## Mon Mar 17 03:45:59 2025 ## emapper-2.1.9 ## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/DYD3_bin.66.fa -m mmseqs --itype genome -o DYD3_bin.66 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/DYD3_bin.66 --cpu 8 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs DYD3_k127_1000910_7 1463936.JOJI01000003_gene914 3.66e-07 63.0 COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria 201174|Actinobacteria Q amidohydrolase - - - - - - - - - - - - Amidohydro_1 DYD3_k127_1000910_4 1185876.BN8_01704 1.776e-38 165.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia 976|Bacteroidetes QU Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,PD40 DYD3_k127_1000910_3 1218084.BBJK01000176_gene7931 3.373e-44 170.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2VIXW@28216|Betaproteobacteria,1JZMU@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - Hemerythrin,PNP_phzG_C,Putative_PNPOx DYD3_k127_1000910_0 1129374.AJE_17410 4.464e-201 630.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,4644Q@72275|Alteromonadaceae 1236|Gammaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N DYD3_k127_1000910_5 502025.Hoch_6599 2.47e-34 138.0 COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales 28221|Deltaproteobacteria E Prephenate dehydrogenase chorismate mutase - - 1.3.1.12 ko:K00210 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - CM_2,PDH DYD3_k127_1000910_1 502025.Hoch_6599 8.205e-79 268.0 COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales 28221|Deltaproteobacteria E Prephenate dehydrogenase chorismate mutase - - 1.3.1.12 ko:K00210 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - CM_2,PDH DYD3_k127_1000910_2 1049564.TevJSym_ao00490 9.386e-60 218.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1SZ82@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Protein of unknown function, DUF484 - - - - - - - - - - - - DUF484,GGDEF DYD3_k127_1003487_2 861299.J421_0330 3.676e-90 305.0 COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 DYD3_k127_1003487_0 314287.GB2207_07073 8.807e-301 940.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1J4Q5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C malic enzyme maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic DYD3_k127_1003487_1 234267.Acid_3236 1.599e-159 525.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria 2|Bacteria G Dehydrogenase - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD3_k127_1003487_4 349163.Acry_1739 1.227e-11 70.0 COG2010@1|root,COG2010@2|Bacteria,1NBIA@1224|Proteobacteria,2UHSH@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 DYD3_k127_1003487_3 234267.Acid_3236 6.119e-45 172.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria 2|Bacteria G Dehydrogenase - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD3_k127_1003956_0 765910.MARPU_00485 2.766e-220 694.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1WWEX@135613|Chromatiales 135613|Chromatiales S PFAM ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn DYD3_k127_1003956_1 1121374.KB891576_gene514 6.976e-06 50.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 DYD3_k127_1004456_0 1250232.JQNJ01000001_gene1661 2.187e-122 404.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD3_k127_1004456_1 204773.HEAR1102 1.04e-118 392.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,472P9@75682|Oxalobacteraceae 28216|Betaproteobacteria M Glycosyltransferase gtrA - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 DYD3_k127_1004456_2 1122951.ATUE01000008_gene34 6.551e-28 117.0 COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,3NT69@468|Moraxellaceae 1236|Gammaproteobacteria I Acid phosphatase homologues - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 DYD3_k127_1004568_0 395019.Bmul_0859 8.864e-137 444.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,1K0I7@119060|Burkholderiaceae 28216|Betaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA DYD3_k127_1004568_1 1283300.ATXB01000001_gene799 4.035e-33 132.0 COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria,1XDV2@135618|Methylococcales 135618|Methylococcales F Belongs to the dCTP deaminase family dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase DYD3_k127_1006412_0 713586.KB900536_gene2234 0.0 1024.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales 135613|Chromatiales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom DYD3_k127_1006412_2 765910.MARPU_04230 2.485e-44 167.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1WY2S@135613|Chromatiales 135613|Chromatiales J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC DYD3_k127_1006412_1 1121878.AUGL01000025_gene1840 8.997e-143 464.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760 Coprogen_oxidas DYD3_k127_10078_3 1122134.KB893650_gene34 2.419e-92 310.0 COG0654@1|root,COG0654@2|Bacteria,1R7UC@1224|Proteobacteria,1S1B9@1236|Gammaproteobacteria,1XQV5@135619|Oceanospirillales 135619|Oceanospirillales CH FAD binding domain - - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD3_k127_10078_5 697282.Mettu_1997 2.407e-49 180.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,1XF82@135618|Methylococcales 135618|Methylococcales H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis - - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 DYD3_k127_10078_1 264198.Reut_A0915 1.446e-138 444.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,1K0Y1@119060|Burkholderiaceae 28216|Betaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt DYD3_k127_10078_2 187272.Mlg_0592 8.669e-105 347.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1WW3W@135613|Chromatiales 135613|Chromatiales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT DYD3_k127_10078_0 713586.KB900536_gene2613 9.052e-252 794.0 COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales 135613|Chromatiales O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - Thioredox_DsbH DYD3_k127_10078_4 1232410.KI421413_gene569 4.535e-58 214.0 COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,42SMK@68525|delta/epsilon subdivisions,2WSC2@28221|Deltaproteobacteria,43TI9@69541|Desulfuromonadales 28221|Deltaproteobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 DYD3_k127_10078_6 1535422.ND16A_1280 6.466e-07 52.0 COG0265@1|root,COG0265@2|Bacteria,1RBDX@1224|Proteobacteria 1224|Proteobacteria O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 DYD3_k127_1013715_2 331869.BAL199_20949 2.49e-36 147.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,4BSDR@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S COG0790 FOG TPR repeat, SEL1 subfamily - - - ko:K07126 - - - - ko00000 - - - Sel1 DYD3_k127_1013715_1 1156937.MFUM_880007 3.2e-143 464.0 COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,46SGF@74201|Verrucomicrobia,37G6C@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia HP ThiF family thiF - 2.7.7.80,2.8.1.11 ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF DYD3_k127_1013715_0 639030.JHVA01000001_gene1853 9.565e-200 628.0 COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia 204432|Acidobacteriia S cellulose binding - - - - - - - - - - - - BNR DYD3_k127_1013715_4 1089544.KB912942_gene1353 2.837e-30 125.0 COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria 201174|Actinobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - - - - - - - - - - ThiS DYD3_k127_1013715_3 748247.AZKH_2953 1.346e-30 127.0 COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,2KX2B@206389|Rhodocyclales 206389|Rhodocyclales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD3_k127_1026064_1 1333523.L593_00745 5.476e-11 74.0 COG0642@1|root,arCOG02327@2157|Archaea,2XTH8@28890|Euryarchaeota,23S6Q@183963|Halobacteria 183963|Halobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_8 DYD3_k127_1026064_0 595537.Varpa_1070 1.502e-28 120.0 COG2334@1|root,COG2334@2|Bacteria,1MXTW@1224|Proteobacteria,2VUCA@28216|Betaproteobacteria 28216|Betaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH DYD3_k127_1038813_1 203122.Sde_3064 1.059e-33 136.0 COG3548@1|root,COG3548@2|Bacteria,1RE3H@1224|Proteobacteria,1S58N@1236|Gammaproteobacteria,46B63@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 DYD3_k127_1038813_0 1122134.KB893650_gene472 9.561e-97 340.0 COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,1XRZ9@135619|Oceanospirillales 135619|Oceanospirillales H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarboxypepD_reg,Plug,TonB_dep_Rec DYD3_k127_1045359_0 936455.KI421499_gene3747 2.639e-192 606.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,3JW5G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD3_k127_1045359_1 266264.Rmet_3671 1.025e-85 295.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria 28216|Betaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC DYD3_k127_1045359_2 1172186.KB911467_gene1860 6.193e-15 77.0 COG0154@1|root,COG0154@2|Bacteria,2I9DH@201174|Actinobacteria,23EW2@1762|Mycobacteriaceae 201174|Actinobacteria J Amidase - - - - - - - - - - - - Amidase DYD3_k127_10500_2 1123073.KB899242_gene1407 7.319e-28 115.0 COG4496@1|root,COG4496@2|Bacteria,1NAAX@1224|Proteobacteria,1SG3S@1236|Gammaproteobacteria,1X7DY@135614|Xanthomonadales 135614|Xanthomonadales S protein, YerC YecD - - - - - - - - - - - - Trp_repressor DYD3_k127_10500_0 1121878.AUGL01000001_gene239 4.965e-155 503.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3939,iBWG_1329.BWG_3608,iECDH10B_1368.ECDH10B_4128,iECDH1ME8569_1439.ECDH1ME8569_3808,iETEC_1333.ETEC_4208,iEcDH1_1363.EcDH1_4046,iEcHS_1320.EcHS_A4172,iEcolC_1368.EcolC_4076,iJO1366.b3939,iJR904.b3939,iUMNK88_1353.UMNK88_4777,iUTI89_1310.UTI89_C4524,iY75_1357.Y75_RS17365 Cys_Met_Meta_PP DYD3_k127_10500_1 331678.Cphamn1_0820 4.522e-129 421.0 COG2021@1|root,COG2021@2|Bacteria,1FDS7@1090|Chlorobi 1090|Chlorobi E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metXA - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD3_k127_10500_3 84531.JMTZ01000006_gene3502 4.933e-13 70.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1X4UN@135614|Xanthomonadales 135614|Xanthomonadales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD3_k127_1052470_1 713586.KB900536_gene521 2.127e-79 280.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1WWVE@135613|Chromatiales 135613|Chromatiales M PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C - - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 DYD3_k127_1052470_0 261292.Nit79A3_0718 2.898e-129 434.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2WGNM@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator - - - ko:K06714,ko:K07713 ko02020,map02020 M00499 - - ko00000,ko00001,ko00002,ko02022,ko03000 - - - HTH_8,PAS_4,Sigma54_activat DYD3_k127_1052470_3 1283300.ATXB01000002_gene3058 2.489e-15 79.0 COG0861@1|root,COG0861@2|Bacteria 2|Bacteria P Integral membrane protein TerC family - - - - - - - - - - - - PGPGW DYD3_k127_1052470_2 118161.KB235922_gene986 2.601e-60 213.0 COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,3VHRB@52604|Pleurocapsales 1117|Cyanobacteria Q Phospholipase/Carboxylesterase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD3_k127_1052807_3 314285.KT71_12795 1.015e-41 162.0 COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1J8ZH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD3_k127_1052807_1 1453501.JELR01000005_gene1677 7.137e-109 369.0 COG2010@1|root,COG2133@1|root,COG2730@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2730@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,465UX@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - CBM_2,Cytochrome_CBB3,GSDH,PSCyt3,PSD3,PSD4,PSD5,SGL DYD3_k127_1052807_0 1278073.MYSTI_00409 2.354e-113 373.0 2C1VH@1|root,2Z7Z3@2|Bacteria,1MY5B@1224|Proteobacteria 1224|Proteobacteria S 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase wbxY - - - - - - - - - - - Kdo_hydroxy DYD3_k127_1052807_2 1049564.TevJSym_ac00330 7.124e-78 271.0 2CGG3@1|root,33XQ6@2|Bacteria,1NWYE@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_1066173_1 105559.Nwat_1241 1.021e-65 230.0 COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1X0P1@135613|Chromatiales 135613|Chromatiales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N DYD3_k127_1066173_0 287.DR97_1703 7.546e-96 323.0 COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1YEWU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0109 QRPTase_C,QRPTase_N DYD3_k127_1066173_2 105559.Nwat_2894 1.068e-50 182.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg DYD3_k127_1105366_3 1123514.KB905899_gene785 3.927e-36 141.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales 72273|Thiotrichales O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N DYD3_k127_1105366_2 1469245.JFBG01000061_gene2311 5.625e-83 291.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1WW0U@135613|Chromatiales 135613|Chromatiales O HflC and HflK could regulate a protease - - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 DYD3_k127_1105366_4 1323663.AROI01000004_gene2097 1.906e-10 64.0 COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,1SH40@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yjeT - - ko:K09937 - - - - ko00000 - - - DUF2065 DYD3_k127_1105366_0 391615.ABSJ01000055_gene1354 2.552e-205 647.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1J4X6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889 Adenylsucc_synt DYD3_k127_1105366_1 318161.Sden_0007 2.399e-117 398.0 COG5276@1|root,COG5276@2|Bacteria,1R5D5@1224|Proteobacteria,1RMBK@1236|Gammaproteobacteria,2QDPA@267890|Shewanellaceae 1236|Gammaproteobacteria M Calx-beta domain - - - - - - - - - - - - Calx-beta,LVIVD,P_proprotein DYD3_k127_1108314_2 1121940.AUDZ01000007_gene2264 1.261e-24 111.0 COG3195@1|root,COG3195@2|Bacteria,1RH9S@1224|Proteobacteria,1S25P@1236|Gammaproteobacteria,1XKCJ@135619|Oceanospirillales 135619|Oceanospirillales S OHCU decarboxylase - - - - - - - - - - - - OHCU_decarbox DYD3_k127_1108314_0 1121033.AUCF01000008_gene5710 3.215e-158 503.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,2JQCA@204441|Rhodospirillales 204441|Rhodospirillales G Polysaccharide deacetylase - - 3.5.1.41 ko:K01452 ko00520,ko01100,map00520,map01100 - R02333 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Polysacc_deac_1 DYD3_k127_1108314_1 1121923.GPUN_0387 3.068e-55 198.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,46A4Z@72275|Alteromonadaceae 1236|Gammaproteobacteria S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N DYD3_k127_1112984_1 1129794.C427_0994 4.429e-25 114.0 2C3X5@1|root,32RCX@2|Bacteria,1RKW4@1224|Proteobacteria,1S73W@1236|Gammaproteobacteria,467FK@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_1112984_0 1121940.AUDZ01000017_gene2451 1.208e-54 204.0 COG0697@1|root,COG0697@2|Bacteria,1MXPW@1224|Proteobacteria,1S8DG@1236|Gammaproteobacteria,1XM1W@135619|Oceanospirillales 135619|Oceanospirillales EG S-adenosylmethionine uptake transporter - - - - - - - - - - - - EamA DYD3_k127_1112984_2 1123248.KB893315_gene3135 9.679e-09 57.0 COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1IR7E@117747|Sphingobacteriia 976|Bacteroidetes S Transferrin receptor-like dimerisation domain - - 3.4.17.21 ko:K01301 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28,TFR_dimer DYD3_k127_1126693_0 765912.Thimo_2365 1.419e-298 929.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales 135613|Chromatiales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF DYD3_k127_1129092_3 1122962.AULH01000001_gene1548 4.623e-30 123.0 COG0662@1|root,COG0662@2|Bacteria,1N00P@1224|Proteobacteria,2UEIF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 DYD3_k127_1129092_1 1231190.NA8A_16171 4.681e-68 241.0 COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TRFW@28211|Alphaproteobacteria,43I3E@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ with different specificities (related to short-chain alcohol ygfF - - - - - - - - - - - adh_short_C2 DYD3_k127_1129092_0 675812.VHA_001840 7.176e-93 312.0 COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,1XUQM@135623|Vibrionales 135623|Vibrionales F phosphorylase deoD GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0034641,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:1901360 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 DYD3_k127_1129092_2 755732.Fluta_1925 1.937e-64 226.0 COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,1ICQK@117743|Flavobacteriia,2PBS2@246874|Cryomorphaceae 976|Bacteroidetes F DeoC/LacD family aldolase deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC DYD3_k127_1130235_1 105559.Nwat_3139 1.786e-47 177.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1WXDT@135613|Chromatiales 135613|Chromatiales J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB DYD3_k127_1130235_0 1260251.SPISAL_00395 1.15e-120 392.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1WWIP@135613|Chromatiales 135613|Chromatiales S 2-methylcitrate dehydratase prpD - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD DYD3_k127_1173199_1 1286093.C266_22715 3.624e-60 214.0 COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,1K174@119060|Burkholderiaceae 28216|Betaproteobacteria L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N DYD3_k127_1173199_2 305900.GV64_05585 3.289e-58 206.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1XJKE@135619|Oceanospirillales 135619|Oceanospirillales K Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR DYD3_k127_1173199_4 1502852.FG94_03145 4.952e-18 88.0 COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,474IE@75682|Oxalobacteraceae 28216|Betaproteobacteria J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamE - - ko:K06186 - - - - ko00000,ko02000 1.B.33.1 - - SmpA_OmlA DYD3_k127_1173199_5 493475.GARC_2671 2.497e-17 86.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,1SCHG@1236|Gammaproteobacteria,467WA@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0125 (RnfH) family rnfH - - ko:K09801 - - - - ko00000 - - - Ub-RnfH DYD3_k127_1173199_3 870187.Thini_4089 6.265e-39 154.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,4611H@72273|Thiotrichales 72273|Thiotrichales I Polyketide cyclase dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc DYD3_k127_1173199_0 472759.Nhal_0886 1.085e-89 302.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1WWZ8@135613|Chromatiales 135613|Chromatiales S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD3_k127_117909_3 187272.Mlg_1851 2.03e-84 288.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales 135613|Chromatiales M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB DYD3_k127_117909_2 497321.C664_00280 8.061e-97 323.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KV6X@206389|Rhodocyclales 206389|Rhodocyclales M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep DYD3_k127_117909_4 1249634.D781_3517 1.132e-50 183.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,401QP@613|Serratia 1236|Gammaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - iJN746.PP_1602 FabA DYD3_k127_117909_1 1163407.UU7_00812 1.169e-99 335.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1X2Y9@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD DYD3_k127_117909_5 1283300.ATXB01000001_gene1314 2.412e-31 131.0 COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,1XF7V@135618|Methylococcales 135618|Methylococcales M Belongs to the skp family - - - ko:K06142 - - - - ko00000 - - - OmpH DYD3_k127_117909_0 519989.ECTPHS_08493 5.946e-151 497.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1WXD9@135613|Chromatiales 135613|Chromatiales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA DYD3_k127_1185582_0 395493.BegalDRAFT_0638 0.0 1212.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales 72273|Thiotrichales E Vitamin B12 dependent methionine synthase, activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans DYD3_k127_1185582_1 224911.27354020 1.035e-71 249.0 COG0824@1|root,COG0824@2|Bacteria,1R6A6@1224|Proteobacteria,2TU6J@28211|Alphaproteobacteria,3JR33@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Thioesterase - - - - - - - - - - - - - DYD3_k127_1199058_0 1144275.COCOR_06708 4.316e-72 252.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,42SUN@68525|delta/epsilon subdivisions,2WPCU@28221|Deltaproteobacteria,2YXKB@29|Myxococcales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD3_k127_1199058_1 396588.Tgr7_0189 1.784e-68 241.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria 1236|Gammaproteobacteria D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA DYD3_k127_1222501_3 1056820.KB900641_gene454 5.57e-08 56.0 COG1396@1|root,COG1396@2|Bacteria,1R3Z8@1224|Proteobacteria,1RRMV@1236|Gammaproteobacteria,2PPU3@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria K Protein of unknown function (DUF3612) - - - - - - - - - - - - DUF3612,HTH_19,HTH_3,Peptidase_M78 DYD3_k127_1222501_0 1453501.JELR01000002_gene1323 7.348e-56 208.0 COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,1S133@1236|Gammaproteobacteria,466F5@72275|Alteromonadaceae 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - DYD3_k127_1222501_1 1049564.TevJSym_au00060 1.445e-44 167.0 COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,1S3TB@1236|Gammaproteobacteria,1JAUR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD DYD3_k127_1222501_2 1049564.TevJSym_au00050 1.144e-33 134.0 COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,1JAY5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD DYD3_k127_1225698_2 1248916.ANFY01000003_gene509 2.317e-12 70.0 COG2041@1|root,COG2041@2|Bacteria,1NCVN@1224|Proteobacteria,2UGB2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - - - - - - - - - - Oxidored_molyb DYD3_k127_1225698_1 172088.AUGA01000005_gene7832 1.419e-52 190.0 COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,2U8HG@28211|Alphaproteobacteria,3K0NF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DinB family dinB - - - - - - - - - - - DinB DYD3_k127_1225698_0 1242864.D187_000932 6.193e-86 306.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria 1224|Proteobacteria G Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 DYD3_k127_1233114_3 1437882.AZRU01000099_gene1115 9.17e-05 51.0 COG0589@1|root,COG0589@2|Bacteria,1QEYF@1224|Proteobacteria,1TBX9@1236|Gammaproteobacteria,1YJFR@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Universal stress protein family - - - - - - - - - - - - Usp DYD3_k127_1233114_0 314285.KT71_13030 1.668e-202 642.0 COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,1RY1C@1236|Gammaproteobacteria,1J7RH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD3_k127_1233114_1 765911.Thivi_3843 9.013e-24 108.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD3_k127_1233114_2 580332.Slit_2142 3.852e-18 86.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,44VAB@713636|Nitrosomonadales 28216|Betaproteobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N DYD3_k127_1235863_0 105559.Nwat_2894 5.625e-152 507.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg DYD3_k127_1238829_3 935840.JAEQ01000003_gene279 2.003e-76 260.0 COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Aminomethyltransferase folate-binding domain - - 2.1.1.341 ko:K15066 ko00627,ko01120,map00627,map01120 - R09271,R10136 RC00113,RC00392 ko00000,ko00001,ko01000 - - - GCV_T,GCV_T_C DYD3_k127_1238829_0 882083.SacmaDRAFT_3158 2.962e-273 857.0 COG3848@1|root,COG3848@2|Bacteria,2I3FP@201174|Actinobacteria,4EAD5@85010|Pseudonocardiales 201174|Actinobacteria T PEP-utilising enzyme, mobile domain - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers DYD3_k127_1238829_2 627192.SLG_06530 2.546e-101 344.0 COG0574@1|root,COG0574@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N DYD3_k127_1238829_4 76114.ebB9 1.069e-29 129.0 COG0511@1|root,COG0511@2|Bacteria,1N4VN@1224|Proteobacteria,2W4GP@28216|Betaproteobacteria 28216|Betaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-coa - - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl DYD3_k127_1238829_1 76114.ebA314 2.981e-187 595.0 COG5016@1|root,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VK1R@28216|Betaproteobacteria 28216|Betaproteobacteria C Conserved carboxylase domain - - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - HMGL-like,PYC_OADA DYD3_k127_1241799_2 1123242.JH636434_gene3744 5.97e-164 535.0 COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes 203682|Planctomycetes Q PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_3 DYD3_k127_1241799_3 1123073.KB899241_gene3507 3.749e-72 257.0 COG1524@1|root,COG1524@2|Bacteria,1PR75@1224|Proteobacteria,1RZUP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest DYD3_k127_1241799_1 247634.GPB2148_1836 2.075e-167 535.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1J7U8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG0665 Glycine D-amino acid oxidases (deaminating) ordL GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO DYD3_k127_1241799_0 1123053.AUDG01000004_gene3391 2.093e-176 557.0 COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RRMI@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase DYD3_k127_1269343_4 1145276.T479_00355 1.68e-09 59.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3IX7H@400634|Lysinibacillus 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro DYD3_k127_1269343_1 1121422.AUMW01000012_gene2929 6.773e-167 536.0 COG0833@1|root,COG0833@2|Bacteria,1UHPU@1239|Firmicutes,25E64@186801|Clostridia 186801|Clostridia E Amino acid permease - - - - - - - - - - - - AA_permease_2 DYD3_k127_1269343_2 313606.M23134_05036 4.951e-104 363.0 COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47NEB@768503|Cytophagia 976|Bacteroidetes P Na+/Pi-cotransporter - - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans DYD3_k127_1269343_3 713586.KB900536_gene2991 9.824e-25 113.0 COG3945@1|root,COG3945@2|Bacteria,1NDGV@1224|Proteobacteria,1SGA3@1236|Gammaproteobacteria,1X27K@135613|Chromatiales 135613|Chromatiales S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin DYD3_k127_1269343_0 291985.CCSI01000004_gene719 4.645e-251 788.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2K9UC@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD3_k127_1269343_5 1120983.KB894571_gene2622 2.196e-05 47.0 2C91B@1|root,33D4Z@2|Bacteria,1N875@1224|Proteobacteria,2UFUE@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_1269649_0 1415779.JOMH01000001_gene332 7.736e-122 410.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1X48I@135614|Xanthomonadales 135614|Xanthomonadales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 DYD3_k127_127439_0 243233.MCA0383 7.551e-150 486.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XDTZ@135618|Methylococcales 135618|Methylococcales S modulator of DNA gyrase pmbA - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD DYD3_k127_127439_4 396588.Tgr7_2265 3.901e-21 99.0 COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria 1224|Proteobacteria S Belongs to the UPF0307 family yjgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09889 - - - - ko00000,ko03009 - - - DUF615 DYD3_k127_127439_3 666685.R2APBS1_2934 2.651e-65 231.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1X58Z@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC DYD3_k127_127439_1 869210.Marky_1688 1.522e-105 353.0 COG0026@1|root,COG0026@2|Bacteria,1WITC@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp DYD3_k127_127439_2 396588.Tgr7_2396 3.01e-88 307.0 COG1716@1|root,COG3267@1|root,COG1716@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1WWX7@135613|Chromatiales 135613|Chromatiales U Type II secretory pathway component ExeA - - - ko:K02450,ko:K12283 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22 DYD3_k127_1315280_2 396588.Tgr7_2953 1.191e-123 411.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales 135613|Chromatiales O Belongs to the peptidase S1C family - - 3.4.21.107 ko:K04771,ko:K04772 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 DYD3_k127_1315280_5 519989.ECTPHS_09393 3.043e-42 162.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales 135613|Chromatiales O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 DYD3_k127_1315280_0 1234364.AMSF01000090_gene2456 0.0 1129.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN DYD3_k127_1315280_3 314287.GB2207_04129 3.78e-87 296.0 COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria,1J553@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F COG0209 Ribonucleotide reductase, alpha subunit nrdJb - - - - - - - - - - - - DYD3_k127_1315280_1 1049564.TevJSym_bt00170 1.505e-126 418.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1J4EF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1519 3-deoxy-D-manno-octulosonic-acid transferase waaA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417 Glycos_transf_1,Glycos_transf_N DYD3_k127_1315280_4 396588.Tgr7_0483 8.466e-84 292.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1WVXZ@135613|Chromatiales 135613|Chromatiales MU type I secretion outer membrane protein, TolC - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP DYD3_k127_1320995_1 1121943.KB900003_gene2816 4.232e-112 370.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1XHHX@135619|Oceanospirillales 135619|Oceanospirillales J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD3_k127_1320995_2 349124.Hhal_2234 1.197e-76 267.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,1WX0I@135613|Chromatiales 135613|Chromatiales S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 DYD3_k127_1320995_0 396588.Tgr7_0817 0.0 1372.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales 135613|Chromatiales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD3_k127_1320995_4 765911.Thivi_0489 2.527e-25 111.0 COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1WYXS@135613|Chromatiales 135613|Chromatiales S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 DYD3_k127_1320995_3 1123518.ARWI01000001_gene2431 3.313e-29 121.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,461RE@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 DYD3_k127_1332705_0 1134474.O59_002328 6.866e-116 380.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,1FG0P@10|Cellvibrio 1236|Gammaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans DYD3_k127_1332705_2 1123368.AUIS01000006_gene584 1.601e-29 123.0 COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,1S970@1236|Gammaproteobacteria,2NCZI@225057|Acidithiobacillales 225057|Acidithiobacillales F Belongs to the Nudix hydrolase family. NudJ subfamily nudJ - - - - - - - - - - - NUDIX DYD3_k127_1332705_3 314278.NB231_06990 2.115e-22 103.0 COG2153@1|root,COG2153@2|Bacteria,1N7TN@1224|Proteobacteria,1SCI6@1236|Gammaproteobacteria,1WYQK@135613|Chromatiales 135613|Chromatiales S protein acetylation - - - - - - - - - - - - - DYD3_k127_1332705_1 396588.Tgr7_1850 9.162e-57 211.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,1WYFQ@135613|Chromatiales 135613|Chromatiales S A domain family that is part of the cupin metalloenzyme superfamily. - - 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 DYD3_k127_1340229_1 1144319.PMI16_01530 2.145e-44 163.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,472M3@75682|Oxalobacteraceae 28216|Betaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD3_k127_1340229_0 1122194.AUHU01000004_gene1349 9.632e-87 297.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,465Y3@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 DYD3_k127_1346467_1 204669.Acid345_1900 1.962e-53 197.0 COG2936@1|root,COG2936@2|Bacteria,3Y6W3@57723|Acidobacteria 57723|Acidobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD3_k127_1346467_0 177437.HRM2_10590 2.19e-110 366.0 COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria 1224|Proteobacteria O cysteine protease - - - - - - - - - - - - DUF900,Peptidase_C1 DYD3_k127_1419296_3 1037409.BJ6T_24690 3.27e-35 136.0 COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2TWPT@28211|Alphaproteobacteria,3JVV3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrome_CBB3 DYD3_k127_1419296_1 941449.dsx2_3132 4.989e-127 415.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2M9BS@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM Molybdopterin dehydrogenase, FAD-binding - - 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD3_k127_1419296_0 644968.DFW101_0023 8.178e-218 701.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MAGR@213115|Desulfovibrionales 28221|Deltaproteobacteria C xanthine dehydrogenase a b hammerhead - - 1.17.1.4 ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2 DYD3_k127_1419296_2 941449.dsx2_3134 1.908e-64 227.0 COG2080@1|root,COG2080@2|Bacteria,1N1KQ@1224|Proteobacteria,42UD3@68525|delta/epsilon subdivisions,2WPH9@28221|Deltaproteobacteria,2M9N0@213115|Desulfovibrionales 28221|Deltaproteobacteria C 2Fe-2S -binding - - - - - - - - - - - - Fer2,Fer2_2 DYD3_k127_1427213_1 1408418.JNJH01000074_gene159 1.047e-31 132.0 COG0642@1|root,COG1352@1|root,COG2201@1|root,COG4566@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,COG4566@2|Bacteria,1NRP8@1224|Proteobacteria,2TWP9@28211|Alphaproteobacteria,2JYV4@204441|Rhodospirillales 204441|Rhodospirillales T Protein-glutamate methylesterase - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,GerE,HATPase_c,HisKA,PAS_10,Response_reg DYD3_k127_1427213_2 1121943.KB899995_gene874 3.293e-27 120.0 COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,1S70H@1236|Gammaproteobacteria,1XKFQ@135619|Oceanospirillales 135619|Oceanospirillales S Invasion gene expression up-regulator - - - - - - - - - - - - SirB DYD3_k127_1427213_0 84531.JMTZ01000056_gene2566 5.242e-68 249.0 COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1X35F@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,TonB_dep_Rec DYD3_k127_1432050_0 377629.TERTU_0102 1.039e-240 760.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,1RPMX@1236|Gammaproteobacteria,2PPGS@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria E Oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N DYD3_k127_1432050_2 566466.NOR53_1260 3.308e-19 96.0 2CKE6@1|root,32ZEV@2|Bacteria,1NBRM@1224|Proteobacteria,1SCY3@1236|Gammaproteobacteria,1J78W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Family of unknown function (DUF5329) - - - - - - - - - - - - DUF5329 DYD3_k127_1432050_1 105559.Nwat_2707 1.344e-85 294.0 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WZYU@135613|Chromatiales 135613|Chromatiales S peptidase M48, Ste24p - - - - - - - - - - - - Peptidase_M48,TPR_16 DYD3_k127_1456559_0 420662.Mpe_A1225 6.934e-101 341.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,2VZ4H@28216|Betaproteobacteria,1KN47@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 DYD3_k127_1456559_1 83406.HDN1F_30190 2.185e-18 92.0 COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,1SEZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8 DYD3_k127_1494055_0 713587.THITH_16390 1.478e-109 380.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1WX5E@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,SLT_L DYD3_k127_1494055_1 1123519.PSJM300_00360 1.289e-06 52.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0JM@1236|Gammaproteobacteria,1Z2GR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E aminopeptidase - - - - - - - - - - - - Aminopep DYD3_k127_1518781_5 398580.Dshi_3038 1.48e-40 159.0 COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2TRPA@28211|Alphaproteobacteria 28211|Alphaproteobacteria K tetR family - - - - - - - - - - - - TetR_C_11,TetR_N DYD3_k127_1518781_2 572477.Alvin_1456 4.622e-73 257.0 COG1566@1|root,COG1566@2|Bacteria,1RBK7@1224|Proteobacteria,1S241@1236|Gammaproteobacteria,1X2HT@135613|Chromatiales 135613|Chromatiales V HlyD family secretion protein - - - ko:K01993 - - - - ko00000 - - - HlyD_3 DYD3_k127_1518781_1 572477.Alvin_1457 2.209e-115 393.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWJJ@135613|Chromatiales 135613|Chromatiales V PFAM ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_1518781_0 1122185.N792_07230 1.34e-115 388.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,1X52V@135614|Xanthomonadales 135614|Xanthomonadales V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD3_k127_1518781_3 1123279.ATUS01000001_gene1755 6.762e-62 219.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1J64K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K helix_turn_helix, Lux Regulon fixJ - - - - - - - - - - - GerE,Response_reg DYD3_k127_1518781_6 1027273.GZ77_16035 8.651e-20 94.0 COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,1SCNZ@1236|Gammaproteobacteria,1XMVA@135619|Oceanospirillales 135619|Oceanospirillales T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR DYD3_k127_1518781_4 1452718.JBOY01000002_gene468 1.607e-42 167.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria 1236|Gammaproteobacteria T universal stress protein ydaA - - ko:K14055 - - - - ko00000 - - - Usp DYD3_k127_1521720_1 270374.MELB17_07309 3.367e-108 361.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,464WH@72275|Alteromonadaceae 1236|Gammaproteobacteria D Reduces the stability of FtsZ polymers in the presence of ATP zapE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase DYD3_k127_1521720_0 1198232.CYCME_1232 6.928e-255 796.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,4602T@72273|Thiotrichales 72273|Thiotrichales C Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,NAD_binding_8 DYD3_k127_1523799_7 1122134.KB893650_gene30 7.281e-51 186.0 COG0662@1|root,COG0662@2|Bacteria,1R4UW@1224|Proteobacteria,1S3Z7@1236|Gammaproteobacteria,1XPKD@135619|Oceanospirillales 135619|Oceanospirillales G 3-hydroxyanthranilic acid dioxygenase - - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO DYD3_k127_1523799_5 246197.MXAN_0920 1.006e-55 198.0 COG0251@1|root,COG0251@2|Bacteria,1MYEM@1224|Proteobacteria 1224|Proteobacteria J Translation initiation inhibitor, yjgF family - - 3.5.99.5 ko:K15067 ko00380,map00380 - R03887 RC01015 ko00000,ko00001,ko01000 - - - Ribonuc_L-PSP DYD3_k127_1523799_3 754476.Q7A_976 3.057e-84 294.0 COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,460GA@72273|Thiotrichales 72273|Thiotrichales T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP apaH - 3.6.1.41 ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos DYD3_k127_1523799_6 395493.BegalDRAFT_1170 2.119e-51 184.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,46106@72273|Thiotrichales 72273|Thiotrichales P ApaG domain apaG - - ko:K06195 - - - - ko00000 - - - DUF525 DYD3_k127_1523799_4 1217714.F975_00596 1.159e-79 277.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,3NK8E@468|Moraxellaceae 1236|Gammaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD DYD3_k127_1523799_2 1123400.KB904758_gene2306 1.647e-104 349.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,45ZRK@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA DYD3_k127_1523799_1 323261.Noc_1723 4.642e-107 361.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales 135613|Chromatiales M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N DYD3_k127_1523799_0 396588.Tgr7_2714 3.553e-138 457.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales 135613|Chromatiales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C DYD3_k127_1534184_1 278957.ABEA03000163_gene4140 1.07e-91 308.0 COG1368@1|root,COG1368@2|Bacteria,46U99@74201|Verrucomicrobia 74201|Verrucomicrobia M Sulfatase - - - - - - - - - - - - Sulfatase DYD3_k127_1534184_2 572480.Arnit_3135 1.062e-21 104.0 COG3907@1|root,COG3907@2|Bacteria,1MY7B@1224|Proteobacteria,42RAC@68525|delta/epsilon subdivisions,2YQ1I@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S COGs COG3907 PAP2 (acid phosphatase) superfamily protein - - - - - - - - - - - - PAP2 DYD3_k127_1534184_0 349521.HCH_06516 4.709e-95 332.0 COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,1XK5Q@135619|Oceanospirillales 135619|Oceanospirillales M COG4775 Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag DYD3_k127_1534184_3 314285.KT71_12245 1.835e-09 61.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088,ko:K03091 - - - - ko00000,ko03021 - - - Ribosomal_S30AE,Sigma70_r2,Sigma70_r4_2 DYD3_k127_1535290_3 391600.ABRU01000011_gene3317 3.095e-35 138.0 COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,2TSUM@28211|Alphaproteobacteria,2KH4I@204458|Caulobacterales 204458|Caulobacterales H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB DYD3_k127_1535290_1 414684.RC1_2455 2.54e-126 411.0 COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,2TSXQ@28211|Alphaproteobacteria,2JRX6@204441|Rhodospirillales 204441|Rhodospirillales F Inosine-uridine preferring nucleoside hydrolase - - 3.2.2.1 ko:K01239,ko:K01250 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro DYD3_k127_1535290_0 1121878.AUGL01000018_gene22 2.57e-131 430.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family yeiM GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N DYD3_k127_1535290_2 1190606.AJYG01000004_gene764 4.309e-121 398.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XSGE@135623|Vibrionales 135623|Vibrionales F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis deoA GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009032,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C DYD3_k127_1535540_2 1121127.JAFA01000045_gene6772 6.117e-19 92.0 COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,1K1BZ@119060|Burkholderiaceae 28216|Betaproteobacteria C Xanthine dehydrogenase small subunit xdhA - 1.17.1.4 ko:K13481 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 DYD3_k127_1535540_1 62928.azo1184 9.19e-40 153.0 COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,2VUG8@28216|Betaproteobacteria,2KYT7@206389|Rhodocyclales 206389|Rhodocyclales S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily - - 3.5.2.17 ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601 RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin DYD3_k127_1535540_3 94624.Bpet3834 6.001e-14 80.0 2DB8V@1|root,2Z7SX@2|Bacteria,1MX06@1224|Proteobacteria,2VI8T@28216|Betaproteobacteria,3T5KC@506|Alcaligenaceae 28216|Betaproteobacteria S Gluconate 2-dehydrogenase subunit 3 - - 1.1.99.3 ko:K06152 ko00030,ko01100,ko01120,map00030,map01100,map01120 - R01741 RC00084 ko00000,ko00001,ko01000 - - - Gluconate_2-dh3 DYD3_k127_1535540_0 566466.NOR53_631 4.402e-199 634.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,1J5ZV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG2303 Choline dehydrogenase and related flavoproteins - - 1.1.99.3 ko:K06151 ko00030,ko01100,ko01120,map00030,map01100,map01120 - R01741 RC00084 ko00000,ko00001,ko01000 - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 DYD3_k127_1536391_4 497321.C664_06173 3.565e-40 152.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,2KUU7@206389|Rhodocyclales 206389|Rhodocyclales S protease with the C-terminal PDZ domain - - - - - - - - - - - - PDZ_2,Peptidase_M61 DYD3_k127_1536391_0 582515.KR51_00008080 1.225e-101 338.0 COG1834@1|root,COG1915@1|root,COG1834@2|Bacteria,COG1915@2|Bacteria,1G2AU@1117|Cyanobacteria 1117|Cyanobacteria E PFAM LOR SDH bifunctional enzyme conserved region - - - - - - - - - - - - Amidinotransf,Saccharop_dh_N DYD3_k127_1536391_1 929556.Solca_2066 1.53e-96 326.0 COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1IQ05@117747|Sphingobacteriia 976|Bacteroidetes S Amidinotransferase - - - - - - - - - - - - Amidinotransf DYD3_k127_1536391_5 926549.KI421517_gene2748 1.022e-19 94.0 2E3RQ@1|root,32YPC@2|Bacteria,4NRGB@976|Bacteroidetes,47RQ7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_1536391_3 383407.XOC_3087 1.24e-57 220.0 COG4700@1|root,COG4700@2|Bacteria,1R577@1224|Proteobacteria,1S5I8@1236|Gammaproteobacteria,1X5VW@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 DYD3_k127_1536391_2 743720.Psefu_1570 4.501e-81 280.0 COG2267@1|root,COG2267@2|Bacteria,1RDSZ@1224|Proteobacteria,1SYXV@1236|Gammaproteobacteria,1YZJP@136845|Pseudomonas putida group 1236|Gammaproteobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 DYD3_k127_1554012_1 314285.KT71_05987 3.539e-135 439.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RPAA@1236|Gammaproteobacteria,1J6UF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_8 DYD3_k127_1554012_3 565045.NOR51B_1255 9.763e-46 173.0 29JGM@1|root,306DZ@2|Bacteria,1RFV2@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 DYD3_k127_1554012_4 278957.ABEA03000013_gene2660 1.106e-05 55.0 2DMI2@1|root,32RP8@2|Bacteria,46Y4T@74201|Verrucomicrobia,3K8XN@414999|Opitutae 414999|Opitutae - - - - - - - - - - - - - - - DYD3_k127_1554012_0 1123073.KB899243_gene773 2.651e-174 568.0 COG0427@1|root,COG0427@2|Bacteria,1PJY0@1224|Proteobacteria,1RPS6@1236|Gammaproteobacteria,1X3GP@135614|Xanthomonadales 135614|Xanthomonadales C acetyl-coa hydrolase - - - - - - - - - - - - AcetylCoA_hyd_C DYD3_k127_1554012_2 1348657.M622_02470 1.278e-47 173.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2VHMU@28216|Betaproteobacteria,2KVDG@206389|Rhodocyclales 206389|Rhodocyclales O DnaJ molecular chaperone homology domain - - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C DYD3_k127_1566269_0 713586.KB900536_gene582 3.248e-126 416.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1WYRX@135613|Chromatiales 135613|Chromatiales S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC DYD3_k127_1566269_1 1195246.AGRI_00040 5.959e-77 264.0 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,46407@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yciK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - - - - - - - - - - adh_short DYD3_k127_1577878_7 511062.GU3_05630 1.558e-32 130.0 COG2010@1|root,COG2010@2|Bacteria,1N5P8@1224|Proteobacteria,1S9K3@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C DYD3_k127_1577878_5 1280390.CBQR020000078_gene1746 5.008e-55 198.0 COG0454@1|root,COG0454@2|Bacteria,1V4EA@1239|Firmicutes,4HHBF@91061|Bacilli,26XFF@186822|Paenibacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain ysnE GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - ko:K03829 - - - - ko00000,ko01000 - - - Acetyltransf_1 DYD3_k127_1577878_8 450851.PHZ_c2202 6.817e-29 129.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B DYD3_k127_1577878_1 247634.GPB2148_2100 4.524e-158 507.0 COG0477@1|root,COG2814@2|Bacteria,1R9EU@1224|Proteobacteria,1S0HE@1236|Gammaproteobacteria,1J8S9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EGP GEPR COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_1577878_0 1547437.LL06_16450 2.859e-203 641.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,43IEF@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 DYD3_k127_1577878_3 1122137.AQXF01000003_gene2096 2.225e-137 443.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Prokaryotic protein of - - - - - - - - - - - - BKACE DYD3_k127_1577878_6 1336235.JAEG01000009_gene2769 2.709e-35 142.0 COG0454@1|root,COG0456@2|Bacteria,1N581@1224|Proteobacteria,2VAHD@28211|Alphaproteobacteria,4BFWR@82115|Rhizobiaceae 28211|Alphaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD3_k127_1577878_2 570952.ATVH01000019_gene717 1.681e-147 474.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria,2JPMF@204441|Rhodospirillales 204441|Rhodospirillales BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl DYD3_k127_1577878_4 1042377.AFPJ01000036_gene1144 1.083e-124 413.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,465EF@72275|Alteromonadaceae 1236|Gammaproteobacteria C Na H antiporter mleN - - - - - - - - - - - Na_H_antiporter DYD3_k127_1622492_0 1192759.AKIB01000026_gene2170 4.312e-107 360.0 COG2271@1|root,COG2271@2|Bacteria,1P3P1@1224|Proteobacteria,2TVM7@28211|Alphaproteobacteria,2K00U@204457|Sphingomonadales 204457|Sphingomonadales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_1622492_2 379066.GAU_0029 1.13e-23 109.0 COG2968@1|root,COG2968@2|Bacteria,1ZTTR@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Protein of unknown function (DUF541) - - - ko:K09807 - - - - ko00000 - - - SIMPL DYD3_k127_1622492_1 269482.Bcep1808_1834 1.474e-86 296.0 28MSW@1|root,2ZB15@2|Bacteria,1PSQ1@1224|Proteobacteria,2VZGB@28216|Betaproteobacteria,1K69Z@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_1627700_1 545696.HOLDEFILI_00752 6.082e-54 193.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,3VNZH@526524|Erysipelotrichia 526524|Erysipelotrichia F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase DYD3_k127_1627700_2 1237149.C900_00291 3.301e-46 170.0 2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 DYD3_k127_1627700_4 1005048.CFU_3298 7.642e-38 145.0 COG5580@1|root,COG5580@2|Bacteria,1NMBI@1224|Proteobacteria,2W5GZ@28216|Betaproteobacteria 28216|Betaproteobacteria O Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD3_k127_1627700_5 697282.Mettu_4352 5.01e-31 124.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XFIY@135618|Methylococcales 135618|Methylococcales K PFAM Cold-shock protein, DNA-binding - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD3_k127_1627700_0 1201293.AKXQ01000023_gene4203 2.042e-153 494.0 COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 DYD3_k127_1627700_3 1207063.P24_10006 6.667e-41 155.0 COG0346@1|root,COG0346@2|Bacteria,1N3K0@1224|Proteobacteria,2UIW1@28211|Alphaproteobacteria,2JXAR@204441|Rhodospirillales 204441|Rhodospirillales E lactoylglutathione lyase activity - - - - - - - - - - - - - DYD3_k127_1638336_8 760117.JN27_06100 1.413e-26 113.0 COG2199@1|root,COG3159@1|root,COG3159@2|Bacteria,COG3706@2|Bacteria,1R8F2@1224|Proteobacteria,2VJGD@28216|Betaproteobacteria,472P5@75682|Oxalobacteraceae 28216|Betaproteobacteria T Protein of unknown function, DUF484 - - - - - - - - - - - - DUF484,GGDEF DYD3_k127_1638336_3 557598.LHK_02634 1.384e-56 215.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,2KQP6@206351|Neisseriales 206351|Neisseriales P Bacterial extracellular solute-binding protein fbpA - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_1,SBP_bac_6,SBP_bac_8 DYD3_k127_1638336_1 1166948.JPZL01000001_gene2547 1.146e-97 329.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1XIU2@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD DYD3_k127_1638336_2 187272.Mlg_0427 2.295e-65 230.0 COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales 135613|Chromatiales L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX DYD3_k127_1638336_5 1123400.KB904769_gene2854 2.073e-41 159.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,460VS@72273|Thiotrichales 72273|Thiotrichales S PFAM Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 DYD3_k127_1638336_9 1279017.AQYJ01000020_gene1205 2.699e-23 110.0 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,467DY@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_1638336_6 395493.BegalDRAFT_1306 8.703e-34 135.0 COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,461BH@72273|Thiotrichales 72273|Thiotrichales M Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin DYD3_k127_1638336_4 472759.Nhal_3569 4.72e-50 180.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1WYPN@135613|Chromatiales 135613|Chromatiales C Iron--sulfur cluster insertion protein erpA erpA - - ko:K15724 - - - - ko00000 - - - Fe-S_biosyn DYD3_k127_1638336_0 396588.Tgr7_2467 5.361e-138 455.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,1WWTY@135613|Chromatiales 135613|Chromatiales FP Belongs to the GppA Ppx family - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA DYD3_k127_1638336_7 498211.CJA_3560 1.634e-27 113.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1FG8H@10|Cellvibrio 1236|Gammaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - iJN746.PP_5217 PP_kinase,PP_kinase_C,PP_kinase_N DYD3_k127_1645987_1 765912.Thimo_1246 8.403e-91 308.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1WWQE@135613|Chromatiales 135613|Chromatiales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD3_k127_1645987_3 1121013.P873_08590 2.631e-68 236.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1X4UT@135614|Xanthomonadales 135614|Xanthomonadales J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase DYD3_k127_1645987_2 1026882.MAMP_00785 6.854e-89 309.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,461TR@72273|Thiotrichales 72273|Thiotrichales S Lysin motif - - - - - - - - - - - - LysM DYD3_k127_1645987_0 472759.Nhal_3814 6.861e-111 369.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1WWKX@135613|Chromatiales 135613|Chromatiales LU TIGRFAM DNA protecting protein DprA - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A DYD3_k127_1645987_4 1026882.MAMP_00782 8.015e-46 170.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,4612G@72273|Thiotrichales 72273|Thiotrichales S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 DYD3_k127_1645987_5 472759.Nhal_3812 4.349e-31 124.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales 135613|Chromatiales L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom DYD3_k127_1652007_5 1123257.AUFV01000026_gene9 8.131e-19 96.0 2DQ0C@1|root,33473@2|Bacteria,1NAM4@1224|Proteobacteria,1SCY6@1236|Gammaproteobacteria,1XB49@135614|Xanthomonadales 135614|Xanthomonadales S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 DYD3_k127_1652007_1 247490.KSU1_C0123 4.636e-203 641.0 COG0151@1|root,COG0151@2|Bacteria 2|Bacteria F phosphoribosylamine-glycine ligase activity purD - 6.3.4.13,6.3.5.5 ko:K01945,ko:K01955 ko00230,ko00240,ko00250,ko01100,ko01110,ko01130,map00230,map00240,map00250,map01100,map01110,map01130 M00048,M00051 R00256,R00575,R01395,R04144,R10948,R10949 RC00002,RC00010,RC00043,RC00090,RC00166,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_3,GARS_A,GARS_C,GARS_N DYD3_k127_1652007_3 1123228.AUIH01000008_gene2428 1.343e-91 320.0 COG2807@1|root,COG2807@2|Bacteria,1NXQ2@1224|Proteobacteria,1RXXM@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_1652007_4 96561.Dole_1891 5.761e-48 180.0 COG0454@1|root,COG1181@1|root,COG0456@2|Bacteria,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2MHWK@213118|Desulfobacterales 28221|Deltaproteobacteria F Belongs to the D-alanine--D-alanine ligase family ddlB1 - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD3_k127_1652007_0 1121374.KB891575_gene1187 1.092e-286 890.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RPCH@1236|Gammaproteobacteria 1236|Gammaproteobacteria BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl DYD3_k127_1652007_2 1121374.KB891575_gene1186 7.949e-117 386.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,1SKJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the D-alanine--D-alanine ligase family - - - - - - - - - - - - Dala_Dala_lig_C DYD3_k127_1652007_6 530564.Psta_3377 5.206e-06 49.0 COG1181@1|root,COG1181@2|Bacteria,2IYQF@203682|Planctomycetes 203682|Planctomycetes M Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD3_k127_165421_3 1026882.MAMP_01332 5.07e-11 75.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD3_k127_165421_2 1002339.HMPREF9373_0441 4.534e-28 123.0 COG1309@1|root,COG1309@2|Bacteria,1QV5P@1224|Proteobacteria,1SA6I@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N DYD3_k127_165421_1 697282.Mettu_4101 1.465e-62 233.0 COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,1RQRT@1236|Gammaproteobacteria,1XGCF@135618|Methylococcales 135618|Methylococcales C XdhC and CoxI family - - - - - - - - - - - - XdhC_C,XdhC_CoxI DYD3_k127_165421_0 864069.MicloDRAFT_00040680 1.962e-97 331.0 COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2TSXR@28211|Alphaproteobacteria,1JTZI@119045|Methylobacteriaceae 28211|Alphaproteobacteria S VWA domain containing CoxE-like protein MA20_09405 - - ko:K07161 - - - - ko00000 - - - VWA_CoxE DYD3_k127_1657854_3 1396141.BATP01000027_gene1109 3.165e-10 62.0 COG4775@1|root,COG4775@2|Bacteria,46UZC@74201|Verrucomicrobia,2IV9A@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Surface antigen - - - - - - - - - - - - Bac_surface_Ag DYD3_k127_1657854_2 1265313.HRUBRA_02382 8.762e-45 167.0 COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,1S4NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1226 Kef-type K transport systems - - - - - - - - - - - - Ion_trans_2 DYD3_k127_1657854_0 861299.J421_1695 4.702e-153 501.0 COG0457@1|root,COG0457@2|Bacteria,1ZV58@142182|Gemmatimonadetes 142182|Gemmatimonadetes S chaperone-mediated protein folding - - - - - - - - - - - - - DYD3_k127_1657854_1 215803.DB30_3065 1.812e-67 232.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YXXC@29|Myxococcales 28221|Deltaproteobacteria E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD3_k127_1672226_0 566466.NOR53_2589 1.155e-130 429.0 COG2207@1|root,COG2207@2|Bacteria,1R73I@1224|Proteobacteria,1SYD3@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 DYD3_k127_1675470_4 1279038.KB907337_gene546 1.996e-07 53.0 COG3467@1|root,COG3467@2|Bacteria,1MWQE@1224|Proteobacteria,2TR7J@28211|Alphaproteobacteria,2JS97@204441|Rhodospirillales 204441|Rhodospirillales S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 DYD3_k127_1675470_0 1279017.AQYJ01000026_gene378 9.57e-214 686.0 COG1629@1|root,COG4771@2|Bacteria,1QYDM@1224|Proteobacteria,1RYCH@1236|Gammaproteobacteria,469WZ@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_1675470_2 876044.IMCC3088_2133 7.496e-53 193.0 COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1J6RA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N DYD3_k127_1675470_1 1254432.SCE1572_37375 2.027e-159 516.0 COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2WM3N@28221|Deltaproteobacteria,2YUFY@29|Myxococcales 28221|Deltaproteobacteria K AlkA N-terminal domain - - 3.2.2.21 ko:K13529,ko:K13530 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD DYD3_k127_1675470_3 1117647.M5M_19205 7.874e-23 97.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1J4DZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD3_k127_1679965_2 153948.NAL212_1173 7.417e-14 77.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,3732H@32003|Nitrosomonadales 28216|Betaproteobacteria S Phosphoribosyl transferase domain comF - - - - - - - - - - - Pribosyltran DYD3_k127_1679965_1 767434.Fraau_0171 2.344e-54 201.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1X53I@135614|Xanthomonadales 135614|Xanthomonadales H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway bioC - 2.1.1.197 ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 DYD3_k127_1679965_0 1123257.AUFV01000009_gene2225 1.255e-67 235.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1X3IF@135614|Xanthomonadales 135614|Xanthomonadales C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 DYD3_k127_1680027_2 1121374.KB891575_gene800 9.918e-22 107.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_8 DYD3_k127_1680027_1 1380380.JIAX01000008_gene1844 2.932e-55 205.0 COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,2TWKE@28211|Alphaproteobacteria 28211|Alphaproteobacteria E reductase - - - - - - - - - - - - MTHFR DYD3_k127_1680027_0 565045.NOR51B_2425 4.858e-173 566.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria,1J9C4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8 DYD3_k127_1680027_3 1411685.U062_00919 2.158e-07 56.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T5NT@1236|Gammaproteobacteria,1J930@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_172112_4 99598.Cal7507_5351 3.43e-76 260.0 COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria,1HKXG@1161|Nostocales 1117|Cyanobacteria E DegT DnrJ EryC1 StrS aminotransferase - - - - - - - - - - - - DegT_DnrJ_EryC1 DYD3_k127_172112_2 867845.KI911784_gene2080 5.088e-93 324.0 COG1670@1|root,COG3980@1|root,COG1670@2|Bacteria,COG3980@2|Bacteria 2|Bacteria M transferase activity, transferring hexosyl groups pseG - 3.6.1.57 ko:K15897 ko00520,map00520 - R09834 RC00005,RC00078 ko00000,ko00001,ko01000 - - - Acetyltransf_3,Glyco_tran_28_C DYD3_k127_172112_0 477974.Daud_1772 3.041e-131 438.0 COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,2621V@186807|Peptococcaceae 186801|Clostridia M TIGRFAM pseudaminic acid synthase pseI - 2.5.1.56,2.5.1.97 ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 - R01804,R04435,R09841 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF DYD3_k127_172112_5 411479.BACUNI_02985 1.501e-64 235.0 COG1083@1|root,COG1083@2|Bacteria,4NM98@976|Bacteroidetes,2FR2G@200643|Bacteroidia,4AQDY@815|Bacteroidaceae 976|Bacteroidetes M Psort location Cytoplasmic, score pseF - - - - - - - - - - - CTP_transf_3 DYD3_k127_172112_3 1565314.OA34_11185 7.217e-80 274.0 COG4123@1|root,COG4123@2|Bacteria,1RESR@1224|Proteobacteria,42URT@68525|delta/epsilon subdivisions,2YRS6@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria H Pseudaminic acid biosynthesis-associated methylase - - - - - - - - - - - - - DYD3_k127_172112_1 1453501.JELR01000002_gene623 8.405e-95 321.0 COG0463@1|root,COG0463@2|Bacteria,1MX1N@1224|Proteobacteria,1S06M@1236|Gammaproteobacteria,464R2@72275|Alteromonadaceae 1236|Gammaproteobacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 DYD3_k127_1734719_2 1458357.BG58_28305 1.74e-52 206.0 COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,2WI17@28216|Betaproteobacteria,1KG8X@119060|Burkholderiaceae 28216|Betaproteobacteria D Protein of unknown function (DUF3300) - - - - - - - - - - - - DUF3300 DYD3_k127_1734719_0 1265503.KB905163_gene2322 9.312e-149 484.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria,2Q7E3@267889|Colwelliaceae 1236|Gammaproteobacteria K PFAM aminotransferase class I and II, regulatory protein GntR HTH - - - - - - - - - - - - Aminotran_1_2,GntR DYD3_k127_1734719_1 28229.ND2E_1540 2.331e-81 284.0 COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,1RNSM@1236|Gammaproteobacteria,2Q7SW@267889|Colwelliaceae 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD3_k127_1734719_4 317655.Sala_1851 1.765e-12 74.0 2BXHN@1|root,349E3@2|Bacteria,1P27F@1224|Proteobacteria,2UWQ3@28211|Alphaproteobacteria,2KC0P@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD3_k127_1734719_3 314285.KT71_08279 1.584e-41 156.0 COG1764@1|root,COG1764@2|Bacteria,1RJIP@1224|Proteobacteria,1S6QM@1236|Gammaproteobacteria,1J9ZC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation - - - - - - - - - - - - OsmC DYD3_k127_1748487_5 32042.PstZobell_16471 6.72e-13 73.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1Z0S7@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S family transcriptional regulator rodZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 DYD3_k127_1748487_1 870187.Thini_0837 4.754e-163 524.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,4606I@72273|Thiotrichales 72273|Thiotrichales J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His DYD3_k127_1748487_4 1283300.ATXB01000001_gene1611 9.417e-31 130.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1XF0Z@135618|Methylococcales 135618|Methylococcales S Tetratricopeptide repeat-like domain - - - - - - - - - - - - TPR_21 DYD3_k127_1748487_3 395493.BegalDRAFT_3451 1.296e-86 301.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,460F4@72273|Thiotrichales 72273|Thiotrichales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamB - - ko:K17713 - - - - ko00000,ko02000 1.B.33.1 - - PQQ_2,PQQ_3 DYD3_k127_1748487_0 768671.ThimaDRAFT_0777 3.27e-165 531.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1WVW6@135613|Chromatiales 135613|Chromatiales S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 DYD3_k127_1748487_2 84531.JMTZ01000011_gene3039 3.225e-95 319.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1X47D@135614|Xanthomonadales 135614|Xanthomonadales E Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD3_k127_1783619_0 84531.JMTZ01000007_gene3450 7.636e-132 436.0 COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RR2N@1236|Gammaproteobacteria,1X3V4@135614|Xanthomonadales 135614|Xanthomonadales G Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 DYD3_k127_1783619_1 1122194.AUHU01000003_gene2080 3.211e-118 396.0 COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,1RR99@1236|Gammaproteobacteria,464X5@72275|Alteromonadaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 DYD3_k127_1783619_2 396588.Tgr7_2584 5.847e-72 244.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1WYBE@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0178 family - - - ko:K09768 - - - - ko00000 - - - DUF188 DYD3_k127_1797107_2 1116472.MGMO_26c00010 3.867e-11 63.0 COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,1T5IA@1236|Gammaproteobacteria 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA DYD3_k127_1797107_0 29581.BW37_00080 2.454e-89 300.0 COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2VH95@28216|Betaproteobacteria,472S2@75682|Oxalobacteraceae 28216|Betaproteobacteria O Glutathione S-transferase, C-terminal domain gstA - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_3,GST_N,GST_N_3 DYD3_k127_1797107_1 1298593.TOL_1526 5.276e-15 80.0 COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1XKRC@135619|Oceanospirillales 135619|Oceanospirillales T Universal stress protein family - - - ko:K14055 - - - - ko00000 - - - Usp DYD3_k127_1808133_2 1443665.JACA01000003_gene602 3.072e-71 242.0 COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,1HZJK@117743|Flavobacteriia 976|Bacteroidetes S COG2366 Protein related to penicillin acylase - - - - - - - - - - - - Penicil_amidase DYD3_k127_1808133_1 1304865.JAGF01000001_gene120 1.326e-82 285.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4F0HN@85016|Cellulomonadaceae 201174|Actinobacteria V TIGRFAM daunorubicin resistance ABC transporter ATPase subunit - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 DYD3_k127_1808133_4 997346.HMPREF9374_2944 1.013e-11 77.0 COG0842@1|root,COG0842@2|Bacteria,1UYSF@1239|Firmicutes,4HEYE@91061|Bacilli,27CQI@186824|Thermoactinomycetaceae 91061|Bacilli V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 DYD3_k127_1808133_3 316274.Haur_1889 5.705e-27 128.0 COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi 200795|Chloroflexi V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 DYD3_k127_1808133_0 1049564.TevJSym_ac00480 4.119e-176 561.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlE GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C DYD3_k127_1812599_1 566466.NOR53_2597 4.69e-65 236.0 COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,1RMBH@1236|Gammaproteobacteria,1J6WP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria yafD - - - - - - - - - - - Exo_endo_phos DYD3_k127_1812599_2 933262.AXAM01000106_gene2632 1.053e-05 55.0 28PW7@1|root,32EDN@2|Bacteria,1N0AP@1224|Proteobacteria,42UF5@68525|delta/epsilon subdivisions,2WQ2P@28221|Deltaproteobacteria,2MKES@213118|Desulfobacterales 28221|Deltaproteobacteria S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 DYD3_k127_1812599_0 472759.Nhal_2573 5.085e-81 276.0 COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WZYU@135613|Chromatiales 135613|Chromatiales S peptidase M48, Ste24p - - - - - - - - - - - - Peptidase_M48,TPR_16 DYD3_k127_1826816_1 1415780.JPOG01000001_gene2810 1.112e-144 463.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,1RQ62@1236|Gammaproteobacteria,1X3MM@135614|Xanthomonadales 135614|Xanthomonadales S AAA domain (Cdc48 subfamily) - - - - - - - - - - - - AAA,AAA_5 DYD3_k127_1826816_0 414684.RC1_0905 1.473e-175 564.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2JQTH@204441|Rhodospirillales 204441|Rhodospirillales S protein conserved in bacteria - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE DYD3_k127_1826816_8 1163617.SCD_n00993 7.135e-55 198.0 COG1225@1|root,COG1225@2|Bacteria,1RH4P@1224|Proteobacteria,2VT1P@28216|Betaproteobacteria 28216|Betaproteobacteria O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD3_k127_1826816_5 187272.Mlg_1761 6.223e-105 353.0 COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,1WYC3@135613|Chromatiales 135613|Chromatiales S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin DYD3_k127_1826816_6 396588.Tgr7_0722 8.555e-92 312.0 COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1WW9Z@135613|Chromatiales 135613|Chromatiales S Displays ATPase and GTPase activities - - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 DYD3_k127_1826816_11 1209072.ALBT01000047_gene452 1.527e-33 138.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1FH8H@10|Cellvibrio 1236|Gammaproteobacteria G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 DYD3_k127_1826816_10 395493.BegalDRAFT_2838 7.527e-35 137.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,46133@72273|Thiotrichales 72273|Thiotrichales J Sigma 54 modulation protein yhbH - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE DYD3_k127_1826816_2 1226994.AMZB01000100_gene1064 1.941e-131 434.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1YESE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD DYD3_k127_1826816_4 395493.BegalDRAFT_2836 1.398e-105 350.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,45ZYJ@72273|Thiotrichales 72273|Thiotrichales S ABC transporter, ATP-binding protein lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C DYD3_k127_1826816_12 742823.HMPREF9465_00554 8.883e-10 68.0 COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,4PQYW@995019|Sutterellaceae 28216|Betaproteobacteria S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane lptA - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA DYD3_k127_1826816_13 232348.ADXL01000007_gene756 1.377e-09 66.0 COG3117@1|root,COG3117@2|Bacteria 2|Bacteria P lipopolysaccharide transmembrane transporter activity lptC GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0017089,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - ko:K02040,ko:K11719 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1,3.A.1.7 - iB21_1397.B21_03015,iECBD_1354.ECBD_0543,iECB_1328.ECB_03064,iECD_1391.ECD_03064 LptC DYD3_k127_1826816_9 1120970.AUBZ01000004_gene345 3.177e-42 162.0 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,467ND@72275|Alteromonadaceae 1236|Gammaproteobacteria S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate kdsC GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECO26_1355.ECO26_4302 Hydrolase_3 DYD3_k127_1826816_3 1123256.KB907929_gene3320 2.014e-127 415.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1X3K3@135614|Xanthomonadales 135614|Xanthomonadales M Arabinose 5-phosphate isomerase kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS DYD3_k127_1826816_7 1049564.TevJSym_ak00870 1.415e-84 291.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1J4U9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P antiporter yrbG - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD3_k127_1826910_2 1269813.ATUL01000004_gene2247 3.721e-06 52.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1WYPF@135613|Chromatiales 135613|Chromatiales L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - AAA_23,SMC_N DYD3_k127_1826910_0 713586.KB900536_gene2143 0.0 1120.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales 135613|Chromatiales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD3_k127_1826910_1 314285.KT71_02627 2.792e-17 85.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - DYD3_k127_1830353_0 203122.Sde_3419 5.795e-147 501.0 COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria,464KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748,OmpA DYD3_k127_1830353_2 1297742.A176_06689 7.802e-54 202.0 COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,439F3@68525|delta/epsilon subdivisions,2X4QF@28221|Deltaproteobacteria,2YZE7@29|Myxococcales 28221|Deltaproteobacteria S glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase DYD3_k127_1830353_1 566466.NOR53_696 6.847e-83 281.0 COG3544@1|root,COG3544@2|Bacteria,1N0KY@1224|Proteobacteria,1SBTF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 DYD3_k127_1834370_0 396588.Tgr7_1990 9.401e-185 595.0 COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg DYD3_k127_1851105_0 1121937.AUHJ01000001_gene546 6.763e-198 629.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,4663U@72275|Alteromonadaceae 1236|Gammaproteobacteria G COG4993 Glucose dehydrogenase adhA - 1.1.2.8,1.1.9.1 ko:K00114,ko:K17760 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD3_k127_1851105_1 573065.Astex_1467 7.399e-08 59.0 COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,2U0MU@28211|Alphaproteobacteria,2KH58@204458|Caulobacterales 204458|Caulobacterales K AefR-like transcriptional repressor, C-terminal region - - - - - - - - - - - - TetR_C_7,TetR_N DYD3_k127_1852078_4 382464.ABSI01000006_gene874 2.105e-17 89.0 COG1595@1|root,COG1595@2|Bacteria,46XM2@74201|Verrucomicrobia,2IW65@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_1852078_1 314285.KT71_02892 1.006e-222 706.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1J7SK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD3_k127_1852078_3 247634.GPB2148_880 9.131e-54 192.0 COG3450@1|root,COG3450@2|Bacteria,1N21T@1224|Proteobacteria,1SBKQ@1236|Gammaproteobacteria,1JA60@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S enzyme of the cupin superfamily - - - ko:K06995 - - - - ko00000 - - - Cupin_3 DYD3_k127_1852078_2 314285.KT71_15254 1.169e-195 619.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1J8QU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Na+/H+ antiporter family - - - - - - - - - - - - Na_H_antiporter DYD3_k127_1852078_0 566466.NOR53_1065 3.326e-242 763.0 COG1231@1|root,COG1231@2|Bacteria,1QXX6@1224|Proteobacteria,1T3IZ@1236|Gammaproteobacteria,1J5KT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - 1.5.99.6 ko:K00316 ko00330,ko00410,ko01100,map00330,map00410,map01100 - R01914,R01915 RC00053,RC00225 ko00000,ko00001,ko01000 - - - NAD_binding_8 DYD3_k127_189075_2 1304877.KI519400_gene638 5.622e-57 202.0 COG2030@1|root,COG2030@2|Bacteria,1MUR2@1224|Proteobacteria,2TUM7@28211|Alphaproteobacteria,3JR27@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydrat_N,MaoC_dehydratas DYD3_k127_189075_1 1112204.GPOL_c17840 8.191e-67 237.0 COG1024@1|root,COG1024@2|Bacteria,2GKC4@201174|Actinobacteria,4GCQG@85026|Gordoniaceae 201174|Actinobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 DYD3_k127_189075_4 1163407.UU7_14550 2.473e-07 61.0 COG0790@1|root,COG0790@2|Bacteria,1R909@1224|Proteobacteria,1SXRX@1236|Gammaproteobacteria,1X6NK@135614|Xanthomonadales 135614|Xanthomonadales S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - - DYD3_k127_189075_3 1280944.HY17_06015 8.141e-53 193.0 COG1309@1|root,COG1309@2|Bacteria,1R7F8@1224|Proteobacteria,2U0DG@28211|Alphaproteobacteria,43YV2@69657|Hyphomonadaceae 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N DYD3_k127_189075_0 1123253.AUBD01000008_gene518 0.0 1455.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1X3T3@135614|Xanthomonadales 135614|Xanthomonadales EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase DYD3_k127_1926665_2 402881.Plav_0618 4.36e-78 265.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,1JN17@119043|Rhodobiaceae 28211|Alphaproteobacteria S PFAM aminoglycoside phosphotransferase MA20_31030 - - - - - - - - - - - APH DYD3_k127_1926665_1 246197.MXAN_7310 1.384e-127 413.0 COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,42YTV@68525|delta/epsilon subdivisions,2WTY1@28221|Deltaproteobacteria,2YYUF@29|Myxococcales 28221|Deltaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - ko:K13775 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short DYD3_k127_1926665_0 1304883.KI912532_gene719 1.178e-212 666.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,2KVX8@206389|Rhodocyclales 206389|Rhodocyclales I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD3_k127_1927349_3 396588.Tgr7_0458 1.151e-97 325.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1WYS8@135613|Chromatiales 135613|Chromatiales KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - HAMP,HEAT_2,Pkinase,sCache_3_2 DYD3_k127_1927349_1 713586.KB900536_gene2578 1.093e-164 524.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - - - - - - - - - - T2SSE DYD3_k127_1927349_2 713586.KB900536_gene2579 5.576e-134 435.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD3_k127_1927349_0 1049564.TevJSym_af01070 1.549e-209 661.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1J4VI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446 Anticodon_1,tRNA-synt_1g,tRNA_bind DYD3_k127_1965138_1 76114.ebA3896 1.053e-47 177.0 COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3014) - - - - - - - - - - - - DUF3014 DYD3_k127_1965138_0 1121875.KB907549_gene1852 1.888e-262 827.0 COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1HXHX@117743|Flavobacteriia 976|Bacteroidetes S Transferrin receptor-like dimerisation domain - - 3.4.17.21 ko:K01301 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28,TFR_dimer DYD3_k127_1965142_5 1163408.UU9_02454 1.979e-26 123.0 COG0745@1|root,COG2199@1|root,COG2200@1|root,COG0745@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1X47Y@135614|Xanthomonadales 135614|Xanthomonadales T COG2202 FOG PAS PAC domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9 DYD3_k127_1965142_0 713586.KB900536_gene86 1.465e-92 307.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1WX8C@135613|Chromatiales 135613|Chromatiales J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C DYD3_k127_1965142_3 94122.Shewana3_1776 5.427e-51 192.0 COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,1S6QU@1236|Gammaproteobacteria,2QBS9@267890|Shewanellaceae 1236|Gammaproteobacteria T PFAM GAF domain protein yebR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0033745,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 DYD3_k127_1965142_1 935567.JAES01000003_gene223 8.447e-81 282.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1X456@135614|Xanthomonadales 135614|Xanthomonadales J Elongation factor P--(R)-beta-lysine ligase lysS - - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 DYD3_k127_1965142_2 1249627.D779_4103 2.511e-69 246.0 COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria,1WWNF@135613|Chromatiales 135613|Chromatiales I Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase DYD3_k127_1965142_6 1123053.AUDG01000008_gene3620 5.736e-17 87.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1WYZ4@135613|Chromatiales 135613|Chromatiales S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC DYD3_k127_1965142_4 1123257.AUFV01000001_gene1551 3.558e-33 138.0 COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria,1XCSH@135614|Xanthomonadales 135614|Xanthomonadales S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC DYD3_k127_1965142_7 396588.Tgr7_1236 3.668e-09 62.0 COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,1WWX2@135613|Chromatiales 135613|Chromatiales J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue prmB - 2.1.1.298 ko:K07320 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03009 - - - MTS DYD3_k127_1973222_3 1122612.AUBA01000015_gene880 6.214e-30 120.0 COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,2U1WS@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 DYD3_k127_1973222_0 1411685.U062_00336 8.982e-153 498.0 COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,1S185@1236|Gammaproteobacteria,1J8BT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR DYD3_k127_1973222_2 748247.AZKH_p0166 8.996e-56 200.0 COG0685@1|root,COG0685@2|Bacteria,1RDXU@1224|Proteobacteria 1224|Proteobacteria E Methylene-tetrahydrofolate reductase C terminal - - - - - - - - - - - - MTHFR_C DYD3_k127_1973222_1 1265505.ATUG01000002_gene1318 2.999e-149 485.0 COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,42U9J@68525|delta/epsilon subdivisions,2WQ39@28221|Deltaproteobacteria 28221|Deltaproteobacteria EGP Uncharacterised MFS-type transporter YbfB - - - ko:K05548,ko:K05819,ko:K08195 - - - - ko00000,ko02000 2.A.1.15 - - MFS_1,MFS_4 DYD3_k127_1973222_4 627192.SLG_06580 0.0003245 43.0 2DJGY@1|root,30638@2|Bacteria,1Q6ZZ@1224|Proteobacteria,2UP6A@28211|Alphaproteobacteria,2K92M@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD3_k127_1987442_3 1118235.CAJH01000010_gene602 2.421e-35 140.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1X3SR@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD3_k127_1987442_0 658187.LDG_5577 1.272e-127 419.0 COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1JCDT@118969|Legionellales 118969|Legionellales E histidinol-phosphatase activity hisB - 3.1.3.15,4.2.1.19 ko:K01089 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_like,IGPD,PNK3P DYD3_k127_1987442_1 1163407.UU7_02442 1.43e-60 214.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1X5IB@135614|Xanthomonadales 135614|Xanthomonadales E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase DYD3_k127_1987442_2 1121948.AUAC01000002_gene958 1.336e-39 154.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,43WXG@69657|Hyphomonadaceae 28211|Alphaproteobacteria E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD3_k127_2005197_3 62928.azo1492 1.681e-53 196.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WEFS@28216|Betaproteobacteria 28216|Betaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - 2.7.13.1 ko:K05962 - - - - ko00000,ko01000 - - - HATPase_c DYD3_k127_2005197_2 1535422.ND16A_3940 1.162e-89 303.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,2Q85G@267889|Colwelliaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE DYD3_k127_2005197_1 757424.Hsero_2712 2.963e-114 376.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2VJB2@28216|Betaproteobacteria,473QV@75682|Oxalobacteraceae 28216|Betaproteobacteria S Serine hydrolase involved in the detoxification of formaldehyde fghA - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase DYD3_k127_2005197_0 1027273.GZ77_02890 4.367e-193 608.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XHMY@135619|Oceanospirillales 135619|Oceanospirillales IQ catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD3_k127_2019036_0 247634.GPB2148_1837 9.201e-98 342.0 COG4773@1|root,COG4773@2|Bacteria,1NRKQ@1224|Proteobacteria,1SJXP@1236|Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_2019036_1 215803.DB30_4904 1.637e-88 305.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria 28221|Deltaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD3_k127_2019036_2 861299.J421_0487 1.547e-41 162.0 COG2936@1|root,COG2936@2|Bacteria,1ZUE2@142182|Gemmatimonadetes 142182|Gemmatimonadetes M X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 DYD3_k127_2072491_0 1174684.EBMC1_03210 1.347e-181 606.0 COG1629@1|root,COG1629@2|Bacteria,1N7IE@1224|Proteobacteria,2TVJS@28211|Alphaproteobacteria,2KCZ8@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_2072491_1 1120960.ATXG01000005_gene2552 1.232e-06 58.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 DYD3_k127_2098715_2 1191460.F959_01566 0.0002615 48.0 COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,1S6SU@1236|Gammaproteobacteria,3NKA1@468|Moraxellaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF962) - - - - - - - - - - - - DUF962 DYD3_k127_2098715_0 1453501.JELR01000001_gene2392 1.759e-166 543.0 COG3291@1|root,COG3291@2|Bacteria,1QU15@1224|Proteobacteria,1T1KN@1236|Gammaproteobacteria,46D2W@72275|Alteromonadaceae 1236|Gammaproteobacteria S Pkd domain containing protein - - - - - - - - - - - - - DYD3_k127_2098715_1 1279017.AQYJ01000025_gene585 8.713e-67 235.0 COG1629@1|root,COG1629@2|Bacteria,1MX4K@1224|Proteobacteria,1RP6B@1236|Gammaproteobacteria,464ZU@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_2117205_2 1121935.AQXX01000120_gene4871 8.633e-136 437.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XIPI@135619|Oceanospirillales 135619|Oceanospirillales E alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp DYD3_k127_2117205_5 420662.Mpe_A3805 2.585e-31 126.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales 28216|Betaproteobacteria S RNA-binding protein - - - - - - - - - - - - RRM_1 DYD3_k127_2117205_4 485915.Dret_0980 2.4e-54 207.0 COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2WKUD@28221|Deltaproteobacteria,2M8FS@213115|Desulfovibrionales 28221|Deltaproteobacteria S CBS domain containing protein - - - - - - - - - - - - CBS,DUF21 DYD3_k127_2117205_1 1237149.C900_03836 1.632e-191 610.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity putP_2 - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF DYD3_k127_2117205_0 1333998.M2A_2698 0.0 1270.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,4BPAA@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD3_k127_2117205_3 1333998.M2A_2699 9.754e-115 381.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VET4@28211|Alphaproteobacteria,4BS39@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_D23 DYD3_k127_2121771_4 796620.VIBC2010_06859 1.245e-13 70.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,1S3QM@1236|Gammaproteobacteria,1XWZB@135623|Vibrionales 135623|Vibrionales S Belongs to the UPF0178 family yaiI - - ko:K09768 - - - - ko00000 - - - DUF188 DYD3_k127_2121771_2 391587.KAOT1_15207 1.155e-76 264.0 COG1272@1|root,COG1272@2|Bacteria,4NM95@976|Bacteroidetes,1HYZQ@117743|Flavobacteriia 976|Bacteroidetes S membrane protein, hemolysin III homolog hly-III - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII DYD3_k127_2121771_1 1385515.N791_06865 4.25e-216 685.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X39Z@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF885 DYD3_k127_2121771_0 861299.J421_4478 3.227e-222 701.0 COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD3_k127_2121771_3 1344012.ATMI01000035_gene2975 1.914e-46 173.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,4BUNR@82986|Tatumella 1236|Gammaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 DYD3_k127_2138825_0 1294143.H681_18855 5.825e-156 501.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminotransferase ybdL - 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 DYD3_k127_2138825_1 5911.EAR83878 3.288e-108 357.0 COG1012@1|root,KOG2451@2759|Eukaryota,3ZB8F@5878|Ciliophora 5878|Ciliophora C Aldehyde dehydrogenase family - - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh DYD3_k127_2156944_16 4787.PITG_09985T0 3.378e-36 141.0 COG0265@1|root,KOG1421@2759|Eukaryota,3Q7R9@4776|Peronosporales 4776|Peronosporales O negative regulation of hippo signaling - - - - - - - - - - - - PDZ_1,Trypsin_2 DYD3_k127_2156944_0 1304275.C41B8_09296 3.667e-236 740.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3318 GDC-P DYD3_k127_2156944_13 1499967.BAYZ01000143_gene6124 7.917e-46 174.0 COG2077@1|root,COG2077@2|Bacteria,2NQ0A@2323|unclassified Bacteria 2|Bacteria O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin DYD3_k127_2156944_2 261292.Nit79A3_1224 8.648e-183 583.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,3720Y@32003|Nitrosomonadales 28216|Betaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P DYD3_k127_2156944_14 713586.KB900536_gene2602 1.545e-42 162.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1WYGS@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H DYD3_k127_2156944_5 396588.Tgr7_2759 4.815e-148 477.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1WWZ0@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C DYD3_k127_2156944_1 472759.Nhal_1913 1.44e-227 720.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X04H@135613|Chromatiales 135613|Chromatiales S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD3_k127_2156944_7 1283300.ATXB01000001_gene157 1.714e-106 354.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1XG64@135618|Methylococcales 135618|Methylococcales HJ Sugar-transfer associated ATP-grasp - - - - - - - - - - - - ATPgrasp_ST DYD3_k127_2156944_4 396588.Tgr7_2936 1.478e-148 485.0 COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales 135613|Chromatiales E 7 transmembrane helices usually fused to an inactive transglutaminase - - - - - - - - - - - - 7TM_transglut,Transglut_i_TM DYD3_k127_2156944_8 765913.ThidrDRAFT_2373 1.464e-88 306.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1WVWX@135613|Chromatiales 135613|Chromatiales CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K18800 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04987,R08768 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD3_k127_2156944_6 396588.Tgr7_2763 1.724e-114 382.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales 135613|Chromatiales CH Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD3_k127_2156944_3 83406.HDN1F_01240 6.799e-182 578.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1J4KM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 DYD3_k127_2156944_19 1122603.ATVI01000005_gene3668 2.103e-19 96.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1X773@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0149 family - - - ko:K09895 - - - - ko00000 - - - UPF0149 DYD3_k127_2156944_20 1260251.SPISAL_08165 4.151e-14 75.0 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SX58@1236|Gammaproteobacteria,1WZBH@135613|Chromatiales 135613|Chromatiales S TIGRFAM TIGR02449 family protein - - - ko:K09892 - - - - ko00000,ko03036 - - - - DYD3_k127_2156944_18 396588.Tgr7_2768 2.033e-22 100.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1WZF3@135613|Chromatiales 135613|Chromatiales D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA DYD3_k127_2156944_17 396588.Tgr7_2769 3.365e-28 121.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1WYDB@135613|Chromatiales 135613|Chromatiales H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig DYD3_k127_2156944_9 243233.MCA0355 1.868e-81 276.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1XED0@135618|Methylococcales 135618|Methylococcales G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A DYD3_k127_2156944_11 1209072.ALBT01000064_gene1163 2.836e-58 205.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1FHCG@10|Cellvibrio 1236|Gammaproteobacteria J Ribosomal protein S9/S16 rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 DYD3_k127_2156944_10 1049564.TevJSym_ak00880 1.011e-66 231.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1J5P3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 DYD3_k127_2156944_12 1123261.AXDW01000007_gene2358 2.533e-46 176.0 COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,1RN4J@1236|Gammaproteobacteria,1X57Z@135614|Xanthomonadales 135614|Xanthomonadales M salt-induced outer membrane protein - - - ko:K07283 - - - - ko00000 - - - DUF481 DYD3_k127_2156944_15 1234364.AMSF01000060_gene963 2.339e-36 141.0 COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1X4J6@135614|Xanthomonadales 135614|Xanthomonadales H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 DYD3_k127_2160526_3 566466.NOR53_1065 5.539e-82 279.0 COG1231@1|root,COG1231@2|Bacteria,1QXX6@1224|Proteobacteria,1T3IZ@1236|Gammaproteobacteria,1J5KT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - 1.5.99.6 ko:K00316 ko00330,ko00410,ko01100,map00330,map00410,map01100 - R01914,R01915 RC00053,RC00225 ko00000,ko00001,ko01000 - - - NAD_binding_8 DYD3_k127_2160526_0 627192.SLG_31090 2.429e-152 499.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2KA1X@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD3_k127_2160526_2 565045.NOR51B_2777 1.334e-135 447.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1T3SF@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF DYD3_k127_2160526_1 1054213.HMPREF9946_04193 1.569e-151 494.0 COG0160@1|root,COG0160@2|Bacteria,1MX0Y@1224|Proteobacteria,2TRAZ@28211|Alphaproteobacteria,2JRF7@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - APH,Aminotran_3,Peptidase_M23 DYD3_k127_2160526_4 349161.Dred_1744 2.337e-08 61.0 COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,24HHK@186801|Clostridia,261SU@186807|Peptococcaceae 186801|Clostridia I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD3_k127_2161979_0 558884.JRGM01000140_gene688 1.249e-280 888.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria 1236|Gammaproteobacteria I acyl-CoA dehydrogenase fadE GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 - ko:K06445 ko00071,ko01100,ko01212,map00071,map01100,map01212 M00087 R01175,R01279,R03777,R03857,R03990,R04751,R04754 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0217 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 DYD3_k127_2161979_1 1479235.KK366039_gene132 7.351e-21 92.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1XIPA@135619|Oceanospirillales 135619|Oceanospirillales C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N DYD3_k127_2164143_0 314285.KT71_03017 1.471e-80 296.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT6@1236|Gammaproteobacteria,1J7Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - DYD3_k127_2164143_1 748247.AZKH_0153 1.449e-48 178.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria 28216|Betaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family kefC - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N DYD3_k127_2185413_1 1158150.KB906241_gene1047 3.306e-60 211.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase - - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 DYD3_k127_2185413_0 1121937.AUHJ01000003_gene3229 5.798e-124 421.0 COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CBM9_1,HATPase_c,HisKA DYD3_k127_2189847_1 1300345.LF41_355 1.155e-15 79.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1X6RA@135614|Xanthomonadales 135614|Xanthomonadales S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,Abhydrolase_8 DYD3_k127_2189847_0 768671.ThimaDRAFT_3378 0.0 1025.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales 135613|Chromatiales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V DYD3_k127_2193345_3 84531.JMTZ01000012_gene3008 4.099e-36 148.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1S617@1236|Gammaproteobacteria,1X75U@135614|Xanthomonadales 135614|Xanthomonadales M Peptidyl-prolyl cis-trans - - 5.2.1.8 ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C DYD3_k127_2193345_2 575588.ACPN01000028_gene719 3.184e-50 181.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,3NN4E@468|Moraxellaceae 1236|Gammaproteobacteria O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR DYD3_k127_2193345_0 314278.NB231_13641 1.373e-59 220.0 COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,1RQWQ@1236|Gammaproteobacteria,1WXWK@135613|Chromatiales 135613|Chromatiales E pfam abc - - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran DYD3_k127_2193345_1 566466.NOR53_3613 4.62e-52 191.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria,1JB3Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) yehZ - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC DYD3_k127_219450_2 297246.lpp1515 1.363e-92 310.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1JCVI@118969|Legionellales 118969|Legionellales C Pyruvate dehydrogenase E1 alpha subunit odpA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD3_k127_219450_0 323261.Noc_1434 2.927e-154 494.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,1WXRY@135613|Chromatiales 135613|Chromatiales C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase - - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C DYD3_k127_219450_1 388051.AUFE01000004_gene965 1.815e-107 362.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,2VPEK@28216|Betaproteobacteria,1K0K3@119060|Burkholderiaceae 28216|Betaproteobacteria C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD3_k127_219450_3 1384056.N787_00770 1.296e-30 128.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1X46R@135614|Xanthomonadales 135614|Xanthomonadales E glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N DYD3_k127_2208304_3 203122.Sde_3249 3.417e-09 59.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria,464DD@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat,SpvB,TcdB_toxin_midN,VCBS DYD3_k127_2208304_5 1117647.M5M_16060 1.175e-06 55.0 2ECUN@1|root,336S5@2|Bacteria,1NCZ7@1224|Proteobacteria,1SDWP@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_2208304_0 861299.J421_4071 1.033e-197 631.0 COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes 2|Bacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD3_k127_2208304_1 1265313.HRUBRA_00541 1.826e-103 344.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1J5VQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S esterase of the alpha-beta hydrolase superfamily rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin DYD3_k127_2208304_2 675815.VOA_002899 2.756e-11 68.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1XX0W@135623|Vibrionales 135623|Vibrionales C cytochrome c5 cycB - - - - - - - - - - - Cytochrome_CBB3 DYD3_k127_2211910_0 316275.VSAL_II1002 2.719e-105 351.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XU2Z@135623|Vibrionales 135623|Vibrionales U COG1115 Na alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp DYD3_k127_2211910_2 679199.HMPREF9332_01213 2.324e-10 72.0 COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,2FPRJ@200643|Bacteroidia,1WCYV@1283313|Alloprevotella 976|Bacteroidetes G Belongs to the carbohydrate kinase PfkB family - - - - - - - - - - - - PfkB DYD3_k127_2211910_1 1201290.M902_2383 1.608e-57 211.0 COG0434@1|root,COG0434@2|Bacteria,1Q83B@1224|Proteobacteria,431HE@68525|delta/epsilon subdivisions,2WWQM@28221|Deltaproteobacteria 28221|Deltaproteobacteria S BtpA family - - - - - - - - - - - - BtpA DYD3_k127_2227392_4 713586.KB900536_gene338 3.96e-12 74.0 COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1WW55@135613|Chromatiales 135613|Chromatiales DM peptidase - - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 DYD3_k127_2227392_2 1454004.AW11_00591 1.203e-69 241.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2VT25@28216|Betaproteobacteria,1KQS7@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc DYD3_k127_2227392_1 322710.Avin_38700 4.152e-77 268.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD3_k127_2227392_0 1286106.MPL1_02578 3.529e-100 335.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,46018@72273|Thiotrichales 72273|Thiotrichales S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE DYD3_k127_2227392_3 1260251.SPISAL_04375 1.41e-38 151.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1X2FV@135613|Chromatiales 135613|Chromatiales S Smr protein - - - - - - - - - - - - Smr DYD3_k127_2246151_1 1479238.JQMZ01000001_gene1005 1.72e-72 259.0 COG2304@1|root,COG2304@2|Bacteria,1PBVT@1224|Proteobacteria,2U3NK@28211|Alphaproteobacteria,43YWS@69657|Hyphomonadaceae 28211|Alphaproteobacteria S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 DYD3_k127_2246151_0 887898.HMPREF0551_2319 1.167e-91 308.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,1K5EX@119060|Burkholderiaceae 28216|Betaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K14392 - - - - ko00000,ko02000 2.A.21.1 - - SSF DYD3_k127_2251146_1 331869.BAL199_11546 3.675e-72 250.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TVAX@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Aminotran_5 DYD3_k127_2251146_0 1042375.AFPL01000046_gene1938 3.84e-132 435.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,465HT@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0733 Na -dependent transporters of the SNF family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD3_k127_2251146_2 543913.D521_1208 1.717e-54 195.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,1KQ1Q@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33,3.8.1.5 ko:K01563,ko:K11991 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223 RC00477,RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000,ko03016 - - - Abhydrolase_1,MafB19-deam,TfoX_C DYD3_k127_2251146_3 396588.Tgr7_1049 2.961e-14 74.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1WXYV@135613|Chromatiales 135613|Chromatiales M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT DYD3_k127_2251507_2 1122194.AUHU01000003_gene2391 8.047e-111 366.0 COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,1RRH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD3_k127_2251507_1 1122194.AUHU01000003_gene2390 7.551e-119 399.0 COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,1RPZF@1236|Gammaproteobacteria,464UM@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD3_k127_2251507_4 1123073.KB899241_gene3294 3.536e-95 316.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1X3CK@135614|Xanthomonadales 135614|Xanthomonadales V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_2251507_3 1122194.AUHU01000003_gene2388 1.916e-98 335.0 COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,466F0@72275|Alteromonadaceae 1236|Gammaproteobacteria M Biotin-lipoyl like acrE - - - - - - - - - - - HlyD_D23 DYD3_k127_2251507_0 1415778.JQMM01000001_gene770 1.252e-139 469.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1J6E9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec DYD3_k127_2251507_6 305900.GV64_04910 1.632e-39 149.0 COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,1S8V6@1236|Gammaproteobacteria,1XMAY@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF962 DYD3_k127_2251507_5 349521.HCH_00950 9.714e-52 192.0 COG2339@1|root,COG2339@2|Bacteria 2|Bacteria D peptidase activity - - - - - - - - - - - - PrsW-protease DYD3_k127_2271085_0 765912.Thimo_2750 1.02e-182 581.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1WXB6@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase DYD3_k127_2271085_1 62928.azo0814 1.07e-19 92.0 COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,2KWVP@206389|Rhodocyclales 206389|Rhodocyclales K Belongs to the BolA IbaG family - - - - - - - - - - - - BolA DYD3_k127_2284173_3 325777.GW15_0204595 4.132e-51 187.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1SA8G@1236|Gammaproteobacteria,1XC86@135614|Xanthomonadales 135614|Xanthomonadales H Molybdopterin-converting factor chain 2 moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE DYD3_k127_2284173_5 1234364.AMSF01000015_gene3111 2.278e-46 174.0 COG0746@1|root,COG0746@2|Bacteria,1PJ8G@1224|Proteobacteria,1T6R6@1236|Gammaproteobacteria,1X7YT@135614|Xanthomonadales 135614|Xanthomonadales H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor - - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 DYD3_k127_2284173_2 1356852.N008_09170 4.89e-56 199.0 COG0315@1|root,COG0315@2|Bacteria,4NHA0@976|Bacteroidetes,47PU9@768503|Cytophagia 976|Bacteroidetes H MoaC family moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC DYD3_k127_2284173_1 1234364.AMSF01000015_gene3113 2.117e-127 416.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1X46A@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM DYD3_k127_2284173_0 247633.GP2143_13041 3.869e-157 530.0 COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPW2@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD3_k127_2284173_4 1279017.AQYJ01000029_gene3535 3.198e-50 185.0 COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,1RPNI@1236|Gammaproteobacteria,464IY@72275|Alteromonadaceae 1236|Gammaproteobacteria I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD3_k127_2297528_1 1163407.UU7_11609 1.051e-77 270.0 28HYC@1|root,2Z83T@2|Bacteria,1QEBM@1224|Proteobacteria,1RRCK@1236|Gammaproteobacteria,1X5W1@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_2297528_0 1122134.KB893650_gene16 5.381e-82 279.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1RS4F@1236|Gammaproteobacteria,1XJ6P@135619|Oceanospirillales 135619|Oceanospirillales S Predicted membrane protein (DUF2238) - - - ko:K08984 - - - - ko00000 - - - DUF2238 DYD3_k127_2297528_3 977880.RALTA_A0184 1.644e-35 141.0 COG0454@1|root,COG0454@2|Bacteria,1QTYF@1224|Proteobacteria,2WHN1@28216|Betaproteobacteria,1KHI7@119060|Burkholderiaceae 28216|Betaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD3_k127_2297528_2 1415778.JQMM01000001_gene425 1.233e-73 256.0 COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,1J75P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6,DUF676,Hydrolase_4,PGAP1 DYD3_k127_2301957_4 1279017.AQYJ01000022_gene2607 1.597e-22 105.0 2C5F4@1|root,31I7F@2|Bacteria,1RHUH@1224|Proteobacteria,1S7M2@1236|Gammaproteobacteria,46BAF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_2301957_1 1279017.AQYJ01000022_gene2606 7.434e-57 207.0 29B18@1|root,2ZY02@2|Bacteria,1REMG@1224|Proteobacteria,1S4B1@1236|Gammaproteobacteria,46AUF@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_2301957_3 1122134.KB893650_gene1311 7.444e-33 134.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,1XS8J@135619|Oceanospirillales 135619|Oceanospirillales M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 DYD3_k127_2301957_0 1384056.N787_04480 1.647e-87 305.0 COG3975@1|root,COG3975@2|Bacteria,1QX25@1224|Proteobacteria,1RWD8@1236|Gammaproteobacteria,1X9T6@135614|Xanthomonadales 135614|Xanthomonadales S protease with the C-terminal PDZ domain - - - - - - - - - - - - - DYD3_k127_2301957_2 105559.Nwat_1244 1.019e-46 173.0 COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales 135613|Chromatiales O PFAM ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA DYD3_k127_2314388_5 2340.JV46_26670 3.234e-30 127.0 2DNYF@1|root,32ZSU@2|Bacteria,1N8ZB@1224|Proteobacteria,1S5ZH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM HupH hydrogenase expression protein - - - ko:K03618 - - - - ko00000 - - - HupH_C DYD3_k127_2314388_3 2340.JV46_26660 8.82e-43 162.0 COG0680@1|root,COG0680@2|Bacteria,1N3AS@1224|Proteobacteria,1SZPN@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Hydrogenase maturation protease - - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI DYD3_k127_2314388_6 243233.MCA1600 3.9e-27 113.0 COG0298@1|root,COG0298@2|Bacteria,1QKV6@1224|Proteobacteria,1SE6V@1236|Gammaproteobacteria 1236|Gammaproteobacteria O TIGRFAM hydrogenase assembly chaperone hypC hupF hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC DYD3_k127_2314388_4 765914.ThisiDRAFT_1290 1.204e-31 131.0 COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria,1WYQN@135613|Chromatiales 135613|Chromatiales S Probably plays a role in a hydrogenase nickel cofactor insertion step hypA - - ko:K04651 - - - - ko00000,ko03110 - - - HypA DYD3_k127_2314388_2 631362.Thi970DRAFT_02664 1.865e-107 360.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,1WWGI@135613|Chromatiales 135613|Chromatiales KO TIGRFAM Hydrogenase accessory protein HypB - - - ko:K04652 - - - - ko00000,ko03110 - - - cobW DYD3_k127_2314388_0 2340.JV46_24290 8.078e-182 576.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1J9VF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Hydrogenase formation hypA family hypD GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - ko:K04654 - - - - ko00000 - - - HypD DYD3_k127_2314388_1 1288494.EBAPG3_2310 3.305e-159 516.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,3743Q@32003|Nitrosomonadales 28216|Betaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF DYD3_k127_2319827_0 1049564.TevJSym_ao00680 2.861e-131 428.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1J4UD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the peptidase S11 family dacA GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664 PBP5_C,Peptidase_S11 DYD3_k127_2319827_3 765910.MARPU_16705 7.956e-20 93.0 COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,1S61Y@1236|Gammaproteobacteria,1WZ34@135613|Chromatiales 135613|Chromatiales S Belongs to the UPF0250 family - - - ko:K09158 - - - - ko00000 - - - DUF493 DYD3_k127_2319827_1 1442599.JAAN01000035_gene655 3.024e-73 257.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1X4H1@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB DYD3_k127_2319827_2 1249627.D779_3881 2.153e-37 144.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales 135613|Chromatiales JM PFAM Nucleotidyl transferase - - 2.7.7.99 ko:K00992 ko00520,ko01100,map00520,map01100 - R11025 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase DYD3_k127_2334810_1 1122221.JHVI01000014_gene1360 1.635e-107 357.0 COG1171@1|root,COG1171@2|Bacteria,1WJZG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD3_k127_2334810_0 1121904.ARBP01000009_gene4348 4.592e-120 400.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47MH5@768503|Cytophagia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 DYD3_k127_2334810_3 112098.XP_008607349.1 1.38e-59 219.0 COG3491@1|root,KOG0143@2759|Eukaryota 2759|Eukaryota V oxidoreductase activity - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N DYD3_k127_2334810_4 1385515.N791_12110 1.608e-49 181.0 COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1T1K1@1236|Gammaproteobacteria,1X6ZX@135614|Xanthomonadales 135614|Xanthomonadales T CBS domain - - - - - - - - - - - - CBS DYD3_k127_2334810_2 1396141.BATP01000003_gene5139 2.196e-68 236.0 COG0412@1|root,COG0412@2|Bacteria,46UHK@74201|Verrucomicrobia,2ITZ5@203494|Verrucomicrobiae 203494|Verrucomicrobiae Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH DYD3_k127_2351841_0 565045.NOR51B_286 1.991e-100 339.0 COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,1S1R2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Methylamine dehydrogenase heavy chain (MADH) mauB - 1.4.9.1 ko:K15229 ko00680,ko01120,map00680,map01120 - R00606 RC00189 ko00000,ko00001,ko01000 - - - Me-amine-dh_H DYD3_k127_2416527_1 745014.OMB55_00003860 9.122e-86 300.0 COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,1SZF1@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_2416527_0 247634.GPB2148_2037 2.156e-140 459.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1J8WE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 DYD3_k127_2426768_0 247634.GPB2148_3272 5.144e-93 327.0 COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - - - - - - - - - - Metallophos DYD3_k127_2436616_4 523791.Kkor_2503 5.918e-26 111.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1S0GX@1236|Gammaproteobacteria,1XRHB@135619|Oceanospirillales 135619|Oceanospirillales T Forkhead associated domain - - - ko:K11894 - - - - ko00000,ko02044 3.A.23.1 - - FHA DYD3_k127_2436616_2 1260251.SPISAL_05310 3.396e-37 143.0 COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1WZ3B@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF1820) - - - - - - - - - - - - DUF1820 DYD3_k127_2436616_0 1207076.ALAT01000184_gene2708 0.0 1528.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1Z29S@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 DYD3_k127_2436616_3 1121124.JNIX01000008_gene2250 1.501e-35 147.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,2UIQD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_2436616_1 765911.Thivi_3188 1.802e-159 507.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales 135613|Chromatiales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn DYD3_k127_2446884_0 519989.ECTPHS_03076 0.0 1212.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1WX68@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD3_k127_2446884_1 1535422.ND16A_1332 2.039e-69 245.0 COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,1SB70@1236|Gammaproteobacteria 1236|Gammaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) dcsG - - - - - - - - - - - GSH-S_ATP,RimK DYD3_k127_2446985_0 713586.KB900536_gene926 7.101e-319 991.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV DYD3_k127_2446985_1 396588.Tgr7_2123 3.458e-315 974.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales 135613|Chromatiales L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim DYD3_k127_2446985_3 1298865.H978DRAFT_2033 8.445e-16 79.0 COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,4690N@72275|Alteromonadaceae 1236|Gammaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S DYD3_k127_2446985_2 344747.PM8797T_20903 4.399e-40 151.0 COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes 203682|Planctomycetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate DYD3_k127_2447093_0 622637.KE124774_gene1454 2.879e-232 734.0 COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P arylsulfatase A aslA - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C DYD3_k127_2447093_1 566466.NOR53_2589 2.93e-129 420.0 COG2207@1|root,COG2207@2|Bacteria,1R73I@1224|Proteobacteria,1SYD3@1236|Gammaproteobacteria 1236|Gammaproteobacteria K AraC family transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 DYD3_k127_2455607_1 566466.NOR53_709 3.35e-16 82.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RY52@1236|Gammaproteobacteria,1J7GW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Arginase family - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD3_k127_2455607_0 666509.RCA23_c01350 3.452e-132 431.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria 28211|Alphaproteobacteria EQ N-methylhydantoinase A acetone carboxylase, beta subunit oplaH - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B DYD3_k127_2459225_1 187272.Mlg_0367 1.756e-66 227.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1WW22@135613|Chromatiales 135613|Chromatiales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind DYD3_k127_2459225_0 523791.Kkor_1789 2.433e-81 299.0 COG4969@1|root,COG4969@2|Bacteria,1N1CZ@1224|Proteobacteria,1SAKN@1236|Gammaproteobacteria,1XPU9@135619|Oceanospirillales 135619|Oceanospirillales NU Belongs to the N-Me-Phe pilin family - - - - - - - - - - - - - DYD3_k127_2459225_3 99598.Cal7507_1323 1.303e-60 216.0 COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1HK26@1161|Nostocales 1117|Cyanobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 DYD3_k127_2459225_2 1336233.JAEH01000013_gene3472 8.524e-65 240.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,2QAZ5@267890|Shewanellaceae 1236|Gammaproteobacteria E X-Pro dipeptidyl-peptidase (S15 family) - - - - - - - - - - - - Peptidase_S9 DYD3_k127_2472228_2 1381123.AYOD01000026_gene1480 4.547e-61 216.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2TRPY@28211|Alphaproteobacteria,43I8M@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Oligoendopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N DYD3_k127_2472228_0 1541065.JRFE01000001_gene2569 4.948e-131 436.0 COG0474@1|root,COG0474@2|Bacteria,1G4BB@1117|Cyanobacteria,3VM4V@52604|Pleurocapsales 1117|Cyanobacteria P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase DYD3_k127_2472228_1 1317124.DW2_02894 1.21e-104 353.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,2XNXN@285107|Thioclava 28211|Alphaproteobacteria S Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD3_k127_2472228_3 472759.Nhal_0109 1.02e-16 81.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,1RPZC@1236|Gammaproteobacteria,1WZVM@135613|Chromatiales 135613|Chromatiales J RNA-metabolising metallo-beta-lactamase - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL DYD3_k127_2473046_2 1118054.CAGW01000080_gene2753 6.12e-10 63.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,26QT5@186822|Paenibacillaceae 91061|Bacilli C SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 - - - - - - - - - - - - FAD_binding_2,Succ_DH_flav_C DYD3_k127_2473046_0 1121422.AUMW01000013_gene1423 1.746e-94 320.0 COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia,260HK@186807|Peptococcaceae 186801|Clostridia C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - 1.3.5.4 ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 DYD3_k127_2473046_1 1112214.AHIS01000088_gene874 4.011e-44 167.0 COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,2TVGC@28211|Alphaproteobacteria,2K914@204457|Sphingomonadales 204457|Sphingomonadales K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 DYD3_k127_2479330_0 396588.Tgr7_0127 5.438e-93 310.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales 135613|Chromatiales C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim DYD3_k127_2479330_1 1215092.PA6_016_00310 6.531e-86 292.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1YD2Z@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3165,iECOK1_1307.ECOK1_3701,iECS88_1305.ECS88_3669,iECUMN_1333.ECUMN_3755,iSBO_1134.SBO_3275,iUMN146_1321.UM146_16315,iUTI89_1310.UTI89_C3726 Shikimate_DH,Shikimate_dh_N DYD3_k127_2479330_2 1123253.AUBD01000002_gene1297 1.58e-70 241.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1X3RV@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD DYD3_k127_2480203_1 1122134.KB893650_gene679 8.341e-104 345.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1XI3C@135619|Oceanospirillales 135619|Oceanospirillales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N DYD3_k127_2480203_2 237609.PSAKL28_49420 1.629e-63 228.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD3_k127_2480203_0 396588.Tgr7_3279 8.154e-151 481.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1WW5T@135613|Chromatiales 135613|Chromatiales F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh DYD3_k127_2480203_3 349124.Hhal_1215 1.711e-08 55.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WW4B@135613|Chromatiales 135613|Chromatiales T response regulator glnG - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD3_k127_2490113_0 187272.Mlg_0941 2.759e-289 898.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1WW7K@135613|Chromatiales 135613|Chromatiales T GTP-binding protein TypA - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 DYD3_k127_2490113_1 580332.Slit_2348 1.011e-117 399.0 COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,44V37@713636|Nitrosomonadales 28216|Betaproteobacteria H A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response srkA - - - - - - - - - - - APH DYD3_k127_2497591_0 765910.MARPU_04010 6.458e-75 259.0 COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1X2T9@135613|Chromatiales 135613|Chromatiales J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB - - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 DYD3_k127_2497591_1 667121.ET1_03_00930 3.542e-72 251.0 COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,1RMWY@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) cmoA GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 DYD3_k127_2497591_2 1123073.KB899242_gene1160 4.98e-43 176.0 COG1876@1|root,COG1876@2|Bacteria,1N1CQ@1224|Proteobacteria,1SASN@1236|Gammaproteobacteria,1X577@135614|Xanthomonadales 135614|Xanthomonadales M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY DYD3_k127_2497591_4 1111732.AZOD01000002_gene1737 2.521e-08 56.0 2EG8N@1|root,33A0G@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_2497591_3 1286106.MPL1_06014 6.98e-15 75.0 COG0050@1|root,COG0050@2|Bacteria 2|Bacteria J translation elongation factor activity tuf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD3_k127_2503219_0 666685.R2APBS1_2644 6.638e-141 468.0 COG0758@1|root,COG0758@2|Bacteria,1N2UI@1224|Proteobacteria,1SEVM@1236|Gammaproteobacteria,1X3XH@135614|Xanthomonadales 135614|Xanthomonadales LU DNA mediated transformation - - - - - - - - - - - - - DYD3_k127_2503219_1 485918.Cpin_3622 0.0004443 53.0 COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia 976|Bacteroidetes M conserved repeat domain protein - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,SprB DYD3_k127_2514066_3 1122222.AXWR01000021_gene2302 1.058e-40 156.0 COG1167@1|root,COG1167@2|Bacteria,1WI0K@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2 DYD3_k127_2514066_4 1297742.A176_04782 1.565e-29 129.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,42U8R@68525|delta/epsilon subdivisions,2WQ0V@28221|Deltaproteobacteria 28221|Deltaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate DYD3_k127_2514066_5 1232410.KI421412_gene30 1.16e-17 92.0 298RU@1|root,2ZVW4@2|Bacteria,1NYXC@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_2514066_2 452637.Oter_2330 3.503e-42 171.0 COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae 414999|Opitutae T Signal transduction histidine kinase, LytS - - 2.7.13.3 ko:K02478 - - - - ko00000,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase DYD3_k127_2514066_1 1122137.AQXF01000003_gene1873 2.053e-42 167.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2TSPC@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg DYD3_k127_2514066_0 1120953.AUBH01000010_gene121 0.0 1062.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1QU0Y@1224|Proteobacteria,1T1KC@1236|Gammaproteobacteria,46DDA@72275|Alteromonadaceae 1236|Gammaproteobacteria HP TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_252084_1 1300345.LF41_1701 1.052e-56 202.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1X3WI@135614|Xanthomonadales 135614|Xanthomonadales C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh DYD3_k127_252084_0 1163407.UU7_10955 2.168e-101 340.0 COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,1RXYM@1236|Gammaproteobacteria,1X3GY@135614|Xanthomonadales 135614|Xanthomonadales E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase DYD3_k127_252084_2 84531.JMTZ01000115_gene2011 4.707e-43 162.0 COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,1SCUJ@1236|Gammaproteobacteria,1X6IP@135614|Xanthomonadales 135614|Xanthomonadales K MarR family transcriptional regulator - - - - - - - - - - - - MarR_2 DYD3_k127_252084_3 1217710.F969_02294 0.0002223 43.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,3NIIZ@468|Moraxellaceae 1236|Gammaproteobacteria D Reduces the stability of FtsZ polymers in the presence of ATP zapE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase DYD3_k127_2524951_0 700598.Niako_2131 3.023e-136 443.0 COG2159@1|root,COG2159@2|Bacteria,4P1VU@976|Bacteroidetes 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD3_k127_2524951_2 1209072.ALBT01000031_gene1859 1.285e-96 326.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1FG6Q@10|Cellvibrio 1236|Gammaproteobacteria K ParB-like nuclease domain parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc DYD3_k127_2524951_1 1168065.DOK_18075 5.655e-108 356.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1J5A9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D ATPases involved in chromosome partitioning parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 DYD3_k127_2533417_1 1380394.JADL01000004_gene5741 1.726e-133 428.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,2JQE0@204441|Rhodospirillales 204441|Rhodospirillales S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B DYD3_k127_2533417_0 1121104.AQXH01000001_gene1639 3.132e-178 575.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia 976|Bacteroidetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD3_k127_2533417_2 1216007.AOPM01000044_gene2844 3.484e-65 228.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,2Q185@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S Zn-dependent peptidases ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD3_k127_2564772_2 574966.KB898647_gene2462 3.412e-58 205.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XHCS@135619|Oceanospirillales 135619|Oceanospirillales C sodium proton antiporter - - - - - - - - - - - - Na_H_antiporter DYD3_k127_2564772_0 1380358.JADJ01000018_gene2548 5.007e-143 465.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E oxidoreductase - - - - - - - - - - - - DAO DYD3_k127_2564772_1 1242864.D187_002372 2.399e-84 289.0 COG4143@1|root,COG4143@2|Bacteria,1R4IE@1224|Proteobacteria,42QHK@68525|delta/epsilon subdivisions,2WUK2@28221|Deltaproteobacteria 28221|Deltaproteobacteria H (ABC) transporter - - - - - - - - - - - - - DYD3_k127_2569454_1 1042377.AFPJ01000050_gene1322 5.029e-73 246.0 COG0050@1|root,COG0050@2|Bacteria 2|Bacteria J translation elongation factor activity tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD3_k127_2569454_4 1260251.SPISAL_07480 4.702e-51 182.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1WYRW@135613|Chromatiales 135613|Chromatiales J Involved in the binding of tRNA to the ribosomes rpsJ - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 DYD3_k127_2569454_0 396588.Tgr7_2324 4.91e-91 304.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1WVZS@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 DYD3_k127_2569454_2 1177154.Y5S_03045 1.134e-72 259.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XH61@135619|Oceanospirillales 135619|Oceanospirillales J Forms part of the polypeptide exit tunnel rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 DYD3_k127_2569454_5 265072.Mfla_0281 1.088e-24 111.0 COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,2KMY0@206350|Nitrosomonadales 206350|Nitrosomonadales J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 DYD3_k127_2569454_3 106648.BBLJ01000012_gene1258 2.127e-68 240.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,3NK9Q@468|Moraxellaceae 1236|Gammaproteobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C DYD3_k127_2580499_2 247633.GP2143_09195 8.055e-57 201.0 COG3453@1|root,COG3453@2|Bacteria,1RHZ3@1224|Proteobacteria,1SH6N@1236|Gammaproteobacteria,1JBJS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Putative phosphatase (DUF442) - - - - - - - - - - - - DUF442 DYD3_k127_2580499_5 1279009.ADICEAN_02756 3.125e-07 60.0 2EJN6@1|root,33DD2@2|Bacteria,4P65G@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_2580499_1 234267.Acid_5597 1.157e-72 258.0 2FIKE@1|root,34ACF@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_2580499_3 234267.Acid_4292 3.486e-41 157.0 COG0226@1|root,COG0226@2|Bacteria,3Y8S5@57723|Acidobacteria 57723|Acidobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import - - - - - - - - - - - - - DYD3_k127_2580499_0 945713.IALB_1137 1.59e-125 423.0 COG1574@1|root,COG1574@2|Bacteria 2|Bacteria G metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 DYD3_k127_2580499_4 1278073.MYSTI_04605 9.362e-41 152.0 COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,42ZS6@68525|delta/epsilon subdivisions,2WUZM@28221|Deltaproteobacteria,2YYRA@29|Myxococcales 28221|Deltaproteobacteria F Deoxynucleoside kinase - - - - - - - - - - - - dNK DYD3_k127_2609474_5 1415780.JPOG01000001_gene812 7.306e-08 65.0 COG0457@1|root,COG0457@2|Bacteria,1N8R8@1224|Proteobacteria,1SBTP@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16 DYD3_k127_2609474_3 28229.ND2E_1191 1.741e-17 91.0 COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1THKF@1236|Gammaproteobacteria,2Q74Z@267889|Colwelliaceae 1236|Gammaproteobacteria M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl DYD3_k127_2609474_0 396588.Tgr7_0080 1.007e-300 937.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1WWI3@135613|Chromatiales 135613|Chromatiales L PFAM UvrD REP helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD3_k127_2609474_2 572477.Alvin_2079 1.667e-188 599.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1WVX7@135613|Chromatiales 135613|Chromatiales P PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N DYD3_k127_2609474_1 396588.Tgr7_0202 1.126e-194 620.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1WWUJ@135613|Chromatiales 135613|Chromatiales P Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH DYD3_k127_2609474_4 1238182.C882_3990 2.13e-12 69.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U75U@28211|Alphaproteobacteria,2JT3D@204441|Rhodospirillales 204441|Rhodospirillales Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ DYD3_k127_2611441_1 1384054.N790_05500 1.631e-63 229.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria,1X5T4@135614|Xanthomonadales 135614|Xanthomonadales EQ Peptidase family S58 - - - - - - - - - - - - Peptidase_S58 DYD3_k127_2611441_0 566466.NOR53_709 1.094e-154 503.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RY52@1236|Gammaproteobacteria,1J7GW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Arginase family - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD3_k127_2611441_2 266265.Bxe_C0004 2.082e-45 168.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,1K22A@119060|Burkholderiaceae 28216|Betaproteobacteria EQ 5-oxoprolinase - - 3.5.2.14,3.5.2.9 ko:K01469,ko:K01473 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B DYD3_k127_2622199_0 1122613.ATUP01000002_gene2643 2.186e-207 661.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U10R@28211|Alphaproteobacteria,43W4Y@69657|Hyphomonadaceae 28211|Alphaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_2622199_1 84531.JMTZ01000074_gene2093 1.169e-29 124.0 COG3386@1|root,COG3386@2|Bacteria,1RE3R@1224|Proteobacteria,1T2II@1236|Gammaproteobacteria,1XD6C@135614|Xanthomonadales 135614|Xanthomonadales G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - DYD3_k127_2626210_2 1127673.GLIP_2924 5.002e-212 670.0 2BWPY@1|root,2Z8BI@2|Bacteria,1QHHB@1224|Proteobacteria,1RP8D@1236|Gammaproteobacteria,4657P@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_2626210_1 349521.HCH_02592 2.838e-265 841.0 COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria,1XN5T@135619|Oceanospirillales 135619|Oceanospirillales E Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 DYD3_k127_2626210_3 1117647.M5M_12180 1.225e-142 465.0 28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,1J92F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_2626210_0 1049564.TevJSym_aj00060 7.359e-266 845.0 COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1J98N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 DYD3_k127_2626210_5 349521.HCH_02595 7.911e-77 265.0 COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,1S4BU@1236|Gammaproteobacteria,1XPIQ@135619|Oceanospirillales 135619|Oceanospirillales S COG3103 SH3 domain protein - - - - - - - - - - - - OMP_b-brl,SH3_3,SH3_4 DYD3_k127_2626210_6 1049564.TevJSym_aj00080 5.178e-71 246.0 COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,1JADW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl DYD3_k127_2626210_7 203122.Sde_3552 2.872e-26 109.0 2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,468BH@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4266) - - - - - - - - - - - - DUF4266 DYD3_k127_2626210_4 1049564.TevJSym_aj00110 2.686e-114 378.0 COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,1J75U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 DYD3_k127_2629715_5 1226994.AMZB01000133_gene4818 1.931e-30 128.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1YD77@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1596,iSDY_1059.SDY_0191 CTP_transf_1 DYD3_k127_2629715_3 243233.MCA0571 1.324e-88 299.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1XEM4@135618|Methylococcales 135618|Methylococcales H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD3_k127_2629715_4 1049564.TevJSym_ba00160 2.858e-75 256.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1J5ZJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF DYD3_k127_2629715_2 713586.KB900536_gene139 1.028e-100 334.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1WX9S@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD3_k127_2629715_0 396588.Tgr7_1160 7.13e-104 348.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales 135613|Chromatiales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD3_k127_2629715_1 765914.ThisiDRAFT_1080 8.3e-102 345.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1WW47@135613|Chromatiales 135613|Chromatiales J Belongs to the universal ribosomal protein uS2 family rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 DYD3_k127_2629715_6 1288826.MSNKSG1_03066 3.344e-07 55.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,46498@72275|Alteromonadaceae 1236|Gammaproteobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD3_k127_2631762_3 1384054.N790_00945 6.814e-10 60.0 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1X4JK@135614|Xanthomonadales 135614|Xanthomonadales E alanine dehydrogenase - - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N DYD3_k127_2631762_0 1123242.JH636434_gene3550 3.558e-72 258.0 COG1657@1|root,COG1657@2|Bacteria,2IX9U@203682|Planctomycetes 203682|Planctomycetes I PFAM Prenyltransferase squalene oxidase - - 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - Prenyltrans DYD3_k127_2631762_1 1095743.HMPREF1054_0309 1.604e-36 149.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y8T2@135625|Pasteurellales 135625|Pasteurellales S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 DYD3_k127_2631762_2 929562.Emtol_2535 3.022e-26 113.0 COG3595@1|root,COG3595@2|Bacteria,4NGRU@976|Bacteroidetes,47MSM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4097 DYD3_k127_2668263_8 1123253.AUBD01000005_gene224 2.703e-42 164.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales 135614|Xanthomonadales K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 DYD3_k127_2668263_3 243233.MCA2276 1.874e-73 254.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1XF2F@135618|Methylococcales 135618|Methylococcales L Phage SPO1 DNA polymerase-related protein - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD3_k127_2668263_10 396588.Tgr7_2155 2.137e-27 121.0 COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,1SH5E@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase DYD3_k127_2668263_0 1283300.ATXB01000001_gene1951 8.953e-238 747.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1XDV1@135618|Methylococcales 135618|Methylococcales J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit DYD3_k127_2668263_6 1499686.BN1079_01003 6.245e-60 213.0 COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,1S3XT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - - - - - - - - - - SLT DYD3_k127_2668263_12 1158756.AQXQ01000009_gene1043 2.932e-19 94.0 COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Acylphosphatase DYD3_k127_2668263_11 1036674.A28LD_1521 8.184e-27 113.0 COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,2QGB3@267893|Idiomarinaceae 1236|Gammaproteobacteria P arsenate reductase arsC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC DYD3_k127_2668263_4 1234364.AMSF01000086_gene2837 1.743e-71 248.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1X4PZ@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the WrbA family wrbA - 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red DYD3_k127_2668263_5 1123519.PSJM300_07225 3.346e-61 225.0 COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,1Z0AS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L Belongs to the DnaA family. HdA subfamily hda GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - ko:K10763 - - - - ko00000,ko03032 - - - Bac_DnaA DYD3_k127_2668263_2 1123401.JHYQ01000002_gene2638 1.843e-84 293.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,45ZYG@72273|Thiotrichales 72273|Thiotrichales S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD3_k127_2668263_7 768671.ThimaDRAFT_1855 3.498e-49 182.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1WY27@135613|Chromatiales 135613|Chromatiales I PFAM CDP-alcohol phosphatidyltransferase - - 2.7.8.41 ko:K08744 ko00564,ko01100,map00564,map01100 - R02030 RC00002,RC00017 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD3_k127_2668263_9 105559.Nwat_1839 7.334e-36 151.0 COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1X0ZE@135613|Chromatiales 135613|Chromatiales S Uncharacterized protein conserved in bacteria (DUF2066) - - - ko:K09938 - - - - ko00000 - - - DUF2066 DYD3_k127_2668263_1 1123368.AUIS01000006_gene648 5.311e-110 363.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,2NCJC@225057|Acidithiobacillales 225057|Acidithiobacillales F AIR synthase related protein, N-terminal domain purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD3_k127_2680610_0 1123253.AUBD01000005_gene111 2.719e-225 705.0 COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1X482@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N DYD3_k127_2680610_1 1304880.JAGB01000003_gene1291 8.115e-07 52.0 COG1274@1|root,COG1274@2|Bacteria,1TQED@1239|Firmicutes,249NP@186801|Clostridia 186801|Clostridia H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N DYD3_k127_2716551_4 765912.Thimo_3109 5.12e-19 90.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales 135613|Chromatiales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C DYD3_k127_2716551_0 1049564.TevJSym_aj00290 1.85e-185 592.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1J4RF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD3_k127_2716551_2 396588.Tgr7_0769 7.455e-111 384.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1WWB9@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 DYD3_k127_2716551_1 314278.NB231_05601 1.834e-116 392.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1WWCK@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE DYD3_k127_2716551_3 1137799.GZ78_18930 2.269e-92 314.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1XHGA@135619|Oceanospirillales 135619|Oceanospirillales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M DYD3_k127_2717014_3 697282.Mettu_0354 1.333e-84 289.0 COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Zn-dependent protease with chaperone function htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 DYD3_k127_2717014_4 697282.Mettu_0353 8.889e-78 267.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA DYD3_k127_2717014_2 396588.Tgr7_0552 3.97e-101 341.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WWAK@135613|Chromatiales 135613|Chromatiales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE DYD3_k127_2717014_6 1049564.TevJSym_aj00090 7.54e-52 189.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1J6KV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CO Thioredoxin-like resA - - - - - - - - - - - AhpC-TSA,Redoxin DYD3_k127_2717014_5 396588.Tgr7_0544 5.47e-58 208.0 2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,1S3S1@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_2717014_0 420662.Mpe_A1224 2.155e-123 417.0 COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,2VZB4@28216|Betaproteobacteria,1KN0Q@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - DYD3_k127_2717014_1 420662.Mpe_A1225 2.238e-122 413.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,2VZ4H@28216|Betaproteobacteria,1KN47@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 DYD3_k127_2723077_1 1535422.ND16A_3875 4.418e-66 235.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,2Q73E@267889|Colwelliaceae 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 DYD3_k127_2723077_0 1121878.AUGL01000006_gene753 1.601e-82 284.0 COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,1S0VJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria O cysteine protease - - - - - - - - - - - - Peptidase_C1 DYD3_k127_2731050_3 1042375.AFPL01000031_gene805 7.89e-137 443.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,463YY@72275|Alteromonadaceae 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains glnG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD3_k127_2731050_4 713586.KB900536_gene2055 9.358e-94 324.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 DYD3_k127_2731050_9 1122165.AUHS01000001_gene1302 1.648e-21 101.0 2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,1JEK9@118969|Legionellales 118969|Legionellales S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 DYD3_k127_2731050_0 713586.KB900536_gene2053 1.644e-243 759.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1WVZ2@135613|Chromatiales 135613|Chromatiales E TIGRFAM glutamine synthetase, type I glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N DYD3_k127_2731050_2 754476.Q7A_607 1.704e-158 506.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,4604S@72273|Thiotrichales 72273|Thiotrichales J glycyl-tRNA synthetase, alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e DYD3_k127_2731050_1 1121935.AQXX01000132_gene2619 2.755e-215 688.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XH7W@135619|Oceanospirillales 135619|Oceanospirillales J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f DYD3_k127_2731050_8 582744.Msip34_2129 4.203e-64 227.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,2KKR3@206350|Nitrosomonadales 206350|Nitrosomonadales I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD3_k127_2731050_5 1300345.LF41_2649 1.405e-82 297.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales 135614|Xanthomonadales T Adenylate cyclase - - - - - - - - - - - - - DYD3_k127_2731050_10 497964.CfE428DRAFT_2493 9.048e-06 57.0 COG0457@1|root,COG0457@2|Bacteria,46VI3@74201|Verrucomicrobia 74201|Verrucomicrobia S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16 DYD3_k127_2731050_7 314285.KT71_02627 2.835e-66 237.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - DYD3_k127_2731050_6 1300345.LF41_2649 2.192e-75 272.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales 135614|Xanthomonadales T Adenylate cyclase - - - - - - - - - - - - - DYD3_k127_2736738_4 1121015.N789_00840 9.944e-82 274.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1X35R@135614|Xanthomonadales 135614|Xanthomonadales EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN DYD3_k127_2736738_5 391625.PPSIR1_35137 1.04e-81 286.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales 28221|Deltaproteobacteria E Threonine dehydratase ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - ACT,PALP DYD3_k127_2736738_1 378806.STAUR_3608 4.836e-190 608.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YUCI@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer DYD3_k127_2736738_3 357808.RoseRS_1962 2.308e-129 421.0 COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,3753Z@32061|Chloroflexia 32061|Chloroflexia E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD3_k127_2736738_0 666685.R2APBS1_3653 4.166e-206 650.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1X3KZ@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase DYD3_k127_2736738_6 767434.Fraau_3197 3.034e-73 252.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,1X3N1@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C DYD3_k127_2736738_2 1385517.N800_02520 1.127e-144 469.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1X4UN@135614|Xanthomonadales 135614|Xanthomonadales CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh DYD3_k127_2736738_7 331678.Cphamn1_0820 3.564e-43 162.0 COG2021@1|root,COG2021@2|Bacteria,1FDS7@1090|Chlorobi 1090|Chlorobi E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metXA - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD3_k127_2739097_2 1049564.TevJSym_be00120 6.112e-28 116.0 COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1J6J3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Thioesterase superfamily ybgC GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790 3.1.2.23 ko:K01075,ko:K07107 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - iECP_1309.ECP_0747,iSDY_1059.SDY_0684 4HBT DYD3_k127_2739097_0 765912.Thimo_0571 1.391e-69 242.0 COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1WWA0@135613|Chromatiales 135613|Chromatiales U PFAM MotA TolQ ExbB proton channel - - - ko:K03562 ko01120,map01120 - - - ko00000,ko02000 1.A.30.2.2 - - MotA_ExbB DYD3_k127_2739097_1 1026882.MAMP_00018 6.339e-44 164.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,46135@72273|Thiotrichales 72273|Thiotrichales U Biopolymer transport protein ExbD TolR tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD DYD3_k127_2739097_3 396588.Tgr7_2230 5.185e-23 109.0 COG3064@1|root,COG3064@2|Bacteria,1R7WR@1224|Proteobacteria,1SZ86@1236|Gammaproteobacteria,1WWRY@135613|Chromatiales 135613|Chromatiales M TonB C terminal - - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 DYD3_k127_2753582_3 454957.IA64_12150 6.712e-33 134.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X2XI@135614|Xanthomonadales 135614|Xanthomonadales I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD3_k127_2753582_2 394221.Mmar10_2222 3.186e-63 222.0 COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,43XJN@69657|Hyphomonadaceae 28211|Alphaproteobacteria O Peroxiredoxin MA20_20905 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - Redoxin DYD3_k127_2753582_0 1384054.N790_05335 1.36e-136 444.0 COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,1RMK7@1236|Gammaproteobacteria,1X4RW@135614|Xanthomonadales 135614|Xanthomonadales C Electron transfer flavoprotein etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha DYD3_k127_2753582_1 1123253.AUBD01000012_gene974 9.124e-102 336.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1X34D@135614|Xanthomonadales 135614|Xanthomonadales C electron transfer flavoprotein beta subunit etfB - - ko:K03521 - - - - ko00000 - - - ETF DYD3_k127_2753582_4 926550.CLDAP_00470 2.727e-24 105.0 COG2897@1|root,COG2897@2|Bacteria,2G6J9@200795|Chloroflexi 200795|Chloroflexi P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese DYD3_k127_2755909_5 1492922.GY26_04880 6.789e-07 51.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S8D4@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Smr domain - - - - - - - - - - - - Smr DYD3_k127_2755909_3 565045.NOR51B_2685 4.82e-92 315.0 COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs truD GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD DYD3_k127_2755909_4 314278.NB231_01389 3.408e-14 76.0 COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1WZ9J@135613|Chromatiales 135613|Chromatiales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsB - - ko:K05589 - - - - ko00000,ko03036 - - - DivIC DYD3_k127_2755909_1 519989.ECTPHS_12373 4.1e-184 584.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1WVX6@135613|Chromatiales 135613|Chromatiales G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N DYD3_k127_2755909_2 1198232.CYCME_1569 2.298e-136 441.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,46088@72273|Thiotrichales 72273|Thiotrichales M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 DYD3_k127_2755909_0 713586.KB900536_gene118 8.359e-259 806.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales 135613|Chromatiales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase DYD3_k127_2763951_2 1123228.AUIH01000038_gene2751 6.125e-10 60.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1XH34@135619|Oceanospirillales 1236|Gammaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides - - - - - - - - - - - - Peptidase_M17 DYD3_k127_2763951_1 1033802.SSPSH_001221 1.989e-85 288.0 COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis rnt GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K03683 - - - - ko00000,ko01000,ko03016 - - - RNase_T DYD3_k127_2763951_0 391615.ABSJ01000026_gene133 6.579e-100 344.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J4C2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD3_k127_2774578_1 1040982.AXAL01000022_gene6445 8.711e-107 360.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,43GYK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Rieske 2Fe-2S - - - ko:K00479 - - - - ko00000 - - - Rieske,Ring_hydroxyl_A DYD3_k127_2774578_0 1121937.AUHJ01000011_gene2899 5.001e-213 677.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,4640X@72275|Alteromonadaceae 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD3_k127_2774578_2 177439.DP2354 7.444e-67 233.0 COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,42RF7@68525|delta/epsilon subdivisions,2WNMP@28221|Deltaproteobacteria,2MNFZ@213118|Desulfobacterales 28221|Deltaproteobacteria FJ MafB19-like deaminase - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 DYD3_k127_2782549_3 314287.GB2207_01817 3.164e-16 82.0 COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria,1J5M2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S A domain family that is part of the cupin metalloenzyme superfamily. ycfD GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564 1.14.11.47 ko:K18850 - - - - ko00000,ko01000,ko03009 - - - Cupin_4 DYD3_k127_2782549_1 1415780.JPOG01000001_gene1224 2.827e-181 578.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1X3E0@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 DYD3_k127_2782549_0 187272.Mlg_1359 4.791e-197 625.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1WWB4@135613|Chromatiales 135613|Chromatiales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 DYD3_k127_2782549_2 312153.Pnuc_0521 4.361e-32 132.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2VREV@28216|Betaproteobacteria,1K0I5@119060|Burkholderiaceae 28216|Betaproteobacteria L PFAM NUDIX hydrolase - - - - - - - - - - - - NUDIX DYD3_k127_2795091_0 1049564.TevJSym_ac02060 5.399e-259 811.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1J4NF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 DYD3_k127_2795091_1 472759.Nhal_0036 3.21e-104 351.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1WX02@135613|Chromatiales 135613|Chromatiales L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 DYD3_k127_2798066_0 1121875.KB907548_gene1616 1.861e-122 402.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD3_k127_2798066_1 1123368.AUIS01000019_gene1213 8.565e-70 241.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales 225057|Acidithiobacillales C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD3_k127_2798066_2 83406.HDN1F_29180 1.249e-55 201.0 COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1J8T5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase yihG - - - - - - - - - - - Acyltransferase DYD3_k127_2823365_0 296591.Bpro_0678 0.0 1140.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,4A9PE@80864|Comamonadaceae 28216|Betaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase DYD3_k127_2823365_3 338969.Rfer_3267 2.435e-67 235.0 COG0625@1|root,COG0625@2|Bacteria,1PPF9@1224|Proteobacteria,2VQQZ@28216|Betaproteobacteria 28216|Betaproteobacteria O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C_3,GST_N DYD3_k127_2823365_2 381666.H16_A1622 2.209e-71 250.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria,1K39I@119060|Burkholderiaceae 28216|Betaproteobacteria O Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD3_k127_2823365_1 326297.Sama_1484 3.559e-96 327.0 COG3137@1|root,COG3137@2|Bacteria,1RCKQ@1224|Proteobacteria,1S0GK@1236|Gammaproteobacteria,2QA2B@267890|Shewanellaceae 1236|Gammaproteobacteria M Protein of unknown function, DUF481 - - - - - - - - - - - - DUF481 DYD3_k127_2840192_5 631362.Thi970DRAFT_03022 5.846e-51 201.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1SX52@1236|Gammaproteobacteria,1X227@135613|Chromatiales 135613|Chromatiales F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C DYD3_k127_2840192_6 506534.Rhein_2118 8.324e-48 185.0 COG2503@1|root,COG2503@2|Bacteria,1RB4N@1224|Proteobacteria,1SB1V@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Acid phosphatase lppC - - - - - - - - - - - Acid_phosphat_B DYD3_k127_2840192_4 1089552.KI911559_gene1088 3.316e-154 494.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2JQ3S@204441|Rhodospirillales 204441|Rhodospirillales S Carbon-nitrogen hydrolase - - 3.5.1.6 ko:K01431 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R00905,R04666,R08228 RC00096 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase DYD3_k127_2840192_1 553385.JEMF01000039_gene2894 3.227e-230 721.0 COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,1RSR2@1236|Gammaproteobacteria,1XIA6@135619|Oceanospirillales 135619|Oceanospirillales FH cytosine purines uracil thiamine allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur DYD3_k127_2840192_0 998674.ATTE01000001_gene1577 1.395e-254 790.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,45ZQS@72273|Thiotrichales 72273|Thiotrichales F dihydroorotase - - - - - - - - - - - - Amidohydro_1 DYD3_k127_2840192_3 1122135.KB893166_gene2994 1.72e-163 531.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases preT - 1.3.1.1 ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 M00046 R00977,R01414,R11026 RC00072,RC00123 ko00000,ko00001,ko00002,ko01000 - - - Fer4_20,Pyr_redox_2 DYD3_k127_2840192_2 998674.ATTE01000001_gene1575 1.553e-218 685.0 COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,463TH@72273|Thiotrichales 72273|Thiotrichales CF Dihydroorotate dehydrogenase - - - - - - - - - - - - DHO_dh,Fer4_21 DYD3_k127_2840192_7 663932.KB902575_gene3072 2.071e-25 108.0 COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2U9FW@28211|Alphaproteobacteria,2JSQC@204441|Rhodospirillales 204441|Rhodospirillales F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis - - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1,dCMP_cyt_deam_2 DYD3_k127_284244_1 396588.Tgr7_0263 8.747e-181 579.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales 135613|Chromatiales J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d DYD3_k127_284244_0 187272.Mlg_2496 3.498e-200 647.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales 135613|Chromatiales L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII DYD3_k127_284244_2 1049564.TevJSym_am00560 1.126e-12 72.0 COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,1SA30@1236|Gammaproteobacteria,1J6NG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog rpoE1 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_28566_0 627192.SLG_25610 7.909e-92 308.0 COG4341@1|root,COG4341@2|Bacteria,1RAX5@1224|Proteobacteria,2U5RV@28211|Alphaproteobacteria,2KAD4@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD3_k127_28566_1 1280954.HPO_10095 1.007e-45 169.0 COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,2U580@28211|Alphaproteobacteria,43XNS@69657|Hyphomonadaceae 28211|Alphaproteobacteria K COG1522 Transcriptional regulators grp - - ko:K05800 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type DYD3_k127_28566_2 1207063.P24_06911 2.91e-17 85.0 2C91B@1|root,33D4Z@2|Bacteria,1N875@1224|Proteobacteria,2UFUE@28211|Alphaproteobacteria,2JXWX@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - DYD3_k127_2882240_1 1206743.BAGM01000083_gene4283 6.002e-62 217.0 COG0426@1|root,COG0426@2|Bacteria,2GKJ9@201174|Actinobacteria,4FV5C@85025|Nocardiaceae 201174|Actinobacteria C domain, Protein - - - - - - - - - - - - - DYD3_k127_2882240_0 1123073.KB899241_gene3395 3.68e-234 732.0 COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1X5K9@135614|Xanthomonadales 135614|Xanthomonadales E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD3_k127_2882240_2 1042377.AFPJ01000024_gene754 5.067e-23 98.0 COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,467KI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Anti-ECFsigma factor ChrR - - - - - - - - - - - - Cupin_7 DYD3_k127_2884170_0 1469245.JFBG01000019_gene1125 0.0 1045.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales 135613|Chromatiales J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS DYD3_k127_2884170_2 450851.PHZ_c2277 1.371e-90 308.0 COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria,2KHIG@204458|Caulobacterales 204458|Caulobacterales I PFAM alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 DYD3_k127_2884170_4 1120956.JHZK01000015_gene3022 5.24e-42 163.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2TRJ6@28211|Alphaproteobacteria,1JNY8@119043|Rhodobiaceae 28211|Alphaproteobacteria Q DSBA-like thioredoxin domain dsb - - - - - - - - - - - DSBA DYD3_k127_2884170_1 518766.Rmar_0538 1.49e-122 401.0 COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes 976|Bacteroidetes S Oxidoreductase molybdopterin binding domain - - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb DYD3_k127_2884170_3 305700.B447_08813 1.233e-55 202.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,2KW1M@206389|Rhodocyclales 206389|Rhodocyclales C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct DYD3_k127_2884170_5 1117319.PSPO_04922 1.527e-26 116.0 COG0790@1|root,COG0790@2|Bacteria,1QXJN@1224|Proteobacteria,1T3D5@1236|Gammaproteobacteria,2Q5HQ@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - - DYD3_k127_2893536_2 1453501.JELR01000002_gene376 3.3e-59 209.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,464RW@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ DYD3_k127_2893536_0 396588.Tgr7_0981 4.442e-288 897.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales 135613|Chromatiales O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 DYD3_k127_2893536_1 187272.Mlg_1974 1.862e-94 317.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1WXND@135613|Chromatiales 135613|Chromatiales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind DYD3_k127_2893536_3 1384054.N790_14860 5.468e-54 194.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1X37A@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD3_k127_2895222_1 382464.ABSI01000012_gene2201 2.725e-69 259.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C DYD3_k127_2895222_2 768671.ThimaDRAFT_2097 3.63e-42 166.0 COG2067@1|root,COG2067@2|Bacteria,1RJIQ@1224|Proteobacteria,1SAC1@1236|Gammaproteobacteria,1WZ89@135613|Chromatiales 135613|Chromatiales I long-chain fatty acid transport protein - - - - - - - - - - - - - DYD3_k127_2895222_0 1232410.KI421418_gene2245 1.289e-136 446.0 COG2911@1|root,COG2911@2|Bacteria,1QWGG@1224|Proteobacteria,43CG1@68525|delta/epsilon subdivisions,2X7R1@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of Unknown Function (DUF748) - - - - - - - - - - - - DUF748 DYD3_k127_2895222_3 118168.MC7420_198 8.01e-17 83.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,Response_reg DYD3_k127_2903869_6 290315.Clim_0520 9.437e-05 51.0 COG0679@1|root,COG0679@2|Bacteria 2|Bacteria S auxin-activated signaling pathway - - - ko:K07088 - - - - ko00000 - - - Mem_trans DYD3_k127_2903869_2 1121374.KB891585_gene2196 5.18e-92 319.0 COG0583@1|root,COG0583@2|Bacteria,1Q531@1224|Proteobacteria,1RWPD@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K16516 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD3_k127_2903869_0 1123501.KB902290_gene1553 1.374e-120 408.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD3_k127_2903869_3 627192.SLG_12640 1.236e-76 266.0 COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria,2TW4Q@28211|Alphaproteobacteria,2K9UY@204457|Sphingomonadales 204457|Sphingomonadales S KR domain - - - - - - - - - - - - adh_short DYD3_k127_2903869_4 1122612.AUBA01000015_gene880 1.694e-42 165.0 COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,2U1WS@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 DYD3_k127_2903869_1 702113.PP1Y_AT11532 1.088e-95 320.0 COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,2UPFV@28211|Alphaproteobacteria,2K9KE@204457|Sphingomonadales 204457|Sphingomonadales O Glutathione S-transferase, C-terminal domain - - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_N_3 DYD3_k127_2903869_5 1265313.HRUBRA_02132 8.775e-05 46.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Dehydrogenase - - 1.1.2.8 ko:K00114 ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130 - R05062,R05198,R05285 RC00087,RC00088,RC01039 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD3_k127_2904405_4 187272.Mlg_0341 2.368e-71 249.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria,1WWUW@135613|Chromatiales 135613|Chromatiales S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N DYD3_k127_2904405_0 572477.Alvin_2616 5.763e-179 565.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD3_k127_2904405_1 1163617.SCD_n00074 1.912e-169 540.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria 28216|Betaproteobacteria NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE DYD3_k127_2904405_2 1122604.JONR01000015_gene103 4.104e-130 424.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1X3FB@135614|Xanthomonadales 135614|Xanthomonadales NU twitching motility protein - - - - - - - - - - - - T2SSE DYD3_k127_2904405_3 765912.Thimo_2558 1.327e-87 301.0 COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,1RQ7W@1236|Gammaproteobacteria,1X286@135613|Chromatiales 135613|Chromatiales C Oxidoreductase FAD-binding domain - - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind DYD3_k127_2904405_5 75379.Tint_2548 9.513e-65 228.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,1KIWV@119065|unclassified Burkholderiales 28216|Betaproteobacteria F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD3_k127_2904841_4 243233.MCA3087 1.549e-35 146.0 COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1XEJY@135618|Methylococcales 135618|Methylococcales S Oxygen tolerance - - - - - - - - - - - - BatD DYD3_k127_2904841_0 1121918.ARWE01000001_gene2226 6.006e-132 441.0 COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria 28221|Deltaproteobacteria K von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - TPR_1,TPR_16,TPR_2,VWA,VWA_2 DYD3_k127_2904841_2 686340.Metal_0119 1.26e-108 362.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1XDQK@135618|Methylococcales 135618|Methylococcales S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA DYD3_k127_2904841_5 1121918.ARWE01000001_gene2228 1.053e-27 121.0 COG2304@1|root,COG2304@2|Bacteria,1PXSF@1224|Proteobacteria,432J9@68525|delta/epsilon subdivisions 1224|Proteobacteria S Domain of unknown function (DUF4381) - - - - - - - - - - - - DUF4381 DYD3_k127_2904841_3 243233.MCA3083 1.098e-72 260.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1XEJ0@135618|Methylococcales 135618|Methylococcales S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 DYD3_k127_2904841_1 395493.BegalDRAFT_0161 3.169e-130 424.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,45ZP7@72273|Thiotrichales 72273|Thiotrichales S associated with various cellular activities - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD3_k127_2904841_6 1131813.AQVT01000001_gene2637 8.494e-26 117.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,1JTAP@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 DYD3_k127_2913796_2 1492922.GY26_10220 3.169e-123 409.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1J4DQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N DYD3_k127_2913796_0 765910.MARPU_16735 2.292e-152 501.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales 135613|Chromatiales U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas DYD3_k127_2913796_3 713586.KB900536_gene2138 5.23e-19 94.0 COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1WYV8@135613|Chromatiales 135613|Chromatiales J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P DYD3_k127_2913796_4 349124.Hhal_1228 5.589e-15 76.0 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1WZNE@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 DYD3_k127_2913796_1 187272.Mlg_0001 1.309e-133 432.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales 135613|Chromatiales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N DYD3_k127_2976510_1 713586.KB900536_gene1839 3.488e-112 366.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1X0VD@135613|Chromatiales 135613|Chromatiales F Belongs to the dGTPase family. Type 2 subfamily - - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc DYD3_k127_2976510_0 765912.Thimo_0089 1.308e-119 394.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales 135613|Chromatiales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase DYD3_k127_3003172_2 935567.JAES01000006_gene400 5.948e-27 123.0 COG0265@1|root,COG0265@2|Bacteria,1PCJA@1224|Proteobacteria,1SXM8@1236|Gammaproteobacteria,1X6DM@135614|Xanthomonadales 135614|Xanthomonadales O PDZ domain - - - - - - - - - - - - PDZ_2 DYD3_k127_3003172_1 1283300.ATXB01000001_gene2272 5.963e-111 368.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1XDPK@135618|Methylococcales 135618|Methylococcales F Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth DYD3_k127_3003172_0 94122.Shewana3_1435 1.754e-140 452.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,2Q8RT@267890|Shewanellaceae 1236|Gammaproteobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT DYD3_k127_3010594_1 1245471.PCA10_00400 1.796e-78 274.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria,1YE3V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep DYD3_k127_3010594_0 396588.Tgr7_0331 5.609e-166 531.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales 135613|Chromatiales J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd DYD3_k127_3010594_2 1123279.ATUS01000005_gene3140 1.373e-73 256.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1J4IP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA DYD3_k127_3010594_3 1123517.JOMR01000001_gene476 4.89e-08 56.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,45ZRP@72273|Thiotrichales 72273|Thiotrichales S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 DYD3_k127_3020002_2 1122604.JONR01000014_gene218 2.156e-24 107.0 COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 DYD3_k127_3020002_0 1123073.KB899242_gene1670 6.538e-152 486.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1X3NI@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N DYD3_k127_3020002_1 1038859.AXAU01000024_gene3982 1.386e-111 363.0 COG1116@1|root,COG1116@2|Bacteria,1MU6C@1224|Proteobacteria,2TS5F@28211|Alphaproteobacteria,3JUER@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran DYD3_k127_3020002_3 1038862.KB893807_gene2161 1.752e-09 59.0 COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2U0C2@28211|Alphaproteobacteria,3JWM5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide DYD3_k127_3028282_0 627192.SLG_28740 4.105e-124 413.0 COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2U1SE@28211|Alphaproteobacteria,2K2V3@204457|Sphingomonadales 204457|Sphingomonadales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_3028282_1 1192759.AKIB01000026_gene2160 6.806e-100 333.0 COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2TSTP@28211|Alphaproteobacteria,2K8WB@204457|Sphingomonadales 204457|Sphingomonadales S KR domain - - - - - - - - - - - - adh_short DYD3_k127_303799_2 326297.Sama_2193 4.328e-38 144.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,2Q8RT@267890|Shewanellaceae 1236|Gammaproteobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475 TGT DYD3_k127_303799_3 1123401.JHYQ01000015_gene1383 1.049e-28 118.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,4613V@72273|Thiotrichales 72273|Thiotrichales U Preprotein translocase, YajC subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC DYD3_k127_303799_0 765910.MARPU_13760 6.076e-175 567.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG DYD3_k127_303799_1 1469245.JFBG01000020_gene1079 8.855e-93 315.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG DYD3_k127_3048_1 1207063.P24_12991 1.785e-97 325.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,2JPS3@204441|Rhodospirillales 204441|Rhodospirillales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD3_k127_3048_2 1532557.JL37_25285 1.788e-84 291.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2WGAR@28216|Betaproteobacteria,3T9GX@506|Alcaligenaceae 28216|Betaproteobacteria H Belongs to the HpcH HpaI aldolase family - - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI DYD3_k127_3048_4 1415779.JOMH01000001_gene2325 7.865e-71 244.0 COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,1S43F@1236|Gammaproteobacteria,1XAFN@135614|Xanthomonadales 135614|Xanthomonadales I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydratas DYD3_k127_3048_3 426355.Mrad2831_0446 7.028e-82 282.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD3_k127_3048_0 571166.KI421509_gene4104 2.722e-98 327.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2U4XB@28211|Alphaproteobacteria 28211|Alphaproteobacteria P MgtE intracellular N domain - - - - - - - - - - - - CBS,MgtE,MgtE_N DYD3_k127_3053012_3 1250005.PHEL85_0342 7.627e-30 123.0 2C7KN@1|root,32RJD@2|Bacteria,4NR1V@976|Bacteroidetes,1I42C@117743|Flavobacteriia,3VWWW@52959|Polaribacter 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_3053012_2 247639.MGP2080_00745 1.917e-53 201.0 28M5H@1|root,2ZAJ9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_3053012_1 270374.MELB17_21435 5.818e-115 382.0 COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria 1224|Proteobacteria EM Belongs to the DapA family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD3_k127_3053012_0 1453501.JELR01000002_gene1108 8.003e-179 598.0 COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,4683H@72275|Alteromonadaceae 1236|Gammaproteobacteria O Peptidase inhibitor I9 - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8 DYD3_k127_3053012_4 748247.AZKH_0917 1.932e-22 96.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,2KV9H@206389|Rhodocyclales 206389|Rhodocyclales H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas DYD3_k127_306002_6 859657.RPSI07_0652 6.163e-46 168.0 COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,1K1RC@119060|Burkholderiaceae 28216|Betaproteobacteria H Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol coq7 - - ko:K06134 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00128 R04984,R08775 RC01254 ko00000,ko00001,ko00002,ko01000 - - - COQ7 DYD3_k127_306002_4 393595.ABO_2023 4.514e-84 283.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1XH7Z@135619|Oceanospirillales 135619|Oceanospirillales K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,HTH_Crp_2,cNMP_binding DYD3_k127_306002_2 1198232.CYCME_0421 3.365e-107 352.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,46063@72273|Thiotrichales 72273|Thiotrichales G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim DYD3_k127_306002_5 1283300.ATXB01000001_gene1280 9.847e-51 189.0 COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1XEK0@135618|Methylococcales 135618|Methylococcales O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host djlA - - ko:K05801 - - - - ko00000,ko03110 - - - DnaJ,TerB DYD3_k127_306002_0 1049564.TevJSym_an00350 5.881e-128 415.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1J4E7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2476,iB21_1397.B21_02330,iBWG_1329.BWG_2240,iE2348C_1286.E2348C_2713,iEC042_1314.EC042_2677,iEC55989_1330.EC55989_2759,iECABU_c1320.ECABU_c27880,iECBD_1354.ECBD_1213,iECB_1328.ECB_02368,iECDH10B_1368.ECDH10B_2642,iECDH1ME8569_1439.ECDH1ME8569_2402,iECDH1ME8569_1439.EcDH1_1193,iECD_1391.ECD_02368,iECED1_1282.ECED1_2911,iECH74115_1262.ECH74115_3698,iECIAI1_1343.ECIAI1_2527,iECNA114_1301.ECNA114_2561,iECO103_1326.ECO103_2988,iECO111_1330.ECO111_3199,iECO26_1355.ECO26_3522,iECOK1_1307.ECOK1_2784,iECP_1309.ECP_2490,iECS88_1305.ECS88_2658,iECSE_1348.ECSE_2760,iECSF_1327.ECSF_2329,iECSP_1301.ECSP_3415,iECUMN_1333.ECUMN_2789,iECW_1372.ECW_m2698,iECs_1301.ECs3338,iEKO11_1354.EKO11_1259,iETEC_1333.ETEC_2581,iEcDH1_1363.EcDH1_1193,iEcE24377_1341.EcE24377A_2757,iEcHS_1320.EcHS_A2607,iEcSMS35_1347.EcSMS35_2623,iEcolC_1368.EcolC_1200,iG2583_1286.G2583_2999,iJN746.PP_1240,iJO1366.b2476,iJR904.b2476,iLF82_1304.LF82_1775,iNRG857_1313.NRG857_12360,iSFV_1184.SFV_2521,iSF_1195.SF2519,iSFxv_1172.SFxv_2773,iS_1188.S2669,iSbBS512_1146.SbBS512_E2848,iUMNK88_1353.UMNK88_3071,iWFL_1372.ECW_m2698,iY75_1357.Y75_RS12925,iYL1228.KPN_02810,iZ_1308.Z3735 SAICAR_synt DYD3_k127_306002_1 1122603.ATVI01000008_gene2255 5.559e-114 375.0 COG0614@1|root,COG0614@2|Bacteria,1PK1A@1224|Proteobacteria,1RRDK@1236|Gammaproteobacteria,1X3UZ@135614|Xanthomonadales 135614|Xanthomonadales P ABC transporter substrate-binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 DYD3_k127_306002_3 545276.KB898724_gene1921 2.582e-85 303.0 COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales 135613|Chromatiales K ribonuclease BN - - - ko:K07058 - - - - ko00000 - - - Rrf2,Virul_fac_BrkB DYD3_k127_3070015_2 572477.Alvin_3075 6.047e-76 257.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1WXBH@135613|Chromatiales 135613|Chromatiales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc DYD3_k127_3070015_0 1056820.KB900631_gene2323 8.967e-107 364.0 COG0400@1|root,COG0596@1|root,COG0400@2|Bacteria,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,2PND2@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 DYD3_k127_3070015_1 1163407.UU7_06813 3.606e-90 303.0 COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,1RY2V@1236|Gammaproteobacteria,1X307@135614|Xanthomonadales 135614|Xanthomonadales CP abc transporter atp-binding protein - - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran DYD3_k127_3070015_3 1384056.N787_11455 1.515e-20 95.0 COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,1RQT1@1236|Gammaproteobacteria,1X3GM@135614|Xanthomonadales 135614|Xanthomonadales CP permease natB - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,ABC2_membrane_3 DYD3_k127_307301_0 573370.DMR_01830 6.516e-154 499.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2M93H@213115|Desulfovibrionales 28221|Deltaproteobacteria I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N DYD3_k127_307301_2 1042377.AFPJ01000035_gene2624 2.391e-101 342.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RSKJ@1236|Gammaproteobacteria,46CN9@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Amino-transferase class IV ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 DYD3_k127_307301_1 1333998.M2A_2499 2.912e-110 364.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,4BRAG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 DYD3_k127_3076104_3 1292034.OR37_03048 2.88e-66 233.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2TUDX@28211|Alphaproteobacteria,2KFVR@204458|Caulobacterales 204458|Caulobacterales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_3076104_2 59538.XP_005973940.1 4.102e-83 282.0 COG2188@1|root,2SD1J@2759|Eukaryota,3ACPC@33154|Opisthokonta,3BWDP@33208|Metazoa,3DC8Y@33213|Bilateria 33208|Metazoa K UTRA - - - - - - - - - - - - GntR,UTRA DYD3_k127_3076104_1 1449076.JOOE01000002_gene987 5.971e-109 367.0 COG2222@1|root,COG2222@2|Bacteria,1MXC7@1224|Proteobacteria,2TUJY@28211|Alphaproteobacteria,2JZUW@204457|Sphingomonadales 204457|Sphingomonadales M SIS domain - - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - SIS DYD3_k127_3076104_0 1122604.JONR01000003_gene1473 2.613e-122 404.0 COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,1RMRV@1236|Gammaproteobacteria,1X36K@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 DYD3_k127_3076104_4 935567.JAES01000019_gene1061 9.223e-46 169.0 2E32R@1|root,32Y2Y@2|Bacteria,1NJNP@1224|Proteobacteria,1SQDR@1236|Gammaproteobacteria,1X847@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_307807_1 243233.MCA1747 5.203e-211 666.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XDUC@135618|Methylococcales 135618|Methylococcales F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS DYD3_k127_307807_9 1121939.L861_18525 1.432e-21 98.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XKMB@135619|Oceanospirillales 135619|Oceanospirillales K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis - - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 DYD3_k127_307807_3 1123368.AUIS01000015_gene2660 2.369e-127 415.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus DYD3_k127_307807_10 477228.YO5_02638 3.378e-07 63.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria,1Z1N5@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Protein of unknown function (DUF3426) - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 DYD3_k127_307807_5 1049564.TevJSym_cq00010 8.277e-84 293.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1J4VE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Ribosomal protein L11 methyltransferase prmA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA DYD3_k127_307807_0 1286106.MPL1_04342 1.153e-229 717.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,45ZRM@72273|Thiotrichales 72273|Thiotrichales I acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 DYD3_k127_307807_7 1255043.TVNIR_0474 6.011e-47 174.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1WY9Z@135613|Chromatiales 135613|Chromatiales I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA - - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl DYD3_k127_307807_8 335283.Neut_0845 2.295e-28 123.0 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,3732S@32003|Nitrosomonadales 28216|Betaproteobacteria CO Thioredoxin-like tlpA - - - - - - - - - - - AhpC-TSA,Redoxin DYD3_k127_307807_2 765910.MARPU_01110 1.158e-191 623.0 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales 135613|Chromatiales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 DYD3_k127_307807_6 396595.TK90_0291 1.869e-48 174.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1WYJ2@135613|Chromatiales 135613|Chromatiales O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 DYD3_k127_307807_4 395493.BegalDRAFT_0278 9.996e-111 360.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales 72273|Thiotrichales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 DYD3_k127_3078323_2 517722.AEUE01000002_gene2013 5.039e-88 293.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria,2K0BA@204457|Sphingomonadales 204457|Sphingomonadales GM Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_syn_2C,Polysacc_synt_2 DYD3_k127_3078323_6 1127695.HMPREF9163_01539 6.175e-32 141.0 COG3562@1|root,COG3562@2|Bacteria 2|Bacteria M capsule polysaccharide - - - ko:K07265 - - - - ko00000 - - - Capsule_synth DYD3_k127_3078323_5 313606.M23134_02032 6.752e-74 260.0 COG0500@1|root,COG2226@2|Bacteria,4NZH2@976|Bacteroidetes,47WDG@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 DYD3_k127_3078323_0 318161.Sden_2427 4.868e-243 784.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2Q8IQ@267890|Shewanellaceae 1236|Gammaproteobacteria P TonB-dependent receptor plug - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_3078323_3 1535422.ND16A_2018 4.954e-84 290.0 COG4424@1|root,COG4424@2|Bacteria,1R5G6@1224|Proteobacteria,1S31W@1236|Gammaproteobacteria,2Q7DE@267889|Colwelliaceae 1236|Gammaproteobacteria S Aspartyl/Asparaginyl beta-hydroxylase - - - - - - - - - - - - Asp_Arg_Hydrox,SEC-C,Sulfotransfer_3 DYD3_k127_3078323_4 318167.Sfri_0892 1.032e-80 282.0 COG4424@1|root,COG4424@2|Bacteria,1QVF4@1224|Proteobacteria,1S5MJ@1236|Gammaproteobacteria,2Q8J7@267890|Shewanellaceae 1236|Gammaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - SEC-C,Sulfotransfer_3 DYD3_k127_3078323_8 715451.ambt_09715 1.178e-09 65.0 2CMG0@1|root,32SEN@2|Bacteria,1N1PH@1224|Proteobacteria,1SA2D@1236|Gammaproteobacteria,467V8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4826) - - - - - - - - - - - - DUF4826 DYD3_k127_3078323_1 1117647.M5M_09020 4.135e-95 332.0 COG3118@1|root,COG3118@2|Bacteria,1QWQK@1224|Proteobacteria,1T5NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3 DYD3_k127_3078323_7 565045.NOR51B_247 4.206e-17 94.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 DYD3_k127_3078932_2 1415779.JOMH01000001_gene178 9.096e-43 169.0 2ASXF@1|root,31ID0@2|Bacteria,1RM30@1224|Proteobacteria,1S8I2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_3078932_0 1415778.JQMM01000001_gene1138 2.06e-96 323.0 COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria,1J4YC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG0811 Biopolymer transport proteins - - - - - - - - - - - - MotA_ExbB DYD3_k127_3078932_1 1453501.JELR01000001_gene3242 2.99e-87 295.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,46674@72275|Alteromonadaceae 1236|Gammaproteobacteria S PEGA domain - - - - - - - - - - - - FGE-sulfatase,PEGA DYD3_k127_308436_1 1122137.AQXF01000001_gene2567 2.27e-79 275.0 COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria 1224|Proteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase,DUF3471 DYD3_k127_308436_0 1122137.AQXF01000001_gene2605 5.007e-107 359.0 COG3949@1|root,COG3949@2|Bacteria,1QAYU@1224|Proteobacteria,2U6DV@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Membrane - - - - - - - - - - - - - DYD3_k127_308436_2 313606.M23134_02374 4.233e-34 132.0 COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,47K7T@768503|Cytophagia 976|Bacteroidetes M mandelate racemase muconate lactonizing - - 4.2.1.113,5.1.1.20,5.1.1.3 ko:K01776,ko:K02549,ko:K19802 ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110 M00116 R00260,R04031,R10938 RC00302,RC01053,RC03309 ko00000,ko00001,ko00002,ko01000,ko01011 - - - MR_MLE_C,MR_MLE_N DYD3_k127_3088115_4 1166948.JPZL01000003_gene502 0.0004742 44.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XJCE@135619|Oceanospirillales 135619|Oceanospirillales D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 DYD3_k127_3088115_1 395493.BegalDRAFT_1807 5.644e-56 205.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,460ST@72273|Thiotrichales 72273|Thiotrichales C PFAM cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD3_k127_3088115_3 395493.BegalDRAFT_0648 4.165e-40 161.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,460Z3@72273|Thiotrichales 72273|Thiotrichales O Thiol disulfide interchange protein - - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA DYD3_k127_3088115_2 1123261.AXDW01000003_gene1918 6.744e-49 189.0 COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,1RREZ@1236|Gammaproteobacteria,1X4WN@135614|Xanthomonadales 135614|Xanthomonadales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD DYD3_k127_3088115_0 863365.XHC_1600 2.574e-186 599.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD3_k127_3088783_4 572477.Alvin_0381 1.079e-126 412.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1WWM1@135613|Chromatiales 135613|Chromatiales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran DYD3_k127_3088783_1 1049564.TevJSym_ax00060 4.101e-160 515.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1J4TU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Domain of unknown function (DUF3333) pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 DYD3_k127_3088783_0 1049564.TevJSym_ax00050 1.854e-178 569.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1J4JR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3708 DYD3_k127_3088783_2 1411685.U062_01267 1.45e-151 486.0 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,1J5D1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG0226 ABC-type phosphate transport system, periplasmic component pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 DYD3_k127_3088783_3 396588.Tgr7_1150 4.801e-145 469.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1WWQK@135613|Chromatiales 135613|Chromatiales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 DYD3_k127_3094620_1 1123256.KB907925_gene1447 7.958e-23 114.0 COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S1WE@1236|Gammaproteobacteria,1X9QR@135614|Xanthomonadales 135614|Xanthomonadales KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD3_k127_3094620_0 1469245.JFBG01000019_gene1106 1.618e-301 939.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1WVYK@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD DYD3_k127_3102343_2 1125701.HMPREF1221_01333 2.19e-10 68.0 COG0010@1|root,COG0010@2|Bacteria,2J6IM@203691|Spirochaetes 203691|Spirochaetes E Belongs to the arginase family rocF - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD3_k127_3102343_1 195250.CM001776_gene1121 6.896e-72 254.0 COG0491@1|root,COG0491@2|Bacteria,1G400@1117|Cyanobacteria,1H175@1129|Synechococcus 1117|Cyanobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD3_k127_3102343_0 1048983.EL17_03605 2.681e-84 289.0 COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,47JWC@768503|Cytophagia 976|Bacteroidetes E Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 DYD3_k127_3107342_0 566466.NOR53_545 1.39e-145 473.0 COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,1RZG3@1236|Gammaproteobacteria,1J5K2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Protein of unknown function (DUF1298) - - - - - - - - - - - - DUF1298,WES_acyltransf DYD3_k127_3107342_3 1123504.JQKD01000006_gene1502 1.21e-62 225.0 COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2VPNT@28216|Betaproteobacteria,4ABJK@80864|Comamonadaceae 28216|Betaproteobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,PGAP1 DYD3_k127_3107342_1 1242864.D187_002927 4.467e-92 314.0 COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,42N0D@68525|delta/epsilon subdivisions,2WK3S@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin DYD3_k127_3107342_2 1120953.AUBH01000013_gene3268 7.978e-86 298.0 COG5276@1|root,COG5276@2|Bacteria,1R5D5@1224|Proteobacteria,1RMBK@1236|Gammaproteobacteria,4664J@72275|Alteromonadaceae 1236|Gammaproteobacteria S Calx-beta domain - - - - - - - - - - - - Calx-beta,LVIVD,P_proprotein DYD3_k127_3113005_1 754476.Q7A_834 2.26e-120 391.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4608Q@72273|Thiotrichales 72273|Thiotrichales E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD3_k127_3113005_4 1121374.KB891579_gene1735 1.848e-40 151.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD3_k127_3113005_3 640512.BC1003_4900 8.15e-55 218.0 COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,2WEGS@28216|Betaproteobacteria,1KHS4@119060|Burkholderiaceae 28216|Betaproteobacteria KLT Serine threonine protein kinase - - - - - - - - - - - - DUF4384,Pkinase DYD3_k127_3113005_0 743720.Psefu_4356 7.021e-153 496.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1YXC7@136845|Pseudomonas putida group 1236|Gammaproteobacteria C FAD linked oxidases, C-terminal domain - - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 DYD3_k127_3113005_2 926550.CLDAP_38230 3.122e-111 369.0 COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi 200795|Chloroflexi E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C DYD3_k127_311703_0 1279017.AQYJ01000028_gene2268 8.67e-175 568.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWTT@1224|Proteobacteria,1RP0H@1236|Gammaproteobacteria,46CKB@72275|Alteromonadaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_311703_1 1122222.AXWR01000014_gene1287 2.364e-148 488.0 COG1640@1|root,COG1640@2|Bacteria,1WJDF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G PFAM glycoside hydrolase, family 77 malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 DYD3_k127_311703_2 314275.MADE_1008400 2.151e-13 71.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,46442@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD3_k127_3119140_15 1121365.AQXB01000008_gene492 0.000877 44.0 COG0695@1|root,COG0695@2|Bacteria,2HSH3@201174|Actinobacteria,22P63@1653|Corynebacteriaceae 201174|Actinobacteria O Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - DUF836 DYD3_k127_3119140_0 765914.ThisiDRAFT_2309 7.489e-302 933.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,1WW67@135613|Chromatiales 135613|Chromatiales M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C DYD3_k127_3119140_6 713586.KB900536_gene176 2.983e-74 257.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1WXAU@135613|Chromatiales 135613|Chromatiales U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 DYD3_k127_3119140_11 1500893.JQNB01000001_gene2352 5.234e-15 81.0 COG4969@1|root,COG4969@2|Bacteria,1PJIZ@1224|Proteobacteria,1SEAV@1236|Gammaproteobacteria,1X7RT@135614|Xanthomonadales 135614|Xanthomonadales NU Domain of unknown function (DUF4845) - - - - - - - - - - - - DUF4845 DYD3_k127_3119140_7 187272.Mlg_1347 3.062e-66 232.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1WY7U@135613|Chromatiales 135613|Chromatiales J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm DYD3_k127_3119140_5 1122134.KB893651_gene2084 2.428e-94 319.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1XHGU@135619|Oceanospirillales 135619|Oceanospirillales S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 DYD3_k127_3119140_9 1469245.JFBG01000059_gene2398 5.472e-52 197.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales 135613|Chromatiales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N DYD3_k127_3119140_4 1288494.EBAPG3_14400 7.964e-96 324.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,371UI@32003|Nitrosomonadales 28216|Betaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ DYD3_k127_3119140_10 768066.HELO_3016 2.799e-25 109.0 COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria,1XKU7@135619|Oceanospirillales 135619|Oceanospirillales I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS DYD3_k127_3119140_2 519989.ECTPHS_08418 7.222e-113 369.0 COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,1S4HU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 DYD3_k127_3119140_1 767434.Fraau_1686 1.886e-129 427.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1X4IP@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA rlmD - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr DYD3_k127_3119140_3 396588.Tgr7_1754 1.772e-112 372.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1WXR0@135613|Chromatiales 135613|Chromatiales G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 DYD3_k127_3119140_8 1000565.METUNv1_01305 2.428e-63 226.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,2KV4J@206389|Rhodocyclales 206389|Rhodocyclales F Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage - - 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 DYD3_k127_3119140_12 384765.SIAM614_17017 2.341e-14 83.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TU0D@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_3,PAS_4,dCache_1 DYD3_k127_3119140_13 1198232.CYCME_1744 1.782e-12 78.0 2EC19@1|root,3360G@2|Bacteria,1PBYU@1224|Proteobacteria,1SD34@1236|Gammaproteobacteria,461FP@72273|Thiotrichales 72273|Thiotrichales S Peptidoglycan-binding protein, CsiV - - - - - - - - - - - - CsiV DYD3_k127_3119140_14 1122599.AUGR01000006_gene3698 2.563e-07 53.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XI5I@135619|Oceanospirillales 135619|Oceanospirillales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF DYD3_k127_312349_1 745411.B3C1_05622 2.37e-107 365.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1J4XV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides - - - - - - - - - - - - Peptidase_M17 DYD3_k127_312349_0 768671.ThimaDRAFT_3893 1.856e-218 685.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales 135613|Chromatiales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD3_k127_3131293_2 1123073.KB899242_gene1636 2.451e-18 89.0 COG3975@1|root,COG3975@2|Bacteria,1N69B@1224|Proteobacteria,1RY45@1236|Gammaproteobacteria,1X82A@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_3131293_0 266117.Rxyl_0145 9.383e-78 271.0 COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria 84995|Rubrobacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ DYD3_k127_3131293_1 1411685.U062_02305 5.673e-26 111.0 COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,1JA96@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1905 NADH ubiquinone oxidoreductase 24 kD subunit - - 1.6.5.3 ko:K00127,ko:K00334 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx DYD3_k127_3136577_5 215803.DB30_4242 1.176e-60 213.0 COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,434NI@68525|delta/epsilon subdivisions,2WYZV@28221|Deltaproteobacteria,2Z10X@29|Myxococcales 28221|Deltaproteobacteria E COG0346 Lactoylglutathione lyase and related lyases - - - - - - - - - - - - Glyoxalase DYD3_k127_3136577_6 685035.ADAE01000020_gene1463 1.412e-32 130.0 COG2388@1|root,COG2388@2|Bacteria,1N6YS@1224|Proteobacteria,2UG30@28211|Alphaproteobacteria 28211|Alphaproteobacteria S -acetyltransferase - - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG DYD3_k127_3136577_3 1248916.ANFY01000004_gene1772 2.087e-114 384.0 COG1228@1|root,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales 204457|Sphingomonadales QU Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,PD40 DYD3_k127_3136577_0 383381.EH30_12510 2.381e-318 1011.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria,2KEEP@204457|Sphingomonadales 204457|Sphingomonadales P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_3136577_4 565045.NOR51B_721 1.044e-109 375.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1S13F@1236|Gammaproteobacteria,1JB3R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_19,TPR_8 DYD3_k127_3136577_1 105559.Nwat_2708 1.281e-303 946.0 COG3087@1|root,COG3087@2|Bacteria,1QUVJ@1224|Proteobacteria,1RS8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - - DYD3_k127_3136577_2 713586.KB900536_gene2394 4.144e-143 463.0 COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,1WZJ8@135613|Chromatiales 135613|Chromatiales F Adenosine/AMP deaminase - - 3.5.4.2,3.5.4.4 ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01244,R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase DYD3_k127_3136577_7 1166948.JPZL01000001_gene2987 1.659e-20 93.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XICM@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD3_k127_3138771_4 1122604.JONR01000007_gene2935 1.219e-13 72.0 2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - PSCyt1 DYD3_k127_3138771_0 1122604.JONR01000007_gene2936 2.997e-96 330.0 28P4Q@1|root,2ZBZV@2|Bacteria,1RA48@1224|Proteobacteria,1S347@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_3138771_2 316067.Geob_0574 1.884e-59 219.0 COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,42TCQ@68525|delta/epsilon subdivisions,2WM2D@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM peptidase M48 Ste24p - - - - - - - - - - - - Peptidase_M48 DYD3_k127_3138771_1 1283300.ATXB01000001_gene212 1.001e-60 226.0 COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,1RY3G@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane yjgN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF898 DYD3_k127_3138771_3 765913.ThidrDRAFT_3655 3.216e-41 159.0 COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,1S2EF@1236|Gammaproteobacteria,1WY2H@135613|Chromatiales 135613|Chromatiales C Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365 DYD3_k127_3145384_1 1280953.HOC_06478 2.389e-43 161.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,43XB8@69657|Hyphomonadaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19,TPR_2,TPR_8 DYD3_k127_3145384_0 1089551.KE386572_gene2710 4.813e-100 349.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,4BSEH@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C FAD binding domain - - - - - - - - - - - - BBE,FAD_binding_4 DYD3_k127_3145384_2 566466.NOR53_1577 5.288e-42 162.0 COG0769@1|root,COG0769@2|Bacteria,1R52S@1224|Proteobacteria,1RVEK@1236|Gammaproteobacteria,1J96F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Mur ligase family, glutamate ligase domain - - - - - - - - - - - - Mur_ligase_C,Mur_ligase_M DYD3_k127_3151458_1 190650.CC_1298 1.528e-99 337.0 COG0524@1|root,COG3892@1|root,COG0524@2|Bacteria,COG3892@2|Bacteria,1MV6I@1224|Proteobacteria,2TTWN@28211|Alphaproteobacteria,2KI9M@204458|Caulobacterales 204458|Caulobacterales G Uncharacterized protein conserved in bacteria (DUF2090) - - 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DUF2090,PfkB DYD3_k127_3151458_0 1504981.KO116_3355 2.285e-168 541.0 COG3962@1|root,COG3962@2|Bacteria,1MW0P@1224|Proteobacteria,1RQ39@1236|Gammaproteobacteria,1XHSA@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the TPP enzyme family iolD - 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD3_k127_3161671_2 522373.Smlt0451 9.405e-72 243.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1X362@135614|Xanthomonadales 135614|Xanthomonadales G Dehydrogenase yliI - - - - - - - - - - - GSDH DYD3_k127_3161671_1 1415779.JOMH01000001_gene674 6.051e-76 270.0 COG3550@1|root,COG3550@2|Bacteria,1QJ5P@1224|Proteobacteria,1RP64@1236|Gammaproteobacteria,1X369@135614|Xanthomonadales 135614|Xanthomonadales S HipA-like C-terminal domain - - - - - - - - - - - - HipA_C DYD3_k127_3161671_0 1161401.ASJA01000007_gene2052 1.631e-214 679.0 COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,2U2RE@28211|Alphaproteobacteria,43X5T@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Fibronectin type 3 domain - - - - - - - - - - - - Peptidase_M28 DYD3_k127_3161671_3 396588.Tgr7_0294 2.541e-62 223.0 COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,1X0UF@135613|Chromatiales 135613|Chromatiales NU Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2,TPR_16 DYD3_k127_316764_0 243233.MCA2573 1.028e-261 820.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XEFJ@135618|Methylococcales 135618|Methylococcales L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 DYD3_k127_3173441_1 469383.Cwoe_3913 2.256e-28 121.0 COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4CSAD@84995|Rubrobacteria 84995|Rubrobacteria C FAD dependent oxidoreductase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C DYD3_k127_3173441_0 1116472.MGMO_37c00150 1.235e-222 695.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1XEUJ@135618|Methylococcales 135618|Methylococcales C Isocitrate dehydrogenase - - - - - - - - - - - - Iso_dh DYD3_k127_3182191_3 754477.Q7C_2282 0.0001562 45.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,46038@72273|Thiotrichales 72273|Thiotrichales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine - - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein DYD3_k127_3182191_1 870187.Thini_0162 1.998e-67 233.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,460IN@72273|Thiotrichales 72273|Thiotrichales F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase DYD3_k127_3182191_2 631362.Thi970DRAFT_03498 2.808e-16 87.0 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1S7FF@1236|Gammaproteobacteria,1WYCM@135613|Chromatiales 135613|Chromatiales S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 DYD3_k127_3182191_0 349966.DJ58_658 5.73e-81 275.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria,41DY3@629|Yersinia 1236|Gammaproteobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2819,iECIAI39_1322.ECIAI39_4161,iEcSMS35_1347.EcSMS35_3977,iUTI89_1310.UTI89_C4186 Pribosyltran DYD3_k127_3184767_2 84531.JMTZ01000127_gene829 2.794e-49 186.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales 135614|Xanthomonadales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase DYD3_k127_3184767_1 1283300.ATXB01000001_gene1278 1.007e-56 203.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1XEYS@135618|Methylococcales 135618|Methylococcales S Belongs to the UPF0234 family - - - ko:K09767 - - - - ko00000 - - - DUF520 DYD3_k127_3184767_0 523791.Kkor_0209 3.078e-194 624.0 COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD3_k127_3188905_2 754477.Q7C_1293 1.482e-67 243.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,460E4@72273|Thiotrichales 72273|Thiotrichales M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 DYD3_k127_3188905_1 666685.R2APBS1_2365 2.176e-77 277.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1X3DM@135614|Xanthomonadales 135614|Xanthomonadales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK DYD3_k127_3188905_0 396588.Tgr7_1371 1.051e-165 537.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1WW89@135613|Chromatiales 135613|Chromatiales V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation msbA - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran DYD3_k127_3193751_1 765910.MARPU_03585 5.488e-122 405.0 COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales 135613|Chromatiales H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH DYD3_k127_3193751_0 519989.ECTPHS_02471 6.214e-162 516.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1WXFU@135613|Chromatiales 135613|Chromatiales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD3_k127_3196505_1 671143.DAMO_1170 2.966e-43 162.0 COG1970@1|root,COG1970@2|Bacteria,2NPH6@2323|unclassified Bacteria 2|Bacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL DYD3_k127_3196505_0 1333998.M2A_1200 3.999e-167 544.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,4BQR9@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G PQQ-like domain - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 DYD3_k127_321170_2 1122137.AQXF01000002_gene426 8.152e-73 251.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2U0WI@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - - - - - - - - - - AMP-binding,AMP-binding_C DYD3_k127_321170_3 314285.KT71_05517 4.35e-70 252.0 COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,1T3KJ@1236|Gammaproteobacteria,1J91S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD3_k127_321170_1 1384054.N790_03970 9.371e-78 271.0 COG0400@1|root,COG0400@2|Bacteria,1R1F5@1224|Proteobacteria,1T50A@1236|Gammaproteobacteria,1X5JJ@135614|Xanthomonadales 135614|Xanthomonadales S Esterase PHB depolymerase - - - - - - - - - - - - Esterase_phd DYD3_k127_321170_0 1122176.KB903531_gene3098 4.019e-182 582.0 COG4145@1|root,COG4145@2|Bacteria,4PPNV@976|Bacteroidetes 976|Bacteroidetes H Sodium:solute symporter family - - - - - - - - - - - - SSF DYD3_k127_3213800_2 1121943.KB899993_gene8 1.097e-07 53.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1XK2I@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the glutaredoxin family. Monothiol subfamily ydhD - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin DYD3_k127_3213800_1 391615.ABSJ01000026_gene133 1.159e-18 96.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J4C2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg DYD3_k127_3228550_0 1122134.KB893650_gene330 7.926e-286 899.0 COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XISF@135619|Oceanospirillales 135619|Oceanospirillales M Sterol-sensing domain of SREBP cleavage-activation - - - ko:K07003 - - - - ko00000 - - - MMPL DYD3_k127_3228550_4 1278309.KB907103_gene1045 1.147e-104 346.0 COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XI25@135619|Oceanospirillales 135619|Oceanospirillales M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like DYD3_k127_3228550_2 1122134.KB893650_gene328 2.069e-150 486.0 COG4773@1|root,COG4773@2|Bacteria,1QWRF@1224|Proteobacteria,1RN9A@1236|Gammaproteobacteria,1XHTP@135619|Oceanospirillales 135619|Oceanospirillales P Receptor - - - - - - - - - - - - - DYD3_k127_3228550_5 1122194.AUHU01000004_gene1469 8.492e-23 100.0 COG0607@1|root,305JH@2|Bacteria,1QQTN@1224|Proteobacteria,1RTHA@1236|Gammaproteobacteria,468QN@72275|Alteromonadaceae 1236|Gammaproteobacteria P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 DYD3_k127_3228550_1 1121937.AUHJ01000001_gene337 6.259e-166 534.0 COG1823@1|root,COG1823@2|Bacteria,1R3F8@1224|Proteobacteria,1RMHV@1236|Gammaproteobacteria,465XI@72275|Alteromonadaceae 1236|Gammaproteobacteria U Sodium:dicarboxylate symporter family ydjN GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006791,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015184,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015811,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072348,GO:0072349,GO:0098656,GO:1901682,GO:1902475,GO:1903825,GO:1905039 - ko:K06956 - - - - ko00000 - - - SDF DYD3_k127_3228550_3 1384054.N790_01925 3.366e-113 384.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1X48I@135614|Xanthomonadales 135614|Xanthomonadales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 DYD3_k127_3232366_5 1415778.JQMM01000001_gene770 3.812e-76 264.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1J6E9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec DYD3_k127_3232366_7 305900.GV64_04910 6.687e-38 145.0 COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,1S8V6@1236|Gammaproteobacteria,1XMAY@135619|Oceanospirillales 135619|Oceanospirillales S membrane - - - - - - - - - - - - DUF962 DYD3_k127_3232366_2 1163617.SCD_n00315 3.227e-101 358.0 COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria 28216|Betaproteobacteria P phosphate-selective porin O and P - - - - - - - - - - - - - DYD3_k127_3232366_3 1163617.SCD_n00316 4.044e-95 340.0 COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria 1224|Proteobacteria P Periplasmic solute binding protein znuA - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA DYD3_k127_3232366_4 1123487.KB892846_gene512 1.289e-80 277.0 COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,2KY4A@206389|Rhodocyclales 206389|Rhodocyclales P ABC 3 transport family - - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 DYD3_k127_3232366_1 1288826.MSNKSG1_05606 1.414e-141 455.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,46489@72275|Alteromonadaceae 1236|Gammaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360 ACP_syn_III,ACP_syn_III_C DYD3_k127_3232366_0 232721.Ajs_3073 1.556e-188 608.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,4AB3C@80864|Comamonadaceae 28216|Betaproteobacteria IQ PFAM AMP-dependent synthetase and ligase - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C,Acyltransferase,PP-binding DYD3_k127_3232366_6 391615.ABSJ01000004_gene643 6.553e-40 158.0 COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1T7TI@1236|Gammaproteobacteria,1JB79@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF374) - - - - - - - - - - - - DUF374 DYD3_k127_3232366_9 743720.Psefu_1502 4.021e-05 52.0 COG3147@1|root,COG3147@2|Bacteria,1N9GW@1224|Proteobacteria,1T2CU@1236|Gammaproteobacteria,1YXXP@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 DYD3_k127_3237396_1 314278.NB231_10568 3.724e-20 91.0 COG3327@1|root,COG3327@2|Bacteria,1R4IF@1224|Proteobacteria,1RR7B@1236|Gammaproteobacteria 1236|Gammaproteobacteria K phenylacetic acid degradation operon negative regulatory protein paaX GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K02616 - - - - ko00000,ko03000 - - - PaaX,PaaX_C DYD3_k127_3237396_0 991905.SL003B_2151 2.021e-269 845.0 COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,2TUPI@28211|Alphaproteobacteria 28211|Alphaproteobacteria CI phenylacetic acid degradation protein paaN - 1.2.1.91,3.3.2.12 ko:K02618 ko00360,ko01120,map00360,map01120 - R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 - - - Aldedh,MaoC_dehydratas DYD3_k127_3240924_2 43989.cce_4306 1.42e-72 261.0 COG0277@1|root,COG0277@2|Bacteria,1GARH@1117|Cyanobacteria 1117|Cyanobacteria C D-arabinono-1,4-lactone oxidase - - - - - - - - - - - - ALO,FAD_binding_4 DYD3_k127_3240924_4 243231.GSU1575 1.336e-59 216.0 COG2890@1|root,COG2890@2|Bacteria,1RFS6@1224|Proteobacteria 1224|Proteobacteria J Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 DYD3_k127_3240924_3 935863.AWZR01000012_gene2543 1.193e-64 235.0 COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,1X433@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 DYD3_k127_3240924_1 1121930.AQXG01000001_gene1204 9.185e-86 297.0 COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 DYD3_k127_3240924_0 1121930.AQXG01000001_gene1203 2.073e-207 662.0 COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran DYD3_k127_324774_1 926561.KB900623_gene941 1.213e-71 269.0 COG1538@1|root,COG1538@2|Bacteria 2|Bacteria MU efflux transmembrane transporter activity - - - - - - - - - - - - ABC_sub_bind,OEP DYD3_k127_324774_0 1116369.KB890024_gene2927 3.583e-134 439.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,43HHC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V ABC transporter hndI GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_3249637_0 768671.ThimaDRAFT_2959 1.403e-90 304.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales 135613|Chromatiales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N DYD3_k127_3249637_3 1122201.AUAZ01000002_gene926 6.585e-37 145.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,46CRN@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family pal GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA DYD3_k127_3249637_2 472759.Nhal_0185 1.011e-45 177.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales 135613|Chromatiales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri,YfiO DYD3_k127_3249637_1 309807.SRU_0691 2.893e-78 273.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1FIND@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E homoserine dehydrogenase - - 1.1.1.3,2.7.2.4 ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3 DYD3_k127_325887_4 1121015.N789_13675 6.47e-64 224.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1X3WY@135614|Xanthomonadales 135614|Xanthomonadales M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_D23 DYD3_k127_325887_0 1121015.N789_13680 0.0 1504.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3JU@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran DYD3_k127_325887_5 1121948.AUAC01000008_gene835 3.161e-57 205.0 COG4430@1|root,COG4430@2|Bacteria,1RJGC@1224|Proteobacteria,2U3AS@28211|Alphaproteobacteria,4404V@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1801,OmdA DYD3_k127_325887_2 1163617.SCD_n02608 3.671e-160 515.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2VIZB@28216|Betaproteobacteria 28216|Betaproteobacteria C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - ko:K11102 - - - - ko00000,ko02000 2.A.23.1.1,2.A.23.1.2 - - SDF DYD3_k127_325887_3 340.xcc-b100_3376 3.157e-83 302.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,1X4BU@135614|Xanthomonadales 135614|Xanthomonadales O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 DYD3_k127_325887_7 1123034.JMKP01000021_gene2379 4.272e-14 76.0 2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,3NQBV@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_325887_6 566466.NOR53_2308 5.92e-34 132.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1J6K6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupB - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD3_k127_325887_1 713586.KB900536_gene2995 2.985e-244 760.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales 135613|Chromatiales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C DYD3_k127_326030_4 765912.Thimo_2777 1.183e-58 210.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1WWCM@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 DYD3_k127_326030_3 713586.KB900536_gene2644 1.35e-67 239.0 COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales 135613|Chromatiales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR DYD3_k127_326030_2 1333856.L686_21575 9.513e-93 319.0 COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1Z1UZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M lytic murein transglycosylase B mltB - - ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - SLT_2 DYD3_k127_326030_1 765914.ThisiDRAFT_1433 1.252e-138 450.0 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE DYD3_k127_326030_0 1026882.MAMP_00712 6.115e-194 624.0 COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales 72273|Thiotrichales M Catalyzes cross-linking of the peptidoglycan cell wall mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase DYD3_k127_326030_6 396588.Tgr7_0512 2.034e-37 147.0 COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales 135613|Chromatiales M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD DYD3_k127_326030_5 697282.Mettu_1391 1.959e-40 154.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1XECP@135618|Methylococcales 135618|Methylococcales M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC DYD3_k127_3262855_0 566466.NOR53_1577 1.549e-123 412.0 COG0769@1|root,COG0769@2|Bacteria,1R52S@1224|Proteobacteria,1RVEK@1236|Gammaproteobacteria,1J96F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Mur ligase family, glutamate ligase domain - - - - - - - - - - - - Mur_ligase_C,Mur_ligase_M DYD3_k127_3262855_1 314285.KT71_18596 3.576e-15 77.0 COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,1RS1C@1236|Gammaproteobacteria,1J57K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria HJM RimK-like ATP-grasp domain cphA - 6.3.2.29,6.3.2.30 ko:K03802 - - - - ko00000,ko01000 - - - ATP-grasp_5,CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK DYD3_k127_3263823_0 1249627.D779_1318 5.879e-170 542.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales 135613|Chromatiales L DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA rhlB - 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C DYD3_k127_3263823_1 1366050.N234_13820 7.755e-46 168.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,1K7US@119060|Burkholderiaceae 28216|Betaproteobacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD3_k127_3263823_2 1179155.CF67_18020 6.751e-34 135.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1XT0A@135623|Vibrionales 135623|Vibrionales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind DYD3_k127_3264281_1 1298593.TOL_3666 8.499e-178 566.0 COG3827@1|root,COG3827@2|Bacteria,1QQR0@1224|Proteobacteria,1S068@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_3264281_0 1121374.KB891576_gene656 0.0 1070.0 COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,1S05Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LVIVD repeat - - - - - - - - - - - - LVIVD DYD3_k127_3291106_2 316274.Haur_3390 7.184e-88 310.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2G8T7@200795|Chloroflexi,3780G@32061|Chloroflexia 200795|Chloroflexi T histidine kinase HAMP region domain protein - - - - - - - - - - - - HATPase_c,HisKA,PAS_4 DYD3_k127_3291106_0 1217718.ALOU01000041_gene56 3.621e-109 363.0 COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,1K08X@119060|Burkholderiaceae 28216|Betaproteobacteria P sulfate ABC transporter cysW - - ko:K02047 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - BPD_transp_1 DYD3_k127_3291106_1 748280.NH8B_1594 8.916e-103 341.0 COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KPDF@206351|Neisseriales 206351|Neisseriales P Sulfate ABC transporter, permease protein CysT cysT - - ko:K02046 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - BPD_transp_1 DYD3_k127_3291106_3 1110502.TMO_0705 5.045e-47 171.0 COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2TT52@28211|Alphaproteobacteria,2JQBR@204441|Rhodospirillales 204441|Rhodospirillales P Bacterial extracellular solute-binding protein sbp - - ko:K02048 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - SBP_bac_11 DYD3_k127_3296831_4 314285.KT71_02627 0.0005809 42.0 COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria,1J82F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S cAMP biosynthetic process - - - - - - - - - - - - - DYD3_k127_3296831_2 391626.OAN307_c03500 2.092e-13 78.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UBYC@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Methyltransferase - - - - - - - - - - - - PEMT DYD3_k127_3296831_3 1121878.AUGL01000021_gene2818 9.953e-08 61.0 2EUCM@1|root,33MV1@2|Bacteria,1N3HH@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_3296831_1 861299.J421_6211 5.198e-36 151.0 COG2972@1|root,COG2972@2|Bacteria,1ZUX6@142182|Gemmatimonadetes 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,His_kinase DYD3_k127_3296831_0 309807.SRU_2855 9.304e-44 169.0 COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1FJ14@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes K LytTr DNA-binding domain - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg DYD3_k127_3329187_4 761193.Runsl_0369 0.0003504 43.0 COG2866@1|root,COG2866@2|Bacteria,4NGIE@976|Bacteroidetes,47N2M@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 DYD3_k127_3329187_3 1121875.KB907556_gene570 6.625e-26 113.0 2CG01@1|root,33W86@2|Bacteria,4P395@976|Bacteroidetes,1IBKM@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_3329187_2 1300345.LF41_964 1.318e-42 161.0 COG3791@1|root,COG3791@2|Bacteria,1NC41@1224|Proteobacteria,1SCYZ@1236|Gammaproteobacteria,1XAPP@135614|Xanthomonadales 135614|Xanthomonadales S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA DYD3_k127_3329187_0 1333507.AUTQ01000230_gene2323 1.186e-86 290.0 COG2095@1|root,COG2095@2|Bacteria,1MV1C@1224|Proteobacteria,1RPM8@1236|Gammaproteobacteria,2Q22Q@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria U MarC family integral membrane protein marC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD3_k127_3329187_1 1122137.AQXF01000001_gene2740 3.311e-76 266.0 COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2U0A3@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase DYD3_k127_3333200_1 1163407.UU7_00817 1.68e-59 220.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1X527@135614|Xanthomonadales 135614|Xanthomonadales M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA DYD3_k127_3333200_0 1158756.AQXQ01000010_gene2252 1.249e-119 402.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1WW2V@135613|Chromatiales 135613|Chromatiales M zinc metalloprotease - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 DYD3_k127_3333200_2 243924.LT42_14985 1.921e-39 152.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1596,iSDY_1059.SDY_0191 CTP_transf_1 DYD3_k127_3343562_0 84531.JMTZ01000094_gene635 5.7e-68 241.0 COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,1RMKE@1236|Gammaproteobacteria,1X68I@135614|Xanthomonadales 135614|Xanthomonadales K Bacterial transcription activator, effector binding domain - - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 DYD3_k127_3343562_1 911045.PSE_2130 9.511e-53 190.0 COG3238@1|root,COG3238@2|Bacteria 2|Bacteria S Putative inner membrane exporter, YdcZ ydcZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K09936 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.7.21 - - DMT_YdcZ DYD3_k127_3343562_3 114615.BRADO6867 1.337e-30 127.0 COG3788@1|root,COG3788@2|Bacteria,1NBHH@1224|Proteobacteria,2UA0K@28211|Alphaproteobacteria,3JYVE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MAPEG family - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - MAPEG DYD3_k127_3343562_2 404589.Anae109_0029 5.125e-37 144.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,42MNS@68525|delta/epsilon subdivisions,2WSQX@28221|Deltaproteobacteria 28221|Deltaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC DYD3_k127_3350599_3 1123236.KB899379_gene1372 1.311e-10 62.0 294YR@1|root,2ZSBN@2|Bacteria,1P7I7@1224|Proteobacteria,1SUZ4@1236|Gammaproteobacteria,46C8H@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_3350599_4 1122164.JHWF01000022_gene1733 1.74e-06 51.0 2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - DYD3_k127_3350599_1 396588.Tgr7_0938 1.38e-107 362.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1WWKF@135613|Chromatiales 135613|Chromatiales O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N DYD3_k127_3350599_2 1207076.ALAT01000100_gene2593 1.803e-95 317.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1Z1PN@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease DYD3_k127_3350599_0 1027273.GZ77_05675 3.535e-219 686.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1XH3A@135619|Oceanospirillales 135619|Oceanospirillales O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX DYD3_k127_3359943_0 1279017.AQYJ01000021_gene2838 1.848e-222 702.0 COG0457@1|root,COG0457@2|Bacteria,1Q3YA@1224|Proteobacteria,1RN2D@1236|Gammaproteobacteria,46595@72275|Alteromonadaceae 1236|Gammaproteobacteria S Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 DYD3_k127_3359943_2 402881.Plav_0264 1.389e-86 297.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,1JNSR@119043|Rhodobiaceae 28211|Alphaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race DYD3_k127_3359943_3 1122604.JONR01000001_gene1749 1.109e-62 228.0 COG3832@1|root,COG4978@1|root,COG3832@2|Bacteria,COG4978@2|Bacteria,1RDMX@1224|Proteobacteria,1S914@1236|Gammaproteobacteria,1XC1N@135614|Xanthomonadales 135614|Xanthomonadales KT Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - GyrI-like,Polyketide_cyc2 DYD3_k127_3359943_1 400682.PAC_15709637 5.191e-152 491.0 COG0060@1|root,KOG0434@2759|Eukaryota,38CIS@33154|Opisthokonta,3BA51@33208|Metazoa 33208|Metazoa J isoleucyl-tRNA aminoacylation Aats-ile GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,RRM_1,tRNA-synt_1 DYD3_k127_3360208_1 335543.Sfum_1412 2.718e-80 279.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,42R10@68525|delta/epsilon subdivisions,2WN3Z@28221|Deltaproteobacteria,2MQIY@213462|Syntrophobacterales 28221|Deltaproteobacteria L NADH pyrophosphatase zinc ribbon domain nudC - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase DYD3_k127_3360208_3 518766.Rmar_1205 3.928e-64 230.0 COG3332@1|root,COG3332@2|Bacteria,4NMX4@976|Bacteroidetes,1FJ9F@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 DYD3_k127_3360208_2 1415780.JPOG01000001_gene3309 1.692e-77 265.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria,1X4YF@135614|Xanthomonadales 135614|Xanthomonadales S Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 DYD3_k127_3360208_4 370438.PTH_1200 2.81e-20 96.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,2625T@186807|Peptococcaceae 186801|Clostridia K Regulates arginine biosynthesis genes argR - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C DYD3_k127_3360208_0 378806.STAUR_5873 1.58e-116 389.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2YUQY@29|Myxococcales 28221|Deltaproteobacteria E Arginosuccinate synthase argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth DYD3_k127_3362001_1 1042377.AFPJ01000043_gene898 1.996e-108 375.0 2A6A4@1|root,30V2R@2|Bacteria,1RENE@1224|Proteobacteria,1SNHE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_3362001_5 755178.Cyan10605_3080 2.167e-07 64.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria 1117|Cyanobacteria F PFAM Tetratricopeptide repeat - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_7,TPR_8 DYD3_k127_3362001_3 1390370.O203_16470 7.054e-92 312.0 COG2010@1|root,COG2010@2|Bacteria,1N5Y7@1224|Proteobacteria,1TBQP@1236|Gammaproteobacteria,1YIJW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Planctomycete cytochrome C - - - - - - - - - - - - PSCyt1 DYD3_k127_3362001_2 1280954.HPO_07562 2.454e-101 335.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria,43ZKJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria V COG1136 ABC-type antimicrobial peptide transport system, ATPase component - - - ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - ABC_tran DYD3_k127_3362001_0 1122613.ATUP01000001_gene316 6.508e-293 922.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,43ZIX@69657|Hyphomonadaceae 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD3_k127_3362001_4 1122613.ATUP01000001_gene315 2.77e-53 197.0 COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria,43ZAU@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_3 DYD3_k127_3366486_2 522373.Smlt2756 4.157e-96 324.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1X4RI@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the glycosyl hydrolase 13 family glgX1 - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 DYD3_k127_3366486_0 561229.Dd1591_1773 2.932e-118 387.0 COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,2JCU9@204037|Dickeya 1236|Gammaproteobacteria H Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system ttcA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - ko:K14058 - - - - ko00000,ko03016 - - - ATP_bind_3 DYD3_k127_3366486_1 335283.Neut_1535 1.048e-116 382.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,372AH@32003|Nitrosomonadales 28216|Betaproteobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 DYD3_k127_3366486_5 1131553.JIBI01000047_gene1625 3.838e-14 78.0 COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,2VUK7@28216|Betaproteobacteria,3733G@32003|Nitrosomonadales 28216|Betaproteobacteria N Protein required for attachment to host cells - - - - - - - - - - - - Host_attach DYD3_k127_3366486_3 373903.Hore_22950 4.215e-81 284.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3WAFF@53433|Halanaerobiales 186801|Clostridia G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase DYD3_k127_3366486_4 1385517.N800_15095 2.156e-31 126.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1X7P3@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional - - - - - - - - - - - - HTH_5 DYD3_k127_3400219_3 643867.Ftrac_1333 3.824e-18 91.0 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47MFR@768503|Cytophagia 976|Bacteroidetes M Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD3_k127_3400219_0 1136163.M565_ctg1P1919 1.587e-156 510.0 COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1XSIH@135623|Vibrionales 135623|Vibrionales C C4-dicarboxylate anaerobic carrier - - - - - - - - - - - - Na_H_antiporter DYD3_k127_3400219_1 1472418.BBJC01000001_gene507 1.509e-41 168.0 COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria 28211|Alphaproteobacteria J translation initiation inhibitor, yjgF family - - - - - - - - - - - - YjgF_endoribonc DYD3_k127_3400219_2 1385515.N791_13130 6.283e-34 134.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1X362@135614|Xanthomonadales 135614|Xanthomonadales G Dehydrogenase yliI - - - - - - - - - - - GSDH DYD3_k127_3403338_2 395494.Galf_2013 1.275e-39 155.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1N17V@1224|Proteobacteria,2WEJE@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase cpxA - 2.7.13.3 ko:K02484,ko:K07640,ko:K07642 ko01503,ko02020,map01503,map02020 M00447,M00450,M00645,M00646,M00648,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD3_k127_3403338_1 595460.RRSWK_04882 6.314e-60 217.0 COG0631@1|root,COG0631@2|Bacteria 2|Bacteria T protein serine/threonine phosphatase activity - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 DYD3_k127_3403338_0 756272.Plabr_2883 5.252e-76 271.0 COG0515@1|root,COG0515@2|Bacteria,2J2D5@203682|Planctomycetes 203682|Planctomycetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase DYD3_k127_3434297_1 1384054.N790_13395 1.065e-101 340.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1X32N@135614|Xanthomonadales 135614|Xanthomonadales H Involved in the biosynthesis of porphyrin-containing compound - - - - - - - - - - - - HemN_C,Radical_SAM DYD3_k127_3434297_2 765912.Thimo_0079 2.149e-31 125.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,1WZ1M@135613|Chromatiales 135613|Chromatiales J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 DYD3_k127_3434297_0 187272.Mlg_2752 7.039e-191 606.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,1WWHU@135613|Chromatiales 135613|Chromatiales C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD3_k127_3435595_3 1122197.ATWI01000010_gene1194 3.001e-45 168.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,467D0@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II DYD3_k127_3435595_1 247639.MGP2080_12053 3.468e-111 368.0 COG3239@1|root,COG3239@2|Bacteria,1P79B@1224|Proteobacteria,1RNY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria I fatty acid desaturase - - - - - - - - - - - - FA_desaturase DYD3_k127_3435595_0 1121374.KB891575_gene815 3.347e-119 391.0 COG1082@1|root,COG1082@2|Bacteria,1R4JM@1224|Proteobacteria,1S5N0@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 DYD3_k127_3435595_4 1245471.PCA10_24360 9.425e-39 155.0 COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1RS5N@1236|Gammaproteobacteria,1YJ8H@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE DYD3_k127_3435595_2 1117647.M5M_06470 9.156e-53 202.0 COG3633@1|root,COG3633@2|Bacteria,1MXE1@1224|Proteobacteria,1RP9B@1236|Gammaproteobacteria,1J4YA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005295,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015175,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015804,GO:0015849,GO:0016020,GO:0016021,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032329,GO:0034220,GO:0035725,GO:0044425,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039 - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - iAF1260.b3089,iBWG_1329.BWG_2799,iECDH10B_1368.ECDH10B_3265,iECDH1ME8569_1439.ECDH1ME8569_2984,iECH74115_1262.ECH74115_4404,iECIAI1_1343.ECIAI1_3235,iECO103_1326.ECO103_3834,iECO111_1330.ECO111_3911,iECO26_1355.ECO26_4192,iECP_1309.ECP_3180,iECSE_1348.ECSE_3370,iECSP_1301.ECSP_4063,iECUMN_1333.ECUMN_3573,iECW_1372.ECW_m3356,iECs_1301.ECs3971,iEKO11_1354.EKO11_0630,iETEC_1333.ETEC_3359,iEcDH1_1363.EcDH1_0612,iEcE24377_1341.EcE24377A_3557,iG2583_1286.G2583_3813,iJO1366.b3089,iJR904.b3089,iSFV_1184.SFV_3130,iSSON_1240.SSON_3242,iUMNK88_1353.UMNK88_3845,iWFL_1372.ECW_m3356,iY75_1357.Y75_RS16050,iYL1228.KPN_03517,iZ_1308.Z4442 SDF DYD3_k127_3439721_1 1120966.AUBU01000006_gene3162 1.285e-56 203.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47NKR@768503|Cytophagia 976|Bacteroidetes E Pyridoxal-dependent decarboxylase conserved domain - - - - - - - - - - - - Pyridoxal_deC DYD3_k127_3439721_0 396588.Tgr7_0661 2.842e-84 289.0 COG0412@1|root,COG0412@2|Bacteria,1RCWF@1224|Proteobacteria,1RY38@1236|Gammaproteobacteria,1WX5X@135613|Chromatiales 135613|Chromatiales Q PFAM Dienelactone hydrolase - - - - - - - - - - - - DLH DYD3_k127_3439721_2 1280950.HJO_13121 6.735e-05 46.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C DYD3_k127_345517_2 713587.THITH_17365 4.915e-50 184.0 COG0574@1|root,COG3173@1|root,COG0574@2|Bacteria,COG3173@2|Bacteria,1Q33X@1224|Proteobacteria,1RNSN@1236|Gammaproteobacteria 1236|Gammaproteobacteria GT COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 ko:K01007,ko:K21787 ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00374,M00837,M00838 R00199,R11662,R11673 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N DYD3_k127_345517_1 1492737.FEM08_05310 1.804e-114 378.0 COG2227@1|root,COG2227@2|Bacteria,4PK4H@976|Bacteroidetes,1ID51@117743|Flavobacteriia,2NXC0@237|Flavobacterium 976|Bacteroidetes H Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 DYD3_k127_345517_3 1492737.FEM08_05320 7.987e-23 111.0 COG0204@1|root,COG0204@2|Bacteria 2|Bacteria I Acyl-transferase ypkP - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD3_k127_345517_0 713587.THITH_17355 2.88e-171 565.0 COG3173@1|root,COG3320@1|root,COG3173@2|Bacteria,COG3320@2|Bacteria 2|Bacteria Q fatty-acyl-CoA reductase (alcohol-forming) activity - - 2.1.1.179,2.7.9.2 ko:K01007,ko:K18845 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 br01600,ko00000,ko00001,ko00002,ko01000,ko01504,ko03009 - - - APH,NAD_binding_4,PP-binding DYD3_k127_3466762_1 1112217.PPL19_06796 2.209e-37 149.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria 1236|Gammaproteobacteria JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD3_k127_3466762_0 1168067.JAGP01000001_gene618 1.941e-101 341.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,45ZV5@72273|Thiotrichales 72273|Thiotrichales S PFAM Phosphotransferase enzyme family - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH DYD3_k127_3466762_2 1137799.GZ78_17130 6.758e-28 122.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1XHEA@135619|Oceanospirillales 135619|Oceanospirillales M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C DYD3_k127_3468896_4 1380346.JNIH01000014_gene844 2.074e-10 66.0 COG1231@1|root,COG1231@2|Bacteria,2GMV0@201174|Actinobacteria 201174|Actinobacteria E amine oxidase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase DYD3_k127_3468896_3 566466.NOR53_2041 7.022e-61 222.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1J62Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the bacterial glucokinase family glk GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iNRG857_1313.NRG857_12000 Glucokinase DYD3_k127_3468896_1 1385517.N800_07390 5.551e-119 392.0 COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,1RNKJ@1236|Gammaproteobacteria,1X470@135614|Xanthomonadales 135614|Xanthomonadales K LacI family - - - - - - - - - - - - LacI,Peripla_BP_3 DYD3_k127_3468896_0 318167.Sfri_1776 4.462e-208 657.0 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,1RRNW@1236|Gammaproteobacteria,2Q96J@267890|Shewanellaceae 1236|Gammaproteobacteria G PFAM major facilitator superfamily MFS_1 malT - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 DYD3_k127_3468896_2 394221.Mmar10_2740 5.541e-74 252.0 COG2819@1|root,COG2819@2|Bacteria,1QVQU@1224|Proteobacteria,2TWWU@28211|Alphaproteobacteria,43Z47@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Glycosyl-hydrolase 97 N-terminal - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Esterase,GH97_C,GH97_N,Glyco_hydro_97 DYD3_k127_3493482_6 589865.DaAHT2_0826 3.01e-10 62.0 COG0685@1|root,COG2069@1|root,COG0685@2|Bacteria,COG2069@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,2MIIA@213118|Desulfobacterales 28221|Deltaproteobacteria E PFAM Methylenetetrahydrofolate reductase - - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - CdhD,MTHFR DYD3_k127_3493482_4 655815.ZPR_4430 2.012e-38 148.0 COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1I2SS@117743|Flavobacteriia 976|Bacteroidetes O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin DYD3_k127_3493482_3 991905.SL003B_3714 4.319e-50 184.0 COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,4BQB9@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Carbon monoxide dehydrogenase subunit G coxG - - ko:K09386 - - - - ko00000 - - - COXG DYD3_k127_3493482_2 1207063.P24_04724 6.393e-74 252.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,2JS2Q@204441|Rhodospirillales 204441|Rhodospirillales C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 DYD3_k127_3493482_1 414684.RC1_1074 1.054e-94 317.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TRA8@28211|Alphaproteobacteria,2JQRH@204441|Rhodospirillales 204441|Rhodospirillales C CO dehydrogenase flavoprotein C-terminal domain - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD3_k127_3493482_0 349163.Acry_0471 6.675e-110 363.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria,2JQDG@204441|Rhodospirillales 204441|Rhodospirillales S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA,AAA_5 DYD3_k127_3493482_5 864069.MicloDRAFT_00040680 3.635e-11 64.0 COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2TSXR@28211|Alphaproteobacteria,1JTZI@119045|Methylobacteriaceae 28211|Alphaproteobacteria S VWA domain containing CoxE-like protein MA20_09405 - - ko:K07161 - - - - ko00000 - - - VWA_CoxE DYD3_k127_3506116_0 1049564.TevJSym_ah00100 4.079e-232 727.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1J5A1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the ClpA ClpB family clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD3_k127_3506116_3 396588.Tgr7_1839 2.785e-40 151.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1WYBV@135613|Chromatiales 135613|Chromatiales S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS DYD3_k127_3506116_2 1123256.KB907926_gene878 9.618e-45 175.0 COG3031@1|root,COG3031@2|Bacteria,1RD3I@1224|Proteobacteria,1RQKA@1236|Gammaproteobacteria,1X6CK@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretion system protein C - - - - - - - - - - - - PDZ_2,T2SSC DYD3_k127_3506116_1 1415780.JPOG01000001_gene1732 2.14e-45 170.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1X4RY@135614|Xanthomonadales 135614|Xanthomonadales NU secretion system protein xcsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N DYD3_k127_3519210_0 1144275.COCOR_05413 2.678e-201 643.0 COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria 1224|Proteobacteria U Peptidase m28 - - - - - - - - - - - - PA,Peptidase_M28 DYD3_k127_3519210_2 406552.NJ7G_0766 3.308e-114 386.0 COG0277@1|root,arCOG00340@2157|Archaea,2Y85H@28890|Euryarchaeota,24157@183963|Halobacteria 183963|Halobacteria C COG0277 FAD FMN-containing dehydrogenases - - - - - - - - - - - - BBE,FAD_binding_4 DYD3_k127_3519210_1 566466.NOR53_1268 3.649e-145 472.0 COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,1RQ1P@1236|Gammaproteobacteria,1J76K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E amino acid - - - - - - - - - - - - AA_permease_2 DYD3_k127_3519210_3 1122918.KB907257_gene2746 9.26e-10 63.0 COG2259@1|root,COG2259@2|Bacteria,1VCS2@1239|Firmicutes,4HKRK@91061|Bacilli,26YZ6@186822|Paenibacillaceae 91061|Bacilli S membrane catD - - - - - - - - - - - DoxX DYD3_k127_3524292_0 765914.ThisiDRAFT_1157 1.143e-150 491.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WW0R@135613|Chromatiales 135613|Chromatiales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD3_k127_3524292_2 1117647.M5M_18160 1.56e-114 385.0 28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,1JACT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_3524292_3 1056820.KB900699_gene1195 7.376e-72 254.0 28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,2PQ83@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - DYD3_k127_3524292_5 1085623.GNIT_0859 2.182e-22 98.0 2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,1SCYA@1236|Gammaproteobacteria,46BVF@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF5062) VVA0683 - - - - - - - - - - - DUF5062 DYD3_k127_3524292_4 1122604.JONR01000020_gene445 1.094e-66 233.0 COG3000@1|root,COG3000@2|Bacteria,1R4RM@1224|Proteobacteria,1SAME@1236|Gammaproteobacteria,1XA9M@135614|Xanthomonadales 135614|Xanthomonadales I sterol desaturase - - - - - - - - - - - - FA_hydroxylase DYD3_k127_3524292_1 91464.S7335_3669 7.264e-145 473.0 COG1231@1|root,COG1231@2|Bacteria,1FZVN@1117|Cyanobacteria,1H47E@1129|Synechococcus 1117|Cyanobacteria E Flavin containing amine oxidoreductase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase DYD3_k127_352892_1 1122604.JONR01000010_gene3939 2.09e-60 213.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1X6GJ@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI DYD3_k127_352892_0 713586.KB900536_gene1835 3.422e-209 672.0 COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales 135613|Chromatiales U type IV pilus secretin PilQ - - - ko:K02666 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - AMIN,STN,Secretin,Secretin_N DYD3_k127_352892_2 713586.KB900536_gene1834 6.113e-45 168.0 COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1WYAC@135613|Chromatiales 135613|Chromatiales NU pilus assembly protein PilP - - - ko:K02665 - - - - ko00000,ko02035,ko02044 - - - PilP DYD3_k127_3540560_1 1041139.KB902679_gene1971 2.122e-70 242.0 COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,2TV9C@28211|Alphaproteobacteria,4B7UD@82115|Rhizobiaceae 28211|Alphaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_1_2 DYD3_k127_3540560_0 1123366.TH3_15214 1.696e-188 595.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,2JQCF@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source acdS - 3.5.99.7 ko:K01505 ko00270,map00270 - R00997 RC00419 ko00000,ko00001,ko01000 - - - PALP DYD3_k127_3546341_4 266265.Bxe_A1664 6.097e-06 50.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,1K1GA@119060|Burkholderiaceae 28216|Betaproteobacteria S abc transporter yheS - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn DYD3_k127_3546341_0 172088.AUGA01000013_gene7373 1.73e-246 774.0 COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2UQJ2@28211|Alphaproteobacteria,3K2BQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - - - - - - - - - - HpaB,HpaB_N DYD3_k127_3546341_2 394221.Mmar10_1649 1.027e-49 181.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria,43Y20@69657|Hyphomonadaceae 28211|Alphaproteobacteria I MaoC like domain nodN - - - - - - - - - - - MaoC_dehydratas DYD3_k127_3546341_1 314285.KT71_07909 4.737e-115 377.0 COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria,1J85B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short DYD3_k127_3546341_3 1161401.ASJA01000001_gene472 1.238e-17 84.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,43WT2@69657|Hyphomonadaceae 28211|Alphaproteobacteria I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation vraB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD3_k127_3549496_1 323261.Noc_0595 2.151e-92 319.0 COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1WWFG@135613|Chromatiales 135613|Chromatiales P TIGRFAM cation diffusion facilitator family transporter - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux DYD3_k127_3549496_0 1177928.TH2_06198 1.206e-144 465.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2TTA4@28211|Alphaproteobacteria,2JQI9@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF DYD3_k127_3571314_2 1158762.KB898040_gene1360 6.057e-06 57.0 2ERTY@1|root,33JD5@2|Bacteria,1NIJV@1224|Proteobacteria,1SIGE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF4412 DYD3_k127_3571314_0 765913.ThidrDRAFT_2214 2.723e-100 339.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,1RMF8@1236|Gammaproteobacteria,1WVZR@135613|Chromatiales 135613|Chromatiales S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase DYD3_k127_3571314_1 118161.KB235922_gene5051 3.051e-39 153.0 COG1309@1|root,COG1309@2|Bacteria,1G58W@1117|Cyanobacteria,3VN4I@52604|Pleurocapsales 1117|Cyanobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_13,TetR_N DYD3_k127_3572083_1 384676.PSEEN4243 2.753e-17 89.0 COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,1S5HH@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K18301 - M00642 - - ko00000,ko00002,ko01504,ko03000 - - - TetR_C_7,TetR_N DYD3_k127_3572083_0 614083.AWQR01000022_gene106 3.989e-134 435.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2VP80@28216|Betaproteobacteria,4ADEX@80864|Comamonadaceae 28216|Betaproteobacteria S Amidohydrolase - - 4.1.1.103,4.1.1.46 ko:K07045,ko:K14333,ko:K20941 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R11353 RC00390,RC00569 ko00000,ko00001,ko01000 - - - Amidohydro_2 DYD3_k127_3572083_2 452863.Achl_3576 1.457e-11 71.0 COG2207@1|root,COG2207@2|Bacteria,2GITD@201174|Actinobacteria,1W97K@1268|Micrococcaceae 201174|Actinobacteria K Transcriptional regulator, AraC family - - - - - - - - - - - - AraC_binding_2,HTH_18 DYD3_k127_360856_13 1123393.KB891332_gene2710 5.939e-34 135.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,1KSBS@119069|Hydrogenophilales 119069|Hydrogenophilales F Ribonucleotide reductase, barrel domain - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN DYD3_k127_360856_0 1249627.D779_1787 2.273e-235 749.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales 135613|Chromatiales K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 DYD3_k127_360856_9 1123399.AQVE01000018_gene3356 3.215e-60 218.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,460HQ@72273|Thiotrichales 72273|Thiotrichales J Specifically methylates the ribose of guanosine 2251 in 23S rRNA rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind DYD3_k127_360856_10 1027273.GZ77_23790 1.583e-47 175.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1XK6B@135619|Oceanospirillales 135619|Oceanospirillales J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 DYD3_k127_360856_14 472759.Nhal_3528 3.7e-33 129.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,1WYXU@135613|Chromatiales 135613|Chromatiales J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 DYD3_k127_360856_15 2340.JV46_20540 6.916e-07 61.0 2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1RY97@1236|Gammaproteobacteria,1JBX1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S membrane - - - - - - - - - - - - DUF2232 DYD3_k127_360856_11 1279019.ARQK01000028_gene1255 5.587e-47 173.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,1WYD2@135613|Chromatiales 135613|Chromatiales J binds to the 23S rRNA rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N DYD3_k127_360856_1 472759.Nhal_3526 1.269e-186 594.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales 135613|Chromatiales L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3 DYD3_k127_360856_4 686340.Metal_2184 2.772e-102 344.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1XEEP@135618|Methylococcales 135618|Methylococcales M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N DYD3_k127_360856_8 1000565.METUNv1_02453 1.911e-63 228.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales 206389|Rhodocyclales T (FHA) domain - - - - - - - - - - - - FHA DYD3_k127_360856_6 1122604.JONR01000001_gene1978 3.688e-83 285.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1RQUV@1236|Gammaproteobacteria,1X4AA@135614|Xanthomonadales 135614|Xanthomonadales T phosphatase - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 DYD3_k127_360856_5 1000565.METUNv1_02451 2.065e-96 341.0 COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales 206389|Rhodocyclales KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - CHASE2,Pkinase DYD3_k127_360856_2 349124.Hhal_0651 5.653e-153 495.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1WWW0@135613|Chromatiales 135613|Chromatiales O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C DYD3_k127_360856_12 1033802.SSPSH_002044 8.042e-38 152.0 COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cytochrome C assembly protein ypjD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cytochrom_C_asm DYD3_k127_360856_7 396588.Tgr7_0844 3.743e-74 258.0 COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,1S453@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cAMP phosphodiesterases class-II - - - - - - - - - - - - Lactamase_B_2 DYD3_k127_360856_3 1049564.TevJSym_aa01650 2.064e-145 469.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1J4KT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB DYD3_k127_3618792_1 472759.Nhal_0597 1.611e-113 387.0 COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,1X2Q0@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K02668 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - HATPase_c,HisKA,PAS_8 DYD3_k127_3618792_0 1122603.ATVI01000009_gene2570 1.811e-158 510.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X3DA@135614|Xanthomonadales 135614|Xanthomonadales T Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains pilR - - ko:K02667 ko02020,map02020 M00501 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - HTH_8,Response_reg,Sigma54_activat DYD3_k127_3618792_2 857087.Metme_3319 5.871e-19 87.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1XFPQ@135618|Methylococcales 135618|Methylococcales U Belongs to the N-Me-Phe pilin family - - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD3_k127_3623179_5 1415780.JPOG01000001_gene1533 9.362e-32 136.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1X3BD@135614|Xanthomonadales 135614|Xanthomonadales E Transglutaminase/protease-like homologues - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core DYD3_k127_3623179_2 1122604.JONR01000025_gene4576 8.325e-66 238.0 COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,1X33K@135614|Xanthomonadales 135614|Xanthomonadales S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 DYD3_k127_3623179_1 519989.ECTPHS_05070 6.101e-108 358.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,1WXIF@135613|Chromatiales 135613|Chromatiales S associated with various cellular activities - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 DYD3_k127_3623179_0 519989.ECTPHS_04920 0.0 1276.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales 135613|Chromatiales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 DYD3_k127_3623179_4 472759.Nhal_3009 3.567e-32 132.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1WYQ1@135613|Chromatiales 135613|Chromatiales L DNA polymerase III, chi subunit - - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi DYD3_k127_3623179_3 1216966.BAUC01000022_gene1657 3.143e-34 133.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N DYD3_k127_3626066_1 105559.Nwat_2185 7.441e-111 362.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales 135613|Chromatiales M Belongs to the NAD(P)-dependent epimerase dehydratase family - - 5.1.3.2,5.1.3.5 ko:K01784,ko:K12448 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01473,R02984 RC00289,RC00528 ko00000,ko00001,ko00002,ko01000 - - - Epimerase DYD3_k127_3626066_2 1123368.AUIS01000005_gene447 3.375e-107 364.0 COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,2NBSM@225057|Acidithiobacillales 225057|Acidithiobacillales T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07711 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA DYD3_k127_3626066_0 1124991.MU9_1687 4.766e-159 512.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains yfhA GO:0000156,GO:0000160,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001130,GO:0001150,GO:0001151,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0035556,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K07715 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD3_k127_3630278_0 247633.GP2143_17871 1.193e-194 622.0 COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,1RR5H@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG0793 Periplasmic protease - - - - - - - - - - - - Peptidase_S41 DYD3_k127_3630278_3 987059.RBXJA2T_16382 1.177e-52 193.0 COG0705@1|root,COG0705@2|Bacteria,1RB4A@1224|Proteobacteria,2VMPP@28216|Betaproteobacteria 28216|Betaproteobacteria S Rhomboid family - - - - - - - - - - - - Rhomboid DYD3_k127_3630278_2 1085623.GNIT_1384 5.922e-85 291.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 DYD3_k127_3630278_1 1192034.CAP_1547 7.991e-166 535.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria,2YUQE@29|Myxococcales 28221|Deltaproteobacteria E Peptidase dimerisation domain - - 3.5.1.18 ko:K01439,ko:K13049 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD3_k127_3630278_4 1192868.CAIU01000007_gene776 2.458e-17 87.0 COG3126@1|root,COG3187@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,1N8AF@1224|Proteobacteria,2UD37@28211|Alphaproteobacteria,43IY3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Type III secretion system lipoprotein chaperone (YscW) - - - ko:K09914 - - - - ko00000 - - - META,YscW DYD3_k127_3630791_3 1286106.MPL1_05889 3.579e-60 222.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,1RMP3@1236|Gammaproteobacteria,460DU@72273|Thiotrichales 72273|Thiotrichales O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 DYD3_k127_3630791_0 1255043.TVNIR_2683 4.698e-214 674.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales 135613|Chromatiales J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey DYD3_k127_3630791_1 765914.ThisiDRAFT_1142 1.327e-206 652.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1WWC9@135613|Chromatiales 135613|Chromatiales J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD3_k127_3630791_5 1123518.ARWI01000001_gene731 1.723e-23 103.0 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales 72273|Thiotrichales H Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln DYD3_k127_3630791_2 754476.Q7A_2836 8.906e-177 559.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,4602K@72273|Thiotrichales 72273|Thiotrichales D TIGRFAM Cell shape determining protein MreB Mrl - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl DYD3_k127_3630791_4 472759.Nhal_0569 7.177e-48 178.0 COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1WWKS@135613|Chromatiales 135613|Chromatiales M Involved in formation and maintenance of cell shape - - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC DYD3_k127_3632590_0 1121374.KB891575_gene800 2.024e-135 445.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_8 DYD3_k127_3632590_2 565045.NOR51B_2035 2.038e-71 245.0 COG1917@1|root,COG1917@2|Bacteria,1N3S2@1224|Proteobacteria 1224|Proteobacteria S Aspartyl/Asparaginyl beta-hydroxylase - - - - - - - - - - - - Asp_Arg_Hydrox DYD3_k127_3632590_1 314285.KT71_03042 1.107e-89 308.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RQ1K@1236|Gammaproteobacteria,1J5KP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C PQQ-like domain - - - - - - - - - - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD3_k127_3645076_0 1121015.N789_00770 1.921e-112 372.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1X4R3@135614|Xanthomonadales 135614|Xanthomonadales E homoserine dehydrogenase thrA - 1.1.1.3,2.7.2.4 ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3 DYD3_k127_3645076_1 1123377.AUIV01000014_gene482 3.567e-58 215.0 COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,1RMYR@1236|Gammaproteobacteria,1X3BS@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD3_k127_3646494_8 1397528.Q671_12830 0.0001307 48.0 2EFUG@1|root,339KM@2|Bacteria,1NGQQ@1224|Proteobacteria,1SHZI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S (Lipo)protein oprI - - - - - - - - - - - Alanine_zipper DYD3_k127_3646494_2 1335757.SPICUR_04795 4.027e-90 309.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1WXGI@135613|Chromatiales 135613|Chromatiales M PFAM ErfK YbiS YcfS YnhG family protein - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - SPOR,YkuD DYD3_k127_3646494_3 1031711.RSPO_c03271 7.302e-71 245.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,1K2SD@119060|Burkholderiaceae 28216|Betaproteobacteria O Glutathione S-transferase gst8 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_C_3,GST_C_4,GST_N_3 DYD3_k127_3646494_5 1265503.KB905175_gene3998 1.774e-32 138.0 COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,2Q6RN@267889|Colwelliaceae 1236|Gammaproteobacteria S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 DYD3_k127_3646494_0 1123253.AUBD01000006_gene842 4.754e-136 445.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1X3CE@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C DYD3_k127_3646494_1 765914.ThisiDRAFT_0354 3.263e-108 360.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1WW6R@135613|Chromatiales 135613|Chromatiales I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis DYD3_k127_3646494_6 765913.ThidrDRAFT_0401 9.411e-23 98.0 COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria,1WZ7D@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p DYD3_k127_3646494_7 519989.ECTPHS_10376 2.3e-09 65.0 COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,1WZ3U@135613|Chromatiales 135613|Chromatiales S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 DYD3_k127_3646494_4 523791.Kkor_1182 7.762e-47 174.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1XJND@135619|Oceanospirillales 135619|Oceanospirillales D Maf-like protein maf-2 - - - - - - - - - - - Maf DYD3_k127_3655113_0 1163409.UUA_16563 1.261e-132 438.0 COG1257@1|root,COG1577@1|root,COG1257@2|Bacteria,COG1577@2|Bacteria,1MXVE@1224|Proteobacteria,1RS9R@1236|Gammaproteobacteria,1X8RF@135614|Xanthomonadales 135614|Xanthomonadales I Hydroxymethylglutaryl-coenzyme A reductase - - 1.1.1.88 ko:K00054 ko00900,ko01110,ko01130,map00900,map01110,map01130 - R02081 RC00004,RC00644 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N,HMG-CoA_red DYD3_k127_3655113_1 880073.Calab_1282 1.278e-69 241.0 COG1443@1|root,COG1443@2|Bacteria,2NQ8N@2323|unclassified Bacteria 2|Bacteria I NUDIX domain idi - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - NUDIX DYD3_k127_3655113_2 1033802.SSPSH_000812 2.221e-45 169.0 COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria 1236|Gammaproteobacteria I synthase - - 2.3.3.10 ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000,ko01008 - - - HMG_CoA_synt_C,HMG_CoA_synt_N DYD3_k127_3657931_1 1157708.KB907451_gene4655 8.736e-45 168.0 COG1011@1|root,COG1011@2|Bacteria,1RA0T@1224|Proteobacteria,2VQQ8@28216|Betaproteobacteria,4AHN0@80864|Comamonadaceae 28216|Betaproteobacteria S DinB superfamily - - - - - - - - - - - - DinB_2 DYD3_k127_3657931_0 1340493.JNIF01000003_gene1883 3.703e-94 318.0 COG1304@1|root,COG1304@2|Bacteria 2|Bacteria C FMN binding - - 1.1.3.15,1.1.3.46 ko:K00104,ko:K16422 ko00261,ko00630,ko01055,ko01100,ko01110,ko01120,ko01130,map00261,map00630,map01055,map01100,map01110,map01120,map01130 - R00475,R06633 RC00042,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh DYD3_k127_3658722_1 1535422.ND16A_2984 3.191e-82 286.0 COG1716@1|root,COG1716@2|Bacteria,1R72N@1224|Proteobacteria,1S5IZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Cytochrome c3 - - - - - - - - - - - - Cytochrom_c3_2,FHA DYD3_k127_3658722_0 1298593.TOL_3667 1.577e-186 603.0 COG3193@1|root,COG3193@2|Bacteria,1R3RC@1224|Proteobacteria,1S0DK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading DYD3_k127_366244_2 1129374.AJE_10183 6.124e-66 228.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,466U5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 DYD3_k127_366244_1 765910.MARPU_03700 2.487e-66 229.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1WWE7@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 DYD3_k127_366244_0 472759.Nhal_2382 0.0 1153.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1WW0N@135613|Chromatiales 135613|Chromatiales J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 DYD3_k127_366244_3 469610.HMPREF0189_00078 7.852e-09 57.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,1KJXX@119065|unclassified Burkholderiales 28216|Betaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 DYD3_k127_3669908_1 1117647.M5M_05965 5.392e-116 378.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria,1J8CG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_19,TPR_8 DYD3_k127_3669908_0 1121374.KB891576_gene515 2.536e-301 943.0 COG4774@1|root,COG4774@2|Bacteria,1MX2G@1224|Proteobacteria,1RYSK@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_3669908_2 502025.Hoch_4676 6.939e-47 179.0 COG1914@1|root,COG1914@2|Bacteria,1MWET@1224|Proteobacteria,42RKX@68525|delta/epsilon subdivisions,2WU57@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Mn2 and Fe2 transporters of the NRAMP family - - - - - - - - - - - - - DYD3_k127_3672120_0 754035.Mesau_04387 3.36e-141 460.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria,43NWD@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD3_k127_3693187_0 87626.PTD2_12614 4.425e-305 957.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1QU0Y@1224|Proteobacteria,1T1KC@1236|Gammaproteobacteria,2Q5GI@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_3693187_2 935863.AWZR01000007_gene200 1.334e-128 427.0 COG0457@1|root,COG3555@1|root,COG0457@2|Bacteria,COG3555@2|Bacteria,1MXZE@1224|Proteobacteria,1S1N0@1236|Gammaproteobacteria,1X5WC@135614|Xanthomonadales 135614|Xanthomonadales O beta-hydroxylase - - - - - - - - - - - - Asp_Arg_Hydrox,TPR_16,TPR_19 DYD3_k127_3693187_3 1123073.KB899242_gene1604 1.238e-63 223.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,1X7AR@135614|Xanthomonadales 135614|Xanthomonadales C Aerobic-type carbon monoxide dehydrogenase small subunit CoxS - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 DYD3_k127_3693187_1 1123073.KB899242_gene1605 2.212e-238 758.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,1X5E5@135614|Xanthomonadales 135614|Xanthomonadales C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD3_k127_3716193_2 1380394.JADL01000005_gene5457 7.969e-57 203.0 COG0665@1|root,COG0665@2|Bacteria,1R49W@1224|Proteobacteria,2TUH5@28211|Alphaproteobacteria 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO DYD3_k127_3716193_1 1033802.SSPSH_000385 2.715e-65 230.0 COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,1RQUQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0502 family yceH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09915 - - - - ko00000 - - - DUF480 DYD3_k127_3716193_3 1101195.Meth11DRAFT_2602 8.475e-30 126.0 2ARX9@1|root,31H95@2|Bacteria,1RKCT@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_3716193_0 1122176.KB903554_gene3989 4.805e-201 644.0 COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase S9, prolyl oligopeptidase, catalytic domain ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N DYD3_k127_3719592_2 697282.Mettu_1036 3.578e-25 113.0 COG0575@1|root,COG0575@2|Bacteria,1N4I3@1224|Proteobacteria,1SASF@1236|Gammaproteobacteria,1XFJZ@135618|Methylococcales 135618|Methylococcales I COG0575 CDP-diglyceride synthetase - - - - - - - - - - - - CarS-like DYD3_k127_3719592_0 1396141.BATP01000030_gene3631 3.097e-79 284.0 COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae 2|Bacteria I Phospholipase D. Active site motifs. - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD3_k127_3719592_3 319224.Sputcn32_3228 4.748e-12 73.0 2E9KN@1|root,333TE@2|Bacteria,1NCTP@1224|Proteobacteria,1SFMQ@1236|Gammaproteobacteria,2QCVA@267890|Shewanellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_3719592_1 1123228.AUIH01000001_gene1405 3.467e-38 151.0 2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,1XM11@135619|Oceanospirillales 135619|Oceanospirillales S Protein of unknown function (DUF2799) - - - - - - - - - - - - DUF2799 DYD3_k127_3719592_4 420662.Mpe_A3609 8.874e-10 69.0 2BH5I@1|root,32B6M@2|Bacteria,1RKHK@1224|Proteobacteria,2VSSI@28216|Betaproteobacteria,1KN3R@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Nuclease-related domain - - - - - - - - - - - - NERD DYD3_k127_3727556_0 472759.Nhal_0363 3.558e-168 554.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1X28I@135613|Chromatiales 135613|Chromatiales M Lysin motif - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT DYD3_k127_3727556_1 1042377.AFPJ01000030_gene479 4.184e-130 434.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA DYD3_k127_3727556_2 1123399.AQVE01000027_gene15 1.674e-78 273.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,460MK@72273|Thiotrichales 72273|Thiotrichales M Lipid A biosynthesis lpxL - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans DYD3_k127_3727556_3 42565.FP66_02765 1.124e-45 174.0 COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,1XK5R@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position kdkA - 2.7.1.166 ko:K11211 ko00540,map00540 - R09767 RC00002,RC00078 ko00000,ko00001,ko01000 - - - Kdo DYD3_k127_3732193_7 1123377.AUIV01000012_gene729 0.0001155 49.0 COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria,1SDJY@1236|Gammaproteobacteria,1X7T4@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 DYD3_k127_3732193_2 1500890.JQNL01000001_gene1301 1.53e-139 448.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1X38C@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC DYD3_k127_3732193_1 187272.Mlg_2187 3.194e-161 516.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales 135613|Chromatiales D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin DYD3_k127_3732193_0 396588.Tgr7_0774 3.338e-213 667.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales 135613|Chromatiales D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA DYD3_k127_3732193_6 1429851.X548_01630 1.144e-38 156.0 COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1X5H6@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 DYD3_k127_3732193_4 1121013.P873_03170 1.315e-93 319.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1X46K@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N DYD3_k127_3732193_3 187272.Mlg_2191 6.472e-101 339.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales 135613|Chromatiales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C DYD3_k127_3732193_5 1304275.C41B8_04701 4.087e-42 157.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the MurCDEF family murC GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iECP_1309.ECP_0093 Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD3_k127_3735062_0 472759.Nhal_0500 0.0 1077.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales 135613|Chromatiales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW DYD3_k127_3735062_8 391008.Smal_0612 1.289e-29 126.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1X3N9@135614|Xanthomonadales 135614|Xanthomonadales HL Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,NUDIX_4,TMP-TENI DYD3_k127_3735062_4 1049564.TevJSym_bd00120 4.531e-59 214.0 COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,1JAAI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity zapD GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044424,GO:0044444,GO:0044464,GO:0051301 - ko:K18778 - - - - ko00000,ko03036 - - - ZapD DYD3_k127_3735062_5 1120970.AUBZ01000004_gene295 9.745e-50 185.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,466TA@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE DYD3_k127_3735062_3 1026882.MAMP_01430 4.516e-109 360.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,460AW@72273|Thiotrichales 72273|Thiotrichales NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 DYD3_k127_3735062_2 686340.Metal_2508 2.893e-163 523.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1XE3Q@135618|Methylococcales 135618|Methylococcales U PFAM Type II secretion system F domain pilC - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF DYD3_k127_3735062_1 765914.ThisiDRAFT_1281 2.041e-228 721.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales 135613|Chromatiales NU TIGRFAM type IV-A pilus assembly ATPase PilB - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N DYD3_k127_3735062_6 1121921.KB898706_gene2722 1.439e-36 145.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2PNZB@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria NU Pilin (bacterial filament) pilA - - ko:K02650,ko:K02655 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD3_k127_3735062_7 1123261.AXDW01000007_gene2363 1.629e-34 136.0 COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,1X7J5@135614|Xanthomonadales 135614|Xanthomonadales NU Belongs to the N-Me-Phe pilin family pilA - - ko:K02650 ko02020,map02020 - - - ko00000,ko00001,ko02035,ko02044 3.A.15.2 - - N_methyl,Pilin DYD3_k127_3735392_0 1411685.U062_02135 8.065e-83 288.0 COG3712@1|root,COG3712@2|Bacteria,1QFP6@1224|Proteobacteria,1RZAU@1236|Gammaproteobacteria 1236|Gammaproteobacteria PT Fe2 -dicitrate sensor, membrane component - - - ko:K07165 - - - - ko00000 - - - DUF4880,DUF4974,FecR DYD3_k127_3735392_1 1411685.U062_02136 3.965e-19 94.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1RNZX@1236|Gammaproteobacteria 1236|Gammaproteobacteria P receptor viuA - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_3752411_2 1232410.KI421421_gene3631 8.924e-78 272.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,42MNS@68525|delta/epsilon subdivisions,2WSQX@28221|Deltaproteobacteria 28221|Deltaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC DYD3_k127_3752411_1 1454004.AW11_01567 1.007e-83 302.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria 28216|Betaproteobacteria S aldo keto reductase - - - - - - - - - - - - Aldo_ket_red DYD3_k127_3752411_5 472759.Nhal_3016 2.512e-34 136.0 COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1WYQZ@135613|Chromatiales 135613|Chromatiales S pfam rdd - - - - - - - - - - - - RDD DYD3_k127_3752411_4 1286106.MPL1_04942 1.124e-54 209.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,460N2@72273|Thiotrichales 72273|Thiotrichales S Permease YjgP YjgQ lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ DYD3_k127_3752411_3 1122604.JONR01000001_gene1930 5.153e-75 265.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1X46N@135614|Xanthomonadales 135614|Xanthomonadales S permease - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ DYD3_k127_3752411_0 266265.Bxe_A3638 1.422e-149 489.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,1K141@119060|Burkholderiaceae 28216|Betaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N DYD3_k127_3752411_6 1283300.ATXB01000001_gene1028 2.415e-07 58.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1XH00@135618|Methylococcales 135618|Methylococcales L DNA polymerase III chi subunit, HolC - - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi DYD3_k127_3779075_3 1504672.669786994 0.0005907 48.0 COG0494@1|root,COG0494@2|Bacteria,1NTFG@1224|Proteobacteria,2VMFZ@28216|Betaproteobacteria,4ACYZ@80864|Comamonadaceae 28216|Betaproteobacteria L PFAM NUDIX hydrolase - - - - - - - - - - - - - DYD3_k127_3779075_1 366602.Caul_4877 1.88e-40 156.0 COG3832@1|root,COG3832@2|Bacteria,1N2PR@1224|Proteobacteria,2VGJB@28211|Alphaproteobacteria,2KJ19@204458|Caulobacterales 204458|Caulobacterales S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 DYD3_k127_3779075_0 935567.JAES01000008_gene2007 1.468e-94 317.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RTDE@1236|Gammaproteobacteria,1X5AI@135614|Xanthomonadales 135614|Xanthomonadales K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form cobB - - - - - - - - - - - SIR2 DYD3_k127_3779075_2 243090.RB2364 3.05e-28 122.0 COG0705@1|root,COG0705@2|Bacteria 2|Bacteria S proteolysis - - - - - - - - - - - - Rhomboid DYD3_k127_3786998_3 1122609.AUGT01000012_gene4354 8.238e-20 103.0 COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4DNTB@85009|Propionibacteriales 201174|Actinobacteria E Indole-3-glycerol phosphate synthase trpC GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS DYD3_k127_3786998_1 682795.AciX8_0620 7.483e-70 258.0 COG0547@1|root,COG0547@2|Bacteria,3Y3YF@57723|Acidobacteria,2JIGH@204432|Acidobacteriia 204432|Acidobacteriia E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 DYD3_k127_3786998_2 429009.Adeg_1161 1.235e-66 240.0 COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,42G1H@68295|Thermoanaerobacterales 186801|Clostridia EH TIGRFAM glutamine amidotransferase of anthranilate synthase trpG - 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase DYD3_k127_3786998_0 398767.Glov_2547 2.04e-120 403.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43TZF@69541|Desulfuromonadales 28221|Deltaproteobacteria H Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657,ko:K13503 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind DYD3_k127_3786998_4 1122134.KB893650_gene196 3.467e-16 78.0 COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD3_k127_3815650_2 748247.AZKH_1499 2.592e-41 160.0 COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,2KVK9@206389|Rhodocyclales 206389|Rhodocyclales IQ Phosphate acyltransferases - - - - - - - - - - - - AMP-binding,Acyltransferase,PP-binding DYD3_k127_3815650_0 1453501.JELR01000001_gene3061 1.713e-150 498.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464E8@72275|Alteromonadaceae 1236|Gammaproteobacteria I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iJN746.PP_2215 Thiolase_C,Thiolase_N DYD3_k127_3815650_1 935567.JAES01000003_gene293 7.368e-93 314.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1X30J@135614|Xanthomonadales 135614|Xanthomonadales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short,adh_short_C2 DYD3_k127_3818527_2 1123401.JHYQ01000031_gene3379 6.262e-86 292.0 2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,1S2KN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S EcsC protein family - - - - - - - - - - - - EcsC DYD3_k127_3818527_1 405948.SACE_6720 1.233e-102 359.0 COG3540@1|root,COG3540@2|Bacteria,2GJCI@201174|Actinobacteria,4DZX4@85010|Pseudonocardiales 201174|Actinobacteria P phosphatase phoD - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N DYD3_k127_3818527_0 69395.JQLZ01000008_gene2456 5.357e-162 536.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria 1224|Proteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,STN,TonB_dep_Rec DYD3_k127_3837541_0 243233.MCA1990 4.206e-250 781.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1XDYW@135618|Methylococcales 135618|Methylococcales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C DYD3_k127_3837541_1 314278.NB231_15358 9.679e-114 380.0 COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,1S03J@1236|Gammaproteobacteria,1WYH5@135613|Chromatiales 135613|Chromatiales S Major facilitator superfamily - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 DYD3_k127_3849759_0 1288494.EBAPG3_2310 1.137e-185 595.0 COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,3743Q@32003|Nitrosomonadales 28216|Betaproteobacteria O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF DYD3_k127_3849759_1 1049564.TevJSym_al00340 2.143e-142 461.0 COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,1RQBE@1236|Gammaproteobacteria,1JA5R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O AIR synthase related protein, N-terminal domain hypE GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C DYD3_k127_3849759_2 1122604.JONR01000009_gene2463 8.096e-92 316.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1X9CN@135614|Xanthomonadales 135614|Xanthomonadales S AAA domain - - - - - - - - - - - - AAA_33,APH DYD3_k127_38511_1 1292034.OR37_03050 1.18e-174 574.0 COG1080@1|root,COG2190@1|root,COG1080@2|Bacteria,COG2190@2|Bacteria,1MUT8@1224|Proteobacteria,2TR28@28211|Alphaproteobacteria,2KIAS@204458|Caulobacterales 204458|Caulobacterales G PTS system, glucose subfamily, IIA - - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_1 DYD3_k127_38511_0 509190.Cseg_3140 3.435e-192 616.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1MY1V@1224|Proteobacteria,2U1WG@28211|Alphaproteobacteria,2KHNX@204458|Caulobacterales 204458|Caulobacterales G PTS system, N-acetylglucosamine-specific - - 2.7.1.193 ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 M00267 R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 - - PTS_EIIB,PTS_EIIC DYD3_k127_38511_3 1207075.PputUW4_02088 1.527e-155 496.0 COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,1RSNG@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Cupin_6,HTH_18 DYD3_k127_38511_2 1301098.PKB_4281 3.233e-159 506.0 2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - AurF DYD3_k127_38511_4 1268068.PG5_60330 7.547e-58 206.0 2BW4Q@1|root,32QZ0@2|Bacteria,1N1UX@1224|Proteobacteria,1SAJ0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MAPEG family - - - - - - - - - - - - MAPEG DYD3_k127_385751_1 1238450.VIBNISOn1_1160108 2.637e-74 256.0 COG1396@1|root,COG1396@2|Bacteria,1R3Z8@1224|Proteobacteria,1RRMV@1236|Gammaproteobacteria,1XVVD@135623|Vibrionales 135623|Vibrionales K Protein of unknown function (DUF3612) - - - - - - - - - - - - DUF3612,HTH_3,Peptidase_M78 DYD3_k127_385751_0 658187.LDG_6212 3.674e-200 631.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1JDF8@118969|Legionellales 118969|Legionellales C Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - ICL DYD3_k127_385751_2 935567.JAES01000035_gene2338 1.307e-18 90.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1X3M4@135614|Xanthomonadales 135614|Xanthomonadales F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK DYD3_k127_3918615_0 1382356.JQMP01000001_gene1193 1.186e-66 249.0 COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia 189775|Thermomicrobia S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD3_k127_3918615_1 204669.Acid345_1270 4.675e-57 201.0 COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia 204432|Acidobacteriia Q Flavin containing amine oxidoreductase - - - - - - - - - - - - NAD_binding_8 DYD3_k127_3923225_0 1380394.JADL01000002_gene1789 1.28e-242 770.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TQSC@28211|Alphaproteobacteria,2JREM@204441|Rhodospirillales 204441|Rhodospirillales L UvrD/REP helicase N-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C DYD3_k127_3923225_4 29581.BW37_01808 2.632e-71 251.0 COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,47249@75682|Oxalobacteraceae 28216|Betaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD3_k127_3923225_1 153948.NAL212_1200 7.411e-228 734.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2VP0G@28216|Betaproteobacteria 28216|Betaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C DYD3_k127_3923225_2 93220.LV28_08380 9.137e-116 388.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2VH3Z@28216|Betaproteobacteria,1K0ZE@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM Alcohol dehydrogenase zinc-binding domain protein qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N DYD3_k127_3923225_3 1280944.HY17_12995 4.072e-91 308.0 COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria,43XDJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 DYD3_k127_3923225_5 911045.PSE_0031 5.078e-71 248.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Pyridine nucleotide-disulphide oxidoreductase thcD - 1.14.13.111,1.18.1.3 ko:K00529,ko:K16968 ko00071,ko00360,ko00920,ko01120,ko01220,map00071,map00360,map00920,map01120,map01220 M00545 R02000,R06782,R06783,R09513 RC00098,RC02556 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C DYD3_k127_3948017_1 1523503.JPMY01000003_gene4197 9.878e-82 277.0 COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,1RNY2@1236|Gammaproteobacteria 1236|Gammaproteobacteria K response regulator kdpE - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD3_k127_3948017_0 1430440.MGMSRv2_1827 7.205e-103 352.0 COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,2JPB0@204441|Rhodospirillales 204441|Rhodospirillales T Histidine kinase kdpD - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp DYD3_k127_3948017_2 349521.HCH_00025 5.669e-08 59.0 COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,1RMN6@1236|Gammaproteobacteria,1XHSI@135619|Oceanospirillales 135619|Oceanospirillales P Trk system potassium uptake protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH DYD3_k127_3948521_1 1396858.Q666_10645 7.336e-121 392.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4645B@72275|Alteromonadaceae 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB DYD3_k127_3948521_0 1260251.SPISAL_03465 4.57e-151 488.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1WX6R@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class I and II - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD3_k127_395088_7 215803.DB30_4561 1.024e-19 92.0 COG0451@1|root,COG0451@2|Bacteria,1RBSM@1224|Proteobacteria,42XUG@68525|delta/epsilon subdivisions,2WTSY@28221|Deltaproteobacteria,2YX8Q@29|Myxococcales 28221|Deltaproteobacteria GM NAD dependent epimerase/dehydratase family - - 1.3.1.45 ko:K05281 ko00943,ko01110,map00943,map01110 - R06562,R06563,R07747,R07751 RC00805 ko00000,ko00001,ko01000 - - - Epimerase DYD3_k127_395088_5 1379270.AUXF01000003_gene3543 2.055e-143 467.0 COG1013@1|root,COG1013@2|Bacteria,1ZSWT@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C DYD3_k127_395088_2 1280953.HOC_18124 5.202e-258 807.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,43Z43@69657|Hyphomonadaceae 28211|Alphaproteobacteria C pyruvate flavodoxin ferredoxin oxidoreductase MA20_01045 - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N DYD3_k127_395088_1 1280949.HAD_14109 7.122e-289 896.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases MA20_01050 - 1.17.1.10 ko:K15022 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 M00377 R00134 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2,Pyr_redox_3 DYD3_k127_395088_4 1122604.JONR01000020_gene512 1.605e-174 560.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,1X34T@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 DYD3_k127_395088_6 1005048.CFU_0135 1.043e-135 439.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2VIEF@28216|Betaproteobacteria,4727I@75682|Oxalobacteraceae 28216|Betaproteobacteria E Belongs to the peptidase S33 family pip GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 DYD3_k127_395088_0 518766.Rmar_0089 0.0 1105.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Peptidase M16 - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C DYD3_k127_395088_3 240292.Ava_0676 6.456e-211 666.0 COG1171@1|root,COG1171@2|Bacteria,1G22X@1117|Cyanobacteria,1HJWD@1161|Nostocales 1117|Cyanobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iJN678.ilvA PALP,Thr_dehydrat_C DYD3_k127_3951520_3 204669.Acid345_2285 1.016e-77 274.0 COG0491@1|root,COG0491@2|Bacteria,3Y3UW@57723|Acidobacteria,2JK4T@204432|Acidobacteriia 204432|Acidobacteriia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD3_k127_3951520_4 1430440.MGMSRv2_1523 1.127e-34 143.0 COG0589@1|root,COG0589@2|Bacteria,1RCG7@1224|Proteobacteria,2U6TI@28211|Alphaproteobacteria,2JSIM@204441|Rhodospirillales 204441|Rhodospirillales T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp DYD3_k127_3951520_1 1469245.JFBG01000023_gene1275 1.307e-134 441.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales 135613|Chromatiales M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS DYD3_k127_3951520_2 1469245.JFBG01000023_gene1276 2.889e-124 414.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_3 DYD3_k127_3951520_0 1479238.JQMZ01000001_gene2125 1.549e-144 467.0 2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,2TTDU@28211|Alphaproteobacteria,43WQ2@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2891) - - - - - - - - - - - - DUF2891 DYD3_k127_3951520_5 338963.Pcar_0118 2.613e-07 61.0 COG3568@1|root,COG3568@2|Bacteria,1RA4I@1224|Proteobacteria 1224|Proteobacteria L deoxyribonuclease I - - - - - - - - - - - - Ada_Zn_binding,Exo_endo_phos,HHH_3,LTD DYD3_k127_3964052_1 314285.KT71_06242 7.994e-51 193.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1J5SG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_3964052_2 1173028.ANKO01000041_gene3226 5.282e-31 135.0 COG2085@1|root,COG2085@2|Bacteria,1G8DX@1117|Cyanobacteria,1HHG6@1150|Oscillatoriales 1117|Cyanobacteria S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD3_k127_3964052_0 84531.JMTZ01000005_gene2412 1.301e-58 214.0 COG2220@1|root,COG2220@2|Bacteria 2|Bacteria S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - - - - - - - - - - Lactamase_B_2 DYD3_k127_3964052_3 1463895.JODA01000011_gene6750 1.415e-28 119.0 COG0583@1|root,COG0583@2|Bacteria,2IB4W@201174|Actinobacteria 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD3_k127_3965686_0 743721.Psesu_1697 0.0 1208.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C DYD3_k127_3965686_2 1123279.ATUS01000001_gene1443 3.397e-112 375.0 COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,1J4BZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF2333 DYD3_k127_3965686_7 194439.CT0704 4.784e-42 165.0 COG1451@1|root,COG1451@2|Bacteria,1FE2Z@1090|Chlorobi 1090|Chlorobi S WLM domain - - - ko:K07043 - - - - ko00000 - - - DUF45 DYD3_k127_3965686_8 935863.AWZR01000001_gene1626 6.413e-30 129.0 COG3595@1|root,COG3595@2|Bacteria,1N10U@1224|Proteobacteria,1S8T2@1236|Gammaproteobacteria,1X5XN@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_3965686_4 1123228.AUIH01000001_gene1239 3.203e-103 346.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1XHSS@135619|Oceanospirillales 135619|Oceanospirillales V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_3965686_3 1123399.AQVE01000001_gene691 8.038e-109 361.0 COG0842@1|root,COG0842@2|Bacteria,1QTBE@1224|Proteobacteria,1RNG9@1236|Gammaproteobacteria,461U3@72273|Thiotrichales 72273|Thiotrichales V ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane DYD3_k127_3965686_5 1442599.JAAN01000046_gene2710 4.16e-91 306.0 COG0084@1|root,COG0084@2|Bacteria,1MXN8@1224|Proteobacteria,1RNCC@1236|Gammaproteobacteria,1X3N8@135614|Xanthomonadales 135614|Xanthomonadales L Preprotein translocase subunit TatD tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase DYD3_k127_3965686_9 765912.Thimo_2257 2.022e-17 91.0 COG0551@1|root,COG0551@2|Bacteria,1PZFI@1224|Proteobacteria,1RQ64@1236|Gammaproteobacteria,1WXVE@135613|Chromatiales 135613|Chromatiales L NERD domain protein - - - - - - - - - - - - NERD,zf-C4_Topoisom DYD3_k127_3965686_1 743721.Psesu_1251 4.958e-134 440.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1RQ0H@1236|Gammaproteobacteria,1X541@135614|Xanthomonadales 135614|Xanthomonadales E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N DYD3_k127_3965686_6 1123377.AUIV01000014_gene482 1.163e-65 236.0 COG0083@1|root,COG0083@2|Bacteria,1MW8I@1224|Proteobacteria,1RMYR@1236|Gammaproteobacteria,1X3BS@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N DYD3_k127_3968083_1 566466.NOR53_2937 1.73e-84 298.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RPG7@1236|Gammaproteobacteria,1J8F1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ AMP-binding enzyme C-terminal domain - - - - - - - - - - - - AMP-binding,AMP-binding_C DYD3_k127_3968083_3 47839.CCAU010000019_gene3427 1.352e-25 123.0 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,236JX@1762|Mycobacteriaceae 201174|Actinobacteria IQ AMP-binding enzyme - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C DYD3_k127_3968083_2 1479238.JQMZ01000001_gene1961 2.113e-67 235.0 COG1309@1|root,COG1309@2|Bacteria,1R6X5@1224|Proteobacteria,2U7EK@28211|Alphaproteobacteria,43XKJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_N DYD3_k127_3968083_0 883126.HMPREF9710_04085 1.1e-224 720.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2WGP9@28216|Betaproteobacteria,476ZS@75682|Oxalobacteraceae 28216|Betaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_3968083_4 1248232.BANQ01000145_gene3505 4.013e-15 90.0 COG2911@1|root,COG2911@2|Bacteria,1QJJV@1224|Proteobacteria,1THKA@1236|Gammaproteobacteria,1XWHS@135623|Vibrionales 135623|Vibrionales S Dicarboxylate transport - - - - - - - - - - - - DctA-YdbH DYD3_k127_4001754_1 1265313.HRUBRA_02768 2.485e-121 398.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1J594@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG1194 A G-specific DNA glycosylase mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 DYD3_k127_4001754_4 349124.Hhal_0376 6.931e-19 94.0 COG2867@1|root,COG2867@2|Bacteria,1QZ93@1224|Proteobacteria,1T41V@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - - DYD3_k127_4001754_2 187272.Mlg_2694 3.045e-95 338.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1WXRZ@135613|Chromatiales 135613|Chromatiales M PFAM AsmA family protein - - - ko:K07289 - - - - ko00000 - - - AsmA DYD3_k127_4001754_3 883080.HMPREF9697_03372 3.427e-56 198.0 COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria,3JYUE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1428) - - - - - - - - - - - - DUF1428 DYD3_k127_4001754_0 240016.ABIZ01000001_gene2374 1.355e-121 417.0 COG2091@1|root,COG2091@2|Bacteria,46VE0@74201|Verrucomicrobia 74201|Verrucomicrobia H Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 DYD3_k127_4001754_5 204669.Acid345_1037 4.529e-10 70.0 COG3595@1|root,COG3595@2|Bacteria,3Y97I@57723|Acidobacteria,2JNRB@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - DYD3_k127_4001754_6 1216007.AOPM01000071_gene1572 2.407e-06 57.0 2CKCT@1|root,32SC5@2|Bacteria,1N1BJ@1224|Proteobacteria,1S8RE@1236|Gammaproteobacteria,2Q2TX@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4001819_2 1288826.MSNKSG1_17571 6.623e-26 115.0 COG5662@1|root,COG5662@2|Bacteria,1NGBV@1224|Proteobacteria,1SGXN@1236|Gammaproteobacteria,46BR4@72275|Alteromonadaceae 1236|Gammaproteobacteria K Putative zinc-finger - - - - - - - - - - - - zf-HC2 DYD3_k127_4001819_1 443152.MDG893_14023 1.23e-30 129.0 COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,46CF3@72275|Alteromonadaceae 1236|Gammaproteobacteria K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_4001819_0 1198232.CYCME_0641 2.636e-111 367.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,460H9@72273|Thiotrichales 72273|Thiotrichales O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group cyoE - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA DYD3_k127_4001819_3 443152.MDG893_17922 2.997e-24 109.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,4697A@72275|Alteromonadaceae 1236|Gammaproteobacteria S signal sequence binding - - - - - - - - - - - - - DYD3_k127_4001819_4 1198232.CYCME_0638 3.214e-15 79.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,462X5@72273|Thiotrichales 72273|Thiotrichales S SURF1 family - - - - - - - - - - - - SURF1 DYD3_k127_402197_2 1304883.KI912532_gene2533 3.629e-62 223.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,2KUNR@206389|Rhodocyclales 206389|Rhodocyclales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP DYD3_k127_402197_0 1260251.SPISAL_05930 1.41e-82 295.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria,1WZ7G@135613|Chromatiales 135613|Chromatiales L Nucleotidyltransferase DNA polymerase involved in DNA repair - - - ko:K14161 - - - - ko00000,ko03400 - - - IMS DYD3_k127_402197_3 292415.Tbd_0830 4.937e-51 188.0 COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,2VUGI@28216|Betaproteobacteria 28216|Betaproteobacteria S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - ko:K13053,ko:K14160 - - - - ko00000,ko03036,ko03400 - - - SulA DYD3_k127_402197_1 382245.ASA_4206 8.339e-82 277.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1Y45U@135624|Aeromonadales 135624|Aeromonadales K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 DYD3_k127_402197_4 311403.Arad_9517 2.371e-21 99.0 COG0633@1|root,COG2114@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,1N5XC@1224|Proteobacteria,2TRGX@28211|Alphaproteobacteria,4BAA0@82115|Rhizobiaceae 28211|Alphaproteobacteria CT Adenylyl- / guanylyl cyclase, catalytic domain cyaA - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Fer2,Guanylate_cyc DYD3_k127_4031730_2 414684.RC1_3864 3.634e-105 349.0 COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2TT52@28211|Alphaproteobacteria,2JQBR@204441|Rhodospirillales 204441|Rhodospirillales P Bacterial extracellular solute-binding protein sbp - - ko:K02048 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - SBP_bac_11 DYD3_k127_4031730_0 1128421.JAGA01000001_gene2449 2.093e-117 399.0 COG3842@1|root,COG3842@2|Bacteria 2|Bacteria P ATPase activity cysA - 3.6.3.25 ko:K02045 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.1,3.A.1.6.3 - - ABC_tran,TOBE_2,TOBE_3 DYD3_k127_4031730_3 743721.Psesu_2270 4.272e-85 297.0 COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales 135614|Xanthomonadales P Phosphate-selective porin O and P - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P DYD3_k127_4031730_4 1185876.BN8_02780 1.085e-45 170.0 COG3350@1|root,COG3350@2|Bacteria,4NR42@976|Bacteroidetes,47XU3@768503|Cytophagia 976|Bacteroidetes S monooxygenase activity - - - - - - - - - - - - YHS DYD3_k127_4031730_9 314285.KT71_13045 0.0006794 49.0 2F0AW@1|root,33TE4@2|Bacteria,1NTNC@1224|Proteobacteria,1SM9M@1236|Gammaproteobacteria,1J90F@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4031730_7 555793.WSK_4187 5.022e-15 87.0 28MSC@1|root,2ZB0S@2|Bacteria,1NG2A@1224|Proteobacteria,2VG0A@28211|Alphaproteobacteria,2KBBC@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD3_k127_4031730_8 322710.Avin_26800 5.33e-10 66.0 2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,1SGTK@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4031730_5 1082931.KKY_123 1.124e-29 124.0 2CBAE@1|root,3343U@2|Bacteria,1Q6VU@1224|Proteobacteria,2UJ1K@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4031730_6 1123392.AQWL01000010_gene2295 4.764e-15 81.0 2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,2VY3B@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4031730_1 1122613.ATUP01000001_gene315 8.55e-108 361.0 COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria,43ZAU@69657|Hyphomonadaceae 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - HlyD_3 DYD3_k127_403663_4 566466.NOR53_903 2.219e-19 91.0 2EMUX@1|root,33FH7@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_403663_1 288000.BBta_3564 9.965e-64 222.0 COG3791@1|root,COG3791@2|Bacteria,1RCYS@1224|Proteobacteria,2U5UG@28211|Alphaproteobacteria,3JUX3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD3_k127_403663_3 1385935.N836_03240 2.137e-22 103.0 2EM9G@1|root,33EYK@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_403663_0 1500890.JQNL01000001_gene1632 6.006e-226 726.0 COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1X4M7@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase DYD3_k127_403663_2 1122612.AUBA01000025_gene3131 1.151e-38 151.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2TUB5@28211|Alphaproteobacteria,2K0HK@204457|Sphingomonadales 204457|Sphingomonadales S Belongs to the UPF0176 family - - - ko:K07146 - - - - ko00000 - - - Rhodanese DYD3_k127_4042298_2 228405.HNE_3087 8.79e-81 280.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,43WVB@69657|Hyphomonadaceae 28211|Alphaproteobacteria P K -dependent Na Ca - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex DYD3_k127_4042298_0 999541.bgla_1g32730 5.105e-103 343.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHUJ@28216|Betaproteobacteria,1K1GV@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C DYD3_k127_4042298_1 414684.RC1_2752 1.782e-88 302.0 COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U7R8@28211|Alphaproteobacteria,2JUQC@204441|Rhodospirillales 204441|Rhodospirillales S Methyltransferase - - - - - - - - - - - - - DYD3_k127_4049187_3 1163407.UU7_02417 4.652e-10 61.0 COG4496@1|root,COG4496@2|Bacteria,1NAAX@1224|Proteobacteria,1SG3S@1236|Gammaproteobacteria,1X7DY@135614|Xanthomonadales 135614|Xanthomonadales S protein, YerC YecD - - - - - - - - - - - - Trp_repressor DYD3_k127_4049187_1 1123073.KB899242_gene1406 5.517e-96 322.0 COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1X4SF@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C DYD3_k127_4049187_0 1500893.JQNB01000001_gene2016 1.433e-137 459.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1X4GX@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh DYD3_k127_4049187_2 1500890.JQNL01000001_gene3225 1.501e-58 215.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1X3SR@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD3_k127_4058093_2 1158146.KB907126_gene1609 8.459e-78 263.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1WW35@135613|Chromatiales 135613|Chromatiales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD DYD3_k127_4058093_3 713587.THITH_04360 4.851e-67 237.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,1WWBK@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr DYD3_k127_4058093_4 187272.Mlg_0812 4.71e-52 199.0 COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WVYN@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03612 - - - - ko00000 - - - FMN_bind DYD3_k127_4058093_1 396588.Tgr7_2629 6.818e-114 381.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE DYD3_k127_4058093_0 2340.JV46_10800 2.437e-139 459.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfC - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB DYD3_k127_4058093_5 748247.AZKH_1802 2.302e-50 183.0 COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,2KVNK@206389|Rhodocyclales 206389|Rhodocyclales C Part of a membrane complex involved in electron transport - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4_21 DYD3_k127_407435_1 1134474.O59_001871 2.008e-199 643.0 COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,1S0F2@1236|Gammaproteobacteria,1FFXH@10|Cellvibrio 1236|Gammaproteobacteria E Peptidase family M3 - - 3.4.24.15 ko:K01392 ko04614,ko05143,map04614,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M3 DYD3_k127_407435_0 745310.G432_02550 3.4e-258 812.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria,2K0PD@204457|Sphingomonadales 204457|Sphingomonadales EU Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 DYD3_k127_4087951_2 1149133.ppKF707_0207 2.994e-24 105.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1YF28@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase DYD3_k127_4087951_1 754476.Q7A_1352 3.842e-136 438.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,45ZX8@72273|Thiotrichales 72273|Thiotrichales C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA DYD3_k127_4087951_0 1049564.TevJSym_aq00800 6.293e-166 529.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1J53T@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA DYD3_k127_4111740_1 936455.KI421499_gene2165 6.911e-49 181.0 COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,3JU44@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - - DYD3_k127_4111740_0 1565129.JSFF01000004_gene3222 3.39e-92 315.0 COG0729@1|root,COG0729@2|Bacteria,1PFDU@1224|Proteobacteria,1RMUN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag DYD3_k127_4111740_2 1265313.HRUBRA_02382 1.553e-38 148.0 COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,1S4NR@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1226 Kef-type K transport systems - - - - - - - - - - - - Ion_trans_2 DYD3_k127_4111740_3 1396141.BATP01000027_gene1109 2.47e-33 132.0 COG4775@1|root,COG4775@2|Bacteria,46UZC@74201|Verrucomicrobia,2IV9A@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Surface antigen - - - - - - - - - - - - Bac_surface_Ag DYD3_k127_4128603_2 1273538.G159_17110 9.206e-53 205.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,4HCCP@91061|Bacilli,26FJQ@186818|Planococcaceae 91061|Bacilli S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 DYD3_k127_4128603_0 1123270.ATUR01000002_gene2397 4.962e-154 512.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,2K18M@204457|Sphingomonadales 204457|Sphingomonadales C Dehydrogenase - - 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 - R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh DYD3_k127_4128603_1 1137281.D778_02007 1.001e-97 329.0 COG3278@1|root,COG3278@2|Bacteria,4NIGA@976|Bacteroidetes,1HZJ7@117743|Flavobacteriia 976|Bacteroidetes O Cytochrome C and Quinol oxidase polypeptide I - - 1.7.2.5 ko:K04561 ko00910,ko01120,map00910,map01120 M00529 R00294 RC02794 ko00000,ko00001,ko00002,ko01000 3.D.4.10 - - COX1 DYD3_k127_4132674_2 754477.Q7C_1713 2.477e-28 115.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,460E7@72273|Thiotrichales 72273|Thiotrichales E Pyridoxal-phosphate dependent enzyme - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP DYD3_k127_4132674_0 322710.Avin_23140 4.217e-105 351.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator cysB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD3_k127_4132674_3 351348.Maqu_1880 0.0005241 49.0 COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae 1236|Gammaproteobacteria S SH3 domain protein ygiM - - ko:K07184 - - - - ko00000 - - - SH3_3 DYD3_k127_4132674_1 713586.KB900536_gene521 5.84e-68 239.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1WWVE@135613|Chromatiales 135613|Chromatiales M PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C - - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 DYD3_k127_413847_3 1040982.AXAL01000029_gene4286 3.934e-07 51.0 COG1765@1|root,COG1765@2|Bacteria,1RBJN@1224|Proteobacteria,2VF54@28211|Alphaproteobacteria,43MJG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD3_k127_413847_0 1121939.L861_01740 7.875e-168 539.0 COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,1RNQP@1236|Gammaproteobacteria 1236|Gammaproteobacteria P oxidoreductase - - - ko:K07222 - - - - ko00000 - - - Pyr_redox_3 DYD3_k127_413847_1 1123269.NX02_27645 1.594e-155 507.0 COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria,2TW44@28211|Alphaproteobacteria,2K7FJ@204457|Sphingomonadales 204457|Sphingomonadales IT Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 DYD3_k127_413847_2 566466.NOR53_1562 2.597e-44 165.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1S1X6@1236|Gammaproteobacteria,1J89Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD3_k127_4154209_0 518766.Rmar_2366 1.44e-97 333.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1FIKX@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD3_k127_4154209_2 1123279.ATUS01000001_gene2416 3.195e-66 241.0 COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria,1J93K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Opacity family porin protein - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 DYD3_k127_4154209_1 314285.KT71_01630 8.895e-93 312.0 COG4313@1|root,COG4313@2|Bacteria,1MWCX@1224|Proteobacteria,1S4A1@1236|Gammaproteobacteria,1J9GX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg DYD3_k127_4170062_0 290397.Adeh_2603 6.622e-83 304.0 COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,42VEM@68525|delta/epsilon subdivisions,2WRGV@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - - DYD3_k127_4170062_2 1535422.ND16A_0737 4.365e-55 201.0 COG2863@1|root,COG2863@2|Bacteria,1R8K9@1224|Proteobacteria,1S1Q4@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM Cytochrome C - - - ko:K17230 ko00920,ko01120,map00920,map01120 - R09499 - ko00000,ko00001 - - - Cytochrome_CBB3 DYD3_k127_4170062_1 156889.Mmc1_1587 1.944e-64 227.0 COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,2TURW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome c-type protein - - - ko:K02569 - - - - ko00000 - - - Cytochrom_NNT DYD3_k127_4170062_3 1410619.SRDD_34710 9.853e-22 101.0 COG3631@1|root,COG3631@2|Bacteria,1NIDX@1224|Proteobacteria,1SZRA@1236|Gammaproteobacteria 1236|Gammaproteobacteria G SnoaL-like domain - - - - - - - - - - - - SnoaL_2 DYD3_k127_4170062_4 1286106.MPL1_01637 5.705e-13 70.0 COG0517@1|root,COG0517@2|Bacteria,1QTZR@1224|Proteobacteria,1S7SY@1236|Gammaproteobacteria,4614G@72273|Thiotrichales 72273|Thiotrichales S CBS domain - - - - - - - - - - - - CBS DYD3_k127_4178741_3 1121374.KB891575_gene801 1.333e-35 136.0 2CEWZ@1|root,33QME@2|Bacteria,1NTHN@1224|Proteobacteria,1SKH8@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4178741_2 697282.Mettu_3582 2.912e-52 189.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,1S40Q@1236|Gammaproteobacteria,1XGHK@135618|Methylococcales 135618|Methylococcales J Transcription elongation factor, GreA/GreB, C-term - - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB DYD3_k127_4178741_1 314285.KT71_07359 2.714e-52 199.0 COG2930@1|root,COG2930@2|Bacteria,1RCYH@1224|Proteobacteria,1SMPZ@1236|Gammaproteobacteria,1J82I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 DYD3_k127_4178741_0 264462.Bd2628 9.27e-138 447.0 COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria,1QY2E@1224|Proteobacteria,43C9S@68525|delta/epsilon subdivisions,2WTXI@28221|Deltaproteobacteria 28221|Deltaproteobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - FMN_red,Rieske DYD3_k127_4201728_0 1128912.GMES_1315 6.017e-105 350.0 COG0665@1|root,COG0665@2|Bacteria,1Q9VR@1224|Proteobacteria,1S0R4@1236|Gammaproteobacteria,46A05@72275|Alteromonadaceae 1236|Gammaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO DYD3_k127_4201728_1 999611.KI421504_gene673 1.514e-10 63.0 COG4312@1|root,COG4312@2|Bacteria,1QIBA@1224|Proteobacteria,2TTFP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 DYD3_k127_4226556_1 1123277.KB893181_gene2302 7.708e-139 451.0 COG0738@1|root,COG0738@2|Bacteria,4NHI6@976|Bacteroidetes,47KNG@768503|Cytophagia 976|Bacteroidetes G PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_4226556_0 1129374.AJE_10749 2.123e-174 561.0 COG1629@1|root,COG4771@2|Bacteria,1QUWS@1224|Proteobacteria,1T23Y@1236|Gammaproteobacteria,465FJ@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_4230518_1 396588.Tgr7_2890 2.644e-155 501.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1WXEF@135613|Chromatiales 135613|Chromatiales G Belongs to the pyruvate kinase family - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C DYD3_k127_4230518_0 1234364.AMSF01000027_gene3450 2.096e-173 568.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,1X56U@135614|Xanthomonadales 135614|Xanthomonadales S Penicillin acylase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase DYD3_k127_4231599_2 251221.35214709 1.068e-78 265.0 COG1132@1|root,COG1132@2|Bacteria,1G0EY@1117|Cyanobacteria 1117|Cyanobacteria V ABC-type multidrug transport system ATPase and permease - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD3_k127_4231599_3 1123253.AUBD01000001_gene1828 4.762e-74 265.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1X587@135614|Xanthomonadales 135614|Xanthomonadales S Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA DYD3_k127_4231599_9 1185876.BN8_02076 1.08e-13 83.0 COG3743@1|root,COG3743@2|Bacteria,4NSZH@976|Bacteroidetes,47PEM@768503|Cytophagia 976|Bacteroidetes S rRNA binding - - - - - - - - - - - - HHH_5 DYD3_k127_4231599_0 382464.ABSI01000012_gene2200 9.198e-96 340.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C DYD3_k127_4231599_6 110319.CF8_3395 1.285e-26 117.0 COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4DR3R@85009|Propionibacteriales 201174|Actinobacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_1 DYD3_k127_4231599_1 641491.DND132_0252 6.185e-85 300.0 COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2M7ZK@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Peptidase M23 - - - - - - - - - - - - Peptidase_M23 DYD3_k127_4231599_7 338963.Pcar_2706 4.125e-19 98.0 COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,42N61@68525|delta/epsilon subdivisions,2WM0D@28221|Deltaproteobacteria,43S57@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 DYD3_k127_4231599_10 1415779.JOMH01000001_gene1611 9.55e-10 61.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S5DB@1236|Gammaproteobacteria,1X4XD@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF502) YH67_14670 - - - - - - - - - - - DUF502 DYD3_k127_4231599_4 283942.IL1524 1.389e-53 203.0 2E1MA@1|root,32WYJ@2|Bacteria,1N6KY@1224|Proteobacteria,1SBEM@1236|Gammaproteobacteria,2QFNB@267893|Idiomarinaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4231599_8 1415779.JOMH01000001_gene512 7.402e-16 81.0 2EK6E@1|root,33DWT@2|Bacteria,1NJFR@1224|Proteobacteria,1SHVU@1236|Gammaproteobacteria,1XBBY@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF3185) - - - - - - - - - - - - DUF3185 DYD3_k127_4231599_5 452637.Oter_3042 5.972e-50 182.0 COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia,3K9NS@414999|Opitutae 414999|Opitutae M Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD3_k127_4232673_0 913325.N799_10705 0.0 1366.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1X46R@135614|Xanthomonadales 135614|Xanthomonadales E glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N DYD3_k127_4232673_1 760117.JN27_21585 1.406e-97 328.0 COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,473A2@75682|Oxalobacteraceae 28216|Betaproteobacteria G Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily gpmA - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 DYD3_k127_4232673_2 1123261.AXDW01000014_gene3363 1.683e-65 229.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1S3WC@1236|Gammaproteobacteria,1X6GD@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep DYD3_k127_4232718_4 1121374.KB891586_gene2767 1.642e-08 58.0 COG2010@1|root,COG2010@2|Bacteria,1N5P8@1224|Proteobacteria,1S9K3@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C DYD3_k127_4232718_1 666685.R2APBS1_0575 4.274e-181 573.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X4AH@135614|Xanthomonadales 135614|Xanthomonadales E cystathionine - - 4.4.1.1 ko:K01758 ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230 M00338 R00782,R01001,R02408,R04770,R04930,R09366 RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP DYD3_k127_4232718_0 666685.R2APBS1_0565 1.72e-188 599.0 COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X4GC@135614|Xanthomonadales 135614|Xanthomonadales E Cystathionine beta-synthase cysB - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP DYD3_k127_4232718_2 1122604.JONR01000009_gene2404 4.832e-74 261.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales 135614|Xanthomonadales J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 DYD3_k127_4232718_3 1109445.AGSX01000111_gene46 2.344e-57 207.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria,1Z1TZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase DYD3_k127_4247541_0 1121875.KB907553_gene18 4.812e-127 426.0 COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,1HZYC@117743|Flavobacteriia 976|Bacteroidetes M soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein mltF - - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT DYD3_k127_4247541_1 913865.DOT_0140 6.492e-89 304.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,2606H@186807|Peptococcaceae 186801|Clostridia E Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 DYD3_k127_4251760_1 187272.Mlg_2567 2.381e-59 216.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1X0WV@135613|Chromatiales 135613|Chromatiales S Divergent polysaccharide deacetylase - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 DYD3_k127_4251760_0 765910.MARPU_16560 1.678e-108 362.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1WVW7@135613|Chromatiales 135613|Chromatiales M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 DYD3_k127_4275783_0 1211114.ALIP01000115_gene1475 5.377e-230 725.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales 135614|Xanthomonadales IQ Activates fatty acids by binding to coenzyme A rpfB - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD3_k127_4275783_3 1122194.AUHU01000005_gene1007 1.226e-63 229.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,466ZZ@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG2755 Lysophospholipase L1 and related esterases tesA GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365 Lipase_GDSL_2 DYD3_k127_4275783_1 472759.Nhal_2579 5.613e-86 291.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1WW8Q@135613|Chromatiales 135613|Chromatiales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_4275783_2 1442599.JAAN01000010_gene212 3.334e-70 250.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1X341@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX DYD3_k127_4287553_0 519989.ECTPHS_06532 9.605e-116 380.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1WWRX@135613|Chromatiales 135613|Chromatiales O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 DYD3_k127_4287553_1 1177181.T9A_00502 1.94e-43 163.0 COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales 135619|Oceanospirillales H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB DYD3_k127_4287553_2 187272.Mlg_2523 3.174e-41 158.0 COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1WYX8@135613|Chromatiales 135613|Chromatiales H PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK DYD3_k127_4287553_3 435908.IDSA_11790 1.595e-08 62.0 COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,1RR5H@1236|Gammaproteobacteria,2QFX8@267893|Idiomarinaceae 1236|Gammaproteobacteria M Peptidase family S41 - - - - - - - - - - - - PDZ,PDZ_2,Peptidase_S41 DYD3_k127_429700_3 1397527.Q670_04240 8.097e-24 103.0 COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,1XHZG@135619|Oceanospirillales 135619|Oceanospirillales E Belongs to the glutaminase family glsA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase DYD3_k127_429700_0 1506583.JQJY01000001_gene553 7.308e-140 456.0 COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,1I5BI@117743|Flavobacteriia,2NVIG@237|Flavobacterium 976|Bacteroidetes S COG NOG10142 non supervised orthologous group - - - - - - - - - - - - - DYD3_k127_429700_1 1121373.KB903665_gene3093 2.261e-134 437.0 COG2159@1|root,COG2159@2|Bacteria,4P1VU@976|Bacteroidetes 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 DYD3_k127_429700_2 234267.Acid_5407 1.446e-91 308.0 COG3170@1|root,COG3170@2|Bacteria,3Y9A5@57723|Acidobacteria 2|Bacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - Amidase_6 DYD3_k127_4310481_5 349124.Hhal_0941 5.98e-41 156.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1WWU0@135613|Chromatiales 135613|Chromatiales F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD3_k127_4310481_6 519989.ECTPHS_03909 4.037e-33 137.0 COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yqgF GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX DYD3_k127_4310481_2 765910.MARPU_15875 2.423e-61 217.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1WX8T@135613|Chromatiales 135613|Chromatiales K Belongs to the UPF0301 (AlgH) family - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 DYD3_k127_4310481_8 1122134.KB893650_gene182 2.472e-31 135.0 COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria,1XJV0@135619|Oceanospirillales 135619|Oceanospirillales M Periplasmic protein TonB, links inner and outer membranes tonB - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD3_k127_4310481_0 519989.ECTPHS_03879 4.324e-127 415.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1WVY1@135613|Chromatiales 135613|Chromatiales HJ Belongs to the prokaryotic GSH synthase family gshB - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N DYD3_k127_4310481_3 1121015.N789_09075 1.535e-59 209.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1X6HP@135614|Xanthomonadales 135614|Xanthomonadales KT response regulator pilG - - ko:K02657 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg DYD3_k127_4310481_4 519989.ECTPHS_03869 2.973e-44 163.0 COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1WYZY@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg DYD3_k127_4310481_7 1123020.AUIE01000025_gene4780 2.093e-32 132.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1YCQV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT Two component signalling adaptor domain pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW DYD3_k127_4310481_1 106370.Francci3_3738 1.214e-65 233.0 COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4ERJD@85013|Frankiales 201174|Actinobacteria C PFAM Luciferase-like - - - - - - - - - - - - Bac_luciferase DYD3_k127_4320172_2 375286.mma_2596 1.336e-16 79.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae 28216|Betaproteobacteria H Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA DYD3_k127_4320172_0 477641.MODMU_3424 3.028e-89 300.0 COG1028@1|root,COG1028@2|Bacteria,2GKE1@201174|Actinobacteria 201174|Actinobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 DYD3_k127_4320172_1 861299.J421_0685 3.898e-40 154.0 COG1670@1|root,COG1670@2|Bacteria,1ZUZX@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 DYD3_k127_4320548_2 472759.Nhal_0144 3.193e-69 241.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RSN1@1236|Gammaproteobacteria,1WVUQ@135613|Chromatiales 135613|Chromatiales I PFAM Fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase DYD3_k127_4320548_4 393595.ABO_0216 8.997e-20 94.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1XMCR@135619|Oceanospirillales 135619|Oceanospirillales J there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 DYD3_k127_4320548_3 743974.MBO_01060 3.678e-34 136.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,3NNZ1@468|Moraxellaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 DYD3_k127_4320548_1 396588.Tgr7_0100 3.225e-74 256.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1WXFP@135613|Chromatiales 135613|Chromatiales L Belongs to the UPF0758 family - - - ko:K03630 - - - - ko00000 - - - RadC DYD3_k127_4320548_0 314278.NB231_11229 1.944e-132 440.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales 135613|Chromatiales H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine - - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein DYD3_k127_4321158_0 1117318.PRUB_11196 7.221e-72 260.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - OMP_b-brl_3,Plug,TonB_dep_Rec DYD3_k127_4322214_0 998674.ATTE01000001_gene2279 1.924e-263 824.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,46012@72273|Thiotrichales 72273|Thiotrichales F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS DYD3_k127_4322214_1 314285.KT71_01620 9.612e-233 733.0 COG4805@1|root,COG4805@2|Bacteria,1R4HM@1224|Proteobacteria,1SKZF@1236|Gammaproteobacteria,1J9TG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - - DYD3_k127_4322214_2 1122137.AQXF01000005_gene1213 9.415e-219 712.0 COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,2TW6Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_4322214_3 1163409.UUA_13807 2.032e-51 186.0 COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1X4K3@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - - - - - - - - - - HemN_C,Radical_SAM DYD3_k127_4325170_0 1452718.JBOY01000139_gene1472 1.91e-299 931.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,1T1W9@1236|Gammaproteobacteria 1236|Gammaproteobacteria V COG5265 ABC-type transport system involved in Fe-S cluster assembly permease and ATPase components atmA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD3_k127_4325170_1 314285.KT71_01630 1.748e-16 80.0 COG4313@1|root,COG4313@2|Bacteria,1MWCX@1224|Proteobacteria,1S4A1@1236|Gammaproteobacteria,1J9GX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg DYD3_k127_4337992_9 522772.Dacet_0599 1.013e-18 94.0 COG2982@1|root,COG2982@2|Bacteria 2|Bacteria M Protein involved in outer membrane biogenesis - - - - - - - - - - - - Big_2,DUF4347,DctA-YdbH,Flg_new,He_PIG,SdrD_B DYD3_k127_4337992_8 756272.Plabr_2236 1.105e-40 164.0 COG0392@1|root,COG0392@2|Bacteria,2J055@203682|Planctomycetes 203682|Planctomycetes S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM DYD3_k127_4337992_7 1142394.PSMK_01080 2.535e-47 183.0 28HYD@1|root,2Z83U@2|Bacteria 2|Bacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 DYD3_k127_4337992_3 1173029.JH980292_gene2498 1.292e-119 396.0 COG0726@1|root,COG0726@2|Bacteria,1G3JU@1117|Cyanobacteria,1HABD@1150|Oscillatoriales 1117|Cyanobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD3_k127_4337992_4 1379698.RBG1_1C00001G1537 2.945e-111 373.0 COG0673@1|root,COG0673@2|Bacteria,2NP38@2323|unclassified Bacteria 2|Bacteria S Oxidoreductase family, NAD-binding Rossmann fold - - 2.3.1.201 ko:K13018 ko00520,map00520 - R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 - - - GFO_IDH_MocA,GFO_IDH_MocA_C,Hexapep,Hexapep_2 DYD3_k127_4337992_5 1307759.JOMJ01000003_gene2003 1.096e-99 339.0 COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,42MSY@68525|delta/epsilon subdivisions,2WJXR@28221|Deltaproteobacteria,2M98J@213115|Desulfovibrionales 28221|Deltaproteobacteria M Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.23 ko:K13019 ko00520,map00520 - R09600 RC00290 ko00000,ko00001,ko01000,ko01005 - - - Epimerase_2 DYD3_k127_4337992_2 880073.Calab_2801 1.179e-133 443.0 COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria 2|Bacteria E Belongs to the DegT DnrJ EryC1 family degT - - - - - - - - - - - DegT_DnrJ_EryC1 DYD3_k127_4337992_6 335541.Swol_0704 6.52e-80 272.0 COG0110@1|root,COG0110@2|Bacteria,1TT21@1239|Firmicutes,24CCH@186801|Clostridia,42KPW@68298|Syntrophomonadaceae 186801|Clostridia S Hexapeptide repeat of succinyl-transferase wbpD - 2.3.1.201 ko:K13018 ko00520,map00520 - R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 - - - Hexapep,Hexapep_2 DYD3_k127_4337992_0 63737.Npun_F5429 1.389e-157 509.0 COG1232@1|root,COG1232@2|Bacteria,1G465@1117|Cyanobacteria 1117|Cyanobacteria H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase DYD3_k127_4337992_1 1469607.KK073768_gene2394 1.116e-141 456.0 COG0451@1|root,COG0451@2|Bacteria,1G0QH@1117|Cyanobacteria,1HJ5Z@1161|Nostocales 1117|Cyanobacteria M PFAM NAD dependent epimerase dehydratase family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd DYD3_k127_4337992_10 143224.JQMD01000002_gene3421 1.368e-08 58.0 COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,1HYRX@117743|Flavobacteriia 976|Bacteroidetes M Pfam Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 DYD3_k127_4343136_3 1237149.C900_02493 7.45e-14 76.0 COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2 DYD3_k127_4343136_0 439235.Dalk_0909 1.759e-141 460.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,42PNZ@68525|delta/epsilon subdivisions,2WM13@28221|Deltaproteobacteria,2MJSE@213118|Desulfobacterales 28221|Deltaproteobacteria C CoA-transferase family III - - 5.1.99.4 ko:K01796 ko00120,ko01100,ko04146,map00120,map01100,map04146 M00104 R08734,R08739 RC02345 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 DYD3_k127_4343136_1 1487953.JMKF01000028_gene1341 3.065e-107 359.0 COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1H99G@1150|Oscillatoriales 1117|Cyanobacteria P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA DYD3_k127_4343136_2 1123399.AQVE01000032_gene788 6.653e-35 137.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,461NF@72273|Thiotrichales 72273|Thiotrichales E Aminotransferase class-III - - - - - - - - - - - - Aminotran_3 DYD3_k127_4348727_3 1128421.JAGA01000002_gene949 4.871e-28 116.0 COG2261@1|root,COG2261@2|Bacteria 2|Bacteria S Transglycosylase associated protein mltA - - - - - - - - - - - Transgly_assoc DYD3_k127_4348727_0 1123392.AQWL01000006_gene640 6.63e-74 261.0 COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,2VQ1F@28216|Betaproteobacteria 28216|Betaproteobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2,TPR_16,TPR_17 DYD3_k127_4348727_4 1385515.N791_03520 8.698e-24 107.0 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria,1X82S@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_4348727_2 443143.GM18_2096 1.723e-39 155.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales 28221|Deltaproteobacteria T GGDEF domain containing protein - - - - - - - - - - - - EAL,GGDEF,PAS_9 DYD3_k127_4348727_1 1122194.AUHU01000005_gene815 1.696e-73 262.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,464IS@72275|Alteromonadaceae 1236|Gammaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport DYD3_k127_4395593_1 1479237.JMLY01000001_gene1395 7.11e-41 156.0 COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,1S4EZ@1236|Gammaproteobacteria,46B1C@72275|Alteromonadaceae 1236|Gammaproteobacteria Q protein, possibly involved in aromatic compounds catabolism paaI GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_1225,iEC55989_1330.EC55989_1532,iECDH10B_1368.ECDH10B_1521,iECDH1ME8569_1439.EcDH1_2249,iECIAI1_1343.ECIAI1_1396,iECO103_1326.ECO103_1533,iECO111_1330.ECO111_1790,iECO26_1355.ECO26_2000,iECSE_1348.ECSE_1481,iEKO11_1354.EKO11_2417,iETEC_1333.ETEC_1471,iEcDH1_1363.EcDH1_2249,iEcE24377_1341.EcE24377A_1581,iEcHS_1320.EcHS_A1483,iEcolC_1368.EcolC_2259,iUMNK88_1353.UMNK88_1803,iY75_1357.Y75_RS07340 4HBT DYD3_k127_4395593_0 314278.NB231_10568 3.187e-91 310.0 COG3327@1|root,COG3327@2|Bacteria,1R4IF@1224|Proteobacteria,1RR7B@1236|Gammaproteobacteria 1236|Gammaproteobacteria K phenylacetic acid degradation operon negative regulatory protein paaX GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K02616 - - - - ko00000,ko03000 - - - PaaX,PaaX_C DYD3_k127_4395593_2 518766.Rmar_1556 7.407e-15 76.0 COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes 976|Bacteroidetes CI phenylacetic acid degradation protein paaN paaN - 1.2.1.91,3.3.2.12 ko:K02618 ko00360,ko01120,map00360,map01120 - R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 - - - Aldedh,DUF1569,MaoC_dehydratas DYD3_k127_4406481_0 491916.RHECIAT_CH0000120 5.38e-216 677.0 COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,2U4SQ@28211|Alphaproteobacteria,4BC89@82115|Rhizobiaceae 28211|Alphaproteobacteria E Amino acid permease potE - - ko:K03756,ko:K03759 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 DYD3_k127_4406481_1 1380391.JIAS01000012_gene4191 1e-199 627.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2TSSN@28211|Alphaproteobacteria,2JUZY@204441|Rhodospirillales 204441|Rhodospirillales E Orn/Lys/Arg decarboxylase, N-terminal domain - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N DYD3_k127_4417667_4 1163409.UUA_16013 5.596e-38 151.0 COG3407@1|root,COG3407@2|Bacteria,1N5EZ@1224|Proteobacteria,1S19T@1236|Gammaproteobacteria,1X9HF@135614|Xanthomonadales 135614|Xanthomonadales I GHMP kinases N terminal domain - - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_N DYD3_k127_4417667_2 572477.Alvin_0767 4.241e-87 298.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales 135613|Chromatiales H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K00795,ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt DYD3_k127_4417667_3 1265313.HRUBRA_00271 2.676e-86 301.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH DYD3_k127_4417667_1 671143.DAMO_0658 3.016e-120 411.0 COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein exeA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 DYD3_k127_4417667_5 1123261.AXDW01000007_gene2175 7.885e-10 68.0 COG5373@1|root,COG5373@2|Bacteria,1QZY0@1224|Proteobacteria,1SDQG@1236|Gammaproteobacteria,1X8J6@135614|Xanthomonadales 135614|Xanthomonadales S Type II secretion system protein B - - - - - - - - - - - - T2SSB DYD3_k127_4417667_0 1384054.N790_10990 1.132e-130 439.0 COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,1SHAC@1236|Gammaproteobacteria,1X3IB@135614|Xanthomonadales 135614|Xanthomonadales S Dak2 - - - ko:K07030 - - - - ko00000 - - - Dak2,DegV DYD3_k127_4433103_2 1278309.KB907099_gene2933 2.984e-163 523.0 COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4,Fer4_5,Pyr_redox_3 DYD3_k127_4433103_7 1095769.CAHF01000011_gene2246 1.5e-110 366.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,472BN@75682|Oxalobacteraceae 28216|Betaproteobacteria M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD3_k127_4433103_12 1500890.JQNL01000001_gene682 5.57e-17 89.0 COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1X84H@135614|Xanthomonadales 135614|Xanthomonadales L competence protein ComEA comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3 DYD3_k127_4433103_9 1056512.D515_01939 1.628e-73 263.0 COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,1XU1S@135623|Vibrionales 135623|Vibrionales G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane lapB - - ko:K19804 - - - - ko00000 - - - TPR_16,TPR_19,TPR_7,TPR_8 DYD3_k127_4433103_13 396588.Tgr7_1545 0.0001065 50.0 COG5416@1|root,COG5416@2|Bacteria,1NGPH@1224|Proteobacteria,1SGDB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Lipopolysaccharide assembly protein A domain - - - ko:K08992 - - - - ko00000 - - - LapA_dom DYD3_k127_4433103_11 545276.KB898726_gene1030 7.066e-43 158.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales 135613|Chromatiales K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD - - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD3_k127_4433103_1 765914.ThisiDRAFT_2029 4.42e-266 830.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1WVVK@135613|Chromatiales 135613|Chromatiales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 DYD3_k127_4433103_10 187272.Mlg_0930 1.823e-71 250.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1WXNU@135613|Chromatiales 135613|Chromatiales F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin DYD3_k127_4433103_5 870187.Thini_0762 8.814e-144 471.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,46046@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase DYD3_k127_4433103_6 84531.JMTZ01000022_gene4194 4.983e-135 439.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1X4R7@135614|Xanthomonadales 135614|Xanthomonadales E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT DYD3_k127_4433103_3 713586.KB900536_gene478 1.069e-158 509.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,1WWZH@135613|Chromatiales 135613|Chromatiales EH D-isomer specific 2-hydroxyacid dehydrogenase - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C DYD3_k127_4433103_4 1397527.Q670_15495 9.354e-151 488.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1XIJ6@135619|Oceanospirillales 135619|Oceanospirillales E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 DYD3_k127_4433103_0 396588.Tgr7_1535 0.0 1240.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1WXK8@135613|Chromatiales 135613|Chromatiales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV DYD3_k127_4433103_8 396588.Tgr7_1531 7.182e-91 310.0 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1WWJ0@135613|Chromatiales 135613|Chromatiales F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine mtaD - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 DYD3_k127_4478491_0 1121904.ARBP01000003_gene6356 3.997e-186 631.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y DYD3_k127_4478491_2 999611.KI421506_gene4026 1.403e-53 194.0 COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TSWP@28211|Alphaproteobacteria 28211|Alphaproteobacteria E lysine exporter protein (LysE YggA) - - - - - - - - - - - - LysE DYD3_k127_4478491_6 1123377.AUIV01000009_gene2664 2.927e-13 70.0 COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - Rhomboid DYD3_k127_4478491_4 420662.Mpe_A1130 2.909e-42 160.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2VQB1@28216|Betaproteobacteria,1KKR5@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Eukaryotic integral membrane protein (DUF1751) - - - - - - - - - - - - Rhomboid DYD3_k127_4478491_1 1123377.AUIV01000020_gene2477 3.471e-118 401.0 COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,1RQUG@1236|Gammaproteobacteria,1X59Q@135614|Xanthomonadales 135614|Xanthomonadales S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 DYD3_k127_4478491_3 1384054.N790_09035 2.02e-47 178.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1X6M0@135614|Xanthomonadales 135614|Xanthomonadales S LemA family - - - - - - - - - - - - LemA DYD3_k127_4478491_5 1565129.JSFF01000008_gene2694 1.352e-41 160.0 COG2258@1|root,COG2258@2|Bacteria,1PBZ2@1224|Proteobacteria,1S8N6@1236|Gammaproteobacteria,2QCAW@267890|Shewanellaceae 1236|Gammaproteobacteria S MOSC domain - - - - - - - - - - - - MOSC DYD3_k127_4480306_1 754477.Q7C_1589 3.77e-12 70.0 2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria,462RV@72273|Thiotrichales 72273|Thiotrichales - - - - - - - - - - - - - - - DYD3_k127_4480306_2 1026882.MAMP_02026 8.327e-09 66.0 COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1T42I@1236|Gammaproteobacteria,460XW@72273|Thiotrichales 72273|Thiotrichales NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 DYD3_k127_4480306_0 314285.KT71_11675 6.273e-223 698.0 COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,1T0HG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4142) - - - - - - - - - - - - DUF305 DYD3_k127_4509020_2 1123257.AUFV01000007_gene311 1.856e-14 73.0 COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1X3QR@135614|Xanthomonadales 135614|Xanthomonadales S Urate oxidase N-terminal - - - - - - - - - - - - Urate_ox_N DYD3_k127_4509020_1 1286093.C266_10711 6.095e-63 237.0 COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,2VKME@28216|Betaproteobacteria,1KFI5@119060|Burkholderiaceae 28216|Betaproteobacteria O Xanthine dehydrogenase accessory protein XdhC xdhC - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI DYD3_k127_4509020_0 62928.azo2212 7.361e-184 583.0 COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,2KV6J@206389|Rhodocyclales 206389|Rhodocyclales F COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B - - 1.17.1.4 ko:K13482 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD3_k127_4514534_0 1442599.JAAN01000030_gene2146 2.103e-185 588.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1X4Q2@135614|Xanthomonadales 135614|Xanthomonadales S transporter oliA - - - - - - - - - - - OPT DYD3_k127_4531397_2 1122603.ATVI01000011_gene2091 2.824e-53 189.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1X43R@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS DYD3_k127_4531397_1 1122603.ATVI01000008_gene2177 1.661e-54 200.0 COG1309@1|root,COG1309@2|Bacteria,1MYYA@1224|Proteobacteria,1SZK2@1236|Gammaproteobacteria,1X6U7@135614|Xanthomonadales 135614|Xanthomonadales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N DYD3_k127_4531397_0 1122604.JONR01000036_gene3795 1.586e-82 284.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1X38S@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K18298,ko:K19586 - M00641,M00767 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2.47,8.A.1 - - Biotin_lipoyl_2,HlyD_D23 DYD3_k127_4539137_2 1335757.SPICUR_01755 3.298e-162 514.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1WVWR@135613|Chromatiales 135613|Chromatiales H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N DYD3_k127_4539137_0 391615.ABSJ01000042_gene2272 3.286e-240 749.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1J8WH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - iYL1228.KPN_02462 AdoHcyase,AdoHcyase_NAD DYD3_k127_4539137_3 765911.Thivi_0500 3.776e-58 211.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1WXST@135613|Chromatiales 135613|Chromatiales S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA - 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos DYD3_k127_4539137_4 329726.AM1_4632 7.714e-51 192.0 COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria 1117|Cyanobacteria S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB DYD3_k127_4539137_5 1469245.JFBG01000021_gene1194 5.896e-23 98.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,1SC8Q@1236|Gammaproteobacteria,1WZ6V@135613|Chromatiales 135613|Chromatiales C PFAM Rubredoxin-type Fe(Cys)4 protein - - - - - - - - - - - - Rubredoxin DYD3_k127_4539137_1 1198232.CYCME_0584 1.245e-184 584.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales 72273|Thiotrichales H PFAM aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD3_k127_455274_0 1121104.AQXH01000001_gene1413 2.885e-269 866.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran DYD3_k127_455274_1 1121104.AQXH01000001_gene1412 5.445e-186 593.0 COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran DYD3_k127_4556264_0 314285.KT71_12345 2.454e-289 908.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T1MR@1236|Gammaproteobacteria,1J7KC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_4556264_5 265072.Mfla_1228 2.67e-14 77.0 2EGMT@1|root,31BJK@2|Bacteria,1Q7EI@1224|Proteobacteria,2VZ0N@28216|Betaproteobacteria,2KN8J@206350|Nitrosomonadales 206350|Nitrosomonadales S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N DYD3_k127_4556264_1 1232683.ADIMK_0681 2.525e-219 691.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - Glutaredoxin,PALP DYD3_k127_4556264_3 1205680.CAKO01000002_gene2952 1.169e-43 167.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria,2JX0J@204441|Rhodospirillales 204441|Rhodospirillales I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydratas DYD3_k127_4556264_4 697282.Mettu_4100 2.283e-30 128.0 COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,1SEGZ@1236|Gammaproteobacteria,1XGGS@135618|Methylococcales 135618|Methylococcales S 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - - - - - - - - - - NTP_transf_3 DYD3_k127_4556264_2 325777.GW15_0204595 5.661e-51 186.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1SA8G@1236|Gammaproteobacteria,1XC86@135614|Xanthomonadales 135614|Xanthomonadales H Molybdopterin-converting factor chain 2 moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE DYD3_k127_4563646_8 187272.Mlg_0380 1.096e-52 195.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1WW48@135613|Chromatiales 135613|Chromatiales H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C DYD3_k127_4563646_9 287.DR97_3815 3.651e-30 124.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1YFSW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB DYD3_k127_4563646_7 314278.NB231_10118 5.626e-57 202.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,1WX65@135613|Chromatiales 135613|Chromatiales H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase DYD3_k127_4563646_1 1123256.KB907926_gene642 6.783e-147 474.0 COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,1X31N@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 DYD3_k127_4563646_5 768671.ThimaDRAFT_3346 5.167e-73 252.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1WXA6@135613|Chromatiales 135613|Chromatiales H riboflavin synthase, alpha subunit - - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding DYD3_k127_4563646_4 765911.Thivi_1032 2.5e-118 391.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales 135613|Chromatiales H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 DYD3_k127_4563646_6 322710.Avin_06700 1.3e-62 219.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone DYD3_k127_4563646_0 631362.Thi970DRAFT_04939 3.255e-206 653.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1WW0I@135613|Chromatiales 135613|Chromatiales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT DYD3_k127_4563646_3 1123368.AUIS01000007_gene2819 7.586e-121 396.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,2NCEM@225057|Acidithiobacillales 1236|Gammaproteobacteria BQ Histone deacetylase domain - - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl DYD3_k127_4563646_2 395493.BegalDRAFT_0585 2.277e-145 467.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales 72273|Thiotrichales S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn DYD3_k127_4565087_0 1260251.SPISAL_01535 1.188e-155 499.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1WXEN@135613|Chromatiales 135613|Chromatiales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM DYD3_k127_4565087_1 765911.Thivi_1325 3.016e-101 340.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,1WWN7@135613|Chromatiales 135613|Chromatiales OU PFAM peptidase - - - ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49,Peptidase_S49_N DYD3_k127_4565087_4 717774.Marme_1747 2.479e-69 244.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1XIXM@135619|Oceanospirillales 135619|Oceanospirillales O peptidase - - - - - - - - - - - - Peptidase_M48 DYD3_k127_4565087_3 1123393.KB891316_gene1481 9.893e-72 252.0 COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,2VRVY@28216|Betaproteobacteria,1KSWC@119069|Hydrogenophilales 119069|Hydrogenophilales Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 DYD3_k127_4565087_2 1123368.AUIS01000007_gene2702 9.167e-93 318.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,2NCX3@225057|Acidithiobacillales 225057|Acidithiobacillales S L,D-transpeptidase catalytic domain - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - LysM,YkuD DYD3_k127_4572084_4 1163398.AJJP01000167_gene1693 8.012e-06 50.0 COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,1RMYN@1236|Gammaproteobacteria 1236|Gammaproteobacteria M peptidase - - - - - - - - - - - - Peptidase_M23 DYD3_k127_4572084_2 187272.Mlg_0693 2.758e-117 393.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales 135613|Chromatiales L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 DYD3_k127_4572084_1 697282.Mettu_1869 1.387e-226 710.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XESH@135618|Methylococcales 135618|Methylococcales F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH DYD3_k127_4572084_0 1211114.ALIP01000128_gene1100 3.246e-246 769.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1X2YI@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase DYD3_k127_4572084_3 331869.BAL199_11546 2.803e-30 123.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TVAX@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Aminotran_5 DYD3_k127_4574640_1 1123073.KB899242_gene1477 7.868e-100 330.0 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales 135614|Xanthomonadales S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 DYD3_k127_4574640_0 1395571.TMS3_0110500 1.825e-114 377.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_4574640_2 1535422.ND16A_2677 4.606e-55 195.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,2Q5Z8@267889|Colwelliaceae 1236|Gammaproteobacteria E Gamma-glutamyltranspeptidase ggt_3 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD3_k127_4578714_1 565045.NOR51B_2247 1.142e-15 80.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T1MR@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_4578714_0 1265313.HRUBRA_00627 1.767e-187 596.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II alkK - 6.2.1.44 ko:K20034 ko00920,map00920 - R10820 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C DYD3_k127_4582931_3 1442599.JAAN01000019_gene2374 3.063e-13 69.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales 135614|Xanthomonadales I Acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD3_k127_4582931_0 313612.L8106_07796 8.732e-117 392.0 COG0534@1|root,COG0534@2|Bacteria,1G2M4@1117|Cyanobacteria,1H8IY@1150|Oscillatoriales 1117|Cyanobacteria V Mate efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD3_k127_4582931_1 1121374.KB891576_gene692 1.686e-37 143.0 COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,1RSM2@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the Nudix hydrolase family - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX DYD3_k127_4586065_0 1121374.KB891577_gene3209 4.9e-103 339.0 COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,1RY2R@1236|Gammaproteobacteria 1236|Gammaproteobacteria C COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C DYD3_k127_4612555_0 1122604.JONR01000016_gene4433 8.681e-175 567.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1X8HM@135614|Xanthomonadales 135614|Xanthomonadales T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - CHASE2,Guanylate_cyc DYD3_k127_4612555_1 87626.PTD2_03231 2.413e-41 169.0 COG0457@1|root,COG0457@2|Bacteria 87626.PTD2_03231|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - DYD3_k127_4628319_1 713586.KB900536_gene725 1.749e-221 694.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1WW4U@135613|Chromatiales 135613|Chromatiales L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB DYD3_k127_4628319_4 857087.Metme_1718 1.086e-64 226.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1XF2T@135618|Methylococcales 135618|Methylococcales J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N DYD3_k127_4628319_8 357804.Ping_2217 2.332e-18 87.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,2QIDF@267894|Psychromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p DYD3_k127_4628319_6 1336245.JAGO01000012_gene1858 4.653e-47 171.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1XJKA@135619|Oceanospirillales 135619|Oceanospirillales J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT - - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 DYD3_k127_4628319_2 1122201.AUAZ01000024_gene834 3.557e-134 434.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,465BM@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN746.PP_2469 Phe_tRNA-synt_N,tRNA-synt_2d DYD3_k127_4628319_0 391615.ABSJ01000059_gene2179 2.045e-225 722.0 COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1J4MP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_2160,iPC815.YPO2428 B3_4,B5,FDX-ACB,tRNA_bind DYD3_k127_4628319_7 1484157.PSNIH2_08870 1.094e-42 160.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,3W0TA@53335|Pantoea 1236|Gammaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding DYD3_k127_4628319_5 287.DR97_5225 4.255e-57 200.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1YG86@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K MerR family regulatory protein VL23_01195 - - - - - - - - - - - MerR_1 DYD3_k127_4628319_3 247634.GPB2148_2914 5.99e-95 326.0 28N0P@1|root,2ZB71@2|Bacteria,1R8S0@1224|Proteobacteria,1S0PI@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4628319_9 926550.CLDAP_38230 6.374e-11 66.0 COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi 200795|Chloroflexi E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C DYD3_k127_46436_1 391615.ABSJ01000026_gene121 1.358e-14 78.0 2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1J8X1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - - DYD3_k127_46436_0 1122194.AUHU01000003_gene2232 1.454e-61 227.0 COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,465KK@72275|Alteromonadaceae 1236|Gammaproteobacteria M COG0729 Outer membrane protein ytfM - - ko:K07278 - - - - ko00000,ko02000 1.B.33.2.4 - - Bac_surface_Ag,POTRA,POTRA_TamA_1 DYD3_k127_4653025_1 1353528.DT23_07450 3.389e-114 384.0 COG1807@1|root,COG1807@2|Bacteria,1PKMZ@1224|Proteobacteria,2V6GX@28211|Alphaproteobacteria,2XKPQ@285107|Thioclava 28211|Alphaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD3_k127_4653025_4 522306.CAP2UW1_0134 6.72e-13 73.0 2CHK6@1|root,333A9@2|Bacteria,1N9I7@1224|Proteobacteria,2VWH1@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4653025_0 497964.CfE428DRAFT_5240 9.776e-130 420.0 COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia 74201|Verrucomicrobia S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 DYD3_k127_4653025_3 1123377.AUIV01000012_gene700 1.113e-19 90.0 COG1872@1|root,COG1872@2|Bacteria 2|Bacteria I DUF167 CP_0257 - - ko:K09131 - - - - ko00000 - - - DUF167 DYD3_k127_4653025_2 1265505.ATUG01000001_gene4136 5.4e-33 133.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MCR@68525|delta/epsilon subdivisions,2WJXI@28221|Deltaproteobacteria,2MJD7@213118|Desulfobacterales 28221|Deltaproteobacteria EK Alanine-glyoxylate amino-transferase - - - - - - - - - - - - Aminotran_1_2 DYD3_k127_4661373_1 457424.BFAG_02335 5.032e-18 87.0 COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,2FVX3@200643|Bacteroidia 976|Bacteroidetes K transcriptional regulator pchR - - - - - - - - - - - HTH_18 DYD3_k127_4661373_0 317655.Sala_1463 1.226e-129 430.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,2U2KS@28211|Alphaproteobacteria,2KDKA@204457|Sphingomonadales 204457|Sphingomonadales P TonB-dependent receptor plug - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_4666922_2 472759.Nhal_0853 3.846e-40 153.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,1WXYI@135613|Chromatiales 135613|Chromatiales O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE - - ko:K02197 - - - - ko00000 - - - CcmE DYD3_k127_4666922_0 640081.Dsui_1172 4.327e-245 774.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,2KUNW@206389|Rhodocyclales 206389|Rhodocyclales O Cytochrome c ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm DYD3_k127_4666922_1 323848.Nmul_A1208 3.716e-52 192.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,372UU@32003|Nitrosomonadales 28216|Betaproteobacteria CO oxidoreductase DsbE dsbE - - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin DYD3_k127_4666922_4 1415778.JQMM01000001_gene2048 2.026e-29 123.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1J6GH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P subunit of a heme lyase ccmH GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - ko:K02200,ko:K04017 - - - - ko00000 - - - CcmH DYD3_k127_4666922_3 395493.BegalDRAFT_2396 2.562e-33 141.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,462SF@72273|Thiotrichales 72273|Thiotrichales O Tetratricopeptide repeat - - - - - - - - - - - - TPR_2 DYD3_k127_4666922_5 572479.Hprae_0601 1.478e-12 69.0 COG2050@1|root,COG2050@2|Bacteria,1V824@1239|Firmicutes,24R76@186801|Clostridia,3WAU7@53433|Halanaerobiales 186801|Clostridia Q PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT DYD3_k127_468640_2 1122604.JONR01000017_gene4299 7.314e-31 133.0 COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,1RQGS@1236|Gammaproteobacteria,1X35X@135614|Xanthomonadales 135614|Xanthomonadales Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 DYD3_k127_468640_0 876044.IMCC3088_2132 3.513e-190 603.0 COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria,1J7PK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 DYD3_k127_468640_1 1492922.GY26_19905 1.503e-31 126.0 COG2050@1|root,COG2050@2|Bacteria,1RHAN@1224|Proteobacteria,1S79C@1236|Gammaproteobacteria,1JA32@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 DYD3_k127_4693742_7 1149133.ppKF707_6134 5.101e-59 209.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1YDF1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_0142,iECSP_1301.ECSP_0134,iECs_1301.ECs0137,iG2583_1286.G2583_0137,iZ_1308.Z0144 Pantoate_ligase DYD3_k127_4693742_6 1112217.PPL19_17665 5.161e-67 241.0 COG2199@1|root,COG3706@2|Bacteria,1REIE@1224|Proteobacteria,1SPFU@1236|Gammaproteobacteria 1236|Gammaproteobacteria T cyclic nucleotide-binding protein - - - - - - - - - - - - GGDEF,cNMP_binding DYD3_k127_4693742_1 857087.Metme_2592 1.093e-152 490.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1XEPK@135618|Methylococcales 135618|Methylococcales C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 DYD3_k127_4693742_2 396588.Tgr7_0892 1.471e-149 488.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1WW1V@135613|Chromatiales 135613|Chromatiales G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N DYD3_k127_4693742_9 1279015.KB908463_gene2067 1.908e-33 142.0 COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1Y4H6@135624|Aeromonadales 135624|Aeromonadales S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE DYD3_k127_4693742_4 2340.JV46_15210 1.003e-125 418.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1J4PG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - iPC815.YPO1023,iSDY_1059.SDY_3034,iYL1228.KPN_03225 AMIN,Amidase_3,LysM DYD3_k127_4693742_0 713586.KB900536_gene2956 4.053e-206 656.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1WWKZ@135613|Chromatiales 135613|Chromatiales L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C DYD3_k127_4693742_5 1123073.KB899245_gene71 7.675e-96 323.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1X3TF@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT DYD3_k127_4693742_8 1336245.JAGO01000010_gene773 2.716e-35 139.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1XKET@135619|Oceanospirillales 135619|Oceanospirillales J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq DYD3_k127_4693742_3 2340.JV46_15160 1.053e-143 468.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1J4RK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 DYD3_k127_4693742_10 1049564.TevJSym_bl00180 3.776e-33 132.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1J4H5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N DYD3_k127_4769276_0 396588.Tgr7_3022 4.027e-122 407.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase DYD3_k127_4769276_1 349521.HCH_05972 5.145e-113 374.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1XH3V@135619|Oceanospirillales 135619|Oceanospirillales NU Pilus assembly protein pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 DYD3_k127_4769276_3 1283300.ATXB01000001_gene2122 8.161e-44 166.0 COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1XF1T@135618|Methylococcales 135618|Methylococcales NU PFAM Fimbrial assembly - - - ko:K02663 - - - - ko00000,ko02035,ko02044 - - - PilN DYD3_k127_4769276_2 396588.Tgr7_3026 1.57e-55 202.0 COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1WXKR@135613|Chromatiales 135613|Chromatiales NU Pilus assembly protein PilO - - - ko:K02664 - - - - ko00000,ko02035,ko02044 - - - PilO DYD3_k127_4809549_1 1500257.JQNM01000001_gene3364 1.129e-06 53.0 COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,2TQUT@28211|Alphaproteobacteria,4BD1H@82115|Rhizobiaceae 28211|Alphaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD3_k127_4809549_0 314285.KT71_03017 4.981e-79 286.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1RWT6@1236|Gammaproteobacteria,1J7Y7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - DYD3_k127_4828912_5 466088.CL42_04680 1.479e-26 110.0 COG0671@1|root,COG0671@2|Bacteria,1RHGF@1224|Proteobacteria,1S8K3@1236|Gammaproteobacteria,3NJTU@468|Moraxellaceae 1236|Gammaproteobacteria I Acid phosphatase homologues - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 DYD3_k127_4828912_1 566466.NOR53_491 3.478e-85 309.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C DYD3_k127_4828912_2 639283.Snov_1608 1.104e-67 241.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,3EZ9N@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gloA GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase DYD3_k127_4828912_4 395493.BegalDRAFT_1818 7.218e-56 203.0 COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Hydrolase yigB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104 ko:K20862 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - HAD_2 DYD3_k127_4828912_3 580332.Slit_2150 8.811e-67 238.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - DYD3_k127_4828912_0 377629.TERTU_0906 3.892e-87 306.0 COG2885@1|root,COG2885@2|Bacteria,1P1AB@1224|Proteobacteria,1RMCQ@1236|Gammaproteobacteria,2PQ00@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria M OmpA family oprF - - - - - - - - - - - OmpA DYD3_k127_4831961_1 1121920.AUAU01000005_gene929 4.409e-53 196.0 COG0451@1|root,COG0451@2|Bacteria,3Y95U@57723|Acidobacteria 57723|Acidobacteria GM NAD dependent epimerase/dehydratase family - - - - - - - - - - - - Epimerase DYD3_k127_4831961_0 713586.KB900536_gene2148 1.972e-65 229.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria 1236|Gammaproteobacteria D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA DYD3_k127_4831961_3 713586.KB900536_gene2181 5.346e-43 166.0 COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales 135613|Chromatiales S Protein of unknown function, DUF484 - - - ko:K09921 - - - - ko00000 - - - DUF484 DYD3_k127_4831961_2 396588.Tgr7_0047 1.49e-48 186.0 COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1WW4W@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase DYD3_k127_4839605_3 1250005.PHEL85_0342 2.837e-30 125.0 2C7KN@1|root,32RJD@2|Bacteria,4NR1V@976|Bacteroidetes,1I42C@117743|Flavobacteriia,3VWWW@52959|Polaribacter 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_4839605_0 1232437.KL662001_gene4588 4.717e-77 263.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales 28221|Deltaproteobacteria L DNA-3-methyladenine glycosylase I tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco DYD3_k127_4839605_4 1117314.PCIT_15720 1.735e-15 82.0 COG3767@1|root,COG3767@2|Bacteria,1N9HK@1224|Proteobacteria,1SD4Q@1236|Gammaproteobacteria,2Q1NP@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_4839605_5 382245.ASA_2155 9.794e-13 78.0 COG5662@1|root,COG5662@2|Bacteria,1RJ4M@1224|Proteobacteria,1S23M@1236|Gammaproteobacteria,1Y5QX@135624|Aeromonadales 135624|Aeromonadales K Protein of unknown function (DUF3379) - - - - - - - - - - - - DUF3379 DYD3_k127_4839605_2 1056512.D515_00719 5.774e-43 163.0 COG1595@1|root,COG1595@2|Bacteria,1R9ZN@1224|Proteobacteria,1S27W@1236|Gammaproteobacteria,1Y2D5@135623|Vibrionales 135623|Vibrionales K Belongs to the sigma-70 factor family. ECF subfamily sigV - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_4839605_1 1397528.Q671_11320 1.725e-63 224.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1XI8U@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD DYD3_k127_4849973_0 713586.KB900536_gene1207 1.538e-94 316.0 COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,1S2PS@1236|Gammaproteobacteria 1236|Gammaproteobacteria O methyltransferase activity - - 2.1.1.334 ko:K21310 ko00920,map00920 - R11546 RC02653 ko00000,ko00001,ko01000 - - - NnrU,PEMT DYD3_k127_4849973_1 1288083.AUKR01000014_gene2873 9.596e-23 114.0 COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria 201174|Actinobacteria IK Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Trans_reg_C DYD3_k127_4849973_2 56110.Oscil6304_5731 1.142e-13 85.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales 1117|Cyanobacteria U Tetratricopeptide repeat - - - - - - - - - - - - CHAT,TPR_12,TPR_7,TPR_8 DYD3_k127_4850020_0 566466.NOR53_592 1.23e-292 914.0 COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria 1236|Gammaproteobacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 DYD3_k127_4854275_4 935557.ATYB01000010_gene347 2.255e-31 126.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,4B765@82115|Rhizobiaceae 28211|Alphaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase DYD3_k127_4854275_2 469383.Cwoe_2725 7.01e-56 198.0 COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,4CTCG@84995|Rubrobacteria 84995|Rubrobacteria P Ferric uptake regulator family - - - ko:K22297 - - - - ko00000,ko03000 - - - FUR DYD3_k127_4854275_1 1121123.AUAO01000001_gene638 2.462e-81 275.0 COG1309@1|root,COG1309@2|Bacteria,1RGCX@1224|Proteobacteria,2UEW7@28211|Alphaproteobacteria,2KI8Q@204458|Caulobacterales 204458|Caulobacterales K Bacterial transcriptional repressor C-terminal - - - - - - - - - - - - TetR_C_13,TetR_N DYD3_k127_4854275_3 1282360.ABAC460_16250 3.643e-49 179.0 29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,2UKUZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 DYD3_k127_4854275_5 1122604.JONR01000042_gene3451 6.243e-27 120.0 2EBUX@1|root,335UE@2|Bacteria,1NAYE@1224|Proteobacteria,1T8Q1@1236|Gammaproteobacteria,1XB2A@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_4854275_0 1120951.AUBG01000012_gene1544 9.153e-88 306.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,HTH_18,TPR_8 DYD3_k127_4865465_4 997346.HMPREF9374_3957 1.265e-41 156.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HE2X@91061|Bacilli,27BYJ@186824|Thermoactinomycetaceae 91061|Bacilli S Possible lysine decarboxylase yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox DYD3_k127_4865465_2 247633.GP2143_09475 1.239e-72 250.0 COG2236@1|root,COG2236@2|Bacteria,1MXS1@1224|Proteobacteria,1RPSD@1236|Gammaproteobacteria 1236|Gammaproteobacteria F phosphoribosyltransferase - - - ko:K07101 - - - - ko00000 - - - Pribosyltran DYD3_k127_4865465_3 314285.KT71_03272 9.009e-63 222.0 COG2236@1|root,COG2236@2|Bacteria,1RAZS@1224|Proteobacteria,1S2IG@1236|Gammaproteobacteria,1J8J2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Phosphoribosyl transferase domain - - - ko:K07101 - - - - ko00000 - - - Pribosyltran DYD3_k127_4865465_0 748247.AZKH_3279 7.211e-163 524.0 COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,2VJN1@28216|Betaproteobacteria,2KUIT@206389|Rhodocyclales 206389|Rhodocyclales F COG0402 Cytosine deaminase and related metal-dependent hydrolases guaD - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 DYD3_k127_4865465_5 748280.NH8B_0261 3.057e-40 157.0 COG3194@1|root,COG3194@2|Bacteria,1RH5G@1224|Proteobacteria,2VT31@28216|Betaproteobacteria,2KSXA@206351|Neisseriales 206351|Neisseriales F Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source allA - 4.3.2.3 ko:K01483 ko00230,ko01100,map00230,map01100 - R00776 RC00153,RC00379 ko00000,ko00001,ko01000 - - - Ureidogly_lyase DYD3_k127_4865465_1 1056512.D515_04189 2.594e-129 421.0 COG4266@1|root,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,1RR90@1236|Gammaproteobacteria,1XUHG@135623|Vibrionales 135623|Vibrionales F Belongs to the allantoicase family alc - 3.5.3.4 ko:K01477 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R02422 RC00379,RC00712 ko00000,ko00001,ko00002,ko01000 - - - Allantoicase DYD3_k127_4865465_6 1196835.A458_05175 1.152e-39 151.0 COG3195@1|root,COG3195@2|Bacteria,1RH9S@1224|Proteobacteria,1S25P@1236|Gammaproteobacteria,1Z19R@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S protein conserved in bacteria uraD - - - - - - - - - - - OHCU_decarbox DYD3_k127_4865596_4 1217718.ALOU01000007_gene1258 8.88e-39 153.0 COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2W0N2@28216|Betaproteobacteria 28216|Betaproteobacteria O PPIC-type PPIASE domain - - - - - - - - - - - - Rotamase_2 DYD3_k127_4865596_1 1217718.ALOU01000007_gene1259 1.346e-95 325.0 COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2VM5U@28216|Betaproteobacteria,1KF02@119060|Burkholderiaceae 28216|Betaproteobacteria O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 DYD3_k127_4865596_0 583355.Caka_1487 2.407e-175 573.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec DYD3_k127_4865596_2 566466.NOR53_2707 6.017e-40 156.0 2E5SP@1|root,330H2@2|Bacteria,1NDBY@1224|Proteobacteria 1224|Proteobacteria S YMGG-like Gly-zipper - - - - - - - - - - - - Gly-zipper_OmpA,Gly-zipper_YMGG DYD3_k127_4865596_3 1283300.ATXB01000001_gene392 7.076e-40 148.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 DYD3_k127_4870218_3 1163617.SCD_n01097 1.597e-68 241.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria 28216|Betaproteobacteria M lipoprotein releasing system, transmembrane protein, LolC E family lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD DYD3_k127_4870218_0 1123261.AXDW01000001_gene1446 2.524e-133 437.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1X2ZV@135614|Xanthomonadales 135614|Xanthomonadales M Lipoprotein releasing system transmembrane protein lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD DYD3_k127_4870218_2 1122603.ATVI01000008_gene2454 1.909e-83 285.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1X2X9@135614|Xanthomonadales 135614|Xanthomonadales V Part of the ABC transporter complex LolCDE involved in the translocation of lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran DYD3_k127_4870218_4 523791.Kkor_1382 2.859e-39 152.0 COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1XJZU@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K09928 - - - - ko00000 - - - DUF2062 DYD3_k127_4870218_1 472759.Nhal_0530 3.999e-107 372.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales 135613|Chromatiales S DNA internalization-related competence protein ComEC Rec2 - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B DYD3_k127_487816_1 1044.EH31_10935 2.452e-10 69.0 COG0803@1|root,COG0803@2|Bacteria,1R91T@1224|Proteobacteria,2TRDQ@28211|Alphaproteobacteria,2K7HG@204457|Sphingomonadales 204457|Sphingomonadales P ChrR Cupin-like domain - - - - - - - - - - - - Cupin_7 DYD3_k127_487816_0 1122134.KB893650_gene584 8.796e-287 895.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1XP2X@135619|Oceanospirillales 135619|Oceanospirillales S OPT oligopeptide transporter protein - - - - - - - - - - - - OPT DYD3_k127_489015_0 593105.S7A_05460 6.84e-115 386.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,3VYXQ@53335|Pantoea 1236|Gammaproteobacteria H Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - iPC815.YPO2896,iYL1228.KPN_02862 Aminotran_5 DYD3_k127_489015_2 1123368.AUIS01000004_gene248 3.758e-80 274.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,2NBQP@225057|Acidithiobacillales 225057|Acidithiobacillales J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA trmJ - 2.1.1.200 ko:K15396 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase DYD3_k127_489015_1 187272.Mlg_1244 6.484e-96 320.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales 135613|Chromatiales G Inositol monophosphatase - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P DYD3_k127_4891593_0 65071.PYU1_T001079 4.684e-228 732.0 COG0265@1|root,KOG1421@2759|Eukaryota,1MAFU@121069|Pythiales 121069|Pythiales O Pro-apoptotic serine protease - - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 DYD3_k127_4898921_3 760117.JN27_13060 2.137e-82 279.0 COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2WENQ@28216|Betaproteobacteria,472E8@75682|Oxalobacteraceae 28216|Betaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 DYD3_k127_4898921_5 1144342.PMI40_01437 2.25e-48 191.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,4762B@75682|Oxalobacteraceae 28216|Betaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg DYD3_k127_4898921_4 1120983.KB894575_gene528 8.545e-71 257.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,1JPNG@119043|Rhodobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9,Response_reg,sCache_2 DYD3_k127_4898921_0 1283300.ATXB01000001_gene1641 2.196e-108 360.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,1XEIQ@135618|Methylococcales 135618|Methylococcales P Cation efflux family - - - - - - - - - - - - Cation_efflux DYD3_k127_4898921_2 1121939.L861_15500 2.137e-89 302.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1XI57@135619|Oceanospirillales 135619|Oceanospirillales M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix DYD3_k127_4898921_1 1265313.HRUBRA_01348 1.09e-100 347.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - DUF222,HNH DYD3_k127_4902675_4 536019.Mesop_5669 1.569e-23 105.0 COG3791@1|root,COG3791@2|Bacteria 2|Bacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA DYD3_k127_4902675_1 243233.MCA1000 2.422e-67 239.0 2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales 135618|Methylococcales S Ceramidase - - - - - - - - - - - - Ceramidase DYD3_k127_4902675_2 29581.BW37_03878 4.893e-32 133.0 2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_4902675_3 392499.Swit_0205 5.569e-32 128.0 COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria,2UFSH@28211|Alphaproteobacteria,2KBHV@204457|Sphingomonadales 204457|Sphingomonadales G Cupin domain - - - - - - - - - - - - Cupin_2 DYD3_k127_4902675_0 667632.KB890164_gene2153 2.23e-131 430.0 COG0436@1|root,COG0436@2|Bacteria,1R4E6@1224|Proteobacteria,2W0Y0@28216|Betaproteobacteria,1K6GM@119060|Burkholderiaceae 28216|Betaproteobacteria E Cys/Met metabolism PLP-dependent enzyme - - - - - - - - - - - - Aminotran_1_2 DYD3_k127_4902675_5 1321778.HMPREF1982_02132 1.657e-06 51.0 2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD3_k127_4912228_1 523791.Kkor_2383 5.376e-126 414.0 COG1404@1|root,COG1404@2|Bacteria,1QYT6@1224|Proteobacteria,1T3TK@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Domain of unknown function (DUF4397) - - - - - - - - - - - - CHRD,DUF4397 DYD3_k127_4912228_0 472759.Nhal_0304 2.196e-132 431.0 COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1WWIX@135613|Chromatiales 135613|Chromatiales M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS DYD3_k127_4912228_5 768671.ThimaDRAFT_4663 1.908e-33 142.0 2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,1SCY7@1236|Gammaproteobacteria,1WYDM@135613|Chromatiales 135613|Chromatiales S Protein of unknown function (DUF2878) - - - - - - - - - - - - DUF2878 DYD3_k127_4912228_2 1458275.AZ34_07550 5.37e-94 314.0 COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2VQHY@28216|Betaproteobacteria,4ADH5@80864|Comamonadaceae 28216|Betaproteobacteria S 3-oxo-5-alpha-steroid 4-dehydrogenase - - - - - - - - - - - - DUF1295 DYD3_k127_4912228_4 1458275.AZ34_07545 6.973e-43 176.0 COG4338@1|root,COG4338@2|Bacteria,1N3G5@1224|Proteobacteria,2VUMZ@28216|Betaproteobacteria,4AF09@80864|Comamonadaceae 28216|Betaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - DYD3_k127_4912228_3 1026882.MAMP_02439 2.089e-76 259.0 COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,1T0AA@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Outer Membrane Lipoprotein blc4 - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 DYD3_k127_4912228_6 472759.Nhal_0309 7.515e-26 121.0 COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1RP4P@1236|Gammaproteobacteria,1WWBX@135613|Chromatiales 135613|Chromatiales S PFAM Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase DYD3_k127_4924724_1 1089551.KE386572_gene1832 1.842e-130 439.0 COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,2TT69@28211|Alphaproteobacteria,4BRI0@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Glucose inhibited division protein A - - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO DYD3_k127_4924724_0 1454004.AW11_00371 9.986e-297 938.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VJ23@28216|Betaproteobacteria 28216|Betaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran DYD3_k127_4933051_5 1283300.ATXB01000002_gene2887 2.12e-104 348.0 COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome C family protein - - - - - - - - - - - - Cytochrome_C554,Paired_CXXCH_1 DYD3_k127_4933051_8 326297.Sama_1206 1.629e-79 291.0 COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria,2QA00@267890|Shewanellaceae 1236|Gammaproteobacteria M Putative outer membrane beta-barrel porin, MtrB/PioB - - - - - - - - - - - - MtrB_PioB DYD3_k127_4933051_9 870187.Thini_0772 3.63e-66 235.0 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,1RPJA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S integral membrane protein - - - - - - - - - - - - DUF2189 DYD3_k127_4933051_0 1123073.KB899241_gene3481 2.412e-255 792.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1X3WE@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the heme-copper respiratory oxidase family - - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 DYD3_k127_4933051_6 1198232.CYCME_1842 1.932e-92 307.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales 72273|Thiotrichales C TIGRFAM cytochrome c oxidase, cbb3-type, subunit II - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO DYD3_k127_4933051_13 1178482.BJB45_02705 9.948e-11 65.0 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ DYD3_k127_4933051_7 2340.JV46_10170 3.877e-90 306.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1J545@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - iJN746.PP_4253 Cytochrome_CBB3,FixP_N DYD3_k127_4933051_15 1384054.N790_02795 6.552e-06 54.0 2EFX9@1|root,339PI@2|Bacteria,1NI0D@1224|Proteobacteria,1SGKH@1236|Gammaproteobacteria,1X7EB@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_4933051_3 187272.Mlg_1877 3.27e-178 571.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,1WWVW@135613|Chromatiales 135613|Chromatiales C TIGRFAM cytochrome c oxidase accessory protein - - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C DYD3_k127_4933051_14 1072685.IX83_02535 1.901e-07 54.0 COG3198@1|root,COG3198@2|Bacteria,1PTX2@1224|Proteobacteria,2WDKR@28216|Betaproteobacteria,3T4YQ@506|Alcaligenaceae 28216|Betaproteobacteria S FixH - - - ko:K09926 - - - - ko00000 - - - FixH DYD3_k127_4933051_2 2340.JV46_28240 6.626e-187 612.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J595@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P cation transport ATPase ccoI - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase DYD3_k127_4933051_12 1397528.Q671_03770 7.043e-13 73.0 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,1XMBA@135619|Oceanospirillales 135619|Oceanospirillales P Cytochrome oxidase maturation protein - - - - - - - - - - - - FixS DYD3_k127_4933051_11 396588.Tgr7_2923 9.911e-42 163.0 COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1WXWD@135613|Chromatiales 135613|Chromatiales S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 DYD3_k127_4933051_4 204669.Acid345_1633 2.438e-171 564.0 COG0665@1|root,COG0665@2|Bacteria 2|Bacteria E tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - 1.5.99.6 ko:K00316 ko00330,ko00410,ko01100,map00330,map00410,map01100 - R01914,R01915 RC00053,RC00225 ko00000,ko00001,ko01000 - - - DAO,FAD_oxidored,NAD_binding_8 DYD3_k127_4933051_1 247634.GPB2148_2931 6.524e-231 724.0 COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,1RMAI@1236|Gammaproteobacteria,1J7IF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H AbgT putative transporter family abgT - - ko:K12942 - - - - ko00000 - - - ABG_transport DYD3_k127_4933051_10 999611.KI421504_gene673 2.432e-51 189.0 COG4312@1|root,COG4312@2|Bacteria,1QIBA@1224|Proteobacteria,2TTFP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF899) - - - - - - - - - - - - DUF899 DYD3_k127_4933425_1 1027273.GZ77_20955 7.524e-111 367.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1XH2Q@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV DYD3_k127_4933425_3 472759.Nhal_3702 6.035e-87 294.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1WW6U@135613|Chromatiales 135613|Chromatiales G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM DYD3_k127_4933425_6 396588.Tgr7_0985 1.113e-21 100.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,1WZFD@135613|Chromatiales 135613|Chromatiales U PFAM Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG DYD3_k127_4933425_5 317025.Tcr_0817 6.179e-50 180.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria,460WP@72273|Thiotrichales 72273|Thiotrichales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 DYD3_k127_4933425_2 637390.AFOH01000122_gene404 1.985e-95 314.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,2NBQJ@225057|Acidithiobacillales 225057|Acidithiobacillales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 DYD3_k127_4933425_4 472759.Nhal_3698 3.025e-81 276.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,1WWDD@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa DYD3_k127_4933425_0 472759.Nhal_3697 4.261e-124 400.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa DYD3_k127_49343_1 59196.RICGR_0663 3.866e-95 316.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RSN1@1236|Gammaproteobacteria,1JD1I@118969|Legionellales 118969|Legionellales I Fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - DDE_Tnp_ISL3,FA_desaturase DYD3_k127_49343_0 1245471.PCA10_02510 3.1e-106 351.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1YDZC@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD3_k127_49343_3 396588.Tgr7_0298 4.922e-58 208.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1WY42@135613|Chromatiales 135613|Chromatiales H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD3_k127_49343_4 305900.GV64_05220 5.22e-52 191.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1XK6E@135619|Oceanospirillales 135619|Oceanospirillales L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 DYD3_k127_49343_2 519989.ECTPHS_06612 9.69e-93 312.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1WW5G@135613|Chromatiales 135613|Chromatiales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N DYD3_k127_4946374_4 1249627.D779_3464 2.436e-09 59.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1WYID@135613|Chromatiales 135613|Chromatiales J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 DYD3_k127_4946374_1 713586.KB900536_gene2920 4.38e-96 320.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1WWK4@135613|Chromatiales 135613|Chromatiales J Belongs to the RNA methyltransferase TrmD family trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT DYD3_k127_4946374_2 351348.Maqu_2279 4.011e-45 173.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,467CY@72275|Alteromonadaceae 1236|Gammaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM DYD3_k127_4946374_3 1122201.AUAZ01000004_gene3354 7.951e-28 124.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,467U2@72275|Alteromonadaceae 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 DYD3_k127_4946374_0 1335757.SPICUR_07135 2.494e-97 323.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1WW6N@135613|Chromatiales 135613|Chromatiales U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB DYD3_k127_4962571_3 1123261.AXDW01000019_gene720 2.741e-18 86.0 COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,1RR21@1236|Gammaproteobacteria,1X4SX@135614|Xanthomonadales 135614|Xanthomonadales I Acyltransferase - - - - - - - - - - - - Acyltransferase DYD3_k127_4962571_2 572480.Arnit_1444 2.733e-20 94.0 COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2YQ7S@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG DYD3_k127_4962571_1 391615.ABSJ01000037_gene928 5.172e-56 209.0 COG2220@1|root,COG2220@2|Bacteria,1RGMH@1224|Proteobacteria,1S8AS@1236|Gammaproteobacteria,1JADA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Zn-dependent hydrolases of the beta-lactamase fold - - - - - - - - - - - - Lactamase_B,Lactamase_B_2 DYD3_k127_4962571_0 1121938.AUDY01000011_gene788 9.995e-70 250.0 COG5505@1|root,COG5505@2|Bacteria,1TSC8@1239|Firmicutes,4HEAJ@91061|Bacilli,3NFYA@45667|Halobacillus 91061|Bacilli S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 DYD3_k127_4981191_0 1122137.AQXF01000005_gene1249 0.0 1408.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Formate dehydrogenase, alpha subunit - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_6,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD3_k127_4981191_1 1415755.JQLV01000001_gene3655 6.963e-72 244.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1XH7K@135619|Oceanospirillales 135619|Oceanospirillales C NADH-quinone oxidoreductase subunit F fdsB - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Complex1_51K,NADH_4Fe-4S,SLBB DYD3_k127_4998533_2 1282876.BAOK01000001_gene3578 5.995e-65 227.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2TW0G@28211|Alphaproteobacteria,4BTG2@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Reductase C-terminal - - 1.18.1.3 ko:K00529 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,Pyr_redox_2,Reductase_C,Rieske DYD3_k127_4998533_4 666509.RCA23_c30630 7.226e-59 214.0 2C3PP@1|root,2Z954@2|Bacteria,1MXGR@1224|Proteobacteria,2TS01@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Branched-chain amino acid aminotransferase - - - - - - - - - - - - - DYD3_k127_4998533_1 85681.XP_006433174.1 1.755e-107 359.0 COG0115@1|root,KOG2497@1|root,KOG0975@2759|Eukaryota,KOG2497@2759|Eukaryota,37P5K@33090|Viridiplantae,3G79E@35493|Streptophyta 35493|Streptophyta E branched-chain-amino-acid aminotransferase-like protein - - - - - - - - - - - - Aminotran_4,Methyltransf_16 DYD3_k127_4998533_0 236097.ADG881_2668 1.712e-167 541.0 COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1XI43@135619|Oceanospirillales 135619|Oceanospirillales H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase DYD3_k127_4998533_6 338963.Pcar_1494 1.699e-11 72.0 2EKQ7@1|root,33EDZ@2|Bacteria,1NHK0@1224|Proteobacteria,42WYF@68525|delta/epsilon subdivisions,2WSKJ@28221|Deltaproteobacteria,43VUS@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF2845) - - - - - - - - - - - - DUF2845 DYD3_k127_4998533_5 1122925.KB895378_gene2453 1.374e-11 70.0 COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,4HNC2@91061|Bacilli,26XID@186822|Paenibacillaceae 91061|Bacilli M Integral membrane protein CcmA involved in cell shape determination - - - - - - - - - - - - Bactofilin DYD3_k127_4998533_3 247633.GP2143_08469 2.924e-60 226.0 COG2199@1|root,COG3706@2|Bacteria,1QVPW@1224|Proteobacteria,1T2GC@1236|Gammaproteobacteria,1JAKM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD3_k127_4998533_8 420662.Mpe_A2858 4.497e-05 54.0 COG0784@1|root,COG2198@1|root,COG3850@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3850@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,1KPMM@119065|unclassified Burkholderiales 28216|Betaproteobacteria T histidine kinase A domain protein - - - - - - - - - - - - CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg DYD3_k127_5002760_1 247634.GPB2148_1738 3.692e-119 390.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,1RQB7@1236|Gammaproteobacteria,1J5T1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E COG1177 ABC-type spermidine putrescine transport system, permease component II potI - - ko:K11074 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 DYD3_k127_5002760_2 247634.GPB2148_1802 5.532e-112 368.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1J5HM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E ABC-type spermidine putrescine transport system, permease component I potH GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11075 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - iAF1260.b0856,iBWG_1329.BWG_0709,iE2348C_1286.E2348C_0853,iECDH10B_1368.ECDH10B_0926,iECDH1ME8569_1439.ECDH1ME8569_0808,iEcDH1_1363.EcDH1_2786,iJO1366.b0856,iJR904.b0856,iY75_1357.Y75_RS04455 BPD_transp_1 DYD3_k127_5002760_0 247634.GPB2148_1755 3.319e-139 451.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1JBUJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - - ko:K11076 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - ABC_tran,TOBE_2 DYD3_k127_5002760_3 247634.GPB2148_1766 3.726e-71 246.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1J4HX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Required for the activity of the bacterial periplasmic transport system of putrescine potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 DYD3_k127_5030168_0 1040989.AWZU01000001_gene5816 1.495e-130 429.0 COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,3JUPG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 DYD3_k127_5030168_1 627192.SLG_12710 3.373e-32 128.0 COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2TTWF@28211|Alphaproteobacteria,2K2II@204457|Sphingomonadales 204457|Sphingomonadales C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD3_k127_5050496_0 414684.RC1_1744 2.021e-119 390.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2JQCM@204441|Rhodospirillales 204441|Rhodospirillales I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD3_k127_5050496_2 998674.ATTE01000001_gene3420 1.627e-45 171.0 COG1309@1|root,COG1309@2|Bacteria,1N6HV@1224|Proteobacteria,1SBC8@1236|Gammaproteobacteria 1236|Gammaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_C_2,TetR_C_6,TetR_N DYD3_k127_5050496_1 693986.MOC_0063 6.536e-78 268.0 COG1028@1|root,COG1028@2|Bacteria,1MXWI@1224|Proteobacteria,2TQQ6@28211|Alphaproteobacteria,1JSGW@119045|Methylobacteriaceae 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 DYD3_k127_5050496_3 252305.OB2597_11151 2.995e-11 70.0 COG2050@1|root,COG2050@2|Bacteria,1MZB4@1224|Proteobacteria,2U9Y0@28211|Alphaproteobacteria,2PE83@252301|Oceanicola 28211|Alphaproteobacteria Q Thioesterase superfamily - - - - - - - - - - - - 4HBT DYD3_k127_5050496_4 857087.Metme_3571 1.771e-06 49.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,1S2Y7@1236|Gammaproteobacteria,1XG6U@135618|Methylococcales 135618|Methylococcales O Redoxin - - - - - - - - - - - - AhpC-TSA DYD3_k127_5051532_0 1384056.N787_08615 6.151e-173 558.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1X486@135614|Xanthomonadales 135614|Xanthomonadales I 3-hydroxyacyl-coa dehydrogenase fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 DYD3_k127_5051532_1 391615.ABSJ01000026_gene110 1.275e-107 358.0 COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria PT COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - Rhodanese,cNMP_binding DYD3_k127_5051532_3 1123261.AXDW01000004_gene2877 9.383e-49 178.0 COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1X6W7@135614|Xanthomonadales 135614|Xanthomonadales NU Pilus assembly protein PilZ pilZ - - ko:K02676 - - - - ko00000,ko02035,ko02044 - - - PilZ DYD3_k127_5051532_4 243233.MCA1995 6.442e-43 170.0 COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1XDVJ@135618|Methylococcales 135618|Methylococcales L DNA polymerase III, delta' holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C DYD3_k127_5051532_2 1049564.TevJSym_bc00200 8.697e-56 199.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,1J5UI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin DYD3_k127_5086571_1 580332.Slit_0145 2.372e-57 206.0 COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales 28216|Betaproteobacteria J S-adenosylmethionine-dependent methyltransferase rlmI - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM DYD3_k127_5086571_0 452637.Oter_1405 3.374e-103 351.0 COG1368@1|root,COG1368@2|Bacteria,46U99@74201|Verrucomicrobia 74201|Verrucomicrobia M Sulfatase - - - - - - - - - - - - Sulfatase DYD3_k127_5140301_9 1304275.C41B8_11825 4.415e-90 299.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0050896,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 DYD3_k127_5140301_17 252305.OB2597_12331 2.336e-37 153.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,2PDY0@252301|Oceanicola 28211|Alphaproteobacteria L NUDIX domain MA20_44635 - - - - - - - - - - - NUDIX DYD3_k127_5140301_12 243233.MCA0046 7.903e-84 285.0 COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,1RNVU@1236|Gammaproteobacteria,1XEHR@135618|Methylococcales 135618|Methylococcales S MazG nucleotide pyrophosphohydrolase domain - - 3.6.1.9 ko:K04765 ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100 - R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323 RC00002 ko00000,ko00001,ko01000 - - - MazG DYD3_k127_5140301_19 1122603.ATVI01000007_gene1657 2.812e-29 124.0 COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,1RQR9@1236|Gammaproteobacteria,1X628@135614|Xanthomonadales 135614|Xanthomonadales S Outer membrane lipoprotein - - - - - - - - - - - - Rick_17kDa_Anti DYD3_k127_5140301_20 1234364.AMSF01000010_gene560 1.613e-05 51.0 2A9QK@1|root,30YXS@2|Bacteria,1QBJS@1224|Proteobacteria,1T75C@1236|Gammaproteobacteria,1X8T5@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_5140301_8 1121015.N789_13515 7.778e-95 317.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1X2XT@135614|Xanthomonadales 135614|Xanthomonadales KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K07660 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C DYD3_k127_5140301_11 765911.Thivi_4336 1.983e-86 303.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1X2PK@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c DYD3_k127_5140301_7 765912.Thimo_3321 3.397e-103 341.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1WX9J@135613|Chromatiales 135613|Chromatiales O PFAM Band 7 protein - - - - - - - - - - - - Band_7 DYD3_k127_5140301_6 314278.NB231_00740 2.458e-125 417.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1WXRD@135613|Chromatiales 135613|Chromatiales O NfeD-like C-terminal, partner-binding - - - ko:K07403 - - - - ko00000 - - - NfeD DYD3_k127_5140301_15 745014.OMB55_00020300 4.877e-57 203.0 COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,1S5WS@1236|Gammaproteobacteria,1J6RP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D VL23_12675 - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase DYD3_k127_5140301_2 522373.Smlt2132 1.512e-210 668.0 COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,1RY9G@1236|Gammaproteobacteria,1X3B2@135614|Xanthomonadales 135614|Xanthomonadales C belongs to the aldehyde dehydrogenase family - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD3_k127_5140301_5 1122165.AUHS01000001_gene1290 1.7e-138 454.0 COG1748@1|root,COG1748@2|Bacteria,1MY1G@1224|Proteobacteria,1RRUZ@1236|Gammaproteobacteria,1JD4N@118969|Legionellales 118969|Legionellales E Saccharopine dehydrogenase C-terminal domain lysDH - - - - - - - - - - - Sacchrp_dh_C,Sacchrp_dh_NADP DYD3_k127_5140301_3 1123256.KB907934_gene2402 3.479e-193 612.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,1X2YX@135614|Xanthomonadales 135614|Xanthomonadales E phospho-2-dehydro-3-deoxyheptonate aldolase dhs1 - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 DYD3_k127_5140301_13 1112217.PPL19_17845 2.972e-68 238.0 COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,1S1ZX@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluE - 5.4.99.20,5.4.99.22 ko:K06178,ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 DYD3_k127_5140301_0 1128421.JAGA01000004_gene2610 1.44e-220 696.0 COG2225@1|root,COG2225@2|Bacteria 2|Bacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA aceB GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010 Malate_synthase DYD3_k127_5140301_4 391615.ABSJ01000026_gene84 2.049e-192 609.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1J4Z7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Isocitrate icd GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 Iso_dh DYD3_k127_5140301_10 2340.JV46_03800 1.533e-86 291.0 COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,1S2B6@1236|Gammaproteobacteria 1236|Gammaproteobacteria L uracil-DNA glycosylase - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG DYD3_k127_5140301_1 314278.NB231_01574 3.504e-214 681.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales 135613|Chromatiales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N DYD3_k127_5140301_16 1415779.JOMH01000001_gene2918 4.287e-56 205.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1X300@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf DYD3_k127_5140301_18 565045.NOR51B_1340 2.589e-31 129.0 COG2010@1|root,COG2010@2|Bacteria,1N8E4@1224|Proteobacteria 1224|Proteobacteria C Cytochrome c - - - - - - - - - - - - - DYD3_k127_5140301_14 565045.NOR51B_1167 3.63e-62 215.0 28V8Y@1|root,2ZHBX@2|Bacteria,1RD5G@1224|Proteobacteria,1S39W@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Methylamine dehydrogenase light chain mauA - - - - - - - - - - - Me-amine-dh_L DYD3_k127_5142740_6 1094715.CM001373_gene1482 2.151e-11 64.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1JCN0@118969|Legionellales 118969|Legionellales L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V DYD3_k127_5142740_1 243233.MCA2126 3.298e-94 323.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RXGH@1236|Gammaproteobacteria,1XG2N@135618|Methylococcales 135618|Methylococcales M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4 DYD3_k127_5142740_3 1124991.MU9_1288 4.783e-43 162.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the CinA family ygaD GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA DYD3_k127_5142740_5 697282.Mettu_0053 9.52e-22 102.0 COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SCZX@1236|Gammaproteobacteria,1XFHW@135618|Methylococcales 135618|Methylococcales J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase DYD3_k127_5142740_0 631362.Thi970DRAFT_01214 2.052e-179 568.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,1WW13@135613|Chromatiales 135613|Chromatiales L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA DYD3_k127_5142740_4 1026882.MAMP_02514 3.375e-29 123.0 COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,461G2@72273|Thiotrichales 72273|Thiotrichales S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX DYD3_k127_5142740_2 1232683.ADIMK_1592 8.717e-69 235.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,465GZ@72275|Alteromonadaceae 1236|Gammaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD DYD3_k127_5167899_3 1304275.C41B8_02162 1.55e-28 126.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase phoR GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 DYD3_k127_5167899_1 713586.KB900536_gene1599 7.337e-86 290.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1WVZG@135613|Chromatiales 135613|Chromatiales T phosphate regulon transcriptional regulatory protein PhoB - - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD3_k127_5167899_2 713586.KB900536_gene638 9.092e-48 181.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria,1WX9X@135613|Chromatiales 135613|Chromatiales O PFAM Peptidase M22, glycoprotease - - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 DYD3_k127_5167899_0 572477.Alvin_1128 1.828e-98 336.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales 135613|Chromatiales L Helicase - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2 DYD3_k127_5173165_1 1442599.JAAN01000030_gene2146 4.671e-115 376.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1X4Q2@135614|Xanthomonadales 135614|Xanthomonadales S transporter oliA - - - - - - - - - - - OPT DYD3_k127_5173165_4 1173028.ANKO01000151_gene5291 6.198e-58 218.0 COG0671@1|root,COG2931@1|root,COG0671@2|Bacteria,COG2931@2|Bacteria,1G3V2@1117|Cyanobacteria,1H9MJ@1150|Oscillatoriales 1117|Cyanobacteria Q Hemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - HemolysinCabind,PAP2 DYD3_k127_5173165_0 1278073.MYSTI_06616 5.845e-116 409.0 COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,42PBU@68525|delta/epsilon subdivisions,2WKE2@28221|Deltaproteobacteria,2YTT8@29|Myxococcales 28221|Deltaproteobacteria E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues - - 3.4.17.19 ko:K01299 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M32 DYD3_k127_5173165_3 1121939.L861_01760 5.222e-59 211.0 COG2128@1|root,COG2128@2|Bacteria,1NDTM@1224|Proteobacteria 1224|Proteobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD DYD3_k127_5173165_2 1040982.AXAL01000029_gene4286 1.184e-87 292.0 COG1765@1|root,COG1765@2|Bacteria,1RBJN@1224|Proteobacteria,2VF54@28211|Alphaproteobacteria,43MJG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC DYD3_k127_5173730_1 366394.Smed_5193 3.9e-68 244.0 COG0834@1|root,COG0834@2|Bacteria,1RD36@1224|Proteobacteria,2USIJ@28211|Alphaproteobacteria,4BMC8@82115|Rhizobiaceae 28211|Alphaproteobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 DYD3_k127_5173730_0 339670.Bamb_4345 7.04e-240 752.0 COG0784@1|root,COG1982@1|root,COG0784@2|Bacteria,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,1K2VN@119060|Burkholderiaceae 28216|Betaproteobacteria E PFAM Orn Lys Arg decarboxylase major region adiA - 4.1.1.18,4.1.1.19 ko:K01582,ko:K01584 ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110 M00133 R00462,R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N DYD3_k127_5181318_0 745014.OMB55_00016810 1.527e-193 614.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,1J6AR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - - - - - - - - - - Amidase DYD3_k127_5181318_2 1122137.AQXF01000002_gene562 1.862e-77 266.0 COG3658@1|root,COG3658@2|Bacteria 2|Bacteria C Prokaryotic cytochrome b561 - - - - - - - - - - - - DHC,Ni_hydr_CYTB DYD3_k127_5181318_1 1121405.dsmv_3480 6.496e-171 555.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42SZ7@68525|delta/epsilon subdivisions,2WPA5@28221|Deltaproteobacteria,2MKE2@213118|Desulfobacterales 28221|Deltaproteobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 DYD3_k127_5234800_1 1122603.ATVI01000011_gene2091 1.126e-157 506.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1X43R@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS DYD3_k127_5234800_0 864073.HFRIS_000780 6.398e-161 519.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,472BG@75682|Oxalobacteraceae 28216|Betaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3 DYD3_k127_5234800_3 566466.NOR53_2547 2.045e-52 199.0 28MAS@1|root,2ZAPE@2|Bacteria 2|Bacteria S Protein of unknown function, DUF481 - - - - - - - - - - - - DUF481 DYD3_k127_5234800_2 742159.HMPREF0004_4362 1.039e-54 198.0 2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,2VSQ3@28216|Betaproteobacteria,3T6ZC@506|Alcaligenaceae 28216|Betaproteobacteria S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 DYD3_k127_5242241_1 1379698.RBG1_1C00001G1631 2.225e-43 173.0 COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria 2|Bacteria E Metallopeptidase family M24 pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 DYD3_k127_5242241_0 1249627.D779_3483 1.49e-84 289.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RY2H@1236|Gammaproteobacteria,1WX0H@135613|Chromatiales 135613|Chromatiales GM epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - NAD_binding_10 DYD3_k127_524229_4 1385515.N791_03525 1.979e-15 81.0 COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,1T292@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2,TPR_16,TPR_19,TPR_8 DYD3_k127_524229_5 187272.Mlg_0531 2.568e-08 61.0 2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,1SDJE@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_524229_0 1121374.KB891590_gene1705 3.33e-176 564.0 COG1757@1|root,COG1757@2|Bacteria,1MVDF@1224|Proteobacteria,1RS40@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Na H antiporter nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter DYD3_k127_524229_2 391615.ABSJ01000004_gene630 8.23e-89 304.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1J4EG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S AI-2E family transporter tqsA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944 - ko:K11744 - - - - ko00000 - - - AI-2E_transport DYD3_k127_524229_3 1254432.SCE1572_36020 7.304e-74 253.0 COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,42UKT@68525|delta/epsilon subdivisions,2WQR0@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA DYD3_k127_524229_1 883126.HMPREF9710_03645 3.967e-92 307.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2VHG8@28216|Betaproteobacteria,472KK@75682|Oxalobacteraceae 28216|Betaproteobacteria Q 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - 3.7.1.20 ko:K16165 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R01085 RC00326,RC00446 ko00000,ko00001,ko01000 - - - FAA_hydrolase DYD3_k127_5243863_6 305700.B447_10073 3.518e-33 130.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,2KUCB@206389|Rhodocyclales 206389|Rhodocyclales J Belongs to the class-I aminoacyl-tRNA synthetase family - - - - - - - - - - - - DALR_2,tRNA-synt_1e DYD3_k127_5243863_3 1122603.ATVI01000005_gene2947 3.197e-67 238.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1X4HM@135614|Xanthomonadales 135614|Xanthomonadales E Histidine biosynthesis bifunctional protein HisIE hisI - 3.5.4.19,3.6.1.31 ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH,PRA-PH DYD3_k127_5243863_8 278957.ABEA03000014_gene2546 1.16e-18 94.0 2AD3J@1|root,312RV@2|Bacteria,46YEU@74201|Verrucomicrobia,3K9FE@414999|Opitutae 414999|Opitutae - - - - - - - - - - - - - - - DYD3_k127_5243863_5 748658.KB907313_gene2353 2.734e-58 207.0 2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,1WYF1@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD3_k127_5243863_7 396588.Tgr7_2278 1.979e-23 105.0 COG2980@1|root,COG2980@2|Bacteria,1NGPX@1224|Proteobacteria,1SGKQ@1236|Gammaproteobacteria,1WY80@135613|Chromatiales 135613|Chromatiales M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane lptE - - ko:K03643 - - - - ko00000,ko02000 1.B.42.1 - - LptE DYD3_k127_5243863_0 519989.ECTPHS_03036 0.0 1196.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1WW5E@135613|Chromatiales 135613|Chromatiales J Belongs to the class-I aminoacyl-tRNA synthetase family leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 DYD3_k127_5243863_1 314287.GB2207_00515 2.76e-192 606.0 COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1J4ZH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 DYD3_k127_5243863_2 876044.IMCC3088_221 5.144e-99 335.0 COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria,1J5Y1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25,2.7.7.4 ko:K00860,ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,ATP-sulfurylase,PUA_2 DYD3_k127_5243863_4 1415778.JQMM01000001_gene1077 6.808e-61 214.0 COG1309@1|root,COG1309@2|Bacteria,1RE2I@1224|Proteobacteria,1SH5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N DYD3_k127_5252611_2 1115512.EH105704_03_02460 1.644e-33 132.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,3XN0C@561|Escherichia 1236|Gammaproteobacteria I malonyl CoA-acyl carrier protein transacylase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 DYD3_k127_5252611_1 396588.Tgr7_0230 5.463e-35 141.0 COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,1X1C5@135613|Chromatiales 135613|Chromatiales S Rhomboid family - - - - - - - - - - - - Rhomboid DYD3_k127_5252611_0 765914.ThisiDRAFT_1920 3.276e-57 203.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1WY8U@135613|Chromatiales 135613|Chromatiales U general secretion pathway protein G - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG DYD3_k127_5252611_3 1333856.L686_19380 4.49e-19 94.0 COG2165@1|root,COG2165@2|Bacteria,1N7HZ@1224|Proteobacteria,1SCWD@1236|Gammaproteobacteria,1Z17W@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria U general secretion pathway protein H gspH GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl DYD3_k127_5252611_4 1121937.AUHJ01000003_gene3304 2.006e-17 87.0 COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria 1224|Proteobacteria NU General secretion pathway protein lspI - - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI DYD3_k127_5252611_5 945550.VISI1226_16473 8.354e-05 49.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1XU01@135623|Vibrionales 135623|Vibrionales U general secretion pathway protein epsJ GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ DYD3_k127_5258901_2 1123054.KB907720_gene3286 4.245e-13 78.0 COG0457@1|root,COG0457@2|Bacteria,1NQ31@1224|Proteobacteria,1SJD0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - DYD3_k127_5258901_0 1129374.AJE_09599 9.959e-71 250.0 COG0583@1|root,COG0583@2|Bacteria,1R46P@1224|Proteobacteria,1S061@1236|Gammaproteobacteria 1236|Gammaproteobacteria K LysR family - - - - - - - - - - - - HTH_1,LysR_substrate DYD3_k127_5258901_1 1535422.ND16A_1629 2.17e-68 246.0 COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,1S719@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase DYD3_k127_5270321_0 1535422.ND16A_3225 5.523e-137 450.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,2Q64A@267889|Colwelliaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD3_k127_5270321_1 1129794.C427_2766 3.27e-103 340.0 COG1136@1|root,COG1136@2|Bacteria,1NHCD@1224|Proteobacteria,1RNIX@1236|Gammaproteobacteria,464FN@72275|Alteromonadaceae 1236|Gammaproteobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_5276347_1 392500.Swoo_0696 3.67e-45 175.0 COG2819@1|root,COG2819@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds besA - - ko:K07017 - - - - ko00000 - - - Esterase DYD3_k127_5276347_0 247633.GP2143_14871 2.303e-289 908.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RMPX@1236|Gammaproteobacteria 1236|Gammaproteobacteria S COG2366 Protein related to penicillin acylase pvdQ - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase DYD3_k127_5282345_0 314285.KT71_12215 5.953e-30 134.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - OMP_b-brl_3,Plug,TonB_dep_Rec DYD3_k127_5282345_1 314285.KT71_12245 2.762e-26 114.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088,ko:K03091 - - - - ko00000,ko03021 - - - Ribosomal_S30AE,Sigma70_r2,Sigma70_r4_2 DYD3_k127_5284145_4 416348.Hlac_1771 4.587e-52 188.0 arCOG08955@1|root,arCOG08955@2157|Archaea,2Y5YY@28890|Euryarchaeota 28890|Euryarchaeota - - - - - - - - - - - - - - - DYD3_k127_5284145_3 1121104.AQXH01000001_gene1951 1.278e-64 237.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - - - - - - - - - - Amidohydro_1 DYD3_k127_5284145_2 243090.RB2928 4.387e-65 229.0 COG0454@1|root,COG0456@2|Bacteria,2J0B2@203682|Planctomycetes 203682|Planctomycetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD3_k127_5284145_0 87626.PTD2_03416 1.362e-191 606.0 COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,1RQG2@1236|Gammaproteobacteria,2Q042@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria Q Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate hmgA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0004411,GO:0005488,GO:0005506,GO:0005575,GO:0006082,GO:0006355,GO:0006520,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0019219,GO:0019222,GO:0019439,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051213,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA DYD3_k127_5284145_1 745411.B3C1_07606 1.29e-147 474.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,1J879@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) uptA - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase DYD3_k127_5284145_5 1121015.N789_08290 8.165e-36 140.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1X3M4@135614|Xanthomonadales 135614|Xanthomonadales F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK DYD3_k127_5285126_2 1121434.AULY01000009_gene2267 7.8e-65 239.0 COG3322@1|root,COG4191@1|root,COG3322@2|Bacteria,COG4191@2|Bacteria,1NVWZ@1224|Proteobacteria,42Z33@68525|delta/epsilon subdivisions,2WQTA@28221|Deltaproteobacteria,2MEVN@213115|Desulfovibrionales 28221|Deltaproteobacteria T CHASE4 domain - - - - - - - - - - - - CHASE4,HAMP,HATPase_c DYD3_k127_5285126_3 690850.Desaf_2591 5.858e-26 118.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2M97J@213115|Desulfovibrionales 28221|Deltaproteobacteria T PFAM ATP-binding region ATPase domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg DYD3_k127_5285126_0 1117958.PE143B_0109335 2.027e-107 372.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_7,PAS_8,Response_reg DYD3_k127_5285126_1 402881.Plav_2593 2.164e-72 250.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,1JPPK@119043|Rhodobiaceae 28211|Alphaproteobacteria G PQQ enzyme repeat - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - PQQ,PQQ_2 DYD3_k127_5295544_1 1116472.MGMO_157c00050 8.097e-63 226.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,1S2Y7@1236|Gammaproteobacteria,1XG6U@135618|Methylococcales 135618|Methylococcales O Redoxin - - - - - - - - - - - - AhpC-TSA DYD3_k127_5295544_0 913325.N799_01330 6.886e-101 332.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1X3T3@135614|Xanthomonadales 135614|Xanthomonadales EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase DYD3_k127_5298263_3 1123023.JIAI01000002_gene5656 7.004e-30 124.0 COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria,4E2EY@85010|Pseudonocardiales 201174|Actinobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD3_k127_5298263_0 1149133.ppKF707_1875 0.0 1195.0 COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria,1YDJE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Domain of unknown function (DUF3362) ygiQ - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N DYD3_k127_5298263_2 247634.GPB2148_3155 2.942e-31 132.0 COG3714@1|root,COG3714@2|Bacteria,1QMV7@1224|Proteobacteria,1TH7A@1236|Gammaproteobacteria,1JAKA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S YhhN family - - - - - - - - - - - - YhhN DYD3_k127_5298263_1 713587.THITH_00715 7.085e-86 293.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,1WYQ3@135613|Chromatiales 135613|Chromatiales C Cytochrome c - - - - - - - - - - - - Cytochrom_C DYD3_k127_5298263_4 546266.NEIMUCOT_04632 3.583e-06 49.0 COG3909@1|root,COG3909@2|Bacteria,1MYH4@1224|Proteobacteria,2WFUW@28216|Betaproteobacteria,2KRHX@206351|Neisseriales 206351|Neisseriales C Psort location Periplasmic, score - - - - - - - - - - - - Cytochrom_C_2 DYD3_k127_5313797_1 326297.Sama_0772 4.38e-96 320.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,2Q8HF@267890|Shewanellaceae 1236|Gammaproteobacteria V PFAM ABC transporter related yadG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_5313797_0 1500890.JQNL01000001_gene1551 4.8e-103 344.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1X38I@135614|Xanthomonadales 135614|Xanthomonadales V Transport permease protein yadH - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD3_k127_5313797_2 768671.ThimaDRAFT_1889 2.014e-61 223.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,1S3AX@1236|Gammaproteobacteria,1X2H3@135613|Chromatiales 135613|Chromatiales S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP DYD3_k127_5320699_1 1289387.AUKW01000001_gene4874 2.671e-42 161.0 COG2355@1|root,COG2355@2|Bacteria,2GN82@201174|Actinobacteria 201174|Actinobacteria E Dipeptidase Dpep - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 DYD3_k127_5320699_0 911045.PSE_2334 2.897e-76 267.0 COG0665@1|root,COG0665@2|Bacteria,1R49W@1224|Proteobacteria,2TUH5@28211|Alphaproteobacteria 28211|Alphaproteobacteria E FAD dependent oxidoreductase - - - - - - - - - - - - DAO DYD3_k127_5326081_3 589873.EP13_12335 2.353e-10 61.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,466DN@72275|Alteromonadaceae 1236|Gammaproteobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 DYD3_k127_5326081_2 396588.Tgr7_1074 6.242e-38 147.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1WYVE@135613|Chromatiales 135613|Chromatiales S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd DYD3_k127_5326081_0 396588.Tgr7_1073 1.087e-162 529.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1WX0K@135613|Chromatiales 135613|Chromatiales L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5 DYD3_k127_5326081_1 3055.EDP00620 6.368e-92 312.0 COG1012@1|root,KOG2451@2759|Eukaryota,37KPW@33090|Viridiplantae,34K7P@3041|Chlorophyta 3041|Chlorophyta C Aldehyde dehydrogenase - - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh DYD3_k127_5330009_3 394221.Mmar10_0334 7.267e-09 59.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - TIR_2,TPR_16,TPR_8,Trans_reg_C DYD3_k127_5330009_0 290317.Cpha266_2085 6.36e-114 372.0 COG1432@1|root,COG1432@2|Bacteria,1FECY@1090|Chlorobi 1090|Chlorobi NU OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH DYD3_k127_5330009_2 42565.FP66_13780 3.565e-40 152.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1XKEP@135619|Oceanospirillales 135619|Oceanospirillales M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar DYD3_k127_5330009_1 1250232.JQNJ01000001_gene1661 2.444e-73 259.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD3_k127_533975_4 400668.Mmwyl1_1365 7.555e-48 180.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,1XKMG@135619|Oceanospirillales 135619|Oceanospirillales Q Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT DYD3_k127_533975_5 439292.Bsel_2450 1.093e-16 88.0 COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,26PU6@186821|Sporolactobacillaceae 91061|Bacilli S PFAM DoxX family protein - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX DYD3_k127_533975_1 224914.BMEII0510 8.383e-118 385.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,1J1Y1@118882|Brucellaceae 28211|Alphaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C DYD3_k127_533975_0 1120956.JHZK01000022_gene1565 1.301e-135 441.0 COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2TSPP@28211|Alphaproteobacteria,1JPZM@119043|Rhodobiaceae 28211|Alphaproteobacteria J Initiation factor 2 subunit family mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B DYD3_k127_533975_3 113355.CM001775_gene3061 1.045e-52 197.0 COG0235@1|root,COG0235@2|Bacteria,1G59N@1117|Cyanobacteria 1117|Cyanobacteria G PFAM Class II aldolase - - - - - - - - - - - - Aldolase_II DYD3_k127_533975_6 301.JNHE01000011_gene3676 1.308e-06 57.0 COG0810@1|root,COG0810@2|Bacteria,1NI06@1224|Proteobacteria,1SA5F@1236|Gammaproteobacteria,1YG7Y@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins tonB4 - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD3_k127_533975_2 1279009.ADICEAN_01568 3.751e-71 243.0 COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,47JGG@768503|Cytophagia 976|Bacteroidetes Q dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD3_k127_5381594_1 1198114.AciX9_2007 4.208e-149 484.0 COG2826@1|root,COG2826@2|Bacteria,3Y896@57723|Acidobacteria,2JN59@204432|Acidobacteriia 204432|Acidobacteriia L Helix-turn-helix domain - - - - - - - - - - - - HTH_38,rve DYD3_k127_5381594_0 655815.ZPR_2284 5.344e-205 649.0 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1HXTC@117743|Flavobacteriia 976|Bacteroidetes E gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD3_k127_539371_1 1379698.RBG1_1C00001G1631 7.958e-47 188.0 COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria 2|Bacteria E Metallopeptidase family M24 pepP GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 DYD3_k127_539371_0 1120948.KB903243_gene2613 1.057e-157 509.0 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZWD@85010|Pseudonocardiales 201174|Actinobacteria IQ AMP-binding enzyme - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C DYD3_k127_5407924_2 1123242.JH636434_gene3744 2.534e-70 247.0 COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes 203682|Planctomycetes Q PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_3 DYD3_k127_5407924_0 1120953.AUBH01000008_gene260 7.711e-148 484.0 COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQGU@1236|Gammaproteobacteria,465Y7@72275|Alteromonadaceae 1236|Gammaproteobacteria E Zn-dependent dipeptidase, microsomal dipeptidase acdP - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 DYD3_k127_5407924_1 215803.DB30_4063 1.577e-132 430.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales 28221|Deltaproteobacteria Q Amidohydrolase family - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 DYD3_k127_5430039_2 316274.Haur_3390 2.97e-49 182.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2G8T7@200795|Chloroflexi,3780G@32061|Chloroflexia 200795|Chloroflexi T histidine kinase HAMP region domain protein - - - - - - - - - - - - HATPase_c,HisKA,PAS_4 DYD3_k127_5430039_1 1128421.JAGA01000001_gene2454 5.049e-68 240.0 COG0745@1|root,COG0745@2|Bacteria,2NQZN@2323|unclassified Bacteria 2|Bacteria K Two component transcriptional regulator, winged helix family - - - - - - - - - - - - Response_reg,Trans_reg_C DYD3_k127_5430039_0 1232683.ADIMK_0084 8.678e-168 546.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD3_k127_5430039_3 68570.DC74_7665 4.378e-09 57.0 COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria 201174|Actinobacteria OT Pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,cNMP_binding DYD3_k127_5444162_4 1122609.AUGT01000012_gene4354 3.847e-35 141.0 COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4DNTB@85009|Propionibacteriales 201174|Actinobacteria E Indole-3-glycerol phosphate synthase trpC GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS DYD3_k127_5444162_5 1121430.JMLG01000010_gene187 9.15e-30 128.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,2623G@186807|Peptococcaceae 186801|Clostridia E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI DYD3_k127_5444162_0 40571.JOEA01000008_gene2768 2.943e-132 434.0 COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4DZ8F@85010|Pseudonocardiales 201174|Actinobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - IGPS,PALP DYD3_k127_5444162_2 1128421.JAGA01000002_gene1341 1.077e-57 211.0 COG0159@1|root,COG0159@2|Bacteria,2NP9W@2323|unclassified Bacteria 2|Bacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA DYD3_k127_5444162_6 472759.Nhal_0470 1.158e-21 98.0 2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,1SD5T@1236|Gammaproteobacteria,1X269@135613|Chromatiales 135613|Chromatiales S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 DYD3_k127_5444162_1 768704.Desmer_1011 4.514e-111 385.0 COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae 186801|Clostridia T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_9 DYD3_k127_5444162_3 861299.J421_4375 1.046e-43 167.0 COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_5444162_7 1216007.AOPM01000071_gene1572 7.15e-06 56.0 2CKCT@1|root,32SC5@2|Bacteria,1N1BJ@1224|Proteobacteria,1S8RE@1236|Gammaproteobacteria,2Q2TX@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_5445394_1 1353537.TP2_15430 5.393e-171 547.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2XP76@285107|Thioclava 28211|Alphaproteobacteria C Aldehyde dehydrogenase - - 1.2.1.99 ko:K09472 ko00330,ko01100,map00330,map01100 M00136 R07417,R07418 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD3_k127_5445394_0 1122135.KB893134_gene3134 2.281e-188 610.0 COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1042 Acyl-CoA synthetase (NDP forming) - - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig DYD3_k127_5445394_3 247639.MGP2080_02515 1.133e-149 490.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - DUF1989,GCV_T,GCV_T_C DYD3_k127_5445394_2 1122135.KB893134_gene3132 3.207e-159 517.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Phytoene dehydrogenase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 DYD3_k127_5445394_4 1449065.JMLL01000014_gene3187 1.355e-76 258.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,43J3W@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q COG1233 Phytoene dehydrogenase and related - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 DYD3_k127_5447385_0 94624.Bpet3623 8.928e-173 546.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,3T31E@506|Alcaligenaceae 28216|Betaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N DYD3_k127_5447385_1 187272.Mlg_2842 1.807e-172 549.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1WX6Z@135613|Chromatiales 135613|Chromatiales F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK DYD3_k127_5447385_2 1415779.JOMH01000001_gene274 1.016e-58 208.0 COG3211@1|root,COG3211@2|Bacteria,1QY0R@1224|Proteobacteria,1S13A@1236|Gammaproteobacteria,1X5KR@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839,TAT_signal DYD3_k127_5454343_1 1123368.AUIS01000023_gene933 1.021e-134 445.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales 225057|Acidithiobacillales T Diguanylate cyclase - - - - - - - - - - - - CZB,EAL,GGDEF,PAS,PAS_4 DYD3_k127_5454343_0 1266925.JHVX01000003_gene387 1.206e-149 477.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,371QC@32003|Nitrosomonadales 28216|Betaproteobacteria C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA DYD3_k127_5457946_1 1122194.AUHU01000005_gene985 3.674e-130 457.0 COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1R5Q7@1224|Proteobacteria,1RPH2@1236|Gammaproteobacteria,465FR@72275|Alteromonadaceae 1236|Gammaproteobacteria E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,Transglut_core DYD3_k127_5457946_3 247633.GP2143_14461 7.2e-74 251.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Aerobic-type carbon monoxide dehydrogenase small subunit CoxS - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 DYD3_k127_5457946_0 247633.GP2143_14456 0.0 1133.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - - - - - - - - - - - Ald_Xan_dh_C2 DYD3_k127_5457946_2 349521.HCH_04191 3.49e-118 385.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,1RNGM@1236|Gammaproteobacteria,1XHQ1@135619|Oceanospirillales 135619|Oceanospirillales S NAD(P)-dependent - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N DYD3_k127_5464754_1 1215092.PA6_005_00170 2.008e-73 255.0 COG2259@1|root,COG2259@2|Bacteria,1RBZP@1224|Proteobacteria,1S28E@1236|Gammaproteobacteria,1YDSB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S DoxX - - - - - - - - - - - - DoxX DYD3_k127_5464754_0 1382359.JIAL01000001_gene444 2.59e-81 282.0 COG2021@1|root,COG2021@2|Bacteria,3Y4JM@57723|Acidobacteria,2JJBE@204432|Acidobacteriia 204432|Acidobacteriia E alpha/beta hydrolase fold - - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 DYD3_k127_5465335_3 382464.ABSI01000012_gene2200 9.264e-22 111.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C DYD3_k127_5465335_2 243231.GSU0250 4.823e-24 107.0 2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,42W05@68525|delta/epsilon subdivisions,2WS7Z@28221|Deltaproteobacteria,43VK6@69541|Desulfuromonadales 28221|Deltaproteobacteria S Protein of unknown function (DUF2721) - - - - - - - - - - - - DUF2721 DYD3_k127_5465335_0 1472716.KBK24_0111595 2.197e-53 193.0 COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,1K3AS@119060|Burkholderiaceae 28216|Betaproteobacteria O PFAM OsmC family protein osmC - - ko:K04063 - - - - ko00000 - - - OsmC DYD3_k127_5465335_1 1116369.KB890024_gene1976 3.454e-25 106.0 29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,2UUDN@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_5482180_1 1535422.ND16A_3773 1.274e-92 316.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008194,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 iSFV_1184.SFV_3438 Glyco_transf_5,Glycos_transf_1 DYD3_k127_5482180_0 2340.JV46_03910 5.371e-201 632.0 COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1J9TH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase DYD3_k127_5507913_1 1117958.PE143B_0122980 1.766e-54 196.0 COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria 1236|Gammaproteobacteria P belongs to the Fur family zur - - ko:K09823 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - FUR DYD3_k127_5507913_0 596152.DesU5LDRAFT_0157 1.466e-236 746.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2M7XR@213115|Desulfovibrionales 28221|Deltaproteobacteria J PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C DYD3_k127_5507913_2 518766.Rmar_1448 4.14e-49 185.0 COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1FIS0@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans DYD3_k127_5507913_3 247633.GP2143_07954 2.035e-29 119.0 COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,1SD41@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 DYD3_k127_5509384_6 1384056.N787_01010 1.598e-91 308.0 COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,1RS51@1236|Gammaproteobacteria,1X58W@135614|Xanthomonadales 135614|Xanthomonadales S Glutamine - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 DYD3_k127_5509384_2 1121004.ATVC01000019_gene1852 1.507e-162 523.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2VJHJ@28216|Betaproteobacteria,2KQB5@206351|Neisseriales 206351|Neisseriales E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C DYD3_k127_5509384_1 1323663.AROI01000033_gene4055 1.781e-197 624.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family spuC - 2.6.1.113 ko:K12256 ko00330,ko01100,map00330,map01100 - R08714 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - iJN746.PP_5182 Aminotran_3 DYD3_k127_5509384_4 448385.sce9154 1.854e-136 440.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MKW@68525|delta/epsilon subdivisions,2WKFI@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Belongs to the arginase family - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD3_k127_5509384_7 588932.JHOF01000026_gene394 8.219e-66 230.0 COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,2TU8R@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator MA20_09770 - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 DYD3_k127_5509384_3 305900.GV64_09645 1.533e-154 498.0 COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1XHUF@135619|Oceanospirillales 135619|Oceanospirillales E Oxidoreductase - - - - - - - - - - - - DAO DYD3_k127_5509384_0 935261.JAGL01000002_gene1349 5.554e-199 629.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,43GQV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.18 ko:K00822 ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100 - R00907,R04187 RC00008,RC00062,RC00160 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 DYD3_k127_5509384_5 713586.KB900536_gene1315 1.058e-131 429.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1WZY2@135613|Chromatiales 135613|Chromatiales C Aldehyde dehydrogenase family - - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD3_k127_55225_1 566466.NOR53_3522 3.041e-38 166.0 COG0457@1|root,COG0457@2|Bacteria,1MYQU@1224|Proteobacteria,1RWMR@1236|Gammaproteobacteria,1JABK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Tetratricopeptide repeat - - - - - - - - - - - - TPR_12,TPR_7 DYD3_k127_55225_0 857087.Metme_2051 3.684e-207 676.0 COG0785@1|root,COG3209@1|root,COG0785@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis mauF - 2.7.11.1 ko:K03466,ko:K06196,ko:K12132 - - - - ko00000,ko01000,ko01001,ko02000,ko03036 3.A.12,5.A.1.2 - - AAA_16,Trans_reg_C DYD3_k127_5526848_3 118166.JH976537_gene2197 1.002e-29 125.0 2BH5I@1|root,32B6M@2|Bacteria,1GDPJ@1117|Cyanobacteria,1HFC9@1150|Oscillatoriales 1117|Cyanobacteria S Nuclease-related domain - - - - - - - - - - - - NERD DYD3_k127_5526848_0 1123508.JH636439_gene1340 9.036e-274 860.0 COG1505@1|root,COG1505@2|Bacteria,2IXRJ@203682|Planctomycetes 203682|Planctomycetes E Prolyl oligopeptidase - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N DYD3_k127_5526848_1 1121013.P873_14190 1.467e-97 327.0 COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1X5FC@135614|Xanthomonadales 135614|Xanthomonadales S Extradiol ring-cleavage dioxygenase - - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB DYD3_k127_5526848_2 1278307.KB906968_gene2090 3.333e-31 123.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,2QJ6G@267894|Psychromonadaceae 1236|Gammaproteobacteria K Cold shock protein domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD DYD3_k127_5533433_5 261292.Nit79A3_1725 3.082e-30 121.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,373BM@32003|Nitrosomonadales 28216|Betaproteobacteria S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection ybaB - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd DYD3_k127_5533433_0 1384056.N787_08025 2.411e-77 263.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1X30Z@135614|Xanthomonadales 135614|Xanthomonadales L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 DYD3_k127_5533433_4 713586.KB900536_gene189 1.033e-44 168.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales 135613|Chromatiales FG PFAM Histidine triad (HIT) protein - - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT DYD3_k127_5533433_3 519989.ECTPHS_10296 1.537e-56 213.0 COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1WW4C@135613|Chromatiales 135613|Chromatiales S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase DYD3_k127_5533433_1 1245471.PCA10_51890 4.02e-72 248.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1YE7U@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria A 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T DYD3_k127_5533433_2 870187.Thini_0776 2.081e-57 212.0 COG2230@1|root,COG2230@2|Bacteria,1QVX6@1224|Proteobacteria,1T2MM@1236|Gammaproteobacteria,4628Q@72273|Thiotrichales 72273|Thiotrichales M Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 DYD3_k127_5533722_2 1123377.AUIV01000033_gene53 6.013e-30 121.0 COG3952@1|root,COG3952@2|Bacteria,1NFUX@1224|Proteobacteria,1SJ0F@1236|Gammaproteobacteria,1X716@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - LAB_N DYD3_k127_5533722_0 1211114.ALIP01000122_gene2121 2.592e-134 448.0 COG1807@1|root,COG1807@2|Bacteria,1MXH5@1224|Proteobacteria,1RSQE@1236|Gammaproteobacteria,1X415@135614|Xanthomonadales 135614|Xanthomonadales M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 DYD3_k127_5533722_1 1384056.N787_04805 7.222e-129 422.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RNVA@1236|Gammaproteobacteria,1X6C3@135614|Xanthomonadales 135614|Xanthomonadales S Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5,TPR_16,TPR_19 DYD3_k127_5541648_4 1121921.KB898708_gene1457 1.362e-50 185.0 COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria,2PMMF@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria FJ tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE DYD3_k127_5541648_3 991905.SL003B_2672 6.681e-136 445.0 COG0742@1|root,COG0742@2|Bacteria,1MW6A@1224|Proteobacteria,2TQNI@28211|Alphaproteobacteria 28211|Alphaproteobacteria L ribosomal rna small subunit methyltransferase MA20_07810 - - - - - - - - - - - - DYD3_k127_5541648_1 565045.NOR51B_1530 4.595e-166 530.0 COG0620@1|root,COG0620@2|Bacteria,1QJ82@1224|Proteobacteria,1TH64@1236|Gammaproteobacteria,1J9IH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E E COG0620 Methionine synthase II (cobalamin-independent) - - - - - - - - - - - - Meth_synt_2 DYD3_k127_5541648_2 566466.NOR53_3663 5.814e-159 507.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_2698 Meth_synt_2 DYD3_k127_5541648_0 566466.NOR53_3686 2.786e-208 652.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1JA8Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H COG1541 Coenzyme F390 synthetase - - - - - - - - - - - - AMP-binding,AMP-binding_C_2 DYD3_k127_5559708_2 1211114.ALIP01000115_gene1475 3.232e-82 276.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales 135614|Xanthomonadales IQ Activates fatty acids by binding to coenzyme A rpfB - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD3_k127_5559708_0 1517416.IDAT_04440 1.626e-154 497.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,2QF55@267893|Idiomarinaceae 1236|Gammaproteobacteria H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3734,iSBO_1134.SBO_4018 URO-D DYD3_k127_5559708_1 243233.MCA1094 7.33e-97 322.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XEBB@135618|Methylococcales 135618|Methylococcales F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase DYD3_k127_5559708_3 713586.KB900536_gene1839 1.161e-42 161.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1X0VD@135613|Chromatiales 135613|Chromatiales F Belongs to the dGTPase family. Type 2 subfamily - - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc DYD3_k127_5576270_1 1469948.JPNB01000001_gene2027 1.147e-09 59.0 COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,36DXS@31979|Clostridiaceae 186801|Clostridia I Alpha beta - - - - - - - - - - - - Hydrolase_4 DYD3_k127_5576270_0 1122137.AQXF01000001_gene2679 4.736e-210 685.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,2TRCG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_5587938_1 1304275.C41B8_00905 8.111e-123 399.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Glutamate synthase gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 GATase_2,GXGXG,Glu_syn_central,Glu_synthase DYD3_k127_5587938_0 713586.KB900536_gene1827 1.177e-223 701.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales 135613|Chromatiales C Pyridine nucleotide-disulphide oxidoreductase - - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 DYD3_k127_5607707_3 247639.MGP2080_02481 7.173e-25 104.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,1JBXZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - ko:K00479 - - - - ko00000 - - - Rieske,Ring_hydroxyl_A DYD3_k127_5607707_4 398580.Dshi_3273 5.005e-09 68.0 COG1560@1|root,COG1560@2|Bacteria 2|Bacteria M Kdo2-lipid A biosynthetic process - - 2.3.1.241,2.3.1.265 ko:K02517,ko:K20543,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 1.B.55.3 - - Lip_A_acyltrans DYD3_k127_5607707_0 84531.JMTZ01000061_gene1968 7.386e-84 308.0 COG2091@1|root,COG2091@2|Bacteria,1R6N3@1224|Proteobacteria,1RNGX@1236|Gammaproteobacteria,1X983@135614|Xanthomonadales 135614|Xanthomonadales H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - - DYD3_k127_5607707_1 349521.HCH_05059 5.532e-77 265.0 COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,1S3RR@1236|Gammaproteobacteria,1XJTS@135619|Oceanospirillales 135619|Oceanospirillales S Threonyl and Alanyl tRNA synthetase second additional domain - - - ko:K07050 - - - - ko00000,ko01000,ko03016 - - - tRNA-synt_2c,tRNA_SAD DYD3_k127_5607707_2 1041146.ATZB01000095_gene2807 1.417e-57 222.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,4B9YM@82115|Rhizobiaceae 28211|Alphaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase DYD3_k127_5608602_2 926550.CLDAP_19040 1.238e-52 194.0 COG1414@1|root,COG1414@2|Bacteria,2G71X@200795|Chloroflexi 200795|Chloroflexi K helix_turn_helix isocitrate lyase regulation - - - - - - - - - - - - HTH_IclR,IclR DYD3_k127_5608602_0 1122135.KB893168_gene1824 8.697e-129 428.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2TTPD@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamine synthetase glnA GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C DYD3_k127_5608602_1 1282876.BAOK01000001_gene3466 2.107e-126 428.0 COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,2U5M0@28211|Alphaproteobacteria,4BT1G@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_5608602_3 1173027.Mic7113_2530 1.92e-22 105.0 COG0534@1|root,COG0534@2|Bacteria,1G1F8@1117|Cyanobacteria,1H8MX@1150|Oscillatoriales 1117|Cyanobacteria V efflux protein, MATE family - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD3_k127_561646_5 1236542.BALM01000014_gene1194 3.519e-14 74.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QA13@267890|Shewanellaceae 1236|Gammaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family acrF - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran DYD3_k127_561646_1 713586.KB900536_gene1447 2.355e-74 264.0 COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WWA8@135613|Chromatiales 135613|Chromatiales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 DYD3_k127_561646_0 1120953.AUBH01000006_gene2671 6.203e-113 373.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,4645T@72275|Alteromonadaceae 1236|Gammaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - iYL1228.KPN_03597,ic_1306.c3945 polyprenyl_synt DYD3_k127_561646_3 314278.NB231_04027 7.062e-30 126.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,1WYVV@135613|Chromatiales 135613|Chromatiales J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p DYD3_k127_561646_2 713586.KB900536_gene1913 8.196e-36 137.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1WYVD@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 DYD3_k127_561646_4 1120931.KB893930_gene1657 6.379e-24 103.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1Y7HZ@135625|Pasteurellales 135625|Pasteurellales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 DYD3_k127_5623476_0 1227453.C444_09560 6.598e-11 75.0 COG0642@1|root,arCOG02327@2157|Archaea,2XTH8@28890|Euryarchaeota,23S6Q@183963|Halobacteria 183963|Halobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,HisKA_7TM,PAS_4,PAS_8 DYD3_k127_5623476_1 1121028.ARQE01000008_gene2382 0.0001347 54.0 COG5001@1|root,COG5001@2|Bacteria 2|Bacteria T cyclic-guanylate-specific phosphodiesterase activity - - - - - - - - - - - - BLUF,GGDEF DYD3_k127_5632592_0 1280949.HAD_10845 1.108e-144 464.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2TUDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD3_k127_5632592_1 59538.XP_005977964.1 3.878e-109 371.0 COG1012@1|root,KOG2450@2759|Eukaryota,38CDB@33154|Opisthokonta,3BCJG@33208|Metazoa,3CU6J@33213|Bilateria 33208|Metazoa C aldehyde dehydrogenase (NAD) activity - - - - - - - - - - - - Aldedh DYD3_k127_5632930_1 279238.Saro_0800 7.979e-42 160.0 COG2271@1|root,COG2271@2|Bacteria,1P3P1@1224|Proteobacteria,2TVM7@28211|Alphaproteobacteria,2K00U@204457|Sphingomonadales 204457|Sphingomonadales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_5632930_0 1163409.UUA_06189 9.59e-69 240.0 COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1X5ID@135614|Xanthomonadales 135614|Xanthomonadales L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp DYD3_k127_5632930_3 1380394.JADL01000010_gene4285 8.711e-12 66.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JQY7@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD3_k127_5637048_0 1510531.JQJJ01000010_gene2360 3.141e-268 838.0 COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,3JX2W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1,Thioredoxin_4 DYD3_k127_5637048_1 314275.MADE_1001145 7.646e-215 678.0 COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,463ZX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family sglT - - ko:K03307 - - - - ko00000 2.A.21 - - SSF DYD3_k127_5637048_3 1229172.JQFA01000002_gene3304 6.866e-103 341.0 COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,1H7AV@1150|Oscillatoriales 1117|Cyanobacteria S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin DYD3_k127_5637048_2 1198452.Jab_1c25180 2.301e-160 524.0 COG0492@1|root,COG0492@2|Bacteria,1MVX2@1224|Proteobacteria,2VM3V@28216|Betaproteobacteria 28216|Betaproteobacteria C FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,cNMP_binding DYD3_k127_5642384_0 450851.PHZ_c2202 6.589e-54 201.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - - - - - - - - - - Lactamase_B DYD3_k127_5642384_1 565045.NOR51B_1560 1.518e-42 159.0 2DN6U@1|root,32VVA@2|Bacteria,1N6AG@1224|Proteobacteria,1SQ0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Cysteine rich repeat - - - - - - - - - - - - Cys_rich_FGFR DYD3_k127_5642384_2 95619.PM1_0224040 1.436e-05 49.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria 1224|Proteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K14392 - - - - ko00000,ko02000 2.A.21.1 - - SSF DYD3_k127_565256_2 663610.JQKO01000008_gene70 2.091e-09 60.0 COG0265@1|root,COG0265@2|Bacteria,1N58P@1224|Proteobacteria,2TTTZ@28211|Alphaproteobacteria,3NA58@45404|Beijerinckiaceae 28211|Alphaproteobacteria O Trypsin MA20_17565 - - - - - - - - - - - PDZ_2,Trypsin_2 DYD3_k127_565256_0 713586.KB900536_gene2827 1.702e-35 142.0 COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin DYD3_k127_566059_0 566466.NOR53_1180 1.485e-189 599.0 COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1J8ZH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - - - - - - - - - - M20_dimer,Peptidase_M20 DYD3_k127_566059_1 153948.NAL212_1251 1.935e-20 93.0 COG2119@1|root,COG2119@2|Bacteria,1NDE6@1224|Proteobacteria 1224|Proteobacteria S family UPF0016 - - - - - - - - - - - - UPF0016 DYD3_k127_5662555_4 1137271.AZUM01000001_gene807 4.276e-09 61.0 COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4E3IH@85010|Pseudonocardiales 201174|Actinobacteria I Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 DYD3_k127_5662555_3 644282.Deba_0147 1.026e-49 191.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WPU4@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Pyridoxal-phosphate dependent enzyme - - 4.4.1.15 ko:K05396 ko00270,map00270 - R01874 RC00382 ko00000,ko00001,ko01000 - - - PALP DYD3_k127_5662555_2 1215092.PA6_046_00230 1.411e-50 199.0 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria,1YH70@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C DYD3_k127_5662555_1 870187.Thini_2828 7.3e-57 203.0 COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,462J6@72273|Thiotrichales 72273|Thiotrichales S Putative member of DMT superfamily (DUF486) - - - - - - - - - - - - DMT_6 DYD3_k127_5662555_0 1121033.AUCF01000021_gene2886 1.5e-321 1006.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQPR@204441|Rhodospirillales 204441|Rhodospirillales EQ Hydantoinase/oxoprolinase N-terminal region - - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B DYD3_k127_5683101_0 1238182.C882_1658 9.419e-245 777.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JQY7@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD3_k127_5683101_2 627192.SLG_28740 4.919e-118 396.0 COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2U1SE@28211|Alphaproteobacteria,2K2V3@204457|Sphingomonadales 204457|Sphingomonadales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_5683101_3 1056816.JAFQ01000004_gene4529 2.394e-101 349.0 COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria,4FYN9@85025|Nocardiaceae 201174|Actinobacteria CH FAD binding domain - - 1.14.13.127 ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06786,R06787 RC00236 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,FAD_binding_3 DYD3_k127_5683101_1 627192.SLG_38050 2.044e-142 483.0 COG1629@1|root,COG4771@2|Bacteria,1NU2Y@1224|Proteobacteria,2UPZC@28211|Alphaproteobacteria,2K91N@204457|Sphingomonadales 204457|Sphingomonadales P Protein involved in receptor activity and transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_5743118_2 1415779.JOMH01000001_gene2699 7.964e-40 153.0 COG2050@1|root,COG2050@2|Bacteria,1RDNY@1224|Proteobacteria,1SC2Y@1236|Gammaproteobacteria,1XD0W@135614|Xanthomonadales 135614|Xanthomonadales Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 DYD3_k127_5743118_4 1191460.F959_02531 9.26e-05 49.0 2EGFZ@1|root,33A7Y@2|Bacteria,1NI1P@1224|Proteobacteria,1SVCS@1236|Gammaproteobacteria,3NPF6@468|Moraxellaceae 1236|Gammaproteobacteria S Ribosomal protein L7/L12 C-terminal domain - - - - - - - - - - - - Ribosomal_L12 DYD3_k127_5743118_3 314345.SPV1_08761 9.795e-18 89.0 2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF4389) - - - - - - - - - - - - DUF4389 DYD3_k127_5743118_0 1300345.LF41_1697 1.508e-151 494.0 COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,1X2ZT@135614|Xanthomonadales 135614|Xanthomonadales E Acetylornithine deacetylase Succinyl-diaminopimelate - - - - - - - - - - - - M20_dimer,Peptidase_M20,Peptidase_M28 DYD3_k127_5743118_1 1123073.KB899242_gene1451 2.138e-113 371.0 COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1X5RA@135614|Xanthomonadales 135614|Xanthomonadales Q Amidohydrolase family - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 DYD3_k127_5755104_2 1122612.AUBA01000002_gene1696 4.201e-31 130.0 2ED7G@1|root,31A10@2|Bacteria,1NV3Q@1224|Proteobacteria,2URPA@28211|Alphaproteobacteria,2KA1R@204457|Sphingomonadales 204457|Sphingomonadales S SnoaL-like domain - - - - - - - - - - - - SnoaL_4 DYD3_k127_5755104_1 702113.PP1Y_AT11594 2.236e-127 414.0 COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,2TSEM@28211|Alphaproteobacteria,2K9JF@204457|Sphingomonadales 204457|Sphingomonadales S KR domain - - - - - - - - - - - - adh_short DYD3_k127_5755104_0 935840.JAEQ01000018_gene2029 3.528e-219 690.0 COG0404@1|root,COG0404@2|Bacteria,1MWZS@1224|Proteobacteria,2TSVD@28211|Alphaproteobacteria,43JE4@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Aminomethyltransferase folate-binding domain - - - ko:K15064 ko00627,ko01120,map00627,map01120 - R09270 RC00113,RC00392 ko00000,ko00001,ko01000 - - - GCV_T,GCV_T_C DYD3_k127_5760784_3 1415779.JOMH01000001_gene1318 9.803e-50 183.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1X4RY@135614|Xanthomonadales 135614|Xanthomonadales NU secretion system protein xcsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N DYD3_k127_5760784_1 713586.KB900536_gene2363 2.247e-211 668.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales 135613|Chromatiales NU PFAM Type II secretion system protein E - - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N DYD3_k127_5760784_2 187272.Mlg_2392 1.117e-130 428.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WXA3@135613|Chromatiales 135613|Chromatiales U General secretion pathway protein F - - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF DYD3_k127_5760784_0 187272.Mlg_1175 0.0 1042.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1WW62@135613|Chromatiales 135613|Chromatiales L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 - 2.7.7.7 ko:K14162 - - - - ko00000,ko01000,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon DYD3_k127_5764299_0 1500893.JQNB01000001_gene1516 1.969e-128 417.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1X44J@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus DYD3_k127_5764299_1 1049564.TevJSym_ab01230 7.513e-82 287.0 COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H protein methyltransferase activity - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 DYD3_k127_5764679_2 1123377.AUIV01000015_gene276 1.592e-47 183.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1X68Z@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf DYD3_k127_5764679_3 869210.Marky_0418 1.654e-43 170.0 COG1597@1|root,COG1597@2|Bacteria,1WI0N@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I PFAM Diacylglycerol kinase, catalytic bmrU - - - - - - - - - - - DAGK_cat DYD3_k127_5764679_1 690850.Desaf_2287 4.366e-65 234.0 COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,42QVG@68525|delta/epsilon subdivisions,2WNKA@28221|Deltaproteobacteria,2M9AG@213115|Desulfovibrionales 28221|Deltaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA DYD3_k127_5764679_4 1144275.COCOR_01490 5.621e-41 162.0 COG5658@1|root,COG5658@2|Bacteria,1NBU4@1224|Proteobacteria 1224|Proteobacteria S integral membrane protein - - - - - - - - - - - - DUF1648,SdpI DYD3_k127_5764679_0 105559.Nwat_1620 4.018e-179 575.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1WWJW@135613|Chromatiales 135613|Chromatiales S protease with the C-terminal PDZ domain - - - - - - - - - - - - PDZ_2,Peptidase_M61 DYD3_k127_5781078_1 1415778.JQMM01000001_gene1828 2.445e-56 211.0 COG2188@1|root,COG2188@2|Bacteria,1QVF7@1224|Proteobacteria,1S5D3@1236|Gammaproteobacteria,1J8FY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - - - - - - - - - - Porin_5 DYD3_k127_5781078_0 1033802.SSPSH_002133 6.964e-80 273.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU DYD3_k127_5781078_2 1163409.UUA_07013 1.768e-35 141.0 COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,1S6WD@1236|Gammaproteobacteria,1X6GW@135614|Xanthomonadales 135614|Xanthomonadales O Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein dsbB - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB DYD3_k127_5789645_0 1121937.AUHJ01000012_gene2722 3.264e-185 591.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,46475@72275|Alteromonadaceae 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases bbsG - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD3_k127_5789645_1 1121940.AUDZ01000007_gene2334 3.923e-42 160.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XIU0@135619|Oceanospirillales 135619|Oceanospirillales C FAD linked oxidase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 DYD3_k127_5792894_4 1089544.KB912942_gene2635 5.527e-05 51.0 COG1917@1|root,COG1917@2|Bacteria,2IQ74@201174|Actinobacteria,4ECDH@85010|Pseudonocardiales 201174|Actinobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - DYD3_k127_5792894_0 1128912.GMES_3981 1.401e-31 128.0 2F2K4@1|root,33VGY@2|Bacteria,1NV1B@1224|Proteobacteria,1SNNT@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_5792894_1 1301098.PKB_1467 5.757e-13 76.0 COG5608@1|root,COG5608@2|Bacteria 2|Bacteria S Late embryogenesis abundant protein - - - - - - - - - - - - LEA_2 DYD3_k127_5792894_3 1348657.M622_05745 1.85e-09 63.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2VSHT@28216|Betaproteobacteria,2KYXG@206389|Rhodocyclales 206389|Rhodocyclales S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 DYD3_k127_5792990_1 390235.PputW619_3803 1.484e-130 438.0 COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1YV2D@136845|Pseudomonas putida group 1236|Gammaproteobacteria M Surface antigen variable number plpD - - ko:K07001 - - - - ko00000 - - - Bac_surface_Ag,POTRA,Patatin DYD3_k127_5792990_3 472759.Nhal_2970 7.51e-12 70.0 2EFZ6@1|root,339RC@2|Bacteria,1P76P@1224|Proteobacteria,1SIDJ@1236|Gammaproteobacteria,1X1PM@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD3_k127_5792990_2 215803.DB30_6069 1.378e-72 280.0 COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YXT4@29|Myxococcales 28221|Deltaproteobacteria S AAA-like domain - - - - - - - - - - - - AAA_35,Pkinase,WD40 DYD3_k127_5792990_0 1123073.KB899241_gene3008 4.247e-220 699.0 COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1X3Z7@135614|Xanthomonadales 135614|Xanthomonadales I Acyltransferase aas - - - - - - - - - - - Acyltransferase,MFS_1 DYD3_k127_5800073_2 1123228.AUIH01000087_gene415 2.743e-13 79.0 COG0737@1|root,COG0823@1|root,COG0737@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - - ko:K03641,ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 2.C.1.2,3.A.1.1.28 - - Cytochrome_C554,PD40,SBP_bac_8 DYD3_k127_5800073_1 234267.Acid_7677 3.473e-41 162.0 COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria 57723|Acidobacteria K ECF sigma factor - - - - - - - - - - - - Sigma70_ECF DYD3_k127_5800073_0 1089550.ATTH01000001_gene1831 3.537e-160 539.0 COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - NERD,Pkinase,TPR_12,TPR_8 DYD3_k127_5805535_2 28229.ND2E_1735 2.465e-34 148.0 COG1566@1|root,COG1566@2|Bacteria,1RJ3I@1224|Proteobacteria,1S7BS@1236|Gammaproteobacteria,2Q65P@267889|Colwelliaceae 1236|Gammaproteobacteria V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 DYD3_k127_5805535_1 1479237.JMLY01000001_gene3299 1.123e-35 147.0 2CD0I@1|root,32RWS@2|Bacteria,1N0MC@1224|Proteobacteria,1SABW@1236|Gammaproteobacteria,46827@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4399) - - - - - - - - - - - - DUF4399 DYD3_k127_5805535_0 1304275.C41B8_11553 6.625e-130 424.0 COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria 1236|Gammaproteobacteria I synthase - - 2.3.3.10 ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000,ko01008 - - - HMG_CoA_synt_C,HMG_CoA_synt_N DYD3_k127_5805973_2 290397.Adeh_3359 6.28e-11 68.0 2AFPW@1|root,315RN@2|Bacteria,1N1K1@1224|Proteobacteria,42WWK@68525|delta/epsilon subdivisions,2WSXP@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_5805973_0 1500257.JQNM01000001_gene3364 2.545e-81 286.0 COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,2TQUT@28211|Alphaproteobacteria,4BD1H@82115|Rhizobiaceae 28211|Alphaproteobacteria E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 DYD3_k127_5805973_1 566466.NOR53_3413 6.566e-20 92.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 DYD3_k127_5807913_0 880071.Fleli_3541 1.16e-146 471.0 COG1086@1|root,COG1086@2|Bacteria,4NGN2@976|Bacteroidetes,47MCI@768503|Cytophagia 976|Bacteroidetes M Polysaccharide biosynthesis protein pseB - 4.2.1.115 ko:K15894 ko00520,map00520 - R09697 RC02609 ko00000,ko00001,ko01000 - - - Polysacc_synt_2 DYD3_k127_5807913_1 63737.Npun_R0689 8.074e-97 321.0 COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria,1HKXG@1161|Nostocales 1117|Cyanobacteria E DegT DnrJ EryC1 StrS aminotransferase - - - - - - - - - - - - DegT_DnrJ_EryC1 DYD3_k127_5813113_2 1236542.BALM01000032_gene2175 3.017e-30 124.0 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,2QD6D@267890|Shewanellaceae 1236|Gammaproteobacteria S NnrU protein nnrU - - - - - - - - - - - NnrU DYD3_k127_5813113_0 1121033.AUCF01000015_gene1435 1.071e-94 320.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSR9@28211|Alphaproteobacteria,2JQUK@204441|Rhodospirillales 204441|Rhodospirillales E Ornithine cyclodeaminase/mu-crystallin family - - 1.5.1.1,4.3.1.12 ko:K01750,ko:K19743 ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230 - R00671,R01246,R01249,R02201,R02203 RC00135,RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD3_k127_5813113_3 740709.A10D4_05851 7.803e-14 85.0 COG3713@1|root,COG3713@2|Bacteria,1RB2A@1224|Proteobacteria,1S3K6@1236|Gammaproteobacteria 1236|Gammaproteobacteria M MltA-interacting protein MipA - - - ko:K07274 - - - - ko00000,ko02000 9.B.99.1 - - MipA DYD3_k127_5813113_1 314285.KT71_06929 2.798e-39 162.0 COG2358@1|root,COG2358@2|Bacteria,1QPVR@1224|Proteobacteria,1SJP7@1236|Gammaproteobacteria,1J888@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S NMT1-like family - - - - - - - - - - - - NMT1_3 DYD3_k127_5813113_4 247633.GP2143_09907 5.818e-06 56.0 2ATWF@1|root,31JFP@2|Bacteria,1RK55@1224|Proteobacteria,1S6Q1@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_583494_0 323261.Noc_2938 2.53e-172 545.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1WXNW@135613|Chromatiales 135613|Chromatiales E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt DYD3_k127_583494_1 754477.Q7C_2522 2.517e-156 499.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,4605M@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC DYD3_k127_583494_5 519989.ECTPHS_11115 1.898e-67 262.0 COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1WVVA@135613|Chromatiales 135613|Chromatiales NU FimV C-terminal - - - ko:K08086 - - - - ko00000 - - - TPR_19 DYD3_k127_583494_4 1049564.TevJSym_ar00110 7.605e-84 286.0 COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1J4NT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 DYD3_k127_583494_2 395493.BegalDRAFT_1848 3.293e-128 415.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,4600U@72273|Thiotrichales 72273|Thiotrichales I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans DYD3_k127_583494_3 2340.JV46_26490 5.456e-84 292.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1J4MK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_1997,iSDY_1059.SDY_2514 Mur_ligase_C,Mur_ligase_M DYD3_k127_5837501_2 1206733.BAGC01000113_gene7340 1.512e-09 64.0 COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4FZDF@85025|Nocardiaceae 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme - - 4.4.1.15 ko:K05396 ko00270,map00270 - R01874 RC00382 ko00000,ko00001,ko01000 - - - PALP DYD3_k127_5837501_1 570268.ANBB01000008_gene4730 4.339e-29 127.0 COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4EJ7V@85012|Streptosporangiales 201174|Actinobacteria I Phospholipid N-methyltransferase - - - - - - - - - - - - Methyltransf_25,RrnaAD DYD3_k127_5837501_0 1123368.AUIS01000007_gene2702 3.077e-41 158.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,2NCX3@225057|Acidithiobacillales 225057|Acidithiobacillales S L,D-transpeptidase catalytic domain - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - LysM,YkuD DYD3_k127_5841738_1 1266925.JHVX01000003_gene405 1.791e-40 167.0 COG1330@1|root,COG2887@1|root,COG1330@2|Bacteria,COG2887@2|Bacteria,1QU90@1224|Proteobacteria,2VHNR@28216|Betaproteobacteria,37212@32003|Nitrosomonadales 28216|Betaproteobacteria L PD-(D/E)XK nuclease superfamily - - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - PDDEXK_1 DYD3_k127_5841738_0 1120953.AUBH01000004_gene3030 1.751e-143 465.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,465FA@72275|Alteromonadaceae 1236|Gammaproteobacteria C acyl-CoA transferases carnitine dehydratase coaT - - - - - - - - - - - CoA_transf_3 DYD3_k127_5843994_4 326297.Sama_1733 3.739e-12 66.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,2Q8PZ@267890|Shewanellaceae 1236|Gammaproteobacteria E PFAM aminotransferase class I and II aspC - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD3_k127_5843994_0 1121374.KB891576_gene638 2.638e-132 434.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminotransferase aspC - 2.6.1.1,2.6.1.57 ko:K00813,ko:K00832 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00024,M00025,M00034,M00040 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 DYD3_k127_5843994_1 925775.XVE_4830 6.486e-98 328.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1X3E4@135614|Xanthomonadales 135614|Xanthomonadales S Zn-dependent hydrolases including glyoxylases - - - - - - - - - - - - Lactamase_B DYD3_k127_5843994_3 754436.JCM19237_6281 1.015e-22 102.0 2E69Z@1|root,330XW@2|Bacteria,1NC2S@1224|Proteobacteria,1SDZ1@1236|Gammaproteobacteria,1XYJH@135623|Vibrionales 135623|Vibrionales C Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - - - - - - - - - - HIPIP DYD3_k127_5843994_2 1123073.KB899242_gene1636 1.782e-54 208.0 COG3975@1|root,COG3975@2|Bacteria,1N69B@1224|Proteobacteria,1RY45@1236|Gammaproteobacteria,1X82A@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - DYD3_k127_5848519_1 713587.THITH_08540 2.459e-88 301.0 COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria 1236|Gammaproteobacteria GM NmrA-like family - - - - - - - - - - - - NmrA DYD3_k127_5848519_0 565045.NOR51B_1690 3.624e-175 563.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1J54P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C DYD3_k127_5848519_2 247639.MGP2080_04540 2.966e-41 154.0 2CAQ0@1|root,32RRS@2|Bacteria,1RJ3J@1224|Proteobacteria,1S8E9@1236|Gammaproteobacteria,1JB74@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Malonate transporter MadL subunit madL - - - - - - - - - - - MadL DYD3_k127_5848519_3 1196029.ALIM01000020_gene5050 3.778e-08 56.0 28HGK@1|root,2Z7SE@2|Bacteria,1UP9Q@1239|Firmicutes,4HB3M@91061|Bacilli,1ZF4U@1386|Bacillus 91061|Bacilli S Malonate/sodium symporter MadM subunit madM - - - - - - - - - - - MadM DYD3_k127_5869013_1 29581.BW37_04779 1.048e-129 428.0 COG4805@1|root,COG4805@2|Bacteria,1MZDR@1224|Proteobacteria 1224|Proteobacteria S Protein conserved in bacteria - - - - - - - - - - - - - DYD3_k127_5869013_6 1122197.ATWI01000014_gene87 6.778e-51 188.0 COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,46974@72275|Alteromonadaceae 1236|Gammaproteobacteria E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.1.1.104,4.2.1.109 ko:K08964,ko:K22130 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II DYD3_k127_5869013_4 1121939.L861_22120 8.219e-73 258.0 COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria,1XJEE@135619|Oceanospirillales 135619|Oceanospirillales E Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) mtnC - 3.1.3.77 ko:K09880 ko00270,ko01100,map00270,map01100 M00034 R07395 RC02779 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase DYD3_k127_5869013_5 396588.Tgr7_2624 8.19e-70 241.0 COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1X0B2@135613|Chromatiales 135613|Chromatiales S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD - 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - - ARD DYD3_k127_5869013_8 1519464.HY22_00125 5.856e-34 136.0 2DWGT@1|root,34096@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4440 DYD3_k127_5869013_2 296591.Bpro_3668 5.62e-106 350.0 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2VJSY@28216|Betaproteobacteria,4AC5T@80864|Comamonadaceae 28216|Betaproteobacteria P Membrane protein TerC terC - - - - - - - - - - - CBS,CorC_HlyC,TerC DYD3_k127_5869013_3 1537715.JQFJ01000001_gene2724 6.986e-83 291.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TRT9@28211|Alphaproteobacteria,2KCQM@204457|Sphingomonadales 204457|Sphingomonadales E D-amino acid dehydrogenase dadA - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO DYD3_k127_5869013_0 234267.Acid_3236 1.412e-134 447.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria 2|Bacteria G Dehydrogenase - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 DYD3_k127_5901915_0 404589.Anae109_0935 3.289e-134 433.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WKYT@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM Band 7 protein - - - - - - - - - - - - Band_7,Band_7_C DYD3_k127_5901915_3 157783.LK03_08465 2.506e-08 61.0 COG1585@1|root,COG1585@2|Bacteria,1N4FG@1224|Proteobacteria,1S4V9@1236|Gammaproteobacteria 1236|Gammaproteobacteria OU COG1585 Membrane protein implicated in regulation of membrane protease activity - - - ko:K07340 - - - - ko00000 - - - NfeD DYD3_k127_5901915_2 1121439.dsat_0984 4.53e-29 130.0 COG2009@1|root,32QPG@2|Bacteria,1RBGD@1224|Proteobacteria,43DJC@68525|delta/epsilon subdivisions,2X8QN@28221|Deltaproteobacteria,2MHJU@213115|Desulfovibrionales 28221|Deltaproteobacteria C Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt DYD3_k127_5901915_1 485915.Dret_1066 4.231e-131 437.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2M826@213115|Desulfovibrionales 28221|Deltaproteobacteria C TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit sdhA - 1.3.5.1,1.3.5.4 ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD3_k127_5932965_7 64471.sync_2679 6.05e-118 395.0 COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1GZCX@1129|Synechococcus 1117|Cyanobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD3_k127_5932965_8 279238.Saro_1583 6.539e-107 358.0 COG3386@1|root,COG3386@2|Bacteria,1RHPS@1224|Proteobacteria,2UBD9@28211|Alphaproteobacteria 28211|Alphaproteobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - DYD3_k127_5932965_0 279238.Saro_1589 1.077e-318 1004.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTJG@28211|Alphaproteobacteria,2K3KA@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_5932965_11 1522072.IL54_3008 8.543e-71 253.0 COG0657@1|root,COG0657@2|Bacteria,1R61Z@1224|Proteobacteria,2VEWQ@28211|Alphaproteobacteria,2K3XW@204457|Sphingomonadales 204457|Sphingomonadales I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 DYD3_k127_5932965_10 69395.JQLZ01000002_gene1365 4.675e-77 269.0 COG1082@1|root,COG1082@2|Bacteria,1R3UQ@1224|Proteobacteria,2U2AH@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 DYD3_k127_5932965_5 69395.JQLZ01000002_gene1372 2.843e-171 557.0 COG1082@1|root,COG3185@1|root,COG1082@2|Bacteria,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2TRCC@28211|Alphaproteobacteria,2KFJU@204458|Caulobacterales 28211|Alphaproteobacteria C 4-hydroxyphenylpyruvate dioxygenase MA20_22620 - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AP_endonuc_2,Glyoxalase,Glyoxalase_5 DYD3_k127_5932965_2 1353537.TP2_15370 5.931e-209 658.0 COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,2TSSD@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1012 NAD-dependent aldehyde dehydrogenases adhE - 1.2.1.81,1.2.1.87 ko:K13922,ko:K15515 ko00640,map00640 - R09097 RC00004,RC00184 ko00000,ko00001,ko01000 - - - Aldedh DYD3_k127_5932965_1 1353537.TP2_15365 2.054e-280 873.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2XMC7@285107|Thioclava 28211|Alphaproteobacteria EH Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N DYD3_k127_5932965_9 743720.Psefu_2606 8.843e-95 320.0 COG0169@1|root,COG0169@2|Bacteria,1Q95E@1224|Proteobacteria,1S38H@1236|Gammaproteobacteria,1YXQ1@136845|Pseudomonas putida group 1236|Gammaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE2 - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_NADP,Shikimate_DH,Shikimate_dh_N DYD3_k127_5932965_12 1286631.X805_41260 6.21e-62 224.0 COG1309@1|root,COG1309@2|Bacteria,1R5AI@1224|Proteobacteria,2VH3Y@28216|Betaproteobacteria,1KMW6@119065|unclassified Burkholderiales 28216|Betaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_9,TetR_N DYD3_k127_5932965_6 1268622.AVS7_04626 5.026e-120 391.0 COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2VWB8@28216|Betaproteobacteria,4AJA2@80864|Comamonadaceae 28216|Betaproteobacteria C Citrate synthase, C-terminal domain - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD3_k127_5932965_14 1123355.JHYO01000006_gene2273 2.394e-23 105.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,36YCD@31993|Methylocystaceae 28211|Alphaproteobacteria E Dehydroquinase class II aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II DYD3_k127_5932965_13 1177928.TH2_03785 7.759e-50 187.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,2JS4I@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes a trans-dehydration via an enolate intermediate - - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II DYD3_k127_5932965_4 1037409.BJ6T_25820 1.249e-172 557.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2TUA9@28211|Alphaproteobacteria,3JRPT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Carboxylesterase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase DYD3_k127_5932965_3 196367.JNFG01000215_gene783 2.152e-175 560.0 COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2VKBG@28216|Betaproteobacteria,1K17S@119060|Burkholderiaceae 28216|Betaproteobacteria G Major facilitator superfamily MFS_1 - - - ko:K08194 - - - - ko00000,ko02000 2.A.1.14.7 - - MFS_1 DYD3_k127_5932965_15 1121875.KB907558_gene547 3.015e-19 91.0 2EPER@1|root,33H1D@2|Bacteria,4NZ37@976|Bacteroidetes,1I6B9@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_5935372_3 497964.CfE428DRAFT_6140 1.979e-28 132.0 COG0515@1|root,COG0515@2|Bacteria,46UMT@74201|Verrucomicrobia 497964.CfE428DRAFT_6140|- KLT Serine threonine protein kinase - - - - - - - - - - - - - DYD3_k127_5935372_0 1453501.JELR01000001_gene3240 4.917e-76 270.0 28MBM@1|root,2ZAQ2@2|Bacteria,1R5V6@1224|Proteobacteria,1S0K0@1236|Gammaproteobacteria,4662R@72275|Alteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_5935372_5 745014.OMB55_00000760 1.486e-08 66.0 2EDVS@1|root,337QX@2|Bacteria,1NEZW@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_5935372_4 323261.Noc_0677 5.404e-11 69.0 COG3678@1|root,COG3678@2|Bacteria 2|Bacteria NPTU ATP-independent chaperone mediated protein folding - - - ko:K06006 - - - - ko00000,ko03110 - - - LTXXQ,Metal_resist DYD3_k127_5935372_1 1117647.M5M_00760 1.609e-61 221.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMW7@1236|Gammaproteobacteria,1J6AV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain abfR - - ko:K07662 ko01503,ko02020,map01503,map02020 M00447,M00727,M00728 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C DYD3_k127_5935372_2 977880.RALTA_B1809 5.348e-32 137.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2WEJE@28216|Betaproteobacteria,1KHWC@119060|Burkholderiaceae 28216|Betaproteobacteria T Evidence 2a Function of homologous gene experimentally demonstrated in an other organism cpxA - 2.7.13.3 ko:K02484,ko:K07640,ko:K07642 ko01503,ko02020,map01503,map02020 M00447,M00450,M00645,M00646,M00648,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA DYD3_k127_5968405_3 5022.CBX96263 2.221e-09 70.0 KOG2798@1|root,KOG2798@2759|Eukaryota,39TKC@33154|Opisthokonta,3NXZV@4751|Fungi,3QSCR@4890|Ascomycota,203UK@147541|Dothideomycetes,4KHKA@92860|Pleosporales 4751|Fungi G N2227 - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259 2.1.1.22 ko:K19787 ko00340,map00340 - R02144 RC00003,RC00333 ko00000,ko00001,ko01000 - - - N2227 DYD3_k127_5968405_1 1347369.CCAD010000035_gene1038 8.37e-85 291.0 COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,4HI9S@91061|Bacilli,1ZF15@1386|Bacillus 91061|Bacilli I Steryl acetyl hydrolase - - 3.1.1.83 ko:K14731 ko00903,ko00930,ko01220,map00903,map00930,map01220 - R03751,R06390,R06391,R06392,R06393 RC00713,RC00983,RC01505 ko00000,ko00001,ko01000 - - - Abhydrolase_3 DYD3_k127_5968405_2 1198232.CYCME_0772 2.725e-54 192.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,460Y4@72273|Thiotrichales 72273|Thiotrichales C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions fdxA - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4 DYD3_k127_5968405_0 1439940.BAY1663_03067 3.508e-225 720.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate - - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 DYD3_k127_6027467_10 640513.Entas_0686 7.546e-10 63.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,3X0Q6@547|Enterobacter 1236|Gammaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD3_k127_6027467_1 1163408.UU9_02953 1.264e-118 404.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,1X488@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD3_k127_6027467_0 713586.KB900536_gene1379 1.741e-195 625.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales 135613|Chromatiales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase DYD3_k127_6027467_9 62928.azo0877 4.1e-16 83.0 COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria,2KWVG@206389|Rhodocyclales 206389|Rhodocyclales D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic ftsL - - ko:K03586 - - - - ko00000,ko03036 - - - FtsL DYD3_k127_6027467_2 2340.JV46_15920 8.724e-97 325.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1J4C3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 DYD3_k127_6027467_6 1335757.SPICUR_07680 1.548e-61 215.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1WYVR@135613|Chromatiales 135613|Chromatiales K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ DYD3_k127_6027467_8 34506.g3068 2.298e-20 94.0 2D1ZE@1|root,2SJVP@2759|Eukaryota,3AI9D@33154|Opisthokonta,3BX0X@33208|Metazoa,3DEMU@33213|Bilateria 33208|Metazoa S LppC putative lipoprotein - - - - - - - - - - - - LppC DYD3_k127_6027467_3 396588.Tgr7_0758 7.204e-89 301.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria,1WWCD@135613|Chromatiales 135613|Chromatiales H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase DYD3_k127_6027467_4 472759.Nhal_0475 2.073e-86 310.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales 135613|Chromatiales M PFAM LppC - - - ko:K07121 - - - - ko00000 - - - LppC DYD3_k127_6027467_7 393595.ABO_0585 7.551e-30 122.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1XM4S@135619|Oceanospirillales 135619|Oceanospirillales L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 DYD3_k127_6027467_5 232346.JHQL01000003_gene297 2.771e-68 238.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1XI6S@135619|Oceanospirillales 135619|Oceanospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 DYD3_k127_6046666_1 1390370.O203_16810 4.089e-54 198.0 COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,1YFFN@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux DYD3_k127_6046666_2 243233.MCA1564 1.844e-38 160.0 2DM5E@1|root,31SVN@2|Bacteria,1MYKR@1224|Proteobacteria,1SF2N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 DYD3_k127_6046666_0 69395.JQLZ01000001_gene3017 3.187e-149 487.0 COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,2U6FF@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Sugar phosphate permease uhpC - - ko:K02445 - - - - ko00000,ko02000 2.A.1.4.3 - - MFS_1 DYD3_k127_6046666_3 491952.Mar181_1053 1.301e-36 147.0 COG1011@1|root,COG1011@2|Bacteria,1QSY2@1224|Proteobacteria,1RWK3@1236|Gammaproteobacteria,1XM90@135619|Oceanospirillales 135619|Oceanospirillales S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - 3.1.3.10 ko:K20866 ko00010,ko01120,map00010,map01120 - R00947 RC00078 ko00000,ko00001,ko01000 - - - HAD_2 DYD3_k127_6046666_5 1121875.KB907547_gene3035 1.778e-05 53.0 2EM9G@1|root,33EYK@2|Bacteria,4P33X@976|Bacteroidetes,1I90G@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_6046666_4 543728.Vapar_3776 4.567e-29 118.0 COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2VHS8@28216|Betaproteobacteria,4ACWG@80864|Comamonadaceae 28216|Betaproteobacteria M Belongs to the aspartate glutamate racemases family - - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race DYD3_k127_6050018_3 935567.JAES01000003_gene178 6.982e-42 155.0 COG0662@1|root,COG0662@2|Bacteria,1R4UW@1224|Proteobacteria,1S3Z7@1236|Gammaproteobacteria,1X680@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO DYD3_k127_6050018_0 523791.Kkor_0379 1.395e-155 496.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,1RX6Z@1236|Gammaproteobacteria,1XRR2@135619|Oceanospirillales 135619|Oceanospirillales S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 DYD3_k127_6050018_1 1122176.KB903587_gene4458 2.777e-149 484.0 COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1IQ2Y@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 DYD3_k127_6050018_2 1144275.COCOR_00866 1.014e-116 392.0 COG0654@1|root,COG0654@2|Bacteria,1R7UC@1224|Proteobacteria 1224|Proteobacteria H Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid kmo GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 DYD3_k127_605296_11 1163408.UU9_00075 1.79e-38 154.0 2ARAV@1|root,31GKV@2|Bacteria,1QEAT@1224|Proteobacteria,1TAVS@1236|Gammaproteobacteria,1X8YF@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - Esterase_phd DYD3_k127_605296_9 1268239.PALB_6750 3.222e-53 190.0 COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,1RMG4@1236|Gammaproteobacteria,2Q17N@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T Carbon starvation protein cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM DYD3_k127_605296_1 1298865.H978DRAFT_3856 1.695e-198 625.0 COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,1RMG4@1236|Gammaproteobacteria,465XE@72275|Alteromonadaceae 1236|Gammaproteobacteria T Carbon starvation protein cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM DYD3_k127_605296_5 864051.BurJ1DRAFT_2776 6.304e-126 421.0 COG2010@1|root,COG2010@2|Bacteria,1R1VN@1224|Proteobacteria,2WI66@28216|Betaproteobacteria,1KN79@119065|unclassified Burkholderiales 28216|Betaproteobacteria C HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 DYD3_k127_605296_4 1379270.AUXF01000003_gene3622 1.647e-158 517.0 COG3391@1|root,COG3391@2|Bacteria,1ZSNC@142182|Gemmatimonadetes 142182|Gemmatimonadetes S amine dehydrogenase activity - - - - - - - - - - - - - DYD3_k127_605296_8 941449.dsx2_3134 1.828e-64 230.0 COG2080@1|root,COG2080@2|Bacteria,1N1KQ@1224|Proteobacteria,42UD3@68525|delta/epsilon subdivisions,2WPH9@28221|Deltaproteobacteria,2M9N0@213115|Desulfovibrionales 28221|Deltaproteobacteria C 2Fe-2S -binding - - - - - - - - - - - - Fer2,Fer2_2 DYD3_k127_605296_0 941449.dsx2_3133 4.774e-201 653.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MAGR@213115|Desulfovibrionales 28221|Deltaproteobacteria C xanthine dehydrogenase a b hammerhead - - 1.17.1.4 ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2 DYD3_k127_605296_6 596152.DesU5LDRAFT_2640 9.624e-115 379.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2M9BS@213115|Desulfovibrionales 28221|Deltaproteobacteria C PFAM Molybdopterin dehydrogenase, FAD-binding - - 1.17.1.4 ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 DYD3_k127_605296_13 264198.Reut_A0685 1.672e-07 61.0 COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,1K1V2@119060|Burkholderiaceae 28216|Betaproteobacteria C formate dehydrogenase fdhC - - ko:K00127 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Ni_hydr_CYTB DYD3_k127_605296_12 596152.DesU5LDRAFT_2642 2.91e-17 85.0 2AHM7@1|root,317Z3@2|Bacteria,1PZHH@1224|Proteobacteria,435Z7@68525|delta/epsilon subdivisions,2X0GI@28221|Deltaproteobacteria,2MC94@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_605296_2 1129794.C427_3115 1.73e-174 563.0 COG1231@1|root,COG1231@2|Bacteria,1MWPH@1224|Proteobacteria,1RPNY@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Monoamine oxidase lao - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase DYD3_k127_605296_10 1129794.C427_3114 2.803e-49 190.0 COG2863@1|root,COG2863@2|Bacteria,1QXWH@1224|Proteobacteria,1T3IQ@1236|Gammaproteobacteria,468V6@72275|Alteromonadaceae 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,ThuA DYD3_k127_605296_7 1129794.C427_3113 5.969e-72 245.0 COG0251@1|root,COG0251@2|Bacteria,1RD3E@1224|Proteobacteria,1S6NI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Translation Initiation Inhibitor YjgF Family tdcF - - - - - - - - - - - Ribonuc_L-PSP DYD3_k127_605296_3 1283300.ATXB01000001_gene392 3.657e-163 520.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 DYD3_k127_6055565_3 550540.Fbal_2268 8.46e-28 117.0 COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria L methylated DNA-protein cysteine methyltransferase ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - ko:K07443 - - - - ko00000 - - - DNA_binding_1 DYD3_k127_6055565_0 870187.Thini_0482 2.923e-148 483.0 COG1100@1|root,COG1100@2|Bacteria,1R1W9@1224|Proteobacteria,1SK3H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF697) - - - - - - - - - - - - DUF697,MMR_HSR1 DYD3_k127_6055565_1 1123401.JHYQ01000003_gene2117 2.939e-113 383.0 COG1100@1|root,COG1100@2|Bacteria,1QXSV@1224|Proteobacteria,1S5FA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 50S ribosome-binding GTPase - - - ko:K06883 - - - - ko00000 - - - DUF697,MMR_HSR1 DYD3_k127_6055565_4 1537994.JQFW01000056_gene647 3.594e-27 119.0 2DN4B@1|root,32VFQ@2|Bacteria,1QYAE@1224|Proteobacteria,1T3N3@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2490) - - - - - - - - - - - - DUF2490 DYD3_k127_6055565_2 1121015.N789_09310 4.132e-51 187.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1X4AQ@135614|Xanthomonadales 135614|Xanthomonadales M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly DYD3_k127_6057424_1 1408445.JHXP01000012_gene2434 2.781e-37 156.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1JDBU@118969|Legionellales 118969|Legionellales C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD3_k127_6057424_0 1442599.JAAN01000024_gene1857 0.0 1060.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1X4NM@135614|Xanthomonadales 135614|Xanthomonadales C E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr DYD3_k127_6066724_3 1131812.JQMS01000001_gene1669 1.048e-42 160.0 COG0346@1|root,COG0346@2|Bacteria,4NSC9@976|Bacteroidetes,1I32P@117743|Flavobacteriia 976|Bacteroidetes E Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase DYD3_k127_6066724_1 1197906.CAJQ02000023_gene2405 6.168e-122 396.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,3JRRG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V transport, permease protein yadH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane DYD3_k127_6066724_0 1192868.CAIU01000013_gene1747 1.279e-142 460.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,43HHC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V ABC transporter hndI GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_6066724_2 926561.KB900623_gene941 1.946e-69 263.0 COG1538@1|root,COG1538@2|Bacteria 2|Bacteria MU efflux transmembrane transporter activity - - - - - - - - - - - - ABC_sub_bind,OEP DYD3_k127_6070990_1 330214.NIDE0941 4.394e-74 266.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 DYD3_k127_6070990_0 395493.BegalDRAFT_3010 6.301e-98 326.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,462JT@72273|Thiotrichales 72273|Thiotrichales T Transcriptional regulatory protein, C terminal - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C DYD3_k127_6070990_2 1121937.AUHJ01000003_gene3229 9.205e-25 108.0 COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - CBM9_1,HATPase_c,HisKA DYD3_k127_6086993_4 153948.NAL212_3012 6.045e-05 46.0 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,373A7@32003|Nitrosomonadales 28216|Betaproteobacteria H diol metabolic process - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a DYD3_k127_6086993_2 1336233.JAEH01000041_gene4328 1.328e-20 102.0 COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S8BF@1236|Gammaproteobacteria,2Q8IY@267890|Shewanellaceae 1236|Gammaproteobacteria M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_YMGG,OmpA DYD3_k127_6086993_1 566466.NOR53_416 1.914e-90 309.0 COG2304@1|root,COG2304@2|Bacteria,1QBPM@1224|Proteobacteria,1RQIU@1236|Gammaproteobacteria,1J4PZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Secreted protein, containing von Willebrand factor (VWF) type - - - - - - - - - - - - - DYD3_k127_6086993_0 1453501.JELR01000001_gene3246 4.161e-91 312.0 COG1196@1|root,COG1196@2|Bacteria,1R4BS@1224|Proteobacteria,1S13B@1236|Gammaproteobacteria,466JA@72275|Alteromonadaceae 1236|Gammaproteobacteria D von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA_2 DYD3_k127_6086993_3 102125.Xen7305DRAFT_00023510 2.855e-05 51.0 COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,3VI20@52604|Pleurocapsales 1117|Cyanobacteria V ABC-type multidrug transport system ATPase component - - - - - - - - - - - - ABC2_membrane,ABC_tran,FHA DYD3_k127_6087529_0 1278073.MYSTI_00047 6.911e-129 421.0 COG3386@1|root,COG3386@2|Bacteria,1NIN4@1224|Proteobacteria 1224|Proteobacteria G Major royal jelly protein - - - - - - - - - - - - MRJP DYD3_k127_6087529_1 1121939.L861_15500 1.138e-48 179.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1XI57@135619|Oceanospirillales 135619|Oceanospirillales M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix DYD3_k127_6093172_3 1116472.MGMO_60c00140 7.974e-149 477.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XDR0@135618|Methylococcales 135618|Methylococcales J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b DYD3_k127_6093172_0 1042377.AFPJ01000020_gene2040 7.288e-245 769.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,465WS@72275|Alteromonadaceae 1236|Gammaproteobacteria E Gamma-glutamyltranspeptidase ggt_2 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept DYD3_k127_6093172_4 1385515.N791_03160 1.884e-130 431.0 COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,1X3Z6@135614|Xanthomonadales 135614|Xanthomonadales E Splits dipeptides with a prolyl residue in the C- terminal position pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD3_k127_6093172_7 502025.Hoch_5167 1.222e-86 294.0 COG0300@1|root,COG0300@2|Bacteria,1PG5S@1224|Proteobacteria,43473@68525|delta/epsilon subdivisions,2X263@28221|Deltaproteobacteria,2YXTC@29|Myxococcales 28221|Deltaproteobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short DYD3_k127_6093172_15 1500893.JQNB01000001_gene1736 3.039e-53 190.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1X6D2@135614|Xanthomonadales 135614|Xanthomonadales J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 DYD3_k127_6093172_2 1149133.ppKF707_4545 5.326e-149 477.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1YCXZ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L DYD3_k127_6093172_6 519989.ECTPHS_13178 3.636e-93 309.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 DYD3_k127_6093172_14 28258.KP05_11875 3.689e-62 215.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,1XJQU@135619|Oceanospirillales 135619|Oceanospirillales J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 DYD3_k127_6093172_16 1123399.AQVE01000003_gene2023 2.905e-51 184.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,460PX@72273|Thiotrichales 72273|Thiotrichales J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 DYD3_k127_6093172_27 177416.FTT_0346 4.818e-13 70.0 COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria,461DS@72273|Thiotrichales 72273|Thiotrichales J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 DYD3_k127_6093172_1 76114.ebA3846 5.115e-173 554.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,2KVBF@206389|Rhodocyclales 206389|Rhodocyclales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY DYD3_k127_6093172_18 305900.GV64_22985 7.768e-46 169.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XJJ2@135619|Oceanospirillales 135619|Oceanospirillales J Binds to the 23S rRNA rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A DYD3_k127_6093172_25 857087.Metme_3798 6.554e-17 82.0 COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1XFTY@135618|Methylococcales 135618|Methylococcales J Ribosomal protein L30 rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 DYD3_k127_6093172_12 566466.NOR53_394 2.631e-68 236.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1J5S0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C DYD3_k127_6093172_20 243233.MCA2356 2.068e-40 152.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1XFB0@135618|Methylococcales 135618|Methylococcales J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p DYD3_k127_6093172_11 1286106.MPL1_09747 1.074e-69 240.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,460IG@72273|Thiotrichales 72273|Thiotrichales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 DYD3_k127_6093172_17 519989.ECTPHS_13128 2.016e-48 177.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1WXYT@135613|Chromatiales 135613|Chromatiales J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 DYD3_k127_6093172_23 1122207.MUS1_04890 3.206e-33 130.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1XKDP@135619|Oceanospirillales 135619|Oceanospirillales J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 DYD3_k127_6093172_8 765911.Thivi_4213 2.231e-81 273.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1WW32@135613|Chromatiales 135613|Chromatiales J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C DYD3_k127_6093172_21 1415780.JPOG01000001_gene2154 1.578e-38 147.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1X6UR@135614|Xanthomonadales 135614|Xanthomonadales J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 DYD3_k127_6093172_13 90814.KL370891_gene244 2.016e-63 218.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,460HS@72273|Thiotrichales 72273|Thiotrichales J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN - - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 DYD3_k127_6093172_24 1283300.ATXB01000001_gene621 1.19e-27 114.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1XFGP@135618|Methylococcales 135618|Methylococcales J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 DYD3_k127_6093172_26 1033802.SSPSH_003096 5.096e-16 81.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 DYD3_k127_6093172_9 998674.ATTE01000001_gene4288 7.191e-72 244.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,460I6@72273|Thiotrichales 72273|Thiotrichales J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP - - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 DYD3_k127_6093172_5 1123399.AQVE01000003_gene2038 8.173e-98 326.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,45ZXA@72273|Thiotrichales 72273|Thiotrichales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C DYD3_k127_6093172_22 765914.ThisiDRAFT_1683 9.949e-38 144.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1WYH7@135613|Chromatiales 135613|Chromatiales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 DYD3_k127_6093172_19 765910.MARPU_03740 5.089e-42 155.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1WYHJ@135613|Chromatiales 135613|Chromatiales J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS - - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 DYD3_k127_6093172_10 1265313.HRUBRA_02465 9.548e-72 244.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1J4FI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C DYD3_k127_611978_7 402881.Plav_2665 4.555e-51 185.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,1JN1E@119043|Rhodobiaceae 28211|Alphaproteobacteria J DALR_2 cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e DYD3_k127_611978_10 195105.CN97_10080 1.095e-27 114.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane yidD - - ko:K08998 - - - - ko00000 - - - Haemolytic DYD3_k127_611978_11 247633.GP2143_11387 3.305e-17 87.0 2E2R2@1|root,32XTN@2|Bacteria,1NHQU@1224|Proteobacteria,1T6A2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S MerC mercury resistance protein - - - - - - - - - - - - MerC DYD3_k127_611978_12 59374.Fisuc_2743 3.253e-16 81.0 COG2835@1|root,COG2835@2|Bacteria 2|Bacteria EG tetraacyldisaccharide 4'-kinase activity - - - ko:K09791 - - - - ko00000 - - - Methyltransf_25,Trm112p DYD3_k127_611978_3 498211.CJA_0452 1.259e-88 303.0 COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1FGH0@10|Cellvibrio 1236|Gammaproteobacteria L DNA polymerase III, delta subunit holA GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delt_C,DNA_pol3_delta DYD3_k127_611978_5 396588.Tgr7_2275 2.053e-66 233.0 COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1WY6R@135613|Chromatiales 135613|Chromatiales H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like DYD3_k127_611978_9 1137799.GZ78_04715 9.116e-39 147.0 COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1XKG3@135619|Oceanospirillales 135619|Oceanospirillales J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS DYD3_k127_611978_8 396588.Tgr7_2273 7.585e-42 158.0 COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1WY5P@135613|Chromatiales 135613|Chromatiales J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase DYD3_k127_611978_6 765912.Thimo_2599 6.926e-52 191.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1WY2J@135613|Chromatiales 135613|Chromatiales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf DYD3_k127_611978_0 870187.Thini_3905 8.566e-176 564.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,45ZW6@72273|Thiotrichales 72273|Thiotrichales J ribonuclease, Rne Rng family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD3_k127_611978_2 472759.Nhal_0546 5.582e-128 453.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1WXQJ@135613|Chromatiales 135613|Chromatiales S Protein of unknown function - - - - - - - - - - - - AsmA_2,DUF3971 DYD3_k127_611978_4 1122604.JONR01000007_gene2842 8.784e-85 289.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1X664@135614|Xanthomonadales 135614|Xanthomonadales S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase DYD3_k127_611978_1 765912.Thimo_2604 3.733e-137 444.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD DYD3_k127_6120010_12 1502770.JQMG01000001_gene2030 2.36e-35 138.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2VMJ9@28216|Betaproteobacteria 28216|Betaproteobacteria O assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 DYD3_k127_6120010_3 483219.LILAB_02825 9.632e-169 540.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales 28221|Deltaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 DYD3_k127_6120010_10 381666.H16_B1516 9.837e-43 168.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ3A@28216|Betaproteobacteria,1K7JP@119060|Burkholderiaceae 28216|Betaproteobacteria C NifU-like N terminal domain - - - ko:K04488 - - - - ko00000 - - - NifU_N DYD3_k127_6120010_8 935863.AWZR01000013_gene1523 9.157e-74 252.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales 135614|Xanthomonadales S FeS assembly SUF system protein SufT - - - - - - - - - - - - FeS_assembly_P DYD3_k127_6120010_11 709032.Sulku_1674 6.458e-41 157.0 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,42TJ0@68525|delta/epsilon subdivisions,2YPZ4@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria T phosphohistidine phosphatase, SixA sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 DYD3_k127_6120010_0 1300345.LF41_1668 0.0 1153.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1X36U@135614|Xanthomonadales 135614|Xanthomonadales CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg DYD3_k127_6120010_1 525897.Dbac_2687 9.861e-176 559.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2MA8W@213115|Desulfovibrionales 28221|Deltaproteobacteria E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide kbl - 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2,BioW DYD3_k127_6120010_2 1268239.PALB_3350 2.077e-170 544.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,2Q021@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_3926,iECUMN_1333.ECUMN_4133,iPC815.YPO0060 ADH_N,ADH_zinc_N DYD3_k127_6120010_5 223926.28807145 1.034e-145 482.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1XT9K@135623|Vibrionales 135623|Vibrionales OU signal peptide peptidase sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 DYD3_k127_6120010_4 1121918.ARWE01000001_gene966 1.067e-157 507.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,43S8N@69541|Desulfuromonadales 28221|Deltaproteobacteria G PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - - - - - - - - - - DctM,DctQ DYD3_k127_6120010_13 1121918.ARWE01000001_gene965 5.512e-30 128.0 COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,42TZJ@68525|delta/epsilon subdivisions,2WQB8@28221|Deltaproteobacteria 28221|Deltaproteobacteria G PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - - - - - - - - - - DctQ DYD3_k127_6120010_6 1121918.ARWE01000001_gene964 1.157e-77 273.0 COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria 28221|Deltaproteobacteria G PFAM TRAP dicarboxylate transporter- DctP subunit - - - - - - - - - - - - DctP DYD3_k127_6120010_7 580332.Slit_0818 1.018e-76 267.0 COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,2VWPY@28216|Betaproteobacteria 28216|Betaproteobacteria S TRAP transporter T-component - - - - - - - - - - - - TAtT DYD3_k127_6120010_9 765910.MARPU_07340 1.147e-53 190.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1WYID@135613|Chromatiales 135613|Chromatiales J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 DYD3_k127_6141545_1 1046714.AMRX01000001_gene1412 2.241e-173 556.0 COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,1RQ1S@1236|Gammaproteobacteria,464Q7@72275|Alteromonadaceae 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.135 ko:K21575 - - - - ko00000,ko01000 - GH13 - Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N DYD3_k127_6141545_0 498211.CJA_0736 5.034e-228 718.0 COG1082@1|root,COG1082@2|Bacteria,1NNTS@1224|Proteobacteria,1RP3I@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Alpha-glucosidase - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - GH97_C,GH97_N,Glyco_hydro_97 DYD3_k127_6153238_2 1122137.AQXF01000001_gene2567 8.934e-114 381.0 COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria 1224|Proteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase,DUF3471 DYD3_k127_6153238_1 301.JNHE01000044_gene3840 2.106e-149 488.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1YD4C@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I Phospholipase D. Active site motifs. - - - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD3_k127_6153238_0 1163408.UU9_03932 9.623e-163 523.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K12980 - - - - ko00000,ko01005 - - - OMP_b-brl,Surface_Ag_2 DYD3_k127_6153238_3 652103.Rpdx1_4878 1.124e-63 219.0 COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2TV6R@28211|Alphaproteobacteria,3JWGS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold ligC - 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C DYD3_k127_6158154_0 314285.KT71_09572 1.643e-291 907.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1S0CZ@1236|Gammaproteobacteria,1J9C3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C related to penicillin acylase - - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase DYD3_k127_6163934_2 1380394.JADL01000010_gene4401 2.577e-33 132.0 COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria,2JW6C@204441|Rhodospirillales 204441|Rhodospirillales I Enoyl-CoA hydratase/isomerase - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 DYD3_k127_6163934_0 399739.Pmen_0123 2.292e-106 357.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RPCH@1236|Gammaproteobacteria,1YKMU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria BQ Histone deacetylase domain aphA - - - - - - - - - - - Hist_deacetyl DYD3_k127_6163934_1 1123257.AUFV01000003_gene817 3.916e-44 168.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1X37B@135614|Xanthomonadales 135614|Xanthomonadales G PQQ-like domain - - - - - - - - - - - - Cytochrome_CBB3,PQQ DYD3_k127_6170790_2 1304275.C41B8_09151 2.71e-55 199.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N DYD3_k127_6170790_1 349124.Hhal_0946 8.646e-68 241.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1WWVS@135613|Chromatiales 135613|Chromatiales E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer DYD3_k127_6170790_5 1247024.JRLH01000006_gene2737 2.813e-25 112.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT DYD3_k127_6170790_6 1384056.N787_12570 3.571e-25 111.0 2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1X82G@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4426) - - - - - - - - - - - - DUF4426 DYD3_k127_6170790_4 713586.KB900536_gene1715 2.417e-31 127.0 COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Belongs to the bacterial histone-like protein family VL23_14575 - - - - - - - - - - - Bac_DNA_binding DYD3_k127_6170790_3 1123073.KB899241_gene2657 2.884e-51 191.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S6R4@1236|Gammaproteobacteria,1XC0H@135614|Xanthomonadales 135614|Xanthomonadales S X-Pro dipeptidyl-peptidase (S15 family) - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4 DYD3_k127_6170790_0 105559.Nwat_1417 1.435e-182 579.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales 135613|Chromatiales E PFAM Aminotransferase class-III - - 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 DYD3_k127_6170790_7 1317118.ATO8_16078 1.132e-12 80.0 COG1905@1|root,COG3743@1|root,COG1905@2|Bacteria,COG3743@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,4KM99@93682|Roseivivax 28211|Alphaproteobacteria C Thioredoxin-like [2Fe-2S] ferredoxin nuoE - 1.6.5.3,1.6.99.3 ko:K00334,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 - - 2Fe-2S_thioredx DYD3_k127_6180683_5 66373.JOFQ01000036_gene2763 1.456e-54 198.0 COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria 201174|Actinobacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 DYD3_k127_6180683_1 765911.Thivi_0086 1.035e-163 527.0 COG1055@1|root,COG1055@2|Bacteria,1QMWD@1224|Proteobacteria,1TK7C@1236|Gammaproteobacteria,1X05Y@135613|Chromatiales 135613|Chromatiales P Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - - - - - - - - - - - DYD3_k127_6180683_6 1173020.Cha6605_6181 1.475e-37 145.0 COG0454@1|root,COG0456@2|Bacteria,1G7IH@1117|Cyanobacteria 1117|Cyanobacteria K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 DYD3_k127_6180683_3 384765.SIAM614_05573 2.205e-142 465.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria 28211|Alphaproteobacteria M mechanosensitive ion channel MA20_40450 - - - - - - - - - - - MS_channel DYD3_k127_6180683_2 565045.NOR51B_1907 7.88e-163 529.0 COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG0659 Sulfate permease and related transporters (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp DYD3_k127_6180683_0 1121374.KB891575_gene1184 1.186e-208 655.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1S5FN@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Radical SAM superfamily - - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,LAM_C,Radical_SAM DYD3_k127_6180683_4 1121374.KB891575_gene1185 4.624e-137 441.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,1SKJ8@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C DYD3_k127_618824_4 1453501.JELR01000002_gene1259 1.679e-12 67.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,46468@72275|Alteromonadaceae 1236|Gammaproteobacteria E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - - - - - - - - - - Peptidase_S9 DYD3_k127_618824_2 1207063.P24_13208 1.425e-131 428.0 COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,2JPJQ@204441|Rhodospirillales 204441|Rhodospirillales E Pyridoxal-phosphate dependent enzyme - - - - - - - - - - - - PALP DYD3_k127_618824_3 1265313.HRUBRA_02713 6.387e-58 214.0 COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,1RMHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the aspartate glutamate racemases family - - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race DYD3_k127_618824_0 1122137.AQXF01000003_gene2417 1.588e-212 681.0 COG2234@1|root,COG2234@2|Bacteria,1NVWC@1224|Proteobacteria 1224|Proteobacteria S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 DYD3_k127_618824_1 1121104.AQXH01000003_gene415 5.201e-149 479.0 COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1IV0D@117747|Sphingobacteriia 976|Bacteroidetes E Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 DYD3_k127_6190663_0 1042377.AFPJ01000024_gene754 2.912e-82 284.0 COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,1RNI5@1236|Gammaproteobacteria,467KI@72275|Alteromonadaceae 1236|Gammaproteobacteria T Anti-ECFsigma factor ChrR - - - - - - - - - - - - Cupin_7 DYD3_k127_6190663_1 1121374.KB891589_gene110 4.252e-74 250.0 2BDUH@1|root,302AN@2|Bacteria,1RF2Q@1224|Proteobacteria 1224|Proteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA DYD3_k127_6190663_2 204669.Acid345_4117 9.477e-44 169.0 COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia 204432|Acidobacteriia KLT Tetratricopeptide repeats - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C DYD3_k127_622184_2 1211114.ALIP01000091_gene2834 3.777e-11 68.0 COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,1S95H@1236|Gammaproteobacteria,1X5RN@135614|Xanthomonadales 135614|Xanthomonadales G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - DYD3_k127_622184_0 765910.MARPU_00500 1.907e-147 479.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria,1WXUS@135613|Chromatiales 135613|Chromatiales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD3_k127_622184_1 493475.GARC_0305 1.742e-15 80.0 COG0454@1|root,COG0456@2|Bacteria,1QZ7S@1224|Proteobacteria,1T40Z@1236|Gammaproteobacteria,46D80@72275|Alteromonadaceae 1236|Gammaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD3_k127_6232885_4 323261.Noc_1528 8.313e-42 160.0 COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1X17T@135613|Chromatiales 135613|Chromatiales MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP DYD3_k127_6232885_0 331869.BAL199_11346 8.882e-89 304.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,4BPX1@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G PFAM pfkB family carbohydrate kinase pfkB - 2.7.1.20,2.7.1.4 ko:K00847,ko:K00856 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 - R00185,R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB DYD3_k127_6232885_5 291985.CCSI01000007_gene461 1.491e-25 115.0 2FGC9@1|root,3488G@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4956) - - - - - - - - - - - - DUF4956 DYD3_k127_6232885_6 1392488.JHZY01000004_gene2619 3.255e-13 82.0 COG3204@1|root,COG3204@2|Bacteria,4NNIP@976|Bacteroidetes,1I2A1@117743|Flavobacteriia,2XJ72@283735|Leeuwenhoekiella 976|Bacteroidetes S SdiA-regulated - - - - - - - - - - - - SdiA-regulated DYD3_k127_6232885_1 672.VV93_v1c31510 1.334e-65 237.0 COG1404@1|root,COG1404@2|Bacteria,1R5Y1@1224|Proteobacteria,1SEMA@1236|Gammaproteobacteria,1XU06@135623|Vibrionales 135623|Vibrionales O Subtilisin-like serine - - - - - - - - - - - - - DYD3_k127_6232885_2 247639.MGP2080_00745 1.617e-60 222.0 28M5H@1|root,2ZAJ9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_6232885_3 247634.GPB2148_3272 1.597e-55 204.0 COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - - - - - - - - - - Metallophos DYD3_k127_6233116_2 1123073.KB899241_gene2608 1.594e-16 84.0 COG1595@1|root,COG1595@2|Bacteria,1RI1M@1224|Proteobacteria,1S780@1236|Gammaproteobacteria,1X678@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_6233116_1 1123279.ATUS01000001_gene614 1.347e-54 199.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1J5VZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F ADP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX,Nudix_N_2 DYD3_k127_6233116_0 1123256.KB907928_gene2064 2.974e-58 213.0 COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1X3T4@135614|Xanthomonadales 135614|Xanthomonadales O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process dsbC - 5.3.4.1 ko:K03981 - - - - ko00000,ko01000,ko02044,ko03110 3.A.7.11.1 - - DsbC_N,Thioredoxin_2 DYD3_k127_624231_5 1265503.KB905173_gene4132 8.695e-08 61.0 COG3595@1|root,COG3595@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4097 DYD3_k127_624231_2 471854.Dfer_1127 1.751e-24 114.0 COG3595@1|root,COG3595@2|Bacteria,4NJBA@976|Bacteroidetes,47MRP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_624231_3 929562.Emtol_2537 2.743e-13 79.0 COG1413@1|root,COG1413@2|Bacteria,4NIBA@976|Bacteroidetes,47M5K@768503|Cytophagia 976|Bacteroidetes C HEAT repeats - - - - - - - - - - - - HEAT_2,zf-HC2 DYD3_k127_624231_1 1121957.ATVL01000012_gene614 9.139e-28 119.0 COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_624231_0 1121937.AUHJ01000001_gene315 8.932e-175 561.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,4657F@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD3_k127_6259270_7 768066.HELO_4139 2.137e-08 56.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1XJNA@135619|Oceanospirillales 135619|Oceanospirillales S Required for maturation of 30S ribosomal subunits rimP - - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C DYD3_k127_6259270_2 396588.Tgr7_1002 9.681e-220 691.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales 135613|Chromatiales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 DYD3_k127_6259270_1 472759.Nhal_2771 2.278e-277 876.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales 135613|Chromatiales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc DYD3_k127_6259270_6 519989.ECTPHS_07252 2.026e-24 106.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1WYHM@135613|Chromatiales 135613|Chromatiales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA DYD3_k127_6259270_3 187272.Mlg_1946 3.789e-78 271.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales 135613|Chromatiales J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N DYD3_k127_6259270_4 519989.ECTPHS_07262 2.674e-34 134.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1WYZR@135613|Chromatiales 135613|Chromatiales J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 DYD3_k127_6259270_0 1255043.TVNIR_3106 0.0 1006.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales 135613|Chromatiales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 DYD3_k127_6259270_5 392500.Swoo_0670 4.419e-32 127.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,2QAZU@267890|Shewanellaceae 1236|Gammaproteobacteria S PFAM alpha beta hydrolase fold yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 DYD3_k127_6260642_8 521045.Kole_0146 1.153e-104 357.0 COG1168@1|root,COG1168@2|Bacteria,2GCM9@200918|Thermotogae 200918|Thermotogae E aminotransferase class I and II - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Acetyltransf_10,Aminotran_1_2 DYD3_k127_6260642_5 742738.HMPREF9460_04204 1.913e-127 425.0 COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,26AAW@186813|unclassified Clostridiales 186801|Clostridia C Na+/H+ antiporter family - - - - - - - - - - - - Na_H_antiporter DYD3_k127_6260642_9 1379270.AUXF01000001_gene1910 4.177e-88 299.0 COG0179@1|root,COG0179@2|Bacteria,1ZTIG@142182|Gemmatimonadetes 2|Bacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - DUF2437,FAA_hydrolase DYD3_k127_6260642_6 234267.Acid_2447 2.228e-124 407.0 COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria 57723|Acidobacteria S NHL repeat - - - - - - - - - - - - NHL DYD3_k127_6260642_2 765913.ThidrDRAFT_1373 7.131e-181 574.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1WX7U@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b DYD3_k127_6260642_1 1357272.AVEO02000077_gene4618 5.739e-184 586.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1Z6R5@136849|Pseudomonas syringae group 1236|Gammaproteobacteria L AAA C-terminal domain rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N DYD3_k127_6260642_13 1163408.UU9_08710 2.622e-08 60.0 2DRS8@1|root,33CUB@2|Bacteria,1QV1W@1224|Proteobacteria,1T26B@1236|Gammaproteobacteria 1236|Gammaproteobacteria S VanZ like family - - - - - - - - - - - - VanZ DYD3_k127_6260642_11 1286106.MPL1_06477 1.57e-39 159.0 COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,460XC@72273|Thiotrichales 72273|Thiotrichales M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - ko:K03634 - - - - ko00000 - - - LolA DYD3_k127_6260642_0 713586.KB900536_gene612 2.194e-282 887.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales 135613|Chromatiales D DNA segregation ATPase FtsK SpoIIIE - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma DYD3_k127_6260642_3 765910.MARPU_11570 3.448e-156 499.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales 135613|Chromatiales C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD3_k127_6260642_7 857087.Metme_0938 1.218e-111 376.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1XDVT@135618|Methylococcales 135618|Methylococcales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like DYD3_k127_6260642_10 545276.KB898731_gene2140 3.043e-72 254.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1WWJ2@135613|Chromatiales 135613|Chromatiales O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat - 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans DYD3_k127_6260642_12 2340.JV46_21250 1.265e-35 137.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1J6G9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a DYD3_k127_6260642_4 472759.Nhal_2275 5.455e-135 434.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales 135613|Chromatiales O Belongs to the ClpA ClpB family clpA - - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N DYD3_k127_6272179_2 420662.Mpe_A0661 1.224e-22 109.0 COG3290@1|root,COG3447@1|root,COG5001@1|root,COG3290@2|Bacteria,COG3447@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria 1224|Proteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,MASE1,PAS,PAS_4,PAS_9 DYD3_k127_6272179_0 519989.ECTPHS_01624 8.178e-55 200.0 COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1WX4D@135613|Chromatiales 135613|Chromatiales O PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT DYD3_k127_6272179_1 338969.Rfer_2603 1.435e-24 113.0 COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria,4AEZQ@80864|Comamonadaceae 28216|Betaproteobacteria P SMART Rhodanese domain protein pspE2 - - - - - - - - - - - Rhodanese DYD3_k127_6272179_3 396588.Tgr7_0483 0.0001744 49.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1WVXZ@135613|Chromatiales 135613|Chromatiales MU type I secretion outer membrane protein, TolC - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP DYD3_k127_6273608_0 382464.ABSI01000012_gene2198 9.229e-69 257.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C DYD3_k127_6273608_1 1121374.KB891575_gene837 1.607e-56 209.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 DYD3_k127_6274483_4 1323663.AROI01000003_gene2336 1.62e-34 137.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Competence protein gntX GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - Pribosyltran DYD3_k127_6274483_1 472759.Nhal_0761 1.436e-99 333.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1WWA7@135613|Chromatiales 135613|Chromatiales H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD3_k127_6274483_0 1232683.ADIMK_2366 2.591e-258 813.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,46544@72275|Alteromonadaceae 1236|Gammaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge DYD3_k127_6274483_2 1396858.Q666_09445 2.203e-47 173.0 COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,4679E@72275|Alteromonadaceae 1236|Gammaproteobacteria J translation initiation inhibitor, yjgF family tdcF - - - - - - - - - - - Ribonuc_L-PSP DYD3_k127_6274483_3 935567.JAES01000006_gene329 6.439e-46 170.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1X43I@135614|Xanthomonadales 135614|Xanthomonadales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS DYD3_k127_6283005_1 1397527.Q670_01215 5.947e-60 211.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1XJD4@135619|Oceanospirillales 135619|Oceanospirillales P COG1392 Phosphate transport regulator (distant homolog of PhoU) - - - ko:K07220 - - - - ko00000 - - - PhoU_div DYD3_k127_6283005_0 1122201.AUAZ01000007_gene3678 2.665e-170 544.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,4650Z@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0306 Phosphate sulphate permeases pitA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 DYD3_k127_6283005_2 1380394.JADL01000012_gene962 5.027e-45 176.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,2JPD5@204441|Rhodospirillales 204441|Rhodospirillales V MatE norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD3_k127_6283005_3 452637.Oter_3198 1.281e-18 87.0 COG0457@1|root,COG0457@2|Bacteria,46V1N@74201|Verrucomicrobia,3KA0R@414999|Opitutae 74201|Verrucomicrobia M SMART Tetratricopeptide domain protein - - - - - - - - - - - - PMT_2,TPR_11,TPR_16,TPR_2,TPR_8 DYD3_k127_6345980_1 1122135.KB893146_gene1513 7.814e-61 226.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q ABC-type transport system involved in resistance to organic solvents permease component MA20_08115 - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS,STAS_2 DYD3_k127_6345980_0 570967.JMLV01000012_gene3208 9.128e-87 293.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2JQTF@204441|Rhodospirillales 204441|Rhodospirillales Q ATPases associated with a variety of cellular activities - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD3_k127_6345980_2 551275.KB899547_gene493 8.616e-25 117.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,43XQT@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component MA20_08125 - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD3_k127_6345980_4 441620.Mpop_0820 1.356e-09 67.0 COG3218@1|root,COG3218@2|Bacteria,1RI22@1224|Proteobacteria,2UB1D@28211|Alphaproteobacteria,1JTYP@119045|Methylobacteriaceae 28211|Alphaproteobacteria S ABC-type transport auxiliary lipoprotein component - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux DYD3_k127_6345980_5 87626.PTD2_04958 0.0002263 45.0 2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_6345980_3 682795.AciX8_1445 1.589e-24 105.0 COG0154@1|root,COG0154@2|Bacteria,3Y6E5@57723|Acidobacteria,2JKCM@204432|Acidobacteriia 204432|Acidobacteriia J PFAM Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase DYD3_k127_6368953_0 1123073.KB899241_gene2641 2.772e-138 461.0 COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1X57Y@135614|Xanthomonadales 135614|Xanthomonadales K Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - Patatin,cNMP_binding DYD3_k127_6368953_1 1121930.AQXG01000016_gene1804 2.302e-06 55.0 2DBBT@1|root,2Z8AC@2|Bacteria 2|Bacteria S Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg DYD3_k127_6374641_1 378806.STAUR_8023 8.837e-46 179.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Belongs to the 5'-nucleotidase family - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos DYD3_k127_6374641_2 714943.Mucpa_0643 1.476e-40 158.0 COG0454@1|root,COG0456@2|Bacteria,4NYPT@976|Bacteroidetes,1IUKE@117747|Sphingobacteriia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 DYD3_k127_6374641_0 1137799.GZ78_13835 1.862e-189 599.0 COG1015@1|root,COG1015@2|Bacteria,1MVN8@1224|Proteobacteria,1RQ6W@1236|Gammaproteobacteria,1XJ0H@135619|Oceanospirillales 135619|Oceanospirillales G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB - 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme DYD3_k127_6380972_1 1260251.SPISAL_00650 1.704e-25 106.0 COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1WZR6@135613|Chromatiales 135613|Chromatiales S Zinc-finger domain - - - - - - - - - - - - zf-CHCC DYD3_k127_6380972_0 187272.Mlg_2698 7.033e-229 741.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales 135613|Chromatiales OT Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE - 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE DYD3_k127_6380972_2 29581.BW37_02666 1.651e-11 66.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,475C1@75682|Oxalobacteraceae 28216|Betaproteobacteria T Putative diguanylate phosphodiesterase - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - DUF2222,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9 DYD3_k127_6381415_1 566466.NOR53_3413 8.11e-60 216.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 DYD3_k127_6381415_0 713586.KB900536_gene2809 5.62e-95 317.0 COG2085@1|root,COG2085@2|Bacteria,1RCXR@1224|Proteobacteria,1S463@1236|Gammaproteobacteria 1236|Gammaproteobacteria S NADP oxidoreductase, coenzyme f420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored DYD3_k127_6381415_2 365046.Rta_13530 1.275e-54 202.0 COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,2VV1E@28216|Betaproteobacteria 28216|Betaproteobacteria S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP DYD3_k127_6382020_1 1382359.JIAL01000001_gene2776 6.547e-60 214.0 COG3467@1|root,COG3467@2|Bacteria,3Y4HI@57723|Acidobacteria,2JMS6@204432|Acidobacteriia 204432|Acidobacteriia S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 DYD3_k127_6382020_0 1517416.IDAT_03565 1.599e-95 320.0 COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,2QFV9@267893|Idiomarinaceae 1236|Gammaproteobacteria P Sodium:sulfate symporter transmembrane region sdcS - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp DYD3_k127_6387544_0 321846.PS417_00280 2.677e-113 380.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Radical SAM - - - - - - - - - - - - Radical_SAM DYD3_k127_6390685_1 314278.NB231_13646 3.248e-93 316.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria,1WX4F@135613|Chromatiales 135613|Chromatiales P ABC-type glycine betaine transport system - - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC DYD3_k127_6390685_0 377629.TERTU_2516 8.904e-242 762.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,2PN2D@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria O Hsp90 protein htpG GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 DYD3_k127_6395233_5 395494.Galf_2510 4.382e-30 128.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,44VS4@713636|Nitrosomonadales 28216|Betaproteobacteria H Uroporphyrinogen-III synthase HemD hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 DYD3_k127_6395233_1 1122185.N792_00835 1.716e-89 307.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1X4A7@135614|Xanthomonadales 135614|Xanthomonadales H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC DYD3_k127_6395233_3 396588.Tgr7_0031 2.048e-71 254.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1WY8N@135613|Chromatiales 135613|Chromatiales KT Response regulator of the LytR AlgR family - - - ko:K08083 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg DYD3_k127_6395233_2 396588.Tgr7_0032 1.028e-77 272.0 COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1WYMY@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K08082 ko02020,map02020 M00493 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - His_kinase DYD3_k127_6395233_7 399739.Pmen_3257 3.447e-09 65.0 2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria,1YGHW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 DYD3_k127_6395233_0 1492922.GY26_18490 1.786e-189 601.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1J4I3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium Transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp DYD3_k127_6395233_4 545264.KB898746_gene903 8.682e-53 192.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1WY86@135613|Chromatiales 135613|Chromatiales K Belongs to the P(II) protein family - - - ko:K04752 - - - - ko00000 - - - P-II DYD3_k127_6395233_6 204773.HEAR0794 2.271e-16 83.0 COG4389@1|root,COG4389@2|Bacteria,1MWEH@1224|Proteobacteria,2VIZV@28216|Betaproteobacteria,473GK@75682|Oxalobacteraceae 28216|Betaproteobacteria L Site-specific recombinase - - - - - - - - - - - - SpecificRecomb DYD3_k127_6397372_0 570952.ATVH01000013_gene2857 4.763e-247 767.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,2JPS3@204441|Rhodospirillales 204441|Rhodospirillales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD3_k127_6397372_1 1134474.O59_004072 1.37e-29 129.0 COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1T0B8@1236|Gammaproteobacteria 1236|Gammaproteobacteria T conserved protein, contains FHA domain - - - ko:K11894,ko:K11913 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko02044 3.A.23.1 - - FHA DYD3_k127_639830_8 1089551.KE386572_gene2252 9.672e-64 229.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TTXX@28211|Alphaproteobacteria 28211|Alphaproteobacteria ET ABC-type amino acid transport signal transduction systems periplasmic component domain - - - ko:K02030,ko:K10001 ko02010,ko02020,map02010,map02020 M00230,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 - - SBP_bac_3 DYD3_k127_639830_11 1304883.KI912532_gene2345 2.232e-35 140.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2VSDN@28216|Betaproteobacteria,2KWKP@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function, DUF - - - - - - - - - - - - DUF411 DYD3_k127_639830_1 349102.Rsph17025_0780 4.902e-150 483.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,1FD4F@1060|Rhodobacter 28211|Alphaproteobacteria E Cys/Met metabolism PLP-dependent enzyme metB - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP DYD3_k127_639830_9 396588.Tgr7_0189 3.033e-60 218.0 COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria 1236|Gammaproteobacteria D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA DYD3_k127_639830_5 314285.KT71_11585 2.349e-89 306.0 COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,1J5Q0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S EamA-like transporter family - - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA DYD3_k127_639830_6 1123400.KB904763_gene2429 2.518e-88 301.0 COG2503@1|root,COG2503@2|Bacteria,1RB4N@1224|Proteobacteria,1RY2I@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Acid phosphatase hel GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - - - - - - - - - - Acid_phosphat_B DYD3_k127_639830_10 1437882.AZRU01000106_gene6586 3.172e-55 198.0 COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,1S6J5@1236|Gammaproteobacteria,1YGB9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF1993) - - - ko:K09983 - - - - ko00000 - - - DUF1993 DYD3_k127_639830_7 1380391.JIAS01000011_gene4670 2.94e-84 285.0 COG3791@1|root,COG3791@2|Bacteria,1MX4A@1224|Proteobacteria,2TSAN@28211|Alphaproteobacteria,2JV7J@204441|Rhodospirillales 204441|Rhodospirillales S Glutathione-dependent formaldehyde-activating enzyme - - 4.4.1.22 ko:K03396 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R06982 RC00069,RC01707 ko00000,ko00001,ko01000 - - - GFA DYD3_k127_639830_2 1384056.N787_03540 2.715e-143 473.0 COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,1X5X9@135614|Xanthomonadales 135614|Xanthomonadales S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 DYD3_k127_639830_3 768671.ThimaDRAFT_1458 1.519e-129 436.0 COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,1RXGJ@1236|Gammaproteobacteria,1WX7E@135613|Chromatiales 135613|Chromatiales S von Willebrand factor, type A - - 2.7.11.1 ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - VWA_2 DYD3_k127_639830_12 1116472.MGMO_26c00040 2.127e-30 127.0 2CFV2@1|root,32UMX@2|Bacteria,1N3YD@1224|Proteobacteria,1SABG@1236|Gammaproteobacteria,1XGFX@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - DYD3_k127_639830_13 1116472.MGMO_26c00030 4.047e-29 126.0 COG1842@1|root,COG1842@2|Bacteria 2|Bacteria KT Phage shock protein A - - - ko:K03615,ko:K03969,ko:K09749,ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,PspA_IM30 DYD3_k127_639830_4 1116472.MGMO_26c00020 5.585e-96 319.0 COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RRT6@1236|Gammaproteobacteria,1XFBD@135618|Methylococcales 135618|Methylococcales K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C DYD3_k127_639830_0 686340.Metal_1984 5.859e-182 592.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T23Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA DYD3_k127_639830_15 1397284.AYMN01000010_gene2953 3.388e-07 51.0 COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,1RNWZ@1236|Gammaproteobacteria,3ZZW3@613|Serratia 1236|Gammaproteobacteria O Belongs to the GST superfamily gstA - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_3,GST_N,GST_N_3 DYD3_k127_6402626_3 565045.NOR51B_571 3.726e-71 246.0 COG1574@1|root,COG1574@2|Bacteria,1MXST@1224|Proteobacteria,1RS60@1236|Gammaproteobacteria,1J7XW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 DYD3_k127_6402626_4 983545.Glaag_0580 6.13e-10 66.0 2DSYW@1|root,33HZI@2|Bacteria,1NKP8@1224|Proteobacteria,1SISV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_6402626_1 357808.RoseRS_2742 3.434e-134 442.0 COG2957@1|root,COG2957@2|Bacteria,2GAHD@200795|Chloroflexi,37657@32061|Chloroflexia 32061|Chloroflexia E Belongs to the agmatine deiminase family - - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph DYD3_k127_6402626_0 926550.CLDAP_14210 6.053e-166 532.0 COG1899@1|root,COG1899@2|Bacteria,2G7R7@200795|Chloroflexi 200795|Chloroflexi O PFAM deoxyhypusine synthase - - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS DYD3_k127_6402626_2 518766.Rmar_1413 9.223e-116 384.0 COG1166@1|root,COG1166@2|Bacteria,4PKX0@976|Bacteroidetes 976|Bacteroidetes H Catalyzes the biosynthesis of agmatine from arginine speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N DYD3_k127_6403087_3 338969.Rfer_1928 2.518e-05 55.0 COG0745@1|root,COG2197@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria,COG3829@2|Bacteria,1NWAF@1224|Proteobacteria,2WHI9@28216|Betaproteobacteria,4AGMP@80864|Comamonadaceae 28216|Betaproteobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GGDEF,GerE,PAS,PAS_3,PAS_9,Response_reg DYD3_k127_6403087_0 1196835.A458_21190 2.061e-36 144.0 COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,1Z2WU@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg DYD3_k127_6403087_1 1196835.A458_21195 4.794e-24 115.0 2A110@1|root,30P6F@2|Bacteria,1QDEK@1224|Proteobacteria,1T9D4@1236|Gammaproteobacteria,1Z2JF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_14,TPR_16,TPR_19 DYD3_k127_6403087_2 335541.Swol_2440 4.3e-11 71.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - - - - - - - - - - - HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact DYD3_k127_6404260_0 1260251.SPISAL_05885 1.108e-255 811.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales 135613|Chromatiales P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N DYD3_k127_6404260_2 1123377.AUIV01000015_gene197 4.227e-119 393.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1X4BE@135614|Xanthomonadales 135614|Xanthomonadales O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK DYD3_k127_6404260_3 1260251.SPISAL_07670 2.755e-112 379.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1WX4H@135613|Chromatiales 135613|Chromatiales M PFAM peptidase - - - - - - - - - - - - OapA,Peptidase_M23 DYD3_k127_6404260_1 765912.Thimo_1034 2.65e-162 517.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1WX6G@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b DYD3_k127_6427485_2 768671.ThimaDRAFT_1020 9.157e-28 118.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M DYD3_k127_6427485_0 105559.Nwat_0224 7.497e-159 508.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1WWBT@135613|Chromatiales 135613|Chromatiales M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 DYD3_k127_6427485_1 396588.Tgr7_0765 1.591e-115 386.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1WWTC@135613|Chromatiales 135613|Chromatiales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD3_k127_6441778_0 323850.Shew_3211 9.82e-75 257.0 COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,1S13N@1236|Gammaproteobacteria,2QB3U@267890|Shewanellaceae 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain gst5 - 2.5.1.18 ko:K00799,ko:K11209 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 DYD3_k127_6441778_1 1215092.PA6_016_01500 2.101e-52 191.0 COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,1S4K8@1236|Gammaproteobacteria,1YD9Q@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria Q DSBA-like thioredoxin domain - - 5.99.1.4 ko:K14584 ko00626,ko01100,ko01120,ko01220,map00626,map01100,map01120,map01220 M00534 R05137 RC03084 br01602,ko00000,ko00001,ko00002,ko01000 - - - DSBA DYD3_k127_6441778_2 396588.Tgr7_0447 5.351e-29 121.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1WWU1@135613|Chromatiales 135613|Chromatiales S TamB, inner membrane protein subunit of TAM complex - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB DYD3_k127_6450522_2 1195246.AGRI_06690 1.986e-11 69.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4647F@72275|Alteromonadaceae 1236|Gammaproteobacteria O Molecular chaperone. Has ATPase activity htpG GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 DYD3_k127_6450522_0 697282.Mettu_3282 4.793e-192 610.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1XEVC@135618|Methylococcales 135618|Methylococcales S Domain of unknown function (DUF4478) - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox DYD3_k127_6450522_1 765912.Thimo_0385 1.1e-41 164.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1TAE6@1236|Gammaproteobacteria,1WYSH@135613|Chromatiales 135613|Chromatiales S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD DYD3_k127_6450800_6 1127673.GLIP_2003 6.426e-22 97.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,465M6@72275|Alteromonadaceae 1236|Gammaproteobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD3_k127_6450800_2 1120953.AUBH01000001_gene914 1.126e-142 467.0 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,46698@72275|Alteromonadaceae 1236|Gammaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD3_k127_6450800_3 314287.GB2207_06543 9.672e-64 229.0 28NHW@1|root,2ZBJG@2|Bacteria,1RBJB@1224|Proteobacteria,1S31B@1236|Gammaproteobacteria,1J9WS@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_6450800_1 663321.REG_0174 1.309e-147 479.0 COG3177@1|root,COG3177@2|Bacteria,1PMMK@1224|Proteobacteria,1T9TH@1236|Gammaproteobacteria,283MQ@191675|unclassified Enterobacteriaceae 1236|Gammaproteobacteria S Fic/DOC family - - - - - - - - - - - - Fic DYD3_k127_6450800_0 1121937.AUHJ01000003_gene3204 5.133e-194 614.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,465BJ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 DYD3_k127_6450800_7 331869.BAL199_03289 1.881e-20 99.0 COG3741@1|root,COG3741@2|Bacteria,1NBYI@1224|Proteobacteria 1224|Proteobacteria E N-formylglutamate amidohydrolase - - - - - - - - - - - - - DYD3_k127_6450800_5 861299.J421_1228 4.677e-22 104.0 2E9H4@1|root,333Q5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_6450800_4 1280944.HY17_18360 1.769e-46 189.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C DYD3_k127_6452017_2 1484158.PSNIH1_08685 7.064e-119 389.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,3VYCC@53335|Pantoea 1236|Gammaproteobacteria E Belongs to the transferase hexapeptide repeat family dapD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iSbBS512_1146.SbBS512_E0158 Hexapep,Hexapep_2,THDPS_N_2 DYD3_k127_6452017_0 223283.PSPTO_1532 2.255e-260 829.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1Z4WR@136849|Pseudomonas syringae group 1236|Gammaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 DYD3_k127_6452017_1 713586.KB900536_gene142 9.263e-128 413.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1WX9V@135613|Chromatiales 135613|Chromatiales E TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 DYD3_k127_6452017_4 1123073.KB899241_gene3377 3.34e-104 351.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1X2XU@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 DYD3_k127_6452017_3 1158150.KB906242_gene137 2.418e-111 367.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales 135613|Chromatiales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS DYD3_k127_6452017_5 713586.KB900536_gene139 2.467e-102 338.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1WX9S@135613|Chromatiales 135613|Chromatiales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD3_k127_6452017_6 1049564.TevJSym_ba00160 3.787e-77 262.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1J5ZJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF DYD3_k127_6452017_7 187272.Mlg_1859 1.631e-58 208.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1WX0N@135613|Chromatiales 135613|Chromatiales I Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf DYD3_k127_6452725_3 398525.KB900701_gene2396 6.486e-20 91.0 2919Q@1|root,32TZW@2|Bacteria,1R3DM@1224|Proteobacteria,2U015@28211|Alphaproteobacteria,3K71Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_6452725_0 1267533.KB906733_gene3563 3.001e-105 365.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C DYD3_k127_6452725_1 1030157.AFMP01000031_gene3007 7.096e-82 299.0 COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3JH@28211|Alphaproteobacteria,2K1GK@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_6452725_2 67352.JODS01000001_gene476 5.175e-28 132.0 COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria 201174|Actinobacteria Q Domain of unknown function (DUF5122) beta-propeller - - - - - - - - - - - - DUF11,DUF5122,HemolysinCabind DYD3_k127_6461943_0 42565.FP66_11430 3.283e-222 699.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria,1XICM@135619|Oceanospirillales 135619|Oceanospirillales V (ABC) transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran DYD3_k127_6465968_1 379066.GAU_2742 3.104e-181 576.0 COG0433@1|root,COG0433@2|Bacteria,1ZUJE@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Domain of unknown function DUF87 - - - - - - - - - - - - DUF87 DYD3_k127_6465968_0 1278073.MYSTI_04371 1.959e-225 713.0 COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,437WG@68525|delta/epsilon subdivisions,2X364@28221|Deltaproteobacteria,2YUG4@29|Myxococcales 28221|Deltaproteobacteria E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 DYD3_k127_6465968_3 765914.ThisiDRAFT_0559 3.855e-87 295.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales 135613|Chromatiales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC DYD3_k127_6465968_6 236097.ADG881_797 3.189e-08 60.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1XM56@135619|Oceanospirillales 135619|Oceanospirillales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB - - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD3_k127_6465968_5 765910.MARPU_00350 8.587e-12 68.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1WZ7B@135613|Chromatiales 135613|Chromatiales U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 DYD3_k127_6465968_4 1384054.N790_05025 2.063e-54 194.0 COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1X6FE@135614|Xanthomonadales 135614|Xanthomonadales J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase DYD3_k127_6465968_2 1384056.N787_02550 3.756e-133 434.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1X5K5@135614|Xanthomonadales 135614|Xanthomonadales Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP DYD3_k127_6474790_0 472759.Nhal_1524 4.526e-71 249.0 COG0741@1|root,COG0741@2|Bacteria,1RFDI@1224|Proteobacteria,1S52B@1236|Gammaproteobacteria,1WYB9@135613|Chromatiales 135613|Chromatiales M PFAM Lytic - - - - - - - - - - - - SLT DYD3_k127_6474790_3 177439.DP1217 1.605e-38 165.0 2CGG1@1|root,339F6@2|Bacteria,1NA7Y@1224|Proteobacteria,432XB@68525|delta/epsilon subdivisions,2WXKP@28221|Deltaproteobacteria,2MP7P@213118|Desulfobacterales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_6474790_4 1049564.TevJSym_ac00360 1.04e-13 82.0 COG4942@1|root,COG4942@2|Bacteria,1NNFC@1224|Proteobacteria 1224|Proteobacteria D peptidase - - - - - - - - - - - - - DYD3_k127_6474790_1 1049564.TevJSym_ac00350 6.058e-47 176.0 2EBH3@1|root,335HM@2|Bacteria,1NDXE@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_6474790_2 1049564.TevJSym_ac00340 1.857e-39 149.0 2ER3M@1|root,33IP8@2|Bacteria,1NGAV@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_6484502_9 1123401.JHYQ01000005_gene306 8.014e-27 113.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,4602R@72273|Thiotrichales 72273|Thiotrichales C NADH-quinone oxidoreductase, chain M - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M DYD3_k127_6484502_0 187272.Mlg_1959 3.868e-284 885.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales 135613|Chromatiales CP NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N DYD3_k127_6484502_8 519989.ECTPHS_07087 5.514e-42 156.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,1S6FN@1236|Gammaproteobacteria,1WYHG@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 DYD3_k127_6484502_7 1469245.JFBG01000086_gene1619 5.088e-60 214.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria,1WXHS@135613|Chromatiales 135613|Chromatiales C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 DYD3_k127_6484502_5 1026882.MAMP_00779 1.103e-74 254.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,460DI@72273|Thiotrichales 72273|Thiotrichales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 DYD3_k127_6484502_4 713587.THITH_12955 7.093e-149 481.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1WXDH@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh DYD3_k127_6484502_1 396588.Tgr7_0992 1.162e-236 757.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, chain G - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 DYD3_k127_6484502_3 396588.Tgr7_0991 4.436e-208 656.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1WWH3@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB DYD3_k127_6484502_6 519989.ECTPHS_07057 5.189e-71 243.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales 135613|Chromatiales C TIGRFAM NADH-quinone oxidoreductase, E subunit - - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx DYD3_k127_6484502_2 713586.KB900536_gene3046 3.027e-222 691.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa DYD3_k127_6496748_4 644107.SL1157_0788 1.915e-47 181.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,4NB3E@97050|Ruegeria 28211|Alphaproteobacteria P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N DYD3_k127_6496748_2 1304275.C41B8_09181 3.685e-113 376.0 COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S succinylglutamate desuccinylase aspartoacylase - - - ko:K06987 - - - - ko00000 - - - AstE_AspA DYD3_k127_6496748_3 1117318.PRUB_13796 1.228e-49 188.0 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,2Q2GU@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria O protein conserved in archaea - - - - - - - - - - - - Zn_protease DYD3_k127_6496748_0 572477.Alvin_1979 9.834e-149 478.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1WX7Z@135613|Chromatiales 135613|Chromatiales HJ Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK DYD3_k127_6496748_6 411154.GFO_0980 4.279e-24 111.0 COG1917@1|root,COG1917@2|Bacteria,4P2XE@976|Bacteroidetes,1IAY3@117743|Flavobacteriia 976|Bacteroidetes S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - DYD3_k127_6496748_7 1121931.AUHG01000012_gene2925 4.279e-24 111.0 COG1917@1|root,COG1917@2|Bacteria,4P2XE@976|Bacteroidetes,1IAY3@117743|Flavobacteriia 976|Bacteroidetes S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - DYD3_k127_6496748_1 1122134.KB893650_gene196 6.108e-142 471.0 COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1XHSW@135619|Oceanospirillales 135619|Oceanospirillales P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,TrkA_C DYD3_k127_6496748_5 1122194.AUHU01000001_gene52 1.28e-40 156.0 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,4640D@72275|Alteromonadaceae 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT DYD3_k127_6507492_12 1089447.RHAA1_00546 5.073e-13 72.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1Y7WM@135625|Pasteurellales 135625|Pasteurellales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS DYD3_k127_6507492_8 396588.Tgr7_0826 6.9e-53 193.0 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1WWJB@135613|Chromatiales 135613|Chromatiales E PFAM Amino acid-binding ACT - - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 DYD3_k127_6507492_6 1415754.JQMK01000002_gene3572 3.553e-65 226.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,46AS0@72275|Alteromonadaceae 1236|Gammaproteobacteria O Redoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD3_k127_6507492_4 472759.Nhal_3508 2.457e-89 313.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales 135613|Chromatiales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - - - - - - - - - - Peptidase_M48,TPR_19 DYD3_k127_6507492_7 519989.ECTPHS_11442 3.101e-58 211.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1WW1D@135613|Chromatiales 135613|Chromatiales M PFAM VacJ family lipoprotein - - - ko:K04754 - - - - ko00000 - - - MlaA DYD3_k127_6507492_13 1283300.ATXB01000001_gene733 1.555e-09 66.0 COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1XFQI@135618|Methylococcales 135618|Methylococcales S STAS domain - - - ko:K07122 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - STAS_2 DYD3_k127_6507492_10 666685.R2APBS1_3356 1.174e-42 164.0 COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1X73J@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents auxiliary component - - - ko:K07323 ko02010,map02010 M00210 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27.3 - - MlaC DYD3_k127_6507492_9 1158756.AQXQ01000006_gene53 9.073e-44 164.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1WXYG@135613|Chromatiales 135613|Chromatiales Q PFAM Mammalian cell entry related domain protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD DYD3_k127_6507492_5 395493.BegalDRAFT_1604 1.303e-77 267.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,460AA@72273|Thiotrichales 72273|Thiotrichales Q ABC transporter permease - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE DYD3_k127_6507492_2 713586.KB900536_gene1408 2.88e-100 341.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1WW98@135613|Chromatiales 135613|Chromatiales Q PFAM ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran DYD3_k127_6507492_1 1411123.JQNH01000001_gene2532 3.074e-126 417.0 COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TSIV@28211|Alphaproteobacteria 28211|Alphaproteobacteria G fructose-bisphosphate aldolase fbaB - 4.1.2.13 ko:K01623 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147 - - - Glycolytic DYD3_k127_6507492_11 1163408.UU9_16301 1.913e-34 137.0 COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X6CG@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional regulator - - - - - - - - - - - - Rrf2 DYD3_k127_6507492_0 472759.Nhal_0688 1.129e-275 852.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1WWT1@135613|Chromatiales 135613|Chromatiales O TIGRFAM FeS assembly protein SufB - - - ko:K09014 - - - - ko00000 - - - UPF0051 DYD3_k127_6507492_3 748280.NH8B_2180 6.834e-99 327.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2VNGT@28216|Betaproteobacteria 28216|Betaproteobacteria O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran DYD3_k127_6516623_3 314285.KT71_05992 1.587e-67 236.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J80V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD3_k127_6516623_1 314285.KT71_05997 1.016e-181 578.0 COG0845@1|root,COG0845@2|Bacteria,1NGI2@1224|Proteobacteria,1RPPI@1236|Gammaproteobacteria,1J744@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 DYD3_k127_6516623_2 1234595.C725_1358 1.528e-92 309.0 COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,4BQ2M@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria V ATPases associated with a variety of cellular activities - - - ko:K02003,ko:K05685 ko02010,map02010 M00258,M00709 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.122.1,3.A.1.122.12 - - ABC_tran,FtsX,MacB_PCD DYD3_k127_6516623_0 314285.KT71_06007 4.863e-244 766.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,1RVN1@1236|Gammaproteobacteria,1J78V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V COG0577 ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD DYD3_k127_6560019_4 247639.MGP2080_00965 5.972e-13 70.0 COG1764@1|root,COG1764@2|Bacteria,1RJIP@1224|Proteobacteria,1S6QM@1236|Gammaproteobacteria,1J9ZC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O redox protein, regulator of disulfide bond formation - - - - - - - - - - - - OsmC DYD3_k127_6560019_0 745411.B3C1_16004 7.056e-180 580.0 COG4805@1|root,COG4805@2|Bacteria,1PIM6@1224|Proteobacteria,1RRW7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD3_k127_6560019_3 292415.Tbd_0063 1.203e-18 90.0 2EH48@1|root,338P5@2|Bacteria,1NFS9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_6560019_1 247633.GP2143_16886 9.283e-98 332.0 COG1028@1|root,COG1028@2|Bacteria,1REA0@1224|Proteobacteria,1SMHH@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short DYD3_k127_6560019_2 243365.CV_3507 1.307e-65 229.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,2KQ1A@206351|Neisseriales 206351|Neisseriales F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC DYD3_k127_6562720_3 1123368.AUIS01000006_gene607 4.28e-22 104.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,2NC2K@225057|Acidithiobacillales 225057|Acidithiobacillales H Mur ligase middle domain - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M DYD3_k127_6562720_4 1415754.JQMK01000002_gene3687 1.063e-11 74.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,468K7@72275|Alteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria dedD - - ko:K03749 - - - - ko00000 - - - SPOR DYD3_k127_6562720_2 1298593.TOL_1541 3.095e-25 111.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1XKNI@135619|Oceanospirillales 135619|Oceanospirillales S colicin V production cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V DYD3_k127_6562720_0 523791.Kkor_1480 2.797e-220 694.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XHAH@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,Pribosyltran DYD3_k127_6562720_1 614083.AWQR01000001_gene3031 7.951e-65 237.0 COG0515@1|root,COG0745@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria 28216|Betaproteobacteria KLT serine threonine protein kinase - - 2.7.11.1 ko:K11912,ko:K12132 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - HAMP,Pkinase DYD3_k127_6581904_1 357804.Ping_1553 3.464e-61 217.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria 1236|Gammaproteobacteria U UPF0056 membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC DYD3_k127_6581904_0 1110502.TMO_1614 1.905e-84 295.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,2TSKB@28211|Alphaproteobacteria,2JQY4@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the Orn Lys Arg decarboxylase class-II family - - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC DYD3_k127_6581904_3 1121930.AQXG01000001_gene1371 1.207e-44 164.0 COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes 976|Bacteroidetes J tRNA-binding protein csaA - - ko:K06878 - - - - ko00000 - - - tRNA_bind DYD3_k127_6581904_2 1279017.AQYJ01000021_gene2813 9.841e-55 199.0 COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,1S4EM@1236|Gammaproteobacteria 1236|Gammaproteobacteria O redox protein regulator of disulfide bond formation - - - - - - - - - - - - OsmC DYD3_k127_6581904_6 491952.Mar181_1549 3.863e-07 57.0 2E66C@1|root,330V0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_6581904_4 1185876.BN8_03494 1.442e-38 147.0 COG3324@1|root,COG3324@2|Bacteria,4NR6W@976|Bacteroidetes,47RGH@768503|Cytophagia 976|Bacteroidetes S glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase DYD3_k127_6581904_5 351627.Csac_1201 1.066e-22 100.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,42FSE@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase DYD3_k127_6586044_2 278963.ATWD01000001_gene2876 4.337e-09 66.0 COG1413@1|root,COG1413@2|Bacteria,3Y7PB@57723|Acidobacteria 57723|Acidobacteria C HEAT repeats - - - - - - - - - - - - HEAT_2 DYD3_k127_6586044_3 861299.J421_0306 2.867e-06 58.0 COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes 142182|Gemmatimonadetes C HEAT repeats - - - - - - - - - - - - HEAT_2 DYD3_k127_6586044_0 565045.NOR51B_571 1.832e-242 766.0 COG1574@1|root,COG1574@2|Bacteria,1MXST@1224|Proteobacteria,1RS60@1236|Gammaproteobacteria,1J7XW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 DYD3_k127_6586044_1 886293.Sinac_3541 1.395e-15 78.0 COG2957@1|root,COG2957@2|Bacteria,2IXRY@203682|Planctomycetes 203682|Planctomycetes E Belongs to the agmatine deiminase family aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph DYD3_k127_6586256_4 32042.PstZobell_16471 1.184e-20 104.0 COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1Z0S7@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S family transcriptional regulator rodZ GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 DYD3_k127_6586256_3 1500893.JQNB01000001_gene2768 2.363e-38 154.0 COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1X5IM@135614|Xanthomonadales 135614|Xanthomonadales NU type IV pilus biogenesis stability protein PilW pilF - - ko:K02656 - - - - ko00000,ko02035,ko02044 - - - TPR_10,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8 DYD3_k127_6586256_0 472759.Nhal_1092 1.081e-131 436.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales 135613|Chromatiales J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM DYD3_k127_6586256_1 1279019.ARQK01000036_gene1616 6.998e-66 228.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1WYAE@135613|Chromatiales 135613|Chromatiales F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK DYD3_k127_6586256_2 471881.PROPEN_01913 9.689e-40 154.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,1S5XD@1236|Gammaproteobacteria,3Z2QS@583|Proteus 1236|Gammaproteobacteria C iron-sulfur cluster assembly protein iscA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 - ko:K05997,ko:K13628 - - - - ko00000,ko03016 - - iAPECO1_1312.APECO1_3997,iB21_1397.B21_02384,iBWG_1329.BWG_2292,iE2348C_1286.E2348C_2811,iEC042_1314.EC042_2732,iEC55989_1330.EC55989_2813,iECABU_c1320.ECABU_c28340,iECBD_1354.ECBD_1156,iECB_1328.ECB_02420,iECDH10B_1368.ECDH10B_2695,iECD_1391.ECD_02420,iECED1_1282.ECED1_2959,iECIAI1_1343.ECIAI1_2580,iECIAI39_1322.ECIAI39_2729,iECNA114_1301.ECNA114_2607,iECO103_1326.ECO103_3045,iECO111_1330.ECO111_3252,iECO26_1355.ECO26_3575,iECOK1_1307.ECOK1_2877,iECP_1309.ECP_2533,iECS88_1305.ECS88_2704,iECSE_1348.ECSE_2814,iECSF_1327.ECSF_2372,iECSP_1301.ECSP_3472,iECUMN_1333.ECUMN_2848,iECW_1372.ECW_m2754,iECs_1301.ECs3394,iEKO11_1354.EKO11_1205,iETEC_1333.ETEC_2685,iEcDH1_1363.EcDH1_1140,iEcSMS35_1347.EcSMS35_2681,iEcolC_1368.EcolC_1149,iG2583_1286.G2583_3058,iJO1366.b2528,iLF82_1304.LF82_1120,iNRG857_1313.NRG857_12580,iSBO_1134.SBO_2552,iSDY_1059.SDY_2724,iSF_1195.SF2575,iSSON_1240.SSON_2610,iS_1188.S2747,iUMN146_1321.UM146_04060,iUMNK88_1353.UMNK88_3181,iWFL_1372.ECW_m2754,iY75_1357.Y75_RS13195,iZ_1308.Z3795,ic_1306.c3053 Fe-S_biosyn DYD3_k127_6586256_5 5825.PCHAS_132150 3.223e-05 51.0 COG0822@1|root,KOG3361@2759|Eukaryota,3YA95@5794|Apicomplexa,3KAW6@422676|Aconoidasida,3YZKD@5819|Haemosporida 422676|Aconoidasida C Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic 2Fe-2S and 4Fe-4S proteins - GO:0003674,GO:0003824,GO:0005198,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0031974,GO:0032947,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K22068 - - - - ko00000,ko03029 - - - NifU_N,RNase_P_Rpp14 DYD3_k127_6624260_0 1265313.HRUBRA_01443 6.522e-256 800.0 COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1J7GA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Acetyl-coenzyme A synthetase N-terminus acsA - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C DYD3_k127_6624260_2 1121033.AUCF01000032_gene2611 7.164e-36 142.0 COG0824@1|root,COG0824@2|Bacteria,1MZB3@1224|Proteobacteria,2U7CU@28211|Alphaproteobacteria,2JTMB@204441|Rhodospirillales 204441|Rhodospirillales S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT_2 DYD3_k127_6624260_1 83406.HDN1F_32240 8.17e-204 647.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1JBW8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N DYD3_k127_6624260_3 909943.HIMB100_00008490 5.002e-11 63.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2TSRR@28211|Alphaproteobacteria,4BP9E@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus DYD3_k127_6645209_1 313606.M23134_02374 4.12e-98 327.0 COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,47K7T@768503|Cytophagia 976|Bacteroidetes M mandelate racemase muconate lactonizing - - 4.2.1.113,5.1.1.20,5.1.1.3 ko:K01776,ko:K02549,ko:K19802 ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110 M00116 R00260,R04031,R10938 RC00302,RC01053,RC03309 ko00000,ko00001,ko00002,ko01000,ko01011 - - - MR_MLE_C,MR_MLE_N DYD3_k127_6645209_0 861299.J421_6093 2.874e-129 423.0 COG2355@1|root,COG2355@2|Bacteria,1ZU9D@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 DYD3_k127_6645209_2 1122137.AQXF01000004_gene1588 2.318e-15 80.0 COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,2U2RD@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase DYD3_k127_6653628_4 1385515.N791_12340 6.473e-19 88.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,1X3ZJ@135614|Xanthomonadales 135614|Xanthomonadales E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth DYD3_k127_6653628_1 471881.PROPEN_04713 1.026e-102 340.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,3Z2EF@583|Proteus 1236|Gammaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - ko:K01663,ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iYL1228.KPN_02481 His_biosynth DYD3_k127_6653628_3 529507.PMI0658 1.331e-23 103.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,3Z24F@583|Proteus 1236|Gammaproteobacteria E Phosphoribosyl-AMP cyclohydrolase hisI GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186 PRA-CH,PRA-PH DYD3_k127_6653628_0 518766.Rmar_1656 8.64e-290 915.0 COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Belongs to the Orn Lys Arg decarboxylase class-II family - - 2.7.2.4,4.1.1.20 ko:K00928,ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC DYD3_k127_6653628_2 1488328.JMCL01000060_gene3632 7.824e-99 327.0 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD DYD3_k127_6659480_1 365046.Rta_01570 1.125e-24 111.0 COG3279@1|root,COG3279@2|Bacteria,1R90R@1224|Proteobacteria,2VPHS@28216|Betaproteobacteria,4ABN0@80864|Comamonadaceae 28216|Betaproteobacteria KT LytTr DNA-binding domain - - - - - - - - - - - - LytTR DYD3_k127_6659480_0 314285.KT71_06242 2.38e-119 402.0 COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1J5SG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG1629 Outer membrane receptor proteins, mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_666328_3 1073999.BN137_1590 9.529e-93 311.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria 1236|Gammaproteobacteria I malonyl CoA-acyl carrier protein transacylase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 DYD3_k127_666328_2 1442599.JAAN01000031_gene1439 7.402e-93 310.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1X475@135614|Xanthomonadales 135614|Xanthomonadales IQ Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 DYD3_k127_666328_6 243924.LT42_09470 6.889e-32 125.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding DYD3_k127_666328_0 1123401.JHYQ01000031_gene3404 2.04e-179 571.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales 72273|Thiotrichales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt DYD3_k127_666328_1 396588.Tgr7_1832 3.336e-142 466.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales 135613|Chromatiales EH Anthranilate synthase component I - - 2.6.1.85,4.1.3.27 ko:K01657,ko:K01665 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind DYD3_k127_666328_5 1452718.JBOY01000096_gene2958 2.257e-58 213.0 COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH 4-amino-4-deoxychorismate lyase pabC GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366 Aminotran_4 DYD3_k127_666328_4 644801.Psest_1692 3.176e-89 307.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1Z2CS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - ko:K07082 - - - - ko00000 - - - YceG DYD3_k127_666328_7 1121921.KB898711_gene2096 1.483e-18 88.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,2PNC8@256005|Alteromonadales genera incertae sedis 1236|Gammaproteobacteria F Thymidylate kinase tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c13120,ic_1306.c1370 Thymidylate_kin DYD3_k127_668132_1 1379270.AUXF01000001_gene2022 2.875e-13 71.0 COG4877@1|root,COG4877@2|Bacteria,1ZVAE@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - DYD3_k127_668132_0 745411.B3C1_13254 2.501e-100 334.0 COG0330@1|root,COG0330@2|Bacteria,1P8ZI@1224|Proteobacteria,1RUQU@1236|Gammaproteobacteria,1J7WG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - - - - - - - - - - Band_7 DYD3_k127_668132_2 1300345.LF41_2525 5.463e-06 53.0 COG4319@1|root,COG4319@2|Bacteria,1N361@1224|Proteobacteria,1S9P8@1236|Gammaproteobacteria,1X7TS@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440,SnoaL_2,SnoaL_3 DYD3_k127_6684843_2 498211.CJA_0482 2.173e-25 108.0 COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,1RQHT@1236|Gammaproteobacteria,1FFRH@10|Cellvibrio 1236|Gammaproteobacteria P Protein of unknown function DUF47 UF78_21250 - - ko:K07220 - - - - ko00000 - - - PhoU_div DYD3_k127_6684843_1 1123073.KB899241_gene2772 1.429e-53 192.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1X5XQ@135614|Xanthomonadales 135614|Xanthomonadales S EVE domain-containing protein - - - - - - - - - - - - EVE DYD3_k127_6684843_0 566466.NOR53_3173 1.215e-70 251.0 COG2267@1|root,COG2267@2|Bacteria,1QVW4@1224|Proteobacteria,1T2Y5@1236|Gammaproteobacteria,1J9P7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Esterase,Hydrolase_4 DYD3_k127_6686771_1 13690.CP98_03996 4.742e-67 241.0 COG3746@1|root,COG3746@2|Bacteria 2|Bacteria - - - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P DYD3_k127_6686771_0 762376.AXYL_01565 4.251e-77 272.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria,3T7GG@506|Alcaligenaceae 28216|Betaproteobacteria S Aldo keto reductases, related to diketogulonate reductase - - - - - - - - - - - - Aldo_ket_red DYD3_k127_6686771_2 1353528.DT23_07450 1.277e-15 81.0 COG1807@1|root,COG1807@2|Bacteria,1PKMZ@1224|Proteobacteria,2V6GX@28211|Alphaproteobacteria,2XKPQ@285107|Thioclava 28211|Alphaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 DYD3_k127_6686973_2 1242864.D187_002372 1.391e-25 111.0 COG4143@1|root,COG4143@2|Bacteria,1R4IE@1224|Proteobacteria,42QHK@68525|delta/epsilon subdivisions,2WUK2@28221|Deltaproteobacteria 28221|Deltaproteobacteria H (ABC) transporter - - - - - - - - - - - - - DYD3_k127_6686973_0 1144319.PMI16_01603 3.548e-128 423.0 COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2VGZS@28216|Betaproteobacteria,472Q9@75682|Oxalobacteraceae 28216|Betaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase trxB2 - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_3 DYD3_k127_6686973_3 383372.Rcas_2852 1.002e-24 117.0 COG0010@1|root,COG0010@2|Bacteria,2G8DY@200795|Chloroflexi 200795|Chloroflexi E Belongs to the arginase family - - 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase DYD3_k127_6686973_1 195250.CM001776_gene1121 3.087e-65 231.0 COG0491@1|root,COG0491@2|Bacteria,1G400@1117|Cyanobacteria,1H175@1129|Synechococcus 1117|Cyanobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD3_k127_668845_1 566466.NOR53_3084 4.788e-21 100.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RPAA@1236|Gammaproteobacteria,1J6UF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_8 DYD3_k127_668845_0 314285.KT71_05992 1.865e-175 561.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J80V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Sigma-54 interaction domain - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat DYD3_k127_6695534_0 1163407.UU7_14885 0.0 1478.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales 135614|Xanthomonadales V Efflux pump membrane transporter - - - ko:K18299 - M00641 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2.16 - - ACR_tran DYD3_k127_6695534_1 1198452.Jab_1c21890 4.07e-41 159.0 COG3134@1|root,COG3134@2|Bacteria,1N0SK@1224|Proteobacteria,2WIIM@28216|Betaproteobacteria,474FG@75682|Oxalobacteraceae 28216|Betaproteobacteria S Glycine zipper 2TM domain - - - - - - - - - - - - Rick_17kDa_Anti DYD3_k127_6695534_2 522306.CAP2UW1_1082 5.184e-29 117.0 COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,1KQ41@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria M Belongs to the ompA family ompA - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA DYD3_k127_6720439_1 1254432.SCE1572_49395 2.353e-32 132.0 COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,42RN3@68525|delta/epsilon subdivisions,2X6YZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ABC transporter - - 3.6.3.34 ko:K02013,ko:K05776 ko02010,map02010 M00189,M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran DYD3_k127_6720439_0 1127673.GLIP_3550 7.004e-149 486.0 COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RNQ7@1236|Gammaproteobacteria,468IG@72275|Alteromonadaceae 1236|Gammaproteobacteria V MatE yeeO GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - - - - - - - - - - MatE DYD3_k127_6720439_2 1379270.AUXF01000005_gene551 1.027e-27 117.0 COG0412@1|root,COG0412@2|Bacteria,1ZUSZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH DYD3_k127_6726349_4 1245471.PCA10_38100 1.039e-61 224.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1YD0C@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria V MatE pmpM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE DYD3_k127_6726349_0 1304275.C41B8_10043 4.655e-168 541.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed fadI - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N DYD3_k127_6726349_1 1122604.JONR01000007_gene2924 2.345e-164 536.0 COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1X57M@135614|Xanthomonadales 135614|Xanthomonadales E Sodium alanine symporter - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp DYD3_k127_6726349_5 1282876.BAOK01000001_gene1175 1.27e-28 122.0 COG3409@1|root,COG3409@2|Bacteria,1NP3I@1224|Proteobacteria,2UM8V@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - DYD3_k127_6726349_2 765912.Thimo_1839 6.501e-129 422.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales 135613|Chromatiales H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase DYD3_k127_6726349_3 1384054.N790_14535 3.775e-79 274.0 COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,1X448@135614|Xanthomonadales 135614|Xanthomonadales L Exodeoxyribonuclease IX exo - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N DYD3_k127_6726349_6 247633.GP2143_04615 1.262e-07 57.0 COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,1J5ZC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG0258 5'-3' exonuclease (including N-terminal domain of PolI) exo - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N DYD3_k127_6743841_0 1033802.SSPSH_003548 0.0 1030.0 COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Glutamate synthase gltB GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557 GATase_2,GXGXG,Glu_syn_central,Glu_synthase DYD3_k127_6757269_1 87626.PTD2_03236 4.921e-34 136.0 COG4254@1|root,COG4254@2|Bacteria,1RJR0@1224|Proteobacteria,1S8WR@1236|Gammaproteobacteria,2Q1P5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - FecR DYD3_k127_6757269_0 1535422.ND16A_2986 2.229e-260 821.0 COG0492@1|root,COG0664@1|root,COG1142@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,COG1142@2|Bacteria,1QWC6@1224|Proteobacteria,1RPDJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein hyfA - - ko:K12136 - - - - ko00000,ko01000 - - iEcolC_1368.EcolC_1195,iUMNK88_1353.UMNK88_3076 Fer4,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9,Pyr_redox_2,Pyr_redox_3,cNMP_binding DYD3_k127_6770280_0 519989.ECTPHS_03061 2.577e-126 413.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1WW3U@135613|Chromatiales 135613|Chromatiales T PFAM PhoH family protein - - - ko:K06217 - - - - ko00000 - - - PhoH DYD3_k127_6770280_3 349124.Hhal_0891 7.483e-37 144.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,1WYGP@135613|Chromatiales 135613|Chromatiales J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 DYD3_k127_6770280_2 472759.Nhal_3898 2.708e-82 282.0 COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1WW4G@135613|Chromatiales 135613|Chromatiales P PFAM CBS domain - - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC DYD3_k127_6770280_1 765913.ThidrDRAFT_2752 7.546e-103 354.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales 135613|Chromatiales M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase DYD3_k127_6811660_0 519989.ECTPHS_04069 1.551e-166 540.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales 135613|Chromatiales S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN DYD3_k127_6811660_2 713587.THITH_00935 9.243e-24 104.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Binds directly to 16S ribosomal RNA rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p DYD3_k127_6811660_1 1288826.MSNKSG1_18425 2.641e-139 452.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,4647H@72275|Alteromonadaceae 1236|Gammaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 DYD3_k127_6826700_14 2340.JV46_19650 1.22e-12 69.0 COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,1RQ9A@1236|Gammaproteobacteria,1J616@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NapC/NirT cytochrome c family, N-terminal region - - - ko:K02569 - - - - ko00000 - - - Cytochrom_NNT DYD3_k127_6826700_13 1265313.HRUBRA_02293 9.851e-22 102.0 COG3631@1|root,COG3631@2|Bacteria,1NA13@1224|Proteobacteria,1SSSD@1236|Gammaproteobacteria,1JB6W@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 DYD3_k127_6826700_12 1286106.MPL1_01637 1.378e-39 151.0 COG0517@1|root,COG0517@2|Bacteria,1QTZR@1224|Proteobacteria,1S7SY@1236|Gammaproteobacteria,4614G@72273|Thiotrichales 72273|Thiotrichales S CBS domain - - - - - - - - - - - - CBS DYD3_k127_6826700_15 768066.HELO_2221 3.456e-07 54.0 COG2991@1|root,COG2991@2|Bacteria,1NI0R@1224|Proteobacteria,1SGJF@1236|Gammaproteobacteria,1XM95@135619|Oceanospirillales 135619|Oceanospirillales S protein conserved in bacteria - - - ko:K05952 - - - - ko00000 - - - NqrM DYD3_k127_6826700_8 1283300.ATXB01000001_gene1427 2.193e-91 311.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XEB2@135618|Methylococcales 135618|Methylococcales H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - - - - - - - - - - ApbE DYD3_k127_6826700_1 1283300.ATXB01000001_gene1426 6.611e-184 590.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1XECA@135618|Methylococcales 135618|Methylococcales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway nqrF - 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 DYD3_k127_6826700_6 1026882.MAMP_01769 5.9e-98 325.0 COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,4608S@72273|Thiotrichales 72273|Thiotrichales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrE - 1.6.5.8 ko:K00350 - - - - ko00000,ko01000 - - - Rnf-Nqr DYD3_k127_6826700_7 1026882.MAMP_01767 1.676e-95 321.0 COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,4602B@72273|Thiotrichales 72273|Thiotrichales C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD - 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr DYD3_k127_6826700_9 2340.JV46_13700 1.84e-76 266.0 COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,1J5HE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC - 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind DYD3_k127_6826700_3 2340.JV46_13710 1.207e-169 553.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1T20Y@1236|Gammaproteobacteria,1JC0A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrB - 1.6.5.8 ko:K00347,ko:K03614 - - - - ko00000,ko01000 - - - NQR2_RnfD_RnfE DYD3_k127_6826700_4 644801.Psest_1655 5.632e-164 527.0 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1Z24H@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB DYD3_k127_6826700_10 1089552.KI911559_gene1680 2.224e-66 239.0 COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,2UAN7@28211|Alphaproteobacteria,2JSRK@204441|Rhodospirillales 204441|Rhodospirillales H UbiA prenyltransferase family - - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA DYD3_k127_6826700_0 2340.JV46_26720 3.401e-318 979.0 COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,1RMC3@1236|Gammaproteobacteria,1JARP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Nickel-dependent hydrogenase hydB - 1.12.5.1,1.12.99.6 ko:K05922,ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases DYD3_k127_6826700_5 296591.Bpro_1188 1.501e-139 458.0 COG0247@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0479@2|Bacteria,1MUMH@1224|Proteobacteria,2WBZQ@28216|Betaproteobacteria,4AIM6@80864|Comamonadaceae 28216|Betaproteobacteria C 4Fe-4S dicluster domain - - - ko:K21834 - - - - ko00000 - - - CCG,Fer4_8 DYD3_k127_6826700_11 396588.Tgr7_1268 1.896e-60 220.0 COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,1S05R@1236|Gammaproteobacteria,1WXBW@135613|Chromatiales 135613|Chromatiales C nitrate reductase activity - - - - - - - - - - - - - DYD3_k127_6826700_2 1049564.TevJSym_bc00360 2.557e-170 542.0 COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,1JB7M@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NiFe/NiFeSe hydrogenase small subunit C-terminal - - 1.12.99.6 ko:K06282 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFe_hyd_SSU_C,Oxidored_q6 DYD3_k127_68546_0 1232410.KI421421_gene3529 1.975e-276 887.0 COG2067@1|root,COG2885@1|root,COG2067@2|Bacteria,COG2885@2|Bacteria,1MY5K@1224|Proteobacteria 1224|Proteobacteria I long-chain fatty acid transport protein - - - - - - - - - - - - DUF11 DYD3_k127_6893098_1 1234364.AMSF01000075_gene1935 7.428e-40 155.0 COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,1S81F@1236|Gammaproteobacteria,1X5UH@135614|Xanthomonadales 135614|Xanthomonadales S mRNA catabolic process - - - - - - - - - - - - - DYD3_k127_6893098_0 314278.NB231_06131 1.588e-115 385.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales 135613|Chromatiales M TIGRFAM penicillin-binding protein, 1A - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase DYD3_k127_6893650_0 2340.JV46_24910 2.319e-93 313.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1J5ZG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313 Inositol_P DYD3_k127_6893650_1 1380387.JADM01000002_gene2153 1.964e-53 208.0 COG0637@1|root,COG0637@2|Bacteria,1QTT8@1224|Proteobacteria,1T1GC@1236|Gammaproteobacteria,1XRU5@135619|Oceanospirillales 135619|Oceanospirillales S hydrolase - - 3.1.3.5 ko:K20881 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 DYD3_k127_6893650_2 550540.Fbal_3563 3.452e-10 63.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria 1236|Gammaproteobacteria JKL DEAD-box RNA helicase involved in rhlB GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 ko:K03732 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C,RhlB DYD3_k127_6903769_1 1027273.GZ77_16690 5.144e-62 220.0 28RZD@1|root,2ZEBA@2|Bacteria,1RBEH@1224|Proteobacteria,1RP8T@1236|Gammaproteobacteria,1XIH6@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - DYD3_k127_6903769_0 861299.J421_1510 1.872e-162 528.0 COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes 142182|Gemmatimonadetes J Amidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase DYD3_k127_6903769_2 767434.Fraau_0298 4.665e-26 109.0 COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,1S2WK@1236|Gammaproteobacteria,1X5N0@135614|Xanthomonadales 135614|Xanthomonadales M Methyltransferase - - - - - - - - - - - - PCMT DYD3_k127_6904943_3 225937.HP15_1560 4.657e-10 60.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,464B9@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs iorB - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,TAT_signal DYD3_k127_6904943_0 1117315.AHCA01000014_gene3888 6.849e-77 273.0 2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,1RRIP@1236|Gammaproteobacteria,2PZK5@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_6904943_2 1120953.AUBH01000008_gene228 1.369e-37 151.0 COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,1S6US@1236|Gammaproteobacteria,46871@72275|Alteromonadaceae 1236|Gammaproteobacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - - DYD3_k127_6904943_1 1121015.N789_01640 1.76e-69 256.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X2Z4@135614|Xanthomonadales 135614|Xanthomonadales T phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,HAMP,dCache_3 DYD3_k127_6915526_3 1027273.GZ77_06715 3.458e-91 310.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1XHD6@135619|Oceanospirillales 135619|Oceanospirillales K in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon cysB - - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate DYD3_k127_6915526_2 1120953.AUBH01000010_gene172 2.667e-91 306.0 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,1RNC5@1236|Gammaproteobacteria,46452@72275|Alteromonadaceae 1236|Gammaproteobacteria EH Belongs to the PAPS reductase family. CysH subfamily cysH GO:0000103,GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019379,GO:0019419,GO:0044237,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_3025,iECABU_c1320.ECABU_c30290,iECNA114_1301.ECNA114_2793,iECO103_1326.ECO103_3306,iECP_1309.ECP_2736,iECSF_1327.ECSF_2551,iETEC_1333.ETEC_2955,iLF82_1304.LF82_0415,iNRG857_1313.NRG857_13505,iSDY_1059.SDY_2964,ic_1306.c3321 PAPS_reduct DYD3_k127_6915526_0 1242864.D187_008316 5.37e-216 683.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q2M@68525|delta/epsilon subdivisions 1224|Proteobacteria C Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate cysI GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016673,GO:0019419,GO:0020037,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0097159,GO:1901363 1.7.7.1,1.8.1.2,1.8.7.1 ko:K00366,ko:K00381,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00531 R00790,R00858,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_3037,iECH74115_1262.ECH74115_4017,iECIAI1_1343.ECIAI1_2867,iECNA114_1301.ECNA114_2794,iECO103_1326.ECO103_3307,iECSE_1348.ECSE_3019,iECSF_1327.ECSF_2552,iECSP_1301.ECSP_3712,iECUMN_1333.ECUMN_3091,iECW_1372.ECW_m2971,iECs_1301.ECs3618,iEKO11_1354.EKO11_1005,iEcE24377_1341.EcE24377A_3065,iSFV_1184.SFV_2742,iSbBS512_1146.SbBS512_E3112,iWFL_1372.ECW_m2971,iZ_1308.Z4073 NIR_SIR,NIR_SIR_ferr DYD3_k127_6915526_1 342610.Patl_4039 1.216e-147 496.0 COG0369@1|root,COG0369@2|Bacteria,1MWYV@1224|Proteobacteria,1S126@1236|Gammaproteobacteria,2Q0VT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria C Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component cysJ GO:0000166,GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016667,GO:0016668,GO:0032553,GO:0032991,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - iECO26_1355.ECO26_3835,iECSE_1348.ECSE_3020,iECW_1372.ECW_m2972,iEKO11_1354.EKO11_1004,iEcE24377_1341.EcE24377A_3066,iEcolC_1368.EcolC_0948,iWFL_1372.ECW_m2972 FAD_binding_1,Flavodoxin_1,NAD_binding_1 DYD3_k127_6915526_4 247633.GP2143_15821 9.324e-22 97.0 2BKN5@1|root,32F3J@2|Bacteria,1RIMC@1224|Proteobacteria,1S6Q3@1236|Gammaproteobacteria,1J7D1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp DYD3_k127_6931812_0 765914.ThisiDRAFT_2334 3.386e-211 686.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1WXN6@135613|Chromatiales 135613|Chromatiales J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 DYD3_k127_6931812_1 1049564.TevJSym_al00370 4.013e-93 320.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1J54Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 DYD3_k127_6941433_6 565045.NOR51B_1620 1.508e-25 111.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) paaF - - - - - - - - - - - AMP-binding,AMP-binding_C_2 DYD3_k127_6941433_4 566466.NOR53_3223 1.88e-73 252.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1T28J@1236|Gammaproteobacteria,1JAMM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S R COG0655 Multimeric flavodoxin WrbA - - - - - - - - - - - - FMN_red DYD3_k127_6941433_3 566466.NOR53_3577 4.716e-84 282.0 COG0346@1|root,COG0346@2|Bacteria,1RAC9@1224|Proteobacteria,1SZYX@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase DYD3_k127_6941433_0 566466.NOR53_3608 5.021e-297 942.0 COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1RYC0@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec DYD3_k127_6941433_2 566466.NOR53_3351 6.123e-89 300.0 COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,1S2ER@1236|Gammaproteobacteria 1236|Gammaproteobacteria C citrate synthase - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt DYD3_k127_6941433_5 1122137.AQXF01000004_gene1587 5.514e-50 188.0 COG2267@1|root,COG2267@2|Bacteria,1QWE3@1224|Proteobacteria,2UDWQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 DYD3_k127_6941433_1 566466.NOR53_3212 4.527e-101 338.0 COG1414@1|root,COG1414@2|Bacteria,1QYTM@1224|Proteobacteria,1RUTM@1236|Gammaproteobacteria,1J6BQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K02624 - - - - ko00000,ko03000 - - - HTH_IclR,IclR DYD3_k127_6941433_7 1117647.M5M_01075 0.0003166 44.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RWRX@1236|Gammaproteobacteria,1J6C2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria KLT Sulfatase-modifying factor enzyme 1 - - 2.7.11.1 ko:K11912 ko02025,ko03070,map02025,map03070 - - - ko00000,ko00001,ko01000,ko01001,ko02044 - - - FGE-sulfatase DYD3_k127_6962297_0 314285.KT71_02502 9.68e-84 287.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Methyltransferase - - - - - - - - - - - - - DYD3_k127_6962297_1 1002339.HMPREF9373_1960 4.442e-67 235.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,1S2I8@1236|Gammaproteobacteria,3NJBZ@468|Moraxellaceae 1236|Gammaproteobacteria G Glutathione S-transferase, N-terminal domain maiA - 5.2.1.2,5.2.1.4 ko:K01800,ko:K01801 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181,R03868 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3 DYD3_k127_6989861_1 1463854.JOHT01000003_gene6163 5.132e-15 82.0 COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria 201174|Actinobacteria K belongs to the sigma-70 factor family, ECF subfamily sigM GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_6989861_0 314264.ROS217_12646 4.955e-91 313.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,46QMS@74030|Roseovarius 28211|Alphaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE DYD3_k127_6989861_2 1123247.AUIJ01000001_gene1779 0.0004827 43.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type molybdate transport system, permease component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 DYD3_k127_7005514_0 713587.THITH_17365 7.246e-137 479.0 COG0574@1|root,COG3173@1|root,COG0574@2|Bacteria,COG3173@2|Bacteria,1Q33X@1224|Proteobacteria,1RNSN@1236|Gammaproteobacteria 1236|Gammaproteobacteria GT COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 ko:K01007,ko:K21787 ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00374,M00837,M00838 R00199,R11662,R11673 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N DYD3_k127_7005514_2 713587.THITH_17370 4.102e-61 216.0 COG0575@1|root,COG0575@2|Bacteria 2|Bacteria I Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 ko:K00981,ko:K19664 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799,R08966 RC00002 ko00000,ko00001,ko00002,ko01000 - - iLJ478.TM1397 CTP_transf_1,CarS-like DYD3_k127_7005514_3 1492737.FEM08_05330 9.315e-43 169.0 COG3239@1|root,COG3239@2|Bacteria 2|Bacteria I unsaturated fatty acid biosynthetic process - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase DYD3_k127_7005514_1 215803.DB30_4561 3.444e-86 294.0 COG0451@1|root,COG0451@2|Bacteria,1RBSM@1224|Proteobacteria,42XUG@68525|delta/epsilon subdivisions,2WTSY@28221|Deltaproteobacteria,2YX8Q@29|Myxococcales 28221|Deltaproteobacteria GM NAD dependent epimerase/dehydratase family - - 1.3.1.45 ko:K05281 ko00943,ko01110,map00943,map01110 - R06562,R06563,R07747,R07751 RC00805 ko00000,ko00001,ko01000 - - - Epimerase DYD3_k127_7005753_2 314278.NB231_03045 2.785e-50 185.0 COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,1WWCY@135613|Chromatiales 135613|Chromatiales G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 DYD3_k127_7005753_1 1316936.K678_11775 5.118e-293 917.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2TR5K@28211|Alphaproteobacteria,2JPD9@204441|Rhodospirillales 204441|Rhodospirillales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 DYD3_k127_7005753_0 1049564.TevJSym_at00530 3.502e-297 927.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1J8TN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase DYD3_k127_7006702_1 479434.Sthe_3109 1.261e-151 499.0 COG0578@1|root,COG0578@2|Bacteria,2G8C0@200795|Chloroflexi,27Y8H@189775|Thermomicrobia 189775|Thermomicrobia C C-terminal domain of alpha-glycerophosphate oxidase - - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C DYD3_k127_7006702_0 391937.NA2_11330 1.004e-156 508.0 COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,43I2D@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh DYD3_k127_7006702_2 331869.BAL199_12066 1.651e-125 415.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,4BPWJ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA DYD3_k127_7006702_3 765912.Thimo_0383 6.47e-34 136.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,1WXGS@135613|Chromatiales 135613|Chromatiales E TIGRFAM Acetolactate synthase, small subunit - - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT_5,ALS_ss_C DYD3_k127_7009134_0 396588.Tgr7_2960 2.753e-107 354.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1WW0F@135613|Chromatiales 135613|Chromatiales J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C DYD3_k127_7009134_1 158822.LH89_16770 4.299e-60 214.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212 Ham1p_like DYD3_k127_7009134_2 743720.Psefu_0298 1.558e-32 130.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,1YV0W@136845|Pseudomonas putida group 1236|Gammaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound yggW GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM DYD3_k127_7015758_0 420324.KI911965_gene577 2.612e-220 697.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,1JTYW@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM pyruvate ferredoxin flavodoxin oxidoreductase MA20_06130 - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C DYD3_k127_7015758_1 1382303.JPOM01000001_gene1378 5.364e-106 351.0 COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2TSYY@28211|Alphaproteobacteria,2KFGU@204458|Caulobacterales 204458|Caulobacterales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD3_k127_7022406_0 880073.Calab_1281 4.532e-90 305.0 COG1257@1|root,COG1577@1|root,COG1257@2|Bacteria,COG1577@2|Bacteria,2NQ9C@2323|unclassified Bacteria 2|Bacteria I Hydroxymethylglutaryl-coenzyme A reductase mvk - 1.1.1.34,1.1.1.88,2.3.1.9,2.3.3.10,2.7.1.36 ko:K00021,ko:K00054,ko:K00626,ko:K00869,ko:K01641 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,ko04146,ko04152,ko04976,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020,map04146,map04152,map04976 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R01978,R02081,R02082,R02245 RC00002,RC00004,RC00017,RC00326,RC00503,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,HMG-CoA_red DYD3_k127_7022406_2 666685.R2APBS1_3946 3.49e-43 172.0 COG1577@1|root,COG1577@2|Bacteria,1N400@1224|Proteobacteria,1SC29@1236|Gammaproteobacteria,1XAB2@135614|Xanthomonadales 135614|Xanthomonadales I GHMP kinases N terminal domain - - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_N DYD3_k127_7022406_1 666685.R2APBS1_3945 3.298e-50 184.0 COG3407@1|root,COG3407@2|Bacteria,1N5EZ@1224|Proteobacteria,1S19T@1236|Gammaproteobacteria,1X9HF@135614|Xanthomonadales 135614|Xanthomonadales I GHMP kinases N terminal domain - - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_N DYD3_k127_7028398_2 1298867.AUES01000018_gene4117 7.408e-91 302.0 COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,2TVAP@28211|Alphaproteobacteria,3JRAG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Sodium/calcium exchanger protein - - - ko:K07300 - - - - ko00000,ko02000 2.A.19 - - Na_Ca_ex DYD3_k127_7028398_3 1298867.AUES01000063_gene24 1.906e-59 213.0 COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S VIT family - - - - - - - - - - - - VIT1 DYD3_k127_7028398_1 1242864.D187_000213 7.218e-120 409.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria 28221|Deltaproteobacteria M TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - MFS_1,OEP DYD3_k127_7028398_0 497964.CfE428DRAFT_1155 2.902e-138 449.0 COG1566@1|root,COG1566@2|Bacteria,46TG9@74201|Verrucomicrobia 74201|Verrucomicrobia V Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2 DYD3_k127_7028398_4 1396141.BATP01000002_gene4799 5.643e-44 166.0 2DHJ6@1|root,3000S@2|Bacteria,46VCS@74201|Verrucomicrobia,2IVUB@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF3302) - - - - - - - - - - - - DUF3302 DYD3_k127_7028398_5 679897.HMU02210 5.539e-27 116.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2YMTK@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf DYD3_k127_7028925_4 572477.Alvin_1384 6.903e-113 374.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales 135613|Chromatiales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg DYD3_k127_7028925_8 713586.KB900536_gene3030 2.87e-47 177.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1WY2F@135613|Chromatiales 135613|Chromatiales O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE DYD3_k127_7028925_1 396588.Tgr7_0972 2.12e-317 982.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales 135613|Chromatiales O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 DYD3_k127_7028925_3 713586.KB900536_gene3032 6.853e-156 500.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1WWEM@135613|Chromatiales 135613|Chromatiales O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG DYD3_k127_7028925_7 1335757.SPICUR_05045 6.199e-59 214.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1WXGX@135613|Chromatiales 135613|Chromatiales E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N DYD3_k127_7028925_2 396588.Tgr7_0975 8.918e-173 549.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1WXI6@135613|Chromatiales 135613|Chromatiales F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase DYD3_k127_7028925_0 187272.Mlg_1981 0.0 1603.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1WVW8@135613|Chromatiales 135613|Chromatiales EF Belongs to the CarB family carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS DYD3_k127_7028925_5 519989.ECTPHS_06997 2.871e-68 235.0 COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales 135613|Chromatiales K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N DYD3_k127_7028925_9 1442599.JAAN01000031_gene1345 4.056e-22 100.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1X7GX@135614|Xanthomonadales 135614|Xanthomonadales J RNA-binding protein - - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY DYD3_k127_7028925_6 1408444.JHYC01000032_gene178 2.589e-67 237.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1JDAN@118969|Legionellales 118969|Legionellales J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ DYD3_k127_7037451_0 426355.Mrad2831_4874 1.513e-159 527.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2USBQ@28211|Alphaproteobacteria,1JRU2@119045|Methylobacteriaceae 28211|Alphaproteobacteria V PFAM ABC transporter transmembrane region - - 3.6.3.27 ko:K06021,ko:K13409,ko:K20344 ko02010,ko02024,ko04626,map02010,map02024,map04626 M00339 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02044 3.A.1.110,3.A.1.112 - - ABC_membrane,ABC_tran,Peptidase_C39 DYD3_k127_7037451_1 414684.RC1_2734 9.421e-47 186.0 COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,2U45N@28211|Alphaproteobacteria,2JXA5@204441|Rhodospirillales 204441|Rhodospirillales M HlyD family secretion protein - - - ko:K13408 ko04626,map04626 M00339 - - ko00000,ko00001,ko00002,ko02000,ko02044 8.A.1 - - Biotin_lipoyl_2,HlyD_3 DYD3_k127_7046085_3 247639.MGP2080_01361 1.046e-99 334.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1J591@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 DYD3_k127_7046085_4 1448139.AI20_13430 5.517e-76 265.0 COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1Y3GJ@135624|Aeromonadales 135624|Aeromonadales S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K06879 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF,QueF_N DYD3_k127_7046085_1 1121013.P873_12390 8.358e-151 486.0 COG1820@1|root,COG1820@2|Bacteria,1QUJ0@1224|Proteobacteria,1T26K@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation iadA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008270,GO:0008798,GO:0016787,GO:0019538,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K01305 - - - - ko00000,ko01000,ko01002 - - - Amidohydro_1,Amidohydro_3 DYD3_k127_7046085_2 1121015.N789_00870 1.796e-101 338.0 COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria 1236|Gammaproteobacteria PQ Belongs to the peptidase S51 family - - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 DYD3_k127_7046085_0 391625.PPSIR1_16165 0.0 1188.0 COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,42PUY@68525|delta/epsilon subdivisions,2WM1C@28221|Deltaproteobacteria,2YXTJ@29|Myxococcales 28221|Deltaproteobacteria HJ RimK-like ATP-grasp domain - - 6.3.2.29,6.3.2.30 ko:K03802 - - - - ko00000,ko01000 - - - Mur_ligase_C,Mur_ligase_M,RimK DYD3_k127_7049555_1 375286.mma_2596 4.962e-87 293.0 COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VUIT@28216|Betaproteobacteria,476WJ@75682|Oxalobacteraceae 28216|Betaproteobacteria H Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA DYD3_k127_7049555_0 1120965.AUBV01000001_gene3486 4.026e-232 754.0 COG2866@1|root,COG2866@2|Bacteria,4NGIE@976|Bacteroidetes,47N2M@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 DYD3_k127_7069917_2 1340493.JNIF01000003_gene3751 3.207e-36 141.0 COG1858@1|root,COG1858@2|Bacteria,3Y46D@57723|Acidobacteria 57723|Acidobacteria P Di-haem cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C DYD3_k127_7069917_1 1254432.SCE1572_16805 7.56e-44 170.0 29SNW@1|root,30DUI@2|Bacteria,1RDGS@1224|Proteobacteria,437Z9@68525|delta/epsilon subdivisions,2X398@28221|Deltaproteobacteria,2YUWX@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_7069917_0 1128912.GMES_2982 5.715e-53 191.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,464IE@72275|Alteromonadaceae 1236|Gammaproteobacteria C Glycerophosphoryl diester phosphodiesterase family glpQ GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119 GDPD DYD3_k127_7071595_8 177437.HRM2_28310 9.856e-22 98.0 COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,42NEP@68525|delta/epsilon subdivisions,2WIVJ@28221|Deltaproteobacteria,2MIV0@213118|Desulfobacterales 28221|Deltaproteobacteria C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm DYD3_k127_7071595_3 518766.Rmar_2430 6.419e-65 234.0 COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes 976|Bacteroidetes C PFAM Cytochrome C - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 DYD3_k127_7071595_0 1121935.AQXX01000127_gene1210 5.442e-222 695.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XHHJ@135619|Oceanospirillales 1224|Proteobacteria E Belongs to the glutamine synthetase family glnA1 - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C DYD3_k127_7071595_4 314287.GB2207_09066 2.19e-46 171.0 COG0454@1|root,COG0456@2|Bacteria,1N506@1224|Proteobacteria,1S97J@1236|Gammaproteobacteria,1JAUH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 DYD3_k127_7071595_7 190650.CC_1080 1.964e-29 122.0 COG2197@1|root,COG2197@2|Bacteria,1N0NK@1224|Proteobacteria,2UCCE@28211|Alphaproteobacteria,2KIW6@204458|Caulobacterales 204458|Caulobacterales KT PFAM regulatory protein LuxR - - - - - - - - - - - - GerE DYD3_k127_7071595_6 509190.Cseg_3174 5.371e-40 156.0 2CB8S@1|root,30PE6@2|Bacteria,1RG91@1224|Proteobacteria,2U7BM@28211|Alphaproteobacteria,2KGWR@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF4199) - - - - - - - - - - - - DUF4199 DYD3_k127_7071595_1 438753.AZC_0804 2.582e-168 539.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2TQT2@28211|Alphaproteobacteria,3EYVN@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2,cNMP_binding DYD3_k127_7071595_9 518766.Rmar_0390 3.936e-08 61.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11 DYD3_k127_7071595_2 396588.Tgr7_2752 4.56e-70 246.0 COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,1RQIA@1236|Gammaproteobacteria,1WWVB@135613|Chromatiales 135613|Chromatiales S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 DYD3_k127_7071595_5 1123269.NX02_18175 1.745e-45 168.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,2K06B@204457|Sphingomonadales 204457|Sphingomonadales P chromate transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp DYD3_k127_7073683_0 1037409.BJ6T_23810 2.12e-260 808.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 DYD3_k127_7073683_1 1037409.BJ6T_23800 8.387e-123 404.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR,SCP2 DYD3_k127_7073683_2 443143.GM18_2019 1.326e-64 229.0 COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,42RPV@68525|delta/epsilon subdivisions,2WNQC@28221|Deltaproteobacteria 28221|Deltaproteobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran DYD3_k127_7078124_7 1144342.PMI40_00447 1.725e-31 128.0 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,472HV@75682|Oxalobacteraceae 28216|Betaproteobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N DYD3_k127_7078124_2 1123401.JHYQ01000016_gene3019 7.947e-118 400.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,460GP@72273|Thiotrichales 72273|Thiotrichales J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA - - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB DYD3_k127_7078124_10 1131553.JIBI01000036_gene2047 1.775e-07 60.0 29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,3731M@32003|Nitrosomonadales 28216|Betaproteobacteria S Domain of unknown function (DUF4390) - - - - - - - - - - - - DUF4390 DYD3_k127_7078124_0 187272.Mlg_2624 1.925e-182 595.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales 135613|Chromatiales T signal transduction histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS_4,PAS_8 DYD3_k127_7078124_1 765912.Thimo_1242 2.739e-141 462.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat DYD3_k127_7078124_9 1267534.KB906756_gene149 8.995e-15 83.0 2ESJ3@1|root,33K3T@2|Bacteria,3Y8Y6@57723|Acidobacteria,2JNTF@204432|Acidobacteriia 204432|Acidobacteriia S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM DYD3_k127_7078124_6 1121022.ABENE_16000 2.714e-38 151.0 COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2UBW9@28211|Alphaproteobacteria,2KJIK@204458|Caulobacterales 204458|Caulobacterales S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 DYD3_k127_7078124_3 62928.azo2613 2.551e-55 199.0 COG3791@1|root,COG3791@2|Bacteria,1RFA9@1224|Proteobacteria,2VRW5@28216|Betaproteobacteria 28216|Betaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA DYD3_k127_7078124_4 1121904.ARBP01000026_gene629 5.925e-46 169.0 COG3832@1|root,COG3832@2|Bacteria,4NRDQ@976|Bacteroidetes,47VV2@768503|Cytophagia 976|Bacteroidetes S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD3_k127_7078124_5 379066.GAU_2211 1.454e-44 166.0 2D7HY@1|root,32TP2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF1801 DYD3_k127_7078124_8 1380387.JADM01000013_gene1329 1.177e-16 80.0 2B14M@1|root,31TIF@2|Bacteria,1RH0J@1224|Proteobacteria,1S6U0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF2938) - - - - - - - - - - - - DUF2938 DYD3_k127_710014_0 1123257.AUFV01000002_gene2641 4.729e-62 227.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1X3M3@135614|Xanthomonadales 135614|Xanthomonadales L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB - 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C DYD3_k127_710014_5 1137799.GZ78_13395 1.649e-12 76.0 2CBG9@1|root,32RTB@2|Bacteria,1R86M@1224|Proteobacteria,1RNNN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Type II secretion system, protein N gspN GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02463 ko05111,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSN DYD3_k127_710014_4 713586.KB900536_gene2374 1.389e-12 76.0 COG3149@1|root,COG3149@2|Bacteria,1N8VZ@1224|Proteobacteria,1SCSU@1236|Gammaproteobacteria,1WZQA@135613|Chromatiales 135613|Chromatiales U Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM DYD3_k127_710014_3 1123256.KB907927_gene1682 5.213e-32 141.0 COG3297@1|root,COG3297@2|Bacteria,1NVVW@1224|Proteobacteria,1S01F@1236|Gammaproteobacteria,1X6HI@135614|Xanthomonadales 135614|Xanthomonadales U GspL periplasmic domain - - - - - - - - - - - - GspL_C,T2SSL DYD3_k127_710014_1 395493.BegalDRAFT_3088 2.379e-58 216.0 COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,460PF@72273|Thiotrichales 72273|Thiotrichales U Type II secretion system (T2SS), protein K - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK DYD3_k127_710014_2 1123257.AUFV01000001_gene1927 2.11e-34 139.0 COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1X777@135614|Xanthomonadales 135614|Xanthomonadales U Type II secretion system (T2SS), protein J - - - - - - - - - - - - N_methyl,T2SSJ DYD3_k127_7100864_2 930169.B5T_02430 2.084e-75 257.0 COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,1XHT2@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the UPF0176 family - - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C DYD3_k127_7100864_4 686340.Metal_3856 2.92e-27 117.0 COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,1SDJW@1236|Gammaproteobacteria,1XFQ9@135618|Methylococcales 135618|Methylococcales P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - - DYD3_k127_7100864_0 1125863.JAFN01000001_gene1462 1.345e-300 940.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC copF - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase,YHS DYD3_k127_7100864_3 565045.NOR51B_1101 6.091e-66 236.0 COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,1RZEY@1236|Gammaproteobacteria,1J66N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Copper resistance protein B precursor (CopB) - - - ko:K07233 - - - - ko00000 - - - CopB DYD3_k127_7100864_1 1122613.ATUP01000002_gene2484 1.068e-215 685.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,43X7Y@69657|Hyphomonadaceae 28211|Alphaproteobacteria Q Copper-binding protein copA - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 DYD3_k127_7100864_5 1031711.RSPO_c01703 1.55e-12 69.0 COG5570@1|root,COG5570@2|Bacteria,1R3J1@1224|Proteobacteria,2VXMA@28216|Betaproteobacteria,1K9K9@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF465) - - - - - - - - - - - - DUF465 DYD3_k127_7134516_3 1122236.KB905141_gene633 1.268e-121 395.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,2KMJJ@206350|Nitrosomonadales 206350|Nitrosomonadales S MmgE/PrpD family - - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD DYD3_k127_7134516_0 553385.JEMF01000050_gene2125 4.168e-160 512.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,1XI36@135619|Oceanospirillales 135619|Oceanospirillales C Belongs to the citrate synthase family prpC - 2.3.3.5 ko:K01659 ko00640,map00640 - R00931 RC00004,RC00406,RC02827 ko00000,ko00001,ko01000 - - - Citrate_synt DYD3_k127_7134516_2 395493.BegalDRAFT_1700 5.569e-127 412.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,1RMR5@1236|Gammaproteobacteria,46076@72273|Thiotrichales 72273|Thiotrichales G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30 ko:K03417 ko00640,map00640 - R00409 RC00286,RC00287 ko00000,ko00001,ko01000 - - - PEP_mutase DYD3_k127_7134516_1 566466.NOR53_2673 1.626e-153 501.0 COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1J849@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes clsC GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - ko:K06132 ko00564,ko01100,map00564,map01100 - R11062 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 DYD3_k127_7134516_4 1163617.SCD_n01504 2.318e-121 398.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria 28216|Betaproteobacteria C alcohol dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N DYD3_k127_7134516_5 323261.Noc_2704 1.275e-107 357.0 COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,1RR31@1236|Gammaproteobacteria,1WXBJ@135613|Chromatiales 135613|Chromatiales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B DYD3_k127_7134516_6 1283300.ATXB01000001_gene487 1.143e-38 152.0 COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,1SBJR@1236|Gammaproteobacteria,1XGZN@135618|Methylococcales 135618|Methylococcales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C DYD3_k127_7134516_7 1122603.ATVI01000009_gene2604 2.525e-10 73.0 COG5339@1|root,COG5339@2|Bacteria,1N902@1224|Proteobacteria 1224|Proteobacteria S Bacterial protein of unknown function (DUF945) - - - - - - - - - - - - DUF945 DYD3_k127_7147674_0 713587.THITH_01990 2.018e-188 603.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB DYD3_k127_7147674_3 1163407.UU7_14325 2.373e-45 166.0 COG3288@1|root,COG3288@2|Bacteria,1N0TD@1224|Proteobacteria,1SYB5@1236|Gammaproteobacteria,1X7MI@135614|Xanthomonadales 135614|Xanthomonadales C NADP transhydrogenase - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM DYD3_k127_7147674_1 396588.Tgr7_0268 1.864e-137 447.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1WWTF@135613|Chromatiales 135613|Chromatiales C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM DYD3_k127_7147674_2 713587.THITH_02005 2.725e-83 281.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1WWXG@135613|Chromatiales 135613|Chromatiales L PFAM HNH endonuclease - - - - - - - - - - - - HNH_5 DYD3_k127_714780_1 1122139.KB907865_gene1490 1.593e-103 352.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1XH9W@135619|Oceanospirillales 135619|Oceanospirillales P Belongs to the ABC transporter superfamily - - - ko:K10823,ko:K13896,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00349,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25 - - ABC_tran,oligo_HPY DYD3_k127_714780_2 1033802.SSPSH_000608 1.921e-90 316.0 COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria 1236|Gammaproteobacteria P COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components oppC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - iAF1260.b1245,iB21_1397.B21_01229,iEC55989_1330.EC55989_1342,iECBD_1354.ECBD_2377,iECB_1328.ECB_01219,iECDH10B_1368.ECDH10B_1307,iECDH1ME8569_1439.ECDH1ME8569_1185,iECD_1391.ECD_01219,iECIAI1_1343.ECIAI1_1264,iECO103_1326.ECO103_1345,iECO111_1330.ECO111_1572,iECO26_1355.ECO26_1756,iECSE_1348.ECSE_1293,iECSP_1301.ECSP_1637,iECUMN_1333.ECUMN_1542,iECW_1372.ECW_m1337,iECs_1301.ECs1745,iEKO11_1354.EKO11_2607,iETEC_1333.ETEC_1347,iEcDH1_1363.EcDH1_2403,iEcE24377_1341.EcE24377A_1393,iEcHS_1320.EcHS_A1354,iEcolC_1368.EcolC_2383,iG2583_1286.G2583_1517,iJO1366.b1245,iSSON_1240.SSON_1935,iUMNK88_1353.UMNK88_1565,iWFL_1372.ECW_m1337,iY75_1357.Y75_RS06515,iZ_1308.Z2021 BPD_transp_1,OppC_N DYD3_k127_714780_0 1415779.JOMH01000001_gene331 2.52e-109 362.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1X5Q2@135614|Xanthomonadales 135614|Xanthomonadales EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 DYD3_k127_714780_3 870187.Thini_4469 2.466e-24 104.0 COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,463RT@72273|Thiotrichales 72273|Thiotrichales E Bacterial extracellular solute-binding proteins, family 5 Middle - - - - - - - - - - - - SBP_bac_5 DYD3_k127_7194480_0 1123257.AUFV01000012_gene2983 6.862e-52 184.0 COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,1S4M7@1236|Gammaproteobacteria,1X6D4@135614|Xanthomonadales 135614|Xanthomonadales S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 DYD3_k127_7194480_1 1232410.KI421416_gene2621 4.376e-36 146.0 2EF9T@1|root,3392P@2|Bacteria,1P8J3@1224|Proteobacteria,4324V@68525|delta/epsilon subdivisions,2WYC0@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_7194480_2 156578.ATW7_04252 2.071e-16 81.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase, M16 ptrA - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C DYD3_k127_7201229_2 1227739.Hsw_PA0213 5.158e-24 115.0 COG2865@1|root,COG2865@2|Bacteria,4NRX4@976|Bacteroidetes,47X00@768503|Cytophagia 976|Bacteroidetes K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 DYD3_k127_7201229_1 1384056.N787_03245 2.721e-43 164.0 COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,1X60S@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 DYD3_k127_7201229_0 1211115.ALIQ01000189_gene820 4.179e-63 231.0 COG2334@1|root,COG2334@2|Bacteria,1MXTW@1224|Proteobacteria,2U31H@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Phosphotransferase enzyme family - - - - - - - - - - - - APH DYD3_k127_721580_2 1049564.TevJSym_ac01450 1.938e-171 551.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1J5AY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG0608 Single-stranded DNA-specific exonuclease recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 DYD3_k127_721580_3 1121935.AQXX01000068_gene5863 7.544e-163 518.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1XHPA@135619|Oceanospirillales 135619|Oceanospirillales J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 DYD3_k127_721580_1 1266914.ATUK01000017_gene581 1.632e-217 684.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1WVXY@135613|Chromatiales 135613|Chromatiales J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon DYD3_k127_721580_7 1304275.C41B8_08990 5.878e-31 134.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication ygfZ GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C DYD3_k127_721580_11 316273.XCV2240 8.401e-09 60.0 COG5508@1|root,COG5508@2|Bacteria,1QBN7@1224|Proteobacteria,1SGI9@1236|Gammaproteobacteria,1X8XH@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1674) - - - - - - - - - - - - DUF1674 DYD3_k127_721580_6 391165.GbCGDNIH1_2080 1.18e-31 128.0 COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,2JTDG@204441|Rhodospirillales 204441|Rhodospirillales C COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt DYD3_k127_721580_8 331869.BAL199_10562 9.476e-28 119.0 COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,2U94P@28211|Alphaproteobacteria,4BR1M@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C succinate dehydrogenase sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt DYD3_k127_721580_0 519989.ECTPHS_11050 3.89e-311 964.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales 135613|Chromatiales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C DYD3_k127_721580_4 187272.Mlg_1335 6.352e-138 442.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales 135613|Chromatiales C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_17,Fer4_8 DYD3_k127_721580_9 1123073.KB899244_gene428 2.776e-14 77.0 COG2938@1|root,COG2938@2|Bacteria 2|Bacteria C An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH sdhE GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 1.3.5.1,1.3.5.4 ko:K00240,ko:K09159 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000,ko02048 - - - Sdh5 DYD3_k127_721580_5 187272.Mlg_1339 6.571e-75 257.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1WXBZ@135613|Chromatiales 135613|Chromatiales K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 DYD3_k127_721580_12 380358.XALC_2546 0.000126 52.0 COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SCYE@1236|Gammaproteobacteria,1XCN7@135614|Xanthomonadales 135614|Xanthomonadales T Anti sigma-E protein RseA, N-terminal domain - - - - - - - - - - - - RseA_N DYD3_k127_721580_10 305700.B447_12519 1.282e-11 70.0 COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,2KUKH@206389|Rhodocyclales 206389|Rhodocyclales T Sigma E regulatory protein, MucB RseB rseB - - ko:K03598 - - - - ko00000,ko03021 - - - MucB_RseB,MucB_RseB_C DYD3_k127_7228235_2 1174504.AJTN02000233_gene2577 1.265e-06 51.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,1ZB56@1386|Bacillus 91061|Bacilli P COG1230 Co Zn Cd efflux system component czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux DYD3_k127_7228235_1 401526.TcarDRAFT_0929 8.05e-55 198.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4H4H3@909932|Negativicutes 909932|Negativicutes F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran DYD3_k127_7228235_0 1279038.KB907341_gene1761 5.474e-170 541.0 COG2807@1|root,COG2807@2|Bacteria,1QU0F@1224|Proteobacteria,2TTB4@28211|Alphaproteobacteria,2JPWW@204441|Rhodospirillales 204441|Rhodospirillales P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_724330_3 1211114.ALIP01000121_gene1172 3.361e-72 247.0 COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1X4JP@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_YMGG,OmpA DYD3_k127_724330_4 425104.Ssed_3278 9.555e-34 133.0 COG1278@1|root,COG1463@1|root,COG1278@2|Bacteria,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,1S74Q@1236|Gammaproteobacteria,2QBT4@267890|Shewanellaceae 1236|Gammaproteobacteria Q Protein of unknown function (DUF3465) - - - - - - - - - - - - DUF3465 DYD3_k127_724330_0 1122134.KB893650_gene416 2.996e-114 375.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1XI5W@135619|Oceanospirillales 135619|Oceanospirillales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 DYD3_k127_724330_2 1049564.TevJSym_aa00850 2.264e-79 276.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1J4H6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX DYD3_k127_724330_1 314278.NB231_11259 4.457e-83 281.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,1WWPI@135613|Chromatiales 135613|Chromatiales D TIGRFAM Cell division ATP-binding protein FtsE - - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran DYD3_k127_74504_2 349521.HCH_02013 7.235e-72 246.0 COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria 1224|Proteobacteria L Belongs to the FPG family - - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD3_k127_74504_1 1500890.JQNL01000001_gene2416 1.565e-96 318.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1X3YF@135614|Xanthomonadales 135614|Xanthomonadales F GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI DYD3_k127_74504_0 342610.Patl_3429 2.796e-97 336.0 COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,1RMQK@1236|Gammaproteobacteria 1236|Gammaproteobacteria G gluconolactonase - - - - - - - - - - - - SGL,Str_synth DYD3_k127_746210_6 1122137.AQXF01000002_gene377 3.589e-24 104.0 COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,2UIQ4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - DYD3_k127_746210_5 1122176.KB903531_gene3152 3.409e-26 115.0 COG0406@1|root,COG0406@2|Bacteria,4NQWA@976|Bacteroidetes,1IUI4@117747|Sphingobacteriia 976|Bacteroidetes G Histidine phosphatase superfamily (branch 1) - - - - - - - - - - - - His_Phos_1 DYD3_k127_746210_4 378806.STAUR_2095 1.667e-31 130.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2X9UF@28221|Deltaproteobacteria,2YV67@29|Myxococcales 28221|Deltaproteobacteria O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA DYD3_k127_746210_3 550540.Fbal_3537 2.02e-38 149.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Protein-S-isoprenylcysteine methyltransferase - - - - - - - - - - - - PEMT DYD3_k127_746210_1 1121921.KB898706_gene2488 2.224e-66 238.0 2910Q@1|root,2ZNNC@2|Bacteria,1PCP3@1224|Proteobacteria,1S0BX@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_746210_2 1123517.JOMR01000001_gene1824 1.793e-53 201.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,461CZ@72273|Thiotrichales 72273|Thiotrichales S COGs COG0790 FOG TPR repeat SEL1 subfamily - - - - - - - - - - - - Sel1 DYD3_k127_746210_0 243233.MCA1803 3.872e-83 283.0 COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,1S1VI@1236|Gammaproteobacteria,1XESX@135618|Methylococcales 135618|Methylococcales Q PFAM Dienelactone hydrolase - - - - - - - - - - - - DLH DYD3_k127_75919_0 393595.ABO_2313 8.643e-84 295.0 COG3917@1|root,COG3917@2|Bacteria,1MV6E@1224|Proteobacteria,1RYQD@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q 2-hydroxychromene-2-carboxylate isomerase - - - - - - - - - - - - DSBA DYD3_k127_75919_1 283942.IL0687 3.631e-46 173.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity MA20_24420 - - ko:K06889,ko:K07000 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4,UPF0227 DYD3_k127_768251_0 1049564.TevJSym_af00420 2.897e-219 689.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1J56P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N DYD3_k127_768251_1 396588.Tgr7_2455 2.627e-62 222.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales 135613|Chromatiales C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD3_k127_769035_7 1027273.GZ77_04865 3.752e-06 49.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1XHTY@135619|Oceanospirillales 135619|Oceanospirillales F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase DYD3_k127_769035_0 935567.JAES01000002_gene622 1.565e-219 691.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1X3IX@135614|Xanthomonadales 135614|Xanthomonadales C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase DYD3_k127_769035_1 472759.Nhal_0506 3.768e-203 640.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1WWG7@135613|Chromatiales 135613|Chromatiales G Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK DYD3_k127_769035_4 289376.THEYE_A1836 9.311e-71 246.0 COG0563@1|root,COG0563@2|Bacteria,3J0K3@40117|Nitrospirae 40117|Nitrospirae F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid DYD3_k127_769035_3 519989.ECTPHS_09233 5.437e-72 256.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1WZ40@135613|Chromatiales 135613|Chromatiales J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC DYD3_k127_769035_8 765914.ThisiDRAFT_1753 0.0003573 49.0 2952G@1|root,2ZSF9@2|Bacteria,1NFKJ@1224|Proteobacteria,1S5Q0@1236|Gammaproteobacteria,1WY9R@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD3_k127_769035_2 396588.Tgr7_2447 1.848e-167 537.0 COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1WWVU@135613|Chromatiales 135613|Chromatiales M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate mpl - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M DYD3_k127_769035_6 395493.BegalDRAFT_3005 3.253e-53 196.0 COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,1S54H@1236|Gammaproteobacteria,462T3@72273|Thiotrichales 72273|Thiotrichales S ATP-dependent protease La (LON) substrate-binding domain - - - ko:K07157 - - - - ko00000 - - - LON_substr_bdg DYD3_k127_769035_5 1198232.CYCME_0584 4.242e-54 194.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales 72273|Thiotrichales H PFAM aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD3_k127_769447_2 187272.Mlg_1842 1.756e-91 316.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1WWPM@135613|Chromatiales 135613|Chromatiales D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C DYD3_k127_769447_1 713586.KB900536_gene123 1.143e-142 458.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales 135613|Chromatiales I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA DYD3_k127_769447_0 713586.KB900536_gene124 0.0 1312.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales 135613|Chromatiales L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon DYD3_k127_769447_3 1265502.KB905935_gene3034 1.246e-61 225.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,4AAT9@80864|Comamonadaceae 28216|Betaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII DYD3_k127_769447_4 322710.Avin_38860 9.484e-27 114.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478 LpxB DYD3_k127_780535_1 187272.Mlg_2608 2.152e-115 377.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1WXGA@135613|Chromatiales 135613|Chromatiales C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) - - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding DYD3_k127_780535_0 305900.GV64_17575 6.971e-182 580.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XH5E@135619|Oceanospirillales 135619|Oceanospirillales C 2-oxoglutarate dehydrogenase complex lpdG - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim DYD3_k127_780535_2 1109445.AGSX01000055_gene2728 2.257e-30 123.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1Z1GF@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSFV_1184.SFV_2673 ACT_4,HD_4,RelA_SpoT,TGS DYD3_k127_787222_18 1127673.GLIP_0831 3.805e-15 79.0 2ECN7@1|root,32Y4C@2|Bacteria,1NEKK@1224|Proteobacteria,1SRX6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_787222_19 765869.BDW_06310 3.13e-14 77.0 2EHC2@1|root,33B3X@2|Bacteria,1RGS7@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_787222_23 1443665.JACA01000074_gene1933 0.0001643 45.0 28KHY@1|root,2ZA3C@2|Bacteria 2|Bacteria L HNH endonuclease - - - - - - - - - - - - HNH_3 DYD3_k127_787222_17 1443665.JACA01000074_gene1933 2.453e-18 87.0 28KHY@1|root,2ZA3C@2|Bacteria 2|Bacteria L HNH endonuclease - - - - - - - - - - - - HNH_3 DYD3_k127_787222_20 1161401.ASJA01000005_gene2420 4.912e-08 64.0 COG0477@1|root,COG2814@2|Bacteria,1QKNX@1224|Proteobacteria,2UFJR@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_787222_10 565045.NOR51B_1420 2.474e-62 226.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,1J6BD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR DYD3_k127_787222_1 1116472.MGMO_17c00060 2.883e-232 735.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1XEIK@135618|Methylococcales 135618|Methylococcales KT PFAM RNA polymerase sigma factor 54, interaction - - - - - - - - - - - - HTH_8,PAS_4,Sigma54_activat DYD3_k127_787222_24 1267534.KB906760_gene1563 0.0005888 46.0 29A7N@1|root,2ZX8K@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - DYD3_k127_787222_5 381666.H16_A1815 4.773e-126 418.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,1K5DQ@119060|Burkholderiaceae 28216|Betaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 DYD3_k127_787222_6 211165.AJLN01000061_gene3947 2.084e-116 386.0 COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1JK2A@1189|Stigonemataceae 1117|Cyanobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase DYD3_k127_787222_11 68223.JNZY01000010_gene1556 4.416e-45 182.0 COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria 201174|Actinobacteria E oxidoreductase - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N DYD3_k127_787222_8 251229.Chro_3613 1.902e-81 281.0 COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria 1117|Cyanobacteria U Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP DYD3_k127_787222_4 497964.CfE428DRAFT_3781 1.795e-127 414.0 COG1028@1|root,COG1028@2|Bacteria 497964.CfE428DRAFT_3781|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - DYD3_k127_787222_0 861299.J421_5672 0.0 1328.0 COG2334@1|root,COG2334@2|Bacteria 2|Bacteria S homoserine kinase activity - - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH,Glyco_hydro_63 DYD3_k127_787222_2 1183438.GKIL_0357 2.812e-205 663.0 COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria 1117|Cyanobacteria G Glycogen debranching enzyme - - - - - - - - - - - - GDE_C,GDE_N DYD3_k127_787222_3 861299.J421_1876 4.814e-179 578.0 COG3386@1|root,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL DYD3_k127_787222_9 861299.J421_1875 2.09e-75 263.0 COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - ko:K11477 - - - - ko00000 - - - Cupin_2,Haem_degrading DYD3_k127_787222_12 452637.Oter_2251 1.349e-41 166.0 COG0836@1|root,COG0836@2|Bacteria 2|Bacteria M mannose-1-phosphate guanylyltransferase activity manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase DYD3_k127_787222_15 489825.LYNGBM3L_24180 2.013e-21 96.0 COG5572@1|root,COG5572@2|Bacteria,1GEYF@1117|Cyanobacteria 1117|Cyanobacteria S Predicted integral membrane protein (DUF2282) - - - - - - - - - - - - DUF2282 DYD3_k127_787222_13 264198.Reut_A2690 1.252e-34 138.0 COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2VU9I@28216|Betaproteobacteria,1K6ZW@119060|Burkholderiaceae 28216|Betaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX DYD3_k127_787222_14 580332.Slit_2763 5.926e-30 128.0 COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,2VR01@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 DYD3_k127_787222_7 1229205.BUPH_04631 1.106e-93 316.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKD3@28216|Betaproteobacteria,1K0J2@119060|Burkholderiaceae 28216|Betaproteobacteria S belongs to the UPF0276 family - - - ko:K09930 - - - - ko00000 - - - DUF692 DYD3_k127_787222_16 1137799.GZ78_12655 2.201e-20 93.0 COG5572@1|root,COG5572@2|Bacteria,1PCZI@1224|Proteobacteria,1SDT0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Predicted integral membrane protein (DUF2282) - - - - - - - - - - - - DUF2282 DYD3_k127_787222_21 29581.BW37_05459 1.356e-07 58.0 COG0582@1|root,COG0582@2|Bacteria,1MXUB@1224|Proteobacteria,2VPGU@28216|Betaproteobacteria,478A2@75682|Oxalobacteraceae 28216|Betaproteobacteria L Phage integrase, N-terminal - - - - - - - - - - - - Integrase_1,Phage_int_SAM_2 DYD3_k127_787222_22 1265313.HRUBRA_00414 3.625e-07 52.0 COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1S13U@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec DYD3_k127_791762_3 314285.KT71_00330 2.869e-07 55.0 29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,1SB4D@1236|Gammaproteobacteria,1JC42@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 DYD3_k127_791762_2 472759.Nhal_0366 1.954e-39 154.0 2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,1S4EG@1236|Gammaproteobacteria,1X1R5@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - DYD3_k127_791762_1 323261.Noc_2984 1.439e-41 162.0 2AI7D@1|root,33HQ0@2|Bacteria,1P2AB@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - DYD3_k127_791762_0 493475.GARC_0539 3.584e-83 280.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,1RQNI@1236|Gammaproteobacteria,4643V@72275|Alteromonadaceae 1236|Gammaproteobacteria G Class II aldolase - - - - - - - - - - - - Aldolase_II DYD3_k127_795900_3 518766.Rmar_0947 8.293e-30 123.0 COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 DYD3_k127_795900_1 518766.Rmar_0946 2.166e-72 256.0 COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1FJUC@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Belongs to the ATCase OTCase family argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 ko:K09065,ko:K13043 ko00220,ko01100,ko01230,map00220,map01100,map01230 M00845 R07245,R08937 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N DYD3_k127_795900_0 1144275.COCOR_02389 1.228e-72 258.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria 28221|Deltaproteobacteria F Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase DYD3_k127_795900_2 309807.SRU_2221 1.255e-60 221.0 COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1FJSI@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Lyase_1 DYD3_k127_816966_2 887327.HMPREF0476_1887 4.526e-08 54.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,2KR03@206351|Neisseriales 206351|Neisseriales L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC DYD3_k127_816966_1 243233.MCA1220 1.22e-104 345.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XDV4@135618|Methylococcales 135618|Methylococcales K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg DYD3_k127_816966_0 187272.Mlg_1097 3.75e-185 599.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WW1G@135613|Chromatiales 135613|Chromatiales KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance - - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - ACT_4,HD_4,RelA_SpoT,TGS DYD3_k127_819423_0 317655.Sala_1463 3.056e-204 660.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,2U2KS@28211|Alphaproteobacteria,2KDKA@204457|Sphingomonadales 204457|Sphingomonadales P TonB-dependent receptor plug - - - - - - - - - - - - Plug,TonB_dep_Rec DYD3_k127_819423_1 1282876.BAOK01000001_gene3038 2.458e-77 272.0 COG5505@1|root,COG5505@2|Bacteria,1RAF4@1224|Proteobacteria,2U5HM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 DYD3_k127_848913_2 493475.GARC_4936 5.814e-51 193.0 COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,1S8IP@1236|Gammaproteobacteria,467J8@72275|Alteromonadaceae 1236|Gammaproteobacteria M Peptidase family M23 - - - - - - - - - - - - DUF4124,Peptidase_M23 DYD3_k127_848913_1 1173021.ALWA01000028_gene2013 9.807e-94 313.0 COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria 1117|Cyanobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR DYD3_k127_848913_0 1267533.KB906734_gene3908 1.233e-115 379.0 COG0266@1|root,COG0266@2|Bacteria,3Y71J@57723|Acidobacteria 57723|Acidobacteria L Formamidopyrimidine-DNA glycosylase H2TH domain - - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS DYD3_k127_862940_1 439235.Dalk_4323 8.21e-14 74.0 COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,42T8R@68525|delta/epsilon subdivisions,2WPR7@28221|Deltaproteobacteria,2MMKM@213118|Desulfobacterales 28221|Deltaproteobacteria G Strictosidine synthase - - - - - - - - - - - - Str_synth DYD3_k127_862940_0 1163407.UU7_12409 4.736e-183 591.0 COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X5GF@135614|Xanthomonadales 135614|Xanthomonadales S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 DYD3_k127_862940_2 1484460.JSWG01000012_gene1459 3.476e-06 48.0 COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia 976|Bacteroidetes S PFAM Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 DYD3_k127_911060_1 243233.MCA2694 3.152e-94 315.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XDSF@135618|Methylococcales 135618|Methylococcales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran DYD3_k127_911060_2 1123519.PSJM300_16780 2.08e-86 301.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1Z09D@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily yajR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr DYD3_k127_911060_3 1049564.TevJSym_aa00340 1.218e-58 207.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1J5PI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB DYD3_k127_911060_0 396588.Tgr7_2292 6.263e-207 653.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1WWN1@135613|Chromatiales 135613|Chromatiales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 DYD3_k127_912047_2 396588.Tgr7_0028 3.389e-29 125.0 COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1WWAM@135613|Chromatiales 135613|Chromatiales H Uroporphyrinogen III synthase - - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 DYD3_k127_912047_1 626887.J057_05091 3.293e-34 146.0 COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,467C6@72275|Alteromonadaceae 1236|Gammaproteobacteria H enzyme of heme biosynthesis hemX - 2.1.1.107,4.2.1.75 ko:K02496,ko:K13543 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b3803,iBWG_1329.BWG_3482,iECDH1ME8569_1439.ECDH1ME8569_3682,iECUMN_1333.ECUMN_4327,iECs_1301.ECs4733,iEcDH1_1363.EcDH1_4176,iJO1366.b3803,iJR904.b3803,iPC815.YPO3851,iUMN146_1321.UM146_19140,iY75_1357.Y75_RS18060,iZ_1308.Z5317 HemX DYD3_k127_912047_0 396588.Tgr7_0026 2.662e-80 284.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1X0CU@135613|Chromatiales 135613|Chromatiales H HemY domain protein - - - ko:K02498 - - - - ko00000 - - - HemY_N DYD3_k127_933802_1 1500897.JQNA01000001_gene6422 8.952e-155 501.0 COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,1K1BZ@119060|Burkholderiaceae 28216|Betaproteobacteria C Xanthine dehydrogenase small subunit xdhA - 1.17.1.4 ko:K13481 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 DYD3_k127_933802_0 62928.azo2212 8.839e-223 705.0 COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,2KV6J@206389|Rhodocyclales 206389|Rhodocyclales F COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B - - 1.17.1.4 ko:K13482 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 DYD3_k127_934431_0 702113.PP1Y_AT11594 1.112e-127 417.0 COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,2TSEM@28211|Alphaproteobacteria,2K9JF@204457|Sphingomonadales 204457|Sphingomonadales S KR domain - - - - - - - - - - - - adh_short DYD3_k127_934431_1 1122612.AUBA01000002_gene1696 4.577e-124 402.0 2ED7G@1|root,31A10@2|Bacteria,1NV3Q@1224|Proteobacteria,2URPA@28211|Alphaproteobacteria,2KA1R@204457|Sphingomonadales 204457|Sphingomonadales S SnoaL-like domain - - - - - - - - - - - - SnoaL_4 DYD3_k127_934431_4 863365.XHC_1161 9.815e-69 240.0 COG2267@1|root,COG2267@2|Bacteria,1QUZX@1224|Proteobacteria,1S4PV@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 DYD3_k127_934431_3 279238.Saro_2583 1.004e-92 316.0 2DJGY@1|root,30638@2|Bacteria,1Q6ZZ@1224|Proteobacteria,2UP6A@28211|Alphaproteobacteria,2K92M@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - DYD3_k127_934431_2 1123487.KB892834_gene2746 1.467e-103 351.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VHPI@28216|Betaproteobacteria,2KV27@206389|Rhodocyclales 206389|Rhodocyclales T Double sensory domain of two-component sensor kinase - - - - - - - - - - - - EAL,GGDEF,HAMP,dCache_3 DYD3_k127_939465_0 1121013.P873_00645 5.094e-133 430.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X2XI@135614|Xanthomonadales 135614|Xanthomonadales I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N DYD3_k127_939465_3 493475.GARC_2101 9.521e-40 150.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1T0DU@1236|Gammaproteobacteria,46CKS@72275|Alteromonadaceae 1236|Gammaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain fdx - - ko:K04755 - - - - ko00000 - - - Fer2 DYD3_k127_939465_1 247634.GPB2148_2748 8.525e-77 275.0 COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1J575@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - ANAPC3,TPR_16,TPR_8 DYD3_k127_939465_2 1117315.AHCA01000001_gene2113 1.442e-47 177.0 COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,2Q0AR@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C DYD3_k127_939465_4 861299.J421_1634 1.333e-21 99.0 COG3214@1|root,COG3214@2|Bacteria 2|Bacteria J Protein conserved in bacteria - - - - - - - - - - - - HTH_42 DYD3_k127_948939_5 1122609.AUGT01000009_gene3241 2.577e-13 76.0 COG0784@1|root,COG0784@2|Bacteria,2IKZA@201174|Actinobacteria 201174|Actinobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg DYD3_k127_948939_0 269799.Gmet_2223 3.708e-124 416.0 COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y50@68525|delta/epsilon subdivisions,2WUBF@28221|Deltaproteobacteria 28221|Deltaproteobacteria KT PFAM sigma-54 factor interaction domain-containing protein - - - - - - - - - - - - GAF,GAF_2,GAF_3,HTH_8,PAS_4,Sigma54_activat DYD3_k127_948939_2 1174684.EBMC1_16414 7.589e-62 230.0 COG4719@1|root,COG4719@2|Bacteria,1RARY@1224|Proteobacteria,2U6NU@28211|Alphaproteobacteria,2K437@204457|Sphingomonadales 204457|Sphingomonadales S TIGRFAM conserved repeat domain - - - - - - - - - - - - DUF11 DYD3_k127_948939_4 317655.Sala_1326 2.652e-20 96.0 COG4719@1|root,COG4719@2|Bacteria,1N2CR@1224|Proteobacteria,2UE4C@28211|Alphaproteobacteria,2KE4M@204457|Sphingomonadales 204457|Sphingomonadales S TIGRFAM conserved repeat domain - - - - - - - - - - - - DUF11 DYD3_k127_948939_3 1174684.EBMC1_16404 1.347e-48 188.0 COG4719@1|root,COG4719@2|Bacteria,1R87U@1224|Proteobacteria,2U4JA@28211|Alphaproteobacteria,2K3HI@204457|Sphingomonadales 204457|Sphingomonadales S TIGRFAM conserved repeat domain - - - - - - - - - - - - DUF11 DYD3_k127_948939_1 1232410.KI421421_gene3529 3.019e-91 321.0 COG2067@1|root,COG2885@1|root,COG2067@2|Bacteria,COG2885@2|Bacteria,1MY5K@1224|Proteobacteria 1224|Proteobacteria I long-chain fatty acid transport protein - - - - - - - - - - - - DUF11 DYD3_k127_95449_0 1167632.AJTR01000063_gene68 6.721e-55 209.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,4GY16@90964|Staphylococcaceae 91061|Bacilli E amino acid steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 DYD3_k127_95449_1 1238450.VIBNISOn1_410092 4.425e-30 121.0 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S NnrU protein nnrU - - - - - - - - - - - NnrU DYD3_k127_956998_2 1121015.N789_02215 7.507e-23 102.0 COG0652@1|root,COG0652@2|Bacteria,1QCY4@1224|Proteobacteria,1RRUQ@1236|Gammaproteobacteria,1XCF4@135614|Xanthomonadales 135614|Xanthomonadales M Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - Pro_isomerase DYD3_k127_956998_0 637905.SVI_4321 1.354e-138 455.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,2QAUW@267890|Shewanellaceae 1236|Gammaproteobacteria P Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF DYD3_k127_956998_1 1122603.ATVI01000005_gene3502 5.28e-56 210.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T5SE@1236|Gammaproteobacteria,1XDE6@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 DYD3_k127_967233_2 384765.SIAM614_26116 3.252e-24 105.0 COG0436@1|root,COG0436@2|Bacteria,1R4E6@1224|Proteobacteria,2U35J@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0436 Aspartate tyrosine aromatic aminotransferase - - - - - - - - - - - - Aminotran_1_2 DYD3_k127_967233_3 1321778.HMPREF1982_02132 1.273e-11 70.0 2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - DYD3_k127_967233_1 314345.SPV1_11671 1.368e-42 157.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria 1224|Proteobacteria O Peptidylprolyl isomerase ppiC GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 DYD3_k127_967233_0 1121875.KB907548_gene1616 9.441e-258 809.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 DYD3_k127_979494_0 1297742.A176_06232 6.627e-166 539.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WKYA@28221|Deltaproteobacteria,2YU1C@29|Myxococcales 28221|Deltaproteobacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family kefB - - ko:K03455,ko:K11745,ko:K11747 - - - - ko00000,ko02000 2.A.37,2.A.37.1.1,2.A.37.1.2 - - Na_H_Exchanger,TrkA_N DYD3_k127_979494_3 1121948.AUAC01000003_gene2924 1.987e-67 247.0 COG5306@1|root,COG5306@2|Bacteria 2|Bacteria - - exbB2 - - ko:K03561,ko:K12287 - - - - ko00000,ko02000,ko02044 1.A.30.2.1 - - DUF2341,Laminin_G_3,MotA_ExbB DYD3_k127_979494_2 269799.Gmet_0169 1.894e-76 265.0 COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,42UMC@68525|delta/epsilon subdivisions,2WQJQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S VIT family - - - - - - - - - - - - VIT1 DYD3_k127_979494_4 1121033.AUCF01000006_gene4288 4.503e-48 183.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria,2JS66@204441|Rhodospirillales 204441|Rhodospirillales EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA DYD3_k127_979494_6 1121935.AQXX01000142_gene2266 4.436e-06 49.0 2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_979494_5 1232683.ADIMK_1590 2.427e-24 103.0 COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria,1SCB4@1236|Gammaproteobacteria,468BS@72275|Alteromonadaceae 1236|Gammaproteobacteria T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA DYD3_k127_979494_1 472759.Nhal_1120 2.302e-117 385.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales 135613|Chromatiales J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD DYD3_k127_98798_0 1000565.METUNv1_01576 6.477e-137 443.0 COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,2KVR8@206389|Rhodocyclales 206389|Rhodocyclales EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 DYD3_k127_98798_2 331869.BAL199_17133 3.761e-89 305.0 COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSR9@28211|Alphaproteobacteria,4BSKZ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Ornithine cyclodeaminase/mu-crystallin family - - 1.4.1.1,1.5.1.1,4.3.1.12 ko:K01750,ko:K19244,ko:K19743 ko00250,ko00310,ko00330,ko00430,ko00960,ko01100,ko01110,ko01130,ko01230,map00250,map00310,map00330,map00430,map00960,map01100,map01110,map01130,map01230 - R00396,R00671,R01246,R01249,R02201,R02203 RC00008,RC00135,RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall DYD3_k127_98798_1 1121106.JQKB01000049_gene3064 3.112e-90 307.0 COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria,2JVSA@204441|Rhodospirillales 204441|Rhodospirillales S Chromate resistance exported protein - - - - - - - - - - - - Chrome_Resist DYD3_k127_988521_2 335659.S23_19560 5.271e-44 171.0 COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3JUS1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8 DYD3_k127_988521_3 880070.Cycma_2548 2.249e-22 101.0 2E6K6@1|root,3316Y@2|Bacteria,4NT3A@976|Bacteroidetes,47SXK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - DYD3_k127_988521_1 756272.Plabr_0410 7.53e-74 257.0 COG5587@1|root,COG5587@2|Bacteria,2J2RK@203682|Planctomycetes 203682|Planctomycetes S Conserved hypothetical protein (DUF2461) - - - - - - - - - - - - DUF2461 DYD3_k127_988521_0 1282362.AEAC466_15960 7.125e-112 374.0 COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2KFDT@204458|Caulobacterales 204458|Caulobacterales E Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N DYD3_k127_98998_1 1121015.N789_09065 6.829e-123 419.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X5CR@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis protein pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ DYD3_k127_98998_0 314278.NB231_13346 3.695e-300 987.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales 135613|Chromatiales T response regulator receiver - - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg DYD3_k127_98998_10 1122604.JONR01000020_gene489 9.099e-21 98.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1X71Z@135614|Xanthomonadales 135614|Xanthomonadales NT Two component signalling adaptor domain - - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW DYD3_k127_98998_6 203122.Sde_0467 4.022e-59 213.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,466M1@72275|Alteromonadaceae 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA DYD3_k127_98998_4 187272.Mlg_0224 8.959e-70 246.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1WWUP@135613|Chromatiales 135613|Chromatiales V PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - 3.5.1.28 ko:K03806 - - - - ko00000,ko01000,ko01011 - - - Amidase_2 DYD3_k127_98998_8 713586.KB900536_gene1489 7.938e-34 142.0 COG3725@1|root,COG3725@2|Bacteria,1MYFA@1224|Proteobacteria,1SE2J@1236|Gammaproteobacteria,1WZMR@135613|Chromatiales 135613|Chromatiales V Membrane protein required for beta-lactamase induction - - - ko:K03807 - - - - ko00000 - - - AmpE,CobD_Cbib DYD3_k127_98998_7 305700.B447_11572 3.096e-56 208.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,2KU8W@206389|Rhodocyclales 206389|Rhodocyclales P ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 DYD3_k127_98998_11 1379270.AUXF01000001_gene2445 8.529e-19 92.0 COG1246@1|root,COG1246@2|Bacteria,1ZV2J@142182|Gemmatimonadetes 142182|Gemmatimonadetes E Acetyltransferase (GNAT) domain - - 2.3.1.1 ko:K00619 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 DYD3_k127_98998_3 1384056.N787_05970 1.061e-75 258.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,1S40D@1236|Gammaproteobacteria,1X50D@135614|Xanthomonadales 135614|Xanthomonadales S adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans DYD3_k127_98998_2 713586.KB900536_gene1483 4.457e-88 299.0 COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,1RMVD@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Inositol monophosphatase - - 3.1.3.15 ko:K05602 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P DYD3_k127_98998_5 748247.AZKH_0614 1.731e-61 222.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2VRFJ@28216|Betaproteobacteria,2KW3Z@206389|Rhodocyclales 206389|Rhodocyclales HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran DYD3_k127_98998_9 1101195.Meth11DRAFT_0408 7.774e-23 99.0 28RZD@1|root,2ZEBA@2|Bacteria,1RBEH@1224|Proteobacteria,2VQVV@28216|Betaproteobacteria,2KMKM@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - DYD3_k127_992836_2 682795.AciX8_3725 1.72e-14 87.0 COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia 204432|Acidobacteriia G Belongs to the glycosyl hydrolase 2 family - - - - - - - - - - - - DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3 DYD3_k127_992836_3 670487.Ocepr_1448 0.0001041 55.0 COG2247@1|root,COG2247@2|Bacteria,1WNI9@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M cell wall binding repeat - - - - - - - - - - - - - DYD3_k127_992836_0 420324.KI911999_gene8064 2.561e-286 895.0 28JZZ@1|root,2Z9PZ@2|Bacteria,1N3C6@1224|Proteobacteria,2TSCX@28211|Alphaproteobacteria,1JTZB@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - DYD3_k127_992836_1 1380380.JIAX01000006_gene1021 9.198e-27 112.0 COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,2TV9C@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Aminotransferase - - - - - - - - - - - - Aminotran_1_2 ## 2792 queries scanned ## Total time (seconds): 7.417167663574219 ## Rate: 376.42 q/s