidetes Q Fumarylacetoacetase fahA - 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FAA_hydrolase,FAA_hydrolase_N DYD2_k127_970380_6 1237149.C900_04903 1.255e-120 392.0 COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,47KXZ@768503|Cytophagia 976|Bacteroidetes S PFAM Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct DYD2_k127_970380_3 1237149.C900_04385 1.099e-182 574.0 COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,47J9X@768503|Cytophagia 976|Bacteroidetes C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD2_k127_970380_1 1237149.C900_04383 3.601e-221 700.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,47KBE@768503|Cytophagia 976|Bacteroidetes M Tetratricopeptide repeat protein - - - - - - - - - - - - OmpA,TPR_16,TPR_2,TPR_8 DYD2_k127_970380_14 1237149.C900_04382 4.779e-30 120.0 COG1983@1|root,COG1983@2|Bacteria,4NUNU@976|Bacteroidetes,47RWN@768503|Cytophagia 976|Bacteroidetes KT PFAM PspC domain - - - - - - - - - - - - PspC DYD2_k127_970380_8 926549.KI421517_gene3855 9.18e-116 381.0 COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,47K2G@768503|Cytophagia 976|Bacteroidetes S PFAM Glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 DYD2_k127_970380_15 1356852.N008_19910 6.989e-30 121.0 COG0718@1|root,COG0718@2|Bacteria,4NQ37@976|Bacteroidetes,47R3V@768503|Cytophagia 976|Bacteroidetes S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd DYD2_k127_970380_7 1237149.C900_04378 5.657e-119 405.0 COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C DYD2_k127_970380_0 1237149.C900_04377 5.013e-225 706.0 COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,47MP5@768503|Cytophagia 976|Bacteroidetes E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic DYD2_k127_970380_4 1237149.C900_04376 2.692e-161 526.0 COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,47KPD@768503|Cytophagia 976|Bacteroidetes J tRNA synthetase class II core domain (G, H, P, S and T) hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD2_k127_970380_11 1237149.C900_04374 2.222e-71 244.0 COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,47QNZ@768503|Cytophagia 976|Bacteroidetes S TIGRFAM phosphoesterase, MJ0936 family - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 DYD2_k127_970380_12 1121875.KB907549_gene1856 5.917e-60 212.0 COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1HZPZ@117743|Flavobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 DYD2_k127_970380_5 616991.JPOO01000003_gene644 1.905e-153 492.0 COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1HZPZ@117743|Flavobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 DYD2_k127_970380_2 1250232.JQNJ01000001_gene238 5.281e-188 600.0 COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1HYG1@117743|Flavobacteriia 976|Bacteroidetes E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD2_k127_970380_9 580332.Slit_1984 1.41e-85 287.0 COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD2_k127_970380_13 1189612.A33Q_4532 9.053e-41 155.0 COG2259@1|root,COG2259@2|Bacteria,4NP94@976|Bacteroidetes,47QI2@768503|Cytophagia 976|Bacteroidetes S DoxX - - - - - - - - - - - - DoxX DYD2_k127_980611_3 1286632.P278_06290 3.424e-22 104.0 2C3TU@1|root,2ZBKB@2|Bacteria,4NMMF@976|Bacteroidetes,1I1HI@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD2_k127_980611_1 468059.AUHA01000008_gene2740 1.249e-80 273.0 COG0177@1|root,COG0177@2|Bacteria,4NMJS@976|Bacteroidetes,1IVII@117747|Sphingobacteriia 976|Bacteroidetes L PFAM HhH-GPD superfamily base excision DNA repair protein - - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD DYD2_k127_980611_0 1538295.JY96_15065 1.413e-178 584.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KJ3Z@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein iorB2 - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD2_k127_980611_2 314285.KT71_06354 2.012e-59 209.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,1J7T4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 DYD2_k127_980611_4 313596.RB2501_04510 0.0007 43.0 2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia 976|Bacteroidetes S TIR domain - - - - - - - - - - - - TIR_2 DYD2_k127_98492_0 1237149.C900_04864 2.218e-265 825.0 COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,47JMH@768503|Cytophagia 976|Bacteroidetes L PFAM UvrD REP helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD2_k127_98492_9 436308.Nmar_1159 0.0006045 51.0 arCOG08191@1|root,arCOG08191@2157|Archaea 2157|Archaea S Protein of unknown function, DUF488 - - - - - - - - - - - - - DYD2_k127_98492_2 1237149.C900_04861 1.175e-85 287.0 COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,47NCP@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3109) - - - - - - - - - - - - DUF3109 DYD2_k127_98492_5 1237149.C900_05222 1.911e-58 206.0 COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,47PY1@768503|Cytophagia 976|Bacteroidetes J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N DYD2_k127_98492_7 1237149.C900_05223 2.17e-37 142.0 COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,47R23@768503|Cytophagia 976|Bacteroidetes J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 DYD2_k127_98492_6 1237149.C900_05224 4.697e-52 186.0 COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,47QQD@768503|Cytophagia 976|Bacteroidetes J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 DYD2_k127_98492_1 1237149.C900_05228 5.583e-102 343.0 COG1196@1|root,COG1196@2|Bacteria,4NHAC@976|Bacteroidetes,47MGD@768503|Cytophagia 976|Bacteroidetes D nuclear chromosome segregation - - - ko:K09892 - - - - ko00000,ko03036 - - - - DYD2_k127_98492_4 1237149.C900_05946 3.587e-63 226.0 COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,47N8Y@768503|Cytophagia 976|Bacteroidetes S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 DYD2_k127_98492_3 1237149.C900_05945 2.103e-64 222.0 COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,47PP3@768503|Cytophagia 976|Bacteroidetes P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 DYD2_k127_98492_8 1121129.KB903371_gene244 3.431e-16 79.0 COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,2FM57@200643|Bacteroidia,22WGA@171551|Porphyromonadaceae 976|Bacteroidetes L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG ## 3029 queries scanned ## Total time (seconds): 9.506717205047607 ## Rate: 318.62 q/s