## Mon Feb 16 14:33:03 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/DYD2_bin.55.fa -m mmseqs --output DYD2_bin.55 --output_dir /data/result/bins/wyx/eggqs50+/DYD2_bin.55 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DYD2_k127_1147056_4	1459636.NTE_03244	3.459e-135	436.0	COG1237@1|root,arCOG00503@2157|Archaea	2157|Archaea	S	PFAM beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Lactamase_B_2
DYD2_k127_1147056_7	1229909.NSED_05375	7.99e-102	336.0	arCOG02703@1|root,arCOG02703@2157|Archaea	2157|Archaea	S	Methyltransferase type 11	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
DYD2_k127_1147056_20	1229909.NSED_00780	9.006e-30	119.0	COG0526@1|root,arCOG01218@2157|Archaea	2157|Archaea	CO	TIGRFAM Glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
DYD2_k127_1147056_29	1229909.NSED_00785	3.049e-13	72.0	arCOG04508@1|root,arCOG04508@2157|Archaea	1229909.NSED_00785|-	P	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_3	436308.Nmar_1144	2.999e-145	466.0	COG0785@1|root,arCOG02398@2157|Archaea	2157|Archaea	O	cytochrome c biogenesis protein	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DYD2_k127_1147056_27	1229909.NSED_06840	7.543e-16	83.0	COG4263@1|root,arCOG06217@2157|Archaea	2157|Archaea	C	Cytochrome C oxidase, subunit II	nosZ	-	1.7.2.4,1.9.3.1	ko:K00376,ko:K02275	ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120	M00155,M00529	R00081,R02804	RC00016,RC02861	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1,TAT_signal
DYD2_k127_1147056_24	1229909.NSED_07715	2.258e-18	90.0	arCOG10581@1|root,arCOG10581@2157|Archaea,41T5S@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_30	1229909.NSED_07990	7.431e-10	61.0	arCOG14602@1|root,arCOG14602@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_28	1459636.NTE_03342	1.399e-15	86.0	arCOG10350@1|root,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_31	1229909.NSED_05825	5.845e-09	66.0	arCOG10350@1|root,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_8	1131266.ARWQ01000029_gene982	2.083e-88	309.0	arCOG08793@1|root,arCOG08793@2157|Archaea,41TBC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_16	1459636.NTE_01477	5.848e-40	151.0	COG1970@1|root,arCOG05213@2157|Archaea	2157|Archaea	M	Large-conductance mechanosensitive channel, MscL	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
DYD2_k127_1147056_21	436308.Nmar_0710	2.122e-28	116.0	COG1522@1|root,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD2_k127_1147056_14	1229909.NSED_03670	4.928e-46	169.0	arCOG10535@1|root,arCOG10535@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_19	1229909.NSED_03675	2.469e-32	128.0	arCOG08660@1|root,arCOG08660@2157|Archaea,41T60@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_10	436308.Nmar_0713	5.839e-67	231.0	arCOG10536@1|root,arCOG10536@2157|Archaea	2157|Archaea	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DYD2_k127_1147056_5	1229909.NSED_03685	3.925e-129	426.0	arCOG05201@1|root,arCOG05201@2157|Archaea	2157|Archaea	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_9	436308.Nmar_0715	1.066e-71	243.0	COG1310@1|root,arCOG01139@2157|Archaea,41SQ7@651137|Thaumarchaeota	651137|Thaumarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
DYD2_k127_1147056_17	1131266.ARWQ01000002_gene624	1.261e-39	150.0	arCOG08750@1|root,arCOG08750@2157|Archaea,41SSB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_23	1131266.ARWQ01000002_gene623	4.785e-26	111.0	arCOG08751@1|root,arCOG08751@2157|Archaea,41SS7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_0	1229909.NSED_03705	1.136e-237	740.0	COG1173@1|root,arCOG00749@2157|Archaea,41SFE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DYD2_k127_1147056_1	436308.Nmar_0719	1.316e-191	601.0	COG0601@1|root,arCOG00751@2157|Archaea,41S7B@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DYD2_k127_1147056_15	1229909.NSED_03725	4.788e-43	157.0	arCOG10537@1|root,arCOG10537@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_12	1229909.NSED_03735	4.204e-63	230.0	arCOG08796@1|root,arCOG08796@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_2	1229909.NSED_03865	1.302e-166	536.0	arCOG08796@1|root,arCOG08796@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_13	1229909.NSED_02340	2.156e-54	194.0	COG0454@1|root,arCOG00826@2157|Archaea	2157|Archaea	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD2_k127_1147056_22	436308.Nmar_1778	8.108e-28	121.0	arCOG08685@1|root,arCOG08685@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_26	1131266.ARWQ01000001_gene1167	4.72e-16	89.0	arCOG08033@1|root,arCOG08643@1|root,arCOG08033@2157|Archaea,arCOG08643@2157|Archaea,41T3A@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_6	436308.Nmar_0724	2.667e-120	389.0	arCOG05906@1|root,arCOG05906@2157|Archaea,41T21@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1147056_11	436308.Nmar_0726	6.06e-65	223.0	COG0553@1|root,arCOG00883@2157|Archaea,41T0G@651137|Thaumarchaeota	651137|Thaumarchaeota	K	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
DYD2_k127_1150658_3	1229909.NSED_08035	7.043e-30	119.0	COG0720@1|root,arCOG02172@2157|Archaea,41SY8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DYD2_k127_1150658_2	1229909.NSED_08030	1.017e-48	174.0	COG2154@1|root,arCOG02939@2157|Archaea,41SSQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
DYD2_k127_1150658_1	1229909.NSED_08025	1.577e-126	409.0	COG0367@1|root,arCOG00071@2157|Archaea,41SIX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
DYD2_k127_1150658_0	1229909.NSED_08020	3.106e-260	805.0	COG0015@1|root,arCOG01747@2157|Archaea,41SD1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	adenylosuccinate lyase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
DYD2_k127_1156514_0	1229909.NSED_04250	6.263e-204	642.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
DYD2_k127_1156514_3	1131266.ARWQ01000002_gene611	4.719e-23	101.0	arCOG10538@1|root,arCOG10538@2157|Archaea,41T9G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1156514_2	1229909.NSED_04045	6.515e-36	138.0	COG0011@1|root,arCOG04373@2157|Archaea,41T99@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
DYD2_k127_1156514_1	1229909.NSED_04040	1.379e-69	237.0	COG1060@1|root,arCOG00656@2157|Archaea,41SEG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DYD2_k127_1176936_0	436308.Nmar_0242	0.0	1260.0	COG1241@1|root,arCOG00439@2157|Archaea,41SA7@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Belongs to the MCM family	-	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	MCM,MCM_N,MCM_OB
DYD2_k127_1176936_1	436308.Nmar_0240	2.011e-177	560.0	COG0470@1|root,arCOG00469@2157|Archaea,41SFJ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Replication factor C	-	-	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	DNA_pol3_delta2,Rep_fac_C,RuvB_N
DYD2_k127_1191591_2	436308.Nmar_1243	4.421e-159	503.0	COG0433@1|root,arCOG00280@2157|Archaea,41SE3@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
DYD2_k127_1191591_1	436308.Nmar_1244	4.987e-198	621.0	COG0420@1|root,arCOG00397@2157|Archaea,41S68@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos_2
DYD2_k127_1191591_0	436308.Nmar_1245	2.569e-309	960.0	COG0419@1|root,COG1122@1|root,arCOG00202@2157|Archaea,arCOG00368@2157|Archaea,41S9P@651137|Thaumarchaeota	651137|Thaumarchaeota	LP	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15
DYD2_k127_1191591_7	436308.Nmar_1660	2.122e-38	155.0	arCOG08113@1|root,arCOG08113@2157|Archaea	2157|Archaea	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1191591_4	1229909.NSED_01440	1.88e-90	300.0	COG0727@1|root,arCOG02579@2157|Archaea	2157|Archaea	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DYD2_k127_1191591_10	1459636.NTE_02806	0.0007318	42.0	arCOG10404@1|root,arCOG10404@2157|Archaea	1459636.NTE_02806|-	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1191591_6	1229909.NSED_05070	9.862e-47	169.0	COG0607@1|root,arCOG02021@2157|Archaea	2157|Archaea	P	COG0607 Rhodanese-related sulfurtransferase	-	-	2.8.1.11	ko:K03406,ko:K21028	ko02020,ko02030,ko04122,map02020,map02030,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko02035	-	-	-	MCPsignal,Pyr_redox_2,Pyr_redox_dim,Rhodanese
DYD2_k127_1191591_8	436308.Nmar_1250	7.023e-38	162.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Kazal_1
DYD2_k127_1191591_3	1229909.NSED_06400	6.459e-143	473.0	COG3794@1|root,arCOG08764@1|root,arCOG02926@2157|Archaea,arCOG08764@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD2_k127_1191591_9	1123059.KB823011_gene1000	3.922e-07	63.0	2DSXQ@1|root,33HVC@2|Bacteria,1N9KU@1224|Proteobacteria,2TWFA@28211|Alphaproteobacteria,43YJZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1
DYD2_k127_1191591_5	436308.Nmar_1251	8.585e-82	274.0	arCOG04006@1|root,arCOG04006@2157|Archaea,41SKF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PBS lyase HEAT-like repeat	-	-	1.14.99.29	ko:K06072	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2
DYD2_k127_1192282_10	1459636.NTE_00865	2.88e-06	49.0	COG0306@1|root,arCOG02267@2157|Archaea,41SD8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DYD2_k127_1192282_7	436308.Nmar_0488	3.185e-52	187.0	COG0394@1|root,arCOG04425@2157|Archaea,41T49@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
DYD2_k127_1192282_5	1229909.NSED_02445	2.802e-108	353.0	COG0580@1|root,arCOG04431@2157|Archaea,41SJI@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Major Intrinsic Protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DYD2_k127_1192282_1	436308.Nmar_0490	2.41e-232	723.0	COG0001@1|root,arCOG00918@2157|Archaea,41SDE@651137|Thaumarchaeota	651137|Thaumarchaeota	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DYD2_k127_1192282_2	1229909.NSED_02460	4.835e-153	488.0	COG0181@1|root,arCOG04299@2157|Archaea,41S6Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
DYD2_k127_1192282_3	1229909.NSED_02465	5.389e-142	453.0	COG0007@1|root,arCOG00644@2157|Archaea,41S9J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
DYD2_k127_1192282_4	436308.Nmar_0493	5.068e-132	424.0	COG1587@1|root,arCOG02048@2157|Archaea,41SN2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
DYD2_k127_1192282_6	1278073.MYSTI_04410	7.236e-79	289.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36,Peptidase_M6
DYD2_k127_1192282_9	1229909.NSED_00425	5.82e-11	64.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
DYD2_k127_1192282_0	436308.Nmar_0495	1.201e-296	911.0	COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
DYD2_k127_1192282_8	1229909.NSED_02485	2.047e-44	163.0	COG0719@1|root,arCOG01715@2157|Archaea,41S7W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufD	-	-	-	ko:K09014,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
DYD2_k127_1197631_4	436308.Nmar_1386	2.111e-15	76.0	COG0468@1|root,arCOG00415@2157|Archaea,41SBA@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
DYD2_k127_1197631_3	436308.Nmar_1387	3.206e-29	116.0	COG4919@1|root,arCOG04293@2157|Archaea,41SVI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein S30	-	-	-	ko:K02983	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04121	-	-	-	Ribosomal_S30
DYD2_k127_1197631_0	436308.Nmar_1388	0.0	1142.0	COG1032@1|root,arCOG01357@2157|Archaea,41SCX@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DYD2_k127_1197631_2	1131266.ARWQ01000004_gene1493	1.871e-131	423.0	COG0543@1|root,arCOG02199@2157|Archaea,41SY5@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
DYD2_k127_1197631_1	436308.Nmar_1390	9.824e-171	538.0	COG0167@1|root,arCOG00603@2157|Archaea	2157|Archaea	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1	ko:K00226,ko:K00254,ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R01868,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DYD2_k127_1217687_3	1229909.NSED_09790	2.477e-40	149.0	COG3432@1|root,arCOG01055@2157|Archaea,41T3P@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
DYD2_k127_1217687_1	436308.Nmar_0034	9.004e-118	388.0	COG2512@1|root,arCOG00374@2157|Archaea,41SUX@651137|Thaumarchaeota	651137|Thaumarchaeota	K	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1217687_4	436308.Nmar_0036	1.559e-27	113.0	arCOG08815@1|root,arCOG08815@2157|Archaea,41T9N@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1217687_0	436308.Nmar_0037	1.199e-128	413.0	COG0602@1|root,arCOG02173@2157|Archaea,41SGM@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Radical_SAM
DYD2_k127_1217687_2	436308.Nmar_0038	1.935e-63	220.0	COG0302@1|root,arCOG04542@2157|Archaea,41SGC@651137|Thaumarchaeota	651137|Thaumarchaeota	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
DYD2_k127_1234955_2	436308.Nmar_0736	5.063e-37	142.0	arCOG08802@1|root,arCOG08802@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1234955_1	436308.Nmar_0737	3.889e-59	210.0	COG0484@1|root,arCOG02846@2157|Archaea,41T68@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
DYD2_k127_1234955_0	436308.Nmar_0738	1.797e-70	240.0	COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
DYD2_k127_1234955_3	436308.Nmar_0739	7.39e-30	120.0	COG0457@1|root,arCOG03032@2157|Archaea,41T66@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1
DYD2_k127_1258517_4	436308.Nmar_0037	9.985e-99	324.0	COG0602@1|root,arCOG02173@2157|Archaea,41SGM@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Radical_SAM
DYD2_k127_1258517_3	436308.Nmar_0038	9.393e-100	329.0	COG0302@1|root,arCOG04542@2157|Archaea,41SGC@651137|Thaumarchaeota	651137|Thaumarchaeota	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
DYD2_k127_1258517_5	1229909.NSED_09820	1.071e-35	136.0	arCOG08816@1|root,arCOG08816@2157|Archaea,41TAW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1258517_2	436308.Nmar_0040	2.471e-125	403.0	COG0603@1|root,arCOG00039@2157|Archaea,41SGR@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Queuosine biosynthesis protein QueC	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
DYD2_k127_1258517_0	436308.Nmar_0041	6.449e-156	496.0	COG0083@1|root,arCOG01027@2157|Archaea,41S89@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DYD2_k127_1258517_1	1229909.NSED_09835	3.673e-133	427.0	COG1100@1|root,arCOG01225@2157|Archaea,41T0A@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
DYD2_k127_128398_2	1229909.NSED_09280	5.128e-68	234.0	arCOG10601@1|root,arCOG10601@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_128398_4	1459636.NTE_02466	1.301e-16	80.0	arCOG11612@1|root,arCOG11612@2157|Archaea,41T8D@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_128398_3	436308.Nmar_1742	4.772e-28	113.0	arCOG07262@1|root,arCOG07262@2157|Archaea,41T8B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_128398_0	1229909.NSED_09265	3.334e-84	289.0	arCOG08768@1|root,arCOG08768@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_128398_1	436308.Nmar_1740	1.452e-83	278.0	COG0652@1|root,arCOG04767@2157|Archaea,41T32@651137|Thaumarchaeota	651137|Thaumarchaeota	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DYD2_k127_1315719_9	1229909.NSED_07810	6.05e-17	80.0	arCOG08687@1|root,arCOG08687@2157|Archaea,41SVF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1315719_6	1229909.NSED_07805	7.062e-48	174.0	arCOG10584@1|root,arCOG10584@2157|Archaea,41SV6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial Fe(2+) trafficking	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
DYD2_k127_1315719_4	1229909.NSED_07800	5.586e-70	239.0	arCOG08772@1|root,arCOG08772@2157|Archaea,41SSX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1315719_0	1229909.NSED_07795	1.076e-190	598.0	COG0104@1|root,arCOG04387@2157|Archaea,41SCA@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
DYD2_k127_1315719_7	1459636.NTE_00654	4.927e-44	168.0	arCOG08773@1|root,arCOG08773@2157|Archaea,41SNY@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1315719_3	1229909.NSED_07785	2.859e-130	418.0	COG0284@1|root,arCOG00081@2157|Archaea,41SMN@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
DYD2_k127_1315719_8	1459636.NTE_00652	6.029e-36	140.0	COG0494@1|root,arCOG01078@2157|Archaea,41SPS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DYD2_k127_1315719_2	436308.Nmar_1416	2.522e-150	477.0	COG0020@1|root,arCOG01532@2157|Archaea,41S8J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids	uppS	-	2.5.1.89	ko:K15888	ko00900,map00900	-	R09730	RC00279,RC02839	ko00000,ko00001,ko01000	-	-	-	Prenyltransf
DYD2_k127_1315719_1	1229909.NSED_07770	7.637e-190	598.0	COG2237@1|root,arCOG04151@2157|Archaea,41SA3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
DYD2_k127_1315719_5	1229909.NSED_07765	2.648e-60	212.0	arCOG08774@1|root,arCOG08774@2157|Archaea,41T7U@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1315719_10	1229909.NSED_07760	1.943e-16	79.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1384828_3	1229909.NSED_09040	1.1e-53	188.0	COG0004@1|root,arCOG04397@2157|Archaea,41SY0@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
DYD2_k127_1384828_1	1229909.NSED_09030	3.247e-151	481.0	COG2897@1|root,arCOG02019@2157|Archaea,41SXR@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
DYD2_k127_1384828_0	1229909.NSED_09015	0.0	1188.0	COG1269@1|root,arCOG04138@2157|Archaea,41SRH@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
DYD2_k127_1384828_2	1229909.NSED_09010	1.038e-79	270.0	COG1390@1|root,arCOG00869@2157|Archaea,41T4W@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
DYD2_k127_1522597_9	1229909.NSED_03715	1.513e-15	75.0	arCOG03272@1|root,arCOG03272@2157|Archaea,41T3V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1522597_8	1229909.NSED_03720	2.483e-22	98.0	COG4895@1|root,arCOG04920@2157|Archaea	2157|Archaea	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
DYD2_k127_1522597_11	1131266.ARWQ01000004_gene1399	1.051e-13	72.0	28HBE@1|root,2N5BC@2157|Archaea,41T8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1522597_6	1229909.NSED_06795	5.74e-29	117.0	arCOG10408@1|root,arCOG10408@2157|Archaea,41T82@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1522597_4	436308.Nmar_1194	3.513e-63	220.0	arCOG08693@1|root,arCOG08693@2157|Archaea,41T7N@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1522597_5	1229909.NSED_06805	6.249e-32	125.0	arCOG10579@1|root,arCOG10579@2157|Archaea,41TAI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1522597_2	436308.Nmar_1196	1.237e-106	349.0	arCOG08694@1|root,arCOG08694@2157|Archaea,41SZ1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1522597_7	1229909.NSED_06820	1.677e-26	110.0	COG1522@1|root,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD2_k127_1522597_1	1229909.NSED_06825	4.512e-187	591.0	COG0585@1|root,arCOG04252@2157|Archaea,41S7C@651137|Thaumarchaeota	651137|Thaumarchaeota	J	tRNA pseudouridine synthase	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
DYD2_k127_1522597_0	1229909.NSED_06830	2.928e-209	662.0	COG4257@1|root,arCOG03564@2157|Archaea,41SM7@651137|Thaumarchaeota	651137|Thaumarchaeota	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
DYD2_k127_1522597_3	436308.Nmar_1200	8.865e-69	236.0	COG1990@1|root,arCOG04228@2157|Archaea,41ST1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Peptidyl-tRNA hydrolase PTH2	-	-	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
DYD2_k127_1548723_26	1229909.NSED_05835	5.456e-14	74.0	arCOG08716@1|root,arCOG10358@1|root,arCOG08716@2157|Archaea,arCOG10358@2157|Archaea,41SYI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1548723_13	436308.Nmar_0451	1.117e-98	325.0	arCOG07871@1|root,arCOG07871@2157|Archaea,41T28@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1061 DNA or RNA helicases of superfamily II	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1548723_12	436308.Nmar_0450	2.934e-103	338.0	COG1676@1|root,arCOG01701@2157|Archaea,41SJY@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
DYD2_k127_1548723_14	1229909.NSED_02325	3.805e-78	265.0	COG0197@1|root,arCOG04113@2157|Archaea,41SKN@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
DYD2_k127_1548723_25	1131266.ARWQ01000010_gene42	1.997e-15	78.0	arCOG10525@1|root,arCOG10525@2157|Archaea,41SUR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1548723_20	1131266.ARWQ01000010_gene43	5.834e-42	158.0	arCOG08731@1|root,arCOG08731@2157|Archaea,41STT@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1548723_2	1229909.NSED_02310	1.14e-200	632.0	COG0475@1|root,arCOG01955@2157|Archaea,41SG1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
DYD2_k127_1548723_1	436308.Nmar_0445	9.71e-229	717.0	COG1196@1|root,arCOG00371@2157|Archaea,41T1Y@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Required for chromosome condensation and partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1548723_0	436308.Nmar_0444	0.0	1081.0	COG1215@1|root,arCOG01389@2157|Archaea,41SDD@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
DYD2_k127_1548723_3	436308.Nmar_0443	3.57e-184	578.0	COG1146@1|root,arCOG04548@2157|Archaea,41SH5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
DYD2_k127_1548723_18	1229909.NSED_02290	2.639e-50	180.0	arCOG08760@1|root,arCOG08760@2157|Archaea,41T7P@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1548723_4	1229909.NSED_02285	2.531e-177	557.0	COG2897@1|root,arCOG02019@2157|Archaea,41SZQ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
DYD2_k127_1548723_6	436308.Nmar_0440	2.303e-148	472.0	COG0061@1|root,arCOG01348@2157|Archaea,41SHP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DYD2_k127_1548723_22	439481.Aboo_0130	1.074e-20	98.0	COG1439@1|root,arCOG00721@2157|Archaea,2XWH2@28890|Euryarchaeota,3F2SW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	PIN domain of ribonuclease	nob1	GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0030490,GO:0030684,GO:0030688,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1990904	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
DYD2_k127_1548723_17	1459636.NTE_01349	1.286e-52	194.0	COG2897@1|root,arCOG02019@2157|Archaea	2157|Archaea	P	COG2897 Rhodanese-related sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
DYD2_k127_1548723_9	436308.Nmar_0437	1.695e-126	407.0	COG1948@1|root,arCOG04206@2157|Archaea,41SIH@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ERCC4 domain	-	-	-	ko:K10848	ko03420,ko03460,map03420,map03460	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	ERCC4,HHH_5
DYD2_k127_1548723_19	436308.Nmar_0436	7.143e-48	175.0	COG1382@1|root,arCOG01342@2157|Archaea,41SPD@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
DYD2_k127_1548723_21	1229909.NSED_02255	1.575e-33	130.0	COG1997@1|root,arCOG04208@2157|Archaea,41SUE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal L37ae protein family	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
DYD2_k127_1548723_5	436308.Nmar_0433	5.952e-149	473.0	COG2123@1|root,arCOG01574@2157|Archaea,41SFZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	-	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
DYD2_k127_1548723_7	1229909.NSED_02245	3.877e-144	458.0	COG0689@1|root,arCOG01575@2157|Archaea,41S81@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	-	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
DYD2_k127_1548723_8	1229909.NSED_02240	3.191e-130	417.0	COG1097@1|root,arCOG00678@2157|Archaea,41SHV@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	-	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	KH_1
DYD2_k127_1548723_10	436308.Nmar_0430	1.481e-121	392.0	COG1500@1|root,arCOG04187@2157|Archaea,41SC7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	-	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
DYD2_k127_1548723_23	436308.Nmar_0936	3.359e-18	89.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1548723_28	1229909.NSED_02870	2.388e-05	49.0	arCOG12097@1|root,arCOG12097@2157|Archaea	1229909.NSED_02870|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1548723_11	436308.Nmar_0428	1.255e-112	365.0	COG0202@1|root,arCOG04241@2157|Archaea,41SK0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase, alpha subunit 40 kD subunit	-	-	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_A_bac,RNA_pol_L
DYD2_k127_1548723_24	1198449.ACAM_1095	4.017e-17	85.0	COG1727@1|root,arCOG00780@2157|Archaea,2XQV1@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the eukaryotic ribosomal protein eL18 family	rpl18e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18,Ribosomal_L27A
DYD2_k127_1548723_16	436308.Nmar_0426	4.189e-62	217.0	COG0102@1|root,arCOG04242@2157|Archaea,41SP4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DYD2_k127_1548723_15	1229909.NSED_02210	8.953e-70	237.0	COG0088@1|root,arCOG04243@2157|Archaea,41SKT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS9 family	-	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DYD2_k127_1578146_1	1229909.NSED_03765	5.028e-64	220.0	arCOG08764@1|root,arCOG08798@2157|Archaea,41SZ3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1578146_0	1229909.NSED_07450	4.884e-226	711.0	COG0475@1|root,arCOG01956@2157|Archaea	2157|Archaea	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Na_H_Exchanger
DYD2_k127_1632653_6	436308.Nmar_0425	2.65e-35	134.0	COG0088@1|root,arCOG04243@2157|Archaea,41SKT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS9 family	-	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DYD2_k127_1632653_2	1229909.NSED_02205	1.887e-122	395.0	COG1208@1|root,arCOG00663@2157|Archaea	2157|Archaea	M	PFAM Nucleotidyl transferase	-	-	2.6.1.37,2.7.7.13	ko:K00966,ko:K03430	ko00051,ko00440,ko00520,ko01100,ko01110,ko01120,map00051,map00440,map00520,map01100,map01110,map01120	M00114,M00361,M00362	R00885,R04152	RC00002,RC00008,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	NTP_transferase
DYD2_k127_1632653_5	649747.HMPREF0083_05837	1.657e-67	234.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,26RMU@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
DYD2_k127_1632653_0	436308.Nmar_0422	1.559e-293	903.0	COG0065@1|root,arCOG01698@2157|Archaea,41SYT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, large subunit	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DYD2_k127_1632653_3	436308.Nmar_0421	3.259e-92	304.0	COG0066@1|root,arCOG02230@2157|Archaea,41SIA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
DYD2_k127_1632653_1	1229909.NSED_02185	5.23e-228	707.0	COG0065@1|root,arCOG01698@2157|Archaea,41S7A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DYD2_k127_1632653_7	436308.Nmar_0420	4.887e-17	81.0	COG0065@1|root,arCOG01698@2157|Archaea,41S7A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
DYD2_k127_1632653_4	1459636.NTE_01896	6.296e-87	292.0	COG2013@1|root,arCOG01907@2157|Archaea,41T1Q@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
DYD2_k127_1635754_3	436308.Nmar_0325	1.711e-08	55.0	COG0099@1|root,arCOG01722@2157|Archaea,41SIW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DYD2_k127_1635754_2	1229909.NSED_01575	1.547e-38	146.0	arCOG08780@1|root,arCOG08780@2157|Archaea,41T84@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1635754_1	436308.Nmar_0327	6.366e-42	159.0	arCOG08779@1|root,arCOG08779@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1635754_0	1229909.NSED_01585	2.239e-172	543.0	COG2132@1|root,arCOG03914@2157|Archaea,41S77@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	PFAM Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
DYD2_k127_1690719_12	1229909.NSED_08835	5.219e-26	107.0	COG1522@1|root,arCOG01117@2157|Archaea	1229909.NSED_08835|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1690719_0	436308.Nmar_1054	2.319e-298	924.0	COG1855@1|root,arCOG04116@2157|Archaea,41SX0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Large family of predicted nucleotide-binding domains	-	-	-	ko:K06865	-	-	-	-	ko00000	-	-	-	KH_1,T2SSE
DYD2_k127_1690719_9	1229909.NSED_06170	5.891e-44	163.0	COG0784@1|root,arCOG02391@2157|Archaea,41TB0@651137|Thaumarchaeota	651137|Thaumarchaeota	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD2_k127_1690719_2	1229909.NSED_06180	1.089e-190	613.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,sCache_3_3
DYD2_k127_1690719_5	436308.Nmar_1056	3.047e-95	314.0	COG1573@1|root,arCOG00905@2157|Archaea,41SJ1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DYD2_k127_1690719_11	517418.Ctha_2648	2.159e-38	150.0	COG2094@1|root,COG2094@2|Bacteria,1FDYR@1090|Chlorobi	1090|Chlorobi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
DYD2_k127_1690719_4	1229909.NSED_06200	1.285e-107	351.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41SMJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DYD2_k127_1690719_8	1229909.NSED_06205	2.288e-60	211.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1690719_13	436308.Nmar_1060	1.663e-24	105.0	arCOG10572@1|root,arCOG10572@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1690719_3	436308.Nmar_1064	3.17e-151	482.0	COG0444@1|root,arCOG00181@2157|Archaea,41S9V@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DYD2_k127_1690719_7	1229909.NSED_05175	6.226e-70	241.0	COG1357@1|root,arCOG03124@2157|Archaea	2157|Archaea	M	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide,Pentapeptide_4
DYD2_k127_1690719_6	436308.Nmar_1065	4.216e-90	299.0	COG0195@1|root,arCOG01761@2157|Archaea,41T4Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1690719_1	1229909.NSED_06225	1.633e-256	793.0	COG0017@1|root,arCOG00406@2157|Archaea,41S93@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2,tRNA_anti-codon
DYD2_k127_1690719_10	1229909.NSED_06230	5.614e-42	154.0	arCOG08788@1|root,arCOG08788@2157|Archaea,41T6K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1744632_1	1229909.NSED_02895	2.4e-51	192.0	COG0517@1|root,arCOG00600@2157|Archaea	2157|Archaea	K	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DYD2_k127_1744632_3	1459636.NTE_01238	3.229e-24	104.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01238|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1744632_2	436308.Nmar_1112	1.179e-37	141.0	arCOG08646@1|root,arCOG08646@2157|Archaea,41T7H@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1744632_0	436308.Nmar_1113	1.996e-180	567.0	COG1236@1|root,arCOG00545@2157|Archaea,41SYB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
DYD2_k127_1770816_3	1229909.NSED_06840	1.56e-23	108.0	COG4263@1|root,arCOG06217@2157|Archaea	2157|Archaea	C	Cytochrome C oxidase, subunit II	nosZ	-	1.7.2.4,1.9.3.1	ko:K00376,ko:K02275	ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120	M00155,M00529	R00081,R02804	RC00016,RC02861	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1,TAT_signal
DYD2_k127_1770816_6	525257.HMPREF0204_11768	2.634e-07	53.0	COG0500@1|root,COG2226@2|Bacteria,4NJ84@976|Bacteroidetes,1HXEK@117743|Flavobacteriia,3ZP0N@59732|Chryseobacterium	976|Bacteroidetes	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DYD2_k127_1770816_1	1229909.NSED_01025	1.338e-33	146.0	COG1340@1|root,arCOG08038@1|root,arCOG01159@2157|Archaea,arCOG08038@2157|Archaea	2157|Archaea	S	protein secretion by the type IV secretion system	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
DYD2_k127_1770816_2	410358.Mlab_0909	2.621e-29	128.0	COG3177@1|root,arCOG03112@2157|Archaea,2Y8I1@28890|Euryarchaeota,2NBD5@224756|Methanomicrobia	224756|Methanomicrobia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
DYD2_k127_1770816_4	436308.Nmar_0613	6.419e-22	95.0	COG0582@1|root,arCOG01241@2157|Archaea	2157|Archaea	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
DYD2_k127_1770816_0	1229909.NSED_02345	2.135e-120	392.0	arCOG08732@1|root,arCOG08732@2157|Archaea,41SR6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1770816_5	1229909.NSED_02350	1.144e-16	79.0	arCOG08742@1|root,arCOG08742@2157|Archaea,41TAD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1778850_6	436308.Nmar_1598	1.386e-49	179.0	arCOG08790@1|root,arCOG08790@2157|Archaea,41SWN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1778850_0	436308.Nmar_1597	6.095e-249	773.0	COG0043@1|root,arCOG01671@2157|Archaea,41SEQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
DYD2_k127_1778850_2	436308.Nmar_1596	7.723e-79	265.0	COG1607@1|root,arCOG00773@2157|Archaea,41T2J@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DYD2_k127_1778850_5	1229909.NSED_08635	9.555e-60	209.0	arCOG10592@1|root,arCOG10594@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1778850_4	436308.Nmar_1592	1.815e-67	231.0	arCOG07348@1|root,arCOG07348@2157|Archaea,41SUQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1778850_7	1229909.NSED_06170	1.561e-26	112.0	COG0784@1|root,arCOG02391@2157|Archaea,41TB0@651137|Thaumarchaeota	651137|Thaumarchaeota	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD2_k127_1778850_3	436308.Nmar_1590	2.316e-72	246.0	arCOG10592@1|root,arCOG10592@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1778850_8	1229909.NSED_00555	2.529e-23	100.0	arCOG10591@1|root,arCOG10591@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1778850_1	436308.Nmar_1588	1.39e-180	567.0	COG0109@1|root,arCOG00479@2157|Archaea,41SFH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DYD2_k127_1782912_2	1229909.NSED_09470	6.611e-95	314.0	COG1814@1|root,arCOG01096@2157|Archaea,41T0M@651137|Thaumarchaeota	651137|Thaumarchaeota	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DYD2_k127_1782912_1	1229909.NSED_09465	1.865e-111	367.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DYD2_k127_1782912_5	436308.Nmar_1768	1.672e-70	241.0	COG0589@1|root,arCOG02053@2157|Archaea,41T7V@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_1782912_9	1229909.NSED_03455	5.13e-58	204.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_1782912_12	760568.Desku_3560	3.149e-46	174.0	COG1926@1|root,COG1926@2|Bacteria,1V256@1239|Firmicutes,249BZ@186801|Clostridia,2623X@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
DYD2_k127_1782912_4	436308.Nmar_0633	6.004e-79	267.0	COG1628@1|root,arCOG00928@2157|Archaea,41SMQ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Protein of unknown function DUF99	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
DYD2_k127_1782912_8	1229909.NSED_06890	2.009e-62	217.0	COG4088@1|root,arCOG01041@2157|Archaea	2157|Archaea	F	PFAM Chromatin associated protein KTI12	pstK	-	2.7.1.164,2.7.1.25	ko:K00860,ko:K10837	ko00230,ko00450,ko00920,ko00970,ko01100,ko01120,map00230,map00450,map00920,map00970,map01100,map01120	M00176	R00509,R04928,R08223	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_33,KTI12
DYD2_k127_1782912_6	1229909.NSED_02125	1.31e-66	236.0	COG0517@1|root,arCOG00601@2157|Archaea	2157|Archaea	C	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1782912_13	1229909.NSED_02905	6.072e-12	68.0	COG1259@1|root,arCOG01759@2157|Archaea	2157|Archaea	S	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
DYD2_k127_1782912_11	1229909.NSED_03470	7.781e-48	175.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	ko:K20989	-	-	-	-	ko00000,ko02000	2.A.21.6	-	-	Usp
DYD2_k127_1782912_10	1229909.NSED_00900	2.076e-56	201.0	COG0071@1|root,arCOG01832@2157|Archaea,41T6B@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DYD2_k127_1782912_14	1229909.NSED_02935	8.702e-05	45.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DYD2_k127_1782912_0	436308.Nmar_1767	9.45e-194	609.0	COG0484@1|root,arCOG02846@2157|Archaea,41T1F@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
DYD2_k127_1782912_3	1229909.NSED_09430	1.852e-88	297.0	arCOG02322@1|root,arCOG07810@1|root,arCOG02322@2157|Archaea,arCOG07810@2157|Archaea,41T0S@651137|Thaumarchaeota	651137|Thaumarchaeota	N	Adenylate guanylate cyclase with integral membrane sensor	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HAMP
DYD2_k127_1821562_3	1229909.NSED_01100	1.442e-53	189.0	COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM 4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
DYD2_k127_1821562_4	1163730.FFONT_1260	1.098e-42	164.0	COG1976@1|root,arCOG04176@2157|Archaea,2XQJ0@28889|Crenarchaeota	28889|Crenarchaeota	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
DYD2_k127_1821562_0	1229909.NSED_01090	7.459e-217	679.0	COG0124@1|root,arCOG00404@2157|Archaea,41S9T@651137|Thaumarchaeota	651137|Thaumarchaeota	J	histidyl-tRNA synthetase	-	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
DYD2_k127_1821562_2	436308.Nmar_0232	6.436e-66	226.0	COG1371@1|root,arCOG04055@2157|Archaea,41SU0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
DYD2_k127_1821562_1	436308.Nmar_0231	5.6e-187	596.0	arCOG06534@1|root,arCOG06534@2157|Archaea	2157|Archaea	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
DYD2_k127_1850317_4	1229909.NSED_08315	1.114e-119	385.0	COG1890@1|root,arCOG04186@2157|Archaea,41SM9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS1 family	rps3ae	-	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
DYD2_k127_1850317_8	1229909.NSED_08320	2.674e-51	185.0	COG1325@1|root,arCOG01042@2157|Archaea,41SWK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA binding	-	-	-	ko:K07581	-	-	-	-	ko00000	-	-	-	RNA_binding
DYD2_k127_1850317_2	1131266.ARWQ01000001_gene1145	1.38e-248	773.0	COG0644@1|root,arCOG00570@2157|Archaea,41SBB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1850317_3	1229909.NSED_08330	6.394e-146	465.0	COG0714@1|root,arCOG00441@2157|Archaea,41SDZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5
DYD2_k127_1850317_0	436308.Nmar_1516	1.282e-278	862.0	COG2304@1|root,arCOG02900@2157|Archaea,41SDY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1850317_1	436308.Nmar_1517	4.744e-260	809.0	COG0031@1|root,arCOG01430@2157|Archaea,41SYY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_1850317_6	1229909.NSED_08345	6.488e-75	253.0	arCOG04405@1|root,arCOG04405@2157|Archaea	2157|Archaea	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
DYD2_k127_1850317_5	436308.Nmar_1519	1.392e-112	364.0	COG2101@1|root,arCOG01764@2157|Archaea,41SZD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	-	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DYD2_k127_1850317_9	436308.Nmar_1520	5.864e-29	116.0	arCOG10588@1|root,arCOG10588@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1850317_7	436308.Nmar_1521	5.591e-56	197.0	arCOG10589@1|root,arCOG10589@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1971527_2	1229909.NSED_05220	7.155e-62	216.0	COG0367@1|root,arCOG00071@2157|Archaea,41SMA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
DYD2_k127_1971527_4	1229909.NSED_05225	4.611e-19	87.0	arCOG04508@1|root,arCOG04508@2157|Archaea,41SVW@651137|Thaumarchaeota	651137|Thaumarchaeota	P	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
DYD2_k127_1971527_3	1229909.NSED_05235	3.475e-61	212.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1971527_0	436308.Nmar_0937	1.034e-188	594.0	COG0667@1|root,arCOG01623@2157|Archaea,41SA6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DYD2_k127_1971527_1	436308.Nmar_0938	2.918e-79	268.0	COG1575@1|root,arCOG00480@2157|Archaea,41S8H@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DYD2_k127_1979000_15	1229909.NSED_09730	1.273e-34	132.0	arCOG08662@1|root,arCOG08662@2157|Archaea	1229909.NSED_09730|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_14	1229909.NSED_03775	8.877e-40	148.0	arCOG08799@1|root,arCOG08799@2157|Archaea,41T6M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_20	436308.Nmar_0733	3.84e-24	101.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41TA2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_17	1229909.NSED_03785	1.154e-29	123.0	arCOG08800@1|root,arCOG08800@2157|Archaea	2157|Archaea	L	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Polysacc_deac_1
DYD2_k127_1979000_3	1229909.NSED_03795	6.774e-231	720.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_13	436308.Nmar_0736	2.047e-40	154.0	arCOG08802@1|root,arCOG08802@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_11	436308.Nmar_0737	2.337e-57	205.0	COG0484@1|root,arCOG02846@2157|Archaea,41T68@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
DYD2_k127_1979000_8	436308.Nmar_0738	2.378e-71	243.0	COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
DYD2_k127_1979000_19	436308.Nmar_0739	1.658e-27	113.0	COG0457@1|root,arCOG03032@2157|Archaea,41T66@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1
DYD2_k127_1979000_6	436308.Nmar_0020	2.597e-154	492.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DYD2_k127_1979000_9	1229909.NSED_04030	2.697e-64	224.0	arCOG03048@1|root,arCOG03048@2157|Archaea,41T7I@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
DYD2_k127_1979000_4	1229909.NSED_04040	1.169e-209	654.0	COG1060@1|root,arCOG00656@2157|Archaea,41SEG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DYD2_k127_1979000_16	1229909.NSED_04045	6.347e-34	133.0	COG0011@1|root,arCOG04373@2157|Archaea,41T99@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
DYD2_k127_1979000_21	1131266.ARWQ01000002_gene611	7.812e-21	94.0	arCOG10538@1|root,arCOG10538@2157|Archaea,41T9G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_1	436308.Nmar_0764	1.909e-275	859.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
DYD2_k127_1979000_23	436308.Nmar_1364	1.613e-05	51.0	arCOG11049@1|root,arCOG11049@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_24	1227484.C471_00910	4.708e-05	49.0	COG3205@1|root,arCOG08188@2157|Archaea,2XZXF@28890|Euryarchaeota,23XIS@183963|Halobacteria	183963|Halobacteria	S	Predicted membrane protein (DUF2061)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
DYD2_k127_1979000_2	436308.Nmar_0865	1.763e-246	766.0	COG0436@1|root,arCOG01130@2157|Archaea	2157|Archaea	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DYD2_k127_1979000_12	436308.Nmar_0745	3.236e-41	153.0	arCOG10539@1|root,arCOG10539@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_5	436308.Nmar_0746	8.036e-160	505.0	COG2107@1|root,arCOG00654@2157|Archaea,41SB8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DYD2_k127_1979000_7	436308.Nmar_0747	1.775e-117	385.0	arCOG00059@1|root,arCOG00059@2157|Archaea,41T4Y@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1979000_0	436308.Nmar_0748	0.0	1321.0	COG0480@1|root,arCOG01559@2157|Archaea,41S9B@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DYD2_k127_2029832_7	1229909.NSED_06335	1.97e-56	198.0	COG0464@1|root,arCOG01307@2157|Archaea,41SA4@651137|Thaumarchaeota	651137|Thaumarchaeota	D	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,MIT,Vps4_C
DYD2_k127_2029832_9	1229909.NSED_06340	1.198e-45	169.0	arCOG08707@1|root,arCOG08707@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2029832_8	436308.Nmar_1090	1.989e-53	193.0	COG5491@1|root,arCOG00452@2157|Archaea	2157|Archaea	N	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
DYD2_k127_2029832_4	436308.Nmar_1091	2.847e-206	646.0	COG1378@1|root,arCOG02037@2157|Archaea,41T17@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DYD2_k127_2029832_6	1229909.NSED_06360	1.454e-69	238.0	COG0251@1|root,arCOG01630@2157|Archaea,41T4N@651137|Thaumarchaeota	651137|Thaumarchaeota	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
DYD2_k127_2029832_5	436308.Nmar_1098	7.847e-189	593.0	COG0608@1|root,arCOG00424@2157|Archaea,41SE2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
DYD2_k127_2029832_2	1229909.NSED_06385	2.627e-224	698.0	COG0372@1|root,arCOG04237@2157|Archaea,41SAN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM 2-methylcitrate synthase citrate synthase II	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DYD2_k127_2029832_11	436308.Nmar_1100	4.61e-36	136.0	arCOG08706@1|root,arCOG08706@2157|Archaea,41SUP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2029832_10	436308.Nmar_1101	8.76e-37	142.0	arCOG10574@1|root,arCOG10574@2157|Archaea,41T8I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2029832_3	1229909.NSED_06400	6.165e-211	661.0	COG3794@1|root,arCOG08764@1|root,arCOG02926@2157|Archaea,arCOG08764@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD2_k127_2029832_1	436308.Nmar_1103	1.04e-284	880.0	COG0322@1|root,arCOG04753@2157|Archaea,41SX9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TIGRFAM excinuclease ABC, C subunit	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
DYD2_k127_2029832_0	1229909.NSED_06410	0.0	1403.0	COG0178@1|root,arCOG04694@2157|Archaea,41T01@651137|Thaumarchaeota	651137|Thaumarchaeota	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DYD2_k127_21675_13	1229909.NSED_01455	1.179e-13	70.0	COG0176@1|root,arCOG05061@2157|Archaea,41S99@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DYD2_k127_21675_5	1229909.NSED_01450	5.281e-187	587.0	COG3958@1|root,arCOG01051@2157|Archaea,41SEP@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
DYD2_k127_21675_1	436308.Nmar_0299	0.0	1005.0	COG0036@1|root,COG3959@1|root,arCOG01053@2157|Archaea,arCOG05046@2157|Archaea,41SBE@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim,Transketolase_N
DYD2_k127_21675_10	1229909.NSED_01435	1.205e-39	150.0	arCOG08747@1|root,arCOG08747@2157|Archaea,41T48@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_21675_2	1229909.NSED_01430	4.033e-252	784.0	COG0260@1|root,arCOG04322@2157|Archaea,41SYD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
DYD2_k127_21675_0	436308.Nmar_0295	0.0	1080.0	COG1245@1|root,arCOG00187@2157|Archaea,41S8K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
DYD2_k127_21675_6	436308.Nmar_0294	7.007e-144	460.0	COG2520@1|root,arCOG00033@2157|Archaea,41S7P@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Met-10+ like-protein	-	-	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
DYD2_k127_21675_11	1229909.NSED_01415	9.568e-35	133.0	COG5625@1|root,arCOG04189@2157|Archaea,41T7F@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HTH DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_21675_8	436308.Nmar_0292	5.807e-98	321.0	COG0456@1|root,arCOG00833@2157|Archaea,41SIY@651137|Thaumarchaeota	651137|Thaumarchaeota	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
DYD2_k127_21675_3	1229909.NSED_01405	7.327e-196	615.0	COG0750@1|root,arCOG00609@2157|Archaea,41S8V@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
DYD2_k127_21675_4	1229909.NSED_01400	3.989e-188	592.0	COG3875@1|root,arCOG02046@2157|Archaea,41SK4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_21675_9	436308.Nmar_0289	1.154e-96	319.0	COG0461@1|root,arCOG00029@2157|Archaea,41SJU@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
DYD2_k127_21675_7	436308.Nmar_0288	1.519e-111	363.0	COG5424@1|root,arCOG06031@2157|Archaea,41SJK@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	-
DYD2_k127_220246_1	1229909.NSED_02175	2.548e-100	328.0	arCOG04033@1|root,arCOG04033@2157|Archaea,41SM5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_220246_0	436308.Nmar_0419	4.419e-132	424.0	COG1478@1|root,arCOG02714@2157|Archaea,41SHA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
DYD2_k127_220246_2	374847.Kcr_0629	8.746e-07	52.0	COG2013@1|root,arCOG01907@2157|Archaea	2157|Archaea	S	TIGRFAM TIGR00266 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
DYD2_k127_2268536_5	1229909.NSED_01810	4.252e-97	327.0	COG1808@1|root,arCOG02264@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
DYD2_k127_2268536_8	1229909.NSED_09025	2.85e-29	122.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	2.7.13.3	ko:K07646,ko:K20989	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	2.A.21.6	-	-	DUF4118,GAF_3,KdpD,Usp
DYD2_k127_2268536_7	436308.Nmar_0621	1.508e-40	153.0	COG1645@1|root,arCOG00578@2157|Archaea,41SVN@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)	-	-	-	ko:K07143	-	-	-	-	ko00000	-	-	-	Auto_anti-p27
DYD2_k127_2268536_6	1229909.NSED_03205	9.646e-59	204.0	COG0023@1|root,arCOG04223@2157|Archaea,41SNU@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the SUI1 family	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DYD2_k127_2268536_3	1229909.NSED_03210	5.802e-123	402.0	arCOG08741@1|root,arCOG08741@2157|Archaea,41SWQ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DYD2_k127_2268536_1	1229909.NSED_03215	8.211e-188	588.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DYD2_k127_2268536_4	1229909.NSED_03220	1.724e-103	339.0	COG1920@1|root,arCOG04472@2157|Archaea,41SPV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Guanylyl transferase CofC like	-	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
DYD2_k127_2268536_0	436308.Nmar_0626	1.389e-194	607.0	COG0391@1|root,arCOG04395@2157|Archaea,41SCH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
DYD2_k127_2268536_2	1229909.NSED_03230	1.875e-125	406.0	arCOG08742@1|root,arCOG08742@2157|Archaea,41SS8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2274091_2	1229909.NSED_09200	8.515e-15	75.0	COG0638@1|root,arCOG00970@2157|Archaea,41T1N@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
DYD2_k127_2274091_0	436308.Nmar_1729	3.959e-177	559.0	COG0371@1|root,arCOG00982@2157|Archaea,41T0B@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
DYD2_k127_2274091_1	1229909.NSED_09210	1.56e-140	448.0	COG1047@1|root,arCOG00980@2157|Archaea,41T0T@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
DYD2_k127_2280810_0	1229909.NSED_07745	1.124e-129	418.0	COG1718@1|root,arCOG01180@2157|Archaea,41T2X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Serine threonine protein kinase involved in cell cycle control	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
DYD2_k127_2280810_2	436308.Nmar_1411	1.072e-34	134.0	COG2412@1|root,arCOG04051@2157|Archaea,41SS6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
DYD2_k127_2280810_1	1229909.NSED_07755	3.663e-84	281.0	COG1601@1|root,arCOG01640@2157|Archaea,41STZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor	-	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	eIF-5_eIF-2B
DYD2_k127_2280810_3	1229909.NSED_07760	9.719e-23	97.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2283319_1	1459636.NTE_03162	3.156e-124	404.0	COG0004@1|root,arCOG04397@2157|Archaea,41SZ0@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
DYD2_k127_2283319_3	1229909.NSED_05495	7.112e-85	284.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T3X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2283319_4	436308.Nmar_0018	1.43e-29	120.0	arCOG08804@1|root,arCOG08804@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2283319_0	436308.Nmar_0019	6.198e-126	410.0	COG1361@1|root,arCOG02079@2157|Archaea	2157|Archaea	M	COG1361 S-layer domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2283319_2	436308.Nmar_0023	2.494e-91	301.0	COG0529@1|root,arCOG01040@2157|Archaea	2157|Archaea	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860,ko:K07028	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_33,APS_kinase
DYD2_k127_2289073_5	1229909.NSED_06255	9.538e-193	604.0	COG0473@1|root,arCOG01163@2157|Archaea,41SAA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DYD2_k127_2289073_2	1229909.NSED_06260	1.358e-305	940.0	COG0119@1|root,arCOG02092@2157|Archaea,41SBX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
DYD2_k127_2289073_8	1229909.NSED_06265	1.34e-87	291.0	COG0440@1|root,arCOG04445@2157|Archaea,41SNS@651137|Thaumarchaeota	651137|Thaumarchaeota	E	acetolactate synthase, small	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
DYD2_k127_2289073_1	1229909.NSED_06270	0.0	1044.0	COG0028@1|root,arCOG01998@2157|Archaea,41S63@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DYD2_k127_2289073_9	436308.Nmar_1077	1.802e-64	222.0	arCOG10267@1|root,arCOG10267@2157|Archaea,41STA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
DYD2_k127_2289073_6	1229909.NSED_06280	4.954e-151	481.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
DYD2_k127_2289073_4	436308.Nmar_1079	9.224e-200	624.0	COG1063@1|root,arCOG01459@2157|Archaea,41S98@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
DYD2_k127_2289073_12	436308.Nmar_1080	1.633e-44	162.0	COG1436@1|root,arCOG04102@2157|Archaea,41T76@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase (F/14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
DYD2_k127_2289073_10	1229909.NSED_06295	4.902e-46	167.0	arCOG08700@1|root,arCOG08700@2157|Archaea,41SV2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2289073_13	436308.Nmar_1082	1.111e-23	103.0	arCOG10573@1|root,arCOG10573@2157|Archaea,41T8W@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2289073_11	436308.Nmar_1083	1.052e-44	163.0	COG5431@1|root,arCOG01120@2157|Archaea,41SW3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2289073_7	1229909.NSED_06310	1.058e-135	434.0	COG1407@1|root,arCOG01150@2157|Archaea,41SJB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
DYD2_k127_2289073_0	436308.Nmar_1085	0.0	1838.0	COG0458@1|root,arCOG01594@2157|Archaea,41SBF@651137|Thaumarchaeota	651137|Thaumarchaeota	E	MGS-like domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DYD2_k127_2289073_3	436308.Nmar_1086	2.21e-213	666.0	COG0505@1|root,arCOG00064@2157|Archaea,41SF0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DYD2_k127_2321952_2	1229909.NSED_02420	9.148e-122	398.0	COG0306@1|root,arCOG02267@2157|Archaea,41SD8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
DYD2_k127_2321952_3	1229909.NSED_02415	2.308e-100	330.0	COG1392@1|root,arCOG02640@2157|Archaea,41SKJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DYD2_k127_2321952_4	1229909.NSED_02410	3.67e-96	334.0	arCOG11445@1|root,arCOG11445@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2321952_1	436308.Nmar_0476	1.827e-148	472.0	COG0842@1|root,arCOG01467@2157|Archaea,41SQQ@651137|Thaumarchaeota	651137|Thaumarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
DYD2_k127_2321952_0	1229909.NSED_02395	2.57e-169	536.0	COG1131@1|root,arCOG00196@2157|Archaea,41S73@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DYD2_k127_2321952_5	436308.Nmar_0474	2.887e-78	263.0	arCOG08735@1|root,arCOG08735@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2324939_0	436308.Nmar_0888	1.414e-262	818.0	COG1199@1|root,arCOG00770@2157|Archaea,41T2V@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_2
DYD2_k127_2324939_1	436308.Nmar_0889	1.599e-43	160.0	arCOG10559@1|root,arCOG10559@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2324939_2	1229909.NSED_05005	4.95e-40	149.0	arCOG10560@1|root,arCOG10560@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2384540_0	436308.Nmar_1182	5.488e-242	753.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
DYD2_k127_2384540_3	1229909.NSED_06615	5.95e-32	125.0	COG1522@1|root,arCOG01117@2157|Archaea,41T6G@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD2_k127_2384540_1	1229909.NSED_07415	2.749e-156	494.0	COG2159@1|root,arCOG01931@2157|Archaea	2157|Archaea	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DYD2_k127_2384540_2	1229909.NSED_07420	1.359e-103	339.0	COG0456@1|root,arCOG00833@2157|Archaea	2157|Archaea	C	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DYD2_k127_2473455_7	1229909.NSED_07100	5.814e-49	175.0	COG0294@1|root,COG1410@1|root,arCOG02029@2157|Archaea,arCOG02817@2157|Archaea,41SXT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
DYD2_k127_2473455_2	436308.Nmar_1268	1.052e-195	612.0	COG0646@1|root,arCOG08715@2157|Archaea,41SWZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
DYD2_k127_2473455_1	436308.Nmar_1269	3.575e-196	616.0	COG0477@1|root,arCOG00130@2157|Archaea	2157|Archaea	EGP	Major facilitator superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,PUCC
DYD2_k127_2473455_5	436308.Nmar_1283	7.105e-117	380.0	COG0600@1|root,arCOG00169@2157|Archaea,41SIT@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
DYD2_k127_2473455_3	436308.Nmar_1284	1.327e-136	437.0	COG1116@1|root,arCOG00193@2157|Archaea,41S6Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
DYD2_k127_2473455_4	1131266.ARWQ01000004_gene1449	3.545e-128	418.0	COG0715@1|root,arCOG01803@2157|Archaea,41SG5@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
DYD2_k127_2473455_0	436308.Nmar_1286	4.125e-239	741.0	COG0137@1|root,arCOG00112@2157|Archaea,41S6K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
DYD2_k127_2473455_8	436308.Nmar_1287	1.764e-27	111.0	arCOG01588@1|root,arCOG01588@2157|Archaea,41SVX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
DYD2_k127_2473455_6	1229909.NSED_07150	7.325e-65	223.0	COG0189@1|root,arCOG01589@2157|Archaea,41SCQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
DYD2_k127_2557761_24	1173264.KI913949_gene2638	0.0004972	46.0	COG1733@1|root,COG1733@2|Bacteria,1G7DW@1117|Cyanobacteria,1HBWZ@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
DYD2_k127_2557761_4	436308.Nmar_0913	1.147e-191	601.0	COG0547@1|root,arCOG02012@2157|Archaea,41SGG@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
DYD2_k127_2557761_13	1131266.ARWQ01000002_gene473	2.588e-79	272.0	COG0134@1|root,arCOG01088@2157|Archaea,41SN7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
DYD2_k127_2557761_2	1229909.NSED_05125	4.562e-235	730.0	COG0133@1|root,arCOG01433@2157|Archaea,41S87@651137|Thaumarchaeota	651137|Thaumarchaeota	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_2557761_15	1120998.AUFC01000002_gene2794	4.035e-54	199.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,3WDB4@538999|Clostridiales incertae sedis	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
DYD2_k127_2557761_19	1229909.NSED_08800	8.791e-36	137.0	arCOG06947@1|root,arCOG06947@2157|Archaea,41TAK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2557761_1	1229909.NSED_05135	0.0	996.0	COG0504@1|root,arCOG00063@2157|Archaea,41S7G@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DYD2_k127_2557761_5	436308.Nmar_0921	3.813e-185	582.0	COG0061@1|root,COG0640@1|root,arCOG00394@2157|Archaea,arCOG01348@2157|Archaea,41SEC@651137|Thaumarchaeota	651137|Thaumarchaeota	HK	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DYD2_k127_2557761_8	1229909.NSED_05150	1.417e-141	453.0	COG0524@1|root,arCOG00016@2157|Archaea,41SJA@651137|Thaumarchaeota	651137|Thaumarchaeota	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DYD2_k127_2557761_16	436308.Nmar_0923	1.855e-50	182.0	COG4830@1|root,arCOG04305@2157|Archaea,41SNM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02976	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S26e
DYD2_k127_2557761_10	1229909.NSED_05160	5.192e-92	306.0	COG0558@1|root,arCOG00670@2157|Archaea,41SJ7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
DYD2_k127_2557761_6	436308.Nmar_0925	8.869e-156	496.0	COG0010@1|root,arCOG01700@2157|Archaea,41T03@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DYD2_k127_2557761_0	1229909.NSED_05170	0.0	1065.0	COG0441@1|root,arCOG00401@2157|Archaea,41S9K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
DYD2_k127_2557761_18	436308.Nmar_0927	1.089e-47	173.0	arCOG08657@1|root,arCOG08657@2157|Archaea,41SRB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2557761_23	1230342.CTM_14813	2.92e-05	51.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,36KH8@31979|Clostridiaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,TusA
DYD2_k127_2557761_3	1229909.NSED_05185	1.412e-210	657.0	COG1899@1|root,arCOG04142@2157|Archaea,41SWS@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
DYD2_k127_2557761_21	436308.Nmar_0929	5.135e-32	125.0	arCOG05330@1|root,arCOG05330@2157|Archaea,41SUC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2557761_17	1229909.NSED_05200	9.81e-50	183.0	COG2164@1|root,arCOG04488@2157|Archaea,41STM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
DYD2_k127_2557761_12	436308.Nmar_0932	1.423e-80	271.0	COG1758@1|root,arCOG01268@2157|Archaea,41ST9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	-	ko:K03014	ko00230,ko00240,ko01100,ko03020,ko04623,ko05016,ko05169,map00230,map00240,map01100,map03020,map04623,map05016,map05169	M00180,M00181,M00182	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
DYD2_k127_2557761_20	436308.Nmar_0933	1.03e-35	138.0	COG1581@1|root,arCOG01753@2157|Archaea,41TA9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Alba	-	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
DYD2_k127_2557761_11	1229909.NSED_05215	2.917e-81	271.0	COG2522@1|root,arCOG00017@2157|Archaea,41SJZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transcriptional regulator	-	-	-	ko:K07108	-	-	-	-	ko00000	-	-	-	-
DYD2_k127_2557761_7	436308.Nmar_0935	5.647e-145	465.0	COG0367@1|root,arCOG00071@2157|Archaea,41SMA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
DYD2_k127_2557761_22	1229909.NSED_05225	2.851e-19	87.0	arCOG04508@1|root,arCOG04508@2157|Archaea,41SVW@651137|Thaumarchaeota	651137|Thaumarchaeota	P	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
DYD2_k127_2557761_14	1229909.NSED_05235	1.229e-60	211.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2557761_9	436308.Nmar_0937	3.326e-137	439.0	COG0667@1|root,arCOG01623@2157|Archaea,41SA6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DYD2_k127_2684372_10	1459636.NTE_00633	2.159e-29	120.0	COG1094@1|root,arCOG04150@2157|Archaea,41SNG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	K homology RNA-binding domain	-	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
DYD2_k127_2684372_0	436308.Nmar_1408	0.0	1075.0	COG1389@1|root,arCOG01165@2157|Archaea,41SJ2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
DYD2_k127_2684372_2	1229909.NSED_07730	3.156e-221	688.0	COG1697@1|root,arCOG04143@2157|Archaea,41SQF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
DYD2_k127_2684372_6	436308.Nmar_1406	6.964e-85	283.0	COG0071@1|root,arCOG01833@2157|Archaea	2157|Archaea	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2684372_11	1229909.NSED_07615	1.947e-21	95.0	arCOG08701@1|root,arCOG08701@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2684372_8	436308.Nmar_1404	1.221e-53	190.0	arCOG08702@1|root,arCOG08702@2157|Archaea,41ST2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2684372_7	1229909.NSED_07605	1.025e-79	266.0	arCOG08703@1|root,arCOG08703@2157|Archaea,41SS0@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2684372_9	1229909.NSED_07600	1.689e-43	159.0	arCOG08704@1|root,arCOG08704@2157|Archaea,41STG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2684372_4	1229909.NSED_07595	1.921e-154	490.0	COG0005@1|root,arCOG01327@2157|Archaea,41SDR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
DYD2_k127_2684372_5	1229909.NSED_07590	8.238e-95	312.0	COG0503@1|root,arCOG00030@2157|Archaea,41SMR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
DYD2_k127_2684372_1	436308.Nmar_1399	8.813e-270	848.0	arCOG08705@1|root,arCOG08705@2157|Archaea,41SXV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2684372_3	436308.Nmar_1398	3.683e-178	560.0	COG3593@1|root,arCOG03235@2157|Archaea,41SZV@651137|Thaumarchaeota	651137|Thaumarchaeota	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
DYD2_k127_2735449_5	1229909.NSED_02905	1.839e-68	234.0	COG1259@1|root,arCOG01759@2157|Archaea	2157|Archaea	S	PFAM Uncharacterised ACR, COG1259	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
DYD2_k127_2735449_8	1229909.NSED_03475	1.057e-25	111.0	COG0589@1|root,arCOG02053@2157|Archaea,41TB2@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_2735449_4	1229909.NSED_09505	3.799e-94	317.0	COG0462@1|root,arCOG00067@2157|Archaea,41SH1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
DYD2_k127_2735449_2	368408.Tpen_0093	1.051e-136	451.0	COG0213@1|root,arCOG02013@2157|Archaea,2XPZT@28889|Crenarchaeota	28889|Crenarchaeota	F	Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO	-	-	2.4.2.57	ko:K18931	-	-	R10836,R10837,R10838	RC00063	ko00000,ko01000	-	-	-	CDC48_N,Glycos_trans_3N,Glycos_transf_3,PYNP_C
DYD2_k127_2735449_9	436308.Nmar_0674	1.865e-20	96.0	COG0589@1|root,arCOG02053@2157|Archaea,41TB2@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_2735449_0	1459636.NTE_01192	1.308e-227	716.0	COG0459@1|root,arCOG01257@2157|Archaea,41SDG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM TCP-1 cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
DYD2_k127_2735449_7	1229909.NSED_02475	6.178e-60	210.0	COG3174@1|root,arCOG04203@2157|Archaea	2157|Archaea	S	membrane	mgtC1	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	DUF4010,MgtC
DYD2_k127_2735449_6	1229909.NSED_00880	6.415e-65	229.0	COG2518@1|root,arCOG00976@2157|Archaea	2157|Archaea	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DYD2_k127_2735449_3	515635.Dtur_0921	4.691e-118	391.0	COG1812@1|root,COG1812@2|Bacteria	2|Bacteria	E	S-adenosylmethionine synthetase (AdoMet synthetase)	metK-2	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
DYD2_k127_2735449_1	1229909.NSED_00895	5.563e-180	568.0	COG1180@1|root,arCOG00946@2157|Archaea,41SBZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
DYD2_k127_2814602_3	436308.Nmar_0319	2.823e-95	316.0	COG2178@1|root,arCOG04318@2157|Archaea,41SKR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translin family	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
DYD2_k127_2814602_7	648757.Rvan_1555	0.0003182	51.0	COG5549@1|root,COG5549@2|Bacteria,1RIJW@1224|Proteobacteria,2UAH9@28211|Alphaproteobacteria,3N8UV@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
DYD2_k127_2814602_1	436308.Nmar_0320	4.092e-116	377.0	COG0063@1|root,arCOG00018@2157|Archaea,41SHM@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	nnrE	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
DYD2_k127_2814602_2	436308.Nmar_0321	2.023e-107	351.0	arCOG00517@1|root,arCOG00517@2157|Archaea,41SHJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DYD2_k127_2814602_5	1459636.NTE_01557	9.7e-88	301.0	COG2038@1|root,arCOG04272@2157|Archaea,41SD3@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the UPF0284 family	-	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
DYD2_k127_2814602_0	1229909.NSED_01560	5e-324	997.0	COG0449@1|root,arCOG00057@2157|Archaea,41SFG@651137|Thaumarchaeota	651137|Thaumarchaeota	M	TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DYD2_k127_2814602_4	1229909.NSED_01565	1.649e-90	301.0	COG0522@1|root,arCOG04239@2157|Archaea,41SN3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S4
DYD2_k127_2814602_6	436308.Nmar_0325	3.04e-78	265.0	COG0099@1|root,arCOG01722@2157|Archaea,41SIW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
DYD2_k127_2830036_3	436308.Nmar_0315	1.468e-28	115.0	COG1577@1|root,arCOG01028@2157|Archaea,41SKC@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
DYD2_k127_2830036_1	1229909.NSED_01515	3.09e-134	430.0	COG1608@1|root,arCOG00860@2157|Archaea,41SI4@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Amino acid kinase family	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DYD2_k127_2830036_2	1131266.ARWQ01000001_gene1190	3.368e-88	296.0	COG1443@1|root,arCOG01081@2157|Archaea,41T09@651137|Thaumarchaeota	651137|Thaumarchaeota	I	NUDIX domain	-	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
DYD2_k127_2830036_0	436308.Nmar_0312	1.317e-170	539.0	COG0142@1|root,arCOG01726@2157|Archaea,41SEV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DYD2_k127_2830036_4	436308.Nmar_1040	1.916e-09	66.0	COG3794@1|root,arCOG05978@1|root,arCOG02926@2157|Archaea,arCOG05978@2157|Archaea	2157|Archaea	C	Fibronectin type III domain protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	Copper-bind,GSDH,ThuA,fn3
DYD2_k127_2830348_1	1229909.NSED_05845	1.914e-120	389.0	COG0672@1|root,arCOG04330@2157|Archaea,41T07@651137|Thaumarchaeota	651137|Thaumarchaeota	P	High-affinity Fe2 Pb2 permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
DYD2_k127_2830348_0	1229909.NSED_05840	0.0	1034.0	COG0145@1|root,arCOG01511@2157|Archaea,41SZ7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
DYD2_k127_2830348_2	1229909.NSED_01660	2.117e-08	61.0	arCOG08643@1|root,arCOG08716@1|root,arCOG08643@2157|Archaea,arCOG08716@2157|Archaea,41T3H@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2847836_3	436308.Nmar_0111	1.667e-53	189.0	COG0432@1|root,arCOG04214@2157|Archaea,41T31@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DYD2_k127_2847836_1	1229909.NSED_00250	6.044e-72	244.0	arCOG08723@1|root,arCOG08723@2157|Archaea,41SPX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2847836_0	436308.Nmar_0109	4.222e-185	582.0	COG1537@1|root,arCOG01741@2157|Archaea,41S6V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	-	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_3
DYD2_k127_2847836_4	436308.Nmar_0108	4.81e-41	153.0	COG1324@1|root,arCOG04231@2157|Archaea,41SR4@651137|Thaumarchaeota	651137|Thaumarchaeota	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
DYD2_k127_2847836_2	436308.Nmar_0107	1.119e-63	220.0	COG0750@1|root,arCOG04064@2157|Archaea,41SW5@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
DYD2_k127_2849474_0	1229909.NSED_05490	0.0	1262.0	COG0308@1|root,arCOG02969@2157|Archaea,41SJH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256,ko:K13722	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
DYD2_k127_2854427_12	1229909.NSED_09675	8.274e-23	97.0	COG1252@1|root,arCOG01067@2157|Archaea	2157|Archaea	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_2854427_1	1229909.NSED_09670	3.117e-192	612.0	COG0652@1|root,arCOG04767@2157|Archaea,41T0W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DYD2_k127_2854427_6	1229909.NSED_09665	9.431e-83	277.0	arCOG08807@1|root,arCOG08807@2157|Archaea,41SRC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2854427_2	1229909.NSED_09660	2.414e-132	424.0	COG2241@1|root,arCOG00650@2157|Archaea,41SGN@651137|Thaumarchaeota	651137|Thaumarchaeota	H	TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit	-	-	2.1.1.289	ko:K03399	ko00860,ko01100,map00860,map01100	-	R05813,R07775	RC00003,RC02052,RC02053	ko00000,ko00001,ko01000	-	-	-	TP_methylase
DYD2_k127_2854427_4	436308.Nmar_0004	6.285e-93	313.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
DYD2_k127_2854427_8	436308.Nmar_0003	3.928e-70	243.0	arCOG01995@1|root,arCOG01995@2157|Archaea,41T3M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
DYD2_k127_2854427_0	436308.Nmar_0002	7.292e-273	843.0	COG1311@1|root,arCOG04455@2157|Archaea,41T0D@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	-	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B
DYD2_k127_2854427_5	399550.Smar_0797	2.555e-86	299.0	COG1474@1|root,arCOG00467@2157|Archaea,2XPXH@28889|Crenarchaeota	28889|Crenarchaeota	L	Involved in regulation of DNA replication	cdc6-1	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_16,AAA_22,Cdc6_C
DYD2_k127_2854427_9	1229909.NSED_09635	2.575e-66	227.0	arCOG04038@1|root,arCOG04038@2157|Archaea,41SQU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2854427_11	436308.Nmar_1798	1.054e-24	104.0	arCOG00818@1|root,arCOG00818@2157|Archaea	2157|Archaea	S	AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
DYD2_k127_2854427_7	436308.Nmar_1797	8.076e-76	259.0	arCOG08041@1|root,arCOG08041@2157|Archaea,41SRT@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
DYD2_k127_2854427_10	436308.Nmar_1796	9.375e-57	199.0	arCOG08806@1|root,arCOG08806@2157|Archaea,41SUU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2854427_3	436308.Nmar_1795	2.878e-126	406.0	COG1646@1|root,arCOG01085@2157|Archaea,41SH4@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
DYD2_k127_2857462_0	1229909.NSED_01615	0.0	994.0	COG1032@1|root,arCOG01357@2157|Archaea,41S86@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DYD2_k127_2857462_4	1229909.NSED_01620	8.982e-130	418.0	COG1691@1|root,arCOG02465@2157|Archaea,41SCY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
DYD2_k127_2857462_3	1229909.NSED_01625	5.047e-178	559.0	COG0039@1|root,arCOG00246@2157|Archaea,41S7Z@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DYD2_k127_2857462_2	1229909.NSED_01630	2.192e-187	592.0	COG1641@1|root,arCOG02701@2157|Archaea,41SDC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
DYD2_k127_2857462_5	1131266.ARWQ01000001_gene1169	5.637e-105	346.0	COG1606@1|root,arCOG00043@2157|Archaea,41SF3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	tRNA methyl transferase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	QueC
DYD2_k127_2857462_1	1229909.NSED_01640	1.219e-191	603.0	COG1104@1|root,arCOG00066@2157|Archaea,41SB1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DYD2_k127_2857462_6	1229909.NSED_01645	1.917e-84	290.0	arCOG08033@1|root,arCOG08643@1|root,arCOG08033@2157|Archaea,arCOG08643@2157|Archaea,41T3A@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2857462_7	436308.Nmar_0345	6.951e-09	56.0	arCOG08643@1|root,arCOG08716@1|root,arCOG08643@2157|Archaea,arCOG08716@2157|Archaea,41T3H@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2913312_1	436308.Nmar_1391	1.864e-200	632.0	COG1498@1|root,arCOG01923@2157|Archaea,41SY9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	NOSIC (NUC001) domain	-	-	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
DYD2_k127_2913312_3	436308.Nmar_1392	3.822e-116	381.0	COG0513@1|root,arCOG00078@2157|Archaea,41SM2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	-	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
DYD2_k127_2913312_5	436308.Nmar_1393	4.602e-102	335.0	COG0164@1|root,arCOG04121@2157|Archaea,41SK9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DYD2_k127_2913312_2	436308.Nmar_1394	1.017e-196	618.0	COG1867@1|root,arCOG01219@2157|Archaea,41SAG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family	-	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
DYD2_k127_2913312_4	436308.Nmar_1395	2.226e-112	364.0	COG0293@1|root,arCOG00079@2157|Archaea,41SIK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rlmE	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
DYD2_k127_2913312_6	436308.Nmar_1396	1.433e-81	276.0	COG1522@1|root,arCOG04153@2157|Archaea,41SP6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2913312_7	1229909.NSED_07575	3.577e-47	174.0	arCOG10583@1|root,arCOG10583@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2913312_0	1229909.NSED_07580	5.39e-242	751.0	COG3593@1|root,arCOG03235@2157|Archaea,41SZV@651137|Thaumarchaeota	651137|Thaumarchaeota	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
DYD2_k127_2922048_4	1229909.NSED_02395	1.91e-56	198.0	COG1131@1|root,arCOG00196@2157|Archaea,41S73@651137|Thaumarchaeota	651137|Thaumarchaeota	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DYD2_k127_2922048_3	436308.Nmar_0474	6.784e-77	259.0	arCOG08735@1|root,arCOG08735@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2922048_6	1131266.ARWQ01000010_gene25	5.637e-24	104.0	arCOG07802@1|root,arCOG07802@2157|Archaea,41T6C@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
DYD2_k127_2922048_0	1229909.NSED_02370	8.5e-113	366.0	arCOG08734@1|root,arCOG08734@2157|Archaea,41SP9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2922048_2	1229909.NSED_02365	1.572e-81	274.0	arCOG10527@1|root,arCOG10527@2157|Archaea,41SPB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2922048_5	1229909.NSED_02360	7.97e-47	170.0	COG0457@1|root,arCOG03032@2157|Archaea,41T5X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
DYD2_k127_2922048_1	1229909.NSED_02355	9.319e-92	305.0	arCOG08733@1|root,arCOG08733@2157|Archaea,41SRN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3162542_3	1229909.NSED_05420	7.741e-11	65.0	COG0574@1|root,arCOG01111@2157|Archaea,41SYV@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Pyruvate phosphate dikinase	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DYD2_k127_3162542_0	436308.Nmar_0952	5.433e-97	319.0	COG3620@1|root,arCOG00608@2157|Archaea,41SJR@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_3
DYD2_k127_3162542_1	1229909.NSED_00340	5.76e-78	270.0	arCOG08796@1|root,arCOG08796@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3162542_2	1229909.NSED_05435	7.013e-74	249.0	COG0346@1|root,arCOG02706@2157|Archaea,41SQS@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
DYD2_k127_3206187_0	436308.Nmar_1488	7.657e-268	833.0	COG0072@1|root,arCOG00412@2157|Archaea,41S8M@651137|Thaumarchaeota	651137|Thaumarchaeota	J	phenylalanyl-tRNA synthetase, beta subunit	-	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5
DYD2_k127_3206187_3	572546.Arcpr_0815	4.069e-92	319.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,245SE@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
DYD2_k127_3206187_1	436308.Nmar_1490	3.869e-225	699.0	COG0180@1|root,arCOG01887@2157|Archaea,41SDK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DYD2_k127_3206187_7	436308.Nmar_1491	8.519e-32	126.0	arCOG10585@1|root,arCOG10585@2157|Archaea,41SW6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3206187_4	436308.Nmar_1492	2.456e-69	243.0	arCOG03272@1|root,arCOG03272@2157|Archaea	436308.Nmar_1492|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3206187_6	1229909.NSED_08215	3.325e-60	209.0	arCOG08641@1|root,arCOG08641@2157|Archaea,41SU7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3206187_5	436308.Nmar_1494	9.913e-63	219.0	COG1986@1|root,arCOG01223@2157|Archaea,41SKV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.3	ko:K02201	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
DYD2_k127_3206187_2	1229909.NSED_08230	9.792e-118	388.0	arCOG08642@1|root,arCOG08642@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_2	118166.JH976537_gene4795	3.169e-115	380.0	COG0596@1|root,COG0596@2|Bacteria,1G0CB@1117|Cyanobacteria,1HAJ3@1150|Oscillatoriales	1117|Cyanobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DYD2_k127_3216939_3	436308.Nmar_0878	6.169e-110	359.0	arCOG06353@1|root,arCOG06353@2157|Archaea,41SI1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
DYD2_k127_3216939_16	436308.Nmar_0879	8.188e-26	107.0	arCOG08746@1|root,arCOG08746@2157|Archaea,41SWA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
DYD2_k127_3216939_18	1131266.ARWQ01000002_gene504	4.095e-17	85.0	COG0640@1|root,arCOG03067@2157|Archaea,41T4C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD2_k127_3216939_22	1459636.NTE_02704	3.672e-10	62.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_12	1229909.NSED_05835	6.836e-37	157.0	arCOG08716@1|root,arCOG10358@1|root,arCOG08716@2157|Archaea,arCOG10358@2157|Archaea,41SYI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_13	1229909.NSED_05860	8.315e-34	132.0	arCOG10582@1|root,arCOG10582@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_9	1229909.NSED_05055	1.69e-54	193.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_17	1229909.NSED_00460	2.197e-24	108.0	COG3161@1|root,arCOG01031@2157|Archaea	2157|Archaea	H	4-hydroxybenzoate synthetase (chorismate lyase)	-	-	2.4.2.54,4.1.3.40	ko:K03181,ko:K06984	ko00130,ko00790,ko01100,ko01110,map00130,map00790,map01100,map01110	M00117	R01302,R10337,R11102	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF98,GHMP_kinases_C,GHMP_kinases_N
DYD2_k127_3216939_8	1229909.NSED_08100	4.924e-58	205.0	COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
DYD2_k127_3216939_5	1229909.NSED_05695	1.213e-70	249.0	COG1405@1|root,arCOG01981@2157|Archaea,41SYU@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DYD2_k127_3216939_11	1229909.NSED_07005	8.411e-42	157.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_6	1229909.NSED_08090	9.766e-69	237.0	COG1522@1|root,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD2_k127_3216939_14	1229909.NSED_08085	3.981e-31	123.0	COG1522@1|root,arCOG01117@2157|Archaea	1229909.NSED_08085|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_7	1229909.NSED_00475	1.641e-64	224.0	arCOG07561@1|root,arCOG07561@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF553,HTH_IclR
DYD2_k127_3216939_1	1229909.NSED_09020	1.034e-137	441.0	arCOG10599@1|root,arCOG10599@2157|Archaea	2157|Archaea	C	copper ion binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_0	1229909.NSED_06790	1.324e-193	606.0	COG1064@1|root,arCOG01455@2157|Archaea,41SK3@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DYD2_k127_3216939_19	1229909.NSED_02925	1.722e-13	70.0	arCOG08648@1|root,arCOG08648@2157|Archaea,41T9C@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3216939_23	8364.ENSXETP00000013246	0.0005736	49.0	KOG2242@1|root,KOG2242@2759|Eukaryota,38FNX@33154|Opisthokonta,3BD0H@33208|Metazoa,3CX5K@33213|Bilateria,47YW2@7711|Chordata,49521@7742|Vertebrata	33208|Metazoa	A	Heterogeneous nuclear ribonucleoprotein U-like protein 2	HNRNPUL2	GO:0000375,GO:0000377,GO:0000398,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0031974,GO:0031981,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:1901360	-	ko:K12888,ko:K15047,ko:K15698	ko03040,ko05164,map03040,map05164	-	-	-	ko00000,ko00001,ko03041,ko04121	-	-	-	AAA_33,SAP,SPRY
DYD2_k127_3216939_10	1229909.NSED_03715	4.414e-42	156.0	arCOG03272@1|root,arCOG03272@2157|Archaea,41T3V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3258642_1	1229909.NSED_09565	5.141e-123	397.0	COG4221@1|root,arCOG01265@2157|Archaea,41S66@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DYD2_k127_3258642_0	1229909.NSED_09560	4.826e-194	610.0	COG0446@1|root,arCOG01064@2157|Archaea,41SZR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_3258642_2	436308.Nmar_1784	4.758e-16	79.0	arCOG08810@1|root,arCOG08810@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3342026_8	1229909.NSED_01930	8.531e-86	287.0	COG0098@1|root,arCOG04087@2157|Archaea,41SFS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS5 family	-	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
DYD2_k127_3342026_11	436308.Nmar_0398	2.486e-82	275.0	COG0256@1|root,arCOG04088@2157|Archaea,41SQW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rpl18	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5e
DYD2_k127_3342026_3	436308.Nmar_0397	4.104e-156	496.0	COG0448@1|root,arCOG00912@2157|Archaea,41SEY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DYD2_k127_3342026_2	1229909.NSED_01910	6.633e-203	640.0	COG0552@1|root,arCOG01227@2157|Archaea,41SCC@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DYD2_k127_3342026_15	1229909.NSED_01905	4.041e-56	198.0	COG1730@1|root,arCOG01341@2157|Archaea,41SSP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdA	-	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
DYD2_k127_3342026_6	1229909.NSED_01900	6.501e-124	398.0	COG0605@1|root,arCOG04147@2157|Archaea,41S6C@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DYD2_k127_3342026_1	436308.Nmar_0393	3.413e-275	862.0	COG1404@1|root,arCOG00702@2157|Archaea,41SX3@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the peptidase S8 family	-	-	-	ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PA,Peptidase_S8
DYD2_k127_3342026_0	1229909.NSED_01890	3.017e-297	917.0	COG1866@1|root,arCOG06073@2157|Archaea,41SE5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
DYD2_k127_3342026_17	1459636.NTE_01388	5.008e-39	150.0	COG1717@1|root,arCOG00781@2157|Archaea,41SP5@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L32e
DYD2_k127_3342026_13	1229909.NSED_01880	8.402e-72	244.0	COG2147@1|root,arCOG04089@2157|Archaea,41SVC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl19e	-	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
DYD2_k127_3342026_16	436308.Nmar_0388	1.977e-47	171.0	COG0350@1|root,arCOG02724@2157|Archaea,41SR8@651137|Thaumarchaeota	651137|Thaumarchaeota	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
DYD2_k127_3342026_5	436308.Nmar_0387	1.115e-128	417.0	COG1650@1|root,arCOG01616@2157|Archaea,41SM3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
DYD2_k127_3342026_10	1229909.NSED_01860	1.45e-84	281.0	COG0250@1|root,arCOG01920@2157|Archaea,41SM6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
DYD2_k127_3342026_12	436308.Nmar_0385	1.503e-76	259.0	COG0080@1|root,arCOG04372@2157|Archaea,41SJW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rpl11	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
DYD2_k127_3342026_14	1229909.NSED_01850	5.971e-70	240.0	COG1522@1|root,arCOG01580@2157|Archaea,41SJD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
DYD2_k127_3342026_9	1131266.ARWQ01000012_gene1619	1.326e-84	286.0	COG0081@1|root,arCOG04289@2157|Archaea,41SHF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
DYD2_k127_3342026_4	1229909.NSED_01840	2.585e-143	458.0	COG0244@1|root,arCOG04288@2157|Archaea,41S9R@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
DYD2_k127_3342026_7	1131266.ARWQ01000001_gene1150	5.049e-95	314.0	COG2860@1|root,arCOG04641@2157|Archaea,41SIS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
DYD2_k127_3472383_0	436308.Nmar_1517	7.631e-200	627.0	COG0031@1|root,arCOG01430@2157|Archaea,41SYY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_3472383_4	1229909.NSED_08345	1.925e-73	249.0	arCOG04405@1|root,arCOG04405@2157|Archaea	2157|Archaea	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
DYD2_k127_3472383_2	436308.Nmar_1519	4.915e-112	362.0	COG2101@1|root,arCOG01764@2157|Archaea,41SZD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	-	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DYD2_k127_3472383_10	436308.Nmar_1520	2.3e-28	115.0	arCOG10588@1|root,arCOG10588@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3472383_3	1229909.NSED_08360	1.733e-100	329.0	arCOG10589@1|root,arCOG10589@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3472383_6	436308.Nmar_1522	1.149e-65	231.0	arCOG08643@1|root,arCOG08643@2157|Archaea,41T5M@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3472383_7	436308.Nmar_1523	2.167e-44	164.0	COG0347@1|root,arCOG02305@2157|Archaea,41TB5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
DYD2_k127_3472383_11	1229909.NSED_04220	1.066e-27	116.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T81@651137|Thaumarchaeota	651137|Thaumarchaeota	S	COG4618 ABC-type protease lipase transport system, ATPase and permease components	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3472383_5	1229909.NSED_08835	4.402e-72	246.0	COG1522@1|root,arCOG01117@2157|Archaea	1229909.NSED_08835|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3472383_8	1229909.NSED_08385	1.7e-37	141.0	COG1522@1|root,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD2_k127_3472383_1	436308.Nmar_1525	6.338e-182	572.0	COG0042@1|root,arCOG00604@2157|Archaea	2157|Archaea	J	Dihydrouridine synthase (Dus)	dusA1	-	-	-	-	-	-	-	-	-	-	-	Dus
DYD2_k127_3472383_9	1229909.NSED_08400	7.653e-30	118.0	arCOG07561@1|root,arCOG07561@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3,VWA
DYD2_k127_350491_2	1229909.NSED_00265	2.165e-60	209.0	COG1321@1|root,arCOG02100@2157|Archaea,41SIJ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress
DYD2_k127_350491_0	1229909.NSED_00270	1.212e-142	454.0	COG1378@1|root,arCOG02038@2157|Archaea,41SFR@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
DYD2_k127_350491_1	436308.Nmar_0115	2.426e-78	263.0	COG1964@1|root,arCOG00933@2157|Archaea,41SAY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Radical SAM	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
DYD2_k127_3511517_22	436308.Nmar_1592	5.589e-14	71.0	arCOG07348@1|root,arCOG07348@2157|Archaea,41SUQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3511517_19	1229909.NSED_06170	8.302e-27	113.0	COG0784@1|root,arCOG02391@2157|Archaea,41TB0@651137|Thaumarchaeota	651137|Thaumarchaeota	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD2_k127_3511517_13	436308.Nmar_1590	7.2e-74	251.0	arCOG10592@1|root,arCOG10592@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3511517_20	436308.Nmar_1589	5.309e-24	102.0	arCOG10591@1|root,arCOG10591@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3511517_4	436308.Nmar_1588	1.014e-180	567.0	COG0109@1|root,arCOG00479@2157|Archaea,41SFH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DYD2_k127_3511517_15	436308.Nmar_1587	1.78e-64	223.0	COG1522@1|root,arCOG01580@2157|Archaea,41SKI@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
DYD2_k127_3511517_3	1229909.NSED_00570	1.182e-194	610.0	COG0136@1|root,arCOG00494@2157|Archaea,41SFD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate-semialdehyde dehydrogenase	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
DYD2_k127_3511517_8	436308.Nmar_1585	1.472e-132	431.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
DYD2_k127_3511517_9	1229909.NSED_00585	1.498e-131	425.0	COG1492@1|root,arCOG00105@2157|Archaea,41SG6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA
DYD2_k127_3511517_7	436308.Nmar_1583	4.986e-146	468.0	COG1270@1|root,arCOG04274@2157|Archaea,41S6I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
DYD2_k127_3511517_16	1459636.NTE_03117	4.308e-53	195.0	COG0368@1|root,arCOG04338@2157|Archaea,41SI6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
DYD2_k127_3511517_12	1229909.NSED_00600	1.071e-77	264.0	COG2266@1|root,arCOG01871@2157|Archaea,41SRI@651137|Thaumarchaeota	651137|Thaumarchaeota	M	MobA-like NTP transferase domain	-	-	2.7.7.62	ko:K19712	ko00860,ko01100,map00860,map01100	-	R05222	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DYD2_k127_3511517_23	384616.Pisl_0434	2.306e-12	68.0	COG2051@1|root,arCOG04108@2157|Archaea,2XR0Y@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM ribosomal protein	rps27e	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
DYD2_k127_3511517_17	436308.Nmar_1579	3.039e-51	182.0	COG1631@1|root,arCOG04109@2157|Archaea,41SQZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl44e	-	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
DYD2_k127_3511517_0	1229909.NSED_00615	3.572e-318	980.0	COG1001@1|root,arCOG00693@2157|Archaea,41SZH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
DYD2_k127_3511517_2	436308.Nmar_1577	3.723e-306	942.0	COG0459@1|root,arCOG01257@2157|Archaea,41T11@651137|Thaumarchaeota	651137|Thaumarchaeota	O	TCP-1/cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
DYD2_k127_3511517_6	436308.Nmar_1576	1.615e-146	468.0	COG1940@1|root,arCOG04280@2157|Archaea,41SWX@651137|Thaumarchaeota	651137|Thaumarchaeota	K	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
DYD2_k127_3511517_21	329726.AM1_3523	4.64e-14	78.0	COG1514@1|root,COG1514@2|Bacteria,1GB04@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Cyclic phosphodiesterase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	CPDase
DYD2_k127_3511517_18	436308.Nmar_1575	1.236e-40	151.0	arCOG08720@1|root,arCOG08720@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF2024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2024
DYD2_k127_3511517_24	767817.Desgi_0878	7.91e-06	55.0	COG3576@1|root,COG3576@2|Bacteria,1VCPZ@1239|Firmicutes,24NTP@186801|Clostridia	186801|Clostridia	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
DYD2_k127_3511517_1	436308.Nmar_1573	4.847e-311	956.0	COG0519@1|root,arCOG00085@2157|Archaea,41SDI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
DYD2_k127_3511517_14	436308.Nmar_1572	1.135e-72	250.0	arCOG05463@1|root,arCOG05463@2157|Archaea,41SR3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3511517_11	1229909.NSED_00650	3.166e-105	346.0	COG1634@1|root,arCOG04303@2157|Archaea,41SKX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP)	mptE	-	2.7.6.3	ko:K07142	ko00790,map00790	-	R03503	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	MAF_flag10
DYD2_k127_3511517_10	1229909.NSED_00655	1.932e-129	419.0	COG0294@1|root,arCOG02817@2157|Archaea,41SGK@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DYD2_k127_3511517_5	1229909.NSED_00660	3.089e-149	475.0	COG0516@1|root,arCOG00612@2157|Archaea,41S7R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
DYD2_k127_3543051_5	1229909.NSED_00400	8.12e-102	333.0	COG2132@1|root,arCOG03914@2157|Archaea,41T22@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind
DYD2_k127_3543051_7	1131266.ARWQ01000003_gene1508	2.309e-63	220.0	COG0109@1|root,arCOG03103@2157|Archaea,41SNT@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
DYD2_k127_3543051_8	436308.Nmar_0187	7.093e-54	194.0	arCOG08825@1|root,arCOG08825@2157|Archaea,41T4G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3543051_4	1229909.NSED_00415	2.473e-119	385.0	COG4276@1|root,arCOG04604@2157|Archaea,41SI9@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DYD2_k127_3543051_9	1229909.NSED_00420	3.986e-36	141.0	COG0784@1|root,arCOG02391@2157|Archaea,41T9J@651137|Thaumarchaeota	2157|Archaea	T	COG0784 FOG CheY-like receiver	-	-	-	ko:K02485,ko:K02490,ko:K03413	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD2_k127_3543051_1	436308.Nmar_0189	1.237e-198	635.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
DYD2_k127_3543051_6	1229909.NSED_00430	1.022e-86	289.0	COG0500@1|root,arCOG04347@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
DYD2_k127_3543051_10	436308.Nmar_0191	6.934e-27	110.0	arCOG08759@1|root,arCOG08759@2157|Archaea,41T9Q@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3543051_2	436308.Nmar_0192	1.4e-175	552.0	COG0115@1|root,arCOG02297@2157|Archaea,41SD5@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DYD2_k127_3543051_11	1229909.NSED_00440	9.367e-22	96.0	arCOG11526@1|root,arCOG11526@2157|Archaea,41T9E@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3543051_0	436308.Nmar_0193	5.012e-237	739.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
DYD2_k127_3543051_3	1229909.NSED_00450	5.216e-152	486.0	COG1819@1|root,arCOG01393@2157|Archaea,41T16@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
DYD2_k127_3543051_12	273057.SSO0138	0.0005809	42.0	arCOG07277@1|root,arCOG07277@2157|Archaea	2157|Archaea	S	ORF D-335-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SSV1_ORF_D-335
DYD2_k127_3561141_3	1229909.NSED_07185	4.412e-163	515.0	COG0189@1|root,arCOG01589@2157|Archaea,41SE8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Lysine biosynthesis	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
DYD2_k127_3561141_1	436308.Nmar_1296	4.815e-211	659.0	COG0624@1|root,arCOG01107@2157|Archaea,41SAX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	M20_dimer,Peptidase_M20
DYD2_k127_3561141_2	436308.Nmar_1297	9.765e-189	593.0	COG1798@1|root,COG1849@1|root,arCOG01224@2157|Archaea,arCOG04161@2157|Archaea,41SC2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	diphthine synthase	-	-	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	-	DUF357,TP_methylase
DYD2_k127_3561141_5	1229909.NSED_07205	1.671e-98	325.0	COG0615@1|root,arCOG01222@2157|Archaea,41SPR@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Cytidylyltransferase-like	-	-	2.7.7.2,2.7.7.39	ko:K00980,ko:K14656	ko00564,ko00740,ko01100,ko01110,map00564,map00740,map01100,map01110	-	R00161,R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DYD2_k127_3561141_4	1229909.NSED_07210	5.391e-119	385.0	COG1339@1|root,arCOG01904@2157|Archaea,41SG9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Domain of unknown function DUF120	-	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase
DYD2_k127_3561141_0	1229909.NSED_07215	2.276e-212	663.0	COG0358@1|root,arCOG04281@2157|Archaea,41S75@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA primase	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
DYD2_k127_3620492_1	436308.Nmar_1179	2.885e-77	262.0	arCOG08686@1|root,arCOG08686@2157|Archaea,41T56@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3620492_0	436308.Nmar_1180	8.834e-104	338.0	COG1945@1|root,arCOG04490@2157|Archaea,41SPZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
DYD2_k127_3662115_1	436308.Nmar_0601	1.713e-158	505.0	COG0024@1|root,arCOG01001@2157|Archaea,41SEA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
DYD2_k127_3662115_2	436308.Nmar_0600	9.435e-23	99.0	arCOG03770@1|root,arCOG03770@2157|Archaea,41TAR@651137|Thaumarchaeota	651137|Thaumarchaeota	M	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3662115_0	436308.Nmar_0599	1.556e-178	565.0	COG4046@1|root,arCOG04181@2157|Archaea,41S8T@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF1512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1512
DYD2_k127_3680634_10	1229909.NSED_04495	6.329e-29	117.0	COG0638@1|root,arCOG00971@2157|Archaea,41SYA@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Proteasome endopeptidase complex	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
DYD2_k127_3680634_1	436308.Nmar_0810	4.548e-142	454.0	COG2106@1|root,arCOG04069@2157|Archaea,41SI7@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative RNA methyltransferase	-	-	-	ko:K09142	-	-	-	-	ko00000	-	-	-	Methyltrn_RNA_3
DYD2_k127_3680634_0	436308.Nmar_0809	7.601e-175	552.0	COG0087@1|root,arCOG04070@2157|Archaea,41SDN@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein L3	-	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
DYD2_k127_3680634_3	436308.Nmar_0808	9.006e-130	419.0	COG0469@1|root,arCOG04071@2157|Archaea,41SHB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein L4	-	-	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
DYD2_k127_3680634_9	436308.Nmar_0807	3.675e-44	162.0	COG0089@1|root,arCOG04072@2157|Archaea,41SS4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome	rpl23	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
DYD2_k127_3680634_6	1229909.NSED_04470	6.658e-70	239.0	COG0185@1|root,arCOG04099@2157|Archaea,41SMH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rps19p	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
DYD2_k127_3680634_4	436308.Nmar_0805	1.067e-85	286.0	COG0091@1|root,arCOG04098@2157|Archaea,41SJ4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rpl22	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
DYD2_k127_3680634_2	436308.Nmar_0804	3.288e-136	436.0	COG0092@1|root,arCOG04097@2157|Archaea,41SIM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds the lower part of the 30S subunit head	rps3	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
DYD2_k127_3680634_12	1229909.NSED_04455	2.538e-28	115.0	COG0255@1|root,arCOG00785@2157|Archaea,41SV8@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uL29 family	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
DYD2_k127_3680634_11	1229909.NSED_04450	7.826e-29	117.0	COG1588@1|root,arCOG00784@2157|Archaea,41TB4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	-	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
DYD2_k127_3680634_8	1229909.NSED_04445	1.546e-53	189.0	COG0186@1|root,arCOG04096@2157|Archaea,41SSH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
DYD2_k127_3680634_5	1229909.NSED_04440	4.426e-77	259.0	COG0093@1|root,arCOG04095@2157|Archaea,41SHG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DYD2_k127_3680634_7	1229909.NSED_04435	5.279e-58	203.0	COG0198@1|root,arCOG04094@2157|Archaea,41SSS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L26
DYD2_k127_3756753_6	436308.Nmar_0789	9.594e-66	228.0	arCOG10550@1|root,arCOG10550@2157|Archaea,41T80@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF4352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
DYD2_k127_3756753_14	1229909.NSED_04370	1.616e-17	85.0	arCOG14547@1|root,arCOG14547@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3756753_5	436308.Nmar_0787	4.986e-66	227.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41SS2@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
DYD2_k127_3756753_4	436308.Nmar_0785	4.466e-75	255.0	COG0640@1|root,arCOG01687@2157|Archaea,41ST3@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD2_k127_3756753_2	436308.Nmar_0784	1.215e-146	467.0	COG0152@1|root,arCOG04421@2157|Archaea,41SAR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DYD2_k127_3756753_9	1229909.NSED_01045	7.15e-52	186.0	arCOG10549@1|root,arCOG10549@2157|Archaea,41STE@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3756753_8	436308.Nmar_0782	2.733e-52	185.0	COG2343@1|root,arCOG06569@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
DYD2_k127_3756753_12	1131266.ARWQ01000002_gene587	1.303e-23	102.0	COG1522@1|root,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD2_k127_3756753_1	436308.Nmar_0781	1.815e-285	879.0	COG0034@1|root,arCOG00093@2157|Archaea,41S7N@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
DYD2_k127_3756753_0	436308.Nmar_0780	0.0	1255.0	COG0046@1|root,arCOG00641@2157|Archaea,41S6S@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DYD2_k127_3756753_3	436308.Nmar_0779	2.047e-130	418.0	COG0047@1|root,arCOG00102@2157|Archaea,41SG3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DYD2_k127_3756753_10	436308.Nmar_0777	5.198e-40	149.0	COG1828@1|root,arCOG04462@2157|Archaea,41STY@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
DYD2_k127_3756753_15	1198449.ACAM_0977	5.704e-15	75.0	COG3369@1|root,arCOG01667@2157|Archaea,2XSEU@28889|Crenarchaeota	28889|Crenarchaeota	S	CDGSH-type zinc finger. Function unknown.	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
DYD2_k127_3756753_13	436308.Nmar_1001	1.292e-19	91.0	COG1522@1|root,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3756753_7	436308.Nmar_1360	3.775e-62	223.0	COG2968@1|root,arCOG04715@2157|Archaea,41T6R@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
DYD2_k127_3756753_11	436308.Nmar_1359	1.31e-38	147.0	COG0640@1|root,arCOG01686@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD2_k127_3792672_1	1229909.NSED_00830	5.919e-155	491.0	COG1042@1|root,arCOG01340@2157|Archaea,41S6N@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18593	ko00720,ko01120,map00720,map01120	-	R10758	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DYD2_k127_3792672_0	436308.Nmar_0207	1.889e-319	979.0	COG2368@1|root,arCOG02143@2157|Archaea,41SA0@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Vinylacetyl-CoA Delta-isomerase	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
DYD2_k127_3792672_3	1229909.NSED_00845	4.789e-93	310.0	COG0681@1|root,arCOG01739@2157|Archaea,41SQ2@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DYD2_k127_3792672_2	1229909.NSED_00850	3.818e-112	366.0	arCOG08023@1|root,arCOG08023@2157|Archaea,41SKK@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
DYD2_k127_3792672_5	436308.Nmar_0210	1.692e-61	212.0	COG0526@1|root,arCOG01972@2157|Archaea,41SSR@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
DYD2_k127_3792672_4	436308.Nmar_0212	3.156e-90	299.0	arCOG08024@1|root,arCOG08024@2157|Archaea,41SRU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
DYD2_k127_3792672_6	436308.Nmar_0211	1.664e-59	207.0	arCOG08025@1|root,arCOG08025@2157|Archaea,41STV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
DYD2_k127_380420_5	436308.Nmar_1263	1.778e-19	88.0	COG2097@1|root,arCOG04473@2157|Archaea,41STQ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the ribosomal protein L31e family	rpl31e	-	-	ko:K02910	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31e
DYD2_k127_380420_4	1229909.NSED_07085	1.112e-22	98.0	COG2167@1|root,arCOG04177@2157|Archaea,41SUT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	-	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
DYD2_k127_380420_1	436308.Nmar_1265	4.365e-79	267.0	COG0494@1|root,arCOG01072@2157|Archaea,41STX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
DYD2_k127_380420_2	1131266.ARWQ01000004_gene1444	5.111e-75	260.0	COG0685@1|root,arCOG00475@2157|Archaea,41SNK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	cytochrome-c peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_380420_0	436308.Nmar_1267	0.0	1492.0	COG0294@1|root,COG1410@1|root,arCOG02029@2157|Archaea,arCOG02817@2157|Archaea,41SXT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
DYD2_k127_380420_3	436308.Nmar_1268	2.547e-73	247.0	COG0646@1|root,arCOG08715@2157|Archaea,41SWZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
DYD2_k127_382786_4	1229909.NSED_01710	4.564e-109	355.0	COG0049@1|root,arCOG04254@2157|Archaea,41S6U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
DYD2_k127_382786_6	436308.Nmar_0354	6.203e-82	273.0	COG0048@1|root,arCOG04255@2157|Archaea,41SIB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
DYD2_k127_382786_5	436308.Nmar_0353	3.956e-88	291.0	COG0195@1|root,arCOG01760@2157|Archaea,41SJQ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
DYD2_k127_382786_7	436308.Nmar_0352	1.065e-48	175.0	COG1911@1|root,arCOG01752@2157|Archaea,41SW9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PFAM ribosomal protein L7Ae L30e S12e Gadd45	-	-	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
DYD2_k127_382786_3	1229909.NSED_01690	5.934e-128	425.0	COG0457@1|root,arCOG08643@1|root,arCOG03032@2157|Archaea,arCOG08643@2157|Archaea	2157|Archaea	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_8
DYD2_k127_382786_2	1229909.NSED_01685	2.759e-156	501.0	arCOG08777@1|root,arCOG08800@1|root,arCOG08777@2157|Archaea,arCOG08800@2157|Archaea	2157|Archaea	L	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Polysacc_deac_1
DYD2_k127_382786_9	436308.Nmar_0349	6.329e-29	117.0	COG1958@1|root,arCOG00998@2157|Archaea	2157|Archaea	K	Like-Sm ribonucleoprotein core	lsm	GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
DYD2_k127_382786_0	436308.Nmar_0348	0.0	2323.0	COG0086@1|root,arCOG04256@2157|Archaea,arCOG04257@2157|Archaea,41SB2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DYD2_k127_382786_1	1229909.NSED_01670	0.0	2192.0	COG0085@1|root,arCOG01762@2157|Archaea,41SF5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DYD2_k127_382786_8	1229909.NSED_01665	7.421e-48	171.0	COG2012@1|root,arCOG04258@2157|Archaea,41SU8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoH	-	2.7.7.6	ko:K03053	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb5_C
DYD2_k127_4058358_7	436308.Nmar_1653	2.314e-05	47.0	COG1108@1|root,arCOG01006@2157|Archaea,41SG2@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
DYD2_k127_4058358_2	1229909.NSED_08955	5.513e-135	432.0	COG1121@1|root,arCOG00201@2157|Archaea,41S7E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
DYD2_k127_4058358_6	1459636.NTE_00032	4.452e-63	227.0	COG0803@1|root,arCOG01005@2157|Archaea,41T29@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
DYD2_k127_4058358_5	1229909.NSED_08965	8.247e-67	228.0	COG0864@1|root,arCOG01008@2157|Archaea,41SQM@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
DYD2_k127_4058358_0	1229909.NSED_08970	3.77e-204	644.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41T50@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4058358_3	1229909.NSED_08975	7.914e-125	404.0	arCOG10598@1|root,arCOG10598@2157|Archaea	2157|Archaea	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
DYD2_k127_4058358_1	436308.Nmar_1686	8.88e-174	548.0	COG0540@1|root,arCOG00911@2157|Archaea,41S6H@651137|Thaumarchaeota	651137|Thaumarchaeota	F	aspartate carbamoyltransferase	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DYD2_k127_4058358_4	436308.Nmar_1687	9.426e-88	291.0	COG1781@1|root,arCOG04229@2157|Archaea,41SJT@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
DYD2_k127_4073800_7	1229909.NSED_04145	5.31e-32	128.0	arCOG08754@1|root,arCOG08754@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4073800_6	436308.Nmar_0505	2.884e-48	174.0	COG1599@1|root,arCOG01510@2157|Archaea,41SV1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
DYD2_k127_4073800_4	436308.Nmar_0504	1.246e-65	230.0	arCOG08762@1|root,arCOG08762@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4073800_5	436308.Nmar_0503	5.532e-63	226.0	arCOG12815@1|root,arCOG12815@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4073800_2	436308.Nmar_0501	1.781e-108	354.0	COG0671@1|root,arCOG03056@2157|Archaea,41SQ8@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
DYD2_k127_4073800_1	436308.Nmar_0500	7.554e-229	713.0	COG0126@1|root,arCOG00496@2157|Archaea,41SMB@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
DYD2_k127_4073800_8	1131266.ARWQ01000005_gene813	6.349e-28	116.0	arCOG08758@1|root,arCOG08758@2157|Archaea,41SVS@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4073800_3	1229909.NSED_02500	1.469e-76	258.0	COG0822@1|root,arCOG02077@2157|Archaea,41SPT@651137|Thaumarchaeota	651137|Thaumarchaeota	C	SUF system FeS assembly protein	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DYD2_k127_4073800_0	1229909.NSED_02495	3.358e-245	760.0	COG0520@1|root,arCOG00065@2157|Archaea,41SCV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DYD2_k127_4265050_0	436308.Nmar_0088	1.423e-288	888.0	COG1201@1|root,arCOG00557@2157|Archaea,41S8P@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DYD2_k127_4265050_1	1229909.NSED_00145	6.442e-163	515.0	COG1599@1|root,arCOG01510@2157|Archaea,41S9M@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
DYD2_k127_439269_16	436308.Nmar_0016	6.968e-31	123.0	arCOG10511@1|root,arCOG10511@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_439269_20	204536.SULAZ_0023	5.439e-16	84.0	COG0589@1|root,COG0589@2|Bacteria,2G4D6@200783|Aquificae	200783|Aquificae	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_439269_15	1229909.NSED_08005	1.619e-33	133.0	COG0589@1|root,arCOG02053@2157|Archaea,41TB2@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_439269_5	1229909.NSED_03465	1.56e-89	303.0	COG0517@1|root,arCOG00600@2157|Archaea	2157|Archaea	K	CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
DYD2_k127_439269_21	604354.TSIB_1201	5.58e-07	61.0	COG0517@1|root,arCOG00606@2157|Archaea,2Y0BC@28890|Euryarchaeota,243NY@183968|Thermococci	183968|Thermococci	K	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DYD2_k127_439269_4	1229909.NSED_02950	6.23e-94	314.0	COG1938@1|root,arCOG00347@2157|Archaea	2157|Archaea	S	COG1938 Archaeal enzymes of ATP-grasp superfamily	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
DYD2_k127_439269_13	1229909.NSED_02945	5.09e-40	152.0	COG0071@1|root,arCOG01832@2157|Archaea	2157|Archaea	O	Belongs to the small heat shock protein (HSP20) family	hsp20	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DYD2_k127_439269_11	1229909.NSED_09725	1.926e-41	154.0	arCOG08691@1|root,arCOG08691@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_439269_8	1229909.NSED_09450	2.173e-67	234.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
DYD2_k127_439269_12	436308.Nmar_0587	7.592e-41	153.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2226,P-II
DYD2_k127_439269_0	436308.Nmar_0588	2.471e-229	715.0	COG0004@1|root,arCOG04397@2157|Archaea,41SZ0@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
DYD2_k127_439269_6	1229909.NSED_05495	3.072e-87	292.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T3X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_439269_18	436308.Nmar_0018	3.546e-28	116.0	arCOG08804@1|root,arCOG08804@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_439269_14	453591.Igni_0968	2.81e-38	149.0	COG0529@1|root,arCOG01040@2157|Archaea,2XQ81@28889|Crenarchaeota	28889|Crenarchaeota	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
DYD2_k127_439269_2	1229909.NSED_09760	5.026e-137	439.0	COG0483@1|root,arCOG01349@2157|Archaea,41T8P@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Inositol monophosphatase	-	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
DYD2_k127_439269_17	1229909.NSED_09765	1.363e-29	119.0	arCOG08813@1|root,arCOG08813@2157|Archaea,41T88@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_439269_3	436308.Nmar_0026	8.294e-133	426.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DYD2_k127_439269_10	436308.Nmar_0027	3.943e-45	167.0	arCOG08814@1|root,arCOG08814@2157|Archaea,41T9Z@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_439269_1	1459636.NTE_01473	1.173e-145	466.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DYD2_k127_439269_7	1229909.NSED_09780	8.136e-78	265.0	COG5491@1|root,arCOG00452@2157|Archaea,41SYC@651137|Thaumarchaeota	651137|Thaumarchaeota	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_439269_9	436308.Nmar_0031	1.177e-60	213.0	arCOG10512@1|root,arCOG10512@2157|Archaea,41T3J@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_439269_19	1131266.ARWQ01000001_gene1337	2.805e-26	109.0	COG3432@1|root,arCOG01055@2157|Archaea,41T3P@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
DYD2_k127_4485413_6	1229909.NSED_03195	2.418e-19	88.0	COG4023@1|root,arCOG02957@2157|Archaea,41SUS@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Sec61beta family	-	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
DYD2_k127_4485413_2	436308.Nmar_0620	3.801e-306	945.0	COG3356@1|root,arCOG04351@2157|Archaea,41S7S@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
DYD2_k127_4485413_3	1229909.NSED_03185	1.02e-98	325.0	arCOG03727@1|root,arCOG03727@2157|Archaea,41STD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
DYD2_k127_4485413_1	1229909.NSED_03180	0.0	1159.0	COG3889@1|root,arCOG01672@2157|Archaea,41SA5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DYD2_k127_4485413_4	1229909.NSED_03175	7.466e-85	282.0	COG2042@1|root,arCOG04733@2157|Archaea,41SMC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ribosome biogenesis protein, C-terminal	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
DYD2_k127_4485413_0	1229909.NSED_03170	0.0	1319.0	arCOG08231@1|root,arCOG08231@2157|Archaea,41T6Q@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
DYD2_k127_4485413_5	436308.Nmar_0602	1.395e-27	113.0	arCOG08744@1|root,arCOG08744@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4568648_0	1229909.NSED_04965	3.946e-19	87.0	arCOG10558@1|root,arCOG10558@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4576146_1	436308.Nmar_1627	1.765e-147	468.0	COG0209@1|root,arCOG03713@1|root,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,41SAH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
DYD2_k127_4576146_0	1229909.NSED_08865	2.189e-181	573.0	arCOG08791@1|root,arCOG08791@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4576146_2	1229909.NSED_08860	3.785e-105	345.0	COG1756@1|root,arCOG04122@2157|Archaea,41T2T@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	-	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
DYD2_k127_4577299_4	1229909.NSED_06495	8.664e-116	374.0	COG2406@1|root,arCOG01093@2157|Archaea,41S6X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
DYD2_k127_4577299_8	1229909.NSED_06500	6.336e-56	196.0	arCOG08645@1|root,arCOG08645@2157|Archaea,41STW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4577299_1	1229909.NSED_06505	4.15e-203	636.0	COG0045@1|root,arCOG01337@2157|Archaea,41S5M@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP-grasp domain	-	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DYD2_k127_4577299_2	1229909.NSED_06510	1.67e-175	552.0	COG0074@1|root,arCOG01339@2157|Archaea,41SEU@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
DYD2_k127_4577299_10	1229909.NSED_06515	3.367e-27	110.0	COG1552@1|root,arCOG04049@2157|Archaea,41T87@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL40 family	-	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	-
DYD2_k127_4577299_9	436308.Nmar_1126	3.299e-30	121.0	arCOG10577@1|root,arCOG10577@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4577299_3	1229909.NSED_06540	2.948e-131	423.0	COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DYD2_k127_4577299_5	1229909.NSED_06555	2.275e-107	348.0	COG0221@1|root,arCOG01711@2157|Archaea,41T3F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
DYD2_k127_4577299_0	436308.Nmar_1177	5e-323	996.0	COG1164@1|root,arCOG04758@2157|Archaea,41S7J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
DYD2_k127_4577299_7	436308.Nmar_1178	8.855e-76	258.0	arCOG11736@1|root,arCOG11736@2157|Archaea,41T70@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4577299_6	1229909.NSED_06590	2.612e-93	314.0	arCOG08686@1|root,arCOG08686@2157|Archaea,41T56@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4589042_0	436308.Nmar_0780	1.27e-185	582.0	COG0046@1|root,arCOG00641@2157|Archaea,41S6S@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DYD2_k127_4589042_1	436308.Nmar_0779	2.047e-130	418.0	COG0047@1|root,arCOG00102@2157|Archaea,41SG3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DYD2_k127_4589042_2	436308.Nmar_0777	2.305e-41	153.0	COG1828@1|root,arCOG04462@2157|Archaea,41STY@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
DYD2_k127_4589042_3	1229909.NSED_07370	6.779e-12	67.0	COG1522@1|root,arCOG01117@2157|Archaea	1229909.NSED_07370|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4594804_13	436308.Nmar_0518	1.125e-35	136.0	COG3277@1|root,arCOG02466@2157|Archaea,41SVG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA-binding protein involved in rRNA processing	-	-	-	ko:K07569	-	-	-	-	ko00000,ko03009	-	-	-	Gar1
DYD2_k127_4594804_2	436308.Nmar_0517	1.733e-184	579.0	COG1405@1|root,arCOG01981@2157|Archaea,41S8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	K	factor TFIIB	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DYD2_k127_4594804_5	436308.Nmar_0516	1.204e-153	487.0	COG0396@1|root,arCOG04236@2157|Archaea,41SE1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
DYD2_k127_4594804_15	1229909.NSED_02590	4.335e-28	114.0	COG1872@1|root,arCOG04058@2157|Archaea,41TAX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
DYD2_k127_4594804_6	1229909.NSED_02585	7.763e-120	387.0	COG3253@1|root,arCOG03031@2157|Archaea,41SGX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
DYD2_k127_4594804_9	1131266.ARWQ01000005_gene827	3.637e-70	242.0	COG1715@1|root,arCOG09740@2157|Archaea,41T5F@651137|Thaumarchaeota	651137|Thaumarchaeota	V	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
DYD2_k127_4594804_4	436308.Nmar_0514	1.327e-177	559.0	COG0667@1|root,arCOG01617@2157|Archaea,41S90@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DYD2_k127_4594804_11	1229909.NSED_02575	1.289e-48	175.0	arCOG10528@1|root,arCOG10528@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4594804_1	436308.Nmar_0512	2.573e-191	600.0	COG1522@1|root,arCOG01628@2157|Archaea,41SA2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4594804_10	1131266.ARWQ01000005_gene823	1.783e-55	201.0	COG1648@1|root,arCOG01044@2157|Archaea,41SN9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Siroheme synthase	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
DYD2_k127_4594804_0	1229909.NSED_02560	1.171e-221	693.0	COG0373@1|root,arCOG01036@2157|Archaea,41SDM@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
DYD2_k127_4594804_3	1229909.NSED_02555	3.046e-180	567.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
DYD2_k127_4594804_12	436308.Nmar_0508	3.252e-41	154.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4594804_16	1229909.NSED_05610	7.071e-24	104.0	arCOG08728@1|root,arCOG08728@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4594804_14	1229909.NSED_05650	2.828e-31	124.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB
DYD2_k127_4594804_7	1229909.NSED_02545	2.268e-96	319.0	COG1418@1|root,arCOG01860@2157|Archaea,41T2N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
DYD2_k127_4594804_8	436308.Nmar_0506	7.546e-94	311.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41T0Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4652002_7	436308.Nmar_1121	3.243e-07	53.0	COG2406@1|root,arCOG01093@2157|Archaea,41S6X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
DYD2_k127_4652002_0	436308.Nmar_1120	0.0	1880.0	COG0060@1|root,arCOG00807@2157|Archaea,41SFF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DYD2_k127_4652002_1	436308.Nmar_1119	8.612e-234	727.0	COG0151@1|root,arCOG04415@2157|Archaea,41SB3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DYD2_k127_4652002_4	1131266.ARWQ01000014_gene80	9.527e-48	177.0	COG0212@1|root,arCOG00474@2157|Archaea,41SRZ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	5-formyltetrahydrofolate cyclo-ligase	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
DYD2_k127_4652002_2	436308.Nmar_1117	2.656e-152	485.0	COG2759@1|root,arCOG04538@2157|Archaea,41S6B@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DYD2_k127_4652002_6	436308.Nmar_1116	5.385e-24	104.0	COG3224@1|root,arCOG08661@2157|Archaea,41T7D@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Antibiotic biosynthesis monooxygenase	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
DYD2_k127_4652002_5	436308.Nmar_1115	2.654e-43	160.0	arCOG03008@1|root,arCOG03008@2157|Archaea,41STF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DYD2_k127_4652002_3	436308.Nmar_1114	4.016e-95	314.0	COG0299@1|root,arCOG02825@2157|Archaea,41SH3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosylglycinamide formyltransferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
DYD2_k127_4688805_2	436308.Nmar_0831	7.669e-203	634.0	COG0057@1|root,arCOG00493@2157|Archaea,41SDF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DYD2_k127_4688805_4	436308.Nmar_0832	3.788e-193	610.0	COG1253@1|root,arCOG00626@2157|Archaea,41T1G@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DYD2_k127_4688805_0	1229909.NSED_04595	1.666e-273	843.0	COG0498@1|root,arCOG01434@2157|Archaea,41S5N@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_4688805_21	436308.Nmar_0834	2.806e-34	135.0	arCOG10552@1|root,arCOG10552@2157|Archaea,41T8T@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_20	1229909.NSED_04605	9.439e-37	141.0	arCOG08697@1|root,arCOG08697@2157|Archaea,41SUN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_15	436308.Nmar_0836	2.829e-66	229.0	arCOG03441@1|root,arCOG03441@2157|Archaea,41SPU@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_13	1229909.NSED_04615	7.342e-84	281.0	COG1591@1|root,arCOG00919@2157|Archaea,41SQP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
DYD2_k127_4688805_9	436308.Nmar_0839	1.143e-121	396.0	COG2263@1|root,arCOG00910@2157|Archaea,41S85@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_22	1229909.NSED_04625	4.624e-34	134.0	COG1545@1|root,arCOG01289@2157|Archaea,41SWD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	-
DYD2_k127_4688805_6	1229909.NSED_04630	2.74e-181	573.0	COG0183@1|root,arCOG01278@2157|Archaea,41SB7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD2_k127_4688805_7	1229909.NSED_04635	4.062e-154	492.0	COG2141@1|root,arCOG02410@2157|Archaea,41SC0@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
DYD2_k127_4688805_11	436308.Nmar_0843	1.301e-107	352.0	COG1208@1|root,arCOG00663@2157|Archaea,41SIU@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
DYD2_k127_4688805_17	1131266.ARWQ01000002_gene614	6.803e-53	191.0	COG0586@1|root,arCOG03117@2157|Archaea,41SQ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DYD2_k127_4688805_24	1229909.NSED_04660	4.649e-23	103.0	arCOG08709@1|root,arCOG08709@2157|Archaea,41T5B@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_5	436308.Nmar_0846	1.176e-187	592.0	COG0026@1|root,arCOG01597@2157|Archaea,41SD9@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
DYD2_k127_4688805_12	436308.Nmar_0847	4.688e-98	323.0	COG0041@1|root,arCOG02464@2157|Archaea,41SN4@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DYD2_k127_4688805_1	1229909.NSED_04675	8.37e-215	672.0	COG1171@1|root,arCOG01431@2157|Archaea,41SCU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_4688805_8	436308.Nmar_0849	1.045e-126	411.0	arCOG08708@1|root,arCOG08708@2157|Archaea,41SPK@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_10	436308.Nmar_0850	2.974e-115	376.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
DYD2_k127_4688805_18	1229909.NSED_04690	2.174e-47	172.0	arCOG10553@1|root,arCOG10553@2157|Archaea,41T8J@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_16	1229909.NSED_04870	2.945e-53	191.0	COG3353@1|root,arCOG01824@2157|Archaea	2157|Archaea	N	Archaeal flagellar protein F	flaF	-	-	ko:K07329	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DYD2_k127_4688805_3	1229909.NSED_04865	4.263e-201	633.0	arCOG03052@1|root,arCOG03871@1|root,arCOG03052@2157|Archaea,arCOG03871@2157|Archaea	2157|Archaea	S	TIGRFAM archaeal flagellin N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_19	436308.Nmar_0852	6.439e-46	170.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T7E@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4688805_14	1229909.NSED_04700	1.769e-71	243.0	COG0346@1|root,arCOG02708@2157|Archaea,41SU3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
DYD2_k127_4688805_23	436308.Nmar_0855	9.456e-32	125.0	arCOG08032@1|root,arCOG08032@2157|Archaea,41T69@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4734595_0	1229909.NSED_08130	7.386e-242	756.0	COG1012@1|root,arCOG01252@2157|Archaea,41T12@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
DYD2_k127_4734595_2	1229909.NSED_08135	2.622e-105	349.0	COG0010@1|root,arCOG01700@2157|Archaea,41T23@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DYD2_k127_4734595_5	1229909.NSED_07470	1.418e-30	125.0	arCOG11327@1|root,arCOG11327@2157|Archaea,41T5V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4734595_3	436308.Nmar_1238	1.306e-41	157.0	COG0457@1|root,arCOG03032@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
DYD2_k127_4734595_1	436308.Nmar_1237	7.24e-137	439.0	COG0157@1|root,arCOG01482@2157|Archaea,41SHI@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Involved in the catabolism of quinolinic acid (QA)	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
DYD2_k127_4734595_4	436308.Nmar_1236	1.221e-32	126.0	COG2093@1|root,arCOG04077@2157|Archaea,41SVE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
DYD2_k127_4734595_6	436308.Nmar_1235	1.951e-29	117.0	COG1095@1|root,arCOG00675@2157|Archaea,41SGF@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase	-	-	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
DYD2_k127_4758995_2	1131266.ARWQ01000001_gene1176	2.783e-06	56.0	arCOG08038@1|root,arCOG08038@2157|Archaea,41SZN@651137|Thaumarchaeota	651137|Thaumarchaeota	S	protein secretion by the type IV secretion system	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4758995_1	436308.Nmar_1778	5.411e-22	104.0	arCOG08685@1|root,arCOG08685@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4758995_0	1229909.NSED_02340	4.011e-54	192.0	COG0454@1|root,arCOG00826@2157|Archaea	2157|Archaea	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD2_k127_4781535_4	1229909.NSED_01265	4.842e-17	81.0	COG0439@1|root,arCOG01590@2157|Archaea,41SXC@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Carbamoyl-phosphate synthase L chain	-	-	6.4.1.2,6.4.1.3	ko:K18603	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DYD2_k127_4781535_2	1229909.NSED_01270	2.821e-75	255.0	COG5016@1|root,arCOG02095@2157|Archaea,41SKA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Biotin-requiring enzyme	-	-	-	ko:K18605	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001	-	-	-	Biotin_lipoyl
DYD2_k127_4781535_1	436308.Nmar_0275	3.569e-83	277.0	COG1225@1|root,arCOG00310@2157|Archaea,41SKG@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DYD2_k127_4781535_3	1131266.ARWQ01000008_gene338	2.831e-60	210.0	COG0838@1|root,arCOG01557@2157|Archaea,41SMI@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
DYD2_k127_4781535_0	1229909.NSED_01285	5.655e-112	361.0	COG0377@1|root,arCOG01554@2157|Archaea,41S6D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the complex I 20 kDa subunit family	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
DYD2_k127_4781535_5	1229909.NSED_01290	5.786e-09	59.0	COG0852@1|root,arCOG01551@2157|Archaea,41SJS@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase 27 kD subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
DYD2_k127_4792395_3	1229909.NSED_08290	5.449e-48	175.0	arCOG10587@1|root,arCOG10587@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4792395_2	1229909.NSED_08295	4.206e-79	265.0	COG0184@1|root,arCOG04185@2157|Archaea,41SKP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	rps15	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
DYD2_k127_4792395_0	1229909.NSED_08300	1.493e-272	842.0	COG0608@1|root,arCOG00427@2157|Archaea,41SZF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
DYD2_k127_4792395_1	1229909.NSED_08310	1.545e-233	726.0	COG0172@1|root,arCOG00403@2157|Archaea,41SC9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DYD2_k127_4830147_1	1229909.NSED_03735	2.069e-68	245.0	arCOG08796@1|root,arCOG08796@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4830147_0	1229909.NSED_03865	2.765e-167	539.0	arCOG08796@1|root,arCOG08796@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4830147_2	1229909.NSED_02340	1.41e-12	68.0	COG0454@1|root,arCOG00826@2157|Archaea	2157|Archaea	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD2_k127_4832166_1	436308.Nmar_0253	2.741e-180	565.0	COG1018@1|root,arCOG02200@2157|Archaea,41S72@651137|Thaumarchaeota	651137|Thaumarchaeota	C	oxidoreductase FAD NAD(P)-binding	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
DYD2_k127_4832166_5	1229909.NSED_01160	1.024e-93	310.0	COG1056@1|root,arCOG00972@2157|Archaea,41SHQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Nicotinamide-nucleotide adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4832166_3	436308.Nmar_0248	4.613e-172	542.0	COG0115@1|root,arCOG02297@2157|Archaea,41S5T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
DYD2_k127_4832166_2	1229909.NSED_01150	6.113e-173	545.0	COG0673@1|root,arCOG01622@2157|Archaea,41SZ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DYD2_k127_4832166_7	436308.Nmar_0246	2.258e-43	159.0	COG2835@1|root,arCOG04124@2157|Archaea,41STB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
DYD2_k127_4832166_6	1229909.NSED_01140	2.105e-88	292.0	COG0110@1|root,arCOG01848@2157|Archaea,41SJ0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DYD2_k127_4832166_8	1229909.NSED_01135	2.057e-26	110.0	arCOG11288@1|root,arCOG11288@2157|Archaea,41T86@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4832166_4	436308.Nmar_0244	7.373e-166	526.0	COG0472@1|root,arCOG03199@2157|Archaea,41S8B@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family	-	-	2.7.8.15	ko:K01001	ko00510,ko01100,map00510,map01100	M00055	R05969	RC00002	ko00000,ko00001,ko00002,ko01000,ko01003	-	-	-	Glycos_transf_4
DYD2_k127_4832166_0	436308.Nmar_0243	0.0	1220.0	COG1204@1|root,arCOG00553@2157|Archaea,41SAK@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
DYD2_k127_4866056_6	1229909.NSED_09560	2.018e-124	402.0	COG0446@1|root,arCOG01064@2157|Archaea,41SZR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_4866056_17	436308.Nmar_1784	8.298e-19	87.0	arCOG08810@1|root,arCOG08810@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4866056_13	1459636.NTE_03047	4.071e-45	173.0	COG2112@1|root,arCOG01182@2157|Archaea,41SJV@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Ser thr protein kinase	-	-	-	ko:K07176	-	-	-	-	ko00000	-	-	-	RIO1
DYD2_k127_4866056_0	436308.Nmar_1782	2.336e-192	609.0	COG1746@1|root,arCOG04249@2157|Archaea,41S76@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
DYD2_k127_4866056_10	436308.Nmar_1781	1.58e-64	228.0	COG1514@1|root,arCOG01736@2157|Archaea,41SP7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DYD2_k127_4866056_8	1229909.NSED_09535	1.33e-84	283.0	COG0237@1|root,arCOG01045@2157|Archaea,41SI8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17
DYD2_k127_4866056_12	436308.Nmar_1779	9.813e-51	183.0	COG1931@1|root,arCOG01043@2157|Archaea,41SRJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0201 family	-	-	-	ko:K09736	-	-	-	-	ko00000	-	-	-	RNA_binding
DYD2_k127_4866056_5	436308.Nmar_1777	1.961e-128	413.0	COG0846@1|root,arCOG04248@2157|Archaea,41SWP@651137|Thaumarchaeota	651137|Thaumarchaeota	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
DYD2_k127_4866056_2	1229909.NSED_09515	2.111e-157	500.0	COG1234@1|root,arCOG00501@2157|Archaea,41SF7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
DYD2_k127_4866056_3	1229909.NSED_09510	1.752e-150	481.0	COG1041@1|root,arCOG00047@2157|Archaea	2157|Archaea	L	RNA methylase	trmG10	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.213	ko:K07446	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP,UPF0020
DYD2_k127_4866056_4	1229909.NSED_09505	2.067e-132	428.0	COG0462@1|root,arCOG00067@2157|Archaea,41SH1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
DYD2_k127_4866056_9	436308.Nmar_1770	3.747e-83	280.0	arCOG08811@1|root,arCOG08811@2157|Archaea,41T85@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4866056_11	1229909.NSED_05445	3.36e-52	188.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8H@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_4866056_15	1123057.P872_13995	1.062e-28	127.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DYD2_k127_4866056_1	436308.Nmar_1769	3.823e-190	601.0	COG0531@1|root,arCOG00009@2157|Archaea,41SXX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DYD2_k127_4866056_16	1229909.NSED_02935	8.063e-24	111.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DYD2_k127_4866056_14	436308.Nmar_1306	1.513e-40	153.0	COG0640@1|root,arCOG03067@2157|Archaea,41TA3@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4866056_7	1229909.NSED_03450	8.154e-120	391.0	COG0039@1|root,arCOG00246@2157|Archaea,41S7Z@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DYD2_k127_4866056_18	1229909.NSED_09470	8.331e-16	78.0	COG1814@1|root,arCOG01096@2157|Archaea,41T0M@651137|Thaumarchaeota	651137|Thaumarchaeota	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
DYD2_k127_4870345_1	436308.Nmar_1047	1.082e-277	879.0	arCOG03561@1|root,arCOG05978@1|root,arCOG06534@1|root,arCOG03561@2157|Archaea,arCOG05978@2157|Archaea,arCOG06534@2157|Archaea	2157|Archaea	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,NHL,Tail_P2_I
DYD2_k127_4870345_7	1459636.NTE_03510	1.29e-98	331.0	COG0861@1|root,arCOG09430@2157|Archaea	2157|Archaea	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
DYD2_k127_4870345_11	1229909.NSED_03620	1.098e-42	157.0	arCOG08659@1|root,arCOG08659@2157|Archaea,41T5K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4870345_0	436308.Nmar_0698	4.914e-296	914.0	COG1351@1|root,arCOG01884@2157|Archaea,41SF6@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
DYD2_k127_4870345_9	436308.Nmar_0697	2.011e-70	239.0	COG0229@1|root,arCOG02815@2157|Archaea,41SMK@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
DYD2_k127_4870345_3	436308.Nmar_0696	6.204e-190	595.0	COG0460@1|root,arCOG01351@2157|Archaea,41SAC@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
DYD2_k127_4870345_8	436308.Nmar_0695	2.905e-79	267.0	COG2016@1|root,arCOG00985@2157|Archaea,41SSC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PUA domain	-	-	-	ko:K07575	-	-	-	-	ko00000	-	-	-	PUA
DYD2_k127_4870345_6	436308.Nmar_0694	1.064e-111	362.0	COG0638@1|root,arCOG00970@2157|Archaea,41SGS@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
DYD2_k127_4870345_10	1229909.NSED_03590	6.348e-44	170.0	COG2259@1|root,arCOG08092@2157|Archaea	2157|Archaea	S	DoxX family	-	-	1.8.5.2	ko:K15977,ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
DYD2_k127_4870345_2	436308.Nmar_0692	2.655e-252	782.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
DYD2_k127_4870345_5	1229909.NSED_03580	1.135e-141	454.0	COG0063@1|root,arCOG00018@2157|Archaea,41S8I@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
DYD2_k127_4870345_4	436308.Nmar_0690	1.392e-151	482.0	COG2519@1|root,arCOG00978@2157|Archaea,41SEF@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
DYD2_k127_4916858_24	1229909.NSED_08145	5.03e-19	89.0	arCOG14181@1|root,arCOG14181@2157|Archaea	1229909.NSED_08145|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_3	1229909.NSED_04150	1.381e-74	255.0	arCOG10540@1|root,arCOG10540@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_19	436308.Nmar_0750	1.74e-27	113.0	arCOG10541@1|root,arCOG10541@2157|Archaea,41T8Z@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_20	436308.Nmar_0751	8.835e-23	100.0	arCOG10542@1|root,arCOG10542@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_8	436308.Nmar_0752	1.364e-54	194.0	arCOG10543@1|root,arCOG10543@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_27	436308.Nmar_0753	2.295e-10	64.0	arCOG10544@1|root,arCOG10544@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_11	1229909.NSED_04180	1.509e-43	169.0	COG3794@1|root,arCOG02926@2157|Archaea,41T8E@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD2_k127_4916858_2	436308.Nmar_0754	9.16e-108	366.0	COG1196@1|root,arCOG00371@2157|Archaea	2157|Archaea	D	Required for chromosome condensation and partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_21	436308.Nmar_1647	9.148e-22	108.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41T0K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_7	436308.Nmar_0756	5.804e-56	198.0	arCOG05565@1|root,arCOG05565@2157|Archaea,41T3I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_14	1229909.NSED_04200	6.963e-36	139.0	arCOG11446@1|root,arCOG11446@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_26	1229909.NSED_04210	1.579e-16	81.0	arCOG11725@1|root,arCOG11725@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_16	1131266.ARWQ01000002_gene601	4.524e-34	132.0	COG1656@1|root,arCOG04290@2157|Archaea,41T6F@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_5	1229909.NSED_04230	1.626e-71	246.0	arCOG11447@1|root,arCOG11447@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_23	1229909.NSED_04235	2.316e-20	93.0	arCOG10545@1|root,arCOG10545@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_12	436308.Nmar_0762	1.247e-39	148.0	arCOG10546@1|root,arCOG10546@2157|Archaea,41SRD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_1	1229909.NSED_04245	4.468e-123	401.0	arCOG08714@1|root,arCOG08714@2157|Archaea,41SPW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_4	436308.Nmar_0765	9.653e-74	250.0	COG1259@1|root,arCOG01759@2157|Archaea,41SQI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
DYD2_k127_4916858_22	436308.Nmar_1648	2.097e-21	106.0	arCOG08793@1|root,arCOG08793@2157|Archaea,41TBC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_18	1229909.NSED_04260	1.942e-28	115.0	arCOG10547@1|root,arCOG10547@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_15	1229909.NSED_04270	1.883e-34	135.0	arCOG08800@1|root,arCOG08800@2157|Archaea	2157|Archaea	L	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Polysacc_deac_1
DYD2_k127_4916858_10	1229909.NSED_01080	3.977e-50	184.0	COG0317@1|root,arCOG06870@2157|Archaea	2157|Archaea	KT	HD domain	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
DYD2_k127_4916858_6	1229909.NSED_05080	7.85e-71	246.0	arCOG11450@1|root,arCOG11450@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_17	1229909.NSED_04275	1.698e-33	130.0	arCOG10548@1|root,arCOG10548@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_13	1229909.NSED_04280	4.352e-36	138.0	arCOG07555@1|root,arCOG07555@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_9	1229909.NSED_05510	3.861e-51	181.0	arCOG10521@1|root,arCOG10521@2157|Archaea,41T8A@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4916858_0	436308.Nmar_0770	2.522e-145	462.0	COG1759@1|root,arCOG04346@2157|Archaea,41S79@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Domain of unknown function (DUF1297)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
DYD2_k127_4946677_35	33898.JRHJ01000023_gene6743	9.93e-09	61.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DYD2_k127_4946677_6	1229909.NSED_03345	1.056e-213	666.0	COG1260@1|root,arCOG04213@2157|Archaea,41SEZ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
DYD2_k127_4946677_0	1229909.NSED_03355	0.0	1716.0	COG1196@1|root,arCOG00371@2157|Archaea,41SDS@651137|Thaumarchaeota	651137|Thaumarchaeota	D	SMC proteins Flexible Hinge Domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DYD2_k127_4946677_14	436308.Nmar_0652	1.652e-159	508.0	COG4608@1|root,arCOG00184@2157|Archaea,41S9E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DYD2_k127_4946677_15	1229909.NSED_03365	7.269e-159	507.0	COG4301@1|root,arCOG06722@2157|Archaea,41SWR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
DYD2_k127_4946677_4	436308.Nmar_0657	2.785e-254	787.0	COG1262@1|root,arCOG03517@2157|Archaea,41T1B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
DYD2_k127_4946677_3	436308.Nmar_0658	2.339e-276	854.0	COG0008@1|root,arCOG00402@2157|Archaea,41SFI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DYD2_k127_4946677_25	436308.Nmar_0659	1.242e-42	157.0	arCOG07440@1|root,arCOG07440@2157|Archaea,41STP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4946677_18	436308.Nmar_0666	6.315e-116	376.0	COG0560@1|root,arCOG01158@2157|Archaea,41SHX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
DYD2_k127_4946677_20	436308.Nmar_0667	5.663e-98	325.0	COG1478@1|root,arCOG02714@2157|Archaea,41T27@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
DYD2_k127_4946677_12	436308.Nmar_0668	4.101e-167	528.0	COG0613@1|root,arCOG00302@2157|Archaea,41S5J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP_C
DYD2_k127_4946677_27	1229909.NSED_03505	5.929e-39	146.0	COG0425@1|root,arCOG02062@2157|Archaea,41SU5@651137|Thaumarchaeota	651137|Thaumarchaeota	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	TusA
DYD2_k127_4946677_8	1229909.NSED_03500	2.321e-198	619.0	COG0031@1|root,arCOG01430@2157|Archaea,41SYM@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine synthase	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_4946677_24	1229909.NSED_03495	5.468e-54	194.0	arCOG10533@1|root,arCOG10533@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4946677_26	1229909.NSED_02430	1.74e-42	157.0	arCOG11286@1|root,arCOG11286@2157|Archaea	2157|Archaea	S	Nitrogen regulatory protein P-II	-	-	-	-	-	-	-	-	-	-	-	-	P-II
DYD2_k127_4946677_11	1229909.NSED_02425	1.946e-173	550.0	COG3329@1|root,arCOG11287@2157|Archaea	2157|Archaea	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
DYD2_k127_4946677_10	436308.Nmar_0672	1.552e-191	600.0	COG0492@1|root,arCOG01296@2157|Archaea,41S97@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_4946677_33	1229909.NSED_06670	4.063e-19	91.0	arCOG08757@1|root,arCOG08757@2157|Archaea	1229909.NSED_06670|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4946677_21	436308.Nmar_0677	1.267e-87	297.0	arCOG04668@1|root,arCOG04668@2157|Archaea,41SMD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4946677_13	1229909.NSED_03435	1.608e-161	510.0	COG1635@1|root,arCOG00574@2157|Archaea,41SDJ@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur	thi4	-	-	ko:K03146	ko00730,ko01100,map00730,map01100	-	R10685	RC00033,RC03253,RC03254	ko00000,ko00001	-	-	-	Thi4
DYD2_k127_4946677_1	1229909.NSED_03430	0.0	1071.0	COG0155@1|root,arCOG02055@2157|Archaea,41S5Q@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Sulfite reductase	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
DYD2_k127_4946677_16	436308.Nmar_0680	7.072e-140	448.0	COG2897@1|root,arCOG02019@2157|Archaea,41SBN@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
DYD2_k127_4946677_9	436308.Nmar_0681	1.624e-193	608.0	COG0457@1|root,arCOG03032@2157|Archaea,41SBD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
DYD2_k127_4946677_5	1229909.NSED_03415	9.943e-232	728.0	arCOG03053@1|root,arCOG03053@2157|Archaea	2157|Archaea	H	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4946677_7	436308.Nmar_0684	3.826e-211	659.0	COG1163@1|root,arCOG00358@2157|Archaea,41SAD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
DYD2_k127_4946677_30	436308.Nmar_0826	1.655e-26	111.0	arCOG10551@1|root,arCOG10551@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4946677_17	1229909.NSED_07460	2.43e-124	404.0	COG0330@1|root,arCOG01915@2157|Archaea,41SYP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DYD2_k127_4946677_31	1229909.NSED_07455	1.66e-24	108.0	COG1846@1|root,arCOG03748@2157|Archaea	2157|Archaea	K	RNA secondary structure unwinding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45,MarR_2,TrmB
DYD2_k127_4946677_32	1229909.NSED_07345	2.656e-20	90.0	arCOG03272@1|root,arCOG03272@2157|Archaea	2157|Archaea	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
DYD2_k127_4946677_19	436308.Nmar_0685	5.358e-103	340.0	COG0561@1|root,arCOG01213@2157|Archaea,41SIV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Phosphoglycolate phosphatase	-	-	3.1.3.18	ko:K22223	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
DYD2_k127_4946677_2	436308.Nmar_0686	0.0	1045.0	COG0018@1|root,arCOG00487@2157|Archaea,41SAI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DYD2_k127_4946677_22	436308.Nmar_0690	1.139e-85	285.0	COG2519@1|root,arCOG00978@2157|Archaea,41SEF@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
DYD2_k127_505105_1	1229909.NSED_09675	6.048e-244	757.0	COG1252@1|root,arCOG01067@2157|Archaea	2157|Archaea	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_505105_3	436308.Nmar_0009	1.198e-109	357.0	arCOG01806@1|root,arCOG01806@2157|Archaea,41T2B@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_505105_4	1229909.NSED_09685	2.518e-82	275.0	COG0071@1|root,arCOG01833@2157|Archaea,41SPJ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DYD2_k127_505105_0	439481.Aboo_0405	3.575e-268	842.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,3F39E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
DYD2_k127_505105_7	1229909.NSED_09695	1.25e-34	133.0	arCOG11529@1|root,arCOG11529@2157|Archaea,41TAA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_505105_2	1229909.NSED_09705	1.777e-164	520.0	COG1405@1|root,arCOG01981@2157|Archaea	2157|Archaea	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DYD2_k127_505105_8	1229909.NSED_09710	1.221e-27	112.0	COG5466@1|root,arCOG05278@2157|Archaea	2157|Archaea	S	small metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
DYD2_k127_505105_5	436308.Nmar_0015	9.365e-62	214.0	COG0239@1|root,arCOG04701@2157|Archaea,41T4U@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
DYD2_k127_505105_6	1229909.NSED_08010	5.721e-61	214.0	COG0517@1|root,arCOG00606@2157|Archaea,41T8N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
DYD2_k127_5121395_4	436308.Nmar_0305	3.227e-55	194.0	arCOG08781@1|root,arCOG08781@2157|Archaea,41SVY@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5121395_7	1229909.NSED_08055	2.674e-32	128.0	arCOG08127@1|root,arCOG08127@2157|Archaea,41T5Y@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5121395_8	1229909.NSED_08060	1.532e-20	98.0	COG0640@1|root,arCOG00731@2157|Archaea,41T59@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
DYD2_k127_5121395_5	436308.Nmar_0408	1.033e-44	170.0	arCOG08670@1|root,arCOG08670@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
DYD2_k127_5121395_3	1229909.NSED_04525	5.001e-106	349.0	COG0785@1|root,arCOG02398@2157|Archaea,41SZE@651137|Thaumarchaeota	651137|Thaumarchaeota	O	cytochrome c biogenesis protein	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
DYD2_k127_5121395_1	1229909.NSED_04520	8.437e-144	464.0	arCOG03562@1|root,arCOG03562@2157|Archaea,41SY7@651137|Thaumarchaeota	651137|Thaumarchaeota	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DYD2_k127_5121395_9	1380347.JNII01000012_gene2662	2.251e-09	59.0	COG5466@1|root,COG5466@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
DYD2_k127_5121395_0	436308.Nmar_0303	2.454e-158	505.0	COG0598@1|root,arCOG02265@2157|Archaea,41SZC@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DYD2_k127_5121395_6	1229909.NSED_01460	4.488e-35	135.0	arCOG08822@1|root,arCOG08822@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5121395_2	1229909.NSED_01455	2.149e-125	403.0	COG0176@1|root,arCOG05061@2157|Archaea,41S99@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DYD2_k127_5146285_1	436308.Nmar_0109	4.222e-185	582.0	COG1537@1|root,arCOG01741@2157|Archaea,41S6V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	-	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_3
DYD2_k127_5146285_2	436308.Nmar_0108	2.932e-39	148.0	COG1324@1|root,arCOG04231@2157|Archaea,41SR4@651137|Thaumarchaeota	651137|Thaumarchaeota	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
DYD2_k127_5146285_0	436308.Nmar_0107	4.405e-214	669.0	COG0750@1|root,arCOG04064@2157|Archaea,41SW5@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
DYD2_k127_5181537_3	1229909.NSED_04775	1.047e-24	107.0	COG3353@1|root,arCOG01824@2157|Archaea	2157|Archaea	N	Archaeal flagellar protein F	flaF	-	-	ko:K07329	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
DYD2_k127_5181537_2	1229909.NSED_04790	3.696e-44	167.0	arCOG05517@1|root,arCOG05517@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5181537_0	1229909.NSED_04795	1.162e-199	624.0	COG0714@1|root,arCOG00441@2157|Archaea	2157|Archaea	V	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924,ko:K04748	-	-	R00294	RC02794	ko00000,ko01000	3.D.4.10	-	-	AAA_5,CbbQ_C,HHH_5
DYD2_k127_5181537_1	1229909.NSED_04800	8.886e-189	602.0	COG2304@1|root,arCOG02900@2157|Archaea	2157|Archaea	O	von Willebrand factor, type A	-	-	-	ko:K04043,ko:K07114	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko02000,ko03019,ko03029,ko03110,ko04147	1.A.13.2.2,1.A.13.2.3,1.A.33.1	-	-	HSP70,VWA,VWA_2
DYD2_k127_5211983_0	1229909.NSED_09245	4.903e-86	287.0	COG0431@1|root,arCOG04624@2157|Archaea,41T2F@651137|Thaumarchaeota	651137|Thaumarchaeota	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DYD2_k127_5211983_2	436308.Nmar_0200	6.141e-41	156.0	arCOG08634@1|root,arCOG08634@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5211983_1	436308.Nmar_1738	1.367e-64	224.0	arCOG08776@1|root,arCOG08776@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5211983_3	1229909.NSED_09255	8.733e-29	115.0	arCOG08769@1|root,arCOG08769@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5219148_0	436308.Nmar_1539	2.889e-237	737.0	COG1236@1|root,arCOG00541@2157|Archaea,41SAJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B_6,RMMBL
DYD2_k127_5219148_1	1229909.NSED_08465	1.075e-123	401.0	COG0122@1|root,arCOG00464@2157|Archaea,41SHE@651137|Thaumarchaeota	651137|Thaumarchaeota	L	8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
DYD2_k127_5225580_3	1229909.NSED_06090	4.725e-194	608.0	COG5256@1|root,arCOG01561@2157|Archaea,41SD2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DYD2_k127_5225580_2	1229909.NSED_06095	5.622e-224	696.0	COG1980@1|root,arCOG04180@2157|Archaea,41S67@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P)	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
DYD2_k127_5225580_7	436308.Nmar_1036	2.826e-61	213.0	arCOG08725@1|root,arCOG08725@2157|Archaea,41T3W@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5225580_1	436308.Nmar_1037	1.229e-310	959.0	COG1793@1|root,arCOG01347@2157|Archaea,41SCK@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
DYD2_k127_5225580_4	1229909.NSED_06110	6.183e-122	392.0	COG1392@1|root,arCOG02640@2157|Archaea,41SGI@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
DYD2_k127_5225580_5	436308.Nmar_1039	3.135e-99	325.0	COG1676@1|root,arCOG01701@2157|Archaea,41SHW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
DYD2_k127_5225580_8	1229909.NSED_06120	6.053e-60	209.0	arCOG08726@1|root,arCOG08726@2157|Archaea,41STN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5225580_9	1229909.NSED_06125	5.563e-36	139.0	arCOG08727@1|root,arCOG08727@2157|Archaea,41T57@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5225580_0	1229909.NSED_06130	1.21e-313	968.0	COG1028@1|root,arCOG01259@2157|Archaea,41S7V@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DYD2_k127_5225580_6	436308.Nmar_1044	5.038e-66	228.0	arCOG10570@1|root,arCOG10570@2157|Archaea,41T75@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5285890_0	1229909.NSED_07415	1.006e-152	484.0	COG2159@1|root,arCOG01931@2157|Archaea	2157|Archaea	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DYD2_k127_5285890_1	1229909.NSED_07420	3.784e-98	322.0	COG0456@1|root,arCOG00833@2157|Archaea	2157|Archaea	C	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
DYD2_k127_5350910_1	436308.Nmar_0196	1.932e-57	201.0	arCOG05565@1|root,arCOG05565@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5350910_2	436308.Nmar_0195	1.255e-30	123.0	arCOG08822@1|root,arCOG08822@2157|Archaea	436308.Nmar_0195|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5350910_0	102232.GLO73106DRAFT_00019640	1.628e-66	240.0	COG5640@1|root,COG5640@2|Bacteria,1G5D3@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Trypsin
DYD2_k127_5355985_0	1229909.NSED_09410	7.301e-190	598.0	COG0520@1|root,arCOG00065@2157|Archaea,41SYH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DYD2_k127_5355985_3	436308.Nmar_1762	2.146e-36	139.0	COG1522@1|root,arCOG01117@2157|Archaea,41T58@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD2_k127_5355985_1	1229909.NSED_09400	1.02e-98	325.0	COG1878@1|root,arCOG02462@2157|Archaea,41SK8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
DYD2_k127_5355985_2	1131266.ARWQ01000010_gene30	2.286e-96	317.0	COG1180@1|root,arCOG00946@2157|Archaea,41SBZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
DYD2_k127_5363103_4	1229909.NSED_06965	2.94e-06	51.0	arCOG08777@1|root,arCOG10350@1|root,arCOG08777@2157|Archaea,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5363103_0	1229909.NSED_05760	1.997e-111	366.0	arCOG01792@1|root,arCOG01792@2157|Archaea,41SFY@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DYD2_k127_5363103_1	1229909.NSED_05755	1.526e-94	321.0	arCOG08728@1|root,arCOG08733@1|root,arCOG08728@2157|Archaea,arCOG08733@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5363103_2	1229909.NSED_05750	1.132e-61	214.0	arCOG05565@1|root,arCOG05565@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5363103_3	436308.Nmar_0995	5.833e-42	154.0	COG0225@1|root,arCOG02816@2157|Archaea,41SMP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DYD2_k127_5386719_17	1229909.NSED_02660	4.029e-96	317.0	arCOG08739@1|root,arCOG08739@2157|Archaea,41SN6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5386719_19	436308.Nmar_0529	2.047e-68	234.0	COG0231@1|root,arCOG04277@2157|Archaea,41SNP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	-	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	eIF-5a
DYD2_k127_5386719_21	1459636.NTE_00775	7.142e-53	194.0	COG2102@1|root,arCOG00035@2157|Archaea,41SHD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Diphthamide synthase	-	-	6.3.1.14	ko:K06927	-	-	R03613	RC00358	ko00000,ko01000,ko03012	-	-	-	Diphthami_syn_2
DYD2_k127_5386719_1	1229909.NSED_02675	1.914e-257	796.0	COG0541@1|root,arCOG01228@2157|Archaea,41SDP@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DYD2_k127_5386719_11	1229909.NSED_02680	1.036e-152	491.0	COG1258@1|root,arCOG01015@2157|Archaea,41SHC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	-	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	-
DYD2_k127_5386719_14	436308.Nmar_0533	1.767e-125	404.0	arCOG08681@1|root,arCOG08681@2157|Archaea,41SH9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5386719_30	436308.Nmar_0304	2.458e-06	54.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5386719_25	436308.Nmar_0534	5.766e-25	105.0	COG1998@1|root,arCOG04183@2157|Archaea,41SWB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
DYD2_k127_5386719_22	436308.Nmar_0535	1.694e-52	188.0	COG2004@1|root,arCOG04182@2157|Archaea,41SWI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS24 family	-	-	-	ko:K02974	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	-
DYD2_k127_5386719_26	384616.Pisl_0363	2.588e-14	80.0	COG1547@1|root,arCOG03705@2157|Archaea,2XSMF@28889|Crenarchaeota	28889|Crenarchaeota	S	Domain of unknown function (DUF309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF309
DYD2_k127_5386719_2	436308.Nmar_0537	4.894e-235	732.0	COG3635@1|root,arCOG01696@2157|Archaea,41S6M@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
DYD2_k127_5386719_7	436308.Nmar_0538	1.345e-209	652.0	COG1085@1|root,arCOG00422@2157|Archaea,41S6T@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
DYD2_k127_5386719_23	1229909.NSED_02715	3.337e-40	153.0	arCOG08683@1|root,arCOG08683@2157|Archaea,41SUM@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5386719_20	1229909.NSED_02720	2.288e-60	211.0	COG0454@1|root,arCOG00826@2157|Archaea,41T2E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
DYD2_k127_5386719_15	1229909.NSED_02725	6.569e-113	368.0	COG1208@1|root,arCOG00663@2157|Archaea,41SGT@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DYD2_k127_5386719_9	436308.Nmar_0542	7.721e-173	552.0	COG0351@1|root,arCOG00020@2157|Archaea,41SA1@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Phosphomethylpyrimidine kinase	-	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K21219	ko00730,ko01100,map00730,map01100	-	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
DYD2_k127_5386719_28	1229909.NSED_02740	1.006e-13	72.0	COG1656@1|root,arCOG04290@2157|Archaea	2157|Archaea	L	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
DYD2_k127_5386719_0	436308.Nmar_0543	5.809e-271	836.0	COG0422@1|root,arCOG02741@2157|Archaea,41S5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein ThiC	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
DYD2_k127_5386719_27	309800.C498_04935	4.053e-14	77.0	COG1184@1|root,arCOG01127@2157|Archaea,2XUMH@28890|Euryarchaeota,23SF4@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eIF-2B alpha beta delta subunits family	tif2Ba	-	-	-	-	-	-	-	-	-	-	-	IF-2B,NUDIX
DYD2_k127_5386719_10	436308.Nmar_0545	9.131e-157	497.0	COG0722@1|root,arCOG00245@2157|Archaea,41SM0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
DYD2_k127_5386719_3	1229909.NSED_02765	8.659e-233	726.0	COG0436@1|root,COG1605@1|root,arCOG01130@2157|Archaea,arCOG02098@2157|Archaea,41SBV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Chorismate mutase type II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,CM_2
DYD2_k127_5386719_5	1229909.NSED_02770	3.153e-215	670.0	COG0082@1|root,arCOG04133@2157|Archaea,41SC3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DYD2_k127_5386719_6	436308.Nmar_0548	1.179e-212	666.0	COG0128@1|root,arCOG04134@2157|Archaea,41S5I@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
DYD2_k127_5386719_24	391623.TERMP_00424	6.732e-32	136.0	COG1685@1|root,arCOG01025@2157|Archaea,2XUI2@28890|Euryarchaeota,243I7@183968|Thermococci	183968|Thermococci	E	shikimate kinase activity	aroK	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
DYD2_k127_5386719_12	1229909.NSED_02790	3.85e-143	457.0	COG0169@1|root,arCOG01033@2157|Archaea,41S6G@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
DYD2_k127_5386719_16	436308.Nmar_0551	8.033e-103	338.0	COG0169@1|root,arCOG02097@2157|Archaea,41SKU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
DYD2_k127_5386719_8	436308.Nmar_0552	6.752e-205	640.0	COG1465@1|root,arCOG04353@2157|Archaea,41S88@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
DYD2_k127_5386719_13	1131266.ARWQ01000017_gene886	2.646e-135	434.0	COG1830@1|root,arCOG04044@2157|Archaea,41SCP@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
DYD2_k127_5386719_4	1229909.NSED_02810	3.832e-217	676.0	COG1060@1|root,arCOG00656@2157|Archaea,41SCN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
DYD2_k127_5386719_18	1229909.NSED_02815	2.74e-77	259.0	COG0043@1|root,arCOG01671@2157|Archaea,41S94@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DYD2_k127_5396797_5	436308.Nmar_0793	4.069e-48	173.0	arCOG08710@1|root,arCOG08710@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5396797_1	436308.Nmar_0794	2.146e-91	302.0	COG0097@1|root,arCOG04090@2157|Archaea,41SJG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
DYD2_k127_5396797_6	1229909.NSED_04420	1.147e-32	126.0	COG0199@1|root,arCOG00782@2157|Archaea,41SW8@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein S14	rps14	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
DYD2_k127_5396797_2	436308.Nmar_0797	8.406e-87	289.0	COG0094@1|root,arCOG04092@2157|Archaea,41SJP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
DYD2_k127_5396797_0	436308.Nmar_0798	1.675e-125	404.0	COG1471@1|root,arCOG04093@2157|Archaea,41SIE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS4 family	rps4e	-	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
DYD2_k127_5396797_4	1229909.NSED_04435	7.33e-56	199.0	COG0198@1|root,arCOG04094@2157|Archaea,41SSS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L26
DYD2_k127_5396797_3	1229909.NSED_04440	4.426e-77	259.0	COG0093@1|root,arCOG04095@2157|Archaea,41SHG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
DYD2_k127_5448043_0	1229909.NSED_07720	2.327e-238	741.0	COG2132@1|root,COG3794@1|root,arCOG02926@2157|Archaea,arCOG03914@2157|Archaea,41SWV@651137|Thaumarchaeota	651137|Thaumarchaeota	CQ	multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
DYD2_k127_5448043_3	1229909.NSED_06915	6.665e-65	225.0	COG1909@1|root,arCOG04076@2157|Archaea,41SNQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
DYD2_k127_5448043_1	436308.Nmar_1234	8.974e-209	653.0	COG0489@1|root,arCOG01846@1|root,arCOG00585@2157|Archaea,arCOG01846@2157|Archaea,41SF1@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
DYD2_k127_5448043_2	1229909.NSED_06925	2.491e-110	360.0	COG1095@1|root,arCOG00675@2157|Archaea,41SGF@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase	-	-	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
DYD2_k127_5448043_4	436308.Nmar_1236	1.123e-31	123.0	COG2093@1|root,arCOG04077@2157|Archaea,41SVE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
DYD2_k127_5448043_5	273075.Ta0475	1.376e-29	121.0	COG0675@1|root,arCOG00680@2157|Archaea,2Y8F7@28890|Euryarchaeota	28890|Euryarchaeota	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_Zn_ribbon
DYD2_k127_5468545_3	1229909.NSED_09195	3.522e-138	442.0	COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota	651137|Thaumarchaeota	S	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_7,Lactamase_B_6,RMMBL
DYD2_k127_5468545_5	436308.Nmar_1728	1.937e-127	409.0	COG0638@1|root,arCOG00970@2157|Archaea,41T1N@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
DYD2_k127_5468545_1	436308.Nmar_1729	3.518e-179	565.0	COG0371@1|root,arCOG00982@2157|Archaea,41T0B@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
DYD2_k127_5468545_2	1229909.NSED_09210	1.848e-138	442.0	COG1047@1|root,arCOG00980@2157|Archaea,41T0T@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
DYD2_k127_5468545_0	436308.Nmar_1731	8.349e-222	691.0	COG0075@1|root,arCOG00082@2157|Archaea,41SZZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DYD2_k127_5468545_6	1229909.NSED_09220	1.387e-79	267.0	COG1056@1|root,arCOG00972@2157|Archaea,41T7B@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DYD2_k127_5468545_4	1229909.NSED_09225	8.449e-138	446.0	COG0430@1|root,arCOG04125@2157|Archaea,41T1K@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC
DYD2_k127_5468545_8	1382356.JQMP01000004_gene542	1.733e-07	59.0	COG5615@1|root,COG5615@2|Bacteria,2GBBE@200795|Chloroflexi,27YNG@189775|Thermomicrobia	189775|Thermomicrobia	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	CopD
DYD2_k127_5468545_7	1229909.NSED_09235	4.485e-57	203.0	arCOG03788@1|root,arCOG03788@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
DYD2_k127_5475195_1	436308.Nmar_0197	4.743e-53	189.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5475195_0	1131266.ARWQ01000014_gene87	4.608e-54	196.0	COG4122@1|root,arCOG00979@2157|Archaea,41SMF@651137|Thaumarchaeota	651137|Thaumarchaeota	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
DYD2_k127_5475195_2	436308.Nmar_0999	1.599e-52	202.0	arCOG10350@1|root,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5475195_3	436308.Nmar_1636	0.000171	44.0	arCOG08812@1|root,arCOG08812@2157|Archaea	436308.Nmar_1636|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5531293_1	1229909.NSED_00350	7.582e-67	230.0	arCOG10517@1|root,arCOG10517@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5531293_3	1229909.NSED_00345	3.687e-40	149.0	arCOG10516@1|root,arCOG10516@2157|Archaea,41T5R@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5531293_2	1249975.JQLP01000005_gene2506	1.137e-63	234.0	COG1357@1|root,COG1361@1|root,COG1520@1|root,COG2304@1|root,COG2911@1|root,COG1357@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,4NMB8@976|Bacteroidetes,1IJKA@117743|Flavobacteriia	976|Bacteroidetes	M	Pfam C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SdrD_B
DYD2_k127_5531293_0	436308.Nmar_0173	1.614e-113	369.0	COG1028@1|root,arCOG01259@2157|Archaea,41SYZ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DYD2_k127_5531293_4	436308.Nmar_0172	5.278e-26	107.0	COG2151@1|root,arCOG03838@1|root,arCOG01845@2157|Archaea,arCOG03838@2157|Archaea,41SHR@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P,PqqD
DYD2_k127_5638369_16	1229909.NSED_05280	1.201e-26	112.0	arCOG06883@1|root,arCOG06883@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334,DZR
DYD2_k127_5638369_0	1229909.NSED_05285	2.418e-297	917.0	COG4962@1|root,arCOG01817@2157|Archaea,41T25@651137|Thaumarchaeota	651137|Thaumarchaeota	N	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
DYD2_k127_5638369_1	1229909.NSED_05290	2.683e-153	488.0	COG2064@1|root,arCOG01808@2157|Archaea	2157|Archaea	NU	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DYD2_k127_5638369_2	1229909.NSED_05295	2.218e-146	468.0	COG2064@1|root,arCOG01808@2157|Archaea	2157|Archaea	NU	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
DYD2_k127_5638369_3	1229909.NSED_05300	3.328e-135	435.0	COG1378@1|root,arCOG02038@2157|Archaea	2157|Archaea	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
DYD2_k127_5638369_8	1229909.NSED_05305	2.001e-68	235.0	arCOG04006@1|root,arCOG04006@2157|Archaea	2157|Archaea	C	HEAT repeats	-	-	1.14.99.29	ko:K06072	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2
DYD2_k127_5638369_20	1185876.BN8_00027	3.055e-12	72.0	COG2940@1|root,COG2940@2|Bacteria,4NM5I@976|Bacteroidetes,47WYB@768503|Cytophagia	976|Bacteroidetes	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
DYD2_k127_5638369_9	1229909.NSED_05310	1.231e-66	235.0	arCOG10526@1|root,arCOG10526@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5638369_6	1229909.NSED_05315	5.008e-86	289.0	COG0640@1|root,arCOG03067@2157|Archaea	2157|Archaea	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD2_k127_5638369_7	1229909.NSED_05320	9.179e-84	280.0	arCOG08805@1|root,arCOG08805@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5638369_4	1229909.NSED_05325	1.141e-128	421.0	COG0697@1|root,arCOG00273@2157|Archaea	2157|Archaea	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD2_k127_5638369_5	1229909.NSED_05330	4.519e-124	404.0	COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DYD2_k127_5638369_10	1229909.NSED_05335	2.246e-66	229.0	COG4911@1|root,arCOG05495@2157|Archaea,41SNJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
DYD2_k127_5638369_15	436308.Nmar_0940	4.086e-37	141.0	arCOG10567@1|root,arCOG10567@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5638369_12	436308.Nmar_0941	2.142e-52	188.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41T4V@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
DYD2_k127_5638369_14	1229909.NSED_05350	2.16e-39	150.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K03413,ko:K07662,ko:K07667	ko01503,ko02020,ko02024,ko02030,map01503,map02020,map02024,map02030	M00447,M00454,M00506,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CHASE4,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
DYD2_k127_5638369_19	1229909.NSED_05360	5.171e-18	85.0	COG0784@1|root,arCOG02391@2157|Archaea,41T9J@651137|Thaumarchaeota	2157|Archaea	T	COG0784 FOG CheY-like receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD2_k127_5638369_18	436308.Nmar_1619	6.149e-19	91.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD2_k127_5638369_11	436308.Nmar_0464	6.003e-56	201.0	COG0640@1|root,arCOG03067@2157|Archaea	2157|Archaea	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD2_k127_5638369_17	436308.Nmar_1619	1.072e-21	98.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD2_k127_5638369_13	436308.Nmar_0942	5.913e-47	169.0	COG0760@1|root,arCOG07441@2157|Archaea,41SSK@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
DYD2_k127_5641026_7	1131266.ARWQ01000004_gene1476	2.424e-118	386.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DYD2_k127_5641026_0	1229909.NSED_07310	0.0	1438.0	COG1205@1|root,arCOG08693@1|root,arCOG00555@2157|Archaea,arCOG08693@2157|Archaea,41SZS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
DYD2_k127_5641026_14	760142.Hipma_0748	0.000683	47.0	COG3462@1|root,COG3462@2|Bacteria,1PXB4@1224|Proteobacteria,434EK@68525|delta/epsilon subdivisions,2WYRZ@28221|Deltaproteobacteria,2M7PI@213113|Desulfurellales	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
DYD2_k127_5641026_4	436308.Nmar_1319	7.011e-146	465.0	COG0863@1|root,arCOG00115@2157|Archaea,41SZP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA methylase	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
DYD2_k127_5641026_13	436308.Nmar_1318	3.381e-38	145.0	COG1826@1|root,arCOG02694@2157|Archaea,41SRR@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
DYD2_k127_5641026_12	1229909.NSED_07295	3.603e-42	156.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2226,P-II
DYD2_k127_5641026_3	436308.Nmar_1316	1.084e-198	624.0	COG0477@1|root,arCOG00130@2157|Archaea,41T0X@651137|Thaumarchaeota	651137|Thaumarchaeota	G	major facilitator superfamily	-	-	-	ko:K08153,ko:K08221	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8,2.A.1.32	-	-	MFS_1
DYD2_k127_5641026_6	436308.Nmar_1315	5.679e-127	408.0	COG2226@1|root,arCOG04348@2157|Archaea,41SGQ@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
DYD2_k127_5641026_5	1229909.NSED_07280	1.761e-132	424.0	COG0638@1|root,arCOG00971@2157|Archaea,41SYA@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Proteasome endopeptidase complex	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
DYD2_k127_5641026_10	436308.Nmar_1313	2.123e-57	201.0	COG0640@1|root,arCOG00731@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
DYD2_k127_5641026_2	436308.Nmar_1312	1.819e-252	781.0	COG0334@1|root,arCOG01352@2157|Archaea,41S7T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DYD2_k127_5641026_11	436308.Nmar_1311	3.789e-54	192.0	COG1658@1|root,arCOG01486@2157|Archaea,41SU4@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Toprim domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5641026_8	1229909.NSED_07255	8.829e-111	361.0	COG0518@1|root,arCOG00090@2157|Archaea,41T3Z@651137|Thaumarchaeota	651137|Thaumarchaeota	F	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
DYD2_k127_5641026_1	1229909.NSED_07250	0.0	1295.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S7I@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18594	ko00720,ko01120,map00720,map01120	-	R03157	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
DYD2_k127_5641026_9	436308.Nmar_1308	1.612e-87	290.0	COG1024@1|root,arCOG00239@2157|Archaea,41SH7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.116	ko:K15019	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00375	R03045	RC00834	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DYD2_k127_5714612_1	1229909.NSED_03205	1.209e-57	201.0	COG0023@1|root,arCOG04223@2157|Archaea,41SNU@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the SUI1 family	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
DYD2_k127_5714612_2	436308.Nmar_0621	1.098e-41	156.0	COG1645@1|root,arCOG00578@2157|Archaea,41SVN@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)	-	-	-	ko:K07143	-	-	-	-	ko00000	-	-	-	Auto_anti-p27
DYD2_k127_5714612_3	1229909.NSED_09025	6.646e-29	120.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	2.7.13.3	ko:K07646,ko:K20989	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	2.A.21.6	-	-	DUF4118,GAF_3,KdpD,Usp
DYD2_k127_5714612_0	1229909.NSED_01810	4.615e-100	336.0	COG1808@1|root,arCOG02264@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
DYD2_k127_5781391_8	436308.Nmar_0951	1.461e-10	64.0	COG0574@1|root,arCOG01111@2157|Archaea,41SYV@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Pyruvate phosphate dikinase	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DYD2_k127_5781391_4	436308.Nmar_0952	1.538e-97	320.0	COG3620@1|root,arCOG00608@2157|Archaea,41SJR@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_3
DYD2_k127_5781391_5	1229909.NSED_00340	3.787e-77	267.0	arCOG08796@1|root,arCOG08796@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5781391_6	1229909.NSED_05435	1.319e-73	248.0	COG0346@1|root,arCOG02706@2157|Archaea,41SQS@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
DYD2_k127_5781391_1	1229909.NSED_07405	8.542e-223	702.0	COG0598@1|root,arCOG02265@2157|Archaea	2157|Archaea	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DYD2_k127_5781391_0	1229909.NSED_05460	1.861e-303	935.0	COG1884@1|root,arCOG04232@2157|Archaea,41SBW@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DYD2_k127_5781391_3	436308.Nmar_0955	1.03e-151	484.0	COG1703@1|root,arCOG01226@2157|Archaea,41SFN@651137|Thaumarchaeota	651137|Thaumarchaeota	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DYD2_k127_5781391_7	436308.Nmar_0956	8.714e-39	149.0	arCOG08685@1|root,arCOG08685@2157|Archaea,41T67@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5781391_2	1229909.NSED_05490	9.906e-170	536.0	COG0308@1|root,arCOG02969@2157|Archaea,41SJH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256,ko:K13722	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
DYD2_k127_5828130_4	436308.Nmar_1529	1.544e-129	415.0	COG0731@1|root,arCOG04174@2157|Archaea,41SBS@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
DYD2_k127_5828130_8	387631.Asulf_01092	3.702e-42	162.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,24673@183980|Archaeoglobi	183980|Archaeoglobi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DYD2_k127_5828130_5	1229909.NSED_08420	4.933e-98	323.0	COG0533@1|root,arCOG01185@2157|Archaea,41SJJ@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Mn2 -dependent serine threonine protein kinase	-	-	2.7.11.1	ko:K08851	-	-	-	-	ko00000,ko01000,ko01001,ko03016	-	-	-	Pkinase
DYD2_k127_5828130_0	1229909.NSED_05805	3.264e-309	955.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
DYD2_k127_5828130_7	1229909.NSED_08425	5.972e-48	173.0	arCOG10590@1|root,arCOG10590@2157|Archaea,41SSG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5828130_3	436308.Nmar_1533	1.334e-190	597.0	COG0533@1|root,arCOG01183@2157|Archaea,41SDX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37	kae1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DYD2_k127_5828130_2	1229909.NSED_08435	2.836e-215	673.0	COG0012@1|root,arCOG00357@2157|Archaea,41S71@651137|Thaumarchaeota	651137|Thaumarchaeota	J	GTPase of unknown function C-terminal	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
DYD2_k127_5828130_6	1229909.NSED_08440	1.398e-68	237.0	COG1936@1|root,arCOG01038@2157|Archaea,41SPH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
DYD2_k127_5828130_1	1229909.NSED_08445	6.109e-272	842.0	COG0343@1|root,arCOG00989@2157|Archaea,41SF4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	-	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TGT
DYD2_k127_583403_3	436308.Nmar_0064	1.003e-155	494.0	COG0648@1|root,arCOG01894@2157|Archaea,41SDW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
DYD2_k127_583403_2	1229909.NSED_00020	1.061e-165	526.0	COG2219@1|root,arCOG03013@2157|Archaea,41SCD@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priL	-	-	ko:K18882	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_lrg
DYD2_k127_583403_1	1229909.NSED_00025	1.306e-199	626.0	COG1467@1|root,arCOG04110@2157|Archaea,41SCB@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	-	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
DYD2_k127_583403_0	436308.Nmar_0067	0.0	1483.0	COG1615@1|root,arCOG06128@2157|Archaea,41SCS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
DYD2_k127_5847034_0	436308.Nmar_0333	1.711e-281	881.0	arCOG08778@1|root,arCOG08778@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5847034_1	436308.Nmar_0332	1.059e-74	252.0	COG0053@1|root,arCOG01474@2157|Archaea,arCOG01475@2157|Archaea,41SXN@651137|Thaumarchaeota	651137|Thaumarchaeota	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DYD2_k127_599109_1	1229909.NSED_01260	3.651e-26	107.0	COG4799@1|root,arCOG02705@2157|Archaea,41SEH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18604	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
DYD2_k127_599109_0	436308.Nmar_0273	1.6e-278	861.0	COG0439@1|root,arCOG01590@2157|Archaea,41SXC@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Carbamoyl-phosphate synthase L chain	-	-	6.4.1.2,6.4.1.3	ko:K18603	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DYD2_k127_599500_2	436308.Nmar_1259	3.333e-64	221.0	COG2132@1|root,arCOG03914@2157|Archaea,41SZT@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3
DYD2_k127_599500_0	436308.Nmar_1258	7.439e-174	548.0	COG0111@1|root,arCOG01754@2157|Archaea,41S8U@651137|Thaumarchaeota	651137|Thaumarchaeota	H	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DYD2_k127_599500_1	436308.Nmar_1257	2.386e-69	245.0	arCOG08033@1|root,arCOG08033@2157|Archaea	2157|Archaea	C	copper ion binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_599500_4	1229909.NSED_07045	7.535e-62	216.0	arCOG12843@1|root,arCOG12843@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_599500_3	436308.Nmar_1255	2.122e-63	224.0	arCOG08778@1|root,arCOG08778@2157|Archaea,41T5W@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_599500_5	1229909.NSED_07030	8.287e-09	57.0	COG1632@1|root,arCOG04209@2157|Archaea,41SND@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein L15E	-	-	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
DYD2_k127_6005437_2	1459636.NTE_01122	4.582e-51	185.0	COG0783@1|root,arCOG01101@2157|Archaea	2157|Archaea	P	Belongs to the Dps family	frt	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
DYD2_k127_6005437_3	1229909.NSED_06895	3.432e-48	173.0	arCOG08720@1|root,arCOG08720@2157|Archaea,41STI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF2024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2024
DYD2_k127_6005437_4	1229909.NSED_06900	7.785e-25	104.0	arCOG08719@1|root,arCOG08719@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6005437_0	436308.Nmar_1231	0.0	1112.0	COG3808@1|root,arCOG04949@2157|Archaea,41SZG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
DYD2_k127_6005437_1	1229909.NSED_06910	8.079e-60	207.0	arCOG08718@1|root,arCOG08718@2157|Archaea,41T2G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	-
DYD2_k127_604245_8	1229909.NSED_02355	8.726e-15	87.0	arCOG08733@1|root,arCOG08733@2157|Archaea,41SRN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_604245_6	1459636.NTE_01313	1.383e-75	273.0	arCOG08812@1|root,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_604245_2	436308.Nmar_1649	1.592e-110	362.0	arCOG10597@1|root,arCOG10597@2157|Archaea	2157|Archaea	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_604245_5	1229909.NSED_08935	4.095e-84	288.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD2_k127_604245_3	436308.Nmar_1651	4.677e-90	301.0	arCOG08794@1|root,arCOG08794@2157|Archaea,41SR7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_604245_0	436308.Nmar_1652	0.0	1290.0	COG4257@1|root,arCOG06267@1|root,arCOG03564@2157|Archaea,arCOG06267@2157|Archaea,41S5S@651137|Thaumarchaeota	651137|Thaumarchaeota	V	resistance protein	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
DYD2_k127_604245_4	1459636.NTE_00034	1.777e-87	297.0	COG1108@1|root,arCOG01006@2157|Archaea,41SG2@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
DYD2_k127_604245_1	1229909.NSED_08955	2.295e-123	396.0	COG1121@1|root,arCOG00201@2157|Archaea,41S7E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
DYD2_k127_6093159_10	436308.Nmar_1369	1.222e-23	100.0	arCOG08651@1|root,arCOG08651@2157|Archaea,41TB6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6093159_3	436308.Nmar_1368	9.168e-153	484.0	COG0457@1|root,arCOG03038@2157|Archaea,41SMV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
DYD2_k127_6093159_2	436308.Nmar_1367	3.366e-199	627.0	arCOG08650@1|root,arCOG08650@2157|Archaea,41SZ5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6093159_5	1229909.NSED_07475	6.779e-118	385.0	COG0500@1|root,COG2835@1|root,arCOG01791@2157|Archaea,arCOG04124@2157|Archaea,41T4S@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6093159_11	1131462.DCF50_p1814	7.125e-09	58.0	2EJHG@1|root,33D8E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6093159_4	1229909.NSED_04505	2.116e-149	484.0	COG2133@1|root,arCOG02796@2157|Archaea,41T0Q@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
DYD2_k127_6093159_7	436308.Nmar_0196	6.836e-57	200.0	arCOG05565@1|root,arCOG05565@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6093159_9	436308.Nmar_0195	2.777e-28	115.0	arCOG08822@1|root,arCOG08822@2157|Archaea	436308.Nmar_0195|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6093159_6	1229909.NSED_00905	1.635e-67	239.0	arCOG07526@1|root,arCOG07526@2157|Archaea	2157|Archaea	L	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
DYD2_k127_6093159_8	1229909.NSED_03455	3.434e-32	130.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_6093159_1	1041930.Mtc_1620	1.843e-262	828.0	COG2217@1|root,COG3350@1|root,arCOG01576@2157|Archaea,arCOG04507@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DYD2_k127_6093159_0	1229909.NSED_07320	2.144e-308	950.0	COG3569@1|root,arCOG08649@2157|Archaea,41SDH@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA Topoisomerase I (eukaryota)	-	-	5.99.1.2	ko:K03163	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topo_C_assoc,Topoisom_I,Topoisom_I_N
DYD2_k127_6115941_6	1131266.ARWQ01000009_gene927	5.513e-07	51.0	COG0388@1|root,arCOG00062@2157|Archaea,41SF8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
DYD2_k127_6115941_2	1229909.NSED_08895	6.038e-80	268.0	arCOG10412@1|root,arCOG10412@2157|Archaea,41SS9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6115941_1	1229909.NSED_08890	6.978e-240	743.0	COG0183@1|root,arCOG01278@2157|Archaea,41SCI@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD2_k127_6115941_3	1131266.ARWQ01000009_gene924	5.819e-39	149.0	COG1545@1|root,arCOG01285@2157|Archaea,41SQK@651137|Thaumarchaeota	651137|Thaumarchaeota	V	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
DYD2_k127_6115941_4	436308.Nmar_1629	6.813e-28	113.0	arCOG08792@1|root,arCOG08792@2157|Archaea,41SUG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6115941_0	1229909.NSED_08875	0.0	1190.0	COG0640@1|root,COG1328@1|root,arCOG01680@2157|Archaea,arCOG04889@2157|Archaea,41SBG@651137|Thaumarchaeota	651137|Thaumarchaeota	FK	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,HTH_20,NRDD
DYD2_k127_6115941_5	436308.Nmar_1627	1.136e-18	85.0	COG0209@1|root,arCOG03713@1|root,arCOG03713@2157|Archaea,arCOG04276@2157|Archaea,41SAH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
DYD2_k127_6154090_33	1229909.NSED_06965	1.525e-05	53.0	arCOG08777@1|root,arCOG10350@1|root,arCOG08777@2157|Archaea,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_12	1229909.NSED_05760	1.174e-112	369.0	arCOG01792@1|root,arCOG01792@2157|Archaea,41SFY@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
DYD2_k127_6154090_14	1229909.NSED_05755	3.671e-92	315.0	arCOG08728@1|root,arCOG08733@1|root,arCOG08728@2157|Archaea,arCOG08733@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_22	1229909.NSED_05750	8.078e-63	218.0	arCOG05565@1|root,arCOG05565@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_17	1229909.NSED_05740	4.555e-79	265.0	COG0225@1|root,arCOG02816@2157|Archaea,41SMP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DYD2_k127_6154090_28	1229909.NSED_05735	4.439e-43	162.0	COG0589@1|root,arCOG02053@2157|Archaea,41TB2@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_6154090_10	1229909.NSED_05730	2.528e-123	399.0	COG0596@1|root,arCOG01648@2157|Archaea,41SFU@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DYD2_k127_6154090_19	436308.Nmar_0993	1.862e-69	237.0	arCOG03937@1|root,arCOG03937@2157|Archaea,41SWM@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG2002 Regulators of stationary sporulation gene expression	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_18	1229909.NSED_05720	5.023e-70	239.0	arCOG08754@1|root,arCOG08754@2157|Archaea,41SUV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_4	1229909.NSED_05715	1.402e-218	679.0	COG3243@1|root,arCOG06344@2157|Archaea,41SEX@651137|Thaumarchaeota	651137|Thaumarchaeota	I	TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
DYD2_k127_6154090_13	1229909.NSED_05710	6.011e-96	316.0	arCOG06343@1|root,arCOG06343@2157|Archaea,41SRX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
DYD2_k127_6154090_23	436308.Nmar_0989	9.489e-57	200.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41ST4@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_25	1229909.NSED_05700	1.473e-48	177.0	COG2236@1|root,arCOG00040@2157|Archaea,41TA1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosyltransferase	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	-
DYD2_k127_6154090_6	436308.Nmar_0987	9.23e-174	547.0	COG1405@1|root,arCOG01981@2157|Archaea,41SYU@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
DYD2_k127_6154090_5	436308.Nmar_0986	5.16e-204	645.0	COG0457@1|root,COG5549@1|root,arCOG03038@2157|Archaea,arCOG04994@2157|Archaea,41T10@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,TPR_8
DYD2_k127_6154090_30	1229909.NSED_05685	5.079e-32	128.0	arCOG08756@1|root,arCOG08756@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_8	436308.Nmar_0984	1.485e-157	502.0	COG0340@1|root,arCOG01940@2157|Archaea,41SI3@651137|Thaumarchaeota	651137|Thaumarchaeota	H	biotin-(Acetyl-CoA-carboxylase) ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
DYD2_k127_6154090_20	1229909.NSED_05675	1.587e-66	230.0	COG1846@1|root,arCOG03748@2157|Archaea,41T7R@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_21	1229909.NSED_05670	2.938e-63	221.0	COG1832@1|root,arCOG04227@2157|Archaea,41SMT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
DYD2_k127_6154090_26	436308.Nmar_0981	6.759e-45	166.0	arCOG05491@1|root,arCOG05491@2157|Archaea,41SVB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_3	436308.Nmar_0980	6.423e-233	723.0	COG0012@1|root,arCOG00357@2157|Archaea,41S8X@651137|Thaumarchaeota	651137|Thaumarchaeota	J	GTPase of unknown function C-terminal	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
DYD2_k127_6154090_32	1229909.NSED_05075	9.366e-07	52.0	arCOG11444@1|root,arCOG11444@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_27	1229909.NSED_05595	3.18e-43	158.0	arCOG08644@1|root,arCOG08644@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6154090_2	436308.Nmar_0967	7.335e-244	760.0	COG0215@1|root,arCOG00486@2157|Archaea,41SEW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PFAM tRNA synthetases class I (C) catalytic domain	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
DYD2_k127_6154090_9	1229909.NSED_05565	1.125e-123	401.0	COG0171@1|root,arCOG00069@2157|Archaea,41SJ9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
DYD2_k127_6154090_24	1229909.NSED_05555	5.151e-55	193.0	COG2146@1|root,arCOG02854@2157|Archaea,41STC@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
DYD2_k127_6154090_1	1229909.NSED_05550	6.699e-257	794.0	COG0499@1|root,arCOG04137@2157|Archaea,41S9I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DYD2_k127_6154090_0	1229909.NSED_05545	0.0	1017.0	COG0143@1|root,arCOG00810@2157|Archaea,41SAF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
DYD2_k127_6154090_11	436308.Nmar_0962	1.278e-122	397.0	arCOG07550@1|root,arCOG07550@2157|Archaea,41SXF@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF726
DYD2_k127_6154090_7	436308.Nmar_0961	1.485e-163	518.0	COG3276@1|root,arCOG01564@2157|Archaea,41SCR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	elongation factor Tu	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
DYD2_k127_6154090_16	436308.Nmar_0960	1.34e-87	291.0	COG1056@1|root,arCOG00972@2157|Archaea,41T2U@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
DYD2_k127_6154090_15	436308.Nmar_0959	8.413e-89	294.0	COG0059@1|root,arCOG04465@2157|Archaea,41S65@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
DYD2_k127_618869_4	436308.Nmar_1227	3.262e-56	199.0	COG1310@1|root,arCOG01138@2157|Archaea,41SSV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
DYD2_k127_618869_3	1229909.NSED_06875	1.493e-154	495.0	COG3794@1|root,arCOG02926@2157|Archaea,arCOG02929@2157|Archaea,41SHN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD2_k127_618869_2	436308.Nmar_1225	1.768e-158	503.0	COG0109@1|root,arCOG00479@2157|Archaea,41SDQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DYD2_k127_618869_6	436308.Nmar_1224	3.613e-39	147.0	arCOG07192@1|root,arCOG07192@2157|Archaea,41SVA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_618869_0	1229909.NSED_06860	0.0	1296.0	COG0464@1|root,arCOG01308@2157|Archaea,41S7X@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48) domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
DYD2_k127_618869_5	436308.Nmar_1222	2.824e-39	149.0	COG2092@1|root,arCOG01988@2157|Archaea,41SS1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
DYD2_k127_618869_8	1229909.NSED_06850	8.906e-30	118.0	COG2888@1|root,arCOG01989@2157|Archaea,41T83@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Zn-ribbon RNA-binding protein with a function in translation	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	-
DYD2_k127_618869_1	436308.Nmar_1220	1.35e-203	638.0	COG0644@1|root,arCOG00570@2157|Archaea,41SB5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_618869_9	1028800.RG540_CH11150	0.0004454	49.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,2U8GF@28211|Alphaproteobacteria,4BMTX@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Fic/DOC family	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
DYD2_k127_618869_7	436308.Nmar_1200	1.251e-32	128.0	COG1990@1|root,arCOG04228@2157|Archaea,41ST1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Peptidyl-tRNA hydrolase PTH2	-	-	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
DYD2_k127_6199898_1	1229909.NSED_05245	3.845e-69	236.0	COG1575@1|root,arCOG00480@2157|Archaea,41S8H@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DYD2_k127_6199898_0	1229909.NSED_05255	1.274e-302	947.0	arCOG11939@1|root,arCOG11939@2157|Archaea	1229909.NSED_05255|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6203195_1	436308.Nmar_1633	1.277e-150	484.0	COG0388@1|root,arCOG00062@2157|Archaea,41SF8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
DYD2_k127_6203195_3	1229909.NSED_08905	1.051e-29	118.0	arCOG02240@1|root,arCOG02240@2157|Archaea,41SSM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
DYD2_k127_6203195_2	1131266.ARWQ01000009_gene929	3.923e-122	395.0	COG0705@1|root,arCOG01768@2157|Archaea,41SKD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DYD2_k127_6203195_0	436308.Nmar_1644	3.338e-180	572.0	arCOG08728@1|root,arCOG08728@2157|Archaea,41SW1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6240761_7	436308.Nmar_0890	3.519e-22	97.0	arCOG11730@1|root,arCOG11730@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6240761_6	1229909.NSED_05140	6.282e-24	102.0	COG5549@1|root,arCOG04994@2157|Archaea,41TAJ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Peptidase M10A and M12B matrixin and adamalysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
DYD2_k127_6240761_1	1229909.NSED_03790	6.245e-194	616.0	COG0277@1|root,arCOG00337@2157|Archaea,41T0E@651137|Thaumarchaeota	651137|Thaumarchaeota	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
DYD2_k127_6240761_5	1229909.NSED_03770	1.103e-42	159.0	arCOG08757@1|root,arCOG08757@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6240761_2	1229909.NSED_03760	9.618e-111	361.0	COG0605@1|root,arCOG04147@2157|Archaea,41S6C@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
DYD2_k127_6240761_3	1229909.NSED_08350	7.773e-104	339.0	COG2101@1|root,arCOG01764@2157|Archaea,41SZD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	-	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
DYD2_k127_6240761_4	436308.Nmar_0727	3.629e-56	202.0	arCOG08797@1|root,arCOG08797@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6240761_0	1229909.NSED_03750	4.287e-284	876.0	COG0553@1|root,arCOG00883@2157|Archaea,41T0G@651137|Thaumarchaeota	651137|Thaumarchaeota	K	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
DYD2_k127_643092_18	1122915.AUGY01000014_gene2747	1.569e-08	56.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1VCNJ@1239|Firmicutes,4HU5T@91061|Bacilli,2778V@186822|Paenibacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
DYD2_k127_643092_6	1229909.NSED_03065	1.714e-121	392.0	COG1938@1|root,arCOG00347@2157|Archaea,41SSA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
DYD2_k127_643092_3	436308.Nmar_0582	5.475e-188	593.0	COG0150@1|root,arCOG00639@2157|Archaea,41SEE@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DYD2_k127_643092_2	1229909.NSED_03055	2.35e-199	627.0	COG0475@1|root,arCOG01953@2157|Archaea,41T00@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DYD2_k127_643092_1	1229909.NSED_03045	1.123e-302	932.0	COG1243@1|root,arCOG01361@2157|Archaea,41S9N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Histone acetyltransferase	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
DYD2_k127_643092_0	436308.Nmar_0578	3.75e-307	945.0	COG1384@1|root,arCOG00485@2157|Archaea,41SB4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
DYD2_k127_643092_16	1229909.NSED_03035	4.548e-17	82.0	arCOG10985@1|root,arCOG10985@2157|Archaea,41T8V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_643092_10	436308.Nmar_0577	1.008e-64	230.0	arCOG08034@1|root,arCOG08034@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_643092_15	1229909.NSED_03010	1.351e-27	112.0	arCOG08736@1|root,arCOG08736@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_643092_14	1229909.NSED_03015	6.851e-43	158.0	arCOG08710@1|root,arCOG08710@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_643092_9	1229909.NSED_03000	5.97e-81	272.0	COG1528@1|root,arCOG01095@2157|Archaea	2157|Archaea	P	PFAM Ferritin, Dps family protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
DYD2_k127_643092_13	1229909.NSED_02990	5.694e-48	173.0	arCOG11305@1|root,arCOG11305@2157|Archaea,41T7G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_643092_7	1229909.NSED_02985	1.394e-91	304.0	COG2818@1|root,arCOG06523@2157|Archaea	2157|Archaea	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DYD2_k127_643092_11	1229909.NSED_02980	4.901e-60	210.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41T4K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_643092_5	1229909.NSED_02970	9.018e-124	404.0	COG0412@1|root,arCOG10350@1|root,arCOG01659@2157|Archaea,arCOG10350@2157|Archaea,41T1E@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Chlorophyllase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
DYD2_k127_643092_4	1229909.NSED_02835	7.361e-130	417.0	COG0580@1|root,arCOG04431@2157|Archaea,41S5R@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Major Intrinsic Protein	-	-	-	ko:K06188,ko:K09866	ko04962,ko04976,map04962,map04976	-	-	-	ko00000,ko00001,ko02000	1.A.8	-	-	MIP
DYD2_k127_643092_8	436308.Nmar_0560	9.56e-87	288.0	COG1225@1|root,arCOG00310@2157|Archaea,41SN5@651137|Thaumarchaeota	651137|Thaumarchaeota	O	AhpC/TSA antioxidant enzyme	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DYD2_k127_643092_12	436308.Nmar_0559	2.109e-50	183.0	arCOG08027@1|root,arCOG08027@2157|Archaea,41T8U@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6486835_1	436308.Nmar_0316	4.283e-113	367.0	COG0052@1|root,arCOG04245@2157|Archaea,41SG7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS2 family	rps2	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DYD2_k127_6486835_0	436308.Nmar_0317	3.45e-222	693.0	COG0148@1|root,arCOG01169@2157|Archaea,41SE9@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DYD2_k127_6486835_2	436308.Nmar_0318	1.587e-47	171.0	COG1644@1|root,arCOG04244@2157|Archaea,41SPN@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoN	-	2.7.7.6	ko:K03058	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_N
DYD2_k127_6493636_1	436308.Nmar_0090	7.027e-162	512.0	COG1131@1|root,arCOG00194@2157|Archaea,41TB8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD2_k127_6493636_0	436308.Nmar_0089	1.397e-162	515.0	COG1599@1|root,arCOG01510@2157|Archaea,41S9M@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
DYD2_k127_6502390_12	1229909.NSED_09285	1.217e-45	169.0	arCOG08767@1|root,arCOG08767@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6502390_4	1229909.NSED_09290	1.507e-168	531.0	COG0524@1|root,arCOG00014@2157|Archaea,41SX4@651137|Thaumarchaeota	651137|Thaumarchaeota	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DYD2_k127_6502390_9	436308.Nmar_1746	1.036e-58	204.0	arCOG08766@1|root,arCOG08766@2157|Archaea,41T41@651137|Thaumarchaeota	651137|Thaumarchaeota	G	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
DYD2_k127_6502390_8	1229909.NSED_09300	4.855e-67	231.0	COG4063@1|root,arCOG03220@2157|Archaea,41T46@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrahydromethanopterin S-methyltransferase, subunit A	-	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
DYD2_k127_6502390_3	1229909.NSED_09305	5.343e-191	600.0	COG0399@1|root,arCOG00118@2157|Archaea,41S96@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
DYD2_k127_6502390_7	1229909.NSED_09310	8.975e-97	318.0	arCOG08765@1|root,arCOG08765@2157|Archaea,41SQJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6502390_13	1229909.NSED_09315	9.522e-27	109.0	arCOG08679@1|root,arCOG08679@2157|Archaea	2157|Archaea	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6502390_14	436308.Nmar_1750	1.057e-26	110.0	arCOG10602@1|root,arCOG10602@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6502390_2	1229909.NSED_09325	1.667e-197	619.0	COG0162@1|root,arCOG01886@2157|Archaea,41S8C@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Tyrosine--tRNA ligase	-	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
DYD2_k127_6502390_5	1229909.NSED_09330	4.936e-161	509.0	COG1010@1|root,arCOG00647@2157|Archaea,41S6W@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.131	ko:K05934	ko00860,ko01100,map00860,map01100	-	R05180,R05809	RC00003,RC01293,RC03471	ko00000,ko00001,ko01000	-	-	-	TP_methylase
DYD2_k127_6502390_1	436308.Nmar_1753	1.704e-212	669.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6502390_0	436308.Nmar_1754	2.426e-246	766.0	COG0527@1|root,arCOG00861@2157|Archaea,41SFA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
DYD2_k127_6502390_6	1229909.NSED_09345	1.141e-146	466.0	COG0592@1|root,arCOG00488@2157|Archaea,41S6E@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	-	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
DYD2_k127_6502390_11	436308.Nmar_1756	6.409e-46	167.0	COG1594@1|root,arCOG00579@2157|Archaea,41SS3@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	-	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	TFIIS_C
DYD2_k127_6502390_10	1229909.NSED_09355	2.162e-48	174.0	COG1761@1|root,arCOG04111@2157|Archaea,41SV9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	RNA polymerase Rpb3/Rpb11 dimerisation domain	-	-	2.7.7.6	ko:K03056	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_L_2
DYD2_k127_6516534_0	1229909.NSED_01805	0.0	1407.0	COG0013@1|root,arCOG01255@2157|Archaea,41SBJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DYD2_k127_6516534_1	436308.Nmar_0367	0.0	1392.0	COG0495@1|root,arCOG00809@2157|Archaea,41SES@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
DYD2_k127_6516534_4	436308.Nmar_1696	3.873e-74	254.0	COG0778@1|root,arCOG00288@2157|Archaea	2157|Archaea	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DYD2_k127_6516534_2	1229909.NSED_01730	4.874e-194	607.0	COG0644@1|root,arCOG00570@2157|Archaea,41SCG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
DYD2_k127_6516534_3	1229909.NSED_01720	2.189e-134	429.0	COG0727@1|root,arCOG02579@2157|Archaea,41SH8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DYD2_k127_6516534_5	1229909.NSED_01715	9.412e-52	184.0	arCOG10523@1|root,arCOG10523@2157|Archaea,41SSZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6532396_6	436308.Nmar_1482	8.095e-134	428.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DYD2_k127_6532396_9	1229909.NSED_08160	1.485e-71	245.0	arCOG08637@1|root,arCOG08637@2157|Archaea,41SV0@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6532396_4	1229909.NSED_08155	4.174e-180	567.0	COG0214@1|root,arCOG04075@2157|Archaea,41SEJ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the PdxS SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
DYD2_k127_6532396_7	1229909.NSED_08150	2.701e-88	295.0	COG0311@1|root,arCOG00034@2157|Archaea,41SIZ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
DYD2_k127_6532396_17	1229909.NSED_01025	3.475e-13	81.0	COG1340@1|root,arCOG08038@1|root,arCOG01159@2157|Archaea,arCOG08038@2157|Archaea	2157|Archaea	S	protein secretion by the type IV secretion system	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
DYD2_k127_6532396_16	1131266.ARWQ01000029_gene982	1.484e-31	132.0	arCOG08793@1|root,arCOG08793@2157|Archaea,41TBC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6532396_0	1229909.NSED_08040	0.0	1437.0	COG0525@1|root,arCOG00808@2157|Archaea,41SBK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Anticodon-binding domain of tRNA	-	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DYD2_k127_6532396_5	1229909.NSED_08035	7.718e-159	503.0	COG0720@1|root,arCOG02172@2157|Archaea,41SY8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DYD2_k127_6532396_12	1229909.NSED_08030	2.627e-48	173.0	COG2154@1|root,arCOG02939@2157|Archaea,41SSQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
DYD2_k127_6532396_10	1459636.NTE_00858	1.12e-65	233.0	COG0367@1|root,arCOG00071@2157|Archaea,41SIX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
DYD2_k127_6532396_2	1229909.NSED_08020	9.756e-256	793.0	COG0015@1|root,arCOG01747@2157|Archaea,41SD1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	adenylosuccinate lyase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
DYD2_k127_6532396_1	1229909.NSED_07985	1.396e-290	895.0	COG1690@1|root,arCOG04246@2157|Archaea,41SE4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
DYD2_k127_6532396_11	436308.Nmar_1452	4.575e-52	186.0	arCOG05529@1|root,arCOG05529@2157|Archaea,41SSJ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	dsDNA_bind
DYD2_k127_6532396_13	1229909.NSED_07975	2.626e-42	156.0	arCOG08729@1|root,arCOG08729@2157|Archaea,41T8R@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6532396_8	1229909.NSED_07970	4.064e-80	269.0	COG0100@1|root,arCOG04240@2157|Archaea,41SII@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located on the platform of the 30S subunit	rps11	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DYD2_k127_6532396_15	1229909.NSED_07965	6.647e-33	131.0	arCOG11453@1|root,arCOG11453@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6532396_14	374847.Kcr_0043	3.099e-41	164.0	COG0611@1|root,arCOG00638@2157|Archaea	2157|Archaea	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DYD2_k127_6532396_3	1229909.NSED_07955	1.375e-224	703.0	COG1109@1|root,arCOG00767@2157|Archaea,41SC1@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DYD2_k127_6541845_1	1229909.NSED_01215	1.885e-243	758.0	COG0165@1|root,arCOG01748@2157|Archaea,41S6A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
DYD2_k127_6541845_5	436308.Nmar_0262	9.643e-62	213.0	COG2151@1|root,arCOG01845@2157|Archaea,41SQV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DYD2_k127_6541845_2	436308.Nmar_0261	2.541e-148	470.0	COG0479@1|root,arCOG00962@2157|Archaea,41SAW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
DYD2_k127_6541845_6	1229909.NSED_01200	6.367e-55	194.0	COG2142@1|root,arCOG04162@2157|Archaea,41SRA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
DYD2_k127_6541845_4	436308.Nmar_0259	2.071e-78	263.0	COG2009@1|root,arCOG02244@2157|Archaea,41SKZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
DYD2_k127_6541845_0	1229909.NSED_01190	0.0	1065.0	COG1053@1|root,arCOG00571@2157|Archaea,41SAM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	fumarate reductase flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DYD2_k127_6541845_3	1229909.NSED_01185	1.674e-87	291.0	COG1695@1|root,arCOG00002@2157|Archaea,41SN8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
DYD2_k127_6541845_7	436308.Nmar_0256	2.126e-22	96.0	COG2513@1|root,arCOG00581@2157|Archaea,41SEN@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
DYD2_k127_6570125_1	1229909.NSED_00130	4.696e-90	301.0	COG0468@1|root,arCOG00417@2157|Archaea,41SQC@651137|Thaumarchaeota	651137|Thaumarchaeota	T	RecA RadA	-	-	-	ko:K04482,ko:K04483	ko03440,ko03460,ko05200,ko05212,map03440,map03460,map05200,map05212	-	-	-	ko00000,ko00001,ko03400,ko04121,ko04131	-	-	-	Rad51
DYD2_k127_6570125_0	436308.Nmar_0088	3.245e-258	801.0	COG1201@1|root,arCOG00557@2157|Archaea,41S8P@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DYD2_k127_659847_6	1229909.NSED_02655	1.764e-32	126.0	COG1278@1|root,arCOG02983@2157|Archaea,41T9B@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DYD2_k127_659847_5	1229909.NSED_02650	1.499e-62	216.0	COG0361@1|root,arCOG01179@2157|Archaea,41SRK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	-	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
DYD2_k127_659847_4	436308.Nmar_0525	1.445e-93	309.0	COG0727@1|root,arCOG02579@2157|Archaea,41T3E@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
DYD2_k127_659847_7	351160.RRC47	1.237e-09	66.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_11,HTH_24
DYD2_k127_659847_2	1229909.NSED_02635	2.547e-106	349.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
DYD2_k127_659847_0	1229909.NSED_02630	3.087e-195	613.0	COG1064@1|root,arCOG01455@2157|Archaea,41SA9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DYD2_k127_659847_1	1229909.NSED_02625	1.094e-116	378.0	COG1354@1|root,arCOG02610@2157|Archaea,41SMU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	-
DYD2_k127_659847_3	436308.Nmar_0521	2.849e-94	311.0	COG1386@1|root,arCOG02613@2157|Archaea,41SIC@651137|Thaumarchaeota	651137|Thaumarchaeota	K	segregation and condensation protein	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
DYD2_k127_6687785_8	1229909.NSED_04715	3.906e-16	80.0	28HMW@1|root,2N5MZ@2157|Archaea,41T97@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6687785_3	436308.Nmar_0858	6.499e-77	261.0	COG2096@1|root,arCOG00489@2157|Archaea,41T2I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
DYD2_k127_6687785_4	1229909.NSED_04730	5.522e-64	224.0	COG1896@1|root,arCOG04311@2157|Archaea,41SQE@651137|Thaumarchaeota	651137|Thaumarchaeota	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
DYD2_k127_6687785_7	1229909.NSED_04735	4.102e-25	106.0	arCOG10554@1|root,arCOG10554@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6687785_6	436308.Nmar_0861	3.065e-37	142.0	arCOG10555@1|root,arCOG10555@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6687785_5	1229909.NSED_04745	1.301e-53	190.0	arCOG08655@1|root,arCOG08655@2157|Archaea,41SR9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6687785_0	1229909.NSED_04750	1.196e-236	734.0	COG1915@1|root,arCOG04422@2157|Archaea,41SBQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
DYD2_k127_6687785_2	1229909.NSED_04755	1.465e-130	419.0	COG0467@1|root,arCOG01171@2157|Archaea,41TA0@651137|Thaumarchaeota	651137|Thaumarchaeota	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
DYD2_k127_6687785_1	1229909.NSED_04760	4.414e-156	495.0	COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
DYD2_k127_6725108_0	436308.Nmar_1219	2.145e-76	269.0	COG0582@1|root,arCOG01241@2157|Archaea	2157|Archaea	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	ssrA	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
DYD2_k127_681408_0	1229909.NSED_08165	0.0	1338.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DYD2_k127_681408_1	1229909.NSED_08170	2.443e-125	402.0	arCOG08638@1|root,arCOG08638@2157|Archaea,41T08@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_681408_2	1229909.NSED_08175	8.464e-92	304.0	arCOG08639@1|root,arCOG08639@2157|Archaea,41SP8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_681408_3	1229909.NSED_08180	1.45e-25	105.0	COG1522@1|root,arCOG01117@2157|Archaea,41ST7@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
DYD2_k127_724309_1	1229909.NSED_02140	6.065e-164	522.0	COG1052@1|root,arCOG01755@2157|Archaea,41T1D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DYD2_k127_724309_3	1229909.NSED_02135	7.068e-44	163.0	arCOG08665@1|root,arCOG08665@2157|Archaea	2157|Archaea	S	Haem utilisation ChuX/HutX	-	-	-	-	-	-	-	-	-	-	-	-	ChuX_HutX
DYD2_k127_724309_4	1229909.NSED_02130	7.065e-38	143.0	arCOG08666@1|root,arCOG08666@2157|Archaea,41SVR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_724309_0	436308.Nmar_0409	2.728e-230	718.0	COG0579@1|root,arCOG00754@2157|Archaea,41SXA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
DYD2_k127_724309_2	1229909.NSED_09750	7.782e-55	193.0	COG3945@1|root,arCOG01471@2157|Archaea,41T45@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
DYD2_k127_819341_5	1343739.PAP_01830	3.832e-18	87.0	COG5253@1|root,arCOG04169@2157|Archaea,2XT9A@28890|Euryarchaeota,243XV@183968|Thermococci	183968|Thermococci	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
DYD2_k127_819341_3	1229909.NSED_01950	3.455e-85	285.0	COG2019@1|root,arCOG01039@2157|Archaea,41SK7@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the archaeal adenylate kinase family	adkA	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
DYD2_k127_819341_1	436308.Nmar_0404	4.091e-97	321.0	COG1422@1|root,arCOG02673@2157|Archaea,41SNR@651137|Thaumarchaeota	651137|Thaumarchaeota	U	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF106
DYD2_k127_819341_2	436308.Nmar_0405	5.45e-94	311.0	COG1102@1|root,arCOG01037@2157|Archaea,41SKS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DYD2_k127_819341_0	1229909.NSED_01965	6.139e-194	607.0	COG0130@1|root,arCOG00987@2157|Archaea,41S8E@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs	truB	-	-	ko:K11131	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03032	-	-	-	DKCLD,PUA,TruB_C_2,TruB_N
DYD2_k127_819341_4	1229909.NSED_01970	6.352e-54	192.0	arCOG07571@1|root,arCOG07571@2157|Archaea,41T4H@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_856901_2	436308.Nmar_0700	4.458e-67	233.0	arCOG04054@1|root,arCOG04054@2157|Archaea,41SIQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_856901_0	436308.Nmar_0701	0.0	1122.0	COG0365@1|root,arCOG04201@2157|Archaea	2157|Archaea	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DYD2_k127_856901_1	436308.Nmar_0702	3.533e-84	281.0	arCOG06712@1|root,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9
DYD2_k127_856901_4	436308.Nmar_0365	1.095e-27	114.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_856901_3	436308.Nmar_0703	2.15e-63	219.0	COG0258@1|root,arCOG04050@2157|Archaea,41SBU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
DYD2_k127_857792_6	1229909.NSED_01230	1.074e-20	91.0	COG5466@1|root,arCOG05278@2157|Archaea,41T8X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
DYD2_k127_857792_3	1229909.NSED_01235	2.358e-150	478.0	COG1018@1|root,arCOG02200@2157|Archaea,41S72@651137|Thaumarchaeota	651137|Thaumarchaeota	C	oxidoreductase FAD NAD(P)-binding	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
DYD2_k127_857792_4	436308.Nmar_0268	1.269e-139	447.0	COG0483@1|root,arCOG01349@2157|Archaea,41SIF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DYD2_k127_857792_2	1229909.NSED_01245	1.954e-205	642.0	arCOG08783@1|root,arCOG08783@2157|Archaea,41SFX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_857792_1	1229909.NSED_01250	1.771e-214	669.0	COG0470@1|root,arCOG00470@2157|Archaea,41S9F@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA
DYD2_k127_857792_5	1229909.NSED_01255	5.904e-53	187.0	arCOG08784@1|root,arCOG08784@2157|Archaea,41SVZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_857792_0	1229909.NSED_01260	2.733e-310	952.0	COG4799@1|root,arCOG02705@2157|Archaea,41SEH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18604	ko00720,ko01120,map00720,map01120	-	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
DYD2_k127_880423_5	1229909.NSED_07815	1.962e-48	174.0	arCOG08771@1|root,arCOG08771@2157|Archaea,41SNZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_880423_7	436308.Nmar_1426	2.45e-46	169.0	COG3432@1|root,arCOG01055@2157|Archaea,41SUJ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
DYD2_k127_880423_4	436308.Nmar_1427	4.242e-81	274.0	COG0009@1|root,arCOG01952@2157|Archaea,41SPF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Sua5 YciO YrdC YwlC family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
DYD2_k127_880423_6	1131266.ARWQ01000018_gene768	1.032e-47	176.0	COG1818@1|root,arCOG00084@2157|Archaea,41SNW@651137|Thaumarchaeota	651137|Thaumarchaeota	S	THUMP domain	-	-	-	ko:K06963	-	-	-	-	ko00000,ko03016	-	-	-	THUMP
DYD2_k127_880423_2	436308.Nmar_1429	1.327e-104	345.0	COG1617@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG02197@2157|Archaea,41SSW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Kinase binding protein CGI-121	-	-	-	-	-	-	-	-	-	-	-	-	CGI-121,ThiS
DYD2_k127_880423_11	1229909.NSED_07840	3.51e-27	114.0	COG1383@1|root,arCOG01885@2157|Archaea,41SUH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
DYD2_k127_880423_1	436308.Nmar_1431	3.654e-124	402.0	COG0084@1|root,arCOG00891@2157|Archaea,41SGP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DYD2_k127_880423_10	436308.Nmar_1432	1.796e-30	121.0	COG2036@1|root,arCOG02144@2157|Archaea,41T91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	transcription factor (CBF NF-Y)	-	-	-	-	-	-	-	-	-	-	-	-	CBFD_NFYB_HMF
DYD2_k127_880423_9	1229909.NSED_07855	4.473e-43	161.0	COG3794@1|root,arCOG02926@2157|Archaea,41TAN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
DYD2_k127_880423_0	1229909.NSED_07860	0.0	1075.0	arCOG06613@1|root,arCOG06613@2157|Archaea,41T0Z@651137|Thaumarchaeota	651137|Thaumarchaeota	V	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
DYD2_k127_880423_12	1229909.NSED_07865	2.285e-21	94.0	arCOG08678@1|root,arCOG08678@2157|Archaea,41TA6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_880423_3	1229909.NSED_07870	1.358e-95	316.0	arCOG08730@1|root,arCOG08730@2157|Archaea,41SNH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_880423_8	436308.Nmar_1446	8.189e-46	166.0	COG3432@1|root,arCOG01055@2157|Archaea,41SST@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
DYD2_k127_880423_14	1229909.NSED_07880	1.217e-17	84.0	arCOG11531@1|root,arCOG11531@2157|Archaea,41TAQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_880423_13	1131266.ARWQ01000001_gene1078	4.582e-18	85.0	arCOG10410@1|root,arCOG10410@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_885247_1	1229909.NSED_01675	4.241e-157	496.0	COG0086@1|root,arCOG04256@2157|Archaea,arCOG04257@2157|Archaea,41SB2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	-	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
DYD2_k127_885247_0	1229909.NSED_01670	0.0	2190.0	COG0085@1|root,arCOG01762@2157|Archaea,41SF5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
DYD2_k127_885247_2	1229909.NSED_01665	7.421e-48	171.0	COG2012@1|root,arCOG04258@2157|Archaea,41SU8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoH	-	2.7.7.6	ko:K03053	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb5_C
DYD2_k127_921596_1	436308.Nmar_1031	2.69e-74	251.0	arCOG08678@1|root,arCOG08678@2157|Archaea,41SR1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_921596_4	1229909.NSED_06075	1.649e-28	117.0	arCOG10406@1|root,arCOG10406@2157|Archaea,41SVU@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zinc finger, C2H2 type	-	-	-	-	-	-	-	-	-	-	-	-	zf-C2H2
DYD2_k127_921596_3	436308.Nmar_1032	3.292e-34	131.0	COG1996@1|root,arCOG04341@2157|Archaea,41SWH@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	-
DYD2_k127_921596_2	1229909.NSED_06085	6.075e-59	204.0	COG0051@1|root,arCOG01758@2157|Archaea,41SQB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in the binding of tRNA to the ribosomes	rps10	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
DYD2_k127_921596_0	1229909.NSED_06090	1.187e-210	655.0	COG5256@1|root,arCOG01561@2157|Archaea,41SD2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DYD2_k127_980800_1	710696.Intca_0489	1.274e-97	332.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4FIKZ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
DYD2_k127_980800_6	1229909.NSED_06785	1.191e-24	105.0	arCOG08692@1|root,arCOG08692@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_980800_0	436308.Nmar_1191	0.0	1189.0	COG1331@1|root,arCOG02007@2157|Archaea,41SHZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
DYD2_k127_980800_3	1229909.NSED_06775	6.578e-51	182.0	arCOG08080@1|root,arCOG08080@2157|Archaea,41SUA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_980800_4	1229909.NSED_06770	3.491e-48	174.0	arCOG08691@1|root,arCOG08691@2157|Archaea,41T93@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_980800_2	436308.Nmar_1187	1.763e-62	217.0	arCOG08690@1|root,arCOG08690@2157|Archaea,41T98@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_980800_5	436308.Nmar_1185	4.643e-47	174.0	arCOG08689@1|root,arCOG08689@2157|Archaea,41T5U@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_980800_7	1229909.NSED_06755	3.621e-13	69.0	arCOG08688@1|root,arCOG08688@2157|Archaea,41T55@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 1310 queries scanned
## Total time (seconds): 5.123420000076294
## Rate: 255.69 q/s