## Sun Mar 16 14:54:53 2025
## emapper-2.1.9
## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD2_bin.63.fa -m mmseqs --itype genome -o DYD2_bin.63 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD2_bin.63 --cpu 8
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
DYD2_k127_1017309_0	861299.J421_3128	2.602e-159	512.0	COG0192@1|root,COG0192@2|Bacteria,1ZSZ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
DYD2_k127_1017309_1	1444309.JAQG01000016_gene683	3.304e-117	400.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,26QD5@186822|Paenibacillaceae	91061|Bacilli	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
DYD2_k127_1017309_2	478741.JAFS01000002_gene704	3.184e-23	104.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia,37GYW@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	PTS HPr component phosphorylation site	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
DYD2_k127_1019289_0	861299.J421_4174	1.874e-191	615.0	COG1132@1|root,COG1132@2|Bacteria,1ZSP1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
DYD2_k127_1019289_2	1267534.KB906756_gene339	4.126e-21	101.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
DYD2_k127_1019289_1	426114.THI_2504	7.357e-32	136.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VHDQ@28216|Betaproteobacteria,1KPEY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Response_reg
DYD2_k127_1084660_3	861299.J421_3350	3.307e-44	169.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
DYD2_k127_1084660_0	861299.J421_3349	7.289e-236	742.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DYD2_k127_1084660_7	1121861.KB899920_gene2926	5.585e-08	65.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2UHNB@28211|Alphaproteobacteria,2JUGI@204441|Rhodospirillales	204441|Rhodospirillales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DYD2_k127_1084660_4	479434.Sthe_2173	2.635e-37	150.0	COG0350@1|root,COG5662@1|root,COG0350@2|Bacteria,COG5662@2|Bacteria,2G98B@200795|Chloroflexi,27Z9T@189775|Thermomicrobia	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	cseE	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	zf-HC2
DYD2_k127_1084660_6	479434.Sthe_2174	2.181e-16	93.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_1084660_2	861299.J421_3347	3.278e-58	205.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
DYD2_k127_1084660_1	379066.GAU_1707	1.266e-229	738.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
DYD2_k127_1084660_5	379066.GAU_1706	6.298e-37	147.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
DYD2_k127_1103071_0	32049.SYNPCC7002_A0984	1.174e-161	521.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1GZ6W@1129|Synechococcus	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
DYD2_k127_1103071_2	197221.22294416	8.739e-34	133.0	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria	1117|Cyanobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
DYD2_k127_1103071_1	1173025.GEI7407_3430	1.761e-108	366.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
DYD2_k127_1103071_3	585501.HMPREF6123_0997	1.757e-21	96.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,2PSQJ@265975|Oribacterium	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DYD2_k127_1109466_1	861299.J421_2943	1.154e-59	218.0	COG1234@1|root,COG1234@2|Bacteria,1ZT5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DYD2_k127_1109466_0	1379270.AUXF01000005_gene505	1.417e-99	347.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DYD2_k127_1111856_1	234267.Acid_7336	1.784e-52	202.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
DYD2_k127_1111856_0	861299.J421_2172	1.531e-73	253.0	COG0400@1|root,COG0400@2|Bacteria,1ZTXT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
DYD2_k127_1111856_2	502025.Hoch_2362	2.243e-34	148.0	COG0457@1|root,COG0515@1|root,COG2114@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2114@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
DYD2_k127_1136490_0	886293.Sinac_0383	2.167e-86	300.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DYD2_k127_1136490_1	926550.CLDAP_19100	7.574e-15	79.0	COG0181@1|root,COG0181@2|Bacteria,2G6JU@200795|Chloroflexi	200795|Chloroflexi	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
DYD2_k127_1137121_0	1121405.dsmv_0256	2.657e-92	312.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DYD2_k127_1137121_1	448385.sce6263	4.96e-49	188.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
DYD2_k127_1140104_1	1379698.RBG1_1C00001G0322	2.309e-47	186.0	COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria	2|Bacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
DYD2_k127_1140104_0	1089548.KI783301_gene1899	1.458e-149	486.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,3WFAP@539002|Bacillales incertae sedis	91061|Bacilli	H	intramolecular transferase activity, transferring amino groups	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS08395	Aminotran_3
DYD2_k127_1140375_1	861299.J421_3271	1.085e-45	175.0	COG0331@1|root,COG0331@2|Bacteria,1ZT40@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
DYD2_k127_1140375_0	498761.HM1_2161	1.461e-86	299.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
DYD2_k127_1140375_2	469383.Cwoe_3692	4.152e-09	58.0	COG0333@1|root,COG0333@2|Bacteria,2HPDQ@201174|Actinobacteria,4CQRN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
DYD2_k127_1152880_1	861299.J421_3133	5.652e-58	213.0	COG1120@1|root,COG1120@2|Bacteria,1ZTB9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
DYD2_k127_1152880_0	379066.GAU_0496	3.427e-76	267.0	COG0609@1|root,COG0609@2|Bacteria,1ZTAA@142182|Gemmatimonadetes	2|Bacteria	P	FecCD transport family	btuC	-	3.6.3.34	ko:K02013,ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	FecCD
DYD2_k127_1158412_2	1219031.BBJR01000042_gene2874	0.0008867	52.0	COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,2VKM8@28216|Betaproteobacteria,4ACJG@80864|Comamonadaceae	28216|Betaproteobacteria	V	TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD	cydD	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
DYD2_k127_1158412_0	251221.35214577	8.279e-135	461.0	COG0249@1|root,COG0249@2|Bacteria	2|Bacteria	L	mismatched DNA binding	mutS1	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_III,MutS_V
DYD2_k127_1158412_1	483219.LILAB_09920	3.308e-19	96.0	COG0558@1|root,COG0558@2|Bacteria,1P9BV@1224|Proteobacteria,432CD@68525|delta/epsilon subdivisions,2WX7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
DYD2_k127_1168838_1	1521187.JPIM01000003_gene2972	1.372e-146	489.0	COG0843@1|root,COG0843@2|Bacteria,2G628@200795|Chloroflexi,37691@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DYD2_k127_1168838_3	1118054.CAGW01000050_gene1222	7.034e-42	162.0	COG1622@1|root,COG1622@2|Bacteria,1TPMD@1239|Firmicutes,4HGXU@91061|Bacilli,26XKH@186822|Paenibacillaceae	91061|Bacilli	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
DYD2_k127_1168838_5	926550.CLDAP_07190	3.177e-35	153.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
DYD2_k127_1168838_4	1304883.KI912532_gene2095	6.597e-38	164.0	COG1131@1|root,COG1131@2|Bacteria,1MXHE@1224|Proteobacteria,2VN8A@28216|Betaproteobacteria,2KVJR@206389|Rhodocyclales	206389|Rhodocyclales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD2_k127_1168838_2	518766.Rmar_2014	2.653e-87	320.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1FJC4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Domain present in carbohydrate binding proteins and sugar hydrolses	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
DYD2_k127_1168838_6	1123325.JHUV01000008_gene743	6.76e-32	134.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
DYD2_k127_1168838_0	518766.Rmar_2012	5.724e-287	892.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1FIVE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DYD2_k127_1177031_1	518766.Rmar_1819	4.05e-92	312.0	COG0501@1|root,COG0501@2|Bacteria,4PEI7@976|Bacteroidetes,1FJ5Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
DYD2_k127_1177031_0	861299.J421_2339	2.927e-115	417.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	2|Bacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
DYD2_k127_1177031_2	1123023.JIAI01000004_gene8204	2.24e-70	274.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
DYD2_k127_121284_1	1125863.JAFN01000001_gene2584	2.589e-108	371.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DYD2_k127_121284_0	1379270.AUXF01000003_gene3408	2.142e-174	561.0	COG1220@1|root,COG1220@2|Bacteria,1ZSVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
DYD2_k127_121284_3	861299.J421_3964	1.232e-73	253.0	COG5405@1|root,COG5405@2|Bacteria,1ZSVH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
DYD2_k127_121284_2	861299.J421_3967	8.38e-82	283.0	COG4974@1|root,COG4974@2|Bacteria,1ZT3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DYD2_k127_1216948_4	886293.Sinac_1233	3.066e-48	181.0	COG0720@1|root,COG0720@2|Bacteria,2IZMP@203682|Planctomycetes	203682|Planctomycetes	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
DYD2_k127_1216948_3	1380390.JIAT01000010_gene4323	1.663e-71	257.0	COG1767@1|root,COG1767@2|Bacteria,2H80Q@201174|Actinobacteria,4CTM7@84995|Rubrobacteria	84995|Rubrobacteria	H	ATP:dephospho-CoA triphosphoribosyl transferase	-	-	2.4.2.52	ko:K05966	ko02020,map02020	-	R09675	RC00049,RC00063	ko00000,ko00001,ko01000	-	-	-	CitG
DYD2_k127_1216948_2	1380390.JIAT01000010_gene4336	2.464e-79	288.0	COG0189@1|root,COG0189@2|Bacteria,2HXBM@201174|Actinobacteria	201174|Actinobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.43	ko:K05827,ko:K05844	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RimK,TrkA_C
DYD2_k127_1216948_0	1380390.JIAT01000010_gene4329	1.231e-103	346.0	COG3252@1|root,COG3252@2|Bacteria	2|Bacteria	H	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT	mch	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704	3.5.4.27	ko:K01499	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03464	RC01870	ko00000,ko00001,ko00002,ko01000	-	-	-	MCH
DYD2_k127_1216948_1	1304874.JAFY01000002_gene389	1.267e-79	271.0	COG2037@1|root,COG2037@2|Bacteria,3TC31@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)	-	-	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
DYD2_k127_1260365_1	926569.ANT_05700	1.901e-65	230.0	COG2080@1|root,COG2080@2|Bacteria,2G8E9@200795|Chloroflexi	200795|Chloroflexi	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
DYD2_k127_1260365_0	196490.AUEZ01000042_gene7227	1.725e-138	451.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DYD2_k127_1268808_1	309801.trd_1894	2.223e-31	133.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi,27Y4R@189775|Thermomicrobia	189775|Thermomicrobia	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_1268808_2	469383.Cwoe_2923	2.318e-11	77.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1268808_0	1379270.AUXF01000006_gene290	1.64e-179	582.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
DYD2_k127_1274493_1	869210.Marky_0675	1.128e-35	154.0	COG0128@1|root,COG0128@2|Bacteria,1WI9P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
DYD2_k127_1274493_0	1192034.CAP_3975	8.028e-102	342.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,42VTH@68525|delta/epsilon subdivisions,2WS84@28221|Deltaproteobacteria,2YYDW@29|Myxococcales	28221|Deltaproteobacteria	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
DYD2_k127_1294115_1	1379698.RBG1_1C00001G1858	2.749e-68	256.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
DYD2_k127_1294115_0	861299.J421_3479	5.408e-117	401.0	COG1596@1|root,COG1596@2|Bacteria,1ZUC0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
DYD2_k127_1296382_0	379066.GAU_0009	5.39e-56	216.0	2DTII@1|root,33KI8@2|Bacteria,1ZT3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1302553_2	379066.GAU_2585	2.115e-19	98.0	2C9AX@1|root,33WUH@2|Bacteria,1ZTQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1302553_1	1170562.Cal6303_4700	8.441e-56	209.0	COG0053@1|root,COG0053@2|Bacteria,1G0RT@1117|Cyanobacteria,1HJJE@1161|Nostocales	1117|Cyanobacteria	U	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
DYD2_k127_1302553_0	861299.J421_4196	2.423e-314	976.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
DYD2_k127_1308907_2	1379270.AUXF01000006_gene174	1.184e-23	106.0	COG0173@1|root,COG0173@2|Bacteria,1ZTFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DYD2_k127_1308907_1	1142394.PSMK_13590	8.306e-25	120.0	COG1762@1|root,COG1762@2|Bacteria,2IZ73@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
DYD2_k127_1308907_0	1382356.JQMP01000003_gene1710	7.414e-76	270.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,27XRH@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
DYD2_k127_1315246_1	861299.J421_4375	3.924e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_1315246_6	1379270.AUXF01000001_gene2633	8.556e-06	57.0	2F756@1|root,33ZKP@2|Bacteria,1ZU38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1315246_5	1123236.KB899386_gene1849	2.09e-12	78.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,466GU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
DYD2_k127_1315246_2	1379270.AUXF01000001_gene2631	2.252e-46	178.0	COG3595@1|root,COG3595@2|Bacteria,1ZTQ0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
DYD2_k127_1315246_0	1128421.JAGA01000003_gene3380	1.732e-112	375.0	COG3437@1|root,COG3437@2|Bacteria,2NPBP@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
DYD2_k127_1315246_4	861299.J421_0442	1.039e-29	129.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_1315246_3	671143.DAMO_0102	6.758e-42	175.0	COG4772@1|root,COG4772@2|Bacteria,2NRIP@2323|unclassified Bacteria	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
DYD2_k127_1319242_1	234267.Acid_2187	1.835e-51	189.0	COG0019@1|root,COG0019@2|Bacteria,3Y2W4@57723|Acidobacteria	57723|Acidobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DYD2_k127_1319242_0	861299.J421_2748	0.0	1282.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DYD2_k127_1335961_1	428125.CLOLEP_03305	1.428e-10	75.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3WG8U@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
DYD2_k127_1335961_0	1125863.JAFN01000001_gene1108	1.195e-38	148.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WMFY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DYD2_k127_1337203_0	379066.GAU_1168	3.246e-109	357.0	COG1012@1|root,COG1012@2|Bacteria,1ZST9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
DYD2_k127_1337203_3	861299.J421_2921	7.185e-78	269.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
DYD2_k127_1337203_2	861299.J421_2922	1.416e-90	317.0	COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DYD2_k127_1337203_4	373903.Hore_02460	1.667e-55	199.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WAPJ@53433|Halanaerobiales	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
DYD2_k127_1337203_5	1433126.BN938_2361	1.444e-33	143.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia,22UI2@171550|Rikenellaceae	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
DYD2_k127_1337203_1	1379270.AUXF01000006_gene119	2.904e-97	330.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
DYD2_k127_1337203_6	272568.GDI3018	1.003e-26	116.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,2JQWM@204441|Rhodospirillales	204441|Rhodospirillales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DYD2_k127_1339171_7	575540.Isop_3054	8.039e-05	50.0	COG1807@1|root,COG1807@2|Bacteria,2J1H1@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DYD2_k127_1339171_3	1379698.RBG1_1C00001G1315	2.456e-67	262.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DYD2_k127_1339171_0	861299.J421_3250	1.541e-188	602.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
DYD2_k127_1339171_1	861299.J421_3251	8.701e-102	355.0	COG1137@1|root,COG1137@2|Bacteria,1ZT4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
DYD2_k127_1339171_5	379066.GAU_1619	1.387e-24	121.0	2F01D@1|root,33T57@2|Bacteria,1ZTGK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1339171_6	861299.J421_3253	2.098e-15	90.0	2DWX3@1|root,342B9@2|Bacteria,1ZTXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
DYD2_k127_1339171_2	671143.DAMO_0273	3.148e-98	340.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,2NNNB@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	2.5.1.55,5.3.1.13	ko:K01627,ko:K03281,ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530,R03254	RC00435,RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	2.A.49	-	iAF987.Gmet_1278	CBS,SIS
DYD2_k127_1339171_4	861299.J421_3255	3.657e-37	147.0	COG1778@1|root,COG1778@2|Bacteria,1ZTTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
DYD2_k127_1341416_0	290397.Adeh_1417	5.583e-220	702.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD2_k127_1341416_1	195250.CM001776_gene1399	2.638e-15	86.0	COG5305@1|root,COG5305@2|Bacteria,1G2NQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DYD2_k127_1353310_7	379066.GAU_1975	1.244e-53	191.0	COG0100@1|root,COG0100@2|Bacteria,1ZTMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
DYD2_k127_1353310_5	861299.J421_3577	3.169e-84	286.0	COG0522@1|root,COG0522@2|Bacteria,1ZTGJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
DYD2_k127_1353310_3	861299.J421_3576	3.652e-97	329.0	COG0202@1|root,COG0202@2|Bacteria,1ZTEV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
DYD2_k127_1353310_9	861299.J421_3575	2.521e-35	140.0	COG0203@1|root,COG0203@2|Bacteria,1ZTPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
DYD2_k127_1353310_10	1121403.AUCV01000008_gene1556	1.038e-16	81.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MKZY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
DYD2_k127_1353310_8	266117.Rxyl_1977	1.368e-50	192.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
DYD2_k127_1353310_2	264732.Moth_1246	1.329e-116	399.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
DYD2_k127_1353310_6	357808.RoseRS_1853	2.504e-56	215.0	COG1089@1|root,COG1089@2|Bacteria,2G6AN@200795|Chloroflexi,3755V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DYD2_k127_1353310_0	1120999.JONM01000003_gene2692	7.125e-163	533.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,2KQTE@206351|Neisseriales	206351|Neisseriales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DYD2_k127_1353310_1	861299.J421_0145	1.018e-148	480.0	COG0451@1|root,COG0451@2|Bacteria,1ZUJJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DYD2_k127_1353310_4	1173029.JH980292_gene1765	7.364e-93	317.0	COG1215@1|root,COG1215@2|Bacteria,1GHF8@1117|Cyanobacteria,1H7FV@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD2_k127_1363346_0	861299.J421_2940	7.976e-115	391.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
DYD2_k127_1363346_2	1379698.RBG1_1C00001G0865	7.812e-16	83.0	COG0776@1|root,COG0776@2|Bacteria,2NPTH@2323|unclassified Bacteria	2|Bacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530,ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DYD2_k127_1363346_1	1121015.N789_09300	8.595e-40	152.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
DYD2_k127_1370233_1	379066.GAU_2477	9.431e-94	312.0	COG0473@1|root,COG0473@2|Bacteria,1ZTDX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DYD2_k127_1370233_0	861299.J421_3934	7.229e-183	584.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD2_k127_1370233_2	298654.FraEuI1c_0484	6.113e-39	162.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4EU0N@85013|Frankiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	lpqC	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
DYD2_k127_1370233_5	1379698.RBG1_1C00001G1696	1.89e-06	50.0	COG0590@1|root,COG0590@2|Bacteria,2NPM7@2323|unclassified Bacteria	2|Bacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
DYD2_k127_1370233_3	391593.RCCS2_09204	1.267e-19	95.0	COG3238@1|root,COG3238@2|Bacteria	2|Bacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
DYD2_k127_1370233_4	489825.LYNGBM3L_05860	2.159e-16	89.0	COG4424@1|root,COG4424@2|Bacteria,1G29K@1117|Cyanobacteria,1HAQB@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
DYD2_k127_1373705_0	1297742.A176_01664	8.893e-55	213.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YW82@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
DYD2_k127_1373705_1	861299.J421_2606	5.688e-44	175.0	COG2094@1|root,COG2094@2|Bacteria,1ZTNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
DYD2_k127_1385660_0	379066.GAU_0010	4.303e-180	582.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DYD2_k127_1385660_6	1379270.AUXF01000002_gene1621	4.539e-54	214.0	2EWAK@1|root,33PPB@2|Bacteria,1ZT00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1385660_7	118163.Ple7327_4428	5.881e-28	118.0	2BG65@1|root,32A2Y@2|Bacteria,1G6VZ@1117|Cyanobacteria,3VJZ3@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1385660_1	861299.J421_3775	6.783e-104	381.0	COG1078@1|root,COG1078@2|Bacteria,1ZT3F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
DYD2_k127_1385660_5	861299.J421_3777	1.368e-61	220.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
DYD2_k127_1385660_2	379066.GAU_0710	2.136e-92	313.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DYD2_k127_1385660_3	379066.GAU_0921	7.89e-84	290.0	COG0123@1|root,COG0123@2|Bacteria,1ZSKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DYD2_k127_1385660_4	1379270.AUXF01000001_gene2809	4.095e-81	290.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
DYD2_k127_1407431_1	1157640.AQWO01000015_gene1197	2.792e-78	276.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria	201174|Actinobacteria	E	ornithine cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
DYD2_k127_1407431_0	584708.Apau_0710	3.567e-100	340.0	COG3275@1|root,COG4191@1|root,COG3275@2|Bacteria,COG4191@2|Bacteria,3TBCP@508458|Synergistetes	508458|Synergistetes	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DYD2_k127_1414846_2	338963.Pcar_2697	0.0001049	53.0	2ER9F@1|root,33IV2@2|Bacteria,1P4XJ@1224|Proteobacteria,433CC@68525|delta/epsilon subdivisions,2WXNX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1414846_1	1382304.JNIL01000001_gene540	4.717e-42	179.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,278D5@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
DYD2_k127_1414846_0	861299.J421_0066	7.879e-281	889.0	COG0567@1|root,COG0567@2|Bacteria,1ZSVR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
DYD2_k127_1431224_1	1246448.ANAZ01000008_gene2411	7.668e-43	172.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DYD2_k127_1431224_0	246197.MXAN_3119	1.016e-75	269.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,42P6V@68525|delta/epsilon subdivisions,2WM6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
DYD2_k127_1431224_2	1288079.AUKN01000002_gene5612	9.613e-42	164.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
DYD2_k127_1433164_2	861299.J421_0621	2.391e-61	224.0	2AI77@1|root,318MJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1433164_0	861299.J421_0622	5.921e-239	748.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
DYD2_k127_1433164_4	861299.J421_0625	5.868e-49	182.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
DYD2_k127_1433164_6	335283.Neut_2211	1.331e-22	115.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2VIBH@28216|Betaproteobacteria,373P5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
DYD2_k127_1433164_3	861299.J421_2914	2.116e-60	235.0	COG1606@1|root,COG1606@2|Bacteria	2|Bacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
DYD2_k127_1433164_5	1121468.AUBR01000066_gene914	9.404e-28	121.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,42H6P@68295|Thermoanaerobacterales	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
DYD2_k127_1433164_1	861299.J421_2920	4.64e-168	536.0	COG1012@1|root,COG1012@2|Bacteria,1ZST9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
DYD2_k127_1456445_1	1298593.TOL_1718	4.803e-53	201.0	COG2960@1|root,COG2960@2|Bacteria,1NJYD@1224|Proteobacteria,1RYI7@1236|Gammaproteobacteria,1XNAU@135619|Oceanospirillales	135619|Oceanospirillales	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1456445_4	523791.Kkor_1288	2.239e-27	120.0	COG2010@1|root,COG2010@2|Bacteria,1RFJV@1224|Proteobacteria,1S4GY@1236|Gammaproteobacteria,1XPKF@135619|Oceanospirillales	135619|Oceanospirillales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
DYD2_k127_1456445_6	368407.Memar_1352	0.0002274	44.0	COG2217@1|root,arCOG01576@2157|Archaea,2XT3T@28890|Euryarchaeota,2N99E@224756|Methanomicrobia	224756|Methanomicrobia	P	haloacid dehalogenase-like hydrolase	copB	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
DYD2_k127_1456445_5	309807.SRU_2822	6.154e-16	87.0	COG2968@1|root,COG2968@2|Bacteria,4P8H6@976|Bacteroidetes,1FJN4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DYD2_k127_1456445_2	1384056.N787_11655	1.428e-52	196.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1X4HM@135614|Xanthomonadales	135614|Xanthomonadales	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
DYD2_k127_1456445_0	453591.Igni_0773	3.372e-80	284.0	COG0107@1|root,arCOG00617@2157|Archaea,2XQ5E@28889|Crenarchaeota	28889|Crenarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DYD2_k127_1456445_3	1122919.KB905623_gene154	1.079e-30	128.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,26SVR@186822|Paenibacillaceae	91061|Bacilli	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DYD2_k127_1477773_3	136993.KB900626_gene2581	3.598e-30	125.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2UBP8@28211|Alphaproteobacteria,37053@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Haem-degrading	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
DYD2_k127_1477773_5	221288.JH992901_gene4739	2.488e-20	99.0	COG1359@1|root,COG1359@2|Bacteria,1GAAJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
DYD2_k127_1477773_2	316058.RPB_4677	1.286e-68	243.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,3JR7C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	MA20_22790	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
DYD2_k127_1477773_1	1396418.BATQ01000016_gene4273	2.091e-78	276.0	COG0697@1|root,COG0697@2|Bacteria,46T3I@74201|Verrucomicrobia,2IVMP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD2_k127_1477773_4	309807.SRU_1893	2.107e-29	133.0	2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
DYD2_k127_1477773_0	861299.J421_3000	7.789e-152	496.0	COG0183@1|root,COG0183@2|Bacteria,1ZTGX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD2_k127_1479164_1	945713.IALB_2034	2.704e-170	551.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
DYD2_k127_1479164_0	518766.Rmar_1178	6.461e-214	688.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1FJT8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DYD2_k127_1483718_1	379066.GAU_1926	1.529e-84	304.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
DYD2_k127_1483718_2	1125863.JAFN01000001_gene2274	2.622e-45	177.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
DYD2_k127_1483718_3	1379698.RBG1_1C00001G1748	3.765e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,2NS1B@2323|unclassified Bacteria	2|Bacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1483718_0	1379270.AUXF01000006_gene30	4.353e-97	355.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
DYD2_k127_1492555_0	1192034.CAP_4888	9.287e-170	546.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DYD2_k127_1498904_2	401053.AciPR4_3009	1.124e-08	63.0	COG4980@1|root,COG4980@2|Bacteria,3Y5IA@57723|Acidobacteria,2JK01@204432|Acidobacteriia	204432|Acidobacteriia	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
DYD2_k127_1498904_1	861299.J421_2878	3.239e-25	118.0	COG1295@1|root,COG1295@2|Bacteria,1ZTHX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
DYD2_k127_1498904_0	591158.SSMG_00942	4.007e-38	159.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
DYD2_k127_1512177_7	290315.Clim_1144	7.186e-54	212.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
DYD2_k127_1512177_1	379066.GAU_1390	8.039e-168	546.0	COG0004@1|root,COG0004@2|Bacteria,1ZT74@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
DYD2_k127_1512177_8	861299.J421_6292	7.882e-51	183.0	COG0347@1|root,COG0347@2|Bacteria,1ZTTV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
DYD2_k127_1512177_6	1223523.H340_07718	5.196e-61	220.0	COG3246@1|root,COG3246@2|Bacteria,2GMMZ@201174|Actinobacteria	201174|Actinobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
DYD2_k127_1512177_0	1396141.BATP01000001_gene5393	1.263e-238	752.0	COG1866@1|root,COG1866@2|Bacteria,46TRA@74201|Verrucomicrobia,2IVD3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Phosphoenolpyruvate carboxykinase	-	-	-	-	-	-	-	-	-	-	-	-	PEPCK_ATP
DYD2_k127_1512177_4	234267.Acid_1836	2.063e-76	287.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria	57723|Acidobacteria	E	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
DYD2_k127_1512177_3	1192034.CAP_4260	3.274e-79	293.0	COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
DYD2_k127_1512177_5	649747.HMPREF0083_02331	2.172e-75	263.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HAX6@91061|Bacilli,26TFE@186822|Paenibacillaceae	91061|Bacilli	P	Superoxide dismutase	sodF	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF2935,Sod_Fe_C,Sod_Fe_N
DYD2_k127_1512177_2	357808.RoseRS_1829	1.188e-134	439.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
DYD2_k127_1512177_9	1192034.CAP_5445	1.052e-47	180.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2WZ2N@28221|Deltaproteobacteria,2Z16Z@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
DYD2_k127_1512177_11	945713.IALB_1991	3.897e-20	104.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
DYD2_k127_1512177_10	861299.J421_4450	5.181e-22	98.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DYD2_k127_1536755_10	1173021.ALWA01000027_gene2631	1.547e-13	70.0	2EK6X@1|root,33DXA@2|Bacteria,1GFHH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1536755_6	498761.HM1_3148	7.22e-29	117.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1536755_4	1382230.ASAP_2763	1.939e-37	148.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1536755_1	1329516.JPST01000014_gene611	1.792e-128	423.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,27BBQ@186824|Thermoactinomycetaceae	91061|Bacilli	J	Protein of unknown function (DUF933)	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
DYD2_k127_1536755_5	1173025.GEI7407_2882	5.237e-30	126.0	COG2314@1|root,COG2314@2|Bacteria,1G8AE@1117|Cyanobacteria,1HBGS@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
DYD2_k127_1536755_7	530564.Psta_2193	2.399e-25	121.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	MA20_31615	-	-	-	-	-	-	-	-	-	-	-	CBS
DYD2_k127_1536755_2	861299.J421_3680	7.407e-73	255.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
DYD2_k127_1536755_3	391625.PPSIR1_03918	4.185e-67	246.0	COG2503@1|root,COG2503@2|Bacteria,1RB4N@1224|Proteobacteria,42UJS@68525|delta/epsilon subdivisions,2WVMM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
DYD2_k127_1536755_8	1379270.AUXF01000002_gene1695	7.117e-23	116.0	COG1871@1|root,COG1871@2|Bacteria,1ZTR7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
DYD2_k127_1536755_0	518766.Rmar_1990	4.269e-134	434.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
DYD2_k127_1550105_0	861299.J421_2757	3.478e-127	433.0	COG0215@1|root,COG0215@2|Bacteria,1ZT77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
DYD2_k127_1550105_1	1303518.CCALI_00599	3.502e-14	72.0	COG0050@1|root,COG0050@2|Bacteria	2|Bacteria	J	translation elongation factor activity	tuf	GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484	-	ko:K02358,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
DYD2_k127_1587764_6	379066.GAU_2199	1.32e-40	162.0	COG1629@1|root,COG4771@2|Bacteria,1ZUQM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
DYD2_k127_1587764_3	1121920.AUAU01000014_gene2814	1.36e-115	386.0	COG1816@1|root,COG1816@2|Bacteria,3Y2R0@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
DYD2_k127_1587764_4	861299.J421_3838	1.088e-78	291.0	COG0737@1|root,COG0737@2|Bacteria,1ZTEA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
DYD2_k127_1587764_0	639282.DEFDS_0235	0.0	1054.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GF76@200930|Deferribacteres	200930|Deferribacteres	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
DYD2_k127_1587764_2	1232410.KI421413_gene539	7.567e-152	525.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43RZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Glutamine amidotransferases class-II	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
DYD2_k127_1587764_1	861299.J421_3380	2.425e-263	841.0	COG0046@1|root,COG0046@2|Bacteria,1ZT8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DYD2_k127_1587764_5	518766.Rmar_2306	3.059e-73	252.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DYD2_k127_1588968_1	290397.Adeh_2440	5.027e-101	338.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
DYD2_k127_1588968_0	1089550.ATTH01000001_gene359	2.873e-137	464.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,1FJQG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
DYD2_k127_1588968_2	926550.CLDAP_36650	2.977e-48	190.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
DYD2_k127_1588968_3	861299.J421_1172	6.273e-35	140.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DYD2_k127_1622494_0	379066.GAU_1477	9.537e-121	398.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
DYD2_k127_1622494_4	1379698.RBG1_1C00001G0554	6.845e-05	52.0	COG2893@1|root,COG2893@2|Bacteria,2NRZU@2323|unclassified Bacteria	2|Bacteria	G	system, fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
DYD2_k127_1622494_1	1379270.AUXF01000005_gene732	6.395e-36	143.0	COG3444@1|root,COG3444@2|Bacteria,1ZTQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system sorbose subfamily IIB component	-	-	-	ko:K19507	ko02060,map02060	M00764	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.19	-	-	PTSIIB_sorb
DYD2_k127_1622494_3	861299.J421_3124	1.315e-17	92.0	COG3715@1|root,COG3715@2|Bacteria,1ZTVH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
DYD2_k127_1622494_2	861299.J421_3125	1.209e-34	149.0	COG3716@1|root,COG3716@2|Bacteria,1ZTJH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
DYD2_k127_1634383_3	997884.HMPREF1068_01983	3.504e-31	134.0	COG1596@1|root,COG1596@2|Bacteria,4NEXJ@976|Bacteroidetes,2FM4E@200643|Bacteroidia,4ANHT@815|Bacteroidaceae	976|Bacteroidetes	M	COG1596 Periplasmic protein involved in polysaccharide export	kpsD	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
DYD2_k127_1634383_2	379066.GAU_2419	1.822e-96	327.0	COG0859@1|root,COG0859@2|Bacteria,1ZT3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DYD2_k127_1634383_0	379066.GAU_0638	1.258e-155	530.0	COG0745@1|root,COG0745@2|Bacteria,1ZTEW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
DYD2_k127_1634383_1	379066.GAU_0639	2.885e-154	516.0	COG1132@1|root,COG1132@2|Bacteria,1ZT2T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
DYD2_k127_1634383_4	123899.JPQP01000004_gene347	4.614e-27	123.0	COG0478@1|root,COG0478@2|Bacteria,1QUI1@1224|Proteobacteria,2WGVZ@28216|Betaproteobacteria,3T3Y2@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
DYD2_k127_1669191_0	385682.AFSL01000009_gene2466	1.834e-115	384.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,2FM8Y@200643|Bacteroidia,3XJAC@558415|Marinilabiliaceae	976|Bacteroidetes	C	L-lysine 6-monooxygenase (NADPH-requiring)	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
DYD2_k127_1669191_3	861299.J421_2661	1.742e-51	205.0	COG0321@1|root,COG0321@2|Bacteria,1ZTM1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
DYD2_k127_1669191_4	300852.55771716	9.58e-39	148.0	COG1993@1|root,COG1993@2|Bacteria,1WKB2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
DYD2_k127_1669191_5	861299.J421_2335	1.361e-26	119.0	COG0239@1|root,COG0239@2|Bacteria,1ZU3U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
DYD2_k127_1669191_2	379066.GAU_0829	5.691e-69	241.0	COG1760@1|root,COG1760@2|Bacteria,1ZTFS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Serine dehydratase beta chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
DYD2_k127_1669191_1	861299.J421_2752	6.627e-78	282.0	COG1760@1|root,COG1760@2|Bacteria,1ZT3U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
DYD2_k127_1681570_0	861299.J421_0329	5.666e-116	404.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
DYD2_k127_1687839_0	1463934.JOCF01000009_gene4698	1.339e-96	326.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
DYD2_k127_1687839_1	1906.SFRA_05190	1.536e-49	196.0	COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine	egtA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
DYD2_k127_1687839_2	378806.STAUR_6430	6.684e-46	181.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DYD2_k127_169508_0	661478.OP10G_2752	1.286e-128	425.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
DYD2_k127_169508_1	861299.J421_1883	2.778e-45	179.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	2|Bacteria	K	Sigma-70, region 4	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_175860_0	309807.SRU_0893	4.357e-23	115.0	COG2982@1|root,COG2982@2|Bacteria,4PF1Z@976|Bacteroidetes,1FK0M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
DYD2_k127_1782958_4	1379698.RBG1_1C00001G1062	6.281e-79	274.0	COG1007@1|root,COG1007@2|Bacteria,2NNMY@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN-1	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
DYD2_k127_1782958_3	1123371.ATXH01000009_gene1104	5.795e-137	454.0	COG1109@1|root,COG1109@2|Bacteria,2GHQ7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DYD2_k127_1782958_2	1089553.Tph_c00600	1.586e-137	470.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,42FMF@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
DYD2_k127_1782958_5	880073.Calab_0632	1.799e-70	261.0	COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria	2|Bacteria	E	Amino acid kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452	AA_kinase
DYD2_k127_1782958_0	861299.J421_3279	4.18e-140	454.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
DYD2_k127_1782958_1	861299.J421_3278	6.378e-138	444.0	COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
DYD2_k127_1782958_6	1121918.ARWE01000001_gene1208	2.173e-05	48.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,43SGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	NDK	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
DYD2_k127_1793593_2	547559.Nmag_2897	9.373e-74	260.0	COG1024@1|root,arCOG00239@2157|Archaea,2XTF0@28890|Euryarchaeota,23SMM@183963|Halobacteria	183963|Halobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD2_k127_1793593_6	485913.Krac_9650	2.287e-05	56.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
DYD2_k127_1793593_3	867903.ThesuDRAFT_00659	8.691e-32	128.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3WCME@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
DYD2_k127_1793593_4	926559.JoomaDRAFT_1699	3.082e-27	118.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,4NSHE@976|Bacteroidetes,1HYAI@117743|Flavobacteriia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
DYD2_k127_1793593_1	867903.ThesuDRAFT_00656	2.253e-122	412.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
DYD2_k127_1793593_0	861299.J421_3340	6.902e-149	484.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD2_k127_1793593_5	861299.J421_4365	1.68e-05	51.0	2EY2H@1|root,33RBE@2|Bacteria,1ZTHK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1822314_3	234267.Acid_5757	5.038e-25	119.0	COG1595@1|root,COG1595@2|Bacteria,3Y8YQ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1822314_1	861299.J421_5669	7.544e-42	169.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
DYD2_k127_1822314_0	1261545.MBE-HAL_2182	4.799e-61	229.0	COG0819@1|root,arCOG01128@2157|Archaea,2XTG7@28890|Euryarchaeota,23STS@183963|Halobacteria	183963|Halobacteria	K	transcription activator	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
DYD2_k127_1822314_2	479435.Kfla_6656	6.959e-26	117.0	COG0819@1|root,COG0819@2|Bacteria,2IGXQ@201174|Actinobacteria	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)	-	-	-	ko:K20896	ko00730,ko01100,map00730,map01100	-	R09993,R11313	RC00197,RC02832	ko00000,ko00001,ko01000	-	-	-	TENA_THI-4
DYD2_k127_1912895_1	1380394.JADL01000009_gene3137	4.22e-133	431.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2TVQ7@28211|Alphaproteobacteria,2JW2G@204441|Rhodospirillales	204441|Rhodospirillales	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	HpaB,HpaB_N
DYD2_k127_1912895_3	426114.THI_3126	1.087e-119	399.0	COG0642@1|root,COG0642@2|Bacteria,1PA1G@1224|Proteobacteria,2VHX5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
DYD2_k127_1912895_9	1236501.BAJU01000026_gene2326	7.166e-69	241.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2JP8N@204441|Rhodospirillales	204441|Rhodospirillales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
DYD2_k127_1912895_5	379066.GAU_2447	5.261e-106	364.0	COG0534@1|root,COG0534@2|Bacteria,1ZTFM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
DYD2_k127_1912895_13	861299.J421_3913	1.284e-59	218.0	COG1912@1|root,COG1912@2|Bacteria,1ZTIH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
DYD2_k127_1912895_14	861299.J421_3911	1.202e-40	163.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
DYD2_k127_1912895_16	861299.J421_3910	2.026e-14	87.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DYD2_k127_1912895_17	861299.J421_3909	9.266e-07	59.0	2F9A9@1|root,341MC@2|Bacteria,1ZU0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_1912895_11	861299.J421_3908	7.013e-62	221.0	COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_1912895_2	1379270.AUXF01000003_gene3486	4.752e-132	430.0	COG0043@1|root,COG0043@2|Bacteria,1ZSMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DYD2_k127_1912895_7	861299.J421_3906	1.924e-84	281.0	COG0043@1|root,COG0043@2|Bacteria,1ZSMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
DYD2_k127_1912895_8	861299.J421_3905	4.036e-76	279.0	COG0382@1|root,COG0382@2|Bacteria,1ZT35@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
DYD2_k127_1912895_10	861299.J421_3904	1.595e-67	251.0	COG0163@1|root,COG0163@2|Bacteria,1ZTIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
DYD2_k127_1912895_15	379066.GAU_2436	5.607e-32	134.0	COG0622@1|root,COG0622@2|Bacteria,1ZTSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
DYD2_k127_1912895_12	402881.Plav_3659	5.739e-61	222.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,1JN96@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
DYD2_k127_1912895_4	1121430.JMLG01000005_gene779	2.228e-112	383.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
DYD2_k127_1912895_6	1121904.ARBP01000003_gene6376	5.091e-85	293.0	COG0501@1|root,COG0501@2|Bacteria,4NT8D@976|Bacteroidetes,47RHS@768503|Cytophagia	976|Bacteroidetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,zf-ribbon_3
DYD2_k127_1912895_0	861299.J421_3896	3.439e-140	456.0	COG0626@1|root,COG0626@2|Bacteria,1ZT9F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
DYD2_k127_1915553_2	290397.Adeh_2253	8.505e-80	284.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
DYD2_k127_1915553_8	118168.MC7420_1583	2.35e-13	79.0	COG1357@1|root,COG1357@2|Bacteria,1G5FM@1117|Cyanobacteria,1HA7H@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
DYD2_k127_1915553_7	1254432.SCE1572_21390	1.107e-13	81.0	COG1357@1|root,COG1357@2|Bacteria,1RB3M@1224|Proteobacteria,43APP@68525|delta/epsilon subdivisions,2X63D@28221|Deltaproteobacteria,2Z0TZ@29|Myxococcales	28221|Deltaproteobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
DYD2_k127_1915553_5	485913.Krac_9874	3.425e-28	119.0	COG3059@1|root,COG3059@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
DYD2_k127_1915553_1	886293.Sinac_5868	8.301e-97	330.0	COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
DYD2_k127_1915553_3	861299.J421_3884	5.313e-48	180.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_1915553_0	861299.J421_1876	5.693e-219	700.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
DYD2_k127_1915553_4	861299.J421_1875	3.541e-42	159.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
DYD2_k127_1919664_1	880073.Calab_0511	2.347e-44	169.0	COG4221@1|root,COG4221@2|Bacteria,2NPJV@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
DYD2_k127_1919664_0	1120950.KB892739_gene3944	7.846e-70	251.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4DNRC@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	fprD	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
DYD2_k127_192079_0	379066.GAU_2152	1.052e-271	862.0	COG0481@1|root,COG0481@2|Bacteria,1ZTGT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,LepA_C
DYD2_k127_192079_1	1379270.AUXF01000005_gene378	2.349e-72	258.0	COG1235@1|root,COG1235@2|Bacteria,1ZT49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
DYD2_k127_192079_2	861299.J421_2871	2.556e-29	121.0	COG0469@1|root,COG0469@2|Bacteria,1ZSMD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
DYD2_k127_1956513_1	479434.Sthe_0894	6.195e-42	171.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,27Z1J@189775|Thermomicrobia	189775|Thermomicrobia	M	Tetratricopeptide repeat	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
DYD2_k127_1956513_2	1042163.BRLA_c012500	5.911e-25	105.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,26YYQ@186822|Paenibacillaceae	91061|Bacilli	K	Cold-shock protein	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DYD2_k127_1956513_0	861299.J421_1151	6.514e-97	325.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DYD2_k127_1972915_1	1379270.AUXF01000005_gene588	1.159e-25	122.0	COG2372@1|root,COG2372@2|Bacteria,1ZTUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
DYD2_k127_1972915_0	867903.ThesuDRAFT_00642	5.619e-206	660.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WCDF@538999|Clostridiales incertae sedis	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
DYD2_k127_1992935_5	1379270.AUXF01000006_gene275	3.913e-18	95.0	COG0392@1|root,COG0392@2|Bacteria,1ZTX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DYD2_k127_1992935_1	1379270.AUXF01000006_gene276	6.402e-82	293.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
DYD2_k127_1992935_4	66429.JOFL01000005_gene3723	3.704e-47	176.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
DYD2_k127_1992935_3	1433126.BN938_1386	2.143e-49	195.0	COG1238@1|root,COG1238@2|Bacteria,4PIJW@976|Bacteroidetes,2G1VB@200643|Bacteroidia,22V72@171550|Rikenellaceae	976|Bacteroidetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DYD2_k127_1992935_2	861299.J421_3240	8.741e-58	218.0	COG2518@1|root,COG2518@2|Bacteria,1ZTED@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DYD2_k127_1992935_0	379066.GAU_1605	1.541e-88	298.0	COG0496@1|root,COG0496@2|Bacteria,1ZT6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
DYD2_k127_1997697_1	457570.Nther_1346	1.057e-39	160.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia	186801|Clostridia	T	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
DYD2_k127_1997697_2	56780.SYN_01339	4.663e-26	113.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2MQM6@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
DYD2_k127_1997697_0	861299.J421_2948	2.882e-78	271.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
DYD2_k127_2004289_1	1415775.U729_2730	7.733e-06	55.0	29V2B@1|root,30GFG@2|Bacteria,1UFXY@1239|Firmicutes,24KMA@186801|Clostridia,36JHR@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2004289_0	861299.J421_3571	0.0	1502.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
DYD2_k127_2006838_2	880072.Desac_2878	5.069e-94	317.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
DYD2_k127_2006838_1	378806.STAUR_5446	1.078e-104	348.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,2YTUG@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K12371,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00324,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
DYD2_k127_2006838_4	861299.J421_2680	6.335e-12	66.0	COG0444@1|root,COG0444@2|Bacteria,1ZSWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
DYD2_k127_2006838_0	1379270.AUXF01000004_gene3121	3.774e-109	363.0	COG4608@1|root,COG4608@2|Bacteria,1ZSTB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
DYD2_k127_2006838_3	1191523.MROS_2571	6.121e-42	164.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
DYD2_k127_201185_1	1379270.AUXF01000001_gene2437	3.525e-68	237.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
DYD2_k127_201185_3	861299.J421_0468	1.617e-09	61.0	COG0515@1|root,COG0515@2|Bacteria,1ZUHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DYD2_k127_201185_0	886293.Sinac_2843	1.289e-222	728.0	COG1680@1|root,COG2173@1|root,COG1680@2|Bacteria,COG2173@2|Bacteria,2IWSU@203682|Planctomycetes	203682|Planctomycetes	MV	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Peptidase_M15
DYD2_k127_201185_2	861299.J421_1261	1.03e-65	235.0	COG0612@1|root,COG0612@2|Bacteria,1ZT7N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16_C
DYD2_k127_2016271_3	1036674.A28LD_0671	2.6e-34	142.0	2DPEU@1|root,331SS@2|Bacteria,1NDKB@1224|Proteobacteria,1RTE7@1236|Gammaproteobacteria,2QG29@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
DYD2_k127_2016271_2	350688.Clos_0620	4.512e-36	145.0	COG0073@1|root,COG0073@2|Bacteria,1V6N9@1239|Firmicutes,24JJZ@186801|Clostridia,36K08@31979|Clostridiaceae	186801|Clostridia	J	PFAM t-RNA-binding domain protein	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
DYD2_k127_2016271_1	471852.Tcur_1018	3.547e-56	208.0	COG0463@1|root,COG0463@2|Bacteria,2GYYN@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Branch
DYD2_k127_2016271_0	861299.J421_1489	3.448e-153	491.0	COG1013@1|root,COG1013@2|Bacteria,1ZSWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DYD2_k127_2022703_5	284031.JNXD01000017_gene7034	3.995e-05	50.0	COG0457@1|root,COG0457@2|Bacteria,2GJD3@201174|Actinobacteria	201174|Actinobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
DYD2_k127_2022703_3	861299.J421_1280	1.967e-19	104.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
DYD2_k127_2022703_4	1235279.C772_01261	1.166e-05	59.0	2CICC@1|root,32S7S@2|Bacteria,1VC46@1239|Firmicutes,4HKPJ@91061|Bacilli,26FSV@186818|Planococcaceae	91061|Bacilli	-	-	yneQ	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2022703_0	861299.J421_1368	2.089e-121	404.0	COG0312@1|root,COG0312@2|Bacteria,1ZSYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
DYD2_k127_2022703_2	861299.J421_0527	5.954e-76	276.0	COG0312@1|root,COG0312@2|Bacteria,1ZSWE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DYD2_k127_2022703_1	1379270.AUXF01000002_gene1210	8.007e-82	276.0	COG0312@1|root,COG0312@2|Bacteria,1ZSWE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
DYD2_k127_20564_2	1051501.AYTL01000027_gene1293	1.793e-07	59.0	COG1266@1|root,COG1266@2|Bacteria,1VHVC@1239|Firmicutes,4HPR7@91061|Bacilli,1ZIRG@1386|Bacillus	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
DYD2_k127_20564_1	309807.SRU_0806	4.618e-16	92.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
DYD2_k127_20564_0	518766.Rmar_2461	3.475e-19	90.0	COG0477@1|root,COG2814@2|Bacteria,4PI8A@976|Bacteroidetes,1FJNM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DYD2_k127_2070050_1	1382304.JNIL01000001_gene645	6.411e-56	213.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,2783K@186823|Alicyclobacillaceae	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
DYD2_k127_2070050_0	861299.J421_3084	1.943e-109	377.0	COG1200@1|root,COG1200@2|Bacteria,1ZT3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DYD2_k127_2072906_3	1094980.Mpsy_2614	4.576e-96	320.0	COG1331@1|root,arCOG02007@2157|Archaea,2XU5Q@28890|Euryarchaeota,2N91Y@224756|Methanomicrobia	224756|Methanomicrobia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
DYD2_k127_2072906_2	1254432.SCE1572_02795	2.036e-105	374.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
DYD2_k127_2072906_8	861299.J421_2968	1.749e-42	177.0	COG1947@1|root,COG1947@2|Bacteria,1ZTM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
DYD2_k127_2072906_7	861299.J421_2969	1.206e-60	229.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
DYD2_k127_2072906_5	321332.CYB_0455	6.296e-82	279.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria,1GZKF@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
DYD2_k127_2072906_9	1121396.KB893091_gene3485	4.106e-21	105.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,42PJR@68525|delta/epsilon subdivisions,2WPBQ@28221|Deltaproteobacteria,2MI0V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
DYD2_k127_2072906_1	861299.J421_3506	7.536e-125	421.0	COG2262@1|root,COG2262@2|Bacteria,1ZSYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
DYD2_k127_2072906_0	861299.J421_3508	2.854e-153	497.0	COG2256@1|root,COG2256@2|Bacteria,1ZTCA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
DYD2_k127_2072906_4	861299.J421_3513	8.14e-91	315.0	COG0617@1|root,COG0617@2|Bacteria,1ZSKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
DYD2_k127_2072906_6	379066.GAU_1912	6.395e-67	239.0	COG1028@1|root,COG1028@2|Bacteria,1ZTJK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DYD2_k127_2098428_1	861299.J421_3563	1.846e-131	428.0	COG0317@1|root,COG0317@2|Bacteria,1ZT5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
DYD2_k127_2098428_0	379066.GAU_1953	1.36e-277	876.0	COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
DYD2_k127_2098428_9	760568.Desku_0546	8.817e-20	106.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
DYD2_k127_2098428_10	1111454.HMPREF1250_0086	2.814e-19	101.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4H47Z@909932|Negativicutes	909932|Negativicutes	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
DYD2_k127_2098428_6	379066.GAU_1949	1.453e-30	126.0	COG0454@1|root,COG0456@2|Bacteria,1ZU09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
DYD2_k127_2098428_5	1121104.AQXH01000002_gene663	3.634e-41	157.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1ISJD@117747|Sphingobacteriia	976|Bacteroidetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
DYD2_k127_2098428_11	502025.Hoch_0501	1.792e-14	87.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2YVFR@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
DYD2_k127_2098428_12	522772.Dacet_2906	2.762e-08	64.0	COG0755@1|root,COG0755@2|Bacteria,2GFK2@200930|Deferribacteres	200930|Deferribacteres	O	Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
DYD2_k127_2098428_3	644966.Tmar_1263	3.169e-90	314.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
DYD2_k127_2098428_2	1089553.Tph_c03640	2.854e-97	332.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,42F1C@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
DYD2_k127_2098428_4	861299.J421_3554	2.966e-50	190.0	COG0811@1|root,COG0811@2|Bacteria,1ZTBF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
DYD2_k127_2098428_8	379066.GAU_1944	5.364e-26	116.0	COG0848@1|root,COG0848@2|Bacteria,1ZTRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
DYD2_k127_2098428_7	861299.J421_3552	4.887e-26	116.0	COG0810@1|root,COG0810@2|Bacteria,1ZTWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
DYD2_k127_2106351_1	861299.J421_1210	1.657e-126	419.0	28JRE@1|root,2Z9H3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2106351_4	420324.KI912082_gene6903	4.009e-26	126.0	COG2730@1|root,COG2730@2|Bacteria,1QU12@1224|Proteobacteria	1224|Proteobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_2,Calx-beta,Cellulase
DYD2_k127_2106351_2	1265313.HRUBRA_01348	7.436e-88	313.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
DYD2_k127_2106351_0	861299.J421_3780	0.0	1065.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
DYD2_k127_2106351_3	443143.GM18_3530	5.037e-50	206.0	COG1215@1|root,COG2344@1|root,COG1215@2|Bacteria,COG2344@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,43S6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD2_k127_2140180_1	445972.ANACOL_03422	2.818e-101	340.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
DYD2_k127_2140180_0	404589.Anae109_1884	1.493e-101	347.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
DYD2_k127_218081_0	1379698.RBG1_1C00001G0312	7.9e-182	591.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
DYD2_k127_218081_4	861299.J421_2623	5.957e-10	70.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD,OmpA
DYD2_k127_218081_3	292459.STH819	9.556e-38	162.0	COG1427@1|root,COG1427@2|Bacteria,1V2PX@1239|Firmicutes,24CGN@186801|Clostridia	186801|Clostridia	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
DYD2_k127_218081_2	379066.GAU_3855	6.554e-74	258.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DYD2_k127_218081_1	1379270.AUXF01000004_gene3177	3.81e-81	280.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DYD2_k127_22168_12	448385.sce7198	1.14e-05	52.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria,2YV9A@29|Myxococcales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
DYD2_k127_22168_7	861299.J421_2520	3.683e-51	199.0	COG0354@1|root,COG0354@2|Bacteria,1ZTMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
DYD2_k127_22168_5	1267533.KB906740_gene330	7.51e-73	260.0	COG1071@1|root,COG1071@2|Bacteria,3Y4M3@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
DYD2_k127_22168_2	861299.J421_3597	1.212e-120	415.0	COG0022@1|root,COG0022@2|Bacteria,1ZT89@142182|Gemmatimonadetes	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DYD2_k127_22168_4	861299.J421_3595	1.776e-109	377.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
DYD2_k127_22168_9	1121468.AUBR01000096_gene781	2.676e-15	88.0	2AII4@1|root,31902@2|Bacteria,1VY3B@1239|Firmicutes,251KQ@186801|Clostridia,42IFA@68295|Thermoanaerobacterales	186801|Clostridia	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_22168_3	379066.GAU_0146	2.916e-117	401.0	COG5276@1|root,COG5492@1|root,COG5276@2|Bacteria,COG5492@2|Bacteria,1ZU8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD2_k127_22168_6	744872.Spica_1978	2.467e-71	249.0	COG0428@1|root,COG0428@2|Bacteria,2J6TD@203691|Spirochaetes	203691|Spirochaetes	P	PFAM zinc iron permease	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
DYD2_k127_22168_1	518766.Rmar_1177	3.632e-174	592.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1FJQ4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein	-	-	2.5.1.48,4.4.1.1,4.4.1.11	ko:K01739,ko:K01758,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
DYD2_k127_22168_0	861299.J421_1696	1.228e-207	673.0	COG2866@1|root,COG2866@2|Bacteria,1ZUNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
DYD2_k127_22168_10	263358.VAB18032_18195	2.298e-09	64.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
DYD2_k127_2222486_1	1122611.KB903990_gene7226	4.494e-39	166.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
DYD2_k127_2222486_0	861299.J421_2838	1.142e-79	289.0	COG2103@1|root,COG2103@2|Bacteria,1ZT2A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
DYD2_k127_223179_0	861299.J421_3223	2.015e-91	323.0	COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DYD2_k127_223179_1	1125863.JAFN01000001_gene3412	5.506e-82	282.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
DYD2_k127_223179_2	861299.J421_3221	0.0001651	44.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
DYD2_k127_2242915_0	644966.Tmar_1189	1.329e-191	611.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,3WCD1@538999|Clostridiales incertae sedis	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
DYD2_k127_2242915_1	1243664.CAVL020000005_gene264	8.347e-52	188.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,4HBM0@91061|Bacilli,1ZBI0@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0173 family	ytkL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
DYD2_k127_2252356_0	1379270.AUXF01000001_gene2615	6.986e-206	655.0	COG0587@1|root,COG0587@2|Bacteria,1ZU9R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
DYD2_k127_2256847_2	861299.J421_3883	1.923e-71	244.0	COG1429@1|root,COG1429@2|Bacteria	2|Bacteria	H	ligase activity, forming nitrogen-metal bonds	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,Glyco_hydro_63
DYD2_k127_2256847_0	1496688.ER33_11555	7.405e-262	824.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
DYD2_k127_2256847_1	861299.J421_1879	1.38e-141	479.0	COG1252@1|root,COG1252@2|Bacteria,1ZT8C@142182|Gemmatimonadetes	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_2261405_4	702113.PP1Y_AT10952	2.531e-05	54.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2UHNB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DYD2_k127_2261405_0	880073.Calab_3349	2.067e-140	469.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_3349|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2261405_3	227377.CBU_1821	5.659e-35	139.0	COG4453@1|root,COG4453@2|Bacteria	2|Bacteria	K	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
DYD2_k127_2261405_2	227377.CBU_1820	5.491e-60	213.0	2BHMV@1|root,32BQM@2|Bacteria,1N9I1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2261405_1	379066.GAU_0094	1.491e-80	299.0	COG0515@1|root,COG0515@2|Bacteria,1ZUHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DYD2_k127_2272527_1	243231.GSU2041	7.057e-136	447.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U83@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
DYD2_k127_2272527_2	243231.GSU2042	7.774e-63	235.0	COG4191@1|root,COG4191@2|Bacteria,1R9AK@1224|Proteobacteria,42Q2G@68525|delta/epsilon subdivisions,2WM8Y@28221|Deltaproteobacteria,43RXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DYD2_k127_2272527_0	1379270.AUXF01000002_gene1477	1.724e-178	569.0	COG0174@1|root,COG0174@2|Bacteria,1ZSYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
DYD2_k127_2275367_3	641524.ADICYQ_1354	9.719e-15	87.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47NKR@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
DYD2_k127_2275367_1	378806.STAUR_4874	1.217e-93	319.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DYD2_k127_2275367_0	404589.Anae109_0064	2.962e-143	465.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2Z30V@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD2_k127_2275367_2	56780.SYN_02180	9.272e-92	312.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2MQ9P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DYD2_k127_2278975_1	868864.Dester_0952	1.19e-10	63.0	COG0490@1|root,COG0490@2|Bacteria,2G45Z@200783|Aquificae	200783|Aquificae	P	TrkA-C domain protein	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
DYD2_k127_2278975_0	243233.MCA2576	4.307e-253	801.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1XEFY@135618|Methylococcales	1236|Gammaproteobacteria	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_8,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
DYD2_k127_2294610_2	926560.KE387023_gene2058	5.188e-25	111.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
DYD2_k127_2294610_1	471853.Bcav_0979	4.02e-48	184.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
DYD2_k127_2294610_0	1379270.AUXF01000004_gene2955	1.137e-63	229.0	COG0860@1|root,COG0860@2|Bacteria,1ZT6J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
DYD2_k127_2299836_1	1232410.KI421413_gene700	4.352e-57	226.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TZX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
DYD2_k127_2299836_0	379066.GAU_1177	3.146e-66	244.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DYD2_k127_2305651_0	861299.J421_0339	5.631e-220	702.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
DYD2_k127_2305651_1	1379270.AUXF01000007_gene997	4.202e-87	292.0	COG2819@1|root,COG2819@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
DYD2_k127_2311478_0	861299.J421_2604	2.929e-86	297.0	COG0318@1|root,COG0318@2|Bacteria,1ZSXP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
DYD2_k127_2311478_1	667014.Thein_0957	1.579e-72	262.0	COG0337@1|root,COG0337@2|Bacteria,2GGYX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
DYD2_k127_2343162_3	573370.DMR_22950	7.601e-13	79.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WRC7@28221|Deltaproteobacteria,2M821@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_3,TetR_N
DYD2_k127_2343162_1	886293.Sinac_3443	2.444e-60	215.0	COG0225@1|root,COG0225@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
DYD2_k127_2343162_0	861299.J421_2577	6.67e-142	469.0	COG0436@1|root,COG0436@2|Bacteria,1ZT26@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
DYD2_k127_2343162_2	404589.Anae109_4231	9.889e-45	169.0	arCOG07238@1|root,34BTI@2|Bacteria,1P13S@1224|Proteobacteria,4354M@68525|delta/epsilon subdivisions,2WZFN@28221|Deltaproteobacteria,2Z21A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2345455_2	697281.Mahau_1635	6.037e-44	168.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,42EVD@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
DYD2_k127_2345455_3	1266998.ATUJ01000003_gene1744	3.394e-13	77.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,2PXIH@265|Paracoccus	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
DYD2_k127_2345455_1	316056.RPC_0345	2.265e-102	342.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TS0T@28211|Alphaproteobacteria,3JRJ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC2	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
DYD2_k127_2345455_0	379066.GAU_1731	1.506e-137	458.0	COG0015@1|root,COG0015@2|Bacteria,1ZSVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
DYD2_k127_2345455_4	243231.GSU0080	0.0001056	49.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43T3R@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase S1 and S6, chymotrypsin Hap	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
DYD2_k127_2346421_3	555088.DealDRAFT_2974	2.309e-14	81.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,42JXF@68298|Syntrophomonadaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
DYD2_k127_2346421_0	379066.GAU_1532	5.711e-134	456.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,1ZT2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
DYD2_k127_2346421_2	379066.GAU_1531	3.218e-50	198.0	COG0324@1|root,COG0324@2|Bacteria,1ZTBB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
DYD2_k127_2346421_1	861299.J421_3155	7.339e-52	188.0	COG0323@1|root,COG0323@2|Bacteria,1ZT6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DYD2_k127_2346421_4	861299.J421_3155	7.628e-08	59.0	COG0323@1|root,COG0323@2|Bacteria,1ZT6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DYD2_k127_2372948_2	290397.Adeh_2637	1.662e-51	184.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,2Z30R@29|Myxococcales	28221|Deltaproteobacteria	C	fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DYD2_k127_2372948_0	1254432.SCE1572_38910	1.293e-112	375.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WK9D@28221|Deltaproteobacteria,2YXAV@29|Myxococcales	28221|Deltaproteobacteria	C	Fumarate reductase, iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2395	Fer2_3,Fer4_7,Fer4_8
DYD2_k127_2372948_1	309807.SRU_1723	4.522e-64	225.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
DYD2_k127_2399666_0	1379270.AUXF01000006_gene221	4.73e-117	382.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
DYD2_k127_2399666_1	330214.NIDE2649	3.929e-41	166.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
DYD2_k127_2407272_0	861299.J421_0313	2.831e-86	304.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
DYD2_k127_2407272_1	861299.J421_0542	7.748e-85	300.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
DYD2_k127_2407272_2	543728.Vapar_2692	5.815e-05	53.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,4A9JN@80864|Comamonadaceae	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
DYD2_k127_242543_1	324925.Ppha_2722	2.883e-116	386.0	COG0841@1|root,COG0841@2|Bacteria,1FDJ5@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DYD2_k127_242543_4	1303518.CCALI_01175	1.341e-14	85.0	COG0607@1|root,32YCZ@2|Bacteria	2|Bacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DYD2_k127_242543_3	330214.NIDE4245	3.494e-30	130.0	COG1595@1|root,COG1595@2|Bacteria,3J1A1@40117|Nitrospirae	40117|Nitrospirae	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_242543_0	309807.SRU_0326	1.079e-184	591.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,1FJ2U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
DYD2_k127_242543_5	331678.Cphamn1_2391	1.609e-12	71.0	COG2149@1|root,COG2149@2|Bacteria,1FFJW@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
DYD2_k127_242543_2	1123389.ATXJ01000001_gene491	2.897e-35	152.0	COG2193@1|root,COG2193@2|Bacteria,1WK3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Ferritin Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
DYD2_k127_242543_6	1288079.AUKN01000001_gene4109	5.515e-12	75.0	COG0789@1|root,COG0789@2|Bacteria,2I9B3@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
DYD2_k127_2427164_1	1454004.AW11_02474	2.746e-22	109.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,1KQ75@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	FAD binding domain	glcE	-	1.1.3.15	ko:K00104,ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
DYD2_k127_2427164_0	471852.Tcur_3271	1.52e-114	389.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4EFSX@85012|Streptosporangiales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
DYD2_k127_2427164_2	202952.BBLI01000003_gene293	7.616e-05	55.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria,3NQGN@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2427359_3	106370.Francci3_2499	1.493e-40	158.0	COG1999@1|root,COG1999@2|Bacteria,2GKF0@201174|Actinobacteria,4EVKF@85013|Frankiales	201174|Actinobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
DYD2_k127_2427359_2	379066.GAU_2938	6.182e-49	195.0	COG3336@1|root,COG3336@2|Bacteria	2|Bacteria	G	cytochrome c oxidase	ctaG	-	-	ko:K02351,ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
DYD2_k127_2427359_0	1192034.CAP_2960	1.48e-142	467.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42RF2@68525|delta/epsilon subdivisions,2WP05@28221|Deltaproteobacteria,2YWCM@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	allB	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DYD2_k127_2427359_1	1254432.SCE1572_35005	2.42e-127	423.0	COG3195@1|root,COG4266@1|root,COG3195@2|Bacteria,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,42YE0@68525|delta/epsilon subdivisions,2X30N@28221|Deltaproteobacteria,2YTWS@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
DYD2_k127_2427359_4	391625.PPSIR1_23599	6.646e-09	60.0	COG3195@1|root,COG3195@2|Bacteria,1RIGR@1224|Proteobacteria,438E6@68525|delta/epsilon subdivisions,2X3PB@28221|Deltaproteobacteria,2YWR6@29|Myxococcales	28221|Deltaproteobacteria	S	OHCU decarboxylase	-	-	4.1.1.97	ko:K16840	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
DYD2_k127_2448149_2	1191523.MROS_0448	5.552e-46	172.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_2448149_3	1318628.MARLIPOL_13024	0.0003436	51.0	COG5662@1|root,COG5662@2|Bacteria,1NG37@1224|Proteobacteria,1ST5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
DYD2_k127_2448149_0	1499967.BAYZ01000058_gene4762	4.628e-113	375.0	COG1363@1|root,COG1363@2|Bacteria,2NQGB@2323|unclassified Bacteria	2|Bacteria	G	M42 glutamyl aminopeptidase	frvX	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
DYD2_k127_2448149_1	861299.J421_4361	9.951e-71	246.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
DYD2_k127_2486525_0	1122604.JONR01000004_gene853	2.841e-78	290.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1T49A@1236|Gammaproteobacteria,1XDC3@135614|Xanthomonadales	135614|Xanthomonadales	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2486525_1	379066.GAU_3750	8.162e-25	122.0	COG0515@1|root,COG0515@2|Bacteria,1ZURQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DYD2_k127_2486525_2	861299.J421_4052	4.25e-21	106.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_4052|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2496780_6	1007103.AFHW01000170_gene2552	1.769e-12	74.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,4HR3T@91061|Bacilli,26ZWR@186822|Paenibacillaceae	91061|Bacilli	H	Thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DYD2_k127_2496780_4	309801.trd_0401	8.45e-25	120.0	COG0352@1|root,COG0352@2|Bacteria,2G9BW@200795|Chloroflexi,27YDG@189775|Thermomicrobia	189775|Thermomicrobia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
DYD2_k127_2496780_1	861299.J421_2566	6.823e-83	287.0	COG0223@1|root,COG0223@2|Bacteria,1ZTE5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
DYD2_k127_2496780_2	572477.Alvin_2073	3.016e-41	162.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1WXF4@135613|Chromatiales	135613|Chromatiales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
DYD2_k127_2496780_5	861299.J421_2568	5.21e-18	91.0	COG1862@1|root,COG1862@2|Bacteria,1ZU5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
DYD2_k127_2496780_0	293826.Amet_2342	1.068e-115	390.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,36FEZ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
DYD2_k127_2496780_3	760568.Desku_0671	1.312e-37	144.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,260V0@186807|Peptococcaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DYD2_k127_2519798_3	1385935.N836_12895	2.101e-17	96.0	2DBEV@1|root,2Z8UT@2|Bacteria,1G3XJ@1117|Cyanobacteria,1HA4M@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2519798_2	497964.CfE428DRAFT_1239	1.179e-31	144.0	2BZ6D@1|root,2ZC6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2519798_1	497964.CfE428DRAFT_1238	1.059e-179	595.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DYD2_k127_2519798_0	497964.CfE428DRAFT_1237	3.794e-203	646.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
DYD2_k127_2526270_0	861299.J421_0666	6.732e-142	458.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2526270_4	103733.JNYO01000002_gene750	1.423e-05	57.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
DYD2_k127_2526270_3	479435.Kfla_4891	1.164e-13	81.0	COG1977@1|root,COG1977@2|Bacteria,2GQM9@201174|Actinobacteria,4DW7X@85009|Propionibacteriales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DYD2_k127_2526270_5	861299.J421_0469	0.0007682	53.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_0469|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2526270_2	379066.GAU_0094	3.35e-27	129.0	COG0515@1|root,COG0515@2|Bacteria,1ZUHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DYD2_k127_2526270_1	313606.M23134_05229	5.167e-125	420.0	COG1858@1|root,COG1858@2|Bacteria,4NGX7@976|Bacteroidetes,47UB0@768503|Cytophagia	976|Bacteroidetes	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
DYD2_k127_2527397_0	941449.dsx2_1144	7.058e-166	533.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2MB2B@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
DYD2_k127_2527397_1	118166.JH976537_gene972	8.507e-140	452.0	COG1335@1|root,COG1335@2|Bacteria,1G10P@1117|Cyanobacteria,1H8R3@1150|Oscillatoriales	1117|Cyanobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2540037_1	861299.J421_2586	8.014e-33	146.0	COG1560@1|root,COG1560@2|Bacteria,1ZSTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
DYD2_k127_2540037_0	984262.SGRA_1125	1.346e-46	184.0	COG0463@1|root,COG0463@2|Bacteria,4NEZP@976|Bacteroidetes,1IPES@117747|Sphingobacteriia	976|Bacteroidetes	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
DYD2_k127_2540037_2	748449.Halha_2371	3.848e-12	73.0	COG2445@1|root,COG2445@2|Bacteria,1VF8K@1239|Firmicutes,24QTN@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
DYD2_k127_2540037_3	858215.Thexy_1760	5.438e-07	57.0	COG1669@1|root,COG1669@2|Bacteria,1V8YJ@1239|Firmicutes,25DTZ@186801|Clostridia,42GH8@68295|Thermoanaerobacterales	186801|Clostridia	L	Nucleotidyltransferase domain	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
DYD2_k127_2559303_4	1125863.JAFN01000001_gene1651	5.729e-17	84.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
DYD2_k127_2559303_0	404589.Anae109_3404	1.664e-97	339.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YUPC@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	crdA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DYD2_k127_2559303_5	1173028.ANKO01000246_gene4038	6.46e-17	94.0	COG0457@1|root,COG0457@2|Bacteria,1G1U5@1117|Cyanobacteria,1H859@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
DYD2_k127_2559303_1	595460.RRSWK_02465	3.63e-59	225.0	COG1181@1|root,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
DYD2_k127_2559303_7	215803.DB30_7942	7.119e-11	74.0	COG2214@1|root,COG2214@2|Bacteria,1PJXA@1224|Proteobacteria,433Y7@68525|delta/epsilon subdivisions,2X41U@28221|Deltaproteobacteria,2YXZY@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2559303_8	1223543.GP2_022_00850	0.0001267	54.0	COG4307@1|root,COG4307@2|Bacteria,2GKD6@201174|Actinobacteria,4GBWS@85026|Gordoniaceae	201174|Actinobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
DYD2_k127_2559303_3	390235.PputW619_2323	3.049e-28	119.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,1TADU@1236|Gammaproteobacteria,1YYAU@136845|Pseudomonas putida group	1236|Gammaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K08365	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind
DYD2_k127_2559303_2	523791.Kkor_2400	5.996e-50	184.0	COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,1SAKR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2559303_6	394221.Mmar10_0334	1.647e-13	76.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_16,TPR_8,Trans_reg_C
DYD2_k127_2559830_6	1110697.NCAST_20_05470	0.0008308	50.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4FVFA@85025|Nocardiaceae	201174|Actinobacteria	E	peptidyl-arginine modification	arcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
DYD2_k127_2559830_1	861299.J421_3451	3.13e-53	196.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
DYD2_k127_2559830_3	518766.Rmar_2603	6.67e-45	181.0	COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1FJ8S@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
DYD2_k127_2559830_0	861299.J421_3453	1.256e-89	315.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1ZSPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
DYD2_k127_2559830_5	644282.Deba_1225	5.44e-26	117.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria,1PGJ3@1224|Proteobacteria,4315J@68525|delta/epsilon subdivisions,2WWDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
DYD2_k127_2559830_4	861299.J421_3455	4.077e-40	152.0	COG1366@1|root,COG1366@2|Bacteria,1ZTXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
DYD2_k127_2559830_2	379066.GAU_1886	2.299e-46	171.0	COG0280@1|root,COG0280@2|Bacteria,1ZT01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
DYD2_k127_2564025_1	394221.Mmar10_1811	0.0003404	54.0	COG0457@1|root,COG0457@2|Bacteria,1REXI@1224|Proteobacteria,2UB1S@28211|Alphaproteobacteria,43XG9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5,TPR_16,TPR_19,TPR_8
DYD2_k127_2564025_0	379066.GAU_2731	4.443e-05	53.0	COG0468@1|root,COG0468@2|Bacteria,1ZUMI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Rad51	-	-	-	-	-	-	-	-	-	-	-	-	RecA
DYD2_k127_257184_8	886293.Sinac_0544	2.538e-35	136.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	yhhY	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	2.3.1.128,2.3.1.178	ko:K03790,ko:K03825,ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_4
DYD2_k127_257184_3	1217718.ALOU01000031_gene1598	1.193e-69	244.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria,1K5JG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
DYD2_k127_257184_10	1218084.BBJK01000025_gene2545	1.068e-32	132.0	COG3556@1|root,COG3556@2|Bacteria,1N3XH@1224|Proteobacteria,2VRQ4@28216|Betaproteobacteria,1K72R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
DYD2_k127_257184_4	986075.CathTA2_1906	2.715e-58	207.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli	91061|Bacilli	M	Sortase and related acyltransferases	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
DYD2_k127_257184_9	543728.Vapar_1346	3.861e-33	132.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2VVJM@28216|Betaproteobacteria,4AEUN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
DYD2_k127_257184_11	1502851.FG93_03414	4.225e-12	72.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	bacB	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CDO_I,Cupin_2
DYD2_k127_257184_5	1395587.P364_0113550	3.819e-54	196.0	COG1670@1|root,COG1670@2|Bacteria,1V54D@1239|Firmicutes,4HIQW@91061|Bacilli,26Y91@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
DYD2_k127_257184_7	373994.Riv7116_0738	1.079e-41	165.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
DYD2_k127_257184_2	765420.OSCT_0361	1.735e-71	254.0	COG1272@1|root,COG1272@2|Bacteria,2G7B7@200795|Chloroflexi,3774B@32061|Chloroflexia	32061|Chloroflexia	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
DYD2_k127_257184_6	1144275.COCOR_07590	2.978e-45	179.0	COG3554@1|root,COG3554@2|Bacteria,1PV1V@1224|Proteobacteria,42XVB@68525|delta/epsilon subdivisions,2WXJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
DYD2_k127_257184_1	1280950.HJO_17349	1.658e-82	290.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2U0A3@28211|Alphaproteobacteria,43YRN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
DYD2_k127_257184_0	1499967.BAYZ01000095_gene4087	2.748e-85	289.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
DYD2_k127_258936_9	1122180.Lokhon_00089	2.334e-35	155.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
DYD2_k127_258936_7	1499967.BAYZ01000090_gene4954	1.313e-36	161.0	COG0500@1|root,COG2226@2|Bacteria,2NQZU@2323|unclassified Bacteria	2|Bacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
DYD2_k127_258936_0	1089551.KE386572_gene2268	3.937e-205	679.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,4BQ5I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
DYD2_k127_258936_2	1089551.KE386572_gene2269	1.029e-104	365.0	COG0438@1|root,COG0438@2|Bacteria,1PHA6@1224|Proteobacteria,2V852@28211|Alphaproteobacteria,4BSY5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
DYD2_k127_258936_8	1122180.Lokhon_00120	8.869e-36	149.0	29CTD@1|root,2ZZRI@2|Bacteria,1N28P@1224|Proteobacteria,2UDZI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_258936_1	1195246.AGRI_00715	2.363e-123	421.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,469ZI@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
DYD2_k127_258936_4	766499.C357_22955	7.398e-74	263.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,2TTR9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD2_k127_258936_5	472759.Nhal_3328	4.513e-45	183.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1WXFS@135613|Chromatiales	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
DYD2_k127_258936_3	1123371.ATXH01000019_gene615	2.14e-100	343.0	COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
DYD2_k127_258936_6	379066.GAU_2427	3.508e-42	169.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DYD2_k127_2594365_3	861299.J421_3756	4.609e-25	121.0	2EFCU@1|root,3395Q@2|Bacteria,1ZTVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2594365_2	861299.J421_3755	5.472e-70	268.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2594365_1	861299.J421_3754	6.949e-85	291.0	COG0524@1|root,COG0524@2|Bacteria,1ZTFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2594365_0	861299.J421_3753	6.689e-120	398.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
DYD2_k127_2594365_4	1463909.KL585972_gene3392	4.121e-17	86.0	COG0859@1|root,COG0859@2|Bacteria,2GSTW@201174|Actinobacteria	201174|Actinobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Hydrolase_like
DYD2_k127_2646289_3	439235.Dalk_3618	5.131e-48	184.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria,2MIHF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DYD2_k127_2646289_4	671143.DAMO_1161	5.594e-45	185.0	COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
DYD2_k127_2646289_2	671143.DAMO_3001	8.55e-50	191.0	COG1989@1|root,COG1989@2|Bacteria,2NPDS@2323|unclassified Bacteria	2|Bacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02236,ko:K02278,ko:K02506,ko:K02654,ko:K10966	-	M00331,M00429	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
DYD2_k127_2646289_5	1128421.JAGA01000002_gene76	8.657e-33	146.0	COG0566@1|root,COG0566@2|Bacteria,2NPZQ@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
DYD2_k127_2646289_6	1158756.AQXQ01000007_gene380	1.058e-27	125.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales	135613|Chromatiales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DYD2_k127_2646289_0	357808.RoseRS_1921	1.408e-68	258.0	COG0351@1|root,COG0351@2|Bacteria,2G5R7@200795|Chloroflexi,375EX@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Phosphomethylpyrimidine kinase type-1	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
DYD2_k127_2646289_1	861299.J421_3835	7.068e-68	235.0	COG0005@1|root,COG0005@2|Bacteria,1ZTGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DYD2_k127_2653893_4	1287116.X734_18870	3.566e-06	55.0	COG0491@1|root,COG0491@2|Bacteria,1Q861@1224|Proteobacteria,2U29C@28211|Alphaproteobacteria,43JH3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DYD2_k127_2653893_0	644966.Tmar_1012	2.973e-181	576.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WCC9@538999|Clostridiales incertae sedis	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
DYD2_k127_2653893_3	525904.Tter_0551	1.622e-91	313.0	COG3294@1|root,COG3294@2|Bacteria,2NR9E@2323|unclassified Bacteria	2|Bacteria	S	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
DYD2_k127_2653893_2	1123368.AUIS01000024_gene950	2.618e-153	511.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,2NCJF@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DYD2_k127_2653893_1	1123368.AUIS01000024_gene949	2.363e-162	519.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2NBU9@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DYD2_k127_2656959_0	405948.SACE_3077	6.692e-154	501.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria,4DYVA@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
DYD2_k127_2677536_3	1123261.AXDW01000001_gene1332	2.06e-71	271.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1X97T@135614|Xanthomonadales	135614|Xanthomonadales	M	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA,TSP_3
DYD2_k127_2677536_7	649638.Trad_2611	2.775e-13	83.0	COG0580@1|root,COG0580@2|Bacteria,1WMH8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Glycerol uptake facilitator GlpF, MIP aquaporin family of transporters	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
DYD2_k127_2677536_4	1235803.C825_02301	6.666e-35	153.0	COG1215@1|root,COG1215@2|Bacteria,4NQ1I@976|Bacteroidetes,2FTMT@200643|Bacteroidia,230HG@171551|Porphyromonadaceae	976|Bacteroidetes	M	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C
DYD2_k127_2677536_1	448385.sce2438	5.055e-100	341.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42UHT@68525|delta/epsilon subdivisions,2WR0M@28221|Deltaproteobacteria,2YUP9@29|Myxococcales	28221|Deltaproteobacteria	C	oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
DYD2_k127_2677536_0	1382356.JQMP01000001_gene813	1.204e-160	520.0	COG1271@1|root,COG1271@2|Bacteria,2G63Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome bd ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
DYD2_k127_2677536_5	1237149.C900_03285	5.879e-24	120.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_2677536_2	290397.Adeh_1197	3.539e-86	312.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
DYD2_k127_2677536_6	290397.Adeh_1198	1.931e-17	83.0	COG0636@1|root,COG0636@2|Bacteria,1N5D3@1224|Proteobacteria,438SF@68525|delta/epsilon subdivisions,2WY87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM H transporting two-sector ATPase C subunit	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
DYD2_k127_2706881_1	187272.Mlg_1158	3.061e-35	136.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria,1X0JQ@135613|Chromatiales	135613|Chromatiales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2706881_0	743721.Psesu_2005	3.391e-49	190.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1X3CE@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
DYD2_k127_2706881_2	861299.J421_1305	4.041e-16	87.0	28YSJ@1|root,343H2@2|Bacteria,1ZU2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2717031_4	1068978.AMETH_0943	5.877e-16	80.0	COG1611@1|root,COG1611@2|Bacteria,2GMM1@201174|Actinobacteria,4E2JN@85010|Pseudonocardiales	201174|Actinobacteria	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Lysine_decarbox,NUDIX
DYD2_k127_2717031_0	1121930.AQXG01000005_gene597	1.278e-85	301.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,1IUKS@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DYD2_k127_2717031_1	1541065.JRFE01000001_gene2598	3.591e-82	280.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria,3VIB9@52604|Pleurocapsales	1117|Cyanobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
DYD2_k127_2717031_2	1379270.AUXF01000001_gene2030	1.688e-64	234.0	COG0300@1|root,COG0300@2|Bacteria,1ZUD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DYD2_k127_2717031_3	861299.J421_2906	2.241e-48	181.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
DYD2_k127_2727640_0	1379270.AUXF01000006_gene38	2.758e-190	609.0	COG1674@1|root,COG1674@2|Bacteria,1ZSPI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
DYD2_k127_2728867_3	710111.FraQA3DRAFT_2993	1.444e-21	102.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4ESVX@85013|Frankiales	201174|Actinobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	rffE	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
DYD2_k127_2728867_0	1379270.AUXF01000004_gene3319	2.62e-152	497.0	COG2204@1|root,COG2204@2|Bacteria,1ZSZ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DYD2_k127_2728867_2	1123519.PSJM300_15075	6.275e-22	112.0	COG3614@1|root,COG5002@1|root,COG3614@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RWNG@1236|Gammaproteobacteria,1Z02U@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg
DYD2_k127_2728867_1	861299.J421_3591	6.402e-58	211.0	COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
DYD2_k127_2740523_0	1192034.CAP_5366	1.851e-127	434.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YTZB@29|Myxococcales	28221|Deltaproteobacteria	E	synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
DYD2_k127_2740523_2	861299.J421_3942	1.742e-105	352.0	COG1208@1|root,COG1208@2|Bacteria,1ZSYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DYD2_k127_2740523_1	518766.Rmar_0956	6.938e-109	371.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1FIV5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
DYD2_k127_2740523_3	522772.Dacet_1568	5.591e-08	67.0	COG4399@1|root,COG4399@2|Bacteria,2GER8@200930|Deferribacteres	200930|Deferribacteres	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
DYD2_k127_2740523_4	272557.APE_1648.1	5.708e-06	55.0	COG2110@1|root,arCOG04225@2157|Archaea,2XQEQ@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
DYD2_k127_274273_2	1267533.KB906733_gene3413	2.336e-22	109.0	COG0451@1|root,COG0451@2|Bacteria,3Y7GG@57723|Acidobacteria	57723|Acidobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
DYD2_k127_274273_3	251221.35214614	3.378e-18	95.0	COG1186@1|root,COG1186@2|Bacteria,1GDQK@1117|Cyanobacteria	1117|Cyanobacteria	J	RF-1 domain	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
DYD2_k127_274273_0	1232410.KI421413_gene790	1.566e-53	203.0	29DWE@1|root,300UA@2|Bacteria,1PTJM@1224|Proteobacteria,432M4@68525|delta/epsilon subdivisions,2WYHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
DYD2_k127_274273_1	861299.J421_1883	4.415e-33	143.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	2|Bacteria	K	Sigma-70, region 4	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_2755152_0	589865.DaAHT2_0540	1.703e-146	481.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2WKBM@28221|Deltaproteobacteria,2MHN3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
DYD2_k127_2755152_1	930169.B5T_04131	4.968e-19	100.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,1S2HV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
DYD2_k127_2767056_1	518766.Rmar_1805	2.686e-37	160.0	COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1FIMJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
DYD2_k127_2767056_0	1379270.AUXF01000006_gene36	5.972e-162	523.0	COG0439@1|root,COG0439@2|Bacteria,1ZT0Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DYD2_k127_2767056_3	768670.Calni_0235	0.0001107	49.0	COG0439@1|root,COG0439@2|Bacteria,2GFAC@200930|Deferribacteres	200930|Deferribacteres	I	Pfam:CPSase_L_chain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
DYD2_k127_2767056_2	1123376.AUIU01000013_gene1763	5.132e-30	120.0	COG0511@1|root,COG0511@2|Bacteria,3J0PI@40117|Nitrospirae	40117|Nitrospirae	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
DYD2_k127_2805829_1	861299.J421_2570	5.909e-51	191.0	COG0809@1|root,COG0809@2|Bacteria,1ZSV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
DYD2_k127_2805829_0	861299.J421_2575	6.525e-142	459.0	COG2255@1|root,COG2255@2|Bacteria,1ZT9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
DYD2_k127_2805829_3	379066.GAU_0633	2.398e-33	143.0	COG0632@1|root,COG0632@2|Bacteria,1ZTR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
DYD2_k127_2805829_2	861299.J421_2580	1.829e-39	153.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
DYD2_k127_2810571_4	1128427.KB904821_gene3303	1.133e-21	104.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DYD2_k127_2810571_6	1089550.ATTH01000001_gene465	5.483e-05	53.0	COG5615@1|root,COG5615@2|Bacteria,4P6NC@976|Bacteroidetes,1FK4A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	CopD
DYD2_k127_2810571_5	861299.J421_6042	1.973e-10	70.0	2EGPU@1|root,31UHV@2|Bacteria,1ZV7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2810571_3	861299.J421_6043	6.941e-26	119.0	2AUAW@1|root,31JYI@2|Bacteria,1ZV7R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2810571_0	861299.J421_6044	3.945e-299	930.0	COG2192@1|root,COG2192@2|Bacteria,1ZUTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
DYD2_k127_2810571_2	1304275.C41B8_09426	6.263e-67	246.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,1S25V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DYD2_k127_2810571_1	479434.Sthe_2273	1.354e-72	252.0	COG0277@1|root,COG0277@2|Bacteria,2G8B5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
DYD2_k127_2848925_2	247490.KSU1_C0826	1.241e-59	220.0	COG1691@1|root,COG1691@2|Bacteria,2IYZT@203682|Planctomycetes	203682|Planctomycetes	S	COG1691 NCAIR mutase (PurE)-related	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
DYD2_k127_2848925_1	861299.J421_3386	8.654e-66	237.0	COG1762@1|root,COG1762@2|Bacteria,1ZTIY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
DYD2_k127_2848925_4	1158345.JNLL01000001_gene902	4.712e-07	60.0	COG1579@1|root,COG1579@2|Bacteria,2G4TK@200783|Aquificae	200783|Aquificae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
DYD2_k127_2848925_0	1307759.JOMJ01000004_gene2763	2.134e-116	398.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2M8QA@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
DYD2_k127_2848925_3	861299.J421_3135	9.443e-30	126.0	COG1381@1|root,COG1381@2|Bacteria,1ZTHP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
DYD2_k127_2874277_2	1089550.ATTH01000001_gene363	2.323e-21	110.0	COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1FJXK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
DYD2_k127_2874277_1	861299.J421_6041	9.857e-49	192.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Lipase_GDSL_3,SASA
DYD2_k127_2874277_3	863365.XHC_1752	5.114e-05	50.0	2ANYG@1|root,31DZF@2|Bacteria,1QB9H@1224|Proteobacteria,1T6TX@1236|Gammaproteobacteria,1X857@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2874277_0	518766.Rmar_1401	3.784e-168	531.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,1FJ4C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DYD2_k127_2883358_0	379066.GAU_1447	5.62e-178	585.0	COG0017@1|root,COG0017@2|Bacteria,1ZSTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DYD2_k127_2883358_1	429009.Adeg_0126	1.087e-100	338.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,42ES5@68295|Thermoanaerobacterales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
DYD2_k127_2895937_1	1379270.AUXF01000004_gene2972	2.933e-58	207.0	COG4948@1|root,COG4948@2|Bacteria,1ZSKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
DYD2_k127_2895937_0	861299.J421_2825	1.015e-191	612.0	COG1198@1|root,COG1198@2|Bacteria,1ZTE9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
DYD2_k127_2900637_3	379066.GAU_1876	7.633e-39	147.0	COG0292@1|root,COG0292@2|Bacteria,1ZTUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
DYD2_k127_2900637_4	945713.IALB_1437	2.294e-14	75.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
DYD2_k127_2900637_1	644966.Tmar_0826	1.71e-50	198.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3WCI3@538999|Clostridiales incertae sedis	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
DYD2_k127_2900637_5	1484460.JSWG01000009_gene211	1.006e-07	63.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1I47M@117743|Flavobacteriia	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DYD2_k127_2900637_6	1429851.X548_08950	2.51e-06	59.0	2C312@1|root,2Z7N1@2|Bacteria,1R9N9@1224|Proteobacteria,1S1HP@1236|Gammaproteobacteria,1X7YE@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2900637_0	861299.J421_3884	1.148e-52	194.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_2900637_2	926692.AZYG01000036_gene2552	6.399e-46	178.0	COG0668@1|root,COG0668@2|Bacteria,1V6AH@1239|Firmicutes,24KED@186801|Clostridia,3WBS8@53433|Halanaerobiales	186801|Clostridia	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
DYD2_k127_291630_0	1047013.AQSP01000102_gene979	5.916e-132	458.0	COG0841@1|root,COG0841@2|Bacteria,2NQF8@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DYD2_k127_291630_2	237368.SCABRO_01440	2.787e-10	74.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DYD2_k127_291630_1	477974.Daud_2099	3.286e-74	269.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,260X3@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DYD2_k127_2955857_1	1254432.SCE1572_01825	1.15e-208	671.0	COG3857@1|root,COG3857@2|Bacteria,1QXU1@1224|Proteobacteria,43C6K@68525|delta/epsilon subdivisions,2X7GU@28221|Deltaproteobacteria,2Z1DQ@29|Myxococcales	28221|Deltaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
DYD2_k127_2955857_3	322710.Avin_27680	3.131e-18	100.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,1SAC3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid maintenance system killer protein	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
DYD2_k127_2955857_2	1047013.AQSP01000114_gene700	5.877e-42	155.0	COG3093@1|root,COG3093@2|Bacteria,2NR60@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
DYD2_k127_2955857_0	1192034.CAP_3147	3.509e-219	703.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,2YUG5@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
DYD2_k127_2999845_0	644966.Tmar_0901	2.078e-207	666.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
DYD2_k127_2999845_3	1121877.JQKF01000018_gene2547	4.542e-27	130.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4CN1R@84992|Acidimicrobiia	84992|Acidimicrobiia	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_2999845_2	105422.BBPM01000067_gene388	2.24e-48	195.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,2NG9W@228398|Streptacidiphilus	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DYD2_k127_2999845_1	1123368.AUIS01000013_gene855	1.101e-66	247.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,2NBQK@225057|Acidithiobacillales	225057|Acidithiobacillales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DYD2_k127_3002443_1	1173020.Cha6605_5469	4.26e-42	172.0	2A70U@1|root,30VW1@2|Bacteria,1G5C4@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
DYD2_k127_3002443_0	459349.CLOAM1637	4.491e-43	172.0	COG2859@1|root,COG2859@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
DYD2_k127_3002443_2	313606.M23134_06177	2.45e-07	63.0	COG4320@1|root,COG4320@2|Bacteria,4P18K@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
DYD2_k127_3010193_4	379066.GAU_0276	3.632e-67	248.0	COG0475@1|root,COG0475@2|Bacteria,1ZTBI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DYD2_k127_3010193_3	379066.GAU_0276	5.812e-70	255.0	COG0475@1|root,COG0475@2|Bacteria,1ZTBI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DYD2_k127_3010193_2	379066.GAU_0276	3.599e-73	264.0	COG0475@1|root,COG0475@2|Bacteria,1ZTBI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DYD2_k127_3010193_1	58123.JOFJ01000027_gene2790	6.093e-128	441.0	COG0531@1|root,COG0531@2|Bacteria,2H98W@201174|Actinobacteria,4EN0D@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
DYD2_k127_3010193_0	861299.J421_4156	5.089e-149	482.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
DYD2_k127_302297_0	861299.J421_3234	4.43e-88	302.0	COG1625@1|root,COG1625@2|Bacteria,1ZSQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
DYD2_k127_302297_1	518766.Rmar_0960	0.0003489	51.0	2DHC9@1|root,2ZZ7D@2|Bacteria,4PEUK@976|Bacteroidetes,1FJMV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
DYD2_k127_3024978_2	1122604.JONR01000031_gene1240	7.318e-06	57.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RQ36@1236|Gammaproteobacteria,1XCGH@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
DYD2_k127_3024978_0	207559.Dde_1846	1.073e-156	507.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2M86Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
DYD2_k127_3024978_1	266117.Rxyl_2397	1.639e-68	244.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4CQEZ@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
DYD2_k127_3025721_3	861299.J421_3400	2.687e-112	377.0	COG0612@1|root,COG0612@2|Bacteria,1ZSPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DYD2_k127_3025721_1	861299.J421_3399	9.151e-160	518.0	COG0686@1|root,COG0686@2|Bacteria,1ZSSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
DYD2_k127_3025721_0	861299.J421_3398	4.995e-163	523.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
DYD2_k127_3025721_7	379066.GAU_1760	8.546e-35	146.0	COG1792@1|root,COG1792@2|Bacteria,1ZSYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
DYD2_k127_3025721_2	379066.GAU_1758	1.775e-133	458.0	COG0768@1|root,COG0768@2|Bacteria,1ZSX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
DYD2_k127_3025721_4	379066.GAU_1757	2.287e-107	362.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
DYD2_k127_3025721_5	880073.Calab_0770	4.457e-98	329.0	COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
DYD2_k127_3025721_6	861299.J421_3392	1.105e-71	276.0	COG0285@1|root,COG0285@2|Bacteria,1ZSRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
DYD2_k127_3025721_8	1121346.KB899820_gene2763	1.379e-25	119.0	28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,26WPV@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0403 family	yphP	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
DYD2_k127_3025721_9	379066.GAU_3064	7.073e-17	80.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
DYD2_k127_304532_0	404589.Anae109_1625	1.262e-117	398.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_304532_1	1298863.AUEP01000013_gene4059	3.824e-07	52.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4DRK2@85009|Propionibacteriales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
DYD2_k127_3066606_0	420324.KI912084_gene7403	2.028e-06	60.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,1JSYN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HEAT_2,Rhodanese,TPR_16,TPR_19,TPR_8,TolB_N
DYD2_k127_3075176_2	323261.Noc_0394	2.187e-88	302.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1WVZX@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
DYD2_k127_3075176_1	472759.Nhal_1354	6.907e-101	342.0	COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,1WYC3@135613|Chromatiales	135613|Chromatiales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DYD2_k127_3075176_3	518766.Rmar_2038	2.436e-34	150.0	2A9WE@1|root,30Z4D@2|Bacteria,4PESJ@976|Bacteroidetes,1FJJ1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3075176_0	1297742.A176_00323	5.9e-115	381.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DYD2_k127_3079828_1	861299.J421_3119	1.058e-115	383.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DYD2_k127_3079828_4	861299.J421_3118	2.365e-21	106.0	COG0781@1|root,COG0781@2|Bacteria,1ZTRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
DYD2_k127_3079828_3	1304874.JAFY01000007_gene2421	6.968e-39	156.0	COG0054@1|root,COG0054@2|Bacteria,3TAV8@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
DYD2_k127_3079828_0	861299.J421_3116	4.256e-168	538.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1ZT7J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
DYD2_k127_3079828_2	446465.Bfae_00070	5.361e-44	167.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4FCSV@85020|Dermabacteraceae	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
DYD2_k127_3092748_0	1254432.SCE1572_50085	2.766e-289	912.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2YUA8@29|Myxococcales	28221|Deltaproteobacteria	J	glutaminyl-tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
DYD2_k127_3092748_2	861299.J421_0886	2.705e-48	190.0	COG1595@1|root,COG1595@2|Bacteria,1ZUWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DYD2_k127_3092748_1	1379270.AUXF01000001_gene2437	1.074e-81	284.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
DYD2_k127_3093693_4	869210.Marky_1598	0.0004912	51.0	COG1394@1|root,COG1394@2|Bacteria,1WJXJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
DYD2_k127_3093693_2	404589.Anae109_2563	1.38e-56	201.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
DYD2_k127_3093693_1	290397.Adeh_1203	2.836e-89	328.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
DYD2_k127_3093693_0	290397.Adeh_1202	9.074e-195	628.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
DYD2_k127_3093693_3	290397.Adeh_1201	8.603e-08	61.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
DYD2_k127_3094657_2	1278073.MYSTI_01185	2.594e-07	63.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DYD2_k127_3094657_0	861299.J421_1260	6.312e-130	431.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DYD2_k127_3094657_1	861299.J421_1260	1.034e-17	86.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DYD2_k127_3110206_0	861299.J421_4453	1.371e-194	624.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1ZTC2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
DYD2_k127_3110206_2	379066.GAU_0703	1.102e-107	358.0	COG0500@1|root,COG2226@2|Bacteria,1ZSM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
DYD2_k127_3110206_4	671143.DAMO_1125	2.075e-22	102.0	COG0640@1|root,COG0640@2|Bacteria,2NQ4D@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
DYD2_k127_3110206_5	1541065.JRFE01000058_gene5541	2.591e-06	56.0	2DBIE@1|root,32ZYG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3110206_1	1123242.JH636435_gene2759	4.398e-124	419.0	COG2355@1|root,COG2355@2|Bacteria,2IXYG@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase M19 renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
DYD2_k127_3110206_3	861299.J421_4334	9.265e-38	162.0	COG1607@1|root,COG1607@2|Bacteria,1ZTQ1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
DYD2_k127_3110206_6	861299.J421_2752	5.401e-05	46.0	COG1760@1|root,COG1760@2|Bacteria,1ZT3U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
DYD2_k127_3147185_0	379066.GAU_1554	1.462e-164	531.0	COG0195@1|root,COG0195@2|Bacteria,1ZSNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
DYD2_k127_3147185_1	429009.Adeg_1666	1.217e-07	55.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,42GU2@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
DYD2_k127_3193670_4	861299.J421_1152	7.562e-15	85.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DYD2_k127_3193670_5	1382306.JNIM01000001_gene3762	4.624e-12	77.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DYD2_k127_3193670_6	326427.Cagg_2563	1.476e-06	61.0	COG5479@1|root,COG5479@2|Bacteria,2G970@200795|Chloroflexi,3763R@32061|Chloroflexia	32061|Chloroflexia	M	peptidoglycan receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DYD2_k127_3193670_0	330214.NIDE0738	7.612e-81	308.0	COG0463@1|root,COG0463@2|Bacteria,3J13V@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
DYD2_k127_3193670_1	886293.Sinac_3585	2.099e-58	233.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
DYD2_k127_3193670_3	886293.Sinac_3585	1.252e-37	165.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
DYD2_k127_3193670_2	1242864.D187_006518	7.276e-52	209.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2X8PP@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DYD2_k127_3194298_5	395493.BegalDRAFT_3488	7.526e-48	189.0	COG3203@1|root,COG3203@2|Bacteria,1P7S0@1224|Proteobacteria,1S09X@1236|Gammaproteobacteria,46286@72273|Thiotrichales	72273|Thiotrichales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
DYD2_k127_3194298_2	1380390.JIAT01000010_gene4331	3.671e-76	267.0	COG1907@1|root,COG1907@2|Bacteria,2IGTW@201174|Actinobacteria	201174|Actinobacteria	S	transferase activity, transferring glycosyl groups	-	-	2.4.2.54	ko:K06984	ko00790,map00790	-	R10337,R11102	-	ko00000,ko00001,ko01000	-	-	-	-
DYD2_k127_3194298_4	1380390.JIAT01000010_gene4330	1.403e-54	199.0	COG2457@1|root,COG2457@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF447)	-	-	-	ko:K09154	-	-	-	-	ko00000	-	-	-	DUF447
DYD2_k127_3194298_3	429009.Adeg_1161	2.278e-73	254.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,42G1H@68295|Thermoanaerobacterales	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DYD2_k127_3194298_1	264732.Moth_2108	6.038e-130	432.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,42FM5@68295|Thermoanaerobacterales	186801|Clostridia	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
DYD2_k127_3194298_0	1380390.JIAT01000010_gene4319	1.707e-155	503.0	COG0294@1|root,COG0294@2|Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DYD2_k127_3207720_0	195250.CM001776_gene3959	2.499e-13	79.0	COG0810@1|root,COG0810@2|Bacteria,1GNYG@1117|Cyanobacteria,1H1WK@1129|Synechococcus	1117|Cyanobacteria	M	TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DYD2_k127_3207720_2	391615.ABSJ01000002_gene467	0.0002972	50.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3207720_1	1121904.ARBP01000003_gene6312	4.287e-07	56.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_8
DYD2_k127_3285605_0	518766.Rmar_0538	2.835e-131	428.0	COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
DYD2_k127_3285605_1	1244869.H261_05779	5.377e-22	110.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2U5HG@28211|Alphaproteobacteria,2JSW6@204441|Rhodospirillales	204441|Rhodospirillales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
DYD2_k127_3300100_3	1237149.C900_02048	2.793e-19	90.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3300100_2	1229909.NSED_06605	9.897e-30	136.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	ko:K21990	-	-	-	-	ko00000	1.A.16.4	-	-	Form_Nir_trans,Thioredoxin_4
DYD2_k127_3300100_0	525904.Tter_1676	2.975e-56	200.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
DYD2_k127_3300100_1	370438.PTH_1424	8.414e-38	151.0	COG2227@1|root,COG2227@2|Bacteria,1UGIP@1239|Firmicutes,24KA4@186801|Clostridia,2626I@186807|Peptococcaceae	186801|Clostridia	H	PFAM O-methyltransferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
DYD2_k127_3300100_4	263358.VAB18032_18030	0.000706	49.0	COG0500@1|root,COG2226@2|Bacteria,2IEAN@201174|Actinobacteria,4DM18@85008|Micromonosporales	201174|Actinobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25
DYD2_k127_3351767_7	290397.Adeh_3776	0.0006594	52.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2YVR5@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
DYD2_k127_3351767_6	292459.STH1211	9.074e-38	161.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
DYD2_k127_3351767_2	861299.J421_3077	5.247e-90	319.0	COG0773@1|root,COG0773@2|Bacteria,1ZSQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DYD2_k127_3351767_4	861299.J421_3076	1.485e-72	258.0	COG0707@1|root,COG0707@2|Bacteria,1ZSW5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
DYD2_k127_3351767_5	1329516.JPST01000035_gene3124	2.33e-70	267.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,27BGU@186824|Thermoactinomycetaceae	91061|Bacilli	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
DYD2_k127_3351767_1	861299.J421_3074	9.68e-107	384.0	COG0771@1|root,COG0771@2|Bacteria,1ZT38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
DYD2_k127_3351767_0	1379270.AUXF01000005_gene687	6.695e-117	398.0	COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
DYD2_k127_3351767_3	861299.J421_3072	4.662e-83	293.0	COG0770@1|root,COG0770@2|Bacteria,1ZT1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DYD2_k127_3381341_0	1179778.PMM47T1_08761	2.51e-76	260.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,1RZPD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	EHN
DYD2_k127_3381341_1	1379270.AUXF01000002_gene1364	6.004e-73	271.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1364|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_339025_3	675635.Psed_4744	7.275e-20	98.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4E2W5@85010|Pseudonocardiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
DYD2_k127_339025_0	861299.J421_3824	7.238e-78	276.0	COG0336@1|root,COG0336@2|Bacteria,1ZT8K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
DYD2_k127_339025_2	1499680.CCFE01000024_gene2761	6.324e-38	158.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,1ZGDK@1386|Bacillus	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
DYD2_k127_339025_1	321332.CYB_1824	1.827e-48	180.0	COG0164@1|root,COG0164@2|Bacteria,1G507@1117|Cyanobacteria,1H0B0@1129|Synechococcus	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
DYD2_k127_3439217_3	105559.Nwat_2301	2.785e-31	129.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales	135613|Chromatiales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
DYD2_k127_3439217_0	861299.J421_3410	2.502e-97	323.0	COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
DYD2_k127_3439217_1	266117.Rxyl_1401	6.899e-53	192.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CQ2J@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
DYD2_k127_3439217_2	498761.HM1_0679	1.035e-32	137.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
DYD2_k127_3439627_0	1382306.JNIM01000001_gene4091	6.252e-99	336.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
DYD2_k127_3439627_3	861299.J421_3320	3.22e-12	69.0	28VAR@1|root,2ZHDJ@2|Bacteria,1ZU25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
DYD2_k127_3439627_2	379066.GAU_1689	2.375e-49	187.0	COG0194@1|root,COG0194@2|Bacteria,1ZTV7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
DYD2_k127_3439627_1	1379270.AUXF01000006_gene201	8.487e-59	215.0	COG1561@1|root,COG1561@2|Bacteria,1ZT99@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
DYD2_k127_3439627_4	243231.GSU0332	5.895e-11	63.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
DYD2_k127_3451308_2	861299.J421_2617	3.368e-48	189.0	COG1092@1|root,COG1092@2|Bacteria,1ZT8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DYD2_k127_3451308_0	760192.Halhy_5770	4.455e-97	329.0	COG1816@1|root,COG1816@2|Bacteria,4NJ8S@976|Bacteroidetes,1IWMN@117747|Sphingobacteriia	976|Bacteroidetes	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
DYD2_k127_3451308_3	448385.sce1953	3.623e-23	106.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
DYD2_k127_3451308_1	861299.J421_4375	5.068e-52	190.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_3451308_5	1297742.A176_03720	0.0001613	52.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
DYD2_k127_3468358_2	861299.J421_2628	6.949e-78	267.0	COG0224@1|root,COG0224@2|Bacteria,1ZSZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
DYD2_k127_3468358_0	861299.J421_2627	4.475e-231	727.0	COG0056@1|root,COG0056@2|Bacteria,1ZSNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
DYD2_k127_3468358_4	861299.J421_3944	8.034e-29	130.0	COG0712@1|root,COG0712@2|Bacteria,1ZTP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
DYD2_k127_3468358_6	1519464.HY22_12910	2.262e-18	100.0	COG0711@1|root,COG0711@2|Bacteria,1FDW3@1090|Chlorobi	1090|Chlorobi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
DYD2_k127_3468358_7	861299.J421_3946	1.687e-17	85.0	COG0636@1|root,COG0636@2|Bacteria,1ZU1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
DYD2_k127_3468358_3	861299.J421_3947	5.522e-68	245.0	COG0356@1|root,COG0356@2|Bacteria,1ZSQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
DYD2_k127_3468358_1	861299.J421_3951	2.23e-132	432.0	COG0714@1|root,COG0714@2|Bacteria,1ZT5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
DYD2_k127_3468358_5	694440.JOMF01000009_gene672	5.793e-28	117.0	COG1253@1|root,arCOG00626@2157|Archaea,2XT1Z@28890|Euryarchaeota,2N962@224756|Methanomicrobia	224756|Methanomicrobia	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DYD2_k127_3496334_0	330214.NIDE3501	2.088e-145	493.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
DYD2_k127_3496334_3	330214.NIDE3500	1.876e-58	209.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DYD2_k127_3496334_4	391625.PPSIR1_09565	2.277e-48	179.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
DYD2_k127_3496334_1	414684.RC1_0235	7.7e-125	424.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2JPQC@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
DYD2_k127_3496334_2	1415780.JPOG01000001_gene961	9.501e-107	377.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,1X78Y@135614|Xanthomonadales	135614|Xanthomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
DYD2_k127_3496334_5	935866.JAER01000008_gene889	2.131e-32	134.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4DR5C@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
DYD2_k127_3496334_6	525904.Tter_1099	1.047e-14	83.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3502662_1	861299.J421_2338	3.089e-91	331.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277,ko:K07278	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
DYD2_k127_3502662_2	323261.Noc_1260	1.47e-63	235.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,1S5S8@1236|Gammaproteobacteria,1WYBG@135613|Chromatiales	135613|Chromatiales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
DYD2_k127_3502662_3	861299.J421_2559	2.988e-57	222.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
DYD2_k127_3502662_0	861299.J421_2560	1.678e-92	316.0	COG0533@1|root,COG0533@2|Bacteria,1ZT0P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
DYD2_k127_3506812_4	648996.Theam_0563	4.869e-06	49.0	COG1560@1|root,COG1560@2|Bacteria,2G44U@200783|Aquificae	200783|Aquificae	M	Lipid A biosynthesis	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
DYD2_k127_3506812_1	861299.J421_2674	3.091e-55	204.0	COG0463@1|root,COG0463@2|Bacteria,1ZTJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	Glycos_transf_2
DYD2_k127_3506812_2	861299.J421_1980	2.964e-43	179.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
DYD2_k127_3506812_0	861299.J421_2672	3.434e-104	365.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3506812_3	861299.J421_4201	3.556e-14	78.0	2CA00@1|root,344QM@2|Bacteria,1ZU1Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3506812_5	1123389.ATXJ01000002_gene1618	0.000307	45.0	COG1253@1|root,COG1253@2|Bacteria,1WI7Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DYD2_k127_3527052_0	478741.JAFS01000001_gene2213	2.363e-19	100.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	ndh	-	1.6.99.3,1.8.5.2	ko:K03885,ko:K16937	ko00190,ko00920,ko01120,map00190,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxD,DoxX,Pyr_redox_2
DYD2_k127_3610365_2	765952.PUV_20740	0.0009288	51.0	2DM90@1|root,327AV@2|Bacteria,2JGU4@204428|Chlamydiae	204428|Chlamydiae	S	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
DYD2_k127_3610365_1	861299.J421_0305	9.95e-45	183.0	COG1413@1|root,COG1413@2|Bacteria,1ZTU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DYD2_k127_3610365_0	861299.J421_0306	5.292e-88	307.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DYD2_k127_365867_8	190650.CC_3179	2.545e-86	306.0	COG2159@1|root,COG2159@2|Bacteria,1PTY1@1224|Proteobacteria,2V5RF@28211|Alphaproteobacteria,2KHVI@204458|Caulobacterales	204458|Caulobacterales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
DYD2_k127_365867_7	1210884.HG799476_gene15392	8.553e-104	349.0	COG3483@1|root,COG3483@2|Bacteria,2J412@203682|Planctomycetes	203682|Planctomycetes	E	Tryptophan 2,3-dioxygenase	-	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
DYD2_k127_365867_5	926549.KI421517_gene809	7.587e-118	410.0	COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47KM9@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid	kmo	-	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
DYD2_k127_365867_1	58123.JOFJ01000017_gene4197	1.879e-143	482.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria,4EH57@85012|Streptosporangiales	201174|Actinobacteria	E	Aminotransferase class-V	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
DYD2_k127_365867_2	215803.DB30_7173	7.848e-139	449.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,431I4@68525|delta/epsilon subdivisions,2WW88@28221|Deltaproteobacteria,2YYBM@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
DYD2_k127_365867_10	1502850.FG91_00780	6.139e-52	207.0	COG1917@1|root,COG1917@2|Bacteria,1QVVQ@1224|Proteobacteria,2TVET@28211|Alphaproteobacteria,2K5FZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
DYD2_k127_365867_13	502025.Hoch_5802	1.468e-07	62.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,PG_binding_1
DYD2_k127_365867_0	1254432.SCE1572_43170	6.654e-174	557.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZJK@68525|delta/epsilon subdivisions,2WZ3T@28221|Deltaproteobacteria,2Z19K@29|Myxococcales	28221|Deltaproteobacteria	C	COG1858 Cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
DYD2_k127_365867_11	1123073.KB899241_gene2426	7.263e-48	184.0	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,1S3QG@1236|Gammaproteobacteria,1X67A@135614|Xanthomonadales	135614|Xanthomonadales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DYD2_k127_365867_4	1123073.KB899241_gene2425	1.932e-120	424.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QU1S@1224|Proteobacteria,1T1MB@1236|Gammaproteobacteria,1X3A7@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
DYD2_k127_365867_6	1142394.PSMK_22080	8.349e-113	402.0	COG4232@1|root,COG4232@2|Bacteria,2IXJF@203682|Planctomycetes	203682|Planctomycetes	CO	Cytochrome c biogenesis protein transmembrane region	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
DYD2_k127_365867_3	502025.Hoch_0089	1.099e-126	416.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42T5F@68525|delta/epsilon subdivisions,2WQVP@28221|Deltaproteobacteria,2YU42@29|Myxococcales	28221|Deltaproteobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
DYD2_k127_365867_12	234267.Acid_4815	6.332e-31	130.0	COG3682@1|root,COG3682@2|Bacteria,3Y8BB@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
DYD2_k127_365867_9	861299.J421_1461	6.801e-53	208.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
DYD2_k127_3681911_1	1123368.AUIS01000004_gene281	3.412e-69	263.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Iron Permease	efeU_1	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
DYD2_k127_3681911_6	861299.J421_2549	7.12e-30	130.0	COG0791@1|root,COG0791@2|Bacteria,1ZTVR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
DYD2_k127_3681911_8	997346.HMPREF9374_0031	1.197e-07	55.0	COG3526@1|root,COG3526@2|Bacteria,1VKFI@1239|Firmicutes,4HR9S@91061|Bacilli	91061|Bacilli	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
DYD2_k127_3681911_4	861299.J421_3610	9.139e-34	133.0	COG0662@1|root,COG0662@2|Bacteria,1ZTKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
DYD2_k127_3681911_2	391625.PPSIR1_06551	1.925e-62	229.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
DYD2_k127_3681911_5	313596.RB2501_12297	3.269e-31	138.0	2EV7A@1|root,33NN1@2|Bacteria,4NZZD@976|Bacteroidetes,1I85R@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3681911_7	1279009.ADICEAN_02616	2.703e-14	84.0	COG4334@1|root,COG4334@2|Bacteria,4NSAC@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
DYD2_k127_3681911_3	502025.Hoch_1388	4.907e-59	215.0	COG0500@1|root,COG0500@2|Bacteria,1PDBA@1224|Proteobacteria,435FH@68525|delta/epsilon subdivisions,2WZT1@28221|Deltaproteobacteria,2Z2PI@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
DYD2_k127_3681911_0	1429916.X566_24255	5.165e-79	274.0	COG2267@1|root,COG2267@2|Bacteria,1PE1Z@1224|Proteobacteria,2U8Z2@28211|Alphaproteobacteria,3K63X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
DYD2_k127_3695904_0	1480694.DC28_10155	2.969e-145	477.0	COG0148@1|root,COG0148@2|Bacteria,2J59Y@203691|Spirochaetes	203691|Spirochaetes	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
DYD2_k127_3695904_3	1288963.ADIS_3309	6.222e-11	74.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,47MT6@768503|Cytophagia	976|Bacteroidetes	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
DYD2_k127_3695904_1	378806.STAUR_3769	9.974e-44	170.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2YVUS@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DYD2_k127_3695904_2	861299.J421_3009	2.962e-20	96.0	COG0611@1|root,COG0611@2|Bacteria,1ZTIU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
DYD2_k127_3696709_1	861299.J421_3316	1.34e-118	401.0	COG1066@1|root,COG1066@2|Bacteria,1ZSYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase
DYD2_k127_3696709_0	1209989.TepiRe1_2820	2.042e-136	475.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,42FJ3@68295|Thermoanaerobacterales	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
DYD2_k127_3696709_2	1379270.AUXF01000006_gene204	3.403e-65	230.0	COG1573@1|root,COG1573@2|Bacteria,1ZTG5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DYD2_k127_370584_2	345219.Bcoa_3211	2.749e-17	90.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus	91061|Bacilli	K	Cold shock	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DYD2_k127_370584_1	648996.Theam_1506	9.461e-19	89.0	COG1278@1|root,COG1278@2|Bacteria,2G4CP@200783|Aquificae	200783|Aquificae	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DYD2_k127_370584_0	861299.J421_2871	2.941e-103	347.0	COG0469@1|root,COG0469@2|Bacteria,1ZSMD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
DYD2_k127_371188_0	583355.Caka_1487	1.153e-101	362.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
DYD2_k127_371188_1	1038859.AXAU01000024_gene3998	3.382e-43	170.0	COG4772@1|root,COG4772@2|Bacteria,1MXJU@1224|Proteobacteria,2TRYT@28211|Alphaproteobacteria,3JU6N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
DYD2_k127_3714254_1	42256.RradSPS_0753	2.798e-46	175.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
DYD2_k127_3714254_2	298655.KI912266_gene158	1.279e-27	126.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
DYD2_k127_3714254_0	861299.J421_3246	4.13e-57	219.0	COG5617@1|root,COG5617@2|Bacteria,1ZUMG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
DYD2_k127_3724810_0	309807.SRU_2391	5.618e-61	235.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase
DYD2_k127_3734723_0	84531.JMTZ01000095_gene438	1.844e-155	506.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1X46E@135614|Xanthomonadales	135614|Xanthomonadales	L	Helicase	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DYD2_k127_3734723_2	566466.NOR53_491	2.686e-11	78.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C
DYD2_k127_3734723_1	861299.J421_1231	1.754e-43	183.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1231|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DYD2_k127_3766655_1	861299.J421_3071	2.022e-16	88.0	COG0769@1|root,COG0769@2|Bacteria,1ZSS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
DYD2_k127_3766655_0	861299.J421_3070	8.723e-103	364.0	COG0768@1|root,COG0768@2|Bacteria,1ZSYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
DYD2_k127_378145_2	309807.SRU_2815	2.046e-18	87.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	-	-	-	ko:K07172,ko:K18842	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
DYD2_k127_378145_1	163908.KB235896_gene4770	5.572e-29	124.0	COG3654@1|root,COG3654@2|Bacteria,1G6SU@1117|Cyanobacteria,1HSF9@1161|Nostocales	1117|Cyanobacteria	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
DYD2_k127_378145_0	502025.Hoch_1577	5.409e-61	231.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DYD2_k127_3792692_3	1232410.KI421412_gene336	0.0008381	44.0	29SGJ@1|root,2ZKKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3792692_2	1121085.AUCI01000002_gene4020	1.457e-08	59.0	2BFS6@1|root,329M0@2|Bacteria,1UBZZ@1239|Firmicutes,4INFW@91061|Bacilli,1ZNF2@1386|Bacillus	91061|Bacilli	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DYD2_k127_3792692_1	472759.Nhal_2208	3.33e-74	266.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1WW4N@135613|Chromatiales	135613|Chromatiales	C	PFAM aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DYD2_k127_3792692_0	595536.ADVE02000001_gene481	1.089e-99	332.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,2TSIG@28211|Alphaproteobacteria,36Z2V@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
DYD2_k127_3797797_3	596151.DesfrDRAFT_1827	5.724e-05	46.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WJYG@28221|Deltaproteobacteria,2M807@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
DYD2_k127_3797797_0	1407650.BAUB01000002_gene402	3.763e-86	292.0	COG1121@1|root,COG1121@2|Bacteria,1G2EJ@1117|Cyanobacteria,1H2EA@1129|Synechococcus	1117|Cyanobacteria	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
DYD2_k127_3797797_1	368407.Memar_0814	5.554e-73	264.0	COG1108@1|root,arCOG01006@2157|Archaea,2XTNB@28890|Euryarchaeota,2N9BQ@224756|Methanomicrobia	224756|Methanomicrobia	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	iAF692.Mbar_A0996	ABC-3
DYD2_k127_3797797_2	388467.A19Y_2739	3.687e-07	62.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	JAB,Prok-JAB
DYD2_k127_380964_1	880073.Calab_2383	2.907e-40	162.0	COG0739@1|root,COG0739@2|Bacteria,2NPG3@2323|unclassified Bacteria	2|Bacteria	M	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
DYD2_k127_380964_0	1232410.KI421415_gene3026	1.806e-165	546.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2X28Y@28221|Deltaproteobacteria,43U5A@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1
DYD2_k127_380964_2	523850.TON_0642	1.521e-09	70.0	COG2306@1|root,arCOG05760@2157|Archaea,2XX0W@28890|Euryarchaeota,243ZF@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF402)	-	-	-	ko:K09145	-	-	-	-	ko00000	-	-	-	DUF402
DYD2_k127_3837531_1	379066.GAU_1899	1.787e-99	337.0	COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
DYD2_k127_3837531_0	861299.J421_3468	2.671e-115	383.0	COG0484@1|root,COG0484@2|Bacteria,1ZSVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DYD2_k127_3837688_8	292459.STH2008	2.744e-11	78.0	28KG8@1|root,2ZA24@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_3837688_4	1121920.AUAU01000015_gene1138	1.04e-35	154.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
DYD2_k127_3837688_6	1267533.KB906739_gene2485	4.325e-27	124.0	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
DYD2_k127_3837688_2	448385.sce4361	2.509e-56	209.0	COG4912@1|root,COG4912@2|Bacteria,1RGNQ@1224|Proteobacteria,434G0@68525|delta/epsilon subdivisions,2X8VJ@28221|Deltaproteobacteria,2Z0JW@29|Myxococcales	28221|Deltaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
DYD2_k127_3837688_1	1227497.C491_14577	2.742e-59	226.0	COG3369@1|root,arCOG03175@1|root,arCOG03174@2157|Archaea,arCOG03175@2157|Archaea,2Y1YC@28890|Euryarchaeota,23ZKU@183963|Halobacteria	183963|Halobacteria	S	CDGSH-type zinc finger. Function unknown.	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
DYD2_k127_3837688_3	1385511.N783_03255	1.369e-38	160.0	COG0655@1|root,COG0655@2|Bacteria,1U9UK@1239|Firmicutes,4IK2B@91061|Bacilli,2YBPN@289201|Pontibacillus	91061|Bacilli	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
DYD2_k127_3837688_5	2074.JNYD01000001_gene6264	4.72e-34	135.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
DYD2_k127_3837688_0	1192034.CAP_1547	5.153e-132	439.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria,2YUQE@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439,ko:K13049	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DYD2_k127_3837688_7	861299.J421_1231	1.275e-26	126.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1231|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DYD2_k127_385175_2	189753.AXAS01000024_gene544	4.21e-48	180.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,3JXJE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
DYD2_k127_385175_0	309801.trd_0580	1.196e-136	444.0	COG1878@1|root,COG1878@2|Bacteria,2GBDZ@200795|Chloroflexi,27Z1S@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
DYD2_k127_385175_1	1173028.ANKO01000020_gene5535	1.868e-52	188.0	COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria,1HH6G@1150|Oscillatoriales	1117|Cyanobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
DYD2_k127_3854052_1	861299.J421_2641	2.342e-41	165.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
DYD2_k127_3854052_0	880074.BARVI_08660	4.117e-46	183.0	COG3392@1|root,COG3392@2|Bacteria,4NJNW@976|Bacteroidetes,2FRYH@200643|Bacteroidia,22YFJ@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
DYD2_k127_3864926_2	861299.J421_3592	2.029e-61	225.0	COG0613@1|root,COG0613@2|Bacteria,1ZTHM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
DYD2_k127_3864926_0	1123284.KB899045_gene2557	8.99e-87	304.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,26NMP@186821|Sporolactobacillaceae	91061|Bacilli	C	FAD dependent oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_3864926_6	1379270.AUXF01000003_gene3855	1.524e-39	153.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
DYD2_k127_3864926_3	1125863.JAFN01000001_gene1846	4.145e-54	203.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
DYD2_k127_3864926_1	290397.Adeh_1049	5.349e-77	282.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
DYD2_k127_3864926_4	1125863.JAFN01000001_gene3382	2.655e-44	177.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
DYD2_k127_3864926_5	525904.Tter_0400	1.384e-42	172.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
DYD2_k127_3876370_2	645512.GCWU000246_00060	1.824e-19	93.0	COG0816@1|root,COG0816@2|Bacteria,3TBFG@508458|Synergistetes	508458|Synergistetes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
DYD2_k127_3876370_0	379066.GAU_0793	3.609e-135	444.0	COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
DYD2_k127_3876370_1	379066.GAU_0644	3.306e-41	158.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DYD2_k127_3890746_0	494419.ALPM01000021_gene86	4.731e-06	59.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
DYD2_k127_3927104_1	321327.CYA_1559	3.701e-128	418.0	COG2046@1|root,COG2046@2|Bacteria,1G0E8@1117|Cyanobacteria,1GZIH@1129|Synechococcus	1117|Cyanobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
DYD2_k127_3927104_0	1260251.SPISAL_06070	2.746e-152	501.0	COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WXUN@135613|Chromatiales	135613|Chromatiales	P	TrkA-C domain	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
DYD2_k127_3927104_3	498848.TaqDRAFT_3787	8.95e-59	209.0	COG4636@1|root,COG4636@2|Bacteria,1WJWU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DYD2_k127_3927104_2	1379270.AUXF01000001_gene2386	3.283e-64	227.0	COG1896@1|root,COG1896@2|Bacteria,1ZU77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
DYD2_k127_395903_0	107635.AZUO01000001_gene3356	5.289e-260	814.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,36X8N@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
DYD2_k127_3960232_1	511051.CSE_12980	8.341e-41	174.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
DYD2_k127_3960232_0	382464.ABSI01000011_gene2473	3.302e-50	205.0	COG0028@1|root,COG1404@1|root,COG2885@1|root,COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3507@1|root,COG4733@1|root,COG4935@1|root,COG5295@1|root,COG0028@2|Bacteria,COG1404@2|Bacteria,COG2885@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3507@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,COG5295@2|Bacteria,46W6Z@74201|Verrucomicrobia	2|Bacteria	GMOU	Fibronectin type 3 domain	-	-	3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3	ko:K01179,ko:K01361,ko:K01637,ko:K01729,ko:K09942,ko:K20276	ko00051,ko00500,ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00051,map00500,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479,R03706,R06200,R11307,R11308	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	GH5,GH9	-	fn3
DYD2_k127_3960232_2	1298863.AUEP01000005_gene2571	2.903e-06	61.0	COG3291@1|root,COG4247@1|root,COG3291@2|Bacteria,COG4247@2|Bacteria,2GJDY@201174|Actinobacteria	201174|Actinobacteria	I	Phytase	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
DYD2_k127_3967300_1	861299.J421_2420	1.098e-23	108.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DYD2_k127_3967300_0	937777.Deipe_2373	2.107e-37	156.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
DYD2_k127_3975270_1	502025.Hoch_6598	2.091e-56	202.0	COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,4392A@68525|delta/epsilon subdivisions,2X47Z@28221|Deltaproteobacteria,2YYG2@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_3975270_3	671143.DAMO_0456	4.838e-18	89.0	COG1153@1|root,COG1153@2|Bacteria	2|Bacteria	C	PFAM molydopterin dinucleotide-binding region	-	-	1.2.7.12,1.6.5.3	ko:K00203,ko:K00336	ko00190,ko00680,ko01100,ko01120,ko01200,map00190,map00680,map01100,map01120,map01200	M00144,M00567	R03015,R08060,R11743,R11945	RC00061,RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
DYD2_k127_3975270_0	891968.Anamo_1144	2.752e-141	469.0	COG1029@1|root,COG1029@2|Bacteria,3TBWP@508458|Synergistetes	508458|Synergistetes	C	Molybdopterin oxidoreductase	-	-	1.2.7.12	ko:K00201	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdopterin
DYD2_k127_3975270_2	1380390.JIAT01000010_gene4326	1.091e-55	197.0	COG1229@1|root,COG1229@2|Bacteria	2|Bacteria	C	Formylmethanofuran dehydrogenase subunit A	fhcA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
DYD2_k127_399185_1	498761.HM1_1710	1.153e-35	141.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia	186801|Clostridia	G	peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
DYD2_k127_399185_0	383372.Rcas_3716	1.365e-64	234.0	COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi,3766W@32061|Chloroflexia	32061|Chloroflexia	EQ	PFAM peptidase S58, DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
DYD2_k127_399185_2	1173028.ANKO01000116_gene5724	2.068e-30	126.0	COG0546@1|root,COG0546@2|Bacteria,1G6AW@1117|Cyanobacteria,1HCZI@1150|Oscillatoriales	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
DYD2_k127_40006_1	264732.Moth_1850	5.985e-59	213.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
DYD2_k127_40006_0	1121468.AUBR01000021_gene2825	8.509e-241	780.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,42HS1@68295|Thermoanaerobacterales	186801|Clostridia	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
DYD2_k127_40006_2	379066.GAU_2229	2.03e-09	68.0	2960H@1|root,2ZTB5@2|Bacteria,1ZU7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4022299_1	316067.Geob_0052	2.794e-45	169.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria,43UR2@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
DYD2_k127_4022299_0	1089550.ATTH01000001_gene2547	2.854e-156	512.0	COG1757@1|root,COG1757@2|Bacteria,4NHP9@976|Bacteroidetes,1FIXG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
DYD2_k127_4027628_2	710696.Intca_0096	5.577e-115	374.0	COG0189@1|root,COG0189@2|Bacteria,2I75I@201174|Actinobacteria,4FEMX@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
DYD2_k127_4027628_4	1380393.JHVP01000005_gene3586	5.601e-48	192.0	COG3340@1|root,COG3340@2|Bacteria,2IGG2@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
DYD2_k127_4027628_0	1121385.AQXW01000004_gene2651	7.448e-123	406.0	COG2382@1|root,COG2382@2|Bacteria,2I844@201174|Actinobacteria	201174|Actinobacteria	P	Esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
DYD2_k127_4027628_1	1869.MB27_35725	6.339e-117	392.0	COG1181@1|root,COG1181@2|Bacteria,2HP1M@201174|Actinobacteria,4DHKT@85008|Micromonosporales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C
DYD2_k127_4027628_3	1380393.JHVP01000005_gene3591	6.364e-92	308.0	COG4947@1|root,COG4947@2|Bacteria,2I9H9@201174|Actinobacteria,4EWIE@85013|Frankiales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
DYD2_k127_4027628_5	761193.Runsl_0782	2.139e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,4NJ1F@976|Bacteroidetes,47NCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
DYD2_k127_4052994_0	309807.SRU_0349	2.639e-119	394.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
DYD2_k127_4052994_2	35754.JNYJ01000101_gene9934	7.757e-76	262.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria,4DDTQ@85008|Micromonosporales	201174|Actinobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
DYD2_k127_4052994_1	1183438.GKIL_3395	2.727e-113	381.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DYD2_k127_406546_1	373903.Hore_11130	3.413e-177	577.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3WAEZ@53433|Halanaerobiales	186801|Clostridia	S	PFAM OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
DYD2_k127_406546_0	379066.GAU_1492	4.957e-319	997.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
DYD2_k127_4080615_4	521674.Plim_3498	4.73e-24	118.0	COG0247@1|root,COG0247@2|Bacteria,2IXBR@203682|Planctomycetes	203682|Planctomycetes	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
DYD2_k127_4080615_0	1146883.BLASA_0208	5.43e-108	379.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4EU3Z@85013|Frankiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
DYD2_k127_4080615_5	1123508.JH636440_gene2572	2.071e-15	89.0	COG4319@1|root,COG4319@2|Bacteria,2J3B0@203682|Planctomycetes	203682|Planctomycetes	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
DYD2_k127_4080615_2	1341151.ASZU01000006_gene2798	2.743e-46	180.0	COG1073@1|root,COG1073@2|Bacteria,1V1RV@1239|Firmicutes,4HGDR@91061|Bacilli,27B3I@186824|Thermoactinomycetaceae	91061|Bacilli	S	alpha/beta hydrolase fold	M1-904	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
DYD2_k127_4080615_1	379066.GAU_1721	1.105e-96	352.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
DYD2_k127_4080615_3	1379270.AUXF01000006_gene168	3.773e-41	171.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DYD2_k127_408645_1	314230.DSM3645_11177	7.519e-32	141.0	COG0241@1|root,COG0241@2|Bacteria,2IZYR@203682|Planctomycetes	203682|Planctomycetes	E	Polynucleotide kinase 3 phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
DYD2_k127_408645_0	1525715.IX54_07415	8.411e-117	392.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,2PWCP@265|Paracoccus	28211|Alphaproteobacteria	E	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
DYD2_k127_4103870_3	67352.JODS01000015_gene7031	1.723e-08	58.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DYD2_k127_4103870_0	1123393.KB891316_gene2018	7.16e-123	401.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4103870_1	1214242.B446_31610	7.592e-66	235.0	COG0431@1|root,COG0431@2|Bacteria,2IFRY@201174|Actinobacteria	201174|Actinobacteria	S	NAD(P)H-dependent FMN reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
DYD2_k127_4103870_2	1120973.AQXL01000095_gene246	3.062e-29	126.0	COG2151@1|root,COG2151@2|Bacteria,1VE3S@1239|Firmicutes,4HKP6@91061|Bacilli	91061|Bacilli	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
DYD2_k127_4112043_3	1267534.KB906758_gene2182	8.225e-27	117.0	2DEWU@1|root,2ZPJP@2|Bacteria,3Y585@57723|Acidobacteria,2JJN8@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4112043_7	1439940.BAY1663_01113	4.3e-10	71.0	COG2199@1|root,COG3706@2|Bacteria,1MZQ8@1224|Proteobacteria,1RS4B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	yneF	-	2.7.7.65	ko:K21020	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,MASE1
DYD2_k127_4112043_5	526225.Gobs_0076	5.03e-20	104.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4EX4S@85013|Frankiales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_4,PAS_9
DYD2_k127_4112043_0	309807.SRU_1342	2.667e-73	256.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DYD2_k127_4112043_1	1356852.N008_11770	1.91e-41	173.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47JJK@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DYD2_k127_4112043_6	1117319.PSPO_11296	7.528e-19	102.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,2Q0ZC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
DYD2_k127_4112043_4	1122137.AQXF01000004_gene1692	7.433e-26	113.0	COG3795@1|root,COG3795@2|Bacteria,1NJ4J@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
DYD2_k127_411538_5	448385.sce6976	7.117e-39	164.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
DYD2_k127_411538_0	926569.ANT_31720	1.329e-275	880.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
DYD2_k127_411538_3	69279.BG36_05170	3.741e-101	359.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2TSA1@28211|Alphaproteobacteria,43I4W@69277|Phyllobacteriaceae	1224|Proteobacteria	Q	imidazolonepropionase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
DYD2_k127_411538_2	584708.Apau_0124	4.924e-108	368.0	COG3643@1|root,COG3643@2|Bacteria,3TA3X@508458|Synergistetes	508458|Synergistetes	E	Formiminotransferase domain, N-terminal subdomain	-	-	-	-	-	-	-	-	-	-	-	-	FTCD,FTCD_N
DYD2_k127_411538_8	869210.Marky_2005	3.749e-05	51.0	COG1937@1|root,COG1937@2|Bacteria,1WN9E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
DYD2_k127_411538_1	240015.ACP_3026	9.5e-153	500.0	COG2986@1|root,COG2986@2|Bacteria,3Y3YW@57723|Acidobacteria,2JIK6@204432|Acidobacteriia	204432|Acidobacteriia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
DYD2_k127_411538_6	584708.Apau_0125	4.479e-34	144.0	COG3404@1|root,COG3404@2|Bacteria,3TBGK@508458|Synergistetes	508458|Synergistetes	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
DYD2_k127_411538_4	1121439.dsat_2228	3.75e-66	240.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WPYW@28221|Deltaproteobacteria,2MC7X@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_4115973_0	713587.THITH_10875	1.521e-129	425.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DYD2_k127_4115973_2	1123360.thalar_00960	7.102e-39	153.0	29681@1|root,2ZTI1@2|Bacteria,1RA8W@1224|Proteobacteria,2U6CU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
DYD2_k127_4115973_1	298653.Franean1_3855	1.548e-40	168.0	COG0515@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,2IBPU@201174|Actinobacteria,4EU2Z@85013|Frankiales	201174|Actinobacteria	KLT	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_3,GGDEF,Guanylate_cyc,HisKA_3,Pkinase
DYD2_k127_4143508_2	861299.J421_4487	8.093e-77	272.0	COG3595@1|root,COG3595@2|Bacteria,1ZTJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
DYD2_k127_4143508_1	118173.KB235914_gene2665	8.273e-79	269.0	COG1611@1|root,COG1611@2|Bacteria,1G0YF@1117|Cyanobacteria,1HF8H@1150|Oscillatoriales	1117|Cyanobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
DYD2_k127_4143508_0	290397.Adeh_0386	3.745e-105	365.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
DYD2_k127_4143508_3	543913.D521_1096	7.99e-38	145.0	COG0537@1|root,COG0537@2|Bacteria,1N3EA@1224|Proteobacteria,2VSGA@28216|Betaproteobacteria	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
DYD2_k127_4143508_4	105420.BBPO01000086_gene4922	1.717e-07	58.0	COG3291@1|root,COG3291@2|Bacteria,2HHTF@201174|Actinobacteria,2NHQJ@228398|Streptacidiphilus	201174|Actinobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Phosphoesterase,fn3
DYD2_k127_4150085_1	925409.KI911562_gene2753	1.673e-78	273.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1IQGT@117747|Sphingobacteriia	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
DYD2_k127_4150085_0	861299.J421_3048	1.703e-317	1002.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
DYD2_k127_4152341_2	404380.Gbem_0838	6.826e-30	138.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
DYD2_k127_4152341_1	861299.J421_3213	1.757e-95	343.0	COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
DYD2_k127_4152341_0	861299.J421_3212	1.309e-148	482.0	COG1190@1|root,COG1190@2|Bacteria,1ZT9X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
DYD2_k127_4167449_4	717605.Theco_2671	6.643e-97	326.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H9WM@91061|Bacilli,26SPY@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
DYD2_k127_4167449_1	379066.GAU_0818	1.14e-165	550.0	COG0554@1|root,COG0554@2|Bacteria,1ZTX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
DYD2_k127_4167449_7	338963.Pcar_2033	1.718e-24	120.0	COG1611@1|root,COG1611@2|Bacteria,1RJ91@1224|Proteobacteria,42TR7@68525|delta/epsilon subdivisions,2WQUE@28221|Deltaproteobacteria,43VC6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A,Lysine_decarbox
DYD2_k127_4167449_3	1183438.GKIL_3353	1.787e-99	342.0	COG2008@1|root,COG2008@2|Bacteria,1G4PN@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DYD2_k127_4167449_8	1266908.AQPB01000029_gene2110	9.764e-21	96.0	COG1872@1|root,COG1872@2|Bacteria,1QKJ0@1224|Proteobacteria,1SDPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
DYD2_k127_4167449_2	379066.GAU_1084	2.571e-142	467.0	COG0477@1|root,COG2814@2|Bacteria,1ZTDQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
DYD2_k127_4167449_5	518766.Rmar_1623	8.198e-87	312.0	COG3291@1|root,COG3291@2|Bacteria,4PMYH@976|Bacteroidetes	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
DYD2_k127_4167449_0	861299.J421_1132	6.569e-187	594.0	COG0673@1|root,COG0673@2|Bacteria,1ZSVT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
DYD2_k127_4167449_6	926549.KI421517_gene3612	3.226e-54	194.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,47MR9@768503|Cytophagia	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
DYD2_k127_4181709_3	477641.MODMU_4420	3.635e-16	84.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4ESVE@85013|Frankiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
DYD2_k127_4181709_0	1379270.AUXF01000003_gene3580	5.126e-151	494.0	COG0541@1|root,COG0541@2|Bacteria,1ZSPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
DYD2_k127_4181709_2	338963.Pcar_0547	1.091e-83	295.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X5YU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
DYD2_k127_4181709_1	59374.Fisuc_1627	1.388e-126	418.0	COG0104@1|root,COG0104@2|Bacteria	2|Bacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889	Adenylsucc_synt
DYD2_k127_4181709_4	861299.J421_2804	1.351e-06	52.0	COG0329@1|root,COG0329@2|Bacteria,1ZTGV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
DYD2_k127_4183351_0	251221.35214032	6.994e-133	438.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
DYD2_k127_4183351_1	861299.J421_4071	9.372e-26	115.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DYD2_k127_4210810_0	1089550.ATTH01000001_gene1477	2.713e-189	604.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
DYD2_k127_4210810_7	1408224.SAMCCGM7_c4409	6.449e-08	65.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BAVP@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16
DYD2_k127_4210810_1	861299.J421_1661	3.898e-164	531.0	COG0534@1|root,COG0534@2|Bacteria,1ZUGI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
DYD2_k127_4210810_4	661478.OP10G_3171	4.34e-52	209.0	COG2249@1|root,COG2249@2|Bacteria	2|Bacteria	K	NAD(P)H dehydrogenase (quinone) activity	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
DYD2_k127_4210810_3	251221.35211157	1.439e-64	238.0	COG2367@1|root,COG2367@2|Bacteria,1G1KE@1117|Cyanobacteria	1117|Cyanobacteria	V	Beta-lactamase class A	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
DYD2_k127_4210810_2	414684.RC1_0645	1.923e-81	287.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria,2JR4R@204441|Rhodospirillales	204441|Rhodospirillales	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
DYD2_k127_4210810_6	204669.Acid345_1594	2.605e-29	126.0	COG0457@1|root,COG0457@2|Bacteria,3Y4VN@57723|Acidobacteria,2JJG5@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
DYD2_k127_4210810_5	1394176.AWUO01000001_gene1368	1.109e-33	140.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DYD2_k127_4246475_0	1521187.JPIM01000142_gene2782	1.175e-288	911.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
DYD2_k127_4246475_1	1128421.JAGA01000003_gene2924	6.261e-55	204.0	2CAZH@1|root,2Z7RU@2|Bacteria,2NRIS@2323|unclassified Bacteria	2|Bacteria	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
DYD2_k127_4253062_0	861299.J421_3569	2.406e-105	349.0	COG0677@1|root,COG0677@2|Bacteria,1ZT42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
DYD2_k127_4253062_2	1379270.AUXF01000003_gene3651	4.459e-35	143.0	COG0741@1|root,COG0741@2|Bacteria,1ZTV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
DYD2_k127_4253062_1	314285.KT71_16136	2.116e-46	175.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1J7VU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
DYD2_k127_4253062_3	861299.J421_3797	8.193e-05	51.0	COG0470@1|root,COG0470@2|Bacteria,1ZT21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
DYD2_k127_4259599_3	266117.Rxyl_1936	6.332e-31	130.0	COG4424@1|root,COG4424@2|Bacteria,2GMCB@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
DYD2_k127_4259599_0	1089551.KE386572_gene4426	1.19e-80	292.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,2U12I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
DYD2_k127_4259599_1	1380347.JNII01000006_gene1268	9.154e-55	205.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4ESNA@85013|Frankiales	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
DYD2_k127_4259599_2	388413.ALPR1_00680	1.45e-45	167.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Phytase-like
DYD2_k127_427275_2	861299.J421_0541	1.034e-18	89.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	ycbU	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DYD2_k127_427275_4	379066.GAU_2624	0.0009015	46.0	COG1225@1|root,COG1225@2|Bacteria,1ZUGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DYD2_k127_427275_1	379066.GAU_2624	5.083e-24	105.0	COG1225@1|root,COG1225@2|Bacteria,1ZUGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DYD2_k127_427275_0	861299.J421_1716	1.368e-37	147.0	COG0526@1|root,COG0526@2|Bacteria,1ZTV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DYD2_k127_427275_3	946362.XP_004987829.1	0.0001991	51.0	KOG2524@1|root,KOG2524@2759|Eukaryota,38KFD@33154|Opisthokonta	33154|Opisthokonta	H	tRNA modification	C9orf64	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008477,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016798,GO:0016799,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0101030,GO:1901360	-	-	-	-	-	-	-	-	-	-	Q_salvage
DYD2_k127_4279920_2	1122137.AQXF01000003_gene2416	4.877e-41	156.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2UGES@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
DYD2_k127_4279920_1	296591.Bpro_1826	2.754e-49	191.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VJF9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
DYD2_k127_4279920_0	269799.Gmet_0138	1.236e-135	447.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
DYD2_k127_4279920_6	1236689.MMALV_07010	2.265e-05	56.0	COG0697@1|root,arCOG00271@2157|Archaea,2XTYP@28890|Euryarchaeota,3F2W2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD2_k127_4279920_3	1234364.AMSF01000021_gene1260	9.418e-22	105.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
DYD2_k127_4279920_5	1379270.AUXF01000001_gene2633	2.012e-06	57.0	2F756@1|root,33ZKP@2|Bacteria,1ZU38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4288524_0	861299.J421_0477	6.671e-100	339.0	COG0859@1|root,COG0859@2|Bacteria,1ZT3G@142182|Gemmatimonadetes	2|Bacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	opsX	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02841,ko:K02843,ko:K02849,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
DYD2_k127_4288524_8	322710.Avin_30000	2.805e-25	123.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
DYD2_k127_4288524_6	309807.SRU_2798	2.285e-40	156.0	COG0454@1|root,COG0456@2|Bacteria,4NT3M@976|Bacteroidetes,1FK4C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD2_k127_4288524_5	1384056.N787_02540	2.054e-43	160.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,1SAWR@1236|Gammaproteobacteria,1X80M@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
DYD2_k127_4288524_11	1227484.C471_09075	7.653e-07	56.0	arCOG10130@1|root,arCOG10130@2157|Archaea,2XZWX@28890|Euryarchaeota,23Y13@183963|Halobacteria	183963|Halobacteria	S	metal-sulfur cluster biosynthetic enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4288524_7	485913.Krac_12220	8.427e-37	151.0	COG3396@1|root,COG3396@2|Bacteria,2G9KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
DYD2_k127_4288524_10	1198232.CYCME_2337	1.202e-09	66.0	COG3460@1|root,COG3460@2|Bacteria,1ND92@1224|Proteobacteria	1224|Proteobacteria	Q	Phenylacetic acid degradation B	-	-	-	-	-	-	-	-	-	-	-	-	PaaB
DYD2_k127_4288524_2	452637.Oter_0067	2.758e-65	235.0	COG3279@1|root,COG3279@2|Bacteria,46VCX@74201|Verrucomicrobia,3KA2E@414999|Opitutae	2|Bacteria	K	PFAM response regulator receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	EAL,HATPase_c,HisKA,LytTR,Response_reg
DYD2_k127_4288524_4	452637.Oter_2330	2.895e-54	213.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
DYD2_k127_4288524_3	861299.J421_0735	1.893e-54	212.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_0735|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	-
DYD2_k127_4288524_9	1131812.JQMS01000001_gene2169	5.894e-18	98.0	COG1680@1|root,COG2976@1|root,COG1680@2|Bacteria,COG2976@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2NT82@237|Flavobacterium	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2,TPR_8
DYD2_k127_4288524_1	67352.JODS01000015_gene7031	6.88e-68	241.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DYD2_k127_4298773_0	861299.J421_2423	2e-323	1011.0	COG0495@1|root,COG0495@2|Bacteria,1ZSXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
DYD2_k127_4298773_2	379066.GAU_0167	2.367e-17	85.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
DYD2_k127_4298773_3	1123072.AUDH01000003_gene941	3.601e-10	74.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,2U85S@28211|Alphaproteobacteria,2JTFP@204441|Rhodospirillales	204441|Rhodospirillales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_4298773_1	861299.J421_2658	2.795e-71	260.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
DYD2_k127_4302805_6	546271.Selsp_1899	5.473e-83	288.0	COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4H20D@909932|Negativicutes	909932|Negativicutes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
DYD2_k127_4302805_0	861299.J421_3257	2.135e-244	766.0	COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
DYD2_k127_4302805_16	1120983.KB894573_gene350	1.741e-06	53.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,1JND7@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DYD2_k127_4302805_8	1122603.ATVI01000009_gene2496	4.746e-38	150.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,1X3JD@135614|Xanthomonadales	135614|Xanthomonadales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
DYD2_k127_4302805_15	675635.Psed_1360	4.394e-07	53.0	COG0778@1|root,COG0778@2|Bacteria,2GM9M@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
DYD2_k127_4302805_14	665571.STHERM_c17580	6.174e-14	84.0	COG0778@1|root,COG0778@2|Bacteria,2J8VG@203691|Spirochaetes	203691|Spirochaetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
DYD2_k127_4302805_4	861299.J421_3262	2.322e-98	339.0	COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
DYD2_k127_4302805_13	861299.J421_3263	4.075e-21	102.0	COG0586@1|root,COG0586@2|Bacteria,1ZTVI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
DYD2_k127_4302805_7	861299.J421_3264	7.519e-44	174.0	COG0245@1|root,COG0245@2|Bacteria,1ZTM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
DYD2_k127_4302805_10	926567.TheveDRAFT_1038	2.635e-31	142.0	COG0041@1|root,COG0041@2|Bacteria,3TB8R@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
DYD2_k127_4302805_3	379066.GAU_1632	3.284e-113	388.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DYD2_k127_4302805_2	1379270.AUXF01000006_gene256	2.153e-133	454.0	COG1060@1|root,COG1060@2|Bacteria,1ZSRJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
DYD2_k127_4302805_1	1121468.AUBR01000030_gene1226	9.265e-146	475.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
DYD2_k127_4302805_12	472175.EL18_01579	6.648e-26	109.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria,43KPN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DYD2_k127_4302805_5	861299.J421_3270	1.465e-90	304.0	COG1028@1|root,COG1028@2|Bacteria,1ZT4H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
DYD2_k127_4302805_11	290397.Adeh_2749	1.387e-28	119.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,2YU16@29|Myxococcales	28221|Deltaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
DYD2_k127_4308405_11	309807.SRU_1822	9.87e-06	48.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1FJG7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
DYD2_k127_4308405_0	379066.GAU_1112	1.151e-115	394.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
DYD2_k127_4308405_9	1238182.C882_2602	5.388e-21	96.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,2JT9R@204441|Rhodospirillales	204441|Rhodospirillales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
DYD2_k127_4308405_3	1379270.AUXF01000005_gene387	2.416e-73	252.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
DYD2_k127_4308405_10	1379270.AUXF01000005_gene388	5.404e-18	90.0	29142@1|root,2ZNRG@2|Bacteria,1ZV6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4308405_4	717231.Flexsi_0290	2.024e-66	232.0	COG1100@1|root,COG1100@2|Bacteria,2GEYH@200930|Deferribacteres	200930|Deferribacteres	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
DYD2_k127_4308405_6	1379270.AUXF01000005_gene391	5.563e-37	147.0	COG0558@1|root,COG0558@2|Bacteria,1ZSXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
DYD2_k127_4308405_7	292564.Cyagr_2072	1.831e-36	149.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1G0IZ@1117|Cyanobacteria,22RSP@167375|Cyanobium	1117|Cyanobacteria	S	CinA-like protein	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
DYD2_k127_4308405_5	768706.Desor_2272	1.632e-45	180.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,262Q7@186807|Peptococcaceae	186801|Clostridia	I	Lysophospholipase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
DYD2_k127_4308405_8	861299.J421_2889	7.276e-29	125.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
DYD2_k127_4308405_2	861299.J421_2890	8.374e-111	379.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
DYD2_k127_4308405_12	675817.VDA_001152	0.0003758	51.0	COG3637@1|root,COG3637@2|Bacteria,1RHUP@1224|Proteobacteria,1RY1S@1236|Gammaproteobacteria,1Y32A@135623|Vibrionales	135623|Vibrionales	M	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943,OMP_b-brl
DYD2_k127_4308405_1	1379270.AUXF01000005_gene399	7.198e-113	374.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
DYD2_k127_4329657_1	502025.Hoch_5038	1.411e-102	345.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,42Z17@68525|delta/epsilon subdivisions,2WURE@28221|Deltaproteobacteria,2YUPJ@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
DYD2_k127_4329657_2	760117.JN27_11565	3.475e-75	263.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2VHKV@28216|Betaproteobacteria,477MQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
DYD2_k127_4329657_3	1125863.JAFN01000001_gene381	7.968e-53	206.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
DYD2_k127_4329657_0	502025.Hoch_6851	4.516e-178	572.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2X9B9@28221|Deltaproteobacteria,2YX2A@29|Myxococcales	28221|Deltaproteobacteria	P	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
DYD2_k127_4329657_4	1282360.ABAC460_20815	5.333e-08	65.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2TRTV@28211|Alphaproteobacteria,2KH40@204458|Caulobacterales	204458|Caulobacterales	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
DYD2_k127_4334859_0	1254432.SCE1572_49580	1.22e-162	529.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YU0V@29|Myxococcales	28221|Deltaproteobacteria	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
DYD2_k127_4337717_0	246197.MXAN_6639	5.279e-121	412.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	2.3.1.233	ko:K16167,ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
DYD2_k127_4337717_1	1232410.KI421412_gene150	3.749e-118	386.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,43SZD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
DYD2_k127_4352058_2	935948.KE386495_gene1426	4.595e-35	139.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,42FN3@68295|Thermoanaerobacterales	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
DYD2_k127_4352058_0	861299.J421_2803	8.438e-131	435.0	COG2805@1|root,COG2805@2|Bacteria,1ZT2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DYD2_k127_4352058_1	1379270.AUXF01000004_gene3003	3.155e-57	224.0	COG0329@1|root,COG0329@2|Bacteria,1ZTGV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
DYD2_k127_435360_1	443143.GM18_1230	5.152e-92	308.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
DYD2_k127_435360_0	585199.HMPREF0577_1839	3.026e-137	446.0	COG1740@1|root,COG1740@2|Bacteria,2GKF2@201174|Actinobacteria	201174|Actinobacteria	C	Small subunit	hoxK	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
DYD2_k127_4379232_0	483219.LILAB_01635	6.089e-24	109.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
DYD2_k127_4379232_1	231434.JQJH01000001_gene1772	3.574e-10	72.0	COG0596@1|root,COG0596@2|Bacteria,1MVTG@1224|Proteobacteria,2TSZR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
DYD2_k127_441102_1	371042.NG99_19325	4.653e-07	63.0	COG0726@1|root,COG0726@2|Bacteria,1R4MK@1224|Proteobacteria,1RZCJ@1236|Gammaproteobacteria,3X73E@551|Erwinia	1236|Gammaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DYD2_k127_441102_0	1237149.C900_03194	6.084e-101	340.0	COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DYD2_k127_4435617_0	379066.GAU_0593	2.339e-188	602.0	COG1239@1|root,COG1239@2|Bacteria,1ZT0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
DYD2_k127_4435617_4	1047013.AQSP01000133_gene2114	2.802e-05	56.0	COG3391@1|root,COG3391@2|Bacteria,2NQ4G@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TolB_like
DYD2_k127_4435617_1	1379270.AUXF01000005_gene646	5.265e-129	422.0	COG2070@1|root,COG2070@2|Bacteria,1ZUN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
DYD2_k127_4435617_3	379066.GAU_1377	1.45e-34	146.0	COG2050@1|root,COG2050@2|Bacteria,1ZV1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
DYD2_k127_4435617_2	1125863.JAFN01000001_gene1707	3.794e-92	319.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
DYD2_k127_4436636_0	518766.Rmar_0669	2.194e-36	158.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1FJ16@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
DYD2_k127_4436636_1	1380763.BG53_15830	1.734e-33	134.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HGZ2@91061|Bacilli,26SJY@186822|Paenibacillaceae	91061|Bacilli	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
DYD2_k127_4437196_1	1279017.AQYJ01000026_gene187	6.277e-43	165.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,464PB@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750	OMPdecase
DYD2_k127_4437196_0	338966.Ppro_2629	1.791e-87	310.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
DYD2_k127_4437196_2	644282.Deba_2876	2.834e-37	150.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
DYD2_k127_4463734_1	926566.Terro_3894	0.0005921	45.0	COG3847@1|root,COG3847@2|Bacteria,3Y5Y3@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
DYD2_k127_4463734_0	404589.Anae109_0939	1.052e-129	424.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
DYD2_k127_4474515_0	314230.DSM3645_25562	4.854e-121	411.0	COG0248@1|root,COG0248@2|Bacteria,2IYSV@203682|Planctomycetes	203682|Planctomycetes	FP	Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
DYD2_k127_4492372_0	861299.J421_3362	4.148e-55	207.0	COG0159@1|root,COG0159@2|Bacteria,1ZSYU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
DYD2_k127_4492372_1	1379270.AUXF01000006_gene167	3.322e-35	136.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_4541762_1	861299.J421_1804	3.004e-77	270.0	COG0730@1|root,COG0730@2|Bacteria,1ZU67@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
DYD2_k127_4541762_3	309807.SRU_1978	5.79e-26	125.0	COG1538@1|root,COG1538@2|Bacteria,4NE4S@976|Bacteroidetes,1FJVV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DYD2_k127_4541762_2	517418.Ctha_2707	5.343e-32	138.0	COG0845@1|root,COG0845@2|Bacteria,1FE89@1090|Chlorobi	1090|Chlorobi	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
DYD2_k127_4541762_0	290318.Cvib_1642	2.774e-197	636.0	COG0841@1|root,COG0841@2|Bacteria,1FDJ5@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DYD2_k127_4546353_0	1379270.AUXF01000003_gene3384	6.128e-106	358.0	COG1253@1|root,COG1253@2|Bacteria,1ZT0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
DYD2_k127_4546353_1	886293.Sinac_2872	1.447e-80	297.0	COG1446@1|root,COG1446@2|Bacteria,2IZ4V@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2,DUF4440
DYD2_k127_4546353_2	1379270.AUXF01000001_gene2783	2.802e-69	263.0	COG0457@1|root,COG0457@2|Bacteria,1ZSYB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
DYD2_k127_4559275_3	861299.J421_0084	1.844e-59	234.0	COG0204@1|root,COG0204@2|Bacteria,1ZSY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
DYD2_k127_4559275_2	1304885.AUEY01000011_gene1761	7.294e-100	362.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2WINT@28221|Deltaproteobacteria,2MIZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
DYD2_k127_4559275_1	1379698.RBG1_1C00001G0629	2.728e-184	615.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
DYD2_k127_4559275_0	240015.ACP_2022	0.0	1168.0	COG1048@1|root,COG1048@2|Bacteria,3Y34Q@57723|Acidobacteria,2JHMV@204432|Acidobacteriia	204432|Acidobacteriia	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
DYD2_k127_4572023_4	861299.J421_0897	4.263e-37	146.0	COG0031@1|root,COG0031@2|Bacteria,1ZTA6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EK	Domain in cystathionine beta-synthase and other proteins.	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
DYD2_k127_4572023_6	1379270.AUXF01000002_gene1159	4.418e-09	70.0	COG0810@1|root,COG0810@2|Bacteria,1ZV4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DYD2_k127_4572023_0	1125863.JAFN01000001_gene2068	2.865e-229	750.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
DYD2_k127_4572023_8	1157708.KB907469_gene59	0.0003055	52.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,4AC9S@80864|Comamonadaceae	28216|Betaproteobacteria	D	PFAM Sporulation domain protein	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
DYD2_k127_4572023_5	861299.J421_0905	5.317e-19	99.0	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
DYD2_k127_4572023_7	1121428.DESHY_40085___1	5.327e-05	53.0	COG5662@1|root,COG5662@2|Bacteria,1U216@1239|Firmicutes,25N56@186801|Clostridia,2631J@186807|Peptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
DYD2_k127_4572023_1	861299.J421_0907	1.529e-84	287.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_4572023_2	861299.J421_0908	1.973e-49	186.0	COG0494@1|root,COG0494@2|Bacteria,1ZTQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
DYD2_k127_4572023_3	861299.J421_0927	3.955e-40	156.0	COG0612@1|root,COG0612@2|Bacteria,1ZT6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DYD2_k127_4573051_0	1123073.KB899242_gene1159	4.094e-32	144.0	COG3209@1|root,COG3386@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,1SZ73@1236|Gammaproteobacteria	1224|Proteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
DYD2_k127_4573051_1	1128421.JAGA01000003_gene2948	1.072e-12	79.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
DYD2_k127_4573090_0	861299.J421_3081	2.968e-59	222.0	COG0739@1|root,COG0739@2|Bacteria,1ZSUW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DYD2_k127_4584676_0	378806.STAUR_6742	2.39e-49	193.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
DYD2_k127_4584676_1	198467.NP92_11085	1.566e-24	106.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,21VRQ@150247|Anoxybacillus	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hbs	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DYD2_k127_4585615_4	1265313.HRUBRA_01348	9.926e-31	126.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
DYD2_k127_4585615_2	1231190.NA8A_16171	8.074e-70	250.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TRFW@28211|Alphaproteobacteria,43I3E@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	with different specificities (related to short-chain alcohol	ygfF	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DYD2_k127_4585615_3	1231190.NA8A_16166	1.831e-68	242.0	COG1028@1|root,COG1028@2|Bacteria	1231190.NA8A_16166|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4585615_1	518766.Rmar_0394	8.912e-119	400.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1FIW1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Na+ dependent nucleoside transporter C-terminus	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
DYD2_k127_4585615_0	1121405.dsmv_1129	5.819e-199	649.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria,2MIC0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
DYD2_k127_4597350_1	768706.Desor_4024	5.568e-05	52.0	COG0860@1|root,COG2247@1|root,COG3103@1|root,COG0860@2|Bacteria,COG2247@2|Bacteria,COG3103@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,260BF@186807|Peptococcaceae	186801|Clostridia	M	Cell Wall	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Big_4,Big_5,CW_binding_2,SH3_3,SPOR
DYD2_k127_4597350_0	379066.GAU_2459	8.642e-06	57.0	2F8UF@1|root,3416F@2|Bacteria,1ZTX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4597350_2	574087.Acear_2298	0.0004427	51.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,3WBRD@53433|Halanaerobiales	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
DYD2_k127_4602051_1	379066.GAU_2498	3.825e-130	434.0	COG2204@1|root,COG2204@2|Bacteria,1ZSWY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
DYD2_k127_4602051_5	861299.J421_3859	1.538e-23	117.0	2F4EZ@1|root,33X55@2|Bacteria,1ZTSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4602051_3	1232410.KI421428_gene972	6.027e-41	158.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2WMK3@28221|Deltaproteobacteria,43SG6@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Ferrous iron transport protein B	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
DYD2_k127_4602051_0	760568.Desku_0398	9.969e-180	572.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,260QM@186807|Peptococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
DYD2_k127_4602051_2	1198452.Jab_2c05880	6.337e-81	274.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,4723Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
DYD2_k127_4602051_4	1379270.AUXF01000003_gene3517	2.583e-26	116.0	COG0544@1|root,COG0544@2|Bacteria,1ZSSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
DYD2_k127_4622090_1	452637.Oter_3821	3.043e-21	98.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
DYD2_k127_4622090_0	861299.J421_3107	1.621e-192	617.0	COG1884@1|root,COG1884@2|Bacteria,1ZT5I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
DYD2_k127_4622090_2	394221.Mmar10_1748	9.201e-16	78.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,43X4F@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	carboxylase	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
DYD2_k127_4628884_0	1280950.HJO_13121	1.428e-58	227.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_16,TPR_8,Trans_reg_C
DYD2_k127_4628884_1	1034943.BN1094_00038	7.78e-45	188.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1JC52@118969|Legionellales	118969|Legionellales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DYD2_k127_4630835_14	1123023.JIAI01000013_gene4025	8.968e-05	55.0	COG0747@1|root,COG0747@2|Bacteria,2IJYA@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DYD2_k127_4630835_3	68194.JNXR01000015_gene7805	7.682e-83	289.0	COG4447@1|root,COG4447@2|Bacteria,2GMJN@201174|Actinobacteria	201174|Actinobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
DYD2_k127_4630835_9	266834.SMc01562	3.857e-26	111.0	COG4274@1|root,COG4274@2|Bacteria,1N29P@1224|Proteobacteria,2UD2U@28211|Alphaproteobacteria,4BKYH@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
DYD2_k127_4630835_12	1293048.CBMB010000004_gene2376	6.966e-07	62.0	COG1208@1|root,arCOG00664@2157|Archaea,2XUW3@28890|Euryarchaeota,23UE8@183963|Halobacteria	183963|Halobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DYD2_k127_4630835_6	861299.J421_0662	1.269e-57	203.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
DYD2_k127_4630835_2	240292.Ava_1652	1.242e-89	301.0	COG4122@1|root,COG4122@2|Bacteria,1G2Y6@1117|Cyanobacteria,1HK98@1161|Nostocales	1117|Cyanobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
DYD2_k127_4630835_0	1121377.KB906402_gene3232	9.354e-136	468.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
DYD2_k127_4630835_5	243365.CV_2753	1.006e-65	250.0	COG2373@1|root,COG4232@1|root,COG2373@2|Bacteria,COG4232@2|Bacteria,1QWZ3@1224|Proteobacteria	1224|Proteobacteria	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
DYD2_k127_4630835_11	616991.JPOO01000003_gene983	7.406e-09	66.0	28HRC@1|root,2Z7YT@2|Bacteria,4NKDD@976|Bacteroidetes,1HYNI@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4630835_15	234267.Acid_2432	0.0001744	55.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
DYD2_k127_4630835_1	388413.ALPR1_00675	2.273e-124	426.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase
DYD2_k127_4630835_10	443144.GM21_3037	4.925e-09	68.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2WVVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
DYD2_k127_4630835_4	1223523.H340_16466	3.569e-81	285.0	COG0059@1|root,COG0059@2|Bacteria,2IK1H@201174|Actinobacteria	201174|Actinobacteria	EH	Acetohydroxy acid isomeroreductase, NADPH-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	IlvC,IlvN
DYD2_k127_4630835_13	861299.J421_1231	1.817e-06	57.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1231|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DYD2_k127_4630835_8	861299.J421_1231	5.597e-33	146.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1231|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DYD2_k127_4630835_7	591167.Sfla_4040	3.085e-37	153.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
DYD2_k127_4638521_3	404589.Anae109_2088	1.769e-78	276.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2YU35@29|Myxococcales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
DYD2_k127_4638521_5	477974.Daud_0042	2.866e-63	239.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,260P1@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
DYD2_k127_4638521_4	1232410.KI421418_gene2299	1.107e-68	255.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DYD2_k127_4638521_1	1379270.AUXF01000005_gene826	4.663e-134	447.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
DYD2_k127_4638521_0	234267.Acid_3470	6.289e-160	534.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
DYD2_k127_4638521_6	861299.J421_3685	8.006e-62	219.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
DYD2_k127_4638521_2	765952.PUV_00830	6.272e-121	400.0	COG0861@1|root,COG0861@2|Bacteria,2JGY6@204428|Chlamydiae	204428|Chlamydiae	P	Integral membrane protein TerC family	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
DYD2_k127_4638521_7	1238182.C882_2419	2.689e-60	219.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2JR2A@204441|Rhodospirillales	204441|Rhodospirillales	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
DYD2_k127_4646610_0	861299.J421_1867	1.301e-240	755.0	COG1429@1|root,COG1429@2|Bacteria	2|Bacteria	H	ligase activity, forming nitrogen-metal bonds	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,Glyco_hydro_63
DYD2_k127_4646610_1	563192.HMPREF0179_03201	1.199e-133	444.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
DYD2_k127_4646610_2	525146.Ddes_0470	8.957e-90	312.0	COG0297@1|root,COG0297@2|Bacteria,1R6U0@1224|Proteobacteria,42Q1W@68525|delta/epsilon subdivisions,2WJXW@28221|Deltaproteobacteria,2M8ZZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
DYD2_k127_4650047_2	861299.J421_2892	8.624e-87	308.0	COG1104@1|root,COG1104@2|Bacteria,1ZSXD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
DYD2_k127_4650047_5	379066.GAU_1135	2.494e-80	288.0	COG2120@1|root,COG2120@2|Bacteria,1ZTDK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
DYD2_k127_4650047_3	379066.GAU_1144	1.076e-84	311.0	COG0577@1|root,COG0577@2|Bacteria,1ZUN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DYD2_k127_4650047_4	379066.GAU_1143	4.244e-84	304.0	COG0577@1|root,COG0577@2|Bacteria,1ZSU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
DYD2_k127_4650047_1	1379270.AUXF01000005_gene457	9.959e-101	343.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD2_k127_4650047_0	861299.J421_2903	4.306e-103	352.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
DYD2_k127_4658992_0	926566.Terro_0850	6.892e-134	441.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DYD2_k127_4658992_1	457415.HMPREF1006_01725	2.106e-36	156.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
DYD2_k127_4673591_3	379066.GAU_0464	1.652e-17	93.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4673591_0	316274.Haur_1203	3.319e-109	365.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DYD2_k127_4673591_2	675815.VOA_002278	3.785e-30	133.0	COG0824@1|root,COG0824@2|Bacteria,1RHCN@1224|Proteobacteria,1S4PS@1236|Gammaproteobacteria,1XXBU@135623|Vibrionales	135623|Vibrionales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
DYD2_k127_4673591_4	1125863.JAFN01000001_gene3142	9.725e-16	88.0	COG0671@1|root,COG0671@2|Bacteria,1QUKE@1224|Proteobacteria,42XAW@68525|delta/epsilon subdivisions,2WSJV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
DYD2_k127_4673591_1	861299.J421_2731	3.595e-43	168.0	COG1195@1|root,COG1195@2|Bacteria,1ZSRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
DYD2_k127_4688185_1	760568.Desku_0659	1.79e-113	404.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,2601M@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
DYD2_k127_4688185_0	379066.GAU_0644	7.973e-159	544.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DYD2_k127_4689831_4	105425.BBPL01000037_gene4244	1.177e-21	107.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria,2NFSN@228398|Streptacidiphilus	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6
DYD2_k127_4689831_1	1356852.N008_07470	2.214e-199	646.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
DYD2_k127_4689831_2	671143.DAMO_3114	4.418e-74	256.0	COG0602@1|root,COG0602@2|Bacteria,2NPEM@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100	-	R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
DYD2_k127_4689831_3	290397.Adeh_3497	8.415e-41	156.0	COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,4352K@68525|delta/epsilon subdivisions,2WZDN@28221|Deltaproteobacteria,2Z1WQ@29|Myxococcales	28221|Deltaproteobacteria	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
DYD2_k127_4689831_0	379066.GAU_2903	4.139e-223	709.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DYD2_k127_4753952_0	1123253.AUBD01000005_gene136	2.057e-125	434.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1X3AE@135614|Xanthomonadales	135614|Xanthomonadales	F	Na dependent nucleoside transporter	yeiM	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
DYD2_k127_4753952_2	404589.Anae109_1579	6.949e-78	267.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DYD2_k127_4753952_1	706587.Desti_1689	1.658e-80	295.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MR7D@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DYD2_k127_4760567_0	379066.GAU_2477	5.215e-128	418.0	COG0473@1|root,COG0473@2|Bacteria,1ZTDX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
DYD2_k127_4760567_1	1192034.CAP_0301	1.586e-31	140.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,43B0B@68525|delta/epsilon subdivisions,2X6EF@28221|Deltaproteobacteria,2Z3AR@29|Myxococcales	28221|Deltaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
DYD2_k127_4805056_1	1380390.JIAT01000010_gene4328	1.181e-82	285.0	COG2218@1|root,COG2218@2|Bacteria	2|Bacteria	C	formylmethanofuran dehydrogenase activity	fhcC	GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281	1.2.7.12	ko:K00202	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	GXGXG
DYD2_k127_4805056_0	1380390.JIAT01000010_gene4326	2.598e-164	529.0	COG1229@1|root,COG1229@2|Bacteria	2|Bacteria	C	Formylmethanofuran dehydrogenase subunit A	fhcA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
DYD2_k127_4806946_2	867903.ThesuDRAFT_01723	5.191e-16	93.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,258QY@186801|Clostridia,3WDPB@538999|Clostridiales incertae sedis	186801|Clostridia	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
DYD2_k127_4806946_1	861299.J421_2808	2.13e-96	353.0	COG0492@1|root,COG0492@2|Bacteria,1ZSW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
DYD2_k127_4806946_0	251221.35212555	5.156e-107	376.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria	1117|Cyanobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
DYD2_k127_4812194_8	1457250.BBMO01000001_gene1903	1.411e-35	142.0	COG1522@1|root,arCOG01580@2157|Archaea,2XWJA@28890|Euryarchaeota,23V54@183963|Halobacteria	183963|Halobacteria	K	COG1522 Transcriptional regulators	asnC1	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
DYD2_k127_4812194_3	266117.Rxyl_2949	6.681e-86	300.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
DYD2_k127_4812194_7	266117.Rxyl_0321	7.265e-41	166.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
DYD2_k127_4812194_5	290397.Adeh_1286	1.068e-62	222.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD2_k127_4812194_0	880072.Desac_2405	1.219e-194	632.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,2MQ66@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
DYD2_k127_4812194_4	765912.Thimo_1388	1.685e-73	280.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,1TK7U@1236|Gammaproteobacteria,1X089@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8
DYD2_k127_4812194_2	1232410.KI421426_gene1373	9.183e-93	313.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,43U78@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
DYD2_k127_4812194_1	861299.J421_2400	1.859e-121	411.0	COG1748@1|root,COG1748@2|Bacteria,1ZSMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
DYD2_k127_4812194_10	204669.Acid345_2199	1.735e-14	85.0	COG1725@1|root,COG1725@2|Bacteria,3Y8PU@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07978	-	-	-	-	ko00000,ko03000	-	-	-	GntR
DYD2_k127_4812194_6	1040983.AXAE01000035_gene2354	1.769e-53	209.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43JWG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_2
DYD2_k127_4812194_9	1265313.HRUBRA_01348	4.017e-17	85.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
DYD2_k127_4828281_5	530564.Psta_3253	5.589e-89	314.0	COG0515@1|root,COG0515@2|Bacteria,2J50A@203682|Planctomycetes	530564.Psta_3253|-	KLT	PFAM Serine threonine protein kinase-related	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4828281_8	1125863.JAFN01000001_gene3018	1.182e-43	182.0	COG4191@1|root,COG4191@2|Bacteria,1R95R@1224|Proteobacteria,42PEG@68525|delta/epsilon subdivisions,2WM8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
DYD2_k127_4828281_2	502025.Hoch_3302	1.161e-121	409.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WMKF@28221|Deltaproteobacteria,2YWSM@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DYD2_k127_4828281_9	1379698.RBG1_1C00001G0501	4.735e-30	132.0	COG2885@1|root,COG2885@2|Bacteria,2NPMV@2323|unclassified Bacteria	2|Bacteria	M	OmpA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
DYD2_k127_4828281_10	518766.Rmar_2767	1.894e-28	126.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	coxG	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
DYD2_k127_4828281_6	330214.NIDE4307	2.942e-64	240.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	Z012_00180	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
DYD2_k127_4828281_4	518766.Rmar_2377	4.06e-97	325.0	COG0714@1|root,COG0714@2|Bacteria,4NIE6@976|Bacteroidetes	976|Bacteroidetes	S	PFAM ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
DYD2_k127_4828281_7	1122223.KB890701_gene2229	2.322e-58	226.0	COG3552@1|root,COG3552@2|Bacteria,1WMMT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
DYD2_k127_4828281_3	565045.NOR51B_2777	7.024e-120	400.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1T3SF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
DYD2_k127_4828281_1	867903.ThesuDRAFT_01061	3.72e-127	438.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
DYD2_k127_4828281_0	861299.J421_1029	1.652e-138	453.0	COG3191@1|root,COG3191@2|Bacteria,1ZT47@142182|Gemmatimonadetes	2|Bacteria	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
DYD2_k127_4833870_3	1379270.AUXF01000006_gene54	1.251e-55	203.0	COG2870@1|root,COG2870@2|Bacteria,1ZT0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
DYD2_k127_4833870_1	861299.J421_3477	9.604e-80	274.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DYD2_k127_4833870_0	861299.J421_3476	2.905e-87	300.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	2|Bacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DYD2_k127_4833870_2	861299.J421_3475	3.878e-59	217.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	ttg2C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DYD2_k127_4833870_5	1123057.P872_19625	1.909e-05	53.0	2DBIE@1|root,32ZYG@2|Bacteria,4NX43@976|Bacteroidetes,47SEP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_4833870_4	861299.J421_0057	2.564e-39	152.0	COG0782@1|root,COG0782@2|Bacteria,1ZTPD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
DYD2_k127_4867274_1	861299.J421_3894	1.644e-121	405.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
DYD2_k127_4867274_0	1121957.ATVL01000011_gene3611	9.286e-214	681.0	COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,47KVG@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
DYD2_k127_4867274_2	877455.Metbo_1641	3.402e-20	96.0	COG3339@1|root,arCOG06459@2157|Archaea,2Y1VZ@28890|Euryarchaeota,23PPP@183925|Methanobacteria	183925|Methanobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
DYD2_k127_4898087_3	765914.ThisiDRAFT_1162	3.842e-37	149.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,1X29U@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
DYD2_k127_4898087_4	379066.GAU_1713	5.079e-24	109.0	COG0319@1|root,COG0319@2|Bacteria,1ZTUP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
DYD2_k127_4898087_1	861299.J421_3354	1.536e-124	431.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
DYD2_k127_4898087_2	861299.J421_3355	7.022e-116	383.0	COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
DYD2_k127_4898087_0	477974.Daud_0906	2.192e-137	452.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
DYD2_k127_4925984_1	861299.J421_4180	2.471e-06	56.0	COG1836@1|root,COG1836@2|Bacteria,1ZTT3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
DYD2_k127_4925984_0	1121091.AUMP01000002_gene2133	9.457e-79	285.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4IS7E@91061|Bacilli	91061|Bacilli	E	methionine gamma-lyase	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
DYD2_k127_492890_2	1123508.JH636441_gene3711	1.964e-39	151.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,Response_reg
DYD2_k127_492890_3	469383.Cwoe_4930	0.0001347	55.0	COG2199@1|root,COG5278@1|root,COG3706@2|Bacteria,COG5278@2|Bacteria,2IA4H@201174|Actinobacteria,4CP5Q@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
DYD2_k127_492890_0	861299.J421_3930	2.728e-84	297.0	COG2025@1|root,COG2025@2|Bacteria,1ZTDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
DYD2_k127_492890_1	880073.Calab_1575	1.602e-71	255.0	COG2086@1|root,COG2086@2|Bacteria,2NP4J@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
DYD2_k127_4980402_0	861299.J421_4070	1.594e-226	724.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
DYD2_k127_4994820_2	1869.MB27_36650	4.285e-14	79.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2GZ7K@201174|Actinobacteria,4DF55@85008|Micromonosporales	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
DYD2_k127_4994820_0	1232410.KI421413_gene849	2.997e-149	488.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD2_k127_4994820_1	469383.Cwoe_5609	4.988e-68	242.0	COG0558@1|root,COG0558@2|Bacteria,2H9R3@201174|Actinobacteria	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
DYD2_k127_5002015_2	1219045.BV98_000361	4.197e-21	100.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_5002015_1	1131814.JAFO01000001_gene4096	8.332e-26	115.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,3F1EC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_5002015_0	378806.STAUR_2943	9.632e-59	229.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria,2YYUS@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
DYD2_k127_5014572_2	1173026.Glo7428_2730	1.103e-63	228.0	COG2602@1|root,COG2602@2|Bacteria,1FZZV@1117|Cyanobacteria	1117|Cyanobacteria	V	PFAM Penicillin binding protein transpeptidase domain	-	-	3.5.2.6	ko:K17838	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Transpeptidase
DYD2_k127_5014572_0	861299.J421_4121	4.069e-273	859.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
DYD2_k127_5014572_1	1121104.AQXH01000001_gene1705	5.634e-65	234.0	COG3544@1|root,COG3544@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
DYD2_k127_5020650_3	1121127.JAFA01000006_gene5461	9.582e-07	61.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VT4G@28216|Betaproteobacteria,1K4A3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DYD2_k127_5020650_1	1944.JOAZ01000014_gene4375	1.187e-64	235.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,41988@629295|Streptomyces griseus group	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
DYD2_k127_5020650_2	861299.J421_2159	1.138e-63	243.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	coxS	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
DYD2_k127_5020650_0	867903.ThesuDRAFT_02019	1.018e-111	381.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
DYD2_k127_5020976_6	886293.Sinac_3002	1.13e-28	132.0	29VFX@1|root,30GX8@2|Bacteria,2IZ6B@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
DYD2_k127_5020976_3	880073.Calab_2884	5.873e-84	292.0	COG0345@1|root,COG0345@2|Bacteria,2NPIR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899,iIT341.HP1158,iSBO_1134.SBO_0282,ic_1306.c0493	F420_oxidored,P5CR_dimer
DYD2_k127_5020976_5	545694.TREPR_0455	1.344e-34	142.0	COG0705@1|root,COG0705@2|Bacteria,2J7HV@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
DYD2_k127_5020976_1	519442.Huta_2316	1.366e-111	379.0	COG0276@1|root,arCOG05373@2157|Archaea,2XTYB@28890|Euryarchaeota,23TSA@183963|Halobacteria	183963|Halobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
DYD2_k127_5020976_2	1137269.AZWL01000022_gene3485	9.213e-95	329.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
DYD2_k127_5020976_7	378806.STAUR_8052	8.594e-16	88.0	2EV1C@1|root,33NGG@2|Bacteria,1NKKY@1224|Proteobacteria,42X6Y@68525|delta/epsilon subdivisions,2WTH7@28221|Deltaproteobacteria,2Z0VE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5020976_0	1242864.D187_007813	1.425e-136	464.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
DYD2_k127_5020976_4	518766.Rmar_2068	4.148e-36	152.0	COG3391@1|root,COG3391@2|Bacteria,4NXXN@976|Bacteroidetes	976|Bacteroidetes	S	TolB-like 6-blade propeller-like	-	-	-	-	-	-	-	-	-	-	-	-	TolB_like
DYD2_k127_5022934_4	861299.J421_1545	6.57e-74	274.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	BTAD
DYD2_k127_5022934_2	861299.J421_1863	9.44e-135	465.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
DYD2_k127_5022934_1	195253.Syn6312_2199	1.75e-187	602.0	COG0422@1|root,COG0422@2|Bacteria,1G2N9@1117|Cyanobacteria,1GYR0@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
DYD2_k127_5022934_0	1089552.KI911559_gene3543	5.061e-301	943.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPZI@204441|Rhodospirillales	204441|Rhodospirillales	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
DYD2_k127_5022934_3	404589.Anae109_3310	1.112e-91	317.0	COG0546@1|root,COG0546@2|Bacteria,1RCPM@1224|Proteobacteria,42SYW@68525|delta/epsilon subdivisions,2WP6C@28221|Deltaproteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
DYD2_k127_5022934_5	861299.J421_3991	3.421e-36	146.0	29F5I@1|root,30238@2|Bacteria,1ZU4C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5045392_0	518766.Rmar_0629	7.823e-145	484.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
DYD2_k127_5045392_12	1038869.AXAN01000021_gene2034	1.996e-25	111.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,1K7QN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
DYD2_k127_5045392_4	32057.KB217478_gene6746	5.469e-65	237.0	COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,1HRYE@1161|Nostocales	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5045392_9	671143.DAMO_0398	2.074e-40	168.0	COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	iscA	-	-	ko:K07400,ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn,Nfu_N,NifU
DYD2_k127_5045392_3	246197.MXAN_7405	4.521e-75	259.0	COG0506@1|root,COG0506@2|Bacteria,1R8VR@1224|Proteobacteria,42P21@68525|delta/epsilon subdivisions,2WJU2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DYD2_k127_5045392_8	1379270.AUXF01000002_gene1195	1.288e-49	183.0	COG0461@1|root,COG0461@2|Bacteria,1ZTMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
DYD2_k127_5045392_10	1379270.AUXF01000004_gene2965	2.496e-36	145.0	COG0735@1|root,COG0735@2|Bacteria,1ZTN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DYD2_k127_5045392_6	861299.J421_2675	7.328e-54	199.0	2ED0A@1|root,336X9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5045392_13	1123389.ATXJ01000016_gene53	2.281e-13	81.0	COG1371@1|root,COG1371@2|Bacteria,1WJYM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
DYD2_k127_5045392_11	765914.ThisiDRAFT_0880	9.861e-36	146.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1S7AR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	exported protein	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
DYD2_k127_5045392_5	867903.ThesuDRAFT_01213	3.387e-57	205.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,25F3I@186801|Clostridia,3WCCI@538999|Clostridiales incertae sedis	186801|Clostridia	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
DYD2_k127_5045392_1	867903.ThesuDRAFT_01213	5.722e-128	416.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,25F3I@186801|Clostridia,3WCCI@538999|Clostridiales incertae sedis	186801|Clostridia	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
DYD2_k127_5045392_14	287.DR97_4208	0.0003324	53.0	2DM5E@1|root,31SVN@2|Bacteria,1MYKR@1224|Proteobacteria,1SF2N@1236|Gammaproteobacteria,1YESB@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
DYD2_k127_5045392_7	1177179.A11A3_07023	2.929e-53	214.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1XNME@135619|Oceanospirillales	135619|Oceanospirillales	N	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
DYD2_k127_5045392_2	1227739.Hsw_2741	1.278e-82	285.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47KF6@768503|Cytophagia	976|Bacteroidetes	V	TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD2_k127_5046074_0	861299.J421_3472	2.4e-114	380.0	COG0536@1|root,COG0536@2|Bacteria,1ZSVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
DYD2_k127_5046074_1	861299.J421_3473	3.38e-35	143.0	COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
DYD2_k127_50560_1	861299.J421_1148	5.261e-43	168.0	2DTII@1|root,33KI8@2|Bacteria,1ZT3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_50560_0	861299.J421_1151	1.404e-114	385.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
DYD2_k127_5078122_3	379066.GAU_2382	2.223e-124	404.0	COG1013@1|root,COG1013@2|Bacteria,1ZSWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
DYD2_k127_5078122_1	861299.J421_1490	1.235e-251	819.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1ZSVF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
DYD2_k127_5078122_0	861299.J421_1491	1.965e-273	875.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1ZSZ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
DYD2_k127_5078122_4	1210884.HG799466_gene12816	4.343e-69	253.0	COG2203@1|root,COG3852@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
DYD2_k127_5078122_2	351607.Acel_1492	1.607e-148	479.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4ERDP@85013|Frankiales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
DYD2_k127_5078122_7	292459.STH1666	7.369e-11	71.0	COG2137@1|root,COG2137@2|Bacteria	2|Bacteria	S	regulation of DNA repair	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
DYD2_k127_5078122_6	1379281.AVAG01000033_gene424	9.753e-47	172.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2M7ZN@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
DYD2_k127_507911_1	379066.GAU_2526	5.062e-91	324.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
DYD2_k127_507911_0	1379270.AUXF01000003_gene3386	1.053e-172	554.0	COG2204@1|root,COG2204@2|Bacteria,1ZSRQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DYD2_k127_507911_2	56780.SYN_00814	3.96e-15	81.0	COG4969@1|root,COG4969@2|Bacteria,1QV9X@1224|Proteobacteria,42W4E@68525|delta/epsilon subdivisions,2X70G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
DYD2_k127_5103769_0	517418.Ctha_1907	6.358e-263	842.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	pqqL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DYD2_k127_5103769_3	1283300.ATXB01000001_gene2112	2.736e-43	161.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1T12G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5103769_5	379066.GAU_2220	1.341e-23	116.0	2EQTX@1|root,33IDK@2|Bacteria,1ZUY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5103769_1	251221.35213651	9.988e-71	257.0	COG3217@1|root,COG3217@2|Bacteria,1G41J@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
DYD2_k127_5103769_2	981384.AEYW01000006_gene2258	1.653e-70	260.0	COG2128@1|root,COG2128@2|Bacteria,1PQ1G@1224|Proteobacteria,2U17A@28211|Alphaproteobacteria,4NBJF@97050|Ruegeria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
DYD2_k127_5103769_6	525904.Tter_0756	9.916e-20	96.0	COG1595@1|root,COG1595@2|Bacteria,2NPHU@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_5103769_4	323848.Nmul_A0328	2.177e-36	153.0	COG2199@1|root,COG2200@1|root,COG3829@1|root,COG3852@1|root,COG5002@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WHDZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
DYD2_k127_5105376_1	1379270.AUXF01000006_gene80	4.541e-46	178.0	COG0847@1|root,COG0847@2|Bacteria,1ZTNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
DYD2_k127_5105376_0	742817.HMPREF9449_01289	8.685e-77	272.0	COG2235@1|root,COG2235@2|Bacteria	2|Bacteria	E	arginine	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
DYD2_k127_5112030_6	880073.Calab_2331	5.029e-11	76.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_2331|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5112030_2	926690.KE386573_gene1776	1.984e-79	287.0	arCOG04118@1|root,arCOG04118@2157|Archaea,2XW4Q@28890|Euryarchaeota,23T6U@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5112030_0	1191523.MROS_1826	1.879e-125	416.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_14,LAM_C,Radical_SAM
DYD2_k127_5112030_3	1121861.KB899916_gene1705	1.181e-69	257.0	COG0454@1|root,COG1181@1|root,COG0456@2|Bacteria,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,2U1M9@28211|Alphaproteobacteria,2JYEI@204441|Rhodospirillales	204441|Rhodospirillales	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C
DYD2_k127_5112030_1	1232410.KI421421_gene3684	2.96e-89	306.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,43UHD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
DYD2_k127_5112030_7	1294265.JCM21738_1068	5.356e-11	66.0	2BFS6@1|root,329M0@2|Bacteria,1UBZZ@1239|Firmicutes,4INFW@91061|Bacilli,1ZNF2@1386|Bacillus	91061|Bacilli	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
DYD2_k127_5112030_4	867903.ThesuDRAFT_00462	3.182e-67	246.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3WCDZ@538999|Clostridiales incertae sedis	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
DYD2_k127_5114434_4	861299.J421_2683	2.691e-56	216.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DYD2_k127_5114434_8	309807.SRU_1452	6.603e-33	139.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5114434_7	861299.J421_0830	3.209e-35	157.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_0830|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5114434_1	861299.J421_0829	1.38e-112	387.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GAF,HTH_8,Sigma54_activat
DYD2_k127_5114434_2	525904.Tter_0658	1.763e-78	274.0	COG0040@1|root,COG0040@2|Bacteria,2NPA9@2323|unclassified Bacteria	2|Bacteria	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_1909	HisG,HisG_C
DYD2_k127_5114434_0	379066.GAU_0139	3.2e-125	447.0	COG0079@1|root,COG0141@1|root,COG0079@2|Bacteria,COG0141@2|Bacteria,1ZT8V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
DYD2_k127_5114434_3	1118235.CAJH01000010_gene601	1.547e-57	231.0	COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1X38F@135614|Xanthomonadales	135614|Xanthomonadales	E	Histidine biosynthesis bifunctional protein HisB	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_like,IGPD,PNK3P
DYD2_k127_5114434_6	925775.XVE_4640	1.473e-43	177.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1X5IB@135614|Xanthomonadales	135614|Xanthomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
DYD2_k127_5114434_5	867903.ThesuDRAFT_01964	1.974e-48	190.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,3WDDN@538999|Clostridiales incertae sedis	186801|Clostridia	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
DYD2_k127_5122090_0	1191523.MROS_2246	3.808e-119	397.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
DYD2_k127_513675_2	489825.LYNGBM3L_38110	4.119e-38	148.0	COG1216@1|root,COG1216@2|Bacteria,1GQEZ@1117|Cyanobacteria,1HI6Y@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2,Methyltransf_23
DYD2_k127_513675_0	489825.LYNGBM3L_38110	2.185e-72	270.0	COG1216@1|root,COG1216@2|Bacteria,1GQEZ@1117|Cyanobacteria,1HI6Y@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2,Methyltransf_23
DYD2_k127_513675_1	1335760.ASTG01000016_gene80	4.471e-47	187.0	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,2TTZ8@28211|Alphaproteobacteria,2K38D@204457|Sphingomonadales	204457|Sphingomonadales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
DYD2_k127_5154415_3	861299.J421_1060	1.225e-92	309.0	COG0035@1|root,COG0035@2|Bacteria,1ZT1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
DYD2_k127_5154415_1	1121448.DGI_2568	8.359e-109	370.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2M8CP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DYD2_k127_5154415_2	518766.Rmar_0734	1.323e-97	334.0	COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,1FJEY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
DYD2_k127_5154415_4	518766.Rmar_0139	3.23e-58	209.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1FJ8V@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
DYD2_k127_5154415_0	518766.Rmar_0138	5.63e-130	429.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1FIT8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
DYD2_k127_5156995_2	570967.JMLV01000001_gene2644	3.244e-20	94.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,2JRPM@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
DYD2_k127_5156995_0	391596.PBAL39_02197	6.575e-110	371.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia	976|Bacteroidetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
DYD2_k127_5156995_1	926560.KE387027_gene345	3.58e-50	201.0	COG3291@1|root,COG3291@2|Bacteria,1WKMB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	N	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M8
DYD2_k127_515995_4	765910.MARPU_11855	1.354e-18	101.0	COG0526@1|root,COG0526@2|Bacteria,1RJUZ@1224|Proteobacteria,1S6Y0@1236|Gammaproteobacteria,1WYNQ@135613|Chromatiales	135613|Chromatiales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
DYD2_k127_515995_0	324602.Caur_0549	8.795e-110	375.0	COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
DYD2_k127_515995_2	247490.KSU1_D1054	4.016e-39	153.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,F5_F8_type_C
DYD2_k127_515995_7	666685.R2APBS1_3798	4.053e-13	75.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,1RZGS@1236|Gammaproteobacteria,1XBRV@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
DYD2_k127_515995_3	243230.DR_1765	2.228e-19	90.0	COG2128@1|root,COG2128@2|Bacteria,1WJIC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
DYD2_k127_515995_1	518766.Rmar_2711	2.188e-98	337.0	COG2252@1|root,COG2252@2|Bacteria,4NGCG@976|Bacteroidetes	976|Bacteroidetes	S	Permease	yieG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
DYD2_k127_515995_5	1192034.CAP_1403	6.527e-14	74.0	COG3209@1|root,COG3292@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3292@2|Bacteria,COG3391@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2YUH1@29|Myxococcales	28221|Deltaproteobacteria	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
DYD2_k127_5167305_0	861299.J421_3101	8.846e-132	434.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
DYD2_k127_5184702_2	861299.J421_1231	1.947e-43	183.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1231|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DYD2_k127_5184702_0	379066.GAU_2797	7.139e-309	967.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DYD2_k127_5184702_1	42256.RradSPS_2430	1.992e-85	293.0	COG3361@1|root,COG3361@2|Bacteria,2I6N0@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
DYD2_k127_5199326_7	293826.Amet_2771	9.509e-25	109.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,36E63@31979|Clostridiaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
DYD2_k127_5199326_6	861299.J421_2950	1.397e-33	145.0	COG0359@1|root,COG0359@2|Bacteria,1ZTNG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
DYD2_k127_5199326_10	861299.J421_2951	9.757e-18	94.0	2F1RZ@1|root,33US3@2|Bacteria,1ZUSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
DYD2_k127_5199326_9	580340.Tlie_1323	2.532e-19	91.0	COG0238@1|root,COG0238@2|Bacteria,3TBFC@508458|Synergistetes	508458|Synergistetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
DYD2_k127_5199326_8	1379270.AUXF01000005_gene514	4.009e-21	98.0	COG0360@1|root,COG0360@2|Bacteria,1ZTYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
DYD2_k127_5199326_0	56780.SYN_02772	8.89e-228	733.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,2MQUH@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
DYD2_k127_5199326_4	1379270.AUXF01000005_gene524	5.086e-45	171.0	COG0193@1|root,COG0193@2|Bacteria,1ZTKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
DYD2_k127_5199326_5	1379270.AUXF01000005_gene525	1.384e-39	156.0	COG1825@1|root,COG1825@2|Bacteria,1ZTHZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
DYD2_k127_5199326_1	379066.GAU_1219	2.139e-129	421.0	COG0462@1|root,COG0462@2|Bacteria,1ZT7Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
DYD2_k127_5199326_2	518766.Rmar_0905	2.552e-101	360.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
DYD2_k127_5199326_3	266117.Rxyl_1210	1.994e-81	286.0	COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
DYD2_k127_5216765_2	861299.J421_3748	4.782e-10	72.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	BatA,CARDB,F5_F8_type_C,HemolysinCabind,Laminin_G_3,NIDO,VWA_2
DYD2_k127_5216765_0	1379270.AUXF01000003_gene3696	5.616e-77	282.0	COG1721@1|root,COG1721@2|Bacteria,1ZT0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DYD2_k127_5216765_1	1121930.AQXG01000005_gene724	5.921e-60	230.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
DYD2_k127_5236732_2	765420.OSCT_3012	7.818e-31	136.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi,375B8@32061|Chloroflexia	32061|Chloroflexia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
DYD2_k127_5236732_1	698758.AXY_08130	4.954e-41	158.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli	91061|Bacilli	C	SUF system FeS assembly protein, NifU family	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DYD2_k127_5236732_0	266117.Rxyl_0166	3.951e-150	485.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CPE2@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
DYD2_k127_5236732_3	1033730.CAHG01000014_gene1626	3.374e-16	79.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4DRMD@85009|Propionibacteriales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	sufE	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
DYD2_k127_523690_1	1499967.BAYZ01000094_gene4048	3.96e-25	117.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
DYD2_k127_523690_0	1125863.JAFN01000001_gene3501	2.257e-47	184.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2WP2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DYD2_k127_523696_1	1237149.C900_04897	5.69e-43	176.0	COG1672@1|root,COG1672@2|Bacteria,4NN64@976|Bacteroidetes,47UYI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_523696_0	518766.Rmar_0141	1.305e-65	235.0	COG0668@1|root,COG0668@2|Bacteria,4NMNE@976|Bacteroidetes	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
DYD2_k127_5244549_1	765420.OSCT_0142	0.0001422	45.0	COG0546@1|root,COG0546@2|Bacteria,2G9CI@200795|Chloroflexi,375VN@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
DYD2_k127_5244549_0	1288826.MSNKSG1_10703	8.377e-14	78.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,1SASV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1651 Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
DYD2_k127_5261506_6	1254432.SCE1572_21210	1.212e-36	143.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_5261506_5	234267.Acid_5756	5.939e-60	226.0	COG0515@1|root,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
DYD2_k127_5261506_2	1121468.AUBR01000058_gene875	1.548e-77	274.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,24ETR@186801|Clostridia,42FP9@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DYD2_k127_5261506_4	429009.Adeg_0394	9.255e-66	235.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,42GU1@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
DYD2_k127_5261506_1	1232410.KI421428_gene1030	1.394e-81	280.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
DYD2_k127_5261506_0	1379698.RBG1_1C00001G0607	1.213e-108	372.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
DYD2_k127_5261506_3	684949.ATTJ01000001_gene1661	7.197e-72	249.0	COG0535@1|root,COG0535@2|Bacteria,1WICG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DYD2_k127_5273815_3	98439.AJLL01000102_gene434	1.047e-54	215.0	COG0438@1|root,COG4122@1|root,COG0438@2|Bacteria,COG4122@2|Bacteria,1FZUY@1117|Cyanobacteria,1JK81@1189|Stigonemataceae	1117|Cyanobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_11,Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_21,Methyltransf_24
DYD2_k127_5273815_1	105559.Nwat_0873	4.287e-139	448.0	KOG2165@1|root,2Z911@2|Bacteria,1N8JM@1224|Proteobacteria,1RR9Z@1236|Gammaproteobacteria,1WWIT@135613|Chromatiales	135613|Chromatiales	S	ubiquitin protein ligase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5273815_0	323261.Noc_2221	1.21e-296	943.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1X0IX@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
DYD2_k127_5273815_2	472759.Nhal_3587	5.1e-114	387.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,1SKJ8@1236|Gammaproteobacteria,1X0FH@135613|Chromatiales	135613|Chromatiales	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
DYD2_k127_5273815_4	861299.J421_0777	4.049e-52	199.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
DYD2_k127_5273815_5	1121930.AQXG01000005_gene584	1.161e-18	93.0	2CDZB@1|root,3340J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_52808_4	349124.Hhal_2312	7.835e-43	173.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,1RS25@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
DYD2_k127_52808_6	379066.GAU_0297	1.662e-05	58.0	2BXJW@1|root,2ZMND@2|Bacteria,1ZU82@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_52808_3	861299.J421_0207	1.504e-58	216.0	COG1191@1|root,COG1191@2|Bacteria,1ZSY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
DYD2_k127_52808_1	861299.J421_0175	1.993e-166	537.0	COG2204@1|root,COG2204@2|Bacteria,1ZTDN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DYD2_k127_52808_2	861299.J421_4209	6.446e-60	220.0	COG1131@1|root,COG1131@2|Bacteria,1ZV6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
DYD2_k127_52808_0	861299.J421_2513	5.591e-167	541.0	COG4867@1|root,COG4867@2|Bacteria,1ZT0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
DYD2_k127_52808_5	479434.Sthe_2931	2.379e-35	145.0	COG0253@1|root,COG0253@2|Bacteria,2G99B@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
DYD2_k127_5285329_4	262724.TT_C1257	5.565e-08	55.0	COG0071@1|root,COG0071@2|Bacteria,1WJU3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DYD2_k127_5285329_0	1128421.JAGA01000002_gene1937	1.923e-81	289.0	COG0477@1|root,COG2814@2|Bacteria,2NS3M@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
DYD2_k127_5285329_2	1382306.JNIM01000001_gene1519	4.05e-31	131.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
DYD2_k127_5285329_1	1267533.KB906735_gene4630	9.71e-47	184.0	COG0475@1|root,COG0475@2|Bacteria,3Y9G2@57723|Acidobacteria,2JNWD@204432|Acidobacteriia	204432|Acidobacteriia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
DYD2_k127_5285329_3	1313265.JNIE01000005_gene278	1.799e-23	103.0	COG0490@1|root,COG0490@2|Bacteria,2G45Z@200783|Aquificae	200783|Aquificae	P	TrkA-C domain protein	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
DYD2_k127_5286380_0	379066.GAU_1403	4.307e-82	284.0	COG0564@1|root,COG0564@2|Bacteria,1ZSXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
DYD2_k127_5286380_2	1379270.AUXF01000005_gene663	2.682e-34	142.0	COG0597@1|root,COG0597@2|Bacteria,1ZTWA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
DYD2_k127_5286380_1	861299.J421_3049	1.598e-46	169.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
DYD2_k127_5297500_1	379066.GAU_1468	8.9e-98	342.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
DYD2_k127_5297500_0	1125863.JAFN01000001_gene3284	9.023e-135	448.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
DYD2_k127_5307640_3	1121015.N789_07825	2.089e-35	151.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1X42D@135614|Xanthomonadales	135614|Xanthomonadales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
DYD2_k127_5307640_0	861299.J421_3861	4.104e-96	322.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
DYD2_k127_5307640_1	886293.Sinac_3291	1.32e-37	148.0	COG4636@1|root,COG4636@2|Bacteria,2J0XX@203682|Planctomycetes	203682|Planctomycetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
DYD2_k127_5307640_2	926569.ANT_01880	4.822e-37	156.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
DYD2_k127_5307640_4	370438.PTH_1630	4.942e-23	113.0	COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,24N1H@186801|Clostridia,262D3@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	aroH	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
DYD2_k127_5308181_4	861299.J421_3408	1.914e-82	281.0	COG0020@1|root,COG0020@2|Bacteria,1ZSNJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
DYD2_k127_5308181_11	861299.J421_3407	1.875e-46	180.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
DYD2_k127_5308181_3	861299.J421_3406	2.961e-110	370.0	COG0743@1|root,COG0743@2|Bacteria,1ZTFR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
DYD2_k127_5308181_7	1125863.JAFN01000001_gene963	1.236e-76	270.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
DYD2_k127_5308181_10	861299.J421_3169	1.133e-56	222.0	COG1235@1|root,COG1235@2|Bacteria,1ZTN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
DYD2_k127_5308181_9	861299.J421_3170	5.826e-63	233.0	COG1208@1|root,COG1208@2|Bacteria,1ZSVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
DYD2_k127_5308181_6	1379270.AUXF01000005_gene805	2.361e-77	291.0	COG0836@1|root,COG0836@2|Bacteria,1ZT5Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
DYD2_k127_5308181_2	861299.J421_3175	2.36e-147	476.0	COG0172@1|root,COG0172@2|Bacteria,1ZT0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
DYD2_k127_5308181_8	861299.J421_3176	6.268e-72	259.0	COG5000@1|root,COG5000@2|Bacteria,1ZSKZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
DYD2_k127_5308181_1	1379270.AUXF01000005_gene811	8.443e-180	609.0	COG0210@1|root,COG0210@2|Bacteria,1ZTD5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
DYD2_k127_5308181_0	861299.J421_4478	6.409e-203	647.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
DYD2_k127_5308181_5	861299.J421_3181	3.425e-78	280.0	28Q1P@1|root,2ZB8E@2|Bacteria,1ZSPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
DYD2_k127_5308476_1	1121033.AUCF01000031_gene84	1.752e-30	139.0	COG1721@1|root,COG1721@2|Bacteria,1R69F@1224|Proteobacteria,2U4IS@28211|Alphaproteobacteria,2JWWD@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
DYD2_k127_5308476_0	316056.RPC_1911	8.841e-51	197.0	COG0714@1|root,COG0714@2|Bacteria,1MUCP@1224|Proteobacteria,2U0P9@28211|Alphaproteobacteria,3K2GZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	mxaR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	AAA_3
DYD2_k127_5308476_2	96561.Dole_1757	1.712e-08	57.0	COG2931@1|root,COG2931@2|Bacteria,1NNT4@1224|Proteobacteria,432A2@68525|delta/epsilon subdivisions,2WXUM@28221|Deltaproteobacteria,2MPG0@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
DYD2_k127_5329392_1	1121106.JQKB01000003_gene2555	2.635e-08	58.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,2JRSW@204441|Rhodospirillales	204441|Rhodospirillales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
DYD2_k127_5329392_0	861299.J421_2940	7.93e-87	306.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
DYD2_k127_5340679_0	1379270.AUXF01000001_gene2615	3.83e-79	280.0	COG0587@1|root,COG0587@2|Bacteria,1ZU9R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
DYD2_k127_5348866_2	1120954.ATXE01000001_gene1638	8.115e-124	403.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
DYD2_k127_5348866_5	1057002.KB905370_gene3326	2.322e-06	60.0	COG3467@1|root,COG3467@2|Bacteria,1NMEU@1224|Proteobacteria,2USRA@28211|Alphaproteobacteria,4BE5U@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
DYD2_k127_5348866_4	935863.AWZR01000005_gene2269	1.738e-49	183.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,1SBHQ@1236|Gammaproteobacteria,1X6JD@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
DYD2_k127_5348866_0	671143.DAMO_2812	3.388e-207	655.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
DYD2_k127_5348866_1	1452718.JBOY01000054_gene1977	5.097e-162	526.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_7
DYD2_k127_5348866_3	861299.J421_0541	1.992e-66	238.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	ycbU	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DYD2_k127_5351285_2	379066.GAU_1511	3.033e-96	321.0	COG0458@1|root,COG0458@2|Bacteria,1ZTAX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp
DYD2_k127_5351285_1	1032480.MLP_27670	1.413e-157	508.0	COG1181@1|root,COG1181@2|Bacteria,2IAF3@201174|Actinobacteria,4DVZ5@85009|Propionibacteriales	201174|Actinobacteria	M	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_4,CPSase_L_D2
DYD2_k127_5351285_0	402881.Plav_0542	3.404e-255	808.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2TR5K@28211|Alphaproteobacteria,1JN9I@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
DYD2_k127_5361160_2	448385.sce0740	3.004e-66	233.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2Z30P@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
DYD2_k127_5361160_1	1125863.JAFN01000001_gene942	5.464e-80	276.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,42RMI@68525|delta/epsilon subdivisions,2WNHS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,GTP_EFTU,PUA_2
DYD2_k127_5361160_3	926550.CLDAP_23740	1.374e-50	194.0	COG1218@1|root,COG1218@2|Bacteria	2|Bacteria	P	3'(2'),5'-bisphosphate nucleotidase activity	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
DYD2_k127_5361160_0	861299.J421_4163	2.284e-81	286.0	COG0795@1|root,COG0795@2|Bacteria,1ZSNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
DYD2_k127_5361160_4	880073.Calab_2502	3.595e-10	61.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
DYD2_k127_5366293_1	1121413.JMKT01000008_gene1216	8.156e-91	332.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WJ5T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg,dCache_1
DYD2_k127_5366293_2	146922.JOFU01000005_gene7158	5.56e-62	224.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	cutM	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
DYD2_k127_5366293_0	234267.Acid_2226	1.928e-173	556.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DYD2_k127_5387521_1	379066.GAU_3732	3.426e-16	87.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DYD2_k127_5387521_0	1121087.AUCK01000014_gene306	1.687e-16	88.0	COG4818@1|root,COG4818@2|Bacteria,1VBIZ@1239|Firmicutes,4HKBZ@91061|Bacilli,1ZJCH@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
DYD2_k127_5389668_5	1144275.COCOR_01323	3.077e-21	107.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
DYD2_k127_5389668_1	880073.Calab_2803	1.808e-196	632.0	COG0423@1|root,COG0423@2|Bacteria,2NNN9@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
DYD2_k127_5389668_4	867903.ThesuDRAFT_01471	1.591e-45	177.0	COG0584@1|root,COG0671@1|root,COG0584@2|Bacteria,COG0671@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WD9W@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,PAP2
DYD2_k127_5389668_2	1125863.JAFN01000001_gene1637	3.39e-105	353.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
DYD2_k127_5389668_3	861299.J421_2433	1.236e-59	233.0	COG2316@1|root,COG2316@2|Bacteria,1ZTH6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
DYD2_k127_5389668_0	869210.Marky_1642	7.832e-208	656.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
DYD2_k127_5397245_4	631454.N177_1477	2.18e-20	96.0	COG1268@1|root,COG1268@2|Bacteria,1RH78@1224|Proteobacteria,2U9DN@28211|Alphaproteobacteria,1JQ8W@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
DYD2_k127_5397245_3	861299.J421_3002	3.855e-105	355.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DYD2_k127_5397245_2	861299.J421_3003	7.172e-135	449.0	COG1960@1|root,COG1960@2|Bacteria,1ZSRC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
DYD2_k127_5397245_1	1379270.AUXF01000005_gene598	9.8e-141	458.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DYD2_k127_5397245_0	867903.ThesuDRAFT_01781	4.233e-164	535.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WCFT@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
DYD2_k127_539758_2	373903.Hore_04870	8.329e-33	144.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,3WAJM@53433|Halanaerobiales	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
DYD2_k127_539758_4	1210046.B277_10451	4.524e-11	76.0	COG1254@1|root,COG1254@2|Bacteria,2IQ4M@201174|Actinobacteria,4FHHA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
DYD2_k127_539758_0	861299.J421_1165	6.563e-99	337.0	COG1192@1|root,COG1192@2|Bacteria,1ZTH2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
DYD2_k127_539758_1	861299.J421_1167	1.281e-69	257.0	COG1475@1|root,COG1475@2|Bacteria,1ZSKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
DYD2_k127_539758_3	592031.GCWU000322_00867	3.466e-29	126.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,25W1V@186806|Eubacteriaceae	186801|Clostridia	D	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
DYD2_k127_539758_5	1242864.D187_002808	7.342e-10	67.0	COG1664@1|root,COG1664@2|Bacteria,1RHS7@1224|Proteobacteria	1224|Proteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
DYD2_k127_5407606_7	56107.Cylst_2090	2.138e-18	101.0	COG2234@1|root,COG2234@2|Bacteria,1G163@1117|Cyanobacteria,1HIM1@1161|Nostocales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
DYD2_k127_5407606_1	469383.Cwoe_2408	1.151e-154	503.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CRYD@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
DYD2_k127_5407606_11	700508.D174_23180	0.000357	50.0	COG3832@1|root,COG3832@2|Bacteria,2INRZ@201174|Actinobacteria,238K2@1762|Mycobacteriaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
DYD2_k127_5407606_6	1121931.AUHG01000012_gene2925	3.274e-19	101.0	COG1917@1|root,COG1917@2|Bacteria,4P2XE@976|Bacteroidetes,1IAY3@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5407606_8	657309.BXY_23040	7.796e-16	92.0	COG0642@1|root,COG0745@1|root,COG2207@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,4NITX@976|Bacteroidetes,2FM2F@200643|Bacteroidia,4ATFD@815|Bacteroidaceae	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
DYD2_k127_5407606_2	861299.J421_1360	7.047e-145	484.0	COG2132@1|root,COG2132@2|Bacteria,1ZUD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
DYD2_k127_5407606_0	1121904.ARBP01000029_gene2150	3.41e-240	793.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
DYD2_k127_5407606_5	709986.Deima_2673	3.251e-37	153.0	COG1505@1|root,COG1505@2|Bacteria	2|Bacteria	E	serine-type exopeptidase activity	pep	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
DYD2_k127_5407606_3	404589.Anae109_3542	6.15e-60	216.0	2DN8B@1|root,32W2U@2|Bacteria,1R03I@1224|Proteobacteria,42XCH@68525|delta/epsilon subdivisions,2WT8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5407606_9	518766.Rmar_2316	2.058e-11	78.0	COG4206@1|root,COG4206@2|Bacteria,4NZTH@976|Bacteroidetes,1FJS9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
DYD2_k127_5410435_2	497964.CfE428DRAFT_1240	2.742e-39	151.0	2DBEV@1|root,2Z8UT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5410435_1	497964.CfE428DRAFT_1241	2.886e-130	441.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	GH3
DYD2_k127_5410435_0	518766.Rmar_2129	1.91e-200	635.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1FIWI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DYD2_k127_5410435_3	1122939.ATUD01000004_gene3778	0.000557	53.0	COG1807@1|root,COG1807@2|Bacteria,2HNIC@201174|Actinobacteria,4CPHR@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
DYD2_k127_5431248_4	945713.IALB_0608	9.511e-36	143.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DYD2_k127_5431248_3	861299.J421_4395	2.664e-50	187.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
DYD2_k127_5431248_8	1237149.C900_00142	1.23e-05	57.0	COG4319@1|root,COG4319@2|Bacteria,4NSIN@976|Bacteroidetes,47SMM@768503|Cytophagia	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
DYD2_k127_5431248_5	290397.Adeh_4352	1.92e-22	105.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
DYD2_k127_5431248_1	1382359.JIAL01000001_gene1428	2.403e-95	325.0	COG0031@1|root,COG0031@2|Bacteria,3Y39M@57723|Acidobacteria,2JIQR@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
DYD2_k127_5431248_6	1122997.AUDD01000004_gene1332	1.423e-14	87.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
DYD2_k127_5431248_0	1303518.CCALI_00532	1.637e-165	533.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
DYD2_k127_5431248_7	330214.NIDE1191	3.649e-06	57.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	fn3
DYD2_k127_5431248_2	1122609.AUGT01000008_gene2868	1.198e-93	337.0	COG0366@1|root,COG0515@1|root,COG2133@1|root,COG3227@1|root,COG4733@1|root,COG0366@2|Bacteria,COG0515@2|Bacteria,COG2133@2|Bacteria,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.3	ko:K01178,ko:K14645,ko:K18546	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH15	-	Alpha-amylase,GSDH,He_PIG,PKD,Pro_Al_protease,SLH,Trypsin,fn3
DYD2_k127_5437759_6	266117.Rxyl_0053	1.38e-60	227.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CQA7@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
DYD2_k127_5437759_2	530564.Psta_2488	3.148e-152	495.0	COG0364@1|root,COG0364@2|Bacteria,2IXCV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
DYD2_k127_5437759_3	1489678.RDMS_11975	1.621e-121	398.0	COG1023@1|root,COG1023@2|Bacteria,1WIJ4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	NAD binding domain of 6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
DYD2_k127_5437759_4	926550.CLDAP_04910	8.227e-98	333.0	COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
DYD2_k127_5437759_8	666684.AfiDRAFT_0742	3.512e-37	146.0	294KR@1|root,2ZS06@2|Bacteria,1PAQ1@1224|Proteobacteria,2UXD4@28211|Alphaproteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5437759_5	861299.J421_3626	1.427e-61	228.0	COG5557@1|root,COG5557@2|Bacteria,1ZTCE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5437759_9	246197.MXAN_5554	7.101e-21	105.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
DYD2_k127_5437759_10	861299.J421_3628	2.199e-19	103.0	COG2010@1|root,COG2010@2|Bacteria,1ZTMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
DYD2_k127_5437759_1	316067.Geob_0866	1.302e-166	536.0	COG2010@1|root,COG5557@1|root,COG2010@2|Bacteria,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
DYD2_k127_5437759_0	861299.J421_3630	7.818e-210	695.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
DYD2_k127_5437759_7	1184267.A11Q_1512	5.265e-38	153.0	COG3303@1|root,COG3303@2|Bacteria,1QY22@1224|Proteobacteria,43C9D@68525|delta/epsilon subdivisions,2MTWU@213481|Bdellovibrionales,2WQ1C@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
DYD2_k127_5437759_11	517418.Ctha_1221	3.536e-16	92.0	2ECQK@1|root,336N8@2|Bacteria,1FEWY@1090|Chlorobi	1090|Chlorobi	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
DYD2_k127_5437759_13	1123507.ATVQ01000001_gene1631	1.363e-08	59.0	2BD34@1|root,326QM@2|Bacteria,2HC94@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5437759_14	1137268.AZXF01000026_gene2445	2.014e-07	61.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	catD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
DYD2_k127_5437759_12	518766.Rmar_2696	3.88e-15	82.0	COG2968@1|root,COG2968@2|Bacteria,4P8H6@976|Bacteroidetes,1FJN4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
DYD2_k127_5440558_0	204669.Acid345_3484	4.05e-132	438.0	COG0823@1|root,COG0823@2|Bacteria,3Y36H@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
DYD2_k127_5440558_2	1449350.OCH239_18060	6.631e-12	68.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,4KMB6@93682|Roseivivax	28211|Alphaproteobacteria	O	Scaffold protein Nfu/NifU N terminal	nifU	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
DYD2_k127_5440558_1	1123023.JIAI01000012_gene9200	1.353e-19	91.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,2GKVH@201174|Actinobacteria,4DYFA@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
DYD2_k127_5442956_0	391625.PPSIR1_25066	4.029e-96	323.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
DYD2_k127_5442956_2	713586.KB900536_gene628	0.0001802	52.0	COG0454@1|root,COG0456@2|Bacteria,1RKY5@1224|Proteobacteria,1S9I2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD2_k127_5442956_1	67275.JOAP01000042_gene7833	1.143e-59	218.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD2_k127_5446067_3	926560.KE387023_gene1505	1.878e-23	106.0	COG0613@1|root,COG0613@2|Bacteria,1WM4D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
DYD2_k127_5446067_1	644282.Deba_0596	9.095e-90	315.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
DYD2_k127_5446067_0	861299.J421_3918	8.155e-227	713.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
DYD2_k127_5446067_5	861299.J421_3920	7.59e-11	73.0	2F9BP@1|root,341NP@2|Bacteria,1ZTX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5446067_2	671143.DAMO_2903	2.47e-30	127.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
DYD2_k127_545824_0	1379270.AUXF01000001_gene2553	6.025e-184	591.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DYD2_k127_545824_4	1242864.D187_003878	1.752e-50	198.0	COG1409@1|root,COG1409@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
DYD2_k127_545824_2	861299.J421_4428	2.506e-143	469.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
DYD2_k127_545824_5	266117.Rxyl_0979	4.535e-14	75.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CP8S@84995|Rubrobacteria	84995|Rubrobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
DYD2_k127_545824_3	379066.GAU_0155	5.926e-101	341.0	COG0165@1|root,COG0165@2|Bacteria,1ZSM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
DYD2_k127_545824_1	861299.J421_1323	1.212e-151	494.0	COG0137@1|root,COG0137@2|Bacteria,1ZTYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
DYD2_k127_545824_6	591158.SSMG_01278	0.0002964	44.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DYD2_k127_5466239_0	1123322.KB904652_gene534	3.815e-18	92.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
DYD2_k127_5466239_1	264732.Moth_2247	7.962e-07	60.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,42FQC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
DYD2_k127_5470045_1	690850.Desaf_2099	0.0002032	51.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,2MB7Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
DYD2_k127_5470045_0	293826.Amet_1405	9.253e-90	309.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,36JNY@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
DYD2_k127_547143_0	562970.Btus_2147	3.464e-62	243.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,277XR@186823|Alicyclobacillaceae	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
DYD2_k127_547143_1	593750.Metfor_1905	6.571e-15	86.0	arCOG00805@1|root,arCOG00805@2157|Archaea,2XVHZ@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3857 ATP-dependent nuclease, subunit B	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
DYD2_k127_5490390_1	309807.SRU_0976	7.687e-16	91.0	COG0729@1|root,COG0729@2|Bacteria,4PF0B@976|Bacteroidetes,1FJXS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
DYD2_k127_549388_0	1379270.AUXF01000006_gene112	3.916e-160	510.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
DYD2_k127_549388_1	314256.OG2516_14930	6.999e-51	189.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2PDFD@252301|Oceanicola	28211|Alphaproteobacteria	I	Biotin carboxylase C-terminal domain	mccA	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
DYD2_k127_5550564_1	1123508.JH636441_gene3645	1.694e-51	185.0	COG2154@1|root,COG2154@2|Bacteria,2J0QH@203682|Planctomycetes	203682|Planctomycetes	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
DYD2_k127_5550564_0	472759.Nhal_1378	7.486e-62	230.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
DYD2_k127_5550564_2	68570.DC74_350	1.787e-21	102.0	COG1891@1|root,COG1891@2|Bacteria,2HKMX@201174|Actinobacteria	201174|Actinobacteria	S	lyase activity	-	-	4.2.3.153	ko:K09733	ko00680,map00680	-	R10935	RC03315	ko00000,ko00001,ko01000	-	-	-	4HFCP_synth
DYD2_k127_5563567_0	1382359.JIAL01000001_gene2326	3.998e-68	251.0	COG5002@1|root,COG5002@2|Bacteria,3Y3AX@57723|Acidobacteria,2JI3A@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_7
DYD2_k127_5563567_1	309807.SRU_0418	9.848e-11	72.0	COG3746@1|root,COG3746@2|Bacteria,4PEW5@976|Bacteroidetes,1FJQE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
DYD2_k127_563361_1	1158318.ATXC01000001_gene573	1.921e-83	283.0	COG0217@1|root,COG0217@2|Bacteria,2G3N5@200783|Aquificae	200783|Aquificae	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
DYD2_k127_563361_0	671143.DAMO_0568	2.32e-192	623.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
DYD2_k127_563361_2	1313172.YM304_21610	0.0003338	46.0	COG0705@1|root,COG0705@2|Bacteria,2GRXN@201174|Actinobacteria	201174|Actinobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5636911_0	264732.Moth_0675	1.097e-42	172.0	COG0507@1|root,COG0551@1|root,COG1112@1|root,COG1502@1|root,COG0507@2|Bacteria,COG0551@2|Bacteria,COG1112@2|Bacteria,COG1502@2|Bacteria,1UNF1@1239|Firmicutes,24HXY@186801|Clostridia	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,zf-C4_Topoisom
DYD2_k127_5649212_2	1123392.AQWL01000007_gene955	2.905e-71	267.0	COG2037@1|root,COG2037@2|Bacteria,1MVSD@1224|Proteobacteria,2VJSP@28216|Betaproteobacteria,1KSPB@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Formylmethanofuran-tetrahydromethanopterin formyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	FTR,FTR_C
DYD2_k127_5649212_0	765913.ThidrDRAFT_0560	4.894e-259	811.0	COG1229@1|root,COG1229@2|Bacteria,1NX13@1224|Proteobacteria,1RZ5G@1236|Gammaproteobacteria,1X07F@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM Formylmethanofuran dehydrogenase, subunit A	-	-	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
DYD2_k127_5649212_1	472759.Nhal_0015	3.339e-119	402.0	COG1029@1|root,COG1029@2|Bacteria,1R64R@1224|Proteobacteria,1RNM2@1236|Gammaproteobacteria,1X05Q@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM formylmethanofuran dehydrogenase subunit B	-	-	1.2.7.12	ko:K00201	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	-
DYD2_k127_5649212_3	1121033.AUCF01000014_gene1239	1.746e-22	113.0	COG2232@1|root,COG2232@2|Bacteria,1R6Y7@1224|Proteobacteria,2TRBR@28211|Alphaproteobacteria,2JSJ7@204441|Rhodospirillales	204441|Rhodospirillales	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
DYD2_k127_5651894_2	1449353.JQMQ01000005_gene4527	2.074e-84	314.0	COG0555@1|root,COG3842@1|root,COG0555@2|Bacteria,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE_2
DYD2_k127_5651894_6	379066.GAU_0983	1.087e-22	113.0	COG2261@1|root,COG2261@2|Bacteria,1ZU62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
DYD2_k127_5651894_3	1238182.C882_0401	2.934e-63	231.0	COG3616@1|root,COG3616@2|Bacteria,1N2SF@1224|Proteobacteria,2VFY5@28211|Alphaproteobacteria,2JRKP@204441|Rhodospirillales	204441|Rhodospirillales	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
DYD2_k127_5651894_0	1379270.AUXF01000004_gene3069	6.914e-129	432.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
DYD2_k127_5651894_1	1379270.AUXF01000004_gene3068	2.341e-91	321.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
DYD2_k127_5651894_4	1111479.AXAR01000006_gene737	1.837e-35	151.0	COG0725@1|root,COG0725@2|Bacteria,1V2FD@1239|Firmicutes	1239|Firmicutes	P	TIGRFAM tungstate ABC transporter binding protein WtpA	-	-	-	ko:K15495	ko02010,map02010	M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5	-	-	SBP_bac_11
DYD2_k127_5651894_7	1121346.KB899843_gene1028	6.313e-15	78.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,4HDWZ@91061|Bacilli,270CM@186822|Paenibacillaceae	91061|Bacilli	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DYD2_k127_565981_1	861299.J421_3204	2.905e-45	184.0	COG0127@1|root,COG0127@2|Bacteria,1ZTSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
DYD2_k127_565981_3	861299.J421_2404	3.041e-22	109.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_565981_0	1123242.JH636438_gene5687	1.573e-68	251.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
DYD2_k127_565981_2	1201288.M900_0274	7.875e-44	172.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,42RCU@68525|delta/epsilon subdivisions,2MT7P@213481|Bdellovibrionales,2WMXY@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
DYD2_k127_565981_4	1192124.LIG30_0198	2.299e-21	96.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VMNB@28216|Betaproteobacteria,1K1HE@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
DYD2_k127_5665835_1	1121930.AQXG01000001_gene1560	1.503e-51	195.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,1IQ46@117747|Sphingobacteriia	976|Bacteroidetes	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
DYD2_k127_5665835_0	861299.J421_2799	3.981e-118	394.0	COG0180@1|root,COG0180@2|Bacteria,1ZT3P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
DYD2_k127_5665835_2	1125863.JAFN01000001_gene1170	1.255e-27	122.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,42VSX@68525|delta/epsilon subdivisions,2WS1I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
DYD2_k127_566997_2	1380390.JIAT01000009_gene636	5.345e-37	141.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
DYD2_k127_566997_0	525897.Dbac_2687	1.602e-125	416.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2MA8W@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,BioW
DYD2_k127_566997_1	1382359.JIAL01000001_gene1783	1.934e-118	392.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria,2JIQ4@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DYD2_k127_568500_2	1121930.AQXG01000016_gene1818	5.28e-215	679.0	COG1757@1|root,COG1757@2|Bacteria,4NFF8@976|Bacteroidetes	976|Bacteroidetes	C	Na H anti-porter	mleN	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
DYD2_k127_568500_7	671143.DAMO_2491	6.531e-89	324.0	COG1028@1|root,COG1028@2|Bacteria,2NQBD@2323|unclassified Bacteria	2|Bacteria	IQ	NAD(P)H binding domain of trans-2-enoyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
DYD2_k127_568500_8	886293.Sinac_6000	7.635e-73	258.0	COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
DYD2_k127_568500_12	886379.AEWI01000032_gene2724	2.705e-51	204.0	COG2885@1|root,COG2885@2|Bacteria,4P236@976|Bacteroidetes	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DYD2_k127_568500_1	518766.Rmar_1231	9.791e-219	692.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1FIW6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
DYD2_k127_568500_16	234267.Acid_2602	1.405e-25	114.0	COG0457@1|root,COG0457@2|Bacteria,3Y893@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_568500_5	1227484.C471_09055	2.126e-107	365.0	COG3396@1|root,arCOG04786@2157|Archaea,2XU4A@28890|Euryarchaeota,23SMU@183963|Halobacteria	183963|Halobacteria	Q	Phenylacetate-CoA oxygenase subunit PaaA	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
DYD2_k127_568500_10	861299.J421_1828	2.182e-57	206.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
DYD2_k127_568500_4	96561.Dole_3137	5.425e-177	563.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2WKA6@28221|Deltaproteobacteria,2MJK5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
DYD2_k127_568500_14	1449357.JQLK01000001_gene1694	1.412e-32	130.0	COG2402@1|root,COG2402@2|Bacteria,1WJXN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
DYD2_k127_568500_19	477974.Daud_0414	8.59e-14	74.0	2DSVR@1|root,33HKS@2|Bacteria	2|Bacteria	L	CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1,RHH_3,RHH_4
DYD2_k127_568500_21	472759.Nhal_3484	6.897e-06	51.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
DYD2_k127_568500_20	665959.HMPREF1013_03078	3.838e-06	54.0	COG0664@1|root,COG0664@2|Bacteria,1UAFX@1239|Firmicutes,4IKUA@91061|Bacilli,1ZHM7@1386|Bacillus	91061|Bacilli	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_568500_6	861299.J421_1827	1.774e-98	330.0	COG0515@1|root,COG0515@2|Bacteria,1ZUHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
DYD2_k127_568500_13	1089550.ATTH01000001_gene1831	3.406e-35	153.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
DYD2_k127_568500_18	1448389.BAVQ01000043_gene1922	2.95e-22	113.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
DYD2_k127_568500_15	1265313.HRUBRA_01348	1.637e-32	143.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
DYD2_k127_568500_9	357808.RoseRS_3278	1.181e-57	217.0	COG2197@1|root,COG2197@2|Bacteria,2G8NX@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DYD2_k127_568500_11	357808.RoseRS_3277	1.279e-51	192.0	COG4585@1|root,COG4585@2|Bacteria,2G8N5@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
DYD2_k127_568500_3	869210.Marky_1224	4.521e-198	625.0	COG2224@1|root,COG2224@2|Bacteria,1WI8Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
DYD2_k127_568500_0	861299.J421_3036	2.275e-223	708.0	COG2224@1|root,COG2225@1|root,COG2224@2|Bacteria,COG2225@2|Bacteria	2|Bacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	aceB	GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010	Malate_synthase
DYD2_k127_5685073_1	518766.Rmar_1830	9.318e-120	411.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes,1FK1K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DYD2_k127_5685073_0	335543.Sfum_0829	2.151e-122	402.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2MREJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
DYD2_k127_5716254_1	265729.GS18_0211595	4.549e-21	101.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,1ZCTF@1386|Bacillus	91061|Bacilli	O	COG1030 Membrane-bound serine protease (ClpP class)	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
DYD2_k127_5716254_0	1379698.RBG1_1C00001G0806	1.45e-122	399.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
DYD2_k127_5716254_2	518766.Rmar_2301	6.695e-05	56.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_2301|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_571924_0	861299.J421_2380	2.087e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,1ZSWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_571924_1	330214.NIDE1608	1.743e-17	91.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
DYD2_k127_571924_2	525897.Dbac_1533	3.783e-08	65.0	COG0296@1|root,COG0296@2|Bacteria,1NEFK@1224|Proteobacteria,42VRH@68525|delta/epsilon subdivisions,2WRD5@28221|Deltaproteobacteria,2MC6U@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
DYD2_k127_5725477_1	944435.AXAJ01000007_gene1508	1.868e-33	137.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2VRQA@28216|Betaproteobacteria,1K202@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
DYD2_k127_5725477_0	186497.PF0440	2.062e-52	209.0	COG0209@1|root,COG1372@1|root,arCOG03154@1|root,arCOG03151@2157|Archaea,arCOG03154@2157|Archaea,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,243K4@183968|Thermococci	183968|Thermococci	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Endonuc_subdom,Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,Stirrup
DYD2_k127_5734544_0	309801.trd_A0017	5.264e-67	235.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
DYD2_k127_5734544_2	886293.Sinac_3762	1.655e-38	163.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,2IZ1I@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
DYD2_k127_5734544_1	1089550.ATTH01000001_gene1586	5.176e-45	173.0	COG4221@1|root,COG4221@2|Bacteria,4NTKP@976|Bacteroidetes	976|Bacteroidetes	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
DYD2_k127_5735733_3	1110502.TMO_3058	5.823e-06	58.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2TQRS@28211|Alphaproteobacteria,2JPFZ@204441|Rhodospirillales	204441|Rhodospirillales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
DYD2_k127_5735733_1	269084.syc2102_c	2.329e-57	211.0	COG4229@1|root,COG4229@2|Bacteria,1G59P@1117|Cyanobacteria,1H3Y4@1129|Synechococcus	1117|Cyanobacteria	F	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	-	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
DYD2_k127_5735733_0	530564.Psta_3140	4.729e-67	238.0	COG1791@1|root,COG1791@2|Bacteria,2J2NB@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
DYD2_k127_5735733_2	1173264.KI913949_gene709	4.169e-34	136.0	COG0235@1|root,COG0235@2|Bacteria,1G2EA@1117|Cyanobacteria,1H8JN@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
DYD2_k127_574213_0	1128421.JAGA01000002_gene868	4.563e-43	167.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	mgsA	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat,DSPc,MGS
DYD2_k127_574213_1	1415780.JPOG01000001_gene3311	1.206e-35	147.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1XCI1@135614|Xanthomonadales	135614|Xanthomonadales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
DYD2_k127_5743422_1	861299.J421_1300	5.161e-27	114.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DYD2_k127_5743422_2	452662.SJA_C1-33550	5.657e-13	81.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,2UCR7@28211|Alphaproteobacteria,2K5MQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
DYD2_k127_5743422_0	395495.Lcho_1731	2.597e-53	198.0	COG2199@1|root,COG3290@1|root,COG2199@2|Bacteria,COG3290@2|Bacteria,1RGCV@1224|Proteobacteria,2VQEF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4
DYD2_k127_5747616_4	861299.J421_3345	0.0008989	42.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
DYD2_k127_5747616_2	880073.Calab_1746	1.786e-35	140.0	2CIU6@1|root,32S8H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5747616_1	1122223.KB890687_gene2975	5.255e-54	200.0	COG1024@1|root,COG1024@2|Bacteria,1WIUH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
DYD2_k127_5747616_3	596151.DesfrDRAFT_2319	0.0008198	50.0	2C46F@1|root,32SRD@2|Bacteria,1N540@1224|Proteobacteria,42UJ6@68525|delta/epsilon subdivisions,2WQUS@28221|Deltaproteobacteria,2MBJ9@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5747616_0	1379270.AUXF01000006_gene190	8.348e-89	308.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
DYD2_k127_5748629_1	1122223.KB890700_gene2009	1.037e-27	121.0	COG0683@1|root,COG0834@1|root,COG0683@2|Bacteria,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Peripla_BP_6,SBP_bac_3,SDF
DYD2_k127_5748629_0	861299.J421_1952	3.601e-90	313.0	COG3391@1|root,COG3391@2|Bacteria,1ZU68@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5760865_3	379066.GAU_0968	3.344e-98	334.0	COG3550@1|root,COG3550@2|Bacteria	2|Bacteria	S	kinase activity	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
DYD2_k127_5760865_8	379066.GAU_0969	2.22e-19	92.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
DYD2_k127_5760865_4	298654.FraEuI1c_0484	2.369e-33	150.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4EU0N@85013|Frankiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	lpqC	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
DYD2_k127_5760865_2	502025.Hoch_0385	1.513e-125	426.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales	28221|Deltaproteobacteria	F	adenosine deaminase	-	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
DYD2_k127_5760865_5	204669.Acid345_2164	3.001e-32	134.0	COG2318@1|root,COG2318@2|Bacteria,3Y501@57723|Acidobacteria,2JJGU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
DYD2_k127_5760865_0	861299.J421_3134	1.689e-174	573.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
DYD2_k127_5760865_7	745718.JADT01000014_gene128	1.179e-25	123.0	2ETTP@1|root,33MB1@2|Bacteria,4NZFX@976|Bacteroidetes,1I6T5@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5760865_1	861299.J421_0420	8.144e-165	526.0	COG2170@1|root,COG2170@2|Bacteria,1ZTBN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
DYD2_k127_5760865_6	1385518.N798_15465	1.056e-29	126.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria,4FIIB@85021|Intrasporangiaceae	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
DYD2_k127_5769786_1	1122604.JONR01000004_gene851	1.43e-68	257.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,1X903@135614|Xanthomonadales	135614|Xanthomonadales	S	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
DYD2_k127_5769786_2	861299.J421_2228	1.241e-60	220.0	COG0702@1|root,COG0702@2|Bacteria,1ZV6Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
DYD2_k127_5769786_0	234267.Acid_7338	1.109e-139	459.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DYD2_k127_5818165_0	1123368.AUIS01000001_gene1896	3.902e-233	731.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1SJQ1@1236|Gammaproteobacteria,2NDRU@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
DYD2_k127_5818165_2	1123242.JH636434_gene3809	7.931e-50	199.0	COG0698@1|root,COG0698@2|Bacteria,2IZSB@203682|Planctomycetes	203682|Planctomycetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
DYD2_k127_5818165_1	247490.KSU1_C1633	2.182e-230	748.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2IY2M@203682|Planctomycetes	203682|Planctomycetes	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
DYD2_k127_5850510_0	986075.CathTA2_1975	4.817e-139	460.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
DYD2_k127_5852738_0	1049564.TevJSym_ac00600	2.503e-159	541.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
DYD2_k127_5852738_1	247490.KSU1_C1314	6.477e-87	324.0	COG0535@1|root,COG0535@2|Bacteria,2J2KS@203682|Planctomycetes	203682|Planctomycetes	S	Proto-chlorophyllide reductase 57 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	PCP_red,Radical_SAM,SPASM
DYD2_k127_5852738_2	266117.Rxyl_0436	1.274e-74	277.0	COG0589@1|root,COG1592@1|root,COG1773@1|root,COG0589@2|Bacteria,COG1592@2|Bacteria,COG1773@2|Bacteria	2|Bacteria	C	rubredoxin	hrb	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavin_Reduct,Lactamase_B,Rubredoxin,Rubrerythrin,Usp
DYD2_k127_5853604_1	1122611.KB903968_gene2299	1.223e-19	90.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria,4EJ8K@85012|Streptosporangiales	201174|Actinobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	srsB	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
DYD2_k127_5853604_2	1278073.MYSTI_07227	3.84e-07	58.0	COG0236@1|root,COG0236@2|Bacteria,1QAHP@1224|Proteobacteria,4353G@68525|delta/epsilon subdivisions,2WZEI@28221|Deltaproteobacteria,2Z1YW@29|Myxococcales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
DYD2_k127_5853604_0	215803.DB30_1640	6.341e-95	328.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria,2YUJE@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
DYD2_k127_5896157_0	1254432.SCE1572_51690	5.111e-82	290.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,2YUHA@29|Myxococcales	28221|Deltaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
DYD2_k127_5896157_1	314278.NB231_10163	2.687e-25	114.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,1SA77@1236|Gammaproteobacteria,1X22S@135613|Chromatiales	135613|Chromatiales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
DYD2_k127_5898295_0	861299.J421_3441	5.372e-167	541.0	COG1418@1|root,COG1418@2|Bacteria,1ZT0I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
DYD2_k127_5898295_2	861299.J421_3440	8.726e-105	350.0	COG0190@1|root,COG0190@2|Bacteria,1ZSVX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
DYD2_k127_5898295_1	861299.J421_3439	1.368e-108	366.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
DYD2_k127_5898295_5	555079.Toce_1309	6.055e-06	58.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,42HHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
DYD2_k127_5898295_3	861299.J421_3437	4.063e-72	257.0	COG0142@1|root,COG0142@2|Bacteria,1ZSR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
DYD2_k127_5898295_4	861299.J421_3435	2.255e-68	254.0	COG0061@1|root,COG0061@2|Bacteria,1ZT32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
DYD2_k127_5901607_1	861299.J421_3401	6.481e-198	629.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DYD2_k127_5901607_3	379066.GAU_1764	3.761e-68	235.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
DYD2_k127_5901607_5	944480.ATUV01000002_gene316	2.296e-26	113.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2M7C8@213113|Desulfurellales	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
DYD2_k127_5901607_2	861299.J421_3191	4.573e-83	299.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
DYD2_k127_5901607_4	562970.Btus_1544	2.264e-51	198.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,278AP@186823|Alicyclobacillaceae	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
DYD2_k127_5901607_6	1266909.AUAG01000007_gene2368	1.034e-21	100.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales	135613|Chromatiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
DYD2_k127_5901607_7	525904.Tter_1743	7.211e-09	60.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
DYD2_k127_5901607_0	945713.IALB_0639	1.314e-208	668.0	COG0532@1|root,COG0532@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
DYD2_k127_5913726_0	1304275.C41B8_15205	1.367e-142	470.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,1RPTS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
DYD2_k127_5913726_2	879212.DespoDRAFT_02724	3.572e-07	63.0	COG2044@1|root,COG2044@2|Bacteria,1RK3U@1224|Proteobacteria,42SYH@68525|delta/epsilon subdivisions,2WPGT@28221|Deltaproteobacteria,2MK3I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
DYD2_k127_5913726_1	1121033.AUCF01000046_gene548	6.694e-49	179.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,2JSK7@204441|Rhodospirillales	204441|Rhodospirillales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
DYD2_k127_5926471_0	909663.KI867150_gene944	9.549e-171	546.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2MQA7@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
DYD2_k127_5926471_1	1379270.AUXF01000005_gene738	1.211e-40	156.0	COG1259@1|root,COG1259@2|Bacteria,1ZTKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
DYD2_k127_5926471_2	861299.J421_3130	5.905e-20	102.0	COG2010@1|root,COG2010@2|Bacteria,1ZT9T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_5938011_2	861299.J421_3143	1.235e-37	158.0	COG0044@1|root,COG0044@2|Bacteria,1ZT4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
DYD2_k127_5938011_0	861299.J421_3142	8.378e-157	519.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
DYD2_k127_5938011_1	379066.GAU_1514	2.498e-43	173.0	COG2065@1|root,COG2065@2|Bacteria,1ZTHG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
DYD2_k127_5991617_2	682795.AciX8_1320	6.159e-08	60.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
DYD2_k127_5991617_0	339860.Msp_0035	8.05e-55	198.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,23P0H@183925|Methanobacteria	183925|Methanobacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
DYD2_k127_5991617_1	1379270.AUXF01000004_gene3272	7.134e-15	79.0	2A0X4@1|root,30P27@2|Bacteria,1ZUWS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6009313_0	861299.J421_3994	2.304e-66	247.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	lpoB	GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K07337,ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	LpoB
DYD2_k127_6016665_1	338963.Pcar_1870	1.563e-77	279.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43S4Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
DYD2_k127_6016665_2	338963.Pcar_1870	9.998e-69	265.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43S4Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
DYD2_k127_6016665_0	1519464.HY22_02230	3.686e-94	323.0	COG0601@1|root,COG0601@2|Bacteria,1FDDB@1090|Chlorobi	1090|Chlorobi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
DYD2_k127_6018603_9	1137268.AZXF01000011_gene3718	2.86e-18	91.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria,4EKQY@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
DYD2_k127_6018603_7	661478.OP10G_3830	5.942e-28	122.0	COG1956@1|root,COG1956@2|Bacteria	2|Bacteria	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
DYD2_k127_6018603_1	926560.KE387028_gene161	1.69e-103	352.0	COG0428@1|root,COG0428@2|Bacteria,1WM75@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6018603_0	1121939.L861_22265	1.908e-117	388.0	COG2132@1|root,COG2132@2|Bacteria,1R8SR@1224|Proteobacteria,1SDTA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
DYD2_k127_6018603_5	1179773.BN6_06160	9.033e-46	172.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4E1BA@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
DYD2_k127_6018603_10	1380355.JNIJ01000007_gene3288	3.509e-05	55.0	COG3832@1|root,COG3832@2|Bacteria,1R428@1224|Proteobacteria,2U6AP@28211|Alphaproteobacteria,3K3YI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
DYD2_k127_6018603_2	1128421.JAGA01000001_gene2365	7.892e-94	319.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
DYD2_k127_6018603_4	1128427.KB904821_gene3775	3.436e-75	260.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,1H8MW@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
DYD2_k127_6018603_3	28072.Nos7524_2763	1.226e-88	321.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1GC0N@1117|Cyanobacteria,1HR0M@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
DYD2_k127_6018603_8	751945.Theos_2102	4.03e-21	107.0	COG3824@1|root,COG3824@2|Bacteria,1WJSP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
DYD2_k127_6018603_6	1238182.C882_3985	5.648e-28	120.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,2JT3C@204441|Rhodospirillales	204441|Rhodospirillales	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
DYD2_k127_603127_1	266117.Rxyl_2978	1.449e-31	131.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
DYD2_k127_603127_2	379066.GAU_1186	3.702e-15	83.0	COG3679@1|root,COG3679@2|Bacteria,1ZTRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
DYD2_k127_603127_0	644282.Deba_0738	7.963e-43	167.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
DYD2_k127_6048163_0	1089550.ATTH01000001_gene1831	1.818e-129	446.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
DYD2_k127_6048163_2	1089550.ATTH01000001_gene2237	2.309e-45	173.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DYD2_k127_6048163_3	234267.Acid_1209	3.164e-41	165.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
DYD2_k127_6048163_1	861299.J421_1827	8.844e-53	198.0	COG0515@1|root,COG0515@2|Bacteria,1ZUHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
DYD2_k127_6055017_0	1379270.AUXF01000005_gene790	2.876e-182	577.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
DYD2_k127_6055017_3	59374.Fisuc_0060	1.882e-32	129.0	COG0234@1|root,COG0234@2|Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
DYD2_k127_6055017_2	1121946.AUAX01000006_gene3597	5.282e-47	192.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4D9W0@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
DYD2_k127_6055017_4	498761.HM1_0663	2.53e-31	141.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
DYD2_k127_6055017_1	1449080.JQMV01000003_gene1103	2.288e-78	272.0	COG0157@1|root,COG0157@2|Bacteria,1WIHZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
DYD2_k127_6064714_1	638303.Thal_0595	1.844e-33	133.0	COG0537@1|root,COG0537@2|Bacteria,2G44F@200783|Aquificae	200783|Aquificae	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
DYD2_k127_6064714_0	1379270.AUXF01000006_gene68	1.384e-108	374.0	COG1193@1|root,COG1193@2|Bacteria,1ZSWM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
DYD2_k127_6076393_0	861299.J421_2948	3.764e-135	459.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
DYD2_k127_6076393_2	379066.GAU_1196	1.673e-16	95.0	COG3087@1|root,COG3087@2|Bacteria,1ZSYS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
DYD2_k127_6076393_1	861299.J421_2945	5.618e-83	286.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
DYD2_k127_6077596_0	1089550.ATTH01000001_gene237	5.731e-154	509.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
DYD2_k127_6077596_1	1151061.CAJY01000017_gene250	6.992e-81	293.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA2	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
DYD2_k127_6077596_2	926560.KE387023_gene2058	6.685e-36	143.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
DYD2_k127_6077596_3	926550.CLDAP_21910	4.932e-15	78.0	COG3631@1|root,COG3631@2|Bacteria,2G75M@200795|Chloroflexi	200795|Chloroflexi	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
DYD2_k127_6079867_0	861299.J421_2927	2.297e-149	496.0	COG0621@1|root,COG0621@2|Bacteria,1ZT70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
DYD2_k127_6079867_1	379066.GAU_1190	1.067e-22	106.0	COG2834@1|root,COG2834@2|Bacteria,1ZTXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
DYD2_k127_6080727_3	861299.J421_3390	1.077e-19	93.0	COG0442@1|root,COG0442@2|Bacteria,1ZT48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
DYD2_k127_6080727_0	379066.GAU_1750	8.781e-222	705.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1ZSMF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
DYD2_k127_6080727_1	497964.CfE428DRAFT_0749	6.909e-70	245.0	COG0327@1|root,COG0327@2|Bacteria	2|Bacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	ybgI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
DYD2_k127_6080727_5	1392498.JQLH01000001_gene1496	3.474e-17	95.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia,2PG7R@252356|Maribacter	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
DYD2_k127_6080727_2	861299.J421_2625	8.595e-62	222.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
DYD2_k127_6080727_4	570952.ATVH01000011_gene611	2.591e-17	88.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2JPB2@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
DYD2_k127_6084790_0	379066.GAU_0014	5.688e-143	467.0	COG2270@1|root,COG2270@2|Bacteria,1ZSZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
DYD2_k127_6084790_1	1144275.COCOR_06255	6.43e-12	74.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
DYD2_k127_612164_5	882083.SacmaDRAFT_3588	1.142e-19	97.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
DYD2_k127_612164_3	96561.Dole_0814	3.188e-36	151.0	COG2253@1|root,COG2253@2|Bacteria,1R66E@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	ko:K09144	-	-	-	-	ko00000	-	-	-	AbiEii,WYL
DYD2_k127_612164_2	416591.Tlet_1204	4.187e-46	177.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4,DUF559
DYD2_k127_612164_1	682795.AciX8_1476	2.16e-53	214.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	PMT_2
DYD2_k127_612164_4	621372.ACIH01000041_gene342	3.699e-34	153.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,4HDKY@91061|Bacilli,26U9S@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl transferase family 2	ycbB	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
DYD2_k127_612164_0	56110.Oscil6304_3528	3.511e-122	409.0	COG0451@1|root,COG0451@2|Bacteria,1G0QH@1117|Cyanobacteria,1H7R6@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,5.1.3.2	ko:K01784,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
DYD2_k127_612164_6	251229.Chro_1070	2.435e-19	100.0	COG2120@1|root,COG2120@2|Bacteria,1G5JP@1117|Cyanobacteria,3VKVH@52604|Pleurocapsales	1117|Cyanobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DYD2_k127_613603_1	448385.sce6608	2.264e-55	207.0	COG3386@1|root,COG3386@2|Bacteria,1MXB7@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
DYD2_k127_613603_2	1122132.AQYH01000002_gene1242	1.079e-13	85.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9US@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Guanylate_cyc,TPR_14,TPR_16
DYD2_k127_613603_0	861299.J421_5759	4.232e-84	311.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DYD2_k127_6146601_5	1082705.JIBP01000015_gene1167	8.362e-06	58.0	28HSZ@1|root,2Z7ZZ@2|Bacteria,1PKZD@1224|Proteobacteria,1RY25@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6146601_2	1192034.CAP_1726	6.64e-51	196.0	COG2267@1|root,COG2267@2|Bacteria,1NYNM@1224|Proteobacteria,43CA0@68525|delta/epsilon subdivisions,2X7KG@28221|Deltaproteobacteria,2YVW6@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
DYD2_k127_6146601_1	861299.J421_1183	7.69e-63	246.0	COG0429@1|root,COG0429@2|Bacteria,1ZSTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
DYD2_k127_6146601_0	861299.J421_2864	1.778e-121	428.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
DYD2_k127_6146601_3	861299.J421_3625	9.927e-36	156.0	COG3118@1|root,COG3118@2|Bacteria,1ZV4B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
DYD2_k127_6146601_4	1128421.JAGA01000003_gene3734	8.18e-15	84.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
DYD2_k127_6151535_1	518766.Rmar_1291	3.502e-40	156.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1FJA0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
DYD2_k127_6151535_0	379066.GAU_1789	2.91e-246	777.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
DYD2_k127_6160866_2	243231.GSU2323	2.693e-54	203.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,42R9G@68525|delta/epsilon subdivisions,2WMTN@28221|Deltaproteobacteria,43TRU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
DYD2_k127_6160866_0	472759.Nhal_1374	8.772e-172	557.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
DYD2_k127_6160866_1	861299.J421_3474	9.692e-64	231.0	COG4448@1|root,COG4448@2|Bacteria,1ZTG2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
DYD2_k127_6164470_0	1379698.RBG1_1C00001G0805	7.541e-186	601.0	COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
DYD2_k127_6164470_1	644966.Tmar_2129	5.057e-75	257.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WCX5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
DYD2_k127_6167357_1	1499967.BAYZ01000190_gene3858	1.431e-70	250.0	COG1030@1|root,COG1030@2|Bacteria,2NNMU@2323|unclassified Bacteria	2|Bacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,Peptidase_S49,SDH_sah
DYD2_k127_6167357_0	670487.Ocepr_1193	3.629e-126	414.0	COG4864@1|root,COG4864@2|Bacteria,1WI32@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
DYD2_k127_6185857_3	290397.Adeh_2884	1.07e-111	371.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,42SJR@68525|delta/epsilon subdivisions,2WRRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
DYD2_k127_6185857_5	1121920.AUAU01000012_gene2613	1.493e-25	108.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
DYD2_k127_6185857_2	1415754.JQMK01000012_gene914	2.786e-148	487.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,466AY@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6185857_1	880072.Desac_1601	1.245e-224	754.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
DYD2_k127_6185857_0	1158182.KB905026_gene287	3.5e-323	1033.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WXV4@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
DYD2_k127_6185857_4	1323663.AROI01000014_gene131	3.743e-42	169.0	COG0845@1|root,COG0845@2|Bacteria,1RD8U@1224|Proteobacteria,1S527@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DYD2_k127_62044_4	1137268.AZXF01000009_gene3988	9.5e-20	93.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4EFG2@85012|Streptosporangiales	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
DYD2_k127_62044_3	1121430.JMLG01000021_gene1384	3.876e-30	132.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,262DJ@186807|Peptococcaceae	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
DYD2_k127_62044_2	379066.GAU_2461	1.118e-63	246.0	COG2027@1|root,COG2027@2|Bacteria,1ZSQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
DYD2_k127_62044_1	1131269.AQVV01000004_gene645	2.412e-84	306.0	COG0303@1|root,COG0303@2|Bacteria	2|Bacteria	H	'Molybdopterin	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
DYD2_k127_62044_0	187272.Mlg_1158	6.979e-93	332.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria,1X0JQ@135613|Chromatiales	135613|Chromatiales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6248451_2	158500.BV97_00371	0.0001618	50.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2U0G1@28211|Alphaproteobacteria,2K2GZ@204457|Sphingomonadales	204457|Sphingomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
DYD2_k127_6248451_0	760192.Halhy_3056	3.227e-43	173.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1IP3Q@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
DYD2_k127_6248451_3	429009.Adeg_1035	0.0001933	51.0	COG3847@1|root,COG3847@2|Bacteria,1VKJ4@1239|Firmicutes,24UMJ@186801|Clostridia,42HJV@68295|Thermoanaerobacterales	186801|Clostridia	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
DYD2_k127_6248451_1	1460635.JCM19038_1556	4.738e-05	55.0	COG3847@1|root,COG3847@2|Bacteria,1VKJ4@1239|Firmicutes	1239|Firmicutes	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
DYD2_k127_6267512_8	269799.Gmet_1549	1.881e-29	132.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42Q6P@68525|delta/epsilon subdivisions,2X5QT@28221|Deltaproteobacteria,43TVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DYD2_k127_6267512_6	926560.KE387025_gene3970	2.597e-39	149.0	COG4633@1|root,COG4633@2|Bacteria,1WMVC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
DYD2_k127_6267512_0	604331.AUHY01000107_gene1761	1.088e-304	956.0	COG2217@1|root,COG2217@2|Bacteria,1WJ55@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,HMA,Hydrolase
DYD2_k127_6267512_3	1198452.Jab_2c15020	5.564e-68	249.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,2VI30@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HAMP,HATPase_c,HisKA
DYD2_k127_6267512_2	314345.SPV1_12687	6.993e-72	263.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria	1224|Proteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
DYD2_k127_6267512_5	379066.GAU_2909	1.076e-39	163.0	COG4319@1|root,COG4319@2|Bacteria,1ZUN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6267512_9	330214.NIDE3675	3.727e-19	99.0	2DKWD@1|root,30KRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
DYD2_k127_6267512_7	1379270.AUXF01000003_gene3644	8.029e-39	156.0	COG2885@1|root,COG2885@2|Bacteria,1ZTR2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
DYD2_k127_6267512_1	1382359.JIAL01000001_gene2095	3.894e-132	436.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
DYD2_k127_6267512_4	379066.GAU_2191	2.234e-67	257.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07711,ko:K14980,ko:K18143	ko01501,ko02020,ko02024,map01501,map02020,map02024	M00502,M00520,M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,MFS_1,dCache_1
DYD2_k127_6269480_3	688245.CtCNB1_2063	1.777e-56	214.0	COG1541@1|root,COG1541@2|Bacteria,1QZDY@1224|Proteobacteria,2VIX3@28216|Betaproteobacteria,4ABQT@80864|Comamonadaceae	28216|Betaproteobacteria	H	Acyl-protein synthetase, LuxE	-	-	6.2.1.19	ko:K06046	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	LuxE
DYD2_k127_6269480_6	1184251.TCELL_0982	4.27e-08	66.0	COG0265@1|root,arCOG02833@2157|Archaea,2XQ4X@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
DYD2_k127_6269480_7	1379270.AUXF01000001_gene2410	4.689e-05	55.0	2F7PW@1|root,34048@2|Bacteria,1ZTZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6269480_4	204669.Acid345_2486	3.534e-42	165.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria,2JHY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_6269480_5	861299.J421_0797	3.976e-34	151.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	dgkA	-	2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K00901,ko:K01096,ko:K19302	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02029,R02240,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_2369	DAGK_prokar,PAP2,PAP2_3
DYD2_k127_6269480_2	42256.RradSPS_2789	2.474e-83	293.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria	201174|Actinobacteria	M	3-beta hydroxysteroid dehydrogenase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
DYD2_k127_6269480_1	1379698.RBG1_1C00001G0533	1.674e-100	357.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
DYD2_k127_6269480_0	861299.J421_0795	3.198e-139	458.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	2|Bacteria	H	Beta-eliminating lyase	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
DYD2_k127_6271466_1	379066.GAU_2144	2.199e-220	730.0	COG1217@1|root,COG1217@2|Bacteria,1ZT8A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
DYD2_k127_6271466_5	706587.Desti_1672	4.802e-33	144.0	COG0432@1|root,COG0432@2|Bacteria,1N5SN@1224|Proteobacteria,42SJC@68525|delta/epsilon subdivisions,2WP9F@28221|Deltaproteobacteria,2MRXI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
DYD2_k127_6271466_6	319236.JCM19294_2707	0.0008533	51.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,1HY6H@117743|Flavobacteriia,3HJKT@363408|Nonlabens	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
DYD2_k127_6271466_0	379066.GAU_0737	0.0	1305.0	COG0587@1|root,COG0587@2|Bacteria,1ZT8N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
DYD2_k127_6271466_3	717605.Theco_2617	4.054e-104	347.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,26RG8@186822|Paenibacillaceae	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
DYD2_k127_6271466_4	861299.J421_2654	4.882e-84	287.0	COG1774@1|root,COG1774@2|Bacteria,1ZTE8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
DYD2_k127_6271466_2	891968.Anamo_0461	2.258e-130	433.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3T9XI@508458|Synergistetes	508458|Synergistetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
DYD2_k127_6324711_0	1121438.JNJA01000013_gene79	1.811e-38	155.0	COG0697@1|root,COG0697@2|Bacteria,1RJFE@1224|Proteobacteria,42STE@68525|delta/epsilon subdivisions,2WP7Z@28221|Deltaproteobacteria,2MAAW@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
DYD2_k127_6329023_1	1173029.JH980292_gene1261	1.253e-47	178.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria,1H88V@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
DYD2_k127_6329023_0	1173029.JH980292_gene1261	3.14e-223	705.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria,1H88V@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
DYD2_k127_6371252_4	379066.GAU_0192	1.474e-97	334.0	COG0075@1|root,COG0075@2|Bacteria,1ZTF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
DYD2_k127_6371252_1	290397.Adeh_1262	3.989e-120	408.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,42R07@68525|delta/epsilon subdivisions,2X7JR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
DYD2_k127_6371252_0	251221.35214007	1.133e-133	452.0	COG4638@1|root,COG4638@2|Bacteria,1G6W8@1117|Cyanobacteria	1117|Cyanobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
DYD2_k127_6371252_6	266117.Rxyl_3164	1.145e-67	247.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
DYD2_k127_6371252_8	926550.CLDAP_22580	9.996e-16	88.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
DYD2_k127_6371252_7	266117.Rxyl_0743	3.782e-24	115.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
DYD2_k127_6371252_5	743719.PaelaDRAFT_2487	1.897e-71	249.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26Q92@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
DYD2_k127_6371252_3	1125971.ASJB01000031_gene1284	6.384e-109	362.0	COG1830@1|root,COG1830@2|Bacteria,2HPYY@201174|Actinobacteria,4E70X@85010|Pseudonocardiales	201174|Actinobacteria	G	Aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
DYD2_k127_6371252_2	1040989.AWZU01000100_gene7350	1.091e-117	403.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,3JU44@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6375628_0	861299.J421_3884	1.744e-60	215.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_6375628_3	467661.RKLH11_2176	8.183e-06	57.0	2BGF0@1|root,32ACV@2|Bacteria,1RI61@1224|Proteobacteria,2U9WW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
DYD2_k127_6375628_2	1463934.JOCF01000137_gene5034	3.277e-09	69.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria,2HITU@201174|Actinobacteria	201174|Actinobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
DYD2_k127_6379123_0	861299.J421_3747	2.077e-301	956.0	COG1197@1|root,COG1197@2|Bacteria,1ZT88@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
DYD2_k127_6379123_1	404589.Anae109_4481	2.078e-07	63.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,2YVIS@29|Myxococcales	28221|Deltaproteobacteria	M	SurA N-terminal domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
DYD2_k127_6384062_6	562970.Btus_3255	1.696e-17	88.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,278FR@186823|Alicyclobacillaceae	91061|Bacilli	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
DYD2_k127_6384062_1	665571.STHERM_c19280	5.879e-125	410.0	COG0216@1|root,COG0216@2|Bacteria,2J5KY@203691|Spirochaetes	203691|Spirochaetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
DYD2_k127_6384062_5	573413.Spirs_3178	2.117e-24	109.0	COG0254@1|root,COG0254@2|Bacteria,2J93Z@203691|Spirochaetes	203691|Spirochaetes	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
DYD2_k127_6384062_4	861299.J421_1231	1.52e-46	192.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_1231|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
DYD2_k127_6384062_0	861299.J421_2864	1.774e-133	440.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
DYD2_k127_6384062_2	234267.Acid_1085	7.083e-92	324.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
DYD2_k127_6384062_3	489825.LYNGBM3L_51510	2.202e-69	244.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,1H8N9@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
DYD2_k127_6403534_0	1379270.AUXF01000001_gene2822	1.687e-184	646.0	COG4797@1|root,COG4797@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
DYD2_k127_6403534_1	743299.Acife_1005	4.609e-25	121.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,1RSEU@1236|Gammaproteobacteria,2NDCA@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
DYD2_k127_6403534_2	402881.Plav_0184	0.0006581	50.0	COG0810@1|root,COG0810@2|Bacteria,1NJ1R@1224|Proteobacteria,2UGFN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
DYD2_k127_6407594_1	290397.Adeh_1133	4.025e-28	121.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
DYD2_k127_6407594_0	880073.Calab_3204	1.769e-147	491.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
DYD2_k127_6407594_2	861299.J421_2711	1.536e-25	118.0	COG0457@1|root,COG0457@2|Bacteria,1ZTX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
DYD2_k127_6427470_0	479435.Kfla_2118	1.355e-163	531.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2GMMC@201174|Actinobacteria,4DPP6@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
DYD2_k127_6427470_1	861299.J421_0308	5.005e-63	228.0	COG1595@1|root,COG1595@2|Bacteria,1ZTP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_6443749_0	1163617.SCD_n02012	4.883e-82	286.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DYD2_k127_6445587_0	391625.PPSIR1_18075	4.575e-320	997.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DYD2_k127_6445587_6	1041930.Mtc_1992	1.422e-08	67.0	arCOG07601@1|root,arCOG07601@2157|Archaea,2XY96@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
DYD2_k127_6445587_2	1382306.JNIM01000001_gene1022	1.324e-52	192.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
DYD2_k127_6445587_4	246197.MXAN_4334	3.22e-38	161.0	COG3386@1|root,COG3386@2|Bacteria,1RE3R@1224|Proteobacteria,42SFJ@68525|delta/epsilon subdivisions,2WPY7@28221|Deltaproteobacteria,2YV98@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6445587_5	1047013.AQSP01000099_gene1496	1.251e-08	64.0	COG1826@1|root,COG1826@2|Bacteria,2NQ3N@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	2.A.64,2.C.1.2	-	-	MttA_Hcf106
DYD2_k127_6445587_1	379066.GAU_0646	1.546e-78	266.0	COG1403@1|root,COG1403@2|Bacteria,1ZTF1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
DYD2_k127_6445587_3	861299.J421_2825	9.647e-42	168.0	COG1198@1|root,COG1198@2|Bacteria,1ZTE9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
DYD2_k127_6447534_0	1379270.AUXF01000003_gene3595	1.533e-84	313.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DYD2_k127_6447534_3	1379270.AUXF01000003_gene3596	1.336e-17	98.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
DYD2_k127_6447534_2	1379270.AUXF01000003_gene3597	1.644e-68	264.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993,ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	HlyD_3
DYD2_k127_6447534_1	1379270.AUXF01000002_gene1364	2.463e-75	277.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1364|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6458029_2	489825.LYNGBM3L_38110	4.427e-56	203.0	COG1216@1|root,COG1216@2|Bacteria,1GQEZ@1117|Cyanobacteria,1HI6Y@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2,Methyltransf_23
DYD2_k127_6458029_3	489825.LYNGBM3L_38090	2.635e-44	180.0	COG0726@1|root,COG0726@2|Bacteria,1G0GG@1117|Cyanobacteria	1117|Cyanobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
DYD2_k127_6458029_5	1185876.BN8_05284	4.913e-31	138.0	COG1216@1|root,COG1216@2|Bacteria,4NEJB@976|Bacteroidetes,47MPS@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
DYD2_k127_6458029_4	682795.AciX8_4887	2.14e-37	164.0	COG1287@1|root,COG1287@2|Bacteria,3Y653@57723|Acidobacteria,2JM89@204432|Acidobacteriia	204432|Acidobacteriia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6458029_1	649638.Trad_2705	2.895e-65	252.0	COG0382@1|root,COG0546@1|root,COG0382@2|Bacteria,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,UbiA
DYD2_k127_6458029_0	743299.Acife_3015	7.786e-86	299.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RMXA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fad linked oxidase	dprE1	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
DYD2_k127_646831_0	861299.J421_2988	1.323e-130	446.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_646831_2	1123508.JH636442_gene3933	2.8e-05	57.0	COG3014@1|root,COG3014@2|Bacteria,2IY9Z@203682|Planctomycetes	203682|Planctomycetes	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
DYD2_k127_6472781_0	1117943.SFHH103_02888	1.77e-92	329.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
DYD2_k127_6484055_5	1121405.dsmv_0256	1.214e-05	56.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
DYD2_k127_6484055_2	1278073.MYSTI_01802	1.688e-37	149.0	2DEWU@1|root,2ZPJP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6484055_0	991905.SL003B_3221	1.549e-51	186.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,4BQMS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
DYD2_k127_6484055_4	396588.Tgr7_2791	4.404e-07	63.0	COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,1RN4J@1236|Gammaproteobacteria,1WZ1V@135613|Chromatiales	135613|Chromatiales	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
DYD2_k127_6484055_1	391625.PPSIR1_29518	3.417e-41	166.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42S9C@68525|delta/epsilon subdivisions,2WM4G@28221|Deltaproteobacteria,2YU8Y@29|Myxococcales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	dlhH2	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
DYD2_k127_6484055_3	1223410.KN050846_gene1631	3.544e-37	143.0	COG0076@1|root,COG0076@2|Bacteria,4NGZB@976|Bacteroidetes,1HZDC@117743|Flavobacteriia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
DYD2_k127_6484907_0	448385.sce0897	4.351e-93	312.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DYD2_k127_6484907_1	300852.55772493	3.213e-87	292.0	COG0466@1|root,COG0466@2|Bacteria,1WISX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
DYD2_k127_6496565_4	861299.J421_3635	2.857e-40	163.0	COG0565@1|root,COG0565@2|Bacteria,1ZT19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	SpoU rRNA Methylase family	-	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
DYD2_k127_6496565_3	118168.MC7420_8161	1.146e-50	196.0	COG0572@1|root,COG0572@2|Bacteria,1G67K@1117|Cyanobacteria,1HC0C@1150|Oscillatoriales	1117|Cyanobacteria	F	uridine kinase	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
DYD2_k127_6496565_0	330214.NIDE1289	5.652e-247	784.0	COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae	40117|Nitrospirae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
DYD2_k127_6496565_1	1479238.JQMZ01000001_gene442	6.899e-112	376.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,43WJ0@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
DYD2_k127_6496565_2	234267.Acid_0827	1.233e-68	243.0	COG1108@1|root,COG1108@2|Bacteria,3Y93X@57723|Acidobacteria	57723|Acidobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
DYD2_k127_6496565_5	880073.Calab_1818	1.006e-27	115.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
DYD2_k127_6521658_4	269799.Gmet_2816	6.182e-14	85.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
DYD2_k127_6521658_0	1379270.AUXF01000001_gene2066	2.184e-63	247.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
DYD2_k127_6521658_2	1089550.ATTH01000001_gene731	3.15e-22	111.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
DYD2_k127_6521658_6	666685.R2APBS1_3793	4.147e-08	65.0	COG4313@1|root,COG4313@2|Bacteria,1N1DR@1224|Proteobacteria,1SGI6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
DYD2_k127_6521658_5	1485545.JQLW01000005_gene1055	7.309e-10	72.0	COG2608@1|root,COG2608@2|Bacteria,1NIWX@1224|Proteobacteria	1224|Proteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
DYD2_k127_6521658_1	1122138.AQUZ01000026_gene2978	4.938e-26	115.0	COG0789@1|root,COG0789@2|Bacteria,2IMEG@201174|Actinobacteria,4DR6J@85009|Propionibacteriales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
DYD2_k127_6521658_3	690850.Desaf_2671	1.729e-16	88.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2M8K7@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DYD2_k127_6526951_1	861299.J421_3956	4.011e-42	160.0	COG0521@1|root,COG0521@2|Bacteria,1ZU2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
DYD2_k127_6526951_0	404589.Anae109_2522	2.952e-113	377.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
DYD2_k127_6559117_1	379066.GAU_0968	1.092e-78	271.0	COG3550@1|root,COG3550@2|Bacteria	2|Bacteria	S	kinase activity	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
DYD2_k127_6559117_0	861299.J421_2617	5.358e-93	311.0	COG1092@1|root,COG1092@2|Bacteria,1ZT8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
DYD2_k127_6584395_1	1123277.KB893239_gene1231	4.451e-49	181.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
DYD2_k127_6584395_0	861299.J421_2138	1.972e-129	424.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	pucD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DYD2_k127_6590223_1	1278073.MYSTI_04223	3.844e-28	132.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WPVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
DYD2_k127_6590223_0	861299.J421_0916	4.949e-113	380.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
DYD2_k127_6597039_0	945713.IALB_0693	3.39e-117	404.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	mdtC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
DYD2_k127_6597039_1	794903.OPIT5_18660	0.0001181	52.0	COG1538@1|root,COG1538@2|Bacteria,46T0P@74201|Verrucomicrobia,3K73I@414999|Opitutae	414999|Opitutae	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
DYD2_k127_6599387_0	861299.J421_0488	5.26e-98	331.0	COG2223@1|root,COG2223@2|Bacteria,1ZT8I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
DYD2_k127_6599387_2	290397.Adeh_3495	1.088e-32	138.0	COG1937@1|root,COG1937@2|Bacteria,1NIAR@1224|Proteobacteria,42XQ4@68525|delta/epsilon subdivisions,2X31E@28221|Deltaproteobacteria,2Z282@29|Myxococcales	28221|Deltaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
DYD2_k127_6599387_1	861299.J421_1941	5.887e-67	231.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
DYD2_k127_6612178_2	1163407.UU7_05698	7.257e-141	475.0	COG1228@1|root,COG1228@2|Bacteria,1R6NP@1224|Proteobacteria,1SZBD@1236|Gammaproteobacteria,1X5QW@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
DYD2_k127_6612178_1	1121930.AQXG01000011_gene1720	2.501e-169	560.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
DYD2_k127_6612178_0	1192034.CAP_8574	4.463e-215	724.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,42Q8W@68525|delta/epsilon subdivisions,2WJVN@28221|Deltaproteobacteria,2YWG3@29|Myxococcales	28221|Deltaproteobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
DYD2_k127_661360_3	278957.ABEA03000161_gene54	5.332e-57	201.0	2EDIX@1|root,337ET@2|Bacteria,46TG5@74201|Verrucomicrobia,3K76Q@414999|Opitutae	414999|Opitutae	S	tagaturonate epimerase	-	-	-	-	-	-	-	-	-	-	-	-	UxaE
DYD2_k127_661360_5	1278073.MYSTI_04686	8.929e-44	167.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ccmA	-	3.6.3.41	ko:K01990,ko:K02193	ko02010,map02010	M00254,M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.107	-	-	ABC_tran
DYD2_k127_661360_4	1144275.COCOR_03001	3.655e-49	197.0	COG2386@1|root,COG2386@2|Bacteria,1QF23@1224|Proteobacteria,42RAM@68525|delta/epsilon subdivisions,2WMS1@28221|Deltaproteobacteria,2YVDV@29|Myxococcales	28221|Deltaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
DYD2_k127_661360_2	671143.DAMO_1590	4.391e-64	241.0	COG0755@1|root,COG0755@2|Bacteria,2NPG8@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
DYD2_k127_661360_7	1123389.ATXJ01000005_gene1869	3.189e-28	129.0	COG2332@1|root,COG2332@2|Bacteria,1WJVR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
DYD2_k127_661360_0	671143.DAMO_1588	3.666e-210	674.0	COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564	-	ko:K02198,ko:K04016	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
DYD2_k127_661360_6	928724.SacglDRAFT_02958	4.131e-36	144.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4E3DR@85010|Pseudonocardiales	201174|Actinobacteria	CO	Thiol-disulfide isomerase-like thioredoxin	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
DYD2_k127_661360_8	671143.DAMO_1586	5.84e-23	111.0	COG3088@1|root,COG3088@2|Bacteria,2NRBD@2323|unclassified Bacteria	2|Bacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02198,ko:K02200	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmH
DYD2_k127_661360_1	861299.J421_2529	9.673e-70	241.0	COG0568@1|root,COG0568@2|Bacteria,1ZSNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
DYD2_k127_6614753_0	1173025.GEI7407_1197	1.108e-280	885.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1G092@1117|Cyanobacteria,1H78E@1150|Oscillatoriales	1117|Cyanobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
DYD2_k127_6614753_2	166314.Syncc8109_2443	2.359e-27	129.0	COG0703@1|root,COG0703@2|Bacteria,1G5QW@1117|Cyanobacteria,1GYPN@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
DYD2_k127_6614753_1	1379270.AUXF01000003_gene3400	3.123e-135	443.0	COG0082@1|root,COG0082@2|Bacteria,1ZT39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
DYD2_k127_6629823_4	1125863.JAFN01000001_gene875	8.513e-12	73.0	COG0025@1|root,COG0025@2|Bacteria,1N7PG@1224|Proteobacteria,42V45@68525|delta/epsilon subdivisions,2WRJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6629823_1	1499967.BAYZ01000135_gene88	3.573e-26	112.0	COG0347@1|root,COG0347@2|Bacteria,2NRH8@2323|unclassified Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K02806,ko:K04752	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	P-II
DYD2_k127_6629823_2	1125863.JAFN01000001_gene901	2.902e-25	115.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
DYD2_k127_6629823_0	861299.J421_3183	1.854e-162	526.0	COG0766@1|root,COG0766@2|Bacteria,1ZSZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
DYD2_k127_6629823_3	1125863.JAFN01000001_gene3381	1.4e-22	115.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
DYD2_k127_6638088_0	1382304.JNIL01000001_gene1752	1.455e-140	453.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,27912@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the interconversion of ornithine to glutamate semialdehyde	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
DYD2_k127_6638088_1	1278073.MYSTI_02808	5.789e-122	398.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
DYD2_k127_667347_4	1123508.JH636440_gene2608	2.953e-30	125.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_9,Response_reg
DYD2_k127_667347_0	404589.Anae109_1755	2.761e-138	456.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,43C89@68525|delta/epsilon subdivisions,2X7IN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
DYD2_k127_667347_2	1123388.AQWU01000073_gene1106	2.494e-36	149.0	COG2120@1|root,COG2120@2|Bacteria,1WIWN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	GlcNAc-PI de-N-acetylase	lmbE	-	-	-	-	-	-	-	-	-	-	-	PIG-L
DYD2_k127_667347_7	1121385.AQXW01000004_gene1325	2.076e-27	126.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,1ZVR8@145357|Dermacoccaceae	201174|Actinobacteria	L	3' exoribonuclease, RNase T-like	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
DYD2_k127_667347_1	414684.RC1_3279	1.907e-58	228.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
DYD2_k127_667347_8	266117.Rxyl_0525	3.629e-05	57.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4CQDC@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
DYD2_k127_667347_6	1382306.JNIM01000001_gene3984	1.121e-28	130.0	COG1695@1|root,COG1695@2|Bacteria,2G974@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
DYD2_k127_667347_5	309807.SRU_1699	3.962e-30	134.0	COG0457@1|root,COG0457@2|Bacteria,4PJ45@976|Bacteroidetes,1FJJ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
DYD2_k127_667347_3	251221.35211248	2.672e-33	132.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
DYD2_k127_667968_0	1173026.Glo7428_2781	4.031e-81	303.0	COG1732@1|root,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
DYD2_k127_667968_2	306281.AJLK01000109_gene3128	2.095e-71	246.0	COG1174@1|root,COG1174@2|Bacteria,1G2ZA@1117|Cyanobacteria,1JJE8@1189|Stigonemataceae	1117|Cyanobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
DYD2_k127_667968_1	63737.Npun_F2655	5.773e-76	273.0	COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria,1HIQ3@1161|Nostocales	1117|Cyanobacteria	E	ABC-type proline glycine betaine transport	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
DYD2_k127_667968_3	266117.Rxyl_0687	6.441e-27	118.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4CPQ7@84995|Rubrobacteria	84995|Rubrobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
DYD2_k127_6683184_1	234267.Acid_2436	6.475e-09	63.0	COG3170@1|root,COG3170@2|Bacteria,3Y4RX@57723|Acidobacteria	57723|Acidobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6683184_0	330214.NIDE3591	2.128e-134	461.0	COG0744@1|root,COG0744@2|Bacteria,3J1FP@40117|Nitrospirae	40117|Nitrospirae	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
DYD2_k127_6696070_2	468059.AUHA01000004_gene2375	1.554e-57	211.0	2BXBG@1|root,33WQF@2|Bacteria,4P3CB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_6696070_0	1163409.UUA_00600	1.334e-165	557.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1X2ZJ@135614|Xanthomonadales	135614|Xanthomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
DYD2_k127_6696070_1	945713.IALB_0608	4.888e-110	376.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
DYD2_k127_6706598_0	1499967.BAYZ01000111_gene2945	2.33e-66	256.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
DYD2_k127_6706598_1	861299.J421_3637	2.367e-49	201.0	COG0747@1|root,COG0747@2|Bacteria,1ZTAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
DYD2_k127_6706598_2	379066.GAU_0729	4.89e-39	154.0	COG1704@1|root,COG1704@2|Bacteria,1ZTQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
DYD2_k127_6706598_3	382464.ABSI01000011_gene2923	2.574e-25	116.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	ant1	-	2.7.7.47	ko:K00984,ko:K19279	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2,UPF0158
DYD2_k127_6725151_3	379066.GAU_1569	5.468e-19	95.0	2EPTK@1|root,33HE4@2|Bacteria,1ZTUK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
DYD2_k127_6725151_2	1540221.JQNI01000002_gene1727	3.248e-30	128.0	COG0824@1|root,COG0824@2|Bacteria,1WKEF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
DYD2_k127_6725151_1	1121129.KB903360_gene3190	1.411e-33	141.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,2FM2C@200643|Bacteroidia,22W7E@171551|Porphyromonadaceae	976|Bacteroidetes	S	UDP-2,3-diacylglucosamine hydrolase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
DYD2_k127_6725151_0	338963.Pcar_2724	4.731e-81	285.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
DYD2_k127_675745_1	518766.Rmar_0355	2.168e-41	177.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
DYD2_k127_675745_0	589865.DaAHT2_2323	9.325e-87	297.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,42MXK@68525|delta/epsilon subdivisions,2WKEJ@28221|Deltaproteobacteria,2MI70@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
DYD2_k127_694844_0	330214.NIDE0638	1.97e-133	452.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
DYD2_k127_694844_3	1306406.ASHX01000001_gene1796	2.218e-13	83.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
DYD2_k127_694844_1	562970.Btus_0352	1.39e-29	126.0	COG4549@1|root,COG4549@2|Bacteria,1V509@1239|Firmicutes,4HH2V@91061|Bacilli,279V7@186823|Alicyclobacillaceae	91061|Bacilli	S	Domain of unkown function (DUF1775)	ycnI	-	-	-	-	-	-	-	-	-	-	-	DUF1775
DYD2_k127_694844_4	1192124.LIG30_0813	1.028e-10	68.0	2E7PS@1|root,3325B@2|Bacteria,1PVAH@1224|Proteobacteria,2VVUK@28216|Betaproteobacteria,1KAP4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_694844_5	572547.Amico_1207	0.000156	51.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Class_IIIsignal,Flp_Fap
DYD2_k127_694844_2	309807.SRU_0807	3.219e-20	101.0	2DQJQ@1|root,337AP@2|Bacteria,4PEU5@976|Bacteroidetes,1FJMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
DYD2_k127_699191_0	1379270.AUXF01000005_gene693	2.947e-100	339.0	COG0849@1|root,COG0849@2|Bacteria,1ZSRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
DYD2_k127_699191_1	379066.GAU_1439	1.094e-42	175.0	COG0206@1|root,COG0206@2|Bacteria,1ZSNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
DYD2_k127_701267_0	1121456.ATVA01000015_gene2393	1.205e-40	169.0	28I4Y@1|root,2Z88D@2|Bacteria,1R95V@1224|Proteobacteria,42RX3@68525|delta/epsilon subdivisions,2WMGE@28221|Deltaproteobacteria,2MECJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_718316_5	67352.JODS01000001_gene136	6.3e-08	60.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
DYD2_k127_718316_7	983920.Y88_0358	0.0001946	55.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2K04M@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8
DYD2_k127_718316_8	457429.ABJI02000581_gene2473	0.0009701	50.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
DYD2_k127_718316_0	861299.J421_1072	3.02e-151	486.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
DYD2_k127_718316_1	1341151.ASZU01000008_gene1348	6.775e-126	417.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,27BH0@186824|Thermoactinomycetaceae	91061|Bacilli	L	Bacterial dnaA protein helix-turn-helix domain	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
DYD2_k127_718316_4	518766.Rmar_2763	3.315e-09	61.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1FJNZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
DYD2_k127_718316_6	861299.J421_1069	6.042e-07	60.0	COG0594@1|root,COG0594@2|Bacteria,1ZV89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
DYD2_k127_718316_3	546264.NEIFLAOT_02312	6.305e-21	98.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KS03@206351|Neisseriales	206351|Neisseriales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
DYD2_k127_718316_2	1379270.AUXF01000002_gene1186	9.504e-110	377.0	COG0706@1|root,COG0706@2|Bacteria,1ZSKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
DYD2_k127_774583_4	479434.Sthe_2189	6.527e-29	122.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi,27YIE@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_774583_6	1179773.BN6_36160	0.0007342	50.0	COG5662@1|root,COG5662@2|Bacteria,2INVC@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
DYD2_k127_774583_3	1379270.AUXF01000002_gene1551	8.999e-31	142.0	COG1629@1|root,COG4771@2|Bacteria,1ZU8C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
DYD2_k127_774583_0	338966.Ppro_3581	5.94e-81	276.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,43SFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
DYD2_k127_774583_2	518766.Rmar_1377	7.947e-44	167.0	COG3019@1|root,COG3019@2|Bacteria,4P644@976|Bacteroidetes,1FJE9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
DYD2_k127_774583_5	56780.SYN_00314	7.654e-25	113.0	COG0589@1|root,COG0589@2|Bacteria,1NDJW@1224|Proteobacteria,430KQ@68525|delta/epsilon subdivisions,2WVKY@28221|Deltaproteobacteria,2MRZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_774583_1	1379270.AUXF01000002_gene1589	2.12e-46	172.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1589|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_776604_1	1379270.AUXF01000006_gene220	1.942e-109	367.0	COG2896@1|root,COG2896@2|Bacteria,1ZSMN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
DYD2_k127_776604_4	867845.KI911784_gene1283	1.386e-31	133.0	COG0314@1|root,COG0314@2|Bacteria,2G6YQ@200795|Chloroflexi,376I2@32061|Chloroflexia	32061|Chloroflexia	H	PFAM molybdopterin biosynthesis MoaE protein	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
DYD2_k127_776604_6	926566.Terro_3230	3.82e-11	71.0	COG1977@1|root,COG1977@2|Bacteria,3Y5VA@57723|Acidobacteria,2JNP3@204432|Acidobacteriia	204432|Acidobacteriia	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
DYD2_k127_776604_2	1074488.AGBX01000001_gene236	2.478e-78	277.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4FBC4@85020|Dermabacteraceae	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
DYD2_k127_776604_5	379066.GAU_1674	1.33e-26	113.0	COG0776@1|root,COG0776@2|Bacteria,1ZTTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
DYD2_k127_776604_3	1232410.KI421418_gene2310	3.98e-67	239.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,43S2J@69541|Desulfuromonadales	28221|Deltaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
DYD2_k127_776604_0	861299.J421_3306	6.47e-116	385.0	COG0505@1|root,COG0505@2|Bacteria,1ZT0T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
DYD2_k127_816582_5	871963.Desdi_1589	3.218e-18	96.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia,260WU@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
DYD2_k127_816582_0	1121428.DESHY_50081___1	2.254e-133	440.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2608E@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
DYD2_k127_816582_3	379066.GAU_0764	1.363e-41	163.0	COG0509@1|root,COG0509@2|Bacteria,1ZTWD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
DYD2_k127_816582_4	379066.GAU_1348	4.105e-35	147.0	COG4758@1|root,COG4758@2|Bacteria,1ZU48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
DYD2_k127_816582_1	1047013.AQSP01000110_gene67	1.385e-124	424.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
DYD2_k127_816582_2	1156937.MFUM_870008	3.411e-42	165.0	COG2215@1|root,COG2215@2|Bacteria,46ZB2@74201|Verrucomicrobia,37GP3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_828584_0	1267533.KB906740_gene120	2.853e-76	275.0	COG0666@1|root,COG0666@2|Bacteria,3Y6UE@57723|Acidobacteria,2JK4Y@204432|Acidobacteriia	204432|Acidobacteriia	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2
DYD2_k127_828584_2	1449049.JONW01000009_gene4446	4.794e-42	166.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2UI5V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
DYD2_k127_828584_1	404589.Anae109_2832	3.156e-52	186.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_840335_11	1123386.AUIW01000003_gene896	0.0001677	52.0	COG3437@1|root,COG3437@2|Bacteria,1WIUZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
DYD2_k127_840335_9	861299.J421_3954	5.331e-34	140.0	2C0MY@1|root,30KW5@2|Bacteria,1ZTVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_840335_10	404589.Anae109_4141	1.599e-28	132.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
DYD2_k127_840335_2	379066.GAU_0768	3.349e-77	266.0	COG1435@1|root,COG1435@2|Bacteria,1ZTB2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
DYD2_k127_840335_5	909663.KI867150_gene1538	1.618e-52	208.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42S6I@68525|delta/epsilon subdivisions,2WNNW@28221|Deltaproteobacteria,2MQGT@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K06857	ko02010,map02010	M00186,M00189	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.8	-	-	ABC_tran,TOBE
DYD2_k127_840335_6	671143.DAMO_1144	1.631e-52	196.0	COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria	2|Bacteria	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
DYD2_k127_840335_4	1382356.JQMP01000003_gene1639	2.685e-55	219.0	COG2998@1|root,COG2998@2|Bacteria,2G7MD@200795|Chloroflexi,27Z56@189775|Thermomicrobia	189775|Thermomicrobia	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
DYD2_k127_840335_3	309807.SRU_2672	4.837e-57	224.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1FIJ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
DYD2_k127_840335_1	1047013.AQSP01000052_gene2600	7.685e-86	297.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
DYD2_k127_840335_7	751994.AGIG01000028_gene1789	2.17e-40	172.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1J4ZD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355	Ubie_methyltran
DYD2_k127_840335_0	1121918.ARWE01000001_gene2336	2.669e-137	455.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43T7B@69541|Desulfuromonadales	28221|Deltaproteobacteria	EH	Anthranilate synthase component I, N terminal region	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
DYD2_k127_840335_8	379066.GAU_3908	1.739e-38	162.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
DYD2_k127_842484_5	83406.HDN1F_17130	1.934e-16	84.0	COG2402@1|root,COG2402@2|Bacteria,1NCFK@1224|Proteobacteria,1SRQ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
DYD2_k127_842484_1	1499967.BAYZ01000060_gene6005	6.045e-54	204.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
DYD2_k127_842484_6	502025.Hoch_1983	5.157e-10	63.0	2DREH@1|root,33BDY@2|Bacteria,1Q6K1@1224|Proteobacteria,433AU@68525|delta/epsilon subdivisions,2WXFM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_842484_2	502025.Hoch_1982	8.104e-52	188.0	COG1978@1|root,COG1978@2|Bacteria	2|Bacteria	S	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor	prdB	-	1.21.4.1,1.21.4.2	ko:K10672,ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
DYD2_k127_842484_3	670307.HYPDE_27273	6.425e-28	118.0	2DCBQ@1|root,32TZD@2|Bacteria,1N164@1224|Proteobacteria,2UJG3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_842484_0	452637.Oter_3293	2.387e-217	686.0	COG0281@1|root,COG0281@2|Bacteria,46UI4@74201|Verrucomicrobia,3K7KY@414999|Opitutae	414999|Opitutae	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
DYD2_k127_842484_4	926566.Terro_3558	3.658e-18	93.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria,2JIN1@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
DYD2_k127_853246_2	748247.AZKH_4186	5.818e-60	220.0	COG2199@1|root,COG3829@1|root,COG4585@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,1QWNG@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,HATPase_c,Response_reg
DYD2_k127_853246_1	309801.trd_1816	1.983e-67	246.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,27YVM@189775|Thermomicrobia	189775|Thermomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
DYD2_k127_853246_3	797209.ZOD2009_13781	1.01e-17	94.0	COG0589@1|root,arCOG02053@2157|Archaea,2XXRS@28890|Euryarchaeota,23W7D@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
DYD2_k127_853246_0	867903.ThesuDRAFT_00346	2.9e-98	352.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WCCQ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
DYD2_k127_859419_2	388413.ALPR1_00675	2.842e-78	279.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase
DYD2_k127_859419_6	1101190.ARWB01000001_gene941	6.88e-17	96.0	COG3391@1|root,COG3391@2|Bacteria,1RF7X@1224|Proteobacteria,2U7M2@28211|Alphaproteobacteria,371D9@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Lactonase, 7-bladed beta-propeller	mxaE	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,NHL
DYD2_k127_859419_0	648757.Rvan_1829	1.715e-268	854.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TU9X@28211|Alphaproteobacteria,3N6DP@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
DYD2_k127_859419_3	457398.HMPREF0326_00601	1.129e-36	148.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2WMCA@28221|Deltaproteobacteria,2MBVF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
DYD2_k127_859419_5	1216976.AX27061_0274	8.914e-28	130.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.1	-	-	SSF
DYD2_k127_859419_1	518766.Rmar_0629	4.979e-113	376.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
DYD2_k127_871955_1	1034769.KB910518_gene5084	8.829e-25	110.0	COG2318@1|root,COG2318@2|Bacteria,1VI69@1239|Firmicutes,4HPG9@91061|Bacilli,26TJI@186822|Paenibacillaceae	91061|Bacilli	S	DinB superfamily	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
DYD2_k127_871955_0	1214242.B446_20320	1.049e-47	189.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria	201174|Actinobacteria	S	Low temperature requirement	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
DYD2_k127_871955_2	1297742.A176_01748	0.0002451	48.0	2AGQS@1|root,316YI@2|Bacteria,1PY6A@1224|Proteobacteria,4354I@68525|delta/epsilon subdivisions,2WZFJ@28221|Deltaproteobacteria,2Z216@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_87226_5	1267534.KB906754_gene2679	4.872e-15	85.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria,2JIN1@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
DYD2_k127_87226_0	861299.J421_2834	3.092e-166	545.0	COG1132@1|root,COG1132@2|Bacteria,1ZT5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
DYD2_k127_87226_2	880073.Calab_2421	6.141e-69	254.0	COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria	2|Bacteria	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
DYD2_k127_87226_3	368407.Memar_2150	2.36e-67	243.0	COG1945@1|root,arCOG04490@2157|Archaea,2XX0H@28890|Euryarchaeota,2N9J2@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
DYD2_k127_87226_4	886293.Sinac_5507	7.498e-26	120.0	COG0735@1|root,COG0735@2|Bacteria,2J1A1@203682|Planctomycetes	203682|Planctomycetes	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
DYD2_k127_87226_1	861299.J421_3916	7.887e-76	267.0	COG0618@1|root,COG0618@2|Bacteria,1ZSS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
DYD2_k127_890971_8	234267.Acid_2224	2.17e-47	175.0	COG0624@1|root,COG0624@2|Bacteria,3Y7TX@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DYD2_k127_890971_0	243231.GSU2761	4.163e-228	721.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,43UDG@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM FAD dependent oxidoreductase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
DYD2_k127_890971_5	388051.AUFE01000056_gene4866	4.662e-69	262.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria,1K39I@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
DYD2_k127_890971_1	977880.RALTA_A1536	2.444e-180	594.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
DYD2_k127_890971_7	1499967.BAYZ01000090_gene4936	1.155e-54	220.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
DYD2_k127_890971_2	880073.Calab_1414	2.461e-100	335.0	COG0388@1|root,COG0388@2|Bacteria,2NPKU@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
DYD2_k127_890971_3	1299327.I546_5718	1.152e-85	309.0	COG3320@1|root,COG3320@2|Bacteria,2GKZY@201174|Actinobacteria,236ZW@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Male sterility protein	acrA1_1	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
DYD2_k127_890971_6	926560.KE387027_gene474	7.265e-58	230.0	COG0506@1|root,COG0506@2|Bacteria,1WJB7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Proline dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046983,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
DYD2_k127_890971_4	1173024.KI912154_gene887	5.473e-80	288.0	COG0624@1|root,COG0624@2|Bacteria,1G3WM@1117|Cyanobacteria	1117|Cyanobacteria	E	peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
DYD2_k127_893542_0	388413.ALPR1_00675	2.552e-181	577.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase
DYD2_k127_893542_1	379066.GAU_0147	1.079e-65	235.0	COG3391@1|root,COG3391@2|Bacteria,1ZUF6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_901977_2	479434.Sthe_3388	4.08e-90	300.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2G62W@200795|Chloroflexi,27YXY@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
DYD2_k127_901977_0	479434.Sthe_3388	0.0	1358.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2G62W@200795|Chloroflexi,27YXY@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
DYD2_k127_901977_1	479434.Sthe_3389	2.752e-134	433.0	COG0437@1|root,COG0437@2|Bacteria,2G9ZX@200795|Chloroflexi,27Y09@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S binding domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3
DYD2_k127_901977_3	479434.Sthe_3390	2.921e-87	306.0	COG3301@1|root,COG3301@2|Bacteria,2GA0G@200795|Chloroflexi,27YBQ@189775|Thermomicrobia	189775|Thermomicrobia	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
DYD2_k127_901977_4	479434.Sthe_3392	1.317e-48	190.0	COG3058@1|root,COG3058@2|Bacteria,2G9S5@200795|Chloroflexi,27YFM@189775|Thermomicrobia	189775|Thermomicrobia	O	Protein involved in formate dehydrogenase formation	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
DYD2_k127_908686_2	861299.J421_1295	1.353e-28	124.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_908686_0	266117.Rxyl_2352	2.218e-127	414.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4CRTQ@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese-like domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
DYD2_k127_908686_1	266117.Rxyl_2194	2.055e-44	170.0	COG0822@1|root,COG0822@2|Bacteria,2HNZE@201174|Actinobacteria,4CQ8X@84995|Rubrobacteria	84995|Rubrobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
DYD2_k127_939857_4	1379270.AUXF01000006_gene26	1.206e-20	101.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
DYD2_k127_939857_0	1379270.AUXF01000006_gene21	2.77e-81	308.0	COG1452@1|root,COG1452@2|Bacteria,1ZT14@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_939857_1	861299.J421_3548	4.178e-55	202.0	COG0805@1|root,COG0805@2|Bacteria,1ZTHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
DYD2_k127_939857_2	865861.AZSU01000003_gene1926	2.905e-46	172.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,36HY1@31979|Clostridiaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
DYD2_k127_939857_3	861299.J421_3549	1.071e-27	121.0	COG1729@1|root,COG1729@2|Bacteria,1ZTU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
DYD2_k127_939951_1	1356852.N008_09615	7.208e-90	311.0	COG0006@1|root,COG0006@2|Bacteria,4NI0S@976|Bacteroidetes,47MY8@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
DYD2_k127_939951_0	1121930.AQXG01000017_gene3148	1.931e-123	412.0	COG2421@1|root,COG2421@2|Bacteria,4NKD7@976|Bacteroidetes	976|Bacteroidetes	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
DYD2_k127_939951_4	575609.HMPREF0629_00214	1.723e-08	58.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia,22HZ2@1570339|Peptoniphilaceae	186801|Clostridia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
DYD2_k127_939951_2	631454.N177_2972	4.87e-50	192.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,2U5TK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
DYD2_k127_939951_3	1210908.HSB1_36690	1.425e-33	140.0	COG0300@1|root,arCOG01263@2157|Archaea,2Y7K7@28890|Euryarchaeota,23VXJ@183963|Halobacteria	183963|Halobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
DYD2_k127_941584_0	861299.J421_3848	5.232e-224	702.0	COG0443@1|root,COG0443@2|Bacteria,1ZT75@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
DYD2_k127_941584_1	861299.J421_3849	2.157e-97	344.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
DYD2_k127_947773_1	861299.J421_3044	6.311e-75	265.0	COG1624@1|root,COG1624@2|Bacteria,1ZUI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
DYD2_k127_947773_2	1380390.JIAT01000011_gene2842	1.661e-73	260.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CPWZ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
DYD2_k127_947773_0	1379270.AUXF01000005_gene656	5.098e-266	834.0	COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
DYD2_k127_947773_3	379066.GAU_1392	4.257e-67	235.0	COG0634@1|root,COG0634@2|Bacteria,1ZTH7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
DYD2_k127_947773_4	717605.Theco_3684	7.905e-21	103.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
DYD2_k127_951062_1	1382306.JNIM01000001_gene3233	4.041e-41	160.0	COG1802@1|root,COG1802@2|Bacteria,2G97X@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
DYD2_k127_951062_0	1385519.N801_15180	1.417e-152	494.0	COG2232@1|root,COG2232@2|Bacteria,2HPI0@201174|Actinobacteria,4FK2A@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
DYD2_k127_952337_3	861299.J421_3884	8.409e-20	104.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
DYD2_k127_952337_0	1463887.KL590004_gene1996	2.811e-65	231.0	COG3217@1|root,COG3217@2|Bacteria	2|Bacteria	S	molybdenum ion binding	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
DYD2_k127_952337_4	391937.NA2_15107	1.196e-17	94.0	COG3794@1|root,COG3794@2|Bacteria,1PM8W@1224|Proteobacteria,2UZW8@28211|Alphaproteobacteria,43QJI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
DYD2_k127_952337_2	391937.NA2_15112	5.996e-50	184.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2TUSW@28211|Alphaproteobacteria,43KTZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4142)	MA20_42090	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
DYD2_k127_952337_1	1122939.ATUD01000015_gene1010	6.666e-54	203.0	COG1595@1|root,COG1595@2|Bacteria,2IG3F@201174|Actinobacteria,4CT96@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
DYD2_k127_959633_1	1267005.KB911256_gene2174	7.655e-08	65.0	2AEH0@1|root,314C7@2|Bacteria,1PTWQ@1224|Proteobacteria,2VBU8@28211|Alphaproteobacteria,3N9BT@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
DYD2_k127_959633_0	935567.JAES01000024_gene1427	4.804e-108	364.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria,1X5T4@135614|Xanthomonadales	135614|Xanthomonadales	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
DYD2_k127_968010_1	1081644.IMCC13023_12230	1.314e-29	134.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4FMKM@85023|Microbacteriaceae	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
DYD2_k127_968010_0	29581.BW37_03022	1.103e-198	660.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria	1224|Proteobacteria	E	oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
DYD2_k127_968010_2	479434.Sthe_0269	3.571e-17	89.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
DYD2_k127_974739_3	861299.J421_3745	1.222e-52	203.0	COG0760@1|root,COG0760@2|Bacteria,1ZSU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
DYD2_k127_974739_1	861299.J421_3744	3.57e-76	284.0	COG1995@1|root,COG1995@2|Bacteria,1ZT2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
DYD2_k127_974739_0	379066.GAU_2160	1.084e-79	278.0	COG2884@1|root,COG2884@2|Bacteria,1ZTHQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
DYD2_k127_974739_2	861299.J421_3760	3.483e-55	211.0	COG2177@1|root,COG2177@2|Bacteria,1ZTDR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Part of the ABC transporter FtsEX involved in	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
DYD2_k127_974739_4	1379270.AUXF01000003_gene3684	8e-46	188.0	COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
DYD2_k127_988915_1	926554.KI912647_gene1816	1.189e-10	73.0	COG3427@1|root,COG3427@2|Bacteria,1WMX6@1297|Deinococcus-Thermus	2|Bacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
DYD2_k127_988915_0	196490.AUEZ01000042_gene7227	8.348e-233	730.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
DYD2_k127_993783_2	1030157.AFMP01000016_gene2448	1.169e-12	75.0	COG2244@1|root,COG2244@2|Bacteria,1PDRG@1224|Proteobacteria,2TVKM@28211|Alphaproteobacteria,2K0P5@204457|Sphingomonadales	204457|Sphingomonadales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
DYD2_k127_993783_0	1089553.Tph_c20790	2.478e-70	258.0	COG0558@1|root,COG1213@1|root,COG0558@2|Bacteria,COG1213@2|Bacteria,1V33I@1239|Firmicutes	1239|Firmicutes	IM	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.7.74,2.7.8.34	ko:K07281,ko:K07291	ko00562,map00562	-	R09669,R09670	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,NTP_transf_3
DYD2_k127_993783_1	748247.AZKH_0408	1.719e-23	116.0	COG2199@1|root,COG5000@1|root,COG3706@2|Bacteria,COG5000@2|Bacteria,1MZV7@1224|Proteobacteria,2WEG8@28216|Betaproteobacteria,2M03X@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
## 2006 queries scanned
## Total time (seconds): 4.766669034957886
## Rate: 420.84 q/s